Search of human proteins with 239751418

Search of human proteins with 239751418

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo
sapiens]
         (528 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo ...  1084   0.0  
gi|40538728 pleckstrin homology domain containing, family M (wit...  1033   0.0  
gi|239756837 PREDICTED: similar to pleckstrin homology domain co...   877   0.0  
gi|122937347 pleckstrin homology domain containing, family M, me...   244   1e-64
gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo s...   149   6e-36
gi|156151402 hypothetical protein LOC80183 [Homo sapiens]             143   3e-34
gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens]    116   4e-26
gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens]    116   4e-26
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do...    45   2e-04
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do...    45   2e-04
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    45   2e-04
gi|33457316 pleckstrin homology domain containing, family O memb...    34   0.29 
gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit...    34   0.38 
gi|5174547 mitogen-activated protein kinase kinase kinase 5 [Hom...    33   0.64 
gi|150456471 doublecortin domain containing 2B [Homo sapiens]          33   0.84 
gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    32   1.1  
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]          32   1.4  
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]          32   1.4  
gi|7662230 ring finger protein 40 [Homo sapiens]                       32   1.4  
gi|7661946 IKK-related kinase epsilon [Homo sapiens]                   31   2.4  
gi|50083291 amyloid beta A4 precursor protein-binding, family B,...    31   3.2  
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    31   3.2  
gi|119709822 castor homolog 1, zinc finger isoform b [Homo sapiens]    31   3.2  
gi|50234893 pleckstrin homology domain containing, family A (pho...    31   3.2  
gi|31377720 pleckstrin homology domain containing, family A (pho...    31   3.2  
gi|38201692 RAS p21 protein activator 3 [Homo sapiens]                 31   3.2  
gi|118600965 hexaprenyldihydroxybenzoate methyltransferase [Homo...    30   4.2  
gi|117190334 PHD finger protein 16 [Homo sapiens]                      30   5.4  
gi|7662006 PHD finger protein 16 [Homo sapiens]                        30   5.4  
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             30   7.1  

>gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo
           sapiens]
          Length = 528

 Score = 1084 bits (2803), Expect = 0.0
 Identities = 528/528 (100%), Positives = 528/528 (100%)

Query: 1   MCPFLPLPPGLSNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENC 60
           MCPFLPLPPGLSNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENC
Sbjct: 1   MCPFLPLPPGLSNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENC 60

Query: 61  SLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVN 120
           SLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVN
Sbjct: 61  SLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVN 120

Query: 121 VQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLYLYMDRT 180
           VQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLYLYMDRT
Sbjct: 121 VQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLYLYMDRT 180

Query: 181 WMPYIFSLPLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKL 240
           WMPYIFSLPLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKL
Sbjct: 181 WMPYIFSLPLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKL 240

Query: 241 QAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVA 300
           QAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVA
Sbjct: 241 QAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVA 300

Query: 301 IPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDL 360
           IPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDL
Sbjct: 301 IPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDL 360

Query: 361 TKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRS 420
           TKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRS
Sbjct: 361 TKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRS 420

Query: 421 GALKELSKRLNHRNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQR 480
           GALKELSKRLNHRNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQR
Sbjct: 421 GALKELSKRLNHRNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQR 480

Query: 481 SFICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528
           SFICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR
Sbjct: 481 SFICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528


>gi|40538728 pleckstrin homology domain containing, family M (with RUN
            domain) member 1 [Homo sapiens]
          Length = 1056

 Score = 1033 bits (2671), Expect = 0.0
 Identities = 505/519 (97%), Positives = 509/519 (98%)

Query: 10   GLSNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG 69
            GLSNPF+GLMKLGTVER+GAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG
Sbjct: 527  GLSNPFRGLMKLGTVERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG 586

Query: 70   PAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEE 129
            PAHSDGRFELVFSGKKLALRASSQDEAEDWLD VREALQKVRPQQEDEWVNVQY DQPEE
Sbjct: 587  PAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNVQYPDQPEE 646

Query: 130  PPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLYLYMDRTWMPYIFSLP 189
            PPEAPQGCLSPSDLLSEPAALQGTQ DWSSAQVPE DAIKESLLYLYMDRTWMPYIFSL 
Sbjct: 647  PPEAPQGCLSPSDLLSEPAALQGTQFDWSSAQVPEPDAIKESLLYLYMDRTWMPYIFSLS 706

Query: 190  LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA 249
            LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA
Sbjct: 707  LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA 766

Query: 250  LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS 309
            LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS
Sbjct: 767  LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS 826

Query: 310  QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA 369
            QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA
Sbjct: 827  QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA 886

Query: 370  LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKR 429
            LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGR REQLKLLGDYLGLCRSGALKELSKR
Sbjct: 887  LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKR 946

Query: 430  LNHRNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQRSFICQICQH 489
            LNHRNYLLESPHRF VADL+QIAD VYEGFLKALIEFASQHVYHCDLCTQR FICQICQH
Sbjct: 947  LNHRNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQH 1006

Query: 490  HDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528
            HDIIFP EFDTTVRCA+CKTVFHQSCQAVVKKGCPRCAR
Sbjct: 1007 HDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCAR 1045


>gi|239756837 PREDICTED: similar to pleckstrin homology domain
           containing, family M (with RUN domain) member 1, partial
           [Homo sapiens]
          Length = 623

 Score =  877 bits (2267), Expect = 0.0
 Identities = 450/529 (85%), Positives = 460/529 (86%), Gaps = 19/529 (3%)

Query: 10  GLSNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG 69
           GLSNPF+GLMKLGTVER+GAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG
Sbjct: 93  GLSNPFRGLMKLGTVERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG 152

Query: 70  PAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEE 129
           PAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEE
Sbjct: 153 PAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEE 212

Query: 130 PPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLYLYMDRTWMPYIFSLP 189
           PPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPE DAIKESLLYLYMDRTWMPYIFSL 
Sbjct: 213 PPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPEPDAIKESLLYLYMDRTWMPYIFSLS 272

Query: 190 LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA 249
           LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA
Sbjct: 273 LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA 332

Query: 250 LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS 309
           LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS
Sbjct: 333 LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS 392

Query: 310 QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA 369
           QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA
Sbjct: 393 QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA 452

Query: 370 LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKR 429
           LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGR REQLKLLGDYLGLCRSGALKELSKR
Sbjct: 453 LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKR 512

Query: 430 LNHRNYLLESPHRFRVADL--------RQIADEVYEGFLKALIEFASQHVYHCDLCTQRS 481
               +  L++      A L        R   ++V  G    +    S       L  +  
Sbjct: 513 AGPESASLKTASSILAAVLPEPGLLRARVCLEQVPRGSQGVVKSLGSGGALSPSLVKEPG 572

Query: 482 FI--CQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528
                Q C              V CA+CKTVFHQSCQAVVKKGCPRCAR
Sbjct: 573 TCTGMQTCVD---------QMPVGCAECKTVFHQSCQAVVKKGCPRCAR 612


>gi|122937347 pleckstrin homology domain containing, family M,
           member 3 [Homo sapiens]
          Length = 761

 Score =  244 bits (623), Expect = 1e-64
 Identities = 167/535 (31%), Positives = 265/535 (49%), Gaps = 37/535 (6%)

Query: 15  FQGLMKLGTVE-RQGAMGIWKELFCELSPLEFRLYL--SNEEHTCVENCSLLRCESVGP- 70
           F  ++K G +E R+     W+  + ELSP     Y   S+          L   +S+   
Sbjct: 209 FPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVL 268

Query: 71  AHSDGRF--ELVFSGKKLALRASSQDEAEDW----LDLVREALQKVRPQQEDEWVNV--- 121
            + + R    +++   +L L+A S  EA DW     ++V  A+     +Q +  ++    
Sbjct: 269 GNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLG 328

Query: 122 QYSD--QPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLY-LYMD 178
            + D  Q     +   G L PS +L      Q              + +K   LY L + 
Sbjct: 329 HHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ--------------NILKSGTLYRLTVQ 374

Query: 179 RTWMPYIFSLPLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVL 238
             W  + F L    L  F+    ++    S+ V+    +  D   G  S F++I  + VL
Sbjct: 375 NNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVL 434

Query: 239 KLQAGNAEEAALWRDLVRKVLASYLETAEE--AVTLGGS-LDENCQEVLKFATREN--GF 293
           +L+A   + A  W + + K+ A+   ++E+   VTL     D+     L+   R++    
Sbjct: 435 RLRAETRQRAQEWMEAL-KIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTS 493

Query: 294 LLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPAR 353
            L  L  + +E+GL +Q   CAGC R IG S  + K+C +SG YYC  CH DD+ +IPAR
Sbjct: 494 FLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPAR 553

Query: 354 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGD 413
           I+HNWD +K  + +QA +FL  +  +PLI++Q  NA LY H E +  + R R++LK L  
Sbjct: 554 IVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRA 613

Query: 414 YLGLCRSGALKELSKRLNHRNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYH 473
           YL  CR+   ++L +R+  R YLL+  H + +ADL+Q+ +     FL  +I+FA+ HVY 
Sbjct: 614 YLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYS 673

Query: 474 CDLCTQRSFICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528
           C LC+Q+ FIC+IC + +I++P E  +T RC  C  VFH  C+      CPRC R
Sbjct: 674 CSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKE-KSVPCPRCVR 727



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 14/128 (10%)

Query: 5   LPLPPGL--SNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSL 62
           LP  P L  S  +Q ++K GT+ R      WK     LS    R YL   +   ++   L
Sbjct: 347 LPPSPVLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLS----RAYLMAFQPGKLDEDPL 402

Query: 63  LR-----CESVGPAHSDG---RFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQ 114
           L      C +V   + DG    F+++F    L LRA ++  A++W++ ++ A    R  +
Sbjct: 403 LSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSE 462

Query: 115 EDEWVNVQ 122
           ++  V ++
Sbjct: 463 QNLQVTLR 470


>gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo
           sapiens]
          Length = 512

 Score =  149 bits (376), Expect = 6e-36
 Identities = 77/236 (32%), Positives = 125/236 (52%), Gaps = 4/236 (1%)

Query: 296 QYLVAIPMEKGLDSQGCFCAGCSRQIGFSFV--RPKLCAFSGLYYCDICHQDDASVIPAR 353
           +Y + I  E GLDSQ   CA C   I    V    + C ++G YYC  CH +D +VIPAR
Sbjct: 260 EYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPAR 319

Query: 354 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGD 413
           ++HNWD   R + R ++++L  + ++P++ L+ +N  L+ +VE +  I + R+ + L+  
Sbjct: 320 VVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKP 379

Query: 414 YLGLCRSGALKELSKRLNHRNYLLESPHRFRVADLRQI-ADEVYEGFLKALIEFASQHVY 472
           Y   CR      L  +L  R + +E+   + V DL  + A  +     +    FA     
Sbjct: 380 YFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKL 439

Query: 473 HCDLCTQRSFICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528
            C+ C  + F+C++C+  D++FP +  T+V CA C  VFH+ C       CP+CAR
Sbjct: 440 DCERCQAKGFVCELCREGDVLFPFDSHTSV-CADCSAVFHRDCYYDNSTTCPKCAR 494


>gi|156151402 hypothetical protein LOC80183 [Homo sapiens]
          Length = 662

 Score =  143 bits (361), Expect = 3e-34
 Identities = 90/275 (32%), Positives = 134/275 (48%), Gaps = 18/275 (6%)

Query: 267 EEAVTLGGSLDENCQEVLKFATRENG--------FLLQYLVAIPMEKGL--DSQGCFCAG 316
           EE V        N  + +KF +R  G        F + + +  P+++ L   +Q  FCAG
Sbjct: 377 EECVRKDFESSMNVVQEIKFKSRIRGTEDWAPPRFQIIFNIHPPLKRDLVVAAQNFFCAG 436

Query: 317 CSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQ 375
           C   +   FV R + C + G Y+CD CH    S IPARI+  WD  K  +   + + L  
Sbjct: 437 CGTPVEPKFVKRLRYCEYLGKYFCDCCHSYAESCIPARILMMWDFKKYYVSNFSKQLLDS 496

Query: 376 IRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCR--SGALKELSKRLNHR 433
           I  QP+ NL  +  SLY   + +  +   +EQL  +   L  CR  + ALKE  +   H 
Sbjct: 497 IWHQPIFNLLSIGQSLYAKAKELDRVKEIQEQLFHIKKLLKTCRFANSALKEFEQVPGH- 555

Query: 434 NYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQRSFICQICQHHDII 493
             L +  H F + DL +I   +    LK +++ +  HV  C+LC  + FIC+ CQ+  +I
Sbjct: 556 --LTDELHLFSLEDLVRIKKGLLAPLLKDILKASLAHVAGCELCQGKGFICEFCQNTTVI 613

Query: 494 FPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528
           FP +  T  RC+ C+  FH+ C       CPRCAR
Sbjct: 614 FPFQTATCRRCSACRACFHKQC--FQSSECPRCAR 646


>gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens]
          Length = 927

 Score =  116 bits (291), Expect = 4e-26
 Identities = 70/219 (31%), Positives = 107/219 (48%), Gaps = 9/219 (4%)

Query: 314 CAGCSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKF 372
           CAGC  +    ++ R + C + G Y+C  CH++    IP+R++  WD +K  +   +   
Sbjct: 676 CAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDL 735

Query: 373 LTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKRLNH 432
           L +I   PL N+Q +N++LY  V+ ++ +   R QL  + +    CR    KEL    + 
Sbjct: 736 LIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCR--LAKELLDSFDT 793

Query: 433 -RNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQRSFICQICQHH- 490
              +L E  H + + DL           L  L    + HV  C LC  + FIC+ CQ+  
Sbjct: 794 VPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNED 853

Query: 491 DIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKG-CPRCAR 528
           DIIFP E      C +CK  +H++C    K G CPRC R
Sbjct: 854 DIIFPFELHKCRTCEECKACYHKAC---FKSGSCPRCER 889


>gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens]
          Length = 972

 Score =  116 bits (291), Expect = 4e-26
 Identities = 70/219 (31%), Positives = 107/219 (48%), Gaps = 9/219 (4%)

Query: 314 CAGCSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKF 372
           CAGC  +    ++ R + C + G Y+C  CH++    IP+R++  WD +K  +   +   
Sbjct: 721 CAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDL 780

Query: 373 LTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKRLNH 432
           L +I   PL N+Q +N++LY  V+ ++ +   R QL  + +    CR    KEL    + 
Sbjct: 781 LIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCR--LAKELLDSFDT 838

Query: 433 -RNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQRSFICQICQHH- 490
              +L E  H + + DL           L  L    + HV  C LC  + FIC+ CQ+  
Sbjct: 839 VPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNED 898

Query: 491 DIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKG-CPRCAR 528
           DIIFP E      C +CK  +H++C    K G CPRC R
Sbjct: 899 DIIFPFELHKCRTCEECKACYHKAC---FKSGSCPRCER 934


>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH
           domain 1 isoform d [Homo sapiens]
          Length = 1133

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/126 (26%), Positives = 64/126 (50%), Gaps = 6/126 (4%)

Query: 8   PPGLSNPFQGLMKLGTVERQGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRC 65
           PPG S P   ++K G +++    G  I+++ +  L     R + SN++       S+  C
Sbjct: 73  PPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-C 131

Query: 66  ESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL--QKVRPQQEDEW-VNVQ 122
            S   A  D +FE++ + +  A RA S  E ++W+  +++A+  Q+ R +    + + V 
Sbjct: 132 ISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP 191

Query: 123 YSDQPE 128
            S+QP+
Sbjct: 192 GSEQPD 197


>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
           domain 1 isoform a [Homo sapiens]
          Length = 1205

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/126 (26%), Positives = 64/126 (50%), Gaps = 6/126 (4%)

Query: 8   PPGLSNPFQGLMKLGTVERQGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRC 65
           PPG S P   ++K G +++    G  I+++ +  L     R + SN++       S+  C
Sbjct: 73  PPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-C 131

Query: 66  ESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL--QKVRPQQEDEW-VNVQ 122
            S   A  D +FE++ + +  A RA S  E ++W+  +++A+  Q+ R +    + + V 
Sbjct: 132 ISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP 191

Query: 123 YSDQPE 128
            S+QP+
Sbjct: 192 GSEQPD 197


>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
           1 isoform c [Homo sapiens]
          Length = 1450

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/126 (26%), Positives = 64/126 (50%), Gaps = 6/126 (4%)

Query: 8   PPGLSNPFQGLMKLGTVERQGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRC 65
           PPG S P   ++K G +++    G  I+++ +  L     R + SN++       S+  C
Sbjct: 318 PPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-C 376

Query: 66  ESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL--QKVRPQQEDEW-VNVQ 122
            S   A  D +FE++ + +  A RA S  E ++W+  +++A+  Q+ R +    + + V 
Sbjct: 377 ISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP 436

Query: 123 YSDQPE 128
            S+QP+
Sbjct: 437 GSEQPD 442


>gi|33457316 pleckstrin homology domain containing, family O member
           2 [Homo sapiens]
          Length = 490

 Score = 34.3 bits (77), Expect = 0.29
 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 10/108 (9%)

Query: 20  KLGTVERQ--GAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSL---LRCESV-GPAHS 73
           K G +++   G +G WK+ +  L   +  +Y + ++  CVE   L    +C+ +      
Sbjct: 21  KAGWIKKSSGGLLGFWKDRYLLLCQAQLLVYENEDDQKCVETVELGSYEKCQDLRALLKR 80

Query: 74  DGRFELVFS-GKKLA---LRASSQDEAEDWLDLVREALQKVRPQQEDE 117
             RF L+ S G K++    +A + +E E W+  + E + + + +  DE
Sbjct: 81  KHRFILLRSPGNKVSDIKFQAPTGEEKESWIKALNEGINRGKNKAFDE 128


>gi|158631203 dual adaptor of phosphotyrosine and
           3-phosphoinositides [Homo sapiens]
          Length = 280

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 8/112 (7%)

Query: 5   LPLPPGLSNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLR 64
           +P  P L      L K G     G +  WK  +  L   E + +        +    L  
Sbjct: 158 VPTAPSLGTKEGYLTKQG-----GLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTE 212

Query: 65  CESVGPAHSDGR---FELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQ 113
           C +V   +S  R   F LVF  +   L A +  EA++W+ ++R  L ++R Q
Sbjct: 213 CSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQ 264


>gi|5174547 mitogen-activated protein kinase kinase kinase 5 [Homo
            sapiens]
          Length = 1374

 Score = 33.1 bits (74), Expect = 0.64
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 107  LQKVRPQQEDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELD 166
            L +   +++ E  +++   QP E PE P   L+ S   +E + L    +DW      + D
Sbjct: 1270 LHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNTEDSEL----TDWLRVNGADED 1325

Query: 167  AIKESLLYLYMDRTWMPYIFSLPLEALKCFRIR 199
             I     +L  D T +  ++ +  + LKC R+R
Sbjct: 1326 TISR---FLAEDYTLLDVLYYVTRDDLKCLRLR 1355


>gi|150456471 doublecortin domain containing 2B [Homo sapiens]
          Length = 349

 Score = 32.7 bits (73), Expect = 0.84
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 115 EDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEP--AALQGTQSDWSSAQVPELDAIKESL 172
           EDE+ ++ Y +     P  P+GC  P    S P     QG ++  +     E D IK S 
Sbjct: 202 EDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSA 261

Query: 173 LYLYMDRTWMP 183
            Y    +T  P
Sbjct: 262 FYARPQQTIQP 272


>gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
           2 [Homo sapiens]
          Length = 1704

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/61 (24%), Positives = 28/61 (45%)

Query: 48  YLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL 107
           Y +NE+    +    L   S      D +FE+V + +    R   ++E  DW+ ++  AL
Sbjct: 514 YYNNEKEMYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNAL 573

Query: 108 Q 108
           +
Sbjct: 574 K 574


>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
          Length = 1291

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 4/51 (7%)

Query: 77  FELVFSGKKLALRASSQDEAEDWLD----LVREALQKVRPQQEDEWVNVQY 123
           + + F  K L+L+A+S+DE   W+     L+ + LQ   P Q + W+  Q+
Sbjct: 111 YGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQF 161


>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
          Length = 1290

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 4/51 (7%)

Query: 77  FELVFSGKKLALRASSQDEAEDWLD----LVREALQKVRPQQEDEWVNVQY 123
           + + F  K L+L+A+S+DE   W+     L+ + LQ   P Q + W+  Q+
Sbjct: 111 YGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQF 161


>gi|7662230 ring finger protein 40 [Homo sapiens]
          Length = 1001

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 11/133 (8%)

Query: 49  LSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQ 108
           LS EE T       +R   +          L F  KKLA R   +   ED L   RE ++
Sbjct: 22  LSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDEL---RERIE 78

Query: 109 KVRPQQEDEWVNV----QYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQS----DWSSA 160
           K+  +Q  +   +    +Y  Q +E  EA   C      LS      GTQ     D +  
Sbjct: 79  KLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSSAPEAPGTQEGPTCDGTPL 138

Query: 161 QVPELDAIKESLL 173
             P    +++ LL
Sbjct: 139 PEPGTSELRDPLL 151


>gi|7661946 IKK-related kinase epsilon [Homo sapiens]
          Length = 716

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)

Query: 384 LQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRS---GALKELSKRLNHRNYLL 437
           +Q   ASL  H +RM ++  +R  L+L+G  +  C +   G  + LSK L   ++ L
Sbjct: 597 VQKYQASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQL 653


>gi|50083291 amyloid beta A4 precursor protein-binding, family B,
           member 2 [Homo sapiens]
          Length = 736

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 22/93 (23%), Positives = 33/93 (35%), Gaps = 14/93 (15%)

Query: 94  DEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEEPP--------------EAPQGCLS 139
           DE   W  L +++     P + D W +  +   P+ PP                P G   
Sbjct: 257 DEESSWTTLSQDSASPSSPDETDIWSDHSFQTDPDLPPGWKRVSDIAGTYYWHIPTGTTQ 316

Query: 140 PSDLLSEPAALQGTQSDWSSAQVPELDAIKESL 172
               +S PA LQG++    S+  P      E L
Sbjct: 317 WERPVSIPADLQGSRKGSLSSVTPSPTPENEDL 349


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 23/69 (33%)

Query: 116 DEWVNVQYSDQP--------------EEPPEA-----PQGCLSPSDLLSEPA----ALQG 152
           ++WVN +YS++P              E PPE      PQGC    D   EP+    AL+ 
Sbjct: 89  EKWVNGEYSEEPAPTPVLGRIAREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEE 148

Query: 153 TQSDWSSAQ 161
             SD ++++
Sbjct: 149 KDSDGAASK 157


>gi|119709822 castor homolog 1, zinc finger isoform b [Homo sapiens]
          Length = 1166

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 23/69 (33%)

Query: 116 DEWVNVQYSDQP--------------EEPPEA-----PQGCLSPSDLLSEPA----ALQG 152
           ++WVN +YS++P              E PPE      PQGC    D   EP+    AL+ 
Sbjct: 89  EKWVNGEYSEEPAPTPVLGRIAREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEE 148

Query: 153 TQSDWSSAQ 161
             SD ++++
Sbjct: 149 KDSDGAASK 157


>gi|50234893 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 1 [Homo
           sapiens]
          Length = 404

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 11/111 (9%)

Query: 4   FLPLPPGLSNPFQGLMKLGTVERQGA-MGIWKELFCELSPLEFRLYLSNEEHTCV----- 57
           F P PP  S     ++K G   +QGA M  WK  + +L       + S  E   +     
Sbjct: 182 FTPKPPQDS----AVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPL 237

Query: 58  -ENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL 107
            E   +  C+       D  FE+V + +   ++A S +E   W+  V  A+
Sbjct: 238 KEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAI 288


>gi|31377720 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 1 [Homo
           sapiens]
          Length = 404

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 11/111 (9%)

Query: 4   FLPLPPGLSNPFQGLMKLGTVERQGA-MGIWKELFCELSPLEFRLYLSNEEHTCV----- 57
           F P PP  S     ++K G   +QGA M  WK  + +L       + S  E   +     
Sbjct: 182 FTPKPPQDS----AVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPL 237

Query: 58  -ENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL 107
            E   +  C+       D  FE+V + +   ++A S +E   W+  V  A+
Sbjct: 238 KEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAI 288


>gi|38201692 RAS p21 protein activator 3 [Homo sapiens]
          Length = 834

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 10/73 (13%)

Query: 196 FRIRNNEKMLSDSHGVETIRDI----------LPDTSLGGPSFFKIITAKAVLKLQAGNA 245
           FR+ N+E     S G + +  I          L + S    + F++I  +  L +QA N 
Sbjct: 603 FRLTNHEFTYHKSKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQANNC 662

Query: 246 EEAALWRDLVRKV 258
            EA  W D++ KV
Sbjct: 663 VEAKDWIDILTKV 675


>gi|118600965 hexaprenyldihydroxybenzoate methyltransferase [Homo
           sapiens]
          Length = 369

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 432 HRNY--LLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYHCDLCTQRSFICQICQH 489
           H+++  +L+    +RV  L +I +E  E F   +     +HV   DL T     CQ+ + 
Sbjct: 187 HKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHV--IDLETFLQCCCQVLKP 244

Query: 490 HDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKG 522
              +F +  + T        VF +   ++V KG
Sbjct: 245 GGSLFITTINKTQLSYALGIVFSEQIASIVPKG 277


>gi|117190334 PHD finger protein 16 [Homo sapiens]
          Length = 823

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 13/38 (34%), Positives = 19/38 (50%), Gaps = 3/38 (7%)

Query: 483 ICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVK 520
           IC +C+  D     E +  V C KC    HQ+C  ++K
Sbjct: 202 ICDVCRSPD---SEEGNDMVFCDKCNVCVHQACYGILK 236


>gi|7662006 PHD finger protein 16 [Homo sapiens]
          Length = 823

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 13/38 (34%), Positives = 19/38 (50%), Gaps = 3/38 (7%)

Query: 483 ICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVK 520
           IC +C+  D     E +  V C KC    HQ+C  ++K
Sbjct: 202 ICDVCRSPD---SEEGNDMVFCDKCNVCVHQACYGILK 236


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 29.6 bits (65), Expect = 7.1
 Identities = 14/54 (25%), Positives = 21/54 (38%), Gaps = 8/54 (14%)

Query: 473  HCDLCTQRSFICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRC 526
            H + C   +  CQ CQHH            RC +C+  ++   Q    + C  C
Sbjct: 1164 HSEACEPETGACQGCQHH--------TEGPRCEQCQPGYYGDAQRGTPQDCQLC 1209


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,219,386
Number of Sequences: 37866
Number of extensions: 972836
Number of successful extensions: 3109
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3054
Number of HSP's gapped (non-prelim): 65
length of query: 528
length of database: 18,247,518
effective HSP length: 107
effective length of query: 421
effective length of database: 14,195,856
effective search space: 5976455376
effective search space used: 5976455376
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.