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Search of human proteins with 239751178
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751178 PREDICTED: basic helix-loop-helix family, member
a9 [Homo sapiens]
(235 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239751178 PREDICTED: basic helix-loop-helix family, member a9... 488 e-138
gi|239745666 PREDICTED: basic helix-loop-helix family, member a9... 488 e-138
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9... 407 e-114
gi|148922889 scleraxis homolog B [Homo sapiens] 67 1e-11
gi|186972126 scleraxis homolog A [Homo sapiens] 67 1e-11
gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 62 3e-10
gi|239752994 PREDICTED: achaete-scute complex homolog 5 (Drosoph... 59 4e-09
gi|239747548 PREDICTED: achaete-scute complex homolog 5 (Drosoph... 59 4e-09
gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo sa... 59 4e-09
gi|90403598 mesoderm posterior 2 homolog [Homo sapiens] 59 4e-09
gi|23097242 nephew of atonal 3 [Homo sapiens] 58 6e-09
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 58 8e-09
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens] 56 3e-08
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 55 4e-08
gi|38455396 neurogenin 1 [Homo sapiens] 54 2e-07
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 53 2e-07
gi|4885075 atonal homolog 1 [Homo sapiens] 52 3e-07
gi|153792190 neurogenic differentiation 4 [Homo sapiens] 52 3e-07
gi|23111009 myogenic differentiation 1 [Homo sapiens] 51 1e-06
gi|121114306 neurogenic differentiation 1 [Homo sapiens] 51 1e-06
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens] 51 1e-06
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 50 2e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens] 49 3e-06
gi|68989258 neurogenin 3 [Homo sapiens] 49 3e-06
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo... 48 8e-06
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens] 47 1e-05
gi|27475985 neurogenic differentiation 6 [Homo sapiens] 47 1e-05
gi|21553337 atonal homolog 7 [Homo sapiens] 47 2e-05
gi|57529222 basic helix-loop-helix domain containing, class B, 4... 46 2e-05
gi|31077092 neurogenin 2 [Homo sapiens] 46 2e-05
>gi|239751178 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 235
Score = 488 bits (1255), Expect = e-138
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 1 MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP 60
MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP
Sbjct: 1 MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP 60
Query: 61 VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV 120
VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV
Sbjct: 61 VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV 120
Query: 121 LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP 180
LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP
Sbjct: 121 LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP 180
Query: 181 PHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS 235
PHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS
Sbjct: 181 PHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS 235
>gi|239745666 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 235
Score = 488 bits (1255), Expect = e-138
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 1 MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP 60
MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP
Sbjct: 1 MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP 60
Query: 61 VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV 120
VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV
Sbjct: 61 VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV 120
Query: 121 LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP 180
LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP
Sbjct: 121 LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP 180
Query: 181 PHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS 235
PHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS
Sbjct: 181 PHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS 235
>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 203
Score = 407 bits (1045), Expect = e-114
Identities = 203/235 (86%), Positives = 203/235 (86%), Gaps = 32/235 (13%)
Query: 1 MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP 60
MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP
Sbjct: 1 MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARP 60
Query: 61 VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV 120
VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV
Sbjct: 61 VRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLV 120
Query: 121 LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP 180
LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP
Sbjct: 121 LRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCP 180
Query: 181 PHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS 235
PH GPPPWPRGYLRSAPGMGHPRS
Sbjct: 181 PH--------------------------------GPPPWPRGYLRSAPGMGHPRS 203
>gi|148922889 scleraxis homolog B [Homo sapiens]
Length = 201
Score = 67.0 bits (162), Expect = 1e-11
Identities = 54/157 (34%), Positives = 66/157 (42%), Gaps = 12/157 (7%)
Query: 20 AEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRA-------RPVRSKARRMAANV 72
+ED G D + A C A AG RRA RP R +R AN
Sbjct: 23 SEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQRHTANA 82
Query: 73 RERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPCG 132
RER R N AF ALR + + ++LSKI TLR A I+ L VL A A CG
Sbjct: 83 RERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEA----CG 138
Query: 133 HLE-CHGPAARGDTGDTGASPPPPAGPSLARPDAARP 168
+ CH A G+ PPPP P + +P
Sbjct: 139 DGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQP 175
>gi|186972126 scleraxis homolog A [Homo sapiens]
Length = 201
Score = 67.0 bits (162), Expect = 1e-11
Identities = 54/157 (34%), Positives = 66/157 (42%), Gaps = 12/157 (7%)
Query: 20 AEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRA-------RPVRSKARRMAANV 72
+ED G D + A C A AG RRA RP R +R AN
Sbjct: 23 SEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQRHTANA 82
Query: 73 RERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPCG 132
RER R N AF ALR + + ++LSKI TLR A I+ L VL A A CG
Sbjct: 83 RERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEA----CG 138
Query: 133 HLE-CHGPAARGDTGDTGASPPPPAGPSLARPDAARP 168
+ CH A G+ PPPP P + +P
Sbjct: 139 DGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQP 175
>gi|30039710 pancreas specific transcription factor, 1a [Homo
sapiens]
Length = 328
Score = 62.4 bits (150), Expect = 3e-10
Identities = 66/180 (36%), Positives = 81/180 (45%), Gaps = 24/180 (13%)
Query: 4 GAPGLGLTARKGAEDSAEDLGGPCP-----EPGGDSGVLGANGASCSRGEAEEPAGRRRA 58
GAP G G+ S L PC PG + + G +GA+ A RR
Sbjct: 105 GAPPGGFPYSPGSPPSC--LAYPCAGAAVLSPG--ARLRGLSGAAA--------AAARRR 152
Query: 59 RPVRSKAR----RMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRI 114
R VRS+A R AANVRER+R+ N+AF LR + KRLSK+ TLR AI I
Sbjct: 153 RRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYI 212
Query: 115 AALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAP 174
LS +++A RG G C GP G G G SP A + R PS P
Sbjct: 213 NFLSELVQADLPLRGG-GAGGCGGPGGGGRLG--GDSPGSQAQKVIICHRGTRSPSPSDP 269
>gi|239752994 PREDICTED: achaete-scute complex homolog 5
(Drosophila) [Homo sapiens]
Length = 313
Score = 58.9 bits (141), Expect = 4e-09
Identities = 42/103 (40%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
Query: 71 NVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGP 130
N RER+R+ NE + LR L L KRLSK+ TLR AI I L +L ++P P
Sbjct: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
Query: 131 CGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSA 173
PA+RG G TG P PPA P RP PS+
Sbjct: 256 --------PASRGLPG-TGPCPAPPATPRPDRPGDGEARAPSS 289
>gi|239747548 PREDICTED: achaete-scute complex homolog 5
(Drosophila) [Homo sapiens]
Length = 313
Score = 58.9 bits (141), Expect = 4e-09
Identities = 42/103 (40%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
Query: 71 NVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGP 130
N RER+R+ NE + LR L L KRLSK+ TLR AI I L +L ++P P
Sbjct: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
Query: 131 CGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSA 173
PA+RG G TG P PPA P RP PS+
Sbjct: 256 --------PASRGLPG-TGPCPAPPATPRPDRPGDGEARAPSS 289
>gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo
sapiens]
Length = 313
Score = 58.9 bits (141), Expect = 4e-09
Identities = 42/103 (40%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
Query: 71 NVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGP 130
N RER+R+ NE + LR L L KRLSK+ TLR AI I L +L ++P P
Sbjct: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
Query: 131 CGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSA 173
PA+RG G TG P PPA P RP PS+
Sbjct: 256 --------PASRGLPG-TGPCPAPPATPRPDRPGDGEARAPSS 289
>gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]
Length = 397
Score = 58.9 bits (141), Expect = 4e-09
Identities = 68/206 (33%), Positives = 85/206 (41%), Gaps = 18/206 (8%)
Query: 19 SAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGR-RRARPVRSKARRMAANVRERKR 77
S+ D G CP G G+ SCS AE A RRAR + +R +A+ RE+ R
Sbjct: 35 SSSDSSGSCPCDGA-RGLPQPQPPSCSSRAAEAAATTPRRARTGPAGGQRQSASEREKLR 93
Query: 78 ILDYNEAFNALRRALRHDL--GGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPCGHLE 135
+ A + LRR L L G+ L+KI TLR AI I LS VL S L+
Sbjct: 94 MRTLARALHELRRFLPPSLAPAGQSLTKIETLRLAIRYIGHLSAVLGLSEE------SLQ 147
Query: 136 CHGPAARGDTGDTGASP-PPPAGPSLARPDAARPSVPSAPRCASCPPHAP-LARPSAVAE 193
C RGD G P P GP+ A+ A +
Sbjct: 148 CR-RRQRGDAGSPWGCPLCPDRGPAEAQTQAEGQGQGQGQGQGQGQGQGQGQGQGQGQGR 206
Query: 194 GPG-----LAQASGGSWRRCPGASSA 214
PG LA+AS GS CPGA +A
Sbjct: 207 RPGLVSAVLAEASWGSPSACPGAQAA 232
>gi|23097242 nephew of atonal 3 [Homo sapiens]
Length = 166
Score = 58.2 bits (139), Expect = 6e-09
Identities = 44/124 (35%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 4 GAPGLGLTARKGAEDSAEDLGGP----CPEPGGDSGVLGANGASCSRGEAEEPAGRRRAR 59
G P L L + + + G P C GD G RG GR + +
Sbjct: 40 GDPALALREGRPRRMARFEEGDPEEEECEVDQGD----GEEEEEEERGRGVSLLGRPKRK 95
Query: 60 PVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSL 119
V + A+R AAN+RERKR+ + NEAF+ LRR + KRLS+I TLR AI I+ ++
Sbjct: 96 RVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTE 155
Query: 120 VLRA 123
+L +
Sbjct: 156 LLES 159
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 57.8 bits (138), Expect = 8e-09
Identities = 48/128 (37%), Positives = 65/128 (50%), Gaps = 6/128 (4%)
Query: 2 LRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRR--RAR 59
LRG G T + E+ +LGG E + G + A R + P R+ +AR
Sbjct: 60 LRGEEGTEATLAEVKEEG--ELGGEEEEEEEEEE--GLDEAEGERPKKRGPKKRKMTKAR 115
Query: 60 PVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSL 119
RSK RR AN RER R+ D N A + LR+ + ++LSKI TLR A + I ALS
Sbjct: 116 LERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSE 175
Query: 120 VLRASPAP 127
+LR+ P
Sbjct: 176 ILRSGKRP 183
Score = 28.5 bits (62), Expect = 5.2
Identities = 13/30 (43%), Positives = 13/30 (43%)
Query: 142 RGDTGDTGASPPPPAGPSLARPDAARPSVP 171
R D GD PPP GP P A VP
Sbjct: 30 RSDKGDAPPPPPPAPGPGAPGPARAAKPVP 59
>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
Length = 193
Score = 55.8 bits (133), Expect = 3e-08
Identities = 54/163 (33%), Positives = 67/163 (41%), Gaps = 26/163 (15%)
Query: 56 RRARPVRSKARRMAA-----NVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRA 110
RR RP ++ AA N RER R+ N F ALR+ + H K+LSK+ TLR A
Sbjct: 36 RRRRPATAETGGGAAAVARRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSA 95
Query: 111 IHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSV 170
+ I AL +L A R A G P P GP P AA PS
Sbjct: 96 VEYIRALQRLLAEHDAVRN----------ALAGGLRPQAVRPSAPRGPPGTTPVAASPS- 144
Query: 171 PSAPRCASCPPHAPLARPSAVAEGPGLAQASGGSWRRCPGASS 213
R +S P + P + P A +S S C GA S
Sbjct: 145 ----RASSSPGRGGSSEPGS----PRSAYSSDDS--GCEGALS 177
>gi|29126247 basic helix-loop-helix family, member a15 [Homo
sapiens]
Length = 189
Score = 55.5 bits (132), Expect = 4e-08
Identities = 55/168 (32%), Positives = 69/168 (41%), Gaps = 24/168 (14%)
Query: 3 RGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEE-------PAGR 55
R AP A G L P PEP A A+ + GE P GR
Sbjct: 10 RRAPVQDTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAAARAPGEGRRRRPGPSGPGGR 69
Query: 56 RRARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIA 115
R + S RR+ +N RER+R+ N AF ALR + H K+LSKI TL A + I
Sbjct: 70 RDS----SIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIK 125
Query: 116 ALSLVLRASPAPRGPCGHLECHGP-----------AARGDTGDTGASP 152
+L+ + + R P LE GP A G G T A P
Sbjct: 126 SLTATILTMSSSRLP--GLEGPGPKLYQHYQQQQQVAGGALGATEAQP 171
>gi|38455396 neurogenin 1 [Homo sapiens]
Length = 237
Score = 53.5 bits (127), Expect = 2e-07
Identities = 53/189 (28%), Positives = 75/189 (39%), Gaps = 30/189 (15%)
Query: 17 EDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKA--------RRM 68
+ +A G P P G + A+ ++ + +E RR VRS+A RR+
Sbjct: 36 QQAASASGPPAPARRGAPNISRASEVPGAQDDEQERRRRRGRTRVRSEALLHSLRRSRRV 95
Query: 69 AANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRAS---- 124
AN RER R+ + N A +ALR L +L+KI TLR A + I AL+ LR +
Sbjct: 96 KANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGL 155
Query: 125 ------------------PAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAA 166
P P P E G A + + S P + RP
Sbjct: 156 PGGGARERLLPPQCVPCLPGPPSPASDAESWGSGAAAASPLSDPSSPAASEDFTYRPGDP 215
Query: 167 RPSVPSAPR 175
S PS P+
Sbjct: 216 VFSFPSLPK 224
>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
sapiens]
Length = 323
Score = 53.1 bits (126), Expect = 2e-07
Identities = 60/213 (28%), Positives = 83/213 (38%), Gaps = 19/213 (8%)
Query: 23 LGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKAR-------RMAANVRER 75
+G PG G G +S S + A + + + R+ N RER
Sbjct: 59 MGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRER 118
Query: 76 KRILDYNEAFNALRRAL--RHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPC-- 131
KR+ D N A + LR + H ++LSKIATL A + I L+ L
Sbjct: 119 KRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYG 178
Query: 132 GHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSV--PSAPRCASCPPHAPLARPS 189
GH P+A G + P A P+ A A P+V P P A+ A A
Sbjct: 179 GHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAV 238
Query: 190 AVAEGPGLAQASGGSWR------RCPGASSAGP 216
+ A PG S GS R + P A++A P
Sbjct: 239 SSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAP 271
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 52.4 bits (124), Expect = 3e-07
Identities = 43/124 (34%), Positives = 55/124 (44%), Gaps = 8/124 (6%)
Query: 64 KARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRA 123
K RR+AAN RER+R+ N AF+ LR + K+LSK TL+ A I ALS +L+
Sbjct: 158 KQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQT 217
Query: 124 ------SPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCA 177
P P C H A G GA AG A + RP+ P + R
Sbjct: 218 PSGGEQPPPPPASCKSDHHHLRTAASYEG--GAGNATAAGAQQASGGSQRPTPPGSCRTR 275
Query: 178 SCPP 181
P
Sbjct: 276 FSAP 279
>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
Length = 331
Score = 52.4 bits (124), Expect = 3e-07
Identities = 33/73 (45%), Positives = 43/73 (58%)
Query: 57 RARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAA 116
+AR R +ARR+ AN RER R+ N+A + LRR + ++LSKI TLR A + I A
Sbjct: 79 KARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWA 138
Query: 117 LSLVLRASPAPRG 129
LS VL P G
Sbjct: 139 LSEVLETGQTPEG 151
>gi|23111009 myogenic differentiation 1 [Homo sapiens]
Length = 320
Score = 50.8 bits (120), Expect = 1e-06
Identities = 57/183 (31%), Positives = 72/183 (39%), Gaps = 11/183 (6%)
Query: 59 RPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALS 118
R + RR AA +RER+R+ NEAF L+R + +RL K+ LR AI I L
Sbjct: 103 RKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSN-PNQRLPKVEILRNAIRYIEGLQ 161
Query: 119 LVLR-ASPAPRGPCGHLECHGPAARGD-----TGDTGASPPPPAGPSLARPDAARPSVPS 172
+LR AP G GP G +GD+ AS P + S D + P PS
Sbjct: 162 ALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDAS-SPRSNCSDGMMDYSGP--PS 218
Query: 173 APRCASCPPHAPL-ARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMG 231
R +C A PS G A +S S P P L P
Sbjct: 219 GARRRNCYEGAYYNEAPSEPRPGKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSES 278
Query: 232 HPR 234
PR
Sbjct: 279 PPR 281
>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
Length = 356
Score = 50.8 bits (120), Expect = 1e-06
Identities = 32/71 (45%), Positives = 43/71 (60%)
Query: 57 RARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAA 116
+AR R K RRM AN RER R+ N A + LR+ + ++LSKI TLR A + I A
Sbjct: 93 KARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWA 152
Query: 117 LSLVLRASPAP 127
LS +LR+ +P
Sbjct: 153 LSEILRSGKSP 163
>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
Length = 271
Score = 50.8 bits (120), Expect = 1e-06
Identities = 66/205 (32%), Positives = 85/205 (41%), Gaps = 34/205 (16%)
Query: 5 APGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSK 64
AP L AR+ E AE P P PG GA+ +R +A+E ++ R + S
Sbjct: 62 APLLPKAAREKPEAPAEP---PGPGPGS-----GAHPGGSARPDAKEEQQQQLRRKINS- 112
Query: 65 ARRMAANVRERKRILDYNEAFNALRRAL-----RHDLG--GKRLSKIATLRRAIHRI--- 114
RERKR+ D N A +ALR + H G G++LSKIATL A + I
Sbjct: 113 --------RERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLL 164
Query: 115 -AALSLVLRASPAPRGPCG-HLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPS 172
++L + RA GP L G + P GP PDA RP+
Sbjct: 165 GSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGP----PDALRPA-KY 219
Query: 173 APRCASCPPHAPLARPSAVAEGPGL 197
PP A P A GPGL
Sbjct: 220 LSLALDEPPCGQFALPGGGAGGPGL 244
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 50.1 bits (118), Expect = 2e-06
Identities = 41/119 (34%), Positives = 54/119 (45%), Gaps = 14/119 (11%)
Query: 3 RGAPGLGLTARKGAE--DSAEDLGGPCPEPGG---------DSGVLGANGASCS-RGEAE 50
R +PG G K AE +A GG PGG SG G G S S G +
Sbjct: 168 RASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSS 227
Query: 51 EPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRAL--RHDLGGKRLSKIATL 107
+ + KA R+ N RER+R+ D N+A + LR + H ++LSKIATL
Sbjct: 228 SSSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATL 286
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 49.3 bits (116), Expect = 3e-06
Identities = 45/132 (34%), Positives = 54/132 (40%), Gaps = 24/132 (18%)
Query: 101 LSKIATLRRAIHRIA-ALSLVLRASPAPRGPCGHLECHGPAARGDTGDTG---------- 149
L+ A L + H A A+SLV GP L PAA G T
Sbjct: 198 LNGSAALLNSHHAAAPAVSLV------NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA 251
Query: 150 -ASPPPPAGPSLARPDAARPSVPSAPRCASCPPHAPLARPSAVAEGPGLAQASGGSWRRC 208
A+P PPA P+ A P AA P P AP + PP P P+A P A A G
Sbjct: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG----- 306
Query: 209 PGASSAGPPPWP 220
G++ A P P P
Sbjct: 307 -GSAGAAPAPAP 317
Score = 45.8 bits (107), Expect = 3e-05
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 22/118 (18%)
Query: 123 ASPAPRGPCGHLECHGPAARGDTGDTGASPPPP-AGPSLARPDAARPSVPSAPRCA--SC 179
A PAP P PAA A PPPP A +LARP P P+ P A +
Sbjct: 248 APPAPAAPSP------PAAPAPAAPAAAPPPPPPAPATLARP----PGHPAGPPTAAPAV 297
Query: 180 PPHAPLARPSAVAEGPGLAQASGG----SWRRCPGASSAGPPPW-----PRGYLRSAP 228
PP A + P A A+GG S + PGA++A P P P+ +++AP
Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAP 355
Score = 43.1 bits (100), Expect = 2e-04
Identities = 52/171 (30%), Positives = 66/171 (38%), Gaps = 37/171 (21%)
Query: 95 DLGGKRLSKIATLRRAIHRIAALSLVLRASPA-----------PRGPCGHLECHGPAARG 143
DL G S++A H +A + +RA+ A P G G GPAA
Sbjct: 24 DLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGA----GPAAPA 79
Query: 144 DTGDTGASPPPPAGPSL---------ARPDAARPSVPSAPRCASC----PPH------AP 184
+ A PPPAG + P RP VP+ P + PP AP
Sbjct: 80 EGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP 139
Query: 185 LARPSAVAEGPGLAQASGGSWRRCPG--ASSAGPPPWPRGYLRSAPGMGHP 233
+ +AVA GP A A G + P A+ AGP P P PG G P
Sbjct: 140 VPAAAAVAAGPEPAPA-GPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP 189
Score = 36.2 bits (82), Expect = 0.025
Identities = 46/157 (29%), Positives = 53/157 (33%), Gaps = 49/157 (31%)
Query: 115 AALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPP----------PAGPSLARP- 163
AA ++ PAP GP + GPAA G P P PAGP A+
Sbjct: 142 AAAAVAAGPEPAPAGPA---KPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTL 198
Query: 164 ----------DAARPSV---------------PSAPRCA-SCPPHAPLARPSA-VAEGPG 196
AA P+V P+AP PP A P A A P
Sbjct: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPP 258
Query: 197 LAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHP 233
A A P A +A PPP P A GHP
Sbjct: 259 AAPA--------PAAPAAAPPPPPPAPATLARPPGHP 287
Score = 28.1 bits (61), Expect = 6.8
Identities = 21/62 (33%), Positives = 24/62 (38%), Gaps = 2/62 (3%)
Query: 173 APRCASCPPHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGH 232
APR A A + V G A G GA A P P P G R+ PG G
Sbjct: 44 APRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAG--RARPGGGG 101
Query: 233 PR 234
P+
Sbjct: 102 PQ 103
>gi|68989258 neurogenin 3 [Homo sapiens]
Length = 214
Score = 49.3 bits (116), Expect = 3e-06
Identities = 60/189 (31%), Positives = 79/189 (41%), Gaps = 29/189 (15%)
Query: 10 LTARKGAEDSAEDLGGPCPEP--GGDSGV---LGANGASCSRGEAEEPAGRRRARPVRSK 64
+T A S G C E GG G L A SR ++E ++R +
Sbjct: 29 VTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQR------R 82
Query: 65 ARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRAS 124
+RR AN RER R+ + N A +ALR L +L+KI TLR A + I AL+ LR +
Sbjct: 83 SRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIA 142
Query: 125 ---------PAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAA---RPSVPS 172
PAP CG L G G GD G+ P + P A+ RP +
Sbjct: 143 DHSLYALEPPAPH--CGELGSPG----GSPGDWGSLYSPVSQAGSLSPAASLEERPGLLG 196
Query: 173 APRCASCPP 181
A A P
Sbjct: 197 ATFSACLSP 205
>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
sapiens]
Length = 199
Score = 47.8 bits (112), Expect = 8e-06
Identities = 41/109 (37%), Positives = 48/109 (44%), Gaps = 8/109 (7%)
Query: 52 PAGRRRAR------PVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIA 105
P G RRA PV +R AAN RER R N AF ALR + + ++LSKI
Sbjct: 53 PGGGRRAGGGGGAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIE 112
Query: 106 TLRRAIHRIAALS--LVLRASPAPRGPCGHLECHGPAARGDTGDTGASP 152
TLR A IA L+ L+L S PC A D G P
Sbjct: 113 TLRLASSYIAHLANVLLLGDSADDGQPCFRAAGSAKGAVPAAADGGRQP 161
>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
Length = 272
Score = 47.0 bits (110), Expect = 1e-05
Identities = 61/208 (29%), Positives = 84/208 (40%), Gaps = 29/208 (13%)
Query: 30 PGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALR 89
PG GA A GE+ + +++ + R+ N RERKR+ D N A + LR
Sbjct: 52 PGESLSRAGAKAA----GESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLR 107
Query: 90 RAL--RHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPC--GHLECHGPAARGDT 145
+ H ++LSKIATL A + I L+ L G GH H G
Sbjct: 108 EVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGH---HSAFHCGTV 164
Query: 146 GDTGASPP----------PPAGPSLARPDAARP-SVPSAPRCASC-PPHAPLARPS---A 190
G + P P G +L+ +A+ P S S P + PPH+ L PS A
Sbjct: 165 GHSAGHPAHAANSVHPVHPILGGALSSGNASSPLSAASLPAIGTIRPPHSLLKAPSTPPA 224
Query: 191 VAEGPGLAQASGGSWRRCPGASSAGPPP 218
+ G G +G CP PPP
Sbjct: 225 LQLGSGFQHWAG---LPCPCTICQMPPP 249
>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
Length = 337
Score = 47.0 bits (110), Expect = 1e-05
Identities = 34/88 (38%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Query: 40 NGASCSRGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGK 99
NG RG ++ + R R K RR AN RER R+ N+A + LR+ + +
Sbjct: 71 NGLPRRRGLRKKKTTKLRLE--RVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQ 128
Query: 100 RLSKIATLRRAIHRIAALSLVLRASPAP 127
+LSKI TLR A + I ALS +LR P
Sbjct: 129 KLSKIETLRLAKNYIWALSEILRIGKRP 156
>gi|21553337 atonal homolog 7 [Homo sapiens]
Length = 152
Score = 46.6 bits (109), Expect = 2e-05
Identities = 26/56 (46%), Positives = 36/56 (64%)
Query: 66 RRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVL 121
RR+AAN RER+R+ N AF+ LRR + K+LSK TL+ A+ I AL+ +L
Sbjct: 41 RRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRIL 96
>gi|57529222 basic helix-loop-helix domain containing, class B, 4
[Homo sapiens]
Length = 225
Score = 46.2 bits (108), Expect = 2e-05
Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 12/136 (8%)
Query: 46 RGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRAL--RHDLGGKRLSK 103
RG GRRR R RS R++ N RER+R+ D N+A + LR + H ++LSK
Sbjct: 83 RGPGSAADGRRRPREQRSL--RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140
Query: 104 IATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARP 163
IATL + A + +L + A L +G A+P P G + P
Sbjct: 141 IATL------LLAKNYILMQAQA-LDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCP 193
Query: 164 DAARPSV-PSAPRCAS 178
+A ++ P +CA+
Sbjct: 194 FSAGAALGPCPDKCAA 209
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 46.2 bits (108), Expect = 2e-05
Identities = 65/229 (28%), Positives = 86/229 (37%), Gaps = 50/229 (21%)
Query: 4 GAPGLGLTARKGAEDSAEDLGGPCPEPGG--DSGVLGANGASCSRGEAEEPAGRRRARPV 61
GA G G ++GAE GG G + +LG C R + A R A+
Sbjct: 46 GASG-GARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVH-DCKRRPSRARAVSRGAKTA 103
Query: 62 RS-----KARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAA 116
+ K RR+ AN RER R+ + N A +ALR L +L+KI TLR A + I A
Sbjct: 104 ETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWA 163
Query: 117 LSLVLRASP--------------------APRGPCGHLECHG--------------PAAR 142
L+ LR + +P G L G PA
Sbjct: 164 LTETLRLADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPS 223
Query: 143 GDTGDTGASP----PPPAGPSLARPDAARPSVPSAPRCASCPPHAPLAR 187
SP PA P+ + D +P P R A PH P+AR
Sbjct: 224 SSVSSNSTSPYSCTLSPASPAGSDMDYWQPPPPDKHRYA---PHLPIAR 269
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,541,396
Number of Sequences: 37866
Number of extensions: 894688
Number of successful extensions: 11455
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 305
Number of HSP's successfully gapped in prelim test: 1167
Number of HSP's that attempted gapping in prelim test: 7483
Number of HSP's gapped (non-prelim): 4363
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.