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Search of human proteins with 239751284
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751284 PREDICTED: hypothetical protein XP_002347797 [Homo
sapiens]
(1674 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239751284 PREDICTED: hypothetical protein XP_002347797 [Homo ... 3410 0.0
gi|93352554 GPR158-like 1 [Homo sapiens] 2874 0.0
gi|93204867 G protein-coupled receptor 158 [Homo sapiens] 160 1e-38
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 62 5e-09
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 62 5e-09
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 62 5e-09
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 62 5e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 60 2e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 53 2e-06
gi|38176300 nestin [Homo sapiens] 52 6e-06
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ... 50 2e-05
gi|221139761 zinc finger protein 853 [Homo sapiens] 46 3e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 45 8e-04
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 45 8e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 44 0.001
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 44 0.002
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 43 0.002
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 43 0.002
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 43 0.003
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 43 0.003
gi|221316599 chromogranin B precursor [Homo sapiens] 43 0.003
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 43 0.003
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 42 0.004
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 42 0.004
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 42 0.004
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 42 0.004
gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens] 42 0.004
gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens] 42 0.004
gi|150418009 transforming, acidic coiled-coil containing protein... 42 0.004
gi|120953251 neuron navigator 3 [Homo sapiens] 42 0.005
>gi|239751284 PREDICTED: hypothetical protein XP_002347797 [Homo
sapiens]
Length = 1674
Score = 3410 bits (8843), Expect = 0.0
Identities = 1674/1674 (100%), Positives = 1674/1674 (100%)
Query: 1 MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAAL 60
MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAAL
Sbjct: 1 MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAAL 60
Query: 61 AYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRE 120
AYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRE
Sbjct: 61 AYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRE 120
Query: 121 SSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSG 180
SSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSG
Sbjct: 121 SSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSG 180
Query: 181 NWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGR 240
NWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGR
Sbjct: 181 NWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGR 240
Query: 241 LRPGWLITLSATFYGLKPDLSPEVXXXXXXLLPALAPTPAPALAPVPVSPQSPNLLTYIC 300
LRPGWLITLSATFYGLKPDLSPEV LLPALAPTPAPALAPVPVSPQSPNLLTYIC
Sbjct: 241 LRPGWLITLSATFYGLKPDLSPEVXXXXXXLLPALAPTPAPALAPVPVSPQSPNLLTYIC 300
Query: 301 PWENAELPAKQENVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDAH 360
PWENAELPAKQENVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDAH
Sbjct: 301 PWENAELPAKQENVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDAH 360
Query: 361 HQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESPEG 420
HQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESPEG
Sbjct: 361 HQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESPEG 420
Query: 421 QNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGS 480
QNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGS
Sbjct: 421 QNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGS 480
Query: 481 REQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSL 540
REQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSL
Sbjct: 481 REQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSL 540
Query: 541 GSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEA 600
GSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEA
Sbjct: 541 GSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEA 600
Query: 601 RGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSV 660
RGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSV
Sbjct: 601 RGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSV 660
Query: 661 EARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKAT 720
EARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKAT
Sbjct: 661 EARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKAT 720
Query: 721 FWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAI 780
FWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAI
Sbjct: 721 FWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAI 780
Query: 781 QKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQE 840
QKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQE
Sbjct: 781 QKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQE 840
Query: 841 SVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEIC 900
SVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEIC
Sbjct: 841 SVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEIC 900
Query: 901 PWEVNERTREEWTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWES 960
PWEVNERTREEWTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWES
Sbjct: 901 PWEVNERTREEWTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWES 960
Query: 961 VDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGA 1020
VDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGA
Sbjct: 961 VDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGA 1020
Query: 1021 GEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACS 1080
GEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACS
Sbjct: 1021 GEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACS 1080
Query: 1081 QHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQ 1140
QHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQ
Sbjct: 1081 QHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQ 1140
Query: 1141 KAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISD 1200
KAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISD
Sbjct: 1141 KAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISD 1200
Query: 1201 LPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHE 1260
LPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHE
Sbjct: 1201 LPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHE 1260
Query: 1261 LQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSS 1320
LQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSS
Sbjct: 1261 LQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSS 1320
Query: 1321 AKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEA 1380
AKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEA
Sbjct: 1321 AKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEA 1380
Query: 1381 VCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPW 1440
VCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPW
Sbjct: 1381 VCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPW 1440
Query: 1441 EAGGGAAEEGEQERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQEAVCPGEGTGSGGL 1500
EAGGGAAEEGEQERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQEAVCPGEGTGSGGL
Sbjct: 1441 EAGGGAAEEGEQERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQEAVCPGEGTGSGGL 1500
Query: 1501 LPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEGNKIKGTMADICPGEETGVPSEE 1560
LPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEGNKIKGTMADICPGEETGVPSEE
Sbjct: 1501 LPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEGNKIKGTMADICPGEETGVPSEE 1560
Query: 1561 SGLLALTATRREFFPTAPEKPLCLLVHGPLDHFFPESKIPCPKVSRPASTFTLEGVRELQ 1620
SGLLALTATRREFFPTAPEKPLCLLVHGPLDHFFPESKIPCPKVSRPASTFTLEGVRELQ
Sbjct: 1561 SGLLALTATRREFFPTAPEKPLCLLVHGPLDHFFPESKIPCPKVSRPASTFTLEGVRELQ 1620
Query: 1621 GPSGLEPRTSLAPEPSLQEAESQSSSLTEDSGQVAFEAQYEEFTPPTVYPWDWE 1674
GPSGLEPRTSLAPEPSLQEAESQSSSLTEDSGQVAFEAQYEEFTPPTVYPWDWE
Sbjct: 1621 GPSGLEPRTSLAPEPSLQEAESQSSSLTEDSGQVAFEAQYEEFTPPTVYPWDWE 1674
>gi|93352554 GPR158-like 1 [Homo sapiens]
Length = 2367
Score = 2874 bits (7451), Expect = 0.0
Identities = 1404/1404 (100%), Positives = 1404/1404 (100%)
Query: 271 LLPALAPTPAPALAPVPVSPQSPNLLTYICPWENAELPAKQENVPQEGPSGPERGHHSPA 330
LLPALAPTPAPALAPVPVSPQSPNLLTYICPWENAELPAKQENVPQEGPSGPERGHHSPA
Sbjct: 964 LLPALAPTPAPALAPVPVSPQSPNLLTYICPWENAELPAKQENVPQEGPSGPERGHHSPA 1023
Query: 331 PARARLWRALSVAVEKSRAGENEMDAEDAHHQREANDVDEDRPKIFPKSHSLKAPVQQGS 390
PARARLWRALSVAVEKSRAGENEMDAEDAHHQREANDVDEDRPKIFPKSHSLKAPVQQGS
Sbjct: 1024 PARARLWRALSVAVEKSRAGENEMDAEDAHHQREANDVDEDRPKIFPKSHSLKAPVQQGS 1083
Query: 391 MRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAA 450
MRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAA
Sbjct: 1084 MRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAA 1143
Query: 451 LIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAML 510
LIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAML
Sbjct: 1144 LIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAML 1203
Query: 511 RQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAE 570
RQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAE
Sbjct: 1204 RQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAE 1263
Query: 571 ICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPW 630
ICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPW
Sbjct: 1264 ICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPW 1323
Query: 631 ESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPW 690
ESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPW
Sbjct: 1324 ESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPW 1383
Query: 691 EASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSI 750
EASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSI
Sbjct: 1384 EASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSI 1443
Query: 751 QAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQ 810
QAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQ
Sbjct: 1444 QAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQ 1503
Query: 811 EKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLC 870
EKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLC
Sbjct: 1504 EKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLC 1563
Query: 871 NGGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKM 930
NGGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKM
Sbjct: 1564 NGGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKM 1623
Query: 931 PGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGS 990
PGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGS
Sbjct: 1624 PGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGS 1683
Query: 991 KAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRER 1050
KAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRER
Sbjct: 1684 KAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRER 1743
Query: 1051 AVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCP 1110
AVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCP
Sbjct: 1744 AVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCP 1803
Query: 1111 WEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGM 1170
WEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGM
Sbjct: 1804 WEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGM 1863
Query: 1171 AKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTG 1230
AKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTG
Sbjct: 1864 AKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTG 1923
Query: 1231 SFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKAS 1290
SFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKAS
Sbjct: 1924 SFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKAS 1983
Query: 1291 SQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQE 1350
SQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQE
Sbjct: 1984 SQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQE 2043
Query: 1351 EKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEA 1410
EKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEA
Sbjct: 2044 EKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEA 2103
Query: 1411 AGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPG 1470
AGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPG
Sbjct: 2104 AGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPG 2163
Query: 1471 GTEEHFSKAAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQ 1530
GTEEHFSKAAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQ
Sbjct: 2164 GTEEHFSKAAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQ 2223
Query: 1531 WEITDPEGNKIKGTMADICPGEETGVPSEESGLLALTATRREFFPTAPEKPLCLLVHGPL 1590
WEITDPEGNKIKGTMADICPGEETGVPSEESGLLALTATRREFFPTAPEKPLCLLVHGPL
Sbjct: 2224 WEITDPEGNKIKGTMADICPGEETGVPSEESGLLALTATRREFFPTAPEKPLCLLVHGPL 2283
Query: 1591 DHFFPESKIPCPKVSRPASTFTLEGVRELQGPSGLEPRTSLAPEPSLQEAESQSSSLTED 1650
DHFFPESKIPCPKVSRPASTFTLEGVRELQGPSGLEPRTSLAPEPSLQEAESQSSSLTED
Sbjct: 2284 DHFFPESKIPCPKVSRPASTFTLEGVRELQGPSGLEPRTSLAPEPSLQEAESQSSSLTED 2343
Query: 1651 SGQVAFEAQYEEFTPPTVYPWDWE 1674
SGQVAFEAQYEEFTPPTVYPWDWE
Sbjct: 2344 SGQVAFEAQYEEFTPPTVYPWDWE 2367
Score = 543 bits (1398), Expect = e-154
Identities = 264/264 (100%), Positives = 264/264 (100%)
Query: 1 MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAAL 60
MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAAL
Sbjct: 1 MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAAL 60
Query: 61 AYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRE 120
AYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRE
Sbjct: 61 AYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRE 120
Query: 121 SSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSG 180
SSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSG
Sbjct: 121 SSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSG 180
Query: 181 NWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGR 240
NWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGR
Sbjct: 181 NWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGR 240
Query: 241 LRPGWLITLSATFYGLKPDLSPEV 264
LRPGWLITLSATFYGLKPDLSPEV
Sbjct: 241 LRPGWLITLSATFYGLKPDLSPEV 264
>gi|93204867 G protein-coupled receptor 158 [Homo sapiens]
Length = 1215
Score = 160 bits (404), Expect = 1e-38
Identities = 95/228 (41%), Positives = 131/228 (57%), Gaps = 19/228 (8%)
Query: 50 QVPLEGAEAALAYLYSGDAQQLSQVNCSERYEARGA-GAMPGLP---PSLQGAAGTLAQA 105
+VP++ A +YLY+GD+ QL + NCS RYE G G P L PSL A TL A
Sbjct: 77 EVPMDVA----SYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHA 132
Query: 106 ANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPP-GASHLQLAL 164
NFLN++LQ+N RE ++++D++WYQALV S+ EG+P + RA +TF+ A Q+ L
Sbjct: 133 TNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFSTDSLSAPAPQVFL 192
Query: 165 QATRTGEETILQDLSGNWVQEENPPGDLD---------TPALKKRVLTNDLGSLGSPKWP 215
QATR +LQDLS + N + + P L +R LG W
Sbjct: 193 QATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPNQGPRGLGH-SWR 251
Query: 216 QADGYVGDTQQVRLSPPFLECQEGRLRPGWLITLSATFYGLKPDLSPE 263
+ DG GD + SPP+LEC+ G +PGWL+TLS+ YGL+P+L PE
Sbjct: 252 RKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPE 299
Score = 51.2 bits (121), Expect = 8e-06
Identities = 106/476 (22%), Positives = 165/476 (34%), Gaps = 125/476 (26%)
Query: 1149 QREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSE 1208
Q+++ +KG LG + + + ++ + C E+K+ + + S
Sbjct: 741 QKKRCSKKG----LGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESS 796
Query: 1209 VAEGHSLEATEKGDLRQDPKTGSFPEHI---TQEKA--PAADTEEFTTED-------GEK 1256
G S E T K + K+ S +H+ T+E + P EE TTE+ G+K
Sbjct: 797 GNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKK 856
Query: 1257 TSHELQSVCPWETT---------APADSVSHLDRQRPDQPKAS----SQRLVSTGGRAAD 1303
+ +L+ E+T A A ++S ++ P+ S S ++++
Sbjct: 857 LTQKLKEDSEAESTESVPLVCKSASAHNLS--SEKKTGHPRTSMLQKSLSVIASAKEKTL 914
Query: 1304 VCPWDVPDAGVYKSDSSAKAETCPWEVTERIPV-KGVSRQDGKGDSQEEKGRAPEKSEPK 1362
AGV + S K +P K +R D+ E K AP+ S P
Sbjct: 915 GLAGKTQTAGVEERTKSQKP----------LPKDKETNRNHSNSDNTETKDPAPQNSNPA 964
Query: 1363 GVPVQKKPEMADFRQQEAV-------------------------CPWESQDGKGLSPQPA 1397
P +KP+ + +Q+ V CPWE D L+P P
Sbjct: 965 EEP--RKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYD---LTPGPV 1019
Query: 1398 PDASDRSRGSSEAAGSVET--------------RVAEVCLWEVVEAPSAKKAEICPWEAG 1443
P S + S A +E + AEVC + KAE+C WE+
Sbjct: 1020 PSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVC--QQSNQKRIDKAEVCLWESQ 1077
Query: 1444 GGAAEEGE-----------QERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQEAVCPG 1492
G + E E + + + G+ G +EE KA A E E
Sbjct: 1078 GQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENEN---- 1133
Query: 1493 EGTGSGGLLPQSGALDPELKVSPKEAGSMGS------------RMAELCQWEITDP 1536
L Q G E K S E GS AE+C WE P
Sbjct: 1134 --------LNQIG--HQEKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETP 1179
Score = 50.4 bits (119), Expect = 1e-05
Identities = 104/527 (19%), Positives = 187/527 (35%), Gaps = 71/527 (13%)
Query: 322 PERGHHSPAPARARLWRALSVAVEKSRAGE---NEMDAEDAHHQREANDVDEDRPKIFPK 378
P+ H S P A ++ R+G + +++ + H + D+ ++ K++ +
Sbjct: 665 PKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQ 724
Query: 379 SHSLKAPV--------------QQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSG 424
K ++G RS+ I + + S KE E + G G
Sbjct: 725 LEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKG 784
Query: 425 TAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQ---QNAHTSRMLQVCQREGSR 481
TA P S G+ K + + + S + Q +S + Q E +
Sbjct: 785 TALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETT 844
Query: 482 EQED----RGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGL 537
E G+++TQ L E +E + ++ + + N+ K+T + + L
Sbjct: 845 ENSTLESLSGKKLTQKLKE-DSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSL 903
Query: 538 QSLGSADHRVAEVCPW-------EVTESETRQPD----SGNKAEICPWETSEGAPESRAL 586
+ SA + + E T+S+ P + N + ET + AP++
Sbjct: 904 SVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNP 963
Query: 587 RQDPGDSQK----KRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGS 642
++P QK K+ + D+ P + + + VCPWE D L+PG
Sbjct: 964 AEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNF--DIGEVCPWEVYD---LTPGP 1018
Query: 643 APQDPGRIRDKSEAGDSVEARKVEK-PGWEAAGPEAHTPD------------ITKAEPCP 689
P + K + S+ A ++EK P + H P I KAE C
Sbjct: 1019 VPSE-----SKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCL 1073
Query: 690 WEASEGG--EDGKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPW---ESTDFRG 744
WE+ ED K LP+ ++ G E L P T+
Sbjct: 1074 WESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENEN 1133
Query: 745 PSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELD 791
+ + Q +S ++ ++ P +AE+CPWE +
Sbjct: 1134 LNQIGHQEKKTSSSEENVRGSYNSSNNFQQ---PLTSRAEVCPWEFE 1177
Score = 46.2 bits (108), Expect = 3e-04
Identities = 101/486 (20%), Positives = 174/486 (35%), Gaps = 61/486 (12%)
Query: 492 QGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSAD------- 544
+GLG R + + RQ S++ T G + K +S G+
Sbjct: 748 KGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETL 807
Query: 545 -HRVAEVCPWEVTESETRQPDSGNKAEICPWETSEG-APESRALRQDPGDSQKKRGEARG 602
+RV + T R D ++ P E+ E E+ L G ++ +
Sbjct: 808 KNRVFSLKKSHSTYDHVR--DQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDS 865
Query: 603 KSEPIDVVPMMRKKPE--RLVREQEAVCPWESADRGGLSP-GSAPQDPGRIRDKSEAGDS 659
++E + VP++ K L E++ P S + LS SA + + K++
Sbjct: 866 EAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGV 925
Query: 660 VEARKVEKP---GWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKT 716
E K +KP E +++ + +P P ++ E KP + + ++Q+
Sbjct: 926 EERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKSGI----MKQQRV 981
Query: 717 RKATFWKEQKPGG-------DLESLCPWESTDFRG---PSAVSIQAPGS---SECSGSLG 763
T + PG D+ +CPWE D PS +Q S SE +
Sbjct: 982 NPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPT 1041
Query: 764 SGI----------AEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKE 813
+ AEVC + + I KAE+C WE + ++ L + L E+
Sbjct: 1042 FSLKEKSHHKPKAAEVC--QQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERA 1099
Query: 814 KASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGG 873
K G +A + Q E + P+ +S + + ++ G Q
Sbjct: 1100 KEENGGQ--------PRAANVCAGQSEELPPK-----AVASKTENENLNQIGHQEKKTSS 1146
Query: 874 SRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTR-EEWTSAQVPRGGESQKDKEKMPG 932
S V + Q+ ++ E+CPWE + S +P +K P
Sbjct: 1147 SE-ENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANKIAGPR 1205
Query: 933 KSEIED 938
K EI D
Sbjct: 1206 KEEIWD 1211
Score = 41.2 bits (95), Expect = 0.009
Identities = 69/320 (21%), Positives = 116/320 (36%), Gaps = 62/320 (19%)
Query: 1140 QKAGSESAEQREKALE-KGRLTSLG-EDVSKGMAKLCQQQETICIWENKDLRESPAQAPK 1197
QK+ S A +EK L G+ + G E+ +K L + +ET N D E+ AP+
Sbjct: 900 QKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQ 959
Query: 1198 ISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKT 1257
+S AE + R+ K+G + +D TT+ K
Sbjct: 960 --------NSNPAE----------EPRKPQKSGIMKQQRVNPTTANSDLNPGTTQ--MKD 999
Query: 1258 SHELQSVCPWE----TTAPADSVSHLDR-------QRPDQPKASSQRLVSTGGRAADVCP 1306
+ ++ VCPWE T P S S + + + P S + +AA+VC
Sbjct: 1000 NFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQ 1059
Query: 1307 WDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPV 1366
KAE C WE + ++ K E+ + +P+ V
Sbjct: 1060 QS-------NQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAANV 1112
Query: 1367 -----QKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEV 1421
++ P A + E E+ + G + + + RGS ++ + +
Sbjct: 1113 CAGQSEELPPKAVASKTEN----ENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQ----- 1163
Query: 1422 CLWEVVEAPSAKKAEICPWE 1441
P +AE+CPWE
Sbjct: 1164 --------PLTSRAEVCPWE 1175
Score = 39.7 bits (91), Expect = 0.025
Identities = 48/232 (20%), Positives = 82/232 (35%), Gaps = 45/232 (19%)
Query: 1110 PWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDV--S 1167
P Q + ++CPWEV + T G + + +EK SL E
Sbjct: 992 PGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHK 1051
Query: 1168 KGMAKLCQQQET-------ICIWENKD--------------------LRESPAQAPKISD 1200
A++CQQ +C+WE++ +E P+ ++
Sbjct: 1052 PKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAAN 1111
Query: 1201 LPSSMSSEVAEGHSLEATEKGDLRQ----DPKTGSFPEHITQEKAPAADTEEFTTEDGEK 1256
+ + S E+ TE +L Q + KT S E++ + + ++ T E
Sbjct: 1112 VCAGQSEELPPKAVASKTENENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQPLTSRAE- 1170
Query: 1257 TSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWD 1308
VCPWE PA + P S+ ++ G R ++ WD
Sbjct: 1171 -------VCPWEFETPAQPNAGRSVALPASSALSANKI--AGPRKEEI--WD 1211
Score = 38.1 bits (87), Expect = 0.072
Identities = 92/433 (21%), Positives = 153/433 (35%), Gaps = 61/433 (14%)
Query: 808 SLQEKEKASRKGSFGEMGEQTVK----AVQKLSQQQESVCPRESTVPGHSSPCLDNSSSK 863
+L K G+ G+ E+T+K +++K + V R+ T S P
Sbjct: 786 ALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHV--RDQTEESSSLPTESQEEET 843
Query: 864 AGSQFLCN-GGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGE 922
+ L + G + TQ +ED E+ E+ P +C E + PR
Sbjct: 844 TENSTLESLSGKKLTQKL-KEDSEAESTESVPL---VCKSASAHNLSSEKKTGH-PRTSM 898
Query: 923 SQKD-------KEK---MPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRP 972
QK KEK + GK++ V K + + K + S + + P P
Sbjct: 899 LQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAP 958
Query: 973 QDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKA---------EICPWEV-----GA 1018
Q++ + + S K + P +L G E+CPWEV G
Sbjct: 959 QNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGP 1018
Query: 1019 GAGEER-----ALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGS 1073
E + ++ A + K+P + K + P+ A + QK + EV C W S
Sbjct: 1019 VPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPK-AAEVCQQSNQKRIDKAEV-CLWES 1076
Query: 1074 VGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGT 1133
G L + P + + G +P A + ++ P V+ T
Sbjct: 1077 QGQSILEDEK-LLISKTPVLPERAKEENGGQP------RAANVCAGQSEELPPKAVASKT 1129
Query: 1134 TGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPA 1193
+ L+Q E + +G S S + + +C WE E+PA
Sbjct: 1130 ENENLNQIGHQEKKTSSSEENVRGSYNS-----SNNFQQPLTSRAEVCPWE----FETPA 1180
Query: 1194 Q--APKISDLPSS 1204
Q A + LP+S
Sbjct: 1181 QPNAGRSVALPAS 1193
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 62.0 bits (149), Expect = 5e-09
Identities = 95/414 (22%), Positives = 153/414 (36%), Gaps = 33/414 (7%)
Query: 1199 SDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTS 1258
+DLPSSM E A+ + +A + G+ P TG ++ K+P E +
Sbjct: 115 ADLPSSMK-EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
Query: 1259 HELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSD 1318
E SV + A VS + +SS G+ + V P V + V +
Sbjct: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS-VKPAQVKASSVSTKE 232
Query: 1319 SSA-KAETCPW---EVTERI------PVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQK 1368
S A KA P +VT ++ P K + + + +S EE G E+ P G Q
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE-GSESEEEAPAGTRSQV 291
Query: 1369 KPEMADFRQQEAVCPWESQDGKGLSPQP----APDASDRSRGSSEAAGSVETRVAEVCLW 1424
K + + A P + GKG +P P AS G E + +
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEE 351
Query: 1425 EVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGP------GGTEEHFSK 1478
E A + +A+ + GAA +E +G K GP G E S+
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
Query: 1479 AAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEG 1538
++++ + E P + S G PQ A K SP++ + T P
Sbjct: 412 SSSEESDSEEEAPAQAKPS-GKAPQVRAASAPAKESPRKGAAPAPPRK-------TGPAA 463
Query: 1539 NKIK-GTMADICPGEETGVPSEESGLLALTATRREFFPTAPE-KPLCLLVHGPL 1590
+++ G + S+ L A+ A + + +P+ KP + GPL
Sbjct: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517
Score = 61.2 bits (147), Expect = 8e-09
Identities = 267/1302 (20%), Positives = 442/1302 (33%), Gaps = 251/1302 (19%)
Query: 349 AGENEMDAEDAHHQREANDVDEDRPKIFP-----------------------KSHSLKAP 385
AG+ + +ED + DV E +P + P K +
Sbjct: 193 AGQADSSSEDTSSSSDETDV-EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ 251
Query: 386 VQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNS-------------------GTA 426
V+ G++ A K S S+ ES EE+P G S GT
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP 311
Query: 427 GE--------SMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQRE 478
G+ GA + + G+P+ S+ S +ES +++ ++ L +
Sbjct: 312 GKGATPAPPGKAGAVASQTKAGKPEEDSE------SSSEESSDSEEETPAAKALLQAKAS 365
Query: 479 GSREQEDRGRRMTQGLGERKAERA--GKTGLAMLRQVS--RDKNIKQSKETPVGWQELPK 534
G Q + + A A GKTG A+ + + R+++ + S E +E P
Sbjct: 366 GKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425
Query: 535 AGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQ 594
S + R A + ++ A P +T A + + +Q+ DS+
Sbjct: 426 QAKPSGKAPQVRAA--------SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE-DSR 476
Query: 595 KKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKS 654
E+ E + + + KP + + V P + G L G+ P PG++
Sbjct: 477 SSSEESDSDREALAAMNAAQVKP---LGKSPQVKPASTMGMGPLGKGAGPVPPGKV---G 530
Query: 655 EAGDSVEARKVEKPGWEAAGPEAHTPD---ITKAEPCPWEASEGGEDGKPAQEAVKDLPQ 711
A S + K E+ ++ + + D T P ++ KP K PQ
Sbjct: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
Query: 712 EKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCL 771
+ A K +KP + ES ES+D SA S +AP + +
Sbjct: 591 KAGPV--AVQVKAEKPMDNSES--SEESSD----SADSEEAPAAMTAA------------ 630
Query: 772 WEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKA-SRKGSFGEMGEQTVK 830
+A A I + + CP + + ++ + G ++ ++ A S GS + T +
Sbjct: 631 -QAKPALKIPQTKACP-KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 688
Query: 831 AVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQ 890
+ S +ES E T G + S G Q +A V + L
Sbjct: 689 PAEDSSSSEESDSEEEKT--GLAVTVGQAKSVGKGLQV------KAASVPVKGSLGQGTA 740
Query: 891 EATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMPG-----KSEIEDVTAWEKP 945
P KT +V +E+ S+ E + D E+ K+ ++ A P
Sbjct: 741 PVLPGKTGPTVTQVKAEKQEDSESS------EEESDSEEAAASPAQVKTSVKKTQAKANP 794
Query: 946 ---EGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEE 1002
K P + V + + Q P + P Q S + A + P +
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV-PSVGKA 853
Query: 1003 NLTAGKAEICPWEVGAGAGEERALGAE-----AIRKSPNDTGKVSADLGPRERAVTAPEK 1057
TA +A+ P E +G+ EE + E A K T ++ A L P A +P K
Sbjct: 854 VATAAQAQTGP-EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP---AKESPRK 909
Query: 1058 PQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEV--------- 1108
PTP G GP A G D G + +E D G P V
Sbjct: 910 GAAPTPP-------GKTGPSAA--QAGKQDDSGSSS--EESDSDGEAPAAVTSAQVIKPP 958
Query: 1109 ---------------CPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKA 1153
P +AQ A+T KA+ + +T + ++ E +
Sbjct: 959 LIFVDPNRSPAGPAATPAQAQAASTPRKAR------ASESTARSSSSESEDEDVIPATQC 1012
Query: 1154 LEKGRLTSLGE--------DVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSM 1205
L G T++ MA +E+ I + K +E P A ++ ++
Sbjct: 1013 LTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKK-QEGP--ATQVDSAVGTL 1069
Query: 1206 SSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAP--------AADTEEFTTEDGE-- 1255
+ + S++A LR+ PK PE KAP ++D+ + EDGE
Sbjct: 1070 PATSPQSTSVQAKGTNKLRK-PK---LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP 1125
Query: 1256 ---KTSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVS---------TGGRAAD 1303
K++H L P T + + D A SQ L+S +A+
Sbjct: 1126 QGAKSAHTLVGPTPSRTETLVEETA--AESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1183
Query: 1304 VCPW-----DVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEK 1358
P V K D K E P + + K ++ G + +K R P+K
Sbjct: 1184 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASG-TTPQKSRKPKK 1242
Query: 1359 SEPKGVPVQKKPEMADFRQQEAVC------PWESQDGK----------GLSPQPAPDASD 1402
P+ + Q + PW + + L Q D
Sbjct: 1243 G-------AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVD 1295
Query: 1403 RSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEM 1462
++ SS R S KK ++ E GG A ++ + +G+
Sbjct: 1296 TTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE--GGEASVSPEKTSTTSKGKA 1353
Query: 1463 FLQKAGPGGTEEHFSKAA-----AKPREQEAVCPGEGTGSGG 1499
KA G +E K + AK +E + G GT GG
Sbjct: 1354 KRDKAS-GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1394
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 62.0 bits (149), Expect = 5e-09
Identities = 95/414 (22%), Positives = 153/414 (36%), Gaps = 33/414 (7%)
Query: 1199 SDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTS 1258
+DLPSSM E A+ + +A + G+ P TG ++ K+P E +
Sbjct: 115 ADLPSSMK-EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
Query: 1259 HELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSD 1318
E SV + A VS + +SS G+ + V P V + V +
Sbjct: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS-VKPAQVKASSVSTKE 232
Query: 1319 SSA-KAETCPW---EVTERI------PVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQK 1368
S A KA P +VT ++ P K + + + +S EE G E+ P G Q
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE-GSESEEEAPAGTRSQV 291
Query: 1369 KPEMADFRQQEAVCPWESQDGKGLSPQP----APDASDRSRGSSEAAGSVETRVAEVCLW 1424
K + + A P + GKG +P P AS G E + +
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEE 351
Query: 1425 EVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGP------GGTEEHFSK 1478
E A + +A+ + GAA +E +G K GP G E S+
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
Query: 1479 AAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEG 1538
++++ + E P + S G PQ A K SP++ + T P
Sbjct: 412 SSSEESDSEEEAPAQAKPS-GKAPQVRAASAPAKESPRKGAAPAPPRK-------TGPAA 463
Query: 1539 NKIK-GTMADICPGEETGVPSEESGLLALTATRREFFPTAPE-KPLCLLVHGPL 1590
+++ G + S+ L A+ A + + +P+ KP + GPL
Sbjct: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517
Score = 52.8 bits (125), Expect = 3e-06
Identities = 175/831 (21%), Positives = 290/831 (34%), Gaps = 145/831 (17%)
Query: 349 AGENEMDAEDAHHQREANDVDEDRPKIFP-----------------------KSHSLKAP 385
AG+ + +ED + DV E +P + P K +
Sbjct: 193 AGQADSSSEDTSSSSDETDV-EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ 251
Query: 386 VQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNS-------------------GTA 426
V+ G++ A K S S+ ES EE+P G S GT
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP 311
Query: 427 GE--------SMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQRE 478
G+ GA + + G+P+ S+ S +ES +++ ++ L +
Sbjct: 312 GKGATPAPPGKAGAVASQTKAGKPEEDSE------SSSEESSDSEEETPAAKALLQAKAS 365
Query: 479 GSREQEDRGRRMTQGLGERKAERA--GKTGLAMLRQVS--RDKNIKQSKETPVGWQELPK 534
G Q + + A A GKTG A+ + + R+++ + S E +E P
Sbjct: 366 GKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425
Query: 535 AGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQ 594
S + R A + ++ A P +T A + + +Q+ DS+
Sbjct: 426 QAKPSGKAPQVRAA--------SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE-DSR 476
Query: 595 KKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKS 654
E+ E + + + KP + + V P + G L G+ P PG++
Sbjct: 477 SSSEESDSDREALAAMNAAQVKP---LGKSPQVKPASTMGMGPLGKGAGPVPPGKV---G 530
Query: 655 EAGDSVEARKVEKPGWEAAGPEAHTPD---ITKAEPCPWEASEGGEDGKPAQEAVKDLPQ 711
A S + K E+ ++ + + D T P ++ KP K PQ
Sbjct: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
Query: 712 EKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCL 771
+ A K +KP + ES ES+D SA S +AP + +
Sbjct: 591 KAGPV--AVQVKAEKPMDNSES--SEESSD----SADSEEAPAAMTAA------------ 630
Query: 772 WEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKA-SRKGSFGEMGEQTVK 830
+A A I + + CP + + ++ + G ++ ++ A S GS + T +
Sbjct: 631 -QAKPALKIPQTKACP-KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 688
Query: 831 AVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQ 890
+ S +ES E T G + S G Q +A V + L
Sbjct: 689 PAEDSSSSEESDSEEEKT--GLAVTVGQAKSVGKGLQV------KAASVPVKGSLGQGTA 740
Query: 891 EATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMPG-----KSEIEDVTAWEKP 945
P KT +V +E+ S+ E + D E+ K+ ++ A P
Sbjct: 741 PVLPGKTGPTVTQVKAEKQEDSESS------EEESDSEEAAASPAQVKTSVKKTQAKANP 794
Query: 946 ---EGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEE 1002
K P + V + + Q P + P Q S + A + P +
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV-PSVGKA 853
Query: 1003 NLTAGKAEICPWEVGAGAGEERALGAE-----AIRKSPNDTGKVSADLGPRERAVTAPEK 1057
TA +A+ P E +G+ EE + E A K T ++ A L P A +P K
Sbjct: 854 VATAAQAQTGP-EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP---AKESPRK 909
Query: 1058 PQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEV 1108
PTP G GP A G D G + +E D G P V
Sbjct: 910 GAAPTPP-------GKTGPSAA--QAGKQDDSGSSS--EESDSDGEAPAAV 949
Score = 46.2 bits (108), Expect = 3e-04
Identities = 198/1022 (19%), Positives = 340/1022 (33%), Gaps = 174/1022 (17%)
Query: 738 ESTDFRG-PSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMG 796
+ TD G PS Q SS + + A + GD K P
Sbjct: 208 DETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPE 267
Query: 797 QEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPC 856
+E S G ES +E +R VKA +K+ Q + + P + T ++P
Sbjct: 268 EESESSEEGSESEEEAPAGTRS---------QVKASEKILQVRAASAPAKGTPGKGATPA 318
Query: 857 LDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQ 916
+ SQ ++ +E +++E TPA + + + +T + ++
Sbjct: 319 PPGKAGAVASQTKAGKPEEDSESSSEES--SDSEEETPAAKALLQAKASGKTSQVGAASA 376
Query: 917 VPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTE 976
+ + PGK+ A K + +++++ E D +P +
Sbjct: 377 PAKESPRKGAAPAPPGKTG----PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432
Query: 977 RPQTLLQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGA-----GEERALGAEAI 1031
PQ +AA +E+ G A P + G A G++ +
Sbjct: 433 APQV----------RAASA---PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
Query: 1032 RKSPNDTGKVSA-------DLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPG 1084
+S +D ++A LG + A P + P G VGP S G
Sbjct: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
Query: 1085 TLDADGPKAGFQELDHM-GCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAG 1143
+ D + + D G P V P + + +AK + KG QKAG
Sbjct: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK------PTSSPAKGPPQKAG 593
Query: 1144 SESAEQR-EKAL---EKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKIS 1199
+ + + EK + E +S D + A + Q + + ++ A K +
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTN 649
Query: 1200 DLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSH 1259
S+ + V G +A K P GS P + PA D+ D E+
Sbjct: 650 TTASAKVAPVRVG--TQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 1260 EL----------------------------QSVCPWETTAPADSVSHLDRQRPDQPKASS 1291
L Q P +V+ + ++ + ++S
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
Query: 1292 QRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIP-VKGVSRQDGK--GDS 1348
+ S A+ A V S +A+ P R P KG GK +
Sbjct: 767 EESDSEEAAASP--------AQVKTSVKKTQAKANP--AAARAPSAKGTISAPGKVVTAA 816
Query: 1349 QEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPW---------ESQDGK---GLSPQP 1396
+ K R+P K +P PV+ + A P ++Q G S +
Sbjct: 817 AQAKQRSPSKVKP---PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 873
Query: 1397 APDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQE--- 1453
D+ + + ++ S +T L E+P A P + G AA+ G+Q+
Sbjct: 874 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG 933
Query: 1454 ---RESQGQGE---------------MFL----QKAGPGGTEEHFSKAAAKPR-----EQ 1486
ES GE +F+ AGP T ++AA+ PR E
Sbjct: 934 SSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ-AQAASTPRKARASES 992
Query: 1487 EAVCPGEGTGSGGLLPQSGALDPELKVS--------PKEAGSMGSRMAELCQWEITDPEG 1538
A + ++P + L P ++ + P+ A A + +G
Sbjct: 993 TARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDG 1052
Query: 1539 NKIKGTMADICPGEETGVPSEESGLLALTATRREFFPTAPEKPLCLLVHGPLDHFFPESK 1598
K +G + +P ++ L L E P P+ P S
Sbjct: 1053 KKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQP-------------PVARTQPSSG 1099
Query: 1599 I-----PCPKVSRPASTFTLEGVRELQGPSGLE-PRTSLAPEPS-LQEAESQSSSLTEDS 1651
+ P S +++ +G +L+ P E + + APE S E S SSS +E+
Sbjct: 1100 VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEED 1159
Query: 1652 GQ 1653
G+
Sbjct: 1160 GE 1161
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 62.0 bits (149), Expect = 5e-09
Identities = 95/414 (22%), Positives = 153/414 (36%), Gaps = 33/414 (7%)
Query: 1199 SDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTS 1258
+DLPSSM E A+ + +A + G+ P TG ++ K+P E +
Sbjct: 115 ADLPSSMK-EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
Query: 1259 HELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSD 1318
E SV + A VS + +SS G+ + V P V + V +
Sbjct: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS-VKPAQVKASSVSTKE 232
Query: 1319 SSA-KAETCPW---EVTERI------PVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQK 1368
S A KA P +VT ++ P K + + + +S EE G E+ P G Q
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE-GSESEEEAPAGTRSQV 291
Query: 1369 KPEMADFRQQEAVCPWESQDGKGLSPQP----APDASDRSRGSSEAAGSVETRVAEVCLW 1424
K + + A P + GKG +P P AS G E + +
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEE 351
Query: 1425 EVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGP------GGTEEHFSK 1478
E A + +A+ + GAA +E +G K GP G E S+
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
Query: 1479 AAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEG 1538
++++ + E P + S G PQ A K SP++ + T P
Sbjct: 412 SSSEESDSEEEAPAQAKPS-GKAPQVRAASAPAKESPRKGAAPAPPRK-------TGPAA 463
Query: 1539 NKIK-GTMADICPGEETGVPSEESGLLALTATRREFFPTAPE-KPLCLLVHGPL 1590
+++ G + S+ L A+ A + + +P+ KP + GPL
Sbjct: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517
Score = 57.8 bits (138), Expect = 9e-08
Identities = 266/1302 (20%), Positives = 442/1302 (33%), Gaps = 252/1302 (19%)
Query: 349 AGENEMDAEDAHHQREANDVDEDRPKIFP-----------------------KSHSLKAP 385
AG+ + +ED + DV E +P + P K +
Sbjct: 193 AGQADSSSEDTSSSSDETDV-EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ 251
Query: 386 VQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNS-------------------GTA 426
V+ G++ A K S S+ ES EE+P G S GT
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP 311
Query: 427 GE--------SMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQRE 478
G+ GA + + G+P+ S+ S +ES +++ ++ L +
Sbjct: 312 GKGATPAPPGKAGAVASQTKAGKPEEDSE------SSSEESSDSEEETPAAKALLQAKAS 365
Query: 479 GSREQEDRGRRMTQGLGERKAERA--GKTGLAMLRQVS--RDKNIKQSKETPVGWQELPK 534
G Q + + A A GKTG A+ + + R+++ + S E +E P
Sbjct: 366 GKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425
Query: 535 AGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQ 594
S + R A + ++ A P +T A + + +Q+ DS+
Sbjct: 426 QAKPSGKAPQVRAA--------SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE-DSR 476
Query: 595 KKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKS 654
E+ E + + + KP + + V P + G L G+ P PG++
Sbjct: 477 SSSEESDSDREALAAMNAAQVKP---LGKSPQVKPASTMGMGPLGKGAGPVPPGKV---G 530
Query: 655 EAGDSVEARKVEKPGWEAAGPEAHTPD---ITKAEPCPWEASEGGEDGKPAQEAVKDLPQ 711
A S + K E+ ++ + + D T P ++ KP K PQ
Sbjct: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
Query: 712 EKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCL 771
+ A K +KP + ES ES+D SA S +AP + +
Sbjct: 591 KAGPV--AVQVKAEKPMDNSES--SEESSD----SADSEEAPAAMTAA------------ 630
Query: 772 WEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKA-SRKGSFGEMGEQTVK 830
+A A I + + CP + + ++ + G ++ ++ A S GS + T +
Sbjct: 631 -QAKPALKIPQTKACP-KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 688
Query: 831 AVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQ 890
+ S +ES E T G + S G Q +A V + L
Sbjct: 689 PAEDSSSSEESDSEEEKT--GLAVTVGQAKSVGKGLQV------KAASVPVKGSLGQGTA 740
Query: 891 EATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMPG-----KSEIEDVTAWEKP 945
P KT +V +E+ S+ E + D E+ K+ ++ A P
Sbjct: 741 PVLPGKTGPTVTQVKAEKQEDSESS------EEESDSEEAAASPAQVKTSVKKTQAKANP 794
Query: 946 ---EGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEE 1002
K P + V + + Q P + P Q S + A + P +
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV-PSVGKA 853
Query: 1003 NLTAGKAEICPWEVGAGAGEERALGAE-----AIRKSPNDTGKVSADLGPRERAVTAPEK 1057
TA +A+ P E +G+ EE + E A K T ++ A L P A +P K
Sbjct: 854 VATAAQAQTGP-EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP---AKESPRK 909
Query: 1058 PQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEV--------- 1108
PTP G GP A G D G + +E D G P V
Sbjct: 910 GAAPTPP-------GKTGPSAA--QAGKQDDSGSSS--EESDSDGEAPAAVTSAQVIKPP 958
Query: 1109 ---------------CPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKA 1153
P +AQ A+T KA+ + +T + ++ E +
Sbjct: 959 LIFVDPNRSPAGPAATPAQAQAASTPRKAR------ASESTARSSSSESEDEDVIPATQC 1012
Query: 1154 LEKGRLTSLGE--------DVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSM 1205
L G T++ MA +E+ I + K +E P A ++ ++
Sbjct: 1013 LTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKK-QEGP--ATQVDSAVGTL 1069
Query: 1206 SSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAP--------AADTEEFTTEDGE-- 1255
+ + S++A LR+ PK PE KAP ++D+ + EDGE
Sbjct: 1070 PATSPQSTSVQAKGTNKLRK-PK---LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP 1125
Query: 1256 ---KTSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVS---------TGGRAAD 1303
K++H L T ++ + D A SQ L+S +A+
Sbjct: 1126 QGAKSAHTLGPTPSRTETLVEETAA---ESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1182
Query: 1304 VCPW-----DVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEK 1358
P V K D K E P + + K ++ G + +K R P+K
Sbjct: 1183 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASG-TTPQKSRKPKK 1241
Query: 1359 SEPKGVPVQKKPEMADFRQQEAVC------PWESQDGK----------GLSPQPAPDASD 1402
P+ + Q + PW + + L Q D
Sbjct: 1242 G-------AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVD 1294
Query: 1403 RSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEM 1462
++ SS R S KK ++ E GG A ++ + +G+
Sbjct: 1295 TTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE--GGEASVSPEKTSTTSKGKA 1352
Query: 1463 FLQKAGPGGTEEHFSKAA-----AKPREQEAVCPGEGTGSGG 1499
KA G +E K + AK +E + G GT GG
Sbjct: 1353 KRDKAS-GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1393
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 62.0 bits (149), Expect = 5e-09
Identities = 95/414 (22%), Positives = 153/414 (36%), Gaps = 33/414 (7%)
Query: 1199 SDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTS 1258
+DLPSSM E A+ + +A + G+ P TG ++ K+P E +
Sbjct: 115 ADLPSSMK-EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
Query: 1259 HELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSD 1318
E SV + A VS + +SS G+ + V P V + V +
Sbjct: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS-VKPAQVKASSVSTKE 232
Query: 1319 SSA-KAETCPW---EVTERI------PVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQK 1368
S A KA P +VT ++ P K + + + +S EE G E+ P G Q
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE-GSESEEEAPAGTRSQV 291
Query: 1369 KPEMADFRQQEAVCPWESQDGKGLSPQP----APDASDRSRGSSEAAGSVETRVAEVCLW 1424
K + + A P + GKG +P P AS G E + +
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEE 351
Query: 1425 EVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGP------GGTEEHFSK 1478
E A + +A+ + GAA +E +G K GP G E S+
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
Query: 1479 AAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEG 1538
++++ + E P + S G PQ A K SP++ + T P
Sbjct: 412 SSSEESDSEEEAPAQAKPS-GKAPQVRAASAPAKESPRKGAAPAPPRK-------TGPAA 463
Query: 1539 NKIK-GTMADICPGEETGVPSEESGLLALTATRREFFPTAPE-KPLCLLVHGPL 1590
+++ G + S+ L A+ A + + +P+ KP + GPL
Sbjct: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517
Score = 55.5 bits (132), Expect = 4e-07
Identities = 177/840 (21%), Positives = 295/840 (35%), Gaps = 145/840 (17%)
Query: 349 AGENEMDAEDAHHQREANDVDEDRPKIFP-----------------------KSHSLKAP 385
AG+ + +ED + DV E +P + P K +
Sbjct: 193 AGQADSSSEDTSSSSDETDV-EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ 251
Query: 386 VQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNS-------------------GTA 426
V+ G++ A K S S+ ES EE+P G S GT
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP 311
Query: 427 GE--------SMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQRE 478
G+ GA + + G+P+ S+ S +ES +++ ++ L +
Sbjct: 312 GKGATPAPPGKAGAVASQTKAGKPEEDSE------SSSEESSDSEEETPAAKALLQAKAS 365
Query: 479 GSREQEDRGRRMTQGLGERKAERA--GKTGLAMLRQVS--RDKNIKQSKETPVGWQELPK 534
G Q + + A A GKTG A+ + + R+++ + S E +E P
Sbjct: 366 GKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425
Query: 535 AGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQ 594
S + R A + ++ A P +T A + + +Q+ DS+
Sbjct: 426 QAKPSGKAPQVRAA--------SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE-DSR 476
Query: 595 KKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKS 654
E+ E + + + KP + + V P + G L G+ P PG++
Sbjct: 477 SSSEESDSDREALAAMNAAQVKP---LGKSPQVKPASTMGMGPLGKGAGPVPPGKV---G 530
Query: 655 EAGDSVEARKVEKPGWEAAGPEAHTPD---ITKAEPCPWEASEGGEDGKPAQEAVKDLPQ 711
A S + K E+ ++ + + D T P ++ KP K PQ
Sbjct: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
Query: 712 EKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCL 771
+ A K +KP + ES ES+D SA S +AP + +
Sbjct: 591 KAGPV--AVQVKAEKPMDNSES--SEESSD----SADSEEAPAAMTAA------------ 630
Query: 772 WEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKA-SRKGSFGEMGEQTVK 830
+A A I + + CP + + ++ + G ++ ++ A S GS + T +
Sbjct: 631 -QAKPALKIPQTKACP-KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 688
Query: 831 AVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQ 890
+ S +ES E T G + S G Q +A V + L
Sbjct: 689 PAEDSSSSEESDSEEEKT--GLAVTVGQAKSVGKGLQV------KAASVPVKGSLGQGTA 740
Query: 891 EATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMPG-----KSEIEDVTAWEKP 945
P KT +V +E+ S+ E + D E+ K+ ++ A P
Sbjct: 741 PVLPGKTGPTVTQVKAEKQEDSESS------EEESDSEEAAASPAQVKTSVKKTQAKANP 794
Query: 946 ---EGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEE 1002
K P + V + + Q P + P Q S + A + P +
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV-PSVGKA 853
Query: 1003 NLTAGKAEICPWEVGAGAGEERALGAE-----AIRKSPNDTGKVSADLGPRERAVTAPEK 1057
TA +A+ P E +G+ EE + E A K T ++ A L P A +P K
Sbjct: 854 VATAAQAQTGP-EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP---AKESPRK 909
Query: 1058 PQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAA 1117
PTP G GP A G D G + +E D G P V + QE++
Sbjct: 910 GAAPTPP-------GKTGPSAA--QAGKQDDSGSSS--EESDSDGEAPAAVTSAQDQESS 958
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 60.1 bits (144), Expect = 2e-08
Identities = 254/1255 (20%), Positives = 406/1255 (32%), Gaps = 262/1255 (20%)
Query: 404 SRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQ 463
+ +T +E+ +EE+ EG T GE + + + + ++ + + KE+
Sbjct: 1293 AENTVQEEVQLEETKEG----TEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEG 1348
Query: 464 QNAHTSRMLQVCQREGSREQED---------------RGRRMTQGLGERKAERAGKTGLA 508
Q +++ ++ + G QE+ +G + +GL E G
Sbjct: 1349 QQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQ 1408
Query: 509 MLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNK 568
L + S ++ PV +E +A AE CP E TE T P
Sbjct: 1409 ELSEASSPDGKGSQEDDPVQEEEAGRASAS---------AEPCPAEGTEEPTEPP----- 1454
Query: 569 AEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVC 628
S DP S+++ G + P + K P + QE
Sbjct: 1455 --------------SHLSETDPSASERQSGS--------QLEPGLEKPPGATMMGQEHT- 1491
Query: 629 PWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPC 688
++ G + S+ D SV +K EK AH
Sbjct: 1492 --QAQPTQGAAERSSSVACSAALDCDPIWVSVLLKKTEKAFL------AHLASAVAELRA 1543
Query: 689 PWEASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAV 748
W + + A E +D+ Q Q + K K Q G + P E+ G +
Sbjct: 1544 RWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQGRAGRMVLEPPREA--LTGELLL 1601
Query: 749 SIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRES 808
Q Q+ + + + L LG +
Sbjct: 1602 QTQ-----------------------------QRRHRLRGLRNLSAFSERTLGLGPLSFT 1632
Query: 809 LQEKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQF 868
L++ E A ++GE+ + E CP E+ V SP + ++ ++
Sbjct: 1633 LED-EPALSTALGSQLGEEA---------EGEEFCPCEACVRKKVSP-MSPKATMGATRG 1681
Query: 869 LCNGGSRATQVCPQ---EDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQK 925
Q+ + E EA E P KT P TS + +G E
Sbjct: 1682 PIKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDP-----------TSTRTVQGAEGGL 1730
Query: 926 DKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMS 985
PG S+ V E EG + P G Q R T +T
Sbjct: 1731 G----PGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSET----- 1781
Query: 986 GSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADL 1045
S GS+ + + E + + E G G+G E L EA D G+
Sbjct: 1782 -SAGSELGEA---EQEGEGISERGETG----GQGSGHEDNLQGEAAAGGDQDPGQSDGAE 1833
Query: 1046 GPRERAVTAPEKPQKPTPEWE-VACPW--GSVGPGACSQHPGTLDADGPKAGFQELDHMG 1102
G + APE + PE E V P G P + D + P+A +
Sbjct: 1834 G-----IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESE 1888
Query: 1103 CRPGEVCPWEAQ------EAATSEKAKICPWEVSEGTTGKGLDQ--KAGSESAEQREKAL 1154
WE Q EA +EK E E +G D+ G+E+ E E A
Sbjct: 1889 DVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQ 1948
Query: 1155 EKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHS 1214
E T Q E+ I + E+ ++ + L + ++ AEG +
Sbjct: 1949 EAEGQT---------------QPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEA 1993
Query: 1215 ------LEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWE 1268
+EA E Q+ + + PE E P ++ EE +GE E
Sbjct: 1994 QPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTE-------- 2045
Query: 1269 TTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAET--- 1325
D+ D + + +Q A + D +++ A+ E+
Sbjct: 2046 ----GDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGV 2101
Query: 1326 -CPWEVTERIPVKGVSRQDGKGDSQEEKG--RAPE-----KSEPKGVPVQK-----KPEM 1372
P E +G+ + +G++Q E APE + E +GV Q +PE
Sbjct: 2102 EAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPES 2161
Query: 1373 ADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPSA 1432
QEA E + L AP+A ++ SE + E E VEAP A
Sbjct: 2162 EGIEAQEA----EEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEA 2217
Query: 1433 KKAEICPWEAGGGAAE-EGEQERESQG--QGEMFLQ---KAGPGGTEEHFSKAAAKPREQ 1486
++ E P G E EGE + ES+G QGE G G +EE ++ P ++
Sbjct: 2218 EE-EAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDR 2276
Query: 1487 EAVCPGEG----------------------------------------------TGSGGL 1500
P G TG+
Sbjct: 2277 PTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHA 2336
Query: 1501 LPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEGNKIKGTMADICPGEETG 1555
++ + PE S +E +GSR E E D + ++ G++A P E G
Sbjct: 2337 ERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQALGSLA---PTEAVG 2388
Score = 48.5 bits (114), Expect = 5e-05
Identities = 64/260 (24%), Positives = 102/260 (39%), Gaps = 24/260 (9%)
Query: 1316 KSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPV---QKKPEM 1372
+SD + E E + +GV + +GD+QE +G A +SE P + +PE
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887
Query: 1373 ADFRQQEAVCPWESQ-DGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPS 1431
D EA WE Q + +G AP+A ++ +E+ ++ET + E
Sbjct: 1888 EDVETPEA--EWEVQPESEGAE---APEAEKEAQPETESVEALETEGEDE---PESEGAE 1939
Query: 1432 AKKAEICPWEAGGGAAEEGE----QERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQE 1487
A++AE EA G E E QE E + Q E +A E ++ A+P ++
Sbjct: 1940 AQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESED 1999
Query: 1488 AVCPGEGTGSGGLLPQSGALDPE---LKVSPKEAGSMGSRMAELCQWEITD--PEGNKIK 1542
P G + PE ++ PK G + Q D PE + ++
Sbjct: 2000 VEAP---EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVE 2056
Query: 1543 GTMADICPGEETGVPSEESG 1562
A+ E G E G
Sbjct: 2057 APEAEEEAQEAEGEVQEAEG 2076
Score = 43.9 bits (102), Expect = 0.001
Identities = 102/478 (21%), Positives = 176/478 (36%), Gaps = 56/478 (11%)
Query: 350 GENEMDAEDAHHQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYR 409
GE + ++E D E + P+S ++AP +G +
Sbjct: 1842 GEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP---------------- 1885
Query: 410 EKESVEESPEGQNSGTAGESMGAPS-RSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHT 468
E E V E+PE + ES GA + + + +P+ S +A +D+ + +
Sbjct: 1886 ESEDV-ETPEAEWE-VQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEA 1943
Query: 469 SRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSK----E 524
Q + EG + E + E + E L + + + Q + E
Sbjct: 1944 EEAAQ--EAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVE 2001
Query: 525 TPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESR 584
P E+ +A ++ +D A+ E + + P APE+
Sbjct: 2002 APEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAE 2061
Query: 585 ALRQD-PGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPG-S 642
Q+ G+ Q+ GEA +SE +D ++ E E V E+ + G
Sbjct: 2062 EEAQEAEGEVQEAEGEAHPESEDVDA----QEAEGEAQPESEGVEAPEAEGEAQKAEGIE 2117
Query: 643 APQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPA 702
AP+ G + +SE ++ EA +P E+ G EA + +A+P SEG E A
Sbjct: 2118 APETEGEAQPESEGIEAPEAEGEAQP--ESEGVEAQDAE-GEAQP----ESEGIE----A 2166
Query: 703 QEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSL 762
QEA ++ E + E +P + E + E+ P ++AP + E +
Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQP--ESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE 2224
Query: 763 GSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGS 820
G+ E +A + E E G +SLG G + E+AS S
Sbjct: 2225 PEGV------ETPEAEGEAQPE-SEGETQGEKKGSPQVSLGDG-----QSEEASESSS 2270
Score = 43.1 bits (100), Expect = 0.002
Identities = 228/1062 (21%), Positives = 346/1062 (32%), Gaps = 223/1062 (20%)
Query: 568 KAEICPWETSEGA-PESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEA 626
+AE E SEG P S AL S + E +G+ + ++P L
Sbjct: 560 RAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGLS--- 616
Query: 627 VCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAE 686
C W+S G+ R +S A PG P H
Sbjct: 617 -CSWDSEGASSTPSTCTSSQQGQRRHRSRAS---AMSSPSSPGLGRVAPRGH-------- 664
Query: 687 PCPWEASEGGEDGKPAQEAV-KDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGP 745
P + + P +V K +P+ ++ R + G S S + R P
Sbjct: 665 --PRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPP 722
Query: 746 SAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTG 805
S+ S+ S + G+ + + + + A W D G S
Sbjct: 723 SSGSLP---SQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGD---AGSRTCSPAPI 776
Query: 806 RESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAG 865
+ S S GE T + L Q P + V H S C S+ G
Sbjct: 777 PPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGR--PEQGAVGPHRSHCC----SQPG 830
Query: 866 SQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQK 925
+Q QE R + EA+ CP PRG +
Sbjct: 831 TQ------------PAQEAQRGPSPEASWLCGRYCPTP--------------PRGRPCPQ 864
Query: 926 DKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMS 985
+ G + G + A GP S G+ P P P + S
Sbjct: 865 RRSSSCGST------------GSSHQSTARGPGGSPQEGTRQPGPTPSPGPNSGASRRSS 912
Query: 986 GSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADL 1045
S G+ + L E+ L +G G G+E A G SP+ + S +
Sbjct: 913 ASQGAGSRG---LSEEKTLRSG---------GGPQGQEEASGV-----SPSSLPRSSPEA 955
Query: 1046 GPRERAVTAPEKPQKPT----PEWEVACPWGSVGPGACSQHPGTLDADGP--KAGFQELD 1099
RE PE+P T E A G GP +L+ G +AG Q L+
Sbjct: 956 VVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQQSLE 1015
Query: 1100 HMGCRPGEVCPWEAQEAATSEKAK---------ICPWEVSEGTTGKGLDQKAGS------ 1144
PG+ E +S+ P VSE G D++A +
Sbjct: 1016 G---DPGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEAPAEAGADREAPAGCRVSL 1072
Query: 1145 -------ESAEQREKAL---EKGRLTSLGEDVSKGMAKL--CQQQETICIWENKDLRE-- 1190
++ Q +AL ++GR +S+ E VS+ MA+ C I + L E
Sbjct: 1073 RALPGRVSASTQIMRALMGSKQGRPSSVPE-VSRPMARRLSCSAGALITCLASLQLFEED 1131
Query: 1191 --SPAQAPKISDLPS-----SMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPA 1243
SPA + D P S+S ++ G D+ +D E + P
Sbjct: 1132 LGSPASKVRFKDSPRYQELLSISKDLWPGC--------DVGEDQLDSGLWELTWSQALPD 1183
Query: 1244 ----ADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQP-KASSQRLVSTG 1298
A TE FT S E++ P L Q + P K S+QR
Sbjct: 1184 LGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTSNQR----- 1238
Query: 1299 GRAADVCPWDVPDAGVYKS--DSSAKAETC-PWEVTERIPVKGVSRQDGKGDSQEEKGRA 1355
PD+ Y+S D + + C P + R + + + DS+E++ +
Sbjct: 1239 -----------PDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERDSEEQRASS 1287
Query: 1356 PEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVE 1415
+ + VQ++ ++ + + E +G+GL EA E
Sbjct: 1288 NLEQLAENT-VQEEVQLEETK--------EGTEGEGLQ--------------EEAVQLEE 1324
Query: 1416 TRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPGGTEEH 1475
T+ E E V+ K+ E GE ++E + Q E + G G EE
Sbjct: 1325 TKTEEGLQEEGVQLEETKETE-------------GEGQQEEEAQLEEIEETGGEGLQEEG 1371
Query: 1476 FSKAAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVS--PKEAGSMGSRMAELCQ--- 1530
K EG GGL Q AL+ LK P+E G ++E
Sbjct: 1372 VQLEEVK----------EGP-EGGL--QGEALEEGLKEEGLPEEGSVHGQELSEASSPDG 1418
Query: 1531 --WEITDPEGNKIKG---TMADICPGEETGVPSEESGLLALT 1567
+ DP + G A+ CP E T P+E L+ T
Sbjct: 1419 KGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSET 1460
Score = 40.8 bits (94), Expect = 0.011
Identities = 110/491 (22%), Positives = 179/491 (36%), Gaps = 108/491 (21%)
Query: 290 PQSPNLLTYICPWE------NAELP-AKQENVPQ---------EGPSGPERGHHSPAPAR 333
P+S ++ T WE AE P A++E P+ EG PE A
Sbjct: 1885 PESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE 1944
Query: 334 ARLWRALSVAVEKSRAGENEMDAEDAHHQREANDVD---------EDRPKIFPKSHSLKA 384
A +S E++ E+A Q E+ DV+ E + P+S ++A
Sbjct: 1945 EAAQEAEGQTQPESEVIESQEAEEEA--QPESEDVEALEVEVETQEAEGEAQPESEDVEA 2002
Query: 385 PVQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKA 444
P +G M+ E + VE P+ + A E G ++ +P+
Sbjct: 2003 PEAEGEMQE---------AEEEAQPESDGVEAQPKSEGE-EAQEVEGETQKTEGDAQPE- 2051
Query: 445 VSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGK 504
SD E+ + ++ A + +V + EG E + GE + E G
Sbjct: 2052 ---------SDGVEAPEAEEEAQEAEG-EVQEAEGEAHPESEDVDAQEAEGEAQPESEG- 2100
Query: 505 TGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPD 564
E P+A + + AE TE E +
Sbjct: 2101 -------------------------VEAPEA------EGEAQKAEGIEAPETEGEAQPES 2129
Query: 565 SGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQ 624
G +A P E PES + ++Q GEA+ +SE I+ ++ E E
Sbjct: 2130 EGIEA---PEAEGEAQPESEGV-----EAQDAEGEAQPESEGIEA----QEAEEEAQPEL 2177
Query: 625 EAV-CPWESADRGGLSPG-SAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDI 682
E V P + S G AP+ G + + E ++ EA + +P E G E TP+
Sbjct: 2178 EGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQP--EPEGVE--TPEA 2233
Query: 683 T-KAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKEQ-----KPGGDLESLCP 736
+A+P ++G + G P Q ++ D E+ + +++ PGGD P
Sbjct: 2234 EGEAQPESEGETQGEKKGSP-QVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRP 2292
Query: 737 WESTDFRGPSA 747
T GPS+
Sbjct: 2293 GSQT---GPSS 2300
Score = 39.7 bits (91), Expect = 0.025
Identities = 58/252 (23%), Positives = 97/252 (38%), Gaps = 33/252 (13%)
Query: 303 ENAELPAKQ-ENVPQ-EGPSGPE-RGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDA 359
E E P + E P+ EG PE G P A A +S E + E+A
Sbjct: 2114 EGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEA 2173
Query: 360 HHQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESPE 419
+ E + E + P+S ++AP +G + ++A E E VE +PE
Sbjct: 2174 QPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVE-TPE 2232
Query: 420 GQNSG-------TAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRML 472
+ T GE G+P S G+ + S+ ++ +P +D+ + T
Sbjct: 2233 AEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVP-EDRPTPPPSPGGDTPH-- 2289
Query: 473 QVCQREGSREQEDRGRRMTQG------------LGERKAERAGKTGLAML-RQVSR---D 516
QR GS+ R + G LG+ ++ A TG R+ +R +
Sbjct: 2290 ---QRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPE 2346
Query: 517 KNIKQSKETPVG 528
+ + +E P+G
Sbjct: 2347 SSTSEQEEAPLG 2358
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 53.1 bits (126), Expect = 2e-06
Identities = 100/478 (20%), Positives = 187/478 (39%), Gaps = 52/478 (10%)
Query: 273 PALAPTPAPALAPVPVSPQSPNLLTYICPWE-----NAELPAKQE-------NVPQEGPS 320
P A +PA A P +SP P E A+ PAK+E P++ S
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 321 GPERGHHSPAPARARLWR-ALSVAVEKSRAGENEMDAEDAHHQREANDVDEDRPKIFPKS 379
+ SPA A++ + A S A KS E+A +A +++ K K+
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 380 HSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEE---SPEGQNSGTAGESMGAPSRS 436
K+PV+ + ++S + K V+E SPE S E+ +P ++
Sbjct: 667 ---KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK-SPEKA 722
Query: 437 PRLGRPKAVSKQAALIP-SDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLG 495
+ +A + + A P ++ +S + ++ ++ L V E ++ R
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP 782
Query: 496 ERKAE------RAGKTGLAMLRQVSR--DKNIKQSKE--TPVGWQELPKAGL--QSLGSA 543
E+ ++ + + L++ ++ +K I + +E +PV +E P+ + A
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 544 DHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGK 603
+ A P + ++++ ++ K P + P ++ +++K+ E + K
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Query: 604 SEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAP-QDPGRIRDKSEAGDSVEA 662
VP K+ V +E P E + P A ++P + +K EA +
Sbjct: 903 ------VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 663 RKVEK-------PGWEAAGPE-----AHTPDITKAEPCPWEASEGGEDGKPAQEAVKD 708
K EK P EA E + P KAE +S +D KP ++A +D
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 52.4 bits (124), Expect = 4e-06
Identities = 135/619 (21%), Positives = 234/619 (37%), Gaps = 105/619 (16%)
Query: 804 TGRESLQEKEKASRKGSFGEM-----GEQTVK---AVQKLSQQQESVCP--RESTVPGHS 853
T E + KE+ ++ GE GE+ K A + S ++E+ P E+ P +
Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEA 530
Query: 854 -SPCLDNSSSKAGSQFLCNGGSRATQVC--PQEDLRPEAQEATPAKTEICPWEVNERTRE 910
SP + + S A + S A + P E PE +EA P + +E
Sbjct: 531 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE 590
Query: 911 EWTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQP 970
E A+ P +S +K K P K E + + P K+EA P E P + P
Sbjct: 591 E---AKSPAEAKS-PEKAKSPVKEEAKSPAEAKSP----VKEEAKSPAEVKSPEK-AKSP 641
Query: 971 RPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEA 1030
++ + P+ KA + EE + KA+ P + A + E+ +A
Sbjct: 642 TKEEAKSPE-----------KAKS---PEKEEAKSPEKAK-SPVKAEAKSPEKAKSPVKA 686
Query: 1031 IRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADG 1090
KSP P + +PEK + P E +A
Sbjct: 687 EAKSPEKA------KSPVKEEAKSPEKAKSPVKE----------------------EAKS 718
Query: 1091 PKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQR 1150
P+ + P + +EA + EKAK K LD K S E +
Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK-------SPEKAKTLDVK----SPEAK 767
Query: 1151 EKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVA 1210
A E+ R + D AK ++E + K + A+AP+ E+
Sbjct: 768 TPAKEEARSPA---DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPE---------KEIP 815
Query: 1211 EGHSLEATEKGDLR-QDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWET 1269
+ +++ K + + Q+ K P+ +EKAPA E + ++ + + ++ P
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE 875
Query: 1270 TAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWE 1329
+V ++P + K +++ + + + P K D+ K +T E
Sbjct: 876 EKKEPAV-----EKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT---E 927
Query: 1330 VTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDG 1389
V ++ P +++ K E+K APEK + K KKPE + +A +D
Sbjct: 928 VAKKEPDDAKAKEPSK--PAEKKEAAPEKKDTKEEKA-KKPEEKPKTEAKA-----KEDD 979
Query: 1390 KGLSPQPAPDASDRSRGSS 1408
K LS +P+ ++++ SS
Sbjct: 980 KTLSKEPSKPKAEKAEKSS 998
Score = 48.1 bits (113), Expect = 7e-05
Identities = 81/382 (21%), Positives = 152/382 (39%), Gaps = 39/382 (10%)
Query: 1113 AQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAK 1172
A+EAA+ EK P + + + + + K+ EK + + E S AK
Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 1173 LCQQQETICIWENK--DLRESPAQ----APKISDLPSSMSSEVAEGHSLEATEKGDLRQD 1226
+++E E K + +SPA+ +P + P S V E A K ++++
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEE 625
Query: 1227 PKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQ 1286
K+ + E + EKA + EE + + K+ + ++ P + +P + + + P++
Sbjct: 626 AKSPA--EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA----EAKSPEK 679
Query: 1287 PKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKG 1346
K+ + + +A P KS AK+ PVK ++ K
Sbjct: 680 AKSPVKAEAKSPEKAKS------PVKEEAKSPEKAKS-----------PVKEEAKSPEKA 722
Query: 1347 DSQ-EEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSR 1405
S +E+ + PEK++ K PE A ++ +S + K + + A +D+
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP 782
Query: 1406 GSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQ 1465
+++ E + E + E A + EI E +E E+ +E +
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK-------V 835
Query: 1466 KAGPGGTEEHFSKAAAKPREQE 1487
K P EE KA A P+ +E
Sbjct: 836 KEPPKKAEE--EKAPATPKTEE 855
Score = 35.0 bits (79), Expect = 0.61
Identities = 61/252 (24%), Positives = 96/252 (38%), Gaps = 26/252 (10%)
Query: 1415 ETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPGGTEE 1474
ET+V E E E AK+ E G EEG +E E++G E K+ P
Sbjct: 463 ETQVTEEVTEE--EEKEAKEEE--------GKEEEGGEEEEAEGGEEE--TKSPPAEEAA 510
Query: 1475 HFSKAAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQWEIT 1534
K A P ++EA P E + A P SP++A S A+ E
Sbjct: 511 SPEKEAKSPVKEEAKSPAEAKSP----EKEEAKSPAEVKSPEKAKSPAKEEAK-SPPEAK 565
Query: 1535 DPEGNKIKGTMADICPGEETGVPSEESGLLALTATRREFFPTAPEKPLCLLVHGPLDHFF 1594
PE + K + A++ E+ P++E A P + P+ P +
Sbjct: 566 SPEKEEAK-SPAEVKSPEKAKSPAKEEAKSPAEAKS----PEKAKSPVKEEAKSPAEAKS 620
Query: 1595 P---ESKIPCP-KVSRPASTFTLEGVRELQGPSGLEPRTSLAPEPSLQEAESQSSSLTED 1650
P E+K P K A + T E + + E + +PE + ++++ S +
Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680
Query: 1651 SGQVAFEAQYEE 1662
V EA+ E
Sbjct: 681 KSPVKAEAKSPE 692
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 51.6 bits (122), Expect = 6e-06
Identities = 118/495 (23%), Positives = 191/495 (38%), Gaps = 62/495 (12%)
Query: 675 PEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKATF-WKEQKPGGDLES 733
PE P T P E ++G + P ++ +++ P E + + TF E++ L S
Sbjct: 843 PETQAPLWT-----PEEINQGAMN--PLEKEIQE-PLESVEVNQETFRLLEEENQESLRS 894
Query: 734 LCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCL--WEAGDAPAIQKAEICPWE-- 789
L W + R P V ++ + E +LG G + L E Q A++ WE
Sbjct: 895 LGAWNLENLRSPEEVDKESQRNLEEEENLGKGEYQESLRSLEEEGQELPQSADVQRWEDT 954
Query: 790 -LDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCP---- 844
D + QE G E+ E E R+ G G++ V +L+ +E P
Sbjct: 955 VEKDQELAQESPPGMAGVENEDEAELNLREQD-GFTGKEEVVEQGELNATEEVWIPGEGH 1013
Query: 845 RESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQV------CPQEDLRPEAQEATPAKTE 898
ES P ++ +S K G++ L + ++ QV PQ PEA E + +
Sbjct: 1014 PESPEPKEQRGLVEGASVKGGAEGLQDPEGQSQQVGAPGLQAPQG--LPEAIEPL-VEDD 1070
Query: 899 ICPWEVNERTREEWTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPW 958
+ P ++ E P GES E PG + V P G + ++E + P
Sbjct: 1071 VAPG--GDQASPEVMLGSEPAMGESAAGAEPGPG----QGVGGLGDP-GHLTREEVMEP- 1122
Query: 959 ESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADI--CPLDVEENLTAGKAEICPWEV 1016
++ S + R Q E P+ L+ +G +G++ +++ D E G+ E E
Sbjct: 1123 -PLEEESLEAK-RVQGLEGPRKDLEEAGGLGTEFSELPGKSRDPWEPPREGREES---EA 1177
Query: 1017 GAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGP 1076
A G E A AE + + +D LG E P P+P + P P
Sbjct: 1178 EAPRGAEEAFPAETLGHTGSDAPS-PWPLGSEEAEEDVPPVLVSPSPTY---TPILEDAP 1233
Query: 1077 GACSQHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGK 1136
G Q G+ +A G EA SE+ ++ E+ EG +
Sbjct: 1234 GPQPQAEGSQEASWGVQGRA---------------EALGKVESEQEELGSGEIPEGPQEE 1278
Query: 1137 GLDQKAGSESAEQRE 1151
G + + SE E E
Sbjct: 1279 GEESREESEEDELGE 1293
Score = 38.5 bits (88), Expect = 0.055
Identities = 104/459 (22%), Positives = 172/459 (37%), Gaps = 71/459 (15%)
Query: 999 DVEENLTAGKAEICP--WEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPE 1056
+V N A +AE C W A ER L A + G ++A R P
Sbjct: 108 EVARNRRAVEAEKCARAWLSSQVAELERELEALRVAHEEERVG-LNAQAACAPRCPAPPR 166
Query: 1057 KPQKPTPEWE-VACPWGSVGPGACSQHPGTLDADGPKAGFQE-LDHMGCRPGEVCPWEAQ 1114
P P PE E +A G GA G+QE + HM G+ +
Sbjct: 167 GPPAPAPEVEELARRLGEAWRGAVR-------------GYQERVAHMETSLGQARERLGR 213
Query: 1115 EAATSEKAKICPWEVSEGTTGKGLDQKAGSESA-----EQREKALEKGRLTSLG-EDVSK 1168
+ + ++ + + G L+++A E ++R +A EK +L E +
Sbjct: 214 AVQGAREGRL-ELQQLQAERGGLLERRAALEQRLEGRWQERLRATEKFQLAVEALEQEKQ 272
Query: 1169 GMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHSLEATEKGDLRQDPK 1228
G+ Q + + E + +++ L S+S EVA +L E L Q P
Sbjct: 273 GL-----QSQIAQVLEGRQ---------QLAHLKMSLSLEVATYRTLLEAENSRL-QTPG 317
Query: 1229 TGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPK 1288
GS Q+ P + + T +G + L + P T+ P+ + L+ P K
Sbjct: 318 GGSKTSLSFQD--PKLELQFPRTPEGRRLGSLLPVLSP--TSLPSPLPATLETPVPAFLK 373
Query: 1289 ASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDS 1348
T A+ P P A D+ +A+ P + + Q G+ +
Sbjct: 374 NQEFLQARTPTLASTPIP-PTPQAPSPAVDAEIRAQDAPLSLLQT--------QGGRKQA 424
Query: 1349 QEEKGRAPEKSEPK-GVP--VQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSR 1405
E P ++E + +P V PE ++QEA +D L+P +PD S
Sbjct: 425 PE-----PLRAEARVAIPASVLPGPEEPGGQRQEASTGQSPEDHASLAPPLSPDHSSLEA 479
Query: 1406 GSSEAAGSVETRVAEVC-------LWEVVEAPSAKKAEI 1437
E+ GS RV +C +W +VE +A + ++
Sbjct: 480 KDGESGGS---RVFSICRGEGEGQIWGLVEKETAIEGKV 515
Score = 32.0 bits (71), Expect = 5.2
Identities = 41/172 (23%), Positives = 69/172 (40%), Gaps = 13/172 (7%)
Query: 645 QDPGRIRDKSEAGDSVEARKVEKPG--WEAAGPEAHTPDITKAEPCPWEASEGGEDGKPA 702
++ GR D SE + + PG E A P P + +P W+ +G DG
Sbjct: 1357 EECGRDSDLSEEFEDLGTEAPFLPGVPGEVAEPLGQVPQLL-LDPAAWDR-DGESDGFAD 1414
Query: 703 QEAVKDLPQEKQKTRK---ATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECS 759
+E + +E Q+ + A W G L++L + +F +VS+ P
Sbjct: 1415 EEESGEEGEEDQEEGREPGAGRWGPGSSVGSLQALSSSQRGEFLESDSVSVSVPWDDSLR 1474
Query: 760 GSLGSGIAEVCLWEAGDA--PAIQKAEICP--WELDDNVMGQEMLSLGTGRE 807
G++ E+ D+ P+ + E P E +D V G L + +G E
Sbjct: 1475 GAVAGAPKTALETESQDSAEPSGSEEESDPVSLEREDKVPGP--LEIPSGME 1524
Score = 31.6 bits (70), Expect = 6.8
Identities = 48/217 (22%), Positives = 75/217 (34%), Gaps = 25/217 (11%)
Query: 1046 GPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCR- 1104
GP E E +PE S+ P H DG G + CR
Sbjct: 443 GPEEPGGQRQEASTGQSPE-----DHASLAPPLSPDHSSLEAKDGESGGSRVFSI--CRG 495
Query: 1105 PGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGE 1164
GE W E T+ + K+ E + L++K +S + LEK L SLGE
Sbjct: 496 EGEGQIWGLVEKETAIEGKVVSSLQQEIWEEEDLNRKEIQDS----QVPLEKETLKSLGE 551
Query: 1165 DVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHSLEATEKGDLR 1224
++ + + L Q EN+ + P S+ ++ SLE K L+
Sbjct: 552 EIQESLKTLENQSHETLERENQ-------------ECPRSLEEDLETLKSLEKENKELLK 598
Query: 1225 QDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHEL 1261
+ + P + T + +K + EL
Sbjct: 599 DVEVVRPLEKEAVGQLKPTGKEDTQTLQSLQKENQEL 635
>gi|112821681 G protein-regulated inducer of neurite outgrowth 1
[Homo sapiens]
Length = 1008
Score = 50.1 bits (118), Expect = 2e-05
Identities = 92/403 (22%), Positives = 139/403 (34%), Gaps = 60/403 (14%)
Query: 374 KIFPKSHSLKAPVQQG--SMRSLGLA--IKALTRSRSTYREKESVEESPEGQNSGTAGES 429
K+ P+S PV G RSLG A A+ +T + + + + +G
Sbjct: 478 KVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSS----EKAGLVASG 533
Query: 430 MGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRR 489
AP+ S + P AV K+ + S K + + +V G G+
Sbjct: 534 KAAPTASGK-AEPLAVGKEDPV--SKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKV 590
Query: 490 MTQGLGERKAERAGKTGLAMLRQVS------RDKNIKQSKETPVGWQELPKAGLQSLGSA 543
LG+ +A GK G L + S D + G + K Q +A
Sbjct: 591 DPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAA 650
Query: 544 DHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGK 603
VC + T + + D G+ + P + +G P S + D S+K + GK
Sbjct: 651 PGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLG-KADSAPSRKTESPSLGK 709
Query: 604 SEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEAR 663
P+ + + KP R+ + A SP A GR+ K+E S EA
Sbjct: 710 VVPLS---LEKTKPSSSSRQLD-----RKALGSARSPEGARGSEGRVEPKAEPVSSTEAS 761
Query: 664 KVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKATFWK 723
+ + EAAG E PCP A A P+ + KA W+
Sbjct: 762 SLGQKDLEAAGAE--------RSPCPEAA------------APPPGPRTRDNFTKAPSWE 801
Query: 724 EQKPGGDLE--------------SLCPWESTDFRGPSAVSIQA 752
P E ++ P D G SA S QA
Sbjct: 802 ASAPPPPREDAGTQAGAQACVSVAVSPMSPQDGAGGSAFSFQA 844
Score = 42.7 bits (99), Expect = 0.003
Identities = 210/914 (22%), Positives = 305/914 (33%), Gaps = 120/914 (13%)
Query: 552 PWEVTESETRQPDSGNKA--EICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPI-- 607
P ++E + D N E +++S+ A + ++DPG S+K GK+EP
Sbjct: 131 PVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEIL 190
Query: 608 ---DVVPMMRKKPERLVREQEA----VCPWESADRGGLSPGSAPQDPGRIRD----KSEA 656
D V R P + +E V P S+ +SP +DPG +R S+
Sbjct: 191 GKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRK--EDPGSLRKVDPVSSDK 248
Query: 657 GDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGK--PAQEAVKDLPQEKQ 714
D V RK E+P + + H K P E + GK P D P +
Sbjct: 249 VDPVFPRK-EEPRYSG---KEHPVSSEKVAPTSAEKVDLVLSGKRDPGPSGKAD-PMPLE 303
Query: 715 KTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWEA 774
A+ K + G L L P S GP + APGS LG + CL A
Sbjct: 304 SMDSASTGKTEP--GLLGKLIPGSSGK-NGPVSSGTGAPGS------LGR-LDPTCLGMA 353
Query: 775 GDAPAIQKAEICPWELDDNVMGQEM--LSLGTGRE----------------SLQEKEKAS 816
D ++ E P +D+ +M S G GR SL+ + S
Sbjct: 354 -DPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASAKTDLTSLKNVDPMS 412
Query: 817 RKG----SFGEMGEQTVKAVQKLSQQQE---SVCPRESTVPGHSSPCLDNSSSKAGSQFL 869
S G+M + LS Q SV + PG P +
Sbjct: 413 SGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISA--- 469
Query: 870 CNGGSRATQVCPQEDLRPEAQEATPAKTEIC--PWEVNERTREEWTSAQVPRGGESQKDK 927
GSR T E + PE+ T + P + A+ GG+
Sbjct: 470 ---GSRKTS---SEKVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLS 523
Query: 928 EKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQ-DTERPQTLLQMSG 986
+ G + A G+ + AVG + V G P Q D+ ++ G
Sbjct: 524 SEKAGL--VASGKAAPTASGKAEPL-AVGKEDPVSKGKADAGPSGQGDSVSIGKVVSTPG 580
Query: 987 S---VGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSA 1043
V S D L E + GK P E G+ +A + + P GK
Sbjct: 581 KTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAET 640
Query: 1044 DLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGC 1103
L P + AP + + E V PG+C + G + D
Sbjct: 641 KL-PGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAPS 699
Query: 1104 RPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLG 1163
R E + EK K ++ + LD+KA + +GR+
Sbjct: 700 RKTESPSLGKVVPLSLEKTK-------PSSSSRQLDRKALGSARSPEGARGSEGRVEPKA 752
Query: 1164 EDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGHSLEATEKGDL 1223
E VS A Q++ E SP + S EA+
Sbjct: 753 EPVSSTEASSLGQKDL----EAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPP 808
Query: 1224 RQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQR 1283
R+D T + + + +DG S P + P S D
Sbjct: 809 REDAGT-----QAGAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPSPP----SRRDAGL 859
Query: 1284 PDQPKASSQRLVSTGGRAAD-VCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQ 1342
A+ R V+TG P P+ V + S+ A P E E PV+ VS
Sbjct: 860 QVSLGAAETRSVATGPMTPQAAAPPAFPEVRV-RPGSALAAAVAPPEPAE--PVRDVS-W 915
Query: 1343 DGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASD 1402
D KG + E G A E E G+ +QK E RQ E + G+ +P P P A
Sbjct: 916 DEKGMTWEVYGAAME-VEVLGMAIQKHLE----RQIE-------EHGRQGAPAPPPAA-- 961
Query: 1403 RSRGSSEAAGSVET 1416
R +GSV T
Sbjct: 962 --RAGPGRSGSVRT 973
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 46.2 bits (108), Expect = 3e-04
Identities = 47/220 (21%), Positives = 89/220 (40%), Gaps = 22/220 (10%)
Query: 790 LDDNVMGQEMLSLGTGRESLQEKEKASRKGSF------------GEMGEQTVKAVQKLSQ 837
L+D G + LS G+G QE+E+ + S E+ E+T ++L
Sbjct: 32 LEDGGPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQL 91
Query: 838 QQESVCPRESTVPGHSS-----PCLD--NSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQ 890
QQ P P H P L+ + G Q L Q ++L+PE Q
Sbjct: 92 QQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQ 151
Query: 891 EATPAKTEICPWEVNERTR--EEWTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQ 948
+ ++ P +V E+ R ++ Q + E Q +++ + ++++ ++ + Q
Sbjct: 152 -LMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQ 210
Query: 949 IQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSV 988
+Q+Q+ + E + F Q ++ LLQ G +
Sbjct: 211 LQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQL 250
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 44.7 bits (104), Expect = 8e-04
Identities = 56/289 (19%), Positives = 107/289 (37%), Gaps = 22/289 (7%)
Query: 380 HSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRL 439
HS K+ + GS +S ++ +RS S R K S S + E +PS+
Sbjct: 200 HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKS---RSRSQSRSRSKKEKSRSPSKEKSR 256
Query: 440 GRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKA 499
R + K + +E +QN N + + + + R + ER+
Sbjct: 257 SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQ-------ERRV 309
Query: 500 ERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLG-----SADHRVAEVCPWE 554
E + ++ R S++K+++QS+ + K G +S S D R E
Sbjct: 310 EEEKRGSVS--RGRSQEKSLRQSRS-----RSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 555 VTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMR 614
+ S +R ++ + A S+ +++ D + R +R S+ +
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES 422
Query: 615 KKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEAR 663
+ E + A E+ R + S P P R +S++ +R
Sbjct: 423 SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471
Score = 32.0 bits (71), Expect = 5.2
Identities = 46/248 (18%), Positives = 92/248 (37%), Gaps = 16/248 (6%)
Query: 399 KALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKE 458
++ + SRS R + S + +S ++ + SRS R K+ S+ + S ++
Sbjct: 187 RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEK 246
Query: 459 SLQNQQNAHTSRMLQVCQ-REGSREQEDRGRRMTQGLGERKAERAGK-TGLAMLRQVSRD 516
S + SR + R S++Q + + +G+ K+ + + R S++
Sbjct: 247 SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQE 306
Query: 517 KNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWET 576
+ +++ K V + L+ S + S+++ G K
Sbjct: 307 RRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK-------R 359
Query: 577 SEGAPESRALRQDPGDSQKKRGEARG-------KSEPIDVVPMMRKKPERLVREQEAVCP 629
S SR+ + + +KRG R K + D + P R V ++
Sbjct: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
Query: 630 WESADRGG 637
ES+ R G
Sbjct: 420 SESSQREG 427
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 44.7 bits (104), Expect = 8e-04
Identities = 169/843 (20%), Positives = 305/843 (36%), Gaps = 144/843 (17%)
Query: 449 AALIPSDDKESLQNQQ---NAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKT 505
A+L+P D + SL+ + + H+ R E +++ R+ GER++ R +
Sbjct: 180 ASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRK-----GERRSSRVRQA 234
Query: 506 GLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDS 565
A L + S+ ++ +ETP + L ++L + + E E + E D
Sbjct: 235 RAAKLSEGSQPAEEEEDQETPS--RNLRVRADRNLKTEEEEEEEE-EEEEDDEEEEGDDE 291
Query: 566 GNKA-----------------EICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPID 608
G K+ + P E + P++R+ Q + ++ G E
Sbjct: 292 GQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQ---EVLERGGRFTRSQEEAR 348
Query: 609 VVPMMRKKPERLVREQEAVCPWESADR-----GGLSPGSAPQDPGRIRDKSEAGDSVEAR 663
+ R++ E +E + P E +R GL S P R+ + D +A
Sbjct: 349 KSHLARQQQE---KEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTE-----DRKKAS 400
Query: 664 KVEKPGWEAAGPEAHTPDITK--AEPCPWEASEGGEDGKPAQEAVKDL------PQEKQK 715
V P A+ E P +TK + P P E+ +P + + P
Sbjct: 401 LVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDAD 460
Query: 716 TRKATFWKE--QKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWE 773
TR+ + Q GG L P S + + + P S S +A+ +
Sbjct: 461 TRELLVSQHTVQLVGG----LSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQK 516
Query: 774 AGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQ 833
+ + + A+ P ++++ + + + + SL++KE G T+
Sbjct: 517 DLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKE--------GRRASHTLLPSH 568
Query: 834 KLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEAT 893
+L Q +S R S+ +SSS++ S+ + GSR+ LR + ++
Sbjct: 569 RLKQSADSSSSRSSS--------SSSSSSRSRSRSPDSSGSRS-----HSPLRSKQRDVA 615
Query: 894 PAKTEICPW---EVNERTREE--WTSAQVPRGGESQKDKEKMPGKSEIEDVTAWEKPEGQ 948
A+T P ++ R+ E S R S K PG S + T++ + +
Sbjct: 616 QARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSR-DSSTSYTETKDP 674
Query: 949 IQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLT--- 1005
QE P P P+ Q E + S SV ++ P E+++T
Sbjct: 675 SSGQEVATP----------PVPQLQVCEPKERTSTSSSSVQARRLS-QPESAEKHVTQRL 723
Query: 1006 ---AGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAV--TAPEKPQK 1060
G + C E + +E ++ ++ + +E T+ +P+
Sbjct: 724 QPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRPEN 783
Query: 1061 PTPEWEVAC---------PWGSVG---------PGACSQHPGTLDA-DGPKAGFQELDHM 1101
PE + P GSV P + + + A G AG D
Sbjct: 784 DVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKISVVSATKGVPAG--NSDTE 841
Query: 1102 GCRPGEVCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESA---EQREKALEKGR 1158
G +PG W A A T +K I S + + AG E+ + + +
Sbjct: 842 GGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDE 901
Query: 1159 LTSLGEDVS--KGMAKLC---------QQQETICIWENKDLRESPAQAPKISDLPSSMSS 1207
G+D + KG+ K+C + QE E ++ +E A+ P +P +S
Sbjct: 902 TERNGDDGTHDKGL-KICRTVTQVVPAEGQENGQREEEEEEKEPEAEPP----VPPQVSV 956
Query: 1208 EVA 1210
EVA
Sbjct: 957 EVA 959
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 43.9 bits (102), Expect = 0.001
Identities = 48/192 (25%), Positives = 79/192 (41%), Gaps = 26/192 (13%)
Query: 878 QVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMPGKSEIE 937
++ P+E++ PE +E P + E+ P E EE E ++E++P + E
Sbjct: 10112 EIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEE----------EIPPEEEEVPPEEE-- 10159
Query: 938 DVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQ----DTERPQTLLQMSGSVGSKAA 993
+ E + +E V P V P P P P+ TE+ + + + +K
Sbjct: 10160 ----YVPEEEEFVPEEEVLP--EVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVP 10213
Query: 994 DICPLDVEEN--LTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERA 1051
++ P VEE + + E+ P EV EE + E I + P +V PR
Sbjct: 10214 EV-PKKVEEKRIILPKEEEVLPVEV-TEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPE 10271
Query: 1052 VTAPEKPQKPTP 1063
V P+ PTP
Sbjct: 10272 VIKKAVPEAPTP 10283
Score = 37.4 bits (85), Expect = 0.12
Identities = 95/443 (21%), Positives = 146/443 (32%), Gaps = 85/443 (19%)
Query: 1233 PEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQ 1292
PE + E+ EE+ E+ E+ HE + E P V + R P+
Sbjct: 9905 PEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK- 9963
Query: 1293 RLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEK 1352
P VP K AK P + E++PV ++ E
Sbjct: 9964 -------------PVPVPKK---KEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEV 10007
Query: 1353 GRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAG 1412
+ P E VPV KK E + E P + K + P PAP
Sbjct: 10008 PKKPVPEEKVPVPVPKKVEAPPAKVPEV--PKKPVPEKKV-PVPAP-------------- 10050
Query: 1413 SVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPGGT 1472
+ VEAP AK E+ P + + ++ + +K P
Sbjct: 10051 ------------KKVEAPPAKVPEV-PKKLIPEEKKPTPVPKKVEAPPPKVPKKREP--- 10094
Query: 1473 EEHFSKAAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQWE 1532
A P+E+E + E ++P+ L E +V P+E + L + E
Sbjct: 10095 ---VPVPVALPQEEEVLFEEE------IVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEE 10145
Query: 1533 ITDPEGNKIKGTMADICPGEETGVPSEESGLLALTATRREFFP---TAPEKPLCLLVHGP 1589
PE ++ P EE VP EE EF P PE + V P
Sbjct: 10146 EIPPEEEEV--------PPEEEYVPEEE-----------EFVPEEEVLPEVKPKVPVPAP 10186
Query: 1590 LDHF---FPESKIPCPKVSRPASTFTLEGVRELQGPSGLEPR-TSLAPEPSLQEAESQSS 1645
+ E K+ PK E ++++ + P+ + P +E E +
Sbjct: 10187 VPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPI 10246
Query: 1646 SLTEDSGQVAFEAQYEEFTPPTV 1668
S E + + EE PP V
Sbjct: 10247 SEEEIPEEPPSIEEVEEVAPPRV 10269
Score = 31.6 bits (70), Expect = 6.8
Identities = 47/208 (22%), Positives = 74/208 (35%), Gaps = 43/208 (20%)
Query: 878 QVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMPGKSEIE 937
++ P+E++ PE ++ P E P +VP ++ K+ +P K
Sbjct: 10809 EIAPEEEIAPEEEKPVPVAEEEEP--------------EVPPPAVPEEPKKIIPEKK--- 10851
Query: 938 DVTAWEKPEGQIQKQ---EAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAAD 994
V +KPE K+ E V + P P P P + + + Q+ K
Sbjct: 10852 -VPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVP- 10909
Query: 995 ICPLDVEENLTAGKAEICPWEVGAGAGEERALGAE-------------AIRKSP-NDTGK 1040
E+ K E+ P +V G + R L E +RK P + K
Sbjct: 10910 ------EKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPK 10963
Query: 1041 VSADLGPRERAVTAPE-KPQKPTPEWEV 1067
V + + PE P KP E EV
Sbjct: 10964 VEPKKLEKVKKPAVPEPPPPKPVEEVEV 10991
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 43.5 bits (101), Expect = 0.002
Identities = 98/397 (24%), Positives = 139/397 (35%), Gaps = 57/397 (14%)
Query: 1043 ADLGPRERAVTAPEKPQKPTPEWEVACPWGSV---GPGACSQHPGTLDADGPKAGFQELD 1099
A LGP R+ T P +P + + + G G S P +ADGPKA +
Sbjct: 219 ARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARP 278
Query: 1100 HMGCRPGEVCPWEAQEAAT--SEKAKICPWEVSEGTT-------------GKGLDQKAGS 1144
+ +P P + QE A+ + + P + SE TT + L ++AGS
Sbjct: 279 QIPTKPR--VPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGS 336
Query: 1145 ESAEQREKALEKGRLTSLGEDVSKGMAKLCQ------QQETICIWENKDLRESPAQAPKI 1198
S L GRL L +G K + + + ++ PA P
Sbjct: 337 SS-------LVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPS 389
Query: 1199 SD--LPSSMSSEVAEGHSLEATE---KGDLRQDP-KTGSFPEHITQEKAPAADTEEFTTE 1252
S PS S +V G + E + L P E +E+APAA + +
Sbjct: 390 SSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPA 449
Query: 1253 DGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRL-VSTGGRAADVCPWDVPD 1311
G S +S+ PW P S R P P AS L S + P
Sbjct: 450 LGHPESTP-KSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPA 508
Query: 1312 AGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPE 1371
V S + ++T E+ E V S E AP G PV
Sbjct: 509 LSVESLSSESASQTAGAELLEPPAV--------PKSSSEPAVHAP---GTPGNPVSLSTN 557
Query: 1372 MADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSS 1408
+ E V P Q PQ +P + R+RGSS
Sbjct: 558 SSLASSGELVEPRVEQ-----MPQASPGLAPRTRGSS 589
Score = 32.7 bits (73), Expect = 3.0
Identities = 34/150 (22%), Positives = 52/150 (34%), Gaps = 17/150 (11%)
Query: 840 ESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEI 899
ES P T SS +N +AGS L NG V P+ P+ E TPA +
Sbjct: 310 ESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPV-PKPRGTPKPSEGTPAPRKD 368
Query: 900 CPWEVNERTREE----------------WTSAQVPRGGESQKDKEKMPGKSEIEDVTAWE 943
PW + + S QV GG + + E + +E
Sbjct: 369 PPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFE 428
Query: 944 KPEGQIQKQEAVGPWESVDPGSFSPQPRPQ 973
+ E +++ P + P P+ P+
Sbjct: 429 EEEEDKEEEAPAAPSLATSPALGHPESTPK 458
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 43.1 bits (100), Expect = 0.002
Identities = 71/350 (20%), Positives = 136/350 (38%), Gaps = 42/350 (12%)
Query: 396 LAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAP-SRSPRLGRPKAVSKQAALIPS 454
+A+ A+T + ++ R + + NSG ++ S S R + + QA++ PS
Sbjct: 126 MAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPS 185
Query: 455 DDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTG-------- 506
+++ S + ++ TS +++ + RG LG RK ++A
Sbjct: 186 EEENSESSSESEKTSDQDFTPEKKAAVRAPRRGP-----LGGRKKKKAPSASDSDSKADS 240
Query: 507 -------LAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADH-RVAEVCPWEVTES 558
+AM R S + S ++ V ++ P+ + R + P S
Sbjct: 241 DGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSS 300
Query: 559 ETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPE 618
+ DS I W+ R+D +++++ EAR + E + + +R++ E
Sbjct: 301 SSSDSDSDEVDRISEWK-----------RRD--EARRRELEARRRREQEEELRRLREQ-E 346
Query: 619 RLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSV--EARKVEKPGWEAAGPE 676
+ +E+ E ADRG GS +R+ E + R P + PE
Sbjct: 347 KEEKERRR----ERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPE 402
Query: 677 AHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKEQK 726
A K ++S KP Q+ + P+EKQ+ + + +K
Sbjct: 403 AELEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRK 452
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 43.1 bits (100), Expect = 0.002
Identities = 71/350 (20%), Positives = 136/350 (38%), Gaps = 42/350 (12%)
Query: 396 LAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAP-SRSPRLGRPKAVSKQAALIPS 454
+A+ A+T + ++ R + + NSG ++ S S R + + QA++ PS
Sbjct: 126 MAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPS 185
Query: 455 DDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTG-------- 506
+++ S + ++ TS +++ + RG LG RK ++A
Sbjct: 186 EEENSESSSESEKTSDQDFTPEKKAAVRAPRRGP-----LGGRKKKKAPSASDSDSKADS 240
Query: 507 -------LAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADH-RVAEVCPWEVTES 558
+AM R S + S ++ V ++ P+ + R + P S
Sbjct: 241 DGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSS 300
Query: 559 ETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPE 618
+ DS I W+ R+D +++++ EAR + E + + +R++ E
Sbjct: 301 SSSDSDSDEVDRISEWK-----------RRD--EARRRELEARRRREQEEELRRLREQ-E 346
Query: 619 RLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSV--EARKVEKPGWEAAGPE 676
+ +E+ E ADRG GS +R+ E + R P + PE
Sbjct: 347 KEEKERRR----ERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPE 402
Query: 677 AHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKEQK 726
A K ++S KP Q+ + P+EKQ+ + + +K
Sbjct: 403 AELEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRK 452
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 42.7 bits (99), Expect = 0.003
Identities = 116/546 (21%), Positives = 202/546 (36%), Gaps = 78/546 (14%)
Query: 307 LPAKQENVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDAHHQREAN 366
L QE+ P +G S PE+ W + V + +++++ E + +
Sbjct: 729 LAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLE-EKSEDSIAGS 787
Query: 367 DVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESP--EGQNSG 424
V+ P P ++IK R R E++P + +G
Sbjct: 788 GVEHSTPDTEP------------GKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTG 835
Query: 425 TAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTS----------RMLQV 474
+ P+ P L AV ++ K + Q +Q A T M+
Sbjct: 836 ANEDDSDVPAVVP-LSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAA 894
Query: 475 CQREGSREQ---EDR-----GRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETP 526
+G+R E+R +T+ L + +AE A+L + ++ + +E P
Sbjct: 895 AVADGTRAATIIEERSPSWISASVTEPLEQVEAE------AALLTEEVLEREVIAEEEPP 948
Query: 527 VGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQP---DSGNKAEICPWETSEGAPES 583
+ LP+ ++ G AE+ P VT +ET P + G +A ET+E
Sbjct: 949 TVTEPLPE-NREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAE-ETTEMVSAV 1006
Query: 584 RALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSA 643
L P ++ EA E VP + ++ R +AV E PG+
Sbjct: 1007 SQLTDSPDTTE----EATPVQEVEGGVPDIEEQERRTQEVLQAVA--EKVKEESQLPGT- 1059
Query: 644 PQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEA---SEGGEDGK 700
G D + EA + E+ EA+G + T + K + + ++G G+
Sbjct: 1060 ----GGPEDVLQPVQRAEAERPEEQA-EASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQ 1114
Query: 701 PAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAV---SIQAPGSSE 757
E+ + PQ + + E E+L +S + A+ S++ P SE
Sbjct: 1115 TTPESFEKAPQVTESIESS----ELVTTCQAETLAGVKSQEMVMEQAIPPDSVETPTDSE 1170
Query: 758 CSGSLGSGIAEVCLWEAGDAP-AIQKAEICPWELDDNVMGQEMLSLGTGRESL-QEKEKA 815
GS + +A+ DAP QK EI ++N + S GT E++ +KE+
Sbjct: 1171 TDGS--TPVADF------DAPGTTQKDEIVEIH-EENEVASGTQSGGTEAEAVPAQKERP 1221
Query: 816 SRKGSF 821
SF
Sbjct: 1222 PAPSSF 1227
Score = 40.4 bits (93), Expect = 0.015
Identities = 249/1224 (20%), Positives = 428/1224 (34%), Gaps = 222/1224 (18%)
Query: 394 LGLAIKALTRSRSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRP----KAVSKQA 449
+G RS E S PE G + E+ + P + K + K
Sbjct: 1 MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNG 60
Query: 450 AL-----IPSDDKESLQN-----QQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKA 499
L + D+ SLQ Q+ A + Q E + G+R ++ + +R +
Sbjct: 61 QLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDS 120
Query: 500 ERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELP--KAGLQSLGSADHRVAEVCPWE--- 554
++ T A++ ++ D +ETP +++P ++ L+ L A ++
Sbjct: 121 DKEMATKSAVVHDITDDGQ----EETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVF 176
Query: 555 --------VTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGK-SE 605
V + +T +PD+ ++ + EG E A D D GEA K SE
Sbjct: 177 KFVGFKFTVKKDKTEKPDT---VQLLTVKKDEG--EGAAGAGDHKDPSLGAGEAASKESE 231
Query: 606 PIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKV 665
P +KPE ++ + Q I +E+G +VE K
Sbjct: 232 P----KQSTEKPEETLKRE--------------------QSHAEISPPAESGQAVEECKE 267
Query: 666 EKPGWEAAGPEAHTPDITKAEPCPWE--ASEGGEDGKPAQEAVKDLPQEKQKTRKATFWK 723
E G E + +K+ P SE G K K Q RK T ++
Sbjct: 268 E-------GEEKQEKEPSKSAESPTSPVTSETGSTFK------KFFTQGWAGWRKKTSFR 314
Query: 724 EQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKA 783
+ K ++E+ E + P V + G +E +A L + A + A
Sbjct: 315 KPKED-EVEAS---EKKKEQEPEKVDTEEDGKAE--------VASEKLTASEQAHPQEPA 362
Query: 784 EICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQESVC 843
E + LS + L +E+ S GS G E+ ++ ++ V
Sbjct: 363 ESAH---------EPRLSAEYEKVELPSEEQVS--GSQGPSEEKPAPLATEVFDEKIEVH 411
Query: 844 PRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKT-----E 898
E H S ++ + + ++ GS + + D P QEA PAK E
Sbjct: 412 QEEVVAEVHVST-VEERTEEQKTEVEETAGSVPAEELVEMDAEP--QEAEPAKELVKLKE 468
Query: 899 IC-----PWEVNERTREEWTSAQVPRGGESQ------KDKEKMPGK--SEIEDVTAWEKP 945
C P + + + +E ++ P G S+ +++ K+ G ++ T +K
Sbjct: 469 TCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKL 528
Query: 946 EGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLT 1005
G+ QK + G E + P P E + + S S + +I L+
Sbjct: 529 SGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKG--ESSASSPEEPEEITCLE------ 580
Query: 1006 AGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEW 1065
G AE+ + A E E R+ + P++R E ++ +
Sbjct: 581 KGLAEV---QQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDK 637
Query: 1066 EVACPWGSVGPGACSQHP---GTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKA 1122
+ S A G+++ P+ +++D WEA S K
Sbjct: 638 VKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTS-------VSWEALICVGSSKK 690
Query: 1123 KICPWEVSE---GTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQ---- 1175
+ S+ G G D + E+ + +E + S D +G + Q
Sbjct: 691 RARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSP 750
Query: 1176 -QQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEG--HSLEATEKGDLRQDPKTGSF 1232
+ E + WE+ +P + K S S G HS TE G ++ S
Sbjct: 751 TEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPG---KEESWVSI 807
Query: 1233 PEHIT--QEKAPAADTEEFTTEDGEKT-SHELQSVCPWETTAPADSVSHLDRQR------ 1283
+ I ++K P E+ ED T ++E S P P ++R++
Sbjct: 808 KKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVP--AVVPLSEYDAVEREKMEAQQA 865
Query: 1284 ------PDQPKAS--SQRL-----------VSTGGRAADVCPWDVPD---AGVYKSDSSA 1321
P+Q A+ S+ L V+ G RAA + P A V +
Sbjct: 866 QKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPLEQV 925
Query: 1322 KAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAV 1381
+AE +TE + + V ++ E PE E +G V + E+ EAV
Sbjct: 926 EAEAAL--LTEEVLEREVIAEEEPPTVTEP---LPENREARGDTVVSEAELTP----EAV 976
Query: 1382 CPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVEAPSAKKAEICPWE 1441
E+ G + +EA+ + ET + ++ ++P + E
Sbjct: 977 TAAETAGPLG------------AEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQE 1024
Query: 1442 AGGGAAEEGEQERESQGQGEMFLQKA-------GPGGTEEHFSKAAAKPREQEAVCPGEG 1494
GG + EQER +Q + +K G GG E+ + EA P E
Sbjct: 1025 VEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPV----QRAEAERPEEQ 1080
Query: 1495 TGSGGLLPQSGALDPELKVSPKEA 1518
+ GL ++ D LKV +EA
Sbjct: 1081 AEASGLKKET---DVVLKVDAQEA 1101
Score = 36.6 bits (83), Expect = 0.21
Identities = 164/819 (20%), Positives = 306/819 (37%), Gaps = 124/819 (15%)
Query: 348 RAGENEMDAEDAHHQREANDVDEDRPKIF---PKSHS-LKAPVQQGSMRSLGLAIKAL-- 401
R + EM + A +D E+ P+I P S S L+ Q ++ + K +
Sbjct: 118 RDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFK 177
Query: 402 ------TRSRSTYREKESVE----ESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAAL 451
T + + ++V+ + EG+ + AG+ + P LG +A SK++
Sbjct: 178 FVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDH-----KDPSLGAGEAASKESEP 232
Query: 452 IPSDDK--ESLQNQQN-------AHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERA 502
S +K E+L+ +Q+ A + + ++ C+ EG +QE + +
Sbjct: 233 KQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSET 292
Query: 503 GKTGLAMLRQ----VSRDKNIKQSKETPVGWQELPK-AGLQSLGSADHRVAEVCPWEVTE 557
G T Q + + ++ KE V E K + + + + AEV ++T
Sbjct: 293 GSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTA 352
Query: 558 SETRQP----DSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGK--SEPIDV-- 609
SE P +S ++ + P + G S++K + E I+V
Sbjct: 353 SEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQ 412
Query: 610 VPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSE-AGDSVEARKVEKP 668
++ + V E+ E + G P + ++E A + V+ ++
Sbjct: 413 EEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVS 472
Query: 669 GWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKE---- 724
G + +PD K P E + +QE +K +K +T K+
Sbjct: 473 GEDPTQGADLSPD-EKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGK 531
Query: 725 ----QKPGGDLES----LCPWESTDF----RGPSAVSIQAPGSSECSGSLGSGIAEVCLW 772
++ GGD ES P +S D +G S+ S +P E L G+AEV
Sbjct: 532 KQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESSAS--SPEEPEEITCLEKGLAEVQQD 589
Query: 773 EAGDAPAIQKAE-----ICPW-ELDDNVMGQEMLSLGTGRESLQEKEK------ASRKGS 820
+ A E + PW V ++ + + + E +K +S + +
Sbjct: 590 GEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTEST 649
Query: 821 FGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKA--GSQFLCNGGSRA-- 876
EM E+ +V++ + +E +++V + C+ +S +A GS GG +A
Sbjct: 650 ASEMQEEMKGSVEE-PKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMG 708
Query: 877 -----------TQVCPQEDLRPEAQEATPAKTEICPWEVNERTREE----WTSAQ---VP 918
+ + + +QE P + P + T E W S + P
Sbjct: 709 GDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTP 768
Query: 919 RGGESQKDKEKMPGKSE-------IEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPR 971
R +K K K+ KSE +E T P+ + K+E+ + PG +P
Sbjct: 769 R----KKSKSKLEEKSEDSIAGSGVEHST----PDTEPGKEESWVSIKKFIPGRRKKRP- 819
Query: 972 PQDTERPQTLLQMSGSVGSKAAD-----ICPLDVEENLTAGKAEICPWEVGAGAGEERAL 1026
D ++ Q ++ +G G+ D + PL + + K E + A E++A
Sbjct: 820 --DGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAA 877
Query: 1027 GAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEW 1065
+ S + ++A + RA T E + +P W
Sbjct: 878 TEVSKELSESQVHMMAAAVADGTRAATIIE---ERSPSW 913
Score = 34.3 bits (77), Expect = 1.0
Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 6/153 (3%)
Query: 556 TESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRK 615
TE E +P + + E P +++ ES A+ Q D K EA K+ ++V
Sbjct: 1594 TEKEGEEPQASAQDET-PITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVN 1652
Query: 616 KPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGP 675
+ +E V P E + GG S P+D G S+ K ++ G + P
Sbjct: 1653 DQQL----EEVVLPSEE-EGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDP 1707
Query: 676 EAHTPDITKAEPCPWEASEGGEDGKPAQEAVKD 708
E + + E + P Q+ +D
Sbjct: 1708 ENQNSALADTDASGGLTKESPDTNGPKQKEKED 1740
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 42.7 bits (99), Expect = 0.003
Identities = 116/546 (21%), Positives = 202/546 (36%), Gaps = 78/546 (14%)
Query: 307 LPAKQENVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDAHHQREAN 366
L QE+ P +G S PE+ W + V + +++++ E + +
Sbjct: 631 LAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLE-EKSEDSIAGS 689
Query: 367 DVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESP--EGQNSG 424
V+ P P ++IK R R E++P + +G
Sbjct: 690 GVEHSTPDTEP------------GKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTG 737
Query: 425 TAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTS----------RMLQV 474
+ P+ P L AV ++ K + Q +Q A T M+
Sbjct: 738 ANEDDSDVPAVVP-LSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAA 796
Query: 475 CQREGSREQ---EDR-----GRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETP 526
+G+R E+R +T+ L + +AE A+L + ++ + +E P
Sbjct: 797 AVADGTRAATIIEERSPSWISASVTEPLEQVEAE------AALLTEEVLEREVIAEEEPP 850
Query: 527 VGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQP---DSGNKAEICPWETSEGAPES 583
+ LP+ ++ G AE+ P VT +ET P + G +A ET+E
Sbjct: 851 TVTEPLPE-NREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAE-ETTEMVSAV 908
Query: 584 RALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSA 643
L P ++ EA E VP + ++ R +AV E PG+
Sbjct: 909 SQLTDSPDTTE----EATPVQEVEGGVPDIEEQERRTQEVLQAVA--EKVKEESQLPGT- 961
Query: 644 PQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEA---SEGGEDGK 700
G D + EA + E+ EA+G + T + K + + ++G G+
Sbjct: 962 ----GGPEDVLQPVQRAEAERPEEQA-EASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQ 1016
Query: 701 PAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAV---SIQAPGSSE 757
E+ + PQ + + E E+L +S + A+ S++ P SE
Sbjct: 1017 TTPESFEKAPQVTESIESS----ELVTTCQAETLAGVKSQEMVMEQAIPPDSVETPTDSE 1072
Query: 758 CSGSLGSGIAEVCLWEAGDAP-AIQKAEICPWELDDNVMGQEMLSLGTGRESL-QEKEKA 815
GS + +A+ DAP QK EI ++N + S GT E++ +KE+
Sbjct: 1073 TDGS--TPVADF------DAPGTTQKDEIVEIH-EENEVASGTQSGGTEAEAVPAQKERP 1123
Query: 816 SRKGSF 821
SF
Sbjct: 1124 PAPSSF 1129
Score = 36.6 bits (83), Expect = 0.21
Identities = 228/1117 (20%), Positives = 396/1117 (35%), Gaps = 208/1117 (18%)
Query: 487 GRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELP--KAGLQSLGSAD 544
G+R ++ + +R +++ T A++ ++ D +ETP +++P ++ L+ L
Sbjct: 10 GQRDSEDVSKRDSDKEMATKSAVVHDITDDGQ----EETPEIIEQIPSSESNLEELTQPT 65
Query: 545 HRVAEVCPWE-----------VTESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDS 593
A ++ V + +T +PD+ ++ + EG E A D D
Sbjct: 66 ESQANDIGFKKVFKFVGFKFTVKKDKTEKPDT---VQLLTVKKDEG--EGAAGAGDHKDP 120
Query: 594 QKKRGEARGK-SEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRD 652
GEA K SEP +KPE ++ + Q I
Sbjct: 121 SLGAGEAASKESEP----KQSTEKPEETLKRE--------------------QSHAEISP 156
Query: 653 KSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWE--ASEGGEDGKPAQEAVKDLP 710
+E+G +VE K E G E + +K+ P SE G K K
Sbjct: 157 PAESGQAVEECKEE-------GEEKQEKEPSKSAESPTSPVTSETGSTFK------KFFT 203
Query: 711 QEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVC 770
Q RK T +++ K ++E+ E + P V + G +E +A
Sbjct: 204 QGWAGWRKKTSFRKPKED-EVEAS---EKKKEQEPEKVDTEEDGKAE--------VASEK 251
Query: 771 LWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVK 830
L + A + AE + LS + L +E+ S GS G E+
Sbjct: 252 LTASEQAHPQEPAESAH---------EPRLSAEYEKVELPSEEQVS--GSQGPSEEKPAP 300
Query: 831 AVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQ 890
++ ++ V E H S ++ + + ++ GS + + D P Q
Sbjct: 301 LATEVFDEKIEVHQEEVVAEVHVST-VEERTEEQKTEVEETAGSVPAEELVEMDAEP--Q 357
Query: 891 EATPAKT-----EIC-----PWEVNERTREEWTSAQVPRGGESQ------KDKEKMPGK- 933
EA PAK E C P + + + +E ++ P G S+ +++ K+ G
Sbjct: 358 EAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSP 417
Query: 934 -SEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKA 992
++ T +K G+ QK + G E + P P E + + S S +
Sbjct: 418 LKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKG--ESSASSPEEP 475
Query: 993 ADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAV 1052
+I L+ G AE+ + A E E R+ + P++R
Sbjct: 476 EEITCLE------KGLAEV---QQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVR 526
Query: 1053 TAPEKPQKPTPEWEVACPWGSVGPGACSQHP---GTLDADGPKAGFQELDHMGCRPGEVC 1109
E ++ + + S A G+++ P+ +++D
Sbjct: 527 RPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTS-------V 579
Query: 1110 PWEAQEAATSEKAKICPWEVSE---GTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDV 1166
WEA S K + S+ G G D + E+ + +E + S D
Sbjct: 580 SWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDP 639
Query: 1167 SKGMAKLCQ-----QQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEG--HSLEATE 1219
+G + Q + E + WE+ +P + K S S G HS TE
Sbjct: 640 GQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTE 699
Query: 1220 KGDLRQDPKTGSFPEHIT--QEKAPAADTEEFTTEDGEKT-SHELQSVCPWETTAPADSV 1276
G ++ S + I ++K P E+ ED T ++E S P P
Sbjct: 700 PG---KEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVP--AVVPLSEY 754
Query: 1277 SHLDRQR------------PDQPKAS--SQRL-----------VSTGGRAADVCPWDVPD 1311
++R++ P+Q A+ S+ L V+ G RAA + P
Sbjct: 755 DAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPS 814
Query: 1312 ---AGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQK 1368
A V + +AE +TE + + V ++ E PE E +G V
Sbjct: 815 WISASVTEPLEQVEAEAAL--LTEEVLEREVIAEEEPPTVTEP---LPENREARGDTVVS 869
Query: 1369 KPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVVE 1428
+ E+ EAV E+ G + +EA+ + ET + ++ +
Sbjct: 870 EAELTP----EAVTAAETAGPLG------------AEEGTEASAAEETTEMVSAVSQLTD 913
Query: 1429 APSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKA-------GPGGTEEHFSKAAA 1481
+P + E GG + EQER +Q + +K G GG E+
Sbjct: 914 SPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPV-- 971
Query: 1482 KPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEA 1518
+ EA P E + GL ++ D LKV +EA
Sbjct: 972 --QRAEAERPEEQAEASGLKKET---DVVLKVDAQEA 1003
Score = 36.6 bits (83), Expect = 0.21
Identities = 164/819 (20%), Positives = 306/819 (37%), Gaps = 124/819 (15%)
Query: 348 RAGENEMDAEDAHHQREANDVDEDRPKIF---PKSHS-LKAPVQQGSMRSLGLAIKAL-- 401
R + EM + A +D E+ P+I P S S L+ Q ++ + K +
Sbjct: 20 RDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFK 79
Query: 402 ------TRSRSTYREKESVE----ESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAAL 451
T + + ++V+ + EG+ + AG+ + P LG +A SK++
Sbjct: 80 FVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDH-----KDPSLGAGEAASKESEP 134
Query: 452 IPSDDK--ESLQNQQN-------AHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERA 502
S +K E+L+ +Q+ A + + ++ C+ EG +QE + +
Sbjct: 135 KQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSET 194
Query: 503 GKTGLAMLRQ----VSRDKNIKQSKETPVGWQELPK-AGLQSLGSADHRVAEVCPWEVTE 557
G T Q + + ++ KE V E K + + + + AEV ++T
Sbjct: 195 GSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTA 254
Query: 558 SETRQP----DSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGK--SEPIDV-- 609
SE P +S ++ + P + G S++K + E I+V
Sbjct: 255 SEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQ 314
Query: 610 VPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSE-AGDSVEARKVEKP 668
++ + V E+ E + G P + ++E A + V+ ++
Sbjct: 315 EEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVS 374
Query: 669 GWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKTRKATFWKE---- 724
G + +PD K P E + +QE +K +K +T K+
Sbjct: 375 GEDPTQGADLSPD-EKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGK 433
Query: 725 ----QKPGGDLES----LCPWESTDF----RGPSAVSIQAPGSSECSGSLGSGIAEVCLW 772
++ GGD ES P +S D +G S+ S +P E L G+AEV
Sbjct: 434 KQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESSAS--SPEEPEEITCLEKGLAEVQQD 491
Query: 773 EAGDAPAIQKAE-----ICPW-ELDDNVMGQEMLSLGTGRESLQEKEK------ASRKGS 820
+ A E + PW V ++ + + + E +K +S + +
Sbjct: 492 GEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTEST 551
Query: 821 FGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKA--GSQFLCNGGSRA-- 876
EM E+ +V++ + +E +++V + C+ +S +A GS GG +A
Sbjct: 552 ASEMQEEMKGSVEE-PKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMG 610
Query: 877 -----------TQVCPQEDLRPEAQEATPAKTEICPWEVNERTREE----WTSAQ---VP 918
+ + + +QE P + P + T E W S + P
Sbjct: 611 GDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTP 670
Query: 919 RGGESQKDKEKMPGKSE-------IEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPR 971
R +K K K+ KSE +E T P+ + K+E+ + PG +P
Sbjct: 671 R----KKSKSKLEEKSEDSIAGSGVEHST----PDTEPGKEESWVSIKKFIPGRRKKRP- 721
Query: 972 PQDTERPQTLLQMSGSVGSKAAD-----ICPLDVEENLTAGKAEICPWEVGAGAGEERAL 1026
D ++ Q ++ +G G+ D + PL + + K E + A E++A
Sbjct: 722 --DGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAA 779
Query: 1027 GAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEW 1065
+ S + ++A + RA T E + +P W
Sbjct: 780 TEVSKELSESQVHMMAAAVADGTRAATIIE---ERSPSW 815
Score = 34.3 bits (77), Expect = 1.0
Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 6/153 (3%)
Query: 556 TESETRQPDSGNKAEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRK 615
TE E +P + + E P +++ ES A+ Q D K EA K+ ++V
Sbjct: 1496 TEKEGEEPQASAQDET-PITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVN 1554
Query: 616 KPERLVREQEAVCPWESADRGGLSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGP 675
+ +E V P E + GG S P+D G S+ K ++ G + P
Sbjct: 1555 DQQL----EEVVLPSEE-EGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDP 1609
Query: 676 EAHTPDITKAEPCPWEASEGGEDGKPAQEAVKD 708
E + + E + P Q+ +D
Sbjct: 1610 ENQNSALADTDASGGLTKESPDTNGPKQKEKED 1642
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 42.7 bits (99), Expect = 0.003
Identities = 76/342 (22%), Positives = 128/342 (37%), Gaps = 58/342 (16%)
Query: 412 ESVEESPEGQNSGTAGESMGAPSRSPRL--------GRPKAVSKQAALIPSDDKESLQNQ 463
E+ E S G+ E + P+++ R +A Q +L PSD + S +
Sbjct: 94 EAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVS-EEV 152
Query: 464 QNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSK 523
+ H+ + + + E E +G R E+ E G+T A L + + IK K
Sbjct: 153 KTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIK--K 210
Query: 524 ETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAPES 583
E V E AG + + E T S+ P + S+G P S
Sbjct: 211 EELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHP-----------QESKGQPRS 259
Query: 584 RALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSA 643
+ + + GE SE V R +P R + + +GG P
Sbjct: 260 Q--------EESEEGEEDATSE----VDKRRTRP----RHHHGRSRPDRSSQGGSLPS-- 301
Query: 644 PQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGED--GKP 701
++ G +++SE + A EK + H+ +E E E GE+ G P
Sbjct: 302 -EEKGHPQEESEESNVSMASLGEK-------RDHHSTHYRASE----EEPEYGEEIKGYP 349
Query: 702 AQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFR 743
+A +DL E+ + R + ++ +P +S W+ D R
Sbjct: 350 GVQAPEDLEWERYRGRGSEEYRAPRP----QSEESWDEEDKR 387
Score = 38.1 bits (87), Expect = 0.072
Identities = 77/321 (23%), Positives = 117/321 (36%), Gaps = 41/321 (12%)
Query: 977 RPQTLLQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPN 1036
+P LL + G+VG A + P+D N G C EV + A + + +P
Sbjct: 2 QPTLLLSLLGAVGLAAVNSMPVD-NRNHNEGMVTRCIIEVLSNALSKSS--------APP 52
Query: 1037 DTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQ 1096
T + L + V E + ++EV + +A P
Sbjct: 53 ITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAP----G 108
Query: 1097 ELDHMGCRPGEVCPWEAQEAATSEKAKICPW-------EVSEGTTGKGLDQKAGSESAEQ 1149
E D G + W + E+A W +VSE + ++ + E+
Sbjct: 109 EEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEE 168
Query: 1150 REKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRE-SPAQAPKISDLPSSMSSE 1208
+ +KG GED S+ L + ET +N L E A A K +L + +
Sbjct: 169 EGENYQKG---ERGEDSSE-EKHLEEPGET----QNAFLNERKQASAIKKEELVARSETH 220
Query: 1209 VAEGHSLEAT---EKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVC 1265
A GHS E T EK +TGS H + K EE +E+GE+ + S
Sbjct: 221 AA-GHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEE--SEEGEE---DATSEV 274
Query: 1266 PWETTAPADSVSHLDRQRPDQ 1286
T P H R RPD+
Sbjct: 275 DKRRTRPR---HHHGRSRPDR 292
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 42.7 bits (99), Expect = 0.003
Identities = 77/309 (24%), Positives = 117/309 (37%), Gaps = 39/309 (12%)
Query: 1191 SPAQAP----KISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADT 1246
SP+ AP K +LP S +V E EAT D+ + PK PE I + K P+ +
Sbjct: 209 SPSPAPEKKEKTPELPEP-SVKVKEPSVQEATSTSDILKVPK----PEPIPEPKEPSPEK 263
Query: 1247 EEFTTEDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCP 1306
++ EKT +S + + S SH RP + S R S R + P
Sbjct: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSH---TRPRRRHRSRSRSYSPRRRPS---P 317
Query: 1307 WDVPDAGVYKSDSSAKAETCPWEVTERIPVK-----GVSRQDGKGDSQEEKGRAPEKSEP 1361
P + + P R PV+ S S + R+P K P
Sbjct: 318 RRRPSP--RRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP 375
Query: 1362 K--GVPVQK----KPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGS--SEAAGS 1413
K P +K P + R++ P + K P P S+R+R S S + G
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK-TRHSPTPQQSNRTRKSRVSVSPGR 434
Query: 1414 VETRVAEVCLWEVVEAPS----AKKAEICPWEAGGG----AAEEGEQERESQGQGEMFLQ 1465
+V + E E+PS +K E+ E G AA+ +Q R+ + Q +
Sbjct: 435 TSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSS 494
Query: 1466 KAGPGGTEE 1474
+G + E
Sbjct: 495 DSGSSSSSE 503
Score = 33.5 bits (75), Expect = 1.8
Identities = 79/401 (19%), Positives = 142/401 (35%), Gaps = 40/401 (9%)
Query: 345 EKSRAGENEMDAEDAHHQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRS 404
++ + ++ + E + +RE + R P +PV++ RS + + T+S
Sbjct: 148 DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKS 207
Query: 405 RS---TYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQ 461
RS +KE E PE A S S L PK PS +K S +
Sbjct: 208 RSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKK 267
Query: 462 NQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQ 521
++ T + R S+ + R R+ R+ + R+ S +
Sbjct: 268 EKEKEKT----RPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSP 323
Query: 522 SKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSEGAP 581
+ TP P +S R + S + S + + P TS +P
Sbjct: 324 RRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTS--SP 381
Query: 582 ESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKP-----ERLVREQEAVCPWESADR- 635
+ R P S +R S P P R P R + + +V P ++ +
Sbjct: 382 PRKTRRLSPSASPPRR--RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKV 439
Query: 636 -------GGLSPGSAPQDPGRIR---------DKSEAGDSVEARKVEKPGWEAAGPEAHT 679
SP AP+ P ++ K A DSV+ R+ + + + ++ +
Sbjct: 440 TKHKGTEKRESPSPAPK-PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGS 498
Query: 680 PDITKAEPCPWEASEGGEDGK-----PAQEAVKDLPQEKQK 715
++ E + GE G+ P++ A P+++QK
Sbjct: 499 SSSSEDERPKRSHVKNGEVGRRRRHSPSRSA-SPSPRKRQK 538
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 42.4 bits (98), Expect = 0.004
Identities = 127/605 (20%), Positives = 183/605 (30%), Gaps = 69/605 (11%)
Query: 890 QEATPAKTEICPWEVNERTREEWTSAQV-PRGGESQKDKEKMPGKSEIEDVTAWEKPEGQ 948
+E P T+ P E SA P+ KE P + T +KP
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445
Query: 949 IQKQEA-VGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAG 1007
K+ A P E + P P P T + + + K P +
Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505
Query: 1008 KAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTP---- 1063
A P E+ EE + T K +A P+E A T P++P TP
Sbjct: 506 PAPTTPEELAPTTPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 1064 -----EWEVACPWGSVGPGACSQHPGTLDADGPK----AGFQELDHMGC-RPGEVCPWEA 1113
E P G+ P T PK +E C +P P
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623
Query: 1114 QEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKL 1173
E A P E + TT KG E A K K L +KG
Sbjct: 624 APTTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPK---KPAPKELAPTTTKGPTST 679
Query: 1174 CQQ-------QETICIWENKDLRESPAQ-APKISDLPSSMSSEVAEGH------------ 1213
+ET + +P + AP + P +SEV+
Sbjct: 680 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 739
Query: 1214 -------SLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCP 1266
S E T K L PK P K PAA E TT +KT+ P
Sbjct: 740 DESTPELSAEPTPKA-LENSPKEPGVP----TTKTPAATKPEMTTTAKDKTTERDLRTTP 794
Query: 1267 WETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETC 1326
ETT A ++ K + ++ +T V D +K +
Sbjct: 795 -ETTTAAPKMT--KETATTTEKTTESKITAT---TTQVTSTTTQDTTPFKITTLKTTTLA 848
Query: 1327 PWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWES 1386
P T + + + ++ + K RA P +KP A + P
Sbjct: 849 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT--TPKPQKPTKAPKKPTSTKKPKTM 906
Query: 1387 QDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVV---EAPSAKKAEICPWEAG 1443
+ P P R S+ + +R+AE L + P++K E+ P
Sbjct: 907 PRVRKPKTTPTP----RKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSED 962
Query: 1444 GGAAE 1448
G AE
Sbjct: 963 AGGAE 967
Score = 35.0 bits (79), Expect = 0.61
Identities = 58/263 (22%), Positives = 92/263 (34%), Gaps = 31/263 (11%)
Query: 806 RESLQEKEKASRKGSFGEMGEQTVKAVQKLS-QQQESVCPRESTVPGHSSPCLDNSSSKA 864
R SL S++ S E TV+ + + +Q S +E T + ++ +S+K
Sbjct: 127 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 186
Query: 865 GSQFLCNGGSRATQVCPQEDLRPEAQEATPAK--TEICPWEVNERTREEWTSAQVPRGGE 922
L + P+ + + T K T P E T +E T +
Sbjct: 187 ----LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 242
Query: 923 SQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSP-QPRPQDTERPQTL 981
+ K+ KS T ++P P + +P +P +P P T+ P
Sbjct: 243 TPKEPAPTTTKSA---PTTPKEP----------APTTTKEPAPTTPKEPAPTTTKEP--- 286
Query: 982 LQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKV 1041
+K+A P + A P E +E K P T K
Sbjct: 287 ----APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT---PTTPKEPAPTTKE 339
Query: 1042 SADLGPRERAVTAPEKPQKPTPE 1064
A P+E A TAP+KP TP+
Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPK 362
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 42.4 bits (98), Expect = 0.004
Identities = 127/605 (20%), Positives = 183/605 (30%), Gaps = 69/605 (11%)
Query: 890 QEATPAKTEICPWEVNERTREEWTSAQV-PRGGESQKDKEKMPGKSEIEDVTAWEKPEGQ 948
+E P T+ P E SA P+ KE P + T +KP
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486
Query: 949 IQKQEA-VGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAG 1007
K+ A P E + P P P T + + + K P +
Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546
Query: 1008 KAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTP---- 1063
A P E+ EE + T K +A P+E A T P++P TP
Sbjct: 547 PAPTTPEELAPTTPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604
Query: 1064 -----EWEVACPWGSVGPGACSQHPGTLDADGPK----AGFQELDHMGC-RPGEVCPWEA 1113
E P G+ P T PK +E C +P P
Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664
Query: 1114 QEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKL 1173
E A P E + TT KG E A K K L +KG
Sbjct: 665 APTTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPK---KPAPKELAPTTTKGPTST 720
Query: 1174 CQQ-------QETICIWENKDLRESPAQ-APKISDLPSSMSSEVAEGH------------ 1213
+ET + +P + AP + P +SEV+
Sbjct: 721 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 780
Query: 1214 -------SLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCP 1266
S E T K L PK P K PAA E TT +KT+ P
Sbjct: 781 DESTPELSAEPTPKA-LENSPKEPGVP----TTKTPAATKPEMTTTAKDKTTERDLRTTP 835
Query: 1267 WETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETC 1326
ETT A ++ K + ++ +T V D +K +
Sbjct: 836 -ETTTAAPKMT--KETATTTEKTTESKITAT---TTQVTSTTTQDTTPFKITTLKTTTLA 889
Query: 1327 PWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWES 1386
P T + + + ++ + K RA P +KP A + P
Sbjct: 890 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT--TPKPQKPTKAPKKPTSTKKPKTM 947
Query: 1387 QDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVV---EAPSAKKAEICPWEAG 1443
+ P P R S+ + +R+AE L + P++K E+ P
Sbjct: 948 PRVRKPKTTPTP----RKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSED 1003
Query: 1444 GGAAE 1448
G AE
Sbjct: 1004 AGGAE 1008
Score = 35.0 bits (79), Expect = 0.61
Identities = 58/263 (22%), Positives = 92/263 (34%), Gaps = 31/263 (11%)
Query: 806 RESLQEKEKASRKGSFGEMGEQTVKAVQKLS-QQQESVCPRESTVPGHSSPCLDNSSSKA 864
R SL S++ S E TV+ + + +Q S +E T + ++ +S+K
Sbjct: 168 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 227
Query: 865 GSQFLCNGGSRATQVCPQEDLRPEAQEATPAK--TEICPWEVNERTREEWTSAQVPRGGE 922
L + P+ + + T K T P E T +E T +
Sbjct: 228 ----LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 283
Query: 923 SQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSP-QPRPQDTERPQTL 981
+ K+ KS T ++P P + +P +P +P P T+ P
Sbjct: 284 TPKEPAPTTTKSA---PTTPKEP----------APTTTKEPAPTTPKEPAPTTTKEP--- 327
Query: 982 LQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKV 1041
+K+A P + A P E +E K P T K
Sbjct: 328 ----APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT---PTTPKEPAPTTKE 380
Query: 1042 SADLGPRERAVTAPEKPQKPTPE 1064
A P+E A TAP+KP TP+
Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPK 403
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 42.4 bits (98), Expect = 0.004
Identities = 127/605 (20%), Positives = 183/605 (30%), Gaps = 69/605 (11%)
Query: 890 QEATPAKTEICPWEVNERTREEWTSAQV-PRGGESQKDKEKMPGKSEIEDVTAWEKPEGQ 948
+E P T+ P E SA P+ KE P + T +KP
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538
Query: 949 IQKQEA-VGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAG 1007
K+ A P E + P P P T + + + K P +
Sbjct: 539 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598
Query: 1008 KAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTP---- 1063
A P E+ EE + T K +A P+E A T P++P TP
Sbjct: 599 PAPTTPEELAPTTPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656
Query: 1064 -----EWEVACPWGSVGPGACSQHPGTLDADGPK----AGFQELDHMGC-RPGEVCPWEA 1113
E P G+ P T PK +E C +P P
Sbjct: 657 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716
Query: 1114 QEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKL 1173
E A P E + TT KG E A K K L +KG
Sbjct: 717 APTTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPK---KPAPKELAPTTTKGPTST 772
Query: 1174 CQQ-------QETICIWENKDLRESPAQ-APKISDLPSSMSSEVAEGH------------ 1213
+ET + +P + AP + P +SEV+
Sbjct: 773 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832
Query: 1214 -------SLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCP 1266
S E T K L PK P K PAA E TT +KT+ P
Sbjct: 833 DESTPELSAEPTPKA-LENSPKEPGVP----TTKTPAATKPEMTTTAKDKTTERDLRTTP 887
Query: 1267 WETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETC 1326
ETT A ++ K + ++ +T V D +K +
Sbjct: 888 -ETTTAAPKMT--KETATTTEKTTESKITAT---TTQVTSTTTQDTTPFKITTLKTTTLA 941
Query: 1327 PWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWES 1386
P T + + + ++ + K RA P +KP A + P
Sbjct: 942 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT--TPKPQKPTKAPKKPTSTKKPKTM 999
Query: 1387 QDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVV---EAPSAKKAEICPWEAG 1443
+ P P R S+ + +R+AE L + P++K E+ P
Sbjct: 1000 PRVRKPKTTPTP----RKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSED 1055
Query: 1444 GGAAE 1448
G AE
Sbjct: 1056 AGGAE 1060
Score = 35.0 bits (79), Expect = 0.61
Identities = 58/263 (22%), Positives = 92/263 (34%), Gaps = 31/263 (11%)
Query: 806 RESLQEKEKASRKGSFGEMGEQTVKAVQKLS-QQQESVCPRESTVPGHSSPCLDNSSSKA 864
R SL S++ S E TV+ + + +Q S +E T + ++ +S+K
Sbjct: 220 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 279
Query: 865 GSQFLCNGGSRATQVCPQEDLRPEAQEATPAK--TEICPWEVNERTREEWTSAQVPRGGE 922
L + P+ + + T K T P E T +E T +
Sbjct: 280 ----LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 335
Query: 923 SQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSP-QPRPQDTERPQTL 981
+ K+ KS T ++P P + +P +P +P P T+ P
Sbjct: 336 TPKEPAPTTTKSA---PTTPKEP----------APTTTKEPAPTTPKEPAPTTTKEP--- 379
Query: 982 LQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKV 1041
+K+A P + A P E +E K P T K
Sbjct: 380 ----APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT---PTTPKEPAPTTKE 432
Query: 1042 SADLGPRERAVTAPEKPQKPTPE 1064
A P+E A TAP+KP TP+
Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPK 455
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 42.4 bits (98), Expect = 0.004
Identities = 127/605 (20%), Positives = 183/605 (30%), Gaps = 69/605 (11%)
Query: 890 QEATPAKTEICPWEVNERTREEWTSAQV-PRGGESQKDKEKMPGKSEIEDVTAWEKPEGQ 948
+E P T+ P E SA P+ KE P + T +KP
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579
Query: 949 IQKQEA-VGPWESVDPGSFSPQPRPQDTERPQTLLQMSGSVGSKAADICPLDVEENLTAG 1007
K+ A P E + P P P T + + + K P +
Sbjct: 580 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639
Query: 1008 KAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTP---- 1063
A P E+ EE + T K +A P+E A T P++P TP
Sbjct: 640 PAPTTPEELAPTTPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697
Query: 1064 -----EWEVACPWGSVGPGACSQHPGTLDADGPK----AGFQELDHMGC-RPGEVCPWEA 1113
E P G+ P T PK +E C +P P
Sbjct: 698 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 757
Query: 1114 QEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKL 1173
E A P E + TT KG E A K K L +KG
Sbjct: 758 APTTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPK---KPAPKELAPTTTKGPTST 813
Query: 1174 CQQ-------QETICIWENKDLRESPAQ-APKISDLPSSMSSEVAEGH------------ 1213
+ET + +P + AP + P +SEV+
Sbjct: 814 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873
Query: 1214 -------SLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCP 1266
S E T K L PK P K PAA E TT +KT+ P
Sbjct: 874 DESTPELSAEPTPKA-LENSPKEPGVP----TTKTPAATKPEMTTTAKDKTTERDLRTTP 928
Query: 1267 WETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETC 1326
ETT A ++ K + ++ +T V D +K +
Sbjct: 929 -ETTTAAPKMT--KETATTTEKTTESKITAT---TTQVTSTTTQDTTPFKITTLKTTTLA 982
Query: 1327 PWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWES 1386
P T + + + ++ + K RA P +KP A + P
Sbjct: 983 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT--TPKPQKPTKAPKKPTSTKKPKTM 1040
Query: 1387 QDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEVCLWEVV---EAPSAKKAEICPWEAG 1443
+ P P R S+ + +R+AE L + P++K E+ P
Sbjct: 1041 PRVRKPKTTPTP----RKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSED 1096
Query: 1444 GGAAE 1448
G AE
Sbjct: 1097 AGGAE 1101
Score = 35.0 bits (79), Expect = 0.61
Identities = 58/263 (22%), Positives = 92/263 (34%), Gaps = 31/263 (11%)
Query: 806 RESLQEKEKASRKGSFGEMGEQTVKAVQKLS-QQQESVCPRESTVPGHSSPCLDNSSSKA 864
R SL S++ S E TV+ + + +Q S +E T + ++ +S+K
Sbjct: 261 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 320
Query: 865 GSQFLCNGGSRATQVCPQEDLRPEAQEATPAK--TEICPWEVNERTREEWTSAQVPRGGE 922
L + P+ + + T K T P E T +E T +
Sbjct: 321 ----LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 376
Query: 923 SQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSP-QPRPQDTERPQTL 981
+ K+ KS T ++P P + +P +P +P P T+ P
Sbjct: 377 TPKEPAPTTTKSA---PTTPKEP----------APTTTKEPAPTTPKEPAPTTTKEP--- 420
Query: 982 LQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKV 1041
+K+A P + A P E +E K P T K
Sbjct: 421 ----APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT---PTTPKEPAPTTKE 473
Query: 1042 SADLGPRERAVTAPEKPQKPTPE 1064
A P+E A TAP+KP TP+
Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPK 496
>gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]
Length = 1523
Score = 42.4 bits (98), Expect = 0.004
Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 19/135 (14%)
Query: 959 ESVDPGSF----SPQPRPQDTER--PQTLLQMSGSVGSKAADICPLDVEENLTAGKAEIC 1012
+S++P S S PQ+ R P L Q S + + L+ E +T ++ C
Sbjct: 900 DSLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYC 959
Query: 1013 PWEVGAGAGEERALGAEAIRKS---------PNDTGKVSADLGPRERAVTAPEKPQKPTP 1063
EV AG G+++ G +R S P D+G+ ADL A+ +P P P P
Sbjct: 960 RKEVEAGPGDQQ--GDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAP 1017
Query: 1064 EWEVACPW--GSVGP 1076
+ + P G GP
Sbjct: 1018 RFATSLPHFPGCAGP 1032
>gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]
Length = 1518
Score = 42.4 bits (98), Expect = 0.004
Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 19/135 (14%)
Query: 959 ESVDPGSF----SPQPRPQDTER--PQTLLQMSGSVGSKAADICPLDVEENLTAGKAEIC 1012
+S++P S S PQ+ R P L Q S + + L+ E +T ++ C
Sbjct: 900 DSLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYC 959
Query: 1013 PWEVGAGAGEERALGAEAIRKS---------PNDTGKVSADLGPRERAVTAPEKPQKPTP 1063
EV AG G+++ G +R S P D+G+ ADL A+ +P P P P
Sbjct: 960 RKEVEAGPGDQQ--GDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAP 1017
Query: 1064 EWEVACPW--GSVGP 1076
+ + P G GP
Sbjct: 1018 RFATSLPHFPGCAGP 1032
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 42.4 bits (98), Expect = 0.004
Identities = 47/169 (27%), Positives = 63/169 (37%), Gaps = 13/169 (7%)
Query: 1252 EDGEKTSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPD 1311
EDG +T + P AP D + +R V + GR
Sbjct: 130 EDGPQTQSPRREPAP---NAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKS 186
Query: 1312 AGVYKS--DSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEK---GRAPEKSEPKGVPV 1366
+ + S D S P + P+ G Q G +SQE++ G P +S V
Sbjct: 187 SFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASV 246
Query: 1367 QKKPEMADFRQQ--EAVCPWESQDGKGLSP---QPAPDASDRSRGSSEA 1410
Q PE QQ E+ E K ++P PAP ASDR RG EA
Sbjct: 247 QVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEA 295
Score = 40.0 bits (92), Expect = 0.019
Identities = 127/564 (22%), Positives = 180/564 (31%), Gaps = 116/564 (20%)
Query: 882 QEDLRPEAQEATPAKTEICPWEVNERTREEWTSA----------QVPRG----------G 921
+ED RPE A E + ER+R+E S V R G
Sbjct: 1526 REDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHG 1585
Query: 922 ESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTL 981
E ++++P + ++ +A + P G+ GP + G PR PQ
Sbjct: 1586 EEAVAQDRIPSGKQHQETSACDSPHGED------GPGDFAHTGVPGHVPRSTCAPSPQ-- 1637
Query: 982 LQMSGSVGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKV 1041
E LT +A PW + GE R I + N G
Sbjct: 1638 -------------------REVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQ 1678
Query: 1042 SADLGPRERAVTAPEKPQK---PTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQEL 1098
S P P +P K E E + AC+ D P+AG
Sbjct: 1679 STPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACA------SGDLPEAGTTRT 1732
Query: 1099 DHMGCRPGE-VCPWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQR---EKAL 1154
G+ V P Q+ A S+KA EGT D A + A+++ E+ +
Sbjct: 1733 --FSVVAGDLVLPGSCQDPACSDKA-----PGMEGTAALHGDSPARPQQAKEQPGPERPI 1785
Query: 1155 EKGR----LTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKI--SDLPSSMSSE 1208
G ++S E KL + + R P+ P + D P M
Sbjct: 1786 PAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKV 1845
Query: 1209 VA-EGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPW 1267
+ E E TE + D I Q AP AD E T +S+ V
Sbjct: 1846 TSDETRGAEGTESSPVADD---------IIQPAAP-ADLESPTL---AASSYHGDVVGQV 1892
Query: 1268 ETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCP 1327
T A S+S P ++++ +VS A D A +CP
Sbjct: 1893 STDLIAQSISPA-AAHAGLPPSAAEHIVSPSAPAGD--------------RVEASTPSCP 1937
Query: 1328 WEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVC--PWE 1385
P K +SR EE PE + P P P + + V P
Sbjct: 1938 ------DPAKDLSR----SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPP 1987
Query: 1386 SQDGKGLSPQPAPDA--SDRSRGS 1407
+ G G P PD SD GS
Sbjct: 1988 EEPGCGSETVPVPDGPRSDSVEGS 2011
Score = 38.5 bits (88), Expect = 0.055
Identities = 292/1351 (21%), Positives = 442/1351 (32%), Gaps = 239/1351 (17%)
Query: 273 PALAPTPA--PALAPVPVSPQSPNLLTYICPWENAELPAKQENVPQEGPSGPERGHHSP- 329
P ++P P P AP+ P +E+ E A P E G +P
Sbjct: 198 PGMSPVPLREPMKAPLCGEGDQPG------GFESQEKEAAGGFPPAESRQGVASVQVTPE 251
Query: 330 APARARLWRALSVAVEKS--------------RAGENEMDAEDAHHQREANDVDEDRPKI 375
APA A+ S +EKS RA + E +A Q +D++ R
Sbjct: 252 APAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACH 311
Query: 376 FPKSHSLKAP---VQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAG----E 428
P+S+S AP V S S + A S PE SG +
Sbjct: 312 LPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTID 371
Query: 429 SMGAPSRSPRLGRPKAVSKQAA-------LIPSDDKESLQNQQNAHTSRMLQ-------- 473
G P R +P V AA L S + L + AH + L
Sbjct: 372 VQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIP 431
Query: 474 -VCQREGS--REQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQ 530
+ GS RE + ++ AG GL RQVS ++ E P G
Sbjct: 432 IAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLE--RQVS---DLGSKGEHPEGDP 486
Query: 531 -ELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGNKAEICPWETSE----GAPESRA 585
E+P Q G + ++ + G P E S GAP
Sbjct: 487 GEVPAPSPQERGE-----------HLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPP-P 534
Query: 586 LRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGSAPQ 645
L + P +S ARG P D + V ++ + P +S GG P
Sbjct: 535 LPKAPSES------ARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSP--GGKEEAPEPP 586
Query: 646 D---PGRIR-DKSEAGDSVEARKVEKPGWEAAGPEAHT---PDITKAEPCPWEASEGGED 698
D PG ++ + S+A S +V K +A + P A+P P + G D
Sbjct: 587 DGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQP-PRKGGAGHTD 645
Query: 699 GKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSEC 758
G +Q A D K + P G E P E + G S + + P + +
Sbjct: 646 GPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVP-EGAIWEG-SGLQPKCPDTLQS 703
Query: 759 SGSLGSGIAEVCLW-EAGDAPAIQKAEICPWELDDNVMGQEMLSLGT--GRESLQEKEKA 815
LG + + L E D P AE+ P + + E+ +G+ G L ++
Sbjct: 704 REGLGRMESFLTLESEKSDFPPTPVAEVAP-KAQEGESTLEIRKMGSCDGEGLLTSPDQP 762
Query: 816 SRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSS----SKAGSQFLCN 871
+G + Q A Q E++ + G ++ LD S G ++
Sbjct: 763 --RGPACDASRQEFHAGVPHPPQGENL----AADLGLTALILDQDQQGIPSCPGEGWIRG 816
Query: 872 GGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGESQKDKEKMP 931
S + ++ L+P + + ++ + + TS P + D ++
Sbjct: 817 AASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIH 876
Query: 932 GKSEIEDVTAWEKPEGQIQKQEAVGP--WESVDPGSFSPQPRPQDTERPQTLLQMSGSVG 989
E ++ GQ ++A+G + G+ S P T P ++ S
Sbjct: 877 VPVEPQEDNNLPTHGGQ---EQALGSELQSQLPKGTLSDTP----TSSPTDMVWESS--- 926
Query: 990 SKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGA----EAIRKSPNDTG-----K 1040
L E L+A + P GE+R GA ++ R SP
Sbjct: 927 --------LTEESELSAPTRQKLP-----ALGEKRPEGACGDGQSSRVSPPAADVLKDFS 973
Query: 1041 VSADLGPRERAVTAPEKPQKPTPEWEVACPWGSVGPGACSQHPGTLD-ADG--PKAGFQE 1097
++ + +E T + P K A GS AC +HPG + ADG P G +
Sbjct: 974 LAGNFSRKETCCTG-QGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSK 1032
Query: 1098 LDHMGCRPGEVCPWEAQEAATSEKA----KICPWEVSEGTTGKGLDQKAGSESAEQREKA 1153
+ GE P + A + + P T + +A E+ E R++
Sbjct: 1033 REMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQP 1092
Query: 1154 LEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSEVAEGH 1213
+ QQ+ C W D A++PK L +S S +G
Sbjct: 1093 VP------------------APQQKMEC-WATSD-----AESPK---LLASFPSAGEQGG 1125
Query: 1214 SLEATEKGDL--RQDPKTGSFPEHITQEKAPAA--DTEEFTTEDGEKTSHELQSVCPWE- 1268
A E G DP PE + TE T E ++ L+ C E
Sbjct: 1126 EAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEH 1185
Query: 1269 -------TTAPADSVSHLDRQRPD----QPKASSQRLVSTGGRAADVCPWDV--PDAGVY 1315
PA + + R D Q + L+ +G P +V PD
Sbjct: 1186 PMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSG-------PPEVAAPDTPYL 1238
Query: 1316 KSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSE-PKGVPVQKKPEMAD 1374
DS+A+ E VK VS D RAP +S P G P A
Sbjct: 1239 HVDSAAQ------RGAEDSGVKAVSSAD---------PRAPGESPCPVGEPPLALENAAS 1283
Query: 1375 FRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVA---EVCLWEVVEAPS 1431
+ Q G PA AS S + G V++ L + +A
Sbjct: 1284 LKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATG 1343
Query: 1432 AKKAEICPWEA--------GGGAAEEGEQERESQGQGEMFLQKAGPGGTE---------- 1473
+KA P G AA E E E G+ ++ GG +
Sbjct: 1344 EEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLT 1403
Query: 1474 ------EHFSKAAAKPREQEAVCPGEGTGSG 1498
EH +K KP PGE G+G
Sbjct: 1404 GFPDFREHIAKIFEKPVLGALATPGEKAGAG 1434
>gi|120953251 neuron navigator 3 [Homo sapiens]
Length = 2363
Score = 42.0 bits (97), Expect = 0.005
Identities = 50/194 (25%), Positives = 81/194 (41%), Gaps = 23/194 (11%)
Query: 313 NVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAEDAHHQREANDVDEDR 372
NV +G P+P+ ++ WR+ S+ V+ S + + D +
Sbjct: 308 NVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLK 367
Query: 373 PKIFPKSHSLK-APVQQGSMRSLGLAIKALTRSRSTY----------REKESVEESPE-- 419
P P S +K AP Q SM + A T R ++ ++ ES E
Sbjct: 368 P---PVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEME 424
Query: 420 GQNSG--TAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSR-MLQVCQ 476
G NSG + G + +P SP+L PKA SK S+ K LQ ++ +R +VC
Sbjct: 425 GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNL----SNKKSLLQPKEKEEKNRDKNKVCT 480
Query: 477 REGSREQEDRGRRM 490
+ +E++D+ M
Sbjct: 481 EKPVKEEKDQVTEM 494
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,316,206
Number of Sequences: 37866
Number of extensions: 4352108
Number of successful extensions: 17323
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 413
Number of HSP's that attempted gapping in prelim test: 15367
Number of HSP's gapped (non-prelim): 1766
length of query: 1674
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1558
effective length of database: 13,855,062
effective search space: 21586186596
effective search space used: 21586186596
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.