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Search of human proteins with 118572613
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
(2752 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 5347 0.0
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 252 4e-66
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 225 5e-58
gi|91982772 mucin 17 [Homo sapiens] 223 3e-57
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 219 3e-56
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 211 8e-54
gi|60097902 filaggrin [Homo sapiens] 189 4e-47
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 172 5e-42
gi|163965366 nascent polypeptide-associated complex alpha subuni... 167 1e-40
gi|50083281 KIAA1853 protein [Homo sapiens] 162 4e-39
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 160 2e-38
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 160 2e-38
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 150 2e-35
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 148 8e-35
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 146 2e-34
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 145 4e-34
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 144 1e-33
gi|167736355 mucin 4 isoform a [Homo sapiens] 141 8e-33
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 136 2e-31
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 129 4e-29
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 127 2e-28
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 126 3e-28
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 126 3e-28
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 124 2e-27
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 123 2e-27
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 123 2e-27
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 123 3e-27
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 121 8e-27
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 120 2e-26
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 119 3e-26
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 5347 bits (13871), Expect = 0.0
Identities = 2752/2752 (100%), Positives = 2752/2752 (100%)
Query: 1 MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDH 60
MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDH
Sbjct: 1 MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDH 60
Query: 61 ERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTE 120
ERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTE
Sbjct: 61 ERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTE 120
Query: 121 THQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSS 180
THQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSS
Sbjct: 121 THQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSS 180
Query: 181 RSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKS 240
RSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKS
Sbjct: 181 RSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKS 240
Query: 241 KDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPAS 300
KDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPAS
Sbjct: 241 KDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPAS 300
Query: 301 GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG
Sbjct: 301 GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
Query: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
Query: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480
SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR
Sbjct: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480
Query: 481 MGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540
MGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP
Sbjct: 481 MGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540
Query: 541 GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT 600
GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT
Sbjct: 541 GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT 600
Query: 601 RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660
RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS
Sbjct: 601 RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660
Query: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720
RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720
Query: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLS 780
RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLS
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLS 780
Query: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP
Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
Query: 841 HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVK 900
HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVK
Sbjct: 841 HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVK 900
Query: 901 SSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVE 960
SSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVE
Sbjct: 901 SSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVE 960
Query: 961 SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEK 1020
SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEK
Sbjct: 961 SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEK 1020
Query: 1021 SKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSH 1080
SKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSH
Sbjct: 1021 SKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSH 1080
Query: 1081 SESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQS 1140
SESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQS
Sbjct: 1081 SESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQS 1140
Query: 1141 DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSL 1200
DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSL
Sbjct: 1141 DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSL 1200
Query: 1201 VFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSEL 1260
VFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSEL
Sbjct: 1201 VFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSEL 1260
Query: 1261 KEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNS 1320
KEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNS
Sbjct: 1261 KEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNS 1320
Query: 1321 PLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG 1380
PLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG
Sbjct: 1321 PLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG 1380
Query: 1381 HSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR 1440
HSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR
Sbjct: 1381 HSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR 1440
Query: 1441 SGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP 1500
SGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP
Sbjct: 1441 SGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP 1500
Query: 1501 SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESD 1560
SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESD
Sbjct: 1501 SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESD 1560
Query: 1561 SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS 1620
SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS
Sbjct: 1561 SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS 1620
Query: 1621 SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT 1680
SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT
Sbjct: 1621 SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT 1680
Query: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR
Sbjct: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
Query: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800
SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR
Sbjct: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800
Query: 1801 RQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAP 1860
RQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAP
Sbjct: 1801 RQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAP 1860
Query: 1861 WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR 1920
WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR
Sbjct: 1861 WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR 1920
Query: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR 1980
RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR
Sbjct: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR 1980
Query: 1981 RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK 2040
RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK
Sbjct: 1981 RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK 2040
Query: 2041 RSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS 2100
RSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS
Sbjct: 2041 RSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS 2100
Query: 2101 GSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGP 2160
GSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGP
Sbjct: 2101 GSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGP 2160
Query: 2161 GPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL 2220
GPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL
Sbjct: 2161 GPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL 2220
Query: 2221 RTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPS 2280
RTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPS
Sbjct: 2221 RTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPS 2280
Query: 2281 AVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVG 2340
AVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVG
Sbjct: 2281 AVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVG 2340
Query: 2341 PRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPP 2400
PRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPP
Sbjct: 2341 PRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPP 2400
Query: 2401 LLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 2460
LLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSR
Sbjct: 2401 LLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 2460
Query: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA
Sbjct: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
Query: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVP 2580
LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVP
Sbjct: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVP 2580
Query: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 2641 SSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR 2700
SSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR
Sbjct: 2641 SSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR 2700
Query: 2701 PSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
PSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP
Sbjct: 2701 PSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 252 bits (643), Expect = 4e-66
Identities = 232/670 (34%), Positives = 313/670 (46%), Gaps = 92/670 (13%)
Query: 37 KGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRL 96
+ EEELR E LVKR + +ILDHERKRRVEL+C+EL+EMMEEQGY E++I++KV TFR
Sbjct: 34 RAEEELRAAEPGLVKRAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQ 93
Query: 97 MLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRR 156
ML+EK+ +E+ PG V ET +L E E E A F D VD
Sbjct: 94 MLMEKE-GVLTREDRPGGH-IVAETPRLTEGAEPGLE--YAPFDDDDGPVD--------- 140
Query: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKK------KKDRGRRSE----SSSPR 206
+ + Y SSSS SP PK+KKKKK +K R SE SSSP
Sbjct: 141 -CDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPL 199
Query: 207 RERKKSSKK-KKHRSESES-KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST 264
R++KKS KK ++ RS+S S +KR+HRS + K KRK K+K++KR + +P +S R +
Sbjct: 200 RKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGS 259
Query: 265 SADSASSSDTSRSRSRSAAAKTH---------TTALAGRSPSPASGRRGEGDAPFSEPGT 315
S + SS S SRS S + H + RSPSP+ G G
Sbjct: 260 SHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ 319
Query: 316 TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP-PAPTPLLAERH 374
S P +A P P + + + +A P+P P R P P AP+ ++
Sbjct: 320 RSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTP-PARGKESPSPRSAPS---SQGR 375
Query: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHA 434
GG A + S +S + +P + + P+ + S S + S +
Sbjct: 376 GGRAAGGAGRRRRRRRRRRRSRSSAS---APRRRGRRRPRPAPPRGSSRSLSRARSSSDS 432
Query: 435 SSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR 494
S +P P P PGS R + HG+ +++ P R S SP+ GR
Sbjct: 433 GSGRGAPGPGPEPGSER--------GHGGHGKRAKER-----PPRARPASTSPSPGAHGR 479
Query: 495 ---------SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545
SRS P R S SRSP RSRSA++ R SP RS SP++P S
Sbjct: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEK--RPHSP---SRSPSPKKP---LS 531
Query: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605
R+ GR+R HS + ATR R RSR+ + + R +P+ R T R+R
Sbjct: 532 RDKDGEGRAR-------HSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRP- 583
Query: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSP----ARRSGRSRSRTPARRGRSRSR 661
P R +P+ S S RS SRSP + S SRS R RS SR
Sbjct: 584 --IPYYR-----PSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSR 636
Query: 662 TPARRGRSRS 671
TP+ SRS
Sbjct: 637 TPSPSYHSRS 646
Score = 134 bits (337), Expect = 1e-30
Identities = 158/555 (28%), Positives = 226/555 (40%), Gaps = 79/555 (14%)
Query: 1461 GSSPGMKDIPRTPSRGRSECD---------------------SSPEPKALPQTPRPRSRS 1499
G+ PG++ P G +CD +SP PK + RS
Sbjct: 122 GAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRS 181
Query: 1500 PSSPELNNKCLTPQRERSGSESSVDQKTVA-RTPLGQRSRSGSSQELDVKPSASPQERSE 1558
L ++C GS S + +K + + RS SGS ++ + +S +R E
Sbjct: 182 RKKRRLESEC------SCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKE 235
Query: 1559 SDSSPDSKAKTRTPLRQRSR--SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
+ + T +P R+ R SGSS S S RS S SP+ +D+ R +S
Sbjct: 236 KNKEK-KRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS 294
Query: 1617 GSDSSPEPKAPAPRALPRRSR-SGSSSKGRGPSPEGSSSTESSPEHP--PKSRTARRGSR 1673
SP P + P+R+ SG S G P S S P+ P P R + +
Sbjct: 295 SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRP---GSAHSPPDKPSSPSPRVRDKAAA 351
Query: 1674 SSPEPKTKSRTPPRRRSSRSSP-----------ELTRKARLSRRSRSASSSPETRSRTPP 1722
++P P + + P RS+ SS R+ R RRSRS++S+P R R P
Sbjct: 352 AAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRP 411
Query: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782
R PA SSR A S + R P P+P + +R K
Sbjct: 412 R-----------PAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKE 460
Query: 1783 RTTRRRDRSGSSQSTSRRRQ-----RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
R R R S S + R+ +S SRS R S SRSP++ SR++ +R
Sbjct: 461 RPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSS---SRSPSKSR-SRSAEKR 516
Query: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRR-SRSRTSPVS 1896
SR+P + SR + + S + A+ A RRSRS +P+ RRR S S P
Sbjct: 517 PHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRA-RRRSRSYSPIRKRRRDSPSFMEPRR 575
Query: 1897 RRRSRSRTSVTRRRSRSRASPV------SRRRSRSRTPPVTRRRSRSRTPTTRRRSR--S 1948
+R R R S S +S +R SRS +P + SR+ TR R+R S
Sbjct: 576 ITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPS 635
Query: 1949 RTP-PVTRRRSRSRT 1962
RTP P RS S +
Sbjct: 636 RTPSPSYHSRSSSES 650
Score = 128 bits (321), Expect = 9e-29
Identities = 161/518 (31%), Positives = 209/518 (40%), Gaps = 68/518 (13%)
Query: 1557 SESDSSPDSKAKTRTPLRQRSRS-----------GSSP-EVDSKSRLSPRRSRSGSSPEV 1604
S S S P K K + +RSR SSP KS RR RS S
Sbjct: 161 SSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRR 220
Query: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH-PP 1663
K + R+ + + E K P + RRS SS PS S SP P
Sbjct: 221 KRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSP 280
Query: 1664 KSRTARRGSRSSPEPKTKSRTP-PRRRSSRSSPELT-----RKARLSRRSRSASSSPETR 1717
K R G ++ + + SR+P P S SP+ R R SA S P+
Sbjct: 281 KHRD--EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKP 338
Query: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777
S PR R + ++P P + + S RSA PS + RG + +
Sbjct: 339 SSPSPRVRDKAAAAAPTPPARGKESPSPRSA--------------PSSQGRGGRAAGGAG 384
Query: 1778 RREKTRTTRRRDRSGSSQSTSRRRQR---------SRSRSRVTRRRRGGSGYHSRSPARQ 1828
RR + R RRR RS +S R R+R SRS SR GSG + P +
Sbjct: 385 RRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPE 444
Query: 1829 ESSRTS--SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR 1886
S +R + R PP +R S TSP+P R R P SRS P
Sbjct: 445 PGSERGHGGHGKRAKER-PPRARPAS---TSPSPGAHGR-RGGPEGKSSSRSPGP----- 494
Query: 1887 RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946
RS +S S +SRSR++ R S SR+ S ++ SR R S TR R
Sbjct: 495 HPRSWSSSRSPSKSRSRSAEKRPHSPSRSP--SPKKPLSRDKDGEGRARHSEAEATRARR 552
Query: 1947 RSRT-PPVTRRRSRSRTPPVTRRRSRSRTSPITRRR-----SRSRTSPVTRRRSRSRT-S 1999
RSR+ P+ +RR S + RR + +R PI R S S S RS SR+ S
Sbjct: 553 RSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPS 612
Query: 2000 PVTRRRSRSRTSPVTRRRSR--SRTP-PAIRRRSRSRT 2034
P S S S TR R+R SRTP P+ RS S +
Sbjct: 613 PGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSES 650
Score = 127 bits (320), Expect = 1e-28
Identities = 151/558 (27%), Positives = 218/558 (39%), Gaps = 65/558 (11%)
Query: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTP 609
R R + S S SP + + + + RR R + R + S +P R++ +S
Sbjct: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKK 208
Query: 610 ARRGRSRSRTPARRRSRTRSP-VRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR 668
RR RS S + +RR R+RS +R+ +++ R S R R S +P+
Sbjct: 209 HRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSH 268
Query: 669 -SRSRTPARRSGRSRS--RTPARRGRSRSRTPR-RGRSRSRSLVRRGRSHSRTPQRRGRS 724
S SR+P+R S + R R + S SR+P G S S R G S R+ GR
Sbjct: 269 YSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRP 328
Query: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
GS+ +K + R R ++ + R + SPRS S+ R+ G+
Sbjct: 329 GSAHSPPDKPSSPSPRVRDKAAAA---APTPPARGKESPSPRSAPSSQGRGGRAAGGAGR 385
Query: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKV 844
+++ + RRSRS +S P+ + R PR + PP+ S++ SR SS S +
Sbjct: 386 --RRRRRRRRRRSRSSASAPRRRGRRRPRPA------PPRGSSRSLSRARSSSDSGSGRG 437
Query: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD--PELKSRTPSRHSCSGSSPPRVKSS 902
G P GS E+ + E P P S +P H G + S
Sbjct: 438 APGPGPEPGS-------ERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR 490
Query: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962
+P S SSS P S +R HS S SPSP + SR R+
Sbjct: 491 SPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRA---------- 540
Query: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP----PGPSLSGSKSPCPQ 1018
R+S + E + S S SP K + +P P S K P P
Sbjct: 541 ---RHSEA-----------EATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPY 586
Query: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQ 1078
+ S SC S S PG S+ SS S RS T SP
Sbjct: 587 YRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSS--------RSHGTRSRTRSP---- 634
Query: 1079 SHSESPSLQSKSQTSPKG 1096
S + SPS S+S + G
Sbjct: 635 SRTPSPSYHSRSSSESGG 652
Score = 115 bits (289), Expect = 5e-25
Identities = 163/552 (29%), Positives = 227/552 (41%), Gaps = 81/552 (14%)
Query: 457 PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516
P S R H R R K S + S SP K+ + K GH RSR RR
Sbjct: 144 PASCYRGH-RGYRTKHWSSS-------SASPPPKKKKKK------KGGHRRSRKK--RRL 187
Query: 517 RSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQ-RRGRSRSARRGRSHSRSPATRGRSRS 575
S G S +++ +S R S S + + RR RSRS++ R R + S
Sbjct: 188 ESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTES 247
Query: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635
P RR S S S + + S SR+P+R +P R ++ +R S
Sbjct: 248 --PGRRSHRHS----SGSSHSPSLSSHYSDSRSPSR------LSPKHRDEGRKTGSQRSS 295
Query: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRS-RTPARRSGRSRSRTPARRGRSRS 694
SRSP+ SG S +P R G S R+ A GR S +P + R + +
Sbjct: 296 GSRSPS-PSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAP 354
Query: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754
P RG+ RS + R GR+ + R+ + R +RRSRS++S ++ R
Sbjct: 355 TPPARGKESPSP-----RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRR 409
Query: 755 SSR----RSRSLSSPRSKAKSRLSLRRSLSGSSPCP----------KQKSQTPPR----- 795
R R S S R+++ S R G P P K+ + PPR
Sbjct: 410 RPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAS 469
Query: 796 -------RSRSGSSQPKAKSRT--PPRRSRSSSSPPPKQKSKTPSRQSHS-SSSPHPKVK 845
R G + K+ SR+ P RS SSS P K +S++ ++ HS S SP PK K
Sbjct: 470 TSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPK-K 528
Query: 846 SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP 905
+ + G + + ++ +RRS S P K R R S S P R+ +S
Sbjct: 529 PLSRDKDGEGRARHSEAEATRARRRS---RSYSPIRKRR---RDSPSFMEPRRI-TSARK 581
Query: 906 RQSPSRSSSPQPKVKAIISP-RQRSHSGSSSPSPSR--VTSRTTPRRSRSVSPCSNVESR 962
R P SP + S RSHS S SP S +SR+ RSR+ SP SR
Sbjct: 582 RPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSP-----SR 636
Query: 963 LLPRYSHSGSSS 974
HS SSS
Sbjct: 637 TPSPSYHSRSSS 648
Score = 111 bits (277), Expect = 1e-23
Identities = 158/564 (28%), Positives = 222/564 (39%), Gaps = 80/564 (14%)
Query: 1604 VKDKPRAAPRAQSGSDSSP--EPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH 1661
V + PR A+ G + +P + P P G RG + SS+ +SP
Sbjct: 113 VAETPRLTEGAEPGLEYAPFDDDDGPVDCDCPASCYRGH----RGYRTKHWSSSSASP-- 166
Query: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP 1721
PPK + ++G + K R SSP +K + + R S S R R
Sbjct: 167 PPKKKKKKKGGHR--RSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKR-- 222
Query: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781
RHR S + EK++ +R + S R G S SP L S SR
Sbjct: 223 -RHRSRSSKCKRK--EKNKEKKRPHTESPGRRSHRHSSGSSHSPS---LSSHYSDSRSPS 276
Query: 1782 TRTTRRRD---RSGSSQST-SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
+ + RD ++GS +S+ SR S + +R GGSG S + + S S
Sbjct: 277 RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPD 336
Query: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRSRS-RASPATHRRSRSRTPLISRRRSRSRTSPVS 1896
+ + + + T PA K S S R++P++ R RRR R R
Sbjct: 337 KPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRR---- 392
Query: 1897 RRRSRSRTSVTRRRSRSRASPV-----SRRRSRSRTP---------------PVTRR--- 1933
RRRSRS S RRR R R P SR SR+R+ P + R
Sbjct: 393 RRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452
Query: 1934 ----RSRSRTPTTRRRSRSRTPPVTRRR------SRSRTPPVTRRRSRSRTSPITRRRSR 1983
R++ R P R S S +P RR S SR+P R S SP R
Sbjct: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS 512
Query: 1984 SRTSPVTRRRSRSRTSPVTRRRS---RSRTSPV----TRRRSRSRTPPAIRRRSRSRTPL 2036
+ P + RS S P++R + R+R S RRRSRS +P IR+R R
Sbjct: 513 AEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSP--IRKRRRDSPSF 570
Query: 2037 LPRKR--SRSRSPLAIRRRSRSRTP---RTARGKRSLTRSPPAIRRRSASGSSSDRSRSA 2091
+ +R S + P+ R S S + + RS +RSP + S S +RS
Sbjct: 571 MEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRS- 629
Query: 2092 TPPATRNHSGSRTPPVALNSSRMS 2115
R S SRTP + +S S
Sbjct: 630 -----RTRSPSRTPSPSYHSRSSS 648
Score = 105 bits (263), Expect = 5e-22
Identities = 149/506 (29%), Positives = 189/506 (37%), Gaps = 107/506 (21%)
Query: 1370 DMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKD 1429
+ K T S G S S +G S + S+SS D+ RS S SP+ +D
Sbjct: 239 EKKRPHTESPGRRSHRHS------SGSSHSPSLSSHYSDS--------RSPSRLSPKHRD 284
Query: 1430 GLPRTPSRRSRSGSSPGLRDGS--GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487
+T S+RS SP GS G+P R+ SG G GR SP K
Sbjct: 285 EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHG-------GRPGSAHSPPDK 337
Query: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
P +P PR R ++ A TP + S S
Sbjct: 338 --PSSPSPRVRDKAA------------------------AAAPTPPARGKESPS------ 365
Query: 1548 KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDK 1607
P ++P + + + R R+R RS SS S R RR + P +
Sbjct: 366 -PRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA---SAPRRRGRRRPRPAPP--RGS 419
Query: 1608 PRAAPRAQSGSDSSPEPKAPAPRALPRRSRS----GSSSKGRGPSPEGSSSTESSPEHPP 1663
R+ RA+S SDS AP P P R G +K R P +S++ S H
Sbjct: 420 SRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAH-- 477
Query: 1664 KSRTARRGSRSSPEPKTKSRTP---PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRT 1720
G R PE K+ SR+P PR SS SP S+S S S E R +
Sbjct: 478 -------GRRGGPEGKSSSRSPGPHPRSWSSSRSP-----------SKSRSRSAEKRPHS 519
Query: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
P RSPS P +K R R S + T R RS S P +R S S E
Sbjct: 520 P---SRSPSPKKPLSRDKDGEGRARHS----EAEATRARRRSRSYSPIRKRRRDSPSFME 572
Query: 1781 KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG 1840
R T R R S S S + R HSRSP+ S + S R G
Sbjct: 573 PRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRS------HSRSPSPGHSHGSYSSRSHG 626
Query: 1841 RSRTPPTSRKRSRSRTSPAPWKRSRS 1866
SR RS SRT P+P SRS
Sbjct: 627 -----TRSRTRSPSRT-PSPSYHSRS 646
Score = 93.6 bits (231), Expect = 2e-18
Identities = 105/364 (28%), Positives = 148/364 (40%), Gaps = 51/364 (14%)
Query: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215
R A P +P P VR+ +++ +PTP + K ES SPR
Sbjct: 327 RPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGK----------ESPSPR--------- 367
Query: 216 KKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTS 275
S S+ R R+ +R+ + ++R+RSRS+ AP+ R R A SS S
Sbjct: 368 ----SAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSS-RS 422
Query: 276 RSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPY 335
SR+RS++ G P P S RG G G + +RP A+ PS
Sbjct: 423 LSRARSSSDSGSGRGAPGPGPEPGS-ERGHGGH-----GKRAKERPPRARPASTSPSPGA 476
Query: 336 EDKDKDKKEKSATR-PSPSPERSSTGPEPPAPTPLLAER--HGGSPQPLATTPLSQEPVN 392
+ + KS++R P P P S+ P AE+ H S P PLS++
Sbjct: 477 HGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536
Query: 393 PP----SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKP--APA 446
SEA TR R +S P SP +P +++ S+ + P P P+
Sbjct: 537 EGRARHSEAEATRARRRSRSYS--PIRKRRRDSPSFMEPRRIT----SARKRPIPYYRPS 590
Query: 447 PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS 506
P S SS S RSH R+ S H+ RS + R SR TP+ HS
Sbjct: 591 PSSSSSCLSSDYS-TRSHSRSP---SPGHSHGSYSSRSHGTRSRTRSPSR--TPSPSYHS 644
Query: 507 RSRS 510
RS S
Sbjct: 645 RSSS 648
Score = 88.6 bits (218), Expect = 8e-17
Identities = 127/510 (24%), Positives = 186/510 (36%), Gaps = 78/510 (15%)
Query: 647 SRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRS 706
S S +P + + + + RR R + R + S S S P R+ + + RR RS S S
Sbjct: 161 SSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSS--PLRKKKKSVKKHRRDRSDSGS 218
Query: 707 LVRRGRSHSRTPQRRGRSGSSSERK-----NKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761
RR R H + R + E+K + R S R S +S S S RS S
Sbjct: 219 --RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPS 276
Query: 762 LSSPRSKAKSRLSLRRSLSGS-SPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS 820
SP+ + + R + + SGS SP P S + GS Q +S R S+ S
Sbjct: 277 RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ---RSGAHGGRPGSAHS 333
Query: 821 PPPKQKSKTPS-RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP 879
PP K S +P R ++++P TPP +G SP + R
Sbjct: 334 PPDKPSSPSPRVRDKAAAAAP-------TPPARGK-ESPSPRSAPSSQGRGGRAAGGAGR 385
Query: 880 ELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS 939
+ R R S S +S PR + PR +P R SS +++ R S SGS +P
Sbjct: 386 RRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSS-----RSLSRARSSSDSGSGRGAPG 440
Query: 940 RVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKV 999
+ R H G K E PPR + S SP P
Sbjct: 441 PGPEPGSER-------------------GHGGHG----KRAKERPPR-ARPASTSPSPGA 476
Query: 1000 KAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKG 1059
+ S S+SP P +S S S P +S +
Sbjct: 477 HGRRGGPEGKSSSRSPGPHPRSWSS-----------------SRSPSKSRSRSAE----- 514
Query: 1060 QSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRG 1119
+ SP P R E + S+++ + RSRS SP+ + SP +
Sbjct: 515 KRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPR 574
Query: 1120 EFSAS-----PMLKSGMSPEQSRFQSDSSS 1144
+++ P + S S SD S+
Sbjct: 575 RITSARKRPIPYYRPSPSSSSSCLSSDYST 604
Score = 87.4 bits (215), Expect = 2e-16
Identities = 124/429 (28%), Positives = 166/429 (38%), Gaps = 84/429 (19%)
Query: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782
+H S S S P +K + RRS R ++ G S + +++K+
Sbjct: 157 KHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLR-----------KKKKS 205
Query: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS 1842
RRDRS S SRR++R RSRS +R+ + P + R S R G S
Sbjct: 206 VKKHRRDRSDSG---SRRKRRHRSRSSKCKRKEKNK--EKKRPHTESPGRRSHRHSSGSS 260
Query: 1843 RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS 1902
+P S S SR S SR SP HR +T S+R S SR SP S
Sbjct: 261 HSPSLSSHYSDSR--------SPSRLSPK-HRDEGRKTG--SQRSSGSR-SPSPSGGSGW 308
Query: 1903 RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
+ S R+ R + +PP + S +P R ++ + P T
Sbjct: 309 GSPQRNGGSGQRSGAHGGRPGSAHSPP---DKPSSPSPRVRDKAAAAAP----------T 355
Query: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRT 2022
PP R + SP R++P ++ R RRR R R RRRSRS
Sbjct: 356 PPA---RGKESPSP--------RSAPSSQGRGGRAAGGAGRRRRRRRR----RRRSRSSA 400
Query: 2023 PPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTA---------------RGKRS 2067
RR R P PR SRS S R S S + R A GKR+
Sbjct: 401 SAPRRRGRRRPRPAPPRGSSRSLS--RARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRA 458
Query: 2068 LTRSPPAIRRRSAS---------GSSSDRSRSATP-PATRNHSGSRTPPVALNSSRMSCF 2117
R PP R S S G +S S +P P R+ S SR+P + + S
Sbjct: 459 KER-PPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP 517
Query: 2118 SRPSMSPTP 2126
PS SP+P
Sbjct: 518 HSPSRSPSP 526
Score = 73.2 bits (178), Expect = 3e-12
Identities = 92/364 (25%), Positives = 133/364 (36%), Gaps = 42/364 (11%)
Query: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
R + +P + S +PS SS + S S L P S S SR
Sbjct: 242 RPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSR--- 298
Query: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
+P GS S + +G H G PG HS +P + +
Sbjct: 299 -SPSPSGGSGWGSPQRNGGSGQRSGAHGGR-----PGSAHSPPDKPSSPS---------- 342
Query: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
P ++++++ + + S S S+ SS G + G+ + +R S
Sbjct: 343 --PRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA 400
Query: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
AP+ R R P P P + RS S + SSS S S + S +
Sbjct: 401 SAPRRRGR--RRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRA 458
Query: 2644 SSS---SSPSPAKPGPQALPKPASP------KKPPPGERRSRSPRKPIDS-LRDSRSLSY 2693
+ P+ P P A + P + P P R S R P S R + +
Sbjct: 459 KERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPH 518
Query: 2694 SPVERRRPSP-QPSPRDQQSSSSERGS-----RRGQRGDSRSPSHKRRRETPS-PRPMRH 2746
SP R PSP +P RD+ R S R +R S SP KRRR++PS P R
Sbjct: 519 SP--SRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRI 576
Query: 2747 RSSR 2750
S+R
Sbjct: 577 TSAR 580
Score = 70.5 bits (171), Expect = 2e-11
Identities = 71/238 (29%), Positives = 84/238 (35%), Gaps = 22/238 (9%)
Query: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
K+RR S S SSS S S S S KR K
Sbjct: 183 KKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKR--------K 234
Query: 2588 EAVREG-RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS------------SSSSSS 2634
E +E RP +P +R R SS SS S S SS S S S S + S S
Sbjct: 235 EKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS 294
Query: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694
S S S S S S SP + G A +P P P +RD ++ + +
Sbjct: 295 SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRD-KAAAAA 353
Query: 2695 PVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
P R PSPR SS G G G R +RRR S R R R P
Sbjct: 354 PTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRP 411
Score = 61.6 bits (148), Expect = 1e-08
Identities = 68/257 (26%), Positives = 90/257 (35%), Gaps = 40/257 (15%)
Query: 2503 HSDVGEPPAS---TGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS 2559
H D G S +G++ PS +R+ S S + S+ S S
Sbjct: 282 HRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSP 341
Query: 2560 SS---DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
S D ++ P P K PSP AP R GR +R+RR S SS+
Sbjct: 342 SPRVRDKAAAAAPTPPARG-KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA 400
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP-AKPGPQALPKPASPKKPPPGERRS 2675
S+ + SS S S + SSS S S PGP P PG R
Sbjct: 401 SAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPG----------PEPGSERG 450
Query: 2676 RSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRR 2735
+ + RP PR + +S+S G+RG P K
Sbjct: 451 HG--------------GHGKRAKERP-----PRARPASTSPSPGAHGRRG---GPEGKSS 488
Query: 2736 RETPSPRPMRHRSSRSP 2752
+P P P SSRSP
Sbjct: 489 SRSPGPHPRSWSSSRSP 505
Score = 60.1 bits (144), Expect = 3e-08
Identities = 67/257 (26%), Positives = 86/257 (33%), Gaps = 22/257 (8%)
Query: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
E S G+ P K RR S S S S SS S
Sbjct: 188 ESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTES 247
Query: 2568 LPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK--------RRSSSSSSSSSSSSS 2619
P + S +P+ + R P K + +RSS S S S S S
Sbjct: 248 -PGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGS 306
Query: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE-RRSRSP 2678
S + S S + S+ S P+ P P+ K A+ PP + S SP
Sbjct: 307 GWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSP 366
Query: 2679 RK-PIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQ----RGDSRSPSHK 2733
R P R R+ + RRR + R S+ RG RR + RG SRS S
Sbjct: 367 RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA 426
Query: 2734 RR-------RETPSPRP 2743
R R P P P
Sbjct: 427 RSSSDSGSGRGAPGPGP 443
Score = 60.1 bits (144), Expect = 3e-08
Identities = 113/435 (25%), Positives = 156/435 (35%), Gaps = 68/435 (15%)
Query: 2312 TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM 2371
+GS P+ +++ S SR+P + + R T +GSR+ + + S +
Sbjct: 257 SGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRK---TGSQRSSGSRSPSPSGGSGWGSPQR 313
Query: 2372 ---APALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP-PSAPSQSRMTSERAPSP 2427
+ SGA+ P S ++ S SP + D+A + P P A + + APS
Sbjct: 314 NGGSGQRSGAHGGRPGSAHSPPDKPSS-PSPRVRDKAAAAAPTPPARGKESPSPRSAPSS 372
Query: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487
R G+A + + + R S+ S R + P S S + A ++S +
Sbjct: 373 QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDS 432
Query: 2488 GDHNGMLSVPAPGVP------HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541
G G P PG H G+ + A + P R SSS
Sbjct: 433 GSGRG---APGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489
Query: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT-PAPKEAVREGRP----P 2596
S S SSS S S S P P R PSP P ++ EGR
Sbjct: 490 RSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPS----RSPSPKKPLSRDKDGEGRARHSEA 545
Query: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS-------------SSSSSSSSSSSSSS 2643
E T A+R+ RS S S S +S SSSSS SS S+
Sbjct: 546 EATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTR 605
Query: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
S S SPSP G SRS +RS + R PS
Sbjct: 606 SHSRSPSPGHSH---------------GSYSSRS--------HGTRSRT------RSPSR 636
Query: 2704 QPSPRDQQSSSSERG 2718
PSP SSSE G
Sbjct: 637 TPSPSYHSRSSSESG 651
Score = 57.4 bits (137), Expect = 2e-07
Identities = 114/466 (24%), Positives = 159/466 (34%), Gaps = 78/466 (16%)
Query: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
S SS+SPPPK+K K + H S +++S GS + + ++SV RR
Sbjct: 160 SSSSASPPPKKKKK--KKGGHRRSRKKRRLESECSC--GSSSPLRKKKKSVKKHRRD--R 213
Query: 875 SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSS 934
S K R SR S + P +SP R R HS S
Sbjct: 214 SDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGR--------------RSHRHSSGS 259
Query: 935 SPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKP--ETPPRQSHSGS 992
S SPS + + R +SP E R SGS SP +P R SG
Sbjct: 260 SHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ 319
Query: 993 -------------------ISPYPKVK---AQTPPGPSLSGSKSPCPQEKSKDSLVQSCP 1030
SP P+V+ A P P G +SP P+ Q
Sbjct: 320 RSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSS---QGRG 376
Query: 1031 GSLSLCAGVK-------------SSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVR 1077
G + AG + +S P +G S++ RS + S R
Sbjct: 377 GRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR 436
Query: 1078 QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRG--------EFSASP---- 1125
+ P S+ G R++ P AS SP G S SP
Sbjct: 437 GAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHP 496
Query: 1126 -MLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK 1184
S SP +SR +S + P S S + L + E A + +AT + R +
Sbjct: 497 RSWSSSRSPSKSRSRS-AEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSR 555
Query: 1185 DKFSPFPVQDRPESSLVFKDTLR-TPPRERSGAGSSPETKEQNSAL 1229
S P++ R S F + R T R+R P +S L
Sbjct: 556 ---SYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCL 598
Score = 43.9 bits (102), Expect = 0.002
Identities = 123/547 (22%), Positives = 189/547 (34%), Gaps = 64/547 (11%)
Query: 2002 TRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPL-----AIRRRSRS 2056
T+ S S SP +++ + + RRSR + L S SPL ++++ R
Sbjct: 156 TKHWSSSSASPPPKKKKKKKGG---HRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRD 212
Query: 2057 RTPRTARGK-RSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
R+ +R K R +RS R+ + S + R+ SGS P +L+S
Sbjct: 213 RSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSP-SLSSHYSD 271
Query: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN 2175
S +SP D R G G SR+P +GGS P QR+
Sbjct: 272 SRSPSRLSPKHRDEGRKTGSQRSSG-SRSP----SPSGGSGWGSPQRNGGSGQRSGAHGG 326
Query: 2176 HAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235
G+A PP ++ + A P T PA S P +
Sbjct: 327 RP-------------GSAHSPPDKPSSPSPRVRDKAAAAAP-----TPPARGKESPSPRS 368
Query: 2236 SAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAV 2295
+ ++ A A R S +A AP PR PA
Sbjct: 369 APSSQGRGG-------RAAGGAGRR--RRRRRRRRRSRSSASAPRRRGRRRPR----PAP 415
Query: 2296 NLAGARTPAALAALSLTGSGT-PPTAANYPSSSRTPQAPASANLVGPRSAH--ATAPVNI 2352
+R+ + + S +GSG P P S R P A +T+P
Sbjct: 416 PRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPG 475
Query: 2353 AGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS 2412
A R P +S+R +P + +S R P + R S P R+ S P
Sbjct: 476 AHGRRG---GPEGKSSSR-SPGPHPRSWSSSRSPSKSRSR-SAEKRPHSPSRSPSPKKPL 530
Query: 2413 APSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV--- 2469
+ + R + + S+S P + + SP +F + R A+ P+
Sbjct: 531 SRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSP---SFMEPRRITSARKRPIPYY 587
Query: 2470 AGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE 2529
S S SS +++ S+ P+PG H T ++ S P+
Sbjct: 588 RPSPSSSSSCLSSDYSTRSHSRS----PSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYH 643
Query: 2530 RRSSSSS 2536
RSSS S
Sbjct: 644 SRSSSES 650
Score = 34.7 bits (78), Expect = 1.3
Identities = 33/136 (24%), Positives = 46/136 (33%), Gaps = 2/136 (1%)
Query: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657
P P K+K++ S S S SSS S S S S K +
Sbjct: 166 PPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHR 225
Query: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER 2717
+ K+ ++R + S R S S+SP S SP +
Sbjct: 226 SRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDE 285
Query: 2718 GSRRGQR--GDSRSPS 2731
G + G + SRSPS
Sbjct: 286 GRKTGSQRSSGSRSPS 301
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 225 bits (573), Expect = 5e-58
Identities = 601/2745 (21%), Positives = 920/2745 (33%), Gaps = 391/2745 (14%)
Query: 250 STTPAPKSRRAHRSTSADSASSSDTSRSR-SRSAAAKTHTTALAGRSPSPASGRRG---- 304
+T P+ + + A S +S S SR + + T TT L G +P+ +
Sbjct: 1385 TTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY 1444
Query: 305 ----EGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
DA S TTS+ T+ QP S + D S P+ SS G
Sbjct: 1445 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 1504
Query: 361 PEPPAPTP--LLAERHG-------GSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK 411
+P A G SP TT L + + + T S S
Sbjct: 1505 STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 1564
Query: 412 LPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDK 471
+SS S+ + T SSS +P P + E+S++ S+ S
Sbjct: 1565 TLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS-----TPT 1619
Query: 472 SHSHTPSRRMGRSRSPATAKRGRSRSRT---PTKRGHSRSRSPQWRRSRSAQRWGRSRSP 528
+H S +GRS T + T PT R + S + SP
Sbjct: 1620 THFSASSTTLGRSEESTTVHSSPGATGTALFPT------------RSATSVLVGEPTTSP 1667
Query: 529 QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588
G + + PG +T G S + S RSP T S T + G S T
Sbjct: 1668 ISSGSTETTALPG-----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS--GVSEEST 1720
Query: 589 PARRRSRSRTPTRRRSRSRTPARRGRSR-SRTPARRRSRTRSPVRRRSRSRSPARRSGRS 647
+ R S T + P S S + T SP + S P + S
Sbjct: 1721 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 1780
Query: 648 RSRTP---------ARRGRSRSRTPARRGRSRSRT---PARRSGRSRSRTPARRGRSRSR 695
+ G + TP T PA + R T + S
Sbjct: 1781 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKD 1840
Query: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRIS 755
T + + + V + +P SS+ + S +S RS S + S ++
Sbjct: 1841 TMPAPPTTTSAFVELSTTSHGSP-------SSTPTTHFSASSTTLGRSEESTTVHSSPVA 1893
Query: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815
+ + SP S L + SSP Q P + SG S+ +SRT +
Sbjct: 1894 TATT---PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE---ESRTSHSST 1947
Query: 816 RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFES 875
+ S PP S + SSP + P S TS ++ E + + S
Sbjct: 1948 THTISSPPSTTSALVEEPTSYHSSPGSTATTHFP--DSSTTSGRSEESTAS-------HS 1998
Query: 876 SPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSS 935
S D P+R S +S +S+T P S S ++ P ++S + SS
Sbjct: 1999 SQDATGTIVLPAR---STTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 2055
Query: 936 PSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE---TPPRQSHS-- 990
P T S VS S SHS S T P+ TP HS
Sbjct: 2056 PRSPATTLSPASTTSSGVSEESTT--------SHSRPGSTHTTAFPDSTTTPGLSRHSTT 2107
Query: 991 -----GSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLS-LCAGVKSST- 1043
GS + T GPS + S + +L PGS + L G +S+T
Sbjct: 2108 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL---SPGSTTALSFGQESTTF 2164
Query: 1044 --PPGESYFGV--SSLQLKGQSQTSPDHRSDTSSPEVRQS--HSESPSLQSKS---QTSP 1094
PG ++ + S G + S S T SP S S SP LQ +S QT P
Sbjct: 2165 HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 2224
Query: 1095 KGGRSRSSSPVTELAS--------RSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYP 1146
+ S P T A RSP F AS SG S + + F S +
Sbjct: 2225 ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT-SGHSEKSTIFHSSPDASG 2283
Query: 1147 TVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTL 1206
T S++ S ES P + T P E+S F +
Sbjct: 2284 TTPSSAHSTTSG--RGESTTSRISPGSTEITTLP-------GSTTTPGLSEASTTFYSSP 2334
Query: 1207 RTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTS 1266
R+P S A + + S S V S G L E ST+
Sbjct: 2335 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG---------LSEESTT 2385
Query: 1267 NFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENS 1326
+ SSP E T S+ E + S H + ++ + S L E S
Sbjct: 2386 VYSSSPGSTETTVFPRT-----PTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES 2440
Query: 1327 FGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTR---SSGHSS 1383
P P T+ TG + T + D+ E+ST SSG +
Sbjct: 2441 TAFP-----GSPASTQ--TGLPA---------------TLTTADLGEESTTFPSSSGSTG 2478
Query: 1384 SELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGS 1443
+ LSP +G+ TPSR SS + + G P TPS +S +
Sbjct: 2479 TTLSPARSTTSGLVGES------------TPSRLSPSSTETTTLP-GSPTTPSLSEKSTT 2525
Query: 1444 ------------SPGLRDGSGTPSRHSLSGSSPG------MKDIPRTPSRGRSECDSSPE 1485
SP SG S S S PG D TP R S
Sbjct: 2526 FYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSS 2585
Query: 1486 PKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL 1545
P + T P S + S P + + T +++++ + GQ S + S
Sbjct: 2586 PGSTDTTLLPASTTTSGP--SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPG 2643
Query: 1546 DVKPSASPQERSES---DSSPDSKAKTRTPLRQRS-RSGSSPEVDSKSRLSPRRSRSGSS 1601
+ P + S ++S + T +P S S +SP + +S S +
Sbjct: 2644 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHT 2703
Query: 1602 PEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR--GPSPEGSSSTESSP 1659
AP +S + P + SG S K SP+ S +T SS
Sbjct: 2704 TPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 2763
Query: 1660 EHPPKSRTARRGSRSSP------------------EPKTKSRTPPRRRSSRSSPELTRKA 1701
R SR SP E T + PR ++ SP
Sbjct: 2764 HSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL 2823
Query: 1702 RLSRRSRSASSSP-ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRG 1760
+ S ++ S P T S P +P +S S S + PR+ TTS RG
Sbjct: 2824 GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRG 2883
Query: 1761 RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS----------------------SQSTS 1798
P+ + + E + T+ + S + +ST+
Sbjct: 2884 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 2943
Query: 1799 RRRQRSRSRSRVTRRRRGGSGYHSRS-PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857
+ + ++ R SG S P+R S T + G TP S K + TS
Sbjct: 2944 FPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS 3003
Query: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS-------------PVSRRRSRSRT 1904
P + S A+ + S + S+ S T+ P + S+ T
Sbjct: 3004 PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGST 3063
Query: 1905 SVTRRRSRSRASPVSRRRSRSRTPP------------VTRRRSRSRTPTTRRRSRSRTP- 1951
T + AS + ++ + + P +T + TPT T
Sbjct: 3064 EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 3123
Query: 1952 -PVTRRRSRSRTPPVTRRR--SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS 2008
P + + + T + S S T+P + + T SR ++P T + S
Sbjct: 3124 TPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS 3183
Query: 2009 RTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS-------RSPLAIRRRSRSRTPRT 2061
T + + + P + T L P + + S SP+ S T T
Sbjct: 3184 TTLGRSEESTTVHSSPGA-----TGTALFPTRSATSVLVGEPTTSPI-----SSGSTETT 3233
Query: 2062 ARGKRSLTRSPPAIRRRSASGSSSDRSRSAT-PPATRNHSG----SRTPPVALNSSRMSC 2116
A + T + +S + SS RS T PA+ SG S T S+ +
Sbjct: 3234 ALPGSTTTAG---LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTA 3290
Query: 2117 F----SRPSMSPTPLDRCRSPGMLEP-LGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTS 2171
F + P +S SPG + L T S L + GPG + T
Sbjct: 3291 FPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGST----ETTL 3346
Query: 2172 VPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQ-------------VPAP---- 2214
+P+N S + A T + T P ++S AG R + PAP
Sbjct: 3347 LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTT 3406
Query: 2215 ---VPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271
V L + ++ + +AS+ + + T + V A + +PA + L
Sbjct: 3407 SAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 3466
Query: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA---------- 2321
T S + P + + G + + ++ + T S P T +
Sbjct: 3467 EESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH 3526
Query: 2322 NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLT 2381
+ P S+ T P S+ G RS +TA + + T + PA T++ L G + T
Sbjct: 3527 SSPGSTATTHFPDSSTTSG-RSEESTAS-HSSQDATGTIVLPARSTTS----VLLGESTT 3580
Query: 2382 SPRVPLSAYERVS---GRTSPPLLDRARS-----RTPPSAPSQSRMTSERAPSPSSRMGQ 2433
SP + + E + T+P L +++ + R+P + S + TS S+
Sbjct: 3581 SP-ISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHS 3639
Query: 2434 APSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTT----PVAGSQSLSSGAVATTTSSAGD 2489
P + D +P S S S T P + + S SS T+ SS+G
Sbjct: 3640 RPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGS 3699
Query: 2490 HNGMLSVPAPGVPHS-DVGEPPASTGAQQPSALAALQPAKERRS----SSSSSSSSSSSS 2544
+ LS PG + G+ + + S L P S +S+ SS+ S
Sbjct: 3700 TDTALS---PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 3756
Query: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604
++ S +SS+S G + + P + T +E+ R P TP
Sbjct: 3757 RTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 3816
Query: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP-KPA 2663
SS++S S S+ SS +S ++ SS+ S++S S++S SP LP
Sbjct: 3817 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 3876
Query: 2664 SPKKPPPGERRSRSPRKPIDSL--------------RDSRSLSYSPVERRRPSPQPSPRD 2709
+P SPR P +L SRS S P+ +P
Sbjct: 3877 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 3936
Query: 2710 QQSSSSERGSRRGQRGDS---RSPSHKRRRETPSPRPMRHRSSRS 2751
+ S++ S G + RS + RRE P+ R S+ +
Sbjct: 3937 SEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHT 3981
Score = 216 bits (549), Expect = 3e-55
Identities = 604/2727 (22%), Positives = 914/2727 (33%), Gaps = 390/2727 (14%)
Query: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
R R+ +PA R+TS+ + S TS SR THT A + P G
Sbjct: 288 RSPDRTLSPA-------RTTSSGVSEKSTTSHSRP----GPTHTIAFPDSTTMP--GVSQ 334
Query: 305 EGDAPFSEPGTTSTQ------RPSS--PETATKQPSSPYEDKDK--DKKEKSATRPSPSP 354
E A S PG+T T PSS PE+ T S Y + D S + +P
Sbjct: 335 ESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTP 394
Query: 355 ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASP------TRDRSPPKS 408
SSTG +P + H G P + P S++ PS + T S P S
Sbjct: 395 VHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSS 454
Query: 409 PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA-PAPGSHREISSSPTSKNRSHGRA 467
S+SS + S + T V ++ +P PA A H E S T+ +RS G
Sbjct: 455 TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEES---TAYHRSPGST 511
Query: 468 KRDKSHSHTPSRRMGRSRSPAT--AKRGRSRSRTPTKRG-------HSRSRSPQWRRSRS 518
+ H S G S AT ++S TP+ HS S + R
Sbjct: 512 QT--MHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRD 569
Query: 519 AQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP 578
+ RS + + SP + + G + S G S TP
Sbjct: 570 SSTIS-GRSEESKASHSSPD----AMATTVLPAGSTPSVLVGDS--------------TP 610
Query: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSR 638
+ T A S ++ +S + + R + PA S S S SR
Sbjct: 611 SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 670
Query: 639 SPARRSGRSRSRTPARRGRSRSRT-------PARRGRSRSRTPARRSGRSRSRTPARRGR 691
P + + G S+ T P S T A G + +R G
Sbjct: 671 -PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGS 729
Query: 692 SRSRTPRRGRSRSRSLVRRGRSHS--RTPQRRGRSGSSSERKNKSRTSQRRSRSNSS--- 746
+ + + S L HS R+P S+ R+ +S T S +
Sbjct: 730 TETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPA 789
Query: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG---------SSPCPKQKSQTPPRRS 797
P S + S SP S + +S R + SG SSP Q P +
Sbjct: 790 PPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT 849
Query: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857
SG + S + + SS+ P S + SSP + P S TS
Sbjct: 850 TSGRGEESTTSHSSTTHTISSA---PSTTSALVEEPTSYHSSPGSTATTHFP--DSSTTS 904
Query: 858 PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP 917
++ E + + SS D P+R S +S +S+T P S S ++ P
Sbjct: 905 GRSEESTAS-------HSSQDATGTIVLPAR---STTSVLLGESTTSPISSGSMETTALP 954
Query: 918 KVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDT 977
+RS + SSP T S VS S SR P +H+ ++ PD+
Sbjct: 955 GSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTT-SRSRPGSTHT-TAFPDS 1012
Query: 978 KVKP----ETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSL 1033
P + S GS + T GPS + S + +L PGS
Sbjct: 1013 TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTAL---SPGST 1069
Query: 1034 S-LCAGVKSST---PPGESYFGV--SSLQLKGQSQTSPDHRSDTSSPEVRQS--HSESPS 1085
+ L G +S+T PG ++ + S G + S S T SP S S SP
Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 1129
Query: 1086 LQSKS---QTSPKGGRSRSSSPVTELAS--------RSPIRQDRGEFSASPMLKSGMSPE 1134
LQ +S QT P + S P T A RSP F AS SG S +
Sbjct: 1130 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT-SGHSEK 1188
Query: 1135 QSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQD 1194
+ F S + T S++ S ES P + T P
Sbjct: 1189 STIFHSSPDASGTTPSSAHSTTSG--RGESTTSRISPGSTEITTLP-------GSTTTPG 1239
Query: 1195 RPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILS 1254
E+S F + R+P S A + + S S V S G
Sbjct: 1240 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG---- 1295
Query: 1255 HLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEH 1314
L E ST+ + SS R + T+ + S+ E + S H +
Sbjct: 1296 -----LSEESTTVYSSS-----RGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFT 1345
Query: 1315 KELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQ 1374
++ + S L E S P P T+ TG + T + D+ E+
Sbjct: 1346 EDSTTSGLTEESTAFP-----GSPASTQ--TGLPA---------------TLTTADLGEE 1383
Query: 1375 STR---SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL 1431
ST SSG + ++LSP +G+ TPSR SS + + G
Sbjct: 1384 STTFPSSSGSTGTKLSPARSTTSGLVGES------------TPSRLSPSSTETTTLP-GS 1430
Query: 1432 PRTPSRRSRSGS------------SPGLRDGSGTPSRHSLSGSSPGM------------K 1467
P TPS +S + SP SG S S S PG
Sbjct: 1431 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS 1490
Query: 1468 DIPRTP-----SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESS 1522
D+ + P S+G +E SP + + SSP L P + + +
Sbjct: 1491 DLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP--DDTITSGL 1548
Query: 1523 VDQKTVARTPLGQ-----RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRS 1577
V+ T + G S +S L + + S SD++P T P+ +
Sbjct: 1549 VEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVST 1608
Query: 1578 RSGSSPEVDSKSRLSPRRSRSGSSPE------------------------VKDKPRAAPR 1613
S P + S + G S E + +P +P
Sbjct: 1609 TYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI 1668
Query: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGP----SPEGSSST----ESSPEHP-PK 1664
+ ++++ P + L +S + SS R P SP ++S+ ES+ H P
Sbjct: 1669 SSGSTETTALPGSTTTAGLSEKSTTFYSSP-RSPDTTLSPASTTSSGVSEESTTSHSRPG 1727
Query: 1665 SR--TARRGSRSSP---EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
S TA GS + P + T S + P + SP T + L S + SSP +
Sbjct: 1728 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTET 1787
Query: 1720 T-----------------------PPRHRRSPSVSSPEPAE----KSRSSRRRRSASSPR 1752
T P SP+ S+ E +S S + + P
Sbjct: 1788 TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPT 1847
Query: 1753 T-------KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR 1805
T TTS S +P S + R E++ T S + S
Sbjct: 1848 TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVH-------SSPVATATTPSP 1900
Query: 1806 SRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR 1865
+RS + + YHS + Q S GRS TS + S P S
Sbjct: 1901 ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 1960
Query: 1866 SRASPATHRRSRSRT-----PLISRRRSRSRTSPVSRRR----------SRSRTSVTRRR 1910
P ++ S T P S RS S S +RS TSV
Sbjct: 1961 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLL-- 2018
Query: 1911 SRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970
S SP+S + P + +T S R+P T + + + V+ +
Sbjct: 2019 GESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEEST 2078
Query: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS 2030
S + P + + S T SR T T S T S + + P+ +
Sbjct: 2079 TSHSRPGSTHTTAFPDSTTTPGLSRHST---TSHSSPGSTDTTLLPASTTTSGPSQESTT 2135
Query: 2031 RSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPA------IRRRSASGSS 2084
+P S A+ S T ++ G T P + + + SS
Sbjct: 2136 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS 2195
Query: 2085 SDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPT---PLDRC----RSPGMLE 2137
+ R+ PA+ G + A + S + PS T P++ RSPG
Sbjct: 2196 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 2255
Query: 2138 ----PLGSSRTPMSVLQQAGGSMMDGPGPRIPD-HQRTSVPENHAQSRIALALTAIS-LG 2191
P S+ + S S D G H TS SRI+ T I+ L
Sbjct: 2256 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2315
Query: 2192 TARPPPSMSAAGLAARMSQ-----VPAPVPLMSLRTAPAANLASRIPAASAAAMNLASAR 2246
+ P +S A S +P + SL + + P ++ + ++ AS
Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2375
Query: 2247 TPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAAL 2306
TP + S +P + PRT ++V +P T + A T L
Sbjct: 2376 TPGLSEESTTVYSSSPGSTETT--VFPRTPT--TSVRGEEPTT-----FHSRPASTHTTL 2426
Query: 2307 AALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASL 2366
T SG + +P S + Q A L + + T L+PA
Sbjct: 2427 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARS 2486
Query: 2367 TSARMAPALSGANLT-----------SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPS 2415
T++ + + + L+ SP P + + + TSP R+P + S
Sbjct: 2487 TTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP--------RSPDATLS 2538
Query: 2416 QSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQT-TPVAGSQS 2474
+ TS SS P + D +P S S S T T + + +
Sbjct: 2539 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 2598
Query: 2475 LSSGAVATTTSSAGDHNGMLSVPAPGVPHS-DVGEPPASTGAQQPSALAALQPAKERRS- 2532
+SG +T+S + +PG + G+ + + S L P S
Sbjct: 2599 TTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSG 2658
Query: 2533 ---SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589
+S+ SS+ S ++ S +SS+S G + + P + T +E+
Sbjct: 2659 IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEES 2718
Query: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
R P TP SS++S S S+ SS +S ++ SS+ S++S S++S
Sbjct: 2719 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 2778
Query: 2650 SPAKPGPQALP-KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY-----SPVERRRPSP 2703
SP LP +P SPR P +L + S S R +P
Sbjct: 2779 SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 2838
Query: 2704 QPSPRDQQSSSSERGSRRGQRGDSRSP 2730
S S+++ S S SP
Sbjct: 2839 THSTVSPASTTTPGLSEESTTVYSSSP 2865
Score = 210 bits (535), Expect = 1e-53
Identities = 591/2647 (22%), Positives = 914/2647 (34%), Gaps = 445/2647 (16%)
Query: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR 219
+K P PP S E S++ +P SS+P SS
Sbjct: 1838 SKDTMPAPPTTTSAFVELSTTSHGSP----------------SSTPTTHFSASSTTL--- 1878
Query: 220 SESESKKRKHRSP-----TPKSKRKSKDKKRKRSRSTTPAPKSRRA-HRSTSADSASSSD 273
SE H SP TP R + + S + +P S + H S+ ++ S+
Sbjct: 1879 GRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE 1938
Query: 274 TSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR-PSSPETATKQPS 332
SR+ S ++ THT + PS S E + S PG+T+T P S T+ +
Sbjct: 1939 ESRT---SHSSTTHTIS---SPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 1992
Query: 333 SPYEDKDKDKKE---------------KSATRPSPSPERSSTGPEPPAPTPLLAERHGGS 377
S +D +S T P S +T TP L+E+
Sbjct: 1993 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK---- 2048
Query: 378 PQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL-----PQSSSSESSPPSPQPTKVSR 432
+T P +P + SP S S E P S+ + + P S +SR
Sbjct: 2049 -----STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSR 2103
Query: 433 HASSSPESPKPA-----PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP 487
H+++S SP PA + S T+ + S G S T + G+ +
Sbjct: 2104 HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTT 2163
Query: 488 ATAKRGRSRSRT------------PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSR 535
+ G + + + R HS + SP+ S ++ S SP +G S
Sbjct: 2164 FHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS-----STSPGLQGEST 2218
Query: 536 SPQ-RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594
+ Q P + + + + ++ RSP + + + ++ S
Sbjct: 2219 AFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 2278
Query: 595 RSRTPTRRRSRSRTPARRGRSR-SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPA 653
+ T S T + RG S SR T P + S A + S R+P
Sbjct: 2279 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 2338
Query: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS 713
S T G S T + G + S S + T G S + V
Sbjct: 2339 TTLSPASMTSLGVGEE-STTSRSQPGSTHSTV------SPASTTTPGLSEESTTVYSSSP 2391
Query: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK-SRISSRRSRSLSSPRSKAKSR 772
S R+ ++S R + T R S + + S S S + P S A ++
Sbjct: 2392 GSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ 2451
Query: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
L +L+ ++ ++ + P +G++ A+S T S TPSR
Sbjct: 2452 TGLPATLT-TADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGES-----------TPSR 2499
Query: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892
S SS+ T GS T+P +E+S T F +SP + +P+ + S
Sbjct: 2500 LSPSSTE--------TTTLPGSPTTPSLSEKSTT------FYTSPRSPDATLSPATTTSS 2545
Query: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
G S +SST Q S ++ P + +P HS +S SP + P + +
Sbjct: 2546 GVSE---ESSTSHSQPGSTHTTAFPD--STTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 2600
Query: 953 VSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGS 1012
P + SHS S DT + P + S + + T +
Sbjct: 2601 SGPSQESTT------SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 2654
Query: 1013 KSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTS 1072
S E S + V S GS SST PG L+G+S T H + T
Sbjct: 2655 TSSGIVEAS--TRVHSSTGSPRTTLSPASSTSPG----------LQGESTTFQTHPASTH 2702
Query: 1073 SPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMS 1132
+ S + +P +S + RS S+P T + S G S + S S
Sbjct: 2703 TTPSPPSTATAPVEESTTYH-----RSPGSTPTTHFPASSTTS---GHSEKSTIFHS--S 2752
Query: 1133 PEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPV 1192
P+ S + SS++ T SR+ S E LP +T +P
Sbjct: 2753 PDASG-TTPSSAHSTTSGRGESTTSRISPG-STEITTLP---GSTTTPGLS--------- 2798
Query: 1193 QDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQI 1252
E+S F + R+P S A + + S S V S G
Sbjct: 2799 ----EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG-- 2852
Query: 1253 LSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP 1312
L E ST+ + SSP E T+ + S+ E + S H +
Sbjct: 2853 -------LSEESTTVYSSSPGSTET-----TVFPRSTTTSVRGEEPTTFHSRPASTHTTL 2900
Query: 1313 EHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMK 1372
++ + S L E S P P T+ TG + T + D+
Sbjct: 2901 FTEDSTTSGLTEESTAFP-----GSPASTQ--TGLPA---------------TLTTADLG 2938
Query: 1373 EQSTR---SSGHSSSELSPDAVEKAGMS--------SNQSISSPVLDAVPRTPSRERSSS 1421
E+ST SSG + + LSP +G+ S S + L P TPS S+
Sbjct: 2939 EESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 2998
Query: 1422 A--SSPEMKDGL--PRTPS------RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR 1471
+SP D P T + S S S PG + P + SG S +
Sbjct: 2999 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLS--QEPTAS 3056
Query: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVART 1531
S+G +E SP + + SSP L P + + + V+ T +
Sbjct: 3057 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP--DDTITSGLVEASTPTHS 3114
Query: 1532 PLGQ-----RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD 1586
G S +S L + + S SD++P T P+ + S P
Sbjct: 3115 STGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSST 3174
Query: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
+ S + G R++ + P A P RS +
Sbjct: 3175 PTTHFSASSTTLG-------------RSEESTTVHSSPGATGTALFPTRSATSVLVGEPT 3221
Query: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRT---PPRRRSSRSSPELTRKARL 1703
SP S STE+ TA GS ++ KS T PR + SP T + +
Sbjct: 3222 TSPISSGSTET---------TALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV 3272
Query: 1704 SRRSRSASSSP-ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRS 1762
S S ++ S P T + P P VS A S SSP + T+ S
Sbjct: 3273 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTA----------SHSSPGSTDTTLSPGS 3322
Query: 1763 PSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
+ G + + S T TT D + +S S GS + +
Sbjct: 3323 TTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSST---------GSPHTT 3373
Query: 1823 RSPA----RQESSRTSSRRRRGRSRTPP----TSRKRSRSRTSPAPWKRSRSRASPATHR 1874
SPA RQ S T + TP TS S TS ++P TH
Sbjct: 3374 LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTS-----HGSPSSTPTTHF 3428
Query: 1875 RSRSRTPLISRRRSRSRTSPVSRRRS----RSRTS-VTRRRSRSRASPVSRRRSRSRTPP 1929
+ S T S + +SPV+ + RS TS + + +SP S +
Sbjct: 3429 SASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESD 3488
Query: 1930 VTRRR------SRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSR 1983
T R S S T T + S T + + + P + + S T RS
Sbjct: 3489 TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 3548
Query: 1984 SRTSPVTRRRS--------RSRTSPVTRRRSRSRTSPV------TRRRSRSRTPPAIRRR 2029
T+ + + + RS TS + S TSP+ T S T P + +
Sbjct: 3549 ESTASHSSQDATGTIVLPARSTTSVLL---GESTTSPISSGSMETTALPGSTTTPGLSEK 3605
Query: 2030 SRS--RTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSP-----PAIRRRSASG 2082
S + +P P S + S T + G T P P + R S +
Sbjct: 3606 STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTS 3665
Query: 2083 SSSDRSRSATP-PATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGS 2141
SS S T PA+ SGS S+ S S S T D SPG
Sbjct: 3666 HSSPGSTDTTLLPASTTTSGS---------SQESTTSHSSSGST--DTALSPG------- 3707
Query: 2142 SRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA 2201
S T +S Q++ + PG T P++ S I A T + T P ++S
Sbjct: 3708 STTALSFGQEST-TFHSSPGST----HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 3762
Query: 2202 AGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRT 2261
A + Q + + +T PA+ + P ++A A P + R+
Sbjct: 3763 ASSTSPGLQGEST----AFQTHPASTHTTPSPPSTATA-----------PVEESTTYHRS 3807
Query: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA 2321
P + + + T S + +P A SGT P++A
Sbjct: 3808 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDA---------------------SGTTPSSA 3846
Query: 2322 NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLT--SARMAPA--LSG 2377
+ +S R ++ + + P S T + GS T L+ AS T S+ +P LS
Sbjct: 3847 HSTTSGR---GESTTSRISPGSTEITT---LPGSTTTPGLSEASTTFYSSPRSPTTTLSP 3900
Query: 2378 ANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ 2437
A++TS V E + R+ P S P++ + ++ E SS G +
Sbjct: 3901 ASMTSLGV---GEESTTSRSQP---GSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETT 3954
Query: 2438 SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP 2497
R P+ F SR TT + S +SG +T+ G
Sbjct: 3955 VFPRSTTTSVRREEPTTF--HSRPASTHTT-LFTEDSTTSGLTEESTAFPGS-------- 4003
Query: 2498 APGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSS----- 2552
PAST P+ L +E + SSS S+ + S + S++S
Sbjct: 4004 ------------PASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGE 4051
Query: 2553 SSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612
S+ S S S +E ++LP P PS + R P+ T + SS S
Sbjct: 4052 STPSRLSPSSTETTTLPGSPTT-----PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE 4106
Query: 2613 SSSSSSSSSSSS-------SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665
SS+S S S+ S+++S S ++S SS S+ ++ SP +L + ++
Sbjct: 4107 ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166
Query: 2666 KKPPPGE 2672
PG+
Sbjct: 4167 FHSSPGD 4173
Score = 207 bits (526), Expect = 2e-52
Identities = 560/2550 (21%), Positives = 894/2550 (35%), Gaps = 313/2550 (12%)
Query: 249 RSTT--PAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG 306
+STT +P+S A S + ++S S S S THTTA + +P R
Sbjct: 2522 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHST- 2580
Query: 307 DAPFSEPGTTSTQR-PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA 365
S PG+T T P+S T T PS + +T SP + T P +
Sbjct: 2581 -TSHSSPGSTDTTLLPAS--TTTSGPS------------QESTTSHSSPGSTDTALSPGS 2625
Query: 366 PTPLLAERHG----GSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESS 421
T L + SP TT + + TR S SP +SS S
Sbjct: 2626 TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 2685
Query: 422 PPSPQPTKVSRHASSSPESPKP-----APAPGS---HREISSSPTSKNRSHGRAKRDKSH 473
+ T H +S+ +P P AP S HR S+PT+ H A S
Sbjct: 2686 GLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT----HFPASSTTS- 2740
Query: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR 533
H+ + S A+ S T + RG S + + G + +P
Sbjct: 2741 GHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA 2800
Query: 534 S-------RSPQR---PGWSRSRNTQRRGRSRSARRGRSHSR-SPATRGRSRSRTPARRG 582
S RSP P S + ++ G +HS SPA+ + TP G
Sbjct: 2801 STTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS-----TTTP---G 2852
Query: 583 RSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPAR 642
S T S T T RS T + RG + +R S T + + + S
Sbjct: 2853 LSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPAS-THTTLFTEDSTTSGLT 2911
Query: 643 RSGRSRSRTPA--RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRG 700
+ +PA + G + T A G + P+ + +PAR S
Sbjct: 2912 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTS-------- 2963
Query: 701 RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSR 760
G TP R S + + S T+ S +++ S R
Sbjct: 2964 ----------GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT-----FYTSPRSPD 3008
Query: 761 SLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS 820
+ SP + S +S S S S P + P + SG SQ S + + ++ S
Sbjct: 3009 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLS 3068
Query: 821 PPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
P S + + SSP + P +ITS + T ++ P
Sbjct: 3069 PGSTTASSLGQQSTTFHSSPGDTETTLLP--DDTITSGLVEASTPTHSSTGSLHTTLTPA 3126
Query: 881 LKSRTP-SRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRS----HSGSSS 935
+ S + S P +TP SP +++ +V R S H +SS
Sbjct: 3127 SSTSAGLQEESTTFQSWPSSSDTTP---SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS 3183
Query: 936 PSPSRVTSRTTPRRSRSVS-----PCSNVESRLL--PRYSHSGSSSPDTKVKPETPPRQS 988
+ R TT S + P + S L+ P S S S +T P +
Sbjct: 3184 TTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAG 3243
Query: 989 HSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGES 1048
S + + + P +LS + + + + S PGS A S+T PG S
Sbjct: 3244 LSEKSTTF--YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVS 3301
Query: 1049 YFGVSSLQLKGQSQTSPDHRSDTSS---PEVRQSHSESPSLQSK--SQTSPKGGRSRSSS 1103
+S G + T+ S T+S PE HS S ++ + G +S+
Sbjct: 3302 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEAST 3361
Query: 1104 PVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAE 1163
PV ++ SP + SP + E + FQS +S T + + +E +
Sbjct: 3362 PVHS-STGSP------HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELST 3414
Query: 1164 SKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKD---TLRTPPRERSGAGSSP 1220
+ + +S P S + ES+ V T TP RS
Sbjct: 3415 TSH--------GSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 3466
Query: 1221 ETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAV 1280
E + P S+Q E S SH SS +S++ +S VEE +
Sbjct: 3467 EESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSH-SSTTHTISSAPSTTSALVEEPTSY 3525
Query: 1281 SLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLG 1340
S S P +++ G S E +S + P S LG
Sbjct: 3526 H------SSPGSTATTHFPDSSTTSGR---SEESTASHSSQDATGTIVLPARSTTSVLLG 3576
Query: 1341 TEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHS-SSELSPDAVEKAGMSSN 1399
+ SS E P T P L K + SS S ++ LSP + +G+S
Sbjct: 3577 ESTTSPISSGSMETTALPGST---TTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEE 3633
Query: 1400 QSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSL 1459
+ S SR S+ ++ P + S SSPG D + P+ +
Sbjct: 3634 STTSH----------SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 3683
Query: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS 1519
SGSS + S G ++ SP + + SSP + L P S
Sbjct: 3684 SGSS--QESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSG 3741
Query: 1520 --ESSVDQKTVARTPLGQRS-RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQR 1576
E+S + +P S S +S L + +A + + ++P + P+ +
Sbjct: 3742 IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES 3801
Query: 1577 SRSGSSPEVDSKSRLSPRRSRSGSSPE---VKDKPRAAPRAQSGSDSSPEPKAPAPRA-L 1632
+ SP + + SG S + P A+ S + S+ + + + +
Sbjct: 3802 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 3861
Query: 1633 PRRSRSGSSSKGRGPSP---EGSSSTESSPEHPPKSRT-ARRGSRSSPEPKTKSRTPPRR 1688
S ++ G +P E S++ SSP P + + A S E T SR+ P
Sbjct: 3862 SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 3921
Query: 1689 RSSRSSPELTRKARLSRRSRSA-SSSPET-------RSRTPPRHRRSPSVSSPEPAEKSR 1740
S SP T LS S + SSSP + RS T R P+ PA
Sbjct: 3922 THSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHT 3981
Query: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800
+ S +S T+ ++ SP+ GL + + + + TT SS ST +
Sbjct: 3982 TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF----PSSSGSTGTK 4037
Query: 1801 RQRSRSRSRVTRRRRGGSGYHSRS-PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPA 1859
+RS + SG S P+R S T + G TP S K + TSP
Sbjct: 4038 LSPARSTT---------SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 4088
Query: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS-------------PVSRRRSRSRTSV 1906
+ S A+ + S + S+ S T+ P + S+ T
Sbjct: 4089 SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEA 4148
Query: 1907 TRRRSRSRASPVSRRRSRSRTPP------------VTRRRSRSRTPTTRRRSRSRTP--P 1952
T + AS + ++ + + P +T + TPT T P
Sbjct: 4149 TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 4208
Query: 1953 VTRRRSRSRTPPVTRRR--SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRT 2010
+ + + T + S S T+P + T SR ++P T + S T
Sbjct: 4209 ASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTT 4268
Query: 2011 SPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS-------RSPLAIRRRSRSRTPRTAR 2063
+ + + P + T L P + + S SP+ S T TA
Sbjct: 4269 LGRSEESTTVHSSPGA-----TGTALFPTRSATSVLVGEPTTSPI-----SSGSTETTAL 4318
Query: 2064 GKRSLTRSPPAIRRRSASGSSSDRSRSAT-PPATRNHSG-------SRTPPVALNSSRM- 2114
+ T + +S + SS RS T PA+ SG S + P +++++
Sbjct: 4319 PGSTTTAG---LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFP 4375
Query: 2115 SCFSRPSMSPTPLDRCRSPGMLEP-LGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVP 2173
S + P +S SPG + L T S L + PG + T +P
Sbjct: 4376 SSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGST----ETTLLP 4431
Query: 2174 ENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQ-------------VPAP------ 2214
+N S + A T + T P ++S AG R + PAP
Sbjct: 4432 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA 4491
Query: 2215 -VPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASP 2273
V L + ++ + +AS+ + + T + V A + +PA + L
Sbjct: 4492 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 4551
Query: 2274 RTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA----------NY 2323
T S + P + + G + + ++ + T S P T + +
Sbjct: 4552 STTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS 4611
Query: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
P S+ T P S+ G RS +TA + + T + PA T++ L G + TSP
Sbjct: 4612 PGSTATTHFPDSSTTSG-RSEESTAS-HSSQDATGTIVLPARSTTS----VLLGESTTSP 4665
Query: 2384 RVPLSAYERVS--GRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS-SRMGQAPSQSLL 2440
+ + E + G T+ P L +S T S+PS + T A S + R ++ +
Sbjct: 4666 -ISSGSMETTALPGSTTTPGLSE-KSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSS 4723
Query: 2441 PPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG 2500
P A SP S S L+ ++T S + +S+A +
Sbjct: 4724 PVATATTPSPARSTTSG----LVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSS 4779
Query: 2501 VPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSS 2560
H+ + PP++T A +P S S +++ SS++S S S++ SS
Sbjct: 4780 TTHT-ISSPPSTTSA------LVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 4832
Query: 2561 SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620
D+ G TP P GR E T S ++ +S++++
Sbjct: 4833 PDTNGI----------------TPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPG 4876
Query: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
S+ S+ SSS S + S +S +SSS S
Sbjct: 4877 LSAKSTILYSSSRSPDQTLSPASMTSSSIS 4906
Score = 204 bits (518), Expect = 1e-51
Identities = 601/2736 (21%), Positives = 957/2736 (34%), Gaps = 453/2736 (16%)
Query: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASS-----------SDTSRSR 278
RSPT S STT + H + S S ++ S + S
Sbjct: 2335 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGST 2394
Query: 279 SRSAAAKTHTTALAGRSPSPASGRRGEGDAP-FSEPGTTS------TQRPSSPETATKQP 331
+ +T TT++ G P+ R F+E TTS T P SP A+ Q
Sbjct: 2395 ETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP--ASTQT 2452
Query: 332 SSPYEDKDKDKKEKSATRPSPSPERSST-GPEPPAPTPLLAERHGG--SPQPLATTPLSQ 388
P D E+S T PS S +T P + L+ E SP TT L
Sbjct: 2453 GLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPG 2512
Query: 389 EPVNPPSEASPTRDRSPPKSPEKL------------PQSSSSESSPPSPQPTK------- 429
P P T + P+SP+ +SS+S S P S T
Sbjct: 2513 SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTT 2572
Query: 430 --VSRHASSSPESPKPA-----PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMG 482
+SRH+++S SP PA + S T+ + S G S T + G
Sbjct: 2573 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFG 2632
Query: 483 RSRSPATAKRGRSRSRT------------PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQR 530
+ + + G + + + R HS + SP+ S ++ S SP
Sbjct: 2633 QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS-----STSPGL 2687
Query: 531 RGRSRSPQ-RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTP 589
+G S + Q P + + + + ++ RSP + + + ++
Sbjct: 2688 QGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 2747
Query: 590 ARRRSRSRTPTRRRSRSRTPARRGRSR-SRTPARRRSRTRSPVRRRSRSRSPARRSGRSR 648
S + T S T + RG S SR T P + S A + S
Sbjct: 2748 IFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS 2807
Query: 649 SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708
R+P S T G S T + G + S S + T G S + V
Sbjct: 2808 PRSPTTTLSPASMTSLGVGEE-STTSRSQPGSTHSTV------SPASTTTPGLSEESTTV 2860
Query: 709 RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK-SRISSRRSRSLSSPRS 767
S RS ++S R + T R S + + S S S + P S
Sbjct: 2861 YSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS 2920
Query: 768 KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKS 827
A ++ L +L+ ++ ++ + P +G++ A+S T S
Sbjct: 2921 PASTQTGLPATLT-TADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGES---------- 2969
Query: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS 887
TPSR S SS+ T GS T+P +E+S T F +SP + +P+
Sbjct: 2970 -TPSRLSPSSTE--------TTTLPGSPTTPSLSEKSTT------FYTSPRSPDATLSPA 3014
Query: 888 RHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP----SPSRVTS 943
+ SG S S + P + + + + SHS S SP T+
Sbjct: 3015 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTA 3074
Query: 944 RTTPRRSRSV-SPCSNVESRLLP------------RYSHSGSSSPDTKVKPETPPR---Q 987
+ ++S + S + E+ LLP +HS + S T + P + Q
Sbjct: 3075 SSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQ 3134
Query: 988 SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGE 1047
S + +P TP P + + P E S + S P SSTP
Sbjct: 3135 EESTTFQSWPSSSDTTPSPPGTTAA----PVEVS--TTYHSRP----------SSTPT-- 3176
Query: 1048 SYFGVSSLQLKGQSQTSPDHRSD-TSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVT 1106
++F SS L +++ H S + + + S + L + TSP S ++ +
Sbjct: 3177 THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 3236
Query: 1107 ELASRSPIRQDRGEFSASPM-----------LKSGMSPEQSRFQSDSSSYPTV---DSNS 1152
+ + + + F +SP SG+S E + S S T S +
Sbjct: 3237 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTT 3296
Query: 1153 LLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRE 1212
+ G S+ TA P D T SP S PES+
Sbjct: 3297 MPGVSQESTASHSS----PGSTDTTLSPG------STTASSLGPESTTF----------- 3335
Query: 1213 RSGAGSSPETKEQNSALPTSSQDEELMEV---VEKSEEPAGQILSHLSSELKEMSTSNFE 1269
SG GS+ T LP ++ L+E V S LS S ++ ++ F+
Sbjct: 3336 HSGPGSTETT-----LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 3390
Query: 1270 SSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGS 1329
S P ++ T + + S + PS + HFS L S S
Sbjct: 3391 SWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPT---THFSASSTTLGRSEESTTVHSS 3447
Query: 1330 PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQL----ETDPSLDMKEQSTRSSGHSSSE 1385
P+ + +G E + P Q E+D + E+ST S HSS+
Sbjct: 3448 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTS--HSSTT 3505
Query: 1386 LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR-SGSS 1444
+ +SS S +S +++ P+ SS S+ T S RS S +S
Sbjct: 3506 HT--------ISSAPSTTSALVEE----PTSYHSSPGSTATTHFPDSSTTSGRSEESTAS 3553
Query: 1445 PGLRDGSGTPSRHSLSGSSPGMKDIPRTP-SRGRSECDSSPEPKALPQTPRPRSRSPSSP 1503
+D +GT + S +S + + +P S G E + P P + SSP
Sbjct: 3554 HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSP 3613
Query: 1504 ELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSP 1563
L+P S + S V +++ SR GS+ + + P
Sbjct: 3614 RSPATTLSPA---STTSSGVSEESTT-----SHSRPGSTH---------------TTAFP 3650
Query: 1564 DSKAKTRTP--LRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGS-DS 1620
DS T TP R + S SSP + L + SGSS E + SGS D+
Sbjct: 3651 DS---TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQE-----STTSHSSSGSTDT 3702
Query: 1621 SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR---SSPE 1677
+ P + + + S + SS G S+ T P+ S +R S+
Sbjct: 3703 ALSPGSTTALSFGQESTTFHSSPG-------STHTTLFPDSTTSSGIVEASTRVHSSTGS 3755
Query: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737
P+T SP + L S + + P + TP SP ++ P E
Sbjct: 3756 PRTTL-----------SPASSTSPGLQGESTAFQTHPASTHTTP-----SPPSTATAPVE 3799
Query: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR-DRSGSSQS 1796
+S TT R +P S + EK+ D SG++ S
Sbjct: 3800 ES---------------TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 3844
Query: 1797 TSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT 1856
++ R S +R G T G + TP S + +
Sbjct: 3845 SAHSTTSGRGESTTSRISPGS---------------TEITTLPGSTTTPGLSEASTTFYS 3889
Query: 1857 SPAPWKRSRSRASPATHRRSRSRTPL-ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA 1915
SP SP T S T L + + SR+ P S + S S T +
Sbjct: 3890 SPR---------SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 3940
Query: 1916 SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTS 1975
+ V S +P T R+ TT R R P T SR + T S TS
Sbjct: 3941 TTVY-----SSSPGSTETTVFPRSTTTSVR---REEPTTFH-SRPASTHTTLFTEDSTTS 3991
Query: 1976 PITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTP 2035
+T + SP + + T S T P + + ++ PA RS T
Sbjct: 3992 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPA-----RSTTS 4046
Query: 2036 LLPRKRSRSR-SPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT-P 2093
L + + SR SP + + +P T P++ +S + +S RS AT
Sbjct: 4047 GLVGESTPSRLSPSSTETTTLPGSPTT-----------PSLSEKSTTFYTSPRSPDATLS 4095
Query: 2094 PATRNHSG----SRTPPVALNSSRMSCF----SRPSMSPTPLDRCRSPGMLEP-LGSSRT 2144
PAT SG S T S+ + F + +S P S G E L T
Sbjct: 4096 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGST 4155
Query: 2145 PMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAI-----SLGTARPPPSM 2199
S L Q + PG D + T +P++ S + A T SL T P S
Sbjct: 4156 TASSLGQQSTTFHSSPG----DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS 4211
Query: 2200 SAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTP-----AIPTAV 2254
++ GL + + S T P+ + +P + + + TP A T +
Sbjct: 4212 TSTGLQEESTTFQSWPS--SSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL 4269
Query: 2255 NLADSRTPAAAAAMNLASPRTAVAP--SAVNLADPRTPTAPAVNLAGARTPAALAALSLT 2312
++ T ++ + TA+ P SA ++ T+P ++ T S T
Sbjct: 4270 GRSEESTTVHSSP---GATGTALFPTRSATSVLVGEPTTSP---ISSGSTETTALPGSTT 4323
Query: 2313 GSGTPPTAANYPSSSRTPQ---APASANLVG-----------PRSAHATA------PVNI 2352
+G + + SS R+P +PAS G P S H TA +
Sbjct: 4324 TAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGV 4383
Query: 2353 AGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDR-------A 2405
+ TA+ +P S T ++P + A+ P + + G T LL
Sbjct: 4384 SQESTASHSSPGS-TDTTLSPGSTTASSLGPES--TTFHSSPGSTETTLLPDNTTASGLL 4440
Query: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD-------------------- 2445
+ TP + + S T+ ++R G++ + P ++D
Sbjct: 4441 EASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSH 4500
Query: 2446 -QPRSPVPSAFSDQSRCL-------------IAQTTPVAGSQSLSSGAVATTTSSAGDHN 2491
P S + FS S L +A T + ++S +SG V +T+ H+
Sbjct: 4501 GSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTY---HS 4557
Query: 2492 GMLSVPAPGVPHSDV----GEPPAS-------TGAQQPSALAAL--QPAKERRSSSSSSS 2538
S P S+ GE + T + PS +AL +P S S+++
Sbjct: 4558 SPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT 4617
Query: 2539 SSSSSSSSSSSSSSSSSSGSSSSDSEGSS-LPVQPEVALKRVPSPTPAPKEAVRE--GRP 2595
+ SS++S S S++ SS D+ G+ LP + ++ S T E P
Sbjct: 4618 THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 4677
Query: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
T +S++ SS SS+ ++ S+SS++ S S++ SS +++++PSPA+
Sbjct: 4678 GSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST 4737
Query: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
L + ++ PG +++ P S RS SP S+
Sbjct: 4738 TSGLVEESTAYHSSPGS--TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 4795
Query: 2716 ERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
E + S + +H T S R +S S
Sbjct: 4796 EEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHS 4831
Score = 186 bits (473), Expect = 2e-46
Identities = 508/2248 (22%), Positives = 789/2248 (35%), Gaps = 372/2248 (16%)
Query: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807
E K S I+S + + P S + LS + + SSP ++ +P R + SG S+
Sbjct: 251 EPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTT 310
Query: 808 SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTP 867
S + P + + + P S T S S++ H P + SP S
Sbjct: 311 SHSRPGPTHTIAFP----DSTTMPGVSQESTASH-----SIPGSTDTTLSPGTTTPSSLG 361
Query: 868 QRRSCFESSPDPELKSRTPSRHSCSG---SSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS 924
+ F SSP +R P + SG +S P S+ P + S SSS + +
Sbjct: 362 PESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTF 421
Query: 925 PRQRSHSGSSSPSPSRVTS-----RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSP---D 976
S S +SP+PS TS TT S S +P ++ S HS S+P
Sbjct: 422 QSWPS-SKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHF-SASSTTLGHSEESTPVHSS 479
Query: 977 TKVKPETPP--RQSHSGSI--------SPYPKVKAQTPPGPSLSG-SKSPCPQEKSKDSL 1025
TPP R + SG + SP P + SG S+ S
Sbjct: 480 PVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT 539
Query: 1026 VQSCPGSLSLCA--GVKSSTPPGESYFGVSSLQLKGQSQTSPDHRS--DTSSPEVRQSHS 1081
S P + + A SS E+ S + G+S+ S S D + V + S
Sbjct: 540 KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGS 599
Query: 1082 ESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASP-----------MLKSG 1130
L S SP S ++ + ++ + + F +SP M SG
Sbjct: 600 TPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSG 659
Query: 1131 MSPEQSRFQSDSSSYPTV---DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK--- 1184
+S E + S S T S ++ G S+ TA P D T SP
Sbjct: 660 VSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS----PGPTDTTLSPGSTTASS 715
Query: 1185 --DKFSPFPVQDRP------------------ESSLVFKDTLRTPPRERSGAGSS----- 1219
+++ F RP E+S+ + R+P S AGS+
Sbjct: 716 LGPEYTTF--HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGE 773
Query: 1220 -------PETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSN--FES 1270
P +K+ A PT++ VE S G S ++ + ST++ E
Sbjct: 774 STTFHSWPSSKDTRPAPPTTTS-----AFVEPSTTSHGSPSSIPTTHISARSTTSGLVEE 828
Query: 1271 SPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSP 1330
S P + T+ +S + E + + H S H +S++P ++
Sbjct: 829 STTYHSSPGSTQTMHFPESDTTSGRGEESTTS------HSSTTH-TISSAPSTTSALVEE 881
Query: 1331 LEFRNSGPLGTEMNTGF--------------SSEVKEDLNGPFLNQLETDPSLDMKEQST 1376
+S P G+ T F +S +D G + + S+ + E +T
Sbjct: 882 PTSYHSSP-GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 940
Query: 1377 R--SSGHSSSELSPDAVEKAGMSSNQSI--SSPVLDAVPRTPSRERSSSASSPEMKDGLP 1432
SSG + P + G+S + SSP A +P+ SS S
Sbjct: 941 SPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSE-------- 992
Query: 1433 RTPSRRSRSGS--SPGLRDGSGTP--SRHS-LSGSSPGMKDIPRTP-------------- 1473
+ + RSR GS + D + TP SRHS S SSPG D P
Sbjct: 993 ESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTT 1052
Query: 1474 ---SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR 1530
S G ++ SP + + S+P + L P + + S V+ T
Sbjct: 1053 SHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFP--DSTTSSGIVEASTRVH 1110
Query: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
+ G + L S SP + ES + A T T S + + E +
Sbjct: 1111 SSTGSPRTT-----LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 1165
Query: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSD----SSPEPKAPAPRALPRRSRSGSSSKGRG 1646
SP GS+P + S SSP+ P S + S++ GRG
Sbjct: 1166 RSP-----GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP------SSAHSTTSGRG 1214
Query: 1647 PS------------------------PEGSSSTESSPEHPPKSRT-ARRGSRSSPEPKTK 1681
S E S++ SSP P + + A S E T
Sbjct: 1215 ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT 1274
Query: 1682 SRTPPRRRSSRSSPELTRKARLSRRS----RSASSSPET----RSRTPPRHRRSPSVSSP 1733
SR+ P S SP T LS S S+ S ET S T H P+
Sbjct: 1275 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHS 1334
Query: 1734 EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793
PA + S +S T+ ++ SP+ GL + + + + TT S
Sbjct: 1335 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT----FPSS 1390
Query: 1794 SQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS-PARQESSRTSSRRRRGRSRTPPTSRKRS 1852
S ST + +RS + SG S P+R S T + G TP S K +
Sbjct: 1391 SGSTGTKLSPARSTT---------SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 1441
Query: 1853 RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS-------------PVSRRR 1899
TSP + S A+ + S + S+ S T+ P +
Sbjct: 1442 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS 1501
Query: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTPP------------VTRRRSRSRTPTTRRRSR 1947
S+ T T + AS + ++ + + P +T + TPT
Sbjct: 1502 SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 1561
Query: 1948 SRT--PPVTRRRSRSRTPPVTRRR--SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTR 2003
T P + + + T + S S T+P + + T SR ++P T
Sbjct: 1562 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1621
Query: 2004 RRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS-------RSPLAIRRRSRS 2056
+ S T + + + P + T L P + + S SP+ S
Sbjct: 1622 FSASSTTLGRSEESTTVHSSP-----GATGTALFPTRSATSVLVGEPTTSPI-----SSG 1671
Query: 2057 RTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT-PPATRNHSG----SRTPPVALNS 2111
T TA + T + +S + SS RS T PA+ SG S T S
Sbjct: 1672 STETTALPGSTTT---AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS 1728
Query: 2112 SRMSCF----SRPSMSPTPLDRCRSPGMLE-PLGSSRTPMSVLQQAGGSMMDGPGPRIPD 2166
+ + F + P +S SPG + L T S L + PG
Sbjct: 1729 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG----S 1784
Query: 2167 HQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQ-------------VPA 2213
+ T +P+N S + A T + T P ++S AG R + +PA
Sbjct: 1785 TETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPA 1844
Query: 2214 P-------VPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAA 2266
P V L + ++ + +AS+ + + T + V A + +PA +
Sbjct: 1845 PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST 1904
Query: 2267 AMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA----- 2321
L TA S + P + + + + ++ + T S P T +
Sbjct: 1905 TSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE 1964
Query: 2322 -----NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALS 2376
+ P S+ T P S+ G RS +TA + + T + PA T++ L
Sbjct: 1965 PTSYHSSPGSTATTHFPDSSTTSG-RSEESTAS-HSSQDATGTIVLPARSTTS----VLL 2018
Query: 2377 GANLTSPRVPLSAYERVS--GRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQA 2434
G + TSP + + E + G T+ P L +S T S+P T A + SS + +
Sbjct: 2019 GESTTSP-ISSGSMETTALPGSTTTPGLSE-KSTTFHSSPRSPATTLSPASTTSSGVSEE 2076
Query: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA----------VATTT 2484
+ S +P S +AF D + TTP S +S + A+TT
Sbjct: 2077 STTS-----HSRPGSTHTTAFPDST------TTPGLSRHSTTSHSSPGSTDTTLLPASTT 2125
Query: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGA---QQPSALAALQPAKERRSSSSSSSSSS 2541
+S S +PG +D P ST A Q S P + S++SS
Sbjct: 2126 TSGPSQESTTSHSSPG--STDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS 2183
Query: 2542 S--------SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV----PSPTPAP-KE 2588
SS+ S ++ S + S+S +G S Q A PS AP +E
Sbjct: 2184 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEE 2243
Query: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
+ R P TP SS++S S S+ SS +S ++ SS+ S++S S++S
Sbjct: 2244 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 2303
Query: 2649 PSPAKPGPQALP-KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY-----SPVERRRPS 2702
SP LP +P SPR P +L + S S R +P
Sbjct: 2304 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2363
Query: 2703 PQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
S S+++ S S SP
Sbjct: 2364 STHSTVSPASTTTPGLSEESTTVYSSSP 2391
Score = 174 bits (442), Expect = 8e-43
Identities = 577/2650 (21%), Positives = 914/2650 (34%), Gaps = 340/2650 (12%)
Query: 222 SESKKRKHRSPTPKSKRKSKDKKRKRS---RSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
S+ H SP S S STT H + DS +SS +
Sbjct: 2604 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 2663
Query: 279 SR--SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE 336
+R S+ TT S SP G +GE + P +T T PS P TAT +P E
Sbjct: 2664 TRVHSSTGSPRTTLSPASSTSP--GLQGESTTFQTHPASTHTT-PSPPSTAT----APVE 2716
Query: 337 DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396
+ + +T + P S+T T + SP TTP S
Sbjct: 2717 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS-----SPDASGTTPSSAHSTTSGRG 2771
Query: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE--IS 454
S T SP + + ++ S +P ++ S SSP SP +P S +
Sbjct: 2772 ESTTSRISPGST-----EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 2826
Query: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS---RSRSP 511
T+ G S + T + + + + S T R + R P
Sbjct: 2827 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEP 2886
Query: 512 QWRRSRSAQRWGR---SRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPA 568
SR A S S PG S T +A G + P+
Sbjct: 2887 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 2946
Query: 569 TRGRSRSR-TPARR---GRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS-RTPARR 623
+ G + + +PAR G TP+R S T TP+ +S + T R
Sbjct: 2947 SSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 3006
Query: 624 RSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRS 683
T SP S S S S S+ + + + G S+ T + S S
Sbjct: 3007 PDATLSPATTTSSGVS--EESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTE 3064
Query: 684 RTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRS 743
T + + S ++ + S G + + + E + +S +
Sbjct: 3065 ATLSPGSTTASSLGQQSTTFHSS---PGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 3121
Query: 744 NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ 803
+P S S + S S + + S G++ P + S T R S +
Sbjct: 3122 TLTPASSTSAGLQEESTTFQSWPSSSDTT----PSPPGTTAAPVEVSTTYHSRPSSTPTT 3177
Query: 804 PKAKSRTPPRRSRSS----SSPPPKQKSKTPSRQSHS------SSSPHPKVKSGTPPRQG 853
+ S T RS S SSP + P+R + S ++SP + T G
Sbjct: 3178 HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 3237
Query: 854 SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSS 913
S T+ +E+S T F SSP + +P+ + SG S S + P + + +
Sbjct: 3238 STTTAGLSEKSTT------FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 3291
Query: 914 SPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTT-----PRRSRSVSPCSNVESRLLPRYS 968
+ + SHS S + TT P + S + E+ LLP +
Sbjct: 3292 PGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNT 3351
Query: 969 ------------HSGSSSPDTKVKPE-TPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSP 1015
HS + SP T + P + RQ S + +P K TP P+ + +
Sbjct: 3352 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV- 3410
Query: 1016 CPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPE 1075
E S S P S SST G S + + T+P T+S
Sbjct: 3411 ---ELSTTS--HGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL 3465
Query: 1076 VRQS---HSESPSLQS-----KSQTSPKGGRSRSS-SPVTELASRSP-----IRQDRGEF 1121
V +S HS S Q+ TS +G S +S S T S +P + ++ +
Sbjct: 3466 VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY 3525
Query: 1122 SASP-----------MLKSGMSPEQSRFQSDSSSYPTV------DSNSLLGQSRLE--TA 1162
+SP SG S E + S + T+ ++ LLG+S ++
Sbjct: 3526 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 3585
Query: 1163 ESKEKMALPPQEDATASPPRQKDKFSPFPVQDR-PESSLVFKDTLRTPPRERSGAGSSPE 1221
S E ALP + + P +K + F R P ++L T + E S S
Sbjct: 3586 GSMETTALP----GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRP 3641
Query: 1222 TKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVS 1281
+A P S+ L S G + L S S+ ES+ +
Sbjct: 3642 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTD 3701
Query: 1282 LTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRE------NSFGSPLEFRN 1335
L + A E + SS G H + ++S + E +S GSP R
Sbjct: 3702 TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RT 3758
Query: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDP----SLDMKEQST--RSSGHSSSELSPD 1389
+ + + G E P P + ++E +T RS G + + P
Sbjct: 3759 TLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPA 3818
Query: 1390 AVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
+ +G S +I DA TPS S+++ E T SR S +
Sbjct: 3819 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES------TTSRISPGSTEITTLP 3872
Query: 1450 GSGTPSRHSLSGSSPGMKDIPRTPSR------------GRSECDSSPEPKALPQTPRPRS 1497
GS T LS +S PR+P+ G S +P + T P S
Sbjct: 3873 GSTTTP--GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS 3930
Query: 1498 RSPSSPELNNKCLTPQRERSGS-ESSVDQKTVART-----PLGQRSRSGSSQE-LDVKPS 1550
+ +P L+ + T GS E++V ++ + P SR S+ L + S
Sbjct: 3931 TT--TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDS 3988
Query: 1551 ASPQERSESDSSPDSKAKTRT---------PLRQRSRSGSSPEVDSKSRLSPRRSRSGSS 1601
+ ES + P S A T+T L + S + S + ++LSP RS +
Sbjct: 3989 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048
Query: 1602 PEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS-------RSGSSSKGRGPSPEGSSS 1654
R +P S ++++ P +P +L +S RS ++ + S
Sbjct: 4049 VGESTPSRLSP---SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 4105
Query: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRK------ARLSRRSR 1708
ESS H T S S+ P SS+ S E T + L ++S
Sbjct: 4106 EESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQST 4165
Query: 1709 SASSSPETRSRT--PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT----------- 1755
+ SSP T P S V + P S S + T T
Sbjct: 4166 TFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQS 4225
Query: 1756 -TSRRGRSPSPKPRGLQ----RSRSRSRREKTRTTRRRDRSG----SSQSTSRRRQRSRS 1806
S +PSP + SR T TT S S +ST+ +
Sbjct: 4226 WPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 4285
Query: 1807 RSRVTRRRRGGS---GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKR 1863
+ + R S G + SP S+ T++ G + T S K + +SP
Sbjct: 4286 GTALFPTRSATSVLVGEPTTSPISSGSTETTALP--GSTTTAGLSEKSTTFYSSPRSPDT 4343
Query: 1864 SRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923
+ S AS + S T SR S T+ S S + V++ + S +SP S +
Sbjct: 4344 TLSPASTTSSGVSEESTTSHSRPGSMHTTAFPS---STTMPGVSQESTASHSSPGSTDTT 4400
Query: 1924 RSRTPPVTRRRSRSRTPTTRRRSRSRTPPV------TRRRSRSRTPPVTRRRSRSRT--S 1975
S P T S TT S T T + PV T S
Sbjct: 4401 LS--PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 4458
Query: 1976 PI--TRRRSRSRT------SPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIR 2027
P T R+ S T S T + TS + S SP + +
Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 4518
Query: 2028 RRSRSRTPLLPRKRSRSRSPLAIRRRS-----RSRTPRTARGKRSLTRSPPAIRRRSASG 2082
RS T + + + +P R + S T ++ G P + S G
Sbjct: 4519 GRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES-NTTSGRG 4577
Query: 2083 SSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPL--DRCRSPGMLEPLG 2140
S S S+T T S + + AL S S P + T D + G E
Sbjct: 4578 EESTTSHSST---THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 4634
Query: 2141 SSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMS 2200
+S + Q A G+++ +P TSV + + +++ S+ T P S +
Sbjct: 4635 ASHSS----QDATGTIV------LPARSTTSVLLGESTTS---PISSGSMETTALPGSTT 4681
Query: 2201 AAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSR 2260
GL+ + + + ++P++ + +AS+ + + T + V A +
Sbjct: 4682 TPGLSEKST---------TFHSSPSSTPTTHF-SASSTTLGRSEESTTVHSSPVATATTP 4731
Query: 2261 TPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTA 2320
+PA + L TA S + P + + + + ++ + T S P T
Sbjct: 4732 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 4791
Query: 2321 A----------NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSAR 2370
+ + P S T P S+ G RS +TA + + L TS R
Sbjct: 4792 SALVEEPTSYHSSPGSIATTHFPESSTTSG-RSEESTASHSSPDTNGITPLPAHFTTSGR 4850
Query: 2371 MAPALSG-ANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER-APSPS 2428
+A + + + S L++ G ++ + + SR+P S + MTS + P+
Sbjct: 4851 IAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPT 4910
Query: 2429 SRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAG 2488
S QA S P S S S +S + P + +LS G++ TT+S A
Sbjct: 4911 SLYSQAESTHTTA----FPASTTTSGLSQESTTF--HSKPGSTETTLSPGSI-TTSSFAQ 4963
Query: 2489 DHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSS 2548
+ PHS G SAL+ + PA S S++ SS S+
Sbjct: 4964 EFT---------TPHSQPG-----------SALSTVSPASTTVPGLSEESTTFYSSPGST 5003
Query: 2549 SSSSSSSSGSSSSDSEGSS-LPVQPEVALKRVPSP----------------------TPA 2585
+++ S S + S S+ S+ P P +P+ TP
Sbjct: 5004 ETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPL 5063
Query: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
P + EPT S S + ++ +SSS+S + S++ +S S +S+ S
Sbjct: 5064 PARSTASDLVGEPTTFY----ISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVS 5119
Query: 2646 SSSPSPAKPG 2655
+ S PG
Sbjct: 5120 TESLETLAPG 5129
Score = 163 bits (412), Expect = 2e-39
Identities = 430/2009 (21%), Positives = 713/2009 (35%), Gaps = 264/2009 (13%)
Query: 797 SRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT 856
+ SG S+ S + P + ++ P S T +SP T GS T
Sbjct: 216 TNSGHSEESTVSHSGPGATGTTLFP---SHSATSVFVGEPKTSPITSASMETTALPGSTT 272
Query: 857 SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ 916
+ +E+S T F SSP ++ +P+R + SG S S + P + + +
Sbjct: 273 TAGLSEKSTT------FYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDS 326
Query: 917 PKVKAIISPRQRSHS-----------GSSSPS---PSRVTSRTTPRRSRSVS-PCSNVES 961
+ + SHS G+++PS P T ++P +++ P + S
Sbjct: 327 TTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTS 386
Query: 962 RLLPRYS--HSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE 1019
LL + HS + SP T + P + +H G + + + P+ SG+ S +
Sbjct: 387 GLLEASTPVHSSTGSPHTTLSPSS--STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVK- 443
Query: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS 1079
+ S P SSTP ++F SS L +++P H S +
Sbjct: 444 --LSTTYHSSP----------SSTP--TTHFSASSTTLGHSEESTPVHSSPVA------- 482
Query: 1080 HSESPSLQSKSQTSPKGGRSRSSSPVTELAS--RSPIRQDRGEFSASPMLKSGMSPEQSR 1137
+ T+P RS +S V E + RSP F S SG S E +
Sbjct: 483 ----------TATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPES-STTSGHSEESAT 531
Query: 1138 FQSDS----SSYPTVDS-------NSLLGQSRLETAESKEKMALPPQEDATASPPRQKDK 1186
F + SS P+ + +S LG + ET ++ + + + + + D
Sbjct: 532 FHGSTTHTKSSTPSTTAALAHTSYHSSLGST--ETTHFRDSSTISGRSEESKASHSSPDA 589
Query: 1187 FSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELME-VVEKS 1245
+ + S++ D+ TP SG+ + +ALP S+ L E
Sbjct: 590 MATTVLPAGSTPSVLVGDS--TPSPISSGS-------METTALPGSTTKPGLSEKSTTFY 640
Query: 1246 EEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSW 1305
P +HL + + S E S RP + + A + +P ++
Sbjct: 641 SSPRSPDTTHLPASMTSSGVS--EESTTSHSRPG------STHTTAFPGSTTMPGLSQES 692
Query: 1306 GGPHFSPEHKELSNSP--LRENSFGSPLEFRNSGPLGTEM-----NTGFSS------EVK 1352
H SP + + SP +S G +S P TE NT S V
Sbjct: 693 TASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVH 752
Query: 1353 EDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGM---SSNQSISSPVLDA 1409
P + E +T S SS + P S S SP +
Sbjct: 753 SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP--SS 810
Query: 1410 VPRTPSRERSSSASSPEMKDGLPRTP-SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD 1468
+P T RS+++ E +P S ++ G G S S S ++ +
Sbjct: 811 IPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS 870
Query: 1469 IPRTPSRGRSECDS-SPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527
P T S E S P + T P S + S + ++ +G+ + ++
Sbjct: 871 APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT-IVLPARS 929
Query: 1528 VARTPLGQRSR---SGSSQELDVKPSASP----QERSES-DSSPDSKAKTRTPLRQRSRS 1579
LG+ + S S E P ++ ERS + SSP S A T +P S
Sbjct: 930 TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSG 989
Query: 1580 GSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSG 1639
S S+SR P + + + P+ P ++ + S P + LP
Sbjct: 990 VSEESTTSRSR--PGSTHTTAFPDSTTTPGL---SRHSTTSHSSPGSTDTTLLP------ 1038
Query: 1640 SSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTR 1699
+S+ GPS E ++S SS + S + T + P + P+ T
Sbjct: 1039 ASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTT 1098
Query: 1700 KARLSRRS-RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT--- 1755
+ + S R SS+ R+ P SP + A ++ + + S P T T
Sbjct: 1099 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPV 1158
Query: 1756 --TSRRGRSPSPKPRGLQRSRSRSRREKTRTT---RRRDRSGSSQSTSRRRQRSRSRSRV 1810
++ RSP P + S + ++T D SG++ S++ R S
Sbjct: 1159 EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT 1218
Query: 1811 TRRRRGGSGY-----HSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRS- 1864
+R G + + +P E+S T R PT+ S TS + S
Sbjct: 1219 SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS-----PTTTLSPASMTSLGVGEEST 1273
Query: 1865 RSRASP-ATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923
SR+ P +TH S S T+P S + S +R + + P S S
Sbjct: 1274 TSRSQPGSTH----------STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTS 1323
Query: 1924 RSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSR 1983
P T + T TT S T +T + P + + T
Sbjct: 1324 VHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 1383
Query: 1984 SRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR 2043
S T P + + ++ SP +RS TS + + SR P S + T LP
Sbjct: 1384 STTFPSSSGSTGTKLSP-----ARSTTSGLVGESTPSRLSP-----SSTETTTLP----- 1428
Query: 2044 SRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSR 2103
SP +S T T+ T SP ++SG S + S S + P + + +
Sbjct: 1429 -GSPTTPSLSEKSTTFYTSPRSPDATLSPAT---TTSSGVSEESSTSHSQPGSTHTTAFP 1484
Query: 2104 TPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPR 2163
+ S+ S S T + SPG T S L Q + PG
Sbjct: 1485 DSTTTSDLSQEPTTSHSSQGST--EATLSPG--------STTASSLGQQSTTFHSSPG-- 1532
Query: 2164 IPDHQRTSVPENHAQSRIALALTAI-----SLGTARPPPSMSAAGLAARMSQVPAPVPLM 2218
D + T +P++ S + A T SL T P S ++AGL + +
Sbjct: 1533 --DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS 1590
Query: 2219 SLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVA 2278
+P A+ + ++ +S T + + + + TA+
Sbjct: 1591 DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALF 1650
Query: 2279 P--SAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQ---AP 2333
P SA ++ T+P ++ T S T +G + + SS R+P +P
Sbjct: 1651 PTRSATSVLVGEPTTSP---ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1707
Query: 2334 ASANLVG-----------PRSAHATA------PVNIAGSRTAAALAPASLTSARMAPALS 2376
AS G P S H TA ++ TA+ +P S T ++P +
Sbjct: 1708 ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS-TDTTLSPGST 1766
Query: 2377 GANLTSPRVPLSAYERVSGRTSPPLL-------DRARSRTPPSAPSQSRMTSERAPSPSS 2429
A+ P + + G T LL + TP + + S T+ ++
Sbjct: 1767 TASSLGPE--STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 1824
Query: 2430 RMGQAPSQSLLPPAQDQPRSP--VPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487
R G++ + P ++D +P SAF + S TT S + + ++++
Sbjct: 1825 RQGESTTFQSWPSSKDTMPAPPTTTSAFVELS------TTSHGSPSSTPTTHFSASSTTL 1878
Query: 2488 GDHNGMLSVPAPGVPHSDVGEPPAST--GAQQPSALAALQPAKERRSSSSSSSSSSSSSS 2545
G +V + V + P ST G + S P + SS++S S
Sbjct: 1879 GRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE 1938
Query: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA---PKEAVREGRPPEPTPAK 2602
S +S SS++ SS S S+L +P + P T P + GR E T +
Sbjct: 1939 ESRTSHSSTTHTISSPPSTTSALVEEP-TSYHSSPGSTATTHFPDSSTTSGRSEESTASH 1997
Query: 2603 RKR----------RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
+ RS++S S++S SS S +++ S+++ S S++ SP
Sbjct: 1998 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR 2057
Query: 2653 KPGPQALPKPASPKKPPPGERRSRSPRKP 2681
P PAS E + S +P
Sbjct: 2058 SPATTL--SPASTTSSGVSEESTTSHSRP 2084
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 223 bits (567), Expect = 3e-57
Identities = 573/2642 (21%), Positives = 932/2642 (35%), Gaps = 341/2642 (12%)
Query: 250 STTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTH-----------TTALAGRSPSP 298
STTPA + +TS++++SSS T+ S + + TT +A S
Sbjct: 591 STTPADSNTFV--TTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEAST 648
Query: 299 ASGRRGEGDAPFSEPGTTSTQRPSSPETA--TKQPSSPYEDKDKDKKEKSATRPSPSPER 356
S + + P TTST+ SS TA T P+S Y + +
Sbjct: 649 LSTTPVDSNTPV----TTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSE 704
Query: 357 SSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSS 416
+ST P T + T + P + PSE S T S P S L +
Sbjct: 705 ASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGS-TPLTSMPVSKTLL---T 760
Query: 417 SSESSPPSPQPTKVSRHASSSPE-SPKPAPAPGSHREISS----SPTSKNRSHGRAKRDK 471
SSE+S S P S H ++S E S P G+ IS+ SP +
Sbjct: 761 SSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS 820
Query: 472 SHSHTPSRRMGRSRSPATAKRGRSRSRTPTK------RGHSRSRSPQWRRSRSAQRWGRS 525
+ T S S SP T S S TP + +S R+P S S
Sbjct: 821 PEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATS 880
Query: 526 RSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR 585
S +P + +T+ R S S +T G + + +
Sbjct: 881 AISTL---STTPVDTSTPVTNSTEARS---SPTTSEGTSMPTSTPGEGSTPLTSMPDSTT 934
Query: 586 SRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG 645
+ R+ S TP + TP + +P T P S +P +
Sbjct: 935 PVVSSEARTLSATPVD----TSTPVTTSTEATSSPTTAEG-TSIPTSTPSEGTTPLTSTP 989
Query: 646 RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSR-SRTPRRGRSRS 704
S + + S TP S TP S + S P G S + TP G
Sbjct: 990 VSHTLVANSEASTLSTTPVD-----SNTPLTTSTEASSPPPTAEGTSMPTSTPSEGS--- 1041
Query: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSS 764
TP R ++ +++ T S+P S+ SS S + +
Sbjct: 1042 ------------TPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASS--SSTTAD 1087
Query: 765 PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS-------RS 817
S S S GS+P + P SS+ S TP S +
Sbjct: 1088 GTSMPTSTYS-----EGSTPL----TSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEA 1138
Query: 818 SSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSP 877
SSSP + + P+ ++P + P + S +AN S TP
Sbjct: 1139 SSSPTTAEGTSIPTSPPSEGTTP----LASMPVSTTLVVSSEANTLSTTP---------- 1184
Query: 878 DPELKSRTPSRHSCSGSSPPRVKSSTP-PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP 936
+ S+T S SSPP T P +P S+P + +P S + + S
Sbjct: 1185 ---VDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLST 1241
Query: 937 SPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996
SP ++ T S SP + E LP + S S+ T + T S S
Sbjct: 1242 SPVDTSTPVTTSAETSSSP-TTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLT 1300
Query: 997 PKVKAQTPPGPSLSGSKSPCPQEKSK---------DSLVQSCPGSLSLCAG----VKSST 1043
V + P S S SP P E + + + S P + +L A + S+T
Sbjct: 1301 TPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTT 1360
Query: 1044 PPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSS 1103
P S + + ++ +SP TS P S +P T+P S+
Sbjct: 1361 PVDNS----TPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTL 1416
Query: 1104 PVTELASRSPIRQDRGEFSASPMLKSGMS-----PEQSRF-------------QSDSSSY 1145
T + + +P E ++SP G+S P + + S++S+
Sbjct: 1417 SATPVDTSTP-GTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTL 1475
Query: 1146 PT--VDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFK 1203
T VDSNS + S TA S A ++P + PV +S
Sbjct: 1476 STTPVDSNSPVVTS---TAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEIN 1532
Query: 1204 DTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEM 1263
TP S+P T ++ ++ D M+ SE +S+ L
Sbjct: 1533 SLSTTP-----AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVS 1587
Query: 1264 STSNFESSPEVEERPAVSLTLDQSQS---QASLEAVEVPSMASSW-------GGPHFSPE 1313
S +N S+ ++ + V+ + + S S + S + PS S P SPE
Sbjct: 1588 SEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPE 1647
Query: 1314 HKELSNSPLRENSFGSPLEFRNSGPL---GTEMNTGFSSEVKEDLNG------------- 1357
LS +P+ NS +S P GT M T +E + L
Sbjct: 1648 ASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAI 1707
Query: 1358 ------PFLNQLETDPSLDMKEQSTRSSGHSSSELSPDA----VEKAGMSSNQSISSPV- 1406
P N S + + T S G S +P + +S+ +SS
Sbjct: 1708 STLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEAS 1767
Query: 1407 -LDAVP---RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGS 1462
L A P TP + + SSP +G S S G+ + TP H+L +
Sbjct: 1768 TLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSE-----GMTPLTSTPVSHTLVAN 1822
Query: 1463 SPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESS 1522
S + TP S +S + P S + S+P + LT + + +S
Sbjct: 1823 SEA-STLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVAS 1881
Query: 1523 VDQKTVARTPL---------GQRSRSGSSQELDVKPSASPQE----------------RS 1557
+ T++ TP Q S S ++ + P+++P+E S
Sbjct: 1882 SETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASS 1941
Query: 1558 ESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSG 1617
E ++ + A TRTP+ S++ SSP + + GS+P + P + S
Sbjct: 1942 EINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTP-LTSMPLSTTLVVS- 1999
Query: 1618 SDSSPEPKAPAPRALPRR-SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSP 1676
S++S P + P S GSSS +ST S P S
Sbjct: 2000 SEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSS 2059
Query: 1677 EPKTKSRTPPRRRSS-RSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735
E T S TP ++ +S E + A S + S+ E + V+SPE
Sbjct: 2060 EGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEA 2119
Query: 1736 AEKSRSSRRRRSASSPRTKTTSRRGRSPSP-KPRGLQRSRSRSRREK-----TRTTRRRD 1789
+ S + S T+ +S SP P + +Q S RR TT
Sbjct: 2120 STLSTTPVDSNSPVITSTEVSS----SPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVAS 2175
Query: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSR 1849
+ S+ ST+ + + R + + P S ++ S P +
Sbjct: 2176 SAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTS 2235
Query: 1850 KRSRSRTSPAPWKR-----SRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR-SRSR 1903
+ S +P + + +SP T + T +S + + PVS + S
Sbjct: 2236 EASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSE 2295
Query: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPV-------TRRRSRSRTPTTRRRSRSRTPPVTRR 1956
S +P + S PP T S TP TR +
Sbjct: 2296 VSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFET 2355
Query: 1957 RSRSRTP-----PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVT-------RR 2004
+ S TP PVT S++ +SP T + TS + + + PV+
Sbjct: 2356 STLSTTPADTSTPVTTY-SQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEA 2414
Query: 2005 RSRSRT-----SPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059
+ S T +PVT S +P S +P S +PLA S +
Sbjct: 2415 STHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSP-----PSEGTTPLASMPVSTTPVV 2469
Query: 2060 RTARGKRSLT---RSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSC 2116
+ G S T S P AS S + P +T + + + ++++ ++
Sbjct: 2470 SSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVAS 2529
Query: 2117 FSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENH 2176
++S TP+D + SS T + +G P + V
Sbjct: 2530 PEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPL----RSMPVSTKP 2585
Query: 2177 AQSRIALALTAISLGTARPPPSM---SAAGLAARMSQVPAPVPLMSLRTAPAANLASRIP 2233
S A L+ + T+ P + S++ A+ + +P P + T+ + L S +P
Sbjct: 2586 LASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTP-SEVSTSLTSILVSTMP 2644
Query: 2234 AASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAP 2293
AS+ A L++ TP D+RT + +SP TA S++ + P + P
Sbjct: 2645 VASSEASTLST--TPV--------DTRTLVTTSTGTSSSPTTAEG-SSMPTSTPGERSTP 2693
Query: 2294 AVNLAGARTPAA---LAALSLT--GSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA-- 2346
N+ + T A + LS T + TP T + SSS T S + P
Sbjct: 2694 LTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPL 2753
Query: 2347 ----TAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLL 2402
+ + +A S + A TS + + ++ + S TS PL
Sbjct: 2754 TSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLT 2813
Query: 2403 DRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCL 2462
+ TP A S++ S S+ + + S P + P+ +A S+ S L
Sbjct: 2814 SMPVNHTPV-ASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTA-SEGSTLL 2871
Query: 2463 IA---QTTPVAGSQS--LSSGAVAT----TTSSAGDHNGMLSVPAPGVPHSDVGEPPAST 2513
+ TTPVA S++ LS+ V T TTS+ G + A G P ST
Sbjct: 2872 TSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSS---PTTAEGT------SMPIST 2922
Query: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
++ + L ++ + + S +S+ S++ + + ++S+ + SS + +EG+S+P+
Sbjct: 2923 PSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPIS-- 2980
Query: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633
TP E R P + + +SS +S+ S + + +S+ ++S+ +S
Sbjct: 2981 ---------TPG------ERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEAS 3025
Query: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
SS +++ + S+PS ++P +P P S +P + S +S
Sbjct: 3026 SSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSS 3085
Query: 2694 SP 2695
SP
Sbjct: 3086 SP 3087
Score = 213 bits (541), Expect = 3e-54
Identities = 562/2639 (21%), Positives = 928/2639 (35%), Gaps = 330/2639 (12%)
Query: 212 SSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTT--PAPKSRRAHRSTSADSA 269
SS S + K TP + + K S + T P + SA ++
Sbjct: 195 SSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQAS 254
Query: 270 SSSDTSRSRSRSAAAKTHTTALAGRSP-------SPASGRRGEGDAPFSEPGTTSTQRPS 322
SS T+ S S +A + + R P S + A + P TST+ S
Sbjct: 255 SSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASS 314
Query: 323 SPETA--TKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQP 380
SP TA T P+S Y + A+ + ST P T
Sbjct: 315 SPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDT-----------ST 363
Query: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
L TT S EP + P+ A T L + S S+P + P ASS +
Sbjct: 364 LVTT--STEPSSLPTTAEAT---------SMLTSTLSEGSTPLTNMPVSTILVASSEAST 412
Query: 441 PKPAPAPG-----SHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRS 495
P + E SSSPT+ + A S TP M S +P + +
Sbjct: 413 TSTIPVDSKTFVTTASEASSSPTTAEDT-SIATSTPSEGSTPLTSMPVSTTPVASSEASN 471
Query: 496 RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSR 555
S TP + S + S P S P + T +
Sbjct: 472 LSTTPVDSKTQVTTSTE----------ASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTM 521
Query: 556 SARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615
+ + S S T + S S TP + PT S TP
Sbjct: 522 PVASSEASTLSTTPVDTSTPVTTSSEASSSSTTP----EGTSIPTSTPSEGSTPLTNMPV 577
Query: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS------ 669
+R + T S S + S S S T A + T + RG +
Sbjct: 578 STRLVVSSEASTTSTTPADSNT-FVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSV 636
Query: 670 RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSE 729
+ A + S TP S + + S S G S + G + +S
Sbjct: 637 STTLVASSEASTLSTTPVD---SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSM 693
Query: 730 RKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC---P 786
N + + + + S+ + S + + + SSP + + + GS+P P
Sbjct: 694 PVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP 753
Query: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846
K+ + + S+ P S + +S SP + + P S+ S + +
Sbjct: 754 VSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPI----STPSEGSPLLT 809
Query: 847 GTPPRQGSITSPQANEQSVTPQRRSC-------FESSPDPELKSRTPSRHSCSGSSPPRV 899
P +TSP+A+ S TP + SSP P + P+ G +P
Sbjct: 810 SIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTS 869
Query: 900 KSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV 959
+ + S S+ +P S SSP+ S TS T +P +++
Sbjct: 870 MPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSM 929
Query: 960 ESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE 1019
P S + T V TP S + SP P G+ +P
Sbjct: 930 PDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGT-TPLTST 988
Query: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS 1079
+LV + S V S+TP L ++ + P TS P S
Sbjct: 989 PVSHTLVANSEASTLSTTPVDSNTP----------LTTSTEASSPPPTAEGTSMPTSTPS 1038
Query: 1080 HSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQ 1139
+P + T+ S+ T + +P+ + S+S G S S +
Sbjct: 1039 EGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTT-YSQASSSSTTADGTSMPTSTYS 1097
Query: 1140 SDSSSYPTVDSNSLL----GQSRLETAESKEKMALPPQEDATASP--------PRQKDKF 1187
S+ +V ++ L S L T + + +A++SP P
Sbjct: 1098 EGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSE 1157
Query: 1188 SPFPVQDRPESSLVF----KDTLRTPPRER------SGAGSSPETKEQNSALPTSSQDEE 1237
P+ P S+ + +TL T P + S SSP + +++PTS+ E
Sbjct: 1158 GTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGE- 1216
Query: 1238 LMEVVEKSEEPAGQILSHL---SSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLE 1294
+S + H SSE +STS ++S V + + + S S + E
Sbjct: 1217 ------RSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPV------TTSAETSSSPTTAE 1264
Query: 1295 AVEVPSMASSWGGPHFS--PEHKELSNSPLRENSFGSPLEFR---------NSGPL---G 1340
+P+ +S G + P L SP +P++ + +S P G
Sbjct: 1265 GTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEG 1324
Query: 1341 TEMNTGFSSEVKEDLNG-------------------PFLNQLETDPSLDMKEQSTRSSGH 1381
T M T SE + L P N S + T S G
Sbjct: 1325 TSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGT 1384
Query: 1382 SSSELSPDA----VEKAGMSSNQSISSPV--LDAVP---RTPSRERSSSASSPEMKDGLP 1432
S +P + +S+ +SS L A P TP + + SSP +G+
Sbjct: 1385 SMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGIS 1444
Query: 1433 ---------RTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIP----RTPSRGRSE 1479
+TP + ++P + T S + +SP + TP+ G S
Sbjct: 1445 IPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI 1504
Query: 1480 CDSSPEPKALPQTPRPRSRSP-SSPELNNKCLTPQ---------RERSGSESSVDQKTVA 1529
S+P + T P S + +S E+N+ TP + S S ++ D ++
Sbjct: 1505 AISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQ 1564
Query: 1530 RTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS---GSSPEVD 1586
+ + S +S + S + + S + DSK + S + GSS +
Sbjct: 1565 TSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTIS 1624
Query: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
+ S SP + S V P A+P A + S + + +P + S S + G
Sbjct: 1625 TPSEGSPLLT----SIPVSTTPVASPEASTLSTTPVDSNSPV---ITSTEVSSSPTPAEG 1677
Query: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTR-KARLSR 1705
S S+ TE P S T R +S T S TP S+P T +AR S
Sbjct: 1678 TSMPTSTYTEGRT--PLTSITVRTTPVASSAISTLSTTPV----DNSTPVTTSTEARSSP 1731
Query: 1706 RSRSASSSPETRSR--TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP 1763
+ +S P + T P S + +E S S S+P T +T
Sbjct: 1732 TTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPT 1791
Query: 1764 SPKPRGLQRSR-SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
+ + + S S T T +S++++ S S V S S
Sbjct: 1792 TAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSS---S 1848
Query: 1823 RSPARQESSRTSSRRRRGRSRTP-PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881
+PA S TS+ + T P S S + ++P T S +P
Sbjct: 1849 PTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSP 1908
Query: 1882 LISRRRSRSRTSPVSRRRSRSRTSV-TRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
+ S ++P R + V T + S + +S + +RTP VT S +P
Sbjct: 1909 TTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTP-VTTYSQASSSP 1967
Query: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
TT + TP + + + P+ S T ++ S T+PV TS
Sbjct: 1968 TTADGTSMPTPAYSEGSTPLTSMPL------STTLVVSSEASTLSTTPVD-------TST 2014
Query: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPR 2060
+ +SP T + +T R TPL S + L + + +
Sbjct: 2015 PATTSTEGSSSPTTAGGTSIQTSTPSERT----TPLAGMPVSTT---LVVSSEGNTLSTT 2067
Query: 2061 TARGKRSLTRSPPAIRRRSASGSSSDRSR-------------SATPPATRNHSGSRTPPV 2107
K +T S A +A GSS S S TP A+ S T PV
Sbjct: 2068 PVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPV 2127
Query: 2108 ALNSSRMSCFSRPSMSPTPLDRC----------RSPGMLEPLGSSRTPMSVLQQAGGSMM 2157
NS ++ + S SP P + R+P P+ ++ S + + +
Sbjct: 2128 DSNSPVITS-TEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPV 2186
Query: 2158 DGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARP---PPSMSAAGLAARMSQVPAP 2214
D TS P ++ A + S GT+ P P S + +S +P
Sbjct: 2187 D-----------TSTPVTNSTE--ARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVV 2233
Query: 2215 VPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPR 2274
S +A + ++ + ++ A + +A +IPT+ L++ TP + ++
Sbjct: 2234 TSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTST-LSEGTTPLTSIPVS----H 2288
Query: 2275 TAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTP-PTAANYPSSSRTPQAP 2333
T VA S V+ T P + T ++ T GT PT+ + ++ + P
Sbjct: 2289 TLVANSEVSTLS----TTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMP 2344
Query: 2334 ASANLVGP--RSAHATAPVNIAGSRTAAALAPASLTSA--RMAPALSGANLTSP--RVPL 2387
S +V S +T P + + T + A +S T+A P + + ++P VP+
Sbjct: 2345 VSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPV 2404
Query: 2388 SAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQA-----PSQSLLPP 2442
S VS S S TP + ++E + SP++ G + PS+ P
Sbjct: 2405 STMPVVSSEAS------THSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 2458
Query: 2443 AQDQPRSPVPSAFSDQ---SRCLIAQTTPVAGSQSLSSGA-----VATTTSSAGDHNGML 2494
A P S P S+ S + +TP+ S SS + S+A + + +L
Sbjct: 2459 AS-MPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLL 2517
Query: 2495 -SVPAPGVPHSDVGEPPASTGAQQP-SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSS 2552
S+P P V P AST + P + + + + E SS++S+ +S +S+ S S+
Sbjct: 2518 TSIPVSTTP---VASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGST 2574
Query: 2553 -------SSSSGSSSSDSEGSSLPVQPEVAL----KRVPSPTPAPKEAVREGRPPEPTPA 2601
S+ +SS S S+ PV + + + SPT A ++ P E + +
Sbjct: 2575 PLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTS 2634
Query: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660
S+ +SS +S+ S++ + + ++S+ +SSS +++ SS + PG ++ P
Sbjct: 2635 LTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTP 2693
Score = 209 bits (532), Expect = 3e-53
Identities = 575/2577 (22%), Positives = 932/2577 (36%), Gaps = 292/2577 (11%)
Query: 231 SPTPKSKRKSKDKKRKRSRST--TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288
SP P ++ S RST T P S+ A + S+S S + +A+T +
Sbjct: 1199 SPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSS 1258
Query: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348
+ S + EG + ST +SPE +T ++P + K +
Sbjct: 1259 SPTTAEGTSLPTSTTSEGSTLLTSI-PVSTTLVTSPEASTLL-TTPVDTKGPVVTSNEVS 1316
Query: 349 RPSPSPERSSTGPEP------------PAPTPLLAERHGGSPQPLATTPLSQE-PVNPPS 395
SP+P ++ P P T L+A + L+TTP+ PV +
Sbjct: 1317 S-SPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVAS---SAISILSTTPVDNSTPVTTST 1372
Query: 396 EASPTRDRSPPKSPEKLPQSSSSESSPP------SPQPTKVSRHASSSPESPKPAPAPGS 449
EA + S S +P S+ SE + P S P VS AS+ +P PG+
Sbjct: 1373 EACSSPTTSEGTS---MPNSNPSEGTTPLTSIPVSTTPV-VSSEASTLSATPVDTSTPGT 1428
Query: 450 -HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRS 508
E +SSPT+ S TP + + S +P + S TP
Sbjct: 1429 TSAEATSSPTTAE-GISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVV 1487
Query: 509 RSPQWRRSRS-AQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSP 567
S S + A+ + S G + P S T S + + +P
Sbjct: 1488 TSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPV---STTTVASSEINSLSTTPAVTSTP 1544
Query: 568 ATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRT 627
T S +P + +T + + S + + S TP S+T
Sbjct: 1545 VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPID--SKT 1602
Query: 628 RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTP-ARRSGRSRSRTP 686
+ + S + A S + S TP+ + P S TP A + S TP
Sbjct: 1603 QVTASTEASSSTTAEGSSMTIS-TPSEGSPLLTSIPV------STTPVASPEASTLSTTP 1655
Query: 687 ARRGR--------SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ 738
S S TP G S S GR+ + R +SS S T
Sbjct: 1656 VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPV 1715
Query: 739 RRSRSNSSP--EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR 796
NS+P ++R S S S P S G++P T P
Sbjct: 1716 ----DNSTPVTTSTEARSSPTTSEGTSMPNSTPSE---------GTTPLTSIPVSTTPVL 1762
Query: 797 SRSGS--SQPKAKSRTPPRRS-RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG 853
S S S + TP S ++SSP + + P+ +P + TP
Sbjct: 1763 SSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTP----LTSTPVSHT 1818
Query: 854 SITSPQANEQSVTPQ-------RRSCFESSPDP----ELKSRTPSRHSCSGSSPPRVKSS 902
+ + +A+ S TP + SSP P + + TPS S + +S P ++
Sbjct: 1819 LVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTT 1878
Query: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962
++ + S++P + + Q S S +++ S TS TPR R P +++
Sbjct: 1879 VASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTS--TPREGRP--PLTSIPVS 1934
Query: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK 1022
S ++ T TP S SP + P P+ S +P
Sbjct: 1935 TTTVASSEINTLSTTLADTRTPVTTYSQASSSP-TTADGTSMPTPAYSEGSTPLTSMPLS 1993
Query: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSE 1082
+LV S S V +STP S G SS G + S+ ++P S
Sbjct: 1994 TTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVST 2053
Query: 1083 SPSLQSKSQT---SPKGGRSRSSSPVTELASRSPIRQDRGEFSA----SPMLKS---GMS 1132
+ + S+ T +P +++ ++ TE +S + SA SP+L S +
Sbjct: 2054 TLVVSSEGNTLSTTPVDSKTQVTNS-TEASSSATAEGSSMTISAPSEGSPLLTSIPLSTT 2112
Query: 1133 PEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALP-PQEDATASPPRQKDKFSPF- 1190
P S S S+ P VDSNS S E + P P E + D+ +P
Sbjct: 2113 PVASPEASTLSTTP-VDSNS-------PVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLT 2164
Query: 1191 --PVQDRPESSLVFKDTLRTPPRERSG-------AGSSPETKEQNSALPTSSQDEELMEV 1241
PV +S TL T P + S A SSP T E S +PTS+ E
Sbjct: 2165 SMPVSTTVVASSAIS-TLSTTPVDTSTPVTNSTEARSSPTTSEGTS-MPTSTPSEG---- 2218
Query: 1242 VEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSM 1301
S +S + E ST S+ V+ V+ + + + S + E +P+
Sbjct: 2219 ---STPFTSMPVSTMPVVTSEASTL---SATPVDTSTPVTTSTEATSSPTTAEGTSIPTS 2272
Query: 1302 ASSWGGPHFSP-----------EHKELSNSPLRENS-FGSPLEFRNSGPL--GTEMNTGF 1347
S G + E LS +P+ N+ F + E + P GT M T
Sbjct: 2273 TLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTST 2332
Query: 1348 SSE-----VKEDLNGPFLNQLETDP-SLDMKEQSTRSSGHSSSELSPDAVEKAGM-SSNQ 1400
SSE + ++ + ET S + ST + +S + SP + M +S
Sbjct: 2333 SSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTY 2392
Query: 1401 SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRS-RSGSSPGLRDGSGTPSRHSL 1459
S S L +VP + SS AS+ TP S + SSP +G+ P+
Sbjct: 2393 SEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPS 2452
Query: 1460 SGSSP-GMKDIPRTP--SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRER 1516
G++P + TP S ++P + P T + + SSP + P
Sbjct: 2453 EGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTS--TEASSSPTTAEDIVVPISTA 2510
Query: 1517 SGSESSVDQKTVARTPLGQRSRSG-SSQELDVK-PSASPQERSESDSSPDSKAKTRTPLR 1574
S + + V+ TP+ S S+ +D P + E S S +S + + +
Sbjct: 2511 SEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYS 2570
Query: 1575 QRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPR 1634
+ S S V +K S S ++P P S S ++ + + P + P
Sbjct: 2571 EGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTS-MPISTPS 2629
Query: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT---ARRGSRSSPEPKTKSRTPPRRRSS 1691
+ +S P SS + P +RT G+ SSP S P
Sbjct: 2630 EVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGE 2689
Query: 1692 RSSPELTRKARLSRRSRSASSSPETRSRTP-----PRHRRSPSVSSPEPAEKSRSSRRRR 1746
RS+P LT L + A+S T S TP P + + SSP AE + S R
Sbjct: 2690 RSTP-LTNI--LVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGT--SMRIS 2744
Query: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
+ S T TS S P + S + + + + SS +T+ S
Sbjct: 2745 TPSDGSTPLTSILV-STLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTS 2803
Query: 1807 RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRS 1866
T + +P + T S S TS K S S T+ S
Sbjct: 2804 TPSETSTPLTSMPVN-HTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIS 2862
Query: 1867 RASPATHRRSR---SRTPLISRRRSRSRTSPVSRR---RSRSRTSVTRRRSRSRASPVSR 1920
AS + + S TP+ S S T+PV + + S + + + P+S
Sbjct: 2863 TASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIST 2922
Query: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTP-----PVTRRRSRSRTPPVTRRRSRSRTS 1975
S TP + S + + S TP PVT S +P S ++
Sbjct: 2923 P-SEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPIST 2981
Query: 1976 PITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPA-------IRR 2028
P RR + S T + S S ++R + + T PVT S +P I
Sbjct: 2982 PGERRTPLTSMSVSTMPVASSEASTLSRTPADTST-PVTTSTEASSSPTTAEGTGIPIST 3040
Query: 2029 RSRSRTPLLPRKRSRSRSPLAIRRRSR-SRTPRTARGKRSLTRSPPAIRRRSASGSSSDR 2087
S TPL S +P+AI S S TP + + P + S S +
Sbjct: 3041 PSEGSTPLT--SIPVSTTPVAIPEASTLSTTP--------VDSNSPVVTSTEVSSSPTPA 3090
Query: 2088 SRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMS 2147
++ P +T + + V ++++ ++ + ++S TP+D SS T
Sbjct: 3091 EGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSE 3150
Query: 2148 VLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR 2207
+ +G P T + + S L+ T + T + + + A
Sbjct: 3151 GTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDS--TLSATPVDTSTPVTTSTEATSSTTAE 3208
Query: 2208 MSQVPAPVP---LMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAA 2264
+ +P P + L + P +N P AS+ A L++ TP DS TP
Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPVSNT----PVASSEASILST--TPV--------DSNTPLT 3254
Query: 2265 AAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYP 2324
+ +SP TA S + + P + P ++ + T A + S T + P
Sbjct: 3255 TSTEASSSPPTAEGTS-MPTSTPSEGSTPLTSMPVSTTTVASSETS--------TLSTTP 3305
Query: 2325 SSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPR 2384
+ + TP S P A T+ P S S P N++
Sbjct: 3306 ADTSTPVTTYSQASSSPPIADGTS-------------MPTSTYSEGSTPL---TNMSFST 3349
Query: 2385 VPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQ 2444
P+ + E + T+P +D + T + S S T+E P+S +PS+ P A
Sbjct: 3350 TPVVSSEASTLSTTP--VDTSTPVTTSTEASLSPTTAEGTSIPTS----SPSEGTTPLAS 3403
Query: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
P S P S+ + TTPV + +++ A+++ + + +
Sbjct: 3404 -MPVSTTPVVSSEVNTL---STTPVDSNTLVTTSTEASSSPTIAEGTSL----------- 3448
Query: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
P ST ++ + L+ + + +SS +S+ S++ +S+ ++SS + SS + +E
Sbjct: 3449 -----PTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAE 3503
Query: 2565 GSSLPV----QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS--- 2617
+S+P + L +P T + P + SSS +SSS ++
Sbjct: 3504 VTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQV 3563
Query: 2618 ----SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
S+ S SSS ++ SS+ +SS +S+ S+PS + P ++ PP
Sbjct: 3564 TTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPP 3620
Score = 207 bits (528), Expect = 9e-53
Identities = 549/2572 (21%), Positives = 921/2572 (35%), Gaps = 302/2572 (11%)
Query: 250 STTPAPKSRRAHRSTSADSASS--SDTSRSRSRSAAAKTHTTALAGRS-PSPASGRRGEG 306
STTP + ST S+ + TS S +T T++ R+ P +S
Sbjct: 1652 STTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLS 1711
Query: 307 DAPF--SEPGTTSTQRPSSPETA--TKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE 362
P S P TTST+ SSP T+ T P+S +PS +
Sbjct: 1712 TTPVDNSTPVTTSTEARSSPTTSEGTSMPNS-----------------TPSEGTTPLTSI 1754
Query: 363 PPAPTPLLAERHGGSPQPLATTPL-SQEPVNPPSEA--SPTRDRSPPKSPEKLPQSSSSE 419
P + TP+L+ L+ TP+ + PV +EA SPT L + +
Sbjct: 1755 PVSTTPVLSSE----ASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPL 1810
Query: 420 SSPPSPQPTKVSRHASSSPESPKPAPAPG-SHREISSSPTSKNRSHGRAKRDKSHSHTPS 478
+S P + AS+ +P + +P + +SSSPT + A S T
Sbjct: 1811 TSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT-SIATSTPSEGSTAL 1869
Query: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
+ S + + + S TP + Q S S S P R P
Sbjct: 1870 TSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQV--SSSPTTADGSSMPTSTPREGRPP 1927
Query: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
S T + + +R+P T S +P + TPA +
Sbjct: 1928 LTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPL 1987
Query: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSR-SRSPARRSGRS-RSRTPARRG 656
+ S + + + S TP T +P + S SP G S ++ TP+ R
Sbjct: 1988 TSMPLSTTLVVSSEASTLSTTPVD----TSTPATTSTEGSSSPTTAGGTSIQTSTPSERT 2043
Query: 657 RSRSRTP-------ARRGRSRSRTPARRSGRSRSRTPAR-----RGRSRSRTPRRGRSRS 704
+ P + G + S TP + + T A G S + + S
Sbjct: 2044 TPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPL 2103
Query: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE---MKKSRISSRRSRS 761
+ + + +P+ S + + + TS S S E M+ S S RR+
Sbjct: 2104 LTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPL 2163
Query: 762 LSSPRSKAKSRLSLRRSLSG-----SSPCPKQKSQTPPRRSRSGSSQPKA---KSRTP-- 811
S P S S +LS S+P + G+S P + + TP
Sbjct: 2164 TSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFT 2223
Query: 812 -----------PRRSRSSSSPPPKQKSKTPSRQSHSS-------SSPHPKVKSGTPPRQG 853
S S++P T S ++ SS S P + GT P
Sbjct: 2224 SMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTP--- 2280
Query: 854 SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP-PRQSPSRS 912
+TS + V S ++P + S TP S SSPP T P + S
Sbjct: 2281 -LTSIPVSHTLVANSEVSTLSTTP---VDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEG 2336
Query: 913 SSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGS 972
++P ++ + + + S +P+ ++ T SP + + +P ++S
Sbjct: 2337 NTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSP-TTADDTSMPTSTYSEG 2395
Query: 973 SSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGS 1032
S+P T V T P S S V TP S S SP E + G+
Sbjct: 2396 STPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGT 2455
Query: 1033 LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQT 1092
L + S+TP S G S T+P DTS+P + + S ++
Sbjct: 2456 TPLASMPVSTTPVVSSEAGTLS--------TTP---VDTSTPMTTSTEASSSPTTAEDIV 2504
Query: 1093 SPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNS 1152
P S S+ +T + P+ S +P+ SPE S S VDSNS
Sbjct: 2505 VPISTASEGSTLLTSI----PV-------STTPVA----SPEASTL-----STTPVDSNS 2544
Query: 1153 LLGQSR--LETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPP 1210
+ S +A S E ++P + S P + PV +P +S TL T P
Sbjct: 2545 PVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRS-----MPVSTKPLASSE-ASTLSTTP 2598
Query: 1211 RERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMST--SNF 1268
+ S T + S+ PT+++D + + E + + S L S + S+ S
Sbjct: 2599 VDTS---IPVTTSTETSSSPTTAKDTSMP--ISTPSEVSTSLTSILVSTMPVASSEASTL 2653
Query: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG 1328
++P V+ R V+ + S S + E SM +S G +P L ++ L NS
Sbjct: 2654 STTP-VDTRTLVTTSTGTSSSPTTAEG---SSMPTSTPGERSTPLTNILVSTTLLANSEA 2709
Query: 1329 SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSP 1388
S L ++ P+ T S+E T ST S G S+ L+
Sbjct: 2710 STL---STTPVDTSTPVTTSAEASSS---------PTTAEGTSMRISTPSDG--STPLTS 2755
Query: 1389 DAVEKAGMSSNQS--ISSPVLD-AVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSP 1445
V ++S+++ +S+ +D ++P T S E SSS ++ E+ TPS S +S
Sbjct: 2756 ILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSM 2815
Query: 1446 GLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP----------QTPRP 1495
+ S ++P P T S S ++ E +P T P
Sbjct: 2816 PVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIP 2875
Query: 1496 RSRSP-SSPELNNKCLTPQRER----SGSESSVDQKTVARTPLGQRSRSGSSQEL-DVKP 1549
S +P +S E + TP + +E S T T + + S S L +
Sbjct: 2876 VSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILV 2935
Query: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609
S P SE+ + + TRTP+ + + SSP + + +P
Sbjct: 2936 STVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVS 2995
Query: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS-STESSPEHPPKSRTA 1668
P A S ++S + PA + P + + +SS G ST S P S
Sbjct: 2996 TMPVASS--EASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPV 3053
Query: 1669 RRGSRSSPEPKTKSRTPPRRRSS-------RSSPELTRKARLSRRSRSASSSPETRSRTP 1721
+ PE T S TP S SSP + + S S+P T
Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113
Query: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781
S ++S+ S+ S + + TTS P+ P +
Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVST 3173
Query: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841
D + S+ + S + G+ + +P+ + TS
Sbjct: 3174 MLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPV---- 3229
Query: 1842 SRTPPTSRKRSRSRTSPAPWKR-----SRSRASPATHRRSRSRTPLISRRRSRSRTSPVS 1896
S TP S + S T+P + + +SP T + T S + + PVS
Sbjct: 3230 SNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVS 3289
Query: 1897 RRR-SRSRTSVTRRRSRSRASPVSRRRSRSRTPPV-------TRRRSRSRTPTTRRRSRS 1948
+ S TS ++PV+ S +PP+ T S TP T S S
Sbjct: 3290 TTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNM-SFS 3348
Query: 1949 RTPPVTRRRSRSRTPPV-----TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTR 2003
TP V+ S T PV + + SP T + TS + + + PV+
Sbjct: 3349 TTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVST 3408
Query: 2004 RRSRSR------TSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKR-SRSRSPLAIRRRSRS 2056
S T+PV + + A + + LP S +PL+I S
Sbjct: 3409 TPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIM--PLS 3466
Query: 2057 RTPRTARGKRSLTRSP-----PAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNS 2111
TP + +L+ +P P + S + ++ P +T + + +++
Sbjct: 3467 TTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVST 3526
Query: 2112 SRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP------ 2165
+ ++ ++S TP+D SS + V + +G
Sbjct: 3527 TPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSST 3586
Query: 2166 --DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTA 2223
S P + R T+ + PP + ++ S+V P+ +M + T
Sbjct: 3587 YVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTP-SEVSTPLTIMPVSTT 3645
Query: 2224 PA----ANLASRIPAASAAAMNLAS--ARTPAIPTAVNL-----ADSRTPAAAAAMNL-- 2270
A AS +P ++ + ++ + +P P + ++ TP ++
Sbjct: 3646 SVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTR 3705
Query: 2271 --ASPRTAVAPSAVNLADPRTPTAPAVNLAGA--------RTPAALAALSLTGSGTPPTA 2320
+S + ++ +V + P T + A++ + P ++ L T +
Sbjct: 3706 VTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPV 3765
Query: 2321 ANYPSSSRTPQAPASANLVGPRSAH--ATAPVNIAGSRTAAALAPASLTSARMAPALSGA 2378
+P SS TP P+ + +A +++P + G+ T + ++ +S
Sbjct: 3766 TRFPESS-TPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPI 3824
Query: 2379 NLTSPRVPLSAYERVSGRTSPPLLD--RARSRTPPSAPSQSRM--TSERAPSPSSRMGQA 2434
++ SP S G TS PLL +A S + P+ + R+ TSER+ ++ +
Sbjct: 3825 SVMSPS-EASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVST 3883
Query: 2435 PSQSLLPPAQDQPRSPVPSA--FSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNG 2492
+ P A P+ ++ F+ + T PVA + S+S V T S+ G
Sbjct: 3884 TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVS---VITEGSTPGT--- 3937
Query: 2493 MLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSS 2552
+ +P+ V S PA+TGA + +S+ ++ S+S
Sbjct: 3938 TIFIPSTPVTSSTADVFPATTGAVSTPVI--------------------TSTELNTPSTS 3977
Query: 2553 SSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612
SSS+ +S S ++ + P T AP V P TP R ++S+S
Sbjct: 3978 SSSTTTSFSTTKEFTTPAM----------TTAAPLTYVTMSTAPS-TPRTTSRGCTTSAS 4026
Query: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664
+ S++S+ +S+S ++ + SS SS S+ +S + P P + P S
Sbjct: 4027 TLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTS 4078
Score = 200 bits (508), Expect = 2e-50
Identities = 455/2139 (21%), Positives = 758/2139 (35%), Gaps = 236/2139 (11%)
Query: 732 NKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQ 791
N TS S ++ +P + +R++ SR+ S S + + + S P+
Sbjct: 88 NPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDV 147
Query: 792 TPPRRSRSGSSQPKAKSRTPPRRS-RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP 850
S S A T P S + +S K TP S +SS +S T P
Sbjct: 148 PMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIP 207
Query: 851 R----QGS--ITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSC-SGSSPPRVKSST 903
+ +GS +TS A+ V ++P ++ TP S + SSP + +
Sbjct: 208 KSTNSEGSTPLTSMPASTMKVASSEAITLLTTP---VEISTPVTISAQASSSPTTAEGPS 264
Query: 904 PPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRL 963
+PS S+P ++ + S + + S +P+ S SP + E
Sbjct: 265 LSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSP-TTAEGTS 323
Query: 964 LPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK- 1022
+P +++ S+P T T P + S V T S S P E +
Sbjct: 324 IPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSM 383
Query: 1023 --------DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSP 1074
+ + + P S L A ++ST + + ++ +SP DTS
Sbjct: 384 LTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIA 443
Query: 1075 EVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPE 1134
S +P T+P S+ T + S++ + S+ P + P
Sbjct: 444 TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPT 503
Query: 1135 QSRFQSD--------------SSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA--TA 1178
+ + SS T+ + + + + T+ + P+ + T+
Sbjct: 504 STPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTS 563
Query: 1179 SPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER-----SGAGSSPETKEQNSALPTSS 1233
+P + PV R S T TP S SS T + +++PTS+
Sbjct: 564 TPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTST 623
Query: 1234 QDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASL 1293
E + S +S+ L S ++ S+ V+ V+ + + + S +
Sbjct: 624 YSERGTTITSMS----------VSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTA 673
Query: 1294 EAVEVPSMASSWGGPHF-----------SPEHKELSNSPLRENSFGSPLEFRNSGPL--- 1339
E +P+ + G S E LS +P+ ++ + +S P
Sbjct: 674 EGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTAD 733
Query: 1340 GTEMNTGFSSEVKEDLNG-PFLNQLETDP-----SLDMKEQSTRSSGHSSSELSPDAVEK 1393
G M T SE L P L T S + ST + + + SP E
Sbjct: 734 GASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEG 793
Query: 1394 AGMS-SNQSISSPVLDAVPR--TP-SRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
M S S SP+L ++P TP + +S+ S+ + P T S + SSP +
Sbjct: 794 TSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTS--TEVSSSPTPAE 851
Query: 1450 GSGTPSRHSLSGSSP--------------GMKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495
G+ P+ G +P + + TP + +S E ++ P T
Sbjct: 852 GTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEG 911
Query: 1496 RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPS-ASPQ 1554
S S+P + LT + + S + +T++ TP+ + +S E P+ A
Sbjct: 912 TSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGT 971
Query: 1555 ERSESDSSPDSKAKTRTPL------RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
S S + T TP+ + + S+ VDS + L+ S SSP +
Sbjct: 972 SIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTT--STEASSPPPTAEG 1029
Query: 1609 RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGP--------SPEGSSSTESSPE 1660
+ P + S+P + P + S + + S S SSST +
Sbjct: 1030 TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGT 1089
Query: 1661 HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRT 1720
P S T GS +R +S S + S ASSSP T T
Sbjct: 1090 SMPTS-TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT 1148
Query: 1721 -----PPRHRRSPSVSSPEPAEKSRSSRRRRSASSP-RTKT---TSRRGRSPSPKPRGLQ 1771
PP +P S P SS +++P +KT TS SP P
Sbjct: 1149 SIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTS 1208
Query: 1772 RSRSRSRREKTRTTR---RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ 1828
S T T R SS++++ + + VT S S SP
Sbjct: 1209 MPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTT-----SAETSSSPTTA 1263
Query: 1829 E-SSRTSSRRRRGR--------SRTPPTSRKRSRSRTSPAPWK-----RSRSRASPATHR 1874
E +S +S G S T TS + S T+P K + +SP
Sbjct: 1264 EGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAE 1323
Query: 1875 RSRSRTPLISRRRSRSRTSPVSRRR-SRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933
+ T S R+ + PV+ + S S+ ++PV+ +P +
Sbjct: 1324 GTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEG 1383
Query: 1934 RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRR-----SRSRTSP 1988
S + + + + PV S TP V+ S +P+ + + +SP
Sbjct: 1384 TSMPNSNPSEGTTPLTSIPV------STTPVVSSEASTLSATPVDTSTPGTTSAEATSSP 1437
Query: 1989 VTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSR-SRTPL-----LPRKRS 2042
T TS + ++ ++ PV S TP A S S TP+ + +
Sbjct: 1438 TTAEGISIPTSTPSEGKTPLKSIPV------SNTPVANSEASTLSTTPVDSNSPVVTSTA 1491
Query: 2043 RSRSP-------LAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS-------------G 2082
S SP +AI S T T+ + T + I S +
Sbjct: 1492 VSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQA 1551
Query: 2083 SSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPS--MSPTPLDRCRSPGMLEPLG 2140
SSS + T T +S TP +L S M S + +S TP+D
Sbjct: 1552 SSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEAS 1611
Query: 2141 SSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMS 2200
SS T A GS M P TS+P S +A S + P S S
Sbjct: 1612 SSTT-------AEGSSMTISTPSEGSPLLTSIPV----STTPVASPEASTLSTTPVDSNS 1660
Query: 2201 AAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSR 2260
+ +S P P S+ T+ R P S A + + D+
Sbjct: 1661 PVITSTEVSSSPTPAEGTSMPTSTYTE--GRTPLTSITVRTTPVASSAISTLSTTPVDNS 1718
Query: 2261 TPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTP--- 2317
TP + +SP T+ S N + P T P ++ + TP L++ + T S TP
Sbjct: 1719 TPVTTSTEARSSPTTSEGTSMPN-STPSEGTTPLTSIPVSTTPV-LSSEASTLSATPIDT 1776
Query: 2318 --PTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM---- 2371
P + ++S A ++ S T + S T A + AS S
Sbjct: 1777 STPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSN 1836
Query: 2372 APALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRM 2431
+P ++ ++S P E S TS P S + S T+ A S ++ +
Sbjct: 1837 SPVVTSTAVSSSPTPA---EGTSIATSTP------SEGSTALTSIPVSTTTVASSETNTL 1887
Query: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHN 2491
P+ + P S P+ S + +TP G L+S V+TTT ++ + N
Sbjct: 1888 STTPAVTSTPVTTYAQVSSSPTTADGSS---MPTSTPREGRPPLTSIPVSTTTVASSEIN 1944
Query: 2492 GMLSVPA----PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSS 2547
+ + A P +S P + A + + S S++ SS +S+
Sbjct: 1945 TLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAST 2004
Query: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRS 2607
S++ +S +++ +EGSS P + + TP+ + G P T
Sbjct: 2005 LSTTPVDTSTPATTSTEGSSSPTT--AGGTSIQTSTPSERTTPLAGMPVSTTLVV----- 2057
Query: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK 2667
SS ++ S++ S + ++S+ +SSS+++ SS + S+PS P ++P +P
Sbjct: 2058 --SSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVA 2115
Query: 2668 PPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS 2706
P S +P + S +S SP+ S Q S
Sbjct: 2116 SPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTS 2154
Score = 194 bits (493), Expect = 1e-48
Identities = 560/2668 (20%), Positives = 922/2668 (34%), Gaps = 342/2668 (12%)
Query: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTS-TQRPS 322
TS +S+ +SDT + T T R+ S ++ D+ P +T T P+
Sbjct: 92 TSIESSVTSDTP------GVSSTRMTPTESRTTSESTS-----DSTTLFPSSTEDTSSPT 140
Query: 323 SPETATKQPSSPYEDKDKDKKEKSATRPSPSPE-------------------RSSTGPEP 363
+PE S+P E+ +T P PS E ++S+ P
Sbjct: 141 TPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTT 200
Query: 364 PAPTPLLAERHGGSPQPLATTPLSQEPV---------------NPPSEASPTRDRSP--P 406
P T + + PL + P S V + P S SP
Sbjct: 201 PESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTA 260
Query: 407 KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPG-----SHREISSSPTSKN 461
+ P + S S+P + P V SS + PA + E SSSPT+
Sbjct: 261 EGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTT-- 318
Query: 462 RSHGRAKRDKSHSH--TPSRRMGRSRSPATAKRGRSRSRTP--TKRGHSRSRSPQWRRSR 517
+ G + +++ TP S P + S TP T + S P
Sbjct: 319 -AEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPS-SLPT 376
Query: 518 SAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRT 577
+A+ S G + P S + S S + S S T
Sbjct: 377 TAEATSMLTSTLSEGSTPLTNMP-VSTILVASSEASTTSTIPVDSKTFVTTASEASSSPT 435
Query: 578 PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS 637
A + TP S TP S TP + + + S+T+ + S
Sbjct: 436 TAEDTSIATSTP----SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASS 491
Query: 638 RSPARRSGRSRSRTPAR-----RGRSRSRTPARRGRSR--------SRTPARRSGRSRSR 684
P + TP+ S S P + + TP S + S
Sbjct: 492 SPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSS 551
Query: 685 TPARRGRS-RSRTPRRGRS-------RSRSLVRRGRSHSRTPQRRGRS--GSSSERKNKS 734
+ G S + TP G + +R +V S + T + +SSE + S
Sbjct: 552 STTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSS 611
Query: 735 RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP 794
T++ S S+ + + I+S S S + S S LS + ++P T
Sbjct: 612 TTAEGTSMPTSTYSERGTTITS-MSVSTTLVASSEASTLS-TTPVDSNTPVTTSTEATSS 669
Query: 795 RRSRSGSSQPKA---KSRTP-----------PRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
+ G+S P + + TP S+ S P S + + +SSSP
Sbjct: 670 STTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSP 729
Query: 841 HPKVKSGTP---PRQGS--ITSPQANEQSVTPQRRSCFESSP-DPELKSRTPSRHSCS-- 892
+ P P +GS +TS ++ +T S ++P D T + SCS
Sbjct: 730 TTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPT 789
Query: 893 ---GSSPPRVKSSTPPRQSPSRSSSP-------QPKVKAII-------SPRQRSHSGSSS 935
G+S P STP SP +S P P+ + SP S SSS
Sbjct: 790 TTEGTSMP---ISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSS 846
Query: 936 PSPSRVTSRTTPRRSRSVSPCSNV------------------------------ESRLLP 965
P+P+ TS T S +P +++ E+R P
Sbjct: 847 PTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSP 906
Query: 966 RYSHSGS---------SSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPC 1016
S S S+P T + T P S V TP S + SP
Sbjct: 907 TTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPT 966
Query: 1017 PQEKSK---------DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH 1067
E + + + S P S +L A ++ST + L ++ + P
Sbjct: 967 TAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPT 1026
Query: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML 1127
TS P S +P + T+ S+ T + +P+ + S+S
Sbjct: 1027 AEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPV-TTYSQASSSSTT 1085
Query: 1128 KSGMSPEQSRFQSDSSSYPTVDSNSLL----GQSRLETAESKEKMALPPQEDATASP--- 1180
G S S + S+ +V ++ L S L T + + +A++SP
Sbjct: 1086 ADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTA 1145
Query: 1181 -----PRQKDKFSPFPVQDRPESSLVF----KDTLRTPPRE------RSGAGSSPETKEQ 1225
P P+ P S+ + +TL T P + S SSP +
Sbjct: 1146 EGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAE 1205
Query: 1226 NSALPTSSQDEELMEVVEKSEEPAGQILSH---LSSELKEMSTSNFESSPEVEERPAVSL 1282
+++PTS+ E+S + H SSE +STS ++S V+
Sbjct: 1206 VTSMPTSTPG-------ERSTPLTSMPVRHTPVASSEASTLSTSPVDTS------TPVTT 1252
Query: 1283 TLDQSQSQASLEAVEVPSMASSWGGPHFS--PEHKELSNSPLRENSFGSPLEFRNSGPLG 1340
+ + S S + E +P+ +S G + P L SP +P++ GP+
Sbjct: 1253 SAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVD--TKGPVV 1310
Query: 1341 TEMNTGFSSEVKEDLNGPFLNQLE-TDPSLDMKEQSTRSSGHSSSELSPDAVEKAG--MS 1397
T S E + P E P + +T + + S LS V+ + +
Sbjct: 1311 TSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTT 1370
Query: 1398 SNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP---SRRSRSGSSPGLRDGSGTP 1454
S ++ SSP P+ S ++P + TP S S ++P GT
Sbjct: 1371 STEACSSPTTSEGTSMPN-SNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTT 1429
Query: 1455 SRHSLSG--SSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTP 1512
S + S ++ G+ TPS G++ S P + S + + N+ +T
Sbjct: 1430 SAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTS 1489
Query: 1513 QRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP 1572
S + TP GS+ + S + SE +S + A T TP
Sbjct: 1490 TAVSSSPTPAEGTSIAISTP-----SEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTP 1544
Query: 1573 LRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL 1632
+ S++ SSP + + GS+P S +++ + +
Sbjct: 1545 VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQV 1604
Query: 1633 PRRSRSGSSSKGRGPSPEGSSSTESSP--EHPPKSRTARRGSRSSPEPKTKSRTPPRRRS 1690
+ + SS+ G S S+ +E SP P S T +SPE T S TP S
Sbjct: 1605 TASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTT----PVASPEASTLSTTPVDSNS 1660
Query: 1691 SRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS 1750
+ + S +S T RTP S +V + A + S+ +
Sbjct: 1661 PVITSTEVSSSPTPAEGTSMPTSTYTEGRTP---LTSITVRTTPVASSAISTLSTTPVDN 1717
Query: 1751 PRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRV 1810
TTS RS G S T T S S S S +
Sbjct: 1718 STPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLT--------SIPVSTTPVLSSEASTL 1769
Query: 1811 TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKR---SRSR 1867
+ + + +P + TSS + P ++ + + P + S
Sbjct: 1770 S-----ATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSE 1824
Query: 1868 ASPATHRRSRSRTPLISRRRSRSRTSP------VSRRRSRSRTSVTRRRSRSRASPVSRR 1921
AS + S +P+++ S +P + S T++T + S
Sbjct: 1825 ASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSET 1884
Query: 1922 RSRSRTP-----PVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP 1976
+ S TP PVT S +PTT S P T R R PP+T + T
Sbjct: 1885 NTLSTTPAVTSTPVTTYAQVSSSPTT--ADGSSMPTSTPREGR---PPLTSIPVSTTTVA 1939
Query: 1977 ITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPL 2036
+ + S T TR +PVT S++ +SP T + TP S TPL
Sbjct: 1940 SSEINTLSTTLADTR-------TPVT-TYSQASSSPTTADGTSMPTP----AYSEGSTPL 1987
Query: 2037 LPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPAT 2096
S + ++ + S TP + S PA S GSSS + T T
Sbjct: 1988 TSMPLS-TTLVVSSEASTLSTTP--------VDTSTPA--TTSTEGSSSPTTAGGTSIQT 2036
Query: 2097 RNHSGSRTPPVALNSSRMSCFSRP--SMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGG 2154
S TP + S S ++S TP+D + ++ T S A G
Sbjct: 2037 STPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDS-------KTQVTNSTEASSSATAEG 2089
Query: 2155 SMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAP 2214
S M P TS+P S +A S + P S S + +S P P
Sbjct: 2090 SSMTISAPSEGSPLLTSIP----LSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIP 2145
Query: 2215 VPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPR 2274
S++T+ ++ + + + + +AS+ + T D+ TP + +SP
Sbjct: 2146 TEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTP--VDTSTPVTNSTEARSSPT 2203
Query: 2275 TAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPA 2334
T+ S + + P + P ++ + P + S + T+ +S+ +P
Sbjct: 2204 TSEGTS-MPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPT 2262
Query: 2335 SA---NLVGPRSAHATAPV-NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAY 2390
+A ++ + T P+ +I S T A + S S P S T+ S
Sbjct: 2263 TAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLST--TPVDSNTPFTTSTEASSPP 2320
Query: 2391 ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP 2450
G TS P + TP + S T+ A +S + P+ + P
Sbjct: 2321 PTAEG-TSMPTSTSSEGNTPLTRMPVS--TTMVASFETSTLSTTPADTSTPVTTYSQAGS 2377
Query: 2451 VPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA-PGVPHSDVGEP 2509
P+ D S + +T GS L+S V+T + + + + P P + E
Sbjct: 2378 SPTTADDTS---MPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEA 2434
Query: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSS---SSSSSSSSSSSSSSSGSSSSDSEGS 2566
+S + +++ P++ +S S++ SS + + S++ +S ++ +E S
Sbjct: 2435 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEAS 2494
Query: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
S P E + VP T + + P TP S+ S++ S+S +S+
Sbjct: 2495 SSPTTAEDIV--VPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEI 2552
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLR 2686
SSS++S+ +S +S+ S S+P +++P P S +P +
Sbjct: 2553 SSSATSAEGTSMPTSTYSEGSTPL------RSMPVSTKPLASSEASTLSTTPVDTSIPVT 2606
Query: 2687 DSRSLSYSPVERRRPSPQPSPRDQQSSS 2714
S S SP + S S + S+S
Sbjct: 2607 TSTETSSSPTTAKDTSMPISTPSEVSTS 2634
Score = 179 bits (453), Expect = 4e-44
Identities = 518/2316 (22%), Positives = 792/2316 (34%), Gaps = 343/2316 (14%)
Query: 250 STTPAPKSRRAHRSTSADSASSSDTSRSRS-RSAAAKTHTTALAGRSPSPASGRRGEGDA 308
STTP S A +TS + +SS T+ S +++ TT LAG S EG+
Sbjct: 2006 STTPVDTSTPA--TTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNT 2063
Query: 309 PFSEPGTTSTQRPSSPE---TATKQPSS-----PYEDKDKDKKEKSATRPSPSPERS--- 357
+ P + TQ +S E +AT + SS P E +T P SPE S
Sbjct: 2064 LSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLS 2123
Query: 358 ----------------STGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTR 401
S+ P P T + + PL + P+S V S A T
Sbjct: 2124 TTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVV--ASSAISTL 2181
Query: 402 DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSP--TS 459
+P + + S+ + SSP + + T S +P P + +S+ P TS
Sbjct: 2182 STTPVDTSTPVTNSTEARSSPTTSEGT------SMPTSTPSEGSTPFTSMPVSTMPVVTS 2235
Query: 460 KNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR------SRSRTP-TKRGHSRSRSPQ 512
+ + D S T S + SP TA+ S TP T S +
Sbjct: 2236 EASTLSATPVDTSTPVTTSTEA--TSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVAN 2293
Query: 513 WRRSRSAQRWGRSRSP---QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT 569
S + S +P S P G S +T G + R S + +
Sbjct: 2294 SEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASF 2353
Query: 570 RGRSRSRTPARRGRSRSRTPARRRSRS-RTPTRRRSRSRTPARRGRSRSRTPARRRSRTR 628
+ S TPA + TP S++ +PT S P S
Sbjct: 2354 ETSTLSTTPAD-----TSTPVTTYSQAGSSPTTADDTSM------------PTSTYSEGS 2396
Query: 629 SPVRRRSRSRSPARRSGRS-RSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687
+P+ S P S S S TP + TP S +P G S +P
Sbjct: 2397 TPLTSVPVSTMPVVSSEASTHSTTPVD-----TSTPVTTSTEASSSPTTAEGTSIPTSPP 2451
Query: 688 RRGRSR------SRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS-----RT 736
G + S TP S + + TP SSS + T
Sbjct: 2452 SEGTTPLASMPVSTTPVV--SSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIST 2509
Query: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS--------PCPKQ 788
+ S +S + + ++S + +LS+ + S + +S S+ P
Sbjct: 2510 ASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTY 2569
Query: 789 KSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT 848
+ P RS S++P A S S+ S P S + + +SSSP +
Sbjct: 2570 SEGSTPLRSMPVSTKPLASSEA------STLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623
Query: 849 P---PRQ--GSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST 903
P P + S+TS + V S ++P T S + + SSP + S+
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTS--TGTSSSPTTAEGSS 2681
Query: 904 PPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRL 963
P +P S+P + + S + + S +P ++ T S SP + E
Sbjct: 2682 MPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSP-TTAEGTS 2740
Query: 964 LPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKD 1023
+ + S S+P T + T P S S V P S S SP E +
Sbjct: 2741 MRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVT-- 2798
Query: 1024 SLVQSCPGSLS--LCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS 1081
S+ S P S L + + TP S G S T+P DTS+P + +
Sbjct: 2799 SMPTSTPSETSTPLTSMPVNHTPVASSEAGTLS--------TTP---VDTSTPVTTSTKA 2847
Query: 1082 ESPSLQSKSQTSPKGGRSRSSSPVTEL-ASRSPIRQDRGE-FSASPMLKSGMSPEQSRFQ 1139
S ++ P S S+ +T + S +P+ S +P+
Sbjct: 2848 SSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPV------------- 2894
Query: 1140 SDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESS 1199
+S P S G S TAE P E +T P S PV S+
Sbjct: 2895 --DTSIPVTTSTE--GSSSPTTAEGTSMPISTPSEVST---PLTSILVSTVPVAGSEAST 2947
Query: 1200 LVFKDT-LRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSS 1258
L RTP + A SSP T E S +P S+ E + S + SS
Sbjct: 2948 LSTTPVDTRTPVTTSAEASSSPTTAEGTS-MPISTPGERRTPLTSMSVST----MPVASS 3002
Query: 1259 ELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGG----------- 1307
E +S + ++S V + + + S S + E +P S G
Sbjct: 3003 EASTLSRTPADTSTPV------TTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTT 3056
Query: 1308 PHFSPEHKELSNSPLRENSFGSPLEFRNSGPL---GTEMNTGFSSEVKEDLNG------- 1357
P PE LS +P+ NS +S P GT M SE L G
Sbjct: 3057 PVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTP 3116
Query: 1358 ---PFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGM-SSNQSISSPVLDAVPRT 1413
++ L T P +T + HSS P E M +S S S L +P +
Sbjct: 3117 VTSSAISTLSTTPVDTSTPVTTSTEAHSS----PTTSEGTSMPTSTPSEGSTPLTYMPVS 3172
Query: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473
SS S+ TP S +S +G+ P+ TP
Sbjct: 3173 TMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTS---------------TP 3217
Query: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL 1533
S G + S P P S ++P +N LT E S S + + ++ +
Sbjct: 3218 SEGMTPLTSVPVSNT-PVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTP 3276
Query: 1534 GQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSP 1593
+ S +S + AS SE+ + + A T TP+ S++ SSP + + +
Sbjct: 3277 SEGSTPLTSMPVSTTTVAS----SETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPT 3332
Query: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
GS+P P S ++S P + P + + +S + EG+S
Sbjct: 3333 STYSEGSTPLTNMSFSTTPVVSS--EASTLSTTPVDTSTPVTTSTEASLSPT--TAEGTS 3388
Query: 1654 STESSPEH---PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
SSP P S S E T S TP + L S A
Sbjct: 3389 IPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNT------------LVTTSTEA 3436
Query: 1711 SSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGL 1770
SSSP T S T TTS S P L
Sbjct: 3437 SSSPTIAEGT-----------------------------SLPTSTTSEGSTPLSIMP--L 3465
Query: 1771 QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES 1830
+ S T +T D S + +TS S + + VT +G S
Sbjct: 3466 STTPVASSEASTLSTTPVDTS-TPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPV 3524
Query: 1831 SRT--SSRRRRGRSRTPPTSR----KRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
S T +S S TP S S++ +SPA + + R S + S T L+S
Sbjct: 3525 STTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLS 3584
Query: 1885 RR--RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP-----PVTRRRSRS 1937
S ++P + RS T +S S +P TP P+T +
Sbjct: 3585 STYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVST 3644
Query: 1938 RTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSR 1997
+ T + T PV + TP +T + S SP+T + + +
Sbjct: 3645 TSVTISEAGTASTLPVD-----TSTPVITSTQVSS--SPVTPEGTTMPIWTPSEGSTPLT 3697
Query: 1998 TSPV-TRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRS 2056
T PV T R + S S ++ + TP + S + L P+ I +
Sbjct: 3698 TMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTT 3757
Query: 2057 RTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSC 2116
T R S P+I S S + S ++ P T G+ T P++ S R +
Sbjct: 3758 ILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLE--GTTTMPMSTTSERSTL 3815
Query: 2117 FSRPSMSP-TPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN 2175
+ +SP + + + + P G + TP+ +AG + I R S+
Sbjct: 3816 LTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTI----RISIT-- 3869
Query: 2176 HAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235
S + LT + + T P + P A++AS P
Sbjct: 3870 ---SERSTPLTTLLVSTTLPT-------------------------SFPGASIASTPPLD 3901
Query: 2236 SAAAMNLAS--ARTPAIPTAVNLADSR-TPAAAAAMNLASPRTAVAPSAVNLADPRTP-- 2290
++ ++ A TP IP A ++ S T + + P T V S ++ T
Sbjct: 3902 TSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAV 3961
Query: 2291 TAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPV 2350
+ P + TP+ ++ + T T + + + T AP + V +A +T
Sbjct: 3962 STPVITSTELNTPSTSSSSTTTSFST---TKEFTTPAMTTAAPLT--YVTMSTAPSTPRT 4016
Query: 2351 NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYER---VSGRTSPPLLDRARS 2407
G T+A S SA P S + T P P S R ++ T PP A S
Sbjct: 4017 TSRGCTTSA-----STLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHS 4071
Query: 2408 RTPPSAPSQSRMTSERA-------PSPSSRMGQAPS 2436
TPP+ + S + A PS+R P+
Sbjct: 4072 STPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPT 4107
Score = 135 bits (340), Expect = 6e-31
Identities = 383/1741 (21%), Positives = 598/1741 (34%), Gaps = 250/1741 (14%)
Query: 250 STTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALA---GRSPSPASGRRGEG 306
STTP + ST S+++S S S ++ T + P +S
Sbjct: 2536 STTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLS 2595
Query: 307 DAPF--SEPGTTSTQRPSSPETA--TKQP-SSPYEDKDKDKKEKSATRPSPSPERSSTGP 361
P S P TTST+ SSP TA T P S+P E +T P S E S+
Sbjct: 2596 TTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLST 2655
Query: 362 EPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESS 421
P L+ G S P T S P + P E S + +S+ S+
Sbjct: 2656 TPVDTRTLVTTSTGTSSSP-TTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST 2714
Query: 422 PP--SPQPTKVSRHASSSP----------ESPKPAPAPGSHREISSSPTSKNRSHGRAKR 469
P + P S ASSSP +P P + +S+ P + + + +
Sbjct: 2715 TPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTT 2774
Query: 470 DKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQ 529
S + S SP TA+ + TP++ + P ++ G
Sbjct: 2775 AVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTL---- 2830
Query: 530 RRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSR------SRTPARRGR 583
S +P + +T + S + G S A+ G + S TP
Sbjct: 2831 ----STTPVDTSTPVTTST-KASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSE 2885
Query: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARR 643
+ + + + T S G S P S +P+ S P
Sbjct: 2886 ASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSM---PISTPSEVSTPLTSILVSTVPVAG 2942
Query: 644 SGRSR-SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRS-RTPARRGRSRSRTPRRGR 701
S S S TP +RTP S +P G S TP R RTP
Sbjct: 2943 SEASTLSTTPVD-----TRTPVTTSAEASSSPTTAEGTSMPISTPGER-----RTPLTSM 2992
Query: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761
S S V +SSE SRT S+P + SS
Sbjct: 2993 SVSTMPV-----------------ASSEASTLSRTPA----DTSTPVTTSTEASS----- 3026
Query: 762 LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGS--SQPKAKSRTPPRRSRS-S 818
SP + + + + GS+P T P S S S +P S S
Sbjct: 3027 --SPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVS 3084
Query: 819 SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878
SSP P + + P S+P V T P +TS + S TP
Sbjct: 3085 SSPTPAEGTSMPISTYSEGSTPLTGVPVSTTP----VTSSAISTLSTTP----------- 3129
Query: 879 PELKSRTPSRHSCSGSSPPRVKSSTP-PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937
+ + TP S S P T P +PS S+P + +S S S+ S
Sbjct: 3130 --VDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP--VSTMLVVSSEDSTLS 3185
Query: 938 PSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP 997
+ V + T S + + E +P + S +P T V P S SI
Sbjct: 3186 ATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTT 3245
Query: 998 KVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQL 1057
V + TP S S SP E + GS L + S+T S S
Sbjct: 3246 PVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTP 3305
Query: 1058 KGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQD 1117
S + +SSP + S P S S+P+T ++
Sbjct: 3306 ADTSTPVTTYSQASSSPPIADGTS-----------MPTSTYSEGSTPLTNMS-------- 3346
Query: 1118 RGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDAT 1177
FS +P++ S S S D+S+ T + + L + + E ++P T
Sbjct: 3347 ---FSTTPVVSSEAS-TLSTTPVDTSTPVTTSTEASLSPT------TAEGTSIP-----T 3391
Query: 1178 ASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRE------RSGAGSSPETKEQNSALPT 1231
+SP + PV P S +TL T P + S SS T + ++LPT
Sbjct: 3392 SSPSEGTTPLASMPVSTTPVVSSEV-NTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPT 3450
Query: 1232 S--SQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQS 1289
S S+ + ++ S P SSE +ST+ ++S V S +
Sbjct: 3451 STTSEGSTPLSIMPLSTTPVA------SSEASTLSTTPVDTSTPV---------TTSSPT 3495
Query: 1290 QASLEAVEVPSMASSWGG--------------PHFSPEHKELSNSPLRENSFGSPLEFRN 1335
+S EV SM +S G P S E LS +P+ N+F + +
Sbjct: 3496 NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQAS 3555
Query: 1336 SGPLGTEMNT--------GFSSEVKEDLNGPFLNQLE-TDPSLDMKEQST--RSSGHSSS 1384
S P ++ T G SS L+ ++ E + PS ++ST +S S+S
Sbjct: 3556 SSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNS 3615
Query: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
+P V MS+ +S+P+ T S S + ++ + ++ SS
Sbjct: 3616 TPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSS 3675
Query: 1445 PGLRDGSGTPSRHSLSGSSPGMKDIPRTPSR-GRSECDSSPEPKALPQTPRPRSRSPSSP 1503
P +G+ P GS+P + +P + +R SE + P + TP S S
Sbjct: 3676 PVTPEGTTMPIWTPSEGSTP-LTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISS 3734
Query: 1504 ELNNKCLTPQRERSGSESSVDQK-TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSS 1562
T S++ V+ TP+ + S + V S S SE SS
Sbjct: 3735 SATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSS 3794
Query: 1563 PDSKAKTRT----PLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGS 1618
P + T T +RS ++ + S +SP + + S+P ++GS
Sbjct: 3795 PTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGS 3854
Query: 1619 DSSP------------EPKAP---------APRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
S P E P P + P S + + + S+ T S
Sbjct: 3855 FSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTAS 3914
Query: 1658 SPEHPPKSRTA----RRGSR--------SSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
+P P + + GS S+P + + P + S+P +T
Sbjct: 3915 TPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVIT---STEL 3971
Query: 1706 RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP 1765
+ S SSS T S + + +P++++ P S ++P T T+ RG + S
Sbjct: 3972 NTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMS------TAPSTPRTTSRGCTTSA 4025
Query: 1766 KPRGLQRSRSRSRREKTR-TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
+ S TR T + S S TS + + HS +
Sbjct: 4026 STLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPA------------HSST 4073
Query: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
P +S T+ + T T+R + +RT+ P + + + T + + + TP +
Sbjct: 4074 PPTTSASSTTV---NPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVP 4130
Query: 1885 R 1885
R
Sbjct: 4131 R 4131
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 219 bits (558), Expect = 3e-56
Identities = 218/690 (31%), Positives = 297/690 (43%), Gaps = 80/690 (11%)
Query: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR 1597
+ S + + PS S ++ P S T++ RS + P S +SP S+
Sbjct: 5 KRSSKPSMSLAPSGSSMPTADP-KPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSK 63
Query: 1598 SGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
S S K P P ++S S KA P + +R+ +SK T S
Sbjct: 64 STKSTSTKRAPSNRPSSRSRVRS----KARTPSRVSTDTRTSKASKASDVRCHQRRGTHS 119
Query: 1658 SPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS------ 1711
P RRGSRSS +++ TP R R+ + P + + R + S
Sbjct: 120 RGRTP-----GRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYG 174
Query: 1712 ---SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS---RRGRSPSP 1765
+S RS + PR+ S P + RSS + S+ + +T + + +S +P
Sbjct: 175 RPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP 234
Query: 1766 KPRGLQRSRSR------SRREKTRTTRRRDRSGS-SQSTSRRRQRSRSRSRVTRRRRGGS 1818
P ++ +S SR + T R S +Q+++R R +S S+SR RR R GS
Sbjct: 235 SPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGS 294
Query: 1819 GYHSRSPARQES-----SRTSSRRRRG---------------------RSRTPPTSRKRS 1852
+ S R S SR SR R+G +SRTP R +
Sbjct: 295 QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHN 354
Query: 1853 RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT-SVTRRRS 1911
SR S SR+S S +P RS+S + R SRSR+ + R RS
Sbjct: 355 WSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS 414
Query: 1912 RSRASPVSRRRSRSRTPPVTRRRSRSRTP-TTRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970
RSR+ +R RSRSR+P R SRSR+P R RSRSR+P R SRSR+P R RS
Sbjct: 415 RSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRS 474
Query: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR-SRTSPVTRRRSRSRTPPAIRRR 2029
RSR SP R SP R R SP R+ R SR+S R RSR+P R+R
Sbjct: 475 RSR-SPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQR 533
Query: 2030 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSS---D 2086
+SR+P R RS+SRSP R +SR+P R +R RSP R R S SSS D
Sbjct: 534 RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRR-WRSPSKERERRQSRSSSEERD 592
Query: 2087 RSRSATP------------PATRNHSGSRTPPVALNSSRMSCFSR---PSMSPTPL--DR 2129
SRS +P + HS SRTP N S+ S+ PS S P D
Sbjct: 593 HSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDW 652
Query: 2130 CRSPGMLEPLGSSRTPMSVLQQAGGSMMDG 2159
RSP L +RTP + + G
Sbjct: 653 KRSPTRTSSLSQNRTPSKTSSHSPSTFPSG 682
Score = 219 bits (557), Expect = 4e-56
Identities = 227/750 (30%), Positives = 346/750 (46%), Gaps = 90/750 (12%)
Query: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSP--------TPKSKRKSKDKKRKRSRST 251
S SS P + K + K +S + ++ P +P S + +K KR+ S
Sbjct: 17 SGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSN 76
Query: 252 TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT---TALAGRSPSPASGRRGEGDA 308
P+ +SR ++ + S+ + S+++ + H T GR+P GRRG
Sbjct: 77 RPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTP----GRRG---- 128
Query: 309 PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368
S S R S+P + P S R S ++ S G P
Sbjct: 129 --SRSSKRSPSRASTPGRIRTHGARP--------GMASRVRTPTSQQKGSRGKSYGRPRT 178
Query: 369 LLAERHGGSPQPLATT---PLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
ER P+ L+ P + SE + T + ++P +P S++ PS
Sbjct: 179 SNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSS 238
Query: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485
KV + S + + +P E+SS S N++ R+ R +SHS +SR
Sbjct: 239 S-RKVKSYGQMIIPSREKSYSP---TEMSSRVKSYNQASTRS-RPQSHS--------QSR 285
Query: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545
SP +R RS S+ KR HSR RS W+R+ S R+RS R+G R SRS
Sbjct: 286 SP---RRSRSGSQ---KRTHSRVRSHSWKRNHS-----RARSRTRKGILSQMGRHSQSRS 334
Query: 546 RNTQR-RGRSRSARRGRSH--SRSPAT-RGRSRSRTPARRGRSRSRTPARR---RSRSRT 598
+ + + +SR+ RRGRSH SR+P+ R S SR+ ++ R + R+ RS+S +
Sbjct: 335 HSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS 394
Query: 599 PTRRR--SRSRTPAR-RGRSRSRTP--ARRRSRTRSPVRRR--SRSRSPARRSGRSRSRT 651
P ++R SRSR+P + R RSRSR+P AR RSR+RSP + R SRSRSP + RSRSR+
Sbjct: 395 PNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRS 454
Query: 652 PAR-RGRSRSRTPAR-RGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLV 708
P + R SRSR+P + R RSRSR+P++ S+ +P++ R RSR+P + R
Sbjct: 455 PNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ-----C 509
Query: 709 RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK 768
R+ RS S+ R S ER+ + S + R S R+SRS S R +
Sbjct: 510 RQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR 569
Query: 769 AKSR-----LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPP 823
+ R R+S S S +S++P +SG S+P+A S+ ++ S S P
Sbjct: 570 RRWRSPSKERERRQSRSSSEERDHSRSRSP--NKQSGYSRPRASSK---EKAHSRSRTPS 624
Query: 824 KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS 883
K+ + + SR S S P +P + S T + Q+ TP + S S P
Sbjct: 625 KEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPS-GG 683
Query: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSS 913
+T S+ S + K++ P +S S SS
Sbjct: 684 QTLSQDD-SQADATTSKATLPGERSSSSSS 712
Score = 212 bits (540), Expect = 4e-54
Identities = 219/732 (29%), Positives = 331/732 (45%), Gaps = 90/732 (12%)
Query: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR 219
+ P +P P SL S++S TP + K R S S + KS+ K+
Sbjct: 19 SSMPTADPKPPASL----KSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAP 74
Query: 220 SESESKKRKHRSPTPKSKRKSKDKKR-KRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
S S + + RS R S D + K S+++ RR S S R
Sbjct: 75 SNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKR 134
Query: 279 SRSAAA-----KTHTT--ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS-PETATKQ 330
S S A+ +TH +A R +P S ++G + P T++ +R S P +K+
Sbjct: 135 SPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKK 194
Query: 331 PSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP 390
P + + A PS + ++ TG + ++ +P P + S++
Sbjct: 195 SYRPPGGSGIGRSSELAVTPSTAKCQTPTG--------IPSKEKSDNPSPSS----SRKV 242
Query: 391 VNPPSEASPTRDRS-PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
+ P+R++S P +S + S+ PQ S S SP + +
Sbjct: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQ----SHSQSRSPRRSRSGSQKRT 298
Query: 450 HREISSSPTSKNRSHGRAKRDKS-------HSHTPSRRMGRSRSPA-TAKRGRSR--SRT 499
H + S +N S R++ K HS + S G+S++ + T +RGRS SR
Sbjct: 299 HSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRN 358
Query: 500 PTK-RGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR 558
P+K R HS SRS S+ G S + GRS+S G + R RS +
Sbjct: 359 PSKERSHSHSRSS----SKERDHRGSSSPRKESGRSQS----GSPNKQRDHSRSRSPNKA 410
Query: 559 RGRSHSRSP-ATRGRSRSRTPAR-RGRSRSRTP--ARRRSRSRTPTRRR--SRSRTPAR- 611
R RS SRSP R RSRSR+P + R SRSR+P AR RSRSR+P + R SRSR+P +
Sbjct: 411 RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKA 470
Query: 612 RGRSRSRTPARRRSRTR--SPVRRRS--RSRSPARRSGRSRSRTPAR-RGRSRSRTPAR- 665
R RSRSR+P++ R ++ SP + R RSRSP++ +SR+ ++ R RSR+P++
Sbjct: 471 RDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKE 530
Query: 666 RGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
R R +SR+P + RS+SR+P+ R +SR+P + R R RR RS S+ +RR
Sbjct: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR-----RRWRSPSKERERRQSR 585
Query: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
SS ER + S + S P + RSR+ S + ++SR S + S S
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
Query: 785 CPKQKS-QTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK----------------QKS 827
P+ + P R+ S S ++RTP + S S S P K+
Sbjct: 646 VPRSPDWKRSPTRTSSLS-----QNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700
Query: 828 KTPSRQSHSSSS 839
P +S SSSS
Sbjct: 701 TLPGERSSSSSS 712
Score = 183 bits (464), Expect = 2e-45
Identities = 199/644 (30%), Positives = 290/644 (45%), Gaps = 67/644 (10%)
Query: 1371 MKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDG 1430
M S++S+ +S++ +P SN+ S + + RTPSR + + +S K
Sbjct: 57 MSPSSSKSTKSTSTKRAP---------SNRPSSRSRVRSKARTPSRVSTDTRTSKASKAS 107
Query: 1431 LPRTPSRRSRS--GSSPGLRDG---------SGTPSRHSLSGSSPGMKDIPRTPSRGRSE 1479
R RR G +PG R + TP R G+ PGM RTP+ +
Sbjct: 108 DVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQK- 166
Query: 1480 CDSSPEPKALPQTPRPRSRSPSSPE-LNNKCLTPQRERS---GSESSVDQKTV-ARTPLG 1534
S + P+T R RS S P L+ K P SE +V T +TP G
Sbjct: 167 -GSRGKSYGRPRTSN-RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTG 224
Query: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSR--------SGSSPEVD 1586
S+ S PS+S + +S S+ K+ +P SR + S P+
Sbjct: 225 IPSKEKSDNP---SPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
Query: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
S+SR SPRRSRSGS + R+ ++ S + + + R S+S S SKG+
Sbjct: 282 SQSR-SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKS 340
Query: 1647 PSPEGSSSTESS---PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
+ + S +P K R+ SS E + + PR+ S RS K R
Sbjct: 341 QNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD 400
Query: 1704 SRRSRSASSSPE-TRSRTPPRHR---RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR- 1758
RSRS + + + +RSR+P + R RS S + +SRS + R S R+ +R
Sbjct: 401 HSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARD 460
Query: 1759 --RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSG-SSQSTSRRRQRSRSRSRVTRRRR 1815
R RSP+ + RSRSRS ++ RD S S S R +RSRS S+ + R+
Sbjct: 461 HSRSRSPN---KARDRSRSRS------PSKERDHSQLGSPSKERDHRRSRSPSKERQCRQ 511
Query: 1816 GGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR- 1874
S R R S S R+R +SR+P R RS+SR SP+ + R SP+ R
Sbjct: 512 SRSSSKERDHRRSRSP--SKERQRRQSRSPNKERDRSQSR-SPSEEREHRQSRSPSKERD 568
Query: 1875 RSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR-SRSRASPVSRRRSRSRTPPVTRR 1933
R R R+P R R +SR+S R SRSR+ + SR RAS + SRSRTP
Sbjct: 569 RRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGN 628
Query: 1934 RSRSRTPTTRRRSRSRTPPVTR--RRSRSRTPPVTRRRSRSRTS 1975
S+SRT + T P + +RS +RT +++ R+ S+TS
Sbjct: 629 HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTS 672
Score = 164 bits (414), Expect = 1e-39
Identities = 205/720 (28%), Positives = 320/720 (44%), Gaps = 81/720 (11%)
Query: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452
P + PT D PP S + ++ + S P+ T SR++ SP S K + + R
Sbjct: 16 PSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPAT--SRNSVMSPSSSKSTKSTSTKRA 73
Query: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG-HSRSRSP 511
S+ P+S++R +A+ TPSR +R+ +K S R +RG HSR R+P
Sbjct: 74 PSNRPSSRSRVRSKAR-------TPSRVSTDTRTSKASKA--SDVRCHQRRGTHSRGRTP 124
Query: 512 QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS---RSRNTQRRG-------RSRSARRGR 561
R SRS++R S R R+ RPG + R+ +Q++G R R++ R R
Sbjct: 125 GRRGSRSSKRSPSRASTPGRIRTHGA-RPGMASRVRTPTSQQKGSRGKSYGRPRTSNRER 183
Query: 562 SHSRSPATRGRSRSRTPARRGRSRSR----TPARRRSRSRT--PTRRRSRSRTPARR--- 612
S S+ P + R P G RS TP+ + ++ T P++ +S + +P+
Sbjct: 184 SDSQ-PRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKV 242
Query: 613 ---------GRSRSRTPARRRSR--------TRSPVRRRSRSRSPARRSGRSRSRTPAR- 654
R +S +P SR TRS + S+SRSP R S+ RT +R
Sbjct: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRV 302
Query: 655 RGRSRSRTPAR-RGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSL---VR 709
R S R +R R R+R ++ S+SR+ ++ + +++SRTPRRGRS + S
Sbjct: 303 RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKE 362
Query: 710 RGRSHSRTPQR-RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK 768
R SHSR+ + R GSSS RK R SQ S + + + R RS S K
Sbjct: 363 RSHSHSRSSSKERDHRGSSSPRKESGR-SQSGSPNKQRDHSRSRSPNKARDRSRSRSPYK 421
Query: 769 AKSRLSLRRSLSGSSPCPKQKSQTPPR-RSRSGS---SQPKAKSRTPPR-RSRSSSSPPP 823
A+ R S RS + + C + +S R RSRS S ++ ++SR+P + R RS S P
Sbjct: 422 ARDR-SRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480
Query: 824 KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS 883
K++ + S S H + +S + RQ + + E+ RRS S +S
Sbjct: 481 KERDHS-QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD---HRRSRSPSKERQRRQS 536
Query: 884 RTPSRH-SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVT 942
R+P++ S S P + +SPS+ + + ++ R+R S SSS
Sbjct: 537 RSPNKERDRSQSRSPSEEREHRQSRSPSKERDRR-RWRSPSKERERRQSRSSSEERDHSR 595
Query: 943 SRTTPRRSRSVSPCSNVESRLLPRY---SHSGSSSPDTKVKPETPPRQSHSGSISPYPKV 999
SR+ ++S P ++ + + R S G+ S E+ P QS ++ P
Sbjct: 596 SRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS---TVPRSPDW 652
Query: 1000 KAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLS-----LCAGVKSSTPPGESYFGVSS 1054
K SLS +++P S S +LS A +T PGE SS
Sbjct: 653 KRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 154 bits (389), Expect = 1e-36
Identities = 206/738 (27%), Positives = 319/738 (43%), Gaps = 139/738 (18%)
Query: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS 456
+SP R P S P SS ++ P P P + S++P P + R S
Sbjct: 2 SSPKRSSKPSMS--LAPSGSSMPTADPKP-PASLKSTKSATPNRSLVPTKPATSRNSVMS 58
Query: 457 PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT--------------- 501
P+S ++ + S PS R P++ R RS++RTP+
Sbjct: 59 PSSS-----KSTKSTSTKRAPSNR------PSSRSRVRSKARTPSRVSTDTRTSKASKAS 107
Query: 502 ------KRG-HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS---RSRNTQRR 551
+RG HSR R+P R SRS++R S R R+ RPG + R+ +Q++
Sbjct: 108 DVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHG-ARPGMASRVRTPTSQQK 166
Query: 552 -------GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSR----TPARRRSRSRT-- 598
GR R++ R RS S+ P + R P G RS TP+ + ++ T
Sbjct: 167 GSRGKSYGRPRTSNRERSDSQ-PRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGI 225
Query: 599 PTRRRSRSRTPARR------------GRSRSRTPARRRSR--------TRSPVRRRSRSR 638
P++ +S + +P+ R +S +P SR TRS + S+SR
Sbjct: 226 PSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR 285
Query: 639 SPARRSGRSRSRTPAR-RGRSRSRTPAR-RGRSRSRTPARRSGRSRSRTPAR-RGRSRSR 695
SP R S+ RT +R R S R +R R R+R ++ S+SR+ ++ + +++SR
Sbjct: 286 SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR 345
Query: 696 TPRRGRSRSRS---LVRRGRSHSRTPQR-RGRSGSSSERKNKSRT------SQRRSRSNS 745
TPRRGRS + S R SHSR+ + R GSSS RK R+ QR +
Sbjct: 346 TPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSR 405
Query: 746 SPEMKKSRISSR---RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR-----RS 797
SP + R SR ++R S RS K+R RS S + +S++P + RS
Sbjct: 406 SPNKARDRSRSRSPYKARDRSRSRSPNKAR-DCSRSRSPYKARDRSRSRSPNKARDHSRS 464
Query: 798 RS-GSSQPKAKSRTPPR-RSRSSSSPPPKQ----KSKTPS-----RQSHSSSSPHPKVKS 846
RS ++ +++SR+P + R S P K+ +S++PS RQS SSS +S
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS 524
Query: 847 GTPPRQGS-ITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP 905
+P ++ S N++ Q RS E + +S + R SP + +
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQS 584
Query: 906 RQSP-----SRSSSPQPK---VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCS 957
R S SRS SP + + S ++++HS S +PS S +SR+ S S
Sbjct: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHS-----QSRTSSKES 639
Query: 958 NVESRLLPRYSHSGSSSPDTKVKP--------ETPPRQSHSGSISPYP---KVKAQTPPG 1006
+ +PR SPD K P P ++ S S S +P + +Q
Sbjct: 640 DPSQSTVPR-------SPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692
Query: 1007 PSLSGSKSPCPQEKSKDS 1024
+ SK+ P E+S S
Sbjct: 693 ADATTSKATLPGERSSSS 710
Score = 130 bits (327), Expect = 2e-29
Identities = 223/821 (27%), Positives = 323/821 (39%), Gaps = 141/821 (17%)
Query: 1132 SPEQSRFQSDS-----SSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDK 1186
SP++S S S SS PT D A K + P + P
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKP--------PASLKSTKSATPNRSLVPTKPATSRN 54
Query: 1187 FSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEV---VE 1243
P + S K P RS S T + S +S+ + +V
Sbjct: 55 SVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQR 114
Query: 1244 KSEEPAGQILSHLSSELKEMSTSNFESSPEVEE---RPAVSLTLDQSQSQASLEAVEVPS 1300
+ G+ S + S S + + RP ++ + SQ + S
Sbjct: 115 RGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQ------QKGS 168
Query: 1301 MASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFL 1360
S+G P S ++E S+S R S S +R G G G SSE+ P
Sbjct: 169 RGKSYGRPRTS--NRERSDSQPRNLSKKS---YRPPGGSGI----GRSSELAVT---PST 216
Query: 1361 NQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSS 1420
+ +T + KE+S S SS ++ S Q I PSRE+S
Sbjct: 217 AKCQTPTGIPSKEKSDNPSPSSSRKVK---------SYGQMI----------IPSREKSY 257
Query: 1421 SASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS--RGRS 1478
S + + S RSR P S +P R S SGS R+ S R S
Sbjct: 258 SPTEMSSRVKSYNQASTRSR----PQSHSQSRSP-RRSRSGSQKRTHSRVRSHSWKRNHS 312
Query: 1479 ECDSSPEPKALPQTPR-PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537
S L Q R +SRS S + N+ TP+R RS + S R P +RS
Sbjct: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWS--------RNPSKERS 364
Query: 1538 RS---GSSQELDVKPSASPQERS--ESDSSPDSK---AKTRTP--LRQRSRSGSSPEVDS 1587
S SS+E D + S+SP++ S SP+ + +++R+P R RSRS S +
Sbjct: 365 HSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARD 424
Query: 1588 KSRL-SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
+SR SP ++R S K R R++S + + ++ +P RSRS S SK R
Sbjct: 425 RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERD 484
Query: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRR 1706
S GS P K R RR SR+P + R R S + K R RR
Sbjct: 485 HSQLGS---------PSKERDHRR-----------SRSPSKERQCRQSRS-SSKERDHRR 523
Query: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
SRS S + R P R S S P+E+ R R + SP + RR RSPS +
Sbjct: 524 SRSPSKERQRRQSRSPNKERDRS-QSRSPSEE----REHRQSRSPSKERDRRRWRSPSKE 578
Query: 1767 PRGLQRSRSRSRREKTRTTRRRD---RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR 1823
+R +SRS E+ +R R +SG S+ + ++++ SRSR + G HS+
Sbjct: 579 R---ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSK----EGNHSQ 631
Query: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLI 1883
SRTSS+ T P S WKRS +R S + R+ S+T
Sbjct: 632 -------SRTSSKESDPSQSTVPRS----------PDWKRSPTRTSSLSQNRTPSKTSSH 674
Query: 1884 SRRRSRSRTSPVSRRRSR-----SRTSVTRRRSRSRASPVS 1919
S S +S+ S+ S+ ++ RS S +S ++
Sbjct: 675 SPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKLA 715
Score = 129 bits (323), Expect = 5e-29
Identities = 154/539 (28%), Positives = 230/539 (42%), Gaps = 95/539 (17%)
Query: 165 PEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESES 224
P K YS SS +S + + + S+S SPRR R S K+ R S S
Sbjct: 251 PSREKSYSPTEMSSRVKSYNQASTRSRPQS----HSQSRSPRRSRSGSQKRTHSRVRSHS 306
Query: 225 KKRKH---RSPTPK---------SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS 272
KR H RS T K S+ +S K + +++S TP R RS + S
Sbjct: 307 WKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTP-----RRGRSHNWSRNPSK 361
Query: 273 DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPS 332
+ S S SRS++ + + SP SGR G +P + + ++ P+ ++
Sbjct: 362 ERSHSHSRSSSKERDHRGSS--SPRKESGRSQSG-SPNKQRDHSRSRSPNKARDRSRS-R 417
Query: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
SPY+ +D+ + S SP ++ +P SP S+ P
Sbjct: 418 SPYKARDRSR--------SRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP-- 467
Query: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452
+ RDRS +SP K S S P+K H S +P R+
Sbjct: 468 -----NKARDRSRSRSPSKERDHSQLGS------PSKERDHRRSR--------SPSKERQ 508
Query: 453 ISSS-PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTK-RGHSRSRS 510
S +SK R H R S S + R+ +SRSP +R RS+SR+P++ R H +SRS
Sbjct: 509 CRQSRSSSKERDHRR-----SRSPSKERQRRQSRSP-NKERDRSQSRSPSEEREHRQSRS 562
Query: 511 PQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATR 570
P R R RR RS S +R +R+ RS S R S SRSP +
Sbjct: 563 PSKERDR------------RRWRSPSKER--------ERRQSRSSSEERDHSRSRSPNKQ 602
Query: 571 -GRSRSRTPAR-RGRSRSRTPAR--RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR 626
G SR R ++ + SRSRTP++ S+SRT ++ S++ R R+P R S
Sbjct: 603 SGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSS- 661
Query: 627 TRSPVRRRSRSRSPARRSGRSRSRTPA-RRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
S++R+P++ S S S P+ + S+ + A S++ P RS S S+
Sbjct: 662 -------LSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
Score = 106 bits (264), Expect = 4e-22
Identities = 188/773 (24%), Positives = 282/773 (36%), Gaps = 103/773 (13%)
Query: 1054 SLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSP 1113
SL G S + D + S + + + +K TS S SSS T+ S
Sbjct: 13 SLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKR 72
Query: 1114 IRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQ 1173
+R S S + +P SR +D+ + ++ + R T
Sbjct: 73 APSNRPS-SRSRVRSKARTP--SRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGS 129
Query: 1174 EDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSS 1233
+ SP R RP + +RTP ++ G+ + + S S
Sbjct: 130 RSSKRSPSRASTPGRIRTHGARPGMA----SRVRTPTSQQKGSRGKSYGRPRTSNRERS- 184
Query: 1234 QDEELMEVVEKSEEPAGQILSHLSSELKEM-STSNFES-----SPEVEERPAVSLTLDQS 1287
D + + +KS P G SSEL ST+ ++ S E + P+ S S
Sbjct: 185 -DSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPS----SS 239
Query: 1288 QSQASLEAVEVPSMASSWGGPHFSPEHKELSNS-----PLRENSFGSPLEFRNSGPLGTE 1342
+ S + +PS S+ S K + + P + SP R+ T
Sbjct: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTH 299
Query: 1343 MNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQS-TRSSGHSSSELSPDAVEKAGMSSNQS 1401
S + + + QS + S G S ++ + G S N S
Sbjct: 300 SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQ---SRTPRRGRSHNWS 356
Query: 1402 ISSPVLDAVPRTPSRERSSSASSPEMKD------GLPRTPSRRSRSGSSPGLRDGSGTPS 1455
R PS+ERS S S K+ PR S RS+SGS RD
Sbjct: 357 ----------RNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD------ 400
Query: 1456 RHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRE 1515
HS S R+P++ R R RSRSP ++ +P +
Sbjct: 401 -HSRS----------RSPNKARD---------------RSRSRSPYKARDRSRSRSPNKA 434
Query: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQ 1575
R S S R+P R RS S A RS S + ++++R+P ++
Sbjct: 435 RDCSRS--------RSPYKARDRSRSRSP----NKARDHSRSRSPNKARDRSRSRSPSKE 482
Query: 1576 RSRS---GSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL 1632
R S S E D + SP + R K R R++S S ++ +P
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 1633 PRRSRSGSSSKGRGPSPEGSSSTESSPEH--PPKSRTARRGSRSSPEPKTKSRT-PPRRR 1689
RS+S S S+ R S S E P RR SRSS E + SR+ P ++
Sbjct: 543 RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQ 602
Query: 1690 SSRSSPELTRKARLSRRSRSASSSPE-TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
S S P + K + RSR+ S ++SRT + + P + RS R S
Sbjct: 603 SGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSL 662
Query: 1749 SSPRT--KTTSRRGRSPSPKPRG---LQRSRSRSRREKTRTTRRRDRSGSSQS 1796
S RT KT+S SPS P G L + S++ ++ T +RS SS S
Sbjct: 663 SQNRTPSKTSSH---SPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 99.8 bits (247), Expect = 3e-20
Identities = 204/846 (24%), Positives = 305/846 (36%), Gaps = 180/846 (21%)
Query: 1924 RSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSR 1983
RS P ++ S S PT + PP + + ++S TP RS T P T
Sbjct: 6 RSSKPSMSLAPSGSSMPTADPK-----PPASLKSTKSATP----NRSLVPTKPAT----- 51
Query: 1984 SRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR 2043
SR S ++ S+S S T+R +R S +R RS++RTP SR T K S+
Sbjct: 52 SRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTP------SRVSTDTRTSKASK 105
Query: 2044 SRSPLAIRRR---SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS 2100
+ +RR SR RTP RG RS RSP SR++TP R H
Sbjct: 106 ASDVRCHQRRGTHSRGRTPGR-RGSRSSKRSP---------------SRASTPGRIRTH- 148
Query: 2101 GSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGP 2160
G+R PGM + RTP S QQ G
Sbjct: 149 GAR-----------------------------PGMASRV---RTPTS--QQKGSRGKSYG 174
Query: 2161 GPRIPDHQRT-SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPA------ 2213
PR + +R+ S P N ++ PP S G ++ ++ P+
Sbjct: 175 RPRTSNRERSDSQPRNLSKKSYR-------------PPGGSGIGRSSELAVTPSTAKCQT 221
Query: 2214 PVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAV-------NLADSRTPAAAA 2266
P + S + + +S S M + S PT + N A +R+ +
Sbjct: 222 PTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
Query: 2267 AMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSS 2326
+ + SPR + + S + N + AR+ LS G + + + S
Sbjct: 282 SQS-RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKS 340
Query: 2327 ---SRTPQAPASANLVGPRS-----AHATAPVNIAGSRTAAALAPASLTSARMAPALSGA 2378
SRTP+ S N S +H+ + R +++ S S +P
Sbjct: 341 QNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD 400
Query: 2379 NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS 2438
+ S R P A +R R+ DR+RSR+P A SR S SR ++P++
Sbjct: 401 HSRS-RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR-SRSPNK- 457
Query: 2439 LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA 2498
A+D RS P+ D+SR S+S P+
Sbjct: 458 ----ARDHSRSRSPNKARDRSR-----------SRS----------------------PS 480
Query: 2499 PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS 2558
HS +G P ++ R S S S S SSS
Sbjct: 481 KERDHSQLGSPSKE---------------RDHRRSRSPSKERQCRQSRSSSKERDHRRSR 525
Query: 2559 SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSS-----SSS 2613
S S P R S +P+ + R+ R P +R+ RS S S
Sbjct: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSR 585
Query: 2614 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGER 2673
SSS S S S + S S +SS + S S +P+K G + + +S + P
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
Query: 2674 RSRSP---RKPIDSLRDSRSLSYSPVERRRPSPQPS-------PRDQQSSSSERGSRRGQ 2723
RSP R P + S++ + S PS PS Q +++ + + G+
Sbjct: 646 VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGE 705
Query: 2724 RGDSRS 2729
R S S
Sbjct: 706 RSSSSS 711
Score = 83.6 bits (205), Expect = 3e-15
Identities = 155/612 (25%), Positives = 238/612 (38%), Gaps = 58/612 (9%)
Query: 2171 SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL-RTAPAANLA 2229
S P+ ++ ++LA + S+ TA P P S + + P SL T PA +
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPAS-------LKSTKSATPNRSLVPTKPATSRN 54
Query: 2230 SRI-PAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLA-DP 2287
S + P++S + + ++ R P+ N SR+ + A + T S + A D
Sbjct: 55 SVMSPSSSKSTKSTSTKRAPS-----NRPSSRSRVRSKARTPSRVSTDTRTSKASKASDV 109
Query: 2288 RTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHAT 2347
R + G RTP + S S P+ A+ P RT A G S T
Sbjct: 110 RCHQRRGTHSRG-RTPGRRGSRS---SKRSPSRASTPGRIRTHGARP-----GMASRVRT 160
Query: 2348 APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPL-SAYERVSGRTSPPLLDRAR 2406
GSR + P + R + S R P S R S P A+
Sbjct: 161 PTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTP--STAK 218
Query: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS-RCLIAQ 2465
+TP PS+ + + PSPSS ++ P++++ SP + +S +
Sbjct: 219 CQTPTGIPSKEKSDN---PSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR 275
Query: 2466 TTPVAGSQSLS-----SGAVATTTSSAG------DHNGMLSVPAPGVPHSDVGEPPASTG 2514
+ P + SQS S SG+ T S +H+ S G+ + +
Sbjct: 276 SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSH 335
Query: 2515 AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV 2574
++ S + P + R + S + S S S S SSS SSS + S
Sbjct: 336 SKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSP 395
Query: 2575 ALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS-------SSSSSS 2627
+R S + +P +A R P A+ + RS S + + S S S S S S
Sbjct: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP 455
Query: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA-LPKPASPK-----KPPPGERRSRSPRKP 2681
+ + S S S + + S S SP+K + L P+ + + P ER+ R R
Sbjct: 456 NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSS 515
Query: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR-RRETPS 2740
RS S S +RR S P+ +++ S S S + SRSPS +R RR S
Sbjct: 516 SKERDHRRSRSPSKERQRRQSRSPN-KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRS 574
Query: 2741 PRPMR-HRSSRS 2751
P R R SRS
Sbjct: 575 PSKERERRQSRS 586
Score = 77.0 bits (188), Expect = 2e-13
Identities = 171/754 (22%), Positives = 276/754 (36%), Gaps = 87/754 (11%)
Query: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP---LISRRRSRSRTSPVSRRRS 1900
+P S K S S + PA+ + ++S TP L+ + + SR S +S S
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS 62
Query: 1901 RSRTSVTRRRSRS-RASPVSRRRSRSRTPPV----TRRRSRSRTPTTR------RRSRSR 1949
+S S + +R+ S R S SR RS++RTP TR S+ R SR R
Sbjct: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGR 122
Query: 1950 TPPVTRRRSRSRTPPVTRRRSRSRTS---PITRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2006
TP RS R+P R RT P R R+ TS R +S P T R
Sbjct: 123 TPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRE 182
Query: 2007 RSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKR 2066
RS + P + +S PP RS + ++ ++P I + +S P + ++
Sbjct: 183 RSDSQPRNLSK-KSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
Query: 2067 SLTRSPPAIRRRSASGSSSDRS-------RSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119
+ I R S S ++ S +++T ++HS SR+P + + S+ SR
Sbjct: 242 VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSR 301
Query: 2120 PSMSPTPLDRCRS-----PGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDH----QRT 2170
+ R+ G+L +G R S G S PR +
Sbjct: 302 VRSHSWKRNHSRARSRTRKGILSQMG--RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNP 359
Query: 2171 SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLAS 2230
S +H+ SR S R S+ + SQ +P + + N A
Sbjct: 360 SKERSHSHSR--------SSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKAR 411
Query: 2231 RIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTP 2290
+ + +R+ + A + + SR+P A + R+ A + + R+P
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRS----RSRSPNKARDHSRSRSP 467
Query: 2291 TAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPV 2350
A + + +R+P+ S GS P+ SR+P S
Sbjct: 468 NK-ARDRSRSRSPSKERDHSQLGS---PSKERDHRRSRSPSKERQCRQSRSSSKERDHRR 523
Query: 2351 NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP 2410
+ + S+ S R + + R P E R+ DR R R+P
Sbjct: 524 SRSPSKERQRRQSRSPNKER--------DRSQSRSPSEEREHRQSRSPSKERDRRRWRSP 575
Query: 2411 PSAPS--QSRMTSE-----RAPSPSSRMGQA-PSQSLLPPAQDQPRSPVPSAFSDQSRCL 2462
QSR +SE R+ SP+ + G + P S A + R+P QSR
Sbjct: 576 SKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTS 635
Query: 2463 IAQTTPVAGSQSLSSG--AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
++ P + S T TSS + P+ T + PS
Sbjct: 636 SKESDPSQSTVPRSPDWKRSPTRTSSLSQNR-----------------TPSKTSSHSPST 678
Query: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554
+ + S + +++S ++ SSSSSS
Sbjct: 679 FPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 62.4 bits (150), Expect = 6e-09
Identities = 82/331 (24%), Positives = 129/331 (38%), Gaps = 67/331 (20%)
Query: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISD-SYVDGSSFDPQRRAREAKQPAPE 166
++ + + P H + K +R R+ + + S +R R ++ P+ E
Sbjct: 447 RDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKE 506
Query: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
R+S SS ++ + K+R RR +S SP +ER +S +S S S++
Sbjct: 507 RQ-----CRQSRSSSKERDHRRSRSPSKERQRR-QSRSPNKERDRS------QSRSPSEE 554
Query: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT 286
R+HR +S+ SK++ R+R RS S+ R S S+ D SRS
Sbjct: 555 REHR----QSRSPSKERDRRRWRS-----PSKERERRQSRSSSEERDHSRS--------- 596
Query: 287 HTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKS 346
RSP+ SG +S P R SS E A + +P ++ + + S
Sbjct: 597 -------RSPNKQSG--------YSRP------RASSKEKAHSRSRTPSKEGNHSQSRTS 635
Query: 347 ATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPP 406
+ PS ST P P P T+ LSQ PS+ S + P
Sbjct: 636 SKESDPS---QSTVPRSP----------DWKRSPTRTSSLSQN--RTPSKTSSHSPSTFP 680
Query: 407 KSPEKLPQSSSSESSPPSPQPTKVSRHASSS 437
+ L Q S + S R +SSS
Sbjct: 681 SGGQTLSQDDSQADATTSKATLPGERSSSSS 711
Score = 52.0 bits (123), Expect = 8e-06
Identities = 146/705 (20%), Positives = 235/705 (33%), Gaps = 83/705 (11%)
Query: 2079 SASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEP 2138
S+ SS S S P + + PP +L S++ + P+ S P S +
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSAT---PNRSLVPTKPATSRNSVMS 58
Query: 2139 LGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPS 2198
SS++ S + S R+ RT SR++ A
Sbjct: 59 PSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTP-------SRVSTDTRTSKASKASDVRC 111
Query: 2199 MSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLAD 2258
G +R S R+ A+ RI A + RTP
Sbjct: 112 HQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQK----G 167
Query: 2259 SRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAG--ARTPAALAALSLTGSGT 2316
SR + R+ P ++ R P + + A TP+ + TG +
Sbjct: 168 SRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPS 227
Query: 2317 PPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALS 2376
+ N PS S + + + ++ P + +P ++ + + + S R P S
Sbjct: 228 KEKSDN-PSPSSSRKVKSYGQMIIPSREKSYSPTEMS-----SRVKSYNQASTRSRPQ-S 280
Query: 2377 GANLTSPRVPLSA-----YERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRM 2431
+ SPR S + RV + RARSRT SQ S+ S S
Sbjct: 281 HSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQ---SRSHSK 337
Query: 2432 GQAPSQSLLP-----------PAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480
G++ +QS P P++++ S S+ ++ + +G S
Sbjct: 338 GKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNK 397
Query: 2481 ATTTSSAGDHNGMLSVPAPGVPHS--DVGEPPASTGAQQPSALAALQPAKERRSSSSSSS 2538
S + N P+ D + A+ S + A++R S S +
Sbjct: 398 QRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNK 457
Query: 2539 SSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEP 2598
+ S S S + + S S S S P S +P+ + R+ R
Sbjct: 458 ARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSK 517
Query: 2599 --------TPAKRKRRSSSSSSSSS---SSSSSSSSSSSSSSSSSSS------------- 2634
+P+K ++R S S + S S S S S S S
Sbjct: 518 ERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSK 577
Query: 2635 -----SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
S SSS S S SP K + P+ +S +K RSR+P K +
Sbjct: 578 ERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK---AHSRSRTPSK-----EGNH 629
Query: 2690 SLSYSPVERRRPSPQPSPR--DQQSSSSERGSRRGQRGDSRSPSH 2732
S S + + PS PR D + S + S R S++ SH
Sbjct: 630 SQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674
Score = 39.3 bits (90), Expect = 0.054
Identities = 48/184 (26%), Positives = 83/184 (45%), Gaps = 52/184 (28%)
Query: 154 QRRAREAKQPAPEPPKPYSLV----RESSSSRSPTPKQKKKKKK---KDRGRR-SESSSP 205
+R+ R+++ P E + S RE SRSP+ ++ +++ + K+R RR S SSS
Sbjct: 530 ERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSE 589
Query: 206 RRERKKSSKKKKH----RSESESKKRKH-RSPTPK-----SKRKSKDKKRKRSRSTTP-A 254
R+ +S K R + SK++ H RS TP S+ ++ K+ S+ST P +
Sbjct: 590 ERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRS 649
Query: 255 PKSRRAHRSTSA----------------------------DSASSSDTSRS-----RSRS 281
P +R+ TS+ DS + + TS++ RS S
Sbjct: 650 PDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSS 709
Query: 282 AAAK 285
+++K
Sbjct: 710 SSSK 713
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 211 bits (537), Expect = 8e-54
Identities = 250/870 (28%), Positives = 351/870 (40%), Gaps = 161/870 (18%)
Query: 1392 EKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGS 1451
EK Q D + SRE+ + SP + R+PS R R SSP R+
Sbjct: 139 EKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKS--RSPSPRRR--SSPVRRERK 194
Query: 1452 GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLT 1511
+ SR PR ++ R SP P P + ++P PE + K
Sbjct: 195 RSHSRS------------PRHRTKSR-----SPSP-----APEKKEKTPELPEPSVKVKE 232
Query: 1512 PQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRT 1571
P + + S S + + P +P P+E S +S K K +T
Sbjct: 233 PSVQEATSTSD-----ILKVP-------------KPEPIPEPKEPSPEKNSKKEKEKEKT 274
Query: 1572 PLRQRSRSGSSPEVDSK--SRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAP 1629
R RSRS S S+ S PRR S + R +PR + P+ P
Sbjct: 275 RPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP 334
Query: 1630 RALPRRSRSGSSSKGR-GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688
RRSRS + R S GSSS+ SS SRS P+ K + P R
Sbjct: 335 PPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR-----------SRSPPKKPPKRTSSPPR 383
Query: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
++ R SP + R R S A+ P+TR SP P + +R+ + R S
Sbjct: 384 KTRRLSPSASPPRRRHRPSPPATPPPKTR-------------HSPTPQQSNRTRKSRVSV 430
Query: 1749 SSPRTK--------TTSRRGRSPSPKPRGLQRSRS--------------RSRREKTRTTR 1786
S RT T R SP+PKPR ++ S S + RR+ R +
Sbjct: 431 SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ 490
Query: 1787 R--RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA-RQESSRTSSRRRRGRSR 1843
+ D SS S R +RS ++ RRR S S SP+ R+ TS R RR RS
Sbjct: 491 QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP 550
Query: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
+PP +R+ R SPAP R R +P R RTP SP RRRS S
Sbjct: 551 SPPPTRR--RRSPSPAPPPRRRRTPTPPPRR----RTP-----------SPPPRRRSPS- 592
Query: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP 1963
R + P+ RR S S P +RR+ S P +RR+ S +PP RR S S P
Sbjct: 593 -------PRRYSPPIQRRYSPS---PPPKRRTASPPPPPKRRA-SPSPPPKRRVSHSPPP 641
Query: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRR---RSRSRTSPVTRRRSRS 2020
+ R+SP+T+RRS S +S + S SR++ R R SP R S
Sbjct: 642 -------KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS 694
Query: 2021 RTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSA 2080
+PP +RR + S R++S S S IRR SRTP + K++ + SP ++RR S+
Sbjct: 695 SSPPPVRRGASSSP---QRRQSPSPSTRPIRR--VSRTPEPKKIKKAASPSPQSVRRVSS 749
Query: 2081 SGSSSDRSRSAT--PPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEP 2138
S S S A PPA PP + S S P++ P+ + +S P
Sbjct: 750 SRSVSGSPEPAAKKPPA---------PPSPVQSQSPSTNWSPAV---PVKKAKS-----P 792
Query: 2139 LGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPS 2198
S P + Q+ GG + H++ + H + + A+ A + P
Sbjct: 793 TPSPSPPRNSDQEGGGKKKKKKKDK--KHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAI 850
Query: 2199 MSAAGLAARMSQVPAPVPLMSLRTAPAANL 2228
+A A+ V AP P + NL
Sbjct: 851 AAATTTLAQEEPVAAPEPKKETESEAEDNL 880
Score = 194 bits (494), Expect = 8e-49
Identities = 211/668 (31%), Positives = 297/668 (44%), Gaps = 96/668 (14%)
Query: 436 SSPESPKPAPAPGSHREISSSPTSKNRSHG-RAKRDKSHSHTPSRRMGRSRSPATAKRGR 494
SS E + + +P R S SP+ + RS R +R +SHS +P R +SRSP+ A
Sbjct: 161 SSREKRERSRSP--RRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRT-KSRSPSPAPE-- 215
Query: 495 SRSRTPTKRGHS-RSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRN----TQ 549
+ +TP S + + P + + S + P+ + P S+ T+
Sbjct: 216 KKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTR 275
Query: 550 RRGRSRSARRGRSHSRSPAT-------RGRSRSRTPARRGRSRSRTPARRRS-------- 594
R RSRS R R+ SRSP+ R RSRS +P RR R R RRR+
Sbjct: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPP 335
Query: 595 ----RSRTPTRRR----------------SRSRTPARRGRSRSRTP---ARRRSRTRSPV 631
RSR+P RRR SRSR+P ++ R+ +P RR S + SP
Sbjct: 336 PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP 395
Query: 632 RRRSRSRSPARRSGRSR-SRTPARRGRSR-SRTPARRGRSRSRTPARRSGRSR-SRTPAR 688
RRR R PA ++R S TP + R+R SR GR+ + + R S +PA
Sbjct: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAP 455
Query: 689 RGR----SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGR-SGSSS----ERKNKS----- 734
+ R S S + G+ + V++ R + R Q+ SGSSS ER +S
Sbjct: 456 KPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNG 515
Query: 735 ----RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKS 790
R SRS S K+ + +S R R SP R RRS S + P ++++
Sbjct: 516 EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRR---RRSPSPAPPPRRRRT 572
Query: 791 QTPPRRSRSGSSQPKAKSRTPPRRS-----RSSSSPPPKQKSKTPSRQSHSSSSPHPKVK 845
TPP R R+ S P+ +S +P R S R S SPPPK+++ +P +SP P
Sbjct: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP--- 629
Query: 846 SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSP-PRVKSSTP 904
P R+ S + P S +RRS S K +PSR + SP P + S
Sbjct: 630 --PPKRRVSHSPPPKQRSSPVTKRRS--PSLSSKHRKGSSPSRSTREARSPQPNKRHSPS 685
Query: 905 PR-QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRT-TPRR-SRSVSPCSNVES 961
PR ++P SSSP P + S QR S S S P R SRT P++ ++ SP
Sbjct: 686 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR 745
Query: 962 RLLPRYSHSGSSSPDTKVKPETP-PRQSHSGSIS-----PYPKVKAQTP-PGPSLSGSKS 1014
R+ S SGS P K P P P QS S S + P K K+ TP P P + +
Sbjct: 746 RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQE 805
Query: 1015 PCPQEKSK 1022
++K K
Sbjct: 806 GGGKKKKK 813
Score = 189 bits (480), Expect = 3e-47
Identities = 233/816 (28%), Positives = 331/816 (40%), Gaps = 155/816 (18%)
Query: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664
++K + + D + + + R RSRS K R PSP SS P
Sbjct: 138 QEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSS--------PV 189
Query: 1665 SRTARRGSRSSPEPKTKSRTP-PRRRSSRSSPELTRKARLSRRS--RSASSSPETRSRTP 1721
R +R SP +TKSR+P P +PEL + + + A+S+ +
Sbjct: 190 RRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPK 249
Query: 1722 PRHRRSPSVSSPEP-AEKSRSSRRRRSASSPRTKTTSR-RGRSPS-PKPRGLQRSRSRSR 1778
P P SPE ++K + + R S R+K+ SR R RSPS +PR RSRSRS
Sbjct: 250 PEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSY 309
Query: 1779 REKTRTTRRRDRSGSSQSTSRRR----QRSRSRSRVTRRRRGG----------SGYHSRS 1824
+ R + RR S ++ RR + RSRS V RRRR S SRS
Sbjct: 310 SPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS 369
Query: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
P ++ RTSS R+ R +P S R R R SP ++R SP + +R+R +S
Sbjct: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429
Query: 1885 ----------------RRRSRSRTSPVSRRRSRSRT------------SVTRRRSRSRAS 1916
+R +P R+ S + SV +RR R +
Sbjct: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489
Query: 1917 PVSR--------------RRSRSRTPPVTRRR----SRSRTPTTRRRSRSRTPPVTRRRS 1958
S +RS + V RRR SRS +P+ R+R + +P RRRS
Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549
Query: 1959 RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS--RTSPVTRR 2016
S PP RRRS S P RRR+ +P RRR+ SP RRRS S R SP +R
Sbjct: 550 PS-PPPTRRRRSPSPAPPPRRRRT---PTPPPRRRT---PSPPPRRRSPSPRRYSPPIQR 602
Query: 2017 RSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIR 2076
R PP +RR+ S P P KR S SP RR S S P+ RS P +
Sbjct: 603 RYSPSPPP--KRRTASPPP--PPKRRASPSPPPKRRVSHSPPPKQ--------RSSPVTK 650
Query: 2077 RRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGML 2136
RRS S SS R S+ +TR +R+P +P+ +P R R+P
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTRE---ARSP-------------QPNKRHSPSPRPRAPQ-- 692
Query: 2137 EPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP 2196
+S +P V + A S P +++ P R++ + A P
Sbjct: 693 ----TSSSPPPVRRGASSS---------PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP 739
Query: 2197 PSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNL 2256
S +++ S +P P AP + + S+ P+ + + PA+P V
Sbjct: 740 SPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWS---------PAVP--VKK 788
Query: 2257 ADSRTPAAAAAMNLASPRTAVAPSAVNLADPR--------------TPTAPAVNLAGART 2302
A S TP+ + N S + D + A A A A T
Sbjct: 789 AKSPTPSPSPPRN--SDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVT 846
Query: 2303 PAALAALSLTGSGTPPTAANYPSSSRTPQAPASANL 2338
PAA+AA + T + P AA P + ++ A NL
Sbjct: 847 PAAIAAATTTLAQEEPVAA--PEPKKETESEAEDNL 880
Score = 186 bits (473), Expect = 2e-46
Identities = 222/833 (26%), Positives = 333/833 (39%), Gaps = 105/833 (12%)
Query: 75 EMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNER 134
E+ +E+ + Q QEK+A+ + ++D + KEE R + +
Sbjct: 125 ELKKEEIKQRQIEQEKLASMKKQ--DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP 182
Query: 135 LRAAFGISDSYVDGSSFDPQRRAR--------EAKQPAPEPPKPYSLVRESSSSRSPTPK 186
R + + S P+ R + E K+ PE P+P V+E S + +
Sbjct: 183 RRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTS 242
Query: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRK 246
K K + + SP + KK +K+K R S S+ + +S ++ ++R
Sbjct: 243 DILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRH 302
Query: 247 RSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG 306
RSRS + +P+ R + R + R R+ + RS SP RR
Sbjct: 303 RSRSRSYSPRRRPSPRRRPS----------PRRRTPPRRMPPPPRHRRSRSPVRRRRRSS 352
Query: 307 DAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366
+ ++S+ R SP P P + ++ PS SP R P PPA
Sbjct: 353 ASLSGSSSSSSSSRSRSP------PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPA- 405
Query: 367 TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQ 426
TP RH +PQ T S+ V+P + + K EK ES P+P+
Sbjct: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKV---TKHKGTEK------RESPSPAPK 456
Query: 427 PTKVSRHASSSPESPKPAPAPG-------SHREISSSPTSKNRSHGRAKRDKSHSHTPSR 479
P KV S + K A A + SS S + S +R K SH +
Sbjct: 457 PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK-RSHVKNG 515
Query: 480 RMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQR 539
+GR R + SRS +P+ R + SP+ RR RS S P RR RS SP
Sbjct: 516 EVGRRR-----RHSPSRSASPSPRKRQKETSPRGRRRRSP-----SPPPTRRRRSPSPAP 565
Query: 540 PGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTP 599
P RR R+ + P R RTP+ R RS +P R S
Sbjct: 566 P----------------PRRRRTPTPPP------RRRTPSPPPRRRSPSP---RRYSPPI 600
Query: 600 TRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSR 659
RR S S P RR S P RR S + P RR S S P +RS +P + RS
Sbjct: 601 QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRS------SPVTKRRSP 654
Query: 660 SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQ 719
S + R + +P+R + +RS P +R R S S VRRG S S PQ
Sbjct: 655 SLSSKHR---KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS--PQ 709
Query: 720 RRGRSGSSSER--KNKSRTSQ-RRSRSNSSPEMKK-SRISSRRSRSLSSPRSKAKSRLSL 775
RR +S S S R + SRT + ++ + +SP + R+SS RS S SP AK +
Sbjct: 710 RR-QSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS-GSPEPAAKKPPAP 767
Query: 776 RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR--- 832
+ SP P ++++S + P +PPR S K+K K
Sbjct: 768 PSPVQSQSPSTNWSPAVPVKKAKSPTPSP-----SPPRNSDQEGGGKKKKKKKDKKHKKD 822
Query: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRT 885
+ H H K K+ ++T P A + T + ++P+P+ ++ +
Sbjct: 823 KKHKKHKKHKKEKAVAAAAAAAVT-PAAIAAATTTLAQEEPVAAPEPKKETES 874
Score = 181 bits (460), Expect = 7e-45
Identities = 215/804 (26%), Positives = 330/804 (41%), Gaps = 96/804 (11%)
Query: 170 PYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESES----- 224
P L + + + P+ + KK++ + + + +++ K K+ + E ES
Sbjct: 107 PLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKR 166
Query: 225 ------KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
++RK RSP+P +R+S +R+R RS + +P+ R RS S T
Sbjct: 167 ERSRSPRRRKSRSPSP--RRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
Query: 279 SRSAAAK-------THTTAL----------AGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321
S K T T+ + + PSP + E + + P + S +
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSK- 283
Query: 322 SSPETATKQPSSPYEDKDKDKKEKSAT---RPSPSPERSSTGPEPPAPTPLLAERHGGSP 378
S T ++ PS + + +S + RPSP S PP P RH S
Sbjct: 284 SRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMP-PPPRHRRSR 342
Query: 379 QPLATTPLSQEPVN-PPSEASPTRDRSPPKSPEK---LPQSSSSESSPPSPQPTKVSRHA 434
P+ S ++ S +S +R RSPPK P K P + SP + P + RH
Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR--RHR 400
Query: 435 SSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR 494
S P +P P + SPT + + R R S +P R G+ ++
Sbjct: 401 PSPPATPPP--------KTRHSPTPQQSNRTRKSR---VSVSPGRTSGKVTKHKGTEKRE 449
Query: 495 SRSRTPTKRGHSRSRSPQWRRSRSAQRWG-RSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553
S S P R S S + + + A + R RR +S G S S +R R
Sbjct: 450 SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR 509
Query: 554 S--RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPAR 611
S ++ GR SP+ RS S +P +R + S RRRS S PTRRR RS +PA
Sbjct: 510 SHVKNGEVGRRRRHSPS---RSASPSPRKRQKETSPRGRRRRSPSPPPTRRR-RSPSPA- 564
Query: 612 RGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT-PARRGRSRSRTPARRGRSR 670
P RRR P RRR+ S P RRS R + P +R S S P RR S
Sbjct: 565 -------PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP 617
Query: 671 SRTPARRSG------RSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
P RR+ R S +P + RS T RR S S S R+G S SR+ R RS
Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLS-SKHRKGSSPSRS-TREARS 675
Query: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSL----RRSLS 780
++R + S + S+S P +++ SS + R SP ++ R+S ++
Sbjct: 676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKK 735
Query: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
+SP P+ + RS SGS +P AK PP +PP +S++PS + S + P
Sbjct: 736 AASPSPQSVRRVSSSRSVSGSPEPAAKK--PP-------APPSPVQSQSPS-TNWSPAVP 785
Query: 841 HPKVKSGTPPRQGSITSPQ------ANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894
K KS TP S Q ++ ++ K + + + +
Sbjct: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAV 845
Query: 895 SPPRVKSSTPPRQSPSRSSSPQPK 918
+P + ++T ++P+PK
Sbjct: 846 TPAAIAAATTTLAQEEPVAAPEPK 869
Score = 140 bits (354), Expect = 1e-32
Identities = 182/683 (26%), Positives = 275/683 (40%), Gaps = 97/683 (14%)
Query: 1737 EKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQS 1796
EK S +R + SPR R+ RSPSP+ R R R +R +R+ R R +S S
Sbjct: 158 EKESSREKRERSRSPRR----RKSRSPSPRRRSSPVRRER-KRSHSRSPRHRTKSRSPSP 212
Query: 1797 TSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT 1856
+++++ + + + P+ QE++ TS + + P ++ S +
Sbjct: 213 APEKKEKTPELPEPSVK--------VKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKN 264
Query: 1857 SPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRAS 1916
S ++ ++R + +SRSRT R RS S T P R RSRSR+ RRR R
Sbjct: 265 SKKEKEKEKTRPRSRSRSKSRSRT----RSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR 320
Query: 1917 PVSRRRS--RSRTPPVTRRRSRSRTPTTRRR---------------SRSRTPPVTRRRSR 1959
P RRR+ R PP RRSRS P RRR SRSR+PP +
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRS--PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT 378
Query: 1960 SRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2019
S P TRR S S + P R R R SP ++R SP ++ +R+R S V+ R
Sbjct: 379 SSPPRKTRRLSPSASPP----RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434
Query: 2020 -----SRTPPAIRRRSRSRTPLLPRKRSRSRS------------PLAIRRRSRSRTPRTA 2062
++ +R S S P PRK S S + RR+ R + +++
Sbjct: 435 TSGKVTKHKGTEKRESPSPAP-KPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSS 493
Query: 2063 ------------RGKRSLTRSPPAIRR------RSASGSSSDRSRSATPPATRNHSGSRT 2104
R KRS ++ RR RSAS S R + +P R S S
Sbjct: 494 SDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPP 553
Query: 2105 PPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRI 2164
P S + R +PTP R R+P P R+P P P
Sbjct: 554 PTRRRRSPSPAPPPRRRRTPTPPPRRRTP---SPPPRRRSPSPRRYSPPIQRRYSPSP-- 608
Query: 2165 PDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAP 2224
P +RT+ P + R + + + PPP ++ + R S P +S +
Sbjct: 609 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRS------PSLSSKHRK 662
Query: 2225 AANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNL 2284
++ + A + N + +P P A + S P A + R + +PS +
Sbjct: 663 GSSPSRSTREARSPQPNKRHSPSPR-PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPI 721
Query: 2285 AD-PRTPTAPAVNLAGARTPAALAALSLTG--SGTPPTAANYPSSSRTPQAPASANLVGP 2341
RTP + A + +P ++ +S + SG+P AA P P P+ P
Sbjct: 722 RRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP-----PAPPSPVQSQSP 776
Query: 2342 RSAHATA-PVNIAGSRTAAALAP 2363
+ + A PV A S T + P
Sbjct: 777 STNWSPAVPVKKAKSPTPSPSPP 799
Score = 139 bits (349), Expect = 5e-32
Identities = 209/827 (25%), Positives = 311/827 (37%), Gaps = 137/827 (16%)
Query: 1862 KRSRSRASPATHRRSRSRTPLISRRRSRS-----RTSPV--SRRRSRSRTSVTRRRSRSR 1914
KR + + +R RSR+P RR+SRS R+SPV R+RS SR+ R R++SR
Sbjct: 153 KRDKEEKESSREKRERSRSP--RRRKSRSPSPRRRSSPVRRERKRSHSRS--PRHRTKSR 208
Query: 1915 ASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS-------RTPPVTRRRSRSRTPPVTR 1967
SP + +TP + + + P+ + + + + P+ + S +
Sbjct: 209 -SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKK 267
Query: 1968 RRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIR 2027
+ + +T P +R RS+SR+ TR RS S T P R RSRSR+ RR S R P R
Sbjct: 268 EKEKEKTRPRSRSRSKSRSR--TRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR 325
Query: 2028 RRSRSRTPLLPRKRSRSRSPLAIRRR-SRSRTPRTARGKRSLTRSPP-AIRRRSASGSSS 2085
R R P PR R RSRSP+ RRR S S + ++ S +RSPP +R++S
Sbjct: 326 RTPPRRMPPPPRHR-RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK 384
Query: 2086 DR--SRSATPPATRNH-SGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSS 2142
R S SA+PP R+ S TPP + SPTP R+ +
Sbjct: 385 TRRLSPSASPPRRRHRPSPPATPP-----------PKTRHSPTPQQSNRTRKSRVSVSPG 433
Query: 2143 RTPMSVLQQAGGSMMDGPGPR-IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA 2201
RT V + G + P P P S E ++A A + R S+
Sbjct: 434 RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSS 493
Query: 2202 AGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRT 2261
+ + S ++ P+ SA+ S R T+ R+
Sbjct: 494 SDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS----PSPRKRQKETSPRGRRRRS 549
Query: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA 2321
P+ SP A P RTPT P RTP +PP
Sbjct: 550 PSPPPTRRRRSPSPAPPPRR-----RRTPTPP----PRRRTP------------SPPPRR 588
Query: 2322 NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLT 2381
PS R P +P RTA+ P
Sbjct: 589 RSPSPRR----------YSPPIQRRYSPSPPPKRRTASPPPPP----------------- 621
Query: 2382 SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSS--RMGQAPSQSL 2439
+R + + PP R S +PP S +T R+PS SS R G +PS+S
Sbjct: 622 ---------KRRASPSPPP--KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRS- 669
Query: 2440 LPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAP 2499
+ RSP P+ S P A S S V SS+ P+P
Sbjct: 670 ----TREARSPQPNKRHSPS------PRPRAPQTSSSPPPVRRGASSSPQRR---QSPSP 716
Query: 2500 GVPH----SDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
S EP A PS P RR SSS S S S ++ + S
Sbjct: 717 STRPIRRVSRTPEPKKIKKAASPS------PQSVRRVSSSRSVSGSPEPAAKKPPAPPSP 770
Query: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
S S + S P V +K+ SPTP+P R + +K++
Sbjct: 771 VQSQSPSTNWS-----PAVPVKKAKSPTPSPSPP----RNSDQEGGGKKKKKKKDKKHKK 821
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
+ +++++++ + ++ ++++ + A+ P A P+P
Sbjct: 822 DKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868
Score = 123 bits (309), Expect = 2e-27
Identities = 172/677 (25%), Positives = 265/677 (39%), Gaps = 129/677 (19%)
Query: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLS-SPRSKAKSRLSLRRSLSGSSP 784
SS E++ +SR+ +RR + SP + S + R RS S SPR + KSR SP
Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSR--------SPSP 212
Query: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS-------PPPKQKSKTPSRQSHSS 837
P++K +TP +P K + P + +S+S P P + K PS + +S
Sbjct: 213 APEKKEKTPEL------PEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSK 266
Query: 838 -----------SSPHPKVKSGTPPRQGSITSPQ----ANEQSVTPQRRSCFESSPDP--- 879
S K +S T R S T P+ + +S +P+RR P P
Sbjct: 267 KEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
Query: 880 -----------ELKSRTPSRH--------SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVK 920
+SR+P R S S SS +S +PP++ P R+SSP K +
Sbjct: 327 TPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR 386
Query: 921 AI---ISPRQRSHSGSSSPSPSRVTSRT-TPRRSR-------SVSPCSNVESRLLPRYSH 969
+ SP +R H S +P T + TP++S SVSP ++
Sbjct: 387 RLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP-GRTSGKVTKHKGT 445
Query: 970 SGSSSPDTKVKP----------ETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE 1019
SP KP + + + + S+ + + Q S SGS S E
Sbjct: 446 EKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505
Query: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP--DHRSDTSSPEVR 1077
+ K S V++ G + P S S K Q +TSP R S P R
Sbjct: 506 RPKRSHVKNGE------VGRRRRHSPSRS---ASPSPRKRQKETSPRGRRRRSPSPPPTR 556
Query: 1078 QSHSESPSLQSKSQTSP-KGGRSRSSSPVTELASRSPIRQD--------------RGEFS 1122
+ S SP+ + + +P R R+ SP S SP R R S
Sbjct: 557 RRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTAS 616
Query: 1123 ASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESK-EKMALPPQEDATASPP 1181
P K SP + S S P +S + + R + SK K + P + A P
Sbjct: 617 PPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP 676
Query: 1182 RQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEV 1241
+ + SP P P++S +PP R GA SSP+ ++ S P++ +
Sbjct: 677 QPNKRHSPSPRPRAPQTS-------SSPPPVRRGASSSPQRRQSPS--PSTRPIRRVSRT 727
Query: 1242 -----VEKSEEPAGQILSHLSSELKEMSTSNFESSPE-VEERPAVSLTLDQSQSQASLEA 1295
++K+ P+ Q + +S S+ + SPE ++P + QSQS ++ +
Sbjct: 728 PEPKKIKKAASPSPQSVRRVS------SSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWS 781
Query: 1296 VEVPSMASSWGGPHFSP 1312
VP + P SP
Sbjct: 782 PAVPVKKAKSPTPSPSP 798
Score = 112 bits (281), Expect = 4e-24
Identities = 164/627 (26%), Positives = 235/627 (37%), Gaps = 112/627 (17%)
Query: 715 SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774
S Q + E K SR + RSRS P +KSR S R RS R + +S
Sbjct: 143 SMKKQDEDKDKRDKEEKESSREKRERSRS---PRRRKSRSPSPRRRSSPVRRERKRSH-- 197
Query: 775 LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
S++P R++S S P P ++ ++ P P K K PS Q
Sbjct: 198 ---------------SRSPRHRTKSRSPSP-----APEKKEKTPELPEPSVKVKEPSVQE 237
Query: 835 HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894
+S+S KV P + SP+ N + + ++ S + +SRT SR S S +
Sbjct: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR-SPSHT 296
Query: 895 SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSR--- 951
P R S SP R SP+ + SPR+R+ P P SR+ RR R
Sbjct: 297 RPRRRHRSRSRSYSPRRRPSPRRRP----SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS 352
Query: 952 -----SVSPCSNVESRLLPRYSHSGSSSPDTKVK----PETPPRQSHSGSISPYPKVKAQ 1002
S S S+ SR P+ +SSP K + +PPR+ H S P K +
Sbjct: 353 ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412
Query: 1003 TPPGP-----------SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGV---KSSTPPGES 1048
P P S+S ++ K K + + P V +S G
Sbjct: 413 HSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472
Query: 1049 YFGVSSLQLKGQ-----SQTSPDHRSDTSSPEVR------------------QSHSESPS 1085
S+Q + Q Q+S D S +SS + R S S SPS
Sbjct: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS 532
Query: 1086 LQSK-SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSS 1144
+ + +TSP+G R RS SP RSP S +P + +P + S
Sbjct: 533 PRKRQKETSPRGRRRRSPSPPPTRRRRSP--------SPAPPPRRRRTPTPPPRRRTPSP 584
Query: 1145 YPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS-PPRQKDKFSPFPVQDRPESSLVFK 1203
P S S R + PP + TAS PP K + SP P R S
Sbjct: 585 PPRRRSPS---PRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSH---- 637
Query: 1204 DTLRTPPRERSGAGSSPETKEQNSAL---------PTSSQDEELMEVVEKSEEPAGQILS 1254
PP++R SSP TK ++ +L P+ S E K P+ + +
Sbjct: 638 ---SPPPKQR----SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Query: 1255 HLSSELKEMSTSNFESSPEVEERPAVS 1281
+S SSP+ + P+ S
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPS 717
Score = 110 bits (276), Expect = 1e-23
Identities = 191/842 (22%), Positives = 300/842 (35%), Gaps = 117/842 (13%)
Query: 894 SSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV 953
SS + + S PR+ SRS SP+ + + R+RSHS R T RS S
Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS--------RSPRHRTKSRSPSP 212
Query: 954 SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK 1013
+P ++ LP P KVK + + + I PK + P K
Sbjct: 213 APEKKEKTPELPE--------PSVKVKEPSVQEATSTSDILKVPKPEPIPEP-------K 257
Query: 1014 SPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQT---SPDH--- 1067
P P++ SK K T P S + K +S+T SP H
Sbjct: 258 EPSPEKNSKKEKE-------------KEKTRPR------SRSRSKSRSRTRSRSPSHTRP 298
Query: 1068 ------RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEF 1121
RS + SP R S PS + +T P+ R P SRSP+R+ R
Sbjct: 299 RRRHRSRSRSYSPRRRPSPRRRPS--PRRRTPPR----RMPPPPRHRRSRSPVRRRRR-- 350
Query: 1122 SASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPP 1181
S++ + S S SR +S P S+ RL + S + P AT P
Sbjct: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPP- 409
Query: 1182 RQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEV 1241
K + SP P Q S+ K + P SG + + E+ + P+ + +E+
Sbjct: 410 --KTRHSPTPQQ----SNRTRKSRVSVSPGRTSGKVTKHKGTEKRES-PSPAPKPRKVEL 462
Query: 1242 VEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSM 1301
E E+ G++ + + V++R QS S +
Sbjct: 463 SESEEDKGGKMAA----------------ADSVQQRRQYRRQNQQSSSDSG--------- 497
Query: 1302 ASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLN 1361
SS P+ + N + SP + P + T + + P
Sbjct: 498 -SSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTR 556
Query: 1362 QLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAV-PRTPSRERSS 1420
+ + PS + R+ +P + S + S P+ P P + R++
Sbjct: 557 RRRS-PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615
Query: 1421 SASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSEC 1480
S P + P P +R S S P + S R S S SS K +PSR E
Sbjct: 616 SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKG--SSPSRSTREA 673
Query: 1481 DSSPEPKALPQTPRPRSRSPSS---PELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537
S K +PRPR+ SS P +PQR +S S S+ + V+RTP ++
Sbjct: 674 RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI 733
Query: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGS---SPEVDSKSRLSPR 1594
+ +S S P +K P +S+S S SP V K SP
Sbjct: 734 KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSP- 792
Query: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
+ S S P D+ + G + K + + + K + + +++
Sbjct: 793 -TPSPSPPRNSDQ-------EGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAA 844
Query: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
+ + A+ ++PEPK ++ + L KA R R A SP
Sbjct: 845 VTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKA--LRSMRKAQVSP 902
Query: 1715 ET 1716
++
Sbjct: 903 QS 904
Score = 110 bits (274), Expect = 2e-23
Identities = 195/846 (23%), Positives = 294/846 (34%), Gaps = 185/846 (21%)
Query: 1909 RRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTR--RRSRSRTPPVT 1966
+R + +R RSR+P RR +SR+P+ RRRS PV R +RS SR+P
Sbjct: 153 KRDKEEKESSREKRERSRSP----RRRKSRSPSPRRRSS----PVRRERKRSHSRSP--- 201
Query: 1967 RRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRS----RSRT 2022
R R++SR SP + +T + + + V S S V + + +
Sbjct: 202 RHRTKSR-SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS 260
Query: 2023 PPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASG 2082
P ++ + + PR RSRS+S R R+RSR+P R +R R RS S
Sbjct: 261 PEKNSKKEKEKEKTRPRSRSRSKS----RSRTRSRSPSHTRPRR---------RHRSRSR 307
Query: 2083 SSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSS 2142
S S R R + P R RTPP RM R S +P+ R R S
Sbjct: 308 SYSPRRRPS--PRRRPSPRRRTPP-----RRMPPPPRHRRSRSPVRRRRR---------S 351
Query: 2143 RTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAA 2202
+S + S P+ P + +S P T R PS S
Sbjct: 352 SASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK----------------TRRLSPSASPP 395
Query: 2203 GLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTP 2262
R S P P R +P ++R + ++++ RT T + R
Sbjct: 396 RRRHRPSPPATPPP--KTRHSPTPQQSNR---TRKSRVSVSPGRTSGKVTKHKGTEKRE- 449
Query: 2263 AAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAAN 2322
SP A P V L++ + A + S + +++
Sbjct: 450 ---------SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
Query: 2323 YPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTS 2382
R ++ VG R H+ SR+A+ S
Sbjct: 501 SSEDERPKRSHVKNGEVGRRRRHSP-------SRSASP---------------------S 532
Query: 2383 PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP 2442
PR + TSP R R R PS P R S +P+P R + P+ PP
Sbjct: 533 PR-------KRQKETSP----RGRRRRSPSPPPTRRRRSP-SPAPPPRRRRTPT----PP 576
Query: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
+ + SP P S R + P+ S S T S P P
Sbjct: 577 PRRRTPSPPPRRRSPSPR---RYSPPIQRRYSPSPPPKRRTASP----------PPPPKR 623
Query: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS-------- 2554
+ PP + P P +RRS S SS SS S S+ + S
Sbjct: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHS 683
Query: 2555 -SSGSSSSDSEGSSLPVQPEVAL--KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611
S + + S PV+ + +R SP+P+ + R R PEP K+
Sbjct: 684 PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKK-------- 735
Query: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671
++S S S SSS S S S ++ PA P P P++ P
Sbjct: 736 ----------AASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
Query: 2672 ERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
++++SP PSP P Q ++ ++ + +
Sbjct: 786 VKKAKSP---------------------TPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824
Query: 2732 HKRRRE 2737
HK+ ++
Sbjct: 825 HKKHKK 830
Score = 102 bits (253), Expect = 7e-21
Identities = 116/393 (29%), Positives = 153/393 (38%), Gaps = 61/393 (15%)
Query: 2405 ARSRTPPSAP-----SQSRMTSERAPSPSS-RMGQAPSQSLLPPAQDQPRSPVPSAFSDQ 2458
+RSR+PP P S R T +PS S R PS PP + + SP P S++
Sbjct: 365 SRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR-HSPTPQQ-SNR 422
Query: 2459 SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQP 2518
+R + V+ S +SG V T G PAP ++ E G +
Sbjct: 423 TR-----KSRVSVSPGRTSGKV---TKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474
Query: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS--------------SGSSSSDSE 2564
+A + Q + RR + SSS S SSSSS S S S+S
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
Query: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
P +R PSP P R R P P P R+RR+ + + S
Sbjct: 535 KRQKETSPRGRRRRSPSPPPT-----RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRR 589
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK------PPPGERRS--- 2675
S S S S S + P P+ P+ P K PPP +R S
Sbjct: 590 SPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVT 649
Query: 2676 --RSP------RKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG----- 2722
RSP RK R +R + SP +R SP P PR Q+SSS RRG
Sbjct: 650 KRRSPSLSSKHRKGSSPSRSTRE-ARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSP 708
Query: 2723 QRGDSRSPSHK---RRRETPSPRPMRHRSSRSP 2752
QR S SPS + R TP P+ ++ +S SP
Sbjct: 709 QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 741
Score = 100 bits (250), Expect = 2e-20
Identities = 114/387 (29%), Positives = 158/387 (40%), Gaps = 44/387 (11%)
Query: 2388 SAYERVSGRTSPPLLDRA--RSRTPPSAPSQSRMTSE---RAPSPSSRMGQAPSQSLLPP 2442
S E+ +T P R+ RSRT +PS +R R+ S S R +P + P
Sbjct: 265 SKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPR 324
Query: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
+ PR P +SR + + + S S SS + +++ S + P P
Sbjct: 325 RRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS----------PPKKP 374
Query: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
PP T PSA P + R S ++ + S + S+ + S S
Sbjct: 375 PKRTSSPPRKTRRLSPSA----SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV 430
Query: 2563 SEG-SSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKR-------------KRRSS 2608
S G +S V ++ SP+PAPK E E + +R++
Sbjct: 431 SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ 490
Query: 2609 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP---KPASP 2665
SSS S SSSSS S + S S S+SPSP K + P + SP
Sbjct: 491 QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP 550
Query: 2666 KKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725
PP RRS SP P R + +P RRR +P P PR ++S S R S QR
Sbjct: 551 SPPPTRRRRSPSPAPP-----PRRRRTPTPPPRRR-TPSPPPR-RRSPSPRRYSPPIQRR 603
Query: 2726 DSRSPSHKRRRETPSPRPMRHRSSRSP 2752
S SP KRR +P P P R R+S SP
Sbjct: 604 YSPSPPPKRRTASPPPPPKR-RASPSP 629
Score = 91.7 bits (226), Expect = 9e-18
Identities = 114/441 (25%), Positives = 158/441 (35%), Gaps = 116/441 (26%)
Query: 2403 DRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP---------------SQSLLPPAQDQP 2447
D + + SR ER+ SP R ++P S S P + +
Sbjct: 148 DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKS 207
Query: 2448 RSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVG 2507
RSP P+ + + + + S+ AT+TS +L VP P P +
Sbjct: 208 RSPSPAPEKKEKTPELPEPSVKVKEPSVQE---ATSTSD------ILKVPKP-EPIPEPK 257
Query: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
EP +++ +P RS S S + S S S + S S S S
Sbjct: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP------ 311
Query: 2568 LPVQPEVALKRVPSP--TPAPKEAVREGRPPEP-------TPAKRKRRSSSSSSSSSSSS 2618
+R PSP P+P+ R P P +P +R+RRSS+S S SSSSS
Sbjct: 312 ---------RRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSS 362
Query: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA---KPGPQALPKPASPKKPPPGE-RR 2674
SSS S S +SS + S S+ P +P P A P P + P P + R
Sbjct: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNR 422
Query: 2675 SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP--------------------------- 2707
+R R + R S ++ +R SP P+P
Sbjct: 423 TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQR 482
Query: 2708 ----RDQQSSSSERGS--------------------RRGQRGDSRSPS------------ 2731
R Q SSS+ GS RR + SRS S
Sbjct: 483 RQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSP 542
Query: 2732 HKRRRETPSPRPMRHRSSRSP 2752
RRR +PSP P R R S SP
Sbjct: 543 RGRRRRSPSPPPTRRRRSPSP 563
Score = 82.0 bits (201), Expect = 7e-15
Identities = 156/713 (21%), Positives = 239/713 (33%), Gaps = 94/713 (13%)
Query: 2040 KRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
KR + + +R RSR+PR R +RSP RR S RS S +P R+
Sbjct: 153 KRDKEEKESSREKRERSRSPR-----RRKSRSPSPRRRSSPVRRERKRSHSRSP---RHR 204
Query: 2100 SGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDG 2159
+ SR+P SP P + ++P + EP + P + ++
Sbjct: 205 TKSRSP-----------------SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKV 247
Query: 2160 PGPR-IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV-PL 2217
P P IP+ + S +N + + RP + + S+ P+ P
Sbjct: 248 PKPEPIPEPKEPSPEKNSKKEK--------EKEKTRPRSRSRSKSRSRTRSRSPSHTRPR 299
Query: 2218 MSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAV 2277
R+ + R P+ +P SR+P + AS +
Sbjct: 300 RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSAS----L 355
Query: 2278 APSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASAN 2337
+ S+ + + R+ + P +P L+ S +PP + PS TP
Sbjct: 356 SGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR-RLSPSASPPRRRHRPSPPATPP------ 408
Query: 2338 LVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRT 2397
P++ H+ P +R + TS ++ SP P +V
Sbjct: 409 ---PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS-PAPKPRKVELSE 464
Query: 2398 SPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSD 2457
S D+ + Q R + SS G + S P + ++
Sbjct: 465 SEE--DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR 522
Query: 2458 QSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQ 2517
S A +P + TS G S P S PP
Sbjct: 523 HSPSRSASPSPRKRQKE---------TSPRGRRRRSPSPPPTRRRRSPSPAPP------- 566
Query: 2518 PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK 2577
P P RR+ S S S S S S +S P P K
Sbjct: 567 PRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPP----K 622
Query: 2578 RVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637
R SP+P PK V PP ++ SS + S S SS SS S S+ +
Sbjct: 623 RRASPSPPPKRRVSHSPPP--------KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR 674
Query: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE 2697
S + S SP P P + P PP S SP++ R S S S P+
Sbjct: 675 SPQPNKRHSPSPRPRAPQTSSSP-------PPVRRGASSSPQR-----RQSPSPSTRPIR 722
Query: 2698 RRRPSPQPSPRDQQSSSSERGSRR--GQRGDSRSPSHKRRRETPSPRPMRHRS 2748
R +P+P + +S S + RR R S SP ++ P P++ +S
Sbjct: 723 RVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQS 775
Score = 42.0 bits (97), Expect = 0.008
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 2661 KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSR 2720
K AS KK E + + ++ +S R+ R S SP RRR S PSPR + SS R R
Sbjct: 140 KLASMKKQD--EDKDKRDKEEKESSREKRERSRSP--RRRKSRSPSPR--RRSSPVRRER 193
Query: 2721 RGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
+ R SRSP H R ++ SP P + ++P
Sbjct: 194 K--RSHSRSPRH--RTKSRSPSPAPEKKEKTP 221
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 189 bits (479), Expect = 4e-47
Identities = 462/2067 (22%), Positives = 715/2067 (34%), Gaps = 254/2067 (12%)
Query: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHR 230
Y R+ + S +K K + E + R+R S +++ +R ++ + + R
Sbjct: 86 YESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPR 145
Query: 231 SPTPKSKRKSKDKKRKRSRSTTPAPK--SRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288
K S +KK ++ S T + + H S+ + + +T +R ++
Sbjct: 146 ETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLE 205
Query: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348
G + + G +T E S E+K ++ S
Sbjct: 206 EKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDG 265
Query: 349 RPSPSPERS---STGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPT----- 400
+ S RS +T P + R Q + S++ AS
Sbjct: 266 KSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSA 325
Query: 401 --RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT 458
+ R + P + +S +RHA +S SH + SSP
Sbjct: 326 WEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSR----GQTASSHEQARSSPG 381
Query: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ------ 512
++ S + D S R S RG S S+ GHS + Q
Sbjct: 382 ERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHG 441
Query: 513 --WRRSRSAQRWGRSRSPQRRGRSRSP-------QRPGWSRSR-NTQRRGRSRS----AR 558
R +S Q R RS +R GRS S ++P + R T GR S AR
Sbjct: 442 KAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQAR 501
Query: 559 RGRSHSRS----PATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR 614
HS S RG S R+G ++ R + S+ R+ A G+
Sbjct: 502 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQ 561
Query: 615 SRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTP 674
S SR+ +R+ R +S R SG SR + + S + +G+S
Sbjct: 562 SGSRSASRQ-------TRNEEQSGDGTRHSG-SRHHEASSQADSSRHSQVGQGQSSGPRT 613
Query: 675 ARRSGRSRSRTPARRGRSRSRTPRRG----------RSRSRSLVRRGRSHSRTPQRRGRS 724
+R G S S+ +G S G + +SR R RSH G S
Sbjct: 614 SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHS 673
Query: 725 GSSSERKNKSRTSQRRS--RSNSSPEMKKSRISSRR-----------SRSLSSPRSKAKS 771
SS RK+ +R +Q S ++ SS E +S R SR + +A S
Sbjct: 674 ADSS-RKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASS 732
Query: 772 --RLSLRRSLSGSSPCPKQ-KSQTPPRRSRSG---------SSQPKAKSRTPPRRSRSSS 819
R S R SGS + S+ +S SG S Q A+ R+ RSR S
Sbjct: 733 AVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRS-GERSRRSG 791
Query: 820 SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP 879
S + + S SH + P V+ G+ Q S S + + P
Sbjct: 792 SFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNS----RHSASQDGQDTIRGHPGS 847
Query: 880 ELKSRTPSRHSCS-----GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS- 933
+ R S H S S +++ R SR S ++S GS
Sbjct: 848 SRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSR 907
Query: 934 -SSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992
S +S R + SR R S S D++ E R S S S
Sbjct: 908 HSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSAS 967
Query: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052
+ + Q S GS+ P + + S S +S TP E+ G
Sbjct: 968 RNHRGSAQEQ-----SRHGSRHPRSHHEDRAGHGHSADSSR------QSGTPHAETSSGG 1016
Query: 1053 SSLQLKGQSQTSPDHRSDTSSPEVRQS--HSESPSLQSKSQTSPKGGRSRSSSPVTELAS 1110
+ Q+++SP R + + S HS P Q+ S G S S ++
Sbjct: 1017 QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEG 1076
Query: 1111 RSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMAL 1170
S ++ S S + G P Q Q + + S S + + E+
Sbjct: 1077 HS---EESDTQSVSGHGQDG--PHQQSHQESARDWS--GGRSGRSGSFIYQVSTHEQSES 1129
Query: 1171 PPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALP 1230
T++ RQ R +S +DT+R P R G G EQ+
Sbjct: 1130 AHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRG-GRQGSHHEQS---- 1184
Query: 1231 TSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQ 1290
V++S +G SH +S+ + S+ +S R D+
Sbjct: 1185 -----------VDRSGH-SGSHHSHTTSQGRS-DASHGQSGSRSASR---QTRKDKQSGD 1228
Query: 1291 ASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSE 1350
S + A+SW S H ++ +E S GS R S G+ ++ SE
Sbjct: 1229 GSRHSGSRHHEAASWAD---SSRHSQVG----QEQSSGS----RTSRHQGSSVSQDSDSE 1277
Query: 1351 VKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAV 1410
D + + +EQS S H P ++ S S S
Sbjct: 1278 RHSDDSERLSGSASRNHHGSSREQSRDGSRH------PGFHQEDRASHGHSADSSRQSGT 1331
Query: 1411 PRTPSRERSSSASSPEMKDGLP--RTPSRRSRSGSSP-----GLRDGSGTPSRHSLSGSS 1463
T S + SS E P R SR +S S G R S GSS
Sbjct: 1332 HHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSS 1391
Query: 1464 PGMKDIPRTPSRGRSECDSSPEPKALPQT-PRPRSRSPSSPELNNKCLTPQRERSGSESS 1522
T S G SE + A Q P +S S+ R +SG S
Sbjct: 1392 GSQV----TNSEGHSEDSDTQSVSAHGQAGPHQQSHKESA-----------RGQSGESSG 1436
Query: 1523 VDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSS 1582
+ + + ++S S Q PS ++ S + + R SR +S
Sbjct: 1437 RSRSFLYQVSSHEQSESTHGQ---TAPSTGGRQGSRHEQA-----------RNSSRHSAS 1482
Query: 1583 PEVDSKSRLSPRRSRSG--SSPEVKDKPRAAPRAQSGSDSSPEPKAPA------PRALPR 1634
+ R P SR G S + R+ S ++P+ ++ A PR+ R
Sbjct: 1483 QDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASR 1542
Query: 1635 RSR----SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS 1690
++R SG S+ G S+ S H + GS++S + S R S
Sbjct: 1543 QTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTS--RRQGSSVSQDRDS 1600
Query: 1691 SRSSPELTRKARLSRRSRSASSSPETR--SRTPPRHRRSPSVSSPEPAEKSRSS--RRRR 1746
S + R++ + R+ S+ ++R SR P H+ S AE SR S R
Sbjct: 1601 EGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQED-RASHGHSAESSRQSGTRHAE 1659
Query: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD---------RSGSSQST 1797
++S + ++ + RS + G + +S + T RR+D R S
Sbjct: 1660 TSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQA 1719
Query: 1798 SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRT---PPTSRKRSRS 1854
S S + G +G H +S QES+R S R GRS + ++ ++S S
Sbjct: 1720 SDSEGHSEESDTQSVSAHGQAGPHQQS--HQESTRGQSGERSGRSGSFLYQVSTHEQSES 1777
Query: 1855 ---RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRS 1911
RT P+ R RSR H ++R S R S S+ + R + R+ S
Sbjct: 1778 AHGRTGPSTGGRQRSR-----HEQARD-----SSRHSASQEGQDTIRGHPGSSRGGRQGS 1827
Query: 1912 RSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSR 1971
S S S S T S+ R+ +R +S SR+ V+R+ + R S
Sbjct: 1828 HYEQSVDSSGHSGSHHSHTT---SQERSDVSRGQSGSRS--VSRQTRNEKQSGDGSRHSG 1882
Query: 1972 SRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSR 2031
SR + R SR S V + +S + P T R S S + + S S
Sbjct: 1883 SRHHEASSRADSSRHSQVGQGQS---SGPRTSRNQGSSVSQDSDSQGHSEDSER-WSGSA 1938
Query: 2032 SRTPL---LPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRS 2088
SR L + R SR P + ++S TR + R A+ SS +++
Sbjct: 1939 SRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAA-SSHEQA 1997
Query: 2089 RSATPPATRNHSGSRTPPVALNSSRMS 2115
RS+ A H GS + +SSR S
Sbjct: 1998 RSS---AGERH-GSHHQLQSADSSRHS 2020
Score = 183 bits (465), Expect = 2e-45
Identities = 447/2027 (22%), Positives = 723/2027 (35%), Gaps = 291/2027 (14%)
Query: 15 TNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDI---LDHERKRRVELRCL 71
T G + S + R+G P ++ EE + + K N L RKR
Sbjct: 147 TGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKR------- 199
Query: 72 ELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGG-KEETPGQRPAVTETHQLAELNEK 130
L E +EE+ E+ + + T R+ +K + G Q A T L E N K
Sbjct: 200 -LSERLEEKEDNEEGVYDYENTGRMT--QKWIQSGHIATYYTIQDEAYDTTDSLLEEN-K 255
Query: 131 KNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKK 190
ER R++ G S S V+ S R ++S+ P + + +
Sbjct: 256 IYERSRSSDGKSSSQVNRS-------------------------RHENTSQVPLQESRTR 290
Query: 191 KKKKDR---GRRSESSSPRRERKKSSKKKKHRS----ESESKKRKHRSPTPKSKRKSKDK 243
K++ R R SE S ER S + H +S R RS
Sbjct: 291 KRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSA 350
Query: 244 KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRS---RSAAAKTHTTALAGRSPSPAS 300
R T A S R ++S + A SS R S +SA + H+ G++ S S
Sbjct: 351 DSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVS 410
Query: 301 GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
R G + G+ ++ E + Q S + ++ + S ERS
Sbjct: 411 DRGHRGSS-----GSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSG-- 463
Query: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
R G S ++T ++ R S + + S+S+
Sbjct: 464 ------------RSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQE 511
Query: 421 SPPS----PQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT 476
+ P ++ R S +S + GSH ++S + SHG++ + T
Sbjct: 512 GQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQT 571
Query: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRS 536
+ + + R S HS+ Q R+++ G S S + S
Sbjct: 572 RNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHS 631
Query: 537 PQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRS 596
WS S + G ++ + R SR P RS R G S +R+
Sbjct: 632 EDSERWSGSASRNHHGSAQ--EQSRDGSRHP------RSHHEDRAGHGHSADSSRKSGTR 683
Query: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS--RTPAR 654
T ++ S A ++R+ A R +R ++ SR G++ S R
Sbjct: 684 HT----QNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGH 739
Query: 655 RGRSRSRTPARRGRSRSRTPARRSGRSRS--RTPARRGRSRSRTPRRGRSRSRSLVRRGR 712
RG S S+ G S SG ++ + + +R R+ R R RS S + +
Sbjct: 740 RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSR-RSGSFLYQVS 798
Query: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
+H ++ G +G S+ + S Q +R NS + + R SS R + S
Sbjct: 799 THKQSESSHGWTGPSTGVRQGSHHEQ--ARDNSRHSASQDGQDTIRGHPGSSRRGRQGSH 856
Query: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
SG S + + + RS +S+ ++ SR+ R +R+ +++S+ SR
Sbjct: 857 HEQSVDRSGHSGSHHSHTTS---QGRSDASRGQSGSRSASRTTRN------EEQSRDGSR 907
Query: 833 QS---HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR-SCFESSPDPELKSRTPSR 888
S H +S H + + QG +E S T +R+ S D E S R
Sbjct: 908 HSGSRHHEASSHADISRHSQAGQGQ------SEGSRTSRRQGSSVSQDSDSEGHSEDSER 961
Query: 889 HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948
S S S R+H GS+
Sbjct: 962 WSGSAS---------------------------------RNHRGSAQEQ----------S 978
Query: 949 RSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPS 1008
R S P S+ E R + HS SS + TP ++ SG + +A++ PG
Sbjct: 979 RHGSRHPRSHHEDR--AGHGHSADSSRQS----GTPHAETSSGGQAASSHEQARSSPG-E 1031
Query: 1009 LSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR 1068
GS+ ++S DS S + V+ S G S Q+ S H
Sbjct: 1032 RHGSR----HQQSADSSRHSGIPRRQASSAVRDSGHWGSS---------GSQASDSEGHS 1078
Query: 1069 SDTSSPEVRQSHSESPSLQSKSQTSP--KGGRS-RSSSPVTELASRSPIRQDRGEFSASP 1125
++ + V + P QS +++ GGRS RS S + ++++ G S
Sbjct: 1079 EESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTST 1138
Query: 1126 MLKSGMSPEQSRFQSDSS----------SYP--------------TVDSNSLLGQSRLET 1161
+ G EQ+R S S ++P +VD + G T
Sbjct: 1139 GRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHT 1198
Query: 1162 AESKEKMALPPQEDA-TASPPRQKDKFSPFPVQ---DRPESSLVFKDTLRTPPRERSGAG 1217
A Q + +AS +KDK S + R + + D+ R + +
Sbjct: 1199 TSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSS 1258
Query: 1218 SSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER 1277
S ++ Q S++ S E + E+ A + +H S ++ + E+R
Sbjct: 1259 GSRTSRHQGSSVSQDSDSERHSDDSERLSGSASR--NHHGSSREQSRDGSRHPGFHQEDR 1316
Query: 1278 PAVSLTLDQS--------QSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG- 1328
+ + D S +S + +AV A S G H++ ++S R + G
Sbjct: 1317 ASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS-RHSGIGH 1375
Query: 1329 --SPLEFRNSGPLGTEMNTGFSSE-VKEDLNGPFLN-QLETDPSLDMKEQSTRSSGHSSS 1384
+ R+SG G+ + +SE ED + ++ + P ++S R SS
Sbjct: 1376 RQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESS 1435
Query: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS------SSASSPEMKDGLPRTPSRR 1438
S + + +SS++ S P T R+ S +S+ +DG + R
Sbjct: 1436 GRSRSFLYQ--VSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDG---QDTIR 1490
Query: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECD--SSPEPKALPQTPRPR 1496
GSS G R GS SG S G TP +GRS+ S A QT
Sbjct: 1491 GHPGSSRGGRQGSYHEQSVDRSGHS-GYHHSHTTP-QGRSDASHGQSGPRSASRQTRNEE 1548
Query: 1497 SRSPSSPELNNKCLTPQ-RERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555
S ++ P R S S V Q A + +R S SQ+ D + + E
Sbjct: 1549 QSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSE 1608
Query: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVD--------SKSRLSPRR----SRSGSSPE 1603
R +S + R R SR+ S + D SR S R S G +
Sbjct: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAAS 1668
Query: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSG--SSSKGRGPSPEGSSSTESSPEH 1661
+++ R++P + GS + RR S S RG S +S +E E
Sbjct: 1669 SQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEE 1728
Query: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS----SSPETR 1717
+ G ++ P ++ + + RS + ++S +S S + P T
Sbjct: 1729 SDTQSVSAHG-QAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTG 1787
Query: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRS-RSR 1776
R RH ++ S +++ + + R S SR GR S + + S S
Sbjct: 1788 GRQRSRHEQARDSSRHSASQEGQDTIRGHPGS-------SRGGRQGSHYEQSVDSSGHSG 1840
Query: 1777 SRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTR--RRRGGSGYHSRSPARQESSRTS 1834
S T + R D SR + SRS SR TR ++ G HS S + SSR
Sbjct: 1841 SHHSHTTSQERSD-------VSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRAD 1893
Query: 1835 SRRR----RGRSRTPPTSRKRSRSRTSPAP----------WKRSRSR---ASPATHRRSR 1877
S R +G+S P TSR + S + + W S SR S R
Sbjct: 1894 SSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDG 1953
Query: 1878 SRTPLISRR-RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923
SR P R+ S S R+S +R + + R ++ +S R S
Sbjct: 1954 SRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSS 2000
Score = 174 bits (440), Expect = 1e-42
Identities = 586/2782 (21%), Positives = 932/2782 (33%), Gaps = 372/2782 (13%)
Query: 178 SSSRSPTPKQKKKKKKKDRGRRSES--------------SSPRRERKKSSKKKKHRSES- 222
S SRS + + +K K+ D R S S S +E+ S+ +H+ S
Sbjct: 1211 SGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSV 1270
Query: 223 --ESKKRKHRSPTPK----SKRKSKDKKRKRSRSTTPAP---KSRRAHRSTSADSASSSD 273
+S +H + + + R R++SR + P + RA SADS+ S
Sbjct: 1271 SQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSG 1330
Query: 274 TSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSS 333
T + S S + A SP G R + A S ++ SS A +
Sbjct: 1331 THHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS---AVRDSGH 1387
Query: 334 PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP 393
+ + + S + S+ G P G S + + V+
Sbjct: 1388 RGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSS 1447
Query: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453
++ T ++ P + + Q S E + S SRH++S PGS R
Sbjct: 1448 HEQSESTHGQTAPSTGGR--QGSRHEQARNS------SRHSASQDGQDTIRGHPGSSRGG 1499
Query: 454 SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQW 513
+ HSHT + + + R SR ++ SR
Sbjct: 1500 RQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGS 1559
Query: 514 RRSRSAQRWGRSRSPQ----RRGRSRSPQRPGWSRSRNTQRRGRSR-SARRGRSHSRSPA 568
R + R G SR Q S++ +R G S S++ G S S RR S SR+
Sbjct: 1560 RHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHY 1619
Query: 569 TRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR 628
R +SR +R RS A + + + +R + G++ S R S
Sbjct: 1620 GSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGE 1679
Query: 629 SPVRRRSRSRSPARRSGRSRSRTPA------RRGRSRSRTPARRGRSRSRTPARRSGRSR 682
R +S + SG R + + RG S S+ G S S +
Sbjct: 1680 RHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQ 1739
Query: 683 ------SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT 736
S + RG+S R+ R G S + + +H ++ GR+G S+ + +SR
Sbjct: 1740 AGPHQQSHQESTRGQSGERSGRSG-----SFLYQVSTHEQSESAHGRTGPSTGGRQRSRH 1794
Query: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR 796
Q R S S + + R SS + S +S+ S S T +
Sbjct: 1795 EQARDSSRHSASQEGQ--DTIRGHPGSSRGGRQGSHYE--QSVDSSGHSGSHHSHTTSQE 1850
Query: 797 SRSGSSQPKAKSRTPPRRSRSSSSPPPKQK---SKTPSRQSHSSSSPHPKVKSG------ 847
RS S+ ++ SR+ R++R+ + S+ S + SS H +V G
Sbjct: 1851 -RSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPR 1909
Query: 848 TPPRQGSITSPQANEQSVTPQRRSCFESSPDPEL-----KSRTPSRHSCSGSSPP--RVK 900
T QGS S ++ Q + S+ L +SR SRH S
Sbjct: 1910 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGH 1969
Query: 901 SSTPPRQSPSRSSSPQPKVKAIISPRQ-RSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV 959
S+ RQS +R + + +A S Q RS +G S ++ S + R S ++
Sbjct: 1970 SADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASS 2029
Query: 960 ESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE 1019
R +SGS + D++ E QS V AQ GP K E
Sbjct: 2030 AVRDSGHRGYSGSQASDSEGHSEDSDTQS----------VSAQGKAGPHQQSHK-----E 2074
Query: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS 1079
++ +S S S V S+ ES G S+ G+ + D D+S Q
Sbjct: 2075 SARGQSGESSGRSGSFLYQV-STHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQE 2133
Query: 1080 HSES------PSLQSKS-----QTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
++ PS + Q+ + G S S T RS RG+ + +
Sbjct: 2134 GQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDA--SRGQSGSRSASR 2191
Query: 1129 SGMSPEQSRFQS--------DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASP 1180
EQS S ++SS+ +SL+GQ + +S
Sbjct: 2192 KTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQ-------------------SSG 2232
Query: 1181 PRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELME 1240
PR QD R+ R+ GS+ E S P S
Sbjct: 2233 PRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHH------ 2286
Query: 1241 VVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPS 1300
E+ AG H + ++ T + E+S S QA+ + S
Sbjct: 2287 -----EDRAGH--GHSAESSRQSGTHHAENS---------------SGGQAASSHEQARS 2324
Query: 1301 MASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEV-KEDLNGPF 1359
A G H +S + S + R+SG G+ + SE ED +
Sbjct: 2325 SAGERHGSHHQQSADSSRHSGIGHGQASSAV--RDSGHRGSSGSQASDSEGHSEDSDTQS 2382
Query: 1360 LNQL-ETDPSLDMKEQSTRS-----SGHSSSELSPDAVEKAGMSSN--QSISSPVLDAVP 1411
++ + P ++STR SG S S L + + S++ S+
Sbjct: 2383 VSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSH 2442
Query: 1412 RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR 1471
+R+ S ++S E +D + P GSS G R GS SG S
Sbjct: 2443 HKQARDSSRHSTSQEGQDTIHGHP------GSSSGGRQGSHYEQLVDRSGHSGSHHS--H 2494
Query: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS---ESSVDQKTV 1528
T S+GRS+ SRS S N++ SGS E+S +
Sbjct: 2495 TTSQGRSDASHG----------HSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSS 2544
Query: 1529 ARTPLGQRSRSGS----------SQELDVKPSASPQERSESDSSPDSKAKTRTPLR---- 1574
+ +GQ G SQ+ D + + ER +S + + LR
Sbjct: 2545 GHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSR 2604
Query: 1575 -----QRSRSGSSPEVDSKSRLSPRRSRSGS-----SPEVKDKPRAAPRAQSGSDSSPEP 1624
Q R+G DS + R +++ S S + + A R S S +
Sbjct: 2605 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2664
Query: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRT 1684
+ + S + S RG S +S E E + G S + ++ +
Sbjct: 2665 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQ-QSHQES 2723
Query: 1685 PPRRRSSRSSPELTRKARLSRRSRSASS----SPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
R S + ++S +S SS P TR R RH ++ S ++ +
Sbjct: 2724 ARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQ 2783
Query: 1741 SSRRRRSASSPRTKT--------------------TSRRGRSPSPKPRGLQRSRSRSRRE 1780
+ R SS + T+ +GRS + + + RS SR+ R
Sbjct: 2784 DTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN 2843
Query: 1781 KTRTTRRRDRSGSSQ-------STSRRRQRSRSRSRVTRRRR------------------ 1815
+ ++ SGS SR Q + +S +RR R
Sbjct: 2844 EEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSED 2903
Query: 1816 ----GGSGYHSRSPARQESSRTSSRR-------RRGRSRTPPTSRKRSRSRTSPAPWKRS 1864
GS + + QE R SR R G + +SR+ T + ++
Sbjct: 2904 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQA 2963
Query: 1865 RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS--RTSVTRRRSRSRASPVSRRR 1922
S A + SR S + ++ S R S R S S+AS
Sbjct: 2964 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS 3023
Query: 1923 SRSRTPPVTRR-RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSR---TSPIT 1978
S T V+ ++ S + + +R R+ + T +S S T P T
Sbjct: 3024 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
Query: 1979 RRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLP 2038
R R SR + + SR S + R P + R R S +
Sbjct: 3084 RGRQGSRHE---QAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYH---HEHSVDSSGHSG 3137
Query: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
S + S + RS R G RS +R+ R SG SS S S A+ +
Sbjct: 3138 SHHSHTTS------QGRSDASRGQSGSRSASRTT---RNEEQSGDSSRHSVSRHHEASTH 3188
Query: 2099 HSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMD 2158
SR S S SR S D S G E S R S + GS+ +
Sbjct: 3189 ADISRHSQAVQGQSEGSRRSRRQGSSVSQDS-DSEGHSED--SERWSGSASRNHRGSVQE 3245
Query: 2159 GP--GPRIP-DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV 2215
G R P H H+ R + GT S ++ +P
Sbjct: 3246 QSRHGSRHPRSHHEDRAGHGHSADRSRQS------GTRHAETSSGGQAASSHEQARSSPG 3299
Query: 2216 PLMSLRTAPAANLA--SRIPAASAAAM-----NLASARTPAIPTAVNLADSRTPAAAAAM 2268
R +A+ + S IP A++ + S+ + A + + +S T + +
Sbjct: 3300 ERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHG 3359
Query: 2269 NLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSR 2328
+ + SA + + R+ + + + + +A T + T ++ +R
Sbjct: 3360 QAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQAR 3419
Query: 2329 -------------TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPAL 2375
T + ++ G + +H V+ +G + S + +
Sbjct: 3420 DSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 3479
Query: 2376 SGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP 2435
SG+ S + R S A ++ S SQS P S G +
Sbjct: 3480 SGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSV 3539
Query: 2436 SQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS 2495
SQ + + S R AQ GS+ +S AG + S
Sbjct: 3540 SQDSDSQGHSEDSERWSGSASRNHRGS-AQEQSRDGSRHPTSHH----EDRAGHGHSAES 3594
Query: 2496 VPAPGVPHSD--VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS---S 2550
G H++ G AS+ Q S+ + ++S+ SS S +SS+ S
Sbjct: 3595 SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDS 3654
Query: 2551 SSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSS 2610
SSGS +SDSEG S + S + + + E T + RS S
Sbjct: 3655 GHRGSSGSQASDSEGHSEDSDTQ-------SVSAHGQAGPHQQSHQESTRGRSAGRSGRS 3707
Query: 2611 SSS--SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP 2668
S S+ S S+ + S+ S + SS S ++ G + +
Sbjct: 3708 GSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTI-------RG 3760
Query: 2669 PPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR 2728
PG RR R SY R S +S + GQ G SR
Sbjct: 3761 HPGSRRG------------GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSG-SR 3807
Query: 2729 SPSHKRRRETPSPRPMRHRSSR 2750
S S + R E S RH SR
Sbjct: 3808 SASRETRNEEQSGDGSRHSGSR 3829
Score = 169 bits (429), Expect = 3e-41
Identities = 451/2121 (21%), Positives = 714/2121 (33%), Gaps = 250/2121 (11%)
Query: 177 SSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKH----RSP 232
+S RS + + R R+E S R S+ + S+++S + +S
Sbjct: 550 TSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSS 609
Query: 233 TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALA 292
P++ R + S S + S R S S + S+ +SR S ++H A
Sbjct: 610 GPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQ-EQSRDGSRHPRSHHEDRA 668
Query: 293 GRSPSPASGRR-GEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS 351
G S S R+ G S G ++ + +A ++ S ++ + D S T
Sbjct: 669 GHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHG 728
Query: 352 P-------SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404
S R S+G + +E H + + Q + S RDRS
Sbjct: 729 QASSAVRDSGHRGSSGSQATD-----SEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRS 783
Query: 405 PPKSPE------KLPQSSSSESSP----PSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
+S ++ SESS PS + S H + S A G I
Sbjct: 784 GERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT-IR 842
Query: 455 SSPTSKNR----SHGRAKRDKS------HSHTPS-------RRMGRSRSPATAKRGRSRS 497
P S R SH D+S HSHT S R SRS + R +S
Sbjct: 843 GHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 902
Query: 498 RTPTKRG---------------HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW 542
R ++ HS++ Q SR+++R G S S S W
Sbjct: 903 RDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERW 962
Query: 543 SRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRR 602
S S + RG ++ + R SR P RS R G S +R +S TP
Sbjct: 963 SGSASRNHRGSAQ--EQSRHGSRHP------RSHHEDRAGHGHSADSSR---QSGTPHAE 1011
Query: 603 RSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT 662
S A +P R SR RR S R G S S+
Sbjct: 1012 TSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQA 1071
Query: 663 PARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRS-RSRSLVRRGRSHSRTPQRR 721
G S SG + + + +R GRS RS S + + +H ++
Sbjct: 1072 SDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAH 1131
Query: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG 781
GR+ +S+ R+ S Q R S S + S R + S+ RS
Sbjct: 1132 GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHS 1191
Query: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH 841
S SQ RS +S ++ SR+ R++R ++S SR HS S H
Sbjct: 1192 GSHHSHTTSQ-----GRSDASHGQSGSRSASRQTRKD------KQSGDGSR--HSGSRHH 1238
Query: 842 PKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901
R + Q++ + + S D E S R S S S ++
Sbjct: 1239 EAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSAS-----RN 1293
Query: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVES 961
+ SR S P R+ G S+ S + + T S + S+ ++
Sbjct: 1294 HHGSSREQSRDGSRHPG----FHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQA 1349
Query: 962 RLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKS 1021
R P H ++ HSG + SGS+ + S
Sbjct: 1350 RSSPGERHGSRHQ-------QSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHS 1402
Query: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS 1081
+DS QS P + S+ +GQS S S S + Q S
Sbjct: 1403 EDSDTQS--------VSAHGQAGPHQQSHKESA---RGQSGES----SGRSRSFLYQVSS 1447
Query: 1082 ESPSLQSKSQTSPK-GGRSRSSSPVTELASRSPIRQD-----RGEFSASPMLKSGMSPEQ 1135
S + QT+P GGR S +SR QD RG +S + G EQ
Sbjct: 1448 HEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQ 1507
Query: 1136 SRFQSDSSSY------PTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSP 1189
S +S S Y P S++ GQS +A + + + + S R +
Sbjct: 1508 SVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEP--- 1564
Query: 1190 FPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPA 1249
R SS R + + S ++ Q S++ E E E+ E A
Sbjct: 1565 ---STRAGSS-------RHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESA 1614
Query: 1250 GQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQS--------QSQASLEAVEVPSM 1301
+ +H S ++ + E+R + + + S ++ + +A
Sbjct: 1615 SR--NHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQ 1672
Query: 1302 ASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLN 1361
A S G H++ ++S ++ ++S +G N G S D G +
Sbjct: 1673 ARSSPGERHGSRHQQSADS----STDSGTGRRQDSSVVGDSGNRGSSGSQASDSEG---H 1725
Query: 1362 QLETD-----------PSLDMKEQSTRS-----SGHSSSELSPDAVEKAGMSSNQSISSP 1405
E+D P ++STR SG S S L + + S++ + P
Sbjct: 1726 SEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAH-GRTGP 1784
Query: 1406 VLDAVPRT---PSRERSSSASSPEMKDGLPRTP--SRRSRSGSS-PGLRDGSGTPSRHSL 1459
R+ +R+ S ++S E +D + P SR R GS D SG H
Sbjct: 1785 STGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHS 1844
Query: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR----PRSRSPSSPELNNKCLTPQRE 1515
+S D+ R S RS + K R + S + + Q +
Sbjct: 1845 HTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQ 1904
Query: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP-LR 1574
SG +S +Q + + Q S S E + S S + S+ +R P
Sbjct: 1905 SSGPRTSRNQ----GSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSH 1960
Query: 1575 QRSRSGSSPEVDSKSRLSPRRSRS---GSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA 1631
R+G DS + R + S G + ++ R++ + GS + + +
Sbjct: 1961 HEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHS 2020
Query: 1632 LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSS 1691
++ S+ + G S S H S T ++ P +S R S
Sbjct: 2021 GIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQS 2080
Query: 1692 RSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS-PSVSSPEPAEKSRSSRRRRSASS 1750
S S RS S T ++ H +S PS + + ++ R ++S
Sbjct: 2081 GES---------SGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSAS 2131
Query: 1751 PRTKTT-------SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQR 1803
+ T SR GR S + + + RS T++ R + QS S R
Sbjct: 2132 QEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS----R 2187
Query: 1804 SRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRR----RGRSRTPPTSRKRSRSRTSPA 1859
S SR + + G HS S + SS S R +G+S P TSR R S + +
Sbjct: 2188 SASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDS 2247
Query: 1860 P---WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRAS 1916
R S + R SR SR S R ++ + R+S + +
Sbjct: 2248 DSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHA 2307
Query: 1917 PVSRRRSRSRTPPVTRRRSRSRTPTTRRRS--RSRTPPVTRRRSRSRTPPVTRR-RSRSR 1973
S + + R + R + ++S SR + ++ S R S S+
Sbjct: 2308 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQ 2367
Query: 1974 TSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS--- 2030
S S T V+ + +R R++ + R + +S
Sbjct: 2368 ASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESA 2427
Query: 2031 --RSRTPLLPRKRSRSRSPLAIRRRSRSRT--------PRTARGKRSLTRSPPAIRRRSA 2080
R+ T R+ S + R S S+ P ++ G R + + R
Sbjct: 2428 HGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGH 2487
Query: 2081 SGSSSDRSRS-ATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPL 2139
SGS + S A+ HSGSR+ + S D R G
Sbjct: 2488 SGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSG-----------DGSRHSGSRHHE 2536
Query: 2140 GSSRTPMSVLQQAGGSMMDGP 2160
SSR S Q G +GP
Sbjct: 2537 ASSRADSSGHSQVGQGQSEGP 2557
Score = 160 bits (405), Expect = 2e-38
Identities = 443/2006 (22%), Positives = 672/2006 (33%), Gaps = 246/2006 (12%)
Query: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
D S Q +A +Q E + S S ++ + G+ + S+ R
Sbjct: 2055 DTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGR 2114
Query: 207 R----ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHR 262
+ ++ + S + E + R H P+ ++ S ++ S + S H
Sbjct: 2115 QGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQ-----SVDRSGHSGSHHS 2169
Query: 263 STSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGD--APFSEPGTTSTQR 320
T++ S + +S SRSA+ KT+ +G + E A S +
Sbjct: 2170 HTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQ 2229
Query: 321 PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQP 380
S P T+ + SS +D D + + + R S S R+ H GS Q
Sbjct: 2230 SSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRN----------------HHGSAQ- 2272
Query: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPE-KLPQSSSSESSPPSPQPTKVSRHASSSPE 439
E S R P E + S+ESS S + HA +S
Sbjct: 2273 ---------------EQSRDGSRHPRSHHEDRAGHGHSAESSRQSG-----THHAENS-- 2310
Query: 440 SPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRT 499
A SH + SS ++ SH + D S S + RG S S+
Sbjct: 2311 --SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQA 2368
Query: 500 PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS-AR 558
GHS Q S G++ P ++ S +R R+ R GRS S
Sbjct: 2369 SDSEGHSEDSDTQ-----SVSAHGQA-GPHQQSHQES------TRGRSAGRSGRSGSFLY 2416
Query: 559 RGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR 618
+ +H +S + GR+ + T R+G + AR SR T S+ G S
Sbjct: 2417 QVSTHEQSESAHGRTGTSTGGRQGSHHKQ--ARDSSRHST-----SQEGQDTIHGHPGSS 2469
Query: 619 TPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS--RSRTPAR 676
+ R+ S V R S S + S+ R+ A G S SR+ +R+ R+ +S +R
Sbjct: 2470 SGGRQGSHYEQLVDRSGHSGSHHSHT-TSQGRSDASHGHSGSRSASRQTRNDEQSGDGSR 2528
Query: 677 RSG--------RSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728
SG R+ S ++ G+ +S PR R+ S + S + SGS+S
Sbjct: 2529 HSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSAS 2588
Query: 729 ERKNKSRTSQRRS-----------RSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
+ S Q R R+ SR S R SS A S R
Sbjct: 2589 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS 2648
Query: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR----SRSSSSPPPKQKSKTPSRQ 833
S Q+S R S G Q + R R S++S + + S T S
Sbjct: 2649 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVS 2708
Query: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANE---QSVTPQRRSCFESSPDPELKSRTPSRHS 890
+H + H + + + TS + Q T ++ P + R SRH
Sbjct: 2709 AHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHE 2768
Query: 891 CSGSSPPRVKSSTPP---RQSPSRSSSPQPKVKAIISPRQRSHSGSS------------- 934
+ S S R P S + S HSGS
Sbjct: 2769 QAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 2828
Query: 935 -SPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETP-PRQSH--S 990
S SR SRTT +S + SR +H+ S V+ ++ R+S
Sbjct: 2829 RGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 2888
Query: 991 GSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSC--PGSLSLCAGVKSSTPPGES 1048
S+S + + SGS S +++ L P S +
Sbjct: 2889 SSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR 2948
Query: 1049 YFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS-----------HSESPSLQSKSQTSPKGG 1097
G Q Q + H SS R HS Q+ S G
Sbjct: 2949 QSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH 3008
Query: 1098 RSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQS--DSSSYPTVDSNSLLG 1155
R S S ++ S +D S S ++G S +QS +S S + S S L
Sbjct: 3009 RGYSGSQASDNEGHS---EDSDTQSVSAHGQAG-SHQQSHQESARGRSGETSGHSGSFLY 3064
Query: 1156 Q-SRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERS 1214
Q S E +ES P S Q S R +S +DT+R P
Sbjct: 3065 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSS------RHSASQYGQDTIRGHPGSSR 3118
Query: 1215 GAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPE- 1273
G + + S +S+ GQ S +S + +SS
Sbjct: 3119 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHS 3178
Query: 1274 VEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLE- 1332
V S D S+ +++ S S G S + +S E GS
Sbjct: 3179 VSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRN 3238
Query: 1333 FRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG-----HSSSELS 1387
R S + + ED G + + + T S G H + S
Sbjct: 3239 HRGSVQEQSRHGSRHPRSHHEDRAGHG-HSADRSRQSGTRHAETSSGGQAASSHEQARSS 3297
Query: 1388 PDAVEKAGMSSNQSISSPVLDAVPR-------TPSRERSSSASSPEMKDGLPRTPSRRSR 1440
P E+ G QS S +PR SR SS S +G +S
Sbjct: 3298 PG--ERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSV 3355
Query: 1441 SGSSPG----------LRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP 1490
SG RD SG S S S + GR+ + +
Sbjct: 3356 SGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHH 3415
Query: 1491 QTPRPRSRSPSSPE----LNNKCLTPQRERSGS--ESSVDQKTVA---RTPLGQRSRSGS 1541
+ R SR +S E + + +R R GS E SVD+ + + + RS +
Sbjct: 3416 EQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDA 3475
Query: 1542 SQELDVKPSASPQERSESDSSPDSK--------AKTRTPLRQRSRSGSSPEVDSKSRLSP 1593
S+ SAS Q R++ S S+ A T+ + S+SG P
Sbjct: 3476 SRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSA------GP 3529
Query: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR----ALPRRSRSGS--------S 1641
R SR+ S +D +Q S+ S A R + +SR GS
Sbjct: 3530 RTSRNQGSSVSQDSD-----SQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHED 3584
Query: 1642 SKGRGPSPEGSSST-------------ESSPEHPPKSRTARRGS--RSSPEPKTKSRTPP 1686
G G S E S + SS E S R GS + S + S
Sbjct: 3585 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 3644
Query: 1687 RRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS-PSVSSPEPAEKSRSSRRR 1745
+ SS R + S+ S S S ++ +++ H ++ P S + + + RS+ R
Sbjct: 3645 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 3704
Query: 1746 -RSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQST------S 1798
RS S +T + S + R SR E+ R + R S Q T S
Sbjct: 3705 GRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGS 3764
Query: 1799 RR--RQRSRSRSRVTRRRRGGSGY-HSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR 1855
RR RQ S V R GS + H+ S R ++S S R T + SR
Sbjct: 3765 RRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSR 3824
Query: 1856 TSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS-- 1913
S + + ++A + H +S SRR R +S S + + RRS S
Sbjct: 3825 HSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESAS 3884
Query: 1914 ---RASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970
S + R SR P + R + S ++ +S S T S
Sbjct: 3885 RNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGI 3944
Query: 1971 RSRTSPITRRRSRSRTSPVTRRRSRS 1996
+SR SP + ++ R++ +S
Sbjct: 3945 QSRGSPHSSSSYHYQSEGTERQKGQS 3970
Score = 140 bits (353), Expect = 2e-32
Identities = 474/2140 (22%), Positives = 742/2140 (34%), Gaps = 248/2140 (11%)
Query: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
+R S R R+ + RS++P G +R S S R+G S + + G++
Sbjct: 123 KRPSSLERRNNRKGNKGRSKSPRETGG------KRHESSSEKKERKGYSPTHREEEYGKN 176
Query: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG--- 781
+S +K K++T R N + R+ + + R++ + SG
Sbjct: 177 HHNSSKKEKNKTENTRLGDNR--KRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIA 234
Query: 782 ------SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR-SSSSPPPKQKSKTPSRQS 834
S + S KS + RSR ++S P Q+S+T R+
Sbjct: 235 TYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRG 294
Query: 835 HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894
S + S ++ + + S Q R + S P +S R S S
Sbjct: 295 SRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSR---DGSRHP--RSHDEDRASHGHS 349
Query: 895 SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS 954
+ +S T ++ SR + +A SP +R SG + S S T R ++ S
Sbjct: 350 ADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATG--RGQASS 407
Query: 955 PCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKS 1014
S+ R SGS + D++ E QS SG + ++ SG +S
Sbjct: 408 AVSDRGHR-----GSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERS 462
Query: 1015 PCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD----HRSD 1070
P S G + G + SQ D H
Sbjct: 463 GRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGS 522
Query: 1071 TSSPEVRQSHSESP--SLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
+ H +S S S S S + RS + + SRS RQ R E + +
Sbjct: 523 SRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTR 582
Query: 1129 -SGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
SG ++ Q+DSS + V G S+ + + Q+ + +++
Sbjct: 583 HSGSRHHEASSQADSSRHSQVGQGQSSGPRT-----SRNQGSSVSQDSDSQGHSEDSERW 637
Query: 1188 SPFPVQDRPESSLV-FKDTLRTPP---RERSGAGSSPETKEQNSALPT-SSQDEELMEVV 1242
S ++ S+ +D R P +R+G G S ++ ++ T +S +
Sbjct: 638 SGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSH 697
Query: 1243 EKSEEPAGQILSHLSS-ELKEMSTSNFESSPEVEERPAV-------SLTLDQSQSQASLE 1294
E++ AG+ H S +L+ +S + + AV S + S+ E
Sbjct: 698 EQARSSAGE--RHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSE 755
Query: 1295 AVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKED 1354
+ S++ H H+E + E S R SG +++T SE
Sbjct: 756 DSDTQSVSGHGQAGHHQQSHQESARDRSGERS-------RRSGSFLYQVSTHKQSESSHG 808
Query: 1355 LNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVE-KAGMSSNQSISSPVLDAVPRT 1413
GP + EQ+ +S HS+S+ D + G S S +V R+
Sbjct: 809 WTGPSTGVRQGSHH----EQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRS 864
Query: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLR-----DGSGTPSRHSLSG--SSPGM 1466
S S S G R+ + R +SGS R + S SRHS S +
Sbjct: 865 G---HSGSHHSHTTSQG--RSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSH 919
Query: 1467 KDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQK 1526
DI R G+ + + S +T R R S S + +++ + ER +S + +
Sbjct: 920 ADISRHSQAGQGQSEGS-------RTSR-RQGSSVSQDSDSEGHSEDSERWSGSASRNHR 971
Query: 1527 TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD 1586
A+ ++SR GS P + ++R+ S DS ++ TP + S G +
Sbjct: 972 GSAQ----EQSRHGSRH-----PRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSH 1022
Query: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
++R SP R GS R Q +DSS +PRR S S+ + G
Sbjct: 1023 EQARSSPGE-RHGS------------RHQQSADSSRHS------GIPRRQAS-SAVRDSG 1062
Query: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR-----RSSRSSPELTRKA 1701
S S H +S T P +S R RS RS + +
Sbjct: 1063 HWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQ-- 1120
Query: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRG- 1760
+S +S S+ TR+ T R + + SR S + + R SRRG
Sbjct: 1121 -VSTHEQSESAHGRTRTSTGRRQ----GSHHEQARDSSRHSASQEGQDTIRAHPGSRRGG 1175
Query: 1761 RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRR--GGS 1818
R S + + RS T++ R + QS SR S SR TR+ + G
Sbjct: 1176 RQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSR------SASRQTRKDKQSGDG 1229
Query: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878
HS S + +S S R + + + SR + S R S + R S S
Sbjct: 1230 SRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGS 1289
Query: 1879 RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
SR S SR +SR + RAS SR S S
Sbjct: 1290 A----SRNHHGS-----SREQSRDGSRHPGFHQEDRASH-GHSADSSRQSGTHHTESSSH 1339
Query: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
++R+ P R SR + + SR S I R++ S R S
Sbjct: 1340 GQAVSSHEQARSSPGERHGSRHQ-----QSADSSRHSGIGHRQASSAVRDSGHRGSSG-- 1392
Query: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPL---AIRRRSR 2055
S VT S S + + P + S RSRS L + +S
Sbjct: 1393 SQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSE 1452
Query: 2056 SRTPRTA--RGKRSLTRSPPAIR--RRSASGSSSDRSRSATPPATRNHSGSRTPPVALNS 2111
S +TA G R +R A R SAS D R P ++R +++
Sbjct: 1453 STHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGH-PGSSRGGRQGSYHEQSVDR 1511
Query: 2112 SRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTS 2171
S S + +P S G P +SR + Q GS R S
Sbjct: 1512 SGHSGYHHSHTTPQGRSDA-SHGQSGPRSASRQTRNEEQSGDGS-------------RHS 1557
Query: 2172 VPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASR 2231
+H S A + +G S ++ + +SQ R + + S
Sbjct: 1558 GSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQD---------RDSEGHSEDSE 1608
Query: 2232 IPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPT 2291
+ SA+ + SAR + + N + A+ + S R + A + + +
Sbjct: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAAS 1668
Query: 2292 AP--AVNLAGARTPAA--LAALSLTGSGT---PPTAANYPSSSRTPQAPASANLVGPRSA 2344
+ A + G R + +A S T SGT ++ S +R +++ G
Sbjct: 1669 SQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEE 1728
Query: 2345 HATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYER---VSGRTSPPL 2401
T V+ G A + S R S +S +E+ GRT P
Sbjct: 1729 SDTQSVSAHGQ--AGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPST 1786
Query: 2402 LDRARSRTPPSAPSQSRMTSE------RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAF 2455
R RSR + S S+ R SSR G+ S +Q +
Sbjct: 1787 GGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH------YEQSVDSSGHSG 1840
Query: 2456 SDQSRCLIAQTTPVAGSQSLSSGAVATTTSS--AGDHNGMLSVPAPGVPHSDVGEPPAST 2513
S S + + V+ QS S T + +GD G HS AS+
Sbjct: 1841 SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGD----------GSRHSGSRHHEASS 1890
Query: 2514 GAQQP--SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571
A S + Q + R S + SS S S S S S SGS+S + GS+
Sbjct: 1891 RADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAW--- 1947
Query: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631
R S P R G A R+S + + SSS ++SS + SS+
Sbjct: 1948 ---EQSRDGSRHPGSHHEDRAGHGHS---ADSSRQSGTRHTESSSRGQAASSHEQARSSA 2001
Query: 2632 SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSL 2691
S S+ SS S G + S + G + S S DS D++S+
Sbjct: 2002 GERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDS--DTQSV 2059
Query: 2692 SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
S + P Q S + S RGQ G+S S
Sbjct: 2060 S--------AQGKAGPHQQ----SHKESARGQSGESSGRS 2087
Score = 132 bits (332), Expect = 5e-30
Identities = 375/1733 (21%), Positives = 564/1733 (32%), Gaps = 227/1733 (13%)
Query: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
D S +A +Q E + S R S ++ + GR S+ R
Sbjct: 2379 DTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGR 2438
Query: 207 R--ERKKSSKKKKHRSESESKKRKHRSPTPKSK-RKSKDKKRKRSRSTTPAPKSRRAHRS 263
+ K++ +H + E + H P S R+ ++ RS S H
Sbjct: 2439 QGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSG----HSGSHHSH 2494
Query: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323
T++ S + S SRSA+ +T +G + R E + G + + S
Sbjct: 2495 TTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQS 2554
Query: 324 --PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381
P T+ SS +D D + + R S S R+ G RH S Q
Sbjct: 2555 EGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRD--GSRHPRSHQED 2612
Query: 382 ATTPLSQEPVNPPSEASPTRDRS---PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
+ S T+ S S E+ S+ Q SRH+
Sbjct: 2613 RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2672
Query: 439 ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR 498
A HR S S S N H +S S G++ S + + +R R
Sbjct: 2673 GQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVS-----AHGQAGSHQQSHQESARGR 2727
Query: 499 TPTKRGHSRSRSPQ---WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRR---- 551
+ GHS S Q +S S+ W P RGR S SR++ +
Sbjct: 2728 SGETSGHSGSFLYQVSTHEQSESSHGW---TGPSTRGRQGSRHEQAQDSSRHSASQDGQD 2784
Query: 552 ------GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605
G SR R+G H S + G S G S T S+
Sbjct: 2785 TIRGHPGSSRGGRQGYHHEHSVDSSGHS--------GSHHSHTT--------------SQ 2822
Query: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
R+ A RG+S SR+ +R R +S +R SG SR + A
Sbjct: 2823 GRSDASRGQSGSRSASRT-------TRNEEQSGDGSRHSGSRHHEASTHADISR-HSQAV 2874
Query: 666 RGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSG 725
+G+S +RR G S S+ G S G + R+H + Q + R G
Sbjct: 2875 QGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA--------SRNHHGSAQEQLRDG 2926
Query: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC 785
S R S + R+ SR S R SS A S R S
Sbjct: 2927 SRHPR------SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGS 2980
Query: 786 PKQKSQTPPRRSRSGSSQPKAKSRTPPRR----SRSSSSPPPKQKSKTPSRQSHSSSSPH 841
Q+S R S G Q + R R S++S + + S T S +H + H
Sbjct: 2981 HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSH 3040
Query: 842 PKVKSGTPPRQGSITSPQANE---QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898
+ + + TS + Q T ++ P + R SRH + S
Sbjct: 3041 QQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRH 3100
Query: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
S S + + SG S S TS+ SR
Sbjct: 3101 SASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRG------ 3154
Query: 959 VESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ 1018
SGS S + E S S+S + + A T S
Sbjct: 3155 ----------QSGSRSASRTTRNEEQSGDSSRHSVSRHHE--ASTHADISRHSQAVQGQS 3202
Query: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH--RSDTSSPEV 1076
E S+ S Q S+S + + + E + G +S +G Q H R S E
Sbjct: 3203 EGSRRSRRQG--SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHED 3260
Query: 1077 RQSHSESPSLQSKSQT----SPKGGRSRSS------SPVTELASRSPIRQDRGEFSASPM 1126
R H S +S T + GG++ SS SP SR D S P
Sbjct: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPR 3320
Query: 1127 LKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDK 1186
++ + SR S S + DS +S ++ S A P Q+ S +D+
Sbjct: 3321 GQASSAVRDSRHWGSSGSQAS-DSEGHSEESDTQSV-SGHGQAGPHQQSHQESA---RDR 3375
Query: 1187 FSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSE 1246
R S F + T + S G + + + S E+ + S
Sbjct: 3376 SG-----GRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQG----SHHEQARDSSRHSA 3426
Query: 1247 EPAGQ--ILSHLSSELKEMSTSNFESSPEVEERPAV--SLTLDQSQSQASL-------EA 1295
GQ I H S + S++E S + S T Q +S AS +
Sbjct: 3427 SQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3486
Query: 1296 VEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDL 1355
+ + S G S H +++ + + +++GP T N G S D
Sbjct: 3487 RQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPR-TSRNQGSSVSQDSDS 3545
Query: 1356 NGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPS 1415
G E S R SG +S A E++ S S D S
Sbjct: 3546 QGH-------------SEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHE-DRAGHGHS 3591
Query: 1416 RE--RSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGS-----GTPSRHSLSGSSPGMKD 1468
E R S E G + S ++ SS G R GS SRHS G
Sbjct: 3592 AESSRQSGTHHAENSSG-GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSA 3650
Query: 1469 IPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528
+ + RG S +S S + + + ++ + + S + T
Sbjct: 3651 VRDSGHRGSSGSQASDS-------------EGHSEDSDTQSVSAHGQAGPHQQSHQESTR 3697
Query: 1529 ARTPLGQRSRSGSSQELDVKPSASPQERSES------DSSPDSKAKTRTPLRQRSRSGSS 1582
R+ G+ RSGS S E+SES S+ + R SR +S
Sbjct: 3698 GRSA-GRSGRSGSFLY-----QVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSAS 3751
Query: 1583 PEVDSKSRLSPRRSRSGSSPEVKDKP-------------------RAAPRAQSGSDSSPE 1623
E R P R G ++ A QSGS S
Sbjct: 3752 QEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRS--- 3808
Query: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683
A R +SG S+ G +S+ S H + GSR S + +
Sbjct: 3809 ----ASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRS---RRQGS 3861
Query: 1684 TPPRRRSSRSSPE-LTRKARLSRRSRSASSSPETR--SRTP-PRHRRSPSVSSPEPAEKS 1739
+ + S + PE R++ + R+ SS ++R SR P HR + S P +
Sbjct: 3862 SVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSD 3921
Query: 1740 RSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSG 1792
S+ + S ++ ++ S RG S S + T R++ +SG
Sbjct: 3922 SSTAKEHGHFSSLSQDSAYHSGIQS---RGSPHSSSSYHYQSEGTERQKGQSG 3971
Score = 48.1 bits (113), Expect = 1e-04
Identities = 57/221 (25%), Positives = 81/221 (36%), Gaps = 29/221 (13%)
Query: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
SS S++ +SS+ S SSGS +SDSEG S + S + K +R
Sbjct: 394 SSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQ-------SVSGHGKAGLR 446
Query: 2592 EGRPPEPTPAKRKRRSSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
+ E T + RS S SS S+ S+ + +S+ S + SS
Sbjct: 447 QQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRH 506
Query: 2650 SPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRD 2709
S ++ G + + PG S R R S+ R S
Sbjct: 507 SASQEGQDTI-------RGHPG------------SSRGGRQGSHHEQSVNRSGHSGSHHS 547
Query: 2710 QQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
+S + GQ G SRS S + R E S RH SR
Sbjct: 548 HTTSQGRSDASHGQSG-SRSASRQTRNEEQSGDGTRHSGSR 587
Score = 45.8 bits (107), Expect = 6e-04
Identities = 65/269 (24%), Positives = 98/269 (36%), Gaps = 30/269 (11%)
Query: 2487 AGDHNGMLSVPAPGVPHSDV--GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
AG + S G PH++ G AS+ Q S+ ++ ++S+ SS S
Sbjct: 993 AGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRR 1052
Query: 2545 SSSSSSSSSS---SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPA 2601
+SS+ S SSGS +SDSEG S S T + ++G P + +
Sbjct: 1053 QASSAVRDSGHWGSSGSQASDSEGHS-----------EESDTQSVSGHGQDG-PHQQSHQ 1100
Query: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
+ R S S S S S+ S S+ + +S+ S + A +
Sbjct: 1101 ESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE 1160
Query: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
+ PG RR R S+ R S +S +
Sbjct: 1161 GQDTIRAHPGSRRG------------GRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASH 1208
Query: 2722 GQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
GQ G SRS S + R++ S RH SR
Sbjct: 1209 GQSG-SRSASRQTRKDKQSGDGSRHSGSR 1236
Score = 45.4 bits (106), Expect = 8e-04
Identities = 92/388 (23%), Positives = 138/388 (35%), Gaps = 52/388 (13%)
Query: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS-AFSDQSRCLIAQ 2465
SR S+ SQ SER S R+ + S++ +++Q R F + R
Sbjct: 1263 SRHQGSSVSQDS-DSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGH 1321
Query: 2466 TTPVAGSQSLSSGAVATTTSSAGD----HNGMLSVPAP--GVPHSDVGEPPASTGAQQPS 2519
+ S SG T +SS G H S P G H + +G
Sbjct: 1322 SA----DSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQ 1377
Query: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS-------------SSGSSSSDSEGS 2566
A +A++ + R SS S ++S S S + S S+ S+ S +S G
Sbjct: 1378 ASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437
Query: 2567 SLPVQPEVALKRVPSPT---PAPKEAVREGRPPEPTPAKRKRRSSSSSSS---------S 2614
S +V+ T AP R+G E A+ R S+S S
Sbjct: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQ--ARNSSRHSASQDGQDTIRGHPGS 1495
Query: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA-SPKKPPPGER 2673
S S S S S S ++ S S + GP++ + + ++ G R
Sbjct: 1496 SRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSR 1555
Query: 2674 RSRS----PRKPIDSLRDSR----SLSYSPVERRRPSPQPSPRDQQ--SSSSERGSRRGQ 2723
S S P S R S+ + S RR+ S RD + S SER S
Sbjct: 1556 HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615
Query: 2724 RGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
R S + R + +PR H+ R+
Sbjct: 1616 RNHYGSAREQSRHGSRNPRS--HQEDRA 1641
Score = 42.7 bits (99), Expect = 0.005
Identities = 68/286 (23%), Positives = 105/286 (36%), Gaps = 33/286 (11%)
Query: 2476 SSGAVATTTSSAGDHNGMLSVPAPGV--PHSDVGEPPA---STGAQQPSALAALQPAKER 2530
SSG+ A+ + + + SV A G PH + S G S Q +
Sbjct: 3659 SSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHE 3718
Query: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
+S S+ + S+ S + S S S+ ++ P +
Sbjct: 3719 QSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGH----------PGSRRGG 3768
Query: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
R+G E + + S S ++S S +S S S S+S + + S S S S
Sbjct: 3769 RQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGS 3828
Query: 2651 ---PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
A + S + G RRSR R+ +DS S +Y P+ S
Sbjct: 3829 RHHEASTQADSSRHSQSGQGESAGSRRSR--RQGSSVSQDSDSEAY---------PEDSE 3877
Query: 2708 RDQQSSS-SERGSRRGQ-RGDSRSP--SHKRRRETPSPRPMRHRSS 2749
R +S+S + GS R Q R SR P SH+ P++ SS
Sbjct: 3878 RRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSS 3923
Score = 42.4 bits (98), Expect = 0.006
Identities = 77/352 (21%), Positives = 122/352 (34%), Gaps = 31/352 (8%)
Query: 2417 SRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLS 2476
SR + R SSR GQA S + +Q RS + A ++ +G +
Sbjct: 1974 SRQSGTRHTESSSR-GQAAS------SHEQARSSAGERHGSHHQLQSADSSRHSG---IG 2023
Query: 2477 SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPA--STGAQQPSALAALQPAKERRSSS 2534
G ++ +G S + HS+ + + + G P + + A+ + S
Sbjct: 2024 HGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGES 2083
Query: 2535 SSSSSS----------SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP 2584
S S S S S+ S+ S+ GS ++ SS + + P
Sbjct: 2084 SGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGH-P 2142
Query: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
P R+G E + R S S S ++S S +S S S S+S + S
Sbjct: 2143 GPSRGGRQGSHQEQSV---DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQS 2199
Query: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPR--KPIDS--LRDSRSLSYS-PVERR 2699
S +A S + G+ +S PR +P S +DS S +S ERR
Sbjct: 2200 GDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERR 2259
Query: 2700 RPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
S + S GSR + H E+ H + S
Sbjct: 2260 SGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSS 2311
Score = 40.8 bits (94), Expect = 0.019
Identities = 99/446 (22%), Positives = 151/446 (33%), Gaps = 61/446 (13%)
Query: 2315 GTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPA 2374
G P ++ S Q+ + G +H T+ S + AS + +
Sbjct: 518 GHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQS 577
Query: 2375 LSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP-----SS 2429
G + R ++ + S R S + + +S P ++ +Q S+ + S S
Sbjct: 578 GDGTRHSGSRHHEASSQADSSRHSQ--VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSE 635
Query: 2430 RMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG-----SQSLSSGAVATTT 2484
R + S++ AQ+Q R D SR + AG S SG T
Sbjct: 636 RWSGSASRNHHGSAQEQSR--------DGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQN 687
Query: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
SS+G + E S+ ++ + LQ A SS S + +S
Sbjct: 688 SSSGQA-------------ASSHEQARSSAGERHGSRHQLQSAD---SSRHSGTGHGQAS 731
Query: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604
S+ S SSGS ++DSEG S + + V A +R
Sbjct: 732 SAVRDSGHRGSSGSQATDSEGHS----EDSDTQSVSGHGQAGHHQQSHQESARDRSGERS 787
Query: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664
RRS S S+ S SS + S+ S + +S S ++ G +
Sbjct: 788 RRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRH-SASQDGQDTI----- 841
Query: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQR 2724
+ PG S R R S+ R S +S + RGQ
Sbjct: 842 --RGHPG------------SSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQS 887
Query: 2725 GDSRSPSHKRRRETPSPRPMRHRSSR 2750
G SRS S R E S RH SR
Sbjct: 888 G-SRSASRTTRNEEQSRDGSRHSGSR 912
Score = 39.7 bits (91), Expect = 0.041
Identities = 49/201 (24%), Positives = 67/201 (33%), Gaps = 30/201 (14%)
Query: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
S SS SSS + S S +P+Q KR S +++ E R
Sbjct: 260 SRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASR 319
Query: 2606 RSSSSSSSSSSSSS----SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
S+ S S S +S S+ SS S + + +SS A QA
Sbjct: 320 NHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQA--- 376
Query: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
+ PGER ++ DS R S + R Q SS+ R
Sbjct: 377 -----RSSPGERHGSGHQQSADSSRHS----------------ATGRGQASSAVSDRGHR 415
Query: 2722 GQRGDSRSPS--HKRRRETPS 2740
G G S S H +T S
Sbjct: 416 GSSGSQASDSEGHSENSDTQS 436
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
Length = 2365
Score = 172 bits (435), Expect = 5e-42
Identities = 332/1434 (23%), Positives = 536/1434 (37%), Gaps = 215/1434 (14%)
Query: 1387 SPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPG 1446
SPD+ S++ S+ ++ R+ + S E+ +PR P R+ SS
Sbjct: 137 SPDSATPDDTSNSSSVDWDTVE-------RQEEEAPSWDELAVMIPRRPREGPRADSS-- 187
Query: 1447 LRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELN 1506
+ +R + G + G K T GRS A R R S S E +
Sbjct: 188 -QRAPSLLTRSPVGGDAAGQKK-EDTGGGGRS---------AGQHWARLRGESGLSLERH 236
Query: 1507 NKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSK 1566
LT + S + S + T ++ QR + ++ ++ ++SP ++ D+S S
Sbjct: 237 RSTLT--QASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASS 294
Query: 1567 AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA------PRAQSGSDS 1620
+ ++ SR+ S+ + S++ + + SS + +D PRA+ PRA S S S
Sbjct: 295 TQ-----QEISRASSTQQETSRASSTQEDTPRASSTQ-EDTPRASSTQWNTPRASSPSRS 348
Query: 1621 S------------PEPKAPAPRALPRRSR----------SGSSSKGRGPSPEGSSSTESS 1658
+ P+ P P+R +SS R E S ++ +
Sbjct: 349 TQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQ 408
Query: 1659 PEHPPKSRTA--RRGSRSSPEPKTKSRTPPR----RRSSRSSPELTRKARLSRRSRSASS 1712
++P SRT+ R +R +P R PR R++R +P + R + R+ S +S
Sbjct: 409 RDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRA-SRTS 467
Query: 1713 SPETRSRTPPR----HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768
SP +R PR R +P SSP A + + +PR TS R+ PR
Sbjct: 468 SPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPR 527
Query: 1769 GLQRSRSRSRREK-TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPAR 1827
R R R R + +Q + R R+ S +R TR S A+
Sbjct: 528 TSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDN------PRTSCAQ 581
Query: 1828 QESSRTSSRRRRGRSRTPPTSRKRSRSR----TSPAPWKRSRSRASPATHRRSRSRTPLI 1883
+++ R SS R R + +R R +SP R R S A R+ +P
Sbjct: 582 RDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNR 641
Query: 1884 SRRRSRSRTSPVSRRRSR-SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTT 1942
+ ++ RTS R R S + T ++ R S R R+ +P T ++ RT
Sbjct: 642 TTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCA 701
Query: 1943 RRRS-RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPV 2001
+R R+ +P T ++ RT R R+ + T +R RTS R R+ +
Sbjct: 702 QRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNR 761
Query: 2002 TRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT--- 2058
T ++ RTS TR+ + + P R RT R R+ SP+ ++ RT
Sbjct: 762 TIQQENLRTS-CTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQ 820
Query: 2059 ---PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
PR++ ++ ++ +R + + + R R+ + R++ G+ + +
Sbjct: 821 QNIPRSSSTQQDNPKT-SCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENL- 878
Query: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN 2175
RPS SP + +P P +++ + DGP RTS P
Sbjct: 879 ---RPS-SPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGP--------RTSSPSR 926
Query: 2176 HAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235
QS + A A+ T P S+ A+ P S NL SR ++
Sbjct: 927 SKQSEVPWASIALR-PTQGDRPQTSSPSRPAQHD------PPQSSFGPTQYNLPSRATSS 979
Query: 2236 SAAAMNLASART--PAIPTA-----VNLADSRTPAAAAAMNLASPRTAVAPSAVN----- 2283
S + +++RT P P A + S+ P A + +PR + P +
Sbjct: 980 SHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFP 1039
Query: 2284 -LADPRTPTA-----------PAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQ 2331
+PR P + PAV + P A + T P + + Q
Sbjct: 1040 FFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQ 1099
Query: 2332 APASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYE 2391
+P L P APV I G R AP + + R AP P +
Sbjct: 1100 SPQHEPLQLP------APVCI-GYRD----APRASSPPRQAP--------EPSLLFQDLP 1140
Query: 2392 RVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPV 2451
R S + P +D P P+ + APS SS QAP SL QD P + +
Sbjct: 1141 RASTESLVPSMDSLHE--CPHIPTPVCIGHRDAPSFSSPPRQAPEPSLF--FQDPPGTSM 1196
Query: 2452 PSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPA 2511
S +A +T S H + +P + H D P A
Sbjct: 1197 ES--------------------------LAPSTDSL--HGSPVLIPQVCIGHRDA--PRA 1226
Query: 2512 STGAQQ-PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570
S+ + PS LA L P S S SS S S+ G + + E V
Sbjct: 1227 SSPPRHPPSDLAFLAP--------------SPSPGSSGGSRGSAPPGETRHNLEREEYTV 1272
Query: 2571 QPEV-ALKRVPSPTPAPK-EAVREGRPPEPTPAK------RKRRSSSSSSSSSSSSSSSS 2622
++ +R+ P P+ + GR P A+ ++RR S ++ + + S
Sbjct: 1273 LADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRS 1332
Query: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSP----AKPGPQALPKPASPKKPPPGERRSR-S 2677
S S SS + S + P+ + P P SP+K P G+R+ + S
Sbjct: 1333 QQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGS 1392
Query: 2678 PRKPIDSLR--DSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRS 2729
P P S R + + P+E + P+ QS GS+ R RS
Sbjct: 1393 PLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERS 1446
Score = 167 bits (424), Expect = 1e-40
Identities = 435/2032 (21%), Positives = 702/2032 (34%), Gaps = 312/2032 (15%)
Query: 161 KQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK---KK 217
++P P S S +RSP +KK+D G S+ R + ++
Sbjct: 176 RRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLER 235
Query: 218 HRSE--SESKKRKHRSPTPKSKRKSKDKK-RKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
HRS S H P + + S ++ ++ ST P++ HR T D++ +S T
Sbjct: 236 HRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASST 295
Query: 275 SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334
+ SR+++ + T+ + + D P + +T R SSP +T+ +
Sbjct: 296 QQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPR 355
Query: 335 YEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP 394
+D + S P+ +P+R + P P + SP S+
Sbjct: 356 TSSTQQDNPQTSF--PTCTPQREN----PRTPCVQQDDPRASSPNRTTQRENSRTSCAQR 409
Query: 395 SEASPTRDRSPPKSPEKLPQSSSSE-SSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453
+R SP ++ P++S ++ +P + P++ +R ++ + + P
Sbjct: 410 DNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASR---- 465
Query: 454 SSSPTSKNRSHGR---AKRDKSHSHTPSR----------------RMGRSRSPATAKRGR 494
+SSP R + R A+RD + +PSR R R+ SP A R
Sbjct: 466 TSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDN 525
Query: 495 SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT-QRRGR 553
R+ + +R + R+ SP + R R R+ SP R R + +R
Sbjct: 526 PRT-SCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDN 584
Query: 554 SRSARRGRSHSRSPATR-------GRSRSRTPARRGRSRSRTPARRRS--RSRTPTR--- 601
R++ R+ +P T SR+ +P R R RT +R R+ +P R
Sbjct: 585 PRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQ 644
Query: 602 ----RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP-ARRG 656
R S +R R S +RT + RT +R R+ SP+R + RT A+R
Sbjct: 645 QDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRD 704
Query: 657 RSRSRTP-------------ARRGRSRSRTPARRSGRSRSRTP-ARRGRSRSRTPRRGRS 702
R+ +P ARR R+ + R R RT A+R R+ +P R
Sbjct: 705 DPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQ 764
Query: 703 RSR---SLVRRGRSHSRTPQRRGRSG---SSSERKNKSRTSQRRSRSNSSPE-MKKSRIS 755
+ S R+ + +P R R S ++R N +S R+ +P + I
Sbjct: 765 QENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIP 824
Query: 756 SRRSRSLSSPRSKAKSRLSLRRSL-----------------SGSSPCPKQKSQTPPRRSR 798
S +P++ R +LR + + SS C QK P
Sbjct: 825 RSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPH 884
Query: 799 SGSSQPKAKSRTPPRRSRS---SSSP--PPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG 853
+ ++ +P R ++ +S P P + S S S S P P QG
Sbjct: 885 RSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQG 944
Query: 854 SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST--PPRQSPSR 911
PQ + S Q DP S P++++ P R SS+ P QS SR
Sbjct: 945 D--RPQTSSPSRPAQH--------DPPQSSFGPTQYNL----PSRATSSSHNPGHQSTSR 990
Query: 912 SSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSG 971
+SS P A S S P + R PR S SP ++ P +
Sbjct: 991 TSS--PVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRAS---SPPRYLQHDPFPFFPE-- 1043
Query: 972 SSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPG----------PSLSGSKSPCPQEKS 1021
+P+++ PP + I +A +PP P S ++ C Q
Sbjct: 1044 PRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQC-QSPQ 1102
Query: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD---------HRSDTS 1072
+ L P + ++S+PP ++ SL + + S + H
Sbjct: 1103 HEPLQLPAPVCIGYRDAPRASSPPRQA--PEPSLLFQDLPRASTESLVPSMDSLHECPHI 1160
Query: 1073 SPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML--KSG 1130
V H ++PS S + +P+ P T + S +P SP+L +
Sbjct: 1161 PTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAP---STDSLHGSPVLIPQVC 1217
Query: 1131 MSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQED------------ATA 1178
+ + S +P D + L S + + + PP E A
Sbjct: 1218 IGHRDAPRASSPPRHPPSDL-AFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADL 1276
Query: 1179 SPPRQKDKFSPFPVQD-----------RPESSLVFKDTLRTPPRERSGAGSSPETKEQNS 1227
PPR+ + P P R E +F R+ AG+ E S
Sbjct: 1277 PPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQ----ERRKSEAAGAFQAQDEGRS 1332
Query: 1228 ALPTSSQDEELMEVVEKSEEPAGQI--LSHLSSELKEMSTSNFESSPEVEERPAVSLTLD 1285
P+ Q + L + S P+ Q+ L +EL S + E+RP
Sbjct: 1333 QQPSQGQSQLLRR--QSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRP------- 1383
Query: 1286 QSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNT 1345
+ L+ +P S + +P RE PLE +GP
Sbjct: 1384 --EGDRQLQGSPLPPRTS--------------ARTPERELRTQRPLESGQAGP------- 1420
Query: 1346 GFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP 1405
++ L G + +Q E S RS L P G S + +P
Sbjct: 1421 ------RQPL-GVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAP 1473
Query: 1406 VLDAVPRTPSRERSSSASSPEMKD-----GLPRTPSRRSRSGSSPGLRDGSGTPSRHSLS 1460
+ SRE S PE + LPR +RS S P + G P+ S S
Sbjct: 1474 --EGAWGGTSREYKESWGQPEAWEEKPTHELPRELGKRSPLTSPP---ENWGGPAESSQS 1528
Query: 1461 GSSPGMKDIPRTPSR-GRSECDSSPEPKALPQTPRPRSRS----PSSPELNNKCLTPQRE 1515
S TP+ G + P P+ + P R +P P +
Sbjct: 1529 WHS-------GTPTAVGWGAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLD 1581
Query: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDV-KPSASPQERSESDSSPDSKAKTRTPLR 1574
G + + + P G R + ++ P + ES S P+ A+ TP+
Sbjct: 1582 WEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEA-TPV- 1639
Query: 1575 QRSRSGSSPEVDSKS--RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL 1632
+G SP + S+S +L S P++K A +G L
Sbjct: 1640 ----NGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAG--------------L 1681
Query: 1633 PRRSRSGSSSKGRGPS-PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSS 1691
+ GS S +GPS PE + PE P +S + RG + K R
Sbjct: 1682 EQTGPLGSRSTAKGPSLPE----LQFQPEEPEESEPS-RGQDPLTDQKQADSADKRPAEG 1736
Query: 1692 RSSPELTRKARLSRR---SRSASSSPETRSRTPPRHRRSPSVS--------SPEPAEKSR 1740
++ L + S R R +P S R RR ++ EP E
Sbjct: 1737 KAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGE--- 1793
Query: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800
SP TTS + K + S + + T D
Sbjct: 1794 -------PPSPSLTTTS----TSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDL--- 1839
Query: 1801 RQRSRSRSRVTR---RRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857
RS + VT +R G H++ S+ TS RR RK R ++
Sbjct: 1840 ----RSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIE----ALRKTVRPTSA 1891
Query: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917
P K S S A H S + PL R+ + +SR R + SP
Sbjct: 1892 PDVTKLSDSNKENALHSYSTQKGPL-KAGEQRAGSEVISRGGPRKADGQRQALDYVELSP 1950
Query: 1918 VSRRR-SRSRTPPVTRRRSRSRTPTTR---RRSRSRTPPVTRRRSRSRTPPVTRRRSRSR 1973
+++ R+RTP T R + R +RS R SR+ P R
Sbjct: 1951 LTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGL 2010
Query: 1974 TSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPA 2025
+P+T + + + ++ P+ + T+ + + R R PP+
Sbjct: 2011 GAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPS 2062
Score = 134 bits (337), Expect = 1e-30
Identities = 292/1303 (22%), Positives = 438/1303 (33%), Gaps = 228/1303 (17%)
Query: 1577 SRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS-------------------- 1616
S SG VD R P+R S S+ ++ P AAPR++S
Sbjct: 67 STSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSC 126
Query: 1617 ----GSDSSPEPKAPAPR----------------------------ALPRRSRSG--SSS 1642
GSD + P + P +PRR R G + S
Sbjct: 127 NEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADS 186
Query: 1643 KGRGP-----SPEGSSST-----------ESSPEHPPKSR------------TARRGS-- 1672
R P SP G + S+ +H + R T + S
Sbjct: 187 SQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSM 246
Query: 1673 --RSSPEPKTKSRTPPRR-----RSSRSSPELTRKARLSRRSRSASSSPETR----SRTP 1721
S P T +P +R S+R P + R+++R S +SS + S T
Sbjct: 247 TPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQ 306
Query: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSAS----SPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777
R+ S P S R++S +PR + SR + +P+ Q+ ++
Sbjct: 307 QETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQT 366
Query: 1778 -------RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR-RRGGSGYHSRSPARQE 1829
+RE RT + + S +R QR SR+ +R S S + A ++
Sbjct: 367 SFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRD 426
Query: 1830 SSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSR 1889
+ RTS +R + P+ R TS A R+ + + +R +R +R
Sbjct: 427 NPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDN 486
Query: 1890 SRTSPVSRRRSRSRTSVTRRRSRSRA----SPVSRRRSRSRTPPVTRRRSRSRTPTTRRR 1945
R S SR + T+ +R RA SP R RT R R+ +P R
Sbjct: 487 PRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAAR 546
Query: 1946 SRSRTPPVTRRRSR-SRT-PPVTRRRSRSRTSPITRRRSR-------SRTSPVTRRRSR- 1995
T R R SRT P R RTS R R +R +P T R
Sbjct: 547 DNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRD 606
Query: 1996 ----SRT-SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAI 2050
SRT SP R RTS R R+ +P ++ RT R R+ SP
Sbjct: 607 NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRT 666
Query: 2051 RRRSRSRT-------PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSR 2103
++ RT PR + R++ + P S + D R+++P T R
Sbjct: 667 IQQENPRTSCALRDNPRASSPSRTIQQENP-----RTSCAQRDDPRASSPNRTTQQENPR 721
Query: 2104 TPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPR 2163
T ++ R S +R P C +RT + + D P
Sbjct: 722 TSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTS 781
Query: 2164 IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL--- 2220
P+ P R L ++ T + P R S P S
Sbjct: 782 SPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKR 841
Query: 2221 -RTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAP 2279
P R + S N ++ + NL S +P + N +PR + +P
Sbjct: 842 DNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPS-SPHRSTQWN--NPRNS-SP 897
Query: 2280 SAVN-----LADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPA 2334
N + P PT + + + + + PT + P +S +P PA
Sbjct: 898 HRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTS-SPSRPA 956
Query: 2335 SANLVGPRSAHATAPVNIAGSRTAAALAP----ASLTSARMAPALSGANLTSPRVPLSAY 2390
+ P+S+ N+ T+++ P S TS+ + PA GA LTSP
Sbjct: 957 QHD--PPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPE------ 1008
Query: 2391 ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP 2450
+ PP R P A S R + P P +AP PP + P P
Sbjct: 1009 -----PSQPPCAVCIGHRDAPRASSPPRYL-QHDPFPFFPEPRAPESE--PPHHEPPYIP 1060
Query: 2451 VPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPP 2510
+ C+ + P A SS H P P +P + E
Sbjct: 1061 -------PAVCIGHRDAPRA--------------SSPPRHTQF--DPFPFLPDTSDAEHQ 1097
Query: 2511 ASTGAQQPSALAA---LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS--EG 2565
+ +P L A + R+SS + S +S+ S S DS E
Sbjct: 1098 CQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHEC 1157
Query: 2566 SSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS-- 2623
+P + + PS + P++A PEP+ + +S S + S+ S S
Sbjct: 1158 PHIPTPVCIGHRDAPSFSSPPRQA------PEPSLFFQDPPGTSMESLAPSTDSLHGSPV 1211
Query: 2624 -------SSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
+ +SS S + + SPSP G S PPGE R
Sbjct: 1212 LIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSG-------GSRGSAPPGETRHN 1264
Query: 2677 SPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGS 2719
R+ L D P RR QP P+ Q SS S
Sbjct: 1265 LEREEYTVLAD------LPPPRRLAQRQPGPQAQCSSGGRTHS 1301
Score = 124 bits (310), Expect = 2e-27
Identities = 357/1630 (21%), Positives = 559/1630 (34%), Gaps = 286/1630 (17%)
Query: 388 QEPVNPPSEASPTRD--RSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAP 445
QE +P P D R PP + L S+S S P PK P
Sbjct: 38 QELRSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDP----------GLRPGPKRGP 87
Query: 446 APGSHREISSSPTSKNRSHGRAKRDKSHSH--TPSRRMGRSRSPATAKRGRSRSRTPTKR 503
+P + PT+ RS R + T S + P + S TP
Sbjct: 88 SPSAGLP-EEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDT 146
Query: 504 GHSRS-----------RSPQW--------RRSRSAQRWGRS-RSPQRRGRSRSPQRPGWS 543
+S S +P W RR R R S R+P RS
Sbjct: 147 SNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQ 206
Query: 544 RSRNTQRRGRSRSAR----RGRS-----HSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594
+ +T GRS RG S RS T+ S + R + +PA+R +
Sbjct: 207 KKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDT 266
Query: 595 RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654
TR R+ +P R ++ R S T+ + R S ++ R+ ++ TP
Sbjct: 267 AQAASTREIPRASSPHRI----TQRDTSRASSTQQEISRASSTQQETSRASSTQEDTP-- 320
Query: 655 RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH 714
R S R ++ TP R S SRS T R+ S T + S R +
Sbjct: 321 RASSTQEDTPRASSTQWNTP-RASSPSRS-TQLDNPRTSS-TQQDNPQTSFPTCTPQREN 377
Query: 715 SRTP--QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
RTP Q+ SS R + S+ +P K SR SS + +PR+ R
Sbjct: 378 PRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNP--KASRTSSPNRATRDNPRTSCAQR 435
Query: 773 LSLRRS----LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSK 828
+ R S + +P + PR SR+ S P +R PR S + P ++
Sbjct: 436 DNPRASSPSRATRDNPTTSCAQRDNPRASRTSS--PNRATRDNPRTSCAQRDNP---RAS 490
Query: 829 TPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFES----SPDPELKSR 884
+PSR + + P PR +SP N + R SC + + P +R
Sbjct: 491 SPSRATRDN--PTTSCAQRDNPRASRTSSP--NRATRDNPRTSCAQRDNPRASSPNRAAR 546
Query: 885 TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR 944
SC+ PR ++ SP+R++ P+ S QR + +SSP+
Sbjct: 547 DNPTTSCAQRDNPRASRTS----SPNRATRDNPRT----SCAQRDNPRASSPN------- 591
Query: 945 TTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP 1004
R+ +P ++ R PR S + S + T+ P T Q + S + Q
Sbjct: 592 ----RATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDS 647
Query: 1005 PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS 1064
P S + P ++ ++ S +L ++S+P S+T
Sbjct: 648 PRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSP----------------SRTI 691
Query: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
TS + + SP+ ++ Q +P+ +R +P +R+ I++D
Sbjct: 692 QQENPRTSCAQRDDPRASSPN-RTTQQENPRTSCARRDNPRASSRNRT-IQRD------- 742
Query: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDS-NSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183
+P S Q D+ P S N + Q L T+ +++ T+SP R
Sbjct: 743 -------NPRTSCAQRDN---PRASSPNRTIQQENLRTSCTRQ------DNPRTSSPNR- 785
Query: 1184 KDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVE 1243
+D P +S +D LR R+ +P T Q + +P SS ++
Sbjct: 786 -------ATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQN-IPRSSSTQQ------ 831
Query: 1244 KSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMAS 1303
+ P L+ T + +R + Q +Q P ++
Sbjct: 832 --DNPKTSCTKR--DNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRST 887
Query: 1304 SWGGPHFSPEHK-----ELSNSPLRENSFGSPLEFRNSGPLGTEMN-TGFSSEVKEDLNG 1357
W P S H+ ++ PLR P R S P ++ + ++S G
Sbjct: 888 QWNNPRNSSPHRTNKDIPWASFPLRPTQSDGP---RTSSPSRSKQSEVPWASIALRPTQG 944
Query: 1358 --PFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPS 1415
P + D + S + ++ + + G S SSPV A P
Sbjct: 945 DRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPL 1004
Query: 1416 RERSSS---------------ASSPE---MKDGLPRTPSRRSRSGSSP------------ 1445
S ASSP D P P R+ P
Sbjct: 1005 TSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVC 1064
Query: 1446 -GLRDG--SGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS-------PEPKALPQTPRP 1495
G RD + +P RH+ P + D S +C S P P + P
Sbjct: 1065 IGHRDAPRASSPPRHTQFDPFPFLPD----TSDAEHQCQSPQHEPLQLPAPVCIGYRDAP 1120
Query: 1496 RSRSPSSPELNNKCLTPQRERSGSES------SVDQKTVARTPLGQRSRSGSSQELDVKP 1549
R+ SP L R+ +ES S+ + TP+ R S P
Sbjct: 1121 RASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPS--FSSPP 1178
Query: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609
+P+ P + ++ P S GS + P+V R
Sbjct: 1179 RQAPEPSLFFQDPPGTSMESLAPSTD-SLHGSPVLI----------------PQVCIGHR 1221
Query: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRS-GSSSKGRGPSPEGSSSTESSPEH------- 1661
APRA SSP P+ A S S GSS RG +P G + E
Sbjct: 1222 DAPRA-----SSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADL 1276
Query: 1662 PPKSRTARR--GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
PP R A+R G ++ ++ +P R R + RK S + + + E RS+
Sbjct: 1277 PPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRK---SEAAGAFQAQDEGRSQ 1333
Query: 1720 TPP-------RHRRSPSVS---SPEPAEKSRSSRRRRSAS----SPRTKTTSRRGRSPSP 1765
P R + SP+ S + PA+++ +RR ++ SP + R SP
Sbjct: 1334 QPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSP 1393
Query: 1766 KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825
P R+ +R+ + RT R + S Q+ R+ +G + RS
Sbjct: 1394 LP---PRTSARTPERELRTQRPLE---SGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSW 1447
Query: 1826 ARQESSR------TSSRRRRGRSRTPP-----TSRKRSRSRTSPAPWKRSRSRASPATHR 1874
+ QE G ++ P TSR+ S P W+ + P R
Sbjct: 1448 SSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHELP---R 1504
Query: 1875 RSRSRTPLIS 1884
R+PL S
Sbjct: 1505 ELGKRSPLTS 1514
Score = 108 bits (269), Expect = 9e-23
Identities = 262/1139 (23%), Positives = 404/1139 (35%), Gaps = 188/1139 (16%)
Query: 1574 RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ-------SGSDSSPEPKA 1626
+ R ++ PE +R RS SG+ D PR P + SG S +P
Sbjct: 20 QNRCQNCFHPEEAHGARYQELRSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGL 79
Query: 1627 -PAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP 1685
P P+ RGPSP + E P P+SR+ + E T S
Sbjct: 80 RPGPK--------------RGPSPS-AGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCG 124
Query: 1686 PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS--SPEPAEKSRSSR 1743
S P +SSP+ S TP S SV + E E+ S
Sbjct: 125 SCNEDPGSDP---------------TSSPD--SATPDDTSNSSSVDWDTVERQEEEAPSW 167
Query: 1744 RRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQR 1803
+ PR R S P L RS ++ D G +S + R
Sbjct: 168 DELAVMIPRRPREGPRADSSQRAPSLLTRSPVGG---DAAGQKKEDTGGGGRSAGQHWAR 224
Query: 1804 SRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKR 1863
R S ++ R RS Q SS T P + + + S+ SPA +R
Sbjct: 225 LRGESGLSLERH-------RSTLTQASSMT-----------PHSGPRSTTSQASPA--QR 264
Query: 1864 SRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923
++A+ +T R+ +P +R SR S S ++ SR S T++ + SRAS
Sbjct: 265 DTAQAA-STREIPRASSPHRITQRDTSRAS--STQQEISRASSTQQET-SRASSTQEDTP 320
Query: 1924 R-SRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT--------PPVTRRRSRSRT 1974
R S T T R S ++ T R S SR+ + R+ S P T +R RT
Sbjct: 321 RASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRT 380
Query: 1975 SPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR-SRTSPVTRR-RSRSRTPPAIRRRSRS 2032
+ + R+ + T +R SRTS R + SRTS R R RT A R R+
Sbjct: 381 PCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRA 440
Query: 2033 RTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092
+P + +R + +R R RT+ R+ +P S + D R+++
Sbjct: 441 SSP---SRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP------RTSCAQRDNPRASS 491
Query: 2093 PP-ATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSR-TPMSVLQ 2150
P ATR++ P+ S D R+ P ++R P +
Sbjct: 492 PSRATRDN--------------------PTTSCAQRDNPRASRTSSPNRATRDNPRTSCA 531
Query: 2151 QAGGSMMDGPGPRIPDHQRTSVPE--NHAQSRIALALTAISLGTARPPPSMSAAGLAARM 2208
Q P D+ TS + N SR T+ R P S A +
Sbjct: 532 QRDNPRASSPNRAARDNPTTSCAQRDNPRASR-----TSSPNRATRDNPRTSCA----QR 582
Query: 2209 SQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAM 2268
A P + R P + A R N ++RT ++ N A P + A
Sbjct: 583 DNPRASSPNRATRDNPTTSCAQRD--------NPRASRT----SSPNRATRDNPRTSCAQ 630
Query: 2269 NLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSR 2328
+PR A +P+ D +P + A P A + P T+ + R
Sbjct: 631 R-DNPR-ASSPNRTTQQD-----SPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPR 683
Query: 2329 TPQAPASANLVGPRSAHATA--PVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
+ PR++ A P + +RT P + + R P S N T
Sbjct: 684 ASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRT----- 738
Query: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQ-------SRMTSERAPSPSSRMGQAPSQSL 2439
+R + RTS D R+ +P Q +R + R SP+ P S
Sbjct: 739 ---IQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSC 795
Query: 2440 LPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATT-------TSSAGDHNG 2492
+ SP+ + D R I Q P + S + + T T + D
Sbjct: 796 AQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQ 855
Query: 2493 MLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS- 2551
S + P ++ +Q + L+P+ RS+ ++ +SS ++
Sbjct: 856 SFSFQR---------DNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPW 906
Query: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611
+S + SD +S P + + S P A+R PT R + SS S
Sbjct: 907 ASFPLRPTQSDGPRTSSPSRSK------QSEVPWASIALR------PTQGDRPQTSSPSR 954
Query: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA-SPKKPP 2669
+ SS + + S ++SSS + S+S + SP P P + P +PP
Sbjct: 955 PAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPP 1013
Score = 69.3 bits (168), Expect = 5e-11
Identities = 104/467 (22%), Positives = 176/467 (37%), Gaps = 52/467 (11%)
Query: 2325 SSSRTP----QAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANL 2380
SS R P ++P + G + AG A + L+ R L+ A+
Sbjct: 186 SSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASS 245
Query: 2381 TSPRVPLSAYERVSGRTSPPLLDRARS---RTPPSAPSQSRMT---SERAPSPSSRMGQA 2434
+P S + + SP D A++ R P A S R+T + RA S + +A
Sbjct: 246 MTPH---SGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRA 302
Query: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTT----PVAGSQSLSSGAVATTTSSAGDH 2490
S + P A S Q A +T P A S S S+ TSS
Sbjct: 303 SSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQD 362
Query: 2491 NGMLSVPA-------PGVPHSDVGEPPAS----TGAQQPSALAALQPAKERRSSSSSSSS 2539
N S P P P +P AS T ++ S + Q + S +SS +
Sbjct: 363 NPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNR 422
Query: 2540 SSSSSSSSSSSSSSSSSGSSSS----DSEGSSLPVQPEVALKRVPSPTPAPKEAVREG-- 2593
++ + +S + + SS S D+ +S + R SP A ++ R
Sbjct: 423 ATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCA 482
Query: 2594 ---RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
P +P++ R + ++S + + +S +SS + ++ + +S + + +SSP+
Sbjct: 483 QRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPN 542
Query: 2651 -PAKPGPQAL----PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705
A+ P P + + P +PR + R+ S + R P+
Sbjct: 543 RAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSC 602
Query: 2706 ----SPRDQQSSSSERGSRR------GQRGDSRSPSHKRRRETPSPR 2742
+PR ++SS R +R QR + R+ S R + SPR
Sbjct: 603 AQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPR 649
Score = 35.0 bits (79), Expect = 1.0
Identities = 32/149 (21%), Positives = 57/149 (38%), Gaps = 4/149 (2%)
Query: 391 VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH 450
++P ++ASP R R+P ++P++L + E + ++ +P+ G
Sbjct: 1948 LSPLTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPR 2007
Query: 451 REISSSPT--SKNR-SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR 507
R + + T +NR S K+ + P R R A + R R P GH
Sbjct: 2008 RGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEA 2067
Query: 508 SRSPQWRRSRSAQRWG-RSRSPQRRGRSR 535
+ W + +PQ RS+
Sbjct: 2068 LEKEVQALRAQLEAWRLQGEAPQSALRSQ 2096
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 167 bits (424), Expect = 1e-40
Identities = 421/2009 (20%), Positives = 697/2009 (34%), Gaps = 304/2009 (15%)
Query: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ--------GSITSPQA---NEQ 863
+++S P P + TP SS + GT P G SP A
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 864 SVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS--------- 914
+ P + SS L + P S + PP + +S PP + + S S
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTS-PPSVAVAESGSVITLSAPIA 180
Query: 915 -PQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRL--LPRYSHSG 971
+PK P + + +PSP + S T P V+P ++++S + LP+ + +
Sbjct: 181 PSEPKTNLNKVPSEVVPNPKGTPSPPCIVS-TVPYHC--VTPMASIQSGVASLPQTTPTT 237
Query: 972 S---SSPDTK--------VKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEK 1020
+ +SP K + P+ P S G +SP + T P ++ S+
Sbjct: 238 TLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNT 297
Query: 1021 SKD----------SLVQSCPGSLSLCA--GVKSSTPP------------GESYFGVSSLQ 1056
D L QS GS+ L G + + P G SY S+
Sbjct: 298 PPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357
Query: 1057 LKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGG----RSRSSSPVTELASRS 1112
S+ + + P V S + PS S SP G S S SP T L +S
Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417
Query: 1113 PIRQDRGE--FSASPMLKSGMSP------------EQSRFQSDSSSYPTVDSNSLLGQSR 1158
+ P+ G +P + F+ + P + S + S
Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPI---SN 474
Query: 1159 LETAESKEKMALP--PQEDAT---------ASPPRQKDKFSPFPVQDRPESSLVFKDT-- 1205
+E + P P+E +T SPP P +++ P S LV T
Sbjct: 475 IEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLP----DPEDLKNLPSSVLVKFPTQK 530
Query: 1206 -LRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMS 1264
L+T P GA SP A T+ +D ++ +V+ + + + S SS +S
Sbjct: 531 DLQTVPASLEGAPFSPA-----QAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLS 585
Query: 1265 TSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRE 1324
+ + E + S + + S+ GP S PL +
Sbjct: 586 PEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPD--------SAGPLLK 637
Query: 1325 NSFGSP----LEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG 1380
+S +P ++ P G T + PFL E SL K +
Sbjct: 638 SSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFL---EGTVSLAPKNHPVKEGT 694
Query: 1381 HSSSELSPDAVEKAGMS-SNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRS 1439
++ L P A E ++ S Q+ +P+ V +PE+ +P +PS
Sbjct: 695 LTTLPLVPTASENCPVAPSPQNTCAPLATLV------------LAPEIPKSVP-SPSLPP 741
Query: 1440 RSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRS 1499
+G+ PG + G +L+ + K+ P S + S L +P P S
Sbjct: 742 -AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVS 800
Query: 1500 PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSES 1559
S PQ +R ++ TP+G S S V+ S P+
Sbjct: 801 VS----------PQTKRPPTKKG---SAGPDTPIGNLSSPVSP----VEASFLPENSLSF 843
Query: 1560 DSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSD 1619
S DS A T +P + +P + + LSP+ G + K+ P P +
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPS--AVTPLSPK----GVTLPPKETP--TPSVVNLPF 895
Query: 1620 SSPEPKAPAPRALPRRSRSGSSSKGRG--PSPEG---SSSTESSPEHPPKSRTARRGSRS 1674
P PAP+ P S + SS K P+P+G S S + +P P + + +G +
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA 955
Query: 1675 SPEPK----TKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV 1730
+P PK + TPP + ++P S +P + TPP + P+
Sbjct: 956 TPSPKWAPTPPAATPPSPKGGPATP-------------SPKGAPTPPAATPPSPKGGPAT 1002
Query: 1731 SSPE----PAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTR 1786
SP+ P + S + A++P K S + P P+G + + T
Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062
Query: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP 1846
+T + + +GG S A + T + G + P
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122
Query: 1847 TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSV 1906
+ + T P+P K + P + + TP S + + P + + T
Sbjct: 1123 KGAPTTPAATPPSP-KGGLATPPPKGAPTTPAATPP-SPKGGLATPPPKGAPTTPAATPP 1180
Query: 1907 TRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP--- 1963
+ + + SP + + TPP + + +P + + TPP + + +P
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
Query: 1964 PVTRRRS--RSRTSPITRRRSRSRTSPVTRRRS----------RSRTSPVTRRRSRSRTS 2011
P T + + P T + T P S + +P +
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 2012 PVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRS 2071
P T + TPPA S +P P + P TP + +G +L +
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV--------TPPSPKGTPTLPAT 1352
Query: 2072 PPAIRRRSASGSSSDRSRSATPPA-TRNHSG--SRTPPVALNSSRMSCFSRPSMSPTPLD 2128
P+ + + SS + TPPA T +H G + TPP + R P PT
Sbjct: 1353 TPSSKGGPTTPSSKE---GPTPPAATPSHKGGPAMTPP---SPKRGPAIPSPKGDPT--- 1403
Query: 2129 RCRSPGMLEPLGSSRTPMSVLQQAGG---SMMDGPGPRIPDHQRTSVPENHA-------- 2177
SP ++ PL + P + + + G S D P + P A
Sbjct: 1404 ---SPAVI-PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
Query: 2178 QSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLAS--RIPAA 2235
S+ L A++ + + PP+ ++ + PA M T PA +S +PA
Sbjct: 1460 SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPAT 1519
Query: 2236 SAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPR-TPTAPA 2294
+ S R P PTA L +TPA A P+ A+ P A+ + P+ TP P
Sbjct: 1520 PS------SRRDPIAPTAT-LLSKKTPATLA------PKEALIPPAMTVPSPKKTPAIPT 1566
Query: 2295 VNLAGAR-------TPAALAALSLTGSGTP-----PTAANYPSSSRTPQAPASANLVGPR 2342
A A +P A+ + G+ +P P A PS P PA +
Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
Query: 2343 SAHATAPVNIAGSRTAAALAPASLTSARMAPAL-----------SGANLTSPRVPLSAYE 2391
AP G+ T+ + P+SL + +PA + L + + P + E
Sbjct: 1627 GPATPAP---KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKE 1683
Query: 2392 RVSGRT--SPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRS 2449
+ S P++ A +R P S + P PS++ G S + PA P
Sbjct: 1684 VLVAPAPESTPIIT-APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA---PLL 1739
Query: 2450 PVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
PV S ++ A +P S A T++A + +P P
Sbjct: 1740 PVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK----VLPKPESASVSAAPS 1795
Query: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG---- 2565
P + PS + L P ++ SS S S + + G
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855
Query: 2566 -SSLPVQPEVALKRVPSPTPAPKEAV--------REGRPPEPTPAKRKRRSSSSSSSSSS 2616
S L P +P PTP+ K+ V E E P ++ S+ +++ +
Sbjct: 1856 QSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ 1915
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
++++ S + S S + + S
Sbjct: 1916 LAAAAEIDEEPVSKAKQSRSEKKARKAMS 1944
Score = 130 bits (328), Expect = 1e-29
Identities = 442/2006 (22%), Positives = 708/2006 (35%), Gaps = 323/2006 (16%)
Query: 804 PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQ 863
P + P ++ ++ P S T + + P P P+Q +++ AN+
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPP---CSPAPQQCPLSA--ANQA 64
Query: 864 SVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSP-QPKVKAI 922
S P S S+P P S SG++ P + P P+ P P A+
Sbjct: 65 SPFPSP-STIASTP-----LEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL 118
Query: 923 ISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE 982
SP +P+ S + P +++P S +S P + +SP + E
Sbjct: 119 ASPM-------IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP---NLLTSPPSVAVAE 168
Query: 983 TPPRQSHSGSISPY-PKVKAQTPPG---PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAG 1038
+ + S I+P PK P P+ G+ SP +V + P
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP-------PCIVSTVP-------- 213
Query: 1039 VKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP--------SLQSKS 1090
TP GV+SL QT+P +SP+V+ + S SL K
Sbjct: 214 YHCVTPMASIQSGVASLP-----QTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKG 268
Query: 1091 QTSPKGGRSRS--SSPVTELASRSPIRQDRGEFSASPMLKSGMSP-EQSRFQSDSSSYPT 1147
SP S S S PV + ++ +F S L S ++P QS F
Sbjct: 269 PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPIS--LGSHLAPLHQSSF--------- 317
Query: 1148 VDSNSLLGQSRLETAESKEKMALPPQEDAT-ASPPRQKDKFSPFPVQDRPESSLVFKDTL 1206
S LLGQ+ + +T AS P Q+ P P ++ + V +
Sbjct: 318 -GSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPV 376
Query: 1207 RTPPRERSGAGSSPETKEQNSAL--PTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMS 1264
P ++ + S T + +L TS ++ KS A ++ + +M
Sbjct: 377 VAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNA----TYHYPLVAQMP 432
Query: 1265 TSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRE 1324
S+ ++P V P + A EV + S +S+ P+
Sbjct: 433 VSSVGTTPLVVTNPCTI-------AAAPTTTFEVATCVSP-----------PMSSGPISN 474
Query: 1325 NSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF-----LNQLETDPSLDMKEQSTRSS 1379
SP + E +T ++ ++ ++ P L L + + Q +
Sbjct: 475 IEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQT 534
Query: 1380 GHSSSELSPDAVEKAGMSSNQSISS-PVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438
+S E +P + +AG+++ + + P++ A P+ S S++SSPE+ T +++
Sbjct: 535 VPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKN-SPSFQSTSSSPEIPLSPEATLAKK 593
Query: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMK-DIPRTPSRGRSECDSS---PEPKALP-QTP 1493
S P + S S ++ S+ +K D P SS P A P ++
Sbjct: 594 SLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESA 653
Query: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553
P +P++ + + T + S + TV+ P + G+ L + P+AS
Sbjct: 654 DPAGVAPTTAKGTSTYTT-------TASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTAS- 705
Query: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
E+ S T PL + +PE+ KS SP +G+ P K +
Sbjct: 706 ----ENCPVAPSPQNTCAPL---ATLVLAPEIP-KSVPSPSLPPAGTPPGTKKVDGIS-- 755
Query: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGS---SSKGR------GPSPEGSSSTESSPEHPPK 1664
S+ P A +P+ P S SSKG PSP G S + + P K
Sbjct: 756 ----HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
Query: 1665 SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724
+A P+ TP SS SP + L S S S ++ + T
Sbjct: 812 KGSA------GPD------TPIGNLSSPVSP--VEASFLPENSLSFQGSKDSPATT---- 853
Query: 1725 RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRT 1784
SP+ SP K + + SP+ T + +P+P L + E T
Sbjct: 854 -HSPTPPSP----KGAPTPSAVTPLSPKGVTLPPK-ETPTPSVVNLPFPK-----EGPAT 902
Query: 1785 TRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRT 1844
+ S ++S S ++R T +G S A + T + G +
Sbjct: 903 PAPKQAPALSMTSS-----SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957
Query: 1845 PPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT 1904
P + T P+P + PAT + TP + T
Sbjct: 958 SPKWAPTPPAATPPSP------KGGPATPSPKGAPTP-------------------PAAT 992
Query: 1905 SVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPP 1964
+ + + SP + TPP + + S + TP + S TPP S +P
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPP-SPKGSPAATPFPKGAS---TPPAATPPSPKGSPA 1048
Query: 1965 VTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPP 2024
T + T+P S + P T + T P S + P T + PP
Sbjct: 1049 ATPLPKGAPTTPAATLPS-PKGGPATPSLKGAPTPPAATPPS-PKGGPATPSPKGAPMPP 1106
Query: 2025 AIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS 2084
A S P + +P A TP + +G + T P A+
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAA--------TPPSPKGGLA-TPPPKGAPTTPAATPP 1157
Query: 2085 SDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRT 2144
S + ATPP G+ T P A S + PS P +P P G T
Sbjct: 1158 SPKGGLATPPP----KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP--SPKGGLAT 1211
Query: 2145 PMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGL 2204
P G P P + A + A + G A PPP +
Sbjct: 1212 P----SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 2205 AARMSQVPAPVPLMSLRTAP-AANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPA 2263
AA + + + AP A + P A A TP T P+
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP--------PS 1319
Query: 2264 AAAAMNLASPRTAVAPSAVNLADPR-TPTAPAVNLA------------GARTPAALAALS 2310
+ P+ A P AV P+ TPT PA + G PAA +
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379
Query: 2311 LTGSGTPPTAAN---YPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAA--LAPAS 2365
+ TPP+ PS P +PA L P+ A AT PV G+ T + L P +
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL-SPKKAPAT-PVTREGAATPSKGDLTPPA 1437
Query: 2366 LT--SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTS-- 2421
+T S + APA S A P P S + +PP S P AP Q +S
Sbjct: 1438 VTPVSLKKAPATS-APKGGPATPSSKGDPTLPAVTPP------SPKEPPAPKQVATSSSP 1490
Query: 2422 ERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA 2481
++AP+ + MG AP+ + P+ + PS+ D P+A + +L S
Sbjct: 1491 KKAPATPAPMG-APTLPAVIPSSPKEVPATPSSRRD----------PIAPTATLLSKKTP 1539
Query: 2482 TTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541
T + + PPA T P A+ KE ++ SS +SS
Sbjct: 1540 ATLAP-----------------KEALIPPAMT-VPSPKKTPAIPTPKEAPATPSSKEASS 1581
Query: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTP- 2600
+ + S+ + S L + P V +P+PKEA PP TP
Sbjct: 1582 PPAVTPSTYKGAPSP---------KELLIPPAVT-------SPSPKEAPT---PPAVTPP 1622
Query: 2601 AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL- 2659
+ K ++ + + +S + SS S +S +S + ++ +S PAK GP AL
Sbjct: 1623 SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALK 1682
Query: 2660 -----PKPAS------PKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP-QPSP 2707
P P S P + P ++S + PI +++ S P+ P+P P
Sbjct: 1683 EVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742
Query: 2708 RDQQSSSSERGSRRGQRGDSRSPSHK 2733
+D ++ + + +G P K
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESK 1768
Score = 128 bits (322), Expect = 7e-29
Identities = 420/2001 (20%), Positives = 679/2001 (33%), Gaps = 341/2001 (17%)
Query: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL 773
H TP +SG +S +T+ + + +SP++K + ISS L SP++
Sbjct: 215 HCVTPMASIQSGVAS----LPQTTPTTTLAIASPQVKDTTISS----VLISPQNPGSL-- 264
Query: 774 SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP-PPKQKSKTPSR 832
SL G P S + SSQ A TPP S S P +S S
Sbjct: 265 ----SLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSV 320
Query: 833 QSHSSSSPH----PKVKS---------GTPPRQGSITSPQANEQSVTPQRRSCFES-SPD 878
Q + P P VK+ + P Q S+ P + V P + F +P
Sbjct: 321 QLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPS 380
Query: 879 PELKSRTPSRHSCSGSSPPRVKSS--TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP 936
+ T S +CS S V +S P S SSP + + S ++P
Sbjct: 381 VDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTP 440
Query: 937 S--PSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSIS 994
+ T P + V+ C S SS P + ++P +P +
Sbjct: 441 LVVTNPCTIAAAPTTTFEVATC----------VSPPMSSGPISNIEPTSPAALVMAPVAP 490
Query: 995 PYPKVKAQT-------PPGPSLSGSKS-------PCPQEKSKDSLVQSCPGSLSLCAGVK 1040
P + T PP P K+ P +K ++ S G+ A
Sbjct: 491 KEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
Query: 1041 SSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSR 1100
+T + + ++ + SP +S +SSPE+ S + + +S + P G +
Sbjct: 551 LTTKKDPTVLPL----VQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPAS 606
Query: 1101 S-SSPVTELASRSPIRQDR--GEFSASPMLKSGM-SPEQSRFQSDSSSYPTVDSNSLLGQ 1156
S +SP+ +S S I+ D G SA P+LKS + +P + F +S+ V + G
Sbjct: 607 SMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGT 666
Query: 1157 SRLETAES---KEKMALPPQ-----EDATASPPRQKDKFSPFPVQDRPESSLVFKDTL-- 1206
S T S + ++L P+ E + P PV P+++ TL
Sbjct: 667 STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726
Query: 1207 ------RTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQ--------I 1252
P AG+ P TK+ + TS+ E E +G
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
Query: 1253 LSHLSSELKEMSTSNFESSPEVEERPAVSLTL-------DQSQSQASLEAVEVPSMASSW 1305
L++L+ + S SP+ + P + + S + +EA +P + S+
Sbjct: 787 LTYLADSPSPLGVS---VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843
Query: 1306 GGPHFSPEHKELSNSPLRENSFGSPLEFR-------------NSGPLGTEMNTGFSSEVK 1352
G SP ++SP + G+P P + +N F E
Sbjct: 844 QGSKDSPA---TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKE-- 898
Query: 1353 EDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELS-PDAVEKAGMSSNQSISSPVLDAVP 1411
GP + P+L M S + + + + P + G + + + P P
Sbjct: 899 ----GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954
Query: 1412 RTPSRERSSS--ASSPEMKDGLPRTPSRRSR----SGSSPGLRDGSGTPSRHSLSG---- 1461
TPS + + + A++P G P TPS + + + P + G TPS
Sbjct: 955 ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014
Query: 1462 ------SSPGMKDIPR--------TPSRGRSECDSSPEPKALPQTPR------------- 1494
SP P+ TP + ++P PK P TP
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074
Query: 1495 -------PRSRSPSSPELNNKCLTPQ----------RERSGSESSVDQKTVARTPLGQRS 1537
P + +P SP+ +P+ G ++ K TP
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP-AATP 1133
Query: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR 1597
S P +P + + SP T P +P + + SP+
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP-------KGAPTTPAATPPSPKGGL 1186
Query: 1598 SGSSPE-VKDKPRAAPRAQSGSDSSPEPK-AP-APRALPRRSRSGSSSKGRGPSPEGSSS 1654
+ SP+ P A P + G ++P PK AP P A P + G ++ PSP+G+ +
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT----PSPKGAPT 1242
Query: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
T ++ PK A + +P P + TPP + ++P +P
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTP--PAATPPSLKGGLATP-------------PHKGAP 1287
Query: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPS---PKPRGLQ 1771
TPP + P+ S P+ A ++ SP T P+ P P+G
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG-- 1345
Query: 1772 RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831
T T S T+ + + T +GG SP
Sbjct: 1346 ----------TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP------ 1389
Query: 1832 RTSSRRRRGRSRTPPTSRKRSRSRTSPA--PWKRSRSRASPATHRRSRSRTPLISRRRSR 1889
+RG + P TSPA P ++ A+P T R + TP +
Sbjct: 1390 ------KRGPAIPSPKG-----DPTSPAVIPLSPKKAPATPVT--REGAATP-SKGDLTP 1435
Query: 1890 SRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSR 1949
+PVS +++ + S + P + T P S P ++ + S
Sbjct: 1436 PAVTPVSLKKAPA-------TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488
Query: 1950 TPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR 2009
+P + P T + T P S + P T R +P S+
Sbjct: 1489 SP---------KKAPATPAPMGAPTLPAV-IPSSPKEVPATPSSRRDPIAPTATLLSKK- 1537
Query: 2010 TSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRS-RSRTPRTARGKRSL 2068
+P T + PPA+ S +TP +P + +P + S + TP T +G S
Sbjct: 1538 -TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596
Query: 2069 TR--SPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTP 2126
PPA+ S S + + TPP+ + P S ++ S +P
Sbjct: 1597 KELLIPPAV--TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654
Query: 2127 LDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALT 2186
G P S P A ++ P P S P A +R T
Sbjct: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE-------STPIITAPTRKG-PQT 1706
Query: 2187 AISLGTARP--PPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLAS 2244
S T+ P P + G +S V AP PL+ ++ +S A +
Sbjct: 1707 KKSSATSPPICPDPSAKNGSKGPLSTV-APAPLLPVQ-----------KDSSKTAKGKDA 1754
Query: 2245 ARTPAIPTAVNLADSRTPAAAAAMN--LASPRTA-------------VAPSAVNLADPR- 2288
+ +P P A + + TP AAA L P +A +APS V P+
Sbjct: 1755 SHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQ 1814
Query: 2289 --TPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA 2346
P++P + L P A A PP P S P N+ P+SA
Sbjct: 1815 QFLPSSPGLVLESPSKPLAPADEDELLPLIPPE----PISGGVPFQSVLVNMPTPKSAGI 1870
Query: 2347 TAPV---------NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRT 2397
P N GS T + S P L + T + +
Sbjct: 1871 PVPTPSAKQPVTKNNKGSGTES-------DSDESVPELEEQDSTQATTQQAQLAAAAEID 1923
Query: 2398 SPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLL-----PPAQDQPRSPVP 2452
P+ +SR+ A R + +R+ S+++L P P S
Sbjct: 1924 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY 1983
Query: 2453 SAF--------SDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
F S Q++ A+ V G +++S+ T T + + + V GV
Sbjct: 1984 IVFGEAKIEDLSQQAQLAAAEKFKVQG-EAVSNIQENTQTPTVQEESEEEEVDETGVEVK 2042
Query: 2505 DVGEPPASTGAQQPSALAALQ 2525
D+ + + A+ AL+
Sbjct: 2043 DIELVMSQANVSRAKAVRALK 2063
Score = 115 bits (289), Expect = 5e-25
Identities = 267/1249 (21%), Positives = 442/1249 (35%), Gaps = 162/1249 (12%)
Query: 164 APEPPKPYSLVRESSSSRSPTPKQKKKKK--KKDRGRRSESSSPRRERKKSSKKKKHRSE 221
APE PK V S + TP KK +SSP+ + S S
Sbjct: 727 APEIPKS---VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783
Query: 222 SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS-----DTSR 276
+ SP+P S KR ++ + P + + S+ +S S
Sbjct: 784 KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843
Query: 277 SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP---SS 333
S+ + A TH+ PSP P S G T + + + P
Sbjct: 844 QGSKDSPATTHSPT----PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899
Query: 334 PYEDKDKDKKEKSATRPSPSPERSSTGPE--PPAPTPLLAERHGGSPQPLATTPLSQE-- 389
P K S T SP R++ P+ P +P+P G+P P A TP S +
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPK------GAPTPPAATPPSPKGG 953
Query: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
P P + +PT + P SP+ P + S + +P P T S + SPK AP P +
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 450 HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR-SPATAKRGRSRSRTPTKRGHSRS 508
+P S S K S P+ + SPA + TP S
Sbjct: 1014 -----VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
Query: 509 RSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW----SRSRNTQRRGRSRSARRGRSHS 564
P + A + P +G +P G + + + + G + +G +
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 565 RS---PATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS---R 618
+ P+ +G + P + + TP + TP + + + TPA S
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT-TPAATPPSPKGGLA 1187
Query: 619 TPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS---RTPARRGRSRSRTPA 675
TP+ + + T S A S + TPA S TP+ +G +
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1247
Query: 676 RRSGRSRSRTPARRGRSR--SRTPRRGRSRSRSLVRRGRSHSRT---PQRRGRSGSSSER 730
S + TP +G + TP + + +G + P +G +S +
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307
Query: 731 KNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL-SLRRSLSGSSPCPKQK 789
+ + SP + + +++ P K L + S G P K
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPK-GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366
Query: 790 S-QTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS--RQSHSSSSPHPKVKS 846
TPP + S P + TPP R + P PK +P+ S + P +
Sbjct: 1367 EGPTPPAATPSHKGGP---AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
Query: 847 GTP-PRQGSITSPQANEQSV-------TPQRRSCFESSP-DPELKSRTPSRHSCSGSSPP 897
G P +G +T P S+ P+ SS DP L + TP +P
Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPK-EPPAPK 1482
Query: 898 RVKSSTPPRQSPSRSSSP-QPKVKAII--SPRQRSHSGSSSPSP--------SRVTSRTT 946
+V +S+ P+++P+ + P + A+I SP++ + SS P S+ T T
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542
Query: 947 PRRSRSVSPCSNVESRL------LPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY---- 996
+ + P V S P+ + + SS + P P ++ G+ SP
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP-STYKGAPSPKELLI 1601
Query: 997 ------------PKVKAQTPPGPSLSGSKSPCPQ----------EKSKDSLVQSCPGSLS 1034
P A TPP P G +P P+ KDS +
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPE-KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Query: 1035 LCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSP 1094
+ A V ++ + G ++L+ + +P + S+P + + P + S TSP
Sbjct: 1661 MGATVPQASKGLPAKKGPTALK---EVLVAP---APESTPIITAPTRKGPQTKKSSATSP 1714
Query: 1095 K-----GGRSRSSSPVTELASRS--PIRQDRGEFS----ASPMLKSGMSPEQSRFQSDSS 1143
++ S P++ +A P+++D + + AS K ++P +S+ + +
Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774
Query: 1144 SYPTVDSNSLLGQSRLETAESKEKMALP--PQEDATASPPRQKDKFSPFPVQDRPESSLV 1201
+ + +S +A ++LP P T P +Q SP V + P L
Sbjct: 1775 A-AAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833
Query: 1202 FKDTLRT----PPRERSGAG-------SSPETKEQNSALPTSSQDEELMEVVEKSEEPAG 1250
D PP SG + P K +PT S + V K+ + +G
Sbjct: 1834 PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP----VTKNNKGSG 1889
Query: 1251 QILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299
+ + ES PE+EE+ + T Q+Q A+ E E P
Sbjct: 1890 T------------ESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEP 1926
Score = 115 bits (287), Expect = 8e-25
Identities = 306/1399 (21%), Positives = 486/1399 (34%), Gaps = 286/1399 (20%)
Query: 260 AHRSTSADSASSSD---TSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE--PG 314
+H S A ASS T S + + A+ T SPSP G +P ++ P
Sbjct: 755 SHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL----GVSVSPQTKRPPT 810
Query: 315 TTSTQRPSSPETATKQPSSPYEDKD--------KDKKEKSATRPSPSPERSSTGPEPPAP 366
+ P +P P SP E + K+ AT SP+P P P A
Sbjct: 811 KKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV 870
Query: 367 TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQ 426
TPL + P+ T + P A+P +P++ P S + SSP +
Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP--------APKQAPALSMTSSSPKKAR 922
Query: 427 PTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRS 486
T + +SP SPK AP P +++P S K TPS + +
Sbjct: 923 ATPAPKGIPASP-SPKGAPTPP-----AATPPS----------PKGGPATPSPKWAPTPP 966
Query: 487 PATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSR 546
AT + TP+ +G +P + G +P +G P
Sbjct: 967 AATPPSPKGGPATPSPKG-----APTPPAATPPSPKGGPATPSPKGAPTPP--------- 1012
Query: 547 NTQRRGRSRSARRGRSHSRSPATR--GRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRS 604
A S SPA + S PA S +PA PT +
Sbjct: 1013 ----------AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062
Query: 605 RSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS---R 661
+P + TP+ + + T S PA S + PA S
Sbjct: 1063 TLPSP----KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA 1118
Query: 662 TPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRR 721
TP +G TPA + P+ +G + P+ + + + TP +
Sbjct: 1119 TPPHKG--APTTPA-------ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG 781
G + + ++P K +++ + +P + A + S + L
Sbjct: 1170 GAPTTPA----------------ATPPSPKGGLATPSPK--GAPTTPAATPPSPKGGL-- 1209
Query: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH 841
++P PK TP + TPP ++P PK TP +++ P
Sbjct: 1210 ATPSPKGAPTTP--------------AATPPSPKGGLATPSPKGAPTTP-----AATPPS 1250
Query: 842 PKVKSGTPPRQGSITSPQANEQSV-----TPQRRSCFESSPDPELKSRTPSRHSCSGSSP 896
PK TPP +G+ T P A S+ TP + +P+P + + PS +SP
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK----GAPNPAVVT-PPSPKGGPATSP 1305
Query: 897 PRVKSSTPPRQSPSRSSSP-------QPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949
P+ + P PS SP P A+ P + + +PS TTP
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365
Query: 950 SRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSL 1009
+P +++P K P P G P PK +P L
Sbjct: 1366 KEGPTP---------------PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410
Query: 1010 SGSKSPC-------PQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQ 1062
S K+P SK L +SL +S P G
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG--------------GP 1456
Query: 1063 TSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFS 1122
+P + D + P V + P + T SSSP A+ +P+ G +
Sbjct: 1457 ATPSSKGDPTLPAVTPPSPKEPPAPKQVAT--------SSSPKKAPATPAPM----GAPT 1504
Query: 1123 ASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKM-------------- 1168
++ S SP++ S P + +LL + T KE +
Sbjct: 1505 LPAVIPS--SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562
Query: 1169 ALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNS- 1227
A+P ++A A+ P K+ SP V L PP A +SP KE +
Sbjct: 1563 AIPTPKEAPAT-PSSKEASSPPAVTPSTYKGAPSPKELLIPP-----AVTSPSPKEAPTP 1616
Query: 1228 -ALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER-PAVSLTLD 1285
A+ S ++ K + + S LK+ TS + ++ P S L
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPV---TPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673
Query: 1286 QSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNT 1345
+ +L+ V V +PE + +P R+ P ++S T
Sbjct: 1674 AKKGPTALKEVLVAP----------APESTPIITAPTRK----GPQTKKSS---ATSPPI 1716
Query: 1346 GFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP 1405
K GP L+ + P L +++ S++++ + SP K ++ +S +S
Sbjct: 1717 CPDPSAKNGSKGP-LSTVAPAPLLPVQKDSSKTAKGKDASHSP----KGPLAPPESKAST 1771
Query: 1406 VLDAV---PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGS 1462
L A P E +S +++P LP PS P L P + S
Sbjct: 1772 PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS------PVPTL------PPKQQFLPS 1819
Query: 1463 SPGMKDIPRTPSRGRSECDSS-------PEP--------KALPQTPRPRSRSPSSPELNN 1507
SPG+ + +PS+ + D PEP L P P+S P +
Sbjct: 1820 SPGL--VLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSA 1877
Query: 1508 K-CLTPQRERSGSESSVDQ---------KTVARTPLGQRSRSGSSQELDVKP-SASPQER 1556
K +T + SG+ES D+ T A T Q+++ ++ E+D +P S + Q R
Sbjct: 1878 KQPVTKNNKGSGTESDSDESVPELEEQDSTQATT---QQAQLAAAAEIDEEPVSKAKQSR 1934
Query: 1557 SESDSSPDSKAKTRTPLRQ 1575
SE + KA ++ LRQ
Sbjct: 1935 SEKKA---RKAMSKLGLRQ 1950
Score = 96.3 bits (238), Expect = 4e-19
Identities = 147/621 (23%), Positives = 233/621 (37%), Gaps = 77/621 (12%)
Query: 2187 AISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASAR 2246
++S T RPP +AG + + +PV + P +L+ + S A + +
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH---SP 856
Query: 2247 TPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPR----TPT---APAVNLAG 2299
TP P + TP + + L P+ PS VNL P+ TP APA+++
Sbjct: 857 TPPSPKGAPTPSAVTPLSPKGVTLP-PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915
Query: 2300 AR------TPAAL---AALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPV 2350
+ TPA A+ S G+ TPP AA PS P P+ P +A +P
Sbjct: 916 SSPKKARATPAPKGIPASPSPKGAPTPP-AATPPSPKGGPATPSPKWAPTPPAATPPSPK 974
Query: 2351 ------NIAGSRTAAALAPASLTSARMAPALSGANLT------SPRVPLSAYERVSGRTS 2398
+ G+ T A P S P+ GA SP+ +A G ++
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
Query: 2399 PPLLDRARSRTPPSAPS--QSRMTSERAPSPSSRMGQA-PSQSLLP-PAQDQPRSPV--P 2452
PP + P+A + T+ A PS + G A PS P P P SP P
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 2453 SAFSDQSRCLIAQTTPVAGSQSLSS----GAVATTTSSAGDHNGMLSVPAP-GVPHSDVG 2507
+ S + + TP + L++ GA T ++ G L+ P P G P +
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154
Query: 2508 EPPASTG--AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
PP+ G A P A PA S ++ S + ++ +++ S +
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214
Query: 2566 SSLPVQPEVALKRVPSP-----TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620
P P PSP TP+PK G P P + ++ + +
Sbjct: 1215 KGAPTTPAAT---PPSPKGGLATPSPK-----GAPTTPAATPPSPKGGPATPPPKGAPTP 1266
Query: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP---PPGERRSRS 2677
+++ S ++ + + + + PSP K GP P +P P PP + S
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSP-KGGPATSPPKGAPTPPAATPPSPKGSPG 1325
Query: 2678 PRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERG------SRRGQRGDSRSPS 2731
P + +P PSP+ +P ++ S +G S+ G + +PS
Sbjct: 1326 TPPPKGAP--------TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377
Query: 2732 HKRRRETPSPRPMRHRSSRSP 2752
HK P P R + SP
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSP 1398
Score = 86.3 bits (212), Expect = 4e-16
Identities = 131/583 (22%), Positives = 216/583 (37%), Gaps = 62/583 (10%)
Query: 2201 AAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSR 2260
+AG + S + V L +A A +A P + + +P + V+LA
Sbjct: 631 SAGPLLKSSLITPTVAAFPLESADPAGVA---PTTAKGTSTYTTTASPFLEGTVSLAPKN 687
Query: 2261 TPAAAAAMNL------ASPRTAVAPSAVNLADPRTPTAPAVNLAGA-RTPAALAALSLTG 2313
P + AS VAPS P+ AP L A P ++ + SL
Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPS------PQNTCAPLATLVLAPEIPKSVPSPSLPP 741
Query: 2314 SGTPPTAANYPSSSRTPQ-AP--ASANLVGPRSAHATAPVNIAGSRTAAALAPASL---- 2366
+GTPP S T AP +S + A+A + G+ T A +P+ L
Sbjct: 742 AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSV 801
Query: 2367 -TSARMAPALSGA--------NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS 2417
+ P G+ NL+SP P+ A S L + +P + S +
Sbjct: 802 SPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA----SFLPENSLSFQGSKDSPATTHSPT 857
Query: 2418 RMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSS 2477
+ + AP+PS+ +P LPP + S V F + A A S + SS
Sbjct: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS 917
Query: 2478 GAVATTTSSAGDHNGMLSVPAP-GVPHSDVGEPPASTG--AQQPSALAALQPAKERRSSS 2534
A T + G+ + P+P G P PP+ G A A PA S
Sbjct: 918 PKKARATPAP---KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974
Query: 2535 SSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV---ALKRVPSPTPAPKEAVR 2591
++ S + + +++ S + P P V + K P+ TP PK A
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA-- 1032
Query: 2592 EGRPPEPTPAKRKRRSSSS---SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
PP TP K +++ + ++ +++ S ++ S + + +++ S
Sbjct: 1033 -STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091
Query: 2649 PSPAKPGPQALPKPASPKKPPPGERRSRSPRK-----PIDSLRDSRSLSYSPVERRRP-- 2701
PA P P+ P P + P P + P K P + + +P + P
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151
Query: 2702 --SPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
+ PSP+ ++ +G+ + PS K TPSP+
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPA--ATPPSPKGGLATPSPK 1192
Score = 60.8 bits (146), Expect = 2e-08
Identities = 124/485 (25%), Positives = 187/485 (38%), Gaps = 86/485 (17%)
Query: 2215 VPLMSLRTAPAANLASRIPAASAAAMNLASART---------PAIPTAVNLADSRTPAAA 2265
+P + T PA P A A + ++SA + P +P + A + P +A
Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
Query: 2266 AAMNLASP---RTAVAPSAVNLADPRTPTAPAVNLAGART-----------PAALAALSL 2311
A N ASP + +A + + + P++ + A+ L A P + AAL+L
Sbjct: 61 A--NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL 118
Query: 2312 TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATA--PVNIAGSRTAAALAPASLT-- 2367
PT PSSS AP + + P S ++ P N+ S + A+A +
Sbjct: 119 ASPMIAPTLKGTPSSS----APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVIT 174
Query: 2368 -SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP-----PSAPSQSRMTS 2421
SA +AP+ NL +VP G SPP + S P P A QS + S
Sbjct: 175 LSAPIAPSEPKTNLN--KVPSEVVPNPKGTPSPPCIV---STVPYHCVTPMASIQSGVAS 229
Query: 2422 ERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVA--GSQSLSSGA 2479
+P++ + A P +D S V S Q+ ++ PV+ + SLS+ +
Sbjct: 230 LPQTTPTTTLAIAS-----PQVKDTTISSV--LISPQNPGSLSLKGPVSPPAALSLSTQS 282
Query: 2480 VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSS 2539
+ TSS P P + P S G S LA L SS S
Sbjct: 283 LPVVTSSQ-------KTAGPNTPP----DFPISLG----SHLAPLH------QSSFGSVQ 321
Query: 2540 SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT 2599
+ S+ S + + S S G+S P Q V +P P P+ E V P
Sbjct: 322 LLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSV----IP-PLPSRNEVVPATVAAFPV 376
Query: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL 2659
A S S+ SS + S S S + ++S S S ++S SSP+ P
Sbjct: 377 VAP-------SVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVA 429
Query: 2660 PKPAS 2664
P S
Sbjct: 430 QMPVS 434
Score = 33.5 bits (75), Expect = 3.0
Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 183 PTPKQKKKKKKKDRGRRSESSS----PRRERKKSSKKKKHRSESESKKRKHRSPTPKSKR 238
PTP K+ K ++G +ES S P E + S++ +++ + P K+K+
Sbjct: 1873 PTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQ 1932
Query: 239 KSKDKKRKRSRS 250
+KK +++ S
Sbjct: 1933 SRSEKKARKAMS 1944
Score = 32.7 bits (73), Expect = 5.1
Identities = 38/159 (23%), Positives = 55/159 (34%), Gaps = 15/159 (9%)
Query: 308 APFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPT 367
+P G S P+SP P +P E + P P+ PE
Sbjct: 464 SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPD-----PEDLKNL 518
Query: 368 PLLAERHGGSPQPLATTPLSQEPVN-PPSEASPTRDRSP---------PKSPEKLPQSSS 417
P + + L T P S E P++A T + P PK+ +SS
Sbjct: 519 PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSS 578
Query: 418 SESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS 456
S P SP+ T + KPA + S ++SS
Sbjct: 579 SPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSS 617
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 162 bits (410), Expect = 4e-39
Identities = 166/534 (31%), Positives = 231/534 (43%), Gaps = 75/534 (14%)
Query: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSS----PRRERKKSSKKKKHRSESESKK 226
+S + + P+ + KKKKKK R +R SSS P +++KK S KK R S SKK
Sbjct: 92 HSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKK 151
Query: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH----RSTSADSASSSDTSRSRSRS- 281
R+H S +PKSKR+ + + +K+SRS R H RS S++S SS SR R RS
Sbjct: 152 RRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSP 211
Query: 282 ----------------AAAKTHTTALAGRSPS---------------PASGRRGEGDAPF 310
K A + R PS SG +
Sbjct: 212 EEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKT 271
Query: 311 SEPGTTSTQR----------PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
+ P TTS R S P T T S ++K S +R S S +G
Sbjct: 272 ASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSG 331
Query: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEP---VNPPSEASPTRDRS-PPKSPEKLPQSS 416
+P + G + L+ T +E +P E + + S P + P
Sbjct: 332 NSFTTSSP---QNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKG 388
Query: 417 SSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT 476
S SS S T+ S H+S SP +P+ +P R SS S +RS + + S
Sbjct: 389 CSRSS--SYASTRSSSHSSRSP-NPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRS-P 444
Query: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRS 536
PSR RSP+ ++ SR R P +S S Q R R A+R RS SP R+ R S
Sbjct: 445 PSRSSRSRRSPSYSRYSPSRERDPK---YSEKDSQQRERER-ARRRRRSYSPMRKRRRDS 500
Query: 537 PQRPGWSRSRNTQRR-------GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTP 589
P R + ++R S S + S ++ RS SR+ RSRSR+
Sbjct: 501 PSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRS---YSRSRSRSR 557
Query: 590 ARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARR 643
+RRRSR+RT + SRS +P R RSRSR+ +R RSR++S + S S RR
Sbjct: 558 SRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
Score = 135 bits (340), Expect = 6e-31
Identities = 173/618 (27%), Positives = 263/618 (42%), Gaps = 81/618 (13%)
Query: 1475 RGRSECDSSPEPKAL------PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528
RG + ++P P+++ + P PR+ ++P + P ++ G + Q +
Sbjct: 17 RGTFKAVATPRPESIIVASITARKPLPRTEPQNNP------VVPAQD--GPSEKLGQH-L 67
Query: 1529 ARTPLGQRS--RSGSSQELDVKPSASPQERSESDSSPDSKAKTR----TPLRQRSRSGSS 1582
A PLG S R + +EL S + P S+ K + T ++R S S
Sbjct: 68 ATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYS 127
Query: 1583 PEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSS 1642
P SP + + S + + R+ + + S SSP+ K + ++SRS
Sbjct: 128 P--------SPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRK 179
Query: 1643 KGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKAR 1702
R S ++SS P + RG SPE KSR RR S R S L + +
Sbjct: 180 SHRHRHHRCPSRSQSSESRPSSCESRHRGR--SPEEGQKSR---RRHSRRCSKTLCKDSP 234
Query: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS----SRRRR--------SASS 1750
++ SR S + R + S S+ + K+ S SR R ++S
Sbjct: 235 EAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSP 294
Query: 1751 PRTKTTSRRGRSPSP-KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809
P T+T+S R R P G S+SR + T SG+S +TS + +
Sbjct: 295 PSTQTSSARSRGQEKGSPSG---GLSKSRELNSGNT---SDSGNSFTTSSPQNKGAMLEN 348
Query: 1810 VTRRRRGGSGYHSRSPARQ-----------ESSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858
++ RG +SP + ++R+S + RS + ++R S S SP
Sbjct: 349 LSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSP 408
Query: 1859 APWKRSRSRASPAT--HRRSRSRTPLIS----RRRSRSRTSPVSRRRSRSRTSVTRRRSR 1912
P R S +T +RS SR+P S +R SR+S R S SR S +R R
Sbjct: 409 NPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDP 468
Query: 1913 SRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRR--- 1969
+ S++R R R RRR RS +P +RR S + RR + +R P+ R
Sbjct: 469 KYSEKDSQQRERER----ARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSP 524
Query: 1970 -SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRR 2028
S S + S S + +R SRSR+ +RRRSR+RTS + RS S P R
Sbjct: 525 SSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPS---PGSRS 581
Query: 2029 RSRSRTPLLPRKRSRSRS 2046
RSRSR+ R RS+SRS
Sbjct: 582 RSRSRSRSRSRSRSQSRS 599
Score = 129 bits (324), Expect = 4e-29
Identities = 166/542 (30%), Positives = 235/542 (43%), Gaps = 76/542 (14%)
Query: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG----PSPEGSSSTESSPEHPPKSR 1666
A R S S P+ R ++ +S + R PSP +SS +H +
Sbjct: 88 ATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
Query: 1667 TARRGSRSSPEPKTKSRTPPR-RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR 1725
+++ SS PK+K R R ++ SRS P + + R R + SS S RHR
Sbjct: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHR 207
Query: 1726 RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP---------RGLQRSRSR 1776
SPE +KSR RR + + + + P +P RG+
Sbjct: 208 GR----SPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGS 263
Query: 1777 SRREKTRT----TRRRDRS-----GSSQSTSRRRQRSRSRSR----------VTRRRRGG 1817
+ T+T T R RS G+ S+ Q S +RSR +++ R
Sbjct: 264 AADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELN 323
Query: 1818 SGYHSRSPARQESSRTSSRRRRGR--SRTPPTSRKR-SRSRTSPAPWKRSRSRAS--PAT 1872
SG S S S TSS + +G PTSR R SR SP ++S P+T
Sbjct: 324 SGNTSDSG---NSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPST 380
Query: 1873 HRRS------RSRTPLISRRRSRSRTSP---VSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923
R S RS + +R S S SP S R ++SR++ + +RS SR SP +S
Sbjct: 381 ARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSR-SPSYSSKS 439
Query: 1924 RSRTPPVTRRRSRSRTPTTRRRS--RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRR 1981
R+PP RSR R+P+ R S R R P + + S+ R RRR RS SP+ +RR
Sbjct: 440 GKRSPPSRSSRSR-RSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSY-SPMRKRR 497
Query: 1982 SRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKR 2041
S + RR + +R P+ R +S S + + R SRS + R R
Sbjct: 498 RDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYS----RSR 553
Query: 2042 SRSRSPLAIRRRSRSRTPRTARGKRSLTRSP-PAIRRRSASGSSSDRSRSATPPATRNHS 2100
SRSRS RRRSR+RT S +RSP P R RS S S RSRS + +R++S
Sbjct: 554 SRSRS----RRRSRTRT-----SSSSSSRSPSPGSRSRSRSRS---RSRSRSRSQSRSYS 601
Query: 2101 GS 2102
+
Sbjct: 602 SA 603
Score = 127 bits (318), Expect = 2e-28
Identities = 160/586 (27%), Positives = 250/586 (42%), Gaps = 95/586 (16%)
Query: 1607 KPRAAPRAQSGSDSSPEPKAPAPRALPRRS-----RSGSSSK---GRGPSPEGSSSTES- 1657
K A PR +S +S + P PR P+ + + G S K P G++S E
Sbjct: 21 KAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERD 80
Query: 1658 ------------SPEH------PPKSRTARRGSRSSPEPKTKSRT----PPRRRSSRSSP 1695
S H PP SR ++ +S+ + + +S + P +++ +SS
Sbjct: 81 KTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSK 140
Query: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS----SRRRRSASSP 1751
+ R+ S++ R +SSSP+++ R RH++ S S P + + R SR + S S P
Sbjct: 141 KHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQ-SRSRPRKSHRHRHHRCPSRSQSSESRP 199
Query: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQR-------- 1803
+ + RGRSP G + R SRR + + SS+ S+ Q
Sbjct: 200 SSCESRHRGRSPE---EGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARG 256
Query: 1804 ------------SRSRSRVTRRRRGGSGYHS-RSPARQESSRTSSRRRRGRSRTPPT--- 1847
+++ S +T R Y S + S++TSS R RG+ + P+
Sbjct: 257 VITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGL 316
Query: 1848 SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR-RRSRSRTSPV---------SR 1897
S+ R + + + S + +SP SR R SR SP S
Sbjct: 317 SKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSL 376
Query: 1898 RRSRSRTSVTRRRSRSRASPVSR---RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVT 1954
S +R+S + SRS + +R SRS P + R ++SR+ ++ +RS SR+P +
Sbjct: 377 VPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYS 436
Query: 1955 RRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT 2014
+ S R+PP RSR S SR R + + S+ R RRR RS SP+
Sbjct: 437 SK-SGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS-YSPMR 494
Query: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKR----------------SRSRSPLAIRRRSRSRT 2058
+RR S + RR + +R +P R S S S A R SRSR+
Sbjct: 495 KRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRS 554
Query: 2059 PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRT 2104
R+ +RS TR+ + RS S S RSRS + +R+ S SR+
Sbjct: 555 -RSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRS 599
Score = 125 bits (315), Expect = 4e-28
Identities = 157/540 (29%), Positives = 227/540 (42%), Gaps = 80/540 (14%)
Query: 1492 TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSA 1551
TP P SR + + + +R S S S V +K + +R RS S + S
Sbjct: 101 TPPPSSRGKKKKKKSTR-KKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSP 159
Query: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS-GSSPEVKDKPRA 1610
+ R E S+++ R R R S S+SR S SR G SPE K R
Sbjct: 160 KSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRR 219
Query: 1611 APRAQSGSD---SSPEPKAPAPRALPRR-----------SRSGSS-------------SK 1643
+ SPE ++ P + P + + SGS+ S+
Sbjct: 220 RHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSR 279
Query: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPK-TKSRTPPRRRSSRSSPELTRKAR 1702
GR + + T S P S +R + SP +KSR +S S T +
Sbjct: 280 GRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSP 339
Query: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKS------RSSRRR---RSASSPRT 1753
++ + + SP +R R R +SP + E + S RSS + RS+S T
Sbjct: 340 QNKGAMLENLSPTSRGRES-RGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAST 398
Query: 1754 KTTSRRGRSPSPK--PRGLQ-RSRSRSRREKTRTTRRRDRSG--SSQSTSRRRQRSRSRS 1808
+++S RSP+P+ PR Q RS S +R +R+ +SG S S S R +RS S S
Sbjct: 399 RSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYS 458
Query: 1809 RVTRRRRGGSGYHSRSPARQESSRTSSRRR-----RGRSRTPPT---SRKRSRSRTSPAP 1860
R + R Y + ++E R RRR R R R P+ +R+ + +R P P
Sbjct: 459 RYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIP 518
Query: 1861 WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR 1920
+ R SP++ S + S SRS + SR RSRSR SR
Sbjct: 519 YYRP----SPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSR---------------SR 559
Query: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR 1980
RRSR+RT S SR+P+ RSRSR +R RSRSR+ +R S + + TRR
Sbjct: 560 RRSRTRTSS----SSSSRSPSPGSRSRSR----SRSRSRSRSRSQSRSYSSADSYSSTRR 611
Score = 125 bits (313), Expect = 8e-28
Identities = 164/589 (27%), Positives = 241/589 (40%), Gaps = 59/589 (10%)
Query: 409 PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
P PQ++ + P K+ +H ++ P + RE+ ++ R H A
Sbjct: 43 PRTEPQNNPVVPAQDGPSE-KLGQHLATEPLGTNSWERDKTCRELGAT-----RGHS-AS 95
Query: 469 RDKSHSHTPSRRMGRSRSPATAKRGR---SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRS 525
DK + PS R + + +T K+ R S S +P K+ +S RR RS
Sbjct: 96 HDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRR--------RS 147
Query: 526 RSPQRRGRSRSPQRPGWSRSRNT-QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRS 584
S +RR S SP+ R+ Q R R R + R R H R P+ S SR + R
Sbjct: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHH-RCPSRSQSSESRPSSCESRH 206
Query: 585 RSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS 644
R R+P + R +RR S++ SR P++ R + S +
Sbjct: 207 RGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAAD 266
Query: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704
+++ +P R RS+ G S P+ ++ +RSR G+ + +P G S+S
Sbjct: 267 LFTKTASPLTTSRGRSQE-YDSGNDTSSPPSTQTSSARSR-----GQEKG-SPSGGLSKS 319
Query: 705 RSLVRRGRSHS------RTPQRRGRSGSSSERKNKSRTSQ-RRSRSNSSP-----EMKKS 752
R L S S +PQ +G + +N S TS+ R SR SP E+KKS
Sbjct: 320 RELNSGNTSDSGNSFTTSSPQNKG-----AMLENLSPTSRGRESRGFQSPCLECAEVKKS 374
Query: 753 RISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPP 812
+ +RS S + RS S SS P ++ +SRS SS+ ++ SR+P
Sbjct: 375 SLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPS 434
Query: 813 RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC 872
S+S PP + S++ S+S SP + P+ S Q + +RRS
Sbjct: 435 YSSKSGKRSPPSRSSRSRRSPSYSRYSPSRE----RDPKYSEKDSQQRERERARRRRRS- 489
Query: 873 FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932
SP + + +PS + R + R SPS S S S RS S
Sbjct: 490 --YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR 547
Query: 933 SSSPSPSRVTSRTTPR-------RSRSVSPCSNVESRLLPRYSHSGSSS 974
S S S SR SR R SRS SP S SR R S S S S
Sbjct: 548 SYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR-SRSRSRS 595
Score = 111 bits (277), Expect = 1e-23
Identities = 157/585 (26%), Positives = 237/585 (40%), Gaps = 117/585 (20%)
Query: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV------NPPSEASPTRDR 403
P P+ + P P+ L + + +PL T ++ AS +D
Sbjct: 43 PRTEPQNNPVVPAQDGPSEKLGQHL--ATEPLGTNSWERDKTCRELGATRGHSASHDKDL 100
Query: 404 SPP------KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSP 457
+PP K +K + SS SP P K + SS + + + R SSSP
Sbjct: 101 TPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSK-KRRHSSSSP 159
Query: 458 TSKNRSHGRAKRD------KSHSHT----PSRRMGRSRSPATAKRGRSRSRTP-----TK 502
SK R R K+ KSH H PSR P++ + R R R+P ++
Sbjct: 160 KSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCE-SRHRGRSPEEGQKSR 218
Query: 503 RGHSR-------SRSPQWRRSR-----------------------SAQRWGRSRSPQRRG 532
R HSR SP+ + SR +A + ++ SP
Sbjct: 219 RRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTS 278
Query: 533 RSRSPQ--------RPGWSRSRNTQRRGRSR-SARRGRSHSR-----------------S 566
R RS + P +++ + + RG+ + S G S SR S
Sbjct: 279 RGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSS 338
Query: 567 PATRGRS-RSRTPARRGRSRS--RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARR 623
P +G + +P RGR ++P + + + S +R+ +G SRS + A
Sbjct: 339 PQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAST 398
Query: 624 RSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRS 683
RS + S SRS +P ++SR+ + RS SR+P+ +S R+P RS RSR
Sbjct: 399 RSSSHS-----SRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR- 452
Query: 684 RTPA--RRGRSRSRTPRRGRSRSRSLVR---RGRSHSRTPQRRGRSGSSSERKNKSRTSQ 738
R+P+ R SR R P+ S+ R R R S +P R+ R S S + + TS
Sbjct: 453 RSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSA 512
Query: 739 RRSRS---NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795
R+ SP S S+ S SS RS ++S S RS S S R
Sbjct: 513 RKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRS-YSRSRSRSRSR-----------R 560
Query: 796 RSRS-GSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSS 839
RSR+ SS ++S +P RSRS S + +S++ SR S+ S
Sbjct: 561 RSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADS 605
Score = 110 bits (276), Expect = 1e-23
Identities = 160/573 (27%), Positives = 209/573 (36%), Gaps = 100/573 (17%)
Query: 1315 KELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQ 1374
+ L+ PL NS+ R G G S+ +DL P + K++
Sbjct: 65 QHLATEPLGTNSWERDKTCRELGA-----TRGHSASHDKDLTPP-----PSSRGKKKKKK 114
Query: 1375 STRSSGHSSSELSPDAVEKAGMSSNQ--------------SISSPVLDAVPRTPSRERSS 1420
STR SS SP V+K S++ S SSP + R R +
Sbjct: 115 STRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSP--KSKRRDEKRHKKQ 172
Query: 1421 SASSPEM--KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSR-GR 1477
S S P + R PSR S S P S SRH G K R R +
Sbjct: 173 SRSRPRKSHRHRHHRCPSRSQSSESRP-----SSCESRHRGRSPEEGQKSRRRHSRRCSK 227
Query: 1478 SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL---- 1533
+ C SPE ++ SR PS P L+ + +GS S+ D T +PL
Sbjct: 228 TLCKDSPEAQS--------SRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSR 279
Query: 1534 GQRSRSGSSQELDVKPS---ASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS- 1589
G+ S + PS +S + R + SP L + S S + S
Sbjct: 280 GRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSP 339
Query: 1590 --------RLSP----RRSRSGSSP-----EVKDKPRAAPRAQSGS-------------- 1618
LSP R SR SP EVK A+S
Sbjct: 340 QNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTR 399
Query: 1619 DSSPEPKAPAPRALPR--RSRSGSSSK---GRGPSPEGSSSTESSPEHPPKSRTARRGSR 1673
SS ++P PRA PR +SRS SS K R PS S S P +SR + SR
Sbjct: 400 SSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSR 459
Query: 1674 SSP----EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS 1729
SP +PK + +R R+ + + +R R + S E R T R R P
Sbjct: 460 YSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPY 519
Query: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
P P+ S SS +++ SR RSRSRSRR T
Sbjct: 520 YR-PSPSSSGSLSSTSSWYSSSSSRSASRS--------YSRSRSRSRSRRRSRTRTSSSS 570
Query: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
S S SR R RSRSRSR +R R Y S
Sbjct: 571 SSRSPSPGSRSRSRSRSRSR-SRSRSQSRSYSS 602
Score = 106 bits (264), Expect = 4e-22
Identities = 171/669 (25%), Positives = 263/669 (39%), Gaps = 105/669 (15%)
Query: 168 PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR 227
P+P S++ S ++R P P+ + + + P ++ + +E
Sbjct: 26 PRPESIIVASITARKPLPRTEPQ---------NNPVVPAQDGPSEKLGQHLATEPLGTNS 76
Query: 228 KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTH 287
R T + ++ + TP P SR + + T + R RS++
Sbjct: 77 WERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKS-------TRKKRRRSSSY--- 126
Query: 288 TTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA 347
SPSP ++ + + S +R S + P S D+ + KK+ S
Sbjct: 127 -------SPSPVKKKKKKSSKKHKRRRSFSKKRRHS----SSSPKSKRRDEKRHKKQ-SR 174
Query: 348 TRPSPS--------PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASP 399
+RP S P RS + P+ RH G P E
Sbjct: 175 SRPRKSHRHRHHRCPSRSQSSESRPSSCE---SRHRG---------------RSPEEGQK 216
Query: 400 TRDRSPPKSPEKLPQSS-SSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT 458
+R R + + L + S ++SS P QP ++ + S+ A + +S T
Sbjct: 217 SRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLT 276
Query: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518
+ S GR++ S + T S ++ S R R + + G S+SR +
Sbjct: 277 T---SRGRSQEYDSGNDTSSPPSTQTSSA----RSRGQEKGSPSGGLSKSRELNSGNTSD 329
Query: 519 AQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP 578
+ + SPQ +G P SR + RG +S S +R+
Sbjct: 330 SGNSFTTSSPQNKGAMLENLSP---TSRGRESRGFQSPCLECAEVKKSSLVP--STARSS 384
Query: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSP-VRRRSRS 637
+G SRS + A RS S + R R R +SRS T + +RS +RSP +S
Sbjct: 385 PMKGCSRSSSYASTRSSSHSS--RSPNPRASPRYTQSRS-TSSEKRSYSRSPSYSSKSGK 441
Query: 638 RSPARRSGRSRSRTPA--RRGRSRSRTP---ARRGRSRSRTPARRSGRSRSRTPARRGRS 692
RSP RS RSR R+P+ R SR R P + + R R ARR R RS +P R+
Sbjct: 442 RSPPSRSSRSR-RSPSYSRYSPSRERDPKYSEKDSQQRERERARR--RRRSYSPMRK--- 495
Query: 693 RSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKS 752
RR S S RR S + P R SS S +S S
Sbjct: 496 -----RRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSS----------- 539
Query: 753 RISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGS-SQPKAKSRTP 811
SS RS S S RS+++SR S RRS + +S +S +P RSRS S S+ +++SR+
Sbjct: 540 --SSSRSASRSYSRSRSRSR-SRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQ 596
Query: 812 PRRSRSSSS 820
R S+ S
Sbjct: 597 SRSYSSADS 605
Score = 94.4 bits (233), Expect = 1e-18
Identities = 152/628 (24%), Positives = 233/628 (37%), Gaps = 105/628 (16%)
Query: 567 PATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR 626
P T ++ PA+ G S + + T R +T G +R + + +
Sbjct: 43 PRTEPQNNPVVPAQDGPSEKL--GQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDL 100
Query: 627 TRSPVRR--RSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
T P R + + +S ++ RS S +P+ + + ++ + R RS + RR S
Sbjct: 101 TPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSS--- 157
Query: 685 TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN 744
+P + R R ++ RSR R R H R P R SSE + S S+ R RS
Sbjct: 158 SPKSKRRDEKRHKKQSRSRPRKSHRH--RHHRCPSR----SQSSESRPSSCESRHRGRSP 211
Query: 745 SSPEMKKSRISSRRSRSLSSPRSKAKSR------------LSLRRSLSGSSPCPK--QKS 790
+ + R S R S++L +A+S LS R ++GS K+
Sbjct: 212 EEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKT 271
Query: 791 QTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP 850
+P SR S + + + T SSPP Q S SR S P
Sbjct: 272 ASPLTTSRGRSQEYDSGNDT--------SSPPSTQTSSARSRGQEKGS-----------P 312
Query: 851 RQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS 910
G S + N + + S SSP +++ + S +S R QSP
Sbjct: 313 SGGLSKSRELNSGNTSDSGNSFTTSSP----QNKGAMLENLSPTSRGRESRGF---QSPC 365
Query: 911 RSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHS 970
+ K + S + S S S S ++R++ SRS +P R PRY+ S
Sbjct: 366 LECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNP------RASPRYTQS 419
Query: 971 GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSG---SKSPCPQEKSKDSLVQ 1027
S+S + + +P S SG SP P +++ PS S S+ P+ KDS +
Sbjct: 420 RSTSSEKRSYSRSPSYSSKSGKRSP-PSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQR 478
Query: 1028 S--------------------CPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH 1067
P L + S+ Y+ S S TS +
Sbjct: 479 ERERARRRRRSYSPMRKRRRDSPSHLE-ARRITSARKRPIPYYRPSPSSSGSLSSTSSWY 537
Query: 1068 RSDTSSPEVR---QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
S +S R +S S S S + + SRS SP + SRS
Sbjct: 538 SSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRS------------ 585
Query: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNS 1152
S +SR +S S SY + DS S
Sbjct: 586 ------RSRSRSRSRSQSRSYSSADSYS 607
Score = 93.2 bits (230), Expect = 3e-18
Identities = 116/461 (25%), Positives = 190/461 (41%), Gaps = 42/461 (9%)
Query: 1695 PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTK 1754
PE A ++ R + P+ P + S + E ++ R +
Sbjct: 28 PESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELG 87
Query: 1755 TTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRR 1814
T RG S S SR +++K ++TR++ R SS S S +++ + S+ +RR
Sbjct: 88 AT--RGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRR 145
Query: 1815 RGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR 1874
R S S + +S R +R + +SR+ P R R P+ + S SR S +
Sbjct: 146 RSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPS-SCES 204
Query: 1875 RSRSRTPLISRRRSRSRTSPVSRRRSRS--RTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
R R R+P ++ R SRR S++ + S + SR + P+ S +T
Sbjct: 205 RHRGRSPEEGQKSRRRH----SRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITG 260
Query: 1933 RRS------RSRTPTTRRRSRSR---------TPPVTRRRSRSRTPPVTRRRSRSRTSP- 1976
S ++ +P T R RS+ +PP T+ S R R + + SP
Sbjct: 261 SGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSS-------ARSRGQEKGSPS 313
Query: 1977 --ITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTR-RRSRSRTPPAIRRRSRSR 2033
+++ R + + S + +SP + SP +R R SR P + +
Sbjct: 314 GGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKK 373
Query: 2034 TPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRS-AT 2092
+ L+P +RS SP+ RS S + S + +P A R + S S+S RS +
Sbjct: 374 SSLVP-STARS-SPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSR 431
Query: 2093 PPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSP 2133
P+ + SG R+PP + SR S PS S R R P
Sbjct: 432 SPSYSSKSGKRSPPSRSSRSRRS----PSYSRYSPSRERDP 468
Score = 80.1 bits (196), Expect = 3e-14
Identities = 135/535 (25%), Positives = 201/535 (37%), Gaps = 72/535 (13%)
Query: 710 RGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNS---SPEMKKSRISSRRSRSLSSPR 766
RG S S S ++K K T ++R RS+S SP KK + SS+
Sbjct: 90 RGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSK--------- 140
Query: 767 SKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP----PRRSRSSSSPP 822
K K R S + SS PK K + R + S+P+ R P RS+SS S P
Sbjct: 141 -KHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRP 199
Query: 823 PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELK 882
+S+ H SP KS R S + S P+ +S S ++
Sbjct: 200 SSCESR------HRGRSPEEGQKSRR--RHSRRCSKTLCKDS--PEAQSSRPPSQPLQML 249
Query: 883 SRTPSRHSCSGSSPPR---VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS 939
+R +GS K+++P S RS S + +SSP PS
Sbjct: 250 GYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYD------------SGNDTSSP-PS 296
Query: 940 RVTSRTTPRRSRSVSPCSNV-ESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPK 998
TS R SP + +SR L + S S + T P+ + + ++SP
Sbjct: 297 TQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQN--KGAMLENLSP--- 351
Query: 999 VKAQTPPGPSLSGSKSPCPQ--EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQ 1056
T G G +SPC + E K SLV S S + +SS SY S
Sbjct: 352 ----TSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSS-----SYASTRSSS 402
Query: 1057 LKGQS---QTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSP 1113
+S + SP + S+ ++S+S SPS SKS RS S + SP
Sbjct: 403 HSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSP 462
Query: 1114 IRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV-----DSNSLLGQSRLETAESKEKM 1168
R+ ++S K E+ R + SY + DS S L R+ +A +
Sbjct: 463 SRERDPKYSE----KDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIP 518
Query: 1169 ALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETK 1223
P ++ S +S + S + R+ R R+ SS ++
Sbjct: 519 YYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSR 573
Score = 74.3 bits (181), Expect = 2e-12
Identities = 93/339 (27%), Positives = 141/339 (41%), Gaps = 19/339 (5%)
Query: 2414 PSQSRMTSERAPSPSSR-MGQAPSQSLLPPAQDQPR-SPVPSAFSDQSRCLIAQTTPVAG 2471
PS+S+ + R S SR G++P + + R S S +++ + P+
Sbjct: 189 PSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQM 248
Query: 2472 SQSLSSGAVATTTSSAGDHNGMLSVP-APGVPHSDVGEPPASTGAQQPSALAALQPAKER 2530
LS+ V T + SA D + P S + T + + ++ + +
Sbjct: 249 LGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQE 308
Query: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
+ S S S S +S ++S S +S +SS ++G+ L + R +P
Sbjct: 309 KGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLEC 368
Query: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
E + P+ R S S SSS +S+ SSS SS S + +S + S S+SS
Sbjct: 369 AEVKKSSLVPSTA-RSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKR 427
Query: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
P K S K+ PP R SRS R P S YSP R P+ S +D
Sbjct: 428 SYSRSPSYSSK--SGKRSPP-SRSSRSRRSPSYS-------RYSPSRER--DPKYSEKDS 475
Query: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
Q ER RR + S SP KRRR++PS R +S
Sbjct: 476 QQRERERARRRRR---SYSPMRKRRRDSPSHLEARRITS 511
Score = 73.6 bits (179), Expect = 3e-12
Identities = 106/391 (27%), Positives = 150/391 (38%), Gaps = 62/391 (15%)
Query: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
R R R+P R S R S + +QS PP+Q P+ +R +I
Sbjct: 205 RHRGRSPEEGQKSRRRHSRRC-SKTLCKDSPEAQSSRPPSQ-----PLQMLGYLSARGVI 258
Query: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
T + L + + T+S G S P S S G ++ S
Sbjct: 259 ---TGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGG 315
Query: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
L ++E S ++S S +S ++SS + + + S +S S P + V +
Sbjct: 316 LSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSS 375
Query: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
P A +P K RSSS +S+ SSS SS S + +S + S S+SS S
Sbjct: 376 LVPSTA-------RSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRS 428
Query: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRK--PIDSLRDS----------RSL 2691
S S +K G ++ P +S + P R R+ P S +DS R
Sbjct: 429 YSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRR 488
Query: 2692 SYSPV-ERRRPSP-------------------QPSPRDQ----------QSSSSERGSRR 2721
SYSP+ +RRR SP +PSP SSSS SR
Sbjct: 489 SYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRS 548
Query: 2722 GQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
R SRS S +R R R SSRSP
Sbjct: 549 YSRSRSRSRSRRRSR----TRTSSSSSSRSP 575
Score = 68.2 bits (165), Expect = 1e-10
Identities = 108/408 (26%), Positives = 147/408 (36%), Gaps = 48/408 (11%)
Query: 2382 SPRVPLSAYERVSGRTSPPLLD---RARSRTPPSAPSQ--SRMTSERAPSPSSRMGQAPS 2436
SP + R S R S L A+S PPS P Q +++ + S +
Sbjct: 210 SPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFT 269
Query: 2437 QSLLPPAQDQPRSPVPSAFSDQSRCLIAQTT-----------PVAG---SQSLSSGAVAT 2482
++ P + RS + +D S QT+ P G S+ L+SG +
Sbjct: 270 KTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSD 329
Query: 2483 -----TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537
TTSS + ML +P S G Q P L+ A+ ++SS S
Sbjct: 330 SGNSFTTSSPQNKGAMLENLSP------TSRGRESRGFQSP----CLECAEVKKSSLVPS 379
Query: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP-----TPAPKEAVRE 2592
++ SS S SSS +S+ SSS S + P R S + +P + +
Sbjct: 380 TARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKS 439
Query: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-------S 2645
G+ P+ + R RRS S S S S S S + S S
Sbjct: 440 GKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRD 499
Query: 2646 SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLS--YSPVERRRPSP 2703
S S A+ A +P +P P S S S SRS S YS R S
Sbjct: 500 SPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSR 559
Query: 2704 QPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
+ S SSSS R G R SRS S R R R S S
Sbjct: 560 RRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYS 607
Score = 66.6 bits (161), Expect = 3e-10
Identities = 96/355 (27%), Positives = 138/355 (38%), Gaps = 44/355 (12%)
Query: 2326 SSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAAL-----APASLTSARMAPALSGANL 2380
SSR P P ++G SA I GS +AA L +P + + R SG +
Sbjct: 238 SSRPPSQPLQ--MLGYLSARGV----ITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDT 291
Query: 2381 TSPRVPLSAYERVSGR---------------TSPPLLDRARSRTPPSAPSQSRMTSERAP 2425
+SP ++ R G+ S D S T S ++ M +P
Sbjct: 292 SSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSP 351
Query: 2426 SPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS 2485
+ R + L A+ + S VPS A+++P+ G SS A ++S
Sbjct: 352 TSRGRESRGFQSPCLECAEVKKSSLVPST---------ARSSPMKGCSRSSSYASTRSSS 402
Query: 2486 SAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS 2545
+ + P S E + + + S+ + + R S S S S S S
Sbjct: 403 HSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSP 462
Query: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR-EGRPPEPTPAKRK 2604
S S S + E + + +++ +P+ EA R P P R
Sbjct: 463 SRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRP 522
Query: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--------SSSSSSSSPSP 2651
SSS S SS+SS SSSSS S+S S S S S S S SSSSSS SPSP
Sbjct: 523 SPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSP 577
Score = 60.8 bits (146), Expect = 2e-08
Identities = 60/181 (33%), Positives = 84/181 (46%), Gaps = 34/181 (18%)
Query: 157 AREAKQPAPEPPKPYSLVRESSS-----SRSPTPKQKKKKK----KKDRGRRSESSS--- 204
+ ++ P P Y+ R +SS SRSP+ K K+ + R RRS S S
Sbjct: 402 SHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYS 461
Query: 205 PRRERK-KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTT----------- 252
P RER K S+K + E E +R+ RS +P KR+ +R T
Sbjct: 462 PSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYR 521
Query: 253 PAPKSRRAHRSTSADSASSSDTS--------RSRSRS-AAAKTHT-TALAGRSPSPASGR 302
P+P S + STS+ +SSS S RSRSRS ++T T ++ + RSPSP S
Sbjct: 522 PSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS 581
Query: 303 R 303
R
Sbjct: 582 R 582
Score = 45.4 bits (106), Expect = 8e-04
Identities = 49/202 (24%), Positives = 79/202 (39%), Gaps = 40/202 (19%)
Query: 111 TPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
+P R + T + +EK++ ++ S G P R +R + P+
Sbjct: 407 SPNPRASPRYTQSRSTSSEKRSYSRSPSY----SSKSGKRSPPSRSSRSRRSPSYSR--- 459
Query: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR-KH 229
YS RE S Q++++++ R RRS S +R R S + R S K+ +
Sbjct: 460 YSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPY 519
Query: 230 RSPTPKS------------------------KRKSKDKKRKRSRSTT--------PAPKS 257
P+P S + +S+ + R+RSR+ T P+P S
Sbjct: 520 YRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGS 579
Query: 258 RRAHRSTSADSASSSDTSRSRS 279
R RS S + S SRS S
Sbjct: 580 RSRSRSRSRSRSRSRSQSRSYS 601
Score = 42.0 bits (97), Expect = 0.008
Identities = 116/545 (21%), Positives = 184/545 (33%), Gaps = 66/545 (12%)
Query: 988 SHSGSISPYP------KVKAQTPPGPSLSGSKSPCP--QEKSKDSLVQSCPGSLSLCAGV 1039
SH ++P P K K T S S SP P ++K K S S S
Sbjct: 95 SHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRH 154
Query: 1040 KSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRS 1099
SS+P + + K QS++ P R H PS S++ P S
Sbjct: 155 SSSSPKSKRR---DEKRHKKQSRSRPRKSH-------RHRHHRCPSRSQSSESRPSSCES 204
Query: 1100 RSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRL 1159
R E +S R R + + K + SR S P L + +
Sbjct: 205 RHRGRSPEEGQKSRRRHSRR--CSKTLCKDSPEAQSSR----PPSQPLQMLGYLSARGVI 258
Query: 1160 ETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER-SGAGS 1218
+ S + T S R ++ S P + + R+ +E+ S +G
Sbjct: 259 TGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQT---SSARSRGQEKGSPSGG 315
Query: 1219 SPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESS----PEV 1274
+++E NS + S + S + G +L +LS + + F+S EV
Sbjct: 316 LSKSRELNSGNTSDSGNS----FTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEV 371
Query: 1275 EERPAVSLTLDQSQSQ-----ASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG- 1328
++ V T S + +S + S +S P SP + + ++ + S+
Sbjct: 372 KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSR 431
Query: 1329 SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSEL-- 1386
SP SG + S + + E DP K+ R +
Sbjct: 432 SPSYSSKSGKRSPPSRSSRSR--RSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS 489
Query: 1387 ----------SPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
SP +E ++S + P +PS S S++S R+ S
Sbjct: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRP---SPSSSGSLSSTSSWYSSSSSRSAS 546
Query: 1437 R-------RSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKAL 1489
R RSRS R S + SR GS + R+ SR RS+ S +
Sbjct: 547 RSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSY 606
Query: 1490 PQTPR 1494
T R
Sbjct: 607 SSTRR 611
Score = 38.1 bits (87), Expect = 0.12
Identities = 58/244 (23%), Positives = 78/244 (31%), Gaps = 36/244 (14%)
Query: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
D+ PP+S G ++ K+RR SSS S S SS S
Sbjct: 99 DLTPPPSSRGKKKKKK----STRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRH 154
Query: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
SS +PK R+ + + R R+S S S SS S
Sbjct: 155 SSS-----------------SPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSES 197
Query: 2625 SSSSSSS-----SSSSSSSSSSSSSSSSSPSPAKPGPQA-LPKPASPKKPPPGERRSRSP 2678
SS S S S S S + K P+A +P S G +R
Sbjct: 198 RPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGV 257
Query: 2679 RKPIDSLRDSRSLSYSPVERRRPSPQ---------PSPRDQQSSSSERGSRRGQRGDSRS 2729
S D + + SP+ R Q P Q SS+ RG +G S
Sbjct: 258 ITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLS 317
Query: 2730 PSHK 2733
S +
Sbjct: 318 KSRE 321
Score = 37.7 bits (86), Expect = 0.16
Identities = 49/153 (32%), Positives = 61/153 (39%), Gaps = 24/153 (15%)
Query: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
K R ++ S+S + SS S+ SSS SPSP K K
Sbjct: 81 KTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKK-----KK 135
Query: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
S KK RRS S ++ R S SP +RR + +QS S R S R
Sbjct: 136 KKSSKKHK--RRRSFSKKR--------RHSSSSPKSKRRDEKR---HKKQSRSRPRKSHR 182
Query: 2722 GQ--RGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
+ R SRS S + R PS RHR RSP
Sbjct: 183 HRHHRCPSRSQSSESR---PSSCESRHR-GRSP 211
Score = 37.0 bits (84), Expect = 0.27
Identities = 42/162 (25%), Positives = 55/162 (33%), Gaps = 14/162 (8%)
Query: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
TP P G+ + ++KRR SSS S S SS S S SSS
Sbjct: 101 TPPPSS---RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSS 157
Query: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPS 2702
S S + Q+ +P + R R P + S +SR S R R
Sbjct: 158 SPKSKRRDEKRHKKQSRSRPRKSHR----HRHHRCPSRSQSS--ESRPSSCESRHRGR-- 209
Query: 2703 PQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPM 2744
SP + Q S R + SP + R P M
Sbjct: 210 ---SPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQM 248
Score = 33.5 bits (75), Expect = 3.0
Identities = 46/218 (21%), Positives = 70/218 (32%), Gaps = 23/218 (10%)
Query: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
G++ S + P + + + ++ R P+P K+K++ SS
Sbjct: 87 GATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRR 146
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP---PGER 2673
S S SSSS S S S S + + S + P
Sbjct: 147 SFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRH 206
Query: 2674 RSRSPR-----KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERG--SRRGQRGD 2726
R RSP + S R S++L E + P P S RG + G D
Sbjct: 207 RGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAAD 266
Query: 2727 -------------SRSPSHKRRRETPSPRPMRHRSSRS 2751
RS + +T SP + S+RS
Sbjct: 267 LFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARS 304
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 160 bits (404), Expect = 2e-38
Identities = 173/509 (33%), Positives = 235/509 (46%), Gaps = 80/509 (15%)
Query: 300 SGRRGEGDAPFS-EPGTTSTQRPSSPETA-TKQPSSPYE------DKDKDKKEKSATRPS 351
+G PF+ EP T T + TA T + Y+ +D + +T PS
Sbjct: 1589 AGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMVISTSPS 1648
Query: 352 PSPERSSTGPEPPAPTPL-------LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404
E GP P L L + P P+ + + + P E+S
Sbjct: 1649 GGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSPKESSGGEKEV 1708
Query: 405 PPKSPEKLPQSSSSES----------SPPSPQPTKVSRHASSSPESPKPAPAPGSHRE-- 452
PP E LP S S + P P+ + + E P A G R
Sbjct: 1709 PPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAA 1768
Query: 453 ---ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS-RS 508
+SS P + S K D + ++ + + + R + KR S RS
Sbjct: 1769 SPVVSSMPERASESSSEEKDD----YEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRS 1824
Query: 509 RSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPA 568
RS +RS+S++ R R+ + R R+R +R S+S +Q R RSRS RR RS
Sbjct: 1825 RS---KRSKSSEHKSRKRTSESRSRAR--KRSSKSKSHRSQTRSRSRSRRRRRS------ 1873
Query: 569 TRGRSRSRTPARRGRS---RSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS 625
RSRS++ RR S R R+P + RS+SR R+RS SR + R+RSRTP+RR S
Sbjct: 1874 --SRSRSKSRGRRSVSKEKRKRSP-KHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR-S 1929
Query: 626 RTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRT 685
R+ +P RRR RSRS RR RS S +P+RR SRTP+RR SRTP+RRS RT
Sbjct: 1930 RSHTPSRRR-RSRSVGRR--RSFSISPSRR----SRTPSRR----SRTPSRRS-----RT 1973
Query: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNS 745
P+R RSRTP R RSR+ RR SRTP RR RS S R++ S + R RS +
Sbjct: 1974 PSR----RSRTPSR---RSRTPSRR----SRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 746 SPEMKKSRISSRRSRSLSSPRSKAKSRLS 774
+ SR RR RS SS R ++ RL+
Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKRLT 2051
Score = 140 bits (353), Expect = 2e-32
Identities = 123/328 (37%), Positives = 169/328 (51%), Gaps = 51/328 (15%)
Query: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWS----------RSRNTQRRGRSRSARRGRSHS 564
R RSA S P+R S S ++ + +S+ + R + ++ S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 565 RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRR 624
RS + R +S S +R+ S SR+ AR+RS R ++RSR+ +RR R SR+ R +
Sbjct: 1823 RSRSKRSKS-SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRS--RSK 1879
Query: 625 SRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
SR R V + R RSP RS +SR R +R RS SR + R+RSRTP+RRS RS
Sbjct: 1880 SRGRRSVSKEKRKRSPKHRS-KSRER---KRKRSSSRDNRKTVRARSRTPSRRS---RSH 1932
Query: 685 TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN 744
TP+RR RSRS RR S S S SRTP RR R+ S +SRT RRSR+
Sbjct: 1933 TPSRRRRSRSVGRRRSFSISPS------RRSRTPSRRSRTPS-----RRSRTPSRRSRTP 1981
Query: 745 SSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQP 804
S ++SR SRRSR +P + +SR +RR SP ++S+TP RR
Sbjct: 1982 S----RRSRTPSRRSR---TPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRR-------- 2026
Query: 805 KAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
SR+P RR RS SS ++ ++P R
Sbjct: 2027 -RFSRSPIRRKRSRSS----ERGRSPKR 2049
Score = 137 bits (344), Expect = 2e-31
Identities = 246/1085 (22%), Positives = 385/1085 (35%), Gaps = 183/1085 (16%)
Query: 854 SITSPQANEQSVTPQRRSCFE----SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909
S+ SP A ++ RS S P + S + S S +P
Sbjct: 1023 SMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRS 1082
Query: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSH 969
S + + S RS S S + + S T RS + Y+
Sbjct: 1083 MMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTE 1142
Query: 970 SGSSSPDTKVKPET-PPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQS 1028
+ P +P T PP ++P P + P GP+L +S E + + V S
Sbjct: 1143 AYMVPPLPPEEPPTMPPLPPEEPPMTP-PLPPEEPPEGPALPTEQSALTAENTWPTEVPS 1201
Query: 1029 CPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS------- 1081
P S V PP VS ++ S D+ S P V S +
Sbjct: 1202 SPSEES----VSQPEPP------VSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEP 1251
Query: 1082 -------------ESPSLQSKSQTSPK-------GGRSRSSSPVTELASRSPIRQDRGEF 1121
ES + + + P+ S+ T LAS P+ + E
Sbjct: 1252 PPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAET 1311
Query: 1122 SAS----------------------PMLKSGMSPEQSRFQSDSSSYPTVDSNSL--LGQS 1157
S P+L + + +SS+ ++S+++ L S
Sbjct: 1312 FDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESS 1371
Query: 1158 RLETAESKEKMALPPQEDATASPP--RQKDKFS-PFPVQD---------RPESSLVFKDT 1205
+ ES L P PP + D + P PV P S++
Sbjct: 1372 TVTVLESSTVTVLEPSVVTVPEPPVVAEPDYVTIPVPVVSALEPSVPVLEPAVSVLQPSM 1431
Query: 1206 LRTPP----RERSGAGSSPET--KEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSE 1259
+ + P +E + S P EQ +PT E ++E S + SH+
Sbjct: 1432 IVSEPSVSVQESTVTVSEPAVTVSEQTQVIPTEVAIESTPMILESSI-----MSSHVMKG 1486
Query: 1260 LKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSN 1319
+ +S+ + +PE+ + +L + E P G + EH +
Sbjct: 1487 IN-LSSGDQNLAPEI------------GMQEIALHSGEEPHAEEHLKGDFYESEHGINID 1533
Query: 1320 SPLRENSFGSPLEFRNSGPLGT-------EMNTGFSSEVKEDLNGPFLNQLETDPSLDMK 1372
+ + +E GT E +SE K+ L+T P +
Sbjct: 1534 LNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQR------TVLDTYPGV--- 1584
Query: 1373 EQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL- 1431
S +G + S P A+E +++ I + + S ++ + + +
Sbjct: 1585 --SEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMV 1642
Query: 1432 ----PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPG----MKDIPRTPSRGRSECDSS 1483
P S G P PS ++L +K+ +T + S +SS
Sbjct: 1643 ISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSPKESS 1702
Query: 1484 PEPKALPQTPRPRSRSPSS-----------PELNNKCLTPQRERSGS----------ESS 1522
K +P P P+ P S +L L ER S S
Sbjct: 1703 GGEKEVP--PPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASD 1760
Query: 1523 VDQKTVARTP----LGQRSRSGSSQELD-------VKPSASPQERSESDSSPDSKAKTRT 1571
V + A +P + +R+ SS+E D VK + +++++ + + K +
Sbjct: 1761 VGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDS 1820
Query: 1572 PLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA 1631
LR RS+ S E S+ R S RSR+ R+ R++S R+
Sbjct: 1821 SLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRS-------------RS 1867
Query: 1632 LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE----PKTKSRTPPR 1687
RR S S SK RG + SP+H KSR +R SS + + +SRTP R
Sbjct: 1868 RRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 1688 RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747
R S +P R++R R RS S SP RSRTP R R+PS S P+ +SR+ RR
Sbjct: 1928 RSRSH-TPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR 1986
Query: 1748 ASSPRTKTTSRRGRSPS-PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
S R++T SRR RS S + R S R RR +T RR RS + SR +R RS
Sbjct: 1987 TPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Query: 1807 RSRVT 1811
R+T
Sbjct: 2047 PKRLT 2051
Score = 137 bits (344), Expect = 2e-31
Identities = 146/381 (38%), Positives = 184/381 (48%), Gaps = 57/381 (14%)
Query: 1648 SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS--------RTPPRRRSSRSSPELTR 1699
SP+ SS E PPK G ++ E ++ + R S R+ E
Sbjct: 1697 SPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPL 1756
Query: 1700 KARLSRRSRSA-----SSSPETRSRTPPRHRRSPS--VSSPEPAEKSRSSRRRRSASSPR 1752
A R RSA SS PE S + + V + EKS+ ++ R +
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK 1816
Query: 1753 TKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTR 1812
+ +S R RS K S R++T +R R R SS+S S R Q +RSRSR R
Sbjct: 1817 KRDSSLRSRSKRSK------SSEHKSRKRTSESRSRARKRSSKSKSHRSQ-TRSRSRSRR 1869
Query: 1813 RRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPAT 1872
RRR SRS ++ R+ S+ +R RS P R +SR R KRS SR + T
Sbjct: 1870 RRRS-----SRSRSKSRGRRSVSKEKRKRS---PKHRSKSRERKR----KRSSSRDNRKT 1917
Query: 1873 HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
R +RSRTP RRSRS T P RRRSRS V RRRS S SP R R+ SR
Sbjct: 1918 VR-ARSRTP---SRRSRSHT-PSRRRRSRS---VGRRRSFS-ISPSRRSRTPSRRSRTPS 1968
Query: 1933 RRSR-----SRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTS 1987
RRSR SRTP+ R R+ SR RR RSR+ V RRRS S SP+ RRSR+
Sbjct: 1969 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS--VVRRRSFS-ISPVRLRRSRT--- 2022
Query: 1988 PVTRRRSRSRTSPVTRRRSRS 2008
P+ RR SR SP+ R+RSRS
Sbjct: 2023 PLRRRFSR---SPIRRKRSRS 2040
Score = 129 bits (323), Expect = 5e-29
Identities = 238/934 (25%), Positives = 362/934 (38%), Gaps = 148/934 (15%)
Query: 1120 EFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179
E +SP +S PE QS+ S V ++ + S S+ + +P
Sbjct: 1198 EVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEP------ 1251
Query: 1180 PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPT--SSQDEE 1237
PP + + PV ES++V ++ P ER ET SA PT +S+
Sbjct: 1252 PPEPESSITLTPV----ESAVVAEEHEVVP--ERPVTCMVSETPAM-SAEPTVLASEPPV 1304
Query: 1238 LMEVVEK--SEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEA 1295
+ E E S +G + S +S+ L + + + + E PA++ +S + A LE+
Sbjct: 1305 MSETAETFDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPAMAAP--ESSAMAVLES 1362
Query: 1296 VEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDL 1355
V + SS S L S + + P + + + E +
Sbjct: 1363 SAVTVLESSTVTVLESSTVTVLEPSVV---TVPEPPVVAEPDYVTIPVPVVSALEPSVPV 1419
Query: 1356 NGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPS 1415
P ++ L+ PS+ + E S S E + E A S Q+ P A+ TP
Sbjct: 1420 LEPAVSVLQ--PSMIVSEPSV-----SVQESTVTVSEPAVTVSEQTQVIPTEVAIESTPM 1472
Query: 1416 RERSSSASSPEMKDGLPRTPSRRS------------RSGSSPGLRD---GSGTPSRHSLS 1460
SS SS MK G+ + ++ SG P + G S H ++
Sbjct: 1473 ILESSIMSSHVMK-GINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFYESEHGIN 1531
Query: 1461 ----------------------GSSP-----GMKDIPRTPSRGRSECDSSPEPKALPQTP 1493
G+SP K +P + ++ R+ D+ P + +
Sbjct: 1532 IDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYP---GVSEAD 1588
Query: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQR-----SRSGSSQELDVK 1548
+ S + P + + +G+ ++ T + L + S + E D+
Sbjct: 1589 AGETLSSTGP------FALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMV 1642
Query: 1549 PSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
S SP SE+D AK ++ S + L + + + D+
Sbjct: 1643 ISTSPSGGSEADIEGPLPAKD-----------IHLDLPSNNNLVSKDTEEPLPVKESDQT 1691
Query: 1609 RAA---PRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665
AA P+ SG + P P LP G + E + + PK
Sbjct: 1692 LAALLSPKESSGGEKEVPP--PPKETLP--------DSGFSANIEDINEADLVRPLLPKD 1741
Query: 1666 RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR 1725
R+ E + R RS+ S + R S S E + H
Sbjct: 1742 MERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHE 1801
Query: 1726 RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTT 1785
+S + + EK + + S R+K++ + R + + R R RS + T
Sbjct: 1802 KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT 1861
Query: 1786 RRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP 1845
R R RS + +SR R +SR R V++ +R RSP + SR R+R
Sbjct: 1862 RSRSRSRRRRRSSRSRSKSRGRRSVSKEKR------KRSPKHRSKSRERKRKRSSSRDNR 1915
Query: 1846 PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRS---RS 1902
T R RSR+ P +RSRS +P+ RRSRS + RRRS S SP R R+ RS
Sbjct: 1916 KTVRARSRT-----PSRRSRSH-TPSRRRRSRS----VGRRRSFS-ISPSRRSRTPSRRS 1964
Query: 1903 RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
RT R R+ SR S R RSRTP RSRTP+ RRRSRS V RRRS S
Sbjct: 1965 RTPSRRSRTPSRRSRTPSR--RSRTP-----SRRSRTPSRRRRSRS----VVRRRSFS-I 2012
Query: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRS 1996
PV RRSR +P+ RR SR SP+ R+RSRS
Sbjct: 2013 SPVRLRRSR---TPLRRRFSR---SPIRRKRSRS 2040
Score = 128 bits (321), Expect = 9e-29
Identities = 152/456 (33%), Positives = 201/456 (44%), Gaps = 70/456 (15%)
Query: 1648 SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
SP G S + P K S ++ K P + S ++ L S
Sbjct: 1646 SPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALL--------S 1697
Query: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK- 1766
SS E PP+ S S + + + R + TS R P
Sbjct: 1698 PKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLL 1757
Query: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQS-----------TSRRRQRSRSRSRVTRRRR 1815
+ R RS + + R S S + T + +++++R + + ++
Sbjct: 1758 ASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKK 1817
Query: 1816 GGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR 1875
S SRS R +SS SR+R SR+ +RKRS S RSRSR S R
Sbjct: 1818 RDSSLRSRSK-RSKSSEHKSRKRTSESRS--RARKRSSKSKSHRSQTRSRSR-SRRRRRS 1873
Query: 1876 SRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRR---RSRSRTPPVTR 1932
SRSR S+ R R S R+RS S +R R R R+S R R+RSRTP
Sbjct: 1874 SRSR----SKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPS--- 1926
Query: 1933 RRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRR 1992
RRSRS TP+ RRRSRS V RRRS S +P RRSR+ P R R+ SR S R
Sbjct: 1927 RRSRSHTPSRRRRSRS----VGRRRSFSISPS---RRSRT---PSRRSRTPSRRSRTPSR 1976
Query: 1993 RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRR 2052
RSR+ P R R+ SR RSRTP + RRRSRS + R+RS S SP+ +R
Sbjct: 1977 RSRT---PSRRSRTPSR---------RSRTP-SRRRRSRS----VVRRRSFSISPVRLR- 2018
Query: 2053 RSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRS 2088
RSRTP +R +RSP IRR+ + S RS
Sbjct: 2019 --RSRTPL----RRRFSRSP--IRRKRSRSSERGRS 2046
Score = 127 bits (320), Expect = 1e-28
Identities = 121/408 (29%), Positives = 177/408 (43%), Gaps = 55/408 (13%)
Query: 523 GRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRG 582
GR RS S P+R S S + ++ + +H +S + R + +R
Sbjct: 1762 GRDRSAASPVVSSMPERA--SESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 583 RSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPAR 642
S R RS+ + +SR RT R R+R R+ + R+++ R RSR R R
Sbjct: 1820 SS-----LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR---R 1871
Query: 643 RSGRSRSRTPARRGRS---RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRR 699
RS RSRS++ RR S R R+P R +SR R R S R +T R+RSRTP R
Sbjct: 1872 RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV----RARSRTPSR 1927
Query: 700 GRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRS 759
RS S TP RR RS S R++ S + RRSR+ S ++SR SRRS
Sbjct: 1928 ------------RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPS----RRSRTPSRRS 1971
Query: 760 RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSS 819
R+ S RS+ SR S P ++S+TP RR RS S + P R R S
Sbjct: 1972 RT-PSRRSRTPSR---------RSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSR 2021
Query: 820 SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP 879
+P ++ S++P R+ S SS + +P R + Q E + C
Sbjct: 2022 TPLRRRFSRSPIRRKRSRSSE----RGRSPKRLTDLDKAQLLEIAKANAAAMC------- 2070
Query: 880 ELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQ 927
K+ P + + PP ++ + + K K I ++
Sbjct: 2071 -AKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKE 2117
Score = 109 bits (272), Expect = 4e-23
Identities = 99/252 (39%), Positives = 126/252 (50%), Gaps = 18/252 (7%)
Query: 1884 SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTR 1943
S RSRS+ S S +SR RTS +R R+R R+S RS++R +R RSR R ++R
Sbjct: 1820 SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR----SRSRSRRRRRSSR 1875
Query: 1944 RRSRSRTPPVTRRRSRSRTP---PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
RS+SR + R R+P +R R R R+S R++ S RRSRS T P
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHT-P 1934
Query: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP- 2059
RRRSRS V RRRS S P+ R R+ SR P +RSR+ S + RSRTP
Sbjct: 1935 SRRRRSRS----VGRRRSFS-ISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS 1989
Query: 2060 RTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119
R +R RS +RRRS S S RS T P R S S P+ SR S R
Sbjct: 1990 RRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT-PLRRRFSRS---PIRRKRSRSSERGR 2045
Query: 2120 PSMSPTPLDRCR 2131
T LD+ +
Sbjct: 2046 SPKRLTDLDKAQ 2057
Score = 102 bits (254), Expect = 5e-21
Identities = 86/280 (30%), Positives = 137/280 (48%), Gaps = 32/280 (11%)
Query: 664 ARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGR 723
+++ ++R + + S R+ ++R +S R+ S SRS R+ S S++ + + R
Sbjct: 1803 SKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR 1862
Query: 724 SGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783
S S S R+ +S S+ +SR S +K + S + RSK++ R R S +
Sbjct: 1863 SRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKH-------RSKSRERKRKRSSSRDNR 1915
Query: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK 843
+ +S+TP RRSRS + + +SR+ RR S SP ++S+TPSR+S + P
Sbjct: 1916 KTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP--SRRSRTPSRRSRT-----PS 1968
Query: 844 VKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRV-KSS 902
+S TP R+ S + +S TP RRS +P +SR+ R SP R+ +S
Sbjct: 1969 RRSRTPSRR----SRTPSRRSRTPSRRS---RTPSRRRRSRSVVRRRSFSISPVRLRRSR 2021
Query: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVT 942
TP R+ SRS R+RS S SP R+T
Sbjct: 2022 TPLRRRFSRSP----------IRRKRSRSSERGRSPKRLT 2051
Score = 95.9 bits (237), Expect = 5e-19
Identities = 102/332 (30%), Positives = 141/332 (42%), Gaps = 29/332 (8%)
Query: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTS-PVSRRRSRSRTSVTRRRSRSRASPVSRR 1921
R RS ASP + S + V +S+ + R + S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 1922 RSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRR 1981
RSRS+ + +SR RT +R R+R R+ RS++R+ +RRR RS S R +
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRS---RSK 1879
Query: 1982 SRSRTSPVTRRRSRS-RTSPVTRRRSRSRTSPVTRR---RSRSRTPPAIRRRSRSRTPLL 2037
SR R S +R RS + +R R R R+S R R+RSRTP RRSRS TP
Sbjct: 1880 SRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP---SRRSRSHTP-S 1935
Query: 2038 PRKRSRS---RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPP 2094
R+RSRS R +I RSRTP S P+ R R+ S S SR + P
Sbjct: 1936 RRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1995
Query: 2095 ATRNHSGS-------RTPPVALNSSRMSCFSRPSMSP------TPLDRCRSPGMLEPLGS 2141
+ R S S PV L SR R S SP +R RSP L L
Sbjct: 1996 SRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDK 2055
Query: 2142 SRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVP 2173
++ + + + +M G +P + + + P
Sbjct: 2056 AQL-LEIAKANAAAMCAKAGVPLPPNLKPAPP 2086
Score = 88.2 bits (217), Expect = 1e-16
Identities = 97/319 (30%), Positives = 137/319 (42%), Gaps = 36/319 (11%)
Query: 713 SHSRTPQRRGRSGSSSERKNKS--RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
+H ++ + + R E+K S R+ +RS+S+ K++ S R+R S SK+K
Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS---SKSK 1855
Query: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
S S RS S S RR RS S+ K++ R + + SP + KS+
Sbjct: 1856 SHRSQTRSRSRSR-----------RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRER 1904
Query: 831 SRQSHSSSSPHPKV--KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR 888
R+ SS V +S TP R+ +P +S + RR F S P +SRTPSR
Sbjct: 1905 KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSIS--PSRRSRTPSR 1962
Query: 889 HSCSGSSPPRVKSSTPPRQS--PSRSSSPQPKVKAIISPRQRSHS----GSSSPSPSRV- 941
S P +S TP R+S PSR S + S R+RS S S S SP R+
Sbjct: 1963 R----SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLR 2018
Query: 942 TSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKA 1001
SRT RR S SP SR S SP + + + + KA
Sbjct: 2019 RSRTPLRRRFSRSPIRRKRSR-----SSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKA 2073
Query: 1002 QTPPGPSLSGSKSPCPQEK 1020
P P+L + P +EK
Sbjct: 2074 GVPLPPNLKPAPPPTIEEK 2092
Score = 87.0 bits (214), Expect = 2e-16
Identities = 91/416 (21%), Positives = 167/416 (40%), Gaps = 46/416 (11%)
Query: 83 EEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETH---QLAELNE---------K 130
E ++E T +L K+ + G KE P + + ++ + ++NE K
Sbjct: 1681 EPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPK 1740
Query: 131 KNERLRAA-FGI------SDSYVDGSSFDP--QRRAREAKQPAPEPPKPYSLVRESSSSR 181
ERL + GI SD D S+ P A + + E Y + + +
Sbjct: 1741 DMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTH 1800
Query: 182 SPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESES----KKRKHRSPTPKSK 237
+ K K + K + +R S R +R KSS+ K + SES +KR +S + +S+
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ 1860
Query: 238 RKSKDKKRKRSRSTTPAPKSR-------------RAHRSTSADSASSSDTSRSRSRSAAA 284
+S+ + R+R RS+ KSR HRS S + +SR ++ A
Sbjct: 1861 TRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRA 1920
Query: 285 KTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKE 344
++ T + RS +P+ RR + ++R +P ++ PS + ++
Sbjct: 1921 RSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR--RSRTPSRRS 1978
Query: 345 KSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL----ATTPLSQEPVNPPSEASPT 400
++ +R S +P R S P + + R S P+ + TPL + P +
Sbjct: 1979 RTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRS 2038
Query: 401 RDRSPPKSPEKLPQSSSSE--SSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
R +SP++L ++ + ++ P + KPAP P +++
Sbjct: 2039 RSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVA 2094
Score = 86.7 bits (213), Expect = 3e-16
Identities = 245/1014 (24%), Positives = 384/1014 (37%), Gaps = 216/1014 (21%)
Query: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH 841
SSP + SQ P S+S S+P A P S S+S P S S + + P
Sbjct: 1201 SSPSEESVSQPEPPVSQSEISEPSA---VPTDYSVSASDP-----SVLVSEAAVTVPEPP 1252
Query: 842 PKVKSG---TPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898
P+ +S TP + A E V P+R P + S TP+ S+ P
Sbjct: 1253 PEPESSITLTPVESAVV----AEEHEVVPER-------PVTCMVSETPAM-----SAEPT 1296
Query: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV----- 953
V +S PP S + + S R H S + V + TTP + S+
Sbjct: 1297 VLASEPPVMSET--------AETFDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPA 1348
Query: 954 --SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ----TPPGP 1007
+P S+ + L SS T ++ T S P P V A+ T P P
Sbjct: 1349 MAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVTVPEPPVVAEPDYVTIPVP 1408
Query: 1008 SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH 1067
+S + P + S++Q V+ ST ++ + Q+Q P
Sbjct: 1409 VVSALEPSVPVLEPAVSVLQPSMIVSEPSVSVQESTVT----VSEPAVTVSEQTQVIPTE 1464
Query: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRS---PIRQD--RGEFS 1122
+ S+P + +S S + S + E+A S P ++ +G+F
Sbjct: 1465 VAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFY 1524
Query: 1123 ASPMLKSGMSPE---QSRFQSDSSSYPTVDSNSL-----LGQSR-LETAESKEKMALPPQ 1173
S + G++ + + + + TV + +G+ + L T+E+K++ L
Sbjct: 1525 ES---EHGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTY 1581
Query: 1174 EDAT-ASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTS 1232
+ A PF ++ P+++ K E + A + + + L +
Sbjct: 1582 PGVSEADAGETLSSTGPFALE--PDATGTSKGI------EFTTASTLSLVNKYDVDLSLT 1633
Query: 1233 SQDEELMEVVEKSEEPAGQILSHLSSELK------EMSTSNFESSPEVEERPAVSLTLDQ 1286
+QD E V+ S P+G + + L ++ ++N S + EE L
Sbjct: 1634 TQDTEHDMVI--STSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEE------PLPV 1685
Query: 1287 SQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTG 1346
+S +L A+ P SS G P KE T ++G
Sbjct: 1686 KESDQTLAALLSPK-ESSGGEKEVPPPPKE------------------------TLPDSG 1720
Query: 1347 FSSEVKE----DLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSI 1402
FS+ +++ DL P L + DM+ ++ +G L+ D + ++S
Sbjct: 1721 FSANIEDINEADLVRPLLPK-------DMERLTSLRAGIEGPLLASD------VGRDRSA 1767
Query: 1403 SSPVLDAVPRTPSRERSSSASSPE---------MKDGLPRTPSRRSRSGSSPGLRDGSGT 1453
+SPV+ ++P ER+S +SS E +KD ++ ++R + S
Sbjct: 1768 ASPVVSSMP-----ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 1454 PSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQ 1513
SR S SS + SR R+ SS QT R RSRS +
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT-RSRSRS-------------R 1868
Query: 1514 RERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPL 1573
R R S S K+ R + + R S + + S D+ +A++RTP
Sbjct: 1869 RRRRSSRSR--SKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPS 1926
Query: 1574 RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALP 1633
R+ S+S RR RS R+ R +S S SP ++ P
Sbjct: 1927 RR-----------SRSHTPSRRRRS----------RSVGRRRSFS-ISPSRRSRTP---S 1961
Query: 1634 RRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS 1693
RRSR+ S + R PS +SRT R SR+ P +SRTP RRR SRS
Sbjct: 1962 RRSRT-PSRRSRTPS--------------RRSRTPSRRSRT---PSRRSRTPSRRRRSRS 2003
Query: 1694 SPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747
+ RRS S S RSRTP R R S SP ++SRSS R RS
Sbjct: 2004 V--------VRRRSFSISPVRLRRSRTPLRRRFS---RSPIRRKRSRSSERGRS 2046
Score = 62.4 bits (150), Expect = 6e-09
Identities = 126/534 (23%), Positives = 195/534 (36%), Gaps = 79/534 (14%)
Query: 1222 TKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKE-MSTSNFESSPE-VEERPA 1279
+K+ LP D+ L ++ E G+ + KE + S F ++ E + E
Sbjct: 1676 SKDTEEPLPVKESDQTLAALLSPKESSGGE--KEVPPPPKETLPDSGFSANIEDINEADL 1733
Query: 1280 VSLTLDQSQSQ-ASLEA-VEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSG 1337
V L + + SL A +E P +AS G R+ S SP+ +S
Sbjct: 1734 VRPLLPKDMERLTSLRAGIEGPLLASDVG----------------RDRSAASPVV--SSM 1775
Query: 1338 PLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMS 1397
P E + SSE K+D F+ +T K+ R G + ++ S
Sbjct: 1776 P---ERASESSSEEKDDYE-IFVKVKDTHEK--SKKNKNRDKGEKEKKRDSSLRSRSKRS 1829
Query: 1398 SNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRH 1457
+ S + R+ +R+RSS + S + RR RS S G + S+
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889
Query: 1458 SLSGSSPGMKDIPRTPSRGRSEC-DSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRER 1516
SP + R R RS D+ +A +TP RSRS +P + + R R
Sbjct: 1890 KRK-RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRS-HTPSRRRRSRSVGRRR 1947
Query: 1517 SGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQR 1576
S S+ +RTP +RSR+ S + S +P RS + S ++RTP
Sbjct: 1948 S---FSISPSRRSRTP-SRRSRTPS------RRSRTPSRRSRTPS-----RRSRTP---- 1988
Query: 1577 SRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636
SR +P +SR RR SP + R R + R+ RR
Sbjct: 1989 SRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFS------------RSPIRRK 2036
Query: 1637 RSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP--------RR 1688
RS SS +GR P E + A P P PP ++
Sbjct: 2037 RSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKK 2096
Query: 1689 RSSRSSPELTRKARLSRRSR-------SASSSPETRSRTPPRHRRSPSVSSPEP 1735
+ ELT K + +S+ + + PP + +S P+P
Sbjct: 2097 SGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKP 2150
Score = 62.4 bits (150), Expect = 6e-09
Identities = 93/322 (28%), Positives = 139/322 (43%), Gaps = 65/322 (20%)
Query: 715 SRTPQRRGRSGSSSERKN------KSRTSQRRSRSNSSP---EMKKSRISSRRSRSLSSP 765
S P+R S SSSE K+ K + + +S+ N + E +K R SS RSRS S
Sbjct: 1773 SSMPERA--SESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSK 1830
Query: 766 RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ 825
S+ KSR K+ S++ +SR R S+S S +
Sbjct: 1831 SSEHKSR--------------KRTSES--------------RSRARKRSSKSKSHRSQTR 1862
Query: 826 KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR--SCFESSPDPELKS 883
R+ SS S + ++ SP+ +S +R+ S ++ +S
Sbjct: 1863 SRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922
Query: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS-SSPSPSRVT 942
RTPSR S +S TP R+ SRS + ISP +RS + S S +PSR
Sbjct: 1923 RTPSRRS---------RSHTPSRRRRSRSVGRRRSFS--ISPSRRSRTPSRRSRTPSR-R 1970
Query: 943 SRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ 1002
SRT RRSR+ S S SR S +P + + + R+ S SISP +++
Sbjct: 1971 SRTPSRRSRTPSRRSRTPSR--------RSRTPSRRRRSRSVVRR-RSFSISPVRLRRSR 2021
Query: 1003 TPPGPSLSGSKSPCPQEKSKDS 1024
TP S+SP +++S+ S
Sbjct: 2022 TPLRRRF--SRSPIRRKRSRSS 2041
Score = 61.2 bits (147), Expect = 1e-08
Identities = 85/332 (25%), Positives = 121/332 (36%), Gaps = 40/332 (12%)
Query: 2450 PVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
P+P SDQ+ + +G + T +G S + +D+ P
Sbjct: 1682 PLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSG-----FSANIEDINEADLVRP 1736
Query: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
++ ++L A S S++S SS +S SS D E
Sbjct: 1737 LLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKV 1796
Query: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
K+ + KE R+ + R +RS SS S +S S S + S
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDS-----SLRSRSKRSKSSEHKSRKRTSESRSRARKRS 1851
Query: 2630 SSSSSSSSSSSSSSSS----SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685
S S S S + S S S SS S +K + K+ P +SR ++ S
Sbjct: 1852 SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSS 1911
Query: 2686 RDS-------------RSLSYSPVERRRP---------SPQPSPRDQQSSSSER-GSRRG 2722
RD+ RS S++P RRR S PS R + S R SRR
Sbjct: 1912 RDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRS 1971
Query: 2723 QRGDSRSPSHKRRRETPSPR---PMRHRSSRS 2751
+ RS + RR TPS R P R R SRS
Sbjct: 1972 RTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Score = 59.7 bits (143), Expect = 4e-08
Identities = 67/209 (32%), Positives = 82/209 (39%), Gaps = 10/209 (4%)
Query: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588
E RS + SS S S S + S S S SS S S + KR SP K
Sbjct: 1842 ESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKS 1901
Query: 2589 AVRE-----GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
R+ R T R R S S S + S S S S S S S S + S
Sbjct: 1902 RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPS 1961
Query: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP--RKPIDSLRDSRSLSYSPVERRRP 2701
S +PS P + S + P RRSR+P R+ S+ RS S SPV RR
Sbjct: 1962 RRSRTPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPSRRRRSRSVVRRRSFSISPVRLRRS 2020
Query: 2702 SPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
R +S + SR +RG RSP
Sbjct: 2021 RTPLRRRFSRSPIRRKRSRSSERG--RSP 2047
Score = 53.5 bits (127), Expect = 3e-06
Identities = 113/513 (22%), Positives = 193/513 (37%), Gaps = 87/513 (16%)
Query: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857
R S+ S P R S SSS + + +H S + G ++ +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 858 PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ- 916
+++S + + +S +S + ++R S S S S R +S + R+ SRS S
Sbjct: 1823 RSRSKRSKSSEHKSRKRTS-ESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSR 1881
Query: 917 -----PKVKAIISPRQRSHSGSSSPSPS---------RVTSRTTPRRSRSVSPCSNVESR 962
K K SP+ RS S S R SRT RRSRS +P SR
Sbjct: 1882 GRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSR 1941
Query: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGS-KSPCPQEKS 1021
+ R S S SP + + TP R+S + P +++TP S + S +S P +S
Sbjct: 1942 SVGR-RRSFSISPSRRSR--TPSRRSRT------PSRRSRTPSRRSRTPSRRSRTPSRRS 1992
Query: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS 1081
+ + +S + F +S ++L+ S +R+ S
Sbjct: 1993 RTPSRRR-----------RSRSVVRRRSFSISPVRLR------------RSRTPLRRRFS 2029
Query: 1082 ESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA---------SPMLKSGMS 1132
SP + +S++S +G RS +T+L + + +A P LK
Sbjct: 2030 RSPIRRKRSRSSERG---RSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPP 2086
Query: 1133 PEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPV 1192
P + S T++ L + + A+SKE + + + ++ F P
Sbjct: 2087 PTIEEKVAKKSGGATIEE---LTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPF 2143
Query: 1193 QDRPESSLVFKDTLR----TPPRER--------SGAGSSPETKEQNSA----LPTSSQDE 1236
+ + F + TPP+ + +GS KE +S +P E
Sbjct: 2144 KLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGE 2203
Query: 1237 ELMEVVEKSEEPAGQILSHLSSELKEMSTSNFE 1269
E +++ S+L SE ++ST+ E
Sbjct: 2204 E-------NKDDDNVFSSNLPSEPVDISTAMSE 2229
Score = 51.2 bits (121), Expect = 1e-05
Identities = 174/864 (20%), Positives = 283/864 (32%), Gaps = 126/864 (14%)
Query: 1983 RSRTSPVTRRRSRSRTS-PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKR 2041
RS SP+ R S + RS SP+ R S + R+ + +R
Sbjct: 1022 RSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMS---------AYERSMMSAYER 1072
Query: 2042 SRSRSPLAIRRR-----SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPAT 2096
S SP+A R RS + RS+ S A R S ++DRS + +
Sbjct: 1073 SMM-SPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADS 1131
Query: 2097 RNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSM 2156
S + T A + P+M P P + P M PL P
Sbjct: 1132 YTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEE---PPMTPPLPPEEPP----------- 1177
Query: 2157 MDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPS---------------MSA 2201
GP +P Q EN + + + + S+ PP S +SA
Sbjct: 1178 ---EGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSA 1234
Query: 2202 AGLAARMSQV------PAPVPLMSLRTAPAAN-----------------LASRIPAASAA 2238
+ + +S+ P P P S+ P + + S PA SA
Sbjct: 1235 SDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAE 1294
Query: 2239 AMNLASARTPAIPTAVNLADSRTP---AAAAAMNLASPRTAVAPSAVNLADPRTPTAPAV 2295
LAS TA R A+ + +L P A ++ +P AP
Sbjct: 1295 PTVLASEPPVMSETAETFDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPAMAAPES 1354
Query: 2296 NLAGARTPAALAAL---SLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNI 2352
+ +A+ L ++T + PS P+ P A P PV
Sbjct: 1355 SAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVTVPEPPVVAE---PDYVTIPVPVVS 1411
Query: 2353 AGSRTAAALAPA-SLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPP 2411
A + L PA S+ M + ++ V +S + + + P
Sbjct: 1412 ALEPSVPVLEPAVSVLQPSMIVSEPSVSVQESTVTVSEPAVTVSEQTQVIPTEVAIESTP 1471
Query: 2412 SAPSQSRMTSERAPSPSSRMGQ---APS---QSLLPPAQDQPRSP--VPSAFSDQSRCL- 2462
S M+S + G AP Q + + ++P + + F + +
Sbjct: 1472 MILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFYESEHGIN 1531
Query: 2463 --IAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA------------PGVPHSDVGE 2508
+ + + + A TS G+ +P PGV +D GE
Sbjct: 1532 IDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGE 1591
Query: 2509 PPASTG--AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS 2566
+STG A +P A + + +S+ S + S ++ + S+S S GS
Sbjct: 1592 TLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMVISTSPSGGS 1651
Query: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
++ + K + P+ V + EP P K ++ ++ S SS
Sbjct: 1652 EADIEGPLPAKDIHLDLPSNNNLVSKD-TEEPLPVKESDQTLAALLSPKESSGGEKEVPP 1710
Query: 2627 SSSSSSSSSSSSSSSSSSSSSS---PSPAKPGPQALPKPASPKKP--PPGERRSRSPRKP 2681
+ S S++ + + P K + A + P R RS P
Sbjct: 1711 PPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASP 1770
Query: 2682 IDSLRDSRSLSYSPVER------------RRPSPQPSPRDQQSSSSER-GSRRGQRGDSR 2728
+ S R+ S E+ S + RD+ +R S R + S+
Sbjct: 1771 VVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSK 1830
Query: 2729 SPSHKRRRETPSPRP-MRHRSSRS 2751
S HK R+ T R R RSS+S
Sbjct: 1831 SSEHKSRKRTSESRSRARKRSSKS 1854
Score = 45.4 bits (106), Expect = 8e-04
Identities = 90/387 (23%), Positives = 150/387 (38%), Gaps = 36/387 (9%)
Query: 922 IISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP-CSNVESRLLPRYSHSGSSSPDTKVK 980
I P S G + S V S R S S S + E + + +H S + K
Sbjct: 1752 IEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDK 1811
Query: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVK 1040
E ++ S ++ S S+S + SK +S S S +
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 1041 SSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSR 1100
S+ G S+ K + + SP HRS + + ++S S ++++ RSR
Sbjct: 1872 RSSRSRSKSRGRRSVS-KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSR 1930
Query: 1101 SSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLE 1160
S +P SRS R R FS SP +S +SR S S P+ S + +SR
Sbjct: 1931 SHTPSRRRRSRSVGR--RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1988
Query: 1161 TAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER----SGA 1216
+ S+ P + + S R++ FS PV+ R + + + R+P R + S
Sbjct: 1989 SRRSR----TPSRRRRSRSVVRRR-SFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSER 2043
Query: 1217 GSSP------------ETKEQNSA---------LPTSSQDEELMEVVEK-SEEPAGQILS 1254
G SP E + N+A LP + + + EK +++ G +
Sbjct: 2044 GRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIE 2103
Query: 1255 HLSSELKEMSTSNFESSPEVEERPAVS 1281
L+ + K+++ S E + +P VS
Sbjct: 2104 ELTEKCKQIAQSK-EDDDVIVNKPHVS 2129
Score = 42.0 bits (97), Expect = 0.008
Identities = 59/242 (24%), Positives = 91/242 (37%), Gaps = 27/242 (11%)
Query: 225 KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAA 284
K +KH+ K K+K K+K++K R + ++H + D S S SA A
Sbjct: 107 KSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVA 166
Query: 285 KTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKE 344
T G S + E A EP S + T +P++ K +
Sbjct: 167 LELPTRAFGPSET------NESPAVVLEPPVVSMEVSEPHILETLKPAT----KTAELSV 216
Query: 345 KSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL-SQEPVNPPSEASPTRDR 403
S + S E+S P+ T +L + +P P T L S EPV S
Sbjct: 217 VSTSVISEQSEQSVAVMPEPSMTKIL-DSFAAAPVPTTTLVLKSSEPVVTMSV------E 269
Query: 404 SPPKSPEKLPQSSSSESS------PPSP---QPTKVSRHASSSPESPKPAPAPGSHREIS 454
KS K +S+S E S PP +P++ +S +P P P+ + +
Sbjct: 270 YQMKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFP 329
Query: 455 SS 456
S
Sbjct: 330 ES 331
Score = 39.3 bits (90), Expect = 0.054
Identities = 71/324 (21%), Positives = 114/324 (35%), Gaps = 49/324 (15%)
Query: 152 DPQRRAREAKQPAPEP----PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRR 207
DP R + + P+P P+PY + S +P P + + RRS S
Sbjct: 947 DPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRI-APRPYRLAPRPLMLASRRSMMMSYAA 1005
Query: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSAD 267
ER S ++ E R SP + S ++ S R+ S A+
Sbjct: 1006 ERSMMSSYERSMMSYE---RSMMSPMAERSMMSAYERSMMSAY-------ERSMMSPMAE 1055
Query: 268 SASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETA 327
+ S RS SA ++ + +A RS R + S SS A
Sbjct: 1056 RSMMSAYERSMM-SAYERSMMSPMADRSMMSMGADR----SMMSSYSAADRSMMSSYSAA 1110
Query: 328 TKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLS 387
+ S Y D+ S S + + T E PL E P + P
Sbjct: 1111 DRSMMSSYT---ADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEE----PPTMPPLPPE 1163
Query: 388 QEPVNPPSEASPTRDRSPPKSPEKLP------QSSSSESSPPSPQPTKVSRHASSSPESP 441
+ P+ PP PP+ P + P + ++E++ P+ P+ S + S PE P
Sbjct: 1164 EPPMTPPL---------PPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPP 1214
Query: 442 -------KPAPAPGSHREISSSPT 458
+P+ P + +S P+
Sbjct: 1215 VSQSEISEPSAVPTDYSVSASDPS 1238
Score = 37.7 bits (86), Expect = 0.16
Identities = 70/286 (24%), Positives = 104/286 (36%), Gaps = 35/286 (12%)
Query: 178 SSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSK 237
S PT + KK KK + +++ ++E++K K K+ ESESK + H +
Sbjct: 94 SVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEK--KYKRQPEESESKTKSHDDGNIDLE 151
Query: 238 RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS--------SSDTSRSR-SRSAAAKTHT 288
S K + +R S + +S + S + S + T T
Sbjct: 152 SDSFLKFDSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKT 211
Query: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTS-----TQRPSSPETATKQPSSPYEDKDKDKK 343
L+ S S S + + A EP T P T + S P + +
Sbjct: 212 AELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQ 271
Query: 344 EKSATR--PSPSPERSSTG-PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPT 400
KS + S SPE S EPP L +P T +S E P+E P
Sbjct: 272 MKSVLKSVESTSPEPSKIMLVEPPVAKVL---------EPSETLVVSSE---TPTEVYPE 319
Query: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKV-SRHASSSPESPKPAP 445
S + P+SS+ E+ QP V S A SS P+ P
Sbjct: 320 PSTS---TTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELP 362
Score = 37.4 bits (85), Expect = 0.21
Identities = 72/316 (22%), Positives = 113/316 (35%), Gaps = 51/316 (16%)
Query: 170 PYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRS-----ESES 224
P + S + K KKKKKKK++ E R+ + SK K H ES+S
Sbjct: 99 PTDEIPTKKSKKHKKHKNKKKKKKKEK----EKKYKRQPEESESKTKSHDDGNIDLESDS 154
Query: 225 KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAA 284
+ P+ + + +PA S +T + +++A
Sbjct: 155 FLKFDSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAEL 214
Query: 285 KTHTTALAGRS--------PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE 336
+T++ P P+ + + A P TT + S P S Y+
Sbjct: 215 SVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTM---SVEYQ 271
Query: 337 DKDKDKKEKSATRPSPSPERSSTGPE----PPAPTPLLAERHGGS--PQPLATTP----- 385
K K +S T P PS P P+ T +++ P+P +T
Sbjct: 272 MKSVLKSVES-TSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPE 330
Query: 386 --------LSQEPVNPPSE---ASPTRDRSPPKSPEKLP---QSSSSESSPPSPQPTKVS 431
L ++PV+ PSE +S TR + P+ P+ Q SS S+ P P
Sbjct: 331 SSAIEALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPP--- 387
Query: 432 RHASSSPESPKPAPAP 447
A+S PE P P
Sbjct: 388 --ATSMPELQGPPVTP 401
Score = 35.4 bits (80), Expect = 0.78
Identities = 59/257 (22%), Positives = 82/257 (31%), Gaps = 59/257 (22%)
Query: 204 SPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS 263
SP ER S + RS + +R SP S R S + A +S + S
Sbjct: 1051 SPMAERSMMSAYE--RSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYS 1108
Query: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGR------------------SPSPASGRRGE 305
+ S SS T+ S AA ++T + P P
Sbjct: 1109 AADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMT 1168
Query: 306 GDAPFSEP----------------GTTSTQRPSSP-ETATKQPSSPYEDKDKDK------ 342
P EP T T+ PSSP E + QP P + +
Sbjct: 1169 PPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPT 1228
Query: 343 -------------KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
E + T P P PE S+ P + ++AE H P+ T +S+
Sbjct: 1229 DYSVSASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSE- 1287
Query: 390 PVNPPSEASPTRDRSPP 406
P A PT S P
Sbjct: 1288 --TPAMSAEPTVLASEP 1302
Score = 33.1 bits (74), Expect = 3.9
Identities = 46/238 (19%), Positives = 82/238 (34%), Gaps = 6/238 (2%)
Query: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRN 1335
E VS ++ QS+ S+ + PSM +P E +E++
Sbjct: 213 ELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQM 272
Query: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQS-TRSSGHSSSELSPDAVEKA 1394
L + +T + P LE +L + ++ T S+ + D E +
Sbjct: 273 KSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESS 332
Query: 1395 GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
+ + + PV PS SS + P+ LP+T + + S + G P
Sbjct: 333 AIEALRLPEQPV-----DVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPP 387
Query: 1455 SRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTP 1512
+ P + + P + P P + P P + + PEL +TP
Sbjct: 388 ATSMPELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTP 445
Score = 32.3 bits (72), Expect = 6.6
Identities = 53/266 (19%), Positives = 95/266 (35%), Gaps = 18/266 (6%)
Query: 2411 PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAF-----SDQSRCLIAQ 2465
PS ++S P S + + L PA V S S+QS ++ +
Sbjct: 176 PSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVAVMPE 235
Query: 2466 TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQ 2525
+ S ++ V TTT ++++ S + +++ +PS + ++
Sbjct: 236 PSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTS--PEPSKIMLVE 293
Query: 2526 PAKERRSSSSSS---SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582
P + S + SS + + S+S++ SS E LP QP V P
Sbjct: 294 PPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQP------VDVP 347
Query: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
+ ++ RP E + SS +S+ ++S +
Sbjct: 348 SEIADSSMT--RPQELPELPKTTALELQESSVASAMELPGPPATSMPELQGPPVTPVLEL 405
Query: 2643 SSSSSSPSPAKPGPQALPKPASPKKP 2668
S++P P PGP + P P P P
Sbjct: 406 PGPSATPVPELPGPLSTPVPELPGPP 431
Score = 32.0 bits (71), Expect = 8.6
Identities = 78/383 (20%), Positives = 129/383 (33%), Gaps = 53/383 (13%)
Query: 2164 IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA-----AGLAARMSQVPAPVPLM 2218
+P+ T + ++ A + + T + L ++ P +MS + L + S P P +M
Sbjct: 233 MPEPSMTKILDSFAAAPVPT--TTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKIM 290
Query: 2219 SLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVA 2278
L P A + P+ + + P+ D +A A+ L V
Sbjct: 291 -LVEPPVAKVLE--PSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVP 347
Query: 2279 PSAVNLADPRT---PTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPAS 2335
+ + R P P + + +A+ L G P A + P P P
Sbjct: 348 SEIADSSMTRPQELPELPKTTALELQESSVASAMELPG----PPATSMPELQGPPVTPV- 402
Query: 2336 ANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSG 2395
L GP S T P L++ P L G P +A + G
Sbjct: 403 LELPGP-------------SATPVPELPGPLSTP--VPELPGP-------PATAVPELPG 440
Query: 2396 RTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP---VP 2452
+ P+ ++ APS + P P + P L+ A + P P V
Sbjct: 441 PSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVA 500
Query: 2453 SAFSDQSRCLIAQTTPVAGSQSLSSG--AVATTTSSAGDHNGMLSVPAPGVPHS----DV 2506
++Q PV + G V T T G + + PG P + ++
Sbjct: 501 MELTEQPVTTTELEQPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALEL 560
Query: 2507 GEPPASTGAQQ----PSALAALQ 2525
P+ TG + PSA AL+
Sbjct: 561 PGQPSVTGVPELPGLPSATRALE 583
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 160 bits (404), Expect = 2e-38
Identities = 173/509 (33%), Positives = 235/509 (46%), Gaps = 80/509 (15%)
Query: 300 SGRRGEGDAPFS-EPGTTSTQRPSSPETA-TKQPSSPYE------DKDKDKKEKSATRPS 351
+G PF+ EP T T + TA T + Y+ +D + +T PS
Sbjct: 1589 AGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMVISTSPS 1648
Query: 352 PSPERSSTGPEPPAPTPL-------LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404
E GP P L L + P P+ + + + P E+S
Sbjct: 1649 GGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSPKESSGGEKEV 1708
Query: 405 PPKSPEKLPQSSSSES----------SPPSPQPTKVSRHASSSPESPKPAPAPGSHRE-- 452
PP E LP S S + P P+ + + E P A G R
Sbjct: 1709 PPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAA 1768
Query: 453 ---ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS-RS 508
+SS P + S K D + ++ + + + R + KR S RS
Sbjct: 1769 SPVVSSMPERASESSSEEKDD----YEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRS 1824
Query: 509 RSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPA 568
RS +RS+S++ R R+ + R R+R +R S+S +Q R RSRS RR RS
Sbjct: 1825 RS---KRSKSSEHKSRKRTSESRSRAR--KRSSKSKSHRSQTRSRSRSRRRRRS------ 1873
Query: 569 TRGRSRSRTPARRGRS---RSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS 625
RSRS++ RR S R R+P + RS+SR R+RS SR + R+RSRTP+RR S
Sbjct: 1874 --SRSRSKSRGRRSVSKEKRKRSP-KHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR-S 1929
Query: 626 RTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRT 685
R+ +P RRR RSRS RR RS S +P+RR SRTP+RR SRTP+RRS RT
Sbjct: 1930 RSHTPSRRR-RSRSVGRR--RSFSISPSRR----SRTPSRR----SRTPSRRS-----RT 1973
Query: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNS 745
P+R RSRTP R RSR+ RR SRTP RR RS S R++ S + R RS +
Sbjct: 1974 PSR----RSRTPSR---RSRTPSRR----SRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 746 SPEMKKSRISSRRSRSLSSPRSKAKSRLS 774
+ SR RR RS SS R ++ RL+
Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKRLT 2051
Score = 140 bits (353), Expect = 2e-32
Identities = 123/328 (37%), Positives = 169/328 (51%), Gaps = 51/328 (15%)
Query: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWS----------RSRNTQRRGRSRSARRGRSHS 564
R RSA S P+R S S ++ + +S+ + R + ++ S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 565 RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRR 624
RS + R +S S +R+ S SR+ AR+RS R ++RSR+ +RR R SR+ R +
Sbjct: 1823 RSRSKRSKS-SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRS--RSK 1879
Query: 625 SRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
SR R V + R RSP RS +SR R +R RS SR + R+RSRTP+RRS RS
Sbjct: 1880 SRGRRSVSKEKRKRSPKHRS-KSRER---KRKRSSSRDNRKTVRARSRTPSRRS---RSH 1932
Query: 685 TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN 744
TP+RR RSRS RR S S S SRTP RR R+ S +SRT RRSR+
Sbjct: 1933 TPSRRRRSRSVGRRRSFSISPS------RRSRTPSRRSRTPS-----RRSRTPSRRSRTP 1981
Query: 745 SSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQP 804
S ++SR SRRSR +P + +SR +RR SP ++S+TP RR
Sbjct: 1982 S----RRSRTPSRRSR---TPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRR-------- 2026
Query: 805 KAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
SR+P RR RS SS ++ ++P R
Sbjct: 2027 -RFSRSPIRRKRSRSS----ERGRSPKR 2049
Score = 137 bits (344), Expect = 2e-31
Identities = 246/1085 (22%), Positives = 385/1085 (35%), Gaps = 183/1085 (16%)
Query: 854 SITSPQANEQSVTPQRRSCFE----SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909
S+ SP A ++ RS S P + S + S S +P
Sbjct: 1023 SMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRS 1082
Query: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSH 969
S + + S RS S S + + S T RS + Y+
Sbjct: 1083 MMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTE 1142
Query: 970 SGSSSPDTKVKPET-PPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQS 1028
+ P +P T PP ++P P + P GP+L +S E + + V S
Sbjct: 1143 AYMVPPLPPEEPPTMPPLPPEEPPMTP-PLPPEEPPEGPALPTEQSALTAENTWPTEVPS 1201
Query: 1029 CPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS------- 1081
P S V PP VS ++ S D+ S P V S +
Sbjct: 1202 SPSEES----VSQPEPP------VSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEP 1251
Query: 1082 -------------ESPSLQSKSQTSPK-------GGRSRSSSPVTELASRSPIRQDRGEF 1121
ES + + + P+ S+ T LAS P+ + E
Sbjct: 1252 PPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAET 1311
Query: 1122 SAS----------------------PMLKSGMSPEQSRFQSDSSSYPTVDSNSL--LGQS 1157
S P+L + + +SS+ ++S+++ L S
Sbjct: 1312 FDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESS 1371
Query: 1158 RLETAESKEKMALPPQEDATASPP--RQKDKFS-PFPVQD---------RPESSLVFKDT 1205
+ ES L P PP + D + P PV P S++
Sbjct: 1372 TVTVLESSTVTVLEPSVVTVPEPPVVAEPDYVTIPVPVVSALEPSVPVLEPAVSVLQPSM 1431
Query: 1206 LRTPP----RERSGAGSSPET--KEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSE 1259
+ + P +E + S P EQ +PT E ++E S + SH+
Sbjct: 1432 IVSEPSVSVQESTVTVSEPAVTVSEQTQVIPTEVAIESTPMILESSI-----MSSHVMKG 1486
Query: 1260 LKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSN 1319
+ +S+ + +PE+ + +L + E P G + EH +
Sbjct: 1487 IN-LSSGDQNLAPEI------------GMQEIALHSGEEPHAEEHLKGDFYESEHGINID 1533
Query: 1320 SPLRENSFGSPLEFRNSGPLGT-------EMNTGFSSEVKEDLNGPFLNQLETDPSLDMK 1372
+ + +E GT E +SE K+ L+T P +
Sbjct: 1534 LNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQR------TVLDTYPGV--- 1584
Query: 1373 EQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL- 1431
S +G + S P A+E +++ I + + S ++ + + +
Sbjct: 1585 --SEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMV 1642
Query: 1432 ----PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPG----MKDIPRTPSRGRSECDSS 1483
P S G P PS ++L +K+ +T + S +SS
Sbjct: 1643 ISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSPKESS 1702
Query: 1484 PEPKALPQTPRPRSRSPSS-----------PELNNKCLTPQRERSGS----------ESS 1522
K +P P P+ P S +L L ER S S
Sbjct: 1703 GGEKEVP--PPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASD 1760
Query: 1523 VDQKTVARTP----LGQRSRSGSSQELD-------VKPSASPQERSESDSSPDSKAKTRT 1571
V + A +P + +R+ SS+E D VK + +++++ + + K +
Sbjct: 1761 VGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDS 1820
Query: 1572 PLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA 1631
LR RS+ S E S+ R S RSR+ R+ R++S R+
Sbjct: 1821 SLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRS-------------RS 1867
Query: 1632 LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE----PKTKSRTPPR 1687
RR S S SK RG + SP+H KSR +R SS + + +SRTP R
Sbjct: 1868 RRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 1688 RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747
R S +P R++R R RS S SP RSRTP R R+PS S P+ +SR+ RR
Sbjct: 1928 RSRSH-TPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR 1986
Query: 1748 ASSPRTKTTSRRGRSPS-PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
S R++T SRR RS S + R S R RR +T RR RS + SR +R RS
Sbjct: 1987 TPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Query: 1807 RSRVT 1811
R+T
Sbjct: 2047 PKRLT 2051
Score = 137 bits (344), Expect = 2e-31
Identities = 146/381 (38%), Positives = 184/381 (48%), Gaps = 57/381 (14%)
Query: 1648 SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS--------RTPPRRRSSRSSPELTR 1699
SP+ SS E PPK G ++ E ++ + R S R+ E
Sbjct: 1697 SPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPL 1756
Query: 1700 KARLSRRSRSA-----SSSPETRSRTPPRHRRSPS--VSSPEPAEKSRSSRRRRSASSPR 1752
A R RSA SS PE S + + V + EKS+ ++ R +
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK 1816
Query: 1753 TKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTR 1812
+ +S R RS K S R++T +R R R SS+S S R Q +RSRSR R
Sbjct: 1817 KRDSSLRSRSKRSK------SSEHKSRKRTSESRSRARKRSSKSKSHRSQ-TRSRSRSRR 1869
Query: 1813 RRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPAT 1872
RRR SRS ++ R+ S+ +R RS P R +SR R KRS SR + T
Sbjct: 1870 RRRS-----SRSRSKSRGRRSVSKEKRKRS---PKHRSKSRERKR----KRSSSRDNRKT 1917
Query: 1873 HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
R +RSRTP RRSRS T P RRRSRS V RRRS S SP R R+ SR
Sbjct: 1918 VR-ARSRTP---SRRSRSHT-PSRRRRSRS---VGRRRSFS-ISPSRRSRTPSRRSRTPS 1968
Query: 1933 RRSR-----SRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTS 1987
RRSR SRTP+ R R+ SR RR RSR+ V RRRS S SP+ RRSR+
Sbjct: 1969 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS--VVRRRSFS-ISPVRLRRSRT--- 2022
Query: 1988 PVTRRRSRSRTSPVTRRRSRS 2008
P+ RR SR SP+ R+RSRS
Sbjct: 2023 PLRRRFSR---SPIRRKRSRS 2040
Score = 129 bits (323), Expect = 5e-29
Identities = 238/934 (25%), Positives = 362/934 (38%), Gaps = 148/934 (15%)
Query: 1120 EFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179
E +SP +S PE QS+ S V ++ + S S+ + +P
Sbjct: 1198 EVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEP------ 1251
Query: 1180 PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPT--SSQDEE 1237
PP + + PV ES++V ++ P ER ET SA PT +S+
Sbjct: 1252 PPEPESSITLTPV----ESAVVAEEHEVVP--ERPVTCMVSETPAM-SAEPTVLASEPPV 1304
Query: 1238 LMEVVEK--SEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEA 1295
+ E E S +G + S +S+ L + + + + E PA++ +S + A LE+
Sbjct: 1305 MSETAETFDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPAMAAP--ESSAMAVLES 1362
Query: 1296 VEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDL 1355
V + SS S L S + + P + + + E +
Sbjct: 1363 SAVTVLESSTVTVLESSTVTVLEPSVV---TVPEPPVVAEPDYVTIPVPVVSALEPSVPV 1419
Query: 1356 NGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPS 1415
P ++ L+ PS+ + E S S E + E A S Q+ P A+ TP
Sbjct: 1420 LEPAVSVLQ--PSMIVSEPSV-----SVQESTVTVSEPAVTVSEQTQVIPTEVAIESTPM 1472
Query: 1416 RERSSSASSPEMKDGLPRTPSRRS------------RSGSSPGLRD---GSGTPSRHSLS 1460
SS SS MK G+ + ++ SG P + G S H ++
Sbjct: 1473 ILESSIMSSHVMK-GINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFYESEHGIN 1531
Query: 1461 ----------------------GSSP-----GMKDIPRTPSRGRSECDSSPEPKALPQTP 1493
G+SP K +P + ++ R+ D+ P + +
Sbjct: 1532 IDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYP---GVSEAD 1588
Query: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQR-----SRSGSSQELDVK 1548
+ S + P + + +G+ ++ T + L + S + E D+
Sbjct: 1589 AGETLSSTGP------FALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMV 1642
Query: 1549 PSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
S SP SE+D AK ++ S + L + + + D+
Sbjct: 1643 ISTSPSGGSEADIEGPLPAKD-----------IHLDLPSNNNLVSKDTEEPLPVKESDQT 1691
Query: 1609 RAA---PRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665
AA P+ SG + P P LP G + E + + PK
Sbjct: 1692 LAALLSPKESSGGEKEVPP--PPKETLP--------DSGFSANIEDINEADLVRPLLPKD 1741
Query: 1666 RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR 1725
R+ E + R RS+ S + R S S E + H
Sbjct: 1742 MERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHE 1801
Query: 1726 RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTT 1785
+S + + EK + + S R+K++ + R + + R R RS + T
Sbjct: 1802 KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT 1861
Query: 1786 RRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP 1845
R R RS + +SR R +SR R V++ +R RSP + SR R+R
Sbjct: 1862 RSRSRSRRRRRSSRSRSKSRGRRSVSKEKR------KRSPKHRSKSRERKRKRSSSRDNR 1915
Query: 1846 PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRS---RS 1902
T R RSR+ P +RSRS +P+ RRSRS + RRRS S SP R R+ RS
Sbjct: 1916 KTVRARSRT-----PSRRSRSH-TPSRRRRSRS----VGRRRSFS-ISPSRRSRTPSRRS 1964
Query: 1903 RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
RT R R+ SR S R RSRTP RSRTP+ RRRSRS V RRRS S
Sbjct: 1965 RTPSRRSRTPSRRSRTPSR--RSRTP-----SRRSRTPSRRRRSRS----VVRRRSFS-I 2012
Query: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRS 1996
PV RRSR +P+ RR SR SP+ R+RSRS
Sbjct: 2013 SPVRLRRSR---TPLRRRFSR---SPIRRKRSRS 2040
Score = 128 bits (321), Expect = 9e-29
Identities = 152/456 (33%), Positives = 201/456 (44%), Gaps = 70/456 (15%)
Query: 1648 SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
SP G S + P K S ++ K P + S ++ L S
Sbjct: 1646 SPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALL--------S 1697
Query: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK- 1766
SS E PP+ S S + + + R + TS R P
Sbjct: 1698 PKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLL 1757
Query: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQS-----------TSRRRQRSRSRSRVTRRRR 1815
+ R RS + + R S S + T + +++++R + + ++
Sbjct: 1758 ASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKK 1817
Query: 1816 GGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR 1875
S SRS R +SS SR+R SR+ +RKRS S RSRSR S R
Sbjct: 1818 RDSSLRSRSK-RSKSSEHKSRKRTSESRS--RARKRSSKSKSHRSQTRSRSR-SRRRRRS 1873
Query: 1876 SRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRR---RSRSRTPPVTR 1932
SRSR S+ R R S R+RS S +R R R R+S R R+RSRTP
Sbjct: 1874 SRSR----SKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPS--- 1926
Query: 1933 RRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRR 1992
RRSRS TP+ RRRSRS V RRRS S +P RRSR+ P R R+ SR S R
Sbjct: 1927 RRSRSHTPSRRRRSRS----VGRRRSFSISPS---RRSRT---PSRRSRTPSRRSRTPSR 1976
Query: 1993 RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRR 2052
RSR+ P R R+ SR RSRTP + RRRSRS + R+RS S SP+ +R
Sbjct: 1977 RSRT---PSRRSRTPSR---------RSRTP-SRRRRSRS----VVRRRSFSISPVRLR- 2018
Query: 2053 RSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRS 2088
RSRTP +R +RSP IRR+ + S RS
Sbjct: 2019 --RSRTPL----RRRFSRSP--IRRKRSRSSERGRS 2046
Score = 127 bits (320), Expect = 1e-28
Identities = 121/408 (29%), Positives = 177/408 (43%), Gaps = 55/408 (13%)
Query: 523 GRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRG 582
GR RS S P+R S S + ++ + +H +S + R + +R
Sbjct: 1762 GRDRSAASPVVSSMPERA--SESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 583 RSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPAR 642
S R RS+ + +SR RT R R+R R+ + R+++ R RSR R R
Sbjct: 1820 SS-----LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR---R 1871
Query: 643 RSGRSRSRTPARRGRS---RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRR 699
RS RSRS++ RR S R R+P R +SR R R S R +T R+RSRTP R
Sbjct: 1872 RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV----RARSRTPSR 1927
Query: 700 GRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRS 759
RS S TP RR RS S R++ S + RRSR+ S ++SR SRRS
Sbjct: 1928 ------------RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPS----RRSRTPSRRS 1971
Query: 760 RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSS 819
R+ S RS+ SR S P ++S+TP RR RS S + P R R S
Sbjct: 1972 RT-PSRRSRTPSR---------RSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSR 2021
Query: 820 SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP 879
+P ++ S++P R+ S SS + +P R + Q E + C
Sbjct: 2022 TPLRRRFSRSPIRRKRSRSSE----RGRSPKRLTDLDKAQLLEIAKANAAAMC------- 2070
Query: 880 ELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQ 927
K+ P + + PP ++ + + K K I ++
Sbjct: 2071 -AKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKE 2117
Score = 109 bits (272), Expect = 4e-23
Identities = 99/252 (39%), Positives = 126/252 (50%), Gaps = 18/252 (7%)
Query: 1884 SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTR 1943
S RSRS+ S S +SR RTS +R R+R R+S RS++R +R RSR R ++R
Sbjct: 1820 SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR----SRSRSRRRRRSSR 1875
Query: 1944 RRSRSRTPPVTRRRSRSRTP---PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
RS+SR + R R+P +R R R R+S R++ S RRSRS T P
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHT-P 1934
Query: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP- 2059
RRRSRS V RRRS S P+ R R+ SR P +RSR+ S + RSRTP
Sbjct: 1935 SRRRRSRS----VGRRRSFS-ISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS 1989
Query: 2060 RTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119
R +R RS +RRRS S S RS T P R S S P+ SR S R
Sbjct: 1990 RRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT-PLRRRFSRS---PIRRKRSRSSERGR 2045
Query: 2120 PSMSPTPLDRCR 2131
T LD+ +
Sbjct: 2046 SPKRLTDLDKAQ 2057
Score = 102 bits (254), Expect = 5e-21
Identities = 86/280 (30%), Positives = 137/280 (48%), Gaps = 32/280 (11%)
Query: 664 ARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGR 723
+++ ++R + + S R+ ++R +S R+ S SRS R+ S S++ + + R
Sbjct: 1803 SKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR 1862
Query: 724 SGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783
S S S R+ +S S+ +SR S +K + S + RSK++ R R S +
Sbjct: 1863 SRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKH-------RSKSRERKRKRSSSRDNR 1915
Query: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK 843
+ +S+TP RRSRS + + +SR+ RR S SP ++S+TPSR+S + P
Sbjct: 1916 KTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP--SRRSRTPSRRSRT-----PS 1968
Query: 844 VKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRV-KSS 902
+S TP R+ S + +S TP RRS +P +SR+ R SP R+ +S
Sbjct: 1969 RRSRTPSRR----SRTPSRRSRTPSRRS---RTPSRRRRSRSVVRRRSFSISPVRLRRSR 2021
Query: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVT 942
TP R+ SRS R+RS S SP R+T
Sbjct: 2022 TPLRRRFSRSP----------IRRKRSRSSERGRSPKRLT 2051
Score = 95.9 bits (237), Expect = 5e-19
Identities = 102/332 (30%), Positives = 141/332 (42%), Gaps = 29/332 (8%)
Query: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTS-PVSRRRSRSRTSVTRRRSRSRASPVSRR 1921
R RS ASP + S + V +S+ + R + S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 1922 RSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRR 1981
RSRS+ + +SR RT +R R+R R+ RS++R+ +RRR RS S R +
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRS---RSK 1879
Query: 1982 SRSRTSPVTRRRSRS-RTSPVTRRRSRSRTSPVTRR---RSRSRTPPAIRRRSRSRTPLL 2037
SR R S +R RS + +R R R R+S R R+RSRTP RRSRS TP
Sbjct: 1880 SRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP---SRRSRSHTP-S 1935
Query: 2038 PRKRSRS---RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPP 2094
R+RSRS R +I RSRTP S P+ R R+ S S SR + P
Sbjct: 1936 RRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1995
Query: 2095 ATRNHSGS-------RTPPVALNSSRMSCFSRPSMSP------TPLDRCRSPGMLEPLGS 2141
+ R S S PV L SR R S SP +R RSP L L
Sbjct: 1996 SRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDK 2055
Query: 2142 SRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVP 2173
++ + + + +M G +P + + + P
Sbjct: 2056 AQL-LEIAKANAAAMCAKAGVPLPPNLKPAPP 2086
Score = 88.2 bits (217), Expect = 1e-16
Identities = 97/319 (30%), Positives = 137/319 (42%), Gaps = 36/319 (11%)
Query: 713 SHSRTPQRRGRSGSSSERKNKS--RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
+H ++ + + R E+K S R+ +RS+S+ K++ S R+R S SK+K
Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS---SKSK 1855
Query: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
S S RS S S RR RS S+ K++ R + + SP + KS+
Sbjct: 1856 SHRSQTRSRSRSR-----------RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRER 1904
Query: 831 SRQSHSSSSPHPKV--KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR 888
R+ SS V +S TP R+ +P +S + RR F S P +SRTPSR
Sbjct: 1905 KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSIS--PSRRSRTPSR 1962
Query: 889 HSCSGSSPPRVKSSTPPRQS--PSRSSSPQPKVKAIISPRQRSHS----GSSSPSPSRV- 941
S P +S TP R+S PSR S + S R+RS S S S SP R+
Sbjct: 1963 R----SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLR 2018
Query: 942 TSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKA 1001
SRT RR S SP SR S SP + + + + KA
Sbjct: 2019 RSRTPLRRRFSRSPIRRKRSR-----SSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKA 2073
Query: 1002 QTPPGPSLSGSKSPCPQEK 1020
P P+L + P +EK
Sbjct: 2074 GVPLPPNLKPAPPPTIEEK 2092
Score = 87.0 bits (214), Expect = 2e-16
Identities = 91/416 (21%), Positives = 167/416 (40%), Gaps = 46/416 (11%)
Query: 83 EEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETH---QLAELNE---------K 130
E ++E T +L K+ + G KE P + + ++ + ++NE K
Sbjct: 1681 EPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPK 1740
Query: 131 KNERLRAA-FGI------SDSYVDGSSFDP--QRRAREAKQPAPEPPKPYSLVRESSSSR 181
ERL + GI SD D S+ P A + + E Y + + +
Sbjct: 1741 DMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTH 1800
Query: 182 SPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESES----KKRKHRSPTPKSK 237
+ K K + K + +R S R +R KSS+ K + SES +KR +S + +S+
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ 1860
Query: 238 RKSKDKKRKRSRSTTPAPKSR-------------RAHRSTSADSASSSDTSRSRSRSAAA 284
+S+ + R+R RS+ KSR HRS S + +SR ++ A
Sbjct: 1861 TRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRA 1920
Query: 285 KTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKE 344
++ T + RS +P+ RR + ++R +P ++ PS + ++
Sbjct: 1921 RSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR--RSRTPSRRS 1978
Query: 345 KSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL----ATTPLSQEPVNPPSEASPT 400
++ +R S +P R S P + + R S P+ + TPL + P +
Sbjct: 1979 RTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRS 2038
Query: 401 RDRSPPKSPEKLPQSSSSE--SSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
R +SP++L ++ + ++ P + KPAP P +++
Sbjct: 2039 RSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVA 2094
Score = 86.7 bits (213), Expect = 3e-16
Identities = 245/1014 (24%), Positives = 384/1014 (37%), Gaps = 216/1014 (21%)
Query: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH 841
SSP + SQ P S+S S+P A P S S+S P S S + + P
Sbjct: 1201 SSPSEESVSQPEPPVSQSEISEPSA---VPTDYSVSASDP-----SVLVSEAAVTVPEPP 1252
Query: 842 PKVKSG---TPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898
P+ +S TP + A E V P+R P + S TP+ S+ P
Sbjct: 1253 PEPESSITLTPVESAVV----AEEHEVVPER-------PVTCMVSETPAM-----SAEPT 1296
Query: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV----- 953
V +S PP S + + S R H S + V + TTP + S+
Sbjct: 1297 VLASEPPVMSET--------AETFDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPA 1348
Query: 954 --SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ----TPPGP 1007
+P S+ + L SS T ++ T S P P V A+ T P P
Sbjct: 1349 MAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVTVPEPPVVAEPDYVTIPVP 1408
Query: 1008 SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH 1067
+S + P + S++Q V+ ST ++ + Q+Q P
Sbjct: 1409 VVSALEPSVPVLEPAVSVLQPSMIVSEPSVSVQESTVT----VSEPAVTVSEQTQVIPTE 1464
Query: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRS---PIRQD--RGEFS 1122
+ S+P + +S S + S + E+A S P ++ +G+F
Sbjct: 1465 VAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFY 1524
Query: 1123 ASPMLKSGMSPE---QSRFQSDSSSYPTVDSNSL-----LGQSR-LETAESKEKMALPPQ 1173
S + G++ + + + + TV + +G+ + L T+E+K++ L
Sbjct: 1525 ES---EHGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTY 1581
Query: 1174 EDAT-ASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTS 1232
+ A PF ++ P+++ K E + A + + + L +
Sbjct: 1582 PGVSEADAGETLSSTGPFALE--PDATGTSKGI------EFTTASTLSLVNKYDVDLSLT 1633
Query: 1233 SQDEELMEVVEKSEEPAGQILSHLSSELK------EMSTSNFESSPEVEERPAVSLTLDQ 1286
+QD E V+ S P+G + + L ++ ++N S + EE L
Sbjct: 1634 TQDTEHDMVI--STSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEE------PLPV 1685
Query: 1287 SQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTG 1346
+S +L A+ P SS G P KE T ++G
Sbjct: 1686 KESDQTLAALLSPK-ESSGGEKEVPPPPKE------------------------TLPDSG 1720
Query: 1347 FSSEVKE----DLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSI 1402
FS+ +++ DL P L + DM+ ++ +G L+ D + ++S
Sbjct: 1721 FSANIEDINEADLVRPLLPK-------DMERLTSLRAGIEGPLLASD------VGRDRSA 1767
Query: 1403 SSPVLDAVPRTPSRERSSSASSPE---------MKDGLPRTPSRRSRSGSSPGLRDGSGT 1453
+SPV+ ++P ER+S +SS E +KD ++ ++R + S
Sbjct: 1768 ASPVVSSMP-----ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 1454 PSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQ 1513
SR S SS + SR R+ SS QT R RSRS +
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT-RSRSRS-------------R 1868
Query: 1514 RERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPL 1573
R R S S K+ R + + R S + + S D+ +A++RTP
Sbjct: 1869 RRRRSSRSR--SKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPS 1926
Query: 1574 RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALP 1633
R+ S+S RR RS R+ R +S S SP ++ P
Sbjct: 1927 RR-----------SRSHTPSRRRRS----------RSVGRRRSFS-ISPSRRSRTP---S 1961
Query: 1634 RRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS 1693
RRSR+ S + R PS +SRT R SR+ P +SRTP RRR SRS
Sbjct: 1962 RRSRT-PSRRSRTPS--------------RRSRTPSRRSRT---PSRRSRTPSRRRRSRS 2003
Query: 1694 SPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747
+ RRS S S RSRTP R R S SP ++SRSS R RS
Sbjct: 2004 V--------VRRRSFSISPVRLRRSRTPLRRRFS---RSPIRRKRSRSSERGRS 2046
Score = 62.4 bits (150), Expect = 6e-09
Identities = 126/534 (23%), Positives = 195/534 (36%), Gaps = 79/534 (14%)
Query: 1222 TKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKE-MSTSNFESSPE-VEERPA 1279
+K+ LP D+ L ++ E G+ + KE + S F ++ E + E
Sbjct: 1676 SKDTEEPLPVKESDQTLAALLSPKESSGGE--KEVPPPPKETLPDSGFSANIEDINEADL 1733
Query: 1280 VSLTLDQSQSQ-ASLEA-VEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSG 1337
V L + + SL A +E P +AS G R+ S SP+ +S
Sbjct: 1734 VRPLLPKDMERLTSLRAGIEGPLLASDVG----------------RDRSAASPVV--SSM 1775
Query: 1338 PLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMS 1397
P E + SSE K+D F+ +T K+ R G + ++ S
Sbjct: 1776 P---ERASESSSEEKDDYE-IFVKVKDTHEK--SKKNKNRDKGEKEKKRDSSLRSRSKRS 1829
Query: 1398 SNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRH 1457
+ S + R+ +R+RSS + S + RR RS S G + S+
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889
Query: 1458 SLSGSSPGMKDIPRTPSRGRSEC-DSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRER 1516
SP + R R RS D+ +A +TP RSRS +P + + R R
Sbjct: 1890 KRK-RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRS-HTPSRRRRSRSVGRRR 1947
Query: 1517 SGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQR 1576
S S+ +RTP +RSR+ S + S +P RS + S ++RTP
Sbjct: 1948 S---FSISPSRRSRTP-SRRSRTPS------RRSRTPSRRSRTPS-----RRSRTP---- 1988
Query: 1577 SRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636
SR +P +SR RR SP + R R + R+ RR
Sbjct: 1989 SRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFS------------RSPIRRK 2036
Query: 1637 RSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP--------RR 1688
RS SS +GR P E + A P P PP ++
Sbjct: 2037 RSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKK 2096
Query: 1689 RSSRSSPELTRKARLSRRSR-------SASSSPETRSRTPPRHRRSPSVSSPEP 1735
+ ELT K + +S+ + + PP + +S P+P
Sbjct: 2097 SGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKP 2150
Score = 62.4 bits (150), Expect = 6e-09
Identities = 93/322 (28%), Positives = 139/322 (43%), Gaps = 65/322 (20%)
Query: 715 SRTPQRRGRSGSSSERKN------KSRTSQRRSRSNSSP---EMKKSRISSRRSRSLSSP 765
S P+R S SSSE K+ K + + +S+ N + E +K R SS RSRS S
Sbjct: 1773 SSMPERA--SESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSK 1830
Query: 766 RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ 825
S+ KSR K+ S++ +SR R S+S S +
Sbjct: 1831 SSEHKSR--------------KRTSES--------------RSRARKRSSKSKSHRSQTR 1862
Query: 826 KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR--SCFESSPDPELKS 883
R+ SS S + ++ SP+ +S +R+ S ++ +S
Sbjct: 1863 SRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922
Query: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS-SSPSPSRVT 942
RTPSR S +S TP R+ SRS + ISP +RS + S S +PSR
Sbjct: 1923 RTPSRRS---------RSHTPSRRRRSRSVGRRRSFS--ISPSRRSRTPSRRSRTPSR-R 1970
Query: 943 SRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ 1002
SRT RRSR+ S S SR S +P + + + R+ S SISP +++
Sbjct: 1971 SRTPSRRSRTPSRRSRTPSR--------RSRTPSRRRRSRSVVRR-RSFSISPVRLRRSR 2021
Query: 1003 TPPGPSLSGSKSPCPQEKSKDS 1024
TP S+SP +++S+ S
Sbjct: 2022 TPLRRRF--SRSPIRRKRSRSS 2041
Score = 61.2 bits (147), Expect = 1e-08
Identities = 85/332 (25%), Positives = 121/332 (36%), Gaps = 40/332 (12%)
Query: 2450 PVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
P+P SDQ+ + +G + T +G S + +D+ P
Sbjct: 1682 PLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSG-----FSANIEDINEADLVRP 1736
Query: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
++ ++L A S S++S SS +S SS D E
Sbjct: 1737 LLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKV 1796
Query: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
K+ + KE R+ + R +RS SS S +S S S + S
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDS-----SLRSRSKRSKSSEHKSRKRTSESRSRARKRS 1851
Query: 2630 SSSSSSSSSSSSSSSS----SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685
S S S S + S S S SS S +K + K+ P +SR ++ S
Sbjct: 1852 SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSS 1911
Query: 2686 RDS-------------RSLSYSPVERRRP---------SPQPSPRDQQSSSSER-GSRRG 2722
RD+ RS S++P RRR S PS R + S R SRR
Sbjct: 1912 RDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRS 1971
Query: 2723 QRGDSRSPSHKRRRETPSPR---PMRHRSSRS 2751
+ RS + RR TPS R P R R SRS
Sbjct: 1972 RTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Score = 59.7 bits (143), Expect = 4e-08
Identities = 67/209 (32%), Positives = 82/209 (39%), Gaps = 10/209 (4%)
Query: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588
E RS + SS S S S + S S S SS S S + KR SP K
Sbjct: 1842 ESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKS 1901
Query: 2589 AVRE-----GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
R+ R T R R S S S + S S S S S S S S + S
Sbjct: 1902 RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPS 1961
Query: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP--RKPIDSLRDSRSLSYSPVERRRP 2701
S +PS P + S + P RRSR+P R+ S+ RS S SPV RR
Sbjct: 1962 RRSRTPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPSRRRRSRSVVRRRSFSISPVRLRRS 2020
Query: 2702 SPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
R +S + SR +RG RSP
Sbjct: 2021 RTPLRRRFSRSPIRRKRSRSSERG--RSP 2047
Score = 53.1 bits (126), Expect = 4e-06
Identities = 102/457 (22%), Positives = 163/457 (35%), Gaps = 112/457 (24%)
Query: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857
R S+ S P R S SSS + + +H S + G ++ +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 858 PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ- 916
+++S + + +S +S + ++R S S S S R +S + R+ SRS S
Sbjct: 1823 RSRSKRSKSSEHKSRKRTS-ESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSR 1881
Query: 917 -----PKVKAIISPRQRSHSGSSSPSPS---------RVTSRTTPRRSRSVSPCSNVESR 962
K K SP+ RS S S R SRT RRSRS +P SR
Sbjct: 1882 GRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSR 1941
Query: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK 1022
+ R S S SP + + TP R+S + P +++TP S + S+
Sbjct: 1942 SVGR-RRSFSISPSRRSR--TPSRRSRT------PSRRSRTPSRRSRTPSR--------- 1983
Query: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSE 1082
+S TP S +P R + S R+S S
Sbjct: 1984 -----------------RSRTPSRRS--------------RTPSRRRRSRSVVRRRSFSI 2012
Query: 1083 SPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDS 1142
SP +S+T P+ SRSPIR+ R S + G SP++
Sbjct: 2013 SPVRLRRSRT-----------PLRRRFSRSPIRRKRSRSS-----ERGRSPKR------- 2049
Query: 1143 SSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVF 1202
+D LL ++ A K +P + +PP
Sbjct: 2050 --LTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPP--------------------- 2086
Query: 1203 KDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELM 1239
T+ ++SG + E E+ + S +D++++
Sbjct: 2087 -PTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVI 2122
Score = 51.2 bits (121), Expect = 1e-05
Identities = 174/864 (20%), Positives = 283/864 (32%), Gaps = 126/864 (14%)
Query: 1983 RSRTSPVTRRRSRSRTS-PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKR 2041
RS SP+ R S + RS SP+ R S + R+ + +R
Sbjct: 1022 RSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMS---------AYERSMMSAYER 1072
Query: 2042 SRSRSPLAIRRR-----SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPAT 2096
S SP+A R RS + RS+ S A R S ++DRS + +
Sbjct: 1073 SMM-SPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADS 1131
Query: 2097 RNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSM 2156
S + T A + P+M P P + P M PL P
Sbjct: 1132 YTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEE---PPMTPPLPPEEPP----------- 1177
Query: 2157 MDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPS---------------MSA 2201
GP +P Q EN + + + + S+ PP S +SA
Sbjct: 1178 ---EGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSA 1234
Query: 2202 AGLAARMSQV------PAPVPLMSLRTAPAAN-----------------LASRIPAASAA 2238
+ + +S+ P P P S+ P + + S PA SA
Sbjct: 1235 SDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAE 1294
Query: 2239 AMNLASARTPAIPTAVNLADSRTP---AAAAAMNLASPRTAVAPSAVNLADPRTPTAPAV 2295
LAS TA R A+ + +L P A ++ +P AP
Sbjct: 1295 PTVLASEPPVMSETAETFDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPAMAAPES 1354
Query: 2296 NLAGARTPAALAAL---SLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNI 2352
+ +A+ L ++T + PS P+ P A P PV
Sbjct: 1355 SAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVTVPEPPVVAE---PDYVTIPVPVVS 1411
Query: 2353 AGSRTAAALAPA-SLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPP 2411
A + L PA S+ M + ++ V +S + + + P
Sbjct: 1412 ALEPSVPVLEPAVSVLQPSMIVSEPSVSVQESTVTVSEPAVTVSEQTQVIPTEVAIESTP 1471
Query: 2412 SAPSQSRMTSERAPSPSSRMGQ---APS---QSLLPPAQDQPRSP--VPSAFSDQSRCL- 2462
S M+S + G AP Q + + ++P + + F + +
Sbjct: 1472 MILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFYESEHGIN 1531
Query: 2463 --IAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA------------PGVPHSDVGE 2508
+ + + + A TS G+ +P PGV +D GE
Sbjct: 1532 IDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGE 1591
Query: 2509 PPASTG--AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS 2566
+STG A +P A + + +S+ S + S ++ + S+S S GS
Sbjct: 1592 TLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMVISTSPSGGS 1651
Query: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
++ + K + P+ V + EP P K ++ ++ S SS
Sbjct: 1652 EADIEGPLPAKDIHLDLPSNNNLVSKD-TEEPLPVKESDQTLAALLSPKESSGGEKEVPP 1710
Query: 2627 SSSSSSSSSSSSSSSSSSSSSS---PSPAKPGPQALPKPASPKKP--PPGERRSRSPRKP 2681
+ S S++ + + P K + A + P R RS P
Sbjct: 1711 PPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASP 1770
Query: 2682 IDSLRDSRSLSYSPVER------------RRPSPQPSPRDQQSSSSER-GSRRGQRGDSR 2728
+ S R+ S E+ S + RD+ +R S R + S+
Sbjct: 1771 VVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSK 1830
Query: 2729 SPSHKRRRETPSPRP-MRHRSSRS 2751
S HK R+ T R R RSS+S
Sbjct: 1831 SSEHKSRKRTSESRSRARKRSSKS 1854
Score = 45.4 bits (106), Expect = 8e-04
Identities = 90/387 (23%), Positives = 150/387 (38%), Gaps = 36/387 (9%)
Query: 922 IISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP-CSNVESRLLPRYSHSGSSSPDTKVK 980
I P S G + S V S R S S S + E + + +H S + K
Sbjct: 1752 IEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDK 1811
Query: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVK 1040
E ++ S ++ S S+S + SK +S S S +
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 1041 SSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSR 1100
S+ G S+ K + + SP HRS + + ++S S ++++ RSR
Sbjct: 1872 RSSRSRSKSRGRRSVS-KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSR 1930
Query: 1101 SSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLE 1160
S +P SRS R R FS SP +S +SR S S P+ S + +SR
Sbjct: 1931 SHTPSRRRRSRSVGR--RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1988
Query: 1161 TAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER----SGA 1216
+ S+ P + + S R++ FS PV+ R + + + R+P R + S
Sbjct: 1989 SRRSR----TPSRRRRSRSVVRRR-SFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSER 2043
Query: 1217 GSSP------------ETKEQNSA---------LPTSSQDEELMEVVEK-SEEPAGQILS 1254
G SP E + N+A LP + + + EK +++ G +
Sbjct: 2044 GRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIE 2103
Query: 1255 HLSSELKEMSTSNFESSPEVEERPAVS 1281
L+ + K+++ S E + +P VS
Sbjct: 2104 ELTEKCKQIAQSK-EDDDVIVNKPHVS 2129
Score = 42.0 bits (97), Expect = 0.008
Identities = 59/242 (24%), Positives = 91/242 (37%), Gaps = 27/242 (11%)
Query: 225 KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAA 284
K +KH+ K K+K K+K++K R + ++H + D S S SA A
Sbjct: 107 KSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVA 166
Query: 285 KTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKE 344
T G S + E A EP S + T +P++ K +
Sbjct: 167 LELPTRAFGPSET------NESPAVVLEPPVVSMEVSEPHILETLKPAT----KTAELSV 216
Query: 345 KSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL-SQEPVNPPSEASPTRDR 403
S + S E+S P+ T +L + +P P T L S EPV S
Sbjct: 217 VSTSVISEQSEQSVAVMPEPSMTKIL-DSFAAAPVPTTTLVLKSSEPVVTMSV------E 269
Query: 404 SPPKSPEKLPQSSSSESS------PPSP---QPTKVSRHASSSPESPKPAPAPGSHREIS 454
KS K +S+S E S PP +P++ +S +P P P+ + +
Sbjct: 270 YQMKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFP 329
Query: 455 SS 456
S
Sbjct: 330 ES 331
Score = 39.3 bits (90), Expect = 0.054
Identities = 71/324 (21%), Positives = 114/324 (35%), Gaps = 49/324 (15%)
Query: 152 DPQRRAREAKQPAPEP----PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRR 207
DP R + + P+P P+PY + S +P P + + RRS S
Sbjct: 947 DPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRI-APRPYRLAPRPLMLASRRSMMMSYAA 1005
Query: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSAD 267
ER S ++ E R SP + S ++ S R+ S A+
Sbjct: 1006 ERSMMSSYERSMMSYE---RSMMSPMAERSMMSAYERSMMSAY-------ERSMMSPMAE 1055
Query: 268 SASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETA 327
+ S RS SA ++ + +A RS R + S SS A
Sbjct: 1056 RSMMSAYERSMM-SAYERSMMSPMADRSMMSMGADR----SMMSSYSAADRSMMSSYSAA 1110
Query: 328 TKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLS 387
+ S Y D+ S S + + T E PL E P + P
Sbjct: 1111 DRSMMSSYT---ADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEE----PPTMPPLPPE 1163
Query: 388 QEPVNPPSEASPTRDRSPPKSPEKLP------QSSSSESSPPSPQPTKVSRHASSSPESP 441
+ P+ PP PP+ P + P + ++E++ P+ P+ S + S PE P
Sbjct: 1164 EPPMTPPL---------PPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPP 1214
Query: 442 -------KPAPAPGSHREISSSPT 458
+P+ P + +S P+
Sbjct: 1215 VSQSEISEPSAVPTDYSVSASDPS 1238
Score = 37.7 bits (86), Expect = 0.16
Identities = 70/286 (24%), Positives = 104/286 (36%), Gaps = 35/286 (12%)
Query: 178 SSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSK 237
S PT + KK KK + +++ ++E++K K K+ ESESK + H +
Sbjct: 94 SVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEK--KYKRQPEESESKTKSHDDGNIDLE 151
Query: 238 RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS--------SSDTSRSR-SRSAAAKTHT 288
S K + +R S + +S + S + S + T T
Sbjct: 152 SDSFLKFDSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKT 211
Query: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTS-----TQRPSSPETATKQPSSPYEDKDKDKK 343
L+ S S S + + A EP T P T + S P + +
Sbjct: 212 AELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQ 271
Query: 344 EKSATR--PSPSPERSSTG-PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPT 400
KS + S SPE S EPP L +P T +S E P+E P
Sbjct: 272 MKSVLKSVESTSPEPSKIMLVEPPVAKVL---------EPSETLVVSSE---TPTEVYPE 319
Query: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKV-SRHASSSPESPKPAP 445
S + P+SS+ E+ QP V S A SS P+ P
Sbjct: 320 PSTS---TTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELP 362
Score = 37.4 bits (85), Expect = 0.21
Identities = 72/316 (22%), Positives = 113/316 (35%), Gaps = 51/316 (16%)
Query: 170 PYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRS-----ESES 224
P + S + K KKKKKKK++ E R+ + SK K H ES+S
Sbjct: 99 PTDEIPTKKSKKHKKHKNKKKKKKKEK----EKKYKRQPEESESKTKSHDDGNIDLESDS 154
Query: 225 KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAA 284
+ P+ + + +PA S +T + +++A
Sbjct: 155 FLKFDSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAEL 214
Query: 285 KTHTTALAGRS--------PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE 336
+T++ P P+ + + A P TT + S P S Y+
Sbjct: 215 SVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTM---SVEYQ 271
Query: 337 DKDKDKKEKSATRPSPSPERSSTGPE----PPAPTPLLAERHGGS--PQPLATTP----- 385
K K +S T P PS P P+ T +++ P+P +T
Sbjct: 272 MKSVLKSVES-TSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPE 330
Query: 386 --------LSQEPVNPPSE---ASPTRDRSPPKSPEKLP---QSSSSESSPPSPQPTKVS 431
L ++PV+ PSE +S TR + P+ P+ Q SS S+ P P
Sbjct: 331 SSAIEALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPP--- 387
Query: 432 RHASSSPESPKPAPAP 447
A+S PE P P
Sbjct: 388 --ATSMPELQGPPVTP 401
Score = 35.4 bits (80), Expect = 0.78
Identities = 59/257 (22%), Positives = 82/257 (31%), Gaps = 59/257 (22%)
Query: 204 SPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS 263
SP ER S + RS + +R SP S R S + A +S + S
Sbjct: 1051 SPMAERSMMSAYE--RSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYS 1108
Query: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGR------------------SPSPASGRRGE 305
+ S SS T+ S AA ++T + P P
Sbjct: 1109 AADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMT 1168
Query: 306 GDAPFSEP----------------GTTSTQRPSSP-ETATKQPSSPYEDKDKDK------ 342
P EP T T+ PSSP E + QP P + +
Sbjct: 1169 PPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPT 1228
Query: 343 -------------KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
E + T P P PE S+ P + ++AE H P+ T +S+
Sbjct: 1229 DYSVSASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSE- 1287
Query: 390 PVNPPSEASPTRDRSPP 406
P A PT S P
Sbjct: 1288 --TPAMSAEPTVLASEP 1302
Score = 33.1 bits (74), Expect = 3.9
Identities = 46/238 (19%), Positives = 82/238 (34%), Gaps = 6/238 (2%)
Query: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRN 1335
E VS ++ QS+ S+ + PSM +P E +E++
Sbjct: 213 ELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQM 272
Query: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQS-TRSSGHSSSELSPDAVEKA 1394
L + +T + P LE +L + ++ T S+ + D E +
Sbjct: 273 KSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESS 332
Query: 1395 GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
+ + + PV PS SS + P+ LP+T + + S + G P
Sbjct: 333 AIEALRLPEQPV-----DVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPP 387
Query: 1455 SRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTP 1512
+ P + + P + P P + P P + + PEL +TP
Sbjct: 388 ATSMPELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTP 445
Score = 32.3 bits (72), Expect = 6.6
Identities = 53/266 (19%), Positives = 95/266 (35%), Gaps = 18/266 (6%)
Query: 2411 PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAF-----SDQSRCLIAQ 2465
PS ++S P S + + L PA V S S+QS ++ +
Sbjct: 176 PSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVAVMPE 235
Query: 2466 TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQ 2525
+ S ++ V TTT ++++ S + +++ +PS + ++
Sbjct: 236 PSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTS--PEPSKIMLVE 293
Query: 2526 PAKERRSSSSSS---SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582
P + S + SS + + S+S++ SS E LP QP V P
Sbjct: 294 PPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQP------VDVP 347
Query: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
+ ++ RP E + SS +S+ ++S +
Sbjct: 348 SEIADSSMT--RPQELPELPKTTALELQESSVASAMELPGPPATSMPELQGPPVTPVLEL 405
Query: 2643 SSSSSSPSPAKPGPQALPKPASPKKP 2668
S++P P PGP + P P P P
Sbjct: 406 PGPSATPVPELPGPLSTPVPELPGPP 431
Score = 32.0 bits (71), Expect = 8.6
Identities = 78/383 (20%), Positives = 129/383 (33%), Gaps = 53/383 (13%)
Query: 2164 IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA-----AGLAARMSQVPAPVPLM 2218
+P+ T + ++ A + + T + L ++ P +MS + L + S P P +M
Sbjct: 233 MPEPSMTKILDSFAAAPVPT--TTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKIM 290
Query: 2219 SLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVA 2278
L P A + P+ + + P+ D +A A+ L V
Sbjct: 291 -LVEPPVAKVLE--PSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVP 347
Query: 2279 PSAVNLADPRT---PTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPAS 2335
+ + R P P + + +A+ L G P A + P P P
Sbjct: 348 SEIADSSMTRPQELPELPKTTALELQESSVASAMELPG----PPATSMPELQGPPVTPV- 402
Query: 2336 ANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSG 2395
L GP S T P L++ P L G P +A + G
Sbjct: 403 LELPGP-------------SATPVPELPGPLSTP--VPELPGP-------PATAVPELPG 440
Query: 2396 RTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP---VP 2452
+ P+ ++ APS + P P + P L+ A + P P V
Sbjct: 441 PSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVA 500
Query: 2453 SAFSDQSRCLIAQTTPVAGSQSLSSG--AVATTTSSAGDHNGMLSVPAPGVPHS----DV 2506
++Q PV + G V T T G + + PG P + ++
Sbjct: 501 MELTEQPVTTTELEQPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALEL 560
Query: 2507 GEPPASTGAQQ----PSALAALQ 2525
P+ TG + PSA AL+
Sbjct: 561 PGQPSVTGVPELPGLPSATRALE 583
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 150 bits (379), Expect = 2e-35
Identities = 134/360 (37%), Positives = 187/360 (51%), Gaps = 45/360 (12%)
Query: 489 TAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT 548
T GR K G R RS RS S RSRS R R +S R G S+S ++
Sbjct: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHS-----RSRSRSRHSR-KSRSRSGSSKSSHS 216
Query: 549 QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRT 608
+ R RSRS R RS SRS RS+SR+ +++ +SRS + + RSRS + + RS+S+
Sbjct: 217 KSRSRSRSGSRSRSKSRS-----RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271
Query: 609 PARR--------GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660
A G+ +SR+P+R +S++ +SRSRS RR R RGRS+
Sbjct: 272 QAEEKIQNNDNVGKPKSRSPSRHKSKS------KSRSRSQERRV-EEEKRGSVSRGRSQE 324
Query: 661 RTPARRGRSRSRTPARRSGRSRSRTPA---RRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
++ R+ RSRSR+ RSRSR+ + R+GR RSR R RSRSRS + RS R
Sbjct: 325 KS-LRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS--KSERSRKRG 381
Query: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNS-----SPEMKKSRISSRRSRSLSSPRSKAKSR 772
+R ++G SS++K K T + +SRS S E KS S R R S +
Sbjct: 382 SKRDSKAG-SSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET 440
Query: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
S RS S S P +S++ RS+S S K +SR+ RSRS+S P + +S++ SR
Sbjct: 441 RSRSRSNSKSKPNLPSESRS---RSKSAS---KTRSRS-KSRSRSASRSPSRSRSRSHSR 493
Score = 142 bits (359), Expect = 3e-33
Identities = 123/326 (37%), Positives = 176/326 (53%), Gaps = 42/326 (12%)
Query: 539 RPGWSRSRNTQRRGRSRSARRGRS-HSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSR 597
+PG SR R + R RS S R RS HSR + RSRS + ++ S+SR+ +R SRSR
Sbjct: 176 KPG-SRRRRSYSRSRSHSRSRSRSRHSR----KSRSRSGS-SKSSHSKSRSRSRSGSRSR 229
Query: 598 TPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS-------GRSRSR 650
+ +R RS+SR+ +++ +SRS + + RSR+ S + RS+S+ A G+ +SR
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 651 TPAR---RGRSRSRTPARR---------GRSRSRTPARRSGRSRSRTPARRGRSRSRTPR 698
+P+R + +SRSR+ RR R RS+ + R RSRSR+ +G SRSR+
Sbjct: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS---KGGSRSRSRS 346
Query: 699 RGRSRSRSLVRRGRSHSRTPQR-RGRSGSSSERKNKSRTSQRRSRSNSSPEMKK---SRI 754
R +S+ + R+GR SR R R RS S SER K R S+R S++ SS + KK R
Sbjct: 347 RSKSKDK---RKGRKRSREESRSRSRSRSKSERSRK-RGSKRDSKAGSSKKKKKEDTDRS 402
Query: 755 SSRR-SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813
SR SRS+S R AKS S R G S +T R + S+P S +
Sbjct: 403 QSRSPSRSVSKEREHAKSESSQREG-RGESENAGTNQETRSRSRSNSKSKPNLPSES--- 458
Query: 814 RSRSSSSPPPKQKSKTPSRQSHSSSS 839
RSRS S+ + +SK+ SR + S S
Sbjct: 459 RSRSKSASKTRSRSKSRSRSASRSPS 484
Score = 142 bits (357), Expect = 6e-33
Identities = 119/333 (35%), Positives = 171/333 (51%), Gaps = 38/333 (11%)
Query: 447 PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS 506
PGS R S S ++RSH R++ HS R G S+S + R RSRS + R S
Sbjct: 177 PGSRRRRSYS---RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGS---RSRS 230
Query: 507 RSRSPQWRRSRSAQRWGRSRSPQR-RGRSRSPQRPGWSRSRNTQRRGRS--RSARRGRSH 563
+SRS RSRS + +SRSP + + RSRS G SRS++ + + G+
Sbjct: 231 KSRSRSQSRSRSKKE--KSRSPSKEKSRSRS-HSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 564 SRSPA---TRGRSRSRTPARR---------GRSRSRTPARRRSRSRTPTRRRSRSRTPAR 611
SRSP+ ++ +SRSR+ RR R RS+ + R+SRSR+ ++ SRSR+
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS--- 344
Query: 612 RGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRS 671
R RS+S+ + R R+R R RSRSRS + RS + S+ ++ G S+ + RS+S
Sbjct: 345 RSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS 404
Query: 672 RTPARRSGRSR----SRTPARRGRSRSR---TPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
R+P+R + R S + R GR S T + RSRSRS +S P RS
Sbjct: 405 RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRS---NSKSKPNLPS-ESRS 460
Query: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSR 757
S S K +SR+ R ++ SP +SR SR
Sbjct: 461 RSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 137 bits (344), Expect = 2e-31
Identities = 126/361 (34%), Positives = 180/361 (49%), Gaps = 51/361 (14%)
Query: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRSRT-PARRGRSRSRTPARRRSRTRSPVRRRSRS 637
+RR RS SR+ + RSRSR+ R+SRSR+ ++ S+SR+ +R SR+RS R RS+S
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 638 RSPARRSGRSRSRTPAR-RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696
RS RS + +SR+P++ + RSRS + A + RS+S+ A ++ + RS SR
Sbjct: 239 RS---RSKKEKSRSPSKEKSRSRSHS-AGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 697 PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR---RSRSNSSPEMKKSR 753
+ +SRSRS RR R RGRS S R+++SR+ + RSRS S + K R
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
Query: 754 ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813
+RSR S RS+++S+ S R GS R S++GSS+ K K T
Sbjct: 355 KGRKRSREESRSRSRSRSK-SERSRKRGSK-----------RDSKAGSSKKKKKEDTDRS 402
Query: 814 RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCF 873
+SRS PSR S S H K +S +G + N+++ + RS
Sbjct: 403 QSRS------------PSR-SVSKEREHAKSESSQREGRGESENAGTNQET---RSRSRS 446
Query: 874 ESSPDPELKSRTPSRHSCSGSSPPRVKS-STPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932
S P L S + SR + + R KS S +SPSRS R RSHS
Sbjct: 447 NSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS-------------RSRSHSR 493
Query: 933 S 933
S
Sbjct: 494 S 494
Score = 136 bits (343), Expect = 2e-31
Identities = 113/348 (32%), Positives = 166/348 (47%), Gaps = 33/348 (9%)
Query: 1699 RKARL------SRRSRSASSS-PETRSRTPPRH-RRSPSVSSPEPAEKSRSSRRRRSASS 1750
RK RL SRR RS S S +RSR+ RH R+S S S + S+S R RS S
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 1751 PRTKTTSR---RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807
R+K+ SR R RS K R + +SRSR +R + + + + + +
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 1808 SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR 1867
SR R + S SRS R+ RGRS+ + RSRSR+ RSRSR
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 1868 ASPATHRRSRSRTPLISRRRSRSRT-SPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSR 1926
+ R+ R R+ SR RSRSR+ S SR+R R S + + R +SRS
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 1927 TPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRT 1986
+ V++ R +++ +++R R + + RSRSR++ S+S+
Sbjct: 408 SRSVSKEREHAKSESSQREGRGESENAGTNQET---------RSRSRSN------SKSKP 452
Query: 1987 SPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRT 2034
+ + RSRS+++ TR RS+SR+ RS SR+P R RS SR+
Sbjct: 453 NLPSESRSRSKSASKTRSRSKSRS------RSASRSPSRSRSRSHSRS 494
Score = 135 bits (339), Expect = 7e-31
Identities = 117/330 (35%), Positives = 168/330 (50%), Gaps = 36/330 (10%)
Query: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813
K SRR RS S + R RSRSRSR + + R RSGSS+S S + RSRSRS R
Sbjct: 176 KPGSRRRRSYS-RSRSHSRSRSRSRHSR----KSRSRSGSSKS-SHSKSRSRSRSGSRSR 229
Query: 1814 RRGGSGYHSRSPARQESSRTSSRRR-RGRSRTPPTSRKRSRSRTSPA---------PWKR 1863
+ S SRS +++E SR+ S+ + R RS + SR +S+ + P R
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 1864 SRSRASPATHRRSRS--------RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA 1915
S SR + RSRS + +SR RS+ ++ SR RSRS+ +R RSRSR+
Sbjct: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG-SRSRSRSRS 348
Query: 1916 SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR-SRTPPVTRRRSRSRTPPVTRRRSRSRT 1974
+R+ R R+ +R RSRSR+ + R R R S+ + + R +SRS +
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408
Query: 1975 SPITRRRSRSRTSPVTRR----RSRSRTSPVTRRRSR--SRTSPVTRRRSRSRTPPAIRR 2028
+++ R +++ R + T+ TR RSR S++ P SRSR+ A +
Sbjct: 409 RSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
Query: 2029 RSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
RSRS++ R RS SRSP R RS SR+
Sbjct: 469 RSRSKS----RSRSASRSPSRSRSRSHSRS 494
Score = 129 bits (325), Expect = 3e-29
Identities = 115/368 (31%), Positives = 172/368 (46%), Gaps = 54/368 (14%)
Query: 1660 EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
E P SR R SRS R+ R RS ++R SR+SRS S S ++
Sbjct: 174 EDKPGSRRRRSYSRS--------RSHSRSRS---------RSRHSRKSRSRSGSSKS--- 213
Query: 1720 TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPS-----PKPRGLQRSR 1774
S S S SRS + RS S R+++ + RSPS + +SR
Sbjct: 214 -------SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSR 266
Query: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834
S+S+ + + D G +S S R +S+S+SR SRS R+
Sbjct: 267 SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR------------SRSQERRVEEEKR 314
Query: 1835 SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRT-S 1893
RGRS+ + RSRSR+ RSRSR+ R+ R R+ SR RSRSR+ S
Sbjct: 315 GSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS 374
Query: 1894 PVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPV 1953
SR+R R S + + R +SRS + V++ R +++ +++R R +
Sbjct: 375 ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
Query: 1954 -TRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSP 2012
T + +RSR +R S+S+ + + RSRS+++ TR RS+SR+ +R SRSR
Sbjct: 435 GTNQETRSR----SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSR--- 487
Query: 2013 VTRRRSRS 2020
+R SRS
Sbjct: 488 -SRSHSRS 494
Score = 127 bits (320), Expect = 1e-28
Identities = 118/332 (35%), Positives = 167/332 (50%), Gaps = 42/332 (12%)
Query: 416 SSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT-----SKNRSHGRAKRD 470
S S S S ++ SR + S S K + + R S S + S+++S R+K++
Sbjct: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 471 KSHSHTPSRRMGRSRSPATAK-RGRSRSRTPTK------RGHSRSRSPQWRRSRSAQRWG 523
KS S PS+ RSRS + K R +S+ + K G +SRSP +S+S
Sbjct: 246 KSRS--PSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS----- 298
Query: 524 RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRS--RSARRGRSHSRSP-ATRGRSRSRTPA- 579
+ RSRS +R R + RGRS +S R+ RS SRS +R RSRSR+ +
Sbjct: 299 -------KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
Query: 580 --RRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS 637
R+GR RSR +R RSRSR+ + RSR R R ++ S ++ RS R SRS
Sbjct: 352 DKRKGRKRSREESRSRSRSRSKS-ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
Query: 638 RSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTP 697
S R +S S RG S + + RSRSR+ + +S+ P+ RSRS++
Sbjct: 411 VSKEREHAKSESSQREGRGESENAGTNQETRSRSRS----NSKSKPNLPS-ESRSRSKSA 465
Query: 698 RRGRSRSRSLVRRGRSHSRTPQR-RGRSGSSS 728
+ RSRS+S R RS SR+P R R RS S S
Sbjct: 466 SKTRSRSKS---RSRSASRSPSRSRSRSHSRS 494
Score = 126 bits (316), Expect = 3e-28
Identities = 104/332 (31%), Positives = 163/332 (49%), Gaps = 19/332 (5%)
Query: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
+K + RRR S S SR RSRSRSR +R+ R SG S ++ S S R R
Sbjct: 175 DKPGSRRRR-----SYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229
Query: 1840 GRSRTPPTSRKRSRSRTSPAPWK-RSRSRASPATHRRSRSRTPLISRRRSRSRTS-PVSR 1897
+SR+ SR RS+ S +P K +SRSR+ A RS+S+ + ++ P SR
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 1898 RRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR 1957
SR ++ +S+SR+ RR + V+R RS+ ++ + RSRSR+ +R R
Sbjct: 290 SPSRHKS-----KSKSRSRSQERRVEEEKRGSVSRGRSQEKS-LRQSRSRSRSKGGSRSR 343
Query: 1958 SRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRR 2017
SRSR+ +R+ R R+ +R RSRSR+ R+ S+ + + R +
Sbjct: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
Query: 2018 SRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSL-----TRSP 2072
SRS + + R +++ R+ + +RSR+ ++ K +L +RS
Sbjct: 404 SRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSK 463
Query: 2073 PAIRRRSASGSSSDRSRSATPPATRNHSGSRT 2104
A + RS S S S RS S +P +R+ S SR+
Sbjct: 464 SASKTRSRSKSRS-RSASRSPSRSRSRSHSRS 494
Score = 125 bits (315), Expect = 4e-28
Identities = 118/369 (31%), Positives = 175/369 (47%), Gaps = 47/369 (12%)
Query: 1739 SRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTS 1798
S S +R T+ R+ R KP G +R RS SR +R R R
Sbjct: 149 SYSDMKRALEKLDGTEVNGRKIRLVEDKP-GSRRRRSYSRSRSHSRSRSRSRHS------ 201
Query: 1799 RRRQRSRS----RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRS 1854
R+ RSRS S R R SG SRS +R S++ SR ++ +SR+P S+++SRS
Sbjct: 202 -RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR-SQSRSRSKKEKSRSP--SKEKSRS 257
Query: 1855 RTSPAPWKRSRSR------------------ASPATHR-RSRSRTPLISRRRSRSRTSPV 1895
R+ A RS+S+ SP+ H+ +S+SR+ RR + V
Sbjct: 258 RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV 317
Query: 1896 SRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRT-PTTRRRSRSRTPPVT 1954
SR RS+ + S+ + RSRSR+ SR RSRSR+ +R+ R R+ +R RSRSR+
Sbjct: 318 SRGRSQEK-SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
Query: 1955 RRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT 2014
R+ S+ + + R +SRS + V++ R +++ R + T
Sbjct: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
Query: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPA 2074
+ +RSR+ R S+S+ L RSRS+S R RS+SR+ RS +RSP
Sbjct: 437 NQETRSRS----RSNSKSKPNLPSESRSRSKSASKTRSRSKSRS-------RSASRSPSR 485
Query: 2075 IRRRSASGS 2083
R RS S S
Sbjct: 486 SRSRSHSRS 494
Score = 124 bits (311), Expect = 1e-27
Identities = 106/317 (33%), Positives = 156/317 (49%), Gaps = 32/317 (10%)
Query: 1827 RQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR 1886
R + SRRRR SR+ SR RSRSR S RSRS +S ++H +SRSR+ SR
Sbjct: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRK--SRSRSGSSKSSHSKSRSRSRSGSRS 228
Query: 1887 RSRSRTSPVSRRRSRSRTSVT----RRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTT 1942
RS+SR+ SR RS+ S + + RSRS ++ SR +S+ + + P +
Sbjct: 229 RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
Query: 1943 RRRSRSRTPPVTRRRSRSRTPPVTRR----RSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
R SR ++ +R RS+ R +R R RS+ + + RSRSR+ +R RSRSR+
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
Query: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPP------AIRRRSRSRTPLLPRK----RSRSRSPL 2048
+R+ R R+ +R RSRSR+ +R S++ + +K RS+SRSP
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408
Query: 2049 AIRRRSRSR-----TPRTARGKRSLTRSPPAIRRRSASGS-------SSDRSRSATPPAT 2096
+ R + R RG+ + R RS S S S RSRS + T
Sbjct: 409 RSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
Query: 2097 RNHSGSRTPPVALNSSR 2113
R+ S SR+ + + SR
Sbjct: 469 RSRSKSRSRSASRSPSR 485
Score = 120 bits (302), Expect = 1e-26
Identities = 115/350 (32%), Positives = 158/350 (45%), Gaps = 55/350 (15%)
Query: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
S S S S++++R + RSRSGSS SKSR RSRSGS K + R+ R++S
Sbjct: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSR---SRSRSGSRSRSKSRSRSQSRSRS 242
Query: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSP 1676
+ S P R SRS S+ K R S K + + +
Sbjct: 243 KKEKSRSPSKEKSR-----SRSHSAGKSRSKS---------------KDQAEEKIQNNDN 282
Query: 1677 EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPA 1736
K KSR+P R +S S RSRS E R RS S +
Sbjct: 283 VGKPKSRSPSRHKSKSKS-----------RSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
Query: 1737 EKSRSSRRRRSASSPRTKTTSRR-GRSPS-PKPRGLQRSRSRSRREKTRTTRRRDRSGSS 1794
+SRS RS S R+K+ +R GR S + R RSRS+S R + R ++R ++GSS
Sbjct: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
Query: 1795 -----QSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR-----RRRGRSRT 1844
+ T R + RS SRS V++ R S+ R ES + R R S++
Sbjct: 392 KKKKKEDTDRSQSRSPSRS-VSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKS 450
Query: 1845 PPT--SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRT 1892
P S RSRS+++ RS+SR+ RS SR+P SR RS SR+
Sbjct: 451 KPNLPSESRSRSKSASKTRSRSKSRS------RSASRSPSRSRSRSHSRS 494
Score = 119 bits (297), Expect = 5e-26
Identities = 112/351 (31%), Positives = 155/351 (44%), Gaps = 45/351 (12%)
Query: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615
RS S S S+++ R RS S S S+S RSRSGS K + R+ R++
Sbjct: 187 RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRS-----RSRSGSRSRSKSRSRSQSRSR 241
Query: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675
S + K+ +P RSRS S+ K R S K + + +
Sbjct: 242 SKKE-----KSRSPSKEKSRSRSHSAGKSRSKS---------------KDQAEEKIQNND 281
Query: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735
K KSR+P R +S S RSRS E R RS S +
Sbjct: 282 NVGKPKSRSPSRHKSKSKS-----------RSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
Query: 1736 AEKSRSSRRRRSASSPRTKT-TSRRGRSPS-PKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793
+SRS RS S R+K+ R+GR S + R RSRS+S R + R ++R ++GS
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS 390
Query: 1794 SQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSR 1853
S+ ++ RS+SR R H++S + Q R S T SR RS
Sbjct: 391 SKK-KKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET--RSRSRSN 447
Query: 1854 SRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT 1904
S++ P SRSR+ A+ RSRS+ SR RS SR+ SR RS SR+
Sbjct: 448 SKSKPNLPSESRSRSKSASKTRSRSK----SRSRSASRSPSRSRSRSHSRS 494
Score = 117 bits (292), Expect = 2e-25
Identities = 109/361 (30%), Positives = 177/361 (49%), Gaps = 53/361 (14%)
Query: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
S+ R S RSRS S + + R++SGS S K+ RSRS S S+ R
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS--------RSRSRSGSRSRS 230
Query: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRR 1706
S S S +SR+ + SRS + K++SR+ +S S K + +
Sbjct: 231 KSRSRSQS---------RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKS-----KDQAEEK 276
Query: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
++ + + +SR+P RH+ KSRS + R + + SR GRS +
Sbjct: 277 IQNNDNVGKPKSRSPSRHKSK---------SKSRSRSQERRVEEEKRGSVSR-GRS---Q 323
Query: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS--------RSRSRVTRRRRGGS 1818
+ L++SRSRSR + +R R RS S+ + R+RS RSRS+ R R+ GS
Sbjct: 324 EKSLRQSRSRSRSKGGSRSRSRSRS-KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGS 382
Query: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878
S++ + ++ + + R + RS + S++R +++ + + + T++ +RS
Sbjct: 383 KRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRS 442
Query: 1879 RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
R SR S+S+ + S RSRS+ S ++ RSRS+ SR RS SR+P +R RS SR
Sbjct: 443 R----SRSNSKSKPNLPSESRSRSK-SASKTRSRSK----SRSRSASRSPSRSRSRSHSR 493
Query: 1939 T 1939
+
Sbjct: 494 S 494
Score = 113 bits (282), Expect = 3e-24
Identities = 104/333 (31%), Positives = 151/333 (45%), Gaps = 32/333 (9%)
Query: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694
RS S S S+ R S S S H +R GSRS K++SR+ R RS +
Sbjct: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS--RSKSRSRSQSRSRSKKEK 246
Query: 1695 PELTRKARLSRRSRSASSS-PETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753
K + RS SA S +++ + + + + +V P KSRS R +S S R+
Sbjct: 247 SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP----KSRSPSRHKSKSKSRS 302
Query: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRV--- 1810
++ RR + RG SR RS+ + R +R R RS RSRSRSR
Sbjct: 303 RSQERRVEE---EKRG-SVSRGRSQEKSLRQSRSRSRSKGGS-------RSRSRSRSKSK 351
Query: 1811 -TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS 1869
R+ R S SRS +R S SR+R + + S K+ + + RS SR+
Sbjct: 352 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411
Query: 1870 PATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPP 1929
++S + R RSRSR++ S+S+ + S RSRS++
Sbjct: 412 SKEREHAKSESSQREGRGESENAGTNQETRSRSRSN-----SKSKPNLPSESRSRSKSAS 466
Query: 1930 VTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
TR RS+SR+ RS SR+P +R RS SR+
Sbjct: 467 KTRSRSKSRS-----RSASRSPSRSRSRSHSRS 494
Score = 112 bits (279), Expect = 7e-24
Identities = 139/497 (27%), Positives = 208/497 (41%), Gaps = 93/497 (18%)
Query: 144 SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESS 203
SY G S RR+ K P + Y L+ E+ SSR K ++ +++
Sbjct: 78 SYGSGRSGYGYRRSGRDKYGPPTRTE-YRLIVENLSSRCSWQDLKDYMRQAGEVTYADAH 136
Query: 204 SPRRER----------KKSSKKKKHRSESESKKRKHRSPTPKSKRK-SKDKKRKRSRSTT 252
R+ K + +K +E +K + P S+R+ S + R SRS +
Sbjct: 137 KGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRS 196
Query: 253 PAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE 312
+ SR++ RS S S SS SRSRSRS + RS S + R
Sbjct: 197 RSRHSRKS-RSRSGSSKSSHSKSRSRSRSGS----------RSRSKSRSR---------- 235
Query: 313 PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE 372
S R S + ++ PS KEKS +R S S +S + + A +
Sbjct: 236 ----SQSRSRSKKEKSRSPS----------KEKSRSR-SHSAGKSRSKSKDQAEEKIQ-- 278
Query: 373 RHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR 432
+ + V P SP+R +S KS +S S E + VSR
Sbjct: 279 --------------NNDNVGKPKSRSPSRHKSKSKS-----RSRSQERRVEEEKRGSVSR 319
Query: 433 HASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKR 492
S S R+ S SK G R +S S + +R GR RS +
Sbjct: 320 GRSQEK----------SLRQSRSRSRSKG---GSRSRSRSRSKSKDKRKGRKRS---REE 363
Query: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG 552
RSRSR+ +K SR R + R S++ + + R +SRSP R S S+ +
Sbjct: 364 SRSRSRSRSKSERSRKRGSK-RDSKAGSSKKKKKEDTDRSQSRSPSR---SVSKEREHAK 419
Query: 553 RSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARR 612
S R GR S + T +RSR+ + +S+ P+ RSRS++ ++ RSRS++ R
Sbjct: 420 SESSQREGRGESENAGTNQETRSRSRS-NSKSKPNLPSESRSRSKSASKTRSRSKS---R 475
Query: 613 GRSRSRTPARRRSRTRS 629
RS SR+P+R RSR+ S
Sbjct: 476 SRSASRSPSRSRSRSHS 492
Score = 109 bits (272), Expect = 4e-23
Identities = 122/406 (30%), Positives = 171/406 (42%), Gaps = 39/406 (9%)
Query: 1419 SSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRS 1478
SS S ++KD + R + + + G R G S S ++ + T GR
Sbjct: 112 SSRCSWQDLKDYM-RQAGEVTYADAHKG-RKNEGVIEFVSYSDMKRALEKLDGTEVNGRK 169
Query: 1479 ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR 1538
+P + + RSRS S ++ R RSGS S K+ +R+ G RSR
Sbjct: 170 IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229
Query: 1539 SGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPE--------VDSKSR 1590
S S + S S +E+S S S S++++ + + RS+S E V
Sbjct: 230 SKSRSRSQSR-SRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
Query: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
SP R +S S + + R + GS S + + R RSRS S+ R S
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
Query: 1651 GSSSTESSPEHPPKSRTARRG-SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
KS+ R+G RS E +++SR SRS E +RK R S++
Sbjct: 349 -------------KSKDKRKGRKRSREESRSRSR-------SRSKSERSRKRGSKRDSKA 388
Query: 1710 ASSSPETRSRTPPRHRRSP--SVSSPEPAEKSRSSRRRRSASSPRTKT---TSRRGRSPS 1764
SS + + T RSP SVS KS SS+R S T T R RS S
Sbjct: 389 GSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS 448
Query: 1765 -PKPRGLQRSRSRSRREKTRTTRRRDRSGS-SQSTSRRRQRSRSRS 1808
KP SRSRS+ +R + RS S S+S SR R RS SRS
Sbjct: 449 KSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 109 bits (272), Expect = 4e-23
Identities = 104/326 (31%), Positives = 151/326 (46%), Gaps = 48/326 (14%)
Query: 402 DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKN 461
D+ + +S S S + ++ SR S S +S S S S++
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 462 RSHGRAKRDKSHSHTPSRRMGRSRSPATAKR------------------GRSRSRTPTK- 502
RS R++ K S +PS+ RSRS + K G+ +SR+P++
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 503 --RGHSRSRSPQWR---RSRSAQRWGRSRSPQ-RRGRSRSPQRPGWSRSRNT-------Q 549
+ SRSRS + R R + GRS+ R+ RSRS + G SRSR+ +
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG-SRSRSRSRSKSKDK 353
Query: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARR----RSRSRTPTRRRSR 605
R+GR RS RS SRS + RSR R R ++ S ++ RS+SR+P+R S+
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 606 SRTPA------RRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSR 659
R A R GR S A TRS R S+S+ RSRS++ A + RSR
Sbjct: 414 EREHAKSESSQREGRGESEN-AGTNQETRSRSRSNSKSKPNLPSESRSRSKS-ASKTRSR 471
Query: 660 SRTPARRGRSRSRTPARRSGRSRSRT 685
S++ R RS SR+P+R RS SR+
Sbjct: 472 SKS---RSRSASRSPSRSRSRSHSRS 494
Score = 100 bits (250), Expect = 2e-20
Identities = 103/324 (31%), Positives = 143/324 (44%), Gaps = 17/324 (5%)
Query: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
RR SRSR+ +R RSRSR R+ RSRS S SHS++ + R RSGS S K++SR
Sbjct: 181 RRRSYSRSRSHSR-SRSRSRHSRKSRSRSGS---SKSSHSKS-RSRSRSGSRSRSKSRSR 235
Query: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795
SQ RSRS S+ S RSRS S+ +S++KS+ + + K KS++P R
Sbjct: 236 -SQSRSRSKKEKSRSPSKEKS-RSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 796 RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSI 855
S+ +++ R R S S Q+ RQS S S +S + R S
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSL--RQSRSRSRSKGGSRSRSRSRSKSK 351
Query: 856 TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ--SPSRSS 913
+ ++S R S + R R S +GSS + K T Q SPSRS
Sbjct: 352 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411
Query: 914 SPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPR-----YS 968
S + + A QR G S + + +R+ R + P ESR + S
Sbjct: 412 SKE-REHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRS 470
Query: 969 HSGSSSPDTKVKPETPPRQSHSGS 992
S S S P +SHS S
Sbjct: 471 RSKSRSRSASRSPSRSRSRSHSRS 494
Score = 86.3 bits (212), Expect = 4e-16
Identities = 109/377 (28%), Positives = 149/377 (39%), Gaps = 54/377 (14%)
Query: 1354 DLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRT 1413
++NG + +E P + +RS HS S K+ S S SS +
Sbjct: 164 EVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSS-------HS 216
Query: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGS-SPGLRDGSGTPSRHSLSGSSPGMKDIPRT 1472
SR RS S S K RSRS S S ++ S +PS+ K R+
Sbjct: 217 KSRSRSRSGSRSRSKS--------RSRSQSRSRSKKEKSRSPSKE---------KSRSRS 259
Query: 1473 PSRGRSECDSSPEPKALPQTP----RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528
S G+S S + + Q +P+SRSPS + +S S S ++ V
Sbjct: 260 HSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR----------HKSKSKSRSRSQERRV 309
Query: 1529 ARTPLGQRSRSGSSQELDVKPSAS-PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
G SR G SQE ++ S S + + S S S++K++ + R RS S
Sbjct: 310 EEEKRGSVSR-GRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRS 368
Query: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGP 1647
+SR RSR R + R S + K R+ RS S S SK R
Sbjct: 369 RSRSKSERSRK----------RGSKRDSKAGSSKKKKKEDTDRS-QSRSPSRSVSKEREH 417
Query: 1648 SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
+ SS E E SRS K+K P RS S TR +R RS
Sbjct: 418 AKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTR-SRSKSRS 476
Query: 1708 RSASSSP-ETRSRTPPR 1723
RSAS SP +RSR+ R
Sbjct: 477 RSASRSPSRSRSRSHSR 493
Score = 82.8 bits (203), Expect = 4e-15
Identities = 108/419 (25%), Positives = 169/419 (40%), Gaps = 73/419 (17%)
Query: 130 KKNERLRAAFGISD-----SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPT 184
+KNE + SD +DG+ + ++ +P + YS R S SRS +
Sbjct: 139 RKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRS 198
Query: 185 PKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKK 244
+K + + + S S S R R S + K RS S+S+ R K
Sbjct: 199 RHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRS---------------K 243
Query: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
+++SRS S + SRSRS S AG+S S + +
Sbjct: 244 KEKSRS-------------------PSKEKSRSRSHS----------AGKSRSKSKDQAE 274
Query: 305 EGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPP 364
E G ++ PS ++ +K S E + +++K S +R S E+S
Sbjct: 275 EKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSR-GRSQEKSL------ 327
Query: 365 APTPLLAERHGGSPQPLATTPLSQEP---VNPPSEASPTRDRSPPKSPEKLPQSSSSESS 421
+ + GGS + S++ E S +R RS KS + S +S
Sbjct: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSK 387
Query: 422 PPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRM 481
S + K + + +S P+ + RE + S +S+ G ++ ++ T SR
Sbjct: 388 AGSSK--KKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSR 445
Query: 482 GRSRS-PATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQR 539
S+S P RSRS++ +K SRS+S RSRSA SRSP R RSRS R
Sbjct: 446 SNSKSKPNLPSESRSRSKSASKT-RSRSKS----RSRSA-----SRSPS-RSRSRSHSR 493
Score = 81.3 bits (199), Expect = 1e-14
Identities = 129/493 (26%), Positives = 185/493 (37%), Gaps = 93/493 (18%)
Query: 667 GRSRSRTPARRSGRSRSRTPAR---RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGR 723
G RS RRSGR + P R R + + R + +R+ + +GR
Sbjct: 80 GSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGR 139
Query: 724 SG-------SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR 776
S S+ K + + + + SRR RS S RS ++SR R
Sbjct: 140 KNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSR 199
Query: 777 -----RSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS 831
RS SGSS KS++ RSRSGS +SR+ R S S K+KS++PS
Sbjct: 200 HSRKSRSRSGSSKSSHSKSRS---RSRSGS-----RSRSKSRSRSQSRSRSKKEKSRSPS 251
Query: 832 RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSC 891
++ S S H KS + + + Q N+ P KSR+PSRH
Sbjct: 252 KEKSRSRS-HSAGKSRSKSKDQAEEKIQNNDNVGKP--------------KSRSPSRHKS 296
Query: 892 SGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSR 951
S R + + S + + K++ R RS S S S SR SR+ + R
Sbjct: 297 KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR--SRSKSKDKR 354
Query: 952 SVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSG 1011
S ESR S S S S + + R S +GS K K T S S
Sbjct: 355 KGRKRSREESR-----SRSRSRSKSERSRKRGSKRDSKAGSSKK--KKKEDTDRSQSRSP 407
Query: 1012 SKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDT 1071
S+S + + S S Q +G+ ++ +
Sbjct: 408 SRSVSKEREHAKS----------------------------ESSQREGRGESENAGTNQE 439
Query: 1072 SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGM 1131
+ R + P+L S+S RSRS S AS++ R SAS
Sbjct: 440 TRSRSRSNSKSKPNLPSES-------RSRSKS-----ASKTRSRSKSRSRSAS------R 481
Query: 1132 SPEQSRFQSDSSS 1144
SP +SR +S S S
Sbjct: 482 SPSRSRSRSHSRS 494
Score = 71.2 bits (173), Expect = 1e-11
Identities = 67/234 (28%), Positives = 100/234 (42%), Gaps = 11/234 (4%)
Query: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586
++ RRS S S S S S S S S S S SGSS S S S + R S + +
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS-SHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
+ R + +P+K K RS S S+ S S S + ++ + S S S S
Sbjct: 238 SRS-RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
Query: 2647 SSPSPAKPGPQAL--PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE------- 2697
S S ++ + + K S + E+ R R S SRS S S +
Sbjct: 297 KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356
Query: 2698 RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
R+R + R + S SER +RG + DS++ S K++++ + R SRS
Sbjct: 357 RKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
Score = 70.5 bits (171), Expect = 2e-11
Identities = 77/287 (26%), Positives = 117/287 (40%), Gaps = 33/287 (11%)
Query: 154 QRRAREAKQPAPEPPKPYSLVRESSS--SRSPTPKQKKKK-KKKDRGRRSESSSPRRERK 210
Q R+R K+ + P K S R S+ SRS + Q ++K + D + +S SP R +
Sbjct: 237 QSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
Query: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA-PKSRRAHRSTSADSA 269
KS K + RS+ + + R + + + K ++ RSRS + +SR RS S D
Sbjct: 297 KS--KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
Query: 270 SSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATK 329
SR SRS + RS S + R G S+ G S+++ +T
Sbjct: 355 KGRKRSREESRSRS----------RSRSKSERSRKRGSKRDSKAG--SSKKKKKEDTDRS 402
Query: 330 QPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
Q SP K+++ S S +R G A T S S+
Sbjct: 403 QSRSPSRSVSKEREHAK----SESSQREGRGESENAGTNQETRSRSRSN--------SKS 450
Query: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASS 436
N PSE +R RS S + S S S+ SP ++ H+ S
Sbjct: 451 KPNLPSE---SRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 68.6 bits (166), Expect = 8e-11
Identities = 84/334 (25%), Positives = 127/334 (38%), Gaps = 28/334 (8%)
Query: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ 2465
R R+ + S SR S S SR S+S ++ + RS S +SR
Sbjct: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 240
Query: 2466 TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG-VPHSD-VGEPPASTGAQQPSALAA 2523
+ S+S S + + SAG A + ++D VG+P + + ++ S +
Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 300
Query: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
++ERR S S S S S S S S R S +
Sbjct: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS--------------RSRSRS 346
Query: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
+ + R+GR KR R S S S S S S S S S + SS +
Sbjct: 347 RSKSKDKRKGR-------KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT 399
Query: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
S S SP++ ++ K K +R R + + +++RS S S + + P
Sbjct: 400 DRSQSRSPSR----SVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
Query: 2704 QPSPRDQQSSSSERG-SRRGQRGDSRSPSHKRRR 2736
S +S+S R S+ R SRSPS R R
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
Score = 59.3 bits (142), Expect = 5e-08
Identities = 71/248 (28%), Positives = 91/248 (36%), Gaps = 30/248 (12%)
Query: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
RS S S S S S S S S S S S S S S+ S R S A ++
Sbjct: 219 RSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
Query: 2591 RE---GRPPEPTPAKRKRRSSSSSSS-----------SSSSSSSSSSSSSSSSSSSSSSS 2636
G+P +P++ K +S S S S S S S S S S S S
Sbjct: 279 NNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKG 338
Query: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS-------- 2688
S S S S S S K ++ + S + RSR DS S
Sbjct: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398
Query: 2689 --RSLSYSP-----VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741
RS S SP ER + S R+ + S G+ + R SRS S K + PS
Sbjct: 399 TDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS-KSKPNLPSE 457
Query: 2742 RPMRHRSS 2749
R +S+
Sbjct: 458 SRSRSKSA 465
Score = 35.4 bits (80), Expect = 0.78
Identities = 52/227 (22%), Positives = 81/227 (35%), Gaps = 24/227 (10%)
Query: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
SR+P S + RS GS + SL +R G + + R
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD- 2445
+ ++ GR RSR + S+SR SER+ S+ S +D
Sbjct: 348 SKSKDKRKGRK--------RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT 399
Query: 2446 ---QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Q RSP S ++ + +S ++G T S + + S P +
Sbjct: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSN----SKSKPNL- 454
Query: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549
P+ + ++ SA +K R S+S S S S S S S S
Sbjct: 455 -------PSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 148 bits (373), Expect = 8e-35
Identities = 243/1169 (20%), Positives = 415/1169 (35%), Gaps = 120/1169 (10%)
Query: 27 RGRRGERPDYK--------GEEELRRLEAALVKRPNPDI-LDHERKRRVELRCLELEEMM 77
RGR E+ D K EEE E N DI D+ + +E++ +++ +
Sbjct: 118 RGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQREL 177
Query: 78 EEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRA 137
+ E + +E++ +++K+V+P P++ ++ + + +
Sbjct: 178 MKLEQENMEKREEI------IIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSAS 231
Query: 138 AFGISDSYVDGSSFDPQRRAR--EAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKD 195
S V D QR ++ ++K+ P P P + E + K K+K K KD
Sbjct: 232 KKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGK---KYKEKYKVKD 288
Query: 196 RGRRSESSSPRRERK-KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA 254
R R R + ++K+ + S S +H SP S + + +P+
Sbjct: 289 RIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPS 348
Query: 255 PKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPG 314
P+ +R T + S + T R ++ +H+ + R SP R +P E G
Sbjct: 349 PRRKR----TPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR-----SPMREKG 399
Query: 315 TTSTQRPSSPETAT---KQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLA 371
+R S ++ + D++KD +E+ S R P
Sbjct: 400 RHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREP------- 452
Query: 372 ERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVS 431
R G + +A TRDR + + S + ++
Sbjct: 453 -RDGRDRR----------------DARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDP 495
Query: 432 RHASSSPESPKPAPAPG--SHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489
R + S+ ++ G +HR+ + P ++RS+GR + S T R R+ S +
Sbjct: 496 RDSRSTRDAHDYRDREGRDTHRKEDTYP-EESRSYGRNHLREESSRTEIRNESRNESRSE 554
Query: 490 AKR---GRSRSRTPT--KRGHSRSRSPQWRRSRSAQRWG-----RSRSPQRRGRSRSPQR 539
+ GRSR R P ++G SR Q S + RS P+R R P+R
Sbjct: 555 IRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPER---DRYPER 611
Query: 540 PGWSRSRNT--QRRGRSRSARRGRSHSRSPAT------RGRSRSRTPARRGRSRSRTPAR 591
++R++ +RR R R R + P++ R R R R R R
Sbjct: 612 DNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDR 671
Query: 592 RRSRSRTPTRRRSRSRTPAR-RGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSR 650
R R+R R R R R R R R R R + R R R R R R R R R R
Sbjct: 672 RDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDR 731
Query: 651 TPAR-------RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSR 703
R R R + R R R R R R R R R R R+R R R R R
Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERER---ERERARERDKERERQR 788
Query: 704 SRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLS 763
+GR R + R + + R S++R R+ SP ++S R S
Sbjct: 789 DWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDS 848
Query: 764 SPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPP 823
+ + R LS + +S +P + + K + R P R+ S
Sbjct: 849 DAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQ 908
Query: 824 KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS 883
+ K K S + ++ + R I +E T R+ E+ +++
Sbjct: 909 ELKEKVSSVDKQREQT---EILESSRMRAQDIIGHHQSEDRETSD-RAHDENKKKAKIQK 964
Query: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTS 943
+ + R T S K K+I R++S G S S
Sbjct: 965 KPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKS-KGDSDISDEEAAQ 1023
Query: 944 RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPET----------PPR-----QS 988
++ +R P + E L+ + D++ K +T P R
Sbjct: 1024 QSKKKRGPRTPPITTKE-ELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAE 1082
Query: 989 HSGSI-----SPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSST 1043
H+ + +P P PP P + + + P + + + S S S+T
Sbjct: 1083 HTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSAT 1142
Query: 1044 PPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQT--SPKGGRSRS 1101
P + ++ + + + +T + + P Q +S + S + RS +
Sbjct: 1143 PTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHT 1202
Query: 1102 SSPVTELASRSPIRQDRGEFSASPMLKSG 1130
S + ++ S R + +L SG
Sbjct: 1203 SGRLRSPSNDSAHRSGDDQSGRKRVLHSG 1231
Score = 125 bits (314), Expect = 6e-28
Identities = 177/661 (26%), Positives = 234/661 (35%), Gaps = 59/661 (8%)
Query: 1496 RSRSPSSPELNNKCLTPQRE---RSGSESSVDQKTVA-RTPLGQRSRSGSSQELDVKP-- 1549
RS+ SP L +P+R+ +S S S D+KT A +PL + R+ + + K
Sbjct: 203 RSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPR 262
Query: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP-EVKDKP 1608
+ SP D + K K + ++ R ++ K+R R R E +DKP
Sbjct: 263 TPSPPPPIPEDIALGKKYKEKYKVKDR--------IEEKTRDGKDRGRDFERQREKRDKP 314
Query: 1609 RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH---PPKS 1665
R+ A G SP + R S+SGSS + PSP + S + PP
Sbjct: 315 RSTSPA--GQHHSPI----SSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLR 368
Query: 1666 RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR 1725
R+A S + ++PPR RS + K R S S R R +
Sbjct: 369 RSASPYPSHSLSSPQRKQSPPRHRSP-----MREKGRHDHERTSQSHDRRHERREDTRGK 423
Query: 1726 RSPSVSSPEPAEKSR---SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR----SRSR 1778
R S E E + SSR R PR R R + R L+ SR SR
Sbjct: 424 RDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR-RELRDSRDMRDSREM 482
Query: 1779 REKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGG----SGYHSRSPARQESSRTS 1834
R+ +R T+ S+ST R T R+ S + R+ R+ESSRT
Sbjct: 483 RDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTE 542
Query: 1835 SR---RRRGRSRTPPTSRKRSRSRTSPAPWKRSR-SRASPATHRRSRSRTPLISRRRS-- 1888
R R RS RSR R P K SR SR S S S RS
Sbjct: 543 IRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSY 602
Query: 1889 --RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946
R R P R ++R S RR R +R R + + P+ + RR
Sbjct: 603 PERDRY-PERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERRE 661
Query: 1947 RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2006
R V RR R R R R R R R R R + R R R
Sbjct: 662 ERRVDRVDDRRDER-----ARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 2007 RSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSR-TPRTARGK 2065
R R R R R R R R R R R+R R R R R R R +
Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKEREREREERE---RERERERERERERERE 773
Query: 2066 RSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPT 2125
R R R R D+ R R P + + R SP+
Sbjct: 774 RERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPS 833
Query: 2126 P 2126
P
Sbjct: 834 P 834
Score = 117 bits (293), Expect = 2e-25
Identities = 184/729 (25%), Positives = 257/729 (35%), Gaps = 98/729 (13%)
Query: 1435 PSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR 1494
PS R + G S R P+ +D+ P + +E SSP K +
Sbjct: 63 PSPRGK-GYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRH 121
Query: 1495 --------PRSRSPSSPELNNKCLTPQRERSGSESSVD-----------QKTVARTPLGQ 1535
+ R+P S E N + T + + + + D QK +
Sbjct: 122 REKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLE 181
Query: 1536 RSRSGSSQELDVKPSASPQE-RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594
+ +E+ +K SP+ RS+ SP + +++P R+ SSP+ S S+ R
Sbjct: 182 QENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRK-----SSPKSSSASK-KDR 235
Query: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDS--SPEPKAPAPR----------------ALPRRS 1636
++ + SSP + D+ R + QS +P P P P + ++
Sbjct: 236 KTSAVSSP-LLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKT 294
Query: 1637 RSGSS------------SKGRGPSPEGSS-STESSPEHPPKSRTARRGSRSSPEPKTKSR 1683
R G K R SP G S SS H S++ R SP P+ K R
Sbjct: 295 RDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRK-R 353
Query: 1684 TPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR 1743
TP +P L R A S + SSP+ R ++PPRHR E++ S
Sbjct: 354 TPSPSYQRTLTPPLRRSA--SPYPSHSLSSPQ-RKQSPPRHRSPMREKGRHDHERTSQSH 410
Query: 1744 RRRSASSPRTKTTSRRGR---SPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800
RR R T +R R S + +S SR R+ RDR + + RR
Sbjct: 411 DRRHER--REDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRR 468
Query: 1801 RQRSRSRSRVTRRRRGGSG--YHSRSPARQESSRTSS--RRRRGRSRT------PPTSRK 1850
R R +R R S SR P S+R + R R GR P SR
Sbjct: 469 ELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRS 528
Query: 1851 RSR-------SRTSPAPWKRSRSRASPATHR--RSRSRTPLISRRRSR-SRTSPVSRRRS 1900
R SRT R+ SR+ R RSR R P + + SR SR S + S
Sbjct: 529 YGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSS 588
Query: 1901 RSR---TSVTRRRSRSRAS-PVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRR 1956
S + TR R P R ++R RR R R + + P+ +
Sbjct: 589 NSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQ 648
Query: 1957 RSRSRTPPVTRRRSR------SRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRT 2010
RR R R R R R R R R R R R + R
Sbjct: 649 GRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELE 708
Query: 2011 SPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTR 2070
R R R R R R R R R+R R R R R R R +R R
Sbjct: 709 RERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERER 768
Query: 2071 SPPAIRRRS 2079
R R+
Sbjct: 769 ERERERERA 777
Score = 117 bits (293), Expect = 2e-25
Identities = 253/1178 (21%), Positives = 399/1178 (33%), Gaps = 201/1178 (17%)
Query: 1161 TAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAG--- 1217
T + +E+M ++D P ++ + S PV+ K++ R RE+
Sbjct: 82 TGDLRERMK-NKRQDVDTEPQKRNTEESSSPVR---------KESSRGRHREKEDIKITK 131
Query: 1218 -SSPETKEQNSALPTSSQDEELME-----VVEKSEEPAGQILSHLSSELKEMSTSNFESS 1271
+PE++E+N T+ D + + V E S E Q + EL ++ N E
Sbjct: 132 ERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQ---KIQRELMKLEQENMEKR 188
Query: 1272 PEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPL 1331
E+ + VS P + S P SP ++ S SP R++S S
Sbjct: 189 EEIIIKKEVS-----------------PEVVRSKLSP--SPSLRKSSKSPKRKSSPKS-- 227
Query: 1332 EFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAV 1391
SS K+D ++ D + K ++ G + P
Sbjct: 228 ----------------SSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIP 271
Query: 1392 EKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGS 1451
E + V D + E + +D + R +SP + S
Sbjct: 272 EDIALGKKYKEKYKVKDRI------EEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHS 325
Query: 1452 GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLT 1511
SRH S S G +PS R +P P + +T P R +SP ++ +
Sbjct: 326 PISSRHHSSSSQSGSSIQRHSPSPRRKR---TPSP-SYQRTLTPPLRRSASPYPSHSLSS 381
Query: 1512 PQRERSGSESSVDQKTVARTPLGQRSRSG---SSQELDVKPSASPQERSESDSSPDSKAK 1568
PQR++S R+P+ ++ R +SQ D + R + D DS+ +
Sbjct: 382 PQRKQSPPRH--------RSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREE 433
Query: 1569 TRTPLRQRS----RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
Q S R P D + R R +R R + + S + E
Sbjct: 434 REYEQDQSSSRDHRDDREPR-DGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKES 492
Query: 1625 KAPAPRALPRRSRSGSSSKGRGPS------PEGSSSTESSPEHPPKSRTARRGSRSSPEP 1678
+ P R + +GR PE S S + SRT R + S E
Sbjct: 493 RDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIR-NESRNES 551
Query: 1679 KTKSRTPPRRRSSRSSPELTRK-ARLSRRSRSASSSP--------ETRSRTPPRHRRSPS 1729
+++ R RS PEL K +R SR S+ S S ETRS P R R P
Sbjct: 552 RSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRY-PE 610
Query: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP---SPKPRGLQRSRSRSRREKTRTTR 1786
+ + A S RR + +R SP + L+R R R R
Sbjct: 611 RDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDD 670
Query: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS--RSPARQESSRTSSRRRRGRSRT 1844
RRD + R R R R R R R R R AR+ R R R R
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD 730
Query: 1845 PPTSRKRSRSRTSPAPWKRSRSRASPATHR-RSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
R+R R R +R R R R R R R R R R+R R R R
Sbjct: 731 RDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDW 790
Query: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR-----TPTTR---RRSRSRTPP--- 1952
+ R R R R+ R+S+ R +P+ R +R R +P
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDA 850
Query: 1953 -----------------VTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSP-VTRRRS 1994
V + SRS +P + R R+ R +S +
Sbjct: 851 YNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQEL 910
Query: 1995 RSRTSPVTRRRSRSRTSPVTRRRSRS----------RTPPAIRRRSRSRTPLLPRK-RSR 2043
+ + S V ++R ++ +R R++ T ++ + + + + +
Sbjct: 911 KEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKK 970
Query: 2044 SRSPLAIRRRSRSRT--------PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPA 2095
+ I R + T P+ + K+S+ + +R S SD S
Sbjct: 971 KEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEK------KRKKSKGDSDISDEEAAQQ 1024
Query: 2096 TRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGS 2155
++ G RTPP+ + + + G+LE ++ +
Sbjct: 1025 SKKKRGPRTPPITTKEELVEMCNGKN------------GILE---------DSQKKEDTA 1063
Query: 2156 MMDGPGPRIPDHQRTSVPE-NHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAP 2214
D +PD RT V E H + T L + PPP P
Sbjct: 1064 FSDWSDEDVPD--RTEVTEAEHTATATTPGSTPSPLSSLLPPPP---------------P 1106
Query: 2215 VPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPT 2252
V + T PA A+ AA++ + + + T A PT
Sbjct: 1107 VATATATTVPATLAATTAAAATSFSTSAITISTSATPT 1144
Score = 89.7 bits (221), Expect = 3e-17
Identities = 164/739 (22%), Positives = 251/739 (33%), Gaps = 95/739 (12%)
Query: 20 QRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVEL---RCLELEEM 76
+R + V RR ER + E R E +R D ER++ EL R E E
Sbjct: 662 ERRVDRVDDRRDERARERDRERERDRER---ERERERERDREREKERELERERARERERE 718
Query: 77 MEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLR 136
E++ E+ R E+D + E + + E++ ER R
Sbjct: 719 REKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERAR 778
Query: 137 AAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDR 196
+ D D R R K+ +RE + R ++K KK+ ++
Sbjct: 779 ERDKERERQRDWEDKDKGRDDRREKREE---------IREDRNPRDGHDERKSKKRYRNE 829
Query: 197 GRRSESSSPRRERKKS----------SKKKKHR--------SESESKKRKHRSPTPKSKR 238
G S SP+R R+ S K +KHR ES S H + + +
Sbjct: 830 GSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRW 889
Query: 239 KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS----DTSRSRS-----------RSAA 283
K +D+K +R S+ + + +S D ++SR R+ R +
Sbjct: 890 KEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETS 949
Query: 284 AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKK 343
+ H ++ + D E G T + K+ + K KK
Sbjct: 950 DRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKK 1009
Query: 344 EKS----ATRPSPSPERSSTGPEPPAPTPL--LAERHGGS---------PQPLATTPLSQ 388
K + + + GP P T L E G + A + S
Sbjct: 1010 SKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSD 1069
Query: 389 EPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPG 448
E V +E + + +P P SS PP P T + ++ + A A
Sbjct: 1070 EDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATS 1129
Query: 449 ---SHREISSSPTSKNRSHGRAKRDKSHSHTPSRRM------------GRSRSPATAKRG 493
S IS+S T N ++ + SH R+ + R P KR
Sbjct: 1130 FSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRS 1189
Query: 494 RSRSRTPTKRGHS--RSRSPQWRRSRSAQRWGRSRSPQRR-----GRSRSPQRPGWSRSR 546
S + R H+ R RSP + SA R G +S ++R R R + S
Sbjct: 1190 SSLGSNRSNRSHTSGRLRSPS---NDSAHRSGDDQSGRKRVLHSGSRDREKTK---SLEI 1243
Query: 547 NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS 606
+R+ R +RG + + R SRS + R R R + R + R
Sbjct: 1244 TGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERD 1303
Query: 607 RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666
R R R R R R+R R + R+R R R R R +R R R R
Sbjct: 1304 RYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKR-RDLDR---ER 1359
Query: 667 GRSRSRTPARRSGRSRSRT 685
R S + R R R RT
Sbjct: 1360 ERLISDSVERDRDRDRDRT 1378
Score = 83.6 bits (205), Expect = 3e-15
Identities = 227/1116 (20%), Positives = 381/1116 (34%), Gaps = 177/1116 (15%)
Query: 1089 KSQTSPKGGRSR-SSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPT 1147
K + SP+ RS+ S SP +S+SP R+ +SP KS + ++ R S SS P
Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRK------SSP--KSSSASKKDRKTSAVSS-PL 244
Query: 1148 VDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLR 1207
+D Q +T +SK+K P + PP +D + + + KD +
Sbjct: 245 LDQ-----QRNSKTNQSKKKGPRTP----SPPPPIPED----IALGKKYKEKYKVKDRIE 291
Query: 1208 TPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSN 1267
R+ G E + + P +S PAGQ S +SS S+ +
Sbjct: 292 EKTRDGKDRGRDFERQREKRDKP-------------RSTSPAGQHHSPISSRHHSSSSQS 338
Query: 1268 FESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSF 1327
S +R + S ++ S + + P S+ P S + SP R S
Sbjct: 339 GSSI----QRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRS- 393
Query: 1328 GSPLEFRNSGPLGTEMNTGFSS---EVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS 1384
R G E + E +ED G + ++ + ++ + S H
Sbjct: 394 ----PMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDD 449
Query: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRE-RSSSASSPEMKDGLPRTPSRRSRSGS 1443
D ++ + + D+ SRE R S + E +D PR SR +R
Sbjct: 450 REPRDGRDRRDARDTRD-RRELRDSRDMRDSREMRDYSRDTKESRD--PRD-SRSTRDAH 505
Query: 1444 SPGLRDGSGT-------PSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496
R+G T P G + ++ RT R S +S E + + R R
Sbjct: 506 DYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRN-DRMGRSR 564
Query: 1497 SRSPSSPELNNK-CLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555
R P PE ++ Q + S S+ R+ +R R D +S +
Sbjct: 565 GRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER 624
Query: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRR-----------SRSGSSPEV 1604
R D++ + + P G + E++ R RR +R
Sbjct: 625 RHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERE 684
Query: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664
+D+ R R + + + R R + R + E E
Sbjct: 685 RDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERD 744
Query: 1665 SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724
R R E + + R R R E R+ R R R + + R R
Sbjct: 745 REKEREREREERE-RERERERERERERERERERARE-RDKERERQRDWEDKDKGRDDRRE 802
Query: 1725 RRSPSVSSPEPAE-----KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR 1779
+R P + KS+ R + SPR RR SP + +
Sbjct: 803 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD----AYNSGDDKN 858
Query: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR------- 1832
EK R SQ + RS S S +T R+G R P R+ESSR
Sbjct: 859 EKHRLL--------SQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQEL 910
Query: 1833 ----TSSRRRRGRSRTPPTSRKRSRS----------RTSPAPWKRSRSRASPATHRRSRS 1878
+S ++R ++ +SR R++ TS ++ +A +
Sbjct: 911 KEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKK 970
Query: 1879 RTPLISRRRSRSRTSP-----VSRRRSRSRTSVTRRRSRSR---------ASPVSRRRSR 1924
+ + R T+ S ++ + + S+ ++R +S+ A+ S+++
Sbjct: 971 KEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRG 1030
Query: 1925 SRTPPVTRRR---------------------------------SRSRTPTTRRRSRSRTP 1951
RTPP+T + R+ + + TP
Sbjct: 1031 PRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTP 1090
Query: 1952 PVTRRRSRS---RTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS 2008
T S PPV + + + + + + TS T + S ++ T + +
Sbjct: 1091 GSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNT 1150
Query: 2009 RTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSL 2068
+ + R+ RT R + TP + + ++ R P+ +R S + G
Sbjct: 1151 FANEDSHRKCH-RT-----RVEKVETPHVTIEDAQHRKPMDQKRSS-------SLGSNRS 1197
Query: 2069 TRSPPAIRRRSASGSSSDRSRSATPPATR-NHSGSR 2103
RS + R RS S S+ RS R HSGSR
Sbjct: 1198 NRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSR 1233
Score = 68.6 bits (166), Expect = 8e-11
Identities = 70/241 (29%), Positives = 90/241 (37%), Gaps = 18/241 (7%)
Query: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS--DSEGSSLPVQPEVALKRVPS 2581
L P+ R SS S SS SSS+S +S SS D + +S Q + R PS
Sbjct: 206 LSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPS 265
Query: 2582 PTPAPKEAVREG-----------RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
P P E + G R E T + R S+S + S
Sbjct: 266 PPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHS 325
Query: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRS 2690
SS SSSS S SS P + P P+ + P RRS SP P SL S
Sbjct: 326 PISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASP-YPSHSL-SSPQ 383
Query: 2691 LSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
SP R P + D + +S R +R D+R KR RE S + +
Sbjct: 384 RKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRG---KRDREKDSREEREYEQDQ 440
Query: 2751 S 2751
S
Sbjct: 441 S 441
Score = 67.4 bits (163), Expect = 2e-10
Identities = 125/588 (21%), Positives = 209/588 (35%), Gaps = 38/588 (6%)
Query: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL 1533
S+ R + SP P+ P+ R R SP S N+ ++ R S+ Q++ + +P
Sbjct: 822 SKKRYRNEGSPSPRQSPK--RRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879
Query: 1534 G-QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLS 1592
R G +E D KP R + K + R+++ S + ++ +
Sbjct: 880 HLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIG 939
Query: 1593 PRRSRSGSSPEVKDKPRAAPRAQSGSDSSP-EPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651
+S E D+ + ++ P + K + R + +S G+ SP+
Sbjct: 940 HHQSEDR---ETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKK 996
Query: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711
+S + KS+ S ++K + PR +P +T K L +
Sbjct: 997 GQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPR------TPPITTKEELVEMCNGKN 1050
Query: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771
E + + + S S E R + T T + G +PSP L
Sbjct: 1051 GILEDSQK---KEDTAFSDWSDEDVPD-----RTEVTEAEHTATATTPGSTPSPLSSLLP 1102
Query: 1772 RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831
+ T + ++ +TS + T + + A ++S
Sbjct: 1103 PPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTF-----ANEDSH 1157
Query: 1832 RTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSR 1891
R R R + TP + + ++ R P KRS S S ++R S S R
Sbjct: 1158 RKCHRTRVEKVETPHVTIEDAQHR-KPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHR 1216
Query: 1892 TSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTP 1951
+ R R S +R R ++++ ++ R +SR + R T + R+ SRS
Sbjct: 1217 SGDDQSGRKRVLHSGSRDREKTKSLEITGER-KSRIDQLKRGEPSRSTSSDRQDSRSH-- 1273
Query: 1952 PVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRR--SRSR 2009
S R+ P + R+ SR+ R R R R TR+R R
Sbjct: 1274 ------SSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDA 1327
Query: 2010 TSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSR 2057
R R R R R R R + L R+R R S R R R R
Sbjct: 1328 DKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDR 1375
Score = 67.0 bits (162), Expect = 2e-10
Identities = 132/719 (18%), Positives = 238/719 (33%), Gaps = 77/719 (10%)
Query: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDR--GRRSESSSPR 206
SSF+ + R+ + +P S +R + +++++++ DR RR E + R
Sbjct: 620 SSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARER 679
Query: 207 -RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTS 265
RER++ ++++ R ++R+ + + + ++++R++ R R R
Sbjct: 680 DRERERDRERERERERERDREREKERELERERAREREREREKERD-------RERDRDRD 732
Query: 266 ADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPE 325
D + R R + + R E + +R + E
Sbjct: 733 HDRERERERERDREKEREREREE-------------RERERERERERERERERERERARE 779
Query: 326 T-ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATT 384
++ +EDKDK + ++ R +R+ + R+ GSP P +
Sbjct: 780 RDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKK-RYRNEGSPSP-RQS 837
Query: 385 PLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA 444
P + +P S+A + D K ES SP R E KP
Sbjct: 838 PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPE 897
Query: 445 PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG 504
S R K S DK T R R+ +S R + R
Sbjct: 898 RKESSRRYEEQELKEKVSSV-----DKQREQTEILESSRMRAQDIIGHHQSEDRETSDRA 952
Query: 505 HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS 564
H ++ + + ++ RG + G S ++ +S +R +S
Sbjct: 953 HDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKG 1012
Query: 565 RSPATRGRSRSRTPARRGRSRSRTPA-------------------RRRSRSRTPTRRRSR 605
S + + ++ +RG RTP + + T S
Sbjct: 1013 DSDISDEEAAQQSKKKRG---PRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSD 1069
Query: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
P R + + A + +P S P + + + PA + +
Sbjct: 1070 EDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATS 1129
Query: 666 RGRSR-----SRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720
S S TP + + + + R R+R + + + H + +
Sbjct: 1130 FSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEK---VETPHVTIEDAQHRKPMDQ 1186
Query: 721 RGRSGSSSERKNKSRTSQR-RSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSL 779
+ S S R N+S TS R RS SN S S R+ S R + K+
Sbjct: 1187 KRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKT-------- 1238
Query: 780 SGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSS 838
K T R+SR + SR+ + S S ++ S RQ HS S
Sbjct: 1239 -------KSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRS 1290
Score = 53.9 bits (128), Expect = 2e-06
Identities = 60/207 (28%), Positives = 87/207 (42%), Gaps = 30/207 (14%)
Query: 2564 EGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK-----RRSSSSSSSSSSSS 2618
E ++ + E+ +K+ SP E VR P+P+ RK +R SS SSS+S
Sbjct: 181 EQENMEKREEIIIKKEVSP-----EVVRSKL--SPSPSLRKSSKSPKRKSSPKSSSASKK 233
Query: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ--ALPKPASPKKPPPGERRSR 2676
+S+ SS +S ++ S +PSP P P+ AL K K + + R
Sbjct: 234 DRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKY----KVKDR 289
Query: 2677 SPRKPIDSLRDSRSLSYSPVERRRP-SPQPSPRDQQSSSSERGSRRGQRGDS---RSPSH 2732
K D R +R +P S P+ + SS S Q G S SPS
Sbjct: 290 IEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSP 349
Query: 2733 KRRRETPSPR-------PMRHRSSRSP 2752
+R+R TPSP P+R +S P
Sbjct: 350 RRKR-TPSPSYQRTLTPPLRRSASPYP 375
Score = 42.4 bits (98), Expect = 0.006
Identities = 51/233 (21%), Positives = 77/233 (33%), Gaps = 17/233 (7%)
Query: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585
PA + S SS SSSS S SS S S + S + P + P P+ +
Sbjct: 319 PAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHS 378
Query: 2586 PKEAVREGRPPEP-TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
R+ PP +P + K R +S S + S
Sbjct: 379 LSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQ 438
Query: 2645 SSSSPSPAKPGPQALPKPASPKKPPPG-ERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
SS + ++P G +RR + LRDSR + S R
Sbjct: 439 DQSSSRDHR----------DDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRD 488
Query: 2704 QPSPRDQQSSSSERGS-----RRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
RD + S S R + R G+ + ++ + +R SSR+
Sbjct: 489 TKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRT 541
Score = 41.2 bits (95), Expect = 0.014
Identities = 65/337 (19%), Positives = 134/337 (39%), Gaps = 34/337 (10%)
Query: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS----LSSGAVATT 2483
SSRM +Q ++ Q + R A + + Q P+ + + G + TT
Sbjct: 929 SSRMR---AQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETT 985
Query: 2484 TSSAGDHNGMLSVPAPGVPHSDVGEP-PASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542
+ +G + P G + + S G S A Q +K++R + ++
Sbjct: 986 SE-----DGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKE 1040
Query: 2543 ------SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV------ALKRVPSPTPAPKEAV 2590
+ + S ++ SD +P + EV A P TP+P ++
Sbjct: 1041 ELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSL 1100
Query: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
P P P ++ ++ +++++++++S S+S+ + S+S++ +++++++ ++ S
Sbjct: 1101 L----PPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDS 1156
Query: 2651 PAKPGPQALPKPASPKKP-PPGERRSRSPRKPIDSLRDSRS-LSYSPVERRRPSPQPSPR 2708
K + K +P + R +K SL +RS S++ R PS + R
Sbjct: 1157 HRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHR 1216
Query: 2709 DQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR 2745
S + G +R SR + E R R
Sbjct: 1217 ---SGDDQSGRKRVLHSGSRDREKTKSLEITGERKSR 1250
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 146 bits (369), Expect = 2e-34
Identities = 251/1270 (19%), Positives = 458/1270 (36%), Gaps = 162/1270 (12%)
Query: 111 TPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
T +P T ++ K + A S+ DP R + + PA
Sbjct: 90 TRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADST--- 146
Query: 171 YSLVRESSSSR--SPTPKQKKKKKKKDRG-----RRSESSSPRRERKKSSKKKKHRSESE 223
+ +ES+ + +P PK K +K G R+S+ + E+ S+ K S +
Sbjct: 147 -TTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHK 205
Query: 224 SKKRKHRSPTPKSKRKSKD------KKRKRSRSTTPAPKSRRA---HRSTSADSASSSDT 274
+ H S ++K+KS K + TT P+ R+T A + T
Sbjct: 206 TTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKT 265
Query: 275 SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334
+++ + +A T +LA P+ GR + S T + ++ E T P+ P
Sbjct: 266 TKNIQETISANELTQSLA--EPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEP 323
Query: 335 YEDKDKDKKEKSATRPS-PSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV-- 391
E++++ E +A P+ P+ R T E P HG TTP EP
Sbjct: 324 IENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEH 383
Query: 392 --------NPPSEASPTR--DRSPPKSPEKLPQSSSS-----------ESSPPSP-QPTK 429
PS A PT +R+P + + S+ S E++ PSP +PT+
Sbjct: 384 GERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTE 443
Query: 430 VSRHASSSPESPKPAPAPGSHREISS------SPTSKNRSHGRAKRDKSHSHTPSRRMGR 483
++ +P PA P +RE ++ SP + +K+
Sbjct: 444 NRERTANENTTPSPA-GPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENG 502
Query: 484 SRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS 543
R+P ++ S S PT+ G R+P + + + + +R ++ P
Sbjct: 503 QRTPFANEKTTSSSAEPTEHG---ERTPLANENTTPSPAEPTENRERTANEKTTPSP--- 556
Query: 544 RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603
+ T+ R+ A + S + T + RTP ++ S + RTP
Sbjct: 557 -AEPTENGDRTPLANEKTTPSLAEPT--ENGQRTPFANEKTTSSSAEPTEHEERTPLANE 613
Query: 604 SRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT- 662
+ + +PA +R RT + T SP + + + + PA +R RT
Sbjct: 614 NTTPSPAEPTENRERT--ANENTTPSPA---GPTENREMTANEKTTLFPAEPTENRERTA 668
Query: 663 -------PARRGRSRSRTP-ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH 714
PA + RTP A S S P G RTP + + S +
Sbjct: 669 NEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHG---ERTPLANENTTLSPAEPTENR 725
Query: 715 SRTPQRRGRSGSSSERKNKSRT-SQRRSRSNSSPEMKKSR---ISSRRSRSLSSPRSKAK 770
RT + + +N+ RT ++ + S + P R + + + SL+ P K
Sbjct: 726 ERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGK 785
Query: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
+ SS P + ++ P + + +S P + R + ++ P + ++
Sbjct: 786 RTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENR 845
Query: 831 SRQSHSSSSPHP--------------KVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
++ ++P P S P + +P ANE++
Sbjct: 846 ESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGE 905
Query: 877 PDPELKSRT------PSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSH 930
P +T P+ H +P + +TP R P+ KA SP + +
Sbjct: 906 RTPFTNEKTTPSSAEPTEH--GERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTE 963
Query: 931 SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYS-HSGSSSPDTKVKPETPPRQSH 989
G ++ + S P + +P +N + P S G + + K P +P +
Sbjct: 964 HGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTP-SPAEPTE 1022
Query: 990 SGSISPYPKVKA-QTPPGPSLSGSKSPCPQEKSKDSLVQSCP-GSLSLCAGVK-SSTPPG 1046
G +P K +P P+ +P E + S V+ G + A K + +P G
Sbjct: 1023 HGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEG 1082
Query: 1047 ESYFGVSSLQLKGQSQTS----PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSS 1102
+ G + + S +H T+SP + + S + S + + R+ S+
Sbjct: 1083 PTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRD-------RATSA 1135
Query: 1103 SPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETA 1162
+ +T A PI+ + A + ++ S+ +P +T
Sbjct: 1136 NVITP-APAEPIKHAKRTTLA--------HEKMTQVTEKSTEHPE------------KTT 1174
Query: 1163 ESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPET 1222
+ EK P++ S K PV ++P +L G++ T
Sbjct: 1175 STTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENL----------------GNTTLT 1218
Query: 1223 KEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSL 1282
E A S+++ E V K+ +P+ ++ S ++S+ + + P S
Sbjct: 1219 TETIKAPVKSTENPEKTAAVTKTIKPSVKVTGDKS---LTTTSSHLNKTEVTHQVPTGSF 1275
Query: 1283 TLDQSQSQAS 1292
TL S+++ S
Sbjct: 1276 TLITSRTKLS 1285
Score = 103 bits (258), Expect = 2e-21
Identities = 224/1226 (18%), Positives = 414/1226 (33%), Gaps = 148/1226 (12%)
Query: 1491 QTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVA-RTPLGQRSRSGSSQELDVKP 1549
Q P +S E C T + + + + + KT+ ++ +S+E
Sbjct: 69 QRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQ 128
Query: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609
P R++ P T + +P KS+++ R+S +G S +
Sbjct: 129 GKDPMIRNQRSVDPADSTTTHKESAGKKHITPAP----KSKINCRKSTTGKSTVTRK--- 181
Query: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTAR 1669
SD + P + L + S S + + S + + S P K A
Sbjct: 182 --------SDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAAS 233
Query: 1670 RGS-RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH--RR 1726
+ + +++ P+ +T R + S LT+ + + + SA+ ++ + P H R
Sbjct: 234 KTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAE-PTEHGGRT 292
Query: 1727 SPSVSSPEPAEKSRSSRRRRSAS---SPRTKTTSRR---GRSPSPKPRGLQRSRSRSRRE 1780
+ ++P PAE + + R + + SP +R + +P P G +R + E
Sbjct: 293 ANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANE 352
Query: 1781 KT-----RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG-----YHSRSPARQES 1830
T T +R+ + +T + + R S + R+P +
Sbjct: 353 NTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDK 412
Query: 1831 SRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS-- 1888
+ +SS P + + T+P+P + + +R A + S R +
Sbjct: 413 TTSSSAESTEHGERTPLANEN----TTPSPAEPTENRERTANENTTPSPAGPTENRETTA 468
Query: 1889 --RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946
++ SPV +R T+ ++ SP + RTP + + S T
Sbjct: 469 NEKTTLSPVEPTENRETTA----NEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGE 524
Query: 1947 RSRTPPVTRRRSRSRTPPVTRRR----SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVT 2002
R TP + S P R ++ SP + RT + + S P
Sbjct: 525 R--TPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTE 582
Query: 2003 RRR------SRSRTSPVTRRRSRSRTPPAIRRRSRSRT-PLLPRKRSRSRSPLAIRRRSR 2055
+ ++ +S RTP A + S P R+R+ + +
Sbjct: 583 NGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPT 642
Query: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
TA K +L + P R + + S PA +G RTP N S
Sbjct: 643 ENREMTANEKTTLFPAEPTENRERTANEKTTSS-----PAEPTENGQRTP--FANEKTTS 695
Query: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN 2175
+ P+ G PL + T +S + R + + T P
Sbjct: 696 SSAEPT----------EHGERTPLANENTTLSPAEPTENR------ERTANEKTTPFPAE 739
Query: 2176 HAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAAN----LASR 2231
++R A + A+P + LA + P + + P AN +S
Sbjct: 740 PTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSA 799
Query: 2232 IPAASAAAMNLASART---PAIPT-----AVNLADSRTPAAAAAM--NLASPRTAVAPSA 2281
P A LA+ T PA PT N ++ PA + A+ +T P+
Sbjct: 800 EPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAE 859
Query: 2282 VN-----LADPRTPTAPA--------VNLAGARTPAALAALSLTGSGTPPTAANYPSSSR 2328
A+ T +PA LA +T + A + G TP T SS
Sbjct: 860 PTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSA 919
Query: 2329 TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLS 2388
P P + T P + +A T + P G + S
Sbjct: 920 EPTEHGERT---PLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPS 976
Query: 2389 AYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPR 2448
+ E PL + + +P + T+ +PS + P+ ++
Sbjct: 977 SAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSP--AEPTEHGERTPSANEKT 1034
Query: 2449 SPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGE 2508
P P+ ++ + TP A + S T +H ++ + S G
Sbjct: 1035 IPSPAKPTEHE-----EMTPSANENTTPSPVKPT------EHGEKTTLANEKITLSPEG- 1082
Query: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568
P GA+ SA + P+ + + ++S + +SS++ S+ ++S +
Sbjct: 1083 -PTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANV---- 1137
Query: 2569 PVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628
TPAP E ++ + T A K + S+ ++S++ ++
Sbjct: 1138 -------------ITPAPAEPIKHAK--RTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTR 1182
Query: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKP 2654
+ + S + + ++P P KP
Sbjct: 1183 TPEKPTLYSEKTICTKGKNTPVPEKP 1208
Score = 101 bits (251), Expect = 1e-20
Identities = 219/1102 (19%), Positives = 376/1102 (34%), Gaps = 142/1102 (12%)
Query: 1059 GQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDR 1118
G S+T DH+S T + E + E+ S Q K P RS P + ++
Sbjct: 101 GNSKTI-DHKSSTDNHEAPPTSEENSSNQGKD---PMIRNQRSVDPADSTTTH---KESA 153
Query: 1119 GEFSASPMLKSGMSPEQSRF-------QSDSSSYPTVDSNSLLGQSRLETAESKEKMALP 1171
G+ +P KS ++ +S +SD + P S S L + T+ S K
Sbjct: 154 GKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDK----TSTSSHKTTTS 209
Query: 1172 PQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPT 1231
+ + K K + FP + S +K T TP S T
Sbjct: 210 FHNSGNS---QTKQKSTSFPEKITAASKTTYKTT-GTPEESEKTEDSRTTVASDKLLTKT 265
Query: 1232 SSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPA-VSLTLDQSQSQ 1290
+ +E + E ++ A + H E +T + E ER A + TL ++
Sbjct: 266 TKNIQETISANELTQSLA-EPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPI 324
Query: 1291 ASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSE 1350
+ E + A GP E++E++ + EN+ P E G NT S
Sbjct: 325 ENRERTANENTAPFPAGP---TENREMTAN---ENTTLFPAEPTEHGERTANENTTPSPA 378
Query: 1351 VKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAV 1410
+ N+ T + E R+ P A +K SS +S
Sbjct: 379 EPTEHGERTANENTTPSPAEPTEHGERT---------PFANDKTTSSSAESTEHG----- 424
Query: 1411 PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIP 1470
RTP +++ S E + RT + + + T +R + + + +
Sbjct: 425 ERTPLANENTTPSPAEPTENRERTANENTTPSPA------GPTENRETTANEKTTLSPVE 478
Query: 1471 RTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR 1530
T +R +++ K P P +P N E++ S S+ + R
Sbjct: 479 PTENR-----ETTANEKTTPSPAEPTENGQRTPFAN--------EKTTSSSAEPTEHGER 525
Query: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
TPL + + S E + E++ + ++ RTPL + S E +
Sbjct: 526 TPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQ 585
Query: 1591 LSP--RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
+P + SS E + P A +++P P A P +R ++++ PS
Sbjct: 586 RTPFANEKTTSSSAEPTEHEERTPLANE--NTTPSP------AEPTENRERTANENTTPS 637
Query: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP-ELTRKAR----L 1703
P G + + TA + P T++R + SSP E T +
Sbjct: 638 PAGPTEN--------REMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFA 689
Query: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT-----TSR 1758
+ ++ S+S+ P P + ++S EP E + ++ P T T+
Sbjct: 690 NEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTAN 749
Query: 1759 RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS 1818
+PSP R+ EKT T + + + + T +++ S S +
Sbjct: 750 ENTTPSPAQPTENGDRTPLANEKT-TPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERT 808
Query: 1819 GYHSRSPARQESSRTSSRRRRGRSRT-----PPTSRKRS--RSRTSPAPWKRSRSR---- 1867
+ + + T +R R +T PT + S +T+P P + + +R
Sbjct: 809 PLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTA 868
Query: 1868 -----ASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSR-SRASPVSRR 1921
SPA TPL + ++ SP + RT T ++ S A P
Sbjct: 869 NENTTLSPAEPTEHEEMTPLAN---EKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEH- 924
Query: 1922 RSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR-----------SRTPPVTRRRS 1970
RTP + SR T R T ++ TP
Sbjct: 925 --GERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTE 982
Query: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS 2030
+P+ + TSP RT+ ++ SP RTP A +
Sbjct: 983 NGERTPLA--NENTTTSPTESTEHGERTA-----NEKTTPSPAEPTEHGERTPSANEKTI 1035
Query: 2031 RSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRS------LTRSPPAIRRRSASGSS 2084
S P P + +P A + S T G+++ +T SP A +S
Sbjct: 1036 PS--PAKPTEH-EEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTS 1092
Query: 2085 SDRSRSATPPATRNHSGSRTPP 2106
++ + + H T P
Sbjct: 1093 ANEKITPSLAKPTEHGERTTSP 1114
Score = 90.9 bits (224), Expect = 2e-17
Identities = 215/1126 (19%), Positives = 393/1126 (34%), Gaps = 153/1126 (13%)
Query: 1685 PPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS-- 1742
PP S E R +R S+ + P S+T + + +P +E++ S+
Sbjct: 71 PPELPKSTEIHEQKRHCNTTRHSKP-TDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQG 129
Query: 1743 -----RRRRSASSPRTKTTSRRGRSP---SPKPRGLQRSRSRSRREKTRTTRRRDRSG-- 1792
R +RS + TT + +P P+ R +S K+ TR+ D++G
Sbjct: 130 KDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCR-KSTTGKSTVTRKSDKTGRP 188
Query: 1793 --SSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRK 1850
S ST + S ++ + G S +S + E +S+ + TP S K
Sbjct: 189 LEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEK 248
Query: 1851 RSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR 1910
SRT+ A K T + + + ++S P RT+
Sbjct: 249 TEDSRTTVASDKL-------LTKTTKNIQETISANELTQSLAEPTEHG---GRTA----N 294
Query: 1911 SRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970
+ SP +R RT + + +P +R RT + T P +
Sbjct: 295 ENNTPSPAEPTENRERTA----NENTTLSPAEPIENRERT-------ANENTAPFPAGPT 343
Query: 1971 RSRTSPITRRRSRSRTSPVTR--RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP-PAIR 2027
+R + P R + T+P T R + + TP PA
Sbjct: 344 ENREMTANENTTLFPAEPTEHGERTANENTTP----SPAEPTEHGERTANENTTPSPAEP 399
Query: 2028 RRSRSRTPLLPRKRSRS---------RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRR 2078
RTP K + S R+PLA + + TP A + R+
Sbjct: 400 TEHGERTPFANDKTTSSSAESTEHGERTPLA----NENTTPSPAEPTENRERTANENTTP 455
Query: 2079 SASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEP 2138
S +G + +R +A T + PV +R + + + +P+P + + G P
Sbjct: 456 SPAGPTENRETTANEKTTLS-------PVEPTENRETTANEKT-TPSPAEPTEN-GQRTP 506
Query: 2139 LGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPS 2198
+ +T S + G + + T P ++R A + A P +
Sbjct: 507 FANEKTTSSSAEPTE----HGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTEN 562
Query: 2199 MSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLAD 2258
LA + P + + P AN + +S+A RTP LA+
Sbjct: 563 GDRTPLANEKTTPSLAEPTENGQRTPFANEKT---TSSSAEPTEHEERTP-------LAN 612
Query: 2259 SRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPP 2318
T + A RTA + + A P N PA P
Sbjct: 613 ENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAE-----------PT 661
Query: 2319 TAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGA 2378
++ +T +PA G R+ A +T ++ A + R A
Sbjct: 662 ENRERTANEKTTSSPAEPTENGQRTP-------FANEKTTSSSAEPTEHGERTPLANENT 714
Query: 2379 NLTSPRVPLSAYERVSG-RTSP----PLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ 2433
L SP P ER + +T+P P +R R+ + PS ++ T +P +
Sbjct: 715 TL-SPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKT 773
Query: 2434 APSQSLLPPAQDQPRSPVPSAFSDQSRCLI---AQTTPVAGSQSLSSGAVATTTSSAGDH 2490
PS L P ++ R+P + + S A+ TP+A + SS A T +
Sbjct: 774 TPS--LAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTAN 831
Query: 2491 NGMLSVPAPGVPHSDVGEPPASTG------------AQQPSALAALQPAKERRSSSSSSS 2538
PA + + +T A + + L+ +P + + ++
Sbjct: 832 EKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANE 891
Query: 2539 SSSSSSSSSSSS-------SSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
++ S + + + + ++ S+ G P+ E+ PT +
Sbjct: 892 KTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIAN 951
Query: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSSS 2645
E P P ++ + ++ SS+ + + ++ ++++S + S+ +++
Sbjct: 952 EKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANE 1011
Query: 2646 SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP-Q 2704
++PSPA+P P++ +K P SP KP + ++ S E PSP +
Sbjct: 1012 KTTPSPAEPTEHGERTPSANEKTIP------SPAKP----TEHEEMTPSANENTTPSPVK 1061
Query: 2705 PSPRDQQSSSSERG---SRRGQRGDSRSPSHKRRRETPS-PRPMRH 2746
P+ ++++ + S G + + TPS +P H
Sbjct: 1062 PTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEH 1107
Score = 42.4 bits (98), Expect = 0.006
Identities = 34/220 (15%), Positives = 80/220 (36%), Gaps = 14/220 (6%)
Query: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
+++ S + + + ++ ++S S+ S G P+ E PT +
Sbjct: 391 NTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTAN 450
Query: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
E P P R ++++ ++ S + + ++++ ++ S + + + + +
Sbjct: 451 ENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANE 510
Query: 2652 AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711
A P + P E + SP +P ++ + + E+ PSP
Sbjct: 511 KTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTAN------EKTTPSP-------- 556
Query: 2712 SSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
+ +E G R + +PS E P + + S
Sbjct: 557 AEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTS 596
Score = 42.0 bits (97), Expect = 0.008
Identities = 60/396 (15%), Positives = 145/396 (36%), Gaps = 36/396 (9%)
Query: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER---APSPSSRMGQAPS---QSL 2439
P ++ E S + P++ RS P + + + ++ + P+P S++ S +S
Sbjct: 118 PPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKST 177
Query: 2440 LPPAQDQPRSPVPSAFSDQSRCLIAQ---TTPVAGSQSLSSGAVATTTSSAGDHNGMLSV 2496
+ D+ P+ + S + + TT S + + +T+ +
Sbjct: 178 VTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTY 237
Query: 2497 PAPGVPH-SDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
G P S+ E +T A + +E S++ + S + + +++ ++
Sbjct: 238 KTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENN 297
Query: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS- 2614
+ S + +E L P + E P P R +++ +++
Sbjct: 298 TPSPAEPTENRERTANENTTLSPA-EPIENRERTANENTAPFPAGPTENREMTANENTTL 356
Query: 2615 ---SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK---- 2667
+ +++ +++ S + + +++ +++PSPA+P P + K
Sbjct: 357 FPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSS 416
Query: 2668 -----------PPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSE 2716
P E + SP +P ++ + + E PSP +++++++E
Sbjct: 417 SAESTEHGERTPLANENTTPSPAEPTENRERTAN------ENTTPSPAGPTENRETTANE 470
Query: 2717 RGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
+ + + + TPSP R+P
Sbjct: 471 KTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTP 506
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 145 bits (367), Expect = 4e-34
Identities = 162/543 (29%), Positives = 230/543 (42%), Gaps = 69/543 (12%)
Query: 176 ESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS-KKKKHRSESESKKRKHRSPTP 234
E+ S R + +K E S + + K S KKKKH+ S+ KK KH S
Sbjct: 5 ETQSLREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEED 64
Query: 235 KSKR---KSKDKKRKRSRSTTPAPKSRR--AHRSTSADSASSSDTSRSRSRSAAAKTHTT 289
K K+ K K KK KR + K A R+ D A D + R+ A+
Sbjct: 65 KDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRAL-IKAELDNE 123
Query: 290 ALAGRSPSPA--------SGRRGEGDA-PFSEPGTTSTQRPSSPETATKQPSSPYEDKDK 340
+ G+ S SG EG+ + G S+ R SS + + + K +
Sbjct: 124 LMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKR 183
Query: 341 DK-KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASP 399
K + K TR ++S G E ++ E+ S ++ PS+ S
Sbjct: 184 SKSRSKERTRHRSDKKKSKGGIE------IVKEKTTRSKSK------ERKKSKSPSKRSK 231
Query: 400 TRDRS-PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT 458
++D++ KSP +S SP KV S + K +P
Sbjct: 232 SQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPI-----------I 280
Query: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518
+++RS R K+ +S P G+S+ +R RS+ R + + + P S+
Sbjct: 281 NESRSRDRGKKSRS----PVDLRGKSKD----RRSRSKERKSKRSETDKEKKPIKSPSKD 332
Query: 519 AQRWGRSRSPQRRGRSRSPQRPGWS-RSRNTQRRGRSRSARRGRS-HSRSPATRGRSRSR 576
A +RSP RR RSP+R S + R+ RR RS RS S+SP SR+
Sbjct: 333 ASSGKENRSPSRRP-GRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSP-----SRTL 386
Query: 577 TPARRGRSRS-----RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARR----RSRT 627
+P RR +SRS R P RRR S R R R +RR RS+ +P R R R+
Sbjct: 387 SPGRRAKSRSLERKRREPERRRLSS---PRTRPRDDILSRRERSKDASPINRWSPTRRRS 443
Query: 628 RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687
RSP+RRRSRS RS R RSR+P RR R R R RSRSR RR RS+ +
Sbjct: 444 RSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDK 503
Query: 688 RRG 690
+G
Sbjct: 504 FKG 506
Score = 129 bits (324), Expect = 4e-29
Identities = 151/520 (29%), Positives = 220/520 (42%), Gaps = 65/520 (12%)
Query: 174 VRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPT 233
+ +++S +S + + + + + + S + + + KK KH SE E K +KH
Sbjct: 15 MEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSE-EDKDKKH---- 69
Query: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
K K K K KRK + A R+ D A D + R+ A+ + G
Sbjct: 70 -KHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRA-LIKAELDNELMEG 127
Query: 294 RSPSP--------ASGRRGEGDA-PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDK-K 343
+ S SG EG+ + G S+ R SS + + + K + K +
Sbjct: 128 KVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSR 187
Query: 344 EKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDR 403
K TR ++S G E ++ E+ S ++ PS+ S ++D+
Sbjct: 188 SKERTRHRSDKKKSKGGIE------IVKEKTTRSKSK------ERKKSKSPSKRSKSQDQ 235
Query: 404 S-PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNR 462
+ KSP +S SP KV S + K +P R S++
Sbjct: 236 ARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSP 295
Query: 463 SHGRAKRDKSHSHTPSRRMGRS---------RSP----ATAKRGRSRSRTPTKRGHSRSR 509
R K S + R+ RS +SP ++ K RS SR P + RS
Sbjct: 296 VDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSL 355
Query: 510 SPQWR-RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGR---SHSR 565
SP+ R +SR RSRSP R RS Q SR+ + RR +SRS R R R
Sbjct: 356 SPKPRDKSR------RSRSPLLNDR-RSKQSKSPSRTLSPGRRAKSRSLERKRREPERRR 408
Query: 566 SPATRGRSRSRTPARRGRSRSRTPARR----RSRSRTPTRRRSRSRTPARRGRS---RSR 618
+ R R R +RR RS+ +P R R RSR+P RRRSRS P RR RS RSR
Sbjct: 409 LSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRS--PLRRSRSPRRRSR 466
Query: 619 TPAR--RRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656
+P R R R+RS +RRRSRSR RR RS+ + +G
Sbjct: 467 SPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKG 506
Score = 127 bits (320), Expect = 1e-28
Identities = 150/536 (27%), Positives = 230/536 (42%), Gaps = 58/536 (10%)
Query: 1512 PQRERSGSESSVDQKT-VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTR 1570
P+ E + SE S++++ Q S ++ S + + S+ D K K +
Sbjct: 13 PEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHK 72
Query: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD--KPRAAPRAQSGSDSSPEPKAPA 1628
++ R D + +R++ ++D K RA +A+ ++
Sbjct: 73 HKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSG 132
Query: 1629 PRALPRRSRSGSSSKGR--------GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT 1680
+ + SGS +G S SSST+ E T ++ S+S + +T
Sbjct: 133 MGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERT 192
Query: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
+ R+ ++ + R + R S SP RS++ + R+S S P + R
Sbjct: 193 RHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKS-----PTLRRR 247
Query: 1741 SSRRRRSASSPRTKTTSRRGRSPSP---KPRGLQRSRSRSRREKTRT-TRRRDRSGSSQS 1796
S + A SP +S S K + SRSR R +K+R+ R +S +S
Sbjct: 248 SQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRS 307
Query: 1797 TSRRRQRSRSRSRVTRR------RRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRK 1850
S+ R+ RS + ++ + SG +RSP SR R + RS +P K
Sbjct: 308 RSKERKSKRSETDKEKKPIKSPSKDASSGKENRSP-----SRRPGRSPKRRSLSPKPRDK 362
Query: 1851 RSRSRTSPAPWKRSRSRASPATH----RRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSV 1906
RSR+ +RS+ SP+ RR++SR+ + R+R +S R+R R +
Sbjct: 363 SRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRS--LERKRREPERRRLSSPRTRPRDDI 420
Query: 1907 TRRRSRSR-ASPVSR---RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
RR RS+ ASP++R R RSR+P RRRSRS RRSRS RRRSRS
Sbjct: 421 LSRRERSKDASPINRWSPTRRRSRSP--IRRRSRSPL----RRSRS-----PRRRSRSPR 469
Query: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2018
RRSRSR RRRSRSR RRRSRS+ + S S V + S
Sbjct: 470 RRDRGRRSRSRL----RRRSRSRGG--RRRRSRSKVKEDKFKGSLSEGMKVEQESS 519
Score = 120 bits (300), Expect = 2e-26
Identities = 125/391 (31%), Positives = 184/391 (47%), Gaps = 62/391 (15%)
Query: 1727 SPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTR 1786
S S E EK+R+ R SS R+ +T + K +RS+SRS+ +
Sbjct: 142 SGSEEEGEIHEKARNGNR----SSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSD 197
Query: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP 1846
++ G + + RS+S+ R S+SP+++ S+ +R+ + P
Sbjct: 198 KKKSKGGIEIVKEKTTRSKSKERKK----------SKSPSKRSKSQDQARKSKS-----P 242
Query: 1847 TSRKRSRSRTSPAPWKRS-RSRASPATHRRSRSRTPLISRRRSRSR----TSPVSRR-RS 1900
T R+RS+ + A + + + + R ++P+I+ RSR R SPV R +S
Sbjct: 243 TLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKS 302
Query: 1901 RSRTSVTRRRSRSRASPVSRRRSRSRTPPVT-----RRRSRSRTPTTRRRSRSRTPPVTR 1955
+ R S ++ R +S+ S + + ++P RS SR P + RS +P
Sbjct: 303 KDRRSRSKER-KSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRD 361
Query: 1956 RRSRSRTPPVTRRRSRSRTSPITRRRSRSRT-SPVTRRRSRS----RTSPVTRRRSRSRT 2010
+ RSR+P + RRS+ SP SRT SP R +SRS R P RR S RT
Sbjct: 362 KSRRSRSPLLNDRRSKQSKSP-------SRTLSPGRRAKSRSLERKRREPERRRLSSPRT 414
Query: 2011 SP---VTRRRSRSRTPPAIRR----RSRSRTPLLPRKRSRSRSPLAIRR--RSRSRTPRT 2061
P + RR RS+ I R R RSR+P+ R RSRSPL R R RSR+PR
Sbjct: 415 RPRDDILSRRERSKDASPINRWSPTRRRSRSPI----RRRSRSPLRRSRSPRRRSRSPRR 470
Query: 2062 A-RGKRSLTRSPPAIRRRSAS-GSSSDRSRS 2090
RG+RS +R +RRRS S G RSRS
Sbjct: 471 RDRGRRSRSR----LRRRSRSRGGRRRRSRS 497
Score = 104 bits (260), Expect = 1e-21
Identities = 118/452 (26%), Positives = 203/452 (44%), Gaps = 60/452 (13%)
Query: 505 HSRSRSPQWRRSRSAQRWGRSR------SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR 558
H ++R+ +RS+ G+ + ++R +SRS +R T+ R + ++
Sbjct: 151 HEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKER--------TRHRSDKKKSK 202
Query: 559 RGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR 618
G + TR +S+ R ++ RS++ + R +S++PT RR R+ + G++RS
Sbjct: 203 GGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQAR-KSKSPTLRR---RSQEKIGKARSP 258
Query: 619 TP--------ARRRSRTRSPVRRRSRSR-------SPARRSGRSRSRTPARRGRSRSRTP 663
T ++ + R +SP+ SRSR SP G+S+ R + R R+
Sbjct: 259 TDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSE 318
Query: 664 ARRGRSRSRTPAR-----RSGRSRSRTPARRGRSRSRTP----RRGRSRSRSLVRRGRSH 714
+ + ++P++ + RS SR P R + RS +P + RSRS L R
Sbjct: 319 TDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQ 378
Query: 715 SRTPQRR---GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL-SSPRSK-A 769
S++P R GR S + K R +RR R +S + I SRR RS +SP ++ +
Sbjct: 379 SKSPSRTLSPGRRAKSRSLERKRREPERR-RLSSPRTRPRDDILSRRERSKDASPINRWS 437
Query: 770 KSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKA-KSRTP-PRRSRSSSSPPPKQKS 827
+R R + S P ++S++P RRSRS + + +SR+ RRSRS + +S
Sbjct: 438 PTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRS 497
Query: 828 KTPSRQSHSSSSPHPKV--KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRT 885
K + S S KV +S + + +E+++ QRR + ++
Sbjct: 498 KVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRI--------QRQAIV 549
Query: 886 PSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP 917
+ S V S QS +R+ SP P
Sbjct: 550 QKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSP 581
Score = 104 bits (259), Expect = 1e-21
Identities = 103/352 (29%), Positives = 159/352 (45%), Gaps = 30/352 (8%)
Query: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQ----RSRSGSSQELDVKPSASPQERSESD 1560
++NK T +R +S S+ ++ + G + ++ S+ + K S SP +RS+S
Sbjct: 174 VDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQ 233
Query: 1561 SSPDSKAKTRTP-LRQRSRS----GSSP-----EVDSKSRLSPRRSRSGSSPEVKDKPRA 1610
D K+++P LR+RS+ SP +++ KS+ S R +S E + + R
Sbjct: 234 ---DQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSK-SKDRKKSPIINESRSRDRG 289
Query: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670
+++S D + K R+ R+S+ + K + P S S E+ SR R
Sbjct: 290 K-KSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGR 348
Query: 1671 GSRS---SPEPKTKSRTP--PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR 1725
+ SP+P+ KSR P RS + LS R+ S S E + R P R R
Sbjct: 349 SPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRR 408
Query: 1726 RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTT 1785
S + P SR R + ++ R T RR RSP + RSRS R ++R+
Sbjct: 409 LSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSP 468
Query: 1786 RRRDRSGSSQSTSRRRQRS------RSRSRVTRRRRGGSGYHSRSPARQESS 1831
RRRDR S+S RRR RS RSRS+V + GS ++ SS
Sbjct: 469 RRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSS 520
Score = 86.7 bits (213), Expect = 3e-16
Identities = 107/475 (22%), Positives = 181/475 (38%), Gaps = 67/475 (14%)
Query: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
++S PE + + E +++ SR ++ R+K + S K
Sbjct: 6 TQSLREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDK 65
Query: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR-----------RQRSRSRSRVTRRRR 1815
+ + + ++ D+ G S + + +QR+ ++ +
Sbjct: 66 DKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELM 125
Query: 1816 GGS----------GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR 1865
G GY S S E + R +R+ T K KRS+
Sbjct: 126 EGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSK 185
Query: 1866 SRASPATHRRSRSRTP-----LISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR 1920
SR+ T RS + ++ + +RS++ + +S S+ S ++ ++R SP R
Sbjct: 186 SRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLR 245
Query: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR 1980
RRS+ + ++R+PT + + ++ + R ++P + RSR R
Sbjct: 246 RRSQEKI-------GKARSPTD---DKVKIEDKSKSKDRKKSPIINESRSRDRGK----- 290
Query: 1981 RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAI---RRRSRSRTP-L 2036
+SR+ R +S+ R S R+S+ + ++ +S + A RS SR P
Sbjct: 291 --KSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGR 348
Query: 2037 LPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPAT 2096
P++RS S P RRSRS R K+S + S R A S +R R P
Sbjct: 349 SPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRRE--PER 406
Query: 2097 RNHSGSRTPP------------VALNSSRMSCFSRPSMSP------TPLDRCRSP 2133
R S RT P A +R S R S SP +PL R RSP
Sbjct: 407 RRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSP 461
Score = 75.1 bits (183), Expect = 9e-13
Identities = 106/439 (24%), Positives = 167/439 (38%), Gaps = 65/439 (14%)
Query: 1379 SGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438
+G+ SS S K + N+ + + + +R RS S K G+ +
Sbjct: 156 NGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKS---KGGIEIVKEKT 212
Query: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSR 1498
+RS S R S +PS+ S S P R + + + P +S+
Sbjct: 213 TRSKSKE--RKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSK 270
Query: 1499 SPS---SPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ-ELDVKPSASPQ 1554
S SP +N + ++S S + K+ R + +S S+ + + KP SP
Sbjct: 271 SKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPS 330
Query: 1555 ERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR------LSPRRSRSGSSPEVKDKP 1608
+ ++ S ++++ +R P R R SP+ KSR L+ RRS+ SP P
Sbjct: 331 K--DASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSP 388
Query: 1609 RAAPRAQSGSDSSPEP---KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665
+++S EP + +PR PR + + SP S P
Sbjct: 389 GRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIR 448
Query: 1666 RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR 1725
R +R R S P+ +SR+P RR R S ++RL RRSRS RSR+ +
Sbjct: 449 RRSRSPLRRSRSPRRRSRSPRRRDRGRRS-----RSRLRRRSRSRGGR-RRRSRSKVKED 502
Query: 1726 R-SPSVSSPEPAEKSRSS---------------------RRRRSA--------------- 1748
+ S+S E+ SS R +R A
Sbjct: 503 KFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMS 562
Query: 1749 --SSPRTKTTSRRGRSPSP 1765
S P + +S R RSPSP
Sbjct: 563 VPSEPSSPQSSTRTRSPSP 581
Score = 74.3 bits (181), Expect = 2e-12
Identities = 132/637 (20%), Positives = 240/637 (37%), Gaps = 54/637 (8%)
Query: 677 RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGR-SHSRTPQRRGRSGSSSERKNKS- 734
+S SR ++ + RS+ + S ++ + H +R +S+++ S
Sbjct: 35 QSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEGMSP 94
Query: 735 --RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792
RT E +++ I + L + ++ L L+ SGS ++
Sbjct: 95 AKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGS-----EEEGE 149
Query: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852
++R+G+ S T + + K++SK+ S++ S K K G +
Sbjct: 150 IHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVK 209
Query: 853 GSITSPQANEQ--SVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPR-QSP 909
T ++ E+ S +P +RS S D KS++P+ S + +S T + +
Sbjct: 210 EKTTRSKSKERKKSKSPSKRS---KSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIE 266
Query: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCS-----NVESRLL 964
+S S K II+ + G S SP + ++ RRSRS S + E + +
Sbjct: 267 DKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPI 326
Query: 965 PRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDS 1024
S SS + + P R S+SP P+ K++ P L+ +S ++SK
Sbjct: 327 KSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRS----KQSKSP 382
Query: 1025 LVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP 1084
PG + ++ E S S RS +SP R S +
Sbjct: 383 SRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRR 442
Query: 1085 SLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSS 1144
S +S + + RS SP SRSP R+DRG S S + + S R +S S
Sbjct: 443 S-RSPIRRRSRSPLRRSRSP--RRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKV 499
Query: 1145 YPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKD 1204
SL ++E S + D F V++ E +L+ +
Sbjct: 500 KEDKFKGSLSEGMKVEQESSSD------------------DNLEDFDVEEEDEEALIEQR 541
Query: 1205 TLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMS 1264
+ +R + ++S + S+ IL +++++KE
Sbjct: 542 RI-----QRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYE 596
Query: 1265 TSN---FESSPEVEERPAVSLTLDQSQSQASLEAVEV 1298
N FE+S + + +++ + SQ L A ++
Sbjct: 597 RENVDTFEASVKAKHN-LMTVEQNNGSSQKKLLAPDM 632
Score = 67.8 bits (164), Expect = 1e-10
Identities = 98/417 (23%), Positives = 156/417 (37%), Gaps = 55/417 (13%)
Query: 1285 DQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNS-------- 1336
D+ +S+ +E V+ + S S + S S + SP R S
Sbjct: 197 DKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKAR 256
Query: 1337 GPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGM 1396
P ++ S+ K+ P +N+ + G S S K+
Sbjct: 257 SPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKR 316
Query: 1397 SSNQSISSPVLDAVPRTPSRERSSSAS--SPEMKDGLPRTPSRRS---------RSGSSP 1445
S P+ ++PS++ SS SP + G R+P RRS R SP
Sbjct: 317 SETDKEKKPI-----KSPSKDASSGKENRSPSRRPG--RSPKRRSLSPKPRDKSRRSRSP 369
Query: 1446 GLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPEL 1505
L D S+ SPG + R+ R R E PE + L +PR R R
Sbjct: 370 LLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRRE----PERRRL-SSPRTRPRDD----- 419
Query: 1506 NNKCLTPQRERSGSESSVDQ----KTVARTPLGQRSRSGSSQELDVKPSASPQERSESDS 1561
+ +RERS S +++ + +R+P+ +RSRS ++ S SP+ RS S
Sbjct: 420 ----ILSRRERSKDASPINRWSPTRRRSRSPIRRRSRS------PLRRSRSPRRRSRSPR 469
Query: 1562 SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSS 1621
D ++R+ LR+RSRS S+S++ + + S +K + ++
Sbjct: 470 RRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDV 529
Query: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEP 1678
E A R R K + + + + S S P P S R SP P
Sbjct: 530 EEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTR-----SPSP 581
Score = 61.6 bits (148), Expect = 1e-08
Identities = 74/259 (28%), Positives = 95/259 (36%), Gaps = 40/259 (15%)
Query: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK-RVPSPTPA 2585
+KER+ S S S S S + S S + S + S P +V ++ + S
Sbjct: 217 SKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARS-PTDDKVKIEDKSKSKDRK 275
Query: 2586 PKEAVREGRPPEPTPAKRKR---RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
+ E R + R R S S S S S + S S +SS
Sbjct: 276 KSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASS 335
Query: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP----RKPIDSLRDSRSLS------ 2692
+ SPS +PG + SPK P RRSRSP R+ S SR+LS
Sbjct: 336 GKENRSPS-RRPGRSPKRRSLSPK-PRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAK 393
Query: 2693 --------YSPVERRRPSPQPSPRDQQSSSSERG-----------SRRGQRGDSRSPSHK 2733
P RR SP+ PRD S ER +RR R R S
Sbjct: 394 SRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRS 453
Query: 2734 RRRETPSPRPMRHRSSRSP 2752
R + SPR R SRSP
Sbjct: 454 PLRRSRSPR----RRSRSP 468
Score = 57.4 bits (137), Expect = 2e-07
Identities = 68/325 (20%), Positives = 118/325 (36%), Gaps = 29/325 (8%)
Query: 27 RGRRGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQ 86
+ R ER ++ +++ + +VK ERK+ + + ++Q
Sbjct: 185 KSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKS--------KSPSKRSKSQDQA 236
Query: 87 IQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV 146
+ K T R EK GK +P T ++ +K + R I +
Sbjct: 237 RKSKSPTLRRRSQEKI----GKARSP--------TDDKVKIEDKSKSKDRKKSPIIN--- 281
Query: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKK--KKKKKDRGRRSESSS 204
+ S D +++R + S +E S RS T K+KK K KD E+ S
Sbjct: 282 ESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRS 341
Query: 205 PRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST 264
P R +S K++ + K R+ RSP +R + K R+ S KSR R
Sbjct: 342 PSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKR 401
Query: 265 SADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSP 324
+ R+R R + + S R +P + +R SP
Sbjct: 402 REPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSP 461
Query: 325 ETATKQPSSPYEDKDKDKKEKSATR 349
++ P +D+ ++ +S R
Sbjct: 462 RRRSRSP----RRRDRGRRSRSRLR 482
Score = 57.0 bits (136), Expect = 3e-07
Identities = 63/230 (27%), Positives = 83/230 (36%), Gaps = 18/230 (7%)
Query: 2527 AKER---RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
+KER RS S ++ S S S S S+ S Q ++ SPT
Sbjct: 188 SKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQA----RKSKSPT 243
Query: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
+ + G+ PT K K S S S + S S S S S
Sbjct: 244 LRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSK 303
Query: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGE----RRSRSPRKPIDSLRDSRSLSYSPVERR 2699
S K K P K P + + +RSP + RSLS P ++
Sbjct: 304 DRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKS 363
Query: 2700 RPSPQPSPRDQQSSSSERGSRR---GQRGDSRSPSHKR----RRETPSPR 2742
R S P D++S S+ SR G+R SRS KR RR SPR
Sbjct: 364 RRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPR 413
Score = 55.1 bits (131), Expect = 1e-06
Identities = 63/240 (26%), Positives = 89/240 (37%), Gaps = 16/240 (6%)
Query: 2527 AKERRSS---SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
+K+R+ S + S S S S S S E S + + K + SP+
Sbjct: 271 SKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPS 330
Query: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS----SSSSSSSSSSSSSSSSS 2639
+E R P P + +R S S S S S S S S S + S
Sbjct: 331 KDASSG-KENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPG 389
Query: 2640 SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP-RKPIDSLRDSRSLSYSPVER 2698
+ S S +P + L P + + RR RS PI+ +R S SP+ R
Sbjct: 390 RRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRR 449
Query: 2699 RRPSP-----QPSPRDQQSSSSERG--SRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
R SP P R + +RG SR R SRS +RRR + + + S S
Sbjct: 450 RSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLS 509
Score = 45.4 bits (106), Expect = 8e-04
Identities = 40/162 (24%), Positives = 59/162 (36%), Gaps = 13/162 (8%)
Query: 2604 KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA 2663
K+RS S S + S S ++ S S S SPS K
Sbjct: 181 KKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSK 240
Query: 2664 SPKKPPPGERRSRSPRKP------IDSLRDSRSLSYSPV-----ERRRPSPQPSPRDQQS 2712
SP + + R P I+ S+ SP+ R R SP D +
Sbjct: 241 SPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRG 300
Query: 2713 SSSERGSRRGQRGDSRSPSHKRRR--ETPSPRPMRHRSSRSP 2752
S +R SR +R RS + K ++ ++PS + +RSP
Sbjct: 301 KSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSP 342
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 144 bits (363), Expect = 1e-33
Identities = 280/1107 (25%), Positives = 394/1107 (35%), Gaps = 181/1107 (16%)
Query: 1599 GSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS 1658
G++ V KP A G + PE APRA P RS +G+SS+ P S E +
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPES---APRAGPTRS-AGTSSRNPASRPPASGRGERA 103
Query: 1659 PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718
P P K+ + S T P ++ R S E T ++R + + S
Sbjct: 104 P--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET----VARGKATEAPKRSALS 157
Query: 1719 RTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR-GLQRSRSRS 1777
R P+ +P PA RS PR S R R P+ PR + + S
Sbjct: 158 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHS 216
Query: 1778 RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
E + RRR +G R S S + ++ SPAR S + R
Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS------------SPARSGPSARGTPR 264
Query: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV-S 1896
P + + P R A+PA S S PL + S ++ PV
Sbjct: 265 APAH---PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPSPSGTKARPVPP 319
Query: 1897 RRRSRSRTSVTRRRSRSRASPVS-RRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTR 1955
+ + T S A+P+ S S P + S TP ++ TPP+
Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379
Query: 1956 RRSRSRTPPV------TRRRSRSRTSPITRRRSRSRTS--PVTRRRSRSRTSPVTRRRSR 2007
S PP+ T ++ SP+ ++ TS T + + S + R+
Sbjct: 380 PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQA 439
Query: 2008 SRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRS 2067
S TSP + +PP S +P L S + SPL S T + S
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL-----SSPLTIHPLQALSS 494
Query: 2068 LTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPL 2127
L P S + S PP+ +TPP +L + + + PS++P PL
Sbjct: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSL------QTPPASLTTPPLE--NLPSLAPPPL 546
Query: 2128 DRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALA--- 2184
+P L + P QA S + P P P T P Q+ ALA
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP----QAPPALASPP 602
Query: 2185 ---LTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMN 2241
L + L PP + LA Q P P P S +P A + + P A A +
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLL 661
Query: 2242 LASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGAR 2301
A P P P A ASP V+PSA TP + A
Sbjct: 662 QAPFSPPPSP----------PVQAPFSPPASP--PVSPSA-------TPPSQA------- 695
Query: 2302 TPAALAALSLTGSGTPPTAANY-PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAA 2360
P +LAA L +PP + PS++ PQAP A P+ + S
Sbjct: 696 -PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL---------AAPPLQVPPS----- 740
Query: 2361 LAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMT 2420
PAS P +S + PRV PPLL + PPS P+ M+
Sbjct: 741 -PPAS-------PPMSPSATPPPRV-------------PPLLAAPPLQVPPSPPASLPMS 779
Query: 2421 SERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480
P P QAP PP Q P SP P++F Q+ P + S SL +
Sbjct: 780 PLAKPPP-----QAPPALATPPLQALP-SP-PASFPGQA--------PFSPSASLPMSPL 824
Query: 2481 ATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPS------------------ALA 2522
AT A +L+ P VP S PPAS Q P ALA
Sbjct: 825 ATPPPQAPP---VLAAPLLQVPPS----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877
Query: 2523 ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582
P RS SS+ S + SSS++S+ S EG + P A P
Sbjct: 878 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937
Query: 2583 T-----PAPKEAVREGRPPEPTPAKRKRRSSS---------SSSSSSSSSSSSSSSSSSS 2628
PAP A R G P P P S + S++ + + S
Sbjct: 938 AAWSRGPAPPLAFR-GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 996
Query: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
+S +++ + + +SS SP A+ G
Sbjct: 997 PGTSGGKAAAGAGAGASSRSPKQARLG 1023
Score = 113 bits (283), Expect = 2e-24
Identities = 221/962 (22%), Positives = 351/962 (36%), Gaps = 129/962 (13%)
Query: 1862 KRSRSRASPATHRRSRSRTPLISRR-----RSRSRTSPVSRRRSRSRTSVTRRRSRSRAS 1916
KR +++A A + L++ R R +P + R + +V R+ RA
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 1917 PVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP 1976
+ + P R +R+ T R+ + PP + R R+ P + S S
Sbjct: 64 GIGG----ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERA---PPAKNTSPGPVSS 116
Query: 1977 ITRRRSRSRTSPVTRRRSR-SRTSPVTRRRS-----RSRTSPVTRRRSRSRTP----PAI 2026
R +R P+ ++ R S V R ++ RS S RR + TP PA+
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 2027 RRRSRSRTPLL----PRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASG 2082
RRSR+ + P +R R P R+S S + + S T PA RRR ++G
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS-----SASEHSTTEPSPAARRRPSAG 231
Query: 2083 SSSDR--SRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSM-SPTPLDRCRSPGMLEPL 2139
R SRS + AT S +R+ P A + R + PS P L R P + P
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQVTPPR 289
Query: 2140 GSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARP--PP 2197
+ + L S + P P + P+N A A + L T P PP
Sbjct: 290 KDAAPALGPLSS---SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 2198 SMSAAGLAARMSQVPAPVPLM---SLRTAPAA---NLASRIPAASAAAMNLASARTPAIP 2251
S SA + PA P S+ T P +L + P ++ S + P P
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Query: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAP--SAVNLADPRTPTAPAVNLAGARTPAALAA- 2308
A++ + T + + ++P + +L P P + + + P +L A
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
Query: 2309 ----LSLTGSGTP--------PTAANYPSSSRTPQAPASANLVGPRSAHAT-APVNIAGS 2355
SL+ + +P P A +S +PQAP S+ ++ P ++ AP ++
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
Query: 2356 RTAAALAPASLTSARMAPALSGAN--LTSPRV-------PLSAYERVSGRTSPPLLDRAR 2406
+ P + P L A+ LT+P + P S T+PP +
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586
Query: 2407 SRTPP--SAPSQSRMTSERAPSP-----SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS 2459
TPP + P+ + + PSP ++ QAP LPP Q P P S
Sbjct: 587 IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS--- 643
Query: 2460 RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGV--PHSDVGEPPASTGA-- 2515
P+A + A+A A P+P V P S PP S A
Sbjct: 644 --------PLATPSPQAPNALAVHLLQAP----FSPPPSPPVQAPFSPPASPPVSPSATP 691
Query: 2516 --QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Q P +LAA P + S +S S S++ + ++ S +S P+ P
Sbjct: 692 PSQAPPSLAA-PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750
Query: 2574 VA-------------LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620
L+ PSP + + PP+ PA + S +S
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810
Query: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP-PGERRSRSPR 2679
+ S S+S S ++ + ++ P P A P +P++PP PG P
Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG------PD 864
Query: 2680 KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETP 2739
+ R + +L+ P P P P SS+ G + S + R
Sbjct: 865 TSVSGPRLTLALA--------PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
Query: 2740 SP 2741
P
Sbjct: 917 GP 918
Score = 88.6 bits (218), Expect = 8e-17
Identities = 203/897 (22%), Positives = 307/897 (34%), Gaps = 164/897 (18%)
Query: 337 DKDKDKKEKSATRPSPSPE-------RSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
D +DK + A +P+ R P PP P A R G+ + PL++
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE- 60
Query: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
R+ +P+S+ P PT+ + +S +P S PA G
Sbjct: 61 -------------RAGGIGGATIPESA------PRAGPTRSAGTSSRNPASRPPASGRGE 101
Query: 450 HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSR 509
+P +KN S G +P R G +R ++G S T +
Sbjct: 102 R-----APPAKNTSPGPVS-------SPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 510 SPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRS-PA 568
+P+ RSA G R +P P + +R ++ G R +R P
Sbjct: 150 APK----RSALSAGARRDTS----GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
Query: 569 TRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR 628
T G +S + A + +PA RR S +R PA R S S TP
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-----PASRSLSSSATPLS------ 250
Query: 629 SPVRRRSRSRSPARR--SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP 686
SPAR S R R PA + P +G R P TP
Sbjct: 251 ----------SPARSGPSARGTPRAPAHPSQ-----PKPKGLQALRPP--------QVTP 287
Query: 687 ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSS 746
R + P G S L TP G + + T + S
Sbjct: 288 PR----KDAAPALGPLSSSPLA--------TPSPSGTKARPVPPPDNAATPLPATLPPSP 335
Query: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKA 806
P L+ L+ SP QT P + SQ
Sbjct: 336 P-------------------------LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT 866
TPP ++ PP ++ P + HS +SP + PP +++S QA +
Sbjct: 371 SMTTPPMQA------PPSLQTIPPIQVPHSLTSPSLQ----APPSPLALSSLQATTSLGS 420
Query: 867 PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPR 926
P ++ + +P + S +SP R +STPP P ++ P P
Sbjct: 421 PTLQATH------SFLTMSPRQTQASLTSPSR-PASTPPDSPPLQAPLSLP----ASPPL 469
Query: 927 QRSHSGSSSPSPSRVTSRTTPRRS--RSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE-- 982
Q S S + SP S +T S S SP + + S ++P S +P + P
Sbjct: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529
Query: 983 -TPPRQSHSGSISPYPKVKAQTP---PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAG 1038
T P + S++P P A P P +PCP + L P + S A
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA- 588
Query: 1039 VKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGR 1098
TPP ++ ++S L+G SP + P P LQ+
Sbjct: 589 ----TPPPQAPPALASPPLQG--LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642
Query: 1099 SRSSSPVTELASRSPIRQDRGEFS--ASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQ 1156
S ++P + + + + FS SP +++ SP S S S++ P+ SL
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 1157 SRLETAESKEKMALPPQEDATASPPRQKDKFS--PFPVQDRPESSLVFKDTLRTPPR 1211
L+ S A PP + PP+ + P V P +S + PPR
Sbjct: 703 P-LQVPPSPP--ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
Score = 82.8 bits (203), Expect = 4e-15
Identities = 268/1183 (22%), Positives = 393/1183 (33%), Gaps = 233/1183 (19%)
Query: 628 RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRS--RSRT 685
R + + +R+PA R+ TP G R P R A GR R
Sbjct: 5 RDKAKAGAAARTPAARA--PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 686 PARRGRSRSRT-PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR---TSQRRS 741
G + + PR G +RS R+ + P GR + KN S +S R+
Sbjct: 63 GGIGGATIPESAPRAGPTRSAGT--SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
Query: 742 RSNSSPE---MKKSRISSR----RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP 794
+ P K RIS+ R ++ +P+ A S RR SG P P S
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA-GARRDTSG--PTPGTPSPAMA 177
Query: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS 854
RRSR+ ++ P R R + P K S S HS++ P P + P G
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS---SASEHSTTEPSPAARR-RPSAGGG 233
Query: 855 ITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS 914
+ P + S SS P +P+R S PR +P+ S
Sbjct: 234 LQRPASRSLS----------SSATP---LSSPARSGPSARGTPR---------APAHPSQ 271
Query: 915 PQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSS 974
P+PK + P Q TP R + + S L S SG
Sbjct: 272 PKPKGLQALRPPQ-----------------VTPPRKDAAPALGPLSSSPLATPSPSG--- 311
Query: 975 PDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLS 1034
TK +P PP + +P P A PP P L+ P S +Q+ P
Sbjct: 312 --TKARPVPPP----DNAATPLP---ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP-- 360
Query: 1035 LCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSS---PEVRQSHS-ESPSLQSKS 1090
+TPP ++ S T+P ++ S P ++ HS SPSLQ+
Sbjct: 361 ------PATPPSQA----------PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA-- 402
Query: 1091 QTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDS 1150
P + SS T SP Q F MSP Q++ S S P
Sbjct: 403 ---PPSPLALSSLQATTSLG-SPTLQATHSFLT-------MSPRQTQASLTSPSRPA--- 448
Query: 1151 NSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPP 1210
+ PP SPP Q +P + P L+T
Sbjct: 449 ------------------STPPD-----SPPLQ----APLSLPASPP--------LQTSL 473
Query: 1211 RERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES 1270
SSP T AL + + S P + S + L+ S+
Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLA-----------SHSPQAPLSSLIMPPLETQSSL---- 518
Query: 1271 SPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHF------SPEHKELSNSPLRE 1324
+P + P SLT ++ SL + + ++ PH +P + SPL
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578
Query: 1325 NSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPS-----LDMKEQSTRSS 1379
+P P + +S + L P L+ L T P L + S
Sbjct: 579 PPPETPSSIATPPP---QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
Query: 1380 GHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRS 1439
+S LSP A + +++ +L A P + SP
Sbjct: 636 PPASPPLSPLATPSP--QAPNALAVHLLQAPFSPPPSPPVQAPFSPP------------- 680
Query: 1440 RSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRS 1499
+SP + + PS+ S ++P ++ P P+ ++P P+A P P +
Sbjct: 681 ---ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737
Query: 1500 PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERS-E 1558
P SP +P S + +A PL +S L + P A P ++
Sbjct: 738 PPSPP-----ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS--LPMSPLAKPPPQAPP 790
Query: 1559 SDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGS 1618
+ ++P +A P ++ SP + +SP + +P V AAP Q
Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSP--SASLPMSPLATPPPQAPPV----LAAPLLQVPP 844
Query: 1619 DSSPEPKAPAPRALPRRSRSGSSSKGR-------GPSPEGSSSTESSPEHPPKSRTARRG 1671
P APR P S S R GP P S S S+ P + G
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA-----G 899
Query: 1672 SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPP---RHRRSP 1728
SS + TP R S PE A + A+ P SR P R +P
Sbjct: 900 HSSS-----ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 954
Query: 1729 SVSSPEPAEKSRSSR----RRRSASSPRTKTTSRRGRSPSPKP 1767
P P S P + T + P P P
Sbjct: 955 GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997
Score = 62.0 bits (149), Expect = 8e-09
Identities = 98/374 (26%), Positives = 131/374 (35%), Gaps = 61/374 (16%)
Query: 105 PGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSS--FDPQRRA-REAK 161
PG P PA A +K RA GI + + S+ P R A ++
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG-GIGGATIPESAPRAGPTRSAGTSSR 88
Query: 162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE 221
PA PP R+P K GR S ++ P +K + S
Sbjct: 89 NPASRPPA------SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI----SA 138
Query: 222 SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS-------ASSS-- 272
E+ R + PK S +R S T P A RS +A + A S+
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198
Query: 273 --DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSP------ 324
T R ++A H+T PSPA+ RR P + S ++P
Sbjct: 199 RPPTEGPRKSVSSASEHSTT----EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 325 --ETATKQPSSPYEDKDKDKKEKSATRPSP-SPERSSTGPEPPAPTPLLAERHGGSPQPL 381
+A P +P K A RP +P R P A PL S PL
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP---ALGPL-------SSSPL 304
Query: 382 ATTPLS---QEPVNPPSEASPTRDRSPPKSP---EKLPQSSSSESSPPSPQPTKVSRHAS 435
AT S PV PP A+ + P SP LP + S S+PPS Q
Sbjct: 305 ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ-------TL 357
Query: 436 SSPESPKPAPAPGS 449
SP + P+ AP S
Sbjct: 358 PSPPATPPSQAPPS 371
Score = 60.5 bits (145), Expect = 2e-08
Identities = 73/337 (21%), Positives = 119/337 (35%), Gaps = 51/337 (15%)
Query: 158 REAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRR--ERKKSSKK 215
R P P PP + +R ++ + K ++ G S+PR R +
Sbjct: 28 RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87
Query: 216 KKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTT-PAPKSRRAHRSTSADSASSSDT 274
+ S + R R+P K+ R+ TT P P ++ R ++ ++ +
Sbjct: 88 RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 275 SRSRSRSA---AAKTHTTALAGRSPSPASGRRGEG---DAPFSEPGTTSTQRP------- 321
+ + RSA A+ T+ +PSPA RR + P ++ RP
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 207
Query: 322 ---SSPETATKQPSSPYE---------DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPL 369
S+ E +T +PS + + S+ P SP RS P A
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----PSARGTP 263
Query: 370 LAERHGGSPQPL-------------------ATTPLSQEPVNPPSEASPTRDRSPPKSPE 410
A H P+P A PLS P+ PS + PP
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNA 323
Query: 411 KLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAP 447
P ++ SPP P ++ + S+P S + P+P
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
Score = 55.5 bits (132), Expect = 7e-07
Identities = 51/164 (31%), Positives = 63/164 (38%), Gaps = 16/164 (9%)
Query: 308 APFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP---SPSPERS-----ST 359
APFS P + Q P SP + P SP A P PSP S S
Sbjct: 663 APFSPPPSPPVQAPFSPPASP--PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720
Query: 360 GPEPPAPTPLLAERHGGSPQPLATTPLSQE----PVNPPSEASPTRDRSPPKSPEKLPQS 415
P P AP PL A P P A+ P+S P PP A+P + PP P LP S
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL-QVPPSPPASLPMS 779
Query: 416 SSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTS 459
++ P +P P + + P P P +S P S
Sbjct: 780 PLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
Score = 50.1 bits (118), Expect = 3e-05
Identities = 58/276 (21%), Positives = 99/276 (35%), Gaps = 37/276 (13%)
Query: 2477 SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536
+GA A T ++ G+L+ PG P PA+ + +P ER
Sbjct: 10 AGAAARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPP 2596
++ S+ + + S+ +SS + +S S + A P P +P A RP
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
P K R S+ + + ++ + S+ S+ + +S + + S + + S A
Sbjct: 128 -PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 2657 QALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSE 2716
LP+PA +P P P PR SS+SE
Sbjct: 187 VGLPRPAPSARPRP--------------------------------PTEGPRKSVSSASE 214
Query: 2717 RGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
+ R PS + P+ R + SS +P
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSL--SSSATP 248
Score = 50.1 bits (118), Expect = 3e-05
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 31/186 (16%)
Query: 288 TTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQ-PSSPYEDKDKDKKEKS 346
TT PS A AP + P + P P Q P SP +
Sbjct: 531 TTPPLENLPSLAPPPLQTASAPLTTP---HLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Query: 347 ATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP--VNPPSEASPTRDRS 404
AT P +P ++ P P+P L+ PLAT P P PP +A P+ S
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLS--------PLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 405 PPKSPEKLPQSSSSESSPPSPQ-PTKVSRHASSSPESPKPAP------APGSHREISSSP 457
PP SP + PSPQ P ++ H +P SP P+P +P + +S S
Sbjct: 640 PPLSP----------LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 689
Query: 458 TSKNRS 463
T +++
Sbjct: 690 TPPSQA 695
Score = 48.5 bits (114), Expect = 9e-05
Identities = 44/158 (27%), Positives = 59/158 (37%), Gaps = 23/158 (14%)
Query: 309 PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSS-----TGPEP 363
P P + +T P +P S P + AT P +P + P P
Sbjct: 580 PPETPSSIATPPPQAPPALA---SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP 636
Query: 364 PAPTPL--LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESS 421
PA PL LA +P LA L Q P +PP SPP SP P ++ +
Sbjct: 637 PASPPLSPLATPSPQAPNALAVH-LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 695
Query: 422 PPS------------PQPTKVSRHASSSPESPKPAPAP 447
PPS P +S A+ P++P P AP
Sbjct: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733
Score = 47.8 bits (112), Expect = 2e-04
Identities = 94/411 (22%), Positives = 139/411 (33%), Gaps = 84/411 (20%)
Query: 101 KDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREA 160
K+ +PG +PG+ T L + + + A G + S+ R R+
Sbjct: 107 KNTSPG-PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR-RDT 164
Query: 161 KQPAPEPPKP------------YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESS-SPRR 207
P P P P L R + S+R P + +K S + SP
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224
Query: 208 ERKKSSKKKKHR--SESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTS 265
R+ S+ R S S S S +S ++ R + + P PK +A R
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 266 ADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPS--- 322
R + A ++ LA SPS R P P +T P+
Sbjct: 285 VTPP------RKDAAPALGPLSSSPLATPSPSGTKAR------PVPPPDNAATPLPATLP 332
Query: 323 -SPETATKQPSSPYEDKDKDKKEK----SATRPSPSPERSSTGP--EPPA---------P 366
SP AT P +P + AT PS +P +T P PP+ P
Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 367 TPLLAERHGGSPQPLATTPL------------------------SQEPVNPPSEASPTRD 402
L + P PLA + L +Q + PS + T
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 403 RSPP-KSPEKLP-----QSSSSESSPPSPQPTKV------SRHASSSPESP 441
SPP ++P LP Q+S S + P P + S AS SP++P
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503
Score = 40.0 bits (92), Expect = 0.032
Identities = 72/287 (25%), Positives = 97/287 (33%), Gaps = 47/287 (16%)
Query: 295 SPSPASGRRGEGDAPFSEPGTTSTQRPSS-------------PETATKQPSSPYEDKDKD 341
SP P+ + P S P + S PS P P SP
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 342 KKEKSATRP---SPSPERS---STGPEPPAPTP--LLAERHGGSPQPLATTPLS----QE 389
A P PSP S S PP P L A P P A+ P+S
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 390 PVNPPSEASPTRDR--SPPKS-PEKLPQSSSSE------SSPPSPQPTKVSRHASSSPES 440
P PP+ A+P SPP S P + P S S+ ++PP P ++ P S
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845
Query: 441 PKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTP 500
P +P + R + + S R + + P SRSP++ G P
Sbjct: 846 PPASPTLQAPRRPPTPGPDTSVSGPRL----TLALAPGPPPPPSRSPSSTLSG------P 895
Query: 501 TKRGHSRSRS---PQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSR 544
GHS S + + R S G + SP + WSR
Sbjct: 896 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 942
Score = 34.7 bits (78), Expect = 1.3
Identities = 48/201 (23%), Positives = 63/201 (31%), Gaps = 17/201 (8%)
Query: 248 SRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPS--PASGRRGE 305
S S TP P++ + S S S SA L P P S
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 306 GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA 365
+P ++P P +P P ++ PS S S PP
Sbjct: 777 PMSPLAKPP------PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Query: 366 PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP-------PKSPEKLPQSSSS 418
P+LA P +P Q P PP+ T P P P P S S
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP--PPSRSP 888
Query: 419 ESSPPSPQPTKVSRHASSSPE 439
S+ P S A+S+PE
Sbjct: 889 SSTLSGPDLAGHSSSATSTPE 909
Score = 34.3 bits (77), Expect = 1.7
Identities = 35/140 (25%), Positives = 52/140 (37%), Gaps = 12/140 (8%)
Query: 318 TQRPSSPETATKQPSSPYEDK-DKDKKEKSATRPSPSPERSSTGPE-PPAPTPL------ 369
T P + + PS P D + + P+ P ++S P P +PL
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 370 -LAERHGGSPQ-PLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP 427
L+ SPQ PL++ L P+ S +P ++PP S P + +PP Q
Sbjct: 491 ALSSLASHSPQAPLSS--LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 428 TKVSRHASSSPESPKPAPAP 447
P PAP P
Sbjct: 549 ASAPLTTPHLETPPCPAPCP 568
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 141 bits (356), Expect = 8e-33
Identities = 419/1936 (21%), Positives = 690/1936 (35%), Gaps = 276/1936 (14%)
Query: 890 SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRS-HSGSSSPSPSRVTSR---- 944
S S S +K++T P SP ++ S + HS S+SP S S+
Sbjct: 581 SPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHT 640
Query: 945 ----TTP--RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPK 998
TT + +RSVSP ++ ++ P S + S +++ P+ P S + + +P P
Sbjct: 641 QAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPT 700
Query: 999 VKAQTPPGPSLSGSKSPCPQEKS-----------------KDSLVQSCPGSLSLCAGVKS 1041
T P+ + +P + + +S+V + G +
Sbjct: 701 GDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASA 760
Query: 1042 STPPGESY-----FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKG 1096
ST P + S + GQ+QTS +S + + +PS S T+P G
Sbjct: 761 STSPDTAAAMTHTHQAESTEASGQTQTS---EPASSGSRTTSAGTATPSSSGASGTTPSG 817
Query: 1097 GRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMS----PEQSRFQSD---SSSYPTVD 1149
S+S T S +P R S + +L + S P + S + +PT+
Sbjct: 818 SEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLS 877
Query: 1150 SNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRT- 1208
S G+ +++ + + PQE A S Q + D + DT T
Sbjct: 878 EASTAGRPTGQSSPTSPSAS--PQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTV 935
Query: 1209 ---PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMST 1265
PP S +SP+T+ + S + + + P S + +
Sbjct: 936 PPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHV 995
Query: 1266 SNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLREN 1325
++ S P + +T S S + V +S G +PL
Sbjct: 996 TDASSVSTGHATP-LPVTSPSSVSTGHTTPLPVTDTSSESTG----------HVTPLPVT 1044
Query: 1326 SFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPS--LDMKEQSTRSSGHSS 1383
SF S +S PL + S+ L L+ T + L + + S+ S+GH++
Sbjct: 1045 SFSSA-STGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHAT 1103
Query: 1384 SELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGS 1443
S D + +S+ + PV D +S++S LP T + +G
Sbjct: 1104 SLPVTDT---SSVSTGHTTPLPVTD-----------TSSASTGHATSLPVTDTSSVSTGH 1149
Query: 1444 SPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP--- 1500
+ L + S S+ +P T S D++P P P + +P
Sbjct: 1150 TTPLHVTDAS------SASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLV 1203
Query: 1501 -SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSES 1559
+ + TP S S D T + + +G + L V ++S +
Sbjct: 1204 TDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQAT 1263
Query: 1560 -----DSSPDSKAKTRTPLRQRSRSGSSP-EVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
D+S S T TPL S S +S V SP + +G + + P +
Sbjct: 1264 SLLVTDTSSVSTGDT-TPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPL---PVTSLS 1319
Query: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS----PEHPPKSRTAR 1669
+ S D+ P LP S S +S+ P P +S+ S+ P H + +A
Sbjct: 1320 SASTGDTMP---------LPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSAS 1370
Query: 1670 RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS 1729
G +++P P T SS S+ + T S SAS+ T S
Sbjct: 1371 TG-QATPLPVTSL-------SSVSTGDTTPLPVTS--PSSASTGHATPLLVTDTSSASTG 1420
Query: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
++P P + S + S P T ++ +P P S S + T
Sbjct: 1421 HATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSS 1480
Query: 1790 RSGSSQ------STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843
S STS + VT +G+ + P SS ++ G +
Sbjct: 1481 VSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSAST-----GDTM 1535
Query: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
P + S S P + + + H T S + PV+ S S+
Sbjct: 1536 PLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASK 1595
Query: 1904 TSVTRRRSRSRAS---------PVSRRRSRSR---TP-PVTRRRSRSR---------TPT 1941
T S +S PV+ S S TP PVT S S +P+
Sbjct: 1596 GDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPS 1655
Query: 1942 TRRRSRSRTPPVTRRRSRSR---TP-PVTRRRSRSRTS----PITRRRSRSRTS----PV 1989
+ + PVT S S TP PVT S + P+T S S PV
Sbjct: 1656 SASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPV 1715
Query: 1990 TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR----SR 2045
T S S T T S +S T S A + TPL S
Sbjct: 1716 TSLSSVS-TGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHA 1774
Query: 2046 SPLAIRRRSRSRTPRTAR------GKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
+PL + S + T T R S ++ P +S S+ D + A+
Sbjct: 1775 TPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSAS 1834
Query: 2100 SGSRTP-PVALNSSRMS--CFSRPSMSPTPLDRCRSPGMLEPLGSS-----RTPMSVLQQ 2151
+G T PV + SS S S P + + + +L SS TP+ V
Sbjct: 1835 TGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDT 1894
Query: 2152 AGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQV 2211
S D + D +SV HA S +L++ S G P P S + ++ +
Sbjct: 1895 NSASTGDTTPLHVTD--ASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHT-- 1950
Query: 2212 PAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSR------TPAAA 2265
P+P+ + P + A+ +P A++++ A + A +++ T ++
Sbjct: 1951 -TPLPVTDASSVPTGH-ATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSS 2008
Query: 2266 AAMNLASPRTAVAPSAVNLAD----PRTPTAPAVNLAGARTPAALAALSLTGSG-TPPTA 2320
+ A+P + S+ + D P T T+ A G TP + +LS +G T P
Sbjct: 2009 VSTGQATPLPVTSLSSASTGDTTPLPVTDTSSAST--GQDTPLPVTSLSSVSTGDTTPLP 2066
Query: 2321 ANYPSSSRTPQAP--------------ASANLVGPRSA----HATA-PVNIAGSRTAAAL 2361
PSS+ T A A++ LV S+ HATA V A S +
Sbjct: 2067 VTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDT 2126
Query: 2362 APASLTSARMAPALSGANLTSPRVPLSAYERVSG--RTSPPLLDRARSRTP-----PSAP 2414
P +TS P+ + T+P +P++ VS TS P+ D + + T P
Sbjct: 2127 TPLPVTS----PSSASTGDTTP-LPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTD 2181
Query: 2415 SQSRMTSERAPSP-----SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV 2469
+ S T P P S+ GQA + P+ +P +D S Q TP+
Sbjct: 2182 TSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPL 2241
Query: 2470 AGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE 2529
+ S+ TT D + + + A +P + + STG P +
Sbjct: 2242 PVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSS--VSTGDTTPLPV-------- 2291
Query: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589
+S SS+S+ ++ + +SS+S+G + TP P +
Sbjct: 2292 ---TSPSSASTGHATPLHVTDASSASTGHA-----------------------TPLPVTS 2325
Query: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
+ + TP SS+S+ ++ + +SS S+ ++ +SSSS+ SS ++P
Sbjct: 2326 LSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSA-SSGHTTP 2384
Query: 2650 SPAKPGPQALPKPASP 2665
P A +P
Sbjct: 2385 LPVTDASSASTGDTTP 2400
Score = 129 bits (324), Expect = 4e-29
Identities = 472/2108 (22%), Positives = 728/2108 (34%), Gaps = 333/2108 (15%)
Query: 829 TPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR 888
+PS S ++P P + + + + P + S + + + + +
Sbjct: 2133 SPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATP 2192
Query: 889 HSCSGSSPPRVKSSTP-PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP-----SRVT 942
+ +S +TP P SPS S+S + +++ + +G ++P P S T
Sbjct: 2193 LPVTDTSSASTGQATPLPVTSPS-SASTGHAIPLLVTDTSSASTGQATPLPVTSLSSAST 2251
Query: 943 SRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ 1002
TTP S S + LP S S S+ DT P T P + +G +P A
Sbjct: 2252 GDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDAS 2311
Query: 1003 -------TP-PGPSLS----GSKSPCP-QEKSKDSLVQSCPGSLSLCAGVKSS-TPPGES 1048
TP P SLS G +P P S S + P ++ + V + T P
Sbjct: 2312 SASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTP--- 2368
Query: 1049 YFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL 1108
V+S T+P +D SS S ++ L +S G + + PVT L
Sbjct: 2369 -LPVTSSSSASSGHTTPLPVTDASSA----STGDTTPLPVTDTSSASTGHA-THLPVTGL 2422
Query: 1109 ASRSPIRQDRGEFSASPMLKSG------MSPEQSRFQSDSSSYPTVDSNSL-------LG 1155
+S S R + +G ++ S D++ P D++S+ L
Sbjct: 2423 SSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLL 2482
Query: 1156 QSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSG 1215
+ + + + LP ++AS +P PV D P +S DT P S
Sbjct: 2483 VTDASSVSTGDTTRLPVTSPSSASTGHT----TPLPVTDTPSAST--GDTTPLPVTNASS 2536
Query: 1216 AGSSPETK-EQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEV 1274
+ T S S+ + V + S G + ST + P
Sbjct: 2537 LSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVT 2596
Query: 1275 EERPAVS-----LTLDQSQSQASLEAVEVP-SMASSWGGPHFSPEHKELSNSPLRENSFG 1328
+ A + L + + S ++ + +P + SS H +P ++N+
Sbjct: 2597 DTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATP--LPVTNTSSVSTGHA 2654
Query: 1329 SPLEFRNSGPLGT------------EMNTGFSSEVK-EDLNGPFLNQLETDPSLDMKEQS 1375
+PL + T ++TG ++ + D + F SL + S
Sbjct: 2655 TPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHAT---SLPVTIPS 2711
Query: 1376 TRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVP-----RTPSRERSSSASSPEMKDG 1430
+ SSGH++ DA + +S+ + S PV DA TP +S+ S
Sbjct: 2712 SASSGHTTPLPVTDA---SSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP 2768
Query: 1431 LPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP 1490
LP T S SS D + P + S S+ +P T S D++P P
Sbjct: 2769 LPLT------SLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLP-VTD 2821
Query: 1491 QTPRPRSRSPSSPELNNKCL-----TPQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL 1545
+ + S P + TP + S +S T+ + G + L
Sbjct: 2822 TSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSL 2881
Query: 1546 DVKPSAS-------------PQERSESDSSP-----DSKAKT--RTPLRQRSRSGSS--- 1582
V ++S P S ++P S A T PL S S +S
Sbjct: 2882 PVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGH 2941
Query: 1583 ----PEVDSKS----RLSPRRSRSGSSPEVKDK---PRAAPRAQSGSDSSPEPKAPAPRA 1631
P D+ S +P S SS D P +P + S ++P P A
Sbjct: 2942 ATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSA 3001
Query: 1632 -------LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRT 1684
LP S S +S+ P P +S+ S+ + P T+ + +
Sbjct: 3002 STGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTS 3061
Query: 1685 PPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR 1744
P + ++P L A SAS+ T S ++P P S+
Sbjct: 3062 PSSASTGHATPLLVTDAS------SASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAST 3115
Query: 1745 RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804
+ S P T T+S + P S + T + D S SS +
Sbjct: 3116 GHATSLPVTDTSSASTGDTTSLP---VTDTSSAYTGDTTSLPVTDTSSSSTGDT------ 3166
Query: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRS 1864
+ VT +G H+ ++S S+ T P+S S T+P P +
Sbjct: 3167 -TPLLVTETSSVSTG-HATPLLVTDASSASTGHATPLHVTSPSSA--STGDTTPVPVTDT 3222
Query: 1865 RSRAS------PATHRRSRSR--------TPLISRRRSRSRTSPVSRRRSRSRTS----- 1905
S ++ P T S S T + S ++ PV+ S S
Sbjct: 3223 SSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLP 3282
Query: 1906 VTRRRSRSRAS----PVSRRRSRSR---TP-PVTRRRSRSR--------TPTTRRRSRSR 1949
VT S S PV+ S S TP PVT S S T T+ +
Sbjct: 3283 VTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDT 3342
Query: 1950 TP-PVTRRRSRSR--------TPPVTRRRSRSRTSPITRRRSRSRTS----PVTRRRSRS 1996
TP PVT S S T P + + T P+T S S PVT S S
Sbjct: 3343 TPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVS 3402
Query: 1997 RTS----PVTRRRSRSRTS----PVTRRRSRSR---TPPAIRRRSR----SRTPLLPRKR 2041
PVT S S PVT S S TP + S TPLL
Sbjct: 3403 TGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDA 3462
Query: 2042 SR----SRSPLAIRRRSRSRTPRTAR------GKRSLTRSPPAIRRRSASGSSSDRSRSA 2091
S +PL + S + T T R S ++ P +S S+ D +
Sbjct: 3463 SSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLL 3522
Query: 2092 TPPATRNHSGSRTP-PVALNSS-------RMSCFSRPSMS-------PTPLDRCRSPGML 2136
A+ +G TP PV SS R+ S S P + S G
Sbjct: 3523 VTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHT 3582
Query: 2137 EPLGSSRT---------PMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTA 2187
PL + T P+ V + S G +P +S HA + ++
Sbjct: 3583 TPLPVTSTSSVSTGHVTPLHVTSPSSAST--GHVTPLPVTSTSSASTGHATPLLVTDASS 3640
Query: 2188 ISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASART 2247
+S G A P P A+ A+ P PV S +A+ P + ++++ T
Sbjct: 3641 VSTGHATPLPVTDASS-ASTGDTTPLPVTDTS-----SASTGQATPLPVTSLSSVSTGDT 3694
Query: 2248 PAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLAD--PRTPTAPAVNLAGARTPAA 2305
+P T A++A+ A+P PS+V+ D P T+P+ G TP
Sbjct: 3695 TPLPV--------TDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLP 3746
Query: 2306 LAALSL--TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATA--PVNIAGSRTAAAL 2361
+ LS TG TP + S+S P S T PV S +
Sbjct: 3747 VTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHA 3806
Query: 2362 APASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAP-----SQ 2416
P +TS A S + T V ++ TS P+ R+ + T + P +
Sbjct: 3807 TPLPVTSTSSA---STGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTS 3863
Query: 2417 SRMTSERAPSP-----SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP--V 2469
S T P P S G A + P+ P + S TTP V
Sbjct: 3864 SVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPV 3923
Query: 2470 AGSQSLSSGAVAT--TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQ-- 2525
+ SLS+G TS + G S +P +D ASTG P L +L
Sbjct: 3924 TNASSLSTGHATPLHVTSPSSASRGDTST----LPVTDASS--ASTGHATPLPLTSLSSV 3977
Query: 2526 --------PAKERRSSSSSSSSSSSSSSSSSSSS-----------SSSSSG--------- 2557
P + S+S+ ++ +S SS S+ SS+SSG
Sbjct: 3978 STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTD 4037
Query: 2558 -SSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
SS S G+ LPV + TP P TP SS+S+ ++
Sbjct: 4038 ASSVSTGHGTPLPVT-STSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATP 4096
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
+S SS S+ ++ + SS++S+S+ SS SP + P +P G RR+
Sbjct: 4097 LPVTSLSSVSTGHATPLAVSSATSASTVSSDSPLKME-----TPGMTTPSLKTDGGRRTA 4151
Query: 2677 SPRKPIDS 2684
+ P S
Sbjct: 4152 TSPPPTTS 4159
Score = 129 bits (323), Expect = 5e-29
Identities = 553/2678 (20%), Positives = 898/2678 (33%), Gaps = 319/2678 (11%)
Query: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225
EP +P + S++ T + + ++ G E+ + K S S S
Sbjct: 541 EPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSP 600
Query: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPK---SRRAHRSTSADSASSSDTSRSRSRSA 282
+ + S + S ST+P S+R H + + + S T+RS S
Sbjct: 601 MLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGH-TQAPQTTQESQTTRSVSPMT 659
Query: 283 AAKTHTT-----ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
KT TT +G SPS + DAP TT P+ T+ P++ +
Sbjct: 660 DTKTVTTPGSSFTASGHSPSEIVPQ----DAPTISAATTFAPAPTGDGHTTQAPTTALQA 715
Query: 338 KDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEA 397
+ PS S TG A + + G P+ T+ + +P + A
Sbjct: 716 APSS--HDATLGPSGGTSLSKTGALTLANSVVSTP---GGPEGQWTS--ASASTSPDTAA 768
Query: 398 SPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSP 457
+ T E S +++S P+ ++ + +++P S + S E S+
Sbjct: 769 AMTHTHQA----ESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTS 824
Query: 458 TSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT--AKRGRSRSRTPTKRGHSRSRSPQWRR 515
R RD + + + + S S G + S P + P
Sbjct: 825 GETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVP------GTFHPTLSE 878
Query: 516 SRSAQRWGRSRSPQRRGRSRSPQR-PGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSR 574
+ +A R SP S SPQ SR TQR SR S + S A++
Sbjct: 879 ASTAGRPTGQSSP--TSPSASPQETAAISRMAQTQRTRTSRG-----SDTISLASQATDT 931
Query: 575 SRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRR 634
T TP S T + + + +P+ G ++ T A + T PV
Sbjct: 932 FSTV-------PPTPPSITSTGLTSPQTETHTLSPS--GSGKTFTTALISNATPLPVTYA 982
Query: 635 SRSRSPARRSGRSRSRTPARRGRS-----RSRTPARRGRSRSRTPARRSGRSRSR----- 684
S + + + G + S + G + S S
Sbjct: 983 SSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLP 1042
Query: 685 -TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRS 743
T + TP S + T +G ++ +S +
Sbjct: 1043 VTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHA 1102
Query: 744 NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ 803
S P S +S+ + L + + S SL + T P SS
Sbjct: 1103 TSLPVTDTSSVSTGHTTPLPVTDTSSAS-TGHATSLPVTDTSSVSTGHTTPLHVTDASSA 1161
Query: 804 PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQ 863
++ P S SS S S S S+ P + + T S ++ A
Sbjct: 1162 STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDT----SSASTGHATPL 1217
Query: 864 SVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAII 923
VT S + L PS S ++P V ++ S+S ++
Sbjct: 1218 PVTD--ASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTS--------SASTGQATSLLV 1267
Query: 924 SPRQRSHSGSSSPSP-----SRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTK 978
+ +G ++P P S T TP S S S + LP S S +S+ DT
Sbjct: 1268 TDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTM 1327
Query: 979 VKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPC-PQEKSKDSLVQSCPGSLSLCA 1037
P T P + +G +P P A + +G +P + S S Q+ P ++ +
Sbjct: 1328 PLPVTSPSSASTGDTTPLPVTDASSVS----TGHTTPLHVTDASSASTGQATPLPVTSLS 1383
Query: 1038 GVKS--------STPPGESYFGVSSLQLKGQSQTSPDHRSD---TSSPEVRQSHSES--- 1083
V + ++P S + L + S S H + T + V H+ S
Sbjct: 1384 SVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPV 1443
Query: 1084 --PSLQSKSQTSP---KGGRSRSSSPVTELASRSPIRQDRGEFSASPM--LKSGMSPEQS 1136
PS S T+P S S+ T L G+ + P+ S + +
Sbjct: 1444 TIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVT 1503
Query: 1137 RFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRP 1196
S S + + L + L +A + + M LP ++AS +P PV D
Sbjct: 1504 PLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAS----TGDTTPLPVTDAS 1559
Query: 1197 ESSLVFKDTLR-TPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSH 1255
S L T P S ++P S+ S D + V S G
Sbjct: 1560 SVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSS--ASKGDTTPLPVTSPSSASTGHTTPL 1617
Query: 1256 LSSELKEMSTSNFESSP-----EVEERPAVSLTLDQSQSQASLEAVEVP-SMASSWGGPH 1309
++ ST + P + A L + S ++ A +P + SS H
Sbjct: 1618 PVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGH 1677
Query: 1310 FSPEHKELSNSPLRENSFGSPLEFRNSGPLG--TEMNTGFSSEVKEDLNGPFLNQLETDP 1367
+P +S +++ P+ +S G T + S V +T P
Sbjct: 1678 ATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTG---------DTTP 1728
Query: 1368 SLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLD-----AVPRTPSRERSSSA 1422
L + S+ S+GH+S L DA + S+ Q+ PV D TP S+
Sbjct: 1729 -LPVTSPSSASTGHASPLLVTDA---SSASTGQATPLPVTDTSSVSTAHATPLPVTGLSS 1784
Query: 1423 SSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDS 1482
+S + LP T + +G + L S PS S ++P +P T + S D+
Sbjct: 1785 ASTDDTTRLPVTDVSSASTGQAIPLPVTS--PSSASTGDTTP----LPVTDASSASTGDT 1838
Query: 1483 SPEPKALPQT---------PRPRSRSPSSPELNNKCLTPQRERSGSESSV-------DQK 1526
+ P +P + P + S S+ + +T S +++
Sbjct: 1839 TSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSAS 1898
Query: 1527 TVARTPLGQRSRSG-SSQELDVKPSASPQERSESDSSP-----DSKAKTRTPLRQRSRSG 1580
T TPL S S+ P S S D++P S A +
Sbjct: 1899 TGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDA 1958
Query: 1581 SSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA-------LP 1633
SS + L + S S+ P + S ++P P LP
Sbjct: 1959 SSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLP 2018
Query: 1634 RRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS 1693
S S +S+ P P +S+ S+ + P T+ + +P + +
Sbjct: 2019 VTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA 2078
Query: 1694 SPELTRKAR----------LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR 1743
+P L A L + S S+ T S ++P P S+
Sbjct: 2079 TPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSAS 2138
Query: 1744 RRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQR 1803
+ P T T+S + P S S T SS ST
Sbjct: 2139 TGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVT-----DTSSASTGH---- 2189
Query: 1804 SRSRSRVTRRRRGGSGYHSRSPARQESSRT-----------SSRRRRGRSRTPPTSRKRS 1852
+ VT +G + P SS + +S G++ P + S
Sbjct: 2190 -ATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSS 2248
Query: 1853 RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSR 1912
S P + + + H S T L S + PV+ S S T +
Sbjct: 2249 ASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSAS----TGHATP 2304
Query: 1913 SRASPVSRRRSRSRTP-PVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRS---RTPPVTRR 1968
+ S + TP PVT S S TT PVT S S TP
Sbjct: 2305 LHVTDASSASTGHATPLPVTSLSSASTGDTT-------PLPVTSPSSASTGHATPLHVTD 2357
Query: 1969 RSRSRTS-----PITRRRSRS--RTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR 2021
S T P+T S S T+P+ + S ++ T + TS + +
Sbjct: 2358 ASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHL 2417
Query: 2022 TPPAIRRRSRSRTPLLPRKRSRSRS-----PLAIRRRSRSRT------PRTARGKRSLTR 2070
+ S T LP S S PL + S + T P T S
Sbjct: 2418 PVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGH 2477
Query: 2071 SPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTP-PVALNSSRMSCFSRPSMSPTPLDR 2129
+ P + ++S S+ D +R + +G TP PV S S +P P+
Sbjct: 2478 TTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSA----STGDTTPLPVTN 2533
Query: 2130 CRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAIS 2189
S S+R S+ + S G +P ++ HA + ++ S
Sbjct: 2534 ASSL-------STRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSAS 2586
Query: 2190 LGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPA 2249
G P P + + P+P+ +A + + +P ++ + A
Sbjct: 2587 TGDTTPLPVTDTYSASTGQA---TPLPVTDTSSASTGD-TTPLPVTDTSSASTGH----A 2638
Query: 2250 IPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAAL 2309
P V S + A +++ SP +A L P T + P A+
Sbjct: 2639 TPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPL--PVTDASSVSTGHATSLPVTDASS 2696
Query: 2310 SLTGSGT--PPTAANYPSSSRTPQAPASANLVGPRSAHATA-PVNIAGSRTAAALAPASL 2366
TG T P T + SS T P + + + HAT+ PV A S + P +
Sbjct: 2697 VFTGHATSLPVTIPSSASSGHTTPLPVT-DASSVSTGHATSLPVTDASSVSTGHATPLPV 2755
Query: 2367 TSARMAPALSGANLTSPRVPLSAYERVS-GRTSP-PLLDRARSRTPPSAP-----SQSRM 2419
T A ++S + T +PL++ VS G T+P P+ D + + T + P S
Sbjct: 2756 TD---ASSVSTGHATP--LPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVS 2810
Query: 2420 TSERAPSP-----SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTT--PVAGS 2472
T + P P S+ G A S + + P +D S T PV +
Sbjct: 2811 TGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDT 2870
Query: 2473 QSLSSG-----AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPA 2527
S S G V T+S + H L V +P ASTG P P
Sbjct: 2871 SSASIGHATSLPVTDTSSISTGHATPLHVTSPS---------SASTGHATP------LPV 2915
Query: 2528 KERRSSSSSSSSS---SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPS--P 2582
+ S+S+ ++ +S SS+S+ ++ +SS S G + P+ P +L V +
Sbjct: 2916 TDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPL-PVTSLSSVSTGDT 2974
Query: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS----------SSSSS 2632
TP P + TP SS+S+ +++ +S+SS+S+ +SS+S
Sbjct: 2975 TPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSAS 3034
Query: 2633 SSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
+ ++ +S SS S P P P AS P
Sbjct: 3035 TGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP 3072
Score = 117 bits (294), Expect = 1e-25
Identities = 362/1753 (20%), Positives = 620/1753 (35%), Gaps = 226/1753 (12%)
Query: 1034 SLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKS-QT 1092
+L G K++ P + G ++ L+GQS + S+ Q+H Q+KS +T
Sbjct: 33 TLITGSKTAAPVTST--GSTTATLEGQSTAASSRTSNQDISASSQNH------QTKSTET 84
Query: 1093 SPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGM--SPEQSRFQSDSSSYPTVDS 1150
+ K + +T SP + E + + + S + + + T +
Sbjct: 85 TSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLMMTSKTITMTTST 144
Query: 1151 NSLLGQSR-LETAESKEKMALPPQEDATASPPRQKDKFS-PFPVQDRPESSLVFKDTLRT 1208
+S LG + TA ++ + TA Q S +QD SS
Sbjct: 145 DSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQ 204
Query: 1209 PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268
RE +S T S S + V + P+G+ + S L ++ ++
Sbjct: 205 TTRESQ---TSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETAT---SSLCSVTNTSM 258
Query: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG 1328
+S ++ + TL +S+ +S F PE +
Sbjct: 259 MTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQ------------- 305
Query: 1329 SPLEFRNSGPLGTEMNTGFSSEVK-EDLNGPFLNQLETDPSLDMKEQST--------RSS 1379
SP F + T+ T FS + + + ++Q+ T +L ST S
Sbjct: 306 SPATFSRTS---TQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPS 362
Query: 1380 GHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRS 1439
G S E P S+ S + V V R P+ S+ ++ E + T S +
Sbjct: 363 GTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAIT 422
Query: 1440 RSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRS 1499
S+ D T +LS SS K S + + + T RP RS
Sbjct: 423 SKVSTIWWSDTLST----ALSPSSLPPKI---------STAFHTQQSEGAETTGRPHERS 469
Query: 1500 PSSPELNNKCLTPQRERS--GSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER- 1556
SP ++ + T + S SS T ++T L S +++ + PS
Sbjct: 470 SFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTI 529
Query: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
S + + P S S + P+ + +G++ E A + S
Sbjct: 530 PRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGE------ALLSSPS 583
Query: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS--STESSPEHPPKSRTARRGSRS 1674
S + A +P + P R S PS S+ ST +SP+ P ++RG
Sbjct: 584 YSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPA--VSQRGHTQ 641
Query: 1675 SPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS-- 1732
+P+ +S+T +RS +T ++ S ++S + S P+ +P++S+
Sbjct: 642 APQTTQESQT------TRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQD--APTISAAT 693
Query: 1733 ---PEPAEKSRSSRRR----RSASSPRTKTTSRRGRSPSPK----------------PRG 1769
P P +++ ++A S T G + K P G
Sbjct: 694 TFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEG 753
Query: 1770 LQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQE 1829
S S S T S S + Q S S +R G+ +P+
Sbjct: 754 QWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTA----TPSSSG 809
Query: 1830 SSRTSSRRRRGRSRTPPTSRKRSR-SRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
+S T+ G S + T+R S SR S + ++ A+H T + S
Sbjct: 810 ASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASS--- 866
Query: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR- 1947
P + + S S T R ++SP S S T ++R RT T+R
Sbjct: 867 ---IVPGTFHPTLSEAS-TAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTI 922
Query: 1948 ----------SRTPPVTRR-RSRSRTPPVTRRRSRSRTSP----ITRRRSRSRTSPVTRR 1992
S PP S T P T + S + T S + PVT
Sbjct: 923 SLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYA 982
Query: 1993 RSRS--RTSP--VTRRRSRSR--------TSPVTRRRSRSRTPPAIRRRSRSR---TPLL 2037
S S T+P VT S S TSP + + P S S TPL
Sbjct: 983 SSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLP 1042
Query: 2038 PRKRSRSRS----PLAIRRRSRSRT------PRTARGKRSLTRSPPAIRRRSASGSSSDR 2087
S + + PL + S + T P T+ S + P + S +S+
Sbjct: 1043 VTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTP-LPVTDTSSASTGH 1101
Query: 2088 SRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLG------- 2140
+ S T + S T P+ + + + + P S G PL
Sbjct: 1102 ATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSA 1161
Query: 2141 --SSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPS 2198
TP+ V + S+ G +P +S HA + ++ S G A P P
Sbjct: 1162 STGQATPLPVTSLS--SVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPV 1219
Query: 2199 MSAAGLAA-RMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLA 2257
A+ ++ + +P +P +A + + +P ++ + A +L
Sbjct: 1220 TDASSVSTDHATSLPVTIP-----SAASTGHTTPLPVTDTSSASTGQA--------TSLL 1266
Query: 2258 DSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSG-T 2316
+ T + + P T+ + ++ P T+P+ G TP + +LS +G T
Sbjct: 1267 VTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDT 1326
Query: 2317 PPTAANYPSSSRTPQA-PASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPAL 2375
P PSS+ T P S T P+++ + +A+ L ++
Sbjct: 1327 MPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVS 1386
Query: 2376 SGANLTSPRVPLSAYERVSGRTSPPLLDRARSR-----TPPSAPSQSRMTSERAPSPSSR 2430
+G T+P S +G +P L+ S TP S ++++ A S
Sbjct: 1387 TGD--TTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVT 1444
Query: 2431 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDH 2490
+ A S P P + SA + Q+ L+ T + + V +T+S++ H
Sbjct: 1445 IPSAASTGHTTPL---PVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGH 1501
Query: 2491 NGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRS-----SSSSSSSSSSSSS 2545
L V +P ASTG P + +L A + +S SS+S+ ++
Sbjct: 1502 VTPLHVTSPS---------SASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTP 1552
Query: 2546 SSSSSSSSSSSG----------SSSSDSEGSSLPVQPEVALKR---VPSPTPAPKEAVRE 2592
+ +SS S+G SS+S + LPV + + P P +P A
Sbjct: 1553 LPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTG 1612
Query: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
P P +SS+S+ ++ +++SS S+ ++ +S SS+S+ ++P P
Sbjct: 1613 HTTPLPV-----TDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPV 1667
Query: 2653 KPGPQALPKPASP 2665
A A+P
Sbjct: 1668 TSTSSASTGHATP 1680
Score = 117 bits (294), Expect = 1e-25
Identities = 405/1863 (21%), Positives = 643/1863 (34%), Gaps = 282/1863 (15%)
Query: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP-----SRVTSRTTPRRSRSVSPC 956
+TP + + S+S +++ +G ++P P S T TP S S
Sbjct: 1454 TTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSA 1513
Query: 957 SNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ------------TP 1004
S + LP S S +S+ DT P T P + +G +P P A T
Sbjct: 1514 STGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTS 1573
Query: 1005 PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESY-FGVSSLQLKGQSQT 1063
P + +G +P P D+ S + L SS G + V+ T
Sbjct: 1574 PSSASTGHTTPLPVT---DTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDT 1630
Query: 1064 SP---DHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGE 1120
+P + S S+ H SPS S +P PVT +S S
Sbjct: 1631 TPLPVTNASSLSTGHATPLHVTSPSSASTGHATPL--------PVTSTSSASTGH----- 1677
Query: 1121 FSASPMLKSGMSPEQSRFQSDSSSYPTVD-SNSLLGQSR------LETAESKEKMALPPQ 1173
A+P+ +G+S S D++ P D S++ GQ+ L + + + LP
Sbjct: 1678 --ATPLPVTGLS---SATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVT 1732
Query: 1174 EDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSS 1233
++AS SP V D +S L P + S ++ T + L ++S
Sbjct: 1733 SPSSASTGHA----SPLLVTDASSASTGQATPL--PVTDTSSVSTAHATPLPVTGLSSAS 1786
Query: 1234 QDEEL-MEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQAS 1292
D+ + V + S GQ + + ST + P + A S +
Sbjct: 1787 TDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSA-------STGDTT 1839
Query: 1293 LEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSF----GSPLEFRNSGPLG-TEMNTGF 1347
V +PS ASS G P S S S S + ++ PL T+ N+
Sbjct: 1840 SLPVTIPSSASS-GHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSAS 1898
Query: 1348 SSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVL 1407
+ + T P L + + S+ S+GH++S ++S S S+
Sbjct: 1899 TGD--------------TTP-LHVTDASSVSTGHATS---------LPVTSLSSASTGDT 1934
Query: 1408 DAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMK 1467
+P T SS ++P LP T + +G + L P + S S+
Sbjct: 1935 TPLPVTSPSSASSGHTTP-----LPVTDASSVPTGHATSL------PVTDASSVSTGHAT 1983
Query: 1468 DIPRTPSRGRSECDSSPEP-------KALPQTPRPRSRSPSSPELNNKCLTPQRERSGSE 1520
+P T + S ++P P TP P + S SS + P + S +
Sbjct: 1984 PLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVT-SLSSASTGDTTPLPVTDTSSAS 2042
Query: 1521 SSVDQKTVARTPLGQRSRSG-SSQELDVKPSASPQERSESDSSP-----DSKAKTRTPLR 1574
+ D TPL S S S+ + P SP S ++P S T
Sbjct: 2043 TGQD------TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATS 2096
Query: 1575 QRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPR 1634
SS + L + S S+ + P +P + S D++P P
Sbjct: 2097 LLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTG 2156
Query: 1635 RSRS------GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688
+ S S+S G S + ++ +S H S S+ + T P
Sbjct: 2157 HATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSS 2216
Query: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
S+ + L L + SAS+ T S ++P P + S +
Sbjct: 2217 ASTGHAIPL-----LVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHAT 2271
Query: 1749 SSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRS 1808
S P T +S +P P S S T SS ST
Sbjct: 2272 SLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVT-----DASSASTGHATPLP---- 2322
Query: 1809 RVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP---PTSRKRSRSRTSPAPWKRSR 1865
VT +G + P SS ++ TP + S T+P P S
Sbjct: 2323 -VTSLSSASTGDTTPLPVTSPSSASTGHA------TPLHVTDASSVSTGDTTPLPVTSSS 2375
Query: 1866 SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS 1925
S +S T TPL PV+ S S T +S + +
Sbjct: 2376 SASSGHT-------TPL-----------PVTDASSASTGDTTPLPVTDTSSASTGHATHL 2417
Query: 1926 RTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSR---TP-PVTRRRSRSR--TSPI-- 1977
PVT S S TTR PVT S S TP PVT S S T+P+
Sbjct: 2418 ---PVTGLSSASTGDTTRL-------PVTNVSSASTGHATPLPVTSTSSASTGDTTPLPG 2467
Query: 1978 --TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTP 2035
T S T+P+ + S ++ T R PVT S S T
Sbjct: 2468 TDTSSVSTGHTTPLLVTDASSVSTGDTTRL------PVTSPSSAST----------GHTT 2511
Query: 2036 LLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSL-TRSPPAIRRRSASGSSSDRSRSATPP 2094
LP + S S + TP SL TR ++ S S +S+ + S
Sbjct: 2512 PLPVTDTPSAS-------TGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVT 2564
Query: 2095 ATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLG---------SSRTP 2145
T S P+ + S+ + + P S G PL TP
Sbjct: 2565 DTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTP 2624
Query: 2146 MSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLA 2205
+ V + S G +P +SV HA + ++ S G P P A+ ++
Sbjct: 2625 LPVTDTSSAST--GHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVS 2682
Query: 2206 ARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAA 2265
+ S+ T A +L IP++++ S T +P + D+ + +
Sbjct: 2683 TGHATSLPVTDASSVFTGHATSLPVTIPSSAS------SGHTTPLP----VTDASSVSTG 2732
Query: 2266 AAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSG-TPPTAANYP 2324
A +L P T + + A P T + G TP L +LS +G T P
Sbjct: 2733 HATSL--PVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDT 2790
Query: 2325 SSSRTPQA-PASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
SS+ T QA P + S T P+ + + +A+ SL + A +G P
Sbjct: 2791 SSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLP 2850
Query: 2384 RVPLSAYER---------------VSGRTSPPLLDRARSRTPPSAP-----SQSRMTSER 2423
S+ + TS P+ D + T + P S T
Sbjct: 2851 DTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHA 2910
Query: 2424 APSP-----SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP--VAGSQSLS 2476
P P S+ G A + P+ P +D S TP V S+S
Sbjct: 2911 TPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVS 2970
Query: 2477 SG---AVATTTSSAGDHNGMLSVPAPGVPHSDVGE----PPASTGAQQPSALAALQPAKE 2529
+G + T+ S+ +P + G+ P ST + L P +
Sbjct: 2971 TGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPL-PVTD 3029
Query: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSS---GSSSSDSEGSSLPVQ-PEVALKRVPSPTPA 2585
S+S+ ++ +S SS S+ ++ S SS S G + P+ + + TP
Sbjct: 3030 TSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPL 3089
Query: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSSSS 2643
P ++ + TP SS+S+ ++S + +SS+S+ ++S + +SS+ +
Sbjct: 3090 PVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGD 3149
Query: 2644 SSS 2646
++S
Sbjct: 3150 TTS 3152
Score = 113 bits (282), Expect = 3e-24
Identities = 427/1991 (21%), Positives = 682/1991 (34%), Gaps = 289/1991 (14%)
Query: 854 SITSPQANEQSVT-PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS-- 910
S ++ QA VT P S +++P P + + S + S P + SS + S
Sbjct: 1800 SASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTT-SLPVTIPSSASSGHTTSLP 1858
Query: 911 ----RSSSPQPKVKAIISPRQRSHSGSSSPSP-----SRVTSRTTPRRSRSVSPCSNVES 961
S S +++ +G ++P P S T TTP S S +
Sbjct: 1859 VTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHA 1918
Query: 962 RLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT-PPGPSLS---------- 1010
LP S S +S+ DT P T P + SG +P P A + P G + S
Sbjct: 1919 TSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVS 1978
Query: 1011 -GSKSPCP-QEKSKDSLVQSCPGSLSLCAGVKS--STPPGESYFGVSSLQLKGQSQTSPD 1066
G +P P + S S + P ++ + V + +TP V+SL T+P
Sbjct: 1979 TGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATP-----LPVTSLSSASTGDTTPL 2033
Query: 1067 HRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPM 1126
+DTSS Q + S S S+ T L SP G A+P+
Sbjct: 2034 PVTDTSSASTGQDTPLPVTSLS----------SVSTGDTTPLPVTSPSSASTGH--ATPL 2081
Query: 1127 LKSGMSP-----EQSRFQSDSSSYPTVDSNSL--LGQSRLETAESKEKMALPPQE----D 1175
L + S S +D+SS T + +L S L T ++ P D
Sbjct: 2082 LVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGD 2141
Query: 1176 ATASPPRQKDKFS-----PFPVQDRPESSLVFKDTLRTPPRERSGAG---------SSPE 1221
T P S PV D +S +L + G +S
Sbjct: 2142 TTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSA 2201
Query: 1222 TKEQNSALPTSSQDEEL------MEVVEKSEEPAGQILSHLSSELKEMSTSNFESSP--- 1272
+ Q + LP +S + V + S GQ + L ST + P
Sbjct: 2202 STGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTD 2261
Query: 1273 --EVEERPAVSLTLDQSQSQASLEAVEVP-SMASSWGGPHFSPEHKELSNSPLRENSFGS 1329
V A SL + S ++ + +P + SS H +P H ++S ++
Sbjct: 2262 ASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPL 2321
Query: 1330 PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHS------- 1382
P+ +S G +T P L + S+ S+GH+
Sbjct: 2322 PVTSLSSASTG-----------------------DTTP-LPVTSPSSASTGHATPLHVTD 2357
Query: 1383 SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSG 1442
+S +S ++S+ S SS +P T + S+ ++P LP T + + +G
Sbjct: 2358 ASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTP-----LPVTDTSSASTG 2412
Query: 1443 ----------SSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT 1492
SS D + P + S S+ +P T + S D++P P
Sbjct: 2413 HATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLP------ 2466
Query: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV--KPS 1550
+ ++ TP S S T + +G + L V PS
Sbjct: 2467 ------GTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPS 2520
Query: 1551 ASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA 1610
AS + + + S TR S SS + L + + S+ P
Sbjct: 2521 ASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVT 2580
Query: 1611 APRAQSGSDSSPEPKAPAPRA-------LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
+ + S D++P P A LP S +S+ P P +S+ S+ P
Sbjct: 2581 STSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATP 2640
Query: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET-RSRTPP 1722
T S S+ T P S+ + L S + A+S P T S
Sbjct: 2641 LPVT-NTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFT 2699
Query: 1723 RHRRS-----PSVSS-----PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR 1772
H S PS +S P P + S + S P T +S +P P
Sbjct: 2700 GHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDAS 2759
Query: 1773 SRSRSRREKTRTTRRRDRSGSSQS------TSRRRQRSRSRSRVTRRRRGGSGYHSRSPA 1826
S S T S + TS + VT +G + P
Sbjct: 2760 SVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPV 2819
Query: 1827 RQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR 1886
SS ++ G + + P + S S P + + ++ H T S
Sbjct: 2820 TDTSSAST-----GHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSAS 2874
Query: 1887 RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS--------- 1937
+ + PV+ S S T SP S + PVT S S
Sbjct: 2875 IGHATSLPVTDTSSISTGHATPLHV---TSPSSASTGHATPLPVTDTSSASTGHANPLHV 2931
Query: 1938 RTPTTRRRSRSRTPPVTRRRSRS---RTP-PVTRRRSRSR--------TSPITRRRSRSR 1985
+P++ + PVT S S TP PVT S S TSP + +
Sbjct: 2932 TSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTT 2991
Query: 1986 TSPVTRRRSRS----RTSPVTRRRSRSRTS----PVTRRRSRS---RTP---PAIRRRSR 2031
PVT S S PVT S S PVT S S TP ++ S
Sbjct: 2992 PLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVST 3051
Query: 2032 SRTPLLPRKRSRSRS-----PLAIRRRSRSRT------PRTARGKRSLTRSPPAIRRRSA 2080
T LP S S PL + S + T P T+ S + P
Sbjct: 3052 GDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPL---PVT 3108
Query: 2081 SGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLG 2140
S SS+ + + P T S S +L + S + P+ S
Sbjct: 3109 SPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSST----- 3163
Query: 2141 SSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMS 2200
TP+ V + + S+ G + +S HA + ++ S G P P
Sbjct: 3164 GDTTPLLVTETS--SVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTD 3221
Query: 2201 AAGLAARMSQVPAPVPLMSLRTAPAANLASRIP------AASAAAMNLASARTPAIPTAV 2254
+ ++ + P+P+ L +A + +R+P A++ A L T ++ T
Sbjct: 3222 TSSVSTGHA---TPLPVTGLSSASTGD-TTRLPVTDISSASTGQATPLPVTNTSSVSTGD 3277
Query: 2255 NLADSRTPAAAAAMNLASPR--TAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLT 2312
+ T ++A+ A+P T+ + ++ A P T+ + G TP + S
Sbjct: 3278 TMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSA 3337
Query: 2313 GSG-TPPTAANYPSSSRTPQAPASANLVGPRSAH----ATAPVNIAGSRTAAALAPASLT 2367
+G T P PSS+ T ++ P SA +T PV A S + P +T
Sbjct: 3338 STGDTTPLPVTSPSSASTGHT-TPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVT 3396
Query: 2368 SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP 2427
++S + T +P+++ VS + PL P + S T + P P
Sbjct: 3397 D---TSSVSTGHATP--LPVTSLSSVSTGDTTPL---------PVTDASSASTGQATPLP 3442
Query: 2428 SSRMGQAPSQSLLPPAQDQPRS-----PVPSAFSDQSRCLIAQTT--PVAGSQSLSSG-- 2478
+ + + P S P +D S TT PV + S S+G
Sbjct: 3443 VTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQA 3502
Query: 2479 ----AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSS 2534
+ ++ S GD +L A V P + + + P + S+S
Sbjct: 3503 TPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSAS 3562
Query: 2535 SSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594
+ ++ + SSSSS ++ +S S S+ V P V SP+ A V
Sbjct: 3563 TGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTP----LHVTSPSSASTGHV---- 3614
Query: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654
P P +SS+S+ ++ + +SS S+ ++ + +SS+S+ ++P P
Sbjct: 3615 --TPLPV---TSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTD 3669
Query: 2655 GPQALPKPASP 2665
A A+P
Sbjct: 3670 TSSASTGQATP 3680
Score = 109 bits (272), Expect = 4e-23
Identities = 447/2097 (21%), Positives = 715/2097 (34%), Gaps = 302/2097 (14%)
Query: 669 SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728
S T A G+S + + + S + + +++S + ++ + T SS
Sbjct: 46 STGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTETTSKAQTDTLTQMMTSTLFSSP 105
Query: 729 ERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQ 788
N T+ + S P + + + + + + S +G+
Sbjct: 106 SVHNVMETAPPDEMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAGT------ 159
Query: 789 KSQTPPRRSRSGSSQPKAKSRTPPRRSR----SSSSPPPKQKSKTPSRQSHSSSSPHPKV 844
+S TP + S ++ + +SRT R+ S+SS +S +R+S +S+ H
Sbjct: 160 ESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRT- 218
Query: 845 KSGTPPRQGSI----------TSPQA-----------NEQSVTPQRRSCFESSP----DP 879
+ TP S+ TSP N +T ++ + S+ +P
Sbjct: 219 -TSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNP 277
Query: 880 ELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS 939
S P S + + + P QSP+ S + S ++ S ++
Sbjct: 278 GETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETT---- 333
Query: 940 RVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKV 999
RV+ T V+ + + S ++ SG+ S +T ET S S+S V
Sbjct: 334 RVSQINTLNTLTPVTTSTVLSSP--SGFNPSGTVSQETFPSGETTT--SSPSSVSNTFLV 389
Query: 1000 KAQTPPGPSLSGSKSPCPQEKSKD---------SLVQSCPGSLSLCAGVKSSTPPGESYF 1050
++ P+ S +E S S V + S +L + S+ P +
Sbjct: 390 TSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKIST 449
Query: 1051 GVSSLQLKGQSQTSPDHRSDTSSPEVRQS----HSESP---SLQSKSQT--SPKGGRSRS 1101
+ Q +G T H + SP V Q H + S SK T S S S
Sbjct: 450 AFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTS 509
Query: 1102 SSPVTELASRSPIRQDRGEFSASPMLKS--GMSPEQSRFQSDSSSYPTVDSNSLLGQSRL 1159
+ T L + +P G P S G E + + S S++ P Q
Sbjct: 510 TGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQ 569
Query: 1160 ETAESKEKMALPP-----QEDATASPPRQK---DKFSPFPVQDRPESSLVFKDTLRTPPR 1211
ET + E + P Q TA+ P D+ + + P ++ + T P+
Sbjct: 570 ETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQ 629
Query: 1212 E-----RSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTS 1266
E + G +P+T +++ + S + V H SE+
Sbjct: 630 ESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTAS--GHSPSEIVPQDAP 687
Query: 1267 NFESSPEVEERPAVSLTLDQSQSQASLEAVEV-PSMASSWGGPHFSPEHKELSNSPLREN 1325
++ P T D +QA A++ PS + GP + L +
Sbjct: 688 TISAATTFAPAP----TGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANS 743
Query: 1326 SFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSE 1385
+P GP G T S + + H+
Sbjct: 744 VVSTP-----GGPEGQW----------------------TSASASTSPDTAAAMTHTHQA 776
Query: 1386 LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSP 1445
S +A + S S S A TPS +S ++P +G+ T +R S+P
Sbjct: 777 ESTEASGQTQTSEPASSGSRTTSAGTATPSSS-GASGTTPSGSEGIS-TSGETTRFSSNP 834
Query: 1446 GLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPEL 1505
RD T S L +S IP + S + P + R SSP
Sbjct: 835 S-RDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSP-- 891
Query: 1506 NNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV---KPSASPQERSESDSS 1562
+ +PQ + S + Q+T RT G + S +SQ D P P S +S
Sbjct: 892 TSPSASPQETAAISRMAQTQRT--RTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTS 949
Query: 1563 PDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV-KDKPRAAPRAQSGSDSS 1621
P ++ T +P S SG + S +P SS P A S S
Sbjct: 950 PQTETHTLSP----SGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGH 1005
Query: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681
P LP S S S+ P P +S+ES+ P T S SS
Sbjct: 1006 ATP-------LPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVT----SFSSASTGDS 1054
Query: 1682 SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS 1741
+ P SS S+ +T L S S++S+ +T +P P + S
Sbjct: 1055 TPLPVTDTSSASTGHVTP---LPVTSLSSASTGDT---------------TPLPVTDTSS 1096
Query: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRR 1801
+ + S P T T+S +P P S S T SS ST
Sbjct: 1097 ASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVT-----DTSSVSTGHT- 1150
Query: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPW 1861
+ VT +G + P SS S T+P P
Sbjct: 1151 ----TPLHVTDASSASTGQATPLPVTSLSSV-------------------STGDTTPLPV 1187
Query: 1862 KRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRR 1921
SP++ + TPL+ S + T + +SV+ + S +
Sbjct: 1188 ------TSPSSASTGHA-TPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSA 1240
Query: 1922 RSRSRTPP--VTRRRSRSR--------TPTTRRRSRSRTP-PVTRRRSRSRTPPVTRRRS 1970
S T P VT S S T T+ + TP PVT S S T VT
Sbjct: 1241 ASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAS-TGHVTPLHV 1299
Query: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSR--------TSPVTRRRSRSRTSPVTRRRSRSR- 2021
TSP + + PVT S S TSP + + PVT S S
Sbjct: 1300 ---TSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTG 1356
Query: 2022 --TPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT------PRTARGKRSLTRSPP 2073
TP + S + T +PL + S T P T+ S + P
Sbjct: 1357 HTTPLHVTDASSASTG--------QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP 1408
Query: 2074 AIRRRSASGSSSDRSRSATP-PATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRS 2132
+ ++S S+ ATP P T S S +L + S S +P P+ S
Sbjct: 1409 LLVTDTSSASTGH----ATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSS 1464
Query: 2133 PGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGT 2192
S+ S+L S+ G +P +S H + ++ S G
Sbjct: 1465 -------ASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGH 1517
Query: 2193 ARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPA-ANLASRIPAASAAAMNLASARTPAIP 2251
A P P S + A+ +P PV T+P+ A+ P A ++++ T +P
Sbjct: 1518 ATPLPVTSLSS-ASTGDTMPLPV------TSPSSASTGDTTPLPVTDASSVSTGHTTPLP 1570
Query: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLAD--PRTPTAPAVNLAGARTPAALAAL 2309
T ++A+ +P S+ + D P T+P+ G TP +
Sbjct: 1571 V--------TSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDT 1622
Query: 2310 SL--TGSGTPPTAANYPSSSRTPQAPASANLVGPRSA---HATA-PVNIAGSRTAAALAP 2363
S TG TP N S S P ++ P SA HAT PV S + P
Sbjct: 1623 SSASTGDTTPLPVTNASSLSTGHATPL--HVTSPSSASTGHATPLPVTSTSSASTGHATP 1680
Query: 2364 ASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER 2423
+T S + R+P++ S + PL P S T +
Sbjct: 1681 LPVTGLS-----SATTDDTTRLPVTDVSSASTGQATPL---------PVTSLSSVSTGDT 1726
Query: 2424 APSP-----SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSG 2478
P P S+ G A + + P +D S A TP+ + S+
Sbjct: 1727 TPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSAS 1786
Query: 2479 AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSS 2538
TT D + + A +P ASTG P P + S+S+ +
Sbjct: 1787 TDDTTRLPVTDVSSASTGQA--IPLPVTSPSSASTGDTTPL------PVTDASSASTGDT 1838
Query: 2539 SSSS----SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594
+S SS+SS ++S + +SS + ++ + + + TP P
Sbjct: 1839 TSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSAS 1898
Query: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
+ TP +SS S+ ++S +S SS+S+ ++ +S SS+SS ++P P
Sbjct: 1899 TGDTTPL-HVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLP 1954
Score = 101 bits (252), Expect = 9e-21
Identities = 417/1997 (20%), Positives = 688/1997 (34%), Gaps = 293/1997 (14%)
Query: 762 LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP 821
++SP S + + SS + P S S SS T P +SS
Sbjct: 2339 VTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASS-----GHTTPLPVTDASSA 2393
Query: 822 PPKQKSKTPSRQSHSSSSPH----PKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSP 877
+ P + S+S+ H P + + P N S + + +
Sbjct: 2394 STGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTS 2453
Query: 878 DPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP- 936
+ + + +S +TP + + S S + ++ + +G ++P
Sbjct: 2454 TSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPL 2513
Query: 937 ----SPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992
+PS T TTP + S S + L S S +S+ P T + +G
Sbjct: 2514 PVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGH 2573
Query: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052
+P P T + +G +P P D+ S + L SS G++
Sbjct: 2574 ATPLPV----TSTSSASTGDTTPLPVT---DTYSASTGQATPLPVTDTSSASTGDT---- 2622
Query: 1053 SSLQLKGQSQTSPDHR--------SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSP 1104
+ L + S S H S S+ H SPS S T+P P
Sbjct: 2623 TPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPL--------P 2674
Query: 1105 VTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYP-TVDSNSLLGQSR----- 1158
VT+ +S S G ++ P+ + S F ++S P T+ S++ G +
Sbjct: 2675 VTDASSVST-----GHATSLPVTDAS-----SVFTGHATSLPVTIPSSASSGHTTPLPVT 2724
Query: 1159 -LETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPE--------------SSLVFK 1203
+ + +LP + ++ S +P PV D SS+
Sbjct: 2725 DASSVSTGHATSLPVTDASSVSTGHA----TPLPVTDASSVSTGHATPLPLTSLSSVSTG 2780
Query: 1204 DTLRTPPRERSGAGSSPETKEQNSALPT-SSQDEELMEVVEKSEEPAGQILSHLSSELKE 1262
DT P + S A + T ++L + S+ D + V + S G S ++
Sbjct: 2781 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSS 2840
Query: 1263 MSTSNFESSPEVEERPAVS-----LTLDQSQSQASLEAVEVP-SMASSWGGPHFSPEHKE 1316
ST + P+ + A + L + + S + A +P + SS H +P H
Sbjct: 2841 ASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVT 2900
Query: 1317 LSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQST 1376
+S ++ P+ +S +TG ++ + + P L + + S+
Sbjct: 2901 SPSSASTGHATPLPVTDTSSA------STGHANPLH--VTSPSSASTGHATPLPVTDTSS 2952
Query: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
S+GH++ ++S S+S+ +P T S+ ++P LP T +
Sbjct: 2953 ASTGHATP---------LPVTSLSSVSTGDTTPLPVTSPSSASTGHTTP-----LPVTDT 2998
Query: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKAL------- 1489
+ +G + L P + S S+ +P T + S ++P P
Sbjct: 2999 SSASTGQATAL------PVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTG 3052
Query: 1490 PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKP 1549
TP P + SPSS + TP S +S Q T PL S S S D P
Sbjct: 3053 DTTPLPVT-SPSSASTGHA--TPLLVTDASSASTGQAT----PLPVTSLSSVSTG-DTTP 3104
Query: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR-----SGSSPEV 1604
S S S T T + S P D+ S + + + SS
Sbjct: 3105 LPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTG 3164
Query: 1605 KDKPRAAPRAQSGSDSSPEP-------KAPAPRALPRR--SRSGSSSKGRGPSPEGSSST 1655
P S S P A A P S S +S+ P P +S+
Sbjct: 3165 DTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSS 3224
Query: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS---- 1711
S+ P T SS +R P SS S+ + T + S S
Sbjct: 3225 VSTGHATPLPVTGL----SSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMP 3280
Query: 1712 ------SSPETRSRTPPRHRRSPSVSS----PEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761
SS T TP + S S+ P P + S+ + P T T+S
Sbjct: 3281 LPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTG 3340
Query: 1762 SPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYH 1821
+P P S S TT SS ST S VT +G+
Sbjct: 3341 DTTPLP-----VTSPSSASTGHTTPLHVTIPSSASTG-----DTSTLPVTGASSASTGHA 3390
Query: 1822 SRSPARQESSRTSSRRRRGRSRTPPTSRKR-SRSRTSPAPWKRSRSRASPATHRRSRSRT 1880
+ P SS ++ + P TS S T+P P + A+ + T
Sbjct: 3391 TPLPVTDTSSVSTGHA----TPLPVTSLSSVSTGDTTPLP-------VTDASSASTGQAT 3439
Query: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
PL S T + +SV S A+P+ PVT S S
Sbjct: 3440 PLPVTSLSSVSTGDTTPLLVTDASSV----STGHATPL----------PVTDTSSASTGD 3485
Query: 1941 TTRRRSRSRTPPVTRRRSRSR---TP-PVTRRRSRSR--TSPI----TRRRSRSRTSPVT 1990
TTR PVT S S TP PVT S S T+P+ S +P+
Sbjct: 3486 TTRL-------PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLP 3538
Query: 1991 RRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS---- 2046
+ S ++ T R + TS + ++ S T LP + S S
Sbjct: 3539 VTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHV 3598
Query: 2047 -PLAIRRRSRSRT------PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
PL + S + T P T+ S + P + ++S S+ + A+
Sbjct: 3599 TPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSAS 3658
Query: 2100 SGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSS---------RTPMSVLQ 2150
+G TP ++S S + T L S G PL + TP+ V
Sbjct: 3659 TGDTTPLPVTDTSSASTGQATPLPVTSLSSV-STGDTTPLPVTDASSASTGHATPLPVTI 3717
Query: 2151 QAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQ 2210
+ S+ G +P +S HA L++ S G P P + + R +
Sbjct: 3718 PS--SVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHA- 3774
Query: 2211 VPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSR---------T 2261
P+P+ +A + +R+P ++ + A TP T+ + A + T
Sbjct: 3775 --TPLPVTDTSSASTDD-TTRLPVTDVSSASTGHA-TPLPVTSTSSASTGDTTPLPVTDT 3830
Query: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSG-TPPTA 2320
+ + + P T+ + ++ A P T + G TP + + S +G P
Sbjct: 3831 SSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLP 3890
Query: 2321 ANYPSSSRTPQA---PASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSG 2377
PSS+ T A P ++ PV A S + P +TS P+ +
Sbjct: 3891 VTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTS----PSSAS 3946
Query: 2378 ANLTSPRVPLSAYERVSGRTSP-PLLDRARSRTPPSAP-----SQSRMTSERAPSPSSRM 2431
TS A +G +P PL + T + P + S T + P P + +
Sbjct: 3947 RGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSL 4006
Query: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSG------AVATTTS 2485
+ P P + SA S + L PV + S+S+G +T+++
Sbjct: 4007 SSVSTGDTTP----LPVTIPSSASSGHTTSL-----PVTDASSVSTGHGTPLPVTSTSSA 4057
Query: 2486 SAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS 2545
S GD + P P S ASTG P P + S+S+ ++ +S
Sbjct: 4058 STGD-----TTPLPVTDTSS-----ASTGHATPL------PVTDTSSASTGHATPLPVTS 4101
Query: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
SS S+ ++ + SS + S++ + ++ TP+ K P P +
Sbjct: 4102 LSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQT 4161
Query: 2606 RSSSSSSSSSSSSSSSS 2622
S+ S++ + S+++
Sbjct: 4162 IISTIPSTAMHTRSTAA 4178
Score = 73.2 bits (178), Expect = 3e-12
Identities = 251/1125 (22%), Positives = 396/1125 (35%), Gaps = 198/1125 (17%)
Query: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP-----SRVTSRTTPRRSRSVSPCS 957
T P + + ++P P ++ +G ++P P S T TT +S S
Sbjct: 3204 TSPSSASTGDTTPVP-----VTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSAS 3258
Query: 958 NVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCP 1017
++ LP + S S+ DT P T P + +G +P P T + +G +P P
Sbjct: 3259 TGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPV----TSTSSASTGHATPVP 3314
Query: 1018 QEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVR 1077
+ + S + L SS G++ + L + S S H +
Sbjct: 3315 VTSTSSA---STGHTTPLPVTDTSSASTGDT----TPLPVTSPSSASTGHTTPL------ 3361
Query: 1078 QSHSESPSLQSKSQTS--PKGGRSRSSS------PVTELASRSPIRQDRGEFSASPMLKS 1129
H PS S TS P G S +S+ PVT+ +S S A+P+ +
Sbjct: 3362 --HVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGH-------ATPLPVT 3412
Query: 1130 GMSPEQSRFQSDSSSYPTVDSNSL-------LGQSRLETAESKEKMALPPQEDATASPPR 1182
+S + D++ P D++S L + L + + + L + ++ S
Sbjct: 3413 SLSSVST---GDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGH 3469
Query: 1183 QKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPT-SSQDEELMEV 1241
+P PV D +S DT R P + S A + T ++L + S+ D + V
Sbjct: 3470 A----TPLPVTDTSSAST--GDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLV 3523
Query: 1242 VEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSM 1301
+ S G ++ ST + P V+ T S QA+ V +PS
Sbjct: 3524 TDASSVSTGHATPLPVTDTSSASTGDTTRLP-------VTDTSSASTGQATPLPVTIPSS 3576
Query: 1302 ASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLN 1361
+SS +PL S S ++TG + + + P
Sbjct: 3577 SSSG------------HTTPLPVTSTSS-------------VSTGHVTPLH--VTSPSSA 3609
Query: 1362 QLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSS 1421
L + S+ S+GH++ L DA + +S+ + PV DA SS
Sbjct: 3610 STGHVTPLPVTSTSSASTGHATPLLVTDA---SSVSTGHATPLPVTDA----------SS 3656
Query: 1422 ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECD 1481
AS+ + LP T + + +G + L P S S+ +P T + S
Sbjct: 3657 ASTGDTTP-LPVTDTSSASTGQATPL------PVTSLSSVSTGDTTPLPVTDASSASTGH 3709
Query: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541
++P P +P + ++ P S S +S T TPL S
Sbjct: 3710 ATPLPVTIPSS------------VSTGDTMPLPVTSPSSAS----TGHATPLPVTGLS-- 3751
Query: 1542 SQELDVKPSASPQERSESDSSPDSKAKTR--TPLRQRSRSGSSPEVDSKSRLSPRRSRSG 1599
SAS + + + S A TR TPL S +S D +RL S
Sbjct: 3752 --------SASTGDTTPLPVTDTSSASTRHATPLPVTDTSSAS--TDDTTRLPVTDVSSA 3801
Query: 1600 SSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR-------ALPRRSRSGSSSKGRGPSPEGS 1652
S+ P + + S D++P P +LP SRS +S+ P P
Sbjct: 3802 STGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTD 3861
Query: 1653 SSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA-- 1710
+S+ S+ P T S SS + P SS S+ T S S S
Sbjct: 3862 TSSVSTGHATPLPVT----STSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGD 3917
Query: 1711 -------SSSPETRSRTPPRHRRSPSVSSPE-----PAEKSRSSRRRRSASSPRTKTTSR 1758
++S + P H SPS +S P + S+ + P T +S
Sbjct: 3918 TTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSV 3977
Query: 1759 RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS 1818
+P P S S + T S SS ST + VT S
Sbjct: 3978 STGDTTPLPVTDTSSASTGQATPLPVT-----SLSSVSTG-----DTTPLPVTIPSSASS 4027
Query: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878
G+ + P SS ++ G P + S S P + + ++ H
Sbjct: 4028 GHTTSLPVTDASSVST-----GHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLP 4082
Query: 1879 RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR--SRSRASPVSRRRS-RSRTPPVTRRRS 1935
T S + PV+ S S T S + AS VS + TP +T
Sbjct: 4083 VTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMT---- 4138
Query: 1936 RSRTPTTRRRSRSRT---PPVTRRRSRSRTPPVTRRRSRSRTSPI 1977
TP+ + RT PP T ++ T P T +RS +PI
Sbjct: 4139 ---TPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPI 4180
Score = 48.9 bits (115), Expect = 7e-05
Identities = 63/243 (25%), Positives = 89/243 (36%), Gaps = 37/243 (15%)
Query: 220 SESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS----TSADSASSSDTS 275
+++ S H +P P + S T + H + TS SAS+ DT+
Sbjct: 3860 TDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTT 3919
Query: 276 --RSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSS 333
+ S+ + H T L SPS AS G TST + +A+ ++
Sbjct: 3920 PLPVTNASSLSTGHATPLHVTSPSSAS------------RGDTSTLPVTDASSASTGHAT 3967
Query: 334 PYEDKDKDKKEKSATRPSPSPERS--STGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV 391
P T P P + S STG P P L+ G TTPL PV
Sbjct: 3968 PLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGD-----TTPL---PV 4019
Query: 392 NPPSEASPTRDRSPPKSPEK---------LPQSSSSESSPPSPQPTKVSRHASSSPESPK 442
PS AS S P + LP +S+S +S P V+ +S+S
Sbjct: 4020 TIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHAT 4079
Query: 443 PAP 445
P P
Sbjct: 4080 PLP 4082
Score = 45.8 bits (107), Expect = 6e-04
Identities = 51/209 (24%), Positives = 74/209 (35%), Gaps = 18/209 (8%)
Query: 252 TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFS 311
TP P + TS+ S ++ S S+A+ H T L S AS P +
Sbjct: 2911 TPLPVT-----DTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHAT-PLPVT 2964
Query: 312 EPGTTST--------QRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP 363
+ ST PSS T P P D ++ P S +STG
Sbjct: 2965 SLSSVSTGDTTPLPVTSPSSASTGHTTPL-PVTDTSSASTGQATALPVTSTSSASTGDTT 3023
Query: 364 PAPTPLLAERHGGSPQPLATTPLSQ---EPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
P P + G PL T LS P SP+ + +P + +SS+ +
Sbjct: 3024 PLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSAST 3083
Query: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGS 449
+P P S+ +P P +P S
Sbjct: 3084 GQATPLPVTSLSSVSTGDTTPLPVTSPSS 3112
Score = 43.9 bits (102), Expect = 0.002
Identities = 71/296 (23%), Positives = 101/296 (34%), Gaps = 33/296 (11%)
Query: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277
H + S H +P P + D + TP P TS S S+ DT+
Sbjct: 2930 HVTSPSSASTGHATPLPVT-----DTSSASTGHATPLPV-------TSLSSVSTGDTTPL 2977
Query: 278 --RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSS-- 333
S S+A+ HTT L S AS + S ++ P T T S+
Sbjct: 2978 PVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQ 3037
Query: 334 --PYEDKDKDKKEKSATRPSP--SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
P T P P SP +STG P + G PL T LS
Sbjct: 3038 ATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSV 3097
Query: 390 --------PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441
PV PS AS S P + + + S P + + + +S P +
Sbjct: 3098 STGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTD 3157
Query: 442 KPAPAPGSHREISSSPTSKNRSHGRAK----RDKSHSHTPSRRMGRSRSPATAKRG 493
+ + G + + TS + S G A D S + T SP++A G
Sbjct: 3158 TSSSSTGDTTPLLVTETS-SVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTG 3212
Score = 42.0 bits (97), Expect = 0.008
Identities = 58/252 (23%), Positives = 85/252 (33%), Gaps = 23/252 (9%)
Query: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS----TSADSASSSD 273
H + S H +P P + S T A H + T A SAS+ D
Sbjct: 3602 HVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGD 3661
Query: 274 TSRS--RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP 331
T+ S+A+ T L S S S G T+ + +A+
Sbjct: 3662 TTPLPVTDTSSASTGQATPLPVTSLSSVS------------TGDTTPLPVTDASSASTGH 3709
Query: 332 SSPYEDKDKDKKEKSATRPSP--SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
++P T P P SP +STG P P L+ G PL T S
Sbjct: 3710 ATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSA 3769
Query: 390 PVNPPSEASPTRDRSPPKSPE--KLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAP 447
+ P D S + + +LP + S +S P V+ +S+S P P
Sbjct: 3770 STRHATPL-PVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVT 3828
Query: 448 GSHREISSSPTS 459
+ + TS
Sbjct: 3829 DTSSVSTGHATS 3840
Score = 42.0 bits (97), Expect = 0.008
Identities = 54/246 (21%), Positives = 90/246 (36%), Gaps = 17/246 (6%)
Query: 220 SESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS----TSADSASSSDTS 275
+++ S H +P P + S T + H + T SAS+ DT+
Sbjct: 3700 TDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTT 3759
Query: 276 RS--RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS-PETATKQPS 332
S+A+ H T L S AS P ++ + ST + P T+T S
Sbjct: 3760 PLPVTDTSSASTRHATPLPVTDTSSAS-TDDTTRLPVTDVSSASTGHATPLPVTSTSSAS 3818
Query: 333 S------PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL---AT 383
+ P D + + P S +STG P P + G PL +T
Sbjct: 3819 TGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTST 3878
Query: 384 TPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKP 443
+ +S P SP+ + +P + +SS+ + +P P + S+ +P
Sbjct: 3879 SSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLH 3938
Query: 444 APAPGS 449
+P S
Sbjct: 3939 VTSPSS 3944
Score = 38.5 bits (88), Expect = 0.092
Identities = 48/196 (24%), Positives = 72/196 (36%), Gaps = 27/196 (13%)
Query: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDA---PFSEPGTTSTQR 320
TS+ S + S+A+ H T L SPS AS GD P ++ + ST
Sbjct: 3174 TSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSAS----TGDTTPVPVTDTSSVSTGH 3229
Query: 321 PSS-PETATKQPSS------PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373
+ P T S+ P D ++ P + STG P P
Sbjct: 3230 ATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVT----- 3284
Query: 374 HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRH 433
SP +T + PV S AS +P + +SS+ + +P P +
Sbjct: 3285 ---SPSSASTGHATPLPVTSTSSASTGH-----ATPVPVTSTSSASTGHTTPLPVTDTSS 3336
Query: 434 ASSSPESPKPAPAPGS 449
AS+ +P P +P S
Sbjct: 3337 ASTGDTTPLPVTSPSS 3352
Score = 38.1 bits (87), Expect = 0.12
Identities = 54/199 (27%), Positives = 74/199 (37%), Gaps = 24/199 (12%)
Query: 252 TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDA--- 308
TP P + STS+ S + S S+A+ HTT L S AS GD
Sbjct: 3295 TPLPVT-----STSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSAS----TGDTTPL 3345
Query: 309 PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368
P + P + ST ++P T S+ D ++T P +STG P P
Sbjct: 3346 PVTSPSSASTGH-TTPLHVTIPSSASTGD--------TSTLPVTGASSASTGHATPLPVT 3396
Query: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPE--KLPQSSSSESSPPSPQ 426
+ G PL T LS + P D S + + LP +S S S
Sbjct: 3397 DTSSVSTGHATPLPVTSLSSVSTGDTTPL-PVTDASSASTGQATPLPVTSLSSVSTGDTT 3455
Query: 427 PTKVSRHASSSPESPKPAP 445
P V+ +S S P P
Sbjct: 3456 PLLVTDASSVSTGHATPLP 3474
Score = 36.6 bits (83), Expect = 0.35
Identities = 44/205 (21%), Positives = 77/205 (37%), Gaps = 11/205 (5%)
Query: 264 TSADSASSSDTSR---SRSRSAAAKTHTTALAGRSPSPASGRRGE---GDAPFSEPGTTS 317
T SA + DT+ + + S++ T L + S ++G DA + G +
Sbjct: 3140 TDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHAT 3199
Query: 318 TQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSS--TGPEPPAPTPLLAERHG 375
+SP +A+ ++P D P P SS TG P ++
Sbjct: 3200 PLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSAST 3259
Query: 376 GSPQPLA---TTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR 432
G PL T+ +S P SP+ + +P + +SS+ + +P P +
Sbjct: 3260 GQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTS 3319
Query: 433 HASSSPESPKPAPAPGSHREISSSP 457
AS+ +P P S ++P
Sbjct: 3320 SASTGHTTPLPVTDTSSASTGDTTP 3344
Score = 35.0 bits (79), Expect = 1.0
Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 19/209 (9%)
Query: 264 TSADSASSSDTSRS--RSRSAAAKTHTTALAGRSPSPASGRRGEGDAP---FSEPGTTST 318
T SAS+ DT+R S+A+ T L S S S GD ++ + ST
Sbjct: 3476 TDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVS----TGDTTPLLVTDASSVST 3531
Query: 319 QRPSS-PETATKQPSS------PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLA 371
+ P T T S+ P D ++ P P SS+G P P +
Sbjct: 3532 GHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTS 3591
Query: 372 ERHGGSPQPL-ATTPLSQEP--VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPT 428
G PL T+P S V P S + + +P + +SS + +P P
Sbjct: 3592 SVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPV 3651
Query: 429 KVSRHASSSPESPKPAPAPGSHREISSSP 457
+ AS+ +P P S ++P
Sbjct: 3652 TDASSASTGDTTPLPVTDTSSASTGQATP 3680
Score = 34.3 bits (77), Expect = 1.7
Identities = 79/307 (25%), Positives = 102/307 (33%), Gaps = 72/307 (23%)
Query: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST---------SADSASSSDTSRS-- 277
H +P P + S + TTP P + + ST S SAS DTS
Sbjct: 3901 HATPVPVTSTSSAS-----TGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPV 3955
Query: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDA---PFSEPGTTSTQRP--------SSPET 326
S+A+ H T L S S S GD P ++ + ST + SS T
Sbjct: 3956 TDASSASTGHATPLPLTSLSSVS----TGDTTPLPVTDTSSASTGQATPLPVTSLSSVST 4011
Query: 327 ATKQP---------------SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLA 371
P S P D P S +STG P P +
Sbjct: 4012 GDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTS 4071
Query: 372 ERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVS 431
G PL PV S AS T +P LP +S S S P VS
Sbjct: 4072 SASTGHATPL--------PVTDTSSAS-TGHATP------LPVTSLSSVSTGHATPLAVS 4116
Query: 432 RHASS---SPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPA 488
S+ S +SP PG T ++ G + S T S+ + S P+
Sbjct: 4117 SATSASTVSSDSPLKMETPG-------MTTPSLKTDGGRRTATSPPPTTSQTI-ISTIPS 4168
Query: 489 TAKRGRS 495
TA RS
Sbjct: 4169 TAMHTRS 4175
Score = 33.5 bits (75), Expect = 3.0
Identities = 61/283 (21%), Positives = 91/283 (32%), Gaps = 59/283 (20%)
Query: 220 SESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTS---------ADSAS 270
+ + S H +P P + D + TTP P + + ST SAS
Sbjct: 3316 TSTSSASTGHTTPLPVT-----DTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSAS 3370
Query: 271 SSDTSRS--RSRSAAAKTHTTALAGRSPSPASGRRGE------------GDA---PFSEP 313
+ DTS S+A+ H T L S S GD P ++
Sbjct: 3371 TGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDA 3430
Query: 314 GTTST-QRPSSPETATKQPSS----------------------PYEDKDKDKKEKSATRP 350
+ ST Q P T+ S+ P D + P
Sbjct: 3431 SSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLP 3490
Query: 351 SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPE 410
+STG P P L+ G PL T S + P D S + +
Sbjct: 3491 VTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPL-PVTDTSSASTGD 3549
Query: 411 --KLP--QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
+LP +SS+ + +P P + +SS +P P + S
Sbjct: 3550 TTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSS 3592
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 136 bits (343), Expect = 2e-31
Identities = 169/657 (25%), Positives = 249/657 (37%), Gaps = 102/657 (15%)
Query: 146 VDGSSFDPQRRAREAK-QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSS 204
V G Q RE + Q KP++ VR S PK K KK++K R + S SSS
Sbjct: 140 VFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGEL-IPKSKVKKEEKKRHKSSSSSS 198
Query: 205 PRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST 264
SS + S+S + S T + +K K K RK SR K + R
Sbjct: 199 SSSSDSDSSSDSQSSSDSSDSE----SATEEKSKKRKKKHRKNSRKH----KKEKKKRKK 250
Query: 265 SADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS- 323
S SASS E +A E ST RP
Sbjct: 251 SKKSASS---------------------------------ESEAENLEAQPQSTVRPEEI 277
Query: 324 ---PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERH------ 374
PE SP + +K++K + R ER PP P +R
Sbjct: 278 PPIPENRFLMRKSPPKADEKERKNRERER-----ERECN---PPNSQPASYQRRLLVTRS 329
Query: 375 -----GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK 429
G P+ T S+ +P R + +++ SS
Sbjct: 330 GRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELN 389
Query: 430 VSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489
+ SP K HR +S SP KN + K KS+S R +
Sbjct: 390 EIKENQRSPVRVKERKIT-DHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKY 448
Query: 490 AKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR-SRSPQRRGRSRSPQRPGWS-RSRN 547
+ + KR S+SRS +S+S +R + +R+ ++R RSRS R + + +
Sbjct: 449 KNKVK-------KRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKE 501
Query: 548 TQRRGRSRSARRGRSHSRSPATRGRS------RSRTPARRGRSRSRTPARRRSRSRTPTR 601
Q + + R RS +S +S +S+ RR +SRSR + + +R
Sbjct: 502 KQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSR 561
Query: 602 RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS---RTPARRGRS 658
R RSR+ R R RSRT R RSR++ R R + RR GRSRS RTP R RS
Sbjct: 562 TRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE---YRRRGRSRSRERRTPPGRSRS 618
Query: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP 718
+ R RR R SR+ R +SR++ R S+S + + + + R H+
Sbjct: 619 KDR---RRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHN--- 672
Query: 719 QRRGRSGSSSERKNKSRTSQRRSR---SNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
S ++S K R S+ S+ E+K S + ++ + S K +
Sbjct: 673 -----SSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQK 724
Score = 119 bits (297), Expect = 5e-26
Identities = 154/568 (27%), Positives = 239/568 (42%), Gaps = 85/568 (14%)
Query: 1520 ESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS 1579
+S V ++ R S S SS S S + S+S+S+ + K+K R +++ R
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKR---KKKHRK 236
Query: 1580 GSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPE--PKAPAPRALPRRSR 1637
S K + + + S E ++ AQ S PE P P R L R+S
Sbjct: 237 NSRKHKKEKKKRKKSKKSASSESEAENL-----EAQPQSTVRPEEIPPIPENRFLMRKSP 291
Query: 1638 SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL 1697
+ K R + E E +P + + RR + K K R P R R+
Sbjct: 292 PKADEKER-KNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTP------ 344
Query: 1698 TRKARLSRRSRSASSSPETRSRTPPRHRRSPS------VSSPE---PAEKSRSSRRRRSA 1748
SRS S RS TPP R+ VSS E +KS + + +
Sbjct: 345 ---------SRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQ 395
Query: 1749 SSP----RTKTTSRRGRSPSP-----KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSR 1799
SP K T R S SP K + ++ +S S+ R +D ++ R
Sbjct: 396 RSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKR 455
Query: 1800 RRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR------RRRGRSRTPPTSRKRSR 1853
+ +SRS+S+ + + H+R+ ++ SR+ R + +S + ++RSR
Sbjct: 456 AKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSR 515
Query: 1854 SRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS 1913
S+ K+ S+++ H +S+ + R +SRSR +++ + S S TR RSRS
Sbjct: 516 SKEKS---KQLESKSNEHDHSKSKEKD---RRAQSRSRECDITKGK-HSYNSRTRERSRS 568
Query: 1914 RASPVSRRRSRSRTPPVTRRRS----RSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRR 1969
R RR RSRT R RS R R RRR RSR +R R RTPP
Sbjct: 569 RD---RSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSR----SRER---RTPP----- 613
Query: 1970 SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRR 2029
RSR+ RRR SR+S R S+SR + + R++ S + R+ S + + +
Sbjct: 614 GRSRSKDRRRRRRDSRSS--EREESQSR----NKDKYRNQESKSSHRKENSESEKRMYSK 667
Query: 2030 SR---SRTPLLPRKRSRSRSPLAIRRRS 2054
SR S +K R +SP + ++S
Sbjct: 668 SRDHNSSNNSREKKADRDQSPFSKIKQS 695
Score = 117 bits (292), Expect = 2e-25
Identities = 156/593 (26%), Positives = 230/593 (38%), Gaps = 85/593 (14%)
Query: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
R + KP A R S + P+ K +S S SS SSS
Sbjct: 152 REIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSS----------SSS 201
Query: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
++S +S + S S+ E K+K R R++SR + +K + S++S S+ S
Sbjct: 202 SDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEA 261
Query: 1715 ETRSRTP------------PRHRRSPSVSSPEPAEKSRSSRRR-----------RSASSP 1751
E P P +R S P+ EK R +R R + AS
Sbjct: 262 ENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQ 321
Query: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR--SRSR 1809
R +R GR K RG +R R+ SR +R RDR S++ RQ + R R
Sbjct: 322 RRLLVTRSGR--KIKGRGPRRYRTPSR------SRSRDRFRRSETPPHWRQEMQRAQRMR 373
Query: 1810 VTRRRRGGSGYHS---------RSPARQESSRTSSRRRRGRS---RTPPTSRKRSRSRTS 1857
V+ R G S RSP R + + + R S + + + S
Sbjct: 374 VSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNS 433
Query: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA-- 1915
R S + + R SR +S+ ++ R +R R RSRS+
Sbjct: 434 KERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRD 493
Query: 1916 -SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRT 1974
V + +S + + RSRS+ + + S+S ++ + + R R +SRSR
Sbjct: 494 HENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR-----RAQSRSRE 548
Query: 1975 SPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRS----RSRTPPAIRR-R 2029
IT+ + + TR RSRSR RR RSRT R RS R R RR R
Sbjct: 549 CDITKGKHSYNSR--TRERSRSRD---RSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGR 603
Query: 2030 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSR 2089
SRSR P RSRS+ RR R R R++ + S +R+ R + S S +
Sbjct: 604 SRSRERRTPPGRSRSKD-----RRRRRRDSRSSEREESQSRNKDKYRNQE---SKSSHRK 655
Query: 2090 SATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSS 2142
+ R +S SR NSS S + +P + + L SS
Sbjct: 656 ENSESEKRMYSKSRDH----NSSNNSREKKADRDQSPFSKIKQSSQDNELKSS 704
Score = 103 bits (258), Expect = 2e-21
Identities = 145/651 (22%), Positives = 246/651 (37%), Gaps = 138/651 (21%)
Query: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
PKSK K ++KKR H+S+S+ S+SSSD+ S
Sbjct: 179 PKSKVKKEEKKR---------------HKSSSSSSSSSSDSDSS---------------- 207
Query: 294 RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS 353
S + D+ SE ++T+ S + +S K+K K++KS S
Sbjct: 208 ------SDSQSSSDSSDSE---SATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSE 258
Query: 354 PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLP 413
E AE PQ + + E + P E +SPPK+ EK
Sbjct: 259 SE---------------AENLEAQPQ----STVRPEEIPPIPENRFLMRKSPPKADEKER 299
Query: 414 QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSH 473
++ E R +P + +PA
Sbjct: 300 KNRERE------------RERECNPPNSQPA----------------------------- 318
Query: 474 SHTPSRRMGRSRSPATAK-RGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRG 532
+ RR+ +RS K RG R RTP++ SRSR ++RRS + W + +R
Sbjct: 319 --SYQRRLLVTRSGRKIKGRGPRRYRTPSR---SRSRD-RFRRSETPPHWRQEMQRAQRM 372
Query: 533 RSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARR 592
R S +R W + ++ + R T R+ S +P R+ + +
Sbjct: 373 RVSSGER--WIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHK 430
Query: 593 RSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP 652
+ RR S + + ++R++++S + + +S+S R S +R+
Sbjct: 431 SNSKERDIRRNSEKD-------DKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEK 483
Query: 653 ARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGR 712
R RS+ R ++ ++ + RSR+ + + S++ S+S+ RR +
Sbjct: 484 RMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQ 543
Query: 713 SHSRTPQ-RRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS 771
S SR +G+ +S + +SR+ R R S + R RS S + +
Sbjct: 544 SRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSR--------THDRDRSRSKEYHRYRE 595
Query: 772 RLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS 831
+ RR S S ++ +TPP RSRS K R RR SS Q
Sbjct: 596 QEYRRRGRSRS-----RERRTPPGRSRS-------KDRRRRRRDSRSSEREESQSRNKDK 643
Query: 832 RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELK 882
++ S S H K S + R S S N + + ++++ + SP ++K
Sbjct: 644 YRNQESKSSHRKENSESEKRMYS-KSRDHNSSNNSREKKADRDQSPFSKIK 693
Score = 103 bits (256), Expect = 3e-21
Identities = 134/590 (22%), Positives = 227/590 (38%), Gaps = 82/590 (13%)
Query: 1456 RHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRE 1515
RH S SS + S +S DSS A + + R + +
Sbjct: 190 RHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKK---------------KH 234
Query: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQ 1575
R S +K + S ++ L+ +P ++ + E P+++ R
Sbjct: 235 RKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRP-EEIPPIPENRFLMRK---- 289
Query: 1576 RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRR 1635
S P+ D K R + R R +P + R + S + K PR
Sbjct: 290 -----SPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTP 344
Query: 1636 SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE---PKTKSRTPPRRRSSR 1692
SRS S + R +E+ P + + A+R SS E KS + + R
Sbjct: 345 SRSRSRDRFR--------RSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQR 396
Query: 1693 SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV-------SSPEPAEKSRSSRRR 1745
S + + R+ S S + + + +S S S + K++ +R
Sbjct: 397 SPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRA 456
Query: 1746 RSASSPRTKTTSRRGRSPSPKPRGLQ-RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804
+S S ++K S+ S R + R RSRS+ + +++ S+ + R RS
Sbjct: 457 KSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRS 516
Query: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRR-----RGRSRTPPTSRKRSRSRTSPA 1859
+ +S+ + S H S ++++ R SR R +G+ +R+RSRSR
Sbjct: 517 KEKSKQLESK---SNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRS- 572
Query: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919
+R RSR TH R RSR+ R R + RRR RS RSR R +P
Sbjct: 573 --RRVRSR----THDRDRSRSKEYHRYREQE-----YRRRGRS-------RSRERRTPPG 614
Query: 1920 RRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITR 1979
R RS+ R RRR R + R S+SR + + R++ + R+ S +
Sbjct: 615 RSRSKDR-----RRRRRDSRSSEREESQSR----NKDKYRNQESKSSHRKENSESEKRMY 665
Query: 1980 RRSRSRTSPVTRRRSRS--RTSPVTRRRSRSRTSPVTRRRSRSRTPPAIR 2027
+SR S R ++ SP ++ + S+ + + +++ IR
Sbjct: 666 SKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIR 715
Score = 100 bits (250), Expect = 2e-20
Identities = 130/591 (21%), Positives = 219/591 (37%), Gaps = 40/591 (6%)
Query: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHG 465
PKS K + +SS S + S +S S S + + + E S K+R +
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 466 RAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRT--------PTKRGHSRSRSPQWRRSR 517
R + + S++ S S A + +S P R R P ++
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPP---KAD 295
Query: 518 SAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRT 577
+R R R +R + Q + R R GR R R + R+P+ RSRSR
Sbjct: 296 EKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRY-RTPS---RSRSRD 351
Query: 578 PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS 637
RR S TP R + R R S +G + R SPVR + R
Sbjct: 352 RFRR----SETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQR--SPVRVKERK 405
Query: 638 RSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRS--RTPARRGRSRSR 695
+ R+ S +P R+ + + S+ R R S + +R +S+SR
Sbjct: 406 IT----DHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR 461
Query: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP-EMKKSRI 754
+ + +S+S+ R H+R ++R RS S + +++S S E +S+
Sbjct: 462 SKSKEKSKSKE---RDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKE 518
Query: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK-----SQTPPRRSRSGSSQPKAKSR 809
S++ S S+ +KS+ RR+ S S C K + RSRS + +SR
Sbjct: 519 KSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSR 578
Query: 810 TPPR-RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ 868
T R RSRS +++ +S S P +S + R+ +++E+ +
Sbjct: 579 THDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQS 638
Query: 869 R---RSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISP 925
R + + S K + S S S+ + R SP K+K
Sbjct: 639 RNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698
Query: 926 RQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPD 976
+ S + ++ S +S ++ ++ H S D
Sbjct: 699 NELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTD 749
Score = 94.7 bits (234), Expect = 1e-18
Identities = 128/537 (23%), Positives = 214/537 (39%), Gaps = 52/537 (9%)
Query: 129 EKKNERLRAAFGISDSYVDGSSFDPQRRA--REAKQPAPEPPKPYSLVRESSSSRSPTPK 186
EKK + ++ S S D SS D Q + +++ E K +S + K
Sbjct: 187 EKKRHKSSSSSSSSSSDSDSSS-DSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEK 245
Query: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRK 246
+K+KK KK SE+ + + + + + ++ E++ +SP +++ K+++R+
Sbjct: 246 KKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERE 305
Query: 247 RSR-----STTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASG 301
R R ++ PA RR + S R R+ S ++ + RS +P
Sbjct: 306 RERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPS---RSRSRDRFRRSETPPHW 362
Query: 302 RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP 361
R+ E R SS E K S + ++++ P ER T
Sbjct: 363 RQ--------EMQRAQRMRVSSGERWIKGDKSELNEIKENQRS-----PVRVKERKITDH 409
Query: 362 EPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESS 421
+ +P + S S D+ K ++ S S+S
Sbjct: 410 RNVSESP----NRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSK 465
Query: 422 PPSPQPTKVSRHASSSPESPKPAPAPGSH-----REISSSPTSKNRSHGRAKRDKSHSHT 476
S + S+H + + + H +E S K++ R+K +
Sbjct: 466 EKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 477 PSRRMGRSRSPATAKRGRSRSR--TPTKRGHS-RSRSPQWRRSRSAQRWGRSRSPQR-RG 532
S S+S +R +SRSR TK HS SR+ + RSR R RSR+ R R
Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRS 585
Query: 533 RSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARR 592
RS+ R R + +RRGRSRS R R+P R RS+ R RR R SR+ R
Sbjct: 586 RSKEYHR---YREQEYRRRGRSRSRER-----RTPPGRSRSKDR---RRRRRDSRSSERE 634
Query: 593 RSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS 649
S+SR + R++ + R + S + R S++R S + S +++ R +S
Sbjct: 635 ESQSRNKDKYRNQESKSSHR-KENSESEKRMYSKSRD---HNSSNNSREKKADRDQS 687
Score = 91.7 bits (226), Expect = 9e-18
Identities = 138/569 (24%), Positives = 217/569 (38%), Gaps = 60/569 (10%)
Query: 1372 KEQSTRSSGHSSSELSPDAVEKAGMSSNQSIS---SPVLDAVPRTPSRERSS-------- 1420
K S+ SS S S+ S D+ + S ++S + S R SR+
Sbjct: 192 KSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKS 251
Query: 1421 --SASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRS 1478
SASS + L P R P + P L SP D +R R
Sbjct: 252 KKSASSESEAENLEAQPQSTVRPEEIPPI------PENRFLMRKSPPKADEKERKNRERE 305
Query: 1479 ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSES-SVDQKTVARTPLGQRS 1537
P + P + + R S K P+R R+ S S S D+ + TP R
Sbjct: 306 RERECNPPNSQPASYQRRLLVTRSGR-KIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQ 364
Query: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR 1597
+Q + V S + + + K R+P+R + R + S+S P R +
Sbjct: 365 EMQRAQRMRVS-SGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSES---PNR-K 419
Query: 1598 SGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
+ +VKD + +S + K +S+S S SK + S E S
Sbjct: 420 NEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNR 479
Query: 1658 SPEHPPKSRTARRGSRSSPEPK----TKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS 1713
+ E +SR+ R + E + +K + R RS S +L K S+
Sbjct: 480 NEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESK-----------SN 528
Query: 1714 PETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRS 1773
S++ + RR+ S S K + S R+ R++ SRR RS R R
Sbjct: 529 EHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRS-----RTHDRD 583
Query: 1774 RSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRT 1833
RSRS+ + R G S+S RR RSRS+ RRRR S RS R+ES
Sbjct: 584 RSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDS----RSSEREESQ-- 637
Query: 1834 SSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR---SRSRTPLISRRRSRS 1890
S + + R++ +S ++ S + + +SR S R R ++P ++S
Sbjct: 638 SRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQ 697
Query: 1891 RTSPVS-----RRRSRSRTSVTRRRSRSR 1914
S + + R+SV + +S+
Sbjct: 698 DNELKSSMLKNKEDEKIRSSVEKENQKSK 726
Score = 57.8 bits (138), Expect = 1e-07
Identities = 60/181 (33%), Positives = 77/181 (42%), Gaps = 43/181 (23%)
Query: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------------ 2637
K++ +SSSSSSSSSS S SSS S SSS SS S S++
Sbjct: 188 KKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKK 247
Query: 2638 --SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR---SRSPRKPIDSLRDSRSLS 2692
S S+SS S + PQ+ +P + PP E R +SP K + R +R
Sbjct: 248 RKKSKKSASSESEAENLEAQPQSTVRP--EEIPPIPENRFLMRKSPPKADEKERKNR--- 302
Query: 2693 YSPVERRRPSPQPSPRDQQSSSSER--GSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
ER R P Q +S R +R G++ R P RR TPS R R R
Sbjct: 303 ----ERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGP---RRYRTPSRSRSRDRFRR 355
Query: 2751 S 2751
S
Sbjct: 356 S 356
Score = 55.1 bits (131), Expect = 1e-06
Identities = 48/165 (29%), Positives = 72/165 (43%), Gaps = 12/165 (7%)
Query: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
E P + ++ SSSSSSSSSS S SSS S SSS SS S S++ S K
Sbjct: 176 ELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHR 235
Query: 2657 QALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE----------RRRPSPQPS 2706
+ K KK ++S S ++L + P E R+ P+
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKAD 295
Query: 2707 PRDQQSSSSERGSRRGQRGDSRSPSHKRR-RETPSPRPMRHRSSR 2750
+++++ ER R +S+ S++RR T S R ++ R R
Sbjct: 296 EKERKNRERER-ERECNPPNSQPASYQRRLLVTRSGRKIKGRGPR 339
Score = 54.3 bits (129), Expect = 2e-06
Identities = 80/388 (20%), Positives = 130/388 (33%), Gaps = 48/388 (12%)
Query: 125 AELNEKKNERLRAAFGISDSYVDGS---SFDPQRRAREAKQPAPEPP--KPYSLVRESSS 179
+ELNE K E R+ + + + S P R+ + K+ K + R S
Sbjct: 386 SELNEIK-ENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEK 444
Query: 180 SRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKR- 238
K KK+ K K R + E S + K ++ ++ R S SK R H + K K+
Sbjct: 445 DDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQS 504
Query: 239 --KSKDKKRKRSRS--------------TTPAPKSRRAH-RSTSADSASSSDTSRSRSRS 281
K KD++R RS+ + K RRA RS D + SR+R
Sbjct: 505 DSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRE 564
Query: 282 AAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKD 341
+ + R + + E R S E T S +D+ +
Sbjct: 565 RSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRR 624
Query: 342 KKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTR 401
+++ ++ S R+ + + S + + + N E R
Sbjct: 625 RRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADR 684
Query: 402 DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKN 461
D+SP K+ QSS S K SS E
Sbjct: 685 DQSP---FSKIKQSSQDNELKSSMLKNKEDEKIRSSVEK------------------ENQ 723
Query: 462 RSHGRAKRDKSHSHTPSRRMGRSRSPAT 489
+S G ++ H H +++ SP T
Sbjct: 724 KSKG---QENDHVHEKNKKFDHESSPGT 748
Score = 45.1 bits (105), Expect = 0.001
Identities = 127/640 (19%), Positives = 214/640 (33%), Gaps = 77/640 (12%)
Query: 976 DTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSL 1035
D KP R G + P KVK + S S S + S QS S
Sbjct: 160 DAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDS 219
Query: 1036 CAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPK 1095
+ + + + +S + K + + + SS SE+ +L+++ Q++
Sbjct: 220 ESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS------ESEAENLEAQPQSTV- 272
Query: 1096 GGRSRSSSPVTE---LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNS 1152
R P+ E L +SP + D E + E+ R + +S P
Sbjct: 273 --RPEEIPPIPENRFLMRKSPPKADEKE-------RKNRERERERECNPPNSQPASYQRR 323
Query: 1153 LLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRE 1212
LL T ++ P+ T S R +D+F + +R E
Sbjct: 324 LL-----VTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGE 378
Query: 1213 RSGAGSSPETKE--QNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES 1270
R G E E +N P ++ ++ + SE P + KE + +S
Sbjct: 379 RWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRK-------NEKEKKVKDHKS 431
Query: 1271 SPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSP 1330
+ + + S D+ +++ A S KE S S R++
Sbjct: 432 NSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKS-----------KEKSKSKERDSKHNRN 480
Query: 1331 LEFR-NSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPD 1389
E R S G + E + D G + + E + HS S+
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSK---- 536
Query: 1390 AVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
EK + ++S + SR R S S R SRR RS + RD
Sbjct: 537 --EKDRRAQSRSRECDITKGKHSYNSRTRERSRS---------RDRSRRVRSRTHD--RD 583
Query: 1450 GSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR---SRSPSSPELN 1506
S + H R R RS +P ++ + R R SRS E
Sbjct: 584 RSRSKEYHRYREQEY------RRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQ 637
Query: 1507 NKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSK 1566
++ R + S + + + + +SR +S + S +++++ D SP SK
Sbjct: 638 SRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSS------NNSREKKADRDQSPFSK 691
Query: 1567 AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606
K + + S + D K R S + S + D
Sbjct: 692 IKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQEND 731
Score = 35.8 bits (81), Expect = 0.60
Identities = 62/285 (21%), Positives = 97/285 (34%), Gaps = 45/285 (15%)
Query: 2503 HSDVGEPPASTGAQQPSALAALQPAKER--RSSSSSSSSSSSSSSSSSSSSSSSSSGSSS 2560
H +V E P ++ +KER R +S + + S S S S S
Sbjct: 409 HRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKS 468
Query: 2561 SDSEGSSLPVQPEVALKRVPSP-------TPAPKEAVREGRPPEPTPAKRKRRSSSSSSS 2613
E S + E R S K++ +G+ E + +K K + S S+
Sbjct: 469 KSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSN 528
Query: 2614 SSSSSSSSSSSSSSSSSS------------SSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
S S + S S +S + S S S S ++ K
Sbjct: 529 EHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSK 588
Query: 2662 P----------------ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705
+ ++ PPG RS+ R+ RDSRS S E + +
Sbjct: 589 EYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRR---RRRDSRS---SEREESQSRNKD 642
Query: 2706 SPRDQQSSSSER--GSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748
R+Q+S SS R S +R S+S H + + R +S
Sbjct: 643 KYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQS 687
Score = 34.3 bits (77), Expect = 1.7
Identities = 82/407 (20%), Positives = 139/407 (34%), Gaps = 57/407 (14%)
Query: 871 SCFESSPDPELKSRTPSRHSCSGSSPPRV--KSSTPPRQSPSRSSSPQPKVKAIISPRQR 928
SC E P ++K RH S SS S+ QS S SS + + R++
Sbjct: 173 SCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKK 232
Query: 929 SHSGSSSPSPSRVTSRTTPRRS-RSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQ 987
H +S R ++S S S N+E++ P + V+PE
Sbjct: 233 KHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQ------------PQSTVRPE----- 275
Query: 988 SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSS---TP 1044
I P P+ + P + K +E+ ++ + C S A + T
Sbjct: 276 ----EIPPIPENRFLMRKSPPKADEKERKNRERERE---RECNPPNSQPASYQRRLLVTR 328
Query: 1045 PGESYFGVSSLQLK--GQSQTSPDHRSDTSSPEVRQSHSESPSLQ-SKSQTSPKGGRSRS 1101
G G + + +S++ R + P RQ + ++ S + KG +S
Sbjct: 329 SGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSEL 388
Query: 1102 SSPVTELASRSPIR------QDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLG 1155
+ + RSP+R D S SP K+ + +S+S + NS
Sbjct: 389 NE--IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKE-RDIRRNSEKD 445
Query: 1156 QSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSG 1215
+ + K + + S + K K E + R RS
Sbjct: 446 DKYKNKVKKRAK-----SKSRSKSKEKSKSKERDSKHNRNEEKRM----------RSRSK 490
Query: 1216 AGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKE 1262
KE+ + +D+E EKS++ + H S+ KE
Sbjct: 491 GRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537
Score = 32.0 bits (71), Expect = 8.6
Identities = 42/192 (21%), Positives = 73/192 (38%), Gaps = 20/192 (10%)
Query: 61 ERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGG------KEETPGQ 114
+R RRV R + + ++ Y + QE R E+ PG +
Sbjct: 570 DRSRRVRSRTHDRDRSRSKE-YHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDS 628
Query: 115 RPAVTETHQLAELNEKKNERLRAAFGISDS------YVDGSSFDPQRRAREAKQPAPEPP 168
R + E Q ++ +N+ +++ +S Y + +RE K A
Sbjct: 629 RSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK--ADRDQ 686
Query: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK 228
P+S +++SS K K K+D RS S +E +KS ++ ++KK
Sbjct: 687 SPFSKIKQSSQDNEL--KSSMLKNKEDEKIRS---SVEKENQKSKGQENDHVHEKNKKFD 741
Query: 229 HRSPTPKSKRKS 240
H S + KS
Sbjct: 742 HESSPGTDEDKS 753
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 129 bits (324), Expect = 4e-29
Identities = 300/1547 (19%), Positives = 549/1547 (35%), Gaps = 230/1547 (14%)
Query: 237 KRKSKDK---KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
KRK+++ + K++R + P S + A++ ++ T R A T+++ L
Sbjct: 62 KRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPR------LASTNSSVLGA 115
Query: 294 RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS 353
PS + + A + G T P P T K + S
Sbjct: 116 DLPS---SMKEKAKAETEKAGKTGNSMPH-PATG---------------KTVANLLSGKS 156
Query: 354 PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLP 413
P +S+ EP A T L++E P V+ S + D S
Sbjct: 157 PRKSA---EPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS--------- 204
Query: 414 QSSSSESS---PPSPQPTKVSRHASSSPESPK--PAPAPGSHREISSSPTSKNRSHGRAK 468
SSS E+ PS +P +V + S+ ESP APAPG ++
Sbjct: 205 -SSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDV--------------- 248
Query: 469 RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP 528
TP + G AK+ S + + S +P RS + ++
Sbjct: 249 -------TPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRS-------QVKAS 294
Query: 529 QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588
++ + R+ P ++ T +G + + P G S+T A + S +
Sbjct: 295 EKILQVRAASAP----AKGTPGKGATPA---------PPGKAGAVASQTKAGKPEEDSES 341
Query: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSR 648
+ S S T +++ A+ S+ A SP R+ + +P ++G +
Sbjct: 342 SSEESSDSEEET-PAAKALLQAKASGKTSQVGAASAPAKESP--RKGAAPAPPGKTGPAV 398
Query: 649 SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708
++ A + S++ + S PA+ ++ +PR+G + +
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA---- 454
Query: 709 RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL-SSPRS 767
P++ G + + + + S+ S + S + +++ + + L SP+
Sbjct: 455 --------PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
Query: 768 KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS-----SSSPP 822
K S + + G+ P P K ++ G + ++S + S ++ P
Sbjct: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
Query: 823 PKQKSKTPSRQSHSSSSP--HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
++KS Q+ +SSP P K+G Q P N +S E S D
Sbjct: 567 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES--------SEESSDSA 618
Query: 881 LKSRTPSRHSCSGSSP----PRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS--- 933
P+ + + + P P+ K + P + + + S+ P +PR+ + S
Sbjct: 619 DSEEAPAAMTAAQAKPALKIPQTK-ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 677
Query: 934 SSPSPSRVTSRTTPRRSRSVSPCSNVE-SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992
SSP+ + T R S S S E + L + S +VK + P + G
Sbjct: 678 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 737
Query: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052
P + +T GP+++ K+ EK +DS S +++ P + V
Sbjct: 738 -GTAPVLPGKT--GPTVTQVKA----EKQEDS-----ESSEEESDSEEAAASPAQVKTSV 785
Query: 1053 SSLQLKGQ--SQTSPDHRSDTSSP-----EVRQSHSESPSLQSKSQTSPKGGRSRSSSPV 1105
Q K + +P + S+P Q+ SPS +P+ + P
Sbjct: 786 KKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPA 845
Query: 1106 TELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESK 1165
+ + S + P SG S E+S + ++ + V + Q R A +K
Sbjct: 846 S-VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK 904
Query: 1166 EKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ 1225
E P++ A +PP K P Q ++ +GSS E +
Sbjct: 905 ES----PRKGAAPTPP---GKTGPSAAQ----------------AGKQDDSGSSSEESDS 941
Query: 1226 NSALPTSSQDEELME----VVEKSEEPAG--------QILSHLSSELKEMSTSNFESSPE 1273
+ P + ++++ V+ + PAG Q S ST+ SS
Sbjct: 942 DGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSES 1001
Query: 1274 VEER--PAVSLTLDQSQSQASLEAVEVPSMA--SSWGGPHFSPEHKELSNSPLRENSFGS 1329
+E PA ++ P +A +S G S E +S+ +E
Sbjct: 1002 EDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ 1061
Query: 1330 PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPD 1389
+ P + +T ++ L P L +++ + S SSS D
Sbjct: 1062 VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEED 1121
Query: 1390 AVEKAGMSSNQSISSPVLDAVPRTPSR-ERSSSASSPEMKDGLPRTPSRRSRSG-SSPGL 1447
G S ++ P TPSR E ++ E + PS+ SG +PGL
Sbjct: 1122 GEGPQGAKSAHTLVGP-------TPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGL 1174
Query: 1448 RDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ------TPRPRSRSPS 1501
TP+ S ++P + P S ++ D + +A PQ +P+ + +
Sbjct: 1175 -----TPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAA 1229
Query: 1502 SPELNNKCLTPQRERSGSESS--VDQKTVARTPLGQ----RSRSGSSQELDVKPSASPQE 1555
S K P++ ++S Q + + LGQ + + V QE
Sbjct: 1230 SGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE 1289
Query: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615
R + + ++ R+R SG P + +P K K +
Sbjct: 1290 RKKVVDTTKESSRKGWESRKRKLSGDQP--------------AARTPRSKKKKKLGAGEG 1335
Query: 1616 SGSDSSPEPKAPAPRALPRRSR-SGSSSKGRGPSPEGSSSTESSPEHPPKS--RTARRGS 1672
+ SPE + + +R + SG + +G GS + PE + T G
Sbjct: 1336 GEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGD 1395
Query: 1673 RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
+S+P+ K + + +R+ + E +KA+ + S S S + + +
Sbjct: 1396 QSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKK 1442
Score = 108 bits (269), Expect = 9e-23
Identities = 286/1443 (19%), Positives = 521/1443 (36%), Gaps = 178/1443 (12%)
Query: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR--SESESKKRKHRSPTPKSKRKSKDKK 244
Q KK + D SESS E + + K R S + S + K K K++ +K
Sbjct: 72 QAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
Query: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
++ ++ P P + + ++ + +S +SA +TT + S
Sbjct: 132 AGKTGNSMPHP--------ATGKTVANLLSGKSPRKSAEPSANTTLV--------SETEE 175
Query: 305 EGDAP----FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
EG P ++PG S + S T S + D + K + +P+ S +
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSD-----ETDVEGKPSVKPAQVKASSVST 230
Query: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
E PA A G TP + PP++ R + P + E + S SE
Sbjct: 231 KESPARKAAPAPGKVGD-----VTPQVKGGALPPAK----RAKKPEEESESSEEGSESEE 281
Query: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGS-HREISSSPTSKN---RSHGRAKRDKSHSHT 476
P+ ++V APA G+ + + +P K S +A + + S +
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRR----- 531
S S A + +++ K + S ++ + R G + +P +
Sbjct: 342 SSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP---AKESPRKGAAPAPPGKTGPAV 398
Query: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR 591
++++ +R S+S + + + + + ++P R S PA+ + PA
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS---APAKESPRKGAAPAP 455
Query: 592 RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT 651
R + + + R S R + + + +SP + +
Sbjct: 456 PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG 515
Query: 652 PARRGRSRSRTPARRGRSRSRTPARRSGR----SRSRTPARRGRSRSRTPRR---GRSRS 704
P +G P G+ TP+ + G+ S S + S P + +S
Sbjct: 516 PLGKGAG----PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS 571
Query: 705 RSLVRRGRSHSR----TPQRRGRSG---SSSERKNKSRTSQRRSRSNSSPEMKKSRISSR 757
+ + + S PQ+ G + + + S +S+ S S S E + +++
Sbjct: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 631
Query: 758 RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR-----SRSGSSQPKAKSRTPP 812
+L P++KA + + + + + P + PR+ S +GSS A P
Sbjct: 632 AKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 689
Query: 813 RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK---VKSGTPPRQGSI---TSPQANEQSVT 866
SSS ++ KT + + K VK+ + P +GS+ T+P ++
Sbjct: 690 AEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP 749
Query: 867 PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS---TPPRQSPSRSSSPQPK----- 918
+ E D E S S + +SP +VK+S T + +P+ + +P K
Sbjct: 750 TVTQVKAEKQEDSE-SSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 808
Query: 919 ----VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV-----SPCSNVESRLLPRYSH 969
V A +QRS S P + S R SV + + +++ P
Sbjct: 809 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE-ED 867
Query: 970 SGSSSPDTKVKPET-------PPRQSHSGSISPYP------KVKAQTPPGPSLSGSKSPC 1016
SGSS ++ + E P ++H + P K A TPPG + +
Sbjct: 868 SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 927
Query: 1017 PQEKSKDSLVQS-----CPGSLSLCAGVKSS---TPPGESYFGVSSLQLKGQSQTSP-DH 1067
Q+ S S +S P +++ +K P S G ++ + Q+ ++P
Sbjct: 928 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKA 987
Query: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA--SP 1125
R+ S+ S SE + +Q G R+ + T +P G S+ S
Sbjct: 988 RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS 1047
Query: 1126 MLKSGMSPEQSRFQSDSS--SYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183
+ G E Q DS+ + P S Q++ K K LP + AT +P
Sbjct: 1048 RISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPK--LPEVQQATKAPESS 1105
Query: 1184 KDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELME--V 1241
D +D +SS E G G PT S+ E L+E
Sbjct: 1106 DDS------EDSSDSS---------SGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETA 1150
Query: 1242 VEKSEE----PAGQILS-HLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAV 1296
E SE+ P+ +LS +++ L ++ +++P+++ P+VS TL +
Sbjct: 1151 AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1210
Query: 1297 EVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN 1356
+ P A+ P + +P + P + + T S + + L
Sbjct: 1211 K-PQQAAGMLSPKTGGKEAASGTTPQKSR---KPKKGAGNPQAST---LALQSNITQCLL 1263
Query: 1357 G-PF-LNQLETDPSL-----DMKEQSTRSSGHSSSELSPDAVE--KAGMSSNQ-SISSPV 1406
G P+ LN+ + S+ ++ EQ + ++ E S E K +S +Q + +P
Sbjct: 1264 GQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPR 1323
Query: 1407 LDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGM 1466
+ + E ++ SPE + ++R ++ + G G S S G
Sbjct: 1324 SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKG-------SLGSQGA 1376
Query: 1467 KDIPR---TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSV 1523
KD P G E PK+ + + R + K + SES
Sbjct: 1377 KDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1436
Query: 1524 DQK 1526
+K
Sbjct: 1437 QKK 1439
Score = 104 bits (260), Expect = 1e-21
Identities = 242/1319 (18%), Positives = 459/1319 (34%), Gaps = 205/1319 (15%)
Query: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
G+ TPQ +G G+ K + + S E ++ + RS+ KA
Sbjct: 243 GKVGDVTPQVKG--GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV------KAS 294
Query: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
++ R+ S + K TP ++G+ + K+ P S SSS + +TP
Sbjct: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 831 --------------SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
S+ +S+ + G P T P + + SS
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSS 414
Query: 877 PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP 936
+ + + P++ SG +P +S P ++SP + ++P P PR+ + P
Sbjct: 415 EESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAP-------PRK------TGP 461
Query: 937 SPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996
+ ++V SRS S S+ + L ++ +VKP +
Sbjct: 462 AAAQVQVGKQEEDSRSSSEESDSDREAL-------AAMNAAQVKP-----------LGKS 503
Query: 997 PKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQ 1056
P+VK + G G L AG PPG+ S Q
Sbjct: 504 PQVKPASTMG-----------------------MGPLGKGAG---PVPPGKVGPATPSAQ 537
Query: 1057 L---KGQSQTSPDHRSDTSSPEV------RQSHSESPSLQSKSQTSPKGGRSRSSSPVTE 1107
+ + S++S + SD+S EV Q S LQ+K +SP G + + PV
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
Query: 1108 LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEK 1167
+ A + + S E+S +DS P + + A++K
Sbjct: 598 ------------QVKAEKPMDNSESSEESSDSADSEEAP----------AAMTAAQAKPA 635
Query: 1168 MALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSG--AGSSPETKEQ 1225
+ +P A P + S R + K T P S AG + E
Sbjct: 636 LKIP---QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Query: 1226 NSALPTSSQDEEL--MEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLT 1283
+S+ S +EE + V + G+ L ++ + + ++P + + ++T
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 1284 LDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEM 1343
+++ Q E+ E S + SP ++ S + + +P R GT
Sbjct: 753 QVKAEKQEDSESSEEESDSEEAAA---SP--AQVKTSVKKTQAKANPAAARAPSAKGTIS 807
Query: 1344 NTG------------FSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAV 1391
G S+VK + P + + + + + ++ P+
Sbjct: 808 APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE-- 865
Query: 1392 EKAGMSSNQSISSPVLDAVPRT-PS------RERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
E +G S +S S + + + PS R + A K P P + S +
Sbjct: 866 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 925
Query: 1445 PGLRDGSGTPSRHSLS-GSSPGMKDIPRT---------PSRGRSECDSSPEPKALPQTPR 1494
G +D SG+ S S S G +P + P+R + ++P TPR
Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
Query: 1495 PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQ 1554
S S+ RS S S D+ + P Q G + P+A P+
Sbjct: 986 KARASEST------------ARSSSSESEDEDVI---PATQCLTPGIRTNVVTMPTAHPR 1030
Query: 1555 ERSESDSSPDSKAKTRTPLRQ-RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR-AAP 1612
++ + S +K + + + + G + +VDS P S +S + K + P
Sbjct: 1031 IAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1090
Query: 1613 RAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS 1672
+ ++ P++ S SGS G GP S+ T P +
Sbjct: 1091 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETA 1150
Query: 1673 RSSPEP-------------KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
S E T TP ++S+++P+L +S + +A P+ +
Sbjct: 1151 AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVS-STLAAKDDPDGKQE 1209
Query: 1720 TPPRHRR---SPSVSSPEPAE---KSRSSRRRRSASSPRTKTTSRRGRSPS---PKPRGL 1770
P+ SP E A +S + ++ A +P+ T + + +P L
Sbjct: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
Query: 1771 QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES 1830
++ ++ K T T++ R SR +R+ G +R+P ++
Sbjct: 1270 NEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESR--KRKLSGDQPAARTPRSKKK 1327
Query: 1831 SRTSSRRRRGRS----RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR 1886
+ + S +T TS+ +++ + K + + S + + +
Sbjct: 1328 KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKG 1387
Query: 1887 RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR------SRTPPVTRRRSRSRT 1939
S +S+ + +R + + +++++ S +P +++ + +T
Sbjct: 1388 MGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1446
Score = 103 bits (256), Expect = 3e-21
Identities = 255/1354 (18%), Positives = 451/1354 (33%), Gaps = 223/1354 (16%)
Query: 892 SGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS------RVTSRT 945
+ + PR+ S+ SS + K KA + +G+S P P+ + S
Sbjct: 98 TAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMPHPATGKTVANLLSGK 155
Query: 946 TPRRSRSVSPCSNVESRL-----LPRY--------------------SHSGSSSPDTKVK 980
+PR+S S + + S +P + + S S D + K
Sbjct: 156 SPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGK 215
Query: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSP--------------CPQEKSKDSLV 1026
P P Q + S+S + P P G +P P+E+S+ S
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS-E 274
Query: 1027 QSCPGSLSLCAGVKSSTPPGESYFGV--SSLQLKG-----------------QSQT---S 1064
+ AG +S E V +S KG SQT
Sbjct: 275 EGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGK 334
Query: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
P+ S++SS E S E+P+ ++ Q +++S +++ + S ++ A+
Sbjct: 335 PEEDSESSSEESSDSEEETPAAKALLQ-------AKASGKTSQVGAASAPAKESPRKGAA 387
Query: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK 1184
P P ++ Q+ + QS E ++S+E+ P Q + P+ +
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDS--------QSSSEESDSEEE--APAQAKPSGKAPQVR 437
Query: 1185 DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ----NSALPTSSQDEELME 1240
+P R K PPR+ A + + +Q S+ S D E +
Sbjct: 438 AASAPAKESPR-------KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
Query: 1241 VVEKSE-EPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299
+ ++ +P G+ S ++K ST + P + + A + E
Sbjct: 491 AMNAAQVKPLGK-----SPQVKPASTMGMGPLGK-GAGPVPPGKVGPATPSAQVGKWEED 544
Query: 1300 SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
S +SS S + +P +E S G+ L+ + T ++ GP
Sbjct: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK---------PTSSPAKGPPQKAGPV 595
Query: 1360 LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS 1419
Q++ + +D E S SS + SE +P A+ A + ++ P A P+ + S
Sbjct: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA--QAKPALKIPQTKACPKKTNTTAS 653
Query: 1420 SSASSPEMKDGLPR-TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD--------IP 1470
+ + + PR + S +GSSP + G+ P+ S S ++ +
Sbjct: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
Query: 1471 RTPSRGRS---ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527
+ S G+ + S P +L Q P + P + Q + SE D +
Sbjct: 714 QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEE 773
Query: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
A +P ++ +Q +A + S+P +QRS S P V +
Sbjct: 774 AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN 833
Query: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSG-----------SDSSPEPKAPA---PRALP 1633
+ S P V A +AQ+G SDS E + A P
Sbjct: 834 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKT 893
Query: 1634 RRSRSG------SSSKGRGPSP----------------EGSSSTESSPEHPPKSRTARRG 1671
+ R+ S KG P+P GSSS ES + +
Sbjct: 894 HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Query: 1672 SRSSP----EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS--------PETRSR 1719
P +P P + + RKAR S + +SSS P T+
Sbjct: 954 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL 1013
Query: 1720 T----------PPRHRRSPSVSSPEPAEKSRSSRR---RRSASSPRTKTTSRRGRSPSPK 1766
T P H R +S A S+ S R + P T+ S G P+
Sbjct: 1014 TPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATS 1073
Query: 1767 P-------RGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819
P +G + R E + T+ + S S+ +S S + +
Sbjct: 1074 PQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT 1133
Query: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSR 1879
+P+R E+ + S+ +P +PA + S++
Sbjct: 1134 LVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG--------LTPANSQASKA- 1184
Query: 1880 TPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRT 1939
TP + S S T + + ++ + + + + S T P R+ +
Sbjct: 1185 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGA 1244
Query: 1940 PTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999
+ + + +T+ P + S +T + R V + SR
Sbjct: 1245 GNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKG 1304
Query: 2000 PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059
+R+R S P +RTP +K+ S +T
Sbjct: 1305 WESRKRKLSGDQPA------------------ARTPRSKKKKKLGAGEGGEASVSPEKTS 1346
Query: 2060 RTARGKRSLTRSPPAIRRRSASGSSSDRSRSATP 2093
T++GK ++ ++ + GS + P
Sbjct: 1347 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1380
Score = 99.4 bits (246), Expect = 4e-20
Identities = 261/1315 (19%), Positives = 477/1315 (36%), Gaps = 183/1315 (13%)
Query: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKK----DRGRRSESSSP---RRERKKS 212
A++ AP P K + + P K+ KK +++ + G SE +P R + K S
Sbjct: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
Query: 213 SKKKKHRSESESKKR---KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
K + R+ S K K +P P K + S T A K S+S +S+
Sbjct: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAV-------ASQTKAGKPEEDSESSSEESS 347
Query: 270 SSSD-TSRSRSRSAAAKTHTTALAGRSPSPA--SGRRGEGDAP---------FSEPGTTS 317
S + T +++ A + T+ G + +PA S R+G AP ++ G
Sbjct: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
Query: 318 TQRPSSPETATKQPSSPYEDKDKDK--KEKSATRPSPSPERSSTGPEPPAPT-PLLAERH 374
SS E + + +P + K K + ++A+ P+ R P PP T P A+
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPP--KSPEKLPQSSS-----SESSPPSPQP 427
G + + + + + + A+ + P KSP+ P S+ + + P P P
Sbjct: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP-P 526
Query: 428 TKVSRHASSSPESPKPAPAPGSHREISSS-----PT----SKNRSHGRAKRDKSHSHTPS 478
KV S+ + S E S S PT ++ +S G + K S +P+
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-SPA 585
Query: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
+ + P + ++ P S S S A + Q + + PQ
Sbjct: 586 KGPPQKAGPVAV---QVKAEKPMDNSESSEESSDSADSEEAP--AAMTAAQAKPALKIPQ 640
Query: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
+ NT + R G R T +PA G ++ PA S S
Sbjct: 641 TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG--GTQRPAEDSSSSEE 698
Query: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR-RRSRSRSPARRSGRSRSRTPARRGR 657
++ G+++S + PV+ + +P P + G
Sbjct: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV---------LPGKTGP 749
Query: 658 SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
+ ++ A + + + +PA+ S +T + + +R
Sbjct: 750 TVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA----------ARA 799
Query: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
P +G + + + +++RS S P ++ + S+ +R +S S
Sbjct: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS---------- 849
Query: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
G + ++QT P SGSS+ ++ S + + + P K+ +
Sbjct: 850 --VGKAVATAAQAQTGPEED-SGSSEEESDSE---EEAETLAQVKPSGKTHQIRAALAPA 903
Query: 838 SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897
K + TPP + ++ QA +Q SGSS
Sbjct: 904 KESPRKGAAPTPPGKTGPSAAQAGKQ--------------------------DDSGSSS- 936
Query: 898 RVKSSTPPRQSPSRSSSPQP-KVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPC 956
+ S ++P+ +S Q K I RS +G ++ +P++ + +TPR++R+
Sbjct: 937 --EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA-TPAQAQAASTPRKARASEST 993
Query: 957 SNVESRLLPRYSHSGSSSPDTKVKPETP-PRQSHSGSISPYPKVKAQTPPGPSLSGSKSP 1015
+ S S S D V P T ++ P + P S++G+ S
Sbjct: 994 AR----------SSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSS 1043
Query: 1016 CPQEKSKDSLVQSCPGS-LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS----PDHRSD 1070
+ D Q P + + G +T P +S+Q KG ++ P+ +
Sbjct: 1044 KESSRISDGKKQEGPATQVDSAVGTLPATSPQS-----TSVQAKGTNKLRKPKLPEVQQA 1098
Query: 1071 TSSPEVRQSHSESPSLQSKSQ---TSPKGGR----------SRSSSPVTELASRSPIRQD 1117
T +PE +S S S+ P+G + SR+ + V E A+ S +D
Sbjct: 1099 TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAES--SED 1156
Query: 1118 RGEFSASPMLKSGMSPEQSRFQSDSS-SYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176
+ +L M+P + S +S + P +DS+ + + + K PQ+ A
Sbjct: 1157 DVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAA 1216
Query: 1177 TASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDE 1236
P+ K + P+ S R P + +S + N Q
Sbjct: 1217 GMLSPKTGGKEAASGT--TPQKS-------RKPKKGAGNPQASTLALQSNITQCLLGQPW 1267
Query: 1237 ELMEVVEKSEEPAGQILSH-LSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEA 1295
L E + + ++L+ L E K++ + ESS + E L+ DQ ++
Sbjct: 1268 PLNEA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1325
Query: 1296 VEVPSMASSWGGPHFSPEHKELSN--SPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKE 1353
+ A G SPE ++ R+ + G E + G LG++ G E +E
Sbjct: 1326 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---GAKDEPEE 1382
Query: 1354 DLN---GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP 1405
+L G +++P K++ +S + + +KA +S + SP
Sbjct: 1383 ELQKGMGTVEGGDQSNPK--SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP 1435
Score = 94.7 bits (234), Expect = 1e-18
Identities = 265/1434 (18%), Positives = 488/1434 (34%), Gaps = 199/1434 (13%)
Query: 1343 MNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS--ELSPDAVEKAGMSSNQ 1400
++T SSE +E+ + P L S + SS E + EKAG + N
Sbjct: 82 ISTSESSEEEEEAEA---ETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGN- 137
Query: 1401 SISSPVLDAVP------RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
S+ P ++P + SA++ + + + + PG+
Sbjct: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
Query: 1455 SRHSLSGSSPGMKDIPRTPS----RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCL 1510
S + SS D+ PS + ++ S+ E A P P +P++ L
Sbjct: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGAL 257
Query: 1511 TPQR-----ERSGSESSVDQKTVARTPLGQRSRSGSSQE-LDVKPSASPQERSESDSSPD 1564
P + E S ++ P G RS+ +S++ L V+ +++P + + +
Sbjct: 258 PPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
Query: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
+ + ++++G PE DS+S S S E +A +A++ +S
Sbjct: 318 APPGKAGAVASQTKAGK-PEEDSESS----SEESSDSEEETPAAKALLQAKASGKTSQVG 372
Query: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR------SSPEP 1678
A AP S KG P+P G + P A+ G R SS E
Sbjct: 373 AASAPA-------KESPRKGAAPAPPGKTG--------PAVAKAQAGKREEDSQSSSEES 417
Query: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR-------HRRSPSVS 1731
++ P + + S +P++ + ++ S ++P +T P + S S
Sbjct: 418 DSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS 477
Query: 1732 SPEPAEKSRSSRRRRSAS-------SPRTKTTSRRGRSP-----SPKPRGLQRSRSRSRR 1779
S E ++ R + +A+ SP+ K S G P P P G + S +
Sbjct: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 1780 -------EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR 1832
++ + D S T+ + +S + + + + SPA+ +
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKP------TSSPAKGPPQK 591
Query: 1833 TSSRRRRGRSRTPPTSRKRSRSRTSPA-----PWKRSRSRASPATHRRSRSRTPLISRRR 1887
+ ++ P + + S + A P + ++A PA P +
Sbjct: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT 651
Query: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947
+ ++ +PV R T R+ + + S T S S +
Sbjct: 652 ASAKVAPV-----RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 1948 SRTPPVTRRRS-------RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
V + +S ++ + PV + + + + T ++ S +S
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 2001 VTRRRSRSRTSPVTRRRSRSRT-----PPAIRRRSRSRTPLLPRK------RSRSRSPLA 2049
+ SP + S +T P A R S T P K +++ RSP
Sbjct: 767 EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSK 826
Query: 2050 IRRRSRSRTPRT--ARGKRSLTRSPPAIRRRSA--------SGSSSDRSRSATPPAT--R 2097
++ R+ T ARG S+ A+ + SGSS + S S T +
Sbjct: 827 VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Query: 2098 NHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMM 2157
+T + + R +PTP PG P + QAG
Sbjct: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTP------PGKTGPSAA---------QAGKQ-- 929
Query: 2158 DGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP-----PSMSAAGLAARMSQVP 2212
D +S E+ + A+T+ + +PP P+ S AG AA +Q
Sbjct: 930 --------DDSGSSSEESDSDGEAPAAVTSAQV--IKPPLIFVDPNRSPAGPAATPAQAQ 979
Query: 2213 APVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLAS 2272
A R + + +S + + TP I T V + P A ++A
Sbjct: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
Query: 2273 PRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALA-ALSLTGSGTPPT----------AA 2321
++ S ++ + A V+ A PA + S+ GT A
Sbjct: 1040 ASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQAT 1099
Query: 2322 NYPSSS-----------------RTPQAPASAN-LVGPRSAHATAPVNIAGSRTAA--AL 2361
P SS PQ SA+ LVGP + V + ++ +
Sbjct: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1159
Query: 2362 APA-SLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMT 2420
AP+ SL S M P L+ AN + + S ++ D + + M
Sbjct: 1160 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1219
Query: 2421 SERAPSPSSRMGQAPSQSLLPP-AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA 2479
S + + G P +S P P++ + S+ ++CL+ Q P+ +Q +S
Sbjct: 1220 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1279
Query: 2480 VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSS 2539
T + ++ +G QP+A K++ + +
Sbjct: 1280 KVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG-DQPAARTPRSKKKKKLGAGEGGEA 1338
Query: 2540 SSSSSSSSSSSSSSSSSGSSSSD-----------SEGSSLPVQPEVALKRVPSPTPAPKE 2588
S S +S++S + +S D S+G+ +PE L++ +
Sbjct: 1339 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK--DEPEEELQKGMGTVEGGDQ 1396
Query: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
+ + + + KRK+ + +S+ S S S ++ +
Sbjct: 1397 SNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
Score = 92.8 bits (229), Expect = 4e-18
Identities = 264/1461 (18%), Positives = 502/1461 (34%), Gaps = 186/1461 (12%)
Query: 1364 ETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSAS 1423
E D +L K+ TR S S+ S + E+A + A PR S S +
Sbjct: 66 EEDAALQAKK--TRVSDPISTSESSEEEEEA--------EAETAKATPRLASTNSSVLGA 115
Query: 1424 S--PEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECD 1481
MK+ + ++G+S +G + LSG SP P + SE +
Sbjct: 116 DLPSSMKEKAKAETEKAGKTGNSMP-HPATGKTVANLLSGKSPRKSAEPSANTTLVSETE 174
Query: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541
A +P S + +++ S E+ V+ K + P ++ S S
Sbjct: 175 EEGSVPAFGAAAKPGMVSAGQADSSSE----DTSSSSDETDVEGKPSVK-PAQVKASSVS 229
Query: 1542 SQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSS 1601
++E + A+P D +P K P ++ + E + S + +G+
Sbjct: 230 TKESPAR-KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
Query: 1602 PEVKDKPR--------AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
+VK + A + G ++P P A + S E S
Sbjct: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
Query: 1654 STESSP------EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
S E +P + +T++ G+ S+P ++ + ++ P + + R
Sbjct: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE 408
Query: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767
S SSS E+ S + PS +P+ R+AS+P K + R+G +P+P
Sbjct: 409 DSQSSSEESDSEEEAPAQAKPSGKAPQV----------RAASAP-AKESPRKGAAPAPPR 457
Query: 1768 R----------GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG- 1816
+ G Q SRS E++ + R + ++ + ++ + +S G
Sbjct: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDRE---ALAAMNAAQVKPLGKSPQVKPASTMGM 514
Query: 1817 ---GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATH 1873
G G P + + S++ + + +S + S S P + +PA
Sbjct: 515 GPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVP-----TAVAPA-Q 568
Query: 1874 RRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933
+S S ++ P + + S +S S + S P
Sbjct: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 628
Query: 1934 RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV-----TRRRSRSRTSPI---------TR 1979
++++ P + P T + ++ PV R++ + TSP T+
Sbjct: 629 AAQAK-PALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQ 687
Query: 1980 RRSRSRTSPVTRRRSRSRTS-PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLP 2038
R + +S +T VT +++S + + ++ + P + P+LP
Sbjct: 688 RPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL---QVKAASVPVKGSLGQGTAPVLP 744
Query: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
K + + + ++ S + SP ++ S A P A R
Sbjct: 745 GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT-----SVKKTQAKANPAAARA 799
Query: 2099 HSGSRT---PPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGS 2155
S T P + ++ + PS P+ ++ +L +S +
Sbjct: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 859
Query: 2156 MMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV 2215
GP + S E A++ LA S T + +++ A + R P P
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAET---LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
Query: 2216 PLMSLRTAP-AANLASRIPAASAAAMNLASARTPAIPTAVNLAD--------SRTPAAAA 2266
+T P AA + + S++ + + PA T+ + +R+PA A
Sbjct: 917 G----KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
Query: 2267 AMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSS 2326
A +P A A S A TA + + A LT G P++
Sbjct: 973 A----TPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLT-PGIRTNVVTMPTA 1027
Query: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
P+ A++ G S+ ++ ++ + A ++ A+ TSP+
Sbjct: 1028 H--PRIAPKASMAGASSSKESSRISDGKKQEGPA--------TQVDSAVGTLPATSPQ-S 1076
Query: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP-----SQSLLP 2441
S + + + P L + T S S + S S G+ P + +L+
Sbjct: 1077 TSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVG 1136
Query: 2442 PAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGV 2501
P + + V ++ S + VA SQSL SG + + A S +
Sbjct: 1137 PTPSRTETLVEETAAESS-----EDDVVAPSQSLLSGYMTPGLTPAN------SQASKAT 1185
Query: 2502 PHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
P D +ST A + + ++ + S + ++S ++ S +
Sbjct: 1186 PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAG 1245
Query: 2562 DSEGSSLPVQPEVALKRVPSPTP---------------------------APKEAVREG- 2593
+ + S+L +Q + + P P KE+ R+G
Sbjct: 1246 NPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGW 1305
Query: 2594 ----------RPPEPTP--AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
+P TP K+K+ + +S S +S++S + +S
Sbjct: 1306 ESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEK 1365
Query: 2642 SSSSSSSPSPAKPGP-QALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR 2700
S AK P + L K + G +S K D R E+++
Sbjct: 1366 KGKGSLGSQGAKDEPEEELQKGMGTVE---GGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1422
Query: 2701 PSPQPSPRDQQSSSSERGSRR 2721
+ + S +D +S S ++ ++
Sbjct: 1423 KAKKASTKDSESPSQKKKKKK 1443
Score = 90.9 bits (224), Expect = 2e-17
Identities = 247/1303 (18%), Positives = 460/1303 (35%), Gaps = 189/1303 (14%)
Query: 1514 RERSGSESSVDQ--KTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSS------PDS 1565
R+R E + Q KT P+ S +E + + + + + ++SS P S
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 1566 -KAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
K K + + ++G+S + + + SG SP + A P A + S E
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGK-TVANLLSGKSP----RKSAEPSANTTLVSETEE 175
Query: 1625 KAPAPRALPRRSRSGSSSKGRGPSPE---GSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681
+ P A ++ G S G+ S SSS E+ E P + A+ + S ++
Sbjct: 176 EGSVP-AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESP 234
Query: 1682 SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS 1741
+R +++P + ++ + + + P R++ P S S E
Sbjct: 235 AR--------KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
Query: 1742 SRRR----------RSASSPRTKTTSRRGRSPSPKPR-GLQRSRSRSRR-EKTRTTRRRD 1789
+R + R+AS+P K T +G +P+P + G S++++ + E+ + +
Sbjct: 287 TRSQVKASEKILQVRAASAP-AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE 345
Query: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ--------ESSRTSSRRRRGR 1841
S S + T + ++++ + G + ++ R+ ++ ++ + G+
Sbjct: 346 SSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK 405
Query: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSR 1901
S AP + S +P R+ S S R+ + P +
Sbjct: 406 REEDSQSSSEESDSEEEAPAQAKPSGKAPQV--RAASAPAKESPRKGAAPAPPRKTGPAA 463
Query: 1902 SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR--SRTPTTRRRSRSRTPPVTRRRSR 1959
++ V ++ SR+S R + + + ++P + S P+ +
Sbjct: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGK--GA 521
Query: 1960 SRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2019
PP + P T ++ V + S +S S P ++
Sbjct: 522 GPVPP-------GKVGPATP------SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 568
Query: 2020 SRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSR-----SRTPRTARGKRSLTRSPPA 2074
++ I + + +P + + P+A++ ++ S + + +P A
Sbjct: 569 EKSLGNILQAKPTSSPA--KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 626
Query: 2075 IRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPG 2134
+ A + A P T + ++ PV + + +P SP
Sbjct: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQ----------APRKAGTATSP- 675
Query: 2135 MLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS-RIALALTAISLGTA 2193
AG S G + P +S E+ ++ + LA+T +
Sbjct: 676 -----------------AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSV 718
Query: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANL--ASRIPAASAAAMNLASARTPAIP 2251
+ AA + + S P++ +T P A + + ++ S A P
Sbjct: 719 GKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSL 2311
V + +T A A +P A APSA T +AP G AA A
Sbjct: 779 AQVKTSVKKTQAKA------NPAAARAPSAKG-----TISAP-----GKVVTAAAQAKQR 822
Query: 2312 TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA----TAPVNIAGSRTAAALAPASL- 2366
+ S P N +S+ + PAS VG A A T P +GS + +
Sbjct: 823 SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAE 882
Query: 2367 TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426
T A++ P+ + + P R +PP +T PSA + + S
Sbjct: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP------GKTGPSAAQAGKQDDSGSSS 936
Query: 2427 PSSRM-GQAPS-----QSLLPPA--QDQPRSPV-PSAFSDQSRCLIAQTTPVAGSQSLSS 2477
S G+AP+ Q + PP D RSP P+A Q++ A +TP S S+
Sbjct: 937 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ---AASTPRKARASEST 993
Query: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537
+++ S D PG+ + V P+A + P
Sbjct: 994 ARSSSSESEDEDVIPATQCLTPGIRTNVV---------TMPTAHPRIAP----------- 1033
Query: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597
+S + +SSS SS S EG + V V SP +A + +
Sbjct: 1034 ----KASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRK 1089
Query: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------------SSS 2642
P + ++ + + SS S SS SSS S + S+ +
Sbjct: 1090 PKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEET 1149
Query: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPS 2702
++ SS P L +P P + S++ K L S S+S + + P
Sbjct: 1150 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPK----LDSSPSVSSTLAAKDDPD 1205
Query: 2703 PQPSPRDQQSS---SSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
+ + QQ++ S + G + G + S K ++ +P+
Sbjct: 1206 GKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQ 1248
Score = 71.6 bits (174), Expect = 1e-11
Identities = 121/513 (23%), Positives = 191/513 (37%), Gaps = 66/513 (12%)
Query: 2214 PVPLMSLRT--APAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271
PV L+ + T + L + A AA+ R + P + + + A A A
Sbjct: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRV-SDPISTSESSEEEEEAEAETAKA 101
Query: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSS---R 2328
+PR A S+V AD P++ A S+ T T AN S +
Sbjct: 102 TPRLASTNSSVLGAD--LPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRK 159
Query: 2329 TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLS 2388
+ + A+ LV + P A A + SA A + S +S S
Sbjct: 160 SAEPSANTTLVSETEEEGSVPA-------FGAAAKPGMVSAGQADSSSEDTSSS-----S 207
Query: 2389 AYERVSGRTS-PPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ---SLLPPAQ 2444
V G+ S P +A S + +P++ + AP+P ++G Q LPPA+
Sbjct: 208 DETDVEGKPSVKPAQVKASSVSTKESPAR-----KAAPAPG-KVGDVTPQVKGGALPPAK 261
Query: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
R+ P S+ S GS+S A A T S +L V A P
Sbjct: 262 ---RAKKPEEESESSE---------EGSES-EEEAPAGTRSQVKASEKILQVRAASAPAK 308
Query: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
G P P A+ + S SSS SS S + ++ + + S
Sbjct: 309 --GTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 366
Query: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
+S +V + + KE+ R+G P P P K + + + S SSS
Sbjct: 367 KTS----------QVGAASAPAKESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSE 415
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG---------ERRS 2675
S S + + + S + ++ +PAK P+ PA P+K P E S
Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
Query: 2676 RSPRKPIDSLRDS-RSLSYSPVERRRPSPQPSP 2707
RS + DS R++ +++ + V+ SPQ P
Sbjct: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Score = 70.1 bits (170), Expect = 3e-11
Identities = 104/464 (22%), Positives = 164/464 (35%), Gaps = 44/464 (9%)
Query: 2264 AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
AA + S + V L D T L R AAL + +
Sbjct: 26 AAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTS 85
Query: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
SS +A A PR A + V A P+S+ A A T
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSV-------LGADLPSSMKEKAKAET-EKAGKTGN 137
Query: 2384 RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS-SRMGQAPSQSLLPP 2442
+P A +G+T LL R + + + SE S G A ++
Sbjct: 138 SMPHPA----TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSA 193
Query: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Q S S+ SD+ T V G S+ V ++ S + + PAPG
Sbjct: 194 GQADSSSEDTSSSSDE--------TDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG-- 243
Query: 2503 HSDVGE-PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
VG+ P G P A A +P +E S SS S S + + + S +
Sbjct: 244 --KVGDVTPQVKGGALPPAKRAKKPEEE---SESSEEGSESEEEAPAGTRSQVKASEKIL 298
Query: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621
+S P + P+P P AV A + + S SSS SS
Sbjct: 299 QVRAASAPAKGTPGKGATPAP-PGKAGAV----------ASQTKAGKPEEDSESSSEESS 347
Query: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
S + ++ + + +S +S ++ +PAK P+ PA P K P ++++ ++
Sbjct: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
Query: 2682 ID---SLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG 2722
D S +S S +P + + P R S+ ++ R+G
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVR-AASAPAKESPRKG 450
Score = 64.7 bits (156), Expect = 1e-09
Identities = 156/764 (20%), Positives = 250/764 (32%), Gaps = 119/764 (15%)
Query: 2072 PPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTP----- 2126
P + A SS D S S+ + P + +S +S P+ P
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEGKPSVK--PAQVKASSVSTKESPARKAAPAPGKV 245
Query: 2127 --LDRCRSPGMLEPLGSSRTPMSVLQQAG-GSMMDGPGPRIPDHQRTSVPENHAQSRIAL 2183
+ G L P ++ P + + GS + P + E Q R A
Sbjct: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPA-GTRSQVKASEKILQVRAAS 304
Query: 2184 ALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLA 2243
A + G P AG A ++ P + +++ PAA A A
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
Query: 2244 SARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGA--- 2300
S +T + AA+A SPR AP+ P T PAV A A
Sbjct: 365 SGKTSQV------------GAASAPAKESPRKGAAPA------PPGKTGPAVAKAQAGKR 406
Query: 2301 ------------RTPAALAALSLTGSGTPPTAANYPS--SSRTPQAPASANLVGPRSAHA 2346
A A +G AA+ P+ S R APA GP +A
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
Query: 2347 TAPVNIAGSRTAA--------ALAPASLTSAR---------------MAPALSGANLT-- 2381
SR+++ ALA + + M P GA
Sbjct: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 2382 ------SPRVPLSAYERVSGRTSPPLLDRARSRTPPS-APSQSRM---------TSERAP 2425
+P + +E S +S D + P + AP+Q + TS A
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK 586
Query: 2426 SPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV----- 2480
P + G Q D S S+ S S A T +L
Sbjct: 587 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646
Query: 2481 -ATTTSSAGDHNGMLSVPAP---GVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536
TT+SA + AP G S G PA G Q +PA++ SSSS
Sbjct: 647 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQ-------RPAED--SSSSE 697
Query: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPP 2596
S S + + + + S + +S+PV+ + AP + G
Sbjct: 698 ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSL------GQGTAPVLPGKTGPTV 751
Query: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG- 2655
A+++ S SS S S +++S + +S + + ++ +++ + S+ + + PG
Sbjct: 752 TQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGK 811
Query: 2656 ---PQALPKPASPKKPPPGERRSRS----PRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708
A K SP K P R ++ R P ++++ + + P
Sbjct: 812 VVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSS 871
Query: 2709 DQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
+++S S E Q S R P+ R ++ +P
Sbjct: 872 EEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
Score = 60.8 bits (146), Expect = 2e-08
Identities = 131/705 (18%), Positives = 234/705 (33%), Gaps = 97/705 (13%)
Query: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK 216
A +AKQ +P KP ++S+ + P K + P E S ++
Sbjct: 816 AAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP--EEDSGSSEE 873
Query: 217 KHRSESESKKRKHRSPTPKSKR------KSKDKKRKRSRSTTPAPKSRRAHRSTSAD-SA 269
+ SE E++ P+ K+ + +K+ RK + T P A ++ D S
Sbjct: 874 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG 933
Query: 270 SSSDTSRSRSRSAAAKTHTTALAGRSP----SPASGRRGEGDAPFSEPGTTSTQRPSSPE 325
SSS+ S S + AA T + + P P G P ++ ++ + E
Sbjct: 934 SSSEESDSDGEAPAAVTSAQVI--KPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASE 991
Query: 326 TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTP 385
+ + SS ED+D + T P + P P +A +
Sbjct: 992 STARSSSSESEDEDVIPATQCLT-----PGIRTNVVTMPTAHPRIAPK------------ 1034
Query: 386 LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPK--- 442
S + E+S D + P S+ SPQ T V ++ PK
Sbjct: 1035 ASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPE 1094
Query: 443 -----PAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT-----PSRRMGRSRSPATAKR 492
AP E SS +S + G + +HT PSR A A+
Sbjct: 1095 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETA-AES 1153
Query: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR---SPQRRGRSRSPQRPGWSRSRNTQ 549
P++ S +P + S + SP + P + Q
Sbjct: 1154 SEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQ 1213
Query: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTP 609
+ S + G + S T +SR P + + T + T
Sbjct: 1214 QAAGMLSPKTGGKEAASGTTP-------------QKSRKPKKGAGNPQASTLALQSNITQ 1260
Query: 610 ARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS 669
G+ P S V+ + R+ ++ +R+G + +
Sbjct: 1261 CLLGQP---WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQP 1317
Query: 670 RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSE 729
+RTP + + + A G S +P + + S+ +R ++ SG E
Sbjct: 1318 AARTPR---SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKA----------SGDVKE 1364
Query: 730 RKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK 789
+K K + ++ E++K + + S+P+SK K+K
Sbjct: 1365 KKGKGSLGSQGAKDEPEEELQKG-MGTVEGGDQSNPKSK------------------KEK 1405
Query: 790 SQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
++ R+ + K K++ + S S K+K K + Q+
Sbjct: 1406 KKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
Score = 52.0 bits (123), Expect = 8e-06
Identities = 62/279 (22%), Positives = 114/279 (40%), Gaps = 45/279 (16%)
Query: 111 TPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
TPG PA ++ K +L ++ +S + + DP + Q A P
Sbjct: 1171 TPGLTPANSQA-------SKATPKLDSSPSVSSTLA--AKDDPDGKQEAKPQQAAGMLSP 1221
Query: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSS---------------PRRERKKSSKK 215
+ +E++S +P QK +K KK G S+ P E + +
Sbjct: 1222 KTGGKEAASGTTP---QKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASV 1278
Query: 216 KKHRSES-ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA---PKSRRAHRSTSADSASS 271
K +E E +++K T +S RK + ++++ PA P+S++ + + + +
Sbjct: 1279 VKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEA 1338
Query: 272 SDTSRSRSRSAAAKTHTTALAG----RSPSPASGRRGEGDAPFSE----PGTTSTQRPSS 323
S + S ++ K +G + + G +G D P E GT S+
Sbjct: 1339 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSN 1398
Query: 324 PETATKQPSSPYEDKDKDKKE------KSATRPSPSPER 356
P++ ++ S KDK+KKE K++T+ S SP +
Sbjct: 1399 PKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1437
Score = 42.4 bits (98), Expect = 0.006
Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 7/144 (4%)
Query: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV-DGSSFDPQRRAREAKQPAPE 166
K + G +PA KK ++L A G S + +S + +A+ K
Sbjct: 1309 KRKLSGDQPAARTPRS------KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV 1362
Query: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
K S ++ ++ +K G + ++E+KKS K+KK + + E KK
Sbjct: 1363 KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1422
Query: 227 RKHRSPTPKSKRKSKDKKRKRSRS 250
+ ++ T S+ S+ KK+K+ ++
Sbjct: 1423 KAKKASTKDSESPSQKKKKKKKKT 1446
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 127 bits (318), Expect = 2e-28
Identities = 358/1532 (23%), Positives = 535/1532 (34%), Gaps = 218/1532 (14%)
Query: 247 RSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG 306
RS TT P S TS+ + S TS SR S THTTA G + P G E
Sbjct: 131 RSPDTTHLPASM-----TSSGVSEESTTSHSRPGS----THTTAFPGSTTMP--GLSQES 179
Query: 307 DAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP-PA 365
A S PG T T T P S T S PE ++ P
Sbjct: 180 TASHSSPGPTDT---------TLSPG-------------STTASSLGPEYTTFHSRPGST 217
Query: 366 PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
T LL + S A+ P+ S SP SP S + +S++ S P S
Sbjct: 218 ETTLLPDNTTASGLLEASMPVHS------STRSPHTTLSPAGSTTRQGESTTFHSWPSS- 270
Query: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPT----SKNRSHGRAKRDKSHSHTP--SR 479
K +R A + S P+ SH SS PT +++ + G + ++ +P ++
Sbjct: 271 ---KDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 327
Query: 480 RMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQR 539
M S T+ RG + + + H+ S +P + + SP + P
Sbjct: 328 TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD- 386
Query: 540 PGWSRSRNTQRRGRSRSARRGRSHSRSPATRG---RSRSRTPARRGRSRSRTPARRRSRS 596
S T R +A SHS AT +RS T G S T + S S
Sbjct: 387 -----SSTTSGRSEESTA----SHSSQDATGTIVLPARSTTSVLLGES---TTSPISSGS 434
Query: 597 RTPTRRRSRSRTPARRGRSRS-RTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR 655
T + TP RS + + R + T SP + S + S SRSR +
Sbjct: 435 METTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA--STTSSGVSEESTTSRSRPGSTH 492
Query: 656 GRSRSRTPARRGRSRSRTPARRSGRSRSRT--PARRGRS-RSRTPRRGRSRSRSLVRRGR 712
+ + G SR T + S S T PA S S+ S S S
Sbjct: 493 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALS 552
Query: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
S T G+ ++ S + S +S + ++ S+R S SPR+
Sbjct: 553 PGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA--STRVHSSTGSPRTTLSPA 610
Query: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
S L G S QT P + + S P + + SP + P+
Sbjct: 611 SSTSPGLQGESTA----FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 666
Query: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFES-SPDPELKSRTPSRHSC 891
+ S S + +P G T+P + + + + S SP + P +
Sbjct: 667 STTSGHSEKSTIFHSSPDASG--TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 724
Query: 892 SGSSPPRVKSSTPPRQSPSRSSSPQPKVKAII---SPRQRSHSGS--SSPSPSRVTSRTT 946
G S + PR SP+ + SP + S RS GS S+ SP+ T+
Sbjct: 725 PGLSEASTTFYSSPR-SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 783
Query: 947 PRRSRSV--SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP 1004
S +V S + E+ + P S T V E P HS S + + +
Sbjct: 784 SEESTTVYSSSRGSTETTVFPH-------STTTSVHGE-EPTTFHSRPASTHTTLFTEDS 835
Query: 1005 PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLC-AGVKSSTPPGESYFGVSSLQLKGQSQT 1063
L+ + P S S P +L+ G +S+T P S G + +L T
Sbjct: 836 TTSGLTEESTAFP--GSPASTQTGLPATLTTADLGEESTTFPSSS--GSTGTKLSPARST 891
Query: 1064 SPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELAS-RSPIRQDRGEFS 1122
+ +++ + S +E+ +L S T+P S S T S RSP S
Sbjct: 892 TSGLVGESTPSRLSPSSTETTTLPG-SPTTP----SLSEKSTTFYTSPRSP----DATLS 942
Query: 1123 ASPMLKSGMSPEQSRFQSD-----SSSYPTVDSNSLLGQ--SRLETAESKEKMALPPQED 1175
+ SG+S E S S ++++P + S L Q + +++ + L P
Sbjct: 943 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGST 1002
Query: 1176 ATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQD 1235
+S +Q F P E++L+ DT+ + E S S + P SS
Sbjct: 1003 TASSLGQQSTTFHSSP--GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS-- 1058
Query: 1236 EELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEA 1295
S+ L+E ST+ F+S P S S +
Sbjct: 1059 --------------------TSAGLQEESTT-FQSWPS-------SSDTTPSPPGTTAAP 1090
Query: 1296 VEVP----SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEV 1351
VEV S SS HFS L S SP G GT +
Sbjct: 1091 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP------GATGTAL-------- 1136
Query: 1352 KEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMS--SNQSISSPVLDA 1409
F + T + S SSG + + P + AG+S S SSP
Sbjct: 1137 -------FPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD 1189
Query: 1410 VPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSS-----PGLRDGSGTPSRHSLSGSSP 1464
+P+ SS S + + SR GS+ PG G + S SSP
Sbjct: 1190 TTLSPASTTSSGVSE--------ESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1241
Query: 1465 GMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVD 1524
G D +P S SS P++ P S + N + SS
Sbjct: 1242 GSTDTTLSPG---STTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTG 1298
Query: 1525 QKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPE 1584
+P G +R G S PS+ D+ P T + + S SP
Sbjct: 1299 SPHTTLSPAGSTTRQGESTTFQSWPSS-------KDTMPAPPTTTSAFVELSTTSHGSPS 1351
Query: 1585 VDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKG 1644
+ S + G S E ++P A + ++P P L S + SS G
Sbjct: 1352 STPTTHFSASSTTLGRSEE-STTVHSSPVATA---TTPSPARSTTSGLVEESTAYHSSPG 1407
Query: 1645 RGPS---PEGSSSTESSPEHPPKSRTARRGSRSSP--------EPKTKSRTPPRRRSSRS 1693
+ PE S+++ S E S ++ + SSP E T + P ++
Sbjct: 1408 STQTMHFPESSTASGRS-EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTH 1466
Query: 1694 SPELTRKARLSRRSRSASSSPETRSRTP-PRH 1724
PE + + S S ++ SSP+T TP P H
Sbjct: 1467 FPESSTTSGRSEESTASHSSPDTNGITPLPAH 1498
Score = 122 bits (306), Expect = 5e-27
Identities = 341/1582 (21%), Positives = 553/1582 (34%), Gaps = 187/1582 (11%)
Query: 1254 SHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPE 1313
S S +E +T + ++ P+ + L + +SL + E S S E
Sbjct: 7 STTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEE 66
Query: 1314 HKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKE 1373
K +SP + P S +G + SS E P T P L K
Sbjct: 67 SKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST---TKPGLSEKS 123
Query: 1374 QSTRSSG------HSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTP-----SRERSSSA 1422
+ SS H + ++ V + +S+ S A P + S+E ++S
Sbjct: 124 TTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASH 183
Query: 1423 SSPEMKDGLPRTPSRRSRS--------GSSPGLRDGSGTPSRHSLSG---SSPGMKDIPR 1471
SSP D S + S S PG + + P + SG +S + R
Sbjct: 184 SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTR 243
Query: 1472 TPSRGRSECDSSP---EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528
+P S S+ E P + P+ P + + P GS SS+ +
Sbjct: 244 SPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHI 303
Query: 1529 AR--TPLG-------QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS 1579
+ T G S GS+Q + S + R E +S+ + T T S +
Sbjct: 304 SARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGE-ESTTSHSSTTHTISSAPSTT 362
Query: 1580 GSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSG 1639
+ E + SP + + P D + R++ + S A LP RS +
Sbjct: 363 SALVEEPTSYHSSPGSTATTHFP---DSSTTSGRSEESTASHSSQDATGTIVLPARSTTS 419
Query: 1640 SSSKGRGPSPEGSSSTE---------------------SSPEHPPKSRT-ARRGSRSSPE 1677
SP S S E SSP P + + A S E
Sbjct: 420 VLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSE 479
Query: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737
T SR+ P + + P+ T LSR S ++ SSP + T + S S E
Sbjct: 480 ESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTT 539
Query: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQ-- 1795
SS +A SP + T G+ + + S T TT D + SS
Sbjct: 540 SHSSSGSTDTALSPGSTTALSFGQ---------ESTTFHSNPGSTHTTLFPDSTTSSGIV 590
Query: 1796 STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR 1855
S R S R T S S SP Q S T+ + + T P+ + +
Sbjct: 591 EASTRVHSSTGSPRTTL-----SPASSTSPGLQGES-TAFQTHPASTHTTPSPPSTATAP 644
Query: 1856 TSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSP-VSRRRSRSRTSVTRRRSRSR 1914
+ ++P TH + S T S + + +SP S S S T R S
Sbjct: 645 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 704
Query: 1915 ASPVSRRRSRSRTPP-----------VTRRRSRSRTPTTRRRSRSRTP-PVTRRRSRSRT 1962
S +S + T P T S R+PTT S T V + SR+
Sbjct: 705 TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 764
Query: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS--PVTRRRSRSRTSPVTRRRSRS 2020
P + + S S T S T+ + R + T+ P + S P T +
Sbjct: 765 QPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPA 824
Query: 2021 RTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSA 2080
T + + + L + SP + + + G+ S T + +
Sbjct: 825 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS----GS 880
Query: 2081 SGSSSDRSRSATPPATRNHSGSRTPPVALNSSRM-SCFSRPSMSPTPLDRCRSPGMLEP- 2138
+G+ +RS T + SR P + ++ + + PS+S SP +
Sbjct: 881 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 940
Query: 2139 LGSSRTPMSVLQQAGGSMMDGPGPR----IPDHQRTS-VPENHAQSRIALALTAISLGTA 2193
L + T S + + + PG PD TS + + S + T +L
Sbjct: 941 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS-- 998
Query: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTA 2253
P S +A+ L + + + ++P + +P + + L A TP +
Sbjct: 999 --PGSTTASSLGQQST---------TFHSSPGDTETTLLPDDTITS-GLVEASTPTHSST 1046
Query: 2254 VNLADSRTPAAAAAMNLASPRTAVA--PSAVNLADPRTPTAPAVNLAGARTPAALAALSL 2311
+L + TPA++ + L T PS+ + TP+ P T AA +S
Sbjct: 1047 GSLHTTLTPASSTSAGLQEESTTFQSWPSSSDT----TPSPPG-------TTAAPVEVST 1095
Query: 2312 TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM 2371
T P SS+ T AS+ +G RS +T + G+ A S TS
Sbjct: 1096 TYHSRP-------SSTPTTHFSASSTTLG-RSEESTTVHSSPGATGTALFPTRSATSV-- 1145
Query: 2372 APALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRM 2431
L G TSP SG T L + + S S + +S R+P +
Sbjct: 1146 ---LVGEPTTSPIS--------SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT--- 1191
Query: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS--SAGD 2489
L PA + + SR TT GS ++ + +T S S G
Sbjct: 1192 --------LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 1243
Query: 2490 HNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549
+ LS PG + P ++T P + +S +S+ SS+ S
Sbjct: 1244 TDTTLS---PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP 1300
Query: 2550 SSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSS 2609
++ S +GS++ E ++ P + +P+P P A E S++
Sbjct: 1301 HTTLSPAGSTTRQGESTTFQSWPS-SKDTMPAP-PTTTSAFVE-------------LSTT 1345
Query: 2610 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP 2669
S S SS+ ++ S+SS++ S S++ SS +++++PSPA+ L + ++
Sbjct: 1346 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 1405
Query: 2670 PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRS 2729
PG +++ P S RS SP S+ E + S +
Sbjct: 1406 PGS--TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIA 1463
Query: 2730 PSHKRRRETPSPRPMRHRSSRS 2751
+H T S R +S S
Sbjct: 1464 TTHFPESSTTSGRSEESTASHS 1485
Score = 116 bits (291), Expect = 3e-25
Identities = 376/1758 (21%), Positives = 595/1758 (33%), Gaps = 215/1758 (12%)
Query: 925 PRQRSHSGSSSPSPS-----RVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKV 979
P + SG S S + T +TP + +++ S S +H SS +
Sbjct: 4 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63
Query: 980 KPETPPRQSHSGSISPYPKVKAQTPPGPS---LSGSKSPCPQEKSKDSLVQSCPGSLSLC 1036
E+ + SHS SP P G + L G +P P GS+
Sbjct: 64 SEES--KASHS---SPDAMATTVLPAGSTPSVLVGDSTPSPISS----------GSMETT 108
Query: 1037 AGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKG 1096
A S+T PG S + T+ S TSS +S + S T+ G
Sbjct: 109 ALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG 168
Query: 1097 GRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQ 1156
+ AS S S S + PE + F S S T +LL
Sbjct: 169 STTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTET----TLLPD 224
Query: 1157 SRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVF------KDTLRTPP 1210
+ T S A P +T SP SP R S F KDT PP
Sbjct: 225 N---TTASGLLEASMPVHSSTRSP---HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPP 278
Query: 1211 RERSGAGSSPETKEQNS--ALPTS--SQDEELMEVVEKSEEPAGQILSHLSSELKEMSTS 1266
S A P T S ++PT+ S +VE+S S + E T+
Sbjct: 279 TTTS-AFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT 337
Query: 1267 NFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGP---HF------SPEHKEL 1317
+ + + T+ + S S E S SS G HF S +E
Sbjct: 338 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 397
Query: 1318 SNSPLRENSFGS---PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQ 1374
+ S +++ G+ P S LG + SS E P T P L +
Sbjct: 398 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST---TTPGLSERST 454
Query: 1375 STRSSGHS-SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL-- 1431
+ SS S ++ LSP + +G+S T SR R S + D
Sbjct: 455 TFHSSPRSPATTLSPASTTSSGVSEES------------TTSRSRPGSTHTTAFPDSTTT 502
Query: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491
P + S SSPG D + P+ + SG P + S G ++ SP
Sbjct: 503 PGLSRHSTTSHSSPGSTDTTLLPASTTTSG--PSQESTTSHSSSGSTDTALSPGSTTALS 560
Query: 1492 TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSA 1551
+ + S+P + L P + + S V+ T + G + L S
Sbjct: 561 FGQESTTFHSNPGSTHTTLFP--DSTTSSGIVEASTRVHSSTGSPRTT-----LSPASST 613
Query: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA 1611
SP + ES + A T T S + + E + SP GS+P +
Sbjct: 614 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP-----GSTPTTHFPASST 668
Query: 1612 PRAQSGSD----SSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT 1667
S SSP+ P S + S++ GRG S S S+ T
Sbjct: 669 TSGHSEKSTIFHSSPDASGTTP------SSAHSTTSGRGESTTSRISPGST------EIT 716
Query: 1668 ARRGSRSSP---EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP-ETRSRTPPR 1723
GS ++P E T + PR ++ SP + S ++ S P T S P
Sbjct: 717 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 776
Query: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783
+P +S S S + P + TTS G P+ SR T
Sbjct: 777 STTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTT---------FHSRPASTH 827
Query: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843
TT + S +S T + P S++T G
Sbjct: 828 TTLFTEDSTTSGLTEES---------------------TAFPGSPASTQT------GLPA 860
Query: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
T T+ S T P+ + ++ SPA RS T + + SR SP S
Sbjct: 861 TLTTADLGEESTTFPSSSGSTGTKLSPA-----RSTTSGLVGESTPSRLSP-------SS 908
Query: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP 1963
T T +S + + T P + + S TT + V+ S S +
Sbjct: 909 TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT-------SSGVSEESSTSHSQ 961
Query: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP 2023
P + + S T S+ P T S+ T S + +S + + +P
Sbjct: 962 PGSTHTTAFPDSTTTSDLSQE---PTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 1018
Query: 2024 PAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGS 2083
+ T LLP S A S ++ G T +P +
Sbjct: 1019 ------GDTETTLLPDDTITSGLVEA------STPTHSSTGSLHTTLTPASSTSAGLQEE 1066
Query: 2084 SSD-RSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSS 2142
S+ +S ++ T + G+ PV ++++ SRPS +PT S LG S
Sbjct: 1067 STTFQSWPSSSDTTPSPPGTTAAPVEVSTTY---HSRPSSTPTTHFSASST----TLGRS 1119
Query: 2143 RTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAA 2202
+V G + P TSV + +++ S T P S + A
Sbjct: 1120 EESTTVHSSPGATGT----ALFPTRSATSVLVGEPTTS---PISSGSTETTALPGSTTTA 1172
Query: 2203 GLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNL-ASARTPAIPTAVNLADSRT 2261
GL+ + + + +PA+ +S + S + + S T A P + +
Sbjct: 1173 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ 1232
Query: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA 2321
+ A+ + S T ++P + A P + + + T L + T SG +
Sbjct: 1233 ESTASHSSPGSTDTTLSPGSTT-ASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEAST 1291
Query: 2322 NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSA--RMAPALSGAN 2379
SS+ +P S R +T + S+ AP + TSA ++ G+
Sbjct: 1292 PVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP-APPTTTSAFVELSTTSHGSP 1350
Query: 2380 LTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSL 2439
++P SA GR+ + + PS +R T+ S+ +P +
Sbjct: 1351 SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST- 1409
Query: 2440 LPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAP 2499
P S S S++SR + TT S ++ A+ +S H+ S+
Sbjct: 1410 --QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSY--HSSPGSIATT 1465
Query: 2500 GVPHSDV--GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSG 2557
P S G ST + + P ++S + S++ S S ++ +S
Sbjct: 1466 HFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLAST 1525
Query: 2558 SSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS 2617
+++ S + V PT P PT SSS+S + S
Sbjct: 1526 ATTPGLSAKSTILYTS---DLVGEPTTFYIS-------PSPTYTTLFPASSSTSGLTEES 1575
Query: 2618 SSSSSSSSSSSSSSSSSS 2635
++ +S S +S+ S+ S
Sbjct: 1576 TTFHTSPSFTSTIVSTES 1593
Score = 111 bits (277), Expect = 1e-23
Identities = 344/1608 (21%), Positives = 558/1608 (34%), Gaps = 257/1608 (15%)
Query: 1216 AGSSPETKEQNSA-LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES--SP 1272
AGS+P +S P SS E + + +P L E ST+ + S SP
Sbjct: 84 AGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPG----------LSEKSTTFYSSPRSP 133
Query: 1273 EVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLE 1332
+ PA + S+ + + + +++ G P + S + S SP
Sbjct: 134 DTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTA-----SHSSP-- 186
Query: 1333 FRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPS---LDMKEQSTRSSG--------H 1381
GP T ++ G S L GP + P + +T +SG H
Sbjct: 187 ----GPTDTTLSPG--STTASSL-GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVH 239
Query: 1382 SSSELSPDAVEKAGMSSNQSISSP---------VLDAVPRTPSRERSSSASSPEMKDGLP 1432
SS+ + AG ++ Q S+ A P T S S +S +P
Sbjct: 240 SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIP 299
Query: 1433 RTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE------------C 1480
T S ++ GL + S T HS GS+ M + GR E
Sbjct: 300 TT--HISARSTTSGLVEESTT--YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTI 355
Query: 1481 DSSPEP-KALPQTPRPRSRSPSSPELNN---KCLTPQRERSGSESSVDQKTVARTPLGQR 1536
S+P AL + P SP S + T R + S Q L R
Sbjct: 356 SSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPAR 415
Query: 1537 SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRS 1596
S ++ L + + SP +++ + T L +RS + S + LSP +
Sbjct: 416 S---TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 472
Query: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR----------- 1645
S E R+ P + ++ P + L R S + SS G
Sbjct: 473 TSSGVSEESTTSRSRP---GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 529
Query: 1646 --GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
GPS E ++S SS + S + T + P + P+ T + +
Sbjct: 530 TSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGI 589
Query: 1704 SRRS-RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT-----TS 1757
S R SS+ R+ P SP + A ++ + + S P T T ++
Sbjct: 590 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 649
Query: 1758 RRGRSPSPKPRGLQRSRSRSRREKTRTT---RRRDRSGSSQSTSRRRQRSRSRSRVTRRR 1814
RSP P + S + ++T D SG++ S++ R S +R
Sbjct: 650 TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 709
Query: 1815 RGGSGY-----HSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR-SRA 1868
G + + +P E+S T R PT+ S TS + S SR+
Sbjct: 710 PGSTEITTLPGSTTTPGLSEASTTFYSSPRS-----PTTTLSPASMTSLGVGEESTTSRS 764
Query: 1869 SPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP 1928
P + + S + S T+ S R + T+V P S S
Sbjct: 765 QPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVF---------PHSTTTSVHGEE 815
Query: 1929 PVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSP 1988
P T + T TT S T +T + P + + T S T P
Sbjct: 816 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFP 875
Query: 1989 VTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPL 2048
+ + ++ SP +RS TS + + SR P S + T LP SP
Sbjct: 876 SSSGSTGTKLSP-----ARSTTSGLVGESTPSRLSP-----SSTETTTLPG------SPT 919
Query: 2049 AIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVA 2108
+S T T+ T SP ++SG S + S S + P + + +
Sbjct: 920 TPSLSEKSTTFYTSPRSPDATLSPATT---TSSGVSEESSTSHSQPGSTHTTAFPDSTTT 976
Query: 2109 LNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQ 2168
+ S+ S S T + SPG T S L Q + PG D +
Sbjct: 977 SDLSQEPTTSHSSQGST--EATLSPGS--------TTASSLGQQSTTFHSSPG----DTE 1022
Query: 2169 RTSVPENHAQSRIALALTAI-----SLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTA 2223
T +P++ S + A T SL T P S ++AGL + + +
Sbjct: 1023 TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS 1082
Query: 2224 PAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAP--SA 2281
P A+ + ++ +S T + + + + TA+ P SA
Sbjct: 1083 PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 1142
Query: 2282 VNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQ---APASANL 2338
++ T+P ++ T S T +G + + SS R+P +PAS
Sbjct: 1143 TSVLVGEPTTSP---ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTS 1199
Query: 2339 VG-----------PRSAHATA------PVNIAGSRTAAALAPASLTSARMAPALSGANLT 2381
G P S H TA ++ TA+ +P S T ++P + A+
Sbjct: 1200 SGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS-TDTTLSPGSTTASSL 1258
Query: 2382 SPRVPLSAYERVSGRTSPPLLDR-------ARSRTPPSAPSQSRMTSERAPSPSSRMGQA 2434
P + + G T LL + TP + + S T+ ++R G++
Sbjct: 1259 GPES--TTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES 1316
Query: 2435 PSQSLLPPAQDQPRSP--VPSAFSDQSRCLIAQ--TTPV----AGSQSLSSGAVATTTSS 2486
+ P ++D +P SAF + S +TP A S +L +TT S
Sbjct: 1317 TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 1376
Query: 2487 AGDHNGMLSVPAPGVPHSDVGEPPA---STGAQQ----PSALAALQPAKERRSSSSSSSS 2539
+ PA V E A S G+ Q P + A ++E R+S SS++
Sbjct: 1377 SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTH 1436
Query: 2540 SSSSSSSSSSS------SSSSSSGSSSSDS--EGSSLPVQPEVALKRVPSP-----TPAP 2586
+ SS S++S+ S SS GS ++ E S+ + E + SP TP P
Sbjct: 1437 TISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLP 1496
Query: 2587 KEAVREGRPPEPT-----PAKRKRRSSSSSSS---------------------------- 2613
GR E T P + +S++++
Sbjct: 1497 AHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSP 1556
Query: 2614 --------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653
SSS+S + S++ +S S +S+ S+ S + + +P K
Sbjct: 1557 TYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPETPEK 1604
Score = 99.0 bits (245), Expect = 6e-20
Identities = 276/1281 (21%), Positives = 441/1281 (34%), Gaps = 184/1281 (14%)
Query: 263 STSADSASSSDTSRSRSR-SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR- 320
ST SDT+ R S + + TT +PS S E + S PG+T+T
Sbjct: 325 STQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF 384
Query: 321 PSSPETATKQPSSPYEDKDKDKK---------------EKSATRPSPSPERSSTGPEPPA 365
P S T+ + S +D +S T P S +T
Sbjct: 385 PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST 444
Query: 366 PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL-----PQSSSSES 420
TP L+ER +T P +P + SP S S E P S+ + +
Sbjct: 445 TTPGLSER---------STTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTA 495
Query: 421 SPPSPQPTKVSRHASSSPESPKPA-----PAPGSHREISSSPTSKNRSHGRAKRDKSHSH 475
P S +SRH+++S SP PA + S T+ + S G S
Sbjct: 496 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGS 555
Query: 476 TPSRRMGRSRSPATAKRGRSRSR------------TPTKRGHSRSRSPQWRRSRSAQRWG 523
T + G+ + + G + + + R HS + SP+ S ++
Sbjct: 556 TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS---- 611
Query: 524 RSRSPQRRGRSRSPQ-RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSR-SRTPARR 581
S SP +G S + Q P + + + + ++ RSP + + +
Sbjct: 612 -STSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 670
Query: 582 GRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPA 641
G S T + T + S T R + SR T P + S A
Sbjct: 671 GHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA 730
Query: 642 RRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGR 701
+ S R+P S T G + + ++ + +PA S T
Sbjct: 731 STTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA------STTTPGLS 784
Query: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761
S ++ R + T + +S + + R + ++++ + S S S
Sbjct: 785 EESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES 844
Query: 762 LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP 821
+ P S A ++ L +L+ + ++S T P S SGS+ K P RS +S
Sbjct: 845 TAFPGSPASTQTGLPATLTTAD--LGEESTTFP--SSSGSTGTKLS----PARSTTSG-- 894
Query: 822 PPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSV---TPQRRSCFESSPD 878
TPSR S SS+ T GS T+P +E+S T R SP
Sbjct: 895 --LVGESTPSRLSPSSTE--------TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 944
Query: 879 PELKSRTPSRHSCSGSSP--------PRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSH 930
S S S S P P +++ Q P+ S S Q +A +SP
Sbjct: 945 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSP---GS 1001
Query: 931 SGSSSPSPSRVTSRTTPRRSR-SVSPCSNVESRLLPRY--SHSGSSSPDTKVKPETPPR- 986
+ +SS T ++P + ++ P + S L+ +HS + S T + P +
Sbjct: 1002 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA 1061
Query: 987 --QSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTP 1044
Q S + +P TP P + + P E S + S P SSTP
Sbjct: 1062 GLQEESTTFQSWPSSSDTTPSPPGTTAA----PVEVS--TTYHSRP----------SSTP 1105
Query: 1045 PGESYFGVSSLQLKGQSQTSPDHRS-DTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSS 1103
++F SS L +++ H S + + + S + L + TSP S ++
Sbjct: 1106 --TTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETT 1163
Query: 1104 PVTELASRSPIRQDRGEFSASP-----------MLKSGMSPEQSRFQSDSSSYPTV---D 1149
+ + + + + F +SP SG+S E + S S T
Sbjct: 1164 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 1223
Query: 1150 SNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTP 1209
S ++ G S+ TA P D T SP T +
Sbjct: 1224 STTMPGVSQESTASHSS----PGSTDTTLSPG---------------------STTASSL 1258
Query: 1210 PRERSGAGSSPETKEQNSALPTSSQDEELMEV---VEKSEEPAGQILSHLSSELKEMSTS 1266
E + SSP + E + LP ++ L+E V S LS S ++ ++
Sbjct: 1259 GPESTTFHSSPGSTE-TTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST 1317
Query: 1267 NFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENS 1326
F+S P ++ T + + S + PS + HFS L S
Sbjct: 1318 TFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPT---THFSASSTTLGRSEESTTV 1374
Query: 1327 FGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSEL 1386
SP+ + +G E + P Q ++ E ST S S
Sbjct: 1375 HSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQ-----TMHFPESSTASGRSEESRT 1429
Query: 1387 SPDAVEKAGMSSNQSISSP--VLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR---- 1440
S S+ +ISSP A+ P+ SS S T S RS
Sbjct: 1430 SHS-------STTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTA 1482
Query: 1441 SGSSPGLRDGSGTPSRHSLSG 1461
S SSP + P+ + SG
Sbjct: 1483 SHSSPDTNGITPLPAHFTTSG 1503
Score = 99.0 bits (245), Expect = 6e-20
Identities = 282/1254 (22%), Positives = 441/1254 (35%), Gaps = 151/1254 (12%)
Query: 236 SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRS 295
S+R + RS +TT +P S +TS+ + S TSRSR THTTA +
Sbjct: 450 SERSTTFHSSPRSPATTLSPAS-----TTSSGVSEESTTSRSRP----GSTHTTAFPDST 500
Query: 296 PSPASGRRGEGDAPFSEPGTT-STQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSP 354
+P R S PG+T +T P+S T S P ++ +T + SP
Sbjct: 501 TTPGLSR--HSTTSHSSPGSTDTTLLPASTTT-----SGPSQESTTSHSSSGSTDTALSP 553
Query: 355 ---------ERSSTGPEPPAP--TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDR 403
+ S+T P T L + S A+T + +P + SP
Sbjct: 554 GSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 613
Query: 404 SPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS---HREISSSPTSK 460
SP E S++ ++ P S H + SP S AP S HR S+PT
Sbjct: 614 SPGLQGE----STAFQTHP-------ASTHTTPSPPSTATAPVEESTTYHRSPGSTPT-- 660
Query: 461 NRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQ 520
+H A S H+ + S A+ S T + RG S + +
Sbjct: 661 --THFPASSTTS-GHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 717
Query: 521 RWGRSRSPQRRGRS-------RSPQ---RPGWSRSRNTQRRGRSRSARRGRSHSR-SPAT 569
G + +P S RSP P S + ++ G +HS SPA+
Sbjct: 718 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS 777
Query: 570 RGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS---- 625
+ TP G S T SR T T S T + G + +R S
Sbjct: 778 -----TTTP---GLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 829
Query: 626 -----RTRSPVRRRSRS--RSPA-RRSGRSRSRTPARRGRSRSRTPARRGRSRSR-TPAR 676
T S + S + SPA ++G + T A G + P+ G + ++ +PAR
Sbjct: 830 LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPAR 889
Query: 677 --RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS 734
SG TP+R S + T S + + + T R + S S
Sbjct: 890 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 949
Query: 735 RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP 794
S+ S S+S P + + + P S S LS + S SS + + +P
Sbjct: 950 GVSEESSTSHSQP---------GSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPG 1000
Query: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS 854
+ S Q + P + ++ P S + + SS + TP S
Sbjct: 1001 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP---AS 1057
Query: 855 ITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS 914
TS E+S T F+S P S + + S G++ V+ ST P SS+
Sbjct: 1058 STSAGLQEESTT------FQSWP-----SSSDTTPSPPGTTAAPVEVSTTYHSRP--SST 1104
Query: 915 PQPKVKAIISPRQRSHSGSS-SPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSS 973
P A + RS ++ SP + P RS + P S S
Sbjct: 1105 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE------PTTSPISSG 1158
Query: 974 SPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSL 1033
S +T P + S + + + P +LS + + + + S PGS
Sbjct: 1159 STETTALPGSTTTAGLSEKSTTF--YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1216
Query: 1034 SLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSS---PEVRQSHSESPSLQSK- 1089
A S+T PG S +S G + T+ S T+S PE HS S ++
Sbjct: 1217 HTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL 1276
Query: 1090 -SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV 1148
+ G +S+PV ++ SP + SP + E + FQS SS T+
Sbjct: 1277 LPDNTTASGLLEASTPV-HSSTGSP------HTTLSPAGSTTRQGESTTFQSWPSSKDTM 1329
Query: 1149 DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRT 1208
+ + +E + + + +S P S + ES+ V + T
Sbjct: 1330 PAPPTTTSAFVELSTT--------SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 1381
Query: 1209 PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268
++ E+++A +S + M E S S S ST++
Sbjct: 1382 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTS----HSSTTHT 1437
Query: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG 1328
SSP V S S+ P +++ G S E +SP
Sbjct: 1438 ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGR---SEESTASHSSPDTNGITP 1494
Query: 1329 SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG----HSSS 1384
P F SG + E T + S + L T P L K +S ++
Sbjct: 1495 LPAHFTTSGRI-AESTTFYISPGSMETT---LASTATTPGLSAKSTILYTSDLVGEPTTF 1550
Query: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL-PRTPSR 1437
+SP ++ S S ++ S +S+ S E + L P TP +
Sbjct: 1551 YISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPETPEK 1604
Score = 96.7 bits (239), Expect = 3e-19
Identities = 306/1410 (21%), Positives = 481/1410 (34%), Gaps = 203/1410 (14%)
Query: 752 SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP 811
S ISS + + P S K LS + + SSP + P + SG S+ S +
Sbjct: 98 SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 157
Query: 812 PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS-------------P 858
P + +++ P + S SSP P + +P GS T+ P
Sbjct: 158 PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP---GSTTASSLGPEYTTFHSRP 214
Query: 859 QANEQSVTPQRRSC---FESSPDPELKSRTP-SRHSCSGSSPPRVKSSTPPRQSPSRSSS 914
+ E ++ P + E+S +R+P + S +GS+ + +S+T S+ +
Sbjct: 215 GSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTR 274
Query: 915 PQP--KVKAIISPRQRSHSGSSSPSPSRVTSRTTPR----------------------RS 950
P P A + P SH SS + +++R+T S
Sbjct: 275 PAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPES 334
Query: 951 RSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLS 1010
+ S + +H+ SS+P T P HS SP P + S
Sbjct: 335 DTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHS---SPGSTATTHFPDSSTTS 391
Query: 1011 GSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSD 1070
G +E + Q G++ L A +S GES +S G +T+ S
Sbjct: 392 GRS----EESTASHSSQDATGTIVLPARSTTSVLLGES---TTSPISSGSMETTALPGST 444
Query: 1071 TSSPEVRQSHSESPSLQSKSQT-SPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKS 1129
T+ +S + S +S + T SP S +SS V+E ++ S R +A P S
Sbjct: 445 TTPGLSERSTTFHSSPRSPATTLSP---ASTTSSGVSEESTTSRSRPGSTHTTAFP--DS 499
Query: 1130 GMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEK-----------MALPPQEDATA 1178
+P SR + S S P +LL S + S+E AL P
Sbjct: 500 TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTAL 559
Query: 1179 SPPRQKDKFSPFP-------VQDRPESSLVFKDTLR------TPPRERSGAGS-SPETKE 1224
S ++ F P D SS + + + R +P S A S SP +
Sbjct: 560 SFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG 619
Query: 1225 QNSAL------------PTSSQDEELMEVVEKSEEPAGQILSHL-----SSELKEMSTSN 1267
+++A P S+ + E P +H +S E ST
Sbjct: 620 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI- 678
Query: 1268 FESSPEV------EERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSP 1321
F SSP+ S + + S+ S + E+ ++ S P S +SP
Sbjct: 679 FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP 738
Query: 1322 LRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGH 1381
+ SP + G +G E T S + T P L + + SS
Sbjct: 739 RSPTTTLSPASMTSLG-VGEESTT--SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSR 795
Query: 1382 SSSE---------LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSP----EMK 1428
S+E S E S + + L T S S + P +
Sbjct: 796 GSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ 855
Query: 1429 DGLPRTPSRRSRSGSSPGLRDGSG------TPSRHSLSGSSPGMKDIPRTPSRGRSECDS 1482
GLP T + S SG +P+R + SG TPSR S
Sbjct: 856 TGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVG-----ESTPSR---LSPS 907
Query: 1483 SPEPKALPQTPRPRS---------RSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL 1533
S E LP +P S SP SP+ T ESS T
Sbjct: 908 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 967
Query: 1534 GQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSP 1593
S ++ +L +P+ S + ++++ + T + L Q+S + S D+++ L P
Sbjct: 968 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1027
Query: 1594 RRSRSGSSPEVKDKPRAAPRAQSGS-DSSPEPKAPAPRALPRRS---RSGSSSKGRGPSP 1649
+ + E + +GS ++ P + L S +S SS PSP
Sbjct: 1028 DDTITSGLVEAS----TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 1083
Query: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
G+++ P + SR S P T S SS L R S S +
Sbjct: 1084 PGTTAA-------PVEVSTTYHSRPSSTPTT--------HFSASSTTLGR----SEESTT 1124
Query: 1710 ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR-------S 1762
SSP R + SV EP SS + + P + TT+ S
Sbjct: 1125 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 1184
Query: 1763 PSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
P L + + S +T R GS+ +T+ + G
Sbjct: 1185 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTM------------PGVSQ 1232
Query: 1823 RSPARQES-SRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881
S A S T + G + + + +SP + + + + TP
Sbjct: 1233 ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTP 1292
Query: 1882 LISRRRSRSRT-SPV--SRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
+ S S T SP + R+ S T + S+ S T S S
Sbjct: 1293 VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSS 1352
Query: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPV----TRRRSRSRTSPITRRRSRSRTSP-VTRRR 1993
TPTT + S T + + + PV T +RS TS + + +SP T+
Sbjct: 1353 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM 1412
Query: 1994 SRSRTSPVTRRRSRSRTSPVTRRRSRSRTP 2023
+S + R SRTS + + S P
Sbjct: 1413 HFPESSTASGRSEESRTSHSSTTHTISSPP 1442
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 126 bits (317), Expect = 3e-28
Identities = 245/1003 (24%), Positives = 365/1003 (36%), Gaps = 133/1003 (13%)
Query: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
DG P + + P+P P SSSS SP P R + P
Sbjct: 181 DGGPAPPPAPSSASSSPSPSP---------SSSSPSPPPPPPPPAPPAPPAPRFDIYDPF 231
Query: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266
++ S + ++K+ P S S + TP+P+
Sbjct: 232 HPTDEAY------SPPPAPEQKYDPFEPTGSNPS-------SSAGTPSPEEEEEEEEEEE 278
Query: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPET 326
+ + S+S + + T LAG + + GD P TQ +P T
Sbjct: 279 EEEEDEEEEEGLSQSISRISET--LAGIYDDNSLSQDFPGDES-PRPDAQPTQPTPAPGT 335
Query: 327 ATKQPSSPYEDKDKDK-----KEKSATRPSPSPERSSTGPEPPAPTPLLAE-----RHGG 376
+ S+ + + + E A R T P PLL G
Sbjct: 336 PPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGE 395
Query: 377 SPQPLATTPLSQEPVNPPSEAS-PTRDRSPPKSPEKLPQSSSSESSPPSPQPTK----VS 431
QP L+ P A+ PT S + + LPQ PP+P+ + +S
Sbjct: 396 IVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQ-------PPAPRAPEGDDFLS 448
Query: 432 RHASSSPESP------KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485
HA S E +PAPAP P + +R G R K + R RS
Sbjct: 449 LHAESDGEGALQVDLGEPAPAP---------PAADSRWGGLDLRRKILTQRRERYRQRSP 499
Query: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545
SPA A + + PT++ R R +RS A+ S S G +P P S
Sbjct: 500 SPAPAPAPAAAAGPPTRKKSRRER----KRSGEAKEAASSSS----GTQPAPPAPA---S 548
Query: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605
++ RSR + G S S R RSRSR +R R RSR+ RRR S RRSR
Sbjct: 549 PWDSKKHRSRDRKPGSHASSSARRRSRSRSR--SRSTRRRSRSTDRRRGGS-----RRSR 601
Query: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
SR RR R RS +P S + S RR R R R G S+ ++ RSRSR R
Sbjct: 602 SREKRRR-RRRSASPPPATSSSSS--SRRERHRGKHRDGGGSKK----KKKRSRSRGEKR 654
Query: 666 RGRSRSRTPARRSGRSRSRTPA-RRGRSRSRTPRRGRSRS-------RSLVRRGRSHSRT 717
G + PA S S + R R R P + + + + GR
Sbjct: 655 SGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSD 714
Query: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
P+ + +SS ++ S+ S KS RR +S S ++ + S R+
Sbjct: 715 PRGPSPAPASSPKREVLYDSEGLSGEERG---GKSSQKDRRRSGAASSSSSSREKGSRRK 771
Query: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
+L G R R +K PP+ S SS PPPK + S S SS
Sbjct: 772 ALDG--------GDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSS 823
Query: 838 SS-PHPKVKSGTPP----RQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892
SS KVK + R+G ++ A + + + S D E SR+P
Sbjct: 824 SSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRE--SRSPF----- 876
Query: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQ-RSHSGSSSPSPSRVTSRTTPRRSR 951
P + + +P + + KVKA ++ + G + PS +R R+
Sbjct: 877 -LKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGG 935
Query: 952 SVSPCSNVESRLLPRYSHSGSSSPDTKVKPETP-PRQSHSGSISPYPKVKAQTPPGPSLS 1010
S S +S+ + S S + TK ET + + + P KA PP P+L+
Sbjct: 936 SGGQVSLKKSK-----ADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKA-APPPPALT 989
Query: 1011 GSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSD 1070
S K V P + AGV+ E + + + + +
Sbjct: 990 -PDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEE---EEEEEEEEEEEEEQQPATT 1045
Query: 1071 TSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSP 1113
T++ + S +PS S + S G +S V++L + P
Sbjct: 1046 TATSTAAAAPSTAPSAGSTAGDS--GAEDGPASRVSQLPTLPP 1086
Score = 109 bits (273), Expect = 3e-23
Identities = 232/1046 (22%), Positives = 371/1046 (35%), Gaps = 166/1046 (15%)
Query: 1429 DGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSEC--DSSPEP 1486
DG P P S + SSP S +PS S S P P P R + P
Sbjct: 181 DGGPAPPPAPSSASSSP-----SPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTD 235
Query: 1487 KALPQTPRPRSR----SPSSPELNNKCLTPQRERSGSESSVDQK---------------- 1526
+A P P + P+ ++ TP E E +++
Sbjct: 236 EAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSIS 295
Query: 1527 TVARTPLGQRSRSGSSQEL----DVKPSASPQERSESDSSPDSKAKTRTPLRQRSR---S 1579
++ T G + SQ+ +P A P + + + +P TR R R
Sbjct: 296 RISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVV 355
Query: 1580 GSSPEVDSKSRLSPRRSRSGSSP-------------------EVKDKPRAA--------- 1611
G+ E + ++S +G + + +++PR A
Sbjct: 356 GTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGR 415
Query: 1612 -----PRAQSGSDSSPEPKAPAPRALPRRS---RSGSSSKGRG----------PSPEGSS 1653
P A + + P P+ PAPRA P + S G G P+P +
Sbjct: 416 AARPTPAASATPTAQPLPQPPAPRA-PEGDDFLSLHAESDGEGALQVDLGEPAPAPPAAD 474
Query: 1654 STESSPEHPPKSRTARRG--SRSSPEP-----KTKSRTPPRRRSSRSSPELTRKARLSRR 1706
S + K T RR + SP P + PP R+ SR + + +A+
Sbjct: 475 SRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAK-EAA 533
Query: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
S S+ + P + P + +P + SS RRRS S R+++T RR RS +
Sbjct: 534 SSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRR 593
Query: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR--------------RQRSRSRSRVTR 1812
G +RSRSR +R + R + + SS S+SRR +++ RSRSR
Sbjct: 594 RGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSR-GE 652
Query: 1813 RRRGGSGYHSRSPARQESSRTS--SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASP 1870
+R G + +PA S TS R R R PP+ + + + R
Sbjct: 653 KRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLD- 711
Query: 1871 ATHRRSRSRTPLISRRRSRSRTSP--VSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP 1928
+ R S P S +R S R + RRRS + +S S R SR
Sbjct: 712 KSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRK 771
Query: 1929 PV---TRRRSRSRTPTTRRRSRSRTPPVTRRRSRS--RTPPVT--RRRSRSRTSPITRRR 1981
+ R R R R R S+ PP S PPV+ S S +S +R+
Sbjct: 772 ALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKV 831
Query: 1982 SRSRTSPVTRRRSRSRTSPVTRRRSRSRTS-PVTRRRSRSRTPPAIRRRSRSRTPLLPRK 2040
V R S T+P S S V R R P ++ R+ T +
Sbjct: 832 KLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAA 891
Query: 2041 RSRSR-SPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDR-----------S 2088
++ ++ ++ ++ + +GK +++ +R SG S + S
Sbjct: 892 PGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCS 951
Query: 2089 RSATPPATRNHSGS---RTPPVALNSSRMSCFSRPSMSP---TPLDRCRSPGMLEPLGSS 2142
++A S S R V + P+++P T C++P + S
Sbjct: 952 QAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEV------S 1005
Query: 2143 RTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAA 2202
P ++AG + G + + E + + TA S A P + SA
Sbjct: 1006 FLPEEATEEAG---VRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAG 1062
Query: 2203 ----------GLAARMSQVPA-PVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIP 2251
G A+R+SQ+P P P+ A S + A +A + A +
Sbjct: 1063 STAGDSGAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRA 1122
Query: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSL 2311
A L A + S R PS++ + PT+ + G + +L L
Sbjct: 1123 KAQELIQ-------ATNQILSHRK--PPSSLGMTPAPVPTSLGLP-PGPSSYLLPGSLPL 1172
Query: 2312 TGSG-TPPTAANYPSSSRTPQAPASA 2336
G G TPPT ++S + +S+
Sbjct: 1173 GGCGSTPPTPTGLAATSDKREGSSSS 1198
Score = 105 bits (262), Expect = 6e-22
Identities = 217/912 (23%), Positives = 315/912 (34%), Gaps = 143/912 (15%)
Query: 253 PAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE 312
P P R+ S ++ SR A T T G +P PA +P
Sbjct: 143 PVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPS 202
Query: 313 PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE 372
+ S P P P+ ++ D A P P+PE+ +P PT
Sbjct: 203 SSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKY---DPFEPT----- 254
Query: 373 RHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSS----------SESSP 422
G +P A TP +E E + + E L QS S ++S
Sbjct: 255 --GSNPSSSAGTPSPEE--EEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSL 310
Query: 423 PSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMG 482
P S + P +P PAPG+ ++ S+ R+ G + RR+
Sbjct: 311 SQDFPGDESPRPDAQP--TQPTPAPGTPPQVDST-----RADGAMR----------RRVF 353
Query: 483 RSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR-SRSPQRPG 541
+ A A R S G + P S G P+ R + S RPG
Sbjct: 354 VVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPG 413
Query: 542 WSRSRNTQRRGRSRSARRGRSHSRSPATR------------------------GRSRSRT 577
+R T + +A + + PA R G
Sbjct: 414 GRAARPTPAASATPTA---QPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAP 470
Query: 578 PARRGR-----SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR 632
PA R R + +RR R R+RS S PA + + P R++SR R
Sbjct: 471 PAADSRWGGLDLRRKILTQRRER----YRQRSPSPAPAPAPAAAAGPPTRKKSR-----R 521
Query: 633 RRSRSRSPARRSGRSRSRTPA----------RRGRSRSRTPARRGRSRSRTPARRSGRSR 682
R RS + S PA ++ RSR R P S + + ARR RSR
Sbjct: 522 ERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPG----SHASSSARRRSRSR 577
Query: 683 SRTPARRGRSRSRTPRRG---RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR 739
SR+ + R RSRS RRG RSRSR RR R + P S SSS R+ + R +
Sbjct: 578 SRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPP--ATSSSSSSRRERHR-GKH 634
Query: 740 RSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC----PKQKSQTPPR 795
R S + K+SR + S ++ A + SGS+ C +++ PP
Sbjct: 635 RDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPA-----PPPSGSTSCGDRDSRRRGAVPPS 689
Query: 796 RSRSGSSQPKAKSR--TPPRRSRSSSSPPPKQKSKTPSRQ----SHSSSSPHPKVKSGTP 849
A R T R +S P + +P R+ S S KS
Sbjct: 690 IQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQK 749
Query: 850 PRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909
R+ S + ++ RR + + R R S K + PP++S
Sbjct: 750 DRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSS-------KKARPPKES- 801
Query: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSH 969
+ SS P PK P S SGSSS S S +SR +S+ S P
Sbjct: 802 APSSGPPPK------PPVSSGSGSSS-SSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDA 854
Query: 970 SGSSSPDTKVKPETPPRQSHSGSISP---YPKVKAQTPPG---PSLSGSKSPCPQEKSKD 1023
+ + VK + R+S S + P P A+ PG P + K+ +K+K
Sbjct: 855 ASAGLGSIGVK-FSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKG 913
Query: 1024 SLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSES 1083
+ ++ P K G S + LK S + T E E
Sbjct: 914 TKGKTKPSKTR-----KKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEE 968
Query: 1084 PSLQSKSQTSPK 1095
+ + S PK
Sbjct: 969 RAAKVPSTPPPK 980
Score = 67.8 bits (164), Expect = 1e-10
Identities = 61/237 (25%), Positives = 94/237 (39%), Gaps = 19/237 (8%)
Query: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS---SSSSSGSSSSDSEGS 2566
P + P+A QP R S + S + + ++DS
Sbjct: 419 PTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWG 478
Query: 2567 SLPVQPEVALKR-------VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSS 2619
L ++ ++ +R PSP PAP A G PP ++R+R+ S + ++SSSS
Sbjct: 479 GLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAG-PPTRKKSRRERKRSGEAKEAASSSS 537
Query: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPR 2679
+ + + +S S S S + S A+ ++ + S + RRSRS
Sbjct: 538 GTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTR------RRSRSTD 591
Query: 2680 KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
+ R SRS RRR S P P SSSS R RG+ D K++R
Sbjct: 592 RRRGGSRRSRSREKR--RRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKR 646
Score = 60.1 bits (144), Expect = 3e-08
Identities = 159/730 (21%), Positives = 249/730 (34%), Gaps = 152/730 (20%)
Query: 2152 AGGSMMDGPGPRIP----DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR 2207
AGG+ + P P +P + + + + + R+AL+L ARP P+ SA A
Sbjct: 374 AGGAAL--PPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQP 431
Query: 2208 MSQVPAPVPLMSLRTAPAAN----LASRIPAASAAAMNLASARTPAIPTA------VNLA 2257
+ Q PAP AP + L + A ++L PA P A ++L
Sbjct: 432 LPQPPAP-------RAPEGDDFLSLHAESDGEGALQVDLGEP-APAPPAADSRWGGLDLR 483
Query: 2258 DSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGT- 2316
SP A AP+ A P PT R+ A A S + SGT
Sbjct: 484 RKILTQRRERYRQRSPSPAPAPAPAAAAGP--PTRKKSRRERKRSGEAKEAAS-SSSGTQ 540
Query: 2317 --PPTAAN------YPSSSRTPQAPASANLV----------GPRSAHATAPVNIAGSRTA 2358
PP A+ + S R P + AS++ R + GSR +
Sbjct: 541 PAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRS 600
Query: 2359 AALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSR 2418
+ +P + ++ +S R + G S R+RSR + S
Sbjct: 601 RSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSE 660
Query: 2419 MTSERAPSPSSRMGQAPSQS----LLPPA----------------------QDQPRSPVP 2452
AP PS S +PP+ + PR P P
Sbjct: 661 KAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSP 720
Query: 2453 SAFSDQSRCLIAQTTPVAG-------SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS- 2504
+ S R ++ + ++G SQ + A ++SS+ G G
Sbjct: 721 APASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDR 780
Query: 2505 ----DVGEPPASTGAQQP--SALAALQPAKERRSSSSSSSSSSSSSSSS----------- 2547
D +S A+ P SA ++ P K SS S SSSSSSS SS
Sbjct: 781 DRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVL 840
Query: 2548 -----SSSSSSSSSGSS---------SSDSEGSSLPVQPEVAL-----KRVPSPTPAPKE 2588
SS++ + + S+ S D E S ++P+ K P T K
Sbjct: 841 IREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKT 900
Query: 2589 AVR--------EGRPPEPTPAKRKRRSSSSSSSSSSSSSSS---SSSSSSSSSSSSSSSS 2637
V+ +G + P+K +++ S S S S S + S S ++ + +
Sbjct: 901 KVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAE 960
Query: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPV- 2696
+S S ++ P+ P P+A P P P P + S + P S + + V
Sbjct: 961 ETSWSGEERAAKVPSTPPPKAAPPP--PALTPDSQTVDSSCKTPEVSFLPEEATEEAGVR 1018
Query: 2697 --------ERRRPSPQPSPRDQQ--------------SSSSERGSRRGQRGDSRSPSHKR 2734
E + +QQ S++ GS G G P+ +
Sbjct: 1019 GGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRV 1078
Query: 2735 RRETPSPRPM 2744
+ P PM
Sbjct: 1079 SQLPTLPPPM 1088
Score = 59.7 bits (143), Expect = 4e-08
Identities = 96/405 (23%), Positives = 135/405 (33%), Gaps = 69/405 (17%)
Query: 2399 PPLLDRARSRTPPSAPSQSRMTSERAPS---PSSRMGQ-APSQSLLPPAQDQPRSPVPSA 2454
PPLL S Q A S P R + P+ S P AQ P+ P P A
Sbjct: 381 PPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRA 440
Query: 2455 FSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSV------------------ 2496
+ + G+ + G A +A G L +
Sbjct: 441 PEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPS 500
Query: 2497 PAPGVPHSDVGEPP-----------ASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS 2545
PAP + PP + + S+ + QPA +S S S
Sbjct: 501 PAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDR 560
Query: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
S +SSS+ S S S S +R T + R R E KR+R
Sbjct: 561 KPGSHASSSARRRSRSRSRSRST--------RRRSRSTDRRRGGSRRSRSRE----KRRR 608
Query: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665
R S+S ++SSSSSS S S S + G + P PA
Sbjct: 609 RRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPA-- 666
Query: 2666 KKPPP------GERRSRSPRKPIDSLRD---------SRSLSYSPVER---RRPSPQP-- 2705
PPP G+R SR S++D R+++ +++ R PSP P
Sbjct: 667 --PPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPAS 724
Query: 2706 SPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
SP+ + SE S + G S +R S R + SR
Sbjct: 725 SPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSR 769
Score = 58.5 bits (140), Expect = 9e-08
Identities = 216/1110 (19%), Positives = 370/1110 (33%), Gaps = 189/1110 (17%)
Query: 740 RSRSNSSPEMKKSRISSRRSRSLSS-------PRSKAKSRLSLRRSLSGSSPCPKQKSQT 792
R+ SP+ SR + R +L + P + + + S S S SSP P
Sbjct: 155 RTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPP--- 211
Query: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSK------TPSRQSHSSSSPHPKVKS 846
PP + P+ P + + SPPP + K T S S S+ +P P+ +
Sbjct: 212 PPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEE 271
Query: 847 GTPPRQGSITSPQANEQSVTPQRRSCFES------------------SPDPELKSRTPSR 888
+ + E+ ++ E+ SP P+ + P++
Sbjct: 272 EEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQ---PTQ 328
Query: 889 HSCSGSSPPRVKSST-------------------------------------PPRQSPSR 911
+ + +PP+V S+ PP P
Sbjct: 329 PTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGD 388
Query: 912 SSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS---------PCSNVESR 962
S + + I+ P + S P +R TP S + + P +
Sbjct: 389 SEIEEGE---IVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDD 445
Query: 963 LLPRYSHS---GSSSPDT-KVKPETPPRQSHSGSISPYPKVKAQT-----------PPGP 1007
L ++ S G+ D + P P S G + K+ Q P P
Sbjct: 446 FLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAP 505
Query: 1008 SLSGSKSPCPQEKSKDSLVQS--CPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP 1065
+ + + P ++KS+ +S + S +G + + P S + S + + + +
Sbjct: 506 APAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPW--DSKKHRSRDRKPG 563
Query: 1066 DHRSDTSSPEVR-QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
H S ++ R +S S S +S+S +GG RS S R R+ R S
Sbjct: 564 SHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRS-------REKRRRRRRSASPP 616
Query: 1125 PMLKSGMSPEQSRFQSD----SSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASP 1180
P S S + R + S + G+ R K PP +T+
Sbjct: 617 PATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCG 676
Query: 1181 PRQKDKFSPFP--VQDRPESSL-VFKDTL------RTPPRERSGAGSSPETKEQNSALPT 1231
R + P +QD + L K T+ ++ PR S A +S +E
Sbjct: 677 DRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEG 736
Query: 1232 SSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQA 1291
S +E + +K +G S SS K + +R D+ + ++
Sbjct: 737 LSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDR-----DRDRDRS 791
Query: 1292 SLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEV 1351
S +A A S G P P +S +S S + + + + G SS
Sbjct: 792 SKKARPPKESAPSSGPPPKPPVSSGSGSSS--SSSSCSSRKVKLQSKVAVLIREGVSSTT 849
Query: 1352 K-EDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAV 1410
+D L + S D + +RS E +P + KA S + + V
Sbjct: 850 PAKDAASAGLGSIGVKFSRD---RESRSPFLKPDERAPTEMAKAAPGSTKPKKTKV---- 902
Query: 1411 PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDG--SGTPSRHSLSGSSPGMKD 1468
+ + + + + + K P ++ RSG G G S S+ + G K
Sbjct: 903 -KAKAGAKKTKGTKGKTK---PSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKG 958
Query: 1469 IPRTPSRGR---SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ 1525
T G ++ S+P PKA P P + +P S +++ C TP+ E++ +
Sbjct: 959 AEETSWSGEERAAKVPSTPPPKAAPPPP---ALTPDSQTVDSSCKTPEVSFLPEEATEE- 1014
Query: 1526 KTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV 1585
G R G ++E + + +E E + P + T T S + S+
Sbjct: 1015 -------AGVR---GGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGST 1064
Query: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAP----RAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641
S + G + V P P +G D + L + + +
Sbjct: 1065 AGDS-----GAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLA 1119
Query: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS----------- 1690
S+ + +++ S PP S G +P P T PP S
Sbjct: 1120 SRAKAQELIQATNQILSHRKPPSS----LGMTPAPVP-TSLGLPPGPSSYLLPGSLPLGG 1174
Query: 1691 SRSSPELTRKARLSRRSRSASSSPETRSRT 1720
S+P + R SSS E R T
Sbjct: 1175 CGSTPPTPTGLAATSDKREGSSSSEGRGDT 1204
Score = 48.1 bits (113), Expect = 1e-04
Identities = 40/147 (27%), Positives = 57/147 (38%), Gaps = 15/147 (10%)
Query: 2578 RVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637
R P P P P R A R ++ S S+SS + + + + + +
Sbjct: 137 RDPIPLPVPSLLPR-------LRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPA 189
Query: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPID---SLRDSRSLSYS 2694
SS+SSS S SPS + P P P P +P PP P P D S + Y
Sbjct: 190 PSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYD 249
Query: 2695 PVERRRPSPQ-----PSPRDQQSSSSE 2716
P E +P PSP +++ E
Sbjct: 250 PFEPTGSNPSSSAGTPSPEEEEEEEEE 276
Score = 45.1 bits (105), Expect = 0.001
Identities = 61/312 (19%), Positives = 104/312 (33%), Gaps = 55/312 (17%)
Query: 2403 DRARSRTPPSAPSQSRMTSERAPSP--SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 2460
DR RS P +S +S P P SS G + S S + + +S V +
Sbjct: 787 DRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREG-- 844
Query: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
++ TTP + S G++ S + P P P ST ++
Sbjct: 845 --VSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKV 902
Query: 2521 LAAL------------QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568
A +P+K R+ S S S S S + S ++
Sbjct: 903 KAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEET 962
Query: 2569 PVQPEVALKRVPS--------PTPA--------------------PKEAVREG------- 2593
E +VPS P PA P+EA E
Sbjct: 963 SWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAE 1022
Query: 2594 --RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
E + + ++++++S+++++ S++ S+ S++ S + +S S P
Sbjct: 1023 EEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLP 1082
Query: 2652 AKPGPQALPKPA 2663
P P PA
Sbjct: 1083 TLPPPMPWNLPA 1094
Score = 38.9 bits (89), Expect = 0.071
Identities = 69/347 (19%), Positives = 124/347 (35%), Gaps = 78/347 (22%)
Query: 2422 ERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA 2481
+ +P P ++ Q PP D R+ + R + T +++ G V+
Sbjct: 317 DESPRPDAQPTQPTPAPGTPPQVDSTRADGAM----RRRVFVVGTE----AEACREGKVS 368
Query: 2482 TTTSSAGDHNGMLSVPAPGVP--HSDVGEPPASTGAQQPS-ALAALQPAKERRSSSSSSS 2538
+AG ++P P +P S++ E ++P AL+ +P + ++S
Sbjct: 369 VEVVTAGG----AALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAAS 424
Query: 2539 SSSSSSSSSSSSSSSSSSGS------SSSDSEGSSLPVQPEVALKRVPSPTPAPKEA--- 2589
++ ++ + + G + SD EG+ +Q ++ P PAP A
Sbjct: 425 ATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGA---LQVDLG-----EPAPAPPAADSR 476
Query: 2590 -----VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
+R + R+R S + + + ++++ + S S + ++SSS
Sbjct: 477 WGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSS 536
Query: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ 2704
S + P+P P PASP R R P
Sbjct: 537 SGTQPAP--------PAPASPWDSKKHRSRDRKP-------------------------- 562
Query: 2705 PSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
S + +RR R SRS S +RR + R R SRS
Sbjct: 563 -------GSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRS 602
Score = 38.1 bits (87), Expect = 0.12
Identities = 30/142 (21%), Positives = 49/142 (34%), Gaps = 8/142 (5%)
Query: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
P P P+ R + + + S S+SS + + + + + + SS+ S P
Sbjct: 141 PLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPS 200
Query: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
P + P PPP +PR I +Y SP P+P +
Sbjct: 201 PSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAY--------SPPPAPEQKYDPFE 252
Query: 2716 ERGSRRGQRGDSRSPSHKRRRE 2737
GS + SP + E
Sbjct: 253 PTGSNPSSSAGTPSPEEEEEEE 274
Score = 37.4 bits (85), Expect = 0.21
Identities = 75/389 (19%), Positives = 116/389 (29%), Gaps = 88/389 (22%)
Query: 2410 PPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV 2469
PP APS + + +PS SS P PPA PR + F A + P
Sbjct: 186 PPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDE---AYSPPP 242
Query: 2470 AGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE 2529
A Q P P S G P ++ + +E
Sbjct: 243 APEQKYDP-----------------FEPTGSNPSSSAGTPSPEEEEEEEE-----EEEEE 280
Query: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK-- 2587
S S S S + + S S D G P + P+P P+
Sbjct: 281 EEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVD 340
Query: 2588 -------------------EAVREGR----------PPEPTPAKRKRRSSSSSSSSSSSS 2618
EA REG+ P P S
Sbjct: 341 STRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPE 400
Query: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA-------------------- 2658
+ S ++ + ++S++ ++ P P P P+A
Sbjct: 401 EEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQ 460
Query: 2659 --LPKPASPKKPPPGERR--SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSS 2714
L +PA PP + R R+ I + R R SP P+P P+P
Sbjct: 461 VDLGEPA--PAPPAADSRWGGLDLRRKILTQRRERYRQRSP----SPAPAPAPAAAAGPP 514
Query: 2715 SERGSRRGQR--GDSRSPSHKRRRETPSP 2741
+ + SRR ++ G+++ + P+P
Sbjct: 515 TRKKSRRERKRSGEAKEAASSSSGTQPAP 543
Score = 35.4 bits (80), Expect = 0.78
Identities = 35/153 (22%), Positives = 47/153 (30%), Gaps = 8/153 (5%)
Query: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585
PA SS+SSS S S SSSS S + + P SP PA
Sbjct: 184 PAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPA 243
Query: 2586 PKEAVREGRPPEPTPA--------KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637
P++ P P+ + + S S S S + +
Sbjct: 244 PEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAG 303
Query: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
+S S P P P A P +P P
Sbjct: 304 IYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTP 336
Score = 33.5 bits (75), Expect = 3.0
Identities = 41/189 (21%), Positives = 68/189 (35%), Gaps = 13/189 (6%)
Query: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
S S+SS + + G P P SP+P+P + PP P PA
Sbjct: 161 SPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAP 220
Query: 2606 RSSS-SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664
+ + + S + + S+ SSS+ +PSP + + +
Sbjct: 221 PAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEE 280
Query: 2665 PKKPPPGERRSRSPRKPIDSLR---DSRSLSY------SP---VERRRPSPQPSPRDQQS 2712
+ E S+S + ++L D SLS SP + +P+P P Q
Sbjct: 281 EEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVD 340
Query: 2713 SSSERGSRR 2721
S+ G+ R
Sbjct: 341 STRADGAMR 349
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 126 bits (317), Expect = 3e-28
Identities = 299/1547 (19%), Positives = 548/1547 (35%), Gaps = 231/1547 (14%)
Query: 237 KRKSKDK---KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
KRK+++ + K++R + P S + A++ ++ T R A T+++ L
Sbjct: 62 KRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPR------LASTNSSVLGA 115
Query: 294 RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS 353
PS + + A + G T P P T K + S
Sbjct: 116 DLPS---SMKEKAKAETEKAGKTGNSMPH-PATG---------------KTVANLLSGKS 156
Query: 354 PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLP 413
P +S+ EP A T L++E P V+ S + D S
Sbjct: 157 PRKSA---EPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS--------- 204
Query: 414 QSSSSESS---PPSPQPTKVSRHASSSPESPK--PAPAPGSHREISSSPTSKNRSHGRAK 468
SSS E+ PS +P +V + S+ ESP APAPG ++
Sbjct: 205 -SSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDV--------------- 248
Query: 469 RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP 528
TP + G AK+ S + + S +P RS + ++
Sbjct: 249 -------TPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRS-------QVKAS 294
Query: 529 QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588
++ + R+ P ++ T +G + + P G S+T A + S +
Sbjct: 295 EKILQVRAASAP----AKGTPGKGATPA---------PPGKAGAVASQTKAGKPEEDSES 341
Query: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSR 648
+ S S T +++ A+ S+ A SP R+ + +P ++G +
Sbjct: 342 SSEESSDSEEET-PAAKALLQAKASGKTSQVGAASAPAKESP--RKGAAPAPPGKTGPAV 398
Query: 649 SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708
++ A + S++ + S PA+ ++ +PR+G + +
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA---- 454
Query: 709 RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL-SSPRS 767
P++ G + + + + S+ S + S + +++ + + L SP+
Sbjct: 455 --------PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
Query: 768 KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS-----SSSPP 822
K S + + G+ P P K ++ G + ++S + S ++ P
Sbjct: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
Query: 823 PKQKSKTPSRQSHSSSSP--HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
++KS Q+ +SSP P K+G Q P N +S E S D
Sbjct: 567 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES--------SEESSDSA 618
Query: 881 LKSRTPSRHSCSGSSP----PRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS--- 933
P+ + + + P P+ K + P + + + S+ P +PR+ + S
Sbjct: 619 DSEEAPAAMTAAQAKPALKIPQTK-ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 677
Query: 934 SSPSPSRVTSRTTPRRSRSVSPCSNVE-SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992
SSP+ + T R S S S E + L + S +VK + P + G
Sbjct: 678 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 737
Query: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052
P + +T GP+++ K+ EK +DS S +++ P + V
Sbjct: 738 -GTAPVLPGKT--GPTVTQVKA----EKQEDS-----ESSEEESDSEEAAASPAQVKTSV 785
Query: 1053 SSLQLKGQ--SQTSPDHRSDTSSP-----EVRQSHSESPSLQSKSQTSPKGGRSRSSSPV 1105
Q K + +P + S+P Q+ SPS +P+ + P
Sbjct: 786 KKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPA 845
Query: 1106 TELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESK 1165
+ + S + P SG S E+S + ++ + V + Q R A +K
Sbjct: 846 S-VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK 904
Query: 1166 EKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ 1225
E P++ A +PP K P Q ++ +GSS E +
Sbjct: 905 ES----PRKGAAPTPP---GKTGPSAAQ----------------AGKQDDSGSSSEESDS 941
Query: 1226 NSALPTSSQDEELME----VVEKSEEPAG--------QILSHLSSELKEMSTSNFESSPE 1273
+ P + ++++ V+ + PAG Q S ST+ SS
Sbjct: 942 DGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSES 1001
Query: 1274 VEER--PAVSLTLDQSQSQASLEAVEVPSMA--SSWGGPHFSPEHKELSNSPLRENSFGS 1329
+E PA ++ P +A +S G S E +S+ +E
Sbjct: 1002 EDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ 1061
Query: 1330 PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPD 1389
+ P + +T ++ L P L +++ + S SSS D
Sbjct: 1062 VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEED 1121
Query: 1390 AVEKAGMSSNQSISSPVLDAVPRTPSR-ERSSSASSPEMKDGLPRTPSRRSRSG-SSPGL 1447
G S ++ TPSR E ++ E + PS+ SG +PGL
Sbjct: 1122 GEGPQGAKSAHTLGP--------TPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGL 1173
Query: 1448 RDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ------TPRPRSRSPS 1501
TP+ S ++P + P S ++ D + +A PQ +P+ + +
Sbjct: 1174 -----TPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAA 1228
Query: 1502 SPELNNKCLTPQRERSGSESS--VDQKTVARTPLGQ----RSRSGSSQELDVKPSASPQE 1555
S K P++ ++S Q + + LGQ + + V QE
Sbjct: 1229 SGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE 1288
Query: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615
R + + ++ R+R SG P + +P K K +
Sbjct: 1289 RKKVVDTTKESSRKGWESRKRKLSGDQP--------------AARTPRSKKKKKLGAGEG 1334
Query: 1616 SGSDSSPEPKAPAPRALPRRSR-SGSSSKGRGPSPEGSSSTESSPEHPPKS--RTARRGS 1672
+ SPE + + +R + SG + +G GS + PE + T G
Sbjct: 1335 GEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGD 1394
Query: 1673 RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
+S+P+ K + + +R+ + E +KA+ + S S S + + +
Sbjct: 1395 QSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKK 1441
Score = 107 bits (267), Expect = 2e-22
Identities = 287/1443 (19%), Positives = 524/1443 (36%), Gaps = 179/1443 (12%)
Query: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR--SESESKKRKHRSPTPKSKRKSKDKK 244
Q KK + D SESS E + + K R S + S + K K K++ +K
Sbjct: 72 QAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
Query: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
++ ++ P P + + ++ + +S +SA +TT + S
Sbjct: 132 AGKTGNSMPHP--------ATGKTVANLLSGKSPRKSAEPSANTTLV--------SETEE 175
Query: 305 EGDAP----FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
EG P ++PG S + S T S + D + K + +P+ S +
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSD-----ETDVEGKPSVKPAQVKASSVST 230
Query: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
E PA A G TP + PP++ R + P + E + S SE
Sbjct: 231 KESPARKAAPAPGKVGD-----VTPQVKGGALPPAK----RAKKPEEESESSEEGSESEE 281
Query: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGS-HREISSSPTSKN---RSHGRAKRDKSHSHT 476
P+ ++V APA G+ + + +P K S +A + + S +
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRR----- 531
S S A + +++ K + S ++ + R G + +P +
Sbjct: 342 SSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP---AKESPRKGAAPAPPGKTGPAV 398
Query: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR 591
++++ +R S+S + + + + + ++P R S PA+ + PA
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS---APAKESPRKGAAPAP 455
Query: 592 RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT 651
R + + + R S R + + + +SP + +
Sbjct: 456 PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG 515
Query: 652 PARRGRSRSRTPARRGRSRSRTPARRSGR----SRSRTPARRGRSRSRTPRR---GRSRS 704
P +G P G+ TP+ + G+ S S + S P + +S
Sbjct: 516 PLGKGAG----PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS 571
Query: 705 RSLVRRGRSHSR----TPQRRGRSG---SSSERKNKSRTSQRRSRSNSSPEMKKSRISSR 757
+ + + S PQ+ G + + + S +S+ S S S E + +++
Sbjct: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 631
Query: 758 RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR-----SRSGSSQPKAKSRTPP 812
+L P++KA + + + + + P + PR+ S +GSS A P
Sbjct: 632 AKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 689
Query: 813 RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK---VKSGTPPRQGSI---TSPQANEQSVT 866
SSS ++ KT + + K VK+ + P +GS+ T+P ++
Sbjct: 690 AEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP 749
Query: 867 PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS---TPPRQSPSRSSSPQPK----- 918
+ E D E S S + +SP +VK+S T + +P+ + +P K
Sbjct: 750 TVTQVKAEKQEDSE-SSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 808
Query: 919 ----VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV-----SPCSNVESRLLPRYSH 969
V A +QRS S P + S R SV + + +++ P
Sbjct: 809 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE-ED 867
Query: 970 SGSSSPDTKVKPET-------PPRQSHSGSISPYP------KVKAQTPPGPSLSGSKSPC 1016
SGSS ++ + E P ++H + P K A TPPG + +
Sbjct: 868 SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 927
Query: 1017 PQEKSKDSLVQS-----CPGSLSLCAGVKSS---TPPGESYFGVSSLQLKGQSQTSP-DH 1067
Q+ S S +S P +++ +K P S G ++ + Q+ ++P
Sbjct: 928 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKA 987
Query: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA--SP 1125
R+ S+ S SE + +Q G R+ + T +P G S+ S
Sbjct: 988 RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS 1047
Query: 1126 MLKSGMSPEQSRFQSDSS--SYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183
+ G E Q DS+ + P S Q++ K K LP + AT +P
Sbjct: 1048 RISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPK--LPEVQQATKAPESS 1105
Query: 1184 KDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELME--V 1241
D +D +SS E G G K ++ PT S+ E L+E
Sbjct: 1106 DDS------EDSSDSS---------SGSEEDGEGPQ-GAKSAHTLGPTPSRTETLVEETA 1149
Query: 1242 VEKSEE----PAGQILS-HLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAV 1296
E SE+ P+ +LS +++ L ++ +++P+++ P+VS TL +
Sbjct: 1150 AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1209
Query: 1297 EVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN 1356
+ P A+ P + +P + P + + T S + + L
Sbjct: 1210 K-PQQAAGMLSPKTGGKEAASGTTPQKSR---KPKKGAGNPQAST---LALQSNITQCLL 1262
Query: 1357 G-PF-LNQLETDPSL-----DMKEQSTRSSGHSSSELSPDAVE--KAGMSSNQ-SISSPV 1406
G P+ LN+ + S+ ++ EQ + ++ E S E K +S +Q + +P
Sbjct: 1263 GQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPR 1322
Query: 1407 LDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGM 1466
+ + E ++ SPE + ++R ++ + G G S S G
Sbjct: 1323 SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKG-------SLGSQGA 1375
Query: 1467 KDIPR---TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSV 1523
KD P G E PK+ + + R + K + SES
Sbjct: 1376 KDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1435
Query: 1524 DQK 1526
+K
Sbjct: 1436 QKK 1438
Score = 105 bits (261), Expect = 8e-22
Identities = 243/1320 (18%), Positives = 465/1320 (35%), Gaps = 208/1320 (15%)
Query: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
G+ TPQ +G G+ K + + S E ++ + RS+ KA
Sbjct: 243 GKVGDVTPQVKG--GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV------KAS 294
Query: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
++ R+ S + K TP ++G+ + K+ P S SSS + +TP
Sbjct: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 831 --------------SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
S+ +S+ + G P T P + + SS
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSS 414
Query: 877 PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP 936
+ + + P++ SG +P +S P ++SP + ++P P PR+ + P
Sbjct: 415 EESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAP-------PRK------TGP 461
Query: 937 SPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996
+ ++V SRS S S+ + L ++ +VKP +
Sbjct: 462 AAAQVQVGKQEEDSRSSSEESDSDREAL-------AAMNAAQVKP-----------LGKS 503
Query: 997 PKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQ 1056
P+VK + G G L AG PPG+ S Q
Sbjct: 504 PQVKPASTMG-----------------------MGPLGKGAG---PVPPGKVGPATPSAQ 537
Query: 1057 L---KGQSQTSPDHRSDTSSPEV------RQSHSESPSLQSKSQTSPKGGRSRSSSPVTE 1107
+ + S++S + SD+S EV Q S LQ+K +SP G + + PV
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
Query: 1108 LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEK 1167
+ A + + S E+S +DS P + + A++K
Sbjct: 598 ------------QVKAEKPMDNSESSEESSDSADSEEAP----------AAMTAAQAKPA 635
Query: 1168 MALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSG--AGSSPETKEQ 1225
+ +P A P + S R + K T P S AG + E
Sbjct: 636 LKIP---QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Query: 1226 NSALPTSSQDEEL--MEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLT 1283
+S+ S +EE + V + G+ L ++ + + ++P + + ++T
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 1284 LDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEM 1343
+++ Q E+ E S + SP ++ S + + +P R GT
Sbjct: 753 QVKAEKQEDSESSEEESDSEEAAA---SP--AQVKTSVKKTQAKANPAAARAPSAKGTIS 807
Query: 1344 NTG------------FSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAV 1391
G S+VK + P + + + + + ++ P+
Sbjct: 808 APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE-- 865
Query: 1392 EKAGMSSNQSISSPVLDAVPRT-PS------RERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
E +G S +S S + + + PS R + A K P P + S +
Sbjct: 866 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 925
Query: 1445 PGLRDGSGTPSRHSLS-GSSPGMKDIPRT---------PSRGRSECDSSPEPKALPQTPR 1494
G +D SG+ S S S G +P + P+R + ++P TPR
Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
Query: 1495 PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQ 1554
S S+ RS S S D+ + P Q G + P+A P+
Sbjct: 986 KARASEST------------ARSSSSESEDEDVI---PATQCLTPGIRTNVVTMPTAHPR 1030
Query: 1555 ERSESDSSPDSKAKTRTPLRQ-RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR-AAP 1612
++ + S +K + + + + G + +VDS P S +S + K + P
Sbjct: 1031 IAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1090
Query: 1613 RAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT--ARR 1670
+ ++ P++ S SGS G G P+G+ S + P ++ T
Sbjct: 1091 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEG--PQGAKSAHTLGPTPSRTETLVEET 1148
Query: 1671 GSRSSPEP------------KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718
+ SS + T TP ++S+++P+L +S + +A P+ +
Sbjct: 1149 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVS-STLAAKDDPDGKQ 1207
Query: 1719 RTPPRHRR---SPSVSSPEPAE---KSRSSRRRRSASSPRTKTTSRRGRSPS---PKPRG 1769
P+ SP E A +S + ++ A +P+ T + + +P
Sbjct: 1208 EAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWP 1267
Query: 1770 LQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQE 1829
L ++ ++ K T T++ R SR +R+ G +R+P ++
Sbjct: 1268 LNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESR--KRKLSGDQPAARTPRSKK 1325
Query: 1830 SSRTSSRRRRGRS----RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR 1885
+ + S +T TS+ +++ + K + + S + + +
Sbjct: 1326 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1385
Query: 1886 RRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR------SRTPPVTRRRSRSRT 1939
S +S+ + +R + + +++++ S +P +++ + +T
Sbjct: 1386 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1445
Score = 101 bits (252), Expect = 9e-21
Identities = 255/1353 (18%), Positives = 454/1353 (33%), Gaps = 222/1353 (16%)
Query: 892 SGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS------RVTSRT 945
+ + PR+ S+ SS + K KA + +G+S P P+ + S
Sbjct: 98 TAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMPHPATGKTVANLLSGK 155
Query: 946 TPRRSRSVSPCSNVESRL-----LPRY--------------------SHSGSSSPDTKVK 980
+PR+S S + + S +P + + S S D + K
Sbjct: 156 SPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGK 215
Query: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSP--------------CPQEKSKDSLV 1026
P P Q + S+S + P P G +P P+E+S+ S
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS-E 274
Query: 1027 QSCPGSLSLCAGVKSSTPPGESYFGV--SSLQLKG-----------------QSQT---S 1064
+ AG +S E V +S KG SQT
Sbjct: 275 EGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGK 334
Query: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
P+ S++SS E S E+P+ ++ Q +++S +++ + S ++ A+
Sbjct: 335 PEEDSESSSEESSDSEEETPAAKALLQ-------AKASGKTSQVGAASAPAKESPRKGAA 387
Query: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK 1184
P P ++ Q+ + QS E ++S+E+ P Q + P+ +
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDS--------QSSSEESDSEEE--APAQAKPSGKAPQVR 437
Query: 1185 DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ----NSALPTSSQDEELME 1240
+P R K PPR+ A + + +Q S+ S D E +
Sbjct: 438 AASAPAKESPR-------KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
Query: 1241 VVEKSE-EPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299
+ ++ +P G+ S ++K ST + P + + A + E
Sbjct: 491 AMNAAQVKPLGK-----SPQVKPASTMGMGPLGK-GAGPVPPGKVGPATPSAQVGKWEED 544
Query: 1300 SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
S +SS S + +P +E S G+ L+ + T ++ GP
Sbjct: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK---------PTSSPAKGPPQKAGPV 595
Query: 1360 LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS 1419
Q++ + +D E S SS + SE +P A+ A + ++ P A P+ + S
Sbjct: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA--QAKPALKIPQTKACPKKTNTTAS 653
Query: 1420 SSASSPEMKDGLPR-TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD--------IP 1470
+ + + PR + S +GSSP + G+ P+ S S ++ +
Sbjct: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
Query: 1471 RTPSRGRS---ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527
+ S G+ + S P +L Q P + P + Q + SE D +
Sbjct: 714 QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEE 773
Query: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
A +P ++ +Q +A + S+P +QRS S P V +
Sbjct: 774 AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN 833
Query: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSG-----------SDSSPEPKAPA---PRALP 1633
+ S P V A +AQ+G SDS E + A P
Sbjct: 834 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKT 893
Query: 1634 RRSRSG------SSSKGRGPSP----------------EGSSSTESSPEHPPKSRTARRG 1671
+ R+ S KG P+P GSSS ES + +
Sbjct: 894 HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Query: 1672 SRSSP----EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS--------PETRSR 1719
P +P P + + RKAR S + +SSS P T+
Sbjct: 954 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL 1013
Query: 1720 T----------PPRHRRSPSVSSPEPAEKSRSSRR---RRSASSPRTKTTSRRGRSPSPK 1766
T P H R +S A S+ S R + P T+ S G P+
Sbjct: 1014 TPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATS 1073
Query: 1767 PRGLQ-RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR-- 1823
P+ +++ ++ K + + + + +S+ S S S G G S
Sbjct: 1074 PQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT 1133
Query: 1824 ---SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRT 1880
+P+R E+ + S+ +P +PA + S++ T
Sbjct: 1134 LGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG--------LTPANSQASKA-T 1184
Query: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
P + S S T + + ++ + + + + S T P R+ +
Sbjct: 1185 PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAG 1244
Query: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
+ + + +T+ P + S +T + R V + SR
Sbjct: 1245 NPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGW 1304
Query: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPR 2060
+R+R S P +RTP +K+ S +T
Sbjct: 1305 ESRKRKLSGDQPA------------------ARTPRSKKKKKLGAGEGGEASVSPEKTST 1346
Query: 2061 TARGKRSLTRSPPAIRRRSASGSSSDRSRSATP 2093
T++GK ++ ++ + GS + P
Sbjct: 1347 TSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1379
Score = 100 bits (248), Expect = 3e-20
Identities = 258/1312 (19%), Positives = 475/1312 (36%), Gaps = 178/1312 (13%)
Query: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKK----DRGRRSESSSP---RRERKKS 212
A++ AP P K + + P K+ KK +++ + G SE +P R + K S
Sbjct: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
Query: 213 SKKKKHRSESESKKR---KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
K + R+ S K K +P P K + S T A K S+S +S+
Sbjct: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAV-------ASQTKAGKPEEDSESSSEESS 347
Query: 270 SSSD-TSRSRSRSAAAKTHTTALAGRSPSPA--SGRRGEGDAP---------FSEPGTTS 317
S + T +++ A + T+ G + +PA S R+G AP ++ G
Sbjct: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
Query: 318 TQRPSSPETATKQPSSPYEDKDKDK--KEKSATRPSPSPERSSTGPEPPAPT-PLLAERH 374
SS E + + +P + K K + ++A+ P+ R P PP T P A+
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPP--KSPEKLPQSSS-----SESSPPSPQP 427
G + + + + + + A+ + P KSP+ P S+ + + P P P
Sbjct: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP-P 526
Query: 428 TKVSRHASSSPESPKPAPAPGSHREISSS-----PT----SKNRSHGRAKRDKSHSHTPS 478
KV S+ + S E S S PT ++ +S G + K S +P+
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-SPA 585
Query: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
+ + P + ++ P S S S A + Q + + PQ
Sbjct: 586 KGPPQKAGPVAV---QVKAEKPMDNSESSEESSDSADSEEAP--AAMTAAQAKPALKIPQ 640
Query: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
+ NT + R G R T +PA G ++ PA S S
Sbjct: 641 TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG--GTQRPAEDSSSSEE 698
Query: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR-RRSRSRSPARRSGRSRSRTPARRGR 657
++ G+++S + PV+ + +P P + G
Sbjct: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV---------LPGKTGP 749
Query: 658 SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
+ ++ A + + + +PA+ S +T + + +R
Sbjct: 750 TVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA----------ARA 799
Query: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
P +G + + + +++RS S P ++ + S+ +R +S S
Sbjct: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS---------- 849
Query: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
G + ++QT P SGSS+ ++ S + + + P K+ +
Sbjct: 850 --VGKAVATAAQAQTGPEED-SGSSEEESDSE---EEAETLAQVKPSGKTHQIRAALAPA 903
Query: 838 SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897
K + TPP + ++ QA +Q SGSS
Sbjct: 904 KESPRKGAAPTPPGKTGPSAAQAGKQ--------------------------DDSGSSS- 936
Query: 898 RVKSSTPPRQSPSRSSSPQP-KVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPC 956
+ S ++P+ +S Q K I RS +G ++ +P++ + +TPR++R+
Sbjct: 937 --EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA-TPAQAQAASTPRKARASEST 993
Query: 957 SNVESRLLPRYSHSGSSSPDTKVKPETP-PRQSHSGSISPYPKVKAQTPPGPSLSGSKSP 1015
+ S S S D V P T ++ P + P S++G+ S
Sbjct: 994 AR----------SSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSS 1043
Query: 1016 CPQEKSKDSLVQSCPGS-LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS----PDHRSD 1070
+ D Q P + + G +T P +S+Q KG ++ P+ +
Sbjct: 1044 KESSRISDGKKQEGPATQVDSAVGTLPATSPQS-----TSVQAKGTNKLRKPKLPEVQQA 1098
Query: 1071 TSSPEVRQSHSESPSLQSKSQ---TSPKGGRSRSSSPVTELASRSPIRQDRGEFS----- 1122
T +PE +S S S+ P+G +S + T + + + + E S
Sbjct: 1099 TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVV 1158
Query: 1123 --ASPMLKSGMSPEQSRFQSDSS-SYPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179
+ +L M+P + S +S + P +DS+ + + + K PQ+ A
Sbjct: 1159 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1218
Query: 1180 PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELM 1239
P+ K + P+ S R P + +S + N Q L
Sbjct: 1219 SPKTGGKEAASGT--TPQKS-------RKPKKGAGNPQASTLALQSNITQCLLGQPWPLN 1269
Query: 1240 EVVEKSEEPAGQILSH-LSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEV 1298
E + + ++L+ L E K++ + ESS + E L+ DQ ++ +
Sbjct: 1270 EA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKK 1327
Query: 1299 PSMASSWGGPHFSPEHKELSN--SPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN 1356
A G SPE ++ R+ + G E + G LG++ G E +E+L
Sbjct: 1328 KLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---GAKDEPEEELQ 1384
Query: 1357 ---GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP 1405
G +++P K++ +S + + +KA +S + SP
Sbjct: 1385 KGMGTVEGGDQSNPK--SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP 1434
Score = 96.3 bits (238), Expect = 4e-19
Identities = 263/1433 (18%), Positives = 487/1433 (33%), Gaps = 198/1433 (13%)
Query: 1343 MNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS--ELSPDAVEKAGMSSNQ 1400
++T SSE +E+ + P L S + SS E + EKAG + N
Sbjct: 82 ISTSESSEEEEEAEA---ETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGN- 137
Query: 1401 SISSPVLDAVP------RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
S+ P ++P + SA++ + + + + PG+
Sbjct: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
Query: 1455 SRHSLSGSSPGMKDIPRTPS----RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCL 1510
S + SS D+ PS + ++ S+ E A P P +P++ L
Sbjct: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGAL 257
Query: 1511 TPQR-----ERSGSESSVDQKTVARTPLGQRSRSGSSQE-LDVKPSASPQERSESDSSPD 1564
P + E S ++ P G RS+ +S++ L V+ +++P + + +
Sbjct: 258 PPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
Query: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
+ + ++++G PE DS+S S S E +A +A++ +S
Sbjct: 318 APPGKAGAVASQTKAGK-PEEDSESS----SEESSDSEEETPAAKALLQAKASGKTSQVG 372
Query: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR------SSPEP 1678
A AP S KG P+P G + P A+ G R SS E
Sbjct: 373 AASAPA-------KESPRKGAAPAPPGKTG--------PAVAKAQAGKREEDSQSSSEES 417
Query: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR-------HRRSPSVS 1731
++ P + + S +P++ + ++ S ++P +T P + S S
Sbjct: 418 DSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS 477
Query: 1732 SPEPAEKSRSSRRRRSAS-------SPRTKTTSRRGRSP-----SPKPRGLQRSRSRSRR 1779
S E ++ R + +A+ SP+ K S G P P P G + S +
Sbjct: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 1780 -------EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR 1832
++ + D S T+ + +S + + + + SPA+ +
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKP------TSSPAKGPPQK 591
Query: 1833 TSSRRRRGRSRTPPTSRKRSRSRTSPA-----PWKRSRSRASPATHRRSRSRTPLISRRR 1887
+ ++ P + + S + A P + ++A PA P +
Sbjct: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT 651
Query: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947
+ ++ +PV R T R+ + + S T S S +
Sbjct: 652 ASAKVAPV-----RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 1948 SRTPPVTRRRS-------RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
V + +S ++ + PV + + + + T ++ S +S
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 2001 VTRRRSRSRTSPVTRRRSRSRT-----PPAIRRRSRSRTPLLPRK------RSRSRSPLA 2049
+ SP + S +T P A R S T P K +++ RSP
Sbjct: 767 EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSK 826
Query: 2050 IRRRSRSRTPRT--ARGKRSLTRSPPAIRRRSA--------SGSSSDRSRSATPPAT--R 2097
++ R+ T ARG S+ A+ + SGSS + S S T +
Sbjct: 827 VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Query: 2098 NHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMM 2157
+T + + R +PTP PG P + QAG
Sbjct: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTP------PGKTGPSAA---------QAGKQ-- 929
Query: 2158 DGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP-----PSMSAAGLAARMSQVP 2212
D +S E+ + A+T+ + +PP P+ S AG AA +Q
Sbjct: 930 --------DDSGSSSEESDSDGEAPAAVTSAQV--IKPPLIFVDPNRSPAGPAATPAQAQ 979
Query: 2213 APVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLAS 2272
A R + + +S + + TP I T V + P A ++A
Sbjct: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
Query: 2273 PRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALA-ALSLTGSGTPPT----------AA 2321
++ S ++ + A V+ A PA + S+ GT A
Sbjct: 1040 ASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQAT 1099
Query: 2322 NYPSSS-----------------RTPQAPASANLVGPRSAHATAPVNIAGSRTAA--ALA 2362
P SS PQ SA+ +GP + V + ++ +A
Sbjct: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVA 1159
Query: 2363 PA-SLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTS 2421
P+ SL S M P L+ AN + + S ++ D + + M S
Sbjct: 1160 PSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLS 1219
Query: 2422 ERAPSPSSRMGQAPSQSLLPP-AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480
+ + G P +S P P++ + S+ ++CL+ Q P+ +Q +S
Sbjct: 1220 PKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVK 1279
Query: 2481 ATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSS 2540
T + ++ +G QP+A K++ + +S
Sbjct: 1280 VLTELLEQERKKVVDTTKESSRKGWESRKRKLSG-DQPAARTPRSKKKKKLGAGEGGEAS 1338
Query: 2541 SSSSSSSSSSSSSSSSGSSSSD-----------SEGSSLPVQPEVALKRVPSPTPAPKEA 2589
S +S++S + +S D S+G+ +PE L++ ++
Sbjct: 1339 VSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK--DEPEEELQKGMGTVEGGDQS 1396
Query: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
+ + + KRK+ + +S+ S S S ++ +
Sbjct: 1397 NPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1449
Score = 94.4 bits (233), Expect = 1e-18
Identities = 263/1450 (18%), Positives = 503/1450 (34%), Gaps = 165/1450 (11%)
Query: 1364 ETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSAS 1423
E D +L K+ TR S S+ S + E+A + A PR S S +
Sbjct: 66 EEDAALQAKK--TRVSDPISTSESSEEEEEA--------EAETAKATPRLASTNSSVLGA 115
Query: 1424 S--PEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECD 1481
MK+ + ++G+S +G + LSG SP P + SE +
Sbjct: 116 DLPSSMKEKAKAETEKAGKTGNSMP-HPATGKTVANLLSGKSPRKSAEPSANTTLVSETE 174
Query: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541
A +P S + +++ S E+ V+ K + P ++ S S
Sbjct: 175 EEGSVPAFGAAAKPGMVSAGQADSSSE----DTSSSSDETDVEGKPSVK-PAQVKASSVS 229
Query: 1542 SQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSS 1601
++E + A+P D +P K P ++ + E + S + +G+
Sbjct: 230 TKESPAR-KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
Query: 1602 PEVKDKPR--------AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
+VK + A + G ++P P A + S E S
Sbjct: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
Query: 1654 STESSP------EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
S E +P + +T++ G+ S+P ++ + ++ P + + R
Sbjct: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE 408
Query: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767
S SSS E+ S + PS +P+ R+AS+P K + R+G +P+P
Sbjct: 409 DSQSSSEESDSEEEAPAQAKPSGKAPQV----------RAASAP-AKESPRKGAAPAPPR 457
Query: 1768 R----------GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG- 1816
+ G Q SRS E++ + R + ++ + ++ + +S G
Sbjct: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDRE---ALAAMNAAQVKPLGKSPQVKPASTMGM 514
Query: 1817 ---GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATH 1873
G G P + + S++ + + +S + S S P + +PA
Sbjct: 515 GPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVP-----TAVAPA-Q 568
Query: 1874 RRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933
+S S ++ P + + S +S S + S P
Sbjct: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 628
Query: 1934 RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV-----TRRRSRSRTSPI---------TR 1979
++++ P + P T + ++ PV R++ + TSP T+
Sbjct: 629 AAQAK-PALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQ 687
Query: 1980 RRSRSRTSPVTRRRSRSRTS-PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLP 2038
R + +S +T VT +++S + + ++ + P + P+LP
Sbjct: 688 RPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL---QVKAASVPVKGSLGQGTAPVLP 744
Query: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
K + + + ++ S + SP ++ S A P A R
Sbjct: 745 GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT-----SVKKTQAKANPAAARA 799
Query: 2099 HSGSRT---PPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGS 2155
S T P + ++ + PS P+ ++ +L +S +
Sbjct: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 859
Query: 2156 MMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV 2215
GP + S E A++ LA S T + +++ A + R P P
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAET---LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
Query: 2216 PLMSLRTAP-AANLASRIPAASAAAMNLASARTPAIPTAVNLAD--------SRTPAAAA 2266
+T P AA + + S++ + + PA T+ + +R+PA A
Sbjct: 917 G----KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
Query: 2267 AMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSS 2326
A +P A A S A TA + + A LT G P++
Sbjct: 973 A----TPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLT-PGIRTNVVTMPTA 1027
Query: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSR--------TAAALAPASLTSARMAPALSGA 2378
P+ A++ G S+ ++ ++ + +A PA+ + A
Sbjct: 1028 H--PRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTN 1085
Query: 2379 NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS 2438
L P++P E +P D + + S+ S+ + + +G PS++
Sbjct: 1086 KLRKPKLP----EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRT 1141
Query: 2439 LLPPAQDQPRSPVPSAFSDQSRCLIAQTTP---VAGSQSL-------SSGAVATTTSSAG 2488
+ S + L TP A SQ+ SS +V++T ++
Sbjct: 1142 ETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKD 1201
Query: 2489 DHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSS 2548
D +G P G TG ++ A + P K R+ + + +S+ + S
Sbjct: 1202 DPDGKQEAK----PQQAAGMLSPKTGGKE--AASGTTPQKSRKPKKGAGNPQASTLALQS 1255
Query: 2549 SSSSSSSSGS---SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREG-----------R 2594
+ + + + + S + V E+ + KE+ R+G +
Sbjct: 1256 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1315
Query: 2595 PPEPTP--AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
P TP K+K+ + +S S +S++S + +S S A
Sbjct: 1316 PAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGA 1375
Query: 2653 KPGP-QALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711
K P + L K + G +S K D R E+++ + + S +D +
Sbjct: 1376 KDEPEEELQKGMGTVE---GGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSE 1432
Query: 2712 SSSSERGSRR 2721
S S ++ ++
Sbjct: 1433 SPSQKKKKKK 1442
Score = 91.3 bits (225), Expect = 1e-17
Identities = 247/1302 (18%), Positives = 460/1302 (35%), Gaps = 188/1302 (14%)
Query: 1514 RERSGSESSVDQ--KTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSS------PDS 1565
R+R E + Q KT P+ S +E + + + + + ++SS P S
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 1566 -KAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
K K + + ++G+S + + + SG SP + A P A + S E
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGK-TVANLLSGKSP----RKSAEPSANTTLVSETEE 175
Query: 1625 KAPAPRALPRRSRSGSSSKGRGPSPE---GSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681
+ P A ++ G S G+ S SSS E+ E P + A+ + S ++
Sbjct: 176 EGSVP-AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESP 234
Query: 1682 SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS 1741
+R +++P + ++ + + + P R++ P S S E
Sbjct: 235 AR--------KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
Query: 1742 SRRR----------RSASSPRTKTTSRRGRSPSPKPR-GLQRSRSRSRR-EKTRTTRRRD 1789
+R + R+AS+P K T +G +P+P + G S++++ + E+ + +
Sbjct: 287 TRSQVKASEKILQVRAASAP-AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE 345
Query: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ--------ESSRTSSRRRRGR 1841
S S + T + ++++ + G + ++ R+ ++ ++ + G+
Sbjct: 346 SSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK 405
Query: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSR 1901
S AP + S +P R+ S S R+ + P +
Sbjct: 406 REEDSQSSSEESDSEEEAPAQAKPSGKAPQV--RAASAPAKESPRKGAAPAPPRKTGPAA 463
Query: 1902 SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR--SRTPTTRRRSRSRTPPVTRRRSR 1959
++ V ++ SR+S R + + + ++P + S P+ +
Sbjct: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGK--GA 521
Query: 1960 SRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2019
PP + P T ++ V + S +S S P ++
Sbjct: 522 GPVPP-------GKVGPATP------SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 568
Query: 2020 SRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSR-----SRTPRTARGKRSLTRSPPA 2074
++ I + + +P + + P+A++ ++ S + + +P A
Sbjct: 569 EKSLGNILQAKPTSSPA--KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 626
Query: 2075 IRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPG 2134
+ A + A P T + ++ PV + + +P SP
Sbjct: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQ----------APRKAGTATSP- 675
Query: 2135 MLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS-RIALALTAISLGTA 2193
AG S G + P +S E+ ++ + LA+T +
Sbjct: 676 -----------------AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSV 718
Query: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANL--ASRIPAASAAAMNLASARTPAIP 2251
+ AA + + S P++ +T P A + + ++ S A P
Sbjct: 719 GKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSL 2311
V + +T A A +P A APSA T +AP G AA A
Sbjct: 779 AQVKTSVKKTQAKA------NPAAARAPSAKG-----TISAP-----GKVVTAAAQAKQR 822
Query: 2312 TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA----TAPVNIAGSRTAAALAPASL- 2366
+ S P N +S+ + PAS VG A A T P +GS + +
Sbjct: 823 SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAE 882
Query: 2367 TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426
T A++ P+ + + P R +PP +T PSA + + S
Sbjct: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP------GKTGPSAAQAGKQDDSGSSS 936
Query: 2427 PSSRM-GQAPS-----QSLLPPA--QDQPRSPV-PSAFSDQSRCLIAQTTPVAGSQSLSS 2477
S G+AP+ Q + PP D RSP P+A Q++ A +TP S S+
Sbjct: 937 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ---AASTPRKARASEST 993
Query: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537
+++ S D PG+ + V P+A + P
Sbjct: 994 ARSSSSESEDEDVIPATQCLTPGIRTNVV---------TMPTAHPRIAP----------- 1033
Query: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597
+S + +SSS SS S EG + V V SP +A + +
Sbjct: 1034 ----KASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRK 1089
Query: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--------------SSSS 2643
P + ++ + + SS S SS SSS S + S+ ++
Sbjct: 1090 PKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETA 1149
Query: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
+ SS P L +P P + S++ K L S S+S + + P
Sbjct: 1150 AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPK----LDSSPSVSSTLAAKDDPDG 1205
Query: 2704 QPSPRDQQSS---SSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
+ + QQ++ S + G + G + S K ++ +P+
Sbjct: 1206 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQ 1247
Score = 71.6 bits (174), Expect = 1e-11
Identities = 121/513 (23%), Positives = 191/513 (37%), Gaps = 66/513 (12%)
Query: 2214 PVPLMSLRT--APAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271
PV L+ + T + L + A AA+ R + P + + + A A A
Sbjct: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRV-SDPISTSESSEEEEEAEAETAKA 101
Query: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSS---R 2328
+PR A S+V AD P++ A S+ T T AN S +
Sbjct: 102 TPRLASTNSSVLGAD--LPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRK 159
Query: 2329 TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLS 2388
+ + A+ LV + P A A + SA A + S +S S
Sbjct: 160 SAEPSANTTLVSETEEEGSVPA-------FGAAAKPGMVSAGQADSSSEDTSSS-----S 207
Query: 2389 AYERVSGRTS-PPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ---SLLPPAQ 2444
V G+ S P +A S + +P++ + AP+P ++G Q LPPA+
Sbjct: 208 DETDVEGKPSVKPAQVKASSVSTKESPAR-----KAAPAPG-KVGDVTPQVKGGALPPAK 261
Query: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
R+ P S+ S GS+S A A T S +L V A P
Sbjct: 262 ---RAKKPEEESESSE---------EGSES-EEEAPAGTRSQVKASEKILQVRAASAPAK 308
Query: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
G P P A+ + S SSS SS S + ++ + + S
Sbjct: 309 --GTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 366
Query: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
+S +V + + KE+ R+G P P P K + + + S SSS
Sbjct: 367 KTS----------QVGAASAPAKESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSE 415
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG---------ERRS 2675
S S + + + S + ++ +PAK P+ PA P+K P E S
Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
Query: 2676 RSPRKPIDSLRDS-RSLSYSPVERRRPSPQPSP 2707
RS + DS R++ +++ + V+ SPQ P
Sbjct: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Score = 70.1 bits (170), Expect = 3e-11
Identities = 104/464 (22%), Positives = 164/464 (35%), Gaps = 44/464 (9%)
Query: 2264 AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
AA + S + V L D T L R AAL + +
Sbjct: 26 AAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTS 85
Query: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
SS +A A PR A + V A P+S+ A A T
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSV-------LGADLPSSMKEKAKAET-EKAGKTGN 137
Query: 2384 RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS-SRMGQAPSQSLLPP 2442
+P A +G+T LL R + + + SE S G A ++
Sbjct: 138 SMPHPA----TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSA 193
Query: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Q S S+ SD+ T V G S+ V ++ S + + PAPG
Sbjct: 194 GQADSSSEDTSSSSDE--------TDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG-- 243
Query: 2503 HSDVGE-PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
VG+ P G P A A +P +E S SS S S + + + S +
Sbjct: 244 --KVGDVTPQVKGGALPPAKRAKKPEEE---SESSEEGSESEEEAPAGTRSQVKASEKIL 298
Query: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621
+S P + P+P P AV A + + S SSS SS
Sbjct: 299 QVRAASAPAKGTPGKGATPAP-PGKAGAV----------ASQTKAGKPEEDSESSSEESS 347
Query: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
S + ++ + + +S +S ++ +PAK P+ PA P K P ++++ ++
Sbjct: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
Query: 2682 ID---SLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG 2722
D S +S S +P + + P R S+ ++ R+G
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVR-AASAPAKESPRKG 450
Score = 64.7 bits (156), Expect = 1e-09
Identities = 156/764 (20%), Positives = 250/764 (32%), Gaps = 119/764 (15%)
Query: 2072 PPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTP----- 2126
P + A SS D S S+ + P + +S +S P+ P
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEGKPSVK--PAQVKASSVSTKESPARKAAPAPGKV 245
Query: 2127 --LDRCRSPGMLEPLGSSRTPMSVLQQAG-GSMMDGPGPRIPDHQRTSVPENHAQSRIAL 2183
+ G L P ++ P + + GS + P + E Q R A
Sbjct: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPA-GTRSQVKASEKILQVRAAS 304
Query: 2184 ALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLA 2243
A + G P AG A ++ P + +++ PAA A A
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
Query: 2244 SARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGA--- 2300
S +T + AA+A SPR AP+ P T PAV A A
Sbjct: 365 SGKTSQV------------GAASAPAKESPRKGAAPA------PPGKTGPAVAKAQAGKR 406
Query: 2301 ------------RTPAALAALSLTGSGTPPTAANYPS--SSRTPQAPASANLVGPRSAHA 2346
A A +G AA+ P+ S R APA GP +A
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
Query: 2347 TAPVNIAGSRTAA--------ALAPASLTSAR---------------MAPALSGANLT-- 2381
SR+++ ALA + + M P GA
Sbjct: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 2382 ------SPRVPLSAYERVSGRTSPPLLDRARSRTPPS-APSQSRM---------TSERAP 2425
+P + +E S +S D + P + AP+Q + TS A
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK 586
Query: 2426 SPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV----- 2480
P + G Q D S S+ S S A T +L
Sbjct: 587 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646
Query: 2481 -ATTTSSAGDHNGMLSVPAP---GVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536
TT+SA + AP G S G PA G Q +PA++ SSSS
Sbjct: 647 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQ-------RPAED--SSSSE 697
Query: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPP 2596
S S + + + + S + +S+PV+ + AP + G
Sbjct: 698 ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSL------GQGTAPVLPGKTGPTV 751
Query: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG- 2655
A+++ S SS S S +++S + +S + + ++ +++ + S+ + + PG
Sbjct: 752 TQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGK 811
Query: 2656 ---PQALPKPASPKKPPPGERRSRS----PRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708
A K SP K P R ++ R P ++++ + + P
Sbjct: 812 VVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSS 871
Query: 2709 DQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
+++S S E Q S R P+ R ++ +P
Sbjct: 872 EEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
Score = 61.6 bits (148), Expect = 1e-08
Identities = 128/703 (18%), Positives = 233/703 (33%), Gaps = 94/703 (13%)
Query: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK 216
A +AKQ +P KP ++S+ + P K + P E S ++
Sbjct: 816 AAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP--EEDSGSSEE 873
Query: 217 KHRSESESKKRKHRSPTPKSKR------KSKDKKRKRSRSTTPAPKSRRAHRSTSAD-SA 269
+ SE E++ P+ K+ + +K+ RK + T P A ++ D S
Sbjct: 874 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG 933
Query: 270 SSSDTSRSRSRSAAAKTHTTALAGRSP----SPASGRRGEGDAPFSEPGTTSTQRPSSPE 325
SSS+ S S + AA T + + P P G P ++ ++ + E
Sbjct: 934 SSSEESDSDGEAPAAVTSAQVI--KPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASE 991
Query: 326 TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTP 385
+ + SS ED+D + T P + P P +A +
Sbjct: 992 STARSSSSESEDEDVIPATQCLT-----PGIRTNVVTMPTAHPRIAPK------------ 1034
Query: 386 LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPK--- 442
S + E+S D + P S+ SPQ T V ++ PK
Sbjct: 1035 ASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPE 1094
Query: 443 -----PAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRS---PATAKRGR 494
AP E SS +S + G + +HT R+ + A+
Sbjct: 1095 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSE 1154
Query: 495 SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR---SPQRRGRSRSPQRPGWSRSRNTQRR 551
P++ S +P + S + SP + P + Q+
Sbjct: 1155 DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA 1214
Query: 552 GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPAR 611
S + G + S T +SR P + + T + T
Sbjct: 1215 AGMLSPKTGGKEAASGTTP-------------QKSRKPKKGAGNPQASTLALQSNITQCL 1261
Query: 612 RGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRS 671
G+ P S V+ + R+ ++ +R+G + + +
Sbjct: 1262 LGQP---WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAA 1318
Query: 672 RTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERK 731
RTP + + + A G S +P + + S+ +R ++ SG E+K
Sbjct: 1319 RTPR---SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKA----------SGDVKEKK 1365
Query: 732 NKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQ 791
K + ++ E++K + + S+P+SK K+K +
Sbjct: 1366 GKGSLGSQGAKDEPEEELQKG-MGTVEGGDQSNPKSK------------------KEKKK 1406
Query: 792 TPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
+ R+ + K K++ + S S K+K K + Q+
Sbjct: 1407 SDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1449
Score = 52.0 bits (123), Expect = 8e-06
Identities = 62/279 (22%), Positives = 114/279 (40%), Gaps = 45/279 (16%)
Query: 111 TPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
TPG PA ++ K +L ++ +S + + DP + Q A P
Sbjct: 1170 TPGLTPANSQA-------SKATPKLDSSPSVSSTLA--AKDDPDGKQEAKPQQAAGMLSP 1220
Query: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSS---------------PRRERKKSSKK 215
+ +E++S +P QK +K KK G S+ P E + +
Sbjct: 1221 KTGGKEAASGTTP---QKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASV 1277
Query: 216 KKHRSES-ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA---PKSRRAHRSTSADSASS 271
K +E E +++K T +S RK + ++++ PA P+S++ + + + +
Sbjct: 1278 VKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEA 1337
Query: 272 SDTSRSRSRSAAAKTHTTALAG----RSPSPASGRRGEGDAPFSE----PGTTSTQRPSS 323
S + S ++ K +G + + G +G D P E GT S+
Sbjct: 1338 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSN 1397
Query: 324 PETATKQPSSPYEDKDKDKKE------KSATRPSPSPER 356
P++ ++ S KDK+KKE K++T+ S SP +
Sbjct: 1398 PKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1436
Score = 42.4 bits (98), Expect = 0.006
Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 7/144 (4%)
Query: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV-DGSSFDPQRRAREAKQPAPE 166
K + G +PA KK ++L A G S + +S + +A+ K
Sbjct: 1308 KRKLSGDQPAARTPRS------KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV 1361
Query: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
K S ++ ++ +K G + ++E+KKS K+KK + + E KK
Sbjct: 1362 KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1421
Query: 227 RKHRSPTPKSKRKSKDKKRKRSRS 250
+ ++ T S+ S+ KK+K+ ++
Sbjct: 1422 KAKKASTKDSESPSQKKKKKKKKT 1445
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 124 bits (310), Expect = 2e-27
Identities = 343/1517 (22%), Positives = 538/1517 (35%), Gaps = 242/1517 (15%)
Query: 1289 SQASLEAVEVPSMASSWGGP------HFSPEHKELSNSPLRENSFG----SPLEFRNSGP 1338
+ AS+E +P ++ G + SP + + SP R S G S GP
Sbjct: 179 TSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGP 238
Query: 1339 LGT------EMNTGFSSEVKEDLNGP-----FLNQLETDPSLDMKEQST--RSSGHSSSE 1385
T G S E + P L+ T PS E +T S G++ +
Sbjct: 239 THTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTT 298
Query: 1386 LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRT----PSRRSRS 1441
PD +G+ S+PV + T S + S +S +G P T PS + S
Sbjct: 299 RLPDNTTTSGLLE---ASTPVHSS---TGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTS 352
Query: 1442 GSSPGLRDG--SGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSP---EPKALPQTPRPR 1496
+ G + + HS S+P + + G SE +S+P P A TP P
Sbjct: 353 PAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE-ESTPVHSSPVATATTPPPA 411
Query: 1497 S--------------RSPSSPEL------------NNKCLTPQRERSGSESSVDQKTVAR 1530
RSP S + + + T + ++SS T A
Sbjct: 412 RSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAAL 471
Query: 1531 TPLGQRSRSGSSQELDVKPSASPQERSE----SDSSPDSKAKTRTPLRQRSRSGSSPEV- 1585
S GS++ + S++ RSE S SSPD+ A T P +GS+P V
Sbjct: 472 AHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLP------AGSTPSVL 525
Query: 1586 ---DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSG--S 1640
+ S +S + + P KP + ++ + S P++P LP S S
Sbjct: 526 VGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSS---PRSPDTTHLPASMTSSGVS 582
Query: 1641 SSKGRGPSPEGSSSTESSPEHP--PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698
S GS+ T + P P S SSP P + +P +S PE T
Sbjct: 583 EESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYT 642
Query: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758
S S ET + P S + + P S +R + SP TT R
Sbjct: 643 T-------FHSRPGSTET-TLLPDNTTASGLLEASMPVHSS--TRSPHTTLSPAGSTT-R 691
Query: 1759 RGRSPS----PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRR 1814
+G S + P + + + + S SS T+ RS + V
Sbjct: 692 QGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEE-- 749
Query: 1815 RGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR 1874
+ YHS + Q S GR TS + S AP S P ++
Sbjct: 750 --STTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH 807
Query: 1875 RSRSRT-----PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPP 1929
S T P S RS S ++ S+ T +RS S + S T P
Sbjct: 808 SSPGSTATTHFPDSSTTSGRSEES-IASHSSQDATGTIVLPARSTNSVLL---GESTTSP 863
Query: 1930 VTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPV 1989
+ S TT + TP ++ R + + P RS + T S +
Sbjct: 864 I----SSGSMETTALPGSTTTPGLSERSTTFHSSP----RSPATTLSPASTTSSGVSEES 915
Query: 1990 TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR------ 2043
T SR ++ T + T ++R + S + P + T LLP +
Sbjct: 916 TTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG-----STDTTLLPASTTTXLVGEP 970
Query: 2044 SRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT-PPATRNHSG- 2101
+ SP+ S T TA + T + +S + SS RS T PA+ SG
Sbjct: 971 TTSPI-----SSGSTETTALPGSTTTAG---LSEKSTTFYSSPRSPDTTLSPASTTSSGV 1022
Query: 2102 ---SRTPPVALNSSRMSCF----SRPSMSPTPLDRCRSPGMLEPLGSSR-TPMSVLQQAG 2153
S T S+ + F + P +S SPG + S R T S L
Sbjct: 1023 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPES 1082
Query: 2154 GSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQ--- 2210
+ GPG + T +P+N S + A T + T P ++S AG R +
Sbjct: 1083 TTFHSGPGST----ETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTT 1138
Query: 2211 ----------VPAP-------VPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTA 2253
+PAP V L + +++ + +AS+ + T +
Sbjct: 1139 FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSP 1198
Query: 2254 VNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTG 2313
V A + +PA + L TA S + P + + + + ++ + T
Sbjct: 1199 VAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI 1258
Query: 2314 SGTPPTAA----------NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAP 2363
S P T + + P S T P S+ G RS +TA + + L
Sbjct: 1259 SSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSG-RSEESTASHSSPDTNGITPLPA 1317
Query: 2364 ASLTSARMAPALSG-ANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSE 2422
TS R+A + + + S L++ G ++ + + SR+P S + MTS
Sbjct: 1318 HFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSS 1377
Query: 2423 R-APSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA 2481
+ P+S QA S P S S S +S + P + +LS G++
Sbjct: 1378 SISGEPTSLYSQAESTHTTA----FPASTTTSGLSQESTTF--HSKPGSTETTLSPGSI- 1430
Query: 2482 TTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541
TT+S A + PHS G SAL+ + PA S S++
Sbjct: 1431 TTSSFAQEFT---------TPHSQPG-----------SALSTVSPASTTVPGLSEESTTF 1470
Query: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSS-LPVQPEVALKRVPSP------------------ 2582
SS S+ +++ S S + S S+ S+ P P +P+
Sbjct: 1471 YSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSD 1530
Query: 2583 ----TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638
TP P + EPT S S + ++ +SSS+S + S++ +S S
Sbjct: 1531 ATGTTPLPARSTASDLVGEPTTFY----ISPSPTYTTLFPASSSTSGLTEESTTFHTSPS 1586
Query: 2639 SSSSSSSSSSPSPAKPG 2655
+S+ S+ S PG
Sbjct: 1587 FTSTIVSTESLETLAPG 1603
Score = 111 bits (277), Expect = 1e-23
Identities = 336/1460 (23%), Positives = 512/1460 (35%), Gaps = 235/1460 (16%)
Query: 1331 LEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDA 1390
+EF + G G GFS L P Q + + KE+ SS SEL+
Sbjct: 16 VEFASPGDDGDGRAEGFS------LGLPLSEQARAAGARE-KERQEVSSSPDVSELTATK 68
Query: 1391 VEKAGMS-SNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
E+ ++ S S S + + T ++SAS+P D + S G S
Sbjct: 69 HEETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPF----TTFSDYGVSVTFIT 124
Query: 1450 GS---------GTPSRHS----LSGSSPGMKDIPRTPSRGRSEC-----------DSSPE 1485
GS T S HS +S S PG PS + +S E
Sbjct: 125 GSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASME 184
Query: 1486 PKALPQTPRPRSRSP------SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRS 1539
ALP + S SSP ++ L+P R S S V +K+ SR
Sbjct: 185 TTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTS---SGVSEKSTT-----SHSRP 236
Query: 1540 GSSQELDVKPSAS-PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS 1598
G + + S + P ES +S T T L SP + S L P +
Sbjct: 237 GPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTL--------SPGTTTPSSLGPESTTF 288
Query: 1599 GSSPEVKDKPR------------AAPRAQSGSDSSPEPKAPAPRAL----PRRSRSGSSS 1642
SSP R A+ S + S +PA P +S SS
Sbjct: 289 HSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSS 348
Query: 1643 KGRGPSPEGSSST--------ESSPEHPP------KSRTARRGSRSSP---EPKTKSRTP 1685
K P+P G++S SSP P S T S+P P + TP
Sbjct: 349 KDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTP 408
Query: 1686 PRRRSSRS-----------SPELTRKARLSRRSRSASSSPE----------TRSRTPPR- 1723
P RS+ S SP T+ S ++ S E T+S TP
Sbjct: 409 PPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTT 468
Query: 1724 --------HRRSPSVSSPEPAEKS----RSSRRRRSASSPRTKTTS--RRGRSPS----- 1764
H S + + S RS + S SSP T+ G +PS
Sbjct: 469 AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGD 528
Query: 1765 --PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
P P + + T ++S + S+ R + + +T G S +
Sbjct: 529 STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSS--GVSEEST 586
Query: 1823 RSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPL 1882
S +R S+ T++ G + P S++ + S +SP P + S S T
Sbjct: 587 TSHSRPGSTHTTAFP--GSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTF 644
Query: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP---VSRRRSRSRTPPVTRRRSRSRT 1939
SR S T + + S SP +S S +R T S +
Sbjct: 645 HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSS 704
Query: 1940 PTTRRRSRSRTP----PVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSR 1995
TR + T P T + P T +RS TS + + +SP + +
Sbjct: 705 NDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMH 764
Query: 1996 SRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSR 2055
S T R T+ S S T I + + L+ S SP
Sbjct: 765 FPESDTTSGRGEESTT------SHSSTTHTISSAPSTTSALVEEPTSYHSSP------GS 812
Query: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
+ T + RS +I AS SS D + + PA +S V L S S
Sbjct: 813 TATTHFPDSSTTSGRSEESI----ASHSSQDATGTIVLPARSTNS------VLLGESTTS 862
Query: 2116 CFSRPSMSPTPLD-RCRSPGMLEPL----GSSRTPMSVLQQAGGSMMDGPGPRIPDHQRT 2170
S SM T L +PG+ E S R+P + L A + H R
Sbjct: 863 PISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRP 922
Query: 2171 SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLAS 2230
S T P S + GL+ + + PA+
Sbjct: 923 G-----------------STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTX 965
Query: 2231 RIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTP 2290
+ + + ++ S T A+P + A + + SP T ++P++ +
Sbjct: 966 LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 1025
Query: 2291 TAPAVNLAGA-RTPAALAALSLTGSGTPPTAANY-PSSSRTPQAPAS--ANLVGPRSAHA 2346
+ + + G+ T A + ++ G TA++ P S+ T +P S A+ +GP S
Sbjct: 1026 STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPEST-- 1083
Query: 2347 TAPVNIAGSRTAAALAPASLTSARMAPALSGANLT--SPRVPLSAYERVSGRTSPPLLDR 2404
+ T L P + T++ + A + + + SPR LS +G T+ +
Sbjct: 1084 --TFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSP----AGSTTR----Q 1133
Query: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIA 2464
S T S PS S+ T P+ +S + + S P S +P+ S
Sbjct: 1134 GESTTFQSWPS-SKDTMPAPPTTTSAFVELSTTSHGSP------SSIPTTHFSASSTTFG 1186
Query: 2465 QTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQ-PSALAA 2523
++ S S A ATT S A L V HS P ST P + A
Sbjct: 1187 RSEESTTVHS-SPVAPATTPSPARSTTSGL-VEESTAYHSS----PGSTQTMHFPESSTA 1240
Query: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSS------SSSSSSGSSSSDS--EGSSLPVQPEVA 2575
++E R+S SS++ + SS S++S+ S SS GS ++ E S+ + E +
Sbjct: 1241 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEES 1300
Query: 2576 LKRVPSP-----TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
SP TP P GR E T S ++ +S++++ S+ S+ S
Sbjct: 1301 TASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYS 1360
Query: 2631 SSSSSSSSSSSSSSSSSSPS 2650
SS S + S +S +SSS S
Sbjct: 1361 SSRSPDQTLSPASMTSSSIS 1380
Score = 110 bits (274), Expect = 2e-23
Identities = 353/1630 (21%), Positives = 571/1630 (35%), Gaps = 218/1630 (13%)
Query: 1024 SLVQSCPGSLSLCAGVKSSTPPGESY--FGVSSLQLKGQSQTSPDHRSDTSSPEVRQS-- 1079
S V + G + A SS+ P ++ +GVS + G + T S T+S +S
Sbjct: 88 STVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTV 147
Query: 1080 ---------------HSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
HS + + +TSP S ++ + + + + + F +S
Sbjct: 148 SHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSS 207
Query: 1125 PM-----------LKSGMSPEQSRFQSDSSSYPTV---DSNSLLGQSRLETAESKEKMAL 1170
P SG+S + + S T+ DS ++ G S+ TA ++
Sbjct: 208 PRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASH----SI 263
Query: 1171 PPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALP 1230
P D T SP + P PES+ S G + T+ LP
Sbjct: 264 PGSTDTTLSPG------TTTPSSLGPESTTF-----------HSSPGYTKTTR-----LP 301
Query: 1231 TSSQDEELMEV---VEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER-PAVSLTLDQ 1286
++ L+E V S LS SS E + F+S P ++ PA S T
Sbjct: 302 DNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSA 361
Query: 1287 SQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTG 1346
++ S SS HFS L +S SP+ + P +G
Sbjct: 362 FVKLSTT----YHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSG 417
Query: 1347 FSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPV 1406
E P Q P +S+ +SGHS + SS S ++
Sbjct: 418 HVEESTAYHRSPGSTQTMHFP------ESSTTSGHSEESATFHGSTTHTKSSTPSTTA-- 469
Query: 1407 LDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR----SGSSPGLRDGSGTPSRHSLSGS 1462
A+ T S + +D T S RS S SSP + P+ GS
Sbjct: 470 --ALAHTSYHSSLGSTETTHFRDS--STISGRSEESKASHSSPDAMATTVLPA-----GS 520
Query: 1463 SPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESS 1522
+P + TPS S S E ALP + S S + +P + + +S
Sbjct: 521 TPSVLVGDSTPSPISS---GSMETTALPGSTTKPGLSEKSTTFYSSPRSP--DTTHLPAS 575
Query: 1523 VDQKTVARTPLGQRSRSGSSQELDVKPSAS-PQERSESDSSPDSKAKTRTPLRQRSRSGS 1581
+ V+ SR GS+ S + P ES +S S T T L S + S
Sbjct: 576 MTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTAS 635
Query: 1582 S--PEVDSKSRLSPRRSRSGSSPE--VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS- 1636
S PE + SR GS+ + D A+ ++ ++P P S
Sbjct: 636 SLGPEYTTF------HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGST 689
Query: 1637 ---------RSGSSSKGRGPSP--------EGSSSTESSPEHPPKSRTARRGSRSS-PEP 1678
S SS P+P E S+++ SP P + + R + S E
Sbjct: 690 TRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEE 749
Query: 1679 KTKSRTPPRRRSSRSSPEL-TRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737
T + P + PE T R + S SS+ T S P + S EP
Sbjct: 750 STTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPS----TTSALVEEPTS 805
Query: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQST 1797
S + P + TTS R + S S ++ T T RS +S
Sbjct: 806 YHSSPGSTATTHFPDSSTTSGRSE---------ESIASHSSQDATGTIVLPARSTNSVLL 856
Query: 1798 SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857
S + GS + +P E S T R + T + S +
Sbjct: 857 GESTTSPISSGSMETTALPGS---TTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSE 913
Query: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR-SRSRAS 1916
+ SR ++ T + TP +SR + S +SP S + S T S
Sbjct: 914 ESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTS 973
Query: 1917 PVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP 1976
P+S + + P + + +T S R+P T + + + V+ + S + P
Sbjct: 974 PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 1033
Query: 1977 ITRRRSR---SRTSP-VTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS-- 2030
+ + S T P V++ + S +SP + + S S + S P + S
Sbjct: 1034 GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTT----ASSLGPESTTFHSGP 1089
Query: 2031 -RSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS----- 2084
+ T LLP + S A S ++ G T SP R ++
Sbjct: 1090 GSTETTLLPDNTTASGLLEA------STPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWP 1143
Query: 2085 SDRSRSATPP---------ATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGM 2135
S + PP +T +H + P S+ + F R S T +P
Sbjct: 1144 SSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPAT 1203
Query: 2136 LEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDH--QRTSVPENHAQSRIALALTAISLGTA 2193
+R+ S L + + PG H + ++ +SR + + T ++ +
Sbjct: 1204 TP--SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS- 1260
Query: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIP-- 2251
PPS ++A + S +P + + ++ + R ++A+ + + +P
Sbjct: 1261 --PPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAH 1318
Query: 2252 --TAVNLADSRT---PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAAL 2306
T+ +A+S T + LAS T SA + + +P L+ PA++
Sbjct: 1319 FTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLS----PASM 1374
Query: 2307 AALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASL 2366
+ S+ SG P + + S+ T PAS G S +T + GS T L+P S+
Sbjct: 1375 TSSSI--SGEPTSLYSQAESTHTTAFPASTTTSG-LSQESTTFHSKPGS-TETTLSPGSI 1430
Query: 2367 TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426
T++ A + T P SA VS ++ + P S ++ S
Sbjct: 1431 TTSSFAQEFT----TPHSQPGSALSTVSPAST-------------TVPGLSEESTTFYSS 1473
Query: 2427 PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486
P S A S S Q +P P + L A T + G +T S
Sbjct: 1474 PGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLT------TTDIGQESTAFHS 1527
Query: 2487 AGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSS 2546
+ D G +PA VGEP + P+ L PA S + S++ +S S
Sbjct: 1528 SSDATGTTPLPARSTASDLVGEPTTFYISPSPT-YTTLFPASSSTSGLTEESTTFHTSPS 1586
Query: 2547 SSSSSSSSSS 2556
+S+ S+ S
Sbjct: 1587 FTSTIVSTES 1596
Score = 107 bits (267), Expect = 2e-22
Identities = 282/1332 (21%), Positives = 443/1332 (33%), Gaps = 175/1332 (13%)
Query: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP-----LRQRSRSGSSPEVD 1586
PL +++R+ ++E +ER E SSPD T T + + SG S
Sbjct: 37 PLSEQARAAGARE---------KERQEVSSSPDVSELTATKHEETVINHSTFSGFSQITG 87
Query: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR- 1645
S S + + +S P S + L + SG S +
Sbjct: 88 STVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTV 147
Query: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
S G++ T P H S EPKT T ++ + P T A LS
Sbjct: 148 SHSGPGATGTTLFPSHSATSVFVG-------EPKTSPITSASMETT-ALPGSTTTAGLSE 199
Query: 1706 RSRSASSSPETRSRT-PPRHRRSPSVSSPEPAEKSR------------------SSRRRR 1746
+S + SSP + RT P S VS SR S
Sbjct: 200 KSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTA 259
Query: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ-RSR 1805
S S P + T+ + +P G + + S T+TTR D + +S S
Sbjct: 260 SHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSS 319
Query: 1806 SRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRS-RTSPAPWKRS 1864
+ S T S H P +S +S S T K S + +SP+ +
Sbjct: 320 TGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTT 379
Query: 1865 RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR 1924
AS T S TP+ S + + T P +R + + RS S +
Sbjct: 380 HFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPE 439
Query: 1925 SRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRS 1984
S T S + +T ++S TP T + T S ++ T R S
Sbjct: 440 SSTTSGHSEESATFHGSTTH-TKSSTPSTTAALAH------TSYHSSLGSTETTHFRDSS 492
Query: 1985 RTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS 2044
S + S +SP + TP I S T L
Sbjct: 493 TISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPG 552
Query: 2045 RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS---G 2101
S + S R+P T S+T +SG S + + S + P + + + G
Sbjct: 553 LSEKSTTFYSSPRSPDTTHLPASMT----------SSGVSEESTTSHSRPGSTHTTAFPG 602
Query: 2102 SRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPG 2161
S T P S S SP P D SPG T S L + PG
Sbjct: 603 STTMPGLSQESTAS-----HSSPGPTDTTLSPGS--------TTASSLGPEYTTFHSRPG 649
Query: 2162 PRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLR 2221
+ T +P+N S + A + T P ++S AG R + +
Sbjct: 650 ST----ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGEST------TFH 699
Query: 2222 TAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSA 2281
+ P++N P + +A S + P+++ + A + L T S
Sbjct: 700 SWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSI--PTTHISARSTTSGLVEESTTYHSSP 757
Query: 2282 VNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA----------NYPSSSRTPQ 2331
+ P + + G + + ++ + T S P T + + P S+ T
Sbjct: 758 GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH 817
Query: 2332 APASANLVGPR--------SAHATAPVNIAGSRTAAALAPASLTS--------------A 2369
P S+ G S AT + + T + L S TS +
Sbjct: 818 FPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGS 877
Query: 2370 RMAPALSGANLT---SPRVPLSAYERVSGRTSPPLLDRARSRTPPSA------------P 2414
P LS + T SPR P + S +S + S + P + P
Sbjct: 878 TTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP 937
Query: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS 2474
SR ++ SP S S +P + S+ S ++ L TT S+
Sbjct: 938 GLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEK 997
Query: 2475 LSSG-----------AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST---GAQQPSA 2520
++ + A+TTSS S PG H+ P ST G Q S
Sbjct: 998 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAF--PGSTTMPGVSQEST 1055
Query: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS--------GSSSSDSEGSSLPVQ- 2571
+ P + S S+++SS S++ S S +++S +S PV
Sbjct: 1056 ASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 1115
Query: 2572 ----PEVALKRVPSPTPAPKEAVREGRP--------PEPTPAKRKRRSSSSSSSSSSSSS 2619
P L S T + + P P T + S++S S SS +
Sbjct: 1116 STGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPT 1175
Query: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPR 2679
+ S+SS++ S S++ SS + +++PSPA+ L + ++ PG +++
Sbjct: 1176 THFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGS--TQTMH 1233
Query: 2680 KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETP 2739
P S RS SP S+ E + S + +H T
Sbjct: 1234 FPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTT 1293
Query: 2740 SPRPMRHRSSRS 2751
S R +S S
Sbjct: 1294 SGRSEESTASHS 1305
Score = 102 bits (255), Expect = 4e-21
Identities = 262/1159 (22%), Positives = 399/1159 (34%), Gaps = 181/1159 (15%)
Query: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807
E K S I+S + + P S + LS + + SSP ++ +P R + SG S+
Sbjct: 172 EPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTT 231
Query: 808 SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTP 867
S + P + + + P S T S S++ H P + SP S
Sbjct: 232 SHSRPGPTHTIAFP----DSTTMPGVSQESTASH-----SIPGSTDTTLSPGTTTPSSLG 282
Query: 868 QRRSCFESSPDPELKSRTPSRHSCSG---SSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS 924
+ F SSP +R P + SG +S P S+ P + S +SS + +
Sbjct: 283 PESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTF 342
Query: 925 PRQRSHSGSSSPSPSRVTS-----RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSP---D 976
S S +SP+PS TS TT S S +P ++ S HS S+P
Sbjct: 343 QSWPS-SKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHF-SASSTTLGHSEESTPVHSS 400
Query: 977 TKVKPETPP--RQSHSGSI--------SPYPKVKAQTPPGPSLSG-SKSPCPQEKSKDSL 1025
TPP R + SG + SP P + SG S+ S
Sbjct: 401 PVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT 460
Query: 1026 VQSCPGSLSLCA--GVKSSTPPGESYFGVSSLQLKGQSQTSPDHRS--DTSSPEVRQSHS 1081
S P + + A SS E+ S + G+S+ S S D + V + S
Sbjct: 461 KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGS 520
Query: 1082 ESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASP-----------MLKSG 1130
L S SP S ++ + ++ + + F +SP M SG
Sbjct: 521 TPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSG 580
Query: 1131 MSPEQSRFQSDSSSYPTV---DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK--- 1184
+S E + S S T S ++ G S+ TA P D T SP
Sbjct: 581 VSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS----PGPTDTTLSPGSTTASS 636
Query: 1185 --DKFSPFPVQDRP------------------ESSLVFKDTLRTPPRERSGAGSS----- 1219
+++ F RP E+S+ + R+P S AGS+
Sbjct: 637 LGPEYTTF--HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGE 694
Query: 1220 -------PETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSN--FES 1270
P + + A PT++ VE S G S ++ + ST++ E
Sbjct: 695 STTFHSWPSSNDTRPAPPTTTS-----AFVEPSTTSHGSPSSIPTTHISARSTTSGLVEE 749
Query: 1271 SPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGS- 1329
S P + T+ +S + E + + S S S S+ S
Sbjct: 750 STTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS 809
Query: 1330 -----PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTR--SSGHS 1382
F +S +S +D G + + S+ + E +T SSG
Sbjct: 810 PGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSM 869
Query: 1383 SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSG 1442
+ P + G+S S + PR+P+ S ++++ T R S
Sbjct: 870 ETTALPGSTTTPGLSER----STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGST 925
Query: 1443 SSPGLRDGSGTP--SRHS-LSGSSPGMKDIPRTPSRGRSECDSSP----------EPKAL 1489
+ D + TP SRHS S SSPG D P+ + P E AL
Sbjct: 926 HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTAL 985
Query: 1490 PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKP 1549
P + S S + +P + + S +S V+ SR GS+
Sbjct: 986 PGSTTTAGLSEKSTTFYSSPRSP--DTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 1043
Query: 1550 SAS-PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS--------------------- 1587
S + P ES +S S T T L RS + SS +S
Sbjct: 1044 STTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTA 1103
Query: 1588 -----------------KSRLSPRRS--RSGSS------PEVKDKPRAAPRAQSGSDSSP 1622
++ LSP S R G S P KD A P S
Sbjct: 1104 SGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS 1163
Query: 1623 EPKAPAPRALPRRSRSGSSSK-GRGPSPEGSSSTESSPEHPPKSRTARRGSRSS-PEPKT 1680
+P ++P S SS+ GR E S++ SSP P + + R + S E T
Sbjct: 1164 TTSHGSPSSIPTTHFSASSTTFGRS---EESTTVHSSPVAPATTPSPARSTTSGLVEEST 1220
Query: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
+ P + PE + + S SR++ SS +PP + S EP
Sbjct: 1221 AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP---STTSALVEEPTSYHS 1277
Query: 1741 SSRRRRSASSPRTKTTSRR 1759
S + P + TTS R
Sbjct: 1278 SPGSIATTHFPESSTTSGR 1296
Score = 94.7 bits (234), Expect = 1e-18
Identities = 294/1413 (20%), Positives = 472/1413 (33%), Gaps = 162/1413 (11%)
Query: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP-- 321
TSA +++ + + + K+ T + RSP + SE TTS RP
Sbjct: 179 TSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGP 238
Query: 322 ----SSPETATKQPSSPYEDKDKDKKEKSATRPSP-SPERSSTGPEPP--------APTP 368
+ P++ T S + T SP + SS GPE T
Sbjct: 239 THTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTT 298
Query: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPT 428
L + S A+TP+ +P + SP + P SS+ + P+P T
Sbjct: 299 RLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGT 358
Query: 429 KVSRHASSSPESPKPAPAPGSHREISSS----------------------PTSKNRSHGR 466
+ S+ P+ P +H SS+ P +++ + G
Sbjct: 359 TSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGH 418
Query: 467 AKRDKSHSHTP--SRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524
+ ++ +P ++ M S T+ + H++S +P + + +
Sbjct: 419 VEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHS 478
Query: 525 SRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT----RGRSRS----- 575
S R ++ GRS ++ S + AT G + S
Sbjct: 479 SLGSTETTHFRD----------SSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGD 528
Query: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635
TP+ T A S ++ +S + + R + PA S S S
Sbjct: 529 STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTS 588
Query: 636 RSRSPARRSGRSRSRTPARRGRSRSRT-------PARRGRSRSRTPARRSGRSRSRTPAR 688
SR P + + G S+ T P S T A G + +R
Sbjct: 589 HSR-PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSR 647
Query: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHS--RTPQRRGRSGSSSERKNKSRTSQRRSRSNS- 745
G + + + S L HS R+P S+ R+ +S T SN
Sbjct: 648 PGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDT 707
Query: 746 --SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG---------SSPCPKQKSQTPP 794
+P S + S SP S + +S R + SG SSP Q P
Sbjct: 708 RPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPE 767
Query: 795 RRSRSG----------------SSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSS 838
+ SG SS P S + SSP + P + S
Sbjct: 768 SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 827
Query: 839 SPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898
S + G+I P + SV + S + P + G S
Sbjct: 828 SEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERS 887
Query: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVT----SRTTPRRSR--- 951
+ PR SP+ + SP + +S + S + S P + T S TTP SR
Sbjct: 888 TTFHSSPR-SPATTLSPASTTSSGVS--EESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 944
Query: 952 -SVSPCSNVESRLLPRYSHSG-----SSSPDTKVKPETP--PRQSHSGSISPYPKVKAQT 1003
S S + ++ LLP + + ++SP + ET P + + +S +
Sbjct: 945 TSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 1004
Query: 1004 P--PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQS 1061
P P +LS + + + + S PGS A S+T PG S +S G +
Sbjct: 1005 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST 1064
Query: 1062 QTSPDHRSDTSS---PEVRQSHSESPSLQSK--SQTSPKGGRSRSSSPVTELASRSPIRQ 1116
T+ RS T+S PE HS S ++ + G +S+PV ++ SP
Sbjct: 1065 DTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPV-HSSTGSP--- 1120
Query: 1117 DRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176
+ SP + E + FQS SS T+ + + +E + + P
Sbjct: 1121 ---RTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHG---SPSSIP 1174
Query: 1177 TASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDE 1236
T F SS V T +P R + E+++A +S
Sbjct: 1175 TTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSG-----LVEESTAYHSSPGST 1229
Query: 1237 ELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAV 1296
+ M E S S S ST++ SSP V S S+
Sbjct: 1230 QTMHFPESSTASGRSEESRTS----HSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATT 1285
Query: 1297 EVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN 1356
P +++ G S E +SP P F SG + E T + S +
Sbjct: 1286 HFPESSTTSGR---SEESTASHSSPDTNGITPLPAHFTTSGRI-AESTTFYISPGSMETT 1341
Query: 1357 GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSR 1416
L T P L S +S+ SS SPD ++ SIS + S
Sbjct: 1342 ---LASTATTPGL-----SAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAEST 1393
Query: 1417 ERSSSASSPEMKDGLPRTPSRRSRSGSS-PGLRDGSGTPSR--------HSLSGSSPGMK 1467
++ +S + + S+ GS+ L GS T S HS GS+
Sbjct: 1394 HTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTV 1453
Query: 1468 DIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527
T G SE +S+ + T ++ ++++ TP + G +V T
Sbjct: 1454 SPASTTVPGLSE-ESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPAT 1512
Query: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESD 1560
+ T +GQ S + S + P + SD
Sbjct: 1513 LTTTDIGQESTAFHSSSDATGTTPLPARSTASD 1545
Score = 94.0 bits (232), Expect = 2e-18
Identities = 340/1579 (21%), Positives = 532/1579 (33%), Gaps = 215/1579 (13%)
Query: 240 SKDKKRKR-SRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP 298
+++K+R+ S S + + H T + ++ S S+ T T++ G + S
Sbjct: 47 AREKERQEVSSSPDVSELTATKHEETVINHSTFSGFSQ-----ITGSTVNTSIGGNTTSA 101
Query: 299 ASGRRGEGDAPFSEPGTTSTQRPSSPETATKQ------PSSPYEDKDKDKKEKSATRPSP 352
++ + FS+ G + T S TATK S E+ AT +
Sbjct: 102 STPSSSDPFTTFSDYGVSVTFITGS--TATKHFLDSSTNSGHSEESTVSHSGPGATGTTL 159
Query: 353 SPERSST----GPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN-PPSEASPTRDRSPPK 407
P S+T G +P + P T LS++ S SP R SP +
Sbjct: 160 FPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPAR 219
Query: 408 SPEK-LPQSSSSESSPPSPQPTKVSRHASSSP----ESPKPAPAPGSHREISSSPTSKNR 462
+ + + S++ S P P T +++ P ES PGS S T+
Sbjct: 220 TTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPS 279
Query: 463 SHGRAKRD--KSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQ 520
S G S +T + R+ + T G + TP HS + SP S ++
Sbjct: 280 SLGPESTTFHSSPGYTKTTRLPDN----TTTSGLLEASTPV---HSSTGSPHTTLSPAS- 331
Query: 521 RWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRS--RTP 578
S G + Q W S++T SPA G + + +
Sbjct: 332 ------STTHEGEPTTFQ--SWPSSKDT-----------------SPAPSGTTSAFVKLS 366
Query: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR-SRSRTPARRRSRTRSPVRRRS-- 635
S S TP S S T T S TP + + TP RS T V +
Sbjct: 367 TTYHSSPSSTPTTHFSASST-TLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAY 425
Query: 636 -RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRS 694
RS + S T + + ++S TP+ + + + + G + +
Sbjct: 426 HRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTET 485
Query: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754
R + S GRS + S SS + + + S + S I
Sbjct: 486 THFRDSSTIS------GRS-----EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPI 534
Query: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814
SS + + P S K LS + + SSP + P + SG S+ S + P
Sbjct: 535 SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGS 594
Query: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
+ +++ P + S SSP P + +P GS T+ + T F
Sbjct: 595 THTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP---GSTTASSLGPEYTT------FH 645
Query: 875 SSPDPELKSRTPSRHSCSG---SSPPRVKSSTPPRQ--SPSRSSSPQPKVKAIISPRQRS 929
S P + P + SG +S P S+ P SP+ S++ Q + S
Sbjct: 646 SRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHS---WP 702
Query: 930 HSGSSSPSPSRVTS-----RTTPRRSRSVSPCSNVESRL----LPRYSHSGSSSPDTKVK 980
S + P+P TS TT S S P +++ +R L S + SSP +
Sbjct: 703 SSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 762
Query: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVK 1040
P + SG + T ++S + S + + S PGS +
Sbjct: 763 MHFPESDTTSGRGEESTTSHSSTT--HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD 820
Query: 1041 SSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSR 1100
SST G S ++S + + T T+S + +S + S S T+ G +
Sbjct: 821 SSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTT 880
Query: 1101 SSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV---DSNSLLGQS 1157
S R S + SG+S E + S S T DS + G S
Sbjct: 881 PGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS 940
Query: 1158 RLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAG 1217
R T P D T P + + P +G
Sbjct: 941 RHSTTSHSS----PGSTDTTLLP------------------ASTTTXLVGEPTTSPISSG 978
Query: 1218 SSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER 1277
S+ + +ALP S+ L E + S S +S ++ SS EE
Sbjct: 979 ST-----ETTALPGSTTTAGL-------SEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1026
Query: 1278 PAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSP--LRENSFGSPLEFRN 1335
+ + A + +P ++ H SP + + SP +S G +
Sbjct: 1027 TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFH 1086
Query: 1336 SGPLGTEM-----NT------GFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS 1384
SGP TE NT S+ V P + E +T S SS
Sbjct: 1087 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSK 1146
Query: 1385 ELSPD---------AVEKAGMSSNQSISSPVLDAVPRTPSR-ERSSSASSPEMKDGLPRT 1434
+ P + S SI + A T R E S++ S + +
Sbjct: 1147 DTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPS 1206
Query: 1435 PSRRSRSG---------SSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSP- 1484
P+R + SG SSPG P + SG S + RT + SSP
Sbjct: 1207 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS----EESRTSHSSTTHTISSPP 1262
Query: 1485 -EPKALPQTPRPRSRSPSS------PELNNKCLTPQRERSGSESSVDQKTVARTP--LGQ 1535
AL + P SP S PE ++ E + S SS D + P
Sbjct: 1263 STTSALVEEPTSYHSSPGSIATTHFPE-SSTTSGRSEESTASHSSPDTNGITPLPAHFTT 1321
Query: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRR 1595
R S + P + + + ++P AK+ T L SRS LSP
Sbjct: 1322 SGRIAESTTFYISPGSMETTLASTATTPGLSAKS-TILYSSSRS-------PDQTLSP-- 1371
Query: 1596 SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSST 1655
S +S + +P + + ++ P + L + S + S GS+ T
Sbjct: 1372 -ASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSK-------PGSTET 1423
Query: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE 1715
SP S S + T + P S SP T LS S + SSP
Sbjct: 1424 TLSPGSITTS--------SFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPG 1475
Query: 1716 TRSRTPPRHRRSPSVSSPE 1734
+ T H + S+ S +
Sbjct: 1476 STETTAFSHSNTMSIHSQQ 1494
Score = 83.2 bits (204), Expect = 3e-15
Identities = 235/1096 (21%), Positives = 368/1096 (33%), Gaps = 133/1096 (12%)
Query: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEP 167
K TP A+ T + L + R + IS R+ E+K P
Sbjct: 461 KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG------------RSEESKASHSSP 508
Query: 168 PKPYSLVRESSSSRS-----PTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
+ V + S+ S TP + ++ P K ++ RS
Sbjct: 509 DAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPD 568
Query: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
+ + + S+ + R S TT P S T+ S T+ S S+
Sbjct: 569 TTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGS------TTMPGLSQESTA---SHSS 619
Query: 283 AAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQ------------RPSSP-ETATK 329
T TT G + + + G E S PG+T T S P ++T+
Sbjct: 620 PGPTDTTLSPGSTTASSLGP--EYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTR 677
Query: 330 QPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE---RHGGSPQPLATTPL 386
P + ++ +T P + T P PP T E GSP + TT +
Sbjct: 678 SPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHI 737
Query: 387 SQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPA 446
S T S P S + + S +S + T S S + + A
Sbjct: 738 SARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEEST-----TSHSSTTHTISSA 792
Query: 447 PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS 506
P + + PTS + S G + +H P RS + S+ T T +
Sbjct: 793 PSTTSALVEEPTSYHSSPG----STATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPA 848
Query: 507 RSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRS 566
RS + S + SP G + PG +T G S + S RS
Sbjct: 849 RS-------TNSVLLGESTTSPISSGSMETTALPG-----STTTPGLSERSTTFHSSPRS 896
Query: 567 PATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR 626
PAT S T + G S T + R S T + TP G SR T +
Sbjct: 897 PATTLSPASTTSS--GVSEESTTSHSRPGSTHTTAFPDSTTTP---GLSRHSTTSH---- 947
Query: 627 TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP 686
SP + + + T + + T A G S T A S +S +
Sbjct: 948 -SSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPG---STTTAGLSEKSTTFYS 1003
Query: 687 ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSS 746
+ R + +P S S SHSR + S SQ + S+SS
Sbjct: 1004 SPRSPDTTLSPASTTSSGVS-EESTTSHSRPGSTHTTAFPGS--TTMPGVSQESTASHSS 1060
Query: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG---SSQ 803
P + + SPRS S L + S P + + P + SG +S
Sbjct: 1061 PGSTDTTL---------SPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEAST 1111
Query: 804 PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHP----------KVKSGTPPRQG 853
P S PR + S + +Q T + SS P ++ + +
Sbjct: 1112 PVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS 1171
Query: 854 SITSPQANEQSVT---PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS 910
SI + + S T + + SSP + +P+R + SG V+ ST SP
Sbjct: 1172 SIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSG----LVEESTAYHSSPG 1227
Query: 911 RSSS---PQPKVKAIISPRQR-SHSGSS---SPSPSRVTSRTTPRRSRSVSPCSNVESRL 963
+ + P+ + S R SHS ++ S PS ++ S SP S +
Sbjct: 1228 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHF 1287
Query: 964 LPRYSHSG--------SSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSP 1015
+ SG SSPDT P + SG I+ + S +
Sbjct: 1288 PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTAT 1347
Query: 1016 CPQEKSKDSLVQS---CPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTS 1072
P +K +++ S P A + SS+ GE +SL + +S + + T+
Sbjct: 1348 TPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEP----TSLYSQAESTHTTAFPASTT 1403
Query: 1073 SPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELAS-RSPIRQDRGEFSASPMLKSGM 1131
+ + Q + S ++T+ G +SS E + S S + G+
Sbjct: 1404 TSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGL 1463
Query: 1132 SPEQSRFQSDSSSYPT 1147
S E + F S S T
Sbjct: 1464 SEESTTFYSSPGSTET 1479
Score = 42.0 bits (97), Expect = 0.008
Identities = 68/311 (21%), Positives = 106/311 (34%), Gaps = 32/311 (10%)
Query: 160 AKQPAPEPPKPYSLVRESSSSRSPT--------PKQKKKKKKKDRGRRSESSS------- 204
A P+P LV ES++ S P+ + + R S SS+
Sbjct: 1202 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 1261
Query: 205 PRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST 264
P + + S S H + + +S++ S T AH +T
Sbjct: 1262 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 1321
Query: 265 SADSASSSD---TSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321
S A S+ + S + A+ T L+ +S S R D S TS+
Sbjct: 1322 SGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSP-DQTLSPASMTSSSIS 1380
Query: 322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381
P + Q S + ++T S + S+T P T SP +
Sbjct: 1381 GEPTSLYSQAESTHTTAFP-----ASTTTSGLSQESTTFHSKPGSTETTL-----SPGSI 1430
Query: 382 ATTPLSQEPVNPPSEASPTRDRSPPKS---PEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
T+ +QE P S+ P S P +S++ SSP S + T S + S
Sbjct: 1431 TTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSI 1490
Query: 439 ESPKPAPAPGS 449
S + P P S
Sbjct: 1491 HSQQSTPFPDS 1501
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 123 bits (309), Expect = 2e-27
Identities = 232/1141 (20%), Positives = 419/1141 (36%), Gaps = 174/1141 (15%)
Query: 85 QQIQEKVATFRL-MLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERL-------- 135
+ IQE ++ L L + GG+ P+ E + E +N L
Sbjct: 329 KNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTEN 388
Query: 136 --RAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKK 193
R A + + G + + + A E P P + R ++ + +P+P + + +
Sbjct: 389 RERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHG-ERTANENTTPSPAEPTEHGE 447
Query: 194 KDRGRRSESS----SPRRERKKSSKKKKHRSESESKKRKHRSP------TPKSKRKSKDK 243
+ + S + ER + K S +ES + R+P TP ++++
Sbjct: 448 RTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENR 507
Query: 244 KRKRSRSTTPAPKSRRAHRSTSADSASS-SDTSRSRSRSAAAKTHTTALAGRSPSPASGR 302
+R + +TTP+P +R T+A+ ++ S + +R A TT PSPA
Sbjct: 508 ERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTT------PSPAEPT 561
Query: 303 RGEGDAPFSEPGTTST---------QRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS 353
PF+ TTS+ + P + E T P+ P E++++ EK T PSP+
Sbjct: 562 ENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEK--TTPSPA 619
Query: 354 PERSSTGPEPP----APTPLLAE-RHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408
E + G P TP LAE G P A +E + + P +
Sbjct: 620 -EPTENGDRTPLANEKTTPSLAEPTENGQRTPFA------------NEKTTSSSAEPTEH 666
Query: 409 PEKLPQSSSSESSPPSP-QPTKVSRHASSSPESPKPAPAPGSHREISSS------PTSKN 461
E+ P ++E++ PSP +PT+ ++ +P PA P +RE++++ P
Sbjct: 667 EERTP--LANENTTPSPAEPTENRERTANENTTPSPA-GPTENREMTANEKTTLFPAEPT 723
Query: 462 RSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR 521
+ R +K+ S R+P ++ S S PT+ G R+P + +
Sbjct: 724 ENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHG---ERTPLANENTTLSP 780
Query: 522 WGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARR 581
G + + +R ++ P + T+ R R+ + + + SPA + RTP
Sbjct: 781 AGPTENRERTANEKTTPFP----AEPTENRERTAN----ENTTPSPAQPTENGDRTPLAN 832
Query: 582 GRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPA 641
++ + RTP + + A RTP + T SP + +
Sbjct: 833 EKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPA---EPTENRE 889
Query: 642 RRSGRSRSRTPARRGRSRSRT--------PARRGRSRSRTPARRSGRSRSRTPARRGRSR 693
R + ++ PA +R T PA +R T + + + +PA
Sbjct: 890 RTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWT----ANENTTLSPAEPTEHE 945
Query: 694 SRTPRRGRSRSRSLVRRGRSHSRTPQ----RRGRSGSSSERKNKSRTSQRRSRSNSSPEM 749
TP ++ R+G R +GS S ++ TS S S ++
Sbjct: 946 EMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASST 1005
Query: 750 KKSRISSRRSRSLSSPRSK----------------AKSRLSLRRSLSGSSPCPKQKSQT- 792
S S S + P S S L+L +L+ ++ S T
Sbjct: 1006 ASSTASEITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTV 1065
Query: 793 ---PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP 849
P S SGS A T + ++ + T + + S PH K+ T
Sbjct: 1066 TSVPTTASTSGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTD 1125
Query: 850 PRQGSI--TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ 907
S+ T P+ N SV S+P S+ P S T
Sbjct: 1126 TTTASVSATVPKNNTLSV-------ITSTP----------------STAPNTASKTMTTA 1162
Query: 908 SPSRSSSPQPKV-KAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPR 966
S + ++S + + + + +GS P+ S S TT +++ + VES
Sbjct: 1163 SKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASG--TTVES----- 1215
Query: 967 YSHSGSSSPDTKVKPET---PPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKD 1023
+ S++P T + T P S +GS + + P + S+S E ++
Sbjct: 1216 ---APSTAPPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRA 1272
Query: 1024 S----------LVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSS 1073
S GS + K+ +S F +++ ++T+ S T+S
Sbjct: 1273 STSATEVTTAMTTAMTTGSETAVVSTKAPVTTTQSGFSTATVM---PAKTTTASVSTTAS 1329
Query: 1074 PEVRQSHSESPSLQSKSQTSPKGGRSRSSSPV----TELASRSPIRQDRGEFSASPMLKS 1129
+ Q+ +S + + S +S + S + T + ++P E + + ++ S
Sbjct: 1330 TTLYQNTIDSVAKSVPTMDSTIASKSTTLSKIVSVPTAVFIKAPETTTGSEITLASIITS 1389
Query: 1130 G 1130
G
Sbjct: 1390 G 1390
Score = 115 bits (288), Expect = 6e-25
Identities = 225/1126 (19%), Positives = 409/1126 (36%), Gaps = 154/1126 (13%)
Query: 162 QPAPEPPKPYSLVRESSSSRS----PTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK 217
+P +P + SS+ + PT ++ + KD R++ S + + K
Sbjct: 156 KPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHK--- 212
Query: 218 HRSESESKKRKHRSPTPKSK---RKSKDKK----RKRSRSTTPAPK--------SRRAHR 262
ES +KH +P PKSK RKS K RK ++ P K S +H+
Sbjct: 213 -----ESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHK 267
Query: 263 STSADSASSSDTSRSRSRS------AAAKT--HTTALAGRSPSPASGRRGEGDAPFSEPG 314
+T++ S + ++ +S S AA+KT TT S R
Sbjct: 268 TTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKT 327
Query: 315 TTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS-PSPERSSTGPEPPAPTPLLAER 373
T + Q S T+ + P E + E + P+ P+ R T E +P
Sbjct: 328 TKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSP----- 382
Query: 374 HGGSPQPLATTPLSQEPVNPPSEASPTRDRSP---------PKSPEKLPQSSSSESSPPS 424
+P + P A PT +R P P + + +++E++ PS
Sbjct: 383 ----AEPTENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPS 438
Query: 425 P-QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGR 483
P +PT+ ++ +P PA P H E + K S A+ + TP
Sbjct: 439 PAEPTEHGERTANENTTPSPA-EPTEHGERTPFANDKTTS-SSAESTEHGERTPLANENT 496
Query: 484 SRSPATAKRGRSR----SRTPTKRGHSRSR----------SPQWRRSRSAQRWGRSRSPQ 529
+ SPA R R + TP+ G + +R SP +P
Sbjct: 497 TPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPS 556
Query: 530 RRGRSRSPQRPGWSRSRNTQRRGR-----SRSARRGRSHSRSPATRGRSRSRT------- 577
+ + QR ++ + T R+ + + SPA +R RT
Sbjct: 557 PAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTP 616
Query: 578 -PARRGRSRSRTP-ARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635
PA + RTP A ++ + RTP ++ S + R+P+ +
Sbjct: 617 SPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANEN 676
Query: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
+ SPA + +R RT + + TP+ G + +R + + PA +R R
Sbjct: 677 TTPSPAEPT-ENRERT-----ANENTTPSPAGPTENR--EMTANEKTTLFPAEPTENRER 728
Query: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT---SQRRSRSNSSPEMKKS 752
T + S + + + S S+ ++ RT ++ + S + P +
Sbjct: 729 TANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRE 788
Query: 753 RISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS--QPKAKSRT 810
R ++ ++ + ++ + R + + + + +TP ++ S +P +
Sbjct: 789 RTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKR 848
Query: 811 PP---RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT----SPQANEQ 863
P ++ SSS+ P + +TP +++SSP ++ T P N +
Sbjct: 849 TPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRE 908
Query: 864 SVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP-----PRQSPSRSSSPQPK 918
S ++ + F + P + + S + P + TP Q+P R S +
Sbjct: 909 STANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAER 968
Query: 919 VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRL-LPRYSHSGSSSPDT 977
K I + + SS + +TS T + + S S+ S + + + SS+
Sbjct: 969 PKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYE 1028
Query: 978 KVKPETPPRQSHSGSISPYPKVKAQT--------------PPGPSLSGSKSPCPQEKS-K 1022
++ T + + SI A T P S SGSK+ E +
Sbjct: 1029 TIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMS 1088
Query: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDT-----SSPEVR 1077
++ + + S ++S ES V K + T+ S T + +
Sbjct: 1089 ETTIAAITASEDTTVSTQTSVIAAES---VPHTATKTPTDTTTASVSATVPKNNTLSVIT 1145
Query: 1078 QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMS-PEQS 1136
+ S +P+ SK+ T+ ++ ++S +T L + F+ + + +G P S
Sbjct: 1146 STPSTAPNTASKTMTT--ASKTTTTSTITSLPTT--------VFTTTSKITAGSEIPTAS 1195
Query: 1137 RFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALP-PQEDATASPP 1181
S +++ T S + T ES A P P E TAS P
Sbjct: 1196 TTDSATTAISTKASGT--------TVESAPSTAPPTPAETTTASVP 1233
Score = 105 bits (261), Expect = 8e-22
Identities = 231/1215 (19%), Positives = 439/1215 (36%), Gaps = 122/1215 (10%)
Query: 1491 QTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVA-RTPLGQRSRSGSSQELDVKP 1549
Q P +S E C T + + + + + KT+ ++ +S+E
Sbjct: 131 QRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQ 190
Query: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609
P R++ P T + +P KS+++ R+S +G S +
Sbjct: 191 GKDPMIRNQRSVDPADSTTTHKESAGKKHITPAP----KSKINCRKSTTGKSTVTRK--- 243
Query: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTAR 1669
SD + P + L + S S + + S + + S P K A
Sbjct: 244 --------SDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAAS 295
Query: 1670 RGS-RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH--RR 1726
+ + +++ P+ +T R + S LT+ + + + SA+ ++ + P H R
Sbjct: 296 KTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAE-PTEHGGRT 354
Query: 1727 SPSVSSPEPAEKSRSSRRRRSAS---SPRTKTTSRR---GRSPSPKPRGLQRSRSRSRRE 1780
+ ++P PAE + + R + + SP T +R + +P P G +R + E
Sbjct: 355 ANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANE 414
Query: 1781 KT-----RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG-----YHSRSPARQES 1830
T T +R+ + +T + + R S + R+P +
Sbjct: 415 NTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDK 474
Query: 1831 SRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS-- 1888
+ +SS P + + T+P+P + + +R A + S R +
Sbjct: 475 TTSSSAESTEHGERTPLANEN----TTPSPAEPTENRERTANENTTPSPAGPTENRETTA 530
Query: 1889 --RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946
++ SPV +R T+ ++ SP + RTP + + S T
Sbjct: 531 NEKTTLSPVEPTENRETTA----NEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGE 586
Query: 1947 RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2006
R TP + S P +R RT+ ++ SP + RT + +
Sbjct: 587 R--TPLANENTTPSPAEPT---ENRERTA-----NEKTTPSPAEPTENGDRTPLANEKTT 636
Query: 2007 RSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKR 2066
S P + RTP A + + S + R+PLA + + TP A
Sbjct: 637 PSLAEPT---ENGQRTPFANEKTTSSSAEPTEHEE---RTPLA----NENTTPSPAEPTE 686
Query: 2067 SLTRSPPAIRRRSASGSSSDRSRSATP-----PATRNHSGSRTPPVALNSSRMSCFSRPS 2121
+ R+ S +G + +R +A PA + RT SS
Sbjct: 687 NRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQ 746
Query: 2122 MSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGP-----RIPDHQRTSVPENH 2176
+P ++ S RTP++ + + GP R + + T P
Sbjct: 747 RTPFANEKTTSSSAEPTEHGERTPLA----NENTTLSPAGPTENRERTANEKTTPFPAEP 802
Query: 2177 AQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAAN----LASRI 2232
++R A + A+P + LA + P + + P AN +S
Sbjct: 803 TENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAE 862
Query: 2233 PAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTA 2292
P A LA+ T + P RT A P T S N P
Sbjct: 863 PTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEP-TENRESTANEKTTPFPAE 921
Query: 2293 PAVN---LAGARTPAALAALSLTGSGTP-------PTAANYPSSSRTPQAPASANLVGPR 2342
P N A T + A + TP S + P+ A +
Sbjct: 922 PTENREWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPK-DICATVASTT 980
Query: 2343 SAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYE--RVSGRTSPP 2400
+ ++ I S T + A AS T++ A ++ ++ P V +AYE R S S P
Sbjct: 981 GSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIP-VSSTAYETIRFSTAVSEP 1039
Query: 2401 LLDR--ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQ 2458
+ A T + TS S + + S++ + + + + +
Sbjct: 1040 VTASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITASE 1099
Query: 2459 SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQP 2518
+ QT+ +A ++S+ A T T + SV A VP ++ ST + P
Sbjct: 1100 DTTVSTQTSVIA-AESVPHTATKTPTDTT-----TASVSAT-VPKNNTLSVITSTPSTAP 1152
Query: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
+ + + +++S+ +S ++ +++S ++ S ++S ++ ++ + + +
Sbjct: 1153 NTASKTMTTASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTT 1212
Query: 2579 VPS-PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637
V S P+ AP PTPA+ S +++S++ S ++ + SS ++ +++S
Sbjct: 1213 VESAPSTAP-----------PTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATAS 1261
Query: 2638 SSSSSSSSSSSPSPA 2652
SS+ S ++ + + A
Sbjct: 1262 ESSTGSETTRASTSA 1276
Score = 99.0 bits (245), Expect = 6e-20
Identities = 260/1332 (19%), Positives = 447/1332 (33%), Gaps = 172/1332 (12%)
Query: 1059 GQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDR 1118
G S+T DH+S T + E + E+ S Q K P RS P + ++
Sbjct: 163 GNSKTI-DHKSSTDNHEAPPTSEENSSNQGKD---PMIRNQRSVDPADSTTTH---KESA 215
Query: 1119 GEFSASPMLKSGMSPEQSRF-------QSDSSSYPTVDSNSLLGQSRLETAESKEKMALP 1171
G+ +P KS ++ +S +SD + P S S L + T+ S K
Sbjct: 216 GKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDK----TSTSSHKTTTS 271
Query: 1172 PQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPT 1231
+ + K K + FP + S +K T TP S T
Sbjct: 272 FHNSGNS---QTKQKSTSFPEKITAASKTTYKTT-GTPEESEKTEDSRTTVASDKLLTKT 327
Query: 1232 SSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPA-VSLTLDQSQSQ 1290
+ +E + E ++ A + H E +T + E ER A + TL ++
Sbjct: 328 TKNIQETISANELTQSLA-EPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPT 386
Query: 1291 ASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSE 1350
+ E + A GP E++E++ + EN+ P E G NT S
Sbjct: 387 ENRERTANENTAPFPAGP---TENREMTAN---ENTTLFPAEPTEHGERTANENTTPSPA 440
Query: 1351 VKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAV 1410
+ N+ T + E R+ P A +K SS +S
Sbjct: 441 EPTEHGERTANENTTPSPAEPTEHGERT---------PFANDKTTSSSAESTEHG----- 486
Query: 1411 PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIP 1470
RTP +++ S E + RT + + + T +R + + + +
Sbjct: 487 ERTPLANENTTPSPAEPTENRERTANENTTPSPA------GPTENRETTANEKTTLSPVE 540
Query: 1471 RTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR 1530
T +R +++ K P P +P N E++ S S+ + R
Sbjct: 541 PTENR-----ETTANEKTTPSPAEPTENGQRTPFAN--------EKTTSSSAEPTEHGER 587
Query: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
TPL + + S E + E++ + ++ RTPL + S E +
Sbjct: 588 TPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQ 647
Query: 1591 LSP--RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
+P + SS E + P A +++P P A P +R ++++ PS
Sbjct: 648 RTPFANEKTTSSSAEPTEHEERTPLANE--NTTPSP------AEPTENRERTANENTTPS 699
Query: 1649 PEG---------SSSTESSPEHPP--KSRTARRGSRSSPEPKTKS--RTP-PRRRSSRSS 1694
P G + T P P + RTA + SSP T++ RTP +++ SS
Sbjct: 700 PAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSS 759
Query: 1695 PELTRKA-RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753
E T R + + + SP T R R + ++P PAE + + R
Sbjct: 760 AEPTEHGERTPLANENTTLSP--AGPTENRERTANEKTTPFPAEPTENRER--------- 808
Query: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813
T+ +PSP R+ EKT T + + + + T +++ S S
Sbjct: 809 --TANENTTPSPAQPTENGDRTPLANEKT-TPSLAEPTENGKRTPFANEKTTSSSAEPTE 865
Query: 1814 RRGGSGYHSRSPARQESSRTSSRRRRGRSRT-----PPTSRKRS--RSRTSPAPWKRSRS 1866
+ + + + T +R R +T PT + S +T+P P + + +
Sbjct: 866 HAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTEN 925
Query: 1867 R---------ASPATHRRSRSRTPLISRRR------------------------SRSRTS 1893
R SPA TPL+ + S +S
Sbjct: 926 REWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGSESS 985
Query: 1894 PVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPV 1953
S + S SV+ S + +S S S PV+ S T R S + + PV
Sbjct: 986 TASEIITSSTMSVSATASSTASSTASEITMSSAAIPVS-----STAYETIRFSTAVSEPV 1040
Query: 1954 TRRRSRSRTPPVTRRRSRSRTS------PITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2007
T + S + TS P T S S+ + T
Sbjct: 1041 TASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITASED 1100
Query: 2008 SRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRS 2067
+ S T + P + T + L++ + S P TA
Sbjct: 1101 TTVSTQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTA----- 1155
Query: 2068 LTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPL 2127
+++ + + + + + + ++ +GS P + S + S + T
Sbjct: 1156 -SKTMTTASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVE 1214
Query: 2128 DRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTA 2187
+P P + T SV + + G T+V ++S T
Sbjct: 1215 S---APSTAPPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTR 1271
Query: 2188 ISLGTARPPPSMSAA---GLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLAS 2244
S +M+ A G + APV T + A+ +PA + A +
Sbjct: 1272 ASTSATEVTTAMTTAMTTGSETAVVSTKAPV----TTTQSGFSTATVMPAKTTTASVSTT 1327
Query: 2245 ARTPAIPTAVNLADSRTP---AAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGAR 2301
A T ++ P + A+ + + P+AV + P T T + LA
Sbjct: 1328 ASTTLYQNTIDSVAKSVPTMDSTIASKSTTLSKIVSVPTAVFIKAPETTTGSEITLASII 1387
Query: 2302 TPAALAALSLTG 2313
T A G
Sbjct: 1388 TSGTTAVCDYIG 1399
Score = 98.2 bits (243), Expect = 1e-19
Identities = 215/1116 (19%), Positives = 404/1116 (36%), Gaps = 168/1116 (15%)
Query: 1685 PPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS-- 1742
PP S E R +R S+ + P S+T + + +P +E++ S+
Sbjct: 133 PPELPKSTEIHEQKRHCNTTRHSKP-TDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQG 191
Query: 1743 -----RRRRSASSPRTKTTSRRGRSP---SPKPRGLQRSRSRSRREKTRTTRRRDRSG-- 1792
R +RS + TT + +P P+ R +S K+ TR+ D++G
Sbjct: 192 KDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCR-KSTTGKSTVTRKSDKTGRP 250
Query: 1793 --SSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRK 1850
S ST + S ++ + G S +S + E +S+ + TP S K
Sbjct: 251 LEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEK 310
Query: 1851 RSRSRTSPAPWKR-----------------SRSRASPATH---RRSRSRTPLISR-RRSR 1889
SRT+ A K ++S A P H + + TP + +R
Sbjct: 311 TEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENR 370
Query: 1890 SRTSPVSRRRSRSRTSVTRRRSRSR------ASPVSRRRSRSRTPPV------TRRRSRS 1937
RT+ + S + + R R+ + A P R + T R+
Sbjct: 371 ERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERT 430
Query: 1938 RTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRS- 1996
T T R + + TP +P ++ S ++ T R+
Sbjct: 431 ANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTP 490
Query: 1997 ----RTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRS--RTPLLPRKRSRSRSPLAI 2050
T+P + +R + S P R + + +T L P + + +R A
Sbjct: 491 LANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTAN 550
Query: 2051 RRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALN 2110
+ + S T G+R+ P A + ++S + TP A N + S P N
Sbjct: 551 EKTTPSPAEPTENGQRT----PFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTE-N 605
Query: 2111 SSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRT 2170
R + +P+P + + G PL + +T S+ + P +
Sbjct: 606 RERTA---NEKTTPSPAEPTEN-GDRTPLANEKTTPSLAEPTENGQRT-PFANEKTTSSS 660
Query: 2171 SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLAS 2230
+ P H + R LA + A P + A + P+P R A +
Sbjct: 661 AEPTEH-EERTPLANENTTPSPAEPTENRERT---ANENTTPSPAGPTENREMTANEKTT 716
Query: 2231 RIPAASAA----AMNLASARTPAIPTA----VNLADSRTPAAAAAMNLASPRTAVAPSAV 2282
PA N + +PA PT A+ +T +++A RT +A
Sbjct: 717 LFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENT 776
Query: 2283 NLADPRTPTAPAVNLAGART------PAALAALSLTGSGTPPTAANYPSSSRTPQA--PA 2334
L+ P PT A +T P + + TP A + RTP A
Sbjct: 777 TLS-PAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKT 835
Query: 2335 SANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVS 2394
+ +L P P A +T ++ A + A P + +SP P ER +
Sbjct: 836 TPSLAEPTENGKRTP--FANEKTTSSSAEPT-EHAERTPLANENTTSSPAEPTENRERTA 892
Query: 2395 GRTSP-----PLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRS 2449
+ P +R + + P + T R + + +P++ P + + +
Sbjct: 893 NEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAE----PTEHEEMT 948
Query: 2450 PV-----------PSAFSDQSRCLIAQTTPVAGSQSLSSGAV---------ATTTSSAGD 2489
P+ + +++ + + A GS+S ++ + AT +S+A
Sbjct: 949 PLMVDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASS 1008
Query: 2490 HNGMLSVPAPGVPHSD-----------VGEPPASTGAQQPSALAALQPAKERRSSSSSSS 2538
+++ + +P S V EP ++ S LA + SS+ +S
Sbjct: 1009 TASEITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSV 1068
Query: 2539 SSSSSSSSSSSSSSSSSSGSSSS-----DSEGSSLPVQPEV-ALKRVP-----SPTPAPK 2587
+++S+S S ++++ ++ S ++ SE +++ Q V A + VP +PT
Sbjct: 1069 PTTASTSGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTT 1128
Query: 2588 EAVREGRPPE-------PTPAKRKRRSSSSSSSSSSSSSSSSSSS--------------- 2625
+V P TP+ +S + +++S ++++S+ +S
Sbjct: 1129 ASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTTSKITAG 1188
Query: 2626 -----SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
+S++ S++++ S+ +S ++ S+PS A P P
Sbjct: 1189 SEIPTASTTDSATTAISTKASGTTVESAPSTAPPTP 1224
Score = 87.4 bits (215), Expect = 2e-16
Identities = 242/1258 (19%), Positives = 440/1258 (34%), Gaps = 146/1258 (11%)
Query: 724 SGSSSERKNKSRTSQRR----SRSNSSPEMKKSRISSRRS----RSLSSPRSKA------ 769
+G+S +KS T S NSS + K I ++RS S ++ + A
Sbjct: 162 TGNSKTIDHKSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHIT 221
Query: 770 ---KSRLSLRRSLSGSSPCPKQKSQT--PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK 824
KS+++ R+S +G S ++ +T P +S S + S +S + K
Sbjct: 222 PAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTK 281
Query: 825 QKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQ---ANEQSVTPQRRSCFESSPDPEL 881
QKS T + +++S +GTP + A+++ +T ++ E+ EL
Sbjct: 282 QKS-TSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANEL 340
Query: 882 KS--RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS 939
P+ H ++ +++TP P+ + +SP + + + + + +
Sbjct: 341 TQSLAEPTEHGGRTAN----ENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANEN 396
Query: 940 RVTSRTTPRRSRSVSPCSNVESRLLP-RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPK 998
P +R ++ +N + L P + G + + P +P + G +
Sbjct: 397 TAPFPAGPTENREMT--ANENTTLFPAEPTEHGERTANENTTP-SPAEPTEHGERTANEN 453
Query: 999 VKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCP-GSLSLCAGVKSSTPPGESYFGVSSLQL 1057
+P P+ G ++P +K+ S +S G + A ++ P E + +
Sbjct: 454 T-TPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEP---TENRER 509
Query: 1058 KGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQD 1117
T+P T + E + K+ SP + E + SP
Sbjct: 510 TANENTTPSPAGPTENRET--------TANEKTTLSPVEPTENRETTANEKTTPSP---- 557
Query: 1118 RGEFSASPMLKSGMSPEQSRFQSDSSSYPTVD------SNSLLGQSRLETAESKEKMALP 1171
A P +P + + SS+ PT +N S E E++E+ A
Sbjct: 558 -----AEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANE 612
Query: 1172 PQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPT 1231
+ A P D+ + P + ++ RTP SS E E P
Sbjct: 613 KTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPL 672
Query: 1232 SSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQA 1291
++++ EP T N E + P+ + + + A
Sbjct: 673 ANEN-----TTPSPAEP----------------TENRERTANENTTPSPAGPTENREMTA 711
Query: 1292 SLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEV 1351
+ + P+ + E++E + + +S P E P E T S+E
Sbjct: 712 NEKTTLFPAEPT---------ENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEP 762
Query: 1352 KE-DLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSIS-SPV--L 1407
E P N+ T E R++ ++ + E ++N++ + SP
Sbjct: 763 TEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPT 822
Query: 1408 DAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMK 1467
+ RTP ++ S E + RTP ++ SS S P+ H+
Sbjct: 823 ENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSS------SAEPTEHA--------- 867
Query: 1468 DIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527
RTP + S E P R R+ + + + P ES+ ++KT
Sbjct: 868 --ERTPLANENTTSSPAE----PTENRERTANEKTTQF------PAEPTENRESTANEKT 915
Query: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
+R ++ E A P E E + + P RQ S P+
Sbjct: 916 TPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDE-NLQAPFRQGS-CAERPKDIC 973
Query: 1588 KSRLSPRRSRSGSSPEV--KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645
+ S S S ++ E+ + A S + S+ + A+P S + + +
Sbjct: 974 ATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYETIRFS 1033
Query: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
E +++ + E T + SS T + P +S S +A +S
Sbjct: 1034 TAVSEPVTASILALESTLAFTTVSNTTTSS----TVTSVPTTASTSGSKNTTACEATMSE 1089
Query: 1706 RSRSA-SSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPS 1764
+ +A ++S +T T + SV + ++ SA+ P+ T S +PS
Sbjct: 1090 TTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPS 1149
Query: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
P S++ + KT TT S TS + S++T + + S
Sbjct: 1150 TAPN--TASKTMTTASKTTTT--------STITSLPTTVFTTTSKITAGSEIPTASTTDS 1199
Query: 1825 PARQESSRTSSRR-RRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLI 1883
S++ S S PPT + + T+ P S + + H S +
Sbjct: 1200 ATTAISTKASGTTVESAPSTAPPTP---AETTTASVPTTTSTTGSENTGHHTVSSVPTTV 1256
Query: 1884 SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPT 1941
S S T + R S S T VT + + + S S PVT +S T T
Sbjct: 1257 FATASESSTGSETTRASTSATEVTTAMTTAMTTG-SETAVVSTKAPVTTTQSGFSTAT 1313
Score = 58.9 bits (141), Expect = 7e-08
Identities = 84/433 (19%), Positives = 164/433 (37%), Gaps = 77/433 (17%)
Query: 2354 GSRTAA---ALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP 2410
G RTA +PA T R A L SP P ER + + P
Sbjct: 351 GGRTANENNTPSPAEPTENRERTANENTTL-SPAEPTENRERTANENTAPF--------- 400
Query: 2411 PSAPSQSR-MTSERA----PSPSSRMGQAPSQSLLPPAQDQPR-----------SPVPSA 2454
P+ P+++R MT+ P+ + G+ + P+ +P +P P+
Sbjct: 401 PAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAE 460
Query: 2455 FSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP--------HSDV 2506
++ + TP A ++ SS A +T + P+P P + +
Sbjct: 461 PTEHG-----ERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENT 515
Query: 2507 GEPPAS------TGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS-----SSSSSS 2555
PA T A + + L+ ++P + R ++++ ++ S + + + ++ ++
Sbjct: 516 TPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTT 575
Query: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEP---------TP-AKRKR 2605
S S+ G P+ E PT + E P P TP A K
Sbjct: 576 SSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKT 635
Query: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP--------GPQ 2657
S + + + + ++ ++SSS+ + + ++ +++PSPA+P
Sbjct: 636 TPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN 695
Query: 2658 ALPKPASP---KKPPPGERRSRSPRKPIDSLR--DSRSLSYSPVERRRPSPQ-PSPRDQQ 2711
P PA P ++ E+ + P +P ++ + + SP E + P ++
Sbjct: 696 TTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKT 755
Query: 2712 SSSSERGSRRGQR 2724
+SSS + G+R
Sbjct: 756 TSSSAEPTEHGER 768
Score = 56.2 bits (134), Expect = 4e-07
Identities = 88/518 (16%), Positives = 177/518 (34%), Gaps = 34/518 (6%)
Query: 2247 TPAIPTA--VNLADSRTPAAAAAMNLASPRTA---VAPSAVNLADPRTPTAPAVNLAGAR 2301
+PA PT A+ T + A RTA AP + R TA
Sbjct: 362 SPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFPA 421
Query: 2302 TPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAAL 2361
P + + TP A RT + + P P A +T ++
Sbjct: 422 EPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTP--FANDKTTSSS 479
Query: 2362 APASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTS 2421
A ++ R P + SP P ER + + P P+ P+++R T+
Sbjct: 480 AESTEHGER-TPLANENTTPSPAEPTENRERTANENTTP---------SPAGPTENRETT 529
Query: 2422 ERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA 2481
+ S + P+++ A ++ +P P+ ++ Q TP A ++ SS A
Sbjct: 530 ANEKTTLSPV--EPTENRETTANEKT-TPSPAEPTENG-----QRTPFANEKTTSSSAEP 581
Query: 2482 TTTSSAGDHNGMLSVPAPGVPHSD---VGEPPASTGAQQPSALAALQPAKERRSSSSSSS 2538
T + P+P P + + +P+ P +++ S +
Sbjct: 582 TEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAE 641
Query: 2539 SSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEP 2598
+ + + ++ ++SS + ++ E + P+ E PT + E P P
Sbjct: 642 PTENGQRTPFANEKTTSSSAEPTEHEERT-PLANENTTPSPAEPTENRERTANENTTPSP 700
Query: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658
R +++ ++ + + + +++ ++SS + + + + + A
Sbjct: 701 AGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSA 760
Query: 2659 LPKPASPKKPPPGERRSRSPRKPIDSLRDSRS-----LSYSPVERRRPSPQPSPRDQQSS 2713
P + P E + SP P ++ + + P E R + + +
Sbjct: 761 EPTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQ 820
Query: 2714 SSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
+E G R + +PS E P + + S
Sbjct: 821 PTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTS 858
Score = 55.8 bits (133), Expect = 6e-07
Identities = 153/857 (17%), Positives = 287/857 (33%), Gaps = 151/857 (17%)
Query: 1935 SRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRS---RTSPVTR 1991
+R PT + S+T PP + S ++ R RS S T
Sbjct: 152 TRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTH 211
Query: 1992 RRSRSRT-------SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS 2044
+ S + S + R+S + S VTR+ ++ P +S + L S
Sbjct: 212 KESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRP-----LEKSMSTLDKTSTSSH 266
Query: 2045 RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRT 2104
++ + S+T K+ T P I + S + + TP + SRT
Sbjct: 267 KTTTSFHNSGNSQT------KQKSTSFPEKI----TAASKTTYKTTGTPEESEKTEDSRT 316
Query: 2105 PPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRI 2164
+ S ++ + ++ T + + EP G R
Sbjct: 317 ---TVASDKLLTKTTKNIQETISANELTQSLAEPTEH-------------------GGRT 354
Query: 2165 PDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAP 2224
+ T P ++R A +L A P + A + P P R
Sbjct: 355 ANENNTPSPAEPTENRERTANENTTLSPAEPTENRERT---ANENTAPFPAGPTENREMT 411
Query: 2225 AANLASRIPAASAA----AMNLASARTPAIPT--AVNLADSRTPAAAAAMNLASPRTAVA 2278
A + PA N + +PA PT A+ T + A RT A
Sbjct: 412 ANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFA 471
Query: 2279 PSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANL 2338
D T ++ G RTP A + TP A + RT + +
Sbjct: 472 N------DKTTSSSAESTEHGERTPLA------NENTTPSPAEPTENRERTANENTTPSP 519
Query: 2339 VGPRSAHAT--------APVNIAGSRTAAAL-----APASLTSARMAPALSGANLTSP-- 2383
GP T +PV +R A +PA T + TS
Sbjct: 520 AGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSA 579
Query: 2384 -------RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPS 2436
R PL A E + + P +R R+ + PS + T +P + PS
Sbjct: 580 EPTEHGERTPL-ANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPS 638
Query: 2437 QSLLPPAQDQPRSPVPSAFSDQSRCLIAQ---TTPVAGSQSLSSGAVATTTSSAGDHNGM 2493
L P ++ R+P + + S + TP+A + S A T +
Sbjct: 639 --LAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN- 695
Query: 2494 LSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS---- 2549
+ P+P P + A + + L +P + R +++ ++SS + + +
Sbjct: 696 -TTPSPAGPTEN-----REMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTP 749
Query: 2550 -SSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT-PAKRKRRS 2607
++ ++S S+ G P+ E PT + E P P P + + R+
Sbjct: 750 FANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERT 809
Query: 2608 SSSSSSSSSSSSSSS----------------------------SSSSSSSSSSSSSSSSS 2639
++ +++ S + + + + ++SSS+ + +
Sbjct: 810 ANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAER 869
Query: 2640 SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR 2699
+ ++ +++ SPA +P ++ E+ ++ P +P ++ + + E+
Sbjct: 870 TPLANENTTSSPA--------EPTENRERTANEKTTQFPAEPTENRESTAN------EKT 915
Query: 2700 RPSPQPSPRDQQSSSSE 2716
P P +++ +++E
Sbjct: 916 TPFPAEPTENREWTANE 932
Score = 52.0 bits (123), Expect = 8e-06
Identities = 64/300 (21%), Positives = 119/300 (39%), Gaps = 39/300 (13%)
Query: 2468 PVAGSQSLSSGAVATTT--SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQ 2525
P+ +Q A +TTT SAG + PAP S + ++TG S +
Sbjct: 194 PMIRNQRSVDPADSTTTHKESAGKKH---ITPAP---KSKINCRKSTTGK---STVTRKS 244
Query: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585
R S S+ +S+SS +++S +SG+S + + +S P + A K T
Sbjct: 245 DKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGT 304
Query: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
P+E+ E T R +S + ++ + + S++ + S + + +++
Sbjct: 305 PEES-------EKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANE 357
Query: 2646 SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL-----RDSRSLSYSPVERRR 2700
+++PSPA +P ++ E + SP +P ++ ++ P E R
Sbjct: 358 NNTPSPA--------EPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENRE 409
Query: 2701 PSPQPSPRDQQSSSSERGSRRGQRGDSRSPS----HKRR----RETPSPRPMRHRSSRSP 2752
+ + + +E G R + SP+ H R TPSP R+P
Sbjct: 410 MTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTP 469
Score = 44.3 bits (103), Expect = 0.002
Identities = 61/396 (15%), Positives = 146/396 (36%), Gaps = 36/396 (9%)
Query: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER---APSPSSRMGQAPS---QSL 2439
P ++ E S + P++ RS P + + + ++ + P+P S++ S +S
Sbjct: 180 PPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKST 239
Query: 2440 LPPAQDQPRSPVPSAFSDQSRCLIAQ---TTPVAGSQSLSSGAVATTTSSAGDHNGMLSV 2496
+ D+ P+ + S + + TT S + + +T+ +
Sbjct: 240 VTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTY 299
Query: 2497 PAPGVPH-SDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
G P S+ E +T A + +E S++ + S + + +++ ++
Sbjct: 300 KTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENN 359
Query: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS- 2614
+ S + +E L PT + E P P R +++ +++
Sbjct: 360 TPSPAEPTENRERTANENTTLSPA-EPTENRERTANENTAPFPAGPTENREMTANENTTL 418
Query: 2615 ---SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK---- 2667
+ +++ +++ S + + +++ +++PSPA+P P + K
Sbjct: 419 FPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSS 478
Query: 2668 -----------PPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSE 2716
P E + SP +P ++ + + E PSP +++++++E
Sbjct: 479 SAESTEHGERTPLANENTTPSPAEPTENRERTAN------ENTTPSPAGPTENRETTANE 532
Query: 2717 RGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
+ + + + TPSP R+P
Sbjct: 533 KTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTP 568
Score = 33.5 bits (75), Expect = 3.0
Identities = 40/211 (18%), Positives = 80/211 (37%), Gaps = 19/211 (9%)
Query: 2470 AGSQSLSSGAVATTTSSAGDHNGMLSVP------APGVPHSDVGEPPASTGAQQPSALAA 2523
A SQ S TT G LS PG+ +S + Q+P L
Sbjct: 79 AASQRYSCQMKGATTFQEYQKTGELSTSDHIFPLTPGLVYSIPFDHIVLHSGQRPPELPK 138
Query: 2524 LQPAKERR-----------SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQP 2572
E++ + + +S + SS+ + + + +S ++G ++
Sbjct: 139 STEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQGKDPMIRN 198
Query: 2573 EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632
+ ++ S T + A ++ P P R+S++ S+ + S + S S+
Sbjct: 199 QRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTL 258
Query: 2633 SSSSSSSSSSSSS--SSSPSPAKPGPQALPK 2661
+S+SS +++S +S S K + P+
Sbjct: 259 DKTSTSSHKTTTSFHNSGNSQTKQKSTSFPE 289
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 123 bits (309), Expect = 2e-27
Identities = 302/1394 (21%), Positives = 501/1394 (35%), Gaps = 183/1394 (13%)
Query: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHAS---SSPESPKPAPAPGSHREISSSP 457
+ R P E SS+S SS S +++ S PK + +E SSS
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 458 TSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSR 517
+N+ A K HS RS ++AKR + P R P+ R
Sbjct: 247 EPRNK---HAMNPKGHSERSDTNEKRSVD-SSAKREK-----PVVRPEEIPPVPENRFLL 297
Query: 518 SAQRWGRSRSPQRRGRSRSP----QRPGWSRS-RNTQRRGRSRSARRGRSHSRSPATRGR 572
+ P+ + +P Q+P S+S R + RG R RS S S +
Sbjct: 298 RRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDD 357
Query: 573 SRSRTPARRGRSRSRTPARRR---------SRSRTPTRRRSRSRTPARRGRSRSRT---- 619
S S TP R A R + P R R+ ++R RS S
Sbjct: 358 S-SETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYS 416
Query: 620 --PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR 677
R S R+ + + + + R + + R P+ S+S T +
Sbjct: 417 DLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMK 476
Query: 678 SGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTS 737
S R R+ S + +R S+S V+ +HS R +S S S + SR+
Sbjct: 477 SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSR 536
Query: 738 QRRSRSNSSPEMKKSRISSR---RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP 794
S+ S KSR SS+ R R+ SPR A LS + P + +
Sbjct: 537 TASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTAS-------QLSENKPVKTEPLRATM 589
Query: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPK--QKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852
++ + QP P S SPPP + + P + S+ + P Q
Sbjct: 590 AQNENVVVQPVVAENIPV--IPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQ 647
Query: 853 GSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS-CSGSSPPRVKSSTPPRQSPSR 911
+ + E T S + + E T S++S S S PR +S + +S SR
Sbjct: 648 STYSLANIKE---TGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSR 704
Query: 912 SSSPQPKVKAIISPRQRSHSGSS-SPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHS 970
S + + +++ S RS S SS S S ++ + + RS S + S+ + R R S
Sbjct: 705 SYT---RSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRS 761
Query: 971 G-----------SSSPDTKVKPETPPRQSHSGSISPYPKVKAQ---TPPGPSLSGSKSPC 1016
SSS + + + + S + Y + ++ + S +
Sbjct: 762 SGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQS 821
Query: 1017 PQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEV 1076
QEK K ++ G + S E + + + DH + S P+
Sbjct: 822 AQEKEKQGQMERTHNKQEKNRGEEKSKSERE----CPHSKKRTLKENLSDHLRNGSKPKR 877
Query: 1077 R-----QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGM 1131
+ + SES S + ++ S S E S S P KS
Sbjct: 878 KNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKS-- 935
Query: 1132 SPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFP 1191
S ++S P D N S+ T+ S + + E+ P QK K
Sbjct: 936 --------STNTSLP--DDNGAWKSSKQRTSTSDSEGSCSNSENNRGKP--QKHKHGSKE 983
Query: 1192 VQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQ 1251
R + V K+ L+ ++ A + L ++EE ++ + ++E +
Sbjct: 984 NLKREHTKKV-KEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEK 1042
Query: 1252 ILSHLSSELKEMSTSNFESSPE----VEERPAVSLTLDQSQSQASLEAVEVPSMASSWGG 1307
+S + +K+ +SS E + VS LDQ
Sbjct: 1043 KVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQ--------------------- 1081
Query: 1308 PHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDP 1367
F+ + +LS SP N+ + +N V+E + + L+TD
Sbjct: 1082 --FTKDDSKLSISPTALNTEENVACLQN------------IQHVEESVPNGVEDVLQTDD 1127
Query: 1368 SLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEM 1427
++++ + SP VE+ N + +P ++ V ++ + P+
Sbjct: 1128 NMEI---------CTPDRSSPAKVEETSPLGNARLDTPDINIV-----LKQDMATEHPQA 1173
Query: 1428 KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487
+ + S+ G +D S + + +G S G K++ + P +
Sbjct: 1174 EVVKQESSMSESKVLGEVGKQDSSS--ASLASAGESTGKKEVAEKSQINLIDKKWKP-LQ 1230
Query: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
+ P + + S+ E+ P+ + G + K + R GS + +V
Sbjct: 1231 GVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSK--------NKVRPGSLFD-EV 1281
Query: 1548 KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDK 1607
+ +A R + +S + +TP R + DS+SR SP RSRS S + + +
Sbjct: 1282 RKTARLNRRPRNQ---ESSSDEQTPSR---------DDDSQSR-SPSRSRSKSETKSRHR 1328
Query: 1608 PRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT 1667
R+ + S S S + R+ R G S+GR S SSS S H SR+
Sbjct: 1329 TRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRS--RSSSYRSYKSHRTSSRS 1386
Query: 1668 ARRGSRSSPEPKTK--------SRTPPRRRSSRSSPELTRKARLSRRSRSASS-SPETRS 1718
R S P +++ SR+ R RS RS R +RRSRS S ++ S
Sbjct: 1387 RSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSD-SYHRGRSYNRRSRSCRSYGSDSES 1445
Query: 1719 RTPPRHRRSPSVSS 1732
H RSPS SS
Sbjct: 1446 DRSYSHHRSPSESS 1459
Score = 121 bits (304), Expect = 8e-27
Identities = 324/1433 (22%), Positives = 522/1433 (36%), Gaps = 214/1433 (14%)
Query: 558 RRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617
R+ +HS + S S + + +RRR R P +RS+ R R+ S S
Sbjct: 189 RKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKR---RKEASSS 245
Query: 618 RTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT--PARRGRSRSRTPARRGRSRSRTPA 675
P R +P RS + +RS S ++ P R P R R P
Sbjct: 246 EEP--RNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPV 303
Query: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
+ + P + P +S R + RG TP R RS S S+ + S
Sbjct: 304 V-TAEPEPKIPDVAPIVSDQKPSVSKS-GRKIKGRGTIRYHTPPR-SRSCSESDDDDSSE 360
Query: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQ-KSQTPP 794
T P K+ R R S + +LS PC + ++
Sbjct: 361 TP---------PHWKEEMQRLRAYRPPSGEKWSKGDKLS--------DPCSSRWDERSLS 403
Query: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS 854
+RSRS S + R S ++K K + H + T R+
Sbjct: 404 QRSRSWSYNGYYSDLSTARHSGHHKK---RRKEKKVKHKKKGKKQKHCRRHKQTKKRR-- 458
Query: 855 ITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS 914
I P E S + RR +SS D E SR+ S S S KS + S + SS
Sbjct: 459 ILIPSDIESSKSSTRR--MKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSR 516
Query: 915 PQPKVKAII------SPRQRSHSGSSSPSPSRVTSRTTPR---RSRSVSPCSNVESRLLP 965
+ K+ S R R+ S SSS S SR SR++ + R R+ S+L
Sbjct: 517 DSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQL-- 574
Query: 966 RYSHSGSSSPDTKVKP-ETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDS 1024
S + K +P Q+ + + P V A+ P LS S P + +
Sbjct: 575 ------SENKPVKTEPLRATMAQNENVVVQP---VVAENIPVIPLSDSPPPSRWKPGQKP 625
Query: 1025 LVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP 1084
S + A P +Y S +K +S H+ + +S + ++S+
Sbjct: 626 WKPSYERIQEMKAKTTHLLPIQSTY---SLANIKETGSSSSYHKREKNSESDQSTYSKYS 682
Query: 1085 SLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQ----- 1139
S+S SP RSRS S + SRS R R S+ +S S SR +
Sbjct: 683 DRSSES--SP---RSRSRSSRSRSYSRSYTRS-RSLASSHSRSRSPSSRSHSRNKYSDHS 736
Query: 1140 --SDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPE 1197
S SSSY ++ S+ R S +K ++ ++ +++S K+ V+ R
Sbjct: 737 QCSRSSSYTSISSDDGRRAKR-RLRSSGKKNSVSHKKHSSSSEKTLHSKY----VKGRDR 791
Query: 1198 SSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLS 1257
SS V K + RS S ++++ + S+Q++E +E++
Sbjct: 792 SSCVRKYS-----ESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNK--------- 837
Query: 1258 SELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKEL 1317
+E + +S E E + TL ++ S +H
Sbjct: 838 ---QEKNRGEEKSKSERECPHSKKRTLKENLS-----------------------DHLRN 871
Query: 1318 SNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKE-QST 1376
+ P R+N GS + ++ N+ + ++ PS D +E ++T
Sbjct: 872 GSKPKRKNYAGSKWDSESNSERDVTKNS----------------KNDSHPSSDKEEGEAT 915
Query: 1377 RSSGHSSSELSPDAVEKAGMSSNQSI---SSPVLDAVPRTPSRERSSSASSPEMKDGLPR 1433
S SE+ S+N S+ + + RT + + S S+ E G P+
Sbjct: 916 SDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQ 975
Query: 1434 TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT--------PSRGRSECDSSPE 1485
+ + GS L+ + L G P+ P E + +
Sbjct: 976 ----KHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEID 1031
Query: 1486 PKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL 1545
K + Q + + S ++ + + L ++ S + L Q ++ S +L
Sbjct: 1032 DKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDS--KL 1089
Query: 1546 DVKPSASPQERSESDSSPDSKAKTRTP--LRQRSRSGSSPEVDSKSRLSPRRSRSGS--- 1600
+ P+A E + + + P + ++ + E+ + R SP + S
Sbjct: 1090 SISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLG 1149
Query: 1601 -----SPEV-----KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR-GPSP 1649
+P++ +D P+A+ S S S S G G
Sbjct: 1150 NARLDTPDINIVLKQDMATEHPQAEVVKQES--------------SMSESKVLGEVGKQD 1195
Query: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
S+S S+ E K A + + + K K P + + ++P + + +
Sbjct: 1196 SSSASLASAGESTGKKEVAEKSQINLIDKKWK---PLQGVGNLAAPNAATSSAVE--VKV 1250
Query: 1710 ASSSPET-----RSRTPPRHRRSPSVSSPEPAEKSRSSRR-RRSASSPRTKTTSRRGRSP 1763
++ PE R +++ P E + +R +RR R SS +T SR S
Sbjct: 1251 LTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQ 1310
Query: 1764 SPKP-RGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
S P R +S ++SR + RS S STS R RS SRSR G++S
Sbjct: 1311 SRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSR-------SRGWYS 1363
Query: 1823 RSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPL 1882
R R SR+SS R RT +SR RSRS +S P RSRS + + RSRSR+
Sbjct: 1364 RGRTR---SRSSSYRSYKSHRT--SSRSRSRS-SSYDPHSRSRSYTYDSYYSRSRSRSR- 1416
Query: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRS 1935
S+R RRSRS RS S R S R+P + R S
Sbjct: 1417 -SQRSDSYHRGRSYNRRSRS------CRSYGSDSESDRSYSHHRSPSESSRYS 1462
Score = 108 bits (270), Expect = 7e-23
Identities = 195/840 (23%), Positives = 301/840 (35%), Gaps = 137/840 (16%)
Query: 169 KPYSLVRESSSSRSPTPKQK----KKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE-SE 223
+PY+ VR T K KK+KK S+SSS +SS + + E S
Sbjct: 163 RPYADVRVIDCGVLATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSR 222
Query: 224 SKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAA 283
+K K R PK KR KKR++ S++ P+++ H + SDT+ RS ++
Sbjct: 223 RRKHKRR---PKVKR---SKKRRKEASSSEEPRNK--HAMNPKGHSERSDTNEKRSVDSS 274
Query: 284 AKTHTTALAGRSPSPASGRRG--EGDAPF--SEP--------GTTSTQRPSSPETATK-- 329
AK + P R D P +EP S Q+PS ++ K
Sbjct: 275 AKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIK 334
Query: 330 --------QPSSPYEDKDKDKKEKSATRP-------------SPSPERSSTGPEPPAP-- 366
P + D + S T P PS E+ S G + P
Sbjct: 335 GRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCS 394
Query: 367 ---------------------TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405
+ L RH G + + + R +
Sbjct: 395 SRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQT 454
Query: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHG 465
K +P S ESS S + K S S S + S R+ S S S
Sbjct: 455 KKRRILIP--SDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLT 512
Query: 466 RAKRD----KSHSHTPSRRMGRSRSPATA---KRGRSRSRTPTKRGHSR--SRSPQWRRS 516
+ RD KSHS + SR RSR+ + + R RS+SR+ +K GH + S+SP+ S
Sbjct: 513 HSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTAS 572
Query: 517 RSAQRWGRSRSPQRRGR---------------------SRSPQRPGWSRSRNTQRRGRSR 555
+ ++ P R S SP W + + R
Sbjct: 573 QLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYER 632
Query: 556 SARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615
+ + G S S + S S T + R+ RS
Sbjct: 633 IQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRS 692
Query: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPA 675
RSR+ SR+RS R +RSRS A S SRSR+P+ R SR++ SRS +
Sbjct: 693 RSRS-----SRSRSYSRSYTRSRSLA--SSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYT 745
Query: 676 RRS---GRSRSRTPARRGRSRSRTPRRGRSRSRSLVR----RGRSHSRTPQRRGRSGSSS 728
S GR R G+ S + ++ S S + +GR S ++ S SS
Sbjct: 746 SISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSL 805
Query: 729 ERKNKSRTS-----QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783
+ + S S Q +M+++ ++R +S+ + S +R+L +
Sbjct: 806 DYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENL 865
Query: 784 PCPKQKSQTPPRRSRSGS--SQPKAKSRTPPRRSRSSSSP-PPKQKSKTPSRQSHSSSSP 840
+ P R++ +GS R + S++ S P K++ + S S
Sbjct: 866 SDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEI 925
Query: 841 HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVK 900
H KVK T +++ + P ++SS + S + S SCS S R K
Sbjct: 926 HIKVKPTT----------KSSTNTSLPDDNGAWKSS--KQRTSTSDSEGSCSNSENNRGK 973
Score = 102 bits (253), Expect = 7e-21
Identities = 232/1115 (20%), Positives = 388/1115 (34%), Gaps = 194/1115 (17%)
Query: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRR-------------SESSSPRRERKKSS 213
PP+ S S TP K++ ++ R R S+ S R + + S
Sbjct: 344 PPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLS 403
Query: 214 KKKK-------------------HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA 254
++ + H+ + KK KH+ K K + K+ K+ R P+
Sbjct: 404 QRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPS 463
Query: 255 PKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPS----PASGRRGEGDAPF 310
+ +S++ SS D RS SRS++ +H ++ S S +S D+
Sbjct: 464 --DIESSKSSTRRMKSSCDRERS-SRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYR 520
Query: 311 SEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLL 370
S+ + S R SS + SS + K + S S R P L
Sbjct: 521 SKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSS------SKSGHRKRASKSPRKTASQL 574
Query: 371 AERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPS------ 424
+E +PL T E V P E +P S+S PPS
Sbjct: 575 SENKPVKTEPLRATMAQNENV-----------VVQPVVAENIPVIPLSDSPPPSRWKPGQ 623
Query: 425 -PQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRS-HGRAKRDKSHSHTPSRRMG 482
P R ++ P ++ + T + S H R K +S T S+
Sbjct: 624 KPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSD 683
Query: 483 RSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS-AQRWGRSRSPQRRGRSRSPQRPG 541
RS + RSRSR+ R +SRS + RSRS A RSRSP R SR+
Sbjct: 684 RSSESSP----RSRSRSSRSRSYSRS----YTRSRSLASSHSRSRSPSSRSHSRNKYSDH 735
Query: 542 WSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTR 601
SR++ S S+ GR R + G+ S + + S +T +
Sbjct: 736 SQCSRSSSY--TSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYV------- 786
Query: 602 RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG---RSRSRTPARRGRS 658
+ R R+ R S SR+ S + + ++S + G R+ ++ RG
Sbjct: 787 -KGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEE 845
Query: 659 RSRTPARRGRSRSRTPARRSG---RSRSRTPARRGRSRSRTPRRGRS-RSRSLVRRGRSH 714
+S++ S+ RT R+ S+ P R+ + S+ S R + + SH
Sbjct: 846 KSKSERECPHSKKRTLKENLSDHLRNGSK-PKRKNYAGSKWDSESNSERDVTKNSKNDSH 904
Query: 715 SRTPQRRGRSGSSSER---------KNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP 765
+ + G + S SE K +++S S + + K S+ + S S S
Sbjct: 905 PSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSC 964
Query: 766 RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPP-- 823
+ +R ++ GS K++ + G K K+ P+R ++ PP
Sbjct: 965 SNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKA---PKRKQAFHWQPPLE 1021
Query: 824 --KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPEL 881
+++ + + + S KV + +I + + + + S D +
Sbjct: 1022 FGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQ 1081
Query: 882 KSRTPSRHSCSGS------------------------------SPPRVKSSTPPRQSPSR 911
++ S+ S S + + ++ TP R SP++
Sbjct: 1082 FTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAK 1141
Query: 912 SSSPQPKVKAIIS----------------PRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP 955
P A + P+ SS S S+V + S S S
Sbjct: 1142 VEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASL 1201
Query: 956 CSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSP 1015
S ES S + + P Q +P + + S
Sbjct: 1202 ASAGES---TGKKEVAEKSQINLIDKKWKPLQGVGNLAAP--------------NAATSS 1244
Query: 1016 CPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV---SSLQLKGQSQTSP------- 1065
+ K ++ + P L + K+ PG + V + L + ++Q S
Sbjct: 1245 AVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPS 1304
Query: 1066 -DHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIR-QDRGEFSA 1123
D S + SP +S SE+ S S RSRS S + SRS R + RG +S
Sbjct: 1305 RDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYS- 1363
Query: 1124 SPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSR 1158
+ R +S SSSY + S+ +SR
Sbjct: 1364 -----------RGRTRSRSSSYRSYKSHRTSSRSR 1387
Score = 97.4 bits (241), Expect = 2e-19
Identities = 155/658 (23%), Positives = 252/658 (38%), Gaps = 61/658 (9%)
Query: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553
+ R + S ++ + S SES ++ + R +R + S++ + S+S
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
+ R++ +P + +RS + VDS ++ R P V + R
Sbjct: 247 EPRNKHAMNPKGHS-------ERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRR 299
Query: 1614 AQSGSDSSPEPKAPAPRAL-----PRRSRSGSSSKGRGP-----SPEGSSSTES----SP 1659
+ PEPK P + P S+SG KGRG P S +ES S
Sbjct: 300 DMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSS 359
Query: 1660 EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
E PP + + R+ P + + + S S ++ LS+RSRS S +
Sbjct: 360 ETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERS-LSQRSRSWSYNGYYSDL 418
Query: 1720 TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR 1779
+ RH E K + +++ +T RR PS ++ S+S +RR
Sbjct: 419 STARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSD----IESSKSSTRR 474
Query: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
K+ R +RS S S S R S+ + + + SR R +S S R
Sbjct: 475 MKSSCDR--ERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGS 532
Query: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
RSRT S SRSR+ +SRS +S + HR+ S++P R++ S+ S +
Sbjct: 533 SRSRTASKSSSHSRSRS------KSRS-SSKSGHRKRASKSP----RKTASQLSENKPVK 581
Query: 1900 SRSRTSVTRRRSRSRASPVSRRR----SRSRTPPVTRRRSRSRT-PTTRRRSRSRTPPVT 1954
+ + + PV S +PP +R + + + R + T
Sbjct: 582 TEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTT 641
Query: 1955 RRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT 2014
T + + +S +R S + T + R+S + RSRSR+S
Sbjct: 642 HLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSE-SSPRSRSRSS--- 697
Query: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPA 2074
RSRS + R +RSR+ RSRS S + R S + +R + S
Sbjct: 698 --RSRSYS----RSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDD 751
Query: 2075 IRRRSASGSSSDRSRSATPPATRNHSGSRTPPV----ALNSSRMSCFSRPSMSPTPLD 2128
RR SS + S + + HS S + R SC + S S + LD
Sbjct: 752 GRRAKRRLRSSGKKNSV---SHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLD 806
Score = 94.7 bits (234), Expect = 1e-18
Identities = 300/1392 (21%), Positives = 500/1392 (35%), Gaps = 221/1392 (15%)
Query: 670 RSRTPARRSGRSRSRTPARRGRSRSRTP-RRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728
+ + P G S + S S + RSR R RR + R+ +RR + SS
Sbjct: 188 KRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKV-KRSKKRRKEASSSE 246
Query: 729 ERKNKSRTSQRRSRSNSSPEMKKSRISS-RRSRSLSSPRS---KAKSRLSLRRSLSGSSP 784
E +NK + + S K+S SS +R + + P ++R LRR + +
Sbjct: 247 EPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTA 306
Query: 785 CPKQK--------SQTPPRRSRSG---SSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR- 832
P+ K S P S+SG + + TPPR SRS S S+TP
Sbjct: 307 EPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPR-SRSCSESDDDDSSETPPHW 365
Query: 833 ----QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR 888
Q + P K + S + +E+S++ + RS + +L + S
Sbjct: 366 KEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSG 425
Query: 889 HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948
H +VK ++ Q K + I+ P S SS+ R
Sbjct: 426 HHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSS 485
Query: 949 RSRSVSPC-----------SNVESRLLPRY-------SHSGSSSPDTKVKPETPPRQSHS 990
RS S+S +V+S L SHS S S + SHS
Sbjct: 486 RSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHS 545
Query: 991 GSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYF 1050
S S K ++ + G SKSP K+ L ++ P VK+
Sbjct: 546 RSRS---KSRSSSKSGHRKRASKSP---RKTASQLSENKP--------VKTEPLRATMAQ 591
Query: 1051 GVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELAS 1110
+ + ++ P S P R + P S + ++ P+ S
Sbjct: 592 NENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYS 651
Query: 1111 RSPIRQDRGEFSASPMLKSGMSPEQSRFQ--SDSSSYPTVDSNSLLGQSRLETAESKEKM 1168
+ I++ G S+ + +QS + SD SS + S S +SR +
Sbjct: 652 LANIKET-GSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710
Query: 1169 ALPPQEDATASPPRQ---KDKFSPFPVQDRPES--SLVFKDTLRTPPRERSGAGSSPETK 1223
+L + SP + ++K+S R S S+ D R R RS + +
Sbjct: 711 SLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSH 770
Query: 1224 EQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLT 1283
+++S SS ++ L K + + + + S S+ ++ S E+ +V T
Sbjct: 771 KKHS----SSSEKTLHSKYVKGRDRSSCVRKYSESR----SSLDYSSD---SEQSSVQAT 819
Query: 1284 LDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEM 1343
+ + + + G S +E +S R RN +
Sbjct: 820 QSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKN 879
Query: 1344 NTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSIS 1403
G S+ + N E D + + K S SS E + D S +S
Sbjct: 880 YAG--SKWDSESNS------ERDVTKNSKNDSHPSSDKEEGEATSD--------SESEVS 923
Query: 1404 SPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSS 1463
+ P T S S++ S P+ +G ++ +R+ + S +GS + S ++
Sbjct: 924 EIHIKVKPTTKS---STNTSLPD-DNGAWKSSKQRTSTSDS----EGSCSNSENN----- 970
Query: 1464 PGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERS------ 1517
RG+ + + L + + + + + K P+R+++
Sbjct: 971 -----------RGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPP 1019
Query: 1518 -----GSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESD--SSPDSKAKTR 1570
E +D K V + + + S +K + E+S + S
Sbjct: 1020 LEFGEEEEEEIDDKQVTQE---SKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVS 1076
Query: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE-VKDKPRAAPRAQSGSDSSPEPKAPAP 1629
+ L Q ++ DSK +SP + + +++ +G + +
Sbjct: 1077 SDLDQFTKD------DSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNME 1130
Query: 1630 RALPRRSRSGSSSKGRGPSPEGSSSTES-----------SPEHPPKSRTARRGSRSSPEP 1678
P RS S +K SP G++ ++ + EHP + S S E
Sbjct: 1131 ICTPDRS---SPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMS--ES 1185
Query: 1679 KTKSRTPPRRRSSRS---SPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735
K + SS S + E T K ++ +S+ + + + +P+ ++
Sbjct: 1186 KVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATS-- 1243
Query: 1736 AEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQ 1795
SA + TT P KP+GL+ ++ + R GS
Sbjct: 1244 -----------SAVEVKVLTTV-----PEMKPQGLRIEIK---------SKNKVRPGSLF 1278
Query: 1796 STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS---RTSSRRRRGRSRTPPTSRKRS 1852
R+ R +R P QESS +T SR +SR+P SR RS
Sbjct: 1279 DEVRKTARL-----------------NRRPRNQESSSDEQTPSRDDDSQSRSP--SRSRS 1319
Query: 1853 RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSR 1912
+S T R R+R+ +H RSRSR+ S RSRS + RSRSR +R R+R
Sbjct: 1320 KSETK----SRHRTRSVSYSHSRSRSRSS-TSSYRSRSYS------RSRSRGWYSRGRTR 1368
Query: 1913 SRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS 1972
SR+S +S RT +R RS S P +R RS + +R RSRSR ++R
Sbjct: 1369 SRSSSYRSYKSH-RTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSR----SQRSDSY 1423
Query: 1973 RTSPITRRRSRS 1984
RRSRS
Sbjct: 1424 HRGRSYNRRSRS 1435
Score = 94.7 bits (234), Expect = 1e-18
Identities = 299/1388 (21%), Positives = 484/1388 (34%), Gaps = 209/1388 (15%)
Query: 786 PKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVK 845
P + + S SS+ ++S RSR + ++ R+ +SSS P+ K
Sbjct: 192 PTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNK 251
Query: 846 SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP 905
P+ S E+S T ++RS +SS E P PP ++
Sbjct: 252 HAMNPKGHS-------ERSDTNEKRSV-DSSAKREKPVVRPEE------IPPVPENRFLL 297
Query: 906 RQS-PSRSSSPQPK---VKAIISPRQRSHSGSSSPSPSRVTSRT-TPRRSRSVSPCSNVE 960
R+ P ++ P+PK V I+S ++ S S S R T R TP RSRS S + +
Sbjct: 298 RRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDD 357
Query: 961 SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSL--SGSK--SPC 1016
S ETPP +++A PP G K PC
Sbjct: 358 SS-------------------ETPPHWKEE-----MQRLRAYRPPSGEKWSKGDKLSDPC 393
Query: 1017 PQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKG-----QSQTSPDHRSDT 1071
+ SL Q S Y +S+ + G + + H+
Sbjct: 394 SSRWDERSLSQR-----------SRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKG 442
Query: 1072 SSPEVRQSHSESPS----LQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML 1127
+ + H ++ + S ++S R SS E +SRS S
Sbjct: 443 KKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHS-SKRDWS 501
Query: 1128 KSGMSPEQSRFQSDSSSYPTVDSNSLL--GQSRLETAESKEKMALPPQEDATASPPRQKD 1185
KS + S S SY + + G SR TA + + ++S +
Sbjct: 502 KSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRK 561
Query: 1186 KFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKS 1245
+ S P + S L ++T P T QN + E + V+ S
Sbjct: 562 RASKSP--RKTASQLSENKPVKTEPLRA--------TMAQNENVVVQPVVAENIPVIPLS 611
Query: 1246 EEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSW 1305
+ P S K S ++E A + L QS SL ++ +SS+
Sbjct: 612 DSPP-------PSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSY 664
Query: 1306 GGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLET 1365
+ E + + S + S S R+ + ++ +
Sbjct: 665 HKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRS-------------RS 711
Query: 1366 DPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSP 1425
S + +S S HS ++ S D + + SS SISS D R R RSS
Sbjct: 712 LASSHSRSRSPSSRSHSRNKYS-DHSQCSRSSSYTSISS---DDGRRAKRRLRSS----- 762
Query: 1426 EMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPE 1485
G + S + S SS + HS R S RS D S +
Sbjct: 763 ----GKKNSVSHKKHSSSSE--------KTLHSKYVKGRDRSSCVRKYSESRSSLDYSSD 810
Query: 1486 PKA----LPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541
+ Q+ + + + +NK Q + G E S K+ P ++
Sbjct: 811 SEQSSVQATQSAQEKEKQGQMERTHNK----QEKNRGEEKS---KSERECPHSKKRTLKE 863
Query: 1542 SQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSS 1601
+ ++ + P+ ++ + S DS++ + + + S++ S P D + + S S S
Sbjct: 864 NLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVS 923
Query: 1602 P-EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGS--------SSKGRGPSPEGS 1652
+K KP S + S P+ + R S S S +++G+ +
Sbjct: 924 EIHIKVKPTTK---SSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHG 980
Query: 1653 SSTESSPEHPPKSRTARRGSRSSPE--PKTKSR---TPPRRRSSRSSPELTRKARLSRRS 1707
S EH K + +G + PK K PP E+ K ++++ S
Sbjct: 981 SKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDK-QVTQES 1039
Query: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK- 1766
+ S + T + SS E + S TK S+ SP+
Sbjct: 1040 KEKKVSEN--NETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALN 1097
Query: 1767 ------------------PRGLQR-----------SRSRSRREKTRTTR-----RRDRSG 1792
P G++ + RS K T R D
Sbjct: 1098 TEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARLDTPD 1157
Query: 1793 SSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRS 1852
+ + ++ V ++ S ++ S ++S G S ++S
Sbjct: 1158 INIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKS 1217
Query: 1853 RSRTSPAPWK---------RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
+ WK + S A + + P + + R ++ R S
Sbjct: 1218 QINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSL 1277
Query: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP 1963
R+ +R P ++ S P S+SR+P+ RSRS++ +R R+RS +
Sbjct: 1278 FDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPS---RSRSKSETKSRHRTRSVSY 1334
Query: 1964 PVTRRRSRSRTSPITRR---RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS 2020
+R RSRS TS R RSRSR +R R+RSR+S +S RTS +R RS S
Sbjct: 1335 SHSRSRSRSSTSSYRSRSYSRSRSR-GWYSRGRTRSRSSSYRSYKSH-RTSSRSRSRSSS 1392
Query: 2021 RTPPAIRRRSRSRTPLLPRKRSRSRSPLA---IRRRSRSRTPRTARGKRSLTRSPPAI-R 2076
P + R RS + R RSRSRS + R RS +R R+ R S + S +
Sbjct: 1393 YDPHS-RSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSH 1451
Query: 2077 RRSASGSS 2084
RS S SS
Sbjct: 1452 HRSPSESS 1459
Score = 89.4 bits (220), Expect = 5e-17
Identities = 151/635 (23%), Positives = 242/635 (38%), Gaps = 77/635 (12%)
Query: 154 QRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRR---SESSSPRRERK 210
Q + R ++ E P+S R + S + K K+K+ SES+S R K
Sbjct: 838 QEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTK 897
Query: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAP------KSRRAHRST 264
S S+ E + S + S+ K K +S + T P KS + ST
Sbjct: 898 NSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTST 957
Query: 265 SADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRR--GEGDAPFSEPGTTSTQRPS 322
S S S++ +R + K + R + + G+ D P
Sbjct: 958 SDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQ 1017
Query: 323 SPETATKQPSSPYEDKD--KDKKEKSAT-----------RPSPSPERSSTGPEPPAPTPL 369
P ++ +DK ++ KEK + + S E +G
Sbjct: 1018 PPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSS 1077
Query: 370 LAERHGGSPQPLATTP--LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES--SPPSP 425
++ L+ +P L+ E + + S P E + Q+ + +P
Sbjct: 1078 DLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRS 1137
Query: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTP-----SRR 480
P KV +SP P + + +++ K++ S S + ++
Sbjct: 1138 SPAKVEE---TSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQ 1194
Query: 481 MGRSRSPATAKRGRSRSRTPTK-------------RGHSRSRSPQWRRSRSAQRWGRSRS 527
S S A+A + K +G +P S + + +
Sbjct: 1195 DSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTV 1254
Query: 528 PQRRG-------RSRSPQRPG--WSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP 578
P+ + +S++ RPG + R T R R + S ++P+ S+SR+P
Sbjct: 1255 PEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSP 1314
Query: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRR-RSRS 637
+R RS+S T +R R+RS + + RSRSR+ RSRS + RSR+R R R+RS
Sbjct: 1315 SR-SRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYS----RSRSRGWYSRGRTRS 1369
Query: 638 RSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR--------R 689
RS + RS +S + R RS S P SRSR+ S SRSR+ +R R
Sbjct: 1370 RSSSYRSYKSHRTSSRSRSRSSSYDP----HSRSRSYTYDSYYSRSRSRSRSQRSDSYHR 1425
Query: 690 GRSRSRTPRRGRS-RSRSLVRRGRSHSRTPQRRGR 723
GRS +R R RS S S R SH R+P R
Sbjct: 1426 GRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSR 1460
Score = 83.2 bits (204), Expect = 3e-15
Identities = 160/695 (23%), Positives = 249/695 (35%), Gaps = 83/695 (11%)
Query: 1372 KEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL 1431
+++ T S G SS S + E + S + S R R S K+
Sbjct: 189 RKKPTHSEGSDSSSNSSSSSESSSESELEHERSR-----RRKHKRRPKVKRSKKRRKEAS 243
Query: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMK------DIPRTPS------RGRSE 1479
R + + G + S T + S+ S+ K +IP P R
Sbjct: 244 SSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPV 303
Query: 1480 CDSSPEPKALPQTPRPRSRSPSSPELNNKCL--------TPQRERSGSESSVDQKTVART 1531
+ PEPK P + PS + K TP R RS SES D + T
Sbjct: 304 VTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSS--ET 361
Query: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK--- 1588
P + + PS + + S P S L QRSRS S S
Sbjct: 362 PPHWKEEMQRLRAYR-PPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLST 420
Query: 1589 SRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
+R S + +VK K + + + + +P S SS R S
Sbjct: 421 ARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRIL---IPSDIESSKSSTRRMKS 477
Query: 1649 P---EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
E SS + S H +++R S + S T R S RS +R S
Sbjct: 478 SCDRERSSRSSSLSSH----HSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSS 533
Query: 1706 RSRSAS-SSPETRSRTPPR------HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758
RSR+AS SS +RSR+ R HR+ S S + A S+ S + + P T ++
Sbjct: 534 RSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTA--SQLSENKPVKTEPLRATMAQ 591
Query: 1759 RGR----------------SPSPKP-------RGLQRSRSRSRREKTRTTRRRDRSGSSQ 1795
S SP P + + S R + K +TT S+
Sbjct: 592 NENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQ-STY 650
Query: 1796 STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR 1855
S + ++ S S R + S + S SS +S R R SR+ SR +RSR
Sbjct: 651 SLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710
Query: 1856 TSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA 1915
+ + RSRS +S + R S SR S + S RR++ R RS +
Sbjct: 711 SLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRL-----RSSGKK 765
Query: 1916 SPVSRRRSRSRTPPVTRR---RSRSRTPTTRRRSRSRTP-PVTRRRSRSRTPPVTRRRSR 1971
+ VS ++ S + + R R+ R+ S SR+ + +S + +
Sbjct: 766 NSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEK 825
Query: 1972 SRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2006
+ + R ++ + + R P +++R+
Sbjct: 826 EKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRT 860
Score = 76.3 bits (186), Expect = 4e-13
Identities = 139/576 (24%), Positives = 203/576 (35%), Gaps = 103/576 (17%)
Query: 1600 SSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSP-EGSSSTESS 1658
S +V +K R P GSDSS S S SSS+ S E S
Sbjct: 180 SIKDVFEKKRKKPTHSEGSDSS--------------SNSSSSSESSSESELEHERSRRRK 225
Query: 1659 PEHPPK---SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE 1715
+ PK S+ R+ + SS EP+ K P+ S RS R S + PE
Sbjct: 226 HKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPE 285
Query: 1716 TRSRTPPRH---RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR 1772
P RR V + EP K S P + R+ K RG R
Sbjct: 286 EIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRK-----IKGRGTIR 340
Query: 1773 SRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR-----SRSRVTRRRRGGSGYHSRSPAR 1827
+ R + D S + QR R S + ++ + SR R
Sbjct: 341 YHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDER 400
Query: 1828 QESSRTSSRRRRGRSRTPPTSR-----KRSRSRTSPAPWKRSRSRASPATHRRSRSRTPL 1882
S R+ S G T+R K+ R K+ + + H++++ R L
Sbjct: 401 SLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRIL 460
Query: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTT 1942
I S++S R ++S R RS SR+S +S S R + + +S +
Sbjct: 461 IPSDIESSKSST-----RRMKSSCDRERS-SRSSSLSSHHSSKRDWSKSDKDVQSSLTHS 514
Query: 1943 RR---RSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999
R RS+S + +R SRSRT S++S +R RS+SR+S + R R+ S
Sbjct: 515 SRDSYRSKSHSQSYSRGSSRSRTA--------SKSSSHSRSRSKSRSSSKSGHRKRASKS 566
Query: 2000 PVTRRRSRSRTSPVTRRRSR------------------------SRTPP----------- 2024
P S PV R S +PP
Sbjct: 567 PRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPW 626
Query: 2025 -----AIRRRSRSRTPLLPRKRSRS--------RSPLAIRRRSRSRTPRTARGKRS--LT 2069
I+ T LLP + + S S +R S + ++ K S +
Sbjct: 627 KPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSS 686
Query: 2070 RSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTP 2105
S P R RS+ S RS + + +HS SR+P
Sbjct: 687 ESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSP 722
Score = 73.2 bits (178), Expect = 3e-12
Identities = 113/479 (23%), Positives = 181/479 (37%), Gaps = 64/479 (13%)
Query: 152 DPQRRAREAKQPAP-EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERK 210
D + +A + KQ +PP + E ++ K+KK S E
Sbjct: 1002 DKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKV----------SENNETI 1051
Query: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA---- 266
K + K +S E KH + T S D+ K + +P + + +
Sbjct: 1052 KDNILKTEKSSEEDLSGKHDTVTVSS---DLDQFTKDDSKLSISPTALNTEENVACLQNI 1108
Query: 267 ------------DSASSSDTSR--SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE 312
D + D + RS+ AK T+ G + R D
Sbjct: 1109 QHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNA------RLDTPDINIVL 1162
Query: 313 PGTTSTQRPSSPETATKQPSSPYEDK---DKDKKEKSATRPSPSPERSSTGPEPPAPT-- 367
+T+ P + KQ SS E K + K++ S+ + + E STG + A
Sbjct: 1163 KQDMATEHPQAE--VVKQESSMSESKVLGEVGKQDSSSASLASAGE--STGKKEVAEKSQ 1218
Query: 368 ---------PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSS 418
PL + +P ++ + + + E P R KS K+ S
Sbjct: 1219 INLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLF 1278
Query: 419 ESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK-RDKSHSHTP 477
+ + + + R+ SS + P+ S S SK+ + R + R S+SH+
Sbjct: 1279 DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSR 1338
Query: 478 SRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS------PQRR 531
SR + S + RSRSR RG +RSRS +R +S + RSRS P R
Sbjct: 1339 SRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSR 1398
Query: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPA 590
RS + +SRSR+ R RS S RGRS++R + S + + R S R+P+
Sbjct: 1399 SRSYT-YDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPS 1456
Score = 60.8 bits (146), Expect = 2e-08
Identities = 97/456 (21%), Positives = 159/456 (34%), Gaps = 62/456 (13%)
Query: 67 ELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRP---------- 116
E + ++ E + E + + V + ++ +P PGQ+P
Sbjct: 576 ENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQE 635
Query: 117 ---------AVTETHQLAELNE--------KKNERLRAAFGISDSYVDGSS-FDPQRRAR 158
+ T+ LA + E K+ + + Y D SS P+ R+R
Sbjct: 636 MKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSR 695
Query: 159 EAKQPAPEPP--KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK 216
++ + + SL S SRSP+ + + K D + S SSS ++
Sbjct: 696 SSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRA 755
Query: 217 KHRSESESKK-----RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASS 271
K R S KK +KH S + K+ K R RS +SR +S D +S
Sbjct: 756 KRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESR-----SSLDYSSD 810
Query: 272 SDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP 331
S+ S ++ +A + R+ + RGE E + + P S + K+
Sbjct: 811 SEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGE------EKSKSERECPHSKKRTLKEN 864
Query: 332 SSPYEDKDKDKKEK----SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLS 387
S + K K S + ER T P + G AT+
Sbjct: 865 LSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGE-----ATSDSE 919
Query: 388 QEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAP 447
E + PT S S LP + + S T S + S+ E+ + P
Sbjct: 920 SEVSEIHIKVKPTTKSSTNTS---LPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQK 976
Query: 448 ---GSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480
GS + T K + + K+DK H P R+
Sbjct: 977 HKHGSKENLKREHTKKVKEKLKGKKDKKHK-APKRK 1011
Score = 49.3 bits (116), Expect = 5e-05
Identities = 48/184 (26%), Positives = 78/184 (42%), Gaps = 7/184 (3%)
Query: 120 ETHQLAELNEKKNERLRAAFGISDSYVDGS-SFDPQRRAREAKQPAPEPPKPYSLVRESS 178
E + A LN + + ++ + S D S S P R +++ + + S S
Sbjct: 1280 EVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRS 1339
Query: 179 SSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK-KKHRSESESKKRKHR-SPTPKS 236
SRS T + + + R R S R R S + K HR+ S S+ R P +S
Sbjct: 1340 RSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRS 1399
Query: 237 KRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSP 296
+ + D RSRS + + +S HR S + S S RS + +++ + RSP
Sbjct: 1400 RSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRS----CRSYGSDSESDRSYSHHRSP 1455
Query: 297 SPAS 300
S +S
Sbjct: 1456 SESS 1459
Score = 48.9 bits (115), Expect = 7e-05
Identities = 84/350 (24%), Positives = 123/350 (35%), Gaps = 25/350 (7%)
Query: 2405 ARSRTPPSAPSQSRMTSE-RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
+RSRT + S SR S+ R+ S S +A +Q PV + + R +
Sbjct: 533 SRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKT---EPLRATM 589
Query: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP-HSDVGEPPASTGAQQP-SAL 2521
AQ V ++ S + + P P + + E A T P +
Sbjct: 590 AQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQST 649
Query: 2522 AALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPS 2581
+L KE SSSS +S S S+ S S S SS S + S
Sbjct: 650 YSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRS 709
Query: 2582 PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
+ A + R P R + S S S SSS +S SS + SS +S
Sbjct: 710 RSLASSHS--RSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNS 767
Query: 2642 SSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRP 2701
S S S K K G RS RK +S SL YS
Sbjct: 768 VSHKKHSSSSEK---------TLHSKYVKGRDRSSCVRKYSES---RSSLDYS-----SD 810
Query: 2702 SPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
S Q S + QS+ + + +R ++ ++ ++ S R H R+
Sbjct: 811 SEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRT 860
Score = 47.4 bits (111), Expect = 2e-04
Identities = 75/292 (25%), Positives = 100/292 (34%), Gaps = 80/292 (27%)
Query: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS---SSSSSSSSSSSGSSSSDSEGS 2566
P+ + + S RSS SSS SS SS S S SS SS DS S
Sbjct: 462 PSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRS 521
Query: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
Q + ++ RS ++S SSS S S S S SS
Sbjct: 522 KSHSQ---------------------------SYSRGSSRSRTASKSSSHSRSRSKSRSS 554
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSPSPAKPGP------------------QALPK-PASPKK 2667
S S +S S ++S S P K P + +P P S
Sbjct: 555 SKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSP 614
Query: 2668 PPPGERRSRSPRKP-----------------------IDSLRDS-RSLSYSPVERRRPSP 2703
PP + + P KP + +++++ S SY E+ S
Sbjct: 615 PPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESD 674
Query: 2704 QPS---PRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Q + D+ S SS R R R S S S+ R R S H SRSP
Sbjct: 675 QSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLAS----SHSRSRSP 722
Score = 45.8 bits (107), Expect = 6e-04
Identities = 39/129 (30%), Positives = 57/129 (44%), Gaps = 15/129 (11%)
Query: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSS-----------SSSSSSSSS 2627
+PS + K + R + + R+R S SSS SS SS SS + SS
Sbjct: 461 IPSDIESSKSSTRRMK----SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSR 516
Query: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRD 2687
S S S S S S SS S + S + ++ K S K +R S+SPRK L +
Sbjct: 517 DSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSE 576
Query: 2688 SRSLSYSPV 2696
++ + P+
Sbjct: 577 NKPVKTEPL 585
Score = 44.7 bits (104), Expect = 0.001
Identities = 48/156 (30%), Positives = 70/156 (44%), Gaps = 3/156 (1%)
Query: 1969 RSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRR 2028
+S+++ P + +T+ + RR +S + SR S +R SRSR+ +
Sbjct: 1267 KSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQ-SRSPSRSRSKSETKS 1325
Query: 2029 RSRSRTPLLPRKRSRSRSPLA-IRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDR 2087
R R+R+ RSRSRS + R RS SR+ R TRS + R S +S R
Sbjct: 1326 RHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSR 1385
Query: 2088 SRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMS 2123
SRS + + HS SR+ SR SR S
Sbjct: 1386 SRSRS-SSYDPHSRSRSYTYDSYYSRSRSRSRSQRS 1420
Score = 40.8 bits (94), Expect = 0.019
Identities = 84/368 (22%), Positives = 117/368 (31%), Gaps = 37/368 (10%)
Query: 2383 PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP--SQSLL 2440
P+V S R +S R + P S+ T+E+ SS + P +
Sbjct: 230 PKVKRSKKRRKEASSSEE--PRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEI 287
Query: 2441 PPAQDQP---RSPVPSAFSDQSRCLIAQTTPVAGSQSLS---SGAVATTTSSAGDHNGML 2494
PP + R +P ++ I P+ Q S SG + H
Sbjct: 288 PPVPENRFLLRRDMPVVTAEPEP-KIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPR 346
Query: 2495 SVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554
S D E P + A P+ E+ S S SS S S S
Sbjct: 347 SRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRS 406
Query: 2555 SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614
S S + S KR K+ ++ + +KRR S
Sbjct: 407 RSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIE 466
Query: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR 2674
SS SS+ SS SS SSS SS SS
Sbjct: 467 SSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRD--------------------------W 500
Query: 2675 SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR 2734
S+S + SL S SY + + S R + +S S SR + S S S R
Sbjct: 501 SKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHR 560
Query: 2735 RRETPSPR 2742
+R + SPR
Sbjct: 561 KRASKSPR 568
Score = 39.7 bits (91), Expect = 0.041
Identities = 45/178 (25%), Positives = 67/178 (37%), Gaps = 15/178 (8%)
Query: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
TP +++ E A+ ++ SS S S SSS+S +S+ S+ +
Sbjct: 1155 TPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVA 1214
Query: 2643 SSSSSSPSPAKPGP-QALPKPASPKKPPPG-----------ERRSRSPRKPIDSLRDSRS 2690
S + K P Q + A+P E + + R I S R
Sbjct: 1215 EKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRP 1274
Query: 2691 LSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748
S R+ PR+Q+SSS E+ R SRSPS R + S RHR+
Sbjct: 1275 GSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSK---SETKSRHRT 1329
Score = 39.3 bits (90), Expect = 0.054
Identities = 51/209 (24%), Positives = 82/209 (39%), Gaps = 46/209 (22%)
Query: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
+++R + S S SSS+SSSSS SSS S ++ E + +R
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSES------------ELEHERSRRR--------- 224
Query: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
+ R P+ +K++R+ +SSS + + + S S ++ S SS+
Sbjct: 225 ---KHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKRE--- 278
Query: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
KP P++ PP P RD ++ P E + P P
Sbjct: 279 -----KP-------VVRPEEIPP------VPENRFLLRRDMPVVTAEP-EPKIPDVAPIV 319
Query: 2708 RDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
DQ+ S S+ G + RG R + R R
Sbjct: 320 SDQKPSVSKSGRKIKGRGTIRYHTPPRSR 348
Score = 38.9 bits (89), Expect = 0.071
Identities = 49/218 (22%), Positives = 76/218 (34%), Gaps = 36/218 (16%)
Query: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV 2579
A +++ E++ + S S SSS+SSSSS SSS S + E S
Sbjct: 177 ATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSS--ESELEHERS------------- 221
Query: 2580 PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639
+ + RP KR++ +SSS + + + S S ++ S SS
Sbjct: 222 -------RRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSS 274
Query: 2640 SSSSSSSSSPSPAKPGPQ-------------ALPKPASPKKPPPGERRSRSPRKPIDSLR 2686
+ P P P+ A P+P P P + S K ++
Sbjct: 275 AKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIK 334
Query: 2687 DSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQR 2724
++ Y R R S S D S + QR
Sbjct: 335 GRGTIRYHTPPRSR-SCSESDDDDSSETPPHWKEEMQR 371
Score = 38.5 bits (88), Expect = 0.092
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 23/113 (20%)
Query: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRS 2690
S S SSS+SSSSS SSS S + RR + R+P
Sbjct: 195 SEGSDSSSNSSSSSESSSESELEH---------------ERSRRRKHKRRP--------K 231
Query: 2691 LSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP 2743
+ S R+ S PR++ + + + S R + RS +RE P RP
Sbjct: 232 VKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRP 284
Score = 38.1 bits (87), Expect = 0.12
Identities = 73/265 (27%), Positives = 92/265 (34%), Gaps = 67/265 (25%)
Query: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE------------------------ 2564
++ SS S S SSS+S +S+G S+ E
Sbjct: 1177 KQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLA 1236
Query: 2565 ----GSSLPVQPEVALKRVPSPTP-------APKEAVREG--------------RP---- 2595
+S V+ +V L VP P K VR G RP
Sbjct: 1237 APNAATSSAVEVKV-LTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQE 1295
Query: 2596 ---PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
E TP+ R S S S S S S S + S + S S S S S S SS+SS S S +
Sbjct: 1296 SSSDEQTPS-RDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYS 1354
Query: 2653 KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQS 2712
+ + + R +S R S SRS SY P R R S
Sbjct: 1355 RSRSRGWYSRGRTRSRSSSYRSYKSHR--TSSRSRSRSSSYDPHSRSRSYTYDS-----Y 1407
Query: 2713 SSSERGSRRGQRGDS--RSPSHKRR 2735
S R R QR DS R S+ RR
Sbjct: 1408 YSRSRSRSRSQRSDSYHRGRSYNRR 1432
Score = 38.1 bits (87), Expect = 0.12
Identities = 55/188 (29%), Positives = 70/188 (37%), Gaps = 21/188 (11%)
Query: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL 2576
Q S+ P+++ S S S S S S S + S + S S S S SS +
Sbjct: 1294 QESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSY 1353
Query: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
R S + GR + + R +S +SS S S SSS S S S + S
Sbjct: 1354 SRSRS-----RGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYY 1408
Query: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY--S 2694
S S S S S S S + RRSRS R RS S+ S
Sbjct: 1409 SRSRSRSRSQRSDSYHRGRSY--------------NRRSRSCRSYGSDSESDRSYSHHRS 1454
Query: 2695 PVERRRPS 2702
P E R S
Sbjct: 1455 PSESSRYS 1462
Score = 36.6 bits (83), Expect = 0.35
Identities = 63/240 (26%), Positives = 90/240 (37%), Gaps = 26/240 (10%)
Query: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471
S+ S+S++ E SS S SL + + V A Q + + P+ G
Sbjct: 1180 SSMSESKVLGEVGKQDSS------SASLASAGESTGKKEV--AEKSQINLIDKKWKPLQG 1231
Query: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSAL--AALQPAKE 2529
+L++ AT SSA + + +VP + + S +P +L + A+
Sbjct: 1232 VGNLAAPNAAT--SSAVEVKVLTTVPE--MKPQGLRIEIKSKNKVRPGSLFDEVRKTARL 1287
Query: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589
R + SSS + S S S S S S SE S V+ S
Sbjct: 1288 NRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRS-------- 1339
Query: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
R T + R R S S S S + S SSS S S +SS S S SSS P
Sbjct: 1340 ----RSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDP 1395
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 123 bits (308), Expect = 3e-27
Identities = 309/1569 (19%), Positives = 564/1569 (35%), Gaps = 237/1569 (15%)
Query: 237 KRKSKDK---KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
KRK+++ + K++R + P S + A++ ++ T R A T+++ L
Sbjct: 62 KRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPR------LASTNSSVLGA 115
Query: 294 RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS 353
PS + + A + G T P P T K + S
Sbjct: 116 DLPS---SMKEKAKAETEKAGKTGNSMPH-PATG---------------KTVANLLSGKS 156
Query: 354 PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLP 413
P +S+ EP A T L++E P V+ S + D S
Sbjct: 157 PRKSA---EPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS--------- 204
Query: 414 QSSSSESS---PPSPQPTKVSRHASSSPESPK--PAPAPGSHREISSSPTSKNRSHGRAK 468
SSS E+ PS +P +V + S+ ESP APAPG ++
Sbjct: 205 -SSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDV--------------- 248
Query: 469 RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP 528
TP + G AK+ S + + S +P RS + ++
Sbjct: 249 -------TPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRS-------QVKAS 294
Query: 529 QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588
++ + R+ P ++ T +G + + P G S+T A + S +
Sbjct: 295 EKILQVRAASAP----AKGTPGKGATPA---------PPGKAGAVASQTKAGKPEEDSES 341
Query: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSR 648
+ S S T +++ A+ S+ A SP R+ + +P ++G +
Sbjct: 342 SSEESSDSEEET-PAAKALLQAKASGKTSQVGAASAPAKESP--RKGAAPAPPGKTGPAV 398
Query: 649 SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708
++ A + S++ + S PA+ ++ +PR+G + +
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA---- 454
Query: 709 RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL-SSPRS 767
P++ G + + + + S+ S + S + +++ + + L SP+
Sbjct: 455 --------PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
Query: 768 KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS-----SSSPP 822
K S + + G+ P P K ++ G + ++S + S ++ P
Sbjct: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
Query: 823 PKQKSKTPSRQSHSSSSP--HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
++KS Q+ +SSP P K+G Q P N +S E S D
Sbjct: 567 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES--------SEESSDSA 618
Query: 881 LKSRTPSRHSCSGSSP----PRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS--- 933
P+ + + + P P+ K + P + + + S+ P +PR+ + S
Sbjct: 619 DSEEAPAAMTAAQAKPALKIPQTK-ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 677
Query: 934 SSPSPSRVTSRTTPRRSRSVSPCSNVE-SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992
SSP+ + T R S S S E + L + S +VK + P + G
Sbjct: 678 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 737
Query: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052
P + +T GP+++ K+ EK +DS S +++ P + V
Sbjct: 738 -GTAPVLPGKT--GPTVTQVKA----EKQEDS-----ESSEEESDSEEAAASPAQVKTSV 785
Query: 1053 SSLQLKGQ--SQTSPDHRSDTSSP-----EVRQSHSESPSLQSKSQTSPKGGRSRSSSPV 1105
Q K + +P + S+P Q+ SPS +P+ + P
Sbjct: 786 KKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPA 845
Query: 1106 TELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESK 1165
+ + S + P SG S E+S + ++ + V + Q R A +K
Sbjct: 846 S-VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK 904
Query: 1166 EKMALPPQEDATASPP-----------RQKDKFSPFPVQDRP-------------ESSLV 1201
E P++ A +PP +Q D S D + L+
Sbjct: 905 ES----PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 1202 FKDTLRTP------PRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILS- 1254
F D R+P P + A + + + S +SS + E +V+ PA Q L+
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVI-----PATQCLTP 1015
Query: 1255 HLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEH 1314
+ + + M T++ +P+ A S +S + + E P+ S P P
Sbjct: 1016 GIRTNVVTMPTAHPRIAPKASMAGASS--SKESSRISDGKKQEGPATQVSKKNPASLPLT 1073
Query: 1315 KELSNSPLRENSFGSPLEFRNSGPLGTEMNTG---FSSEVKEDLNGPFLNQLETDPSLDM 1371
+ ++ S P R G + G +S + N+L P L
Sbjct: 1074 QAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLR-KPKLPE 1132
Query: 1372 KEQSTR----SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVP-RTPSRERSSSASSPE 1426
+Q+T+ S S S E+ G + S+ L P RT + ++A S E
Sbjct: 1133 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSE 1192
Query: 1427 MKDGLPRTPSRRSRSG-SSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPE 1485
D + PS+ SG +PGL TP+ S ++P + P S ++ D +
Sbjct: 1193 --DDVV-APSQSLLSGYMTPGL-----TPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1244
Query: 1486 PKALPQ------TPRPRSRSPSSPELNNKCLTPQRERSGSESS--VDQKTVARTPLGQ-- 1535
+A PQ +P+ + +S K P++ ++S Q + + LGQ
Sbjct: 1245 QEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPW 1304
Query: 1536 --RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSP 1593
+ + V QER + + ++ R+R SG P
Sbjct: 1305 PLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQP---------- 1354
Query: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSR-SGSSSKGRGPSPEGS 1652
+ +P K K + + SPE + + +R + SG + +G GS
Sbjct: 1355 ----AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1410
Query: 1653 SSTESSPEHPPKS--RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
+ PE + T G +S+P+ K + + +R+ + E +KA+ + S
Sbjct: 1411 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSE 1470
Query: 1711 SSSPETRSR 1719
S S + + +
Sbjct: 1471 SPSQKKKKK 1479
Score = 115 bits (288), Expect = 6e-25
Identities = 288/1530 (18%), Positives = 550/1530 (35%), Gaps = 199/1530 (13%)
Query: 396 EASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISS 455
+A TR P + E SS E + K + +S+ S A P S +E +
Sbjct: 72 QAKKTRVSDPISTSE-----SSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 456 SPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRR 515
+ T K K+ + P G++ + + + +S P+ S + +
Sbjct: 127 AETEK--------AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE--- 175
Query: 516 SRSAQRWGRSRSPQR--RGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573
S +G + P G++ S S S T G+ S + + + S +T+
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP-SVKPAQVKASSVSTKESP 234
Query: 574 RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRR 633
+ G+ TP + + + P +R + + S + + TRS V+
Sbjct: 235 ARKAAPAPGKVGDVTP-QVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
Query: 634 RS-----RSRSPARRSGRSRSRTPARRGRS---RSRTPARRGRSRSRTPARRSGRSRSRT 685
R+ S + + TPA G++ S+T A + S + + S S T
Sbjct: 294 SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET 353
Query: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS----GSSSERKNKSRTSQRRS 741
PA + +++ S S V + ++ R+G + G + K++ +R
Sbjct: 354 PAAKALLQAKA-----SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE 408
Query: 742 RSNSSPEMKKSR--ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKS-------QT 792
S SS E S ++ S +P+ +A S + G++P P +K+ Q
Sbjct: 409 DSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 468
Query: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852
+ S SS ++ S + +++ P KS S P K PP +
Sbjct: 469 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 528
Query: 853 GSITSPQANEQSVTPQRRSCFESSPDPE----LKSRTPSRHSCSGSSPPRVKSSTPPRQS 908
+P A S E S D + P++ G+ +S+P +
Sbjct: 529 VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 588
Query: 909 PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV-ESRLLPRY 967
P ++ +VKA P S S S + + P + +++ P+
Sbjct: 589 PQKAGPVAVQVKAE-KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
Query: 968 SHSGSSSPDTKVKPETP-PRQ-----SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKS 1021
+++ +S+ V+ T PR+ S +GS SP Q P S S +S +EK+
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGS-SPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQ-LKGQS-----QTSPDHRSDTSSPE 1075
++ S+ VK+++ P + G + L G++ Q + + D+ S E
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 1076 VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQ 1135
E+ + ++ +TS K ++ + A+R+P +G SA + + + Q
Sbjct: 767 EESDSEEAAASPAQVKTSVK----KTQAKANPAAARAP--SAKGTISAPGKVVTAAA--Q 818
Query: 1136 SRFQSDSSSYPTV---DSNSLLGQSRLETAESKEKMALP------PQEDATASPPRQ-KD 1185
++ +S S P V ++++L + + +A P+ED+ +S +
Sbjct: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSE 878
Query: 1186 KFSPFPVQDRPESSLVFKDTLRTPPRE--RSGAGSSPETKEQNSALPTSSQDEELMEVVE 1243
+ + Q +P P +E R GA +P K SA QD+
Sbjct: 879 EEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDD------- 931
Query: 1244 KSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVS---LTLDQSQSQASLEAVEVPS 1300
S E S S+ E+ V + + +D ++S A A +
Sbjct: 932 -------------SGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQA 978
Query: 1301 MASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFL 1360
A+S +P S S R +S S E + P + G + V +
Sbjct: 979 QAAS------TPRKARASESTARSSS--SESEDEDVIPATQCLTPGIRTNV--------V 1022
Query: 1361 NQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSS 1420
P + K +S S D ++ G ++ S +P ++P T + +
Sbjct: 1023 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPA--SLPLTQAALKVL 1080
Query: 1421 SASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSEC 1480
+ + E + + RT S G+ GT +P T
Sbjct: 1081 AQKASEAQPPVARTQP-------SSGVDSAVGT---------------LPAT-------- 1110
Query: 1481 DSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRE---RSGSESSVDQKTVARTPLGQRS 1537
SP+ ++ + R P PE+ P+ S+SS + P G +S
Sbjct: 1111 --SPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1168
Query: 1538 RSGSSQELDVKPSASP---QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594
+ L PS + +E + S D A +++ L G +P S+ +P+
Sbjct: 1169 ----AHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPK 1224
Query: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
SSP V + A+ D E K P A ++G G +P+ S
Sbjct: 1225 LD---SSPSVS----STLAAKDDPDGKQEAK-PQQAAGMLSPKTGGKEAASGTTPQKSRK 1276
Query: 1655 TESSPEHPPKSRTARRGSRSS-----PEPKTKSRTPP-------------RRRSSRSSPE 1696
+ +P S A + + + P P +++ R++ ++ E
Sbjct: 1277 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1336
Query: 1697 LTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756
+RK SR+ + + P R+ PR ++ + + E E S S + + S + K
Sbjct: 1337 SSRKGWESRKRKLSGDQPAART---PRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRD 1393
Query: 1757 SRRGRSPSPKPRGLQRSRSR--SRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRR 1814
G K +G S+ E+ + G + ++++ +S R +
Sbjct: 1394 KASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE 1453
Query: 1815 RGGSGYHSRSPARQESSRTSSRRRRGRSRT 1844
+ ++ + ++S S ++++ + +T
Sbjct: 1454 KKEKKKKAKKASTKDSESPSQKKKKKKKKT 1483
Score = 108 bits (269), Expect = 9e-23
Identities = 246/1329 (18%), Positives = 451/1329 (33%), Gaps = 188/1329 (14%)
Query: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
G+ TPQ +G G+ K + + S E ++ + RS+ KA
Sbjct: 243 GKVGDVTPQVKG--GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV------KAS 294
Query: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
++ R+ S + K TP ++G+ + K+ P S SSS + +TP
Sbjct: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 831 --------------SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
S+ +S+ + G P T P + + SS
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSS 414
Query: 877 PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKA------IISPRQRSH 930
+ + + P++ SG +P +S P ++SP + ++P P K + +Q
Sbjct: 415 EESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED 474
Query: 931 SGSSSPSPSRVTSRTTPRRSRSVSPCSN------VESRLLPRYSHSGSSSPDTKVKPETP 984
S SSS + V P + + P KV P TP
Sbjct: 475 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 534
Query: 985 PRQ-------SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCA 1037
Q S S S + P + + QEKS +++Q+ P S
Sbjct: 535 SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA-------QEKSLGNILQAKPTSSPAKG 587
Query: 1038 GVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQ-SKSQTSPKG 1096
+ + P + S+ S D +P + P+L+ +++ PK
Sbjct: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
Query: 1097 GRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQ 1156
+ +S+ V + + + G + SP +G SP + + P DS+S
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGT-ATSP---AGSSPA----VAGGTQRPAEDSSS---S 696
Query: 1157 SRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGA 1216
++ E K +A+ T + K P + + T P
Sbjct: 697 EESDSEEEKTGLAV------TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLP------ 744
Query: 1217 GSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEE 1276
G + T Q A +D E E SEE A +S K + +N P
Sbjct: 745 GKTGPTVTQVKA--EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN----PAAAR 798
Query: 1277 RPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKE-LSNSPLRENSFGSPLEFRN 1335
P+ T+ + A S P +P++ L+ P S G +
Sbjct: 799 APSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
Query: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPS---------LDMKEQSTR--------- 1377
G E ++G SSE + D + PS L ++S R
Sbjct: 859 QAQTGPEEDSG-SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 917
Query: 1378 -------------SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVP-RTPSRERSSSAS 1423
SG SS E D A ++S Q I P++ P R+P+ ++ A
Sbjct: 918 KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
Query: 1424 SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS 1483
+ S + SS D P+ L +PG++ T
Sbjct: 978 AQAASTPRKARASESTARSSSSESEDEDVIPATQCL---TPGIRTNVVT----------- 1023
Query: 1484 PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ 1543
P A P+ S + +S + ++ +++ G + V +K A PL Q + +Q
Sbjct: 1024 -MPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ 1082
Query: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603
+ + P R++ S DS T +SP+ S + R PE
Sbjct: 1083 K--ASEAQPPVARTQPSSGVDSAVGT--------LPATSPQSTSVQAKGTNKLRKPKLPE 1132
Query: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
V+ +A + DSS S SGS G G P+G+ S + P
Sbjct: 1133 VQQATKAPESSDDSEDSSD-------------SSSGSEEDGEG--PQGAKSAHTLGPTPS 1177
Query: 1664 KSRT--ARRGSRSSPEP------------KTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
++ T + SS + T TP ++S+++P+L +S + +
Sbjct: 1178 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVS-STLA 1236
Query: 1710 ASSSPETRSRTPPRHRR---SPSVSSPEPAE---KSRSSRRRRSASSPRTKTTSRRGRSP 1763
A P+ + P+ SP E A +S + ++ A +P+ T + +
Sbjct: 1237 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1296
Query: 1764 S---PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY 1820
+P L ++ ++ K T T++ R SR +R+ G
Sbjct: 1297 QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESR--KRKLSGDQP 1354
Query: 1821 HSRSPARQESSRTSSRRRRGRS----RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRS 1876
+R+P ++ + + S +T TS+ +++ + K + + S +
Sbjct: 1355 AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK 1414
Query: 1877 RSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR------SRTPPV 1930
+ + S +S+ + +R + + +++++ S +P
Sbjct: 1415 DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1474
Query: 1931 TRRRSRSRT 1939
+++ + +T
Sbjct: 1475 KKKKKKKKT 1483
Score = 107 bits (267), Expect = 2e-22
Identities = 261/1322 (19%), Positives = 483/1322 (36%), Gaps = 160/1322 (12%)
Query: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKK----DRGRRSESSSP---RRERKKS 212
A++ AP P K + + P K+ KK +++ + G SE +P R + K S
Sbjct: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
Query: 213 SKKKKHRSESESKKR---KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
K + R+ S K K +P P K + S T A K S+S +S+
Sbjct: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAV-------ASQTKAGKPEEDSESSSEESS 347
Query: 270 SSSD-TSRSRSRSAAAKTHTTALAGRSPSPA--SGRRGEGDAP---------FSEPGTTS 317
S + T +++ A + T+ G + +PA S R+G AP ++ G
Sbjct: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
Query: 318 TQRPSSPETATKQPSSPYEDKDKDK--KEKSATRPSPSPERSSTGPEPPAPT-PLLAERH 374
SS E + + +P + K K + ++A+ P+ R P PP T P A+
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPP--KSPEKLPQSSS-----SESSPPSPQP 427
G + + + + + + A+ + P KSP+ P S+ + + P P P
Sbjct: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP-P 526
Query: 428 TKVSRHASSSPESPKPAPAPGSHREISSS-----PT----SKNRSHGRAKRDKSHSHTPS 478
KV S+ + S E S S PT ++ +S G + K S +P+
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-SPA 585
Query: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
+ + P + ++ P S S S A + Q + + PQ
Sbjct: 586 KGPPQKAGPVAV---QVKAEKPMDNSESSEESSDSADSEEAP--AAMTAAQAKPALKIPQ 640
Query: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
+ NT + R G R T +PA G ++ PA S S
Sbjct: 641 TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG--GTQRPAEDSSSSEE 698
Query: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR-RRSRSRSPARRSGRSRSRTPARRGR 657
++ G+++S + PV+ + +P P + G
Sbjct: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV---------LPGKTGP 749
Query: 658 SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
+ ++ A + + + +PA+ S +T + + +R
Sbjct: 750 TVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA----------ARA 799
Query: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
P +G + + + +++RS S P ++ + S+ +R +S S
Sbjct: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS---------- 849
Query: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
G + ++QT P SGSS+ ++ S + + + P K+ +
Sbjct: 850 --VGKAVATAAQAQTGPEED-SGSSEEESDSE---EEAETLAQVKPSGKTHQIRAALAPA 903
Query: 838 SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897
K + TPP + ++ QA +Q S ES D E + S PP
Sbjct: 904 KESPRKGAAPTPPGKTGPSAAQAGKQD--DSGSSSEESDSDGEAPAAVTSAQVI---KPP 958
Query: 898 RVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSR---------VTSRTTPR 948
+ P +SP+ ++ + +A +PR+ S S++ S S T TP
Sbjct: 959 LI--FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 1016
Query: 949 RSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPS 1008
+V R+ P+ S +G+SS + +Q P +V + P
Sbjct: 1017 IRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE-----GPATQVSKKNPASLP 1071
Query: 1009 LSGSKSPCPQEKSKDS---LVQSCPGS-LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS 1064
L+ + +K+ ++ + ++ P S + G +T P +S+Q KG ++
Sbjct: 1072 LTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQS-----TSVQAKGTNKLR 1126
Query: 1065 ----PDHRSDTSSPEVRQSHSESPSLQSKSQ---TSPKGGRSRSSSPVTELASRSPIRQD 1117
P+ + T +PE +S S S+ P+G +S + T + + + +
Sbjct: 1127 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEET 1186
Query: 1118 RGEFS-------ASPMLKSGMSPEQSRFQSDSS-SYPTVDSNSLLGQSRLETAESKEKMA 1169
E S + +L M+P + S +S + P +DS+ + + + K
Sbjct: 1187 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1246
Query: 1170 LPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSAL 1229
PQ+ A P+ K + P+ S R P + +S + N
Sbjct: 1247 AKPQQAAGMLSPKTGGKEAASGT--TPQKS-------RKPKKGAGNPQASTLALQSNITQ 1297
Query: 1230 PTSSQDEELMEVVEKSEEPAGQILSH-LSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ 1288
Q L E + + ++L+ L E K++ + ESS + E L+ DQ
Sbjct: 1298 CLLGQPWPLNEA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPA 1355
Query: 1289 SQASLEAVEVPSMASSWGGPHFSPEHKELSN--SPLRENSFGSPLEFRNSGPLGTEMNTG 1346
++ + A G SPE ++ R+ + G E + G LG++ G
Sbjct: 1356 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---G 1412
Query: 1347 FSSEVKEDLN---GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSIS 1403
E +E+L G +++P K++ +S + + +KA +S +
Sbjct: 1413 AKDEPEEELQKGMGTVEGGDQSNPK--SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSE 1470
Query: 1404 SP 1405
SP
Sbjct: 1471 SP 1472
Score = 104 bits (259), Expect = 1e-21
Identities = 286/1492 (19%), Positives = 542/1492 (36%), Gaps = 149/1492 (9%)
Query: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR--SESESKKRKHRSPTPKSKRKSKDKK 244
Q KK + D SESS E + + K R S + S + K K K++ +K
Sbjct: 72 QAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
Query: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
++ ++ P P + + ++ + +S +SA +TT + S
Sbjct: 132 AGKTGNSMPHP--------ATGKTVANLLSGKSPRKSAEPSANTTLV--------SETEE 175
Query: 305 EGDAP----FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
EG P ++PG S + S T S + D + K + +P+ S +
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSD-----ETDVEGKPSVKPAQVKASSVST 230
Query: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
E PA A G TP + PP++ R + P + E + S SE
Sbjct: 231 KESPARKAAPAPGKVGD-----VTPQVKGGALPPAK----RAKKPEEESESSEEGSESEE 281
Query: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGS-HREISSSPTSKN---RSHGRAKRDKSHSHT 476
P+ ++V APA G+ + + +P K S +A + + S +
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRR----- 531
S S A + +++ K + S ++ + R G + +P +
Sbjct: 342 SSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP---AKESPRKGAAPAPPGKTGPAV 398
Query: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR 591
++++ +R S+S + + + + + ++P R S PA+ + PA
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS---APAKESPRKGAAPAP 455
Query: 592 RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT 651
R + + + R S R + + + +SP + +
Sbjct: 456 PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG 515
Query: 652 PARRGRSRSRTPARRGRSRSRTPARRSGR----SRSRTPARRGRSRSRTPRR---GRSRS 704
P +G P G+ TP+ + G+ S S + S P + +S
Sbjct: 516 PLGKGAG----PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS 571
Query: 705 RSLVRRGRSHSR----TPQRRGRSG---SSSERKNKSRTSQRRSRSNSSPEMKKSRISSR 757
+ + + S PQ+ G + + + S +S+ S S S E + +++
Sbjct: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 631
Query: 758 RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR-----SRSGSSQPKAKSRTPP 812
+L P++KA + + + + + P + PR+ S +GSS A P
Sbjct: 632 AKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 689
Query: 813 RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK---VKSGTPPRQGSI---TSPQANEQSVT 866
SSS ++ KT + + K VK+ + P +GS+ T+P ++
Sbjct: 690 AEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP 749
Query: 867 PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS---TPPRQSPSRSSSPQPK----- 918
+ E D E S S + +SP +VK+S T + +P+ + +P K
Sbjct: 750 TVTQVKAEKQEDSE-SSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 808
Query: 919 ----VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV-----SPCSNVESRLLPRYSH 969
V A +QRS S P + S R SV + + +++ P
Sbjct: 809 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE-ED 867
Query: 970 SGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSC 1029
SGSS ++ + E S + A P S +P P K+ S Q+
Sbjct: 868 SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 927
Query: 1030 PGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSK 1089
S + +S + GE+ V+S Q+ D + P + +++ S K
Sbjct: 928 KQDDSGSSSEESDS-DGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
Query: 1090 SQTSPKGGRSRSSSPVTE---LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYP 1146
++ S RS SS E A++ R P ++P+ S + SS
Sbjct: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 1046
Query: 1147 TVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTL 1206
+ S+ + K +LP + A ++ + P + +P S +
Sbjct: 1047 SRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGV------ 1100
Query: 1207 RTPPRERSGAGSSPETKEQNSALPTSSQDE----ELMEVVEKSEEPAGQILSHLSSELKE 1262
S G+ P T Q++++ ++ +L EV + ++ P S SS+
Sbjct: 1101 ------DSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS 1154
Query: 1263 MSTSNFE------SSPEVEERPAVSLTL-DQSQSQASLEAVEVP--SMASSWGGPHFSPE 1313
S + E S+ + P+ + TL +++ +++S + V P S+ S + P +P
Sbjct: 1155 GSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1214
Query: 1314 HKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKE 1373
+ + S + + +S S S L + + E K L+ P KE
Sbjct: 1215 NSQASKATPKLDSSPSV-----SSTLAAKDDPDGKQEAKPQQAAGMLS-----PKTGGKE 1264
Query: 1374 QSTRSSGHSSSELSPDAVE-KAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLP 1432
++ ++ S + A +A + QS + L P P E AS ++ L
Sbjct: 1265 AASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP-WPLNEAQVQASVVKVLTELL 1323
Query: 1433 RTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT 1492
++ + R G + R LSG P RTP + + + E +
Sbjct: 1324 EQERKKVVDTTKESSRKGWESRKR-KLSGDQPA----ARTPRSKKKKKLGAGEGGEASVS 1378
Query: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS 1552
P S + +K +E+ G S Q + G+ + D S
Sbjct: 1379 PEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKS 1438
Query: 1553 PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604
+E+ +SD K K + +++++ S+ + +S S+ ++ + + V
Sbjct: 1439 KKEKKKSDKR--KKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
Score = 103 bits (258), Expect = 2e-21
Identities = 285/1492 (19%), Positives = 511/1492 (34%), Gaps = 206/1492 (13%)
Query: 1343 MNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS--ELSPDAVEKAGMSSNQ 1400
++T SSE +E+ + P L S + SS E + EKAG + N
Sbjct: 82 ISTSESSEEEEEAEA---ETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGN- 137
Query: 1401 SISSPVLDAVP------RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
S+ P ++P + SA++ + + + + PG+
Sbjct: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
Query: 1455 SRHSLSGSSPGMKDIPRTPS----RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCL 1510
S + SS D+ PS + ++ S+ E A P P +P++ L
Sbjct: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGAL 257
Query: 1511 TPQR-----ERSGSESSVDQKTVARTPLGQRSRSGSSQE-LDVKPSASPQERSESDSSPD 1564
P + E S ++ P G RS+ +S++ L V+ +++P + + +
Sbjct: 258 PPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
Query: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
+ + ++++G PE DS+S S S E +A +A++ +S
Sbjct: 318 APPGKAGAVASQTKAGK-PEEDSESS----SEESSDSEEETPAAKALLQAKASGKTSQVG 372
Query: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR------SSPEP 1678
A AP S KG P+P G + P A+ G R SS E
Sbjct: 373 AASAPA-------KESPRKGAAPAPPGKTG--------PAVAKAQAGKREEDSQSSSEES 417
Query: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR-------HRRSPSVS 1731
++ P + + S +P++ + ++ S ++P +T P + S S
Sbjct: 418 DSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS 477
Query: 1732 SPEPAEKSRSSRRRRSAS-------SPRTKTTSRRGRSP-----SPKPRGLQRSRSRSRR 1779
S E ++ R + +A+ SP+ K S G P P P G + S +
Sbjct: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 1780 -------EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR 1832
++ + D S T+ + +S + + + + SPA+ +
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKP------TSSPAKGPPQK 591
Query: 1833 TSSRRRRGRSRTPPTSRKRSRSRTSPA-----PWKRSRSRASPATHRRSRSRTPLISRRR 1887
+ ++ P + + S + A P + ++A PA P +
Sbjct: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT 651
Query: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947
+ ++ +PV R T R+ + + S T S S +
Sbjct: 652 ASAKVAPV-----RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 1948 SRTPPVTRRRS-------RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
V + +S ++ + PV + + + + T ++ S +S
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 2001 VTRRRSRSRTSPVTRRRSRSRT-----PPAIRRRSRSRTPLLPRK------RSRSRSPLA 2049
+ SP + S +T P A R S T P K +++ RSP
Sbjct: 767 EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSK 826
Query: 2050 IRRRSRSRTPRT--ARGKRSLTRSPPAIRRRSA--------SGSSSDRSRSATPPAT--R 2097
++ R+ T ARG S+ A+ + SGSS + S S T +
Sbjct: 827 VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Query: 2098 NHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMM 2157
+T + + R +PTP PG P + QAG
Sbjct: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTP------PGKTGPSAA---------QAGKQ-- 929
Query: 2158 DGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP-----PSMSAAGLAARMSQVP 2212
D +S E+ + A+T+ + +PP P+ S AG AA +Q
Sbjct: 930 --------DDSGSSSEESDSDGEAPAAVTSAQV--IKPPLIFVDPNRSPAGPAATPAQAQ 979
Query: 2213 APVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLAS 2272
A R + + +S + + TP I T V + P A ++A
Sbjct: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
Query: 2273 PRTAVAPSAVNLADPRTPTAPAVNLAGAR------TPAALAALSLTGSGTPPTAANYPSS 2326
++ S ++ D + PA ++ T AAL L+ S P A S
Sbjct: 1040 ASSSKESSRIS--DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1097
Query: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
S A + P+S A G+ + A AP S + S
Sbjct: 1098 SGVDSAVGTLPATSPQSTSVQAK----GTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS 1153
Query: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQ 2446
+ E G P ++ P+ + E A S APSQSLL
Sbjct: 1154 SGSEEDGEG----PQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTP 1209
Query: 2447 PRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDV 2506
+P S S + TP S S +V++T ++ D +G P
Sbjct: 1210 GLTPANSQAS--------KATPKLDS----SPSVSSTLAAKDDPDGKQEAK----PQQAA 1253
Query: 2507 GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS---SSSDS 2563
G TG ++ A + P K R+ + + +S+ + S+ + + +
Sbjct: 1254 GMLSPKTGGKE--AASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQV 1311
Query: 2564 EGSSLPVQPEVALKRVPSPTPAPKEAVREG-----------RPPEPTP--AKRKRRSSSS 2610
+ S + V E+ + KE+ R+G +P TP K+K+ +
Sbjct: 1312 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1371
Query: 2611 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP-QALPKPASPKKPP 2669
+S S +S++S + +S S AK P + L K +
Sbjct: 1372 GGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVE-- 1429
Query: 2670 PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
G +S K D R E+++ + + S +D +S S ++ ++
Sbjct: 1430 -GGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKK 1480
Score = 102 bits (253), Expect = 7e-21
Identities = 276/1514 (18%), Positives = 523/1514 (34%), Gaps = 204/1514 (13%)
Query: 1212 ERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES- 1270
E A ++P NS++ + + E + E AG+ + + + +N S
Sbjct: 95 EAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSG 154
Query: 1271 -SPEVEERPAVSLTL----DQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLREN 1325
SP P+ + TL ++ S + A P M S+ S + S+ E
Sbjct: 155 KSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEG 214
Query: 1326 S--------FGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTR 1377
S + + S G +V + G L + + + +S+
Sbjct: 215 KPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSE 274
Query: 1378 SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSR 1437
G S E +P AG S S +L R S+ A K P P +
Sbjct: 275 E-GSESEEEAP-----AGTRSQVKASEKILQV------RAASAPAKGTPGKGATPAPPGK 322
Query: 1438 RSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS-RGRSECDSSPEPKALPQTPRPR 1496
S + +G P S S S TP+ + + +S + + P
Sbjct: 323 AGAVAS----QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPA 378
Query: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQKT---VARTPLGQRSRSG--SSQELDVKPSA 1551
SP R G+ + KT VA+ G+R SS+E D + A
Sbjct: 379 KESP---------------RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 423
Query: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS-------RLSPRRSRSGSSPEV 1604
P + S +P +A + P ++ R G++P K+ ++ + S SS E
Sbjct: 424 -PAQAKPSGKAPQVRAAS-APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE 481
Query: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG------------- 1651
D R A A + + P K+P + G KG GP P G
Sbjct: 482 SDSDREALAAMNAAQVKPLGKSPQVKPASTMGM-GPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 1652 ------SSSTESSPEHPPKSRTA-------RRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698
SSS ESS + TA G+ +P + P +++ + ++
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR--RRSASSPRTKTT 1756
+ + S SS S P + + + +PA K ++ +++ ++ K
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPA---AMTAAQAKPALKIPQTKACPKKTNTTASAKVA 657
Query: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRR-RDRSGSSQSTSRRRQRSRSRSRVTRRRR 1815
R + +P+ G S + S T+R + S SS+ + +++ V + +
Sbjct: 658 PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKS 717
Query: 1816 GGSGYHSRS---PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPAT 1872
G G ++ P + + ++ G++ T K + S + + S S + A+
Sbjct: 718 VGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAAS 777
Query: 1873 HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
+ ++ S ++++++ +P + R ++ +++ A+ +++RS S+ P R
Sbjct: 778 PAQVKT-----SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVR 832
Query: 1933 RRSRSRTPTTRRRSRSRTPPVTRR---RSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPV 1989
S T R + P V + ++++T P S S S +
Sbjct: 833 NPQNS---TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD-----SEEEAETL 884
Query: 1990 TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLA 2049
+ + +T + + ++ SP R+ + TPP S ++ S S
Sbjct: 885 AQVKPSGKTHQIRAALAPAKESP---RKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES-- 939
Query: 2050 IRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2109
S P + + PP I + S +ATP + S R +
Sbjct: 940 ---DSDGEAPAAVTSAQVI--KPPLI---FVDPNRSPAGPAATPAQAQAASTPRKARASE 991
Query: 2110 NSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQR 2169
+++R S P +C +PG+ R
Sbjct: 992 STARSSSSESEDEDVIPATQCLTPGI---------------------------------R 1018
Query: 2170 TSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLA 2229
T+V +++ TA P + A+ A S+ + + + PA ++
Sbjct: 1019 TNV---------------VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVS 1063
Query: 2230 SRIPAA----SAAAMNLASARTPAIP-TAVNLADSRTPAAAAAMNLASPR-TAVAPSAVN 2283
+ PA+ AA LA + A P A S +A + SP+ T+V N
Sbjct: 1064 KKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTN 1123
Query: 2284 LADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRS 2343
R P P V A + P + S + +++ PQ SA+ +GP
Sbjct: 1124 KL--RKPKLPEVQQA-TKAPES----SDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTP 1176
Query: 2344 AHATAPVNIAGSRTAA--ALAPA-SLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPP 2400
+ V + ++ +AP+ SL S M P L+ AN + + S ++
Sbjct: 1177 SRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLA 1236
Query: 2401 LLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP-AQDQPRSPVPSAFSDQS 2459
D + + M S + + G P +S P P++ + S+ +
Sbjct: 1237 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1296
Query: 2460 RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPS 2519
+CL+ Q P+ +Q +S T + ++ +G QP+
Sbjct: 1297 QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG-DQPA 1355
Query: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD-----------SEGSSL 2568
A K++ + +S S +S++S + +S D S+G+
Sbjct: 1356 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK- 1414
Query: 2569 PVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628
+PE L++ ++ + + + KRK+ + +S+ S S S
Sbjct: 1415 -DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1473
Query: 2629 SSSSSSSSSSSSSS 2642
++ +
Sbjct: 1474 QKKKKKKKKTAEQT 1487
Score = 97.4 bits (241), Expect = 2e-19
Identities = 238/1250 (19%), Positives = 431/1250 (34%), Gaps = 179/1250 (14%)
Query: 892 SGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS------RVTSRT 945
+ + PR+ S+ SS + K KA + +G+S P P+ + S
Sbjct: 98 TAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMPHPATGKTVANLLSGK 155
Query: 946 TPRRSRSVSPCSNVESRL-----LPRY--------------------SHSGSSSPDTKVK 980
+PR+S S + + S +P + + S S D + K
Sbjct: 156 SPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGK 215
Query: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSP--------------CPQEKSKDSLV 1026
P P Q + S+S + P P G +P P+E+S+ S
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS-E 274
Query: 1027 QSCPGSLSLCAGVKSSTPPGESYFGV--SSLQLKG-----------------QSQT---S 1064
+ AG +S E V +S KG SQT
Sbjct: 275 EGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGK 334
Query: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
P+ S++SS E S E+P+ ++ Q +++S +++ + S ++ A+
Sbjct: 335 PEEDSESSSEESSDSEEETPAAKALLQ-------AKASGKTSQVGAASAPAKESPRKGAA 387
Query: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK 1184
P P ++ Q+ + QS E ++S+E+ P Q + P+ +
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDS--------QSSSEESDSEEE--APAQAKPSGKAPQVR 437
Query: 1185 DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ----NSALPTSSQDEELME 1240
+P R K PPR+ A + + +Q S+ S D E +
Sbjct: 438 AASAPAKESPR-------KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
Query: 1241 VVEKSE-EPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299
+ ++ +P G+ S ++K ST + P + + A + E
Sbjct: 491 AMNAAQVKPLGK-----SPQVKPASTMGMGPLGK-GAGPVPPGKVGPATPSAQVGKWEED 544
Query: 1300 SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
S +SS S + +P +E S G+ L+ + T ++ GP
Sbjct: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK---------PTSSPAKGPPQKAGPV 595
Query: 1360 LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS 1419
Q++ + +D E S SS + SE +P A+ A + ++ P A P+ + S
Sbjct: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA--QAKPALKIPQTKACPKKTNTTAS 653
Query: 1420 SSASSPEMKDGLPR-TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD--------IP 1470
+ + + PR + S +GSSP + G+ P+ S S ++ +
Sbjct: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
Query: 1471 RTPSRGRS---ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527
+ S G+ + S P +L Q P + P + Q + SE D +
Sbjct: 714 QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEE 773
Query: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
A +P ++ +Q +A + S+P +QRS S P V +
Sbjct: 774 AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN 833
Query: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSG-----------SDSSPEPKAPA---PRALP 1633
+ S P V A +AQ+G SDS E + A P
Sbjct: 834 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKT 893
Query: 1634 RRSRSG------SSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR 1687
+ R+ S KG P+P G ++ P + GS SS E + P
Sbjct: 894 HQIRAALAPAKESPRKGAAPTPPG----KTGPSAAQAGKQDDSGS-SSEESDSDGEAPAA 948
Query: 1688 RRSSR--SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV---SSPEPAEKSRSS 1742
S++ P + S +A+ + + TP + R S S SS E ++
Sbjct: 949 VTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIP 1008
Query: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ 1802
+ RT + P P+ S S +E +R + + + G + S++
Sbjct: 1009 ATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS-SSKESSRISDGKKQEGPATQVSKKNP 1067
Query: 1803 RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWK 1862
S ++ + ++ P +RT P+S S T PA
Sbjct: 1068 ASLPLTQAALKVLAQKASEAQPPV---------------ARTQPSSGVDSAVGTLPATSP 1112
Query: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR 1922
+S S + T++ + + P + ++ +P S S + + P +
Sbjct: 1113 QSTSVQAKGTNKLRKPKLPEV----QQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1168
Query: 1923 SRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRS 1982
+ + P +R + P S TP +T S++ + S
Sbjct: 1169 AHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSS 1228
Query: 1983 RSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT-RRRSRSRTPPAIRRRSR 2031
S +S + + +++ SP T + + S T P R+ +
Sbjct: 1229 PSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1278
Score = 94.0 bits (232), Expect = 2e-18
Identities = 260/1333 (19%), Positives = 466/1333 (34%), Gaps = 207/1333 (15%)
Query: 1482 SSPEPKALPQTPR--PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR- 1538
S E +A +T + PR S +S L + +E++ +E+ KT P +
Sbjct: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
Query: 1539 -----SGSSQELDVKPSASP---QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
SG S +PSA+ E E S P A + + ++ SS E S S
Sbjct: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSS- 206
Query: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
+V+ KP P AQ + S ++PA +A P + G + P +
Sbjct: 207 --------SDETDVEGKPSVKP-AQVKASSVSTKESPARKAAPAPGKVGDVT----PQVK 253
Query: 1651 GSSSTESSPEHPPK--SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSR 1708
G + + P+ S ++ GS S E +RS + + K R +
Sbjct: 254 GGALPPAKRAKKPEEESESSEEGSESEEEAPA---------GTRSQVKASEKILQVRAAS 304
Query: 1709 SASSSPETRSRTPPRHRRSPSVSSP----EPAEKSRSSRRRRSASSPRTKTTSRRGRSPS 1764
+ + + TP ++ +V+S +P E S SS S S T
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET----------- 353
Query: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
P + L ++++ + + G++ + ++ R + + + G + +++
Sbjct: 354 PAAKALLQAKASGKTSQV---------GAASAPAKESPR-KGAAPAPPGKTGPAVAKAQA 403
Query: 1825 PARQESSRTSSRRRRGRSRTPPTSR---KRSRSRTSPAPWKRS-RSRASPATHRRSRSRT 1880
R+E S++SS P ++ K + R + AP K S R A+PA R++
Sbjct: 404 GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
Query: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
+ + + RS S S + R + + A ++ + ++P V + P
Sbjct: 464 AQVQVGKQEEDS------RSSSEESDSDREALA-AMNAAQVKPLGKSPQVKPASTMGMGP 516
Query: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
+ PV + TP + + + S S V + ++
Sbjct: 517 LGKGAG-----PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS 571
Query: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPR 2060
+ TS + + P A++ ++ P S S S S
Sbjct: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK-----PMDNSESSE-----ESSDSADSE 621
Query: 2061 TARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRP 2120
A + ++ PA++ A P T + ++ PV + +
Sbjct: 622 EAPAAMTAAQAKPALKIPQTK---------ACPKKTNTTASAKVAPVRVGTQ-------- 664
Query: 2121 SMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS- 2179
+P SP AG S G + P +S E+ ++
Sbjct: 665 --APRKAGTATSP------------------AGSSPAVAGGTQRPAEDSSSSEESDSEEE 704
Query: 2180 RIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANL--ASRIPAASA 2237
+ LA+T + + AA + + S P++ +T P A + + +
Sbjct: 705 KTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSES 764
Query: 2238 AAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNL 2297
+ S A P V + +T A A +P A APSA T +AP
Sbjct: 765 SEEESDSEEAAASPAQVKTSVKKTQAKA------NPAAARAPSAKG-----TISAP---- 809
Query: 2298 AGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA----TAPVNIA 2353
G AA A + S P N +S+ + PAS VG A A T P +
Sbjct: 810 -GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 2354 GSRTAAALAPASL-TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS 2412
GS + + T A++ P+ + + P R +PP +T PS
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP------GKTGPS 922
Query: 2413 APSQSRMTSERAPSPSSRM-GQAPS-----QSLLPPA--QDQPRSPV-PSAFSDQSRCLI 2463
A + + S S G+AP+ Q + PP D RSP P+A Q++
Sbjct: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ--- 979
Query: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
A +TP S S+ +++ S D PG+ + V P A +++A
Sbjct: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
Query: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSS--------SSSGSSSSDSEGSSLPVQP--- 2572
+KE S ++ S + +S +S+++ QP
Sbjct: 1040 ASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSG 1099
Query: 2573 -EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631
+ A+ +P+ +P +G P K ++ + SS S SS SSS S
Sbjct: 1100 VDSAVGTLPATSPQSTSVQAKGTNKLRKP---KLPEVQQATKAPESSDDSEDSSDSSSGS 1156
Query: 2632 SSSSSSSSSSSSSSSSSPSPAK-------------------PGPQALPKPASPKKPPPGE 2672
+ S+ + P+P++ P L +P P
Sbjct: 1157 EEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1216
Query: 2673 RRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSS---SSERGSRRGQRGDSRS 2729
+ S++ K L S S+S + + P + + QQ++ S + G + G +
Sbjct: 1217 QASKATPK----LDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQ 1272
Query: 2730 PSHKRRRETPSPR 2742
S K ++ +P+
Sbjct: 1273 KSRKPKKGAGNPQ 1285
Score = 78.2 bits (191), Expect = 1e-13
Identities = 189/1033 (18%), Positives = 336/1033 (32%), Gaps = 77/1033 (7%)
Query: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ 1828
G +R + + TR D +S+S+ + ++ T R S + +
Sbjct: 60 GRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLA------STNSSVL 113
Query: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR---SRTPLISR 1885
+ SS + + ++ T K S PA K + S + R+S + T L+S
Sbjct: 114 GADLPSSMKEKAKAETEKAG-KTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172
Query: 1886 RRSRSRTSPVSRRRSRSRTSVTRRRSRSR-ASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944
S + S S S S P V + ++ + +T+
Sbjct: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKE 232
Query: 1945 RSRSRTPP-------VTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSR 1997
+ P VT + PP R + S + S S RS+ +
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292
Query: 1998 TSP-VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPL-LPRKRSRSRSPLAIRRRSR 2055
S + + R+ S + T + + PP S+T P + S S S + S
Sbjct: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES--SDSE 350
Query: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
TP A+ S + +AS + + R PA +G P VA +
Sbjct: 351 EETP-AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG---PAVAKAQAGKR 406
Query: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP---------- 2165
S S +P +P G + + A S G P P
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
Query: 2166 ------DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR--MSQVPAPVPL 2217
+ R+S E+ + A+ A + P + A + + PVP
Sbjct: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 2218 MSLRTA-PAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTA 2276
+ A P+A + + +++ + + +PTAV A ++ + A P ++
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS---LGNILQAKPTSS 583
Query: 2277 VAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPP--TAANYPSSSRTPQAPA 2334
A A P A + ++ S P TAA + + PQ A
Sbjct: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 2335 SANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVS 2394
++ APV + A A + + A +PA++G S+ E S
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQ--APRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDS 701
Query: 2395 GRTSPPL---------LDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445
L + + S P + + AP + G +Q +D
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
Query: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505
S S + + T V +Q+ ++ A A S+ G + V
Sbjct: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
Query: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
+ P L S + ++++ + + S SS S S+ E
Sbjct: 822 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
Query: 2566 SSLP-VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
+L V+P ++ + KE+ R+G PTP + S++ + S SSS S
Sbjct: 882 ETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDS 2684
S + ++ +S+ P+ + GP A P A P R S S + S
Sbjct: 940 DSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSS 999
Query: 2685 LRDSRSL-------------SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
+ + + + P P +SSS+ SR P+
Sbjct: 1000 ESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPA 1059
Query: 2732 HKRRRETPSPRPM 2744
+ ++ P+ P+
Sbjct: 1060 TQVSKKNPASLPL 1072
Score = 71.6 bits (174), Expect = 1e-11
Identities = 121/513 (23%), Positives = 191/513 (37%), Gaps = 66/513 (12%)
Query: 2214 PVPLMSLRT--APAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271
PV L+ + T + L + A AA+ R + P + + + A A A
Sbjct: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRV-SDPISTSESSEEEEEAEAETAKA 101
Query: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSS---R 2328
+PR A S+V AD P++ A S+ T T AN S +
Sbjct: 102 TPRLASTNSSVLGAD--LPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRK 159
Query: 2329 TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLS 2388
+ + A+ LV + P A A + SA A + S +S S
Sbjct: 160 SAEPSANTTLVSETEEEGSVPA-------FGAAAKPGMVSAGQADSSSEDTSSS-----S 207
Query: 2389 AYERVSGRTS-PPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ---SLLPPAQ 2444
V G+ S P +A S + +P++ + AP+P ++G Q LPPA+
Sbjct: 208 DETDVEGKPSVKPAQVKASSVSTKESPAR-----KAAPAPG-KVGDVTPQVKGGALPPAK 261
Query: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
R+ P S+ S GS+S A A T S +L V A P
Sbjct: 262 ---RAKKPEEESESSE---------EGSES-EEEAPAGTRSQVKASEKILQVRAASAPAK 308
Query: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
G P P A+ + S SSS SS S + ++ + + S
Sbjct: 309 --GTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 366
Query: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
+S +V + + KE+ R+G P P P K + + + S SSS
Sbjct: 367 KTS----------QVGAASAPAKESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSE 415
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG---------ERRS 2675
S S + + + S + ++ +PAK P+ PA P+K P E S
Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
Query: 2676 RSPRKPIDSLRDS-RSLSYSPVERRRPSPQPSP 2707
RS + DS R++ +++ + V+ SPQ P
Sbjct: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Score = 70.1 bits (170), Expect = 3e-11
Identities = 104/464 (22%), Positives = 164/464 (35%), Gaps = 44/464 (9%)
Query: 2264 AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
AA + S + V L D T L R AAL + +
Sbjct: 26 AAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTS 85
Query: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
SS +A A PR A + V A P+S+ A A T
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSV-------LGADLPSSMKEKAKAET-EKAGKTGN 137
Query: 2384 RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS-SRMGQAPSQSLLPP 2442
+P A +G+T LL R + + + SE S G A ++
Sbjct: 138 SMPHPA----TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSA 193
Query: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Q S S+ SD+ T V G S+ V ++ S + + PAPG
Sbjct: 194 GQADSSSEDTSSSSDE--------TDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG-- 243
Query: 2503 HSDVGE-PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
VG+ P G P A A +P +E S SS S S + + + S +
Sbjct: 244 --KVGDVTPQVKGGALPPAKRAKKPEEE---SESSEEGSESEEEAPAGTRSQVKASEKIL 298
Query: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621
+S P + P+P P AV A + + S SSS SS
Sbjct: 299 QVRAASAPAKGTPGKGATPAP-PGKAGAV----------ASQTKAGKPEEDSESSSEESS 347
Query: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
S + ++ + + +S +S ++ +PAK P+ PA P K P ++++ ++
Sbjct: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
Query: 2682 ID---SLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG 2722
D S +S S +P + + P R S+ ++ R+G
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVR-AASAPAKESPRKG 450
Score = 42.4 bits (98), Expect = 0.006
Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 7/144 (4%)
Query: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV-DGSSFDPQRRAREAKQPAPE 166
K + G +PA KK ++L A G S + +S + +A+ K
Sbjct: 1346 KRKLSGDQPAARTPRS------KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV 1399
Query: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
K S ++ ++ +K G + ++E+KKS K+KK + + E KK
Sbjct: 1400 KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1459
Query: 227 RKHRSPTPKSKRKSKDKKRKRSRS 250
+ ++ T S+ S+ KK+K+ ++
Sbjct: 1460 KAKKASTKDSESPSQKKKKKKKKT 1483
Score = 39.7 bits (91), Expect = 0.041
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 29/131 (22%)
Query: 184 TPKQKKKKK-------------------KKDRGRRSESSSPRRERK----KSSKKKKHRS 220
TP+ KKKKK K + +R ++S +E+K S+ K
Sbjct: 1358 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1417
Query: 221 ESESKK-----RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTS 275
E E +K PKSK K K K KR + K ++A ++++ DS S S
Sbjct: 1418 EEELQKGMGTVEGGDQSNPKSK-KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKK 1476
Query: 276 RSRSRSAAAKT 286
+ + + A +T
Sbjct: 1477 KKKKKKTAEQT 1487
Score = 34.3 bits (77), Expect = 1.7
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 13/83 (15%)
Query: 162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR-S 220
+P E K V S + K+KKK K+ + + ++E+KK +KK + S
Sbjct: 1416 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE------KKEKKKKAKKASTKDS 1469
Query: 221 ESESKKRKHRSPTPKSKRKSKDK 243
ES S+K+K K K+K+ ++
Sbjct: 1470 ESPSQKKK------KKKKKTAEQ 1486
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 121 bits (304), Expect = 8e-27
Identities = 134/434 (30%), Positives = 180/434 (41%), Gaps = 49/434 (11%)
Query: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM-APALSGANLTS 2382
P S ++P P P++ AP + + A PA A + APA S A
Sbjct: 2370 PGSKKSPPEPVDKRAKAPKAR--PAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPL 2427
Query: 2383 PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP 2442
+P + + R + + R A ++ E SP S+ + P
Sbjct: 2428 ITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDP 2487
Query: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
+ P +S + P AGS S ++ GD + P PG+
Sbjct: 2488 GAGGWQEP-------KSLLSLGSYPPAAGS---SEPKAPWPKATDGD---LAQEPGPGLT 2534
Query: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
D G P + AQ A Q E SSSSSSS SSSSSSSSSSS S + G D
Sbjct: 2535 FEDSGNPKSPDKAQ------AEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGD 2588
Query: 2563 SEGS----SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSS 2618
G + A R SP + + + SSSSSSSSSSSS
Sbjct: 2589 KNGDGGCGTGGRNCSAASSRAASPASSSSSS-----------SSSSSSSSSSSSSSSSSS 2637
Query: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP---GERRS 2675
SSSSSSSSSSSSSSSSSSSSSSSSSSSSSS S + + P P ++
Sbjct: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697
Query: 2676 RSPRKPIDSLRDSRSLSYSPVER------RRPSPQPSPRDQQSSSSERGSRRGQRGDSRS 2729
P K +R ++SP ++ + P PQP+ Q + + SR +R
Sbjct: 2698 ALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHL 2757
Query: 2730 PSHK---RRRETPS 2740
P+ K +R+ PS
Sbjct: 2758 PTTKELAKRQRLPS 2771
Score = 82.0 bits (201), Expect = 7e-15
Identities = 107/427 (25%), Positives = 160/427 (37%), Gaps = 86/427 (20%)
Query: 2358 AAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS 2417
AA L + T + L+ ++P S E V R P +AR P +P+
Sbjct: 2345 AATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAP---KARPAPPQPSPAPP 2401
Query: 2418 RMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSS 2477
TS AP P + + AP+ SL P P +P+ + A+ + G +
Sbjct: 2402 AFTSCPAPEPFAEL-PAPATSLAPA----PLITMPATRPKPKKARAAEESGAKGPRRPGE 2456
Query: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDV-GEPPASTGAQQPSALAALQPAKERRSSSSS 2536
A DH G+ S + + + E P + G Q+P +L +L
Sbjct: 2457 EAELLVKL---DHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSL------------ 2501
Query: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPP 2596
S ++ SS + ++D + L + P P +++ G P
Sbjct: 2502 -----GSYPPAAGSSEPKAPWPKATDGD-----------LAQEPGPGLTFEDS---GNPK 2542
Query: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS----------------------------- 2627
P A+ ++ + S SSSSSSS SSSSSSS
Sbjct: 2543 SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNC 2602
Query: 2628 -----------SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
SSSSSSSSSSSSSSSSSSSSS S + + +S S
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
Query: 2677 SPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
S S S S + P+P P Q + ++ Q G +R +H +
Sbjct: 2663 SSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATK---QAGKARPSAHSPGK 2719
Query: 2737 ETPSPRP 2743
+TP+P+P
Sbjct: 2720 KTPAPQP 2726
Score = 79.0 bits (193), Expect = 6e-14
Identities = 117/509 (22%), Positives = 170/509 (33%), Gaps = 80/509 (15%)
Query: 255 PKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP-ASGRRG----EGDAP 309
P ++R R TS D+ D + S AK GR PS A G R EG+
Sbjct: 2298 PSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGR---GRKPSAKAKGDRAATLEEGNPT 2354
Query: 310 FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA-TRPSPSPERSSTGPEPPAPTP 368
P T PSS + K P P + + K K + A +PSP+P ++ P P
Sbjct: 2355 DEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAE 2414
Query: 369 LLAERHGGSPQPLATTPLSQE---------------PVNPPSEA------------SPTR 401
L A +P PL T P ++ P P EA SP
Sbjct: 2415 LPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKS 2474
Query: 402 DRS----------------PPKSPEKL----PQSSSSESSPPSPQPTK----------VS 431
++ PKS L P + SSE P P+ T ++
Sbjct: 2475 KKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLT 2534
Query: 432 RHASSSPESPKPAPA--PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489
S +P+SP A A G+ SSS +S S + S S T G
Sbjct: 2535 FEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGG 2594
Query: 490 AKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQ 549
G + R S + S S S+ S S S S S S ++
Sbjct: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2654
Query: 550 RRGRSRSARRGRSHSRSPATRGRSRSR--------TPARRGRSRSRTPARRRSRSRTPTR 601
S S+ S S S S S T ++ T A +++ P+
Sbjct: 2655 SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSA 2714
Query: 602 RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSR 661
+TPA + + P + ++ P + P +R G T R R
Sbjct: 2715 HSPGKKTPA----PQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLP 2770
Query: 662 TPARRGRSRSRTPARRSGRSRSRTPARRG 690
+ R + + PAR+ + + RRG
Sbjct: 2771 SVENRPKIAAFLPARQLWKWFGKPTQRRG 2799
Score = 72.0 bits (175), Expect = 8e-12
Identities = 79/352 (22%), Positives = 131/352 (37%), Gaps = 63/352 (17%)
Query: 150 SFDPQRRAREAKQPAP--------EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE 201
S+ P + E K P P + P P +S + +SP K + ++D SE
Sbjct: 2503 SYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD----KAQAEQDGAEESE 2558
Query: 202 SSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH 261
SSS SS S SE++ + DK T S +
Sbjct: 2559 SSSSSSSGSSSSSSSSSSSGSETEGEEEG-----------DKNGDGGCGTGGRNCSAASS 2607
Query: 262 RSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321
R+ S S+SSS +S S S S+++ + +++ + S S +S S ++S+
Sbjct: 2608 RAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------SSSSSSSSSSS 2658
Query: 322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381
SS +++ SS D+D P+P + GP A P A + G +P
Sbjct: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP-----TAGPSAQAALPTKATKQAGKARPS 2713
Query: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441
A +P K+P PQ+ P PQPT+ + + +
Sbjct: 2714 AHSP-------------------GKKTPAPQPQA-------PPPQPTQPLQPKAQAGAKS 2747
Query: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRG 493
+P G H + + R R K + P+R++ + T +RG
Sbjct: 2748 RPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRG 2799
Score = 66.2 bits (160), Expect = 4e-10
Identities = 108/442 (24%), Positives = 165/442 (37%), Gaps = 66/442 (14%)
Query: 1404 SPVLDAVPRTPSRERSSSASSPEMKDG--------------LPRTPSRRSRSGSSPGLRD 1449
SP L VP R R +S + E KDG R PS +++ + L +
Sbjct: 2292 SPAL-LVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEE 2350
Query: 1450 GSGTPSRHSLS-----GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504
G+ T S S+PG K P P R++ PKA P P+P SP+ P
Sbjct: 2351 GNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKA-----PKARPAPPQP---SPAPPA 2402
Query: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPL-------GQRSRSGSSQELDVKPSASPQERS 1557
+ C P+ +E ++A PL + ++ +++E K P E +
Sbjct: 2403 FTS-CPAPE---PFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEA 2458
Query: 1558 E--------SDSSPDSK-AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
E +SP SK AK LR+ +G E S L +GSS P
Sbjct: 2459 ELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWP 2518
Query: 1609 RAAPR------------AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656
+A SG+ SP+ KA A + S S SSS G S SSS+
Sbjct: 2519 KATDGDLAQEPGPGLTFEDSGNPKSPD-KAQAEQDGAEESESSSSSSS-GSSSSSSSSSS 2576
Query: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET 1716
S E + + G SSR++ + + S S S+SSS +
Sbjct: 2577 SGSETEGEEEGDKNGDGGCGTGGRNCSAA----SSRAASPASSSSSSSSSSSSSSSSSSS 2632
Query: 1717 RSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSR 1776
S + S S SS + S SS S+SS + +T+ S S +
Sbjct: 2633 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
Query: 1777 SRREKTRTTRRRDRSGSSQSTS 1798
+ T+ ++G ++ ++
Sbjct: 2693 PSAQAALPTKATKQAGKARPSA 2714
Score = 58.5 bits (140), Expect = 9e-08
Identities = 75/310 (24%), Positives = 112/310 (36%), Gaps = 54/310 (17%)
Query: 1473 PSRGRSECDSSPEPKA----LPQTPRPR-----SRSPSSPELNNKCLTPQRERSGSESSV 1523
P+ G SE +P PKA L Q P P S +P SP+ Q E+ G+E S
Sbjct: 2506 PAAGSSE-PKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD------KAQAEQDGAEESE 2558
Query: 1524 DQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP 1583
+ S SGSS S+ + E + + T G +
Sbjct: 2559 SSSS---------SSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT-------GGRNC 2602
Query: 1584 EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK 1643
S SP S S SS ++ + S S SS S SSS
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS----------------SSSSSS 2646
Query: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
S SSS+ SS S ++ SS ++ P S + T+ +
Sbjct: 2647 SSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ 2706
Query: 1704 SRRSRSASSSPETRS-----RTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758
+ ++R ++ SP ++ + PP P + KSR ++R P TK ++
Sbjct: 2707 AGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSR-PKKREGVHLPTTKELAK 2765
Query: 1759 RGRSPSPKPR 1768
R R PS + R
Sbjct: 2766 RQRLPSVENR 2775
Score = 57.8 bits (138), Expect = 1e-07
Identities = 111/520 (21%), Positives = 167/520 (32%), Gaps = 60/520 (11%)
Query: 442 KPAPA---PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP---------AT 489
+P+PA P + R S TSK+ G+ ++ GR R P AT
Sbjct: 2290 EPSPALLVPSAKRR--SRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAAT 2347
Query: 490 AKRGRSRSRTP-TKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR--SRSPQRPGWSRSR 546
+ G P T S +P ++S R+++P+ R SP P ++
Sbjct: 2348 LEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFT--- 2404
Query: 547 NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS 606
S A + +PAT S PA PA R + S +
Sbjct: 2405 -------SCPAPEPFAELPAPAT-----SLAPA----PLITMPATRPKPKKARAAEESGA 2448
Query: 607 RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666
+ P R G SP ++++ R P G ++
Sbjct: 2449 KGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED-------PGAGGWQEPKSLLSL 2501
Query: 667 GRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS 726
G S PA S ++ P ++ P G L + ++P +
Sbjct: 2502 G---SYPPAAGSSEPKAPWPKATDGDLAQEPGPG------LTFEDSGNPKSPDKAQAEQD 2552
Query: 727 SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786
+E S +S S S+SS S S R + SS
Sbjct: 2553 GAEESESSSSSS--SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610
Query: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846
S + S S SS + S + S SSSS S + S S SSSS S
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670
Query: 847 GTPPRQGSITSPQANEQSVT--PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP 904
T S +S + T P ++ + + PS HS G P + P
Sbjct: 2671 STTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSP-GKKTPAPQPQAP 2729
Query: 905 PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR 944
P P + QPK +A R + G P+ + R
Sbjct: 2730 P---PQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKR 2766
Score = 57.0 bits (136), Expect = 3e-07
Identities = 102/505 (20%), Positives = 180/505 (35%), Gaps = 62/505 (12%)
Query: 154 QRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKK-DRGRRSESSSPRRERKKS 212
+RR+R+ + E + E +++ +K K K DR E +P E +
Sbjct: 2301 KRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPST 2360
Query: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRR--------AHRST 264
+ S SKK P P KR K R +PAP + A
Sbjct: 2361 PLALEPSSTPGSKKSP---PEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPA 2417
Query: 265 SADSASSSD-----TSRSRSRSAAAKTHTTALAGRSP----------------SPASGRR 303
A S + + +R + + A A + A R P SP S +
Sbjct: 2418 PATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKA 2477
Query: 304 GEGDAPFSEPGTTSTQRPSS--------PETATKQPSSPYEDKDKDKKEKSATRPSPSPE 355
E +PG Q P S P + +P +P+ K A P P
Sbjct: 2478 KEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWP---KATDGDLAQEPGPGLT 2534
Query: 356 RSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ- 414
+G P +P AE+ G +++ S + S +S + + +K
Sbjct: 2535 FEDSG-NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG 2593
Query: 415 ----------SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSH 464
++SS ++ P+ + S +SSS S + + S SSS +S + S
Sbjct: 2594 GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2653
Query: 465 GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524
+ S S + S + ++ + PT +++ P ++ +
Sbjct: 2654 SSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPS 2713
Query: 525 SRSPQRRGRSRSPQRPGWSRSRNTQRRGR--SRSARRGRSHSRSPATRG-RSRSRTPARR 581
+ SP ++ + PQ P ++ Q + + ++S + R P T+ R R P+
Sbjct: 2714 AHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVE 2773
Query: 582 GRSR--SRTPARRRSR-SRTPTRRR 603
R + + PAR+ + PT+RR
Sbjct: 2774 NRPKIAAFLPARQLWKWFGKPTQRR 2798
Score = 55.1 bits (131), Expect = 1e-06
Identities = 118/506 (23%), Positives = 181/506 (35%), Gaps = 75/506 (14%)
Query: 759 SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSS 818
S +L P +K +SR + + + G S+ P ++R +P AK++ R +
Sbjct: 2292 SPALLVPSAKRRSRKTSKDTGEGKDG-GTAGSEEPGAKARGRGRKPSAKAKGD-RAATLE 2349
Query: 819 SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRS-CFESSP 877
P + TP SS+P K KS P +P+A P F S P
Sbjct: 2350 EGNPTDEVPSTPLALE-PSSTPGSK-KSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCP 2407
Query: 878 DPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRS-------H 930
PE + P+ + +P +T P+ +R++ + K P + + H
Sbjct: 2408 APEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE-ESGAKGPRRPGEEAELLVKLDH 2466
Query: 931 SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRL-LPRYSHS-GSSSP--------DTKVK 980
G +SP + R +S L L Y + GSS P D +
Sbjct: 2467 EGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLA 2526
Query: 981 PETPPRQSHSGSISPYPKVKAQTPP-GPSLSGSKSPCPQEKSKDSLVQSCPGSLS----- 1034
E P + S +P KAQ G S S S S S S GS +
Sbjct: 2527 QEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEE 2586
Query: 1035 ----------------LCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQ 1078
A ++++P S SS S +S S +SS
Sbjct: 2587 GDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 1079 SHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRF 1138
S S S S S S +S S SSS E +S S + A+P +G S +
Sbjct: 2647 SSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCS------SDDEAAPAPTAGPSAQ---- 2696
Query: 1139 QSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPES 1198
++ PT + G++R +A S K PQ A P Q P+Q + ++
Sbjct: 2697 ----AALPT-KATKQAGKAR-PSAHSPGKKTPAPQPQAPPPQPTQ-------PLQPKAQA 2743
Query: 1199 SLVFKDTLRTPPRERSGAGSSPETKE 1224
++ P++R G P TKE
Sbjct: 2744 G------AKSRPKKREGV-HLPTTKE 2762
Score = 52.8 bits (125), Expect = 5e-06
Identities = 94/452 (20%), Positives = 152/452 (33%), Gaps = 81/452 (17%)
Query: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGR 680
A+RRSR + S+ + G + S P + R R R P+ + + R G
Sbjct: 2300 AKRRSR------KTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKG-DRAATLEEGN 2352
Query: 681 SRSRTPARR-GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS------------- 726
P+ S TP +S + +R ++ P S +
Sbjct: 2353 PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF 2412
Query: 727 --------------------SSERKNKSRTSQRR-SRSNSSPEMKKSRISSRRSRSLSSP 765
+ + K+R ++ ++ P + + ++SP
Sbjct: 2413 AELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSP 2472
Query: 766 RSKAKSRLSLRRSLSGSSPCPKQKS-----QTPPRRSRSGSSQPKAK------------- 807
+SK L R G+ + KS PP +GSS+PKA
Sbjct: 2473 KSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPA---AGSSEPKAPWPKATDGDLAQEP 2529
Query: 808 --------SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQ 859
S P ++ + ++S++ S S SSS S +G +
Sbjct: 2530 GPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDK 2589
Query: 860 ANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKV 919
+ R+C +S SR S S S SS SS+ S S SSS
Sbjct: 2590 NGDGGCGTGGRNCSAAS------SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 920 KAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKV 979
+ S S S SSS S S +S ++ S S+ E+ P S ++ TK
Sbjct: 2644 SSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA 2703
Query: 980 KPE---TPPRQSHSGSISPYPKVKAQTPPGPS 1008
+ P G +P P+ +A PP P+
Sbjct: 2704 TKQAGKARPSAHSPGKKTPAPQPQA-PPPQPT 2734
Score = 51.6 bits (122), Expect = 1e-05
Identities = 103/504 (20%), Positives = 173/504 (34%), Gaps = 57/504 (11%)
Query: 1549 PSASPQERSESDSSPDSK----AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604
PSA + R S + + K A + P + G P +K + + EV
Sbjct: 2298 PSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEV 2357
Query: 1605 KDKPRAA-PRAQSGSDSSP-EP-----KAPAPRALPRRSRSGSSSKGRGPSPEG-----S 1652
P A P + GS SP EP KAP R P + + P+PE +
Sbjct: 2358 PSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPA 2417
Query: 1653 SSTESSPEH---PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS--PELTRKARLSRRS 1707
+T +P P +R + +R++ E K PRR + +L + S +S
Sbjct: 2418 PATSLAPAPLITMPATRPKPKKARAAEESGAKG---PRRPGEEAELLVKLDHEGVTSPKS 2474
Query: 1708 RSASSS------PETRSRTPPRHRRS-----PSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756
+ A + P P+ S P+ S EP + A P T
Sbjct: 2475 KKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLT 2534
Query: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG 1816
+P P Q + + ++ ++ S SS S+S + + G
Sbjct: 2535 FEDSGNPK-SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG 2593
Query: 1817 GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRS 1876
G G R+ SSR +S P S S S +S + S S +S ++ S
Sbjct: 2594 GCGTGGRN-CSAASSRAAS----------PASSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Query: 1877 RSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR 1936
S + S S S +S S S S +S T S + + P ++
Sbjct: 2643 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD------DEAAPAPTAGPSAQ 2696
Query: 1937 SRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRS 1996
+ PT + + P + P + T P+ + +++ +R + R
Sbjct: 2697 AALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPL---QPKAQAGAKSRPKKRE 2753
Query: 1997 RTS-PVTRRRSRSRTSPVTRRRSR 2019
P T+ ++ + P R +
Sbjct: 2754 GVHLPTTKELAKRQRLPSVENRPK 2777
Score = 44.3 bits (103), Expect = 0.002
Identities = 156/764 (20%), Positives = 259/764 (33%), Gaps = 110/764 (14%)
Query: 1084 PSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK-SGMSPEQSRFQSDS 1142
PSL+S R PV + P++ R P K S M ++ R +
Sbjct: 1416 PSLESLLAAGSHMLREVLDGPVVD-----PLKNLRLPRELKPNKKYSWMRKKEERMYAMK 1470
Query: 1143 SSYPTVDSNSLLGQSRLETAESKEK---------MALPPQEDATASPPRQKDKFSPFPVQ 1193
SS +D+ L + RL + + K ED P R + P
Sbjct: 1471 SSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGP---- 1526
Query: 1194 DRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEK----SEEPA 1249
RP L +PPR+R +G S S L +S D EL + K SEE
Sbjct: 1527 GRPRKRTHAPSAL-SPPRKRGKSGHSSGKLSSKSLL--TSDDYELGAGIRKRHKGSEEEH 1583
Query: 1250 GQILSHLSSELKEMSTSNFESSPE------------VEERPAVSLTLDQSQSQASLEAVE 1297
++ + + + E+S + ++ ++ LD++ S + ++
Sbjct: 1584 DALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLK 1643
Query: 1298 VP----------SMASSWGGPHFSPEHKELS-NSPLRENSFGSPLEFRNSGP-----LGT 1341
P S S G + +P L N G L+ G
Sbjct: 1644 SPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTR 1703
Query: 1342 EMNTGFSSEVK-EDLNGPFLNQLE-----TDPSLDMK--EQSTRSSGHSSSELSPDAVEK 1393
+M GF + + + + PF +++ TD D + + + G SSS+L+P +
Sbjct: 1704 KMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCS 1763
Query: 1394 AGMSSNQSISSPVLD----AVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
++++ P L A PRT + ++S P L +R S S SS D
Sbjct: 1764 MVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLL-LREAEARSSFSDSSEESFD 1822
Query: 1450 GSGTPSRHS----------LSGSSPGMKDIPRTPSRGRSE----------CDSSPEPKAL 1489
+ SG + R S G E + P P
Sbjct: 1823 QDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVG 1882
Query: 1490 PQ---TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQ-RSRSGSSQEL 1545
P + E L + E + SES V K R+P G R + G +
Sbjct: 1883 PSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEV--KVRKRSPAGLLRPKKGLGEPG 1940
Query: 1546 DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVK 1605
+ +P R SSPD KAK +++R K R P+ + PE
Sbjct: 1941 PSLAAPTPGARGPDPSSPD-KAKLAVEKGRKAR---------KLR-GPKEPGFEAGPEAS 1989
Query: 1606 DKPRAAPRAQSG---SDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662
D R D+S APAP + +++ +KG SP + + P
Sbjct: 1990 DDDLWTRRRSERIFLHDASAA--APAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDP 2047
Query: 1663 PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPP 1722
K + + + P ++ P + + LT R +++ E R +
Sbjct: 2048 RKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGA 2107
Query: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
+ S+++ E E ++ S PR R +P+P+
Sbjct: 2108 VSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAV-ERPLTPAPR 2150
Score = 44.3 bits (103), Expect = 0.002
Identities = 46/190 (24%), Positives = 67/190 (35%), Gaps = 22/190 (11%)
Query: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS-------SSGSS- 2559
+P +T +QP L L+ A+ R S S SS S SS +SG
Sbjct: 1789 KPKPATSRKQPFCLL-LREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGY 1847
Query: 2560 ---------SSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSS 2610
S E S L + A +PSPT P +V + + K +R+S
Sbjct: 1848 RLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLG 1907
Query: 2611 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
+ + S S S + S ++P+P GP P+SP K
Sbjct: 1908 TEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPD----PSSPDKAKL 1963
Query: 2671 GERRSRSPRK 2680
+ R RK
Sbjct: 1964 AVEKGRKARK 1973
Score = 43.1 bits (100), Expect = 0.004
Identities = 55/246 (22%), Positives = 94/246 (38%), Gaps = 36/246 (14%)
Query: 2451 VPSAFSDQSRCLIAQTTPVAGSQSLSS-GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
+ + +S Q RCL T V G L G + T GD +P + H + P
Sbjct: 2230 IAAYWSQQYRCLYPGTV-VRGLLDLEDDGDLITVEFDDGDTG---RIP---LSHIRLLPP 2282
Query: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS--------------SSSSS 2555
+PS A L P+ +RRS +S + ++ S S+ +
Sbjct: 2283 DYKIQCAEPSP-ALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAK 2341
Query: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
+++ EG+ P L PS TP K++ PPEP + K + +
Sbjct: 2342 GDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKS-----PPEPVDKRAK------APKAR 2390
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRS 2675
+ S + + +S + + + ++S +P+P P PKP K E +
Sbjct: 2391 PAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKP--KKARAAEESGA 2448
Query: 2676 RSPRKP 2681
+ PR+P
Sbjct: 2449 KGPRRP 2454
Score = 42.0 bits (97), Expect = 0.008
Identities = 65/330 (19%), Positives = 115/330 (34%), Gaps = 50/330 (15%)
Query: 162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE 221
+PA +P+ L+ + +RS ++ +D E E + + +R
Sbjct: 1791 KPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLG 1850
Query: 222 SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRS 281
+ + R+ +P + + + S P+P + ++ + R
Sbjct: 1851 A-----RERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSL 1905
Query: 282 AAAKTHTT----ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
+ T + R SPA R + EPG + +P PSSP D
Sbjct: 1906 LGTEFEYTDSESEVKVRKRSPAGLLRPKKG--LGEPGPSLAA--PTPGARGPDPSSP--D 1959
Query: 338 KDK---DKKEKSATRPSPSPERSSTGPEPP---------APTPLLAERHGGSPQPLATTP 385
K K +K K+ P GPE + L + +P P++T P
Sbjct: 1960 KAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAP 2019
Query: 386 LSQE-------PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
++ P++P +A +DR P+ +K ++ PP +P
Sbjct: 2020 ATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPP-----------PRAP 2068
Query: 439 ESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
P A AP +SS T+ RS +AK
Sbjct: 2069 ALPSEARAPH-----ASSLTAAKRSKAKAK 2093
Score = 41.6 bits (96), Expect = 0.011
Identities = 103/499 (20%), Positives = 164/499 (32%), Gaps = 71/499 (14%)
Query: 1065 PDHRSDTSSPE----VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRS--PIRQDR 1118
PD++ + P V + S + GG + S P + R P + +
Sbjct: 2282 PDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAK 2341
Query: 1119 GEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATA 1178
G+ +A+ L+ G +P + + P+ S +K A P +
Sbjct: 2342 GDRAAT--LEEG-NPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSP 2398
Query: 1179 SPPRQKDKFSPFPVQDRPESS-------LVFKDTLRTPPR-----ERSGAGSSPETKEQN 1226
+PP +P P + P + L+ R P+ E SGA E+
Sbjct: 2399 APPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEA 2458
Query: 1227 SALP-------TSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPE------ 1273
L TS + ++ E + E+P S L S S E
Sbjct: 2459 ELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWP 2518
Query: 1274 ------VEERPAVSLTLDQSQSQASLE--------AVEVPSMASSWGGPHFSPEHKELSN 1319
+ + P LT + S + S + A E S +SS G S+
Sbjct: 2519 KATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGS---------SS 2569
Query: 1320 SPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSS 1379
S +S GS E G + G N + P+ S+ SS
Sbjct: 2570 SSSSSSSSGSETEGEEEGDKNGDGGCGTGGR-----NCSAASSRAASPASSSSSSSSSSS 2624
Query: 1380 GHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRS 1439
SSS S + + SS+ S SS + + S SSS+SS D S S
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD---EDSSCSS 2681
Query: 1440 RSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRS 1499
++P G + + K P S G+ +P P+ PQ P P+
Sbjct: 2682 DDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGK----KTPAPQ--PQAPPPQPTQ 2735
Query: 1500 PSSPELNNKCLTPQRERSG 1518
P P+ + ++R G
Sbjct: 2736 PLQPKAQAGAKSRPKKREG 2754
Score = 40.8 bits (94), Expect = 0.019
Identities = 66/288 (22%), Positives = 103/288 (35%), Gaps = 41/288 (14%)
Query: 176 ESSSSRSPTPKQKKKK---------KKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
+ SSSR K++ + KK R R E+S PR + E+ ++
Sbjct: 197 KGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQ-------EARAEG 249
Query: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSAD---SASSSDTSRSRSRSAA 283
R+ R P ++R S ++++ P + D A ++ R ++ AA
Sbjct: 250 RQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAA 309
Query: 284 AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKK 343
+ L R+ + G R +P P + P +P AT P+ Y + +
Sbjct: 310 RQDEGARLLRRTETLLPGPR-PCPSPLPPP-PAPPKGPPAPPAAT--PAGVYTVFREQGR 365
Query: 344 EKSATRPS--PSPERSSTGPEP-----PAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396
E P+ PS E P P A ER G P L P S P++ P
Sbjct: 366 EHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEG 425
Query: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA 444
EK S + PP+ PT + AS P + PA
Sbjct: 426 LR-----------EKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPA 462
Score = 40.4 bits (93), Expect = 0.024
Identities = 154/753 (20%), Positives = 250/753 (33%), Gaps = 110/753 (14%)
Query: 34 PDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQ------QI 87
P G + L +LEAA L H E+ LELE +E G E+ +
Sbjct: 1360 PGAAGAQALEKLEAAESLVLEQSFL-HGITLLSEIAELELERRSQEMGGAERALVARPSL 1418
Query: 88 QEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVD 147
+ +A ML E P + P + ++ KK ER+ + + S D
Sbjct: 1419 ESLLAAGSHMLREVLDGPVVDPLKNLRLPRELKPNKKYSWMRKKEERM---YAMKSSLED 1475
Query: 148 GSSFDPQRRAREAKQPAPEPPKPYSLV----RESSSSRSPTPKQKKKKKKKDRGRRSESS 203
+ + R R A+ K LV R S R P + ++ R R+ +
Sbjct: 1476 MDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHA 1535
Query: 204 ----SPRRERKKSSK----------------------KKKHRSESESK-------KRKHR 230
SP R+R KS +K+H+ E K + R
Sbjct: 1536 PSALSPPRKRGKSGHSSGKLSSKSLLTSDDYELGAGIRKRHKGSEEEHDALIGMGKARGR 1595
Query: 231 SPTPKSKRKSKD--------KKRKRSRSTTPAPKSRRAHRSTSADSASS----SDTSRSR 278
+ T S D KK+ S A K +A T D S SD++ +
Sbjct: 1596 NQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGK 1655
Query: 279 SRSAAA-------------KTHTTALAGRSPSPASGRRGEGDAPFS----EPGTTSTQRP 321
S+++ K G S S R G+ E G + +P
Sbjct: 1656 SKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQP 1715
Query: 322 SSPETATKQPSSPYE---DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSP 378
S + S Y D ++D++ P+ P S P + G P
Sbjct: 1716 KSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGP 1775
Query: 379 QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
+ L L+ P A+ + E +SS S+SS S + S
Sbjct: 1776 K-LTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEE 1834
Query: 439 ESPKPAPAPGSH-----REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRG 493
E + A G RE + SP + G R + S PS +G S S +
Sbjct: 1835 ELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAA-SALPSPTVGPSLSVVQLE-A 1892
Query: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553
+ ++R +R ++ S S + R RSP R + + G
Sbjct: 1893 KQKARKKEERQSLLGTEFEYTDSESEVKV-RKRSPAGLLRPK----------KGLGEPGP 1941
Query: 554 SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR-------RRSRSRTPTRRRSRS 606
S +A + P++ +++ R + R P S TRRRS
Sbjct: 1942 SLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSE- 2000
Query: 607 RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666
R + + P T++ + SP + +GR++ R R+ +
Sbjct: 2001 RIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGA 2060
Query: 667 GRSRSRTPA----RRSGRSRSRTPARRGRSRSR 695
G R PA R+ + S T A+R +++++
Sbjct: 2061 GLPPPRAPALPSEARAPHASSLTAAKRSKAKAK 2093
Score = 39.7 bits (91), Expect = 0.041
Identities = 54/268 (20%), Positives = 86/268 (32%), Gaps = 7/268 (2%)
Query: 1329 SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSP 1388
+P G L E G + E + P Q E D + + + S+ SSG SSS S
Sbjct: 2515 APWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSS 2574
Query: 1389 DAV--EKAGMSSNQSISSPVLDAVPRTPSR--ERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
+ E G R S R++S +S + S S S SS
Sbjct: 2575 SSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSS 2634
Query: 1445 PGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504
S + S S S SS + S S ++ E + + P
Sbjct: 2635 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694
Query: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564
T +++G +TP Q ++P A +S
Sbjct: 2695 AQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREG 2754
Query: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLS 1592
T L +R R P V+++ +++
Sbjct: 2755 VHLPTTKELAKRQR---LPSVENRPKIA 2779
Score = 38.5 bits (88), Expect = 0.092
Identities = 31/150 (20%), Positives = 60/150 (40%), Gaps = 6/150 (4%)
Query: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
++ T K+ G A+ + R S+ + +++ + + S+ +
Sbjct: 2305 RKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLAL 2364
Query: 2637 SSSSSSSSSSSSPSPAKP---GPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
SS+ S S P P P+A P P P PP +P + + SL+
Sbjct: 2365 EPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAP 2424
Query: 2694 SPVERRRPSPQPSPRDQQSS--SSERGSRR 2721
+P+ P+ +P P+ +++ S +G RR
Sbjct: 2425 APL-ITMPATRPKPKKARAAEESGAKGPRR 2453
Score = 36.2 bits (82), Expect = 0.46
Identities = 74/347 (21%), Positives = 125/347 (36%), Gaps = 88/347 (25%)
Query: 74 EEMMEEQGYEEQQIQEKVAT---FRLMLLEKDVNPGGKEE--------------TPGQRP 116
+E EE+ EE+ +E A+ +RL E+ ++PG +E +P P
Sbjct: 1824 DESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGP 1883
Query: 117 AVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEP----PKPYS 172
+++ A+ +K E ++ G Y D S R+ A P+ P P S
Sbjct: 1884 SLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGP-S 1942
Query: 173 LVRESSSSRSPTPK---------QKKKKKKKDRG--------------------RRSE-- 201
L + +R P P +K +K +K RG RRSE
Sbjct: 1943 LAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERI 2002
Query: 202 -------------SSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRS 248
S++P + + +K ++ + K R K RK K K
Sbjct: 2003 FLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDR----KDPRKKKKGKEAGP 2058
Query: 249 RSTTPAPKS---RRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG------RSPSPA 299
+ P P++ R+ A S +++ S+++++ K G S +
Sbjct: 2059 GAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAE 2118
Query: 300 SGRRGEGDAPFSE----PGTTSTQRPSSPETATKQPSSPYEDKDKDK 342
D+ FSE P + +RP +P P S DKD+ K
Sbjct: 2119 EDFEPNQDSSFSEDEHLPRGGAVERPLTP-----APRSCIIDKDELK 2160
Score = 35.4 bits (80), Expect = 0.78
Identities = 92/478 (19%), Positives = 158/478 (33%), Gaps = 52/478 (10%)
Query: 1731 SSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDR 1790
+ P PA S++RR +S T G + S +P R R R K + DR
Sbjct: 2289 AEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKG----DR 2344
Query: 1791 SGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRK 1850
+ + + + + + + GS +SP R + + R P +
Sbjct: 2345 AATLEEGNPTDEVPSTPLALEPSSTPGS---KKSPPEPVDKRAKAPKARPAPPQPSPAPP 2401
Query: 1851 RSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR 1910
S +P P+ +PAT S + PLI+ +R + P R + + RR
Sbjct: 2402 AFTSCPAPEPFAEL---PAPAT---SLAPAPLITMPATRPK--PKKARAAEESGAKGPRR 2453
Query: 1911 SRSRASPVSRRRSRSRTPPVTRRRSRS------------RTPTTRRRSRSRTPPVTRRRS 1958
A + + T P +++ + + P + S P
Sbjct: 2454 PGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEP 2513
Query: 1959 RSRTPPVTRRRSRSRTSP-ITRRRSRSRTSPVTRR-------RSRSRTSPVTRRRSRSRT 2010
++ P T P +T S + SP + S S +S + S S +
Sbjct: 2514 KAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSS 2573
Query: 2011 SPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTR 2070
S + + T + SR+ S S + ++ S +
Sbjct: 2574 SSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSS 2633
Query: 2071 SPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRC 2130
S + S+S SSS S S++ ++ + S S + + SC S +P P
Sbjct: 2634 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP---- 2689
Query: 2131 RSPGMLEPLGSSRTPMSVLQQAG---------GSMMDGPGPRIPDHQRTSVPENHAQS 2179
P + P +QAG G P P+ P Q T + AQ+
Sbjct: 2690 ----TAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQA 2743
Score = 35.4 bits (80), Expect = 0.78
Identities = 50/209 (23%), Positives = 63/209 (30%), Gaps = 37/209 (17%)
Query: 143 DSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSES 202
D DG R A A P S SSSS S S S
Sbjct: 2588 DKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS-----------------SSS 2630
Query: 203 SSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHR 262
SS SS S S S S + S S S STT
Sbjct: 2631 SS-------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDS------ 2677
Query: 263 STSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPS 322
S S+D ++ + S AA T T AG++ R +P + Q P
Sbjct: 2678 SCSSDDEAAPAPTAGPSAQAALPTKATKQAGKA-------RPSAHSPGKKTPAPQPQAPP 2730
Query: 323 SPETATKQPSSPYEDKDKDKKEKSATRPS 351
T QP + K + KK + P+
Sbjct: 2731 PQPTQPLQPKAQAGAKSRPKKREGVHLPT 2759
Score = 35.0 bits (79), Expect = 1.0
Identities = 45/215 (20%), Positives = 71/215 (33%), Gaps = 10/215 (4%)
Query: 246 KRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGE 305
+RS + HR+ + S + ++ A L + P A+G G
Sbjct: 927 QRSAQLVQERLKAQEHRAEMEEKGSKRGLEAA-GKAGLATAGPGLLPRKPPGLAAGPAGT 985
Query: 306 GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA 365
S P + P + A + + +D K A +PS +S P P
Sbjct: 986 YGKAVSPPPS-----PRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPP 1040
Query: 366 PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
PTP + + + L E PS PP+ P + P
Sbjct: 1041 PTPGITRKEEAPENVVEKKDLELEK-EAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLL 1099
Query: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSK 460
QPT + +P+ P PA P ++ SP K
Sbjct: 1100 QPTAAADADGLAPDVPLPADGP---ERLALSPEDK 1131
Score = 34.7 bits (78), Expect = 1.3
Identities = 40/163 (24%), Positives = 58/163 (35%), Gaps = 15/163 (9%)
Query: 2070 RSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDR 2129
R+ A R+AS +SS S S++ ++ + S S + + +SS S S S S +
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---- 2655
Query: 2130 CRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAIS 2189
SS + S + S D D + P ++ AL A
Sbjct: 2656 ----------SSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATK 2705
Query: 2190 -LGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASR 2231
G ARP A Q P P P L+ A SR
Sbjct: 2706 QAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSR 2748
Score = 33.1 bits (74), Expect = 3.9
Identities = 30/128 (23%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 2123 SPTPLDRCRSPGMLEPLGSSRTPMSVLQQAG-GSMMDGPGPRIPDHQRTSVPENHAQSRI 2181
+P+P C G+LE S T S + + ++GP PR+ RT
Sbjct: 1189 TPSPAGGCGG-GLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEP--------- 1238
Query: 2182 ALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMN 2241
A+ LG P ++ + A+ V PV + + P LA P+ S +
Sbjct: 1239 --CTAALDLGVQLTPETL----VEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLE 1292
Query: 2242 LASARTPA 2249
++ PA
Sbjct: 1293 MSDCDVPA 1300
Score = 33.1 bits (74), Expect = 3.9
Identities = 135/630 (21%), Positives = 212/630 (33%), Gaps = 100/630 (15%)
Query: 906 RQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLP 965
R+ P R A+ PR+R SG SS S S+S+ + E
Sbjct: 1523 RRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLS----------SKSLLTSDDYELGAGI 1572
Query: 966 RYSHSGSSSPDT------KVKPETPPRQSHSGS---ISPYPKVKAQTPPGPSLSGSKSPC 1016
R H GS K + H S IS K + SK
Sbjct: 1573 RKRHKGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDK 1632
Query: 1017 PQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS------PDHRSD 1070
+K ++S P S AG KS T G + L G+++ + +S
Sbjct: 1633 ALSLTKQDKLKS-PFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSS 1691
Query: 1071 TSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSG 1130
R + + + K++ PK S +S V+ + + +D EF G
Sbjct: 1692 REGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDE-EFLKDEWPAQG 1750
Query: 1131 MSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPF 1190
P S+ ++ G +L +K +A P T P + PF
Sbjct: 1751 --PSSSKLTPSLLCSMVAKNSKAAGGPKL----TKRGLAAP----RTLKPKPATSRKQPF 1800
Query: 1191 PVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAG 1250
+ LR S + SS E+ +Q+ SS++E+ E +E+ +E +G
Sbjct: 1801 CL------------LLREAEARSSFSDSSEESFDQDE----SSEEEDEEEELEEEDEASG 1844
Query: 1251 QILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHF 1310
L + + +S ES + R A S L SL V++ + +
Sbjct: 1845 GGY-RLGARERALSPGLEESGLGLLARFAAS-ALPSPTVGPSLSVVQLEAKQKA----RK 1898
Query: 1311 SPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLD 1370
E + L + S ++ R P G L P E PSL
Sbjct: 1899 KEERQSLLGTEFEYTDSESEVKVRKRSPAG--------------LLRPKKGLGEPGPSLA 1944
Query: 1371 MKEQSTRSSGHSSSELSPDAVEKAGMSSN-QSISSPVLDAVPRTP-----SRERS----- 1419
R SS + + AVEK + + P +A P +R RS
Sbjct: 1945 APTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFL 2004
Query: 1420 --SSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGR 1477
+SA++P P T + R G G S +G + KD PR +G+
Sbjct: 2005 HDASAAAPAPVSTAPATKTSRCAKG---------GPLSPRKDAGRAKDRKD-PRKKKKGK 2054
Query: 1478 SECDSS--PEPKALPQTPRPRSRSPSSPEL 1505
+ P P+A P P +R+P + L
Sbjct: 2055 EAGPGAGLPPPRA-PALP-SEARAPHASSL 2082
Score = 32.3 bits (72), Expect = 6.6
Identities = 57/272 (20%), Positives = 98/272 (36%), Gaps = 47/272 (17%)
Query: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS 713
++ R + + G T + + R R+PA R + G S +
Sbjct: 1894 QKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLA--------- 1944
Query: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRSRS---------NSSPEMKKSRISSRR------ 758
+ TP RG SS ++ + R++R + PE + +RR
Sbjct: 1945 -APTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIF 2003
Query: 759 ----SRSLSSPRSKAK----SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRT 810
S + +P S A SR + LS + K + PR+ + G
Sbjct: 2004 LHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLP 2063
Query: 811 PPRR-SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT---SPQANEQSVT 866
PPR + S + P S T +++S + + +VK + G+++ A E+
Sbjct: 2064 PPRAPALPSEARAPHASSLTAAKRS-KAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFE 2122
Query: 867 PQRRSCFESSPDPEL-------KSRTPSRHSC 891
P + S F S D L + TP+ SC
Sbjct: 2123 PNQDSSF--SEDEHLPRGGAVERPLTPAPRSC 2152
Score = 32.3 bits (72), Expect = 6.6
Identities = 27/118 (22%), Positives = 47/118 (39%), Gaps = 16/118 (13%)
Query: 2597 EPTPA------KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
EP+PA KR+ R +S + ++ S + + S+ + +++
Sbjct: 2290 EPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLE 2349
Query: 2651 PAKPGPQALPKP-ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
P + P A PG ++S P +P+D + +P R P PQPSP
Sbjct: 2350 EGNPTDEVPSTPLALEPSSTPGSKKS--PPEPVD------KRAKAPKARPAP-PQPSP 2398
Score = 32.0 bits (71), Expect = 8.6
Identities = 79/371 (21%), Positives = 119/371 (32%), Gaps = 75/371 (20%)
Query: 2340 GP-RSAHATAPVNIAG-----SRTAAALA---PASLTSARMAPALSGANLTSPRVPLSAY 2390
GP RS H P ++G R AA A PAS + P A L P A+
Sbjct: 7 GPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAF 66
Query: 2391 ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQ------ 2444
L S PSA S P PS ++P+ S LP Q
Sbjct: 67 ----------LGSFVASGMGPSASSHG----SPVPLPSDLSFRSPTPSNLPMVQLWAAHA 112
Query: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
+ S +PS L P +GS LS + P + +
Sbjct: 113 HEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQ------------------LGQPSIFDT 154
Query: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
G+ P G P+A A P + S+ + SS + + SSS G + +
Sbjct: 155 QKGQGPGGDGFYLPTAGA---PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAG 211
Query: 2565 GSSLPV------QPEVALKRVPSP---TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
P P + P +EA EGR P +R S + S +
Sbjct: 212 RGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKT 271
Query: 2616 SSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSSSSSPSPAK---------PGPQAL 2659
+++ S + + + + + + ++ A+ PGP+
Sbjct: 272 KNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPC 331
Query: 2660 PKPASPKKPPP 2670
P P P PP
Sbjct: 332 PSPLPPPPAPP 342
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 120 bits (301), Expect = 2e-26
Identities = 352/1593 (22%), Positives = 549/1593 (34%), Gaps = 312/1593 (19%)
Query: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK 1022
LL R + DT V+ E P ++ + + K++A K P S
Sbjct: 441 LLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRALV----RAHSEKDQPPFGDSD 496
Query: 1023 DSLV--QSCPG----------SLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSD 1070
DS+ +S PG ++ + V+ PPG + + Q+ + D ++
Sbjct: 497 DSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKKHQVSVEGTNQTDVKAV 556
Query: 1071 TSSPEVRQ-SHSESPSLQSKSQTSPKGGRSRSSSPVTELA-SRSPIRQDRGEFSASPMLK 1128
++ S E+ L +T + G S ++S V ++ S+ P D G A+ +LK
Sbjct: 557 GGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLK 616
Query: 1129 SGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFS 1188
E A PP P ++ +
Sbjct: 617 Q------------------------------ERAHEVGAQGGPPVAQVEQDLPISRENLT 646
Query: 1189 PFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEP 1248
V DTL G S + + + + +PT + E+ + + SE+
Sbjct: 647 DLVVDT---------DTL----------GESTQPQREGAQVPTGREREQHVGGTKDSEDN 687
Query: 1249 AGQILSHLSSELKEMSTSNF------ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMA 1302
G S +L +T F E+ +E+ P + L Q PS
Sbjct: 688 YGD-----SEDLDLQATQCFLENQGLEAVQSMEDEPTQAFMLTPPQELG-------PSHC 735
Query: 1303 SSWGGPHFSPEHKELSNSP--LRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFL 1360
S + L+ P LRE+ E + P T + + GP L
Sbjct: 736 SFQTTGTLDEPWEVLATQPFCLRES------EDSETQPFDTHL----------EAYGPCL 779
Query: 1361 NQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRT-PSR--- 1416
+ P +Q S H+ P ++ G + + + R P R
Sbjct: 780 SPPRAIPG----DQHPESPVHTE----PMGIQGRGRQTVDKVMGIPKETAERVGPERGPL 831
Query: 1417 ERSSSASSPEMKDGLPR----TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT 1472
ER + PE + + T ++ R RD S + +SP + R
Sbjct: 832 ERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASP---ERDRE 888
Query: 1473 PSRGRSECDSSPEPKALPQTPRPRS---RSPSSPELNNKCLTPQRERSGSESSVDQKTVA 1529
+ E + K + + P R P N +C + E + +++ T
Sbjct: 889 SLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQR 948
Query: 1530 RTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589
P G SQ D K AS + D T P+ S+SG S
Sbjct: 949 GEP------EGGSQ--DQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRG-----S 995
Query: 1590 RLSPRRSRSG------SSPEVKDKPRAAPRAQSGSDSSPE-------PKAPAPRALPRRS 1636
+SPRR + G E + RAA + G SP+ P+APAP P S
Sbjct: 996 PVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNS 1055
Query: 1637 RSG----------------------SSSKGRGPSPEGSSSTESSPEHP-PKSRTARRGSR 1673
+S + G +PE S+E P HP PK RT R+ SR
Sbjct: 1056 QSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRT-RKSSR 1114
Query: 1674 SSPEPKTKSRTPPRRRSSRS---SPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV 1730
+P P T + P +S + +P+ T +A SR +RS+ +PE T P + S S
Sbjct: 1115 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTST 1174
Query: 1731 SSPEPAE-KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
P +E S+ +R R+S SS +T T P LQ S S D
Sbjct: 1175 DQPVTSEPTSQVTRGRKSRSSVKTPET------VVPTALELQPSTS------------TD 1216
Query: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSR 1849
R +S+ TS+ + ++RS V + +P Q S+ T + R
Sbjct: 1217 RPVTSEPTSQATRGRKNRSSV----KTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGR 1272
Query: 1850 KRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRT--SPVSRRRSRSRTSVT 1907
K S +P P + P+T R TP + R +RSRT S V + T+
Sbjct: 1273 KNRSSVKTPEPVVPTAPELRPST-STDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPE 1331
Query: 1908 RRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRR--RSRSRTPPV 1965
+ S S PV TP T R +RSRT + ++ T P+ S S PV
Sbjct: 1332 LQISTSTDQPV--------TPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPV 1383
Query: 1966 TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPA 2025
T + SR + + RS +T P T + + P T P T + +R RT +
Sbjct: 1384 TPEPT-SRATRGRKNRSSGKT-PETLVPTAPKLEPSTSTDQPVTPEP-TSQATRGRTNRS 1440
Query: 2026 IRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSP----PAIRRRSAS 2081
+ + P P + + + + S+ R R RS ++P P AS
Sbjct: 1441 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATR-GRTDRSSVKTPETVVPTAPELQAS 1499
Query: 2082 GSS----SDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSP-TPLDRCRSPGML 2136
S+ + S T +N S +TP + ++ S + P TP R+
Sbjct: 1500 ASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGR 1559
Query: 2137 EPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP 2196
S +TP S++ P P+ Q ++ SR L P
Sbjct: 1560 TNRSSVKTPESIV------------PIAPELQPST-------SRNQL---------VTPE 1591
Query: 2197 PSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNL 2256
P+ A S V P P++ P ++ P +T N
Sbjct: 1592 PTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKT-------NR 1644
Query: 2257 ADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALA-------AL 2309
+ +TP V P+A +L +P TPT +V TP A+A
Sbjct: 1645 SSVKTP------------KPVEPAASDL-EPFTPTDQSV------TPEAIAQGGQSKTLR 1685
Query: 2310 SLTGSGTP-PTAANYPSSSRTPQAPASANLVGP----RSAHATAPVNIAG----SRTAAA 2360
S T P PT + S T Q + + P R A P ++A +A
Sbjct: 1686 SSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAP 1745
Query: 2361 LAPASLTS--ARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLD---RARSRTPPSAPS 2415
L P S S R + +LT+ P SP LL+ A
Sbjct: 1746 LEPKSQASRNQRWGAVRAAESLTAIPEP----------ASPQLLETPIHASQIQKVEPAG 1795
Query: 2416 QSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPR 2448
+SR T E P S ++ + PP Q QP+
Sbjct: 1796 RSRFTPELQPKASQSRKRSLATMDSPPHQKQPQ 1828
Score = 105 bits (263), Expect = 5e-22
Identities = 228/1023 (22%), Positives = 370/1023 (36%), Gaps = 162/1023 (15%)
Query: 35 DYKGEEELR-----RLEAALVKRPNPDILDHERKRRVELRCLELE-EMMEEQGYEEQQIQ 88
D GEEEL R + L+ R D E + E E + E ++ + ++IQ
Sbjct: 845 DVTGEEELTKGKQDREQKQLLAR---DTQRQESDKNGESASPERDRESLKVEIETSEEIQ 901
Query: 89 EKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDG 148
EK ++K P E +RP AEL EK + + G
Sbjct: 902 EKQ-------VQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGG 954
Query: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE 208
S Q + +A P PEP + +S+ P+ Q G R SPRR
Sbjct: 955 S----QDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQS--------GGRGSPVSPRRH 1002
Query: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268
+K K +E S+ R + + ++S D + PAP + + +
Sbjct: 1003 QKGLLNCKMPPAEKASRIRAAEKVS-RGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHL 1061
Query: 269 A--------------SSSDTSRSRSRSAAAKTHTTALAGRSPSPA-SGRRGEGDAPFSEP 313
A + T + S+ A ++ L P P R+ PF P
Sbjct: 1062 APPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPF--P 1119
Query: 314 GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373
T++ P P T+T QP +P K ATR S + S PEP PT +
Sbjct: 1120 ATSAAPEPH-PSTSTAQPVTP-------KPTSQATR-SRTNRSSVKTPEPVVPTAPELQP 1170
Query: 374 HGGSPQPLATTPLSQEPVNPPSEAS-PTRDRSPPKSPEKLPQSSSSE--SSPPSPQPTKV 430
+ QP+ + P SQ S +S T + P + E P +S+ +S P+ Q T+
Sbjct: 1171 STSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRG 1230
Query: 431 SRHASS-------SPESPKPAPAPGSHREISSSPT------SKNRSHGR----------- 466
++ SS P +P+ P+ + + ++S PT KNRS +
Sbjct: 1231 RKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPE 1290
Query: 467 ----AKRDKSHSHTPSRRMGRSR-------SPATAKRGRSRSRTPTKRGHSRSRSPQWRR 515
D+ + P+ R RSR +P T + T + P R
Sbjct: 1291 LRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRT 1350
Query: 516 SRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR------RGRSRSARRGRSHSRSPAT 569
+RS ++P+ S P P S +T++ R+ R+ RS ++P T
Sbjct: 1351 TRSRTNMSSVKNPE----STVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPET 1406
Query: 570 RGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP--------- 620
+ + + TP PT + +R RT RS +TP
Sbjct: 1407 LVPTAPKLEPSTSTDQPVTP--------EPTSQATRGRT----NRSSVKTPETVVPTAPE 1454
Query: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGR 680
+ + T PV S++ R+ RS +TP P + + + P
Sbjct: 1455 LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPE---TVVPTAPELQASASTDQPVTSEPT 1511
Query: 681 SRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRR 740
SR+ T R+ RS +TP + L + S + S ++ R N+S
Sbjct: 1512 SRT-TRGRKNRSSVKTPETVVPAAPEL-QPSTSTDQPVTPEPTSRATRGRTNRSSVKTPE 1569
Query: 741 SRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG 800
S +PE++ S +SR P S+A + R S+ P + P S
Sbjct: 1570 SIVPIAPELQPS--TSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQ 1627
Query: 801 SSQPKAKSRTPPRRSRSSSSPPPKQ--------KSKTPSRQS----------HSSSSPHP 842
PK SR R++ SS PK + TP+ QS S +
Sbjct: 1628 PVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSS 1687
Query: 843 KVKSGTPPRQGSITSPQANEQSVTPQ---RRSCFE---SSPDPELKSRTPSRHSCSGSSP 896
V++ P SP +Q ++P+ + SC + ++ +P + CS
Sbjct: 1688 TVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLE 1747
Query: 897 PRVKSSTPPRQSPSRSSS-----PQPKVKAII-SPRQRSHSGSSSPS-PSRVTSRTTPRR 949
P+ ++S R R++ P+P ++ +P S P+ SR T P+
Sbjct: 1748 PKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKA 1807
Query: 950 SRS 952
S+S
Sbjct: 1808 SQS 1810
Score = 87.4 bits (215), Expect = 2e-16
Identities = 234/1132 (20%), Positives = 392/1132 (34%), Gaps = 144/1132 (12%)
Query: 1663 PKSRTARRGSRSSP-EPKTKSRTPPRRRSSRSSPELTR-------KARLSRRSRSASSSP 1714
PK R G P E +T+ P R+ ELT+ K L+R ++ S
Sbjct: 817 PKETAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDK 876
Query: 1715 ETRSRTPPRHRRSPSVSSPEPAE-KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRS 1773
S +P R R S V E + + +++ S + R + P L+
Sbjct: 877 NGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEK 936
Query: 1774 RSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRT 1833
+ E R T+R + G SQ Q+ ++ S G + A S
Sbjct: 937 VPKVILE--RDTQRGEPEGGSQD-----QKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQ 989
Query: 1834 SSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS--------------- 1878
S R G +P +K + P K SR RA+ R +
Sbjct: 990 SGGR--GSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPA 1047
Query: 1879 --RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA-----SPVSRRRSRSRTPPVT 1931
+ PL S+ + P+ S R+ + + +P+S P
Sbjct: 1048 PPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKI 1107
Query: 1932 RRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTR 1991
R R SR S + P + ++ TP T + +RSRT+ R S PV
Sbjct: 1108 RTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTN----RSSVKTPEPVVP 1163
Query: 1992 RRSRSRTSPVTRRRSRSR-TSPVTR-RRSRS--RTPPAIRRRSRSRTPLLPRKRSRSRSP 2047
+ S T + S TS VTR R+SRS +TP + + P R + P
Sbjct: 1164 TAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEP 1223
Query: 2048 LAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS---GSSSDRSRSATPP--ATR---NH 2099
+ R R RS ++P + + +S+D+ ++ P ATR N
Sbjct: 1224 TSQATRGRKN--------RSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR 1275
Query: 2100 SGSRTP-PVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAG----G 2154
S +TP PV + + + TP R+ + S +TP +V+ A
Sbjct: 1276 SSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQIS 1335
Query: 2155 SMMDGPGPRIPDHQRTSVPENHAQSRIALALTAI------SLGTARP-PPSMSAAGLAAR 2207
+ D P P + T N + + + I S T +P P ++ R
Sbjct: 1336 TSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGR 1395
Query: 2208 MSQVPAPVPLMSLRTAPAANLASRIPA---------ASAAAMNLASARTP--AIPTAVNL 2256
++ P + TAP ++ A+ N +S +TP +PTA L
Sbjct: 1396 KNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPEL 1455
Query: 2257 ADSRTPAAAAAMNLASPRTAVAPSAVNLADPRT--PTAPAVNL-AGARTPAALAALSLTG 2313
S + S T ++ P T PTAP + A P S T
Sbjct: 1456 QPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTT 1515
Query: 2314 SGTPPTAANYPSSSRTPQAPA---SANLVGPRSAHATAPVNIAGSRTAAALAPASLT--S 2368
G ++ + P AP S + P + T+ + ++ P S+ +
Sbjct: 1516 RGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIA 1575
Query: 2369 ARMAPALSGANLTSP----RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS---RMTS 2421
+ P+ S L +P R R S +T P++ A P ++ Q ++TS
Sbjct: 1576 PELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTS 1635
Query: 2422 ERAPSPSSRMGQAPSQSLLPPAQD-QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480
++R + + P A D +P +P +DQS TP A +Q S +
Sbjct: 1636 RATRRKTNRSSVKTPKPVEPAASDLEPFTP-----TDQS------VTPEAIAQGGQSKTL 1684
Query: 2481 ATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSS 2540
++T A +P P P + P + P + K +R++ + S +
Sbjct: 1685 RSSTVRA--------MPVPTTP--EFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLA 1734
Query: 2541 SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP--KEAVREGRPPEP 2598
+ S+ S +S + G+ V+ +L +P P + + + +
Sbjct: 1735 APIDHKPCSAPLEPKSQASRNQRWGA---VRAAESLTAIPEPASPQLLETPIHASQIQKV 1791
Query: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------SSSSSPSPA 2652
PA R R + +S S S ++ S S + ++ P
Sbjct: 1792 EPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPG 1851
Query: 2653 KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ 2704
K PKP K+ E +R P SRSL + + + +P+
Sbjct: 1852 KEEDVVTPKPGKRKRDQAEEEPNRIP---------SRSLRRTKLNQESTAPK 1894
Score = 83.2 bits (204), Expect = 3e-15
Identities = 251/1218 (20%), Positives = 418/1218 (34%), Gaps = 203/1218 (16%)
Query: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS----- 771
T +R G ER+ + +R++ E+ K + + + L+ + +S
Sbjct: 820 TAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGE 879
Query: 772 -------RLSLRRSLSGSSPCPK---QKSQTPPRRSRSGSSQPKAKSRTPPRR------- 814
R SL+ + S + QK P + +P A P
Sbjct: 880 SASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPK 939
Query: 815 ---SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQS-----VT 866
R + P+ S+ Q+ SS +P P V +G P S P ++ V+
Sbjct: 940 VILERDTQRGEPEGGSQDQKGQA-SSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVS 998
Query: 867 PQRR-----SCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKA 921
P+R +C P E SR + S + PP + +P P K
Sbjct: 999 PRRHQKGLLNC--KMPPAEKASRIRAAEKVSRGDQESPDACLPP----TVPEAPAPPQKP 1052
Query: 922 IISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKP 981
+ S Q+ + SP + + T R++R E+ L SS P
Sbjct: 1053 LNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPL---------SSELEPFHP 1103
Query: 982 ETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKS 1041
+ R S ++P+P A P PS S ++ P+ S+ + ++ S+ V
Sbjct: 1104 KPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVP 1163
Query: 1042 STPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRS 1101
+ P E S+ Q TS R S V+ + P+ + Q S R +
Sbjct: 1164 TAP--ELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPT-ALELQPSTSTDRPVT 1220
Query: 1102 SSPVTELA----SRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQS 1157
S P ++ +RS ++ +P L+ S +Q +S PT +
Sbjct: 1221 SEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQ-----PVTSEPTYQA------- 1268
Query: 1158 RLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAG 1217
T K + ++ E + P + P DRP + K T RT R R+
Sbjct: 1269 ---TRGRKNRSSVKTPEPVVPTAP----ELRPSTSTDRPVTP---KPTSRT-TRSRTNMS 1317
Query: 1218 SSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER 1277
S K + +PT+ + +++ +++P ++ + S +N S E
Sbjct: 1318 S---VKTPETVVPTAPE----LQISTSTDQP----VTPKPTSRTTRSRTNMSSVKNPEST 1366
Query: 1278 PAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSG 1337
++ L S S E P +PE + + S G E
Sbjct: 1367 VPIAPELPPSTS------TEQP----------VTPEPTSRATRGRKNRSSGKTPE----- 1405
Query: 1338 PLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMS 1397
T + T E + P + +P+ Q+TR + SS +P+ V
Sbjct: 1406 ---TLVPTAPKLEPSTSTDQP----VTPEPT----SQATRGRTNRSSVKTPETV------ 1448
Query: 1398 SNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRH 1457
VP P + S+S P + P + + R R+ S + P+
Sbjct: 1449 ------------VPTAPELQPSTSTDQPVTPE--PTSQATRGRTDRSSVKTPETVVPTAP 1494
Query: 1458 SLSGSSPGMKDIPRTP----SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQ 1513
L S+ + + P +RGR S P+ + P++PEL T Q
Sbjct: 1495 ELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETV---------VPAAPELQPSTSTDQ 1545
Query: 1514 RERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDS-----SPDSKAK 1568
V + +R G+ +RS + P A + S S + P S+A
Sbjct: 1546 --------PVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRA- 1596
Query: 1569 TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628
T R S +PE + P + S P A R ++ S PK
Sbjct: 1597 --TRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVE 1654
Query: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS-RSSPEPKTKSRTPPR 1687
P A S +P S T + +S+T R + R+ P P T P
Sbjct: 1655 PAA----------SDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPV 1704
Query: 1688 RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747
SPE + +R R+A + + P H+ P + EP KS++SR +R
Sbjct: 1705 TTDQPISPEPITQPSCIKRQRAAGNPGSLAA--PIDHK--PCSAPLEP--KSQASRNQRW 1758
Query: 1748 ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807
+ + + P+P Q + + + RS + + +SR R
Sbjct: 1759 GA-----VRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKR 1813
Query: 1808 SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR 1867
S T S H + P R E S+ + + T K +P P KR R +
Sbjct: 1814 SLATM----DSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGK-EEDVVTPKPGKRKRDQ 1868
Query: 1868 ASPATHR---RSRSRTPL 1882
A +R RS RT L
Sbjct: 1869 AEEEPNRIPSRSLRRTKL 1886
Score = 82.4 bits (202), Expect = 6e-15
Identities = 222/1012 (21%), Positives = 353/1012 (34%), Gaps = 154/1012 (15%)
Query: 153 PQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRS-----ESSSPRR 207
P+R E + P + + E ++ +++K+ +D R+ ES+SP R
Sbjct: 826 PERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPER 885
Query: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSAD 267
+R+ S K + SE +K+ + P + + ++ +R PA + +
Sbjct: 886 DRE-SLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVIL-- 942
Query: 268 SASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETA 327
DT R G + ++G+ +P EPG + P T+
Sbjct: 943 ---ERDTQR----------------GEPEGGSQDQKGQASSPTPEPGVGAGDLPGP--TS 981
Query: 328 TKQPSSPYEDKDKDKKEKSATRPSP-SPERSSTG-------PEPPAPTPLLAER--HGGS 377
PS +S R SP SP R G P A AE+ G
Sbjct: 982 APVPSG----------SQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQ 1031
Query: 378 PQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSS 437
P A P P P + A P + + P S P S +PT S
Sbjct: 1032 ESPDACLP----PTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLP-SIKPTVRKTRQDGS 1086
Query: 438 PESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRS 497
E+P+ AP P + R KS TP PAT+
Sbjct: 1087 QEAPE-APLSSELEPFHPKPKIRTR--------KSSRMTPF--------PATSAAPEPHP 1129
Query: 498 RTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSA 557
T T + + + Q RSR+ +RS + P P S +T + S
Sbjct: 1130 STSTAQPVTPKPTSQATRSRT------NRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPT 1183
Query: 558 RRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617
S TRGR +SR+ + + T + + T S + A RGR
Sbjct: 1184 --------SQVTRGR-KSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKN- 1233
Query: 618 RTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR 677
R +T PV + P+ + + + P + T R+ RS +TP
Sbjct: 1234 ----RSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQA-----TRGRKNRSSVKTPEPV 1284
Query: 678 SGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTS 737
+ P+ R TP+ +RS R S +TP E +
Sbjct: 1285 VPTAPELRPST-STDRPVTPKPTSRTTRS--RTNMSSVKTP----------ETVVPTAPE 1331
Query: 738 QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS 797
+ S S P K + RSR+ S +S + + L PP S
Sbjct: 1332 LQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPEL-------------PPSTS 1378
Query: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857
P+ SR R SS P+ T + S+S+ P TP T
Sbjct: 1379 TEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPV----TPEPTSQATR 1434
Query: 858 PQANEQSV-TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ 916
+ N SV TP+ PEL+ PS + +P +T R RSS
Sbjct: 1435 GRTNRSSVKTPET----VVPTAPELQ---PSTSTDQPVTPEPTSQAT--RGRTDRSSVKT 1485
Query: 917 PKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPD 976
P+ +P ++ + + P S TSRTT R ++ S E+ + S+S D
Sbjct: 1486 PETVVPTAPELQASASTDQPVTSEPTSRTT-RGRKNRSSVKTPETVVPAAPELQPSTSTD 1544
Query: 977 TKVKPE-----TPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPG 1031
V PE T R + S +P V PS S ++ P+ S+ + ++
Sbjct: 1545 QPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRS 1604
Query: 1032 SLSLCAGVKSSTP---PGESYFGVSSLQLKGQSQTSPDHRSDTSSPE-VRQSHSE----S 1083
S+ V + P P S + +L ++ +RS +P+ V + S+ +
Sbjct: 1605 SVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFT 1664
Query: 1084 PSLQSKS-QTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPE 1134
P+ QS + + +GG+S++ T A P EF + +SPE
Sbjct: 1665 PTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTP---EFQSPVTTDQPISPE 1713
Score = 81.3 bits (199), Expect = 1e-14
Identities = 146/701 (20%), Positives = 254/701 (36%), Gaps = 106/701 (15%)
Query: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215
R + PEP P + + S+S + P + + RGR++ SS E +
Sbjct: 1231 RKNRSSVKTPEPVVPTAPELQPSTS-TDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAP 1289
Query: 216 KKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP---APKSRRAHRSTSADSASSS 272
+ S S R TPK ++ + S TP P + STS D
Sbjct: 1290 ELRPSTSTD-----RPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPV-- 1342
Query: 273 DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE--PGTTSTQRPSSPETATKQ 330
T + SR+ ++T+ +++ + E P + P +TST++P +PE T +
Sbjct: 1343 -TPKPTSRTTRSRTNMSSV----------KNPESTVPIAPELPPSTSTEQPVTPEP-TSR 1390
Query: 331 PSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTP----- 385
+ +++ K ++ +P E S++ +P P P G + + TP
Sbjct: 1391 ATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVP 1450
Query: 386 ---------LSQEPVNPPSEASPTR---DRSPPKSPEKLP------QSSSSESSPPSPQP 427
+ +PV P + TR DRS K+PE + Q+S+S P + +P
Sbjct: 1451 TAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1510
Query: 428 T------KVSRHASSSPESPKPA-----PAPGSHREISSSPTSKNRSHGRAKRDKSHSHT 476
T + +R + +PE+ PA P+ + + ++ PTS+ R + ++S T
Sbjct: 1511 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRAT---RGRTNRSSVKT 1567
Query: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRS 536
P S P + S SR SR+ + R +RS+ + +P+ +
Sbjct: 1568 PE-----SIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVK-----TPEPVVPTAP 1617
Query: 537 PQRPGWSRSRNTQRRGRSRSARR--GRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594
P S + + SR+ RR RS ++P + S +S TP
Sbjct: 1618 EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQ 1677
Query: 595 RSRTPTRRRSRSR------TPARRGRSRSRTPARRRSRTRSPVRRRSRSRS--------- 639
++ T R S R TP + + P T+ +R R+
Sbjct: 1678 GGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPI 1737
Query: 640 ----------PARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARR 689
P ++ R++ R S + P TP S + R
Sbjct: 1738 DHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRS 1797
Query: 690 GRSRSRTPRRGRSRSRSLVRR-GRSHSRTPQRRGRSGSSSERK--NKSRTSQRRSRSNSS 746
+ P+ +SR RSL H + PQR G S++ K +
Sbjct: 1798 RFTPELQPKASQSRKRSLATMDSPPHQKQPQR----GEVSQKTVIIKEEEEDTAEKPGKE 1853
Query: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787
++ + R+ ++ SR R L+ S PK
Sbjct: 1854 EDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPK 1894
Score = 77.4 bits (189), Expect = 2e-13
Identities = 209/1054 (19%), Positives = 358/1054 (33%), Gaps = 153/1054 (14%)
Query: 1726 RSPSVSSPEPAEKSRSSRRRRS--ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783
R V+ E K + R ++ A + + + + G S SP +R R + E
Sbjct: 842 RQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASP-----ERDRESLKVEIET 896
Query: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843
+ +++ Q+ + V R + + P T +RG
Sbjct: 897 SEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDT----QRGEPE 952
Query: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS- 1902
+K S +P P + P + P+ S +S R SPVS RR +
Sbjct: 953 GGSQDQKGQASSPTPEPGVGAGDLPGPTS-------APVPSGSQSGGRGSPVSPRRHQKG 1005
Query: 1903 ----RTSVTRRRSRSRASP-VSRRRSRSRT----PPVTRRRSRSRTPTTRRRSRSRTPPV 1953
+ + SR RA+ VSR S P V + + P + + PP
Sbjct: 1006 LLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPP 1065
Query: 1954 TRRRSRSRTPPVTR--RRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTS 2011
P R R+ S+ +P +P++ P R R SR +
Sbjct: 1066 LLSPLLPSIKPTVRKTRQDGSQEAP---------EAPLSSELEPFHPKPKIRTRKSSRMT 1116
Query: 2012 PVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRS 2071
P + P+ + + P+ P+ S++ +RSRT R+ S+
Sbjct: 1117 PFPATSAAPEPHPS----TSTAQPVTPKPTSQA---------TRSRTNRS-----SVKTP 1158
Query: 2072 PPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCR 2131
P + S+ + T T + R SR S + ++ PT L+
Sbjct: 1159 EPVVPTAPELQPSTSTDQPVTSEPTSQVTRGR-------KSRSSVKTPETVVPTALELQP 1211
Query: 2132 SPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLG 2191
S P+ S T + + S + P P +P + PE + +T+
Sbjct: 1212 STSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVP-----TAPELQPSTSTDQPVTS---- 1262
Query: 2192 TARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIP 2251
P+ A S V P P++ TAP ++ S P P
Sbjct: 1263 ----EPTYQATRGRKNRSSVKTPEPVVP--TAPELRPST-------------STDRPVTP 1303
Query: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSL 2311
SRT + M+ V P+A L + P +RT + +S
Sbjct: 1304 KPT----SRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS 1359
Query: 2312 TGS--GTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSA 2369
+ T P A P S+ T Q P + P S N + +T L P T+
Sbjct: 1360 VKNPESTVPIAPELPPSTSTEQ-PVTPE---PTSRATRGRKNRSSGKTPETLVP---TAP 1412
Query: 2370 RMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP----PSAPSQSRMTSERAP 2425
++ P+ S P P + GRT+ R+ +TP P+AP TS P
Sbjct: 1413 KLEPSTS---TDQPVTPEPTSQATRGRTN-----RSSVKTPETVVPTAPELQPSTSTDQP 1464
Query: 2426 SPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS 2485
QA + P + VP+A Q+ + Q ++S + TT
Sbjct: 1465 VTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA--------STDQPVTSEPTSRTTR 1516
Query: 2486 SAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS--- 2542
+ + + P VP + +P ST QP A R++ SS + S
Sbjct: 1517 GRKNRSSV-KTPETVVPAAPELQP--STSTDQPVTPEPTSRATRGRTNRSSVKTPESIVP 1573
Query: 2543 -------SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP 2595
S+S + + +S ++ + SS+ PE + P P P +P
Sbjct: 1574 IAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKT-PEPVVPTAPEPHPTTST----DQP 1628
Query: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
P R R ++ SS + ++S + + S + + + S +
Sbjct: 1629 VTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSST 1688
Query: 2656 PQALPKPASPKKPPPGERRSRSPRKPI---DSLRDSRSLS-----YSPVERRRPSPQPSP 2707
+A+P P +P+ P +PI ++ R+ +P++ + S P
Sbjct: 1689 VRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEP 1748
Query: 2708 RDQQSSSSERGSRRGQRGDSR--SPSHKRRRETP 2739
+ Q S + G+ R + P+ + ETP
Sbjct: 1749 KSQASRNQRWGAVRAAESLTAIPEPASPQLLETP 1782
Score = 73.9 bits (180), Expect = 2e-12
Identities = 248/1228 (20%), Positives = 401/1228 (32%), Gaps = 196/1228 (15%)
Query: 794 PRRSRSGSSQPKAKSRTPPR----RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP 849
P R+ G P++ T P R R + +T R + + P
Sbjct: 781 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP 840
Query: 850 PRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909
RQ +T E+ +T + + +L +R R S +S++P R
Sbjct: 841 ERQTDVTG----EEELTKGK----QDREQKQLLARDTQRQE----SDKNGESASPERDRE 888
Query: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR--RSRSVSPCS---NVESRLL 964
S KV+ S + PS+ R R +R P V +L
Sbjct: 889 SL------KVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVIL 942
Query: 965 PRYSHSGS---SSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKS 1021
R + G S D K + +P + G+ A P G G SP +
Sbjct: 943 ERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRH 1002
Query: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQS-QTSPDHRSDTSSPEV---- 1076
+ L+ PP E + + + + Q SPD + PE
Sbjct: 1003 QKGLLNC-------------KMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPP 1049
Query: 1077 -------RQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKS 1129
Q H P L S S K ++ ++ A +P+ + F P +++
Sbjct: 1050 QKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRT 1109
Query: 1130 GMSPEQSRFQSDSSSYPTVDSNSLLGQ------SRLETAESKEKMALPPQEDATASPPRQ 1183
S + F + S++ S S S+ + + P+ +P Q
Sbjct: 1110 RKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQ 1169
Query: 1184 KDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA--LPTSSQDEELMEV 1241
+ PV P S + T R+ + +PET + P++S D +
Sbjct: 1170 PSTSTDQPVTSEPTSQV-------TRGRKSRSSVKTPETVVPTALELQPSTSTDRPV--- 1219
Query: 1242 VEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ---SQASLEAVEV 1298
+ EP Q ++ ++ +S P V P + + Q S+ + +A
Sbjct: 1220 ---TSEPTSQ-----ATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRG 1271
Query: 1299 PSMASSWGGPH-FSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNG 1357
SS P P EL S + R T T SS +
Sbjct: 1272 RKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRT-----TRSRTNMSSVKTPETVV 1326
Query: 1358 PFLNQLETDPSLDMK------EQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVP 1411
P +L+ S D ++TRS + SS +P++ VP
Sbjct: 1327 PTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPEST------------------VP 1368
Query: 1412 RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR 1471
P S+S P + P + + R R S G + P+ L S+ D P
Sbjct: 1369 IAPELPPSTSTEQPVTPE--PTSRATRGRKNRSSGKTPETLVPTAPKLEPSTS--TDQPV 1424
Query: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVART 1531
T PEP + R S +PE + + ++ V + ++
Sbjct: 1425 T-----------PEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQA 1473
Query: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSP-DSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
G+ RS V P+A + S S P S+ +RT +++RS
Sbjct: 1474 TRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRS----------- 1522
Query: 1591 LSPRRSRSGSSPE--VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS--RSGSSSKGRG 1646
S +PE V P P + +PEP + A R RS ++ S
Sbjct: 1523 -------SVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIA 1575
Query: 1647 PSPEGSSSTESSPEHPPKSRTAR----RGSRSSPEPKTKSRTPPRRRSSRS---SPELTR 1699
P + S+S P SR R R S +PEP + P +S +P+LT
Sbjct: 1576 PELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTS 1635
Query: 1700 KARLSRRSRSASSSP--------ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSP 1751
+A + +RS+ +P + TP +P + K+ S R+ P
Sbjct: 1636 RATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVP 1695
Query: 1752 RT-----KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
T T+ + SP P + R R+ D S + Q SR+
Sbjct: 1696 TTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRN 1755
Query: 1807 RSRVTRRRRGGSGYHSRSPARQE-------SSRTSSRRRRGRSR-TPPTSRKRSRSRTSP 1858
+ R R S PA + +S+ GRSR TP K S+SR
Sbjct: 1756 Q-RWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSR--- 1811
Query: 1859 APWKRSRSRASPATHRRSRSR------TPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSR 1912
KRS + H++ R T +I + P + R+R +
Sbjct: 1812 ---KRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPKPGKRKRDQ 1868
Query: 1913 SRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
+ P R SR+ T+ S P
Sbjct: 1869 AEEEP---NRIPSRSLRRTKLNQESTAP 1893
Score = 32.0 bits (71), Expect = 8.6
Identities = 39/170 (22%), Positives = 57/170 (33%), Gaps = 19/170 (11%)
Query: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
SPTP P V G P PT A S S S S + + +S
Sbjct: 964 SPTPEP--GVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIR 1021
Query: 2641 SSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR 2700
++ S + P A P P+ P P P+KP++S +
Sbjct: 1022 AAEKVSRGD---QESPDACLPPTVPEAPAP-------PQKPLNSQSQKHLAPPPLLSPLL 1071
Query: 2701 PSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
PS +P+ R + S+ + P H P P+ +SSR
Sbjct: 1072 PSIKPTVRKTRQDGSQE-APEAPLSSELEPFH------PKPKIRTRKSSR 1114
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 119 bits (299), Expect = 3e-26
Identities = 203/783 (25%), Positives = 299/783 (38%), Gaps = 85/783 (10%)
Query: 154 QRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKK-KKKKKDRGRRSESSSPRRERKKS 212
QR+A+ Q + P L +S S+SP P Q ++ ++ R E + R
Sbjct: 1198 QRKAKIYTQASKSPTSTIDL--QSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYE 1255
Query: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS--TSADSAS 270
+ + ES+S+ ++ +K+ D K R T K R+ + + T+ +S S
Sbjct: 1256 FTQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPS 1315
Query: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQ 330
+ R + A +TA R P S + F + S +R +TA +
Sbjct: 1316 RELAAHLRRKRIGATQTSTASLKRQPKKPSQPK------FMQLLFQSLKRAF--QTAHRV 1367
Query: 331 PSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA-----PTPLLAERHGGSPQPLATTP 385
+S +K TRP + P+ A P+ + ++ A +
Sbjct: 1368 IASV------GRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGST 1421
Query: 386 LSQEP------VNPPSEASPTRDRSPPKSPEKLPQSSSSES-----SPPSPQPTKVSRHA 434
+ QE V S P R S P +LP+ + S+S + QP + +
Sbjct: 1422 IKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKD 1481
Query: 435 SSSPESPKPAPAPGSHREIS--SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKR 492
SSS S +E S+P ++ ++ GR T R + + T K
Sbjct: 1482 SSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHL---KDKLTHKE 1538
Query: 493 GRS----RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT 548
R RTP +P WR RS + S +RR S S QR S SR
Sbjct: 1539 HNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPS-QRSHCSPSRKN 1597
Query: 549 QRRGRSRSARRG--RSHSRSPATRGRSRSRTPARRGRSRS-RTPARRRSRS------RTP 599
RS R R+H P S S RS R P++RR S R+P
Sbjct: 1598 HSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSP 1657
Query: 600 TRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSR 659
+ R RS + RR RS S+ R S R RSP++RS R P+ R R
Sbjct: 1658 SERSHRS-SSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRG----PSER---R 1709
Query: 660 SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQ 719
+P++R R+PARRS RS S R S S S R RSH +P
Sbjct: 1710 HHSPSKRSH---RSPARRSHRSPSE---RSHHSPSERSHHSPSERRHHSPSERSHC-SPS 1762
Query: 720 RRGRSGSSSERKNKSRTSQRR----SRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSL 775
R S SER+++S + +R +S+ SP + S R R SP +++ L
Sbjct: 1763 ERSHC-SPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRR--HSPLERSRHSLLE 1819
Query: 776 RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSH 835
R S S + + RR S P KS P RS SP ++ + + H
Sbjct: 1820 RSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSP-LERSRCSPSERRGHSSSGKTCH 1878
Query: 836 SSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSS 895
S S + SG RQG TS +++ S R S E P R R+ CS S
Sbjct: 1879 SPSERSHRSPSGM--RQGR-TSERSHRSSCERTRHSPSEMRP-----GRPSGRNHCSPSE 1930
Query: 896 PPR 898
R
Sbjct: 1931 RSR 1933
Score = 116 bits (290), Expect = 3e-25
Identities = 189/742 (25%), Positives = 287/742 (38%), Gaps = 96/742 (12%)
Query: 175 RESSSSRSPTP---KQKKKKKKKDRGRRSESSSPRRERKKSSKKKK---HRSESESKKRK 228
+++S S+ P K+ +K +K R+ SP RE ++K+ ++ + S KR+
Sbjct: 1281 KKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQTSTASLKRQ 1340
Query: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288
+ P+ + + KR+ T AHR ++ D +R + A+ +
Sbjct: 1341 PKKPSQPKFMQLLFQSLKRAFQT--------AHRVIASVGRKPVDGTRPDNLWASKNYYP 1392
Query: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348
A P+S +R + A P ++ ++ T Q S ++ + A
Sbjct: 1393 KQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSA-------QQPRRAY 1445
Query: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408
P P R P+P +A + QPL T Q+ + S+ + R+
Sbjct: 1446 SFQPRPLRL---PKPTDSQSGIAFQTASVGQPLRTV---QKDSSSRSKKNFYRN------ 1493
Query: 409 PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
++SS ES S T+V P SP HR + T K +H
Sbjct: 1494 -----ETSSQESKNLSTPGTRVQARGRILPGSPVKRT---WHRHLKDKLTHKEHNHPSFY 1545
Query: 469 RDKS-------HSHTPSRRMGRSRSPATAKRG-RSRSRTPTKRGHSRSRSPQWRRSRSAQ 520
R+++ H PS R RS S + + R +P++R H S S + S S +
Sbjct: 1546 RERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC-SPSRKNHSSPSER 1604
Query: 521 RWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPAR 580
W RSP +R P+R S S R + RSH R P+ R R +P+
Sbjct: 1605 SW---RSPSQRNHCSPPERSCHSLSE------RGLHSPSQRSH-RGPSQR---RHHSPSE 1651
Query: 581 RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR-TPARRRSRTRSPVRRRS---- 635
R R+P+ R RS + R RS S+ R RS +P+ RR R+ S R
Sbjct: 1652 RSH---RSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSER 1708
Query: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
R SP++RS RS PARR R+P+ R +P+ RS S S RS
Sbjct: 1709 RHHSPSKRSHRS----PARRSH---RSPSERSH---HSPSERSHHSPSERRHHSPSERSH 1758
Query: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRIS 755
RS RR RS S S +S S R +S E + +
Sbjct: 1759 CSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLL 1818
Query: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQ-TPPRRSRSGSSQPKAKSRTPPRR 814
R RS S RS S RR +S S P +KS +P RSR S+ RR
Sbjct: 1819 ERSHRSPSERRSHRSFERSHRR-ISERSHSPSEKSHLSPLERSRCSPSE---------RR 1868
Query: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
SSS + +PS +SH S S + ++ + S + + + P R S
Sbjct: 1869 GHSSSG----KTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRN 1924
Query: 875 SSPDPELKSRTPSRHSCSGSSP 896
E R+P + S P
Sbjct: 1925 HCSPSERSRRSPLKEGLKYSFP 1946
Score = 97.8 bits (242), Expect = 1e-19
Identities = 164/574 (28%), Positives = 215/574 (37%), Gaps = 86/574 (14%)
Query: 1510 LTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKT 1569
LTP E + TV Q R+ S Q +P P+ A
Sbjct: 1415 LTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQP---RPLRLPKPTDSQSGIAFQTASV 1471
Query: 1570 RTPLR--QRSRSGSSPEVDSKSRLSPRRSRSGSSP--EVKDKPRAAP---------RAQS 1616
PLR Q+ S S + ++ S + S++ S+P V+ + R P R
Sbjct: 1472 GQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLK 1531
Query: 1617 GSDSSPEPKAPA------PRALPRRSRSGSSSKG-RGPSPEGSSSTESSPEHPPKSRTAR 1669
+ E P+ PR R+R S + R PS S+ H P R+
Sbjct: 1532 DKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC 1591
Query: 1670 RGSRSS-PEPKTKSRTPPRRRSSRSSPE-----LTRKARLSRRSRSASSSPETRSRTPP- 1722
SR + P +S P +R+ S PE L+ + S RS + R +P
Sbjct: 1592 SPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSE 1651
Query: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR-SPSPKPRGLQRSRSRSRREK 1781
R RSPS E + +S S RR RS S + S R SPS + R RS S+R
Sbjct: 1652 RSHRSPS----ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSER-----RHRSPSQRSH 1702
Query: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841
+ RR S S +S RS R R S SP+ + S RR
Sbjct: 1703 RGPSERRHHSPSKRS---------HRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP 1753
Query: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSR 1901
S RS SP+ RS SP+ R R+P R S S S S R
Sbjct: 1754 S---------ERSHCSPS----ERSHCSPSERRH---RSPSERRHHSPSEKSHHS-PSER 1796
Query: 1902 SRTSVTRRRSRSRASPVSRRR----SRSRTPPVTRRRSRSRTPTTRRRS-RSRTPPVTRR 1956
S S + RR R SP+ R R RS P RR RS + RR S RS +P
Sbjct: 1797 SHHSPSERR---RHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSP----- 1848
Query: 1957 RSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRR 2016
+S P+ RSR SP RR S RS SP R+ R+
Sbjct: 1849 SEKSHLSPL----ERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSS 1904
Query: 2017 RSRSRTPPAIRR--RSRSRTPLLPRKRSRSRSPL 2048
R+R P+ R R R P +RSR RSPL
Sbjct: 1905 CERTRHSPSEMRPGRPSGRNHCSPSERSR-RSPL 1937
Score = 97.8 bits (242), Expect = 1e-19
Identities = 138/508 (27%), Positives = 197/508 (38%), Gaps = 99/508 (19%)
Query: 194 KDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP 253
KD+ E + P R+++ + R+ R HRSP+ +S+R S +++ +
Sbjct: 1531 KDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSH 1590
Query: 254 APKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG-RSPSPASGRRGEGDAPFSE 312
SR+ H S S + + S + R+ H+ + G SPS S R
Sbjct: 1591 CSPSRKNHSSPS-ERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRG--------- 1640
Query: 313 PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE 372
S +R SP + + SP E + E+ PS +RS GP +E
Sbjct: 1641 ---PSQRRHHSPSERSHR--SPSERSHRSSSERRHRSPS---QRSHRGP---------SE 1683
Query: 373 RHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR 432
R SP S R RSP + + P R
Sbjct: 1684 RSHCSP-------------------SERRHRSPSQRSHRGPSER---------------R 1709
Query: 433 HASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKR 492
H S S S + +PA SHR S RSH + ++SH H+PS R R SP+
Sbjct: 1710 HHSPSKRSHR-SPARRSHRSPSE------RSH-HSPSERSH-HSPSER--RHHSPSERSH 1758
Query: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQR--PGWSRSRNT-- 548
R+ R RSP RR S +R S S +R RSR++
Sbjct: 1759 CSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLL 1818
Query: 549 QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR----SRSR-TPARRRSRS------R 597
+R RS S RR R RS +P+ + RSR +P+ RR S
Sbjct: 1819 ERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCH 1878
Query: 598 TPTRRRSRSRTPARRGRSRSRTPARRRSRTR-SPVRRRSRSRSPARRSGRSRSRTPARRG 656
+P+ R RS + R+GR+ R+ RTR SP R P R SGR+ +P+ R
Sbjct: 1879 SPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMR-----PGRPSGRNHC-SPSERS 1932
Query: 657 RSRSRTPARRGRSRSRTPARRSGRSRSR 684
R R+P + G S P R S SR
Sbjct: 1933 R---RSPLKEGLKYS-FPGERPSHSLSR 1956
Score = 95.1 bits (235), Expect = 8e-19
Identities = 147/493 (29%), Positives = 186/493 (37%), Gaps = 110/493 (22%)
Query: 1428 KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487
++ PR PS R+R +P R+ +PS S S ++ +PS+ RS C S +
Sbjct: 1546 RERTPRGPSERTRH--NPSWRNHR-SPSERSQRSS---LERRHHSPSQ-RSHCSPSRKNH 1598
Query: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRE-RSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
+ P RS SP N C P+R S SE + + QRS G SQ
Sbjct: 1599 SSPS-----ERSWRSPSQRNHCSPPERSCHSLSERGLHSPS-------QRSHRGPSQRRH 1646
Query: 1547 VKPSA----SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP 1602
PS SP ERS SS + + R+P QRS G S RS SP
Sbjct: 1647 HSPSERSHRSPSERSHRSSS---ERRHRSP-SQRSHRGPS-------------ERSHCSP 1689
Query: 1603 EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662
RR RS S RGPS S
Sbjct: 1690 S-----------------------------ERRHRSPSQRSHRGPSERRHHSPSKRSHRS 1720
Query: 1663 PKSRTARRGS-RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP 1721
P R+ R S RS P +S P R S E ++ S RS S E R R+P
Sbjct: 1721 PARRSHRSPSERSHHSPSERSHHSPSERRHHSPSE---RSHCSPSERSHCSPSERRHRSP 1777
Query: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781
R P+EKS S RS SP + RR SP L+RSR S E+
Sbjct: 1778 SERRHH------SPSEKSHHSPSERSHHSP----SERRRHSP------LERSR-HSLLER 1820
Query: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841
+ + RS R RS R++ R S SP E SR S RRG
Sbjct: 1821 SHRSPSERRS--------HRSFERSHRRISERSHSPSEKSHLSPL--ERSRCSPSERRGH 1870
Query: 1842 SRTPPTSRKRS-RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRS 1900
S + T S RS SP+ ++ R+ S +HR S RT R S S P R
Sbjct: 1871 SSSGKTCHSPSERSHRSPSGMRQGRT--SERSHRSSCERT-----RHSPSEMRP-GRPSG 1922
Query: 1901 RSRTSVTRRRSRS 1913
R+ S + R RS
Sbjct: 1923 RNHCSPSERSRRS 1935
Score = 92.4 bits (228), Expect = 5e-18
Identities = 197/819 (24%), Positives = 298/819 (36%), Gaps = 137/819 (16%)
Query: 386 LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAP 445
+ + P++P + ++ KSP S S P+P + R S P+ +
Sbjct: 1189 IRRSPISPSQRKAKIYTQAS-KSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTK 1247
Query: 446 --APGSHR--EISSSPTSKNRSHGRAKRDK------SHSHTPSRRMGRSRSPATAKRGRS 495
APG + ++ + P S + S KR K S S P +R+ ++ ++ +
Sbjct: 1248 TRAPGHYEFTQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRI--TKRLRKHRKFYT 1305
Query: 496 RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW--------SRSRN 547
SRT T SR + RR R + S +R+ + P +P + R+
Sbjct: 1306 NSRT-TIESPSRELAAHLRRKRIGATQTSTASLKRQ--PKKPSQPKFMQLLFQSLKRAFQ 1362
Query: 548 TQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSR----TPTRR- 602
T R + R+ +R P S++ P + R + +R + TP
Sbjct: 1363 TAHRVIASVGRKPVDGTR-PDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGST 1421
Query: 603 ------------RSRSRTPARRGRSRSRTPARRRSRTRS-------------PVRRRSRS 637
+ RS RR S P R T S P+R +
Sbjct: 1422 IKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKD 1481
Query: 638 RSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR----TPARRSGRSRSRTPARRGRS- 692
S + R+ T ++ ++ S TP R ++R R +P +R+ +
Sbjct: 1482 SSSRSKKNFYRNETSSQESKNLS-TPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHN 1540
Query: 693 -----RSRTPR--RGRSRSRSLVRRGRSHSRTPQRRG----------RSGSSSERKNKSR 735
R RTPR R+R R RS S QR RS S RKN S
Sbjct: 1541 HPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSS 1600
Query: 736 TSQRRSRSNSS------PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK 789
S+R RS S PE +S R L SP ++ S RR S S ++
Sbjct: 1601 PSERSWRSPSQRNHCSPPERSCHSLSER---GLHSPSQRSHRGPSQRRHHSPS----ERS 1653
Query: 790 SQTPPRRSRSGSSQPKAKS------RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH-- 841
++P RS SS+ + +S R P RS S P +++ ++PS++SH S
Sbjct: 1654 HRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS---PSERRHRSPSQRSHRGPSERRH 1710
Query: 842 --PKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS-CSGSSPPR 898
P +S P + S SP +P RS S E + +PS S CS S
Sbjct: 1711 HSPSKRSHRSPARRSHRSPSERSHH-SPSERSHHSPS---ERRHHSPSERSHCSPSERSH 1766
Query: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
S +SPS P K+ SP +RSH SPS R R +P S
Sbjct: 1767 CSPSERRHRSPSERRHHSPSEKSHHSPSERSH---HSPSERR---RHSPLERSRHSLLER 1820
Query: 959 VESRLLPRYSHSGSSSPDTKV--KPETPPRQSHSGSISPYPKVKAQTPP--GPSLSGSKS 1014
R SH ++ + +P +SH +SP + + G S SG
Sbjct: 1821 SHRSPSERRSHRSFERSHRRISERSHSPSEKSH---LSPLERSRCSPSERRGHSSSGKTC 1877
Query: 1015 PCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSS- 1073
P E+S S G S + S S + + G++ SP RS S
Sbjct: 1878 HSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPL 1937
Query: 1074 --------PEVRQSHSES------PSLQSKSQTSPKGGR 1098
P R SHS S +L + +PK G+
Sbjct: 1938 KEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
Score = 92.4 bits (228), Expect = 5e-18
Identities = 155/548 (28%), Positives = 207/548 (37%), Gaps = 63/548 (11%)
Query: 1476 GRSECDSSPEPK-ALPQTPRPRSRSPSSPELNNKCLTPQRERSG---SESSVDQ--KTVA 1529
G +C S+ +P+ A PRP R P P +SG +SV Q +TV
Sbjct: 1431 GTVQCRSAQQPRRAYSFQPRPL-RLPK----------PTDSQSGIAFQTASVGQPLRTV- 1478
Query: 1530 RTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589
Q+ S S++ + S QE S++ S+P ++ + R + S + K
Sbjct: 1479 -----QKDSSSRSKKNFYRNETSSQE-SKNLSTPGTRVQARGRILPGSPVKRTWHRHLKD 1532
Query: 1590 RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA----LPRRSRSGSSSKGR 1645
+L+ + S + PR + S ++P+ R+ L RR S S
Sbjct: 1533 KLTHKEHNHPSFYRERT-PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC 1591
Query: 1646 GPSPEGSSS-TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLS 1704
PS + SS +E S P + RS + P +RS R P R S
Sbjct: 1592 SPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRG-PSQRRHHSPS 1650
Query: 1705 RRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR---SSRRRRSASSPRTKTTSRRGR 1761
RS + S RS + RHR S P+E+S S RR RS S R R
Sbjct: 1651 ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPS-------QRSHR 1703
Query: 1762 SPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYH 1821
PS + R S S+R RR RS S +S +RS S RR S
Sbjct: 1704 GPSER-----RHHSPSKRSHRSPARRSHRSPSERSHHSPSERSH-HSPSERRHHSPSERS 1757
Query: 1822 SRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881
SP+ + S RR R S S +S SP+ RS SP+ RR +P
Sbjct: 1758 HCSPSERSHCSPSERRHRSPSERRHHS-PSEKSHHSPS----ERSHHSPSERRR---HSP 1809
Query: 1882 LISRRRS---RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR----SRSRTPPVTRRR 1934
L R S RS SP RR RS RR S SP + RSR P RR
Sbjct: 1810 LERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRG 1869
Query: 1935 SRSRTPTTRRRS-RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRR 1993
S T S RS P R+ R+ R+R SP R R
Sbjct: 1870 HSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPS 1929
Query: 1994 SRSRTSPV 2001
RSR SP+
Sbjct: 1930 ERSRRSPL 1937
Score = 86.7 bits (213), Expect = 3e-16
Identities = 125/446 (28%), Positives = 178/446 (39%), Gaps = 64/446 (14%)
Query: 167 PPKPYSLVRESSSSRSP-TPKQKKKKKKKDRGRRSESS----SPRRERKKSSKKKKHRSE 221
P P R + S R+ +P ++ ++ +R S S SP R+ S ++ RS
Sbjct: 1550 PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSP 1609
Query: 222 SESKKRKHRSPTPKSKRKSKDK-KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR 280
S+ R H SP +S ++ S+ + P RR H + S S+ S R
Sbjct: 1610 SQ---RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSH---R 1663
Query: 281 SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDK 340
S++ + H RSPS S RG + P + PS + + + PS
Sbjct: 1664 SSSERRH------RSPSQRS-HRGPSERSHCSPSERRHRSPS--QRSHRGPSERRHHSPS 1714
Query: 341 DKKEKSATR---PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEA 397
+ +S R SPS ERS P + RH + +P + +P
Sbjct: 1715 KRSHRSPARRSHRSPS-ERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSP---- 1769
Query: 398 SPTRDRSPPK----SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453
S R RSP + SP + S SE S SP R S E + + SHR
Sbjct: 1770 SERRHRSPSERRHHSPSEKSHHSPSERSHHSPS----ERRRHSPLERSRHSLLERSHRSP 1825
Query: 454 SS--SPTSKNRSHGRAKRDKSHSHTPSRR-----MGRSRSPATAKRGRSRS----RTPTK 502
S S S RSH +R SH+PS + + RSR + +RG S S +P++
Sbjct: 1826 SERRSHRSFERSH---RRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSE 1882
Query: 503 RGHSRSRSPQ-WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGR 561
R H RSP R+ R+++R RS S +R S S RPG RN + R R
Sbjct: 1883 RSH---RSPSGMRQGRTSERSHRS-SCERTRHSPSEMRPGRPSGRN-----HCSPSERSR 1933
Query: 562 SHSRSPATRGRSRSRTPARRGRSRSR 587
RSP G S R S SR
Sbjct: 1934 ---RSPLKEGLKYSFPGERPSHSLSR 1956
Score = 82.0 bits (201), Expect = 7e-15
Identities = 208/845 (24%), Positives = 308/845 (36%), Gaps = 135/845 (15%)
Query: 1392 EKAGMSSNQSISSPVLDAVPRTPSRERS--------SSASSPEMKDGLPRTPSR-----R 1438
+++ +S + PV+ P +PS+ ++ S S+ +++ G ++P+ R
Sbjct: 1174 KRSQISKYRERDRPVIRRSPISPSQRKAKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIR 1233
Query: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSR 1498
S P L + + T +PG + + + S+ +S+ K + S
Sbjct: 1234 RGQRSRPDLVEKTKT--------RAPGHYEFTQVHNLPESDSESTQNEKRAKVRTKKTSD 1285
Query: 1499 SPSSPELNNKCLTPQRE-RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERS 1557
S + K L R+ + S ++++ + +R R G++Q P++ S
Sbjct: 1286 SKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQTSTASLKRQPKKPS 1345
Query: 1558 ESDSSP----DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
+ K +T R + G P VD +R + P+ + P
Sbjct: 1346 QPKFMQLLFQSLKRAFQTAHRVIASVGRKP-VDG-TRPDNLWASKNYYPKQNARDYCLPS 1403
Query: 1614 AQSGSDSSPEPKAPAPRALPRRSR--SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG 1671
+ S + PA + + G+ P + S + P PK ++ G
Sbjct: 1404 SIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSG 1463
Query: 1672 ----SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS 1727
+ S +P RT + SSRS R S+ S++ S+ P TR + R R
Sbjct: 1464 IAFQTASVGQPL---RTVQKDSSSRSKKNFYRNETSSQESKNLST-PGTRVQA--RGRIL 1517
Query: 1728 PSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
P S +R + K T + PS R R+ R + TR
Sbjct: 1518 PG-----------SPVKRTWHRHLKDKLTHKEHNHPS-------FYRERTPRGPSERTRH 1559
Query: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR---- 1843
+ +S S R QRS + RR S SP+R+ S S R R S+
Sbjct: 1560 NPSWRNHRSPSERSQRSS----LERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHC 1615
Query: 1844 TPPTSRKRSRS-RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS 1902
+PP S S R +P +RS S H R+ RS R+S R RS S
Sbjct: 1616 SPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSH-RSSSERRHRSPS 1674
Query: 1903 RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
+ S RS SP S RR RS + R S R + +RS R+P RS S
Sbjct: 1675 QRSHRGPSERSHCSP-SERRHRSPSQRSHRGPSERRHHSPSKRSH-RSPARRSHRSPSE- 1731
Query: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRR----SRSRTSPVTRRRSRSRTSPVTRRRS 2018
RS SP RS SP RR RS SP RS SP RR
Sbjct: 1732 --------RSHHSP----SERSHHSPSERRHHSPSERSHCSP----SERSHCSPSERRH- 1774
Query: 2019 RSRTPPAIRRRSRS-RTPLLPRKRSRSRSPLAIRRRS------------RSRTPRTARGK 2065
R+P R S S ++ P +RS SP RR S R+P R
Sbjct: 1775 --RSPSERRHHSPSEKSHHSPSERSH-HSPSERRRHSPLERSRHSLLERSHRSPSERRSH 1831
Query: 2066 RSLTRSPPAIRRRSASGSS--------------------SDRSRSATPPATRNH---SGS 2102
RS RS I RS S S S ++ P+ R+H SG
Sbjct: 1832 RSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGM 1891
Query: 2103 RTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGP 2162
R + S R SC R SP+ + R G S R+ S L++ G PG
Sbjct: 1892 RQGRTSERSHRSSC-ERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKE--GLKYSFPGE 1948
Query: 2163 RIPDH 2167
R P H
Sbjct: 1949 R-PSH 1952
Score = 79.3 bits (194), Expect = 5e-14
Identities = 124/435 (28%), Positives = 163/435 (37%), Gaps = 90/435 (20%)
Query: 1412 RTPSRERSSSASSPEMKDGLPR-----TPSRRS------RSGSSPGLRDGSGTPSRHSLS 1460
R+PS S SS E + P +PSR++ RS SP R+ P R S
Sbjct: 1567 RSPSER--SQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHS 1624
Query: 1461 GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRS-RSPSSPELNNKCLTPQRERSGS 1519
S G+ + RG S+ +P RS RSPS E +++ + +R RS S
Sbjct: 1625 LSERGLHSPSQRSHRGPSQ--------RRHHSPSERSHRSPS--ERSHRSSSERRHRSPS 1674
Query: 1520 ESSVDQKTVARTPLGQRSRSGSSQELDVKPSA----SPQERSESDSSP-----DSKAKTR 1570
QRS G S+ PS SP +RS S SK R
Sbjct: 1675 ---------------QRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHR 1719
Query: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR 1630
+P R+ RS S +S SP RS SP + + R S SP ++
Sbjct: 1720 SPARRSHRSPSE-----RSHHSPSE-RSHHSPSERRHHSPSER----SHCSPSERSHCSP 1769
Query: 1631 ALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS-------R 1683
+ RR RS S + PS + S H P R R SP +++ R
Sbjct: 1770 S-ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERR-----RHSPLERSRHSLLERSHR 1823
Query: 1684 TPPRRRSSRSSPELTRKARLSRRSRSASS----SPETRSRTPPRHRRSPSVS-------- 1731
+P RRS RS R R+S RS S S SP RSR P RR S S
Sbjct: 1824 SPSERRSHRSFERSHR--RISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPS 1881
Query: 1732 -----SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTR 1786
SP + R+S R +S RT+ + R P R RSRR +
Sbjct: 1882 ERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGL 1941
Query: 1787 RRDRSGSSQSTSRRR 1801
+ G S S R
Sbjct: 1942 KYSFPGERPSHSLSR 1956
Score = 74.3 bits (181), Expect = 2e-12
Identities = 108/431 (25%), Positives = 160/431 (37%), Gaps = 89/431 (20%)
Query: 153 PQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS 212
P+R + P S R S R +P ++ + +R RS SS RR R S
Sbjct: 1618 PERSCHSLSERGLHSPSQRSH-RGPSQRRHHSPSERSHRSPSERSHRS--SSERRHRSPS 1674
Query: 213 SKKKK---HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
+ + RS +R+HRSP+ +S R +++ + +RR+HRS S S
Sbjct: 1675 QRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERS- 1733
Query: 270 SSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATK 329
S + ++H + R SP SE S S + +
Sbjct: 1734 ---------HHSPSERSHHSPSERRHHSP------------SERSHCSPSERSHCSPSER 1772
Query: 330 QPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
+ SP E + EKS PS ERS P +ER SP + L +
Sbjct: 1773 RHRSPSERRHHSPSEKSHHSPS---ERSHHSP---------SERRRHSPLERSRHSLLER 1820
Query: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
PSE RS +S ++ + S S S P + SR SP
Sbjct: 1821 SHRSPSER--RSHRSFERSHRRISERSHSPSEKSHLSPLERSR---CSP----------- 1864
Query: 450 HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSR 509
S+ R H + + H+PS R RSP+ ++GR+ R+ RS
Sbjct: 1865 ---------SERRGHSSSGKT---CHSPSER--SHRSPSGMRQGRTSERS------HRSS 1904
Query: 510 SPQWRRSRSAQRWGRSR-----SPQRRGRSRSPQR-------PGWSRSRNTQRRGRSRSA 557
+ R S S R GR SP R R RSP + PG S + R ++++
Sbjct: 1905 CERTRHSPSEMRPGRPSGRNHCSPSERSR-RSPLKEGLKYSFPGERPSHSLSRDFKNQTT 1963
Query: 558 RRGRSHSRSPA 568
G +H A
Sbjct: 1964 LLGTTHKNPKA 1974
Score = 68.6 bits (166), Expect = 8e-11
Identities = 70/236 (29%), Positives = 88/236 (37%), Gaps = 10/236 (4%)
Query: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
G PS + P++ R S S S S S S SSS S G S
Sbjct: 1629 GLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS 1688
Query: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633
+ +R SP+ E R +P+KR RS + S S S S S S S S S
Sbjct: 1689 PSERRHRSPSQRSHRGPSERR--HHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPS 1746
Query: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
S S S S P ++ P+ + P ERR SP + RS +
Sbjct: 1747 ERRHHSPSERSHCS------PSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERS-HH 1799
Query: 2694 SPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRE-TPSPRPMRHRS 2748
SP ERRR SP R S R + S SH+R E + SP H S
Sbjct: 1800 SPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLS 1855
Score = 64.7 bits (156), Expect = 1e-09
Identities = 212/932 (22%), Positives = 322/932 (34%), Gaps = 197/932 (21%)
Query: 607 RTPARRGRSRSRTPARRRSRTRSPVRR-RSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
RTP G R R R RS + + R R R RRS S S+ A+ S++P
Sbjct: 1154 RTPEGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRKAKIYTQASKSP-- 1211
Query: 666 RGRSRSRTPARRSGRSRSRTPA----RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRR 721
+ T +SG S+S P RRG+ RSR ++++R+ H Q
Sbjct: 1212 -----TSTIDLQSGPSQSPAPVQVYIRRGQ-RSRPDLVEKTKTRA-----PGHYEFTQVH 1260
Query: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG 781
S SE + ++ R++ S + RI+ R R K + R ++
Sbjct: 1261 NLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRL-------RKHRKFYTNSRTTIES 1313
Query: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKS--RTPPRRSRSSSSPPPKQKSKTPSRQSHSS-S 838
P ++ RR R G++Q S R P + S+ Q K + +H +
Sbjct: 1314 ----PSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIA 1369
Query: 839 SPHPKVKSGTPPRQGSITS---PQANEQ------SVTPQRRSCFESSPDPELKSRTPSRH 889
S K GT P + P+ N + S+ +RS + +P T +
Sbjct: 1370 SVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTP----AGSTIKQE 1425
Query: 890 SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949
+ +S+ PR++ S P K S + +S P R + + R
Sbjct: 1426 DILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSR 1485
Query: 950 SRSV---SPCSNVESRLLPRYSHSGSSSPDTKVK------PETPPRQSHSGSISP----- 995
S+ + S+ ES+ L S+P T+V+ P +P +++ +
Sbjct: 1486 SKKNFYRNETSSQESKNL--------STPGTRVQARGRILPGSPVKRTWHRHLKDKLTHK 1537
Query: 996 ---YPKV-KAQTPPGPSLSGSKSPC------PQEKSKDSLVQS---CPGSLSLCA-GVKS 1041
+P + +TP GPS +P P E+S+ S ++ P S C+ K+
Sbjct: 1538 EHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKN 1597
Query: 1042 STPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP-SLQSKSQTSPKGGRSR 1100
+ P E +S SP R+ S PE R HS S L S SQ S +G R
Sbjct: 1598 HSSPSE------------RSWRSPSQRNHCSPPE-RSCHSLSERGLHSPSQRSHRGPSQR 1644
Query: 1101 SSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLE 1160
+E + RSP +R S+S + SP Q + S R
Sbjct: 1645 RHHSPSERSHRSP--SERSHRSSSE--RRHRSPSQRSHRGPS--------------ERSH 1686
Query: 1161 TAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSP 1220
+ S+ + P Q P ++ SP K + R+P R + SP
Sbjct: 1687 CSPSERRHRSPSQRSHRG--PSERRHHSP------------SKRSHRSPARR---SHRSP 1729
Query: 1221 ETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAV 1280
+ +S E+S + H SE S S E R
Sbjct: 1730 SERSHHSP-------------SERSHHSPSERRHHSPSERSHCSPSERSHCSPSERR--- 1773
Query: 1281 SLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLG 1340
+S S+ H SP K S+ E S SP E R PL
Sbjct: 1774 ----HRSPSERR----------------HHSPSEK--SHHSPSERSHHSPSERRRHSPL- 1810
Query: 1341 TEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQ 1400
E L + PS +S S SE S EK+ +S
Sbjct: 1811 ------------ERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSP-- 1856
Query: 1401 SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLS 1460
L+ +PS R S+S +PS RS S G+R G + H S
Sbjct: 1857 ------LERSRCSPSERRGHSSSGKTC-----HSPSERSHRSPS-GMRQGRTSERSHRSS 1904
Query: 1461 GSSPGMKDIPRTPSR--GRSECDSSPEPKALP 1490
P R GR+ C S + P
Sbjct: 1905 CERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936
Score = 59.3 bits (142), Expect = 5e-08
Identities = 83/291 (28%), Positives = 111/291 (38%), Gaps = 45/291 (15%)
Query: 2494 LSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE-RRSSSSSSSSSSSSSSSSSSSSS 2552
L +P P S + AS G QP + ++ SSS S + + +SS S
Sbjct: 1452 LRLPKPTDSQSGIAFQTASVG----------QPLRTVQKDSSSRSKKNFYRNETSSQESK 1501
Query: 2553 SSSSGSSSSDSEGSSLPVQP-----------EVALKRVPSP------TP-APKEAVREGR 2594
+ S+ + + G LP P ++ K P TP P E R
Sbjct: 1502 NLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNP 1561
Query: 2595 P--PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
+P++R +RSS S S S S S + SS S S S S + S P +
Sbjct: 1562 SWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERS 1621
Query: 2653 --KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ------ 2704
+ L P+ P +RR SP + RS S ERR SP
Sbjct: 1622 CHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERS-HRSSSERRHRSPSQRSHRG 1680
Query: 2705 PSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR---HRSSRSP 2752
PS R S SER R + R PS +RR +PS R R RS RSP
Sbjct: 1681 PSER-SHCSPSERRHRSPSQRSHRGPS-ERRHHSPSKRSHRSPARRSHRSP 1729
Score = 57.4 bits (137), Expect = 2e-07
Identities = 85/303 (28%), Positives = 109/303 (35%), Gaps = 44/303 (14%)
Query: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ-SLLPPAQDQPRSPV------PSAFSDQ 2458
RS PS S + R SPS R + PS+ S P++ + RSP PS
Sbjct: 1652 RSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHH 1711
Query: 2459 SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQP 2518
S + +P S S + S H+ P+ HS P+ P
Sbjct: 1712 SPSKRSHRSPARRSHRSPSERSHHSPSERSHHS-----PSERRHHS-----PSERSHCSP 1761
Query: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
S + P+ ERR S S S S S S S S S S S L L+R
Sbjct: 1762 SERSHCSPS-ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLER 1820
Query: 2579 V---PSPTPAPKEAVREGR--------PPEPT---PAKRKRRSSSSSSSSSSSSSSSSSS 2624
PS + + R R P E + P +R R S S SSS + S
Sbjct: 1821 SHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSP 1880
Query: 2625 SSSSSSSSS-------SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS 2677
S S S S S S SS + SPS +PG +P+ P ER RS
Sbjct: 1881 SERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPG-----RPSGRNHCSPSERSRRS 1935
Query: 2678 PRK 2680
P K
Sbjct: 1936 PLK 1938
Score = 55.1 bits (131), Expect = 1e-06
Identities = 111/465 (23%), Positives = 179/465 (38%), Gaps = 55/465 (11%)
Query: 1669 RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSP 1728
R G RS K + R P R S SP + ++ S+S +S+ + +S P
Sbjct: 1171 RIGKRSQIS-KYRERDRPVIRRSPISPSQRKAKIYTQASKSPTSTIDLQS--------GP 1221
Query: 1729 SVSSPEPAEKS-RSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
S SP P + R +R R +TKT + G + L S S S + + R R
Sbjct: 1222 S-QSPAPVQVYIRRGQRSRPDLVEKTKTRAP-GHYEFTQVHNLPESDSESTQNEKRAKVR 1279
Query: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPT 1847
++ S+ +R + R R R+ S SP+R+ ++ R+R G ++T
Sbjct: 1280 TKKTSDSKYPMKRITK---RLRKHRKFYTNSRTTIESPSRELAAHLR-RKRIGATQTSTA 1335
Query: 1848 SRKRSRSRTSPAPWKR----SRSRASPATHR--RSRSRTPLISRRRSRSRTSPVSRRRSR 1901
S KR + S + + S RA HR S R P+ R S +
Sbjct: 1336 SLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASKNYYPKQN 1395
Query: 1902 SR-----TSVTR-RRSRSRASPVSRR------------RSRSRTPPVTRRRSRSRTPTTR 1943
+R +S+ R +RS + +P + RS P RR+ S P
Sbjct: 1396 ARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQP---RRAYSFQP--- 1449
Query: 1944 RRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTR 2003
R R P ++ +T V + + +R + + + + S++ ++P TR
Sbjct: 1450 RPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTR 1509
Query: 2004 RRSRSRT---SPVTRRRSRSRTPPAIRRRS------RSRTPLLPRKRSRSRSPLAIRRRS 2054
++R R SPV R R + R RTP P +R+R R
Sbjct: 1510 VQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSP 1569
Query: 2055 RSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
R+ R++ +R + S + S SS RS P+ RNH
Sbjct: 1570 SERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNH 1614
Score = 54.3 bits (129), Expect = 2e-06
Identities = 75/259 (28%), Positives = 95/259 (36%), Gaps = 30/259 (11%)
Query: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ----P 2572
Q S+L + +RS S S + SS S S S S + S + SL + P
Sbjct: 1574 QRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSP 1633
Query: 2573 EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632
R PS + R R +P++R RSSS S S S S S S
Sbjct: 1634 SQRSHRGPSQRRHHSPSERSHR----SPSERSHRSSSERRHRSPSQRSHRGPSERSHCSP 1689
Query: 2633 SSSSSSSSSSSS----------SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPI 2682
S S S S S S S P ++ P+ P ER SP +
Sbjct: 1690 SERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR 1749
Query: 2683 DSLRDSRSLSYSPVERRRPSP------QPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
RS SP ER SP PS R + S SE+ SPS +RRR
Sbjct: 1750 HHSPSERS-HCSPSERSHCSPSERRHRSPSER-RHHSPSEKSHHSPSERSHHSPS-ERRR 1806
Query: 2737 ETP---SPRPMRHRSSRSP 2752
+P S + RS RSP
Sbjct: 1807 HSPLERSRHSLLERSHRSP 1825
Score = 46.2 bits (108), Expect = 4e-04
Identities = 102/444 (22%), Positives = 156/444 (35%), Gaps = 84/444 (18%)
Query: 2357 TAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP------ 2410
T A+ +P S + P+ S A P+ Y R R+ P L+++ ++R P
Sbjct: 1205 TQASKSPTSTIDLQSGPSQSPA-------PVQVYIRRGQRSRPDLVEKTKTRAPGHYEFT 1257
Query: 2411 -----PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ 2465
P + S+S +RA + + S S P + R F SR I
Sbjct: 1258 QVHNLPESDSESTQNEKRAKVRTKKT----SDSKYPMKRITKRLRKHRKFYTNSRTTIES 1313
Query: 2466 TTP--VAGSQSLSSGAVATTTSSAGDHNGMLSVP------------APGVPH---SDVGE 2508
+ A + GA T+T+S S P A H + VG
Sbjct: 1314 PSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGR 1373
Query: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE-GSS 2567
P G + + A+ ++ + SS S+ + + S D G +
Sbjct: 1374 KPVD-GTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGT 1432
Query: 2568 LPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS 2627
+ + +R S P P R P+PT S S + ++S +
Sbjct: 1433 VQCRSAQQPRRAYSFQPRPL------RLPKPT-------DSQSGIAFQTASVGQPLRTVQ 1479
Query: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK----PASPKKPP-------------- 2669
SSS S + + +SS S + + PG + + P SP K
Sbjct: 1480 KDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEH 1539
Query: 2670 --PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDS 2727
P R R+PR P + R ++P R S PS R Q+SS R QR
Sbjct: 1540 NHPSFYRERTPRGPSERTR------HNPSWRNHRS--PSERSQRSSLERRHHSPSQRSHC 1591
Query: 2728 RSPSHKRRRETPSPRPMRHRSSRS 2751
SPS K +PS R R S R+
Sbjct: 1592 -SPSRK-NHSSPSERSWRSPSQRN 1613
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.118 0.324
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 132,923,574
Number of Sequences: 37866
Number of extensions: 8877463
Number of successful extensions: 278723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1879
Number of HSP's successfully gapped in prelim test: 3719
Number of HSP's that attempted gapping in prelim test: 50580
Number of HSP's gapped (non-prelim): 92741
length of query: 2752
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2632
effective length of database: 13,703,598
effective search space: 36067869936
effective search space used: 36067869936
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.