Guide to the Human Genome
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Search of human proteins with 239750776

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r...   479   e-135
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r...   452   e-128
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r...   452   e-127
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r...   448   e-126
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]   442   e-125
gi|5453680 neural precursor cell expressed, developmentally down...   134   5e-32
gi|215422375 neural precursor cell expressed, developmentally do...   132   2e-31
gi|78486553 neural precursor cell expressed, developmentally dow...   125   3e-29
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...   113   1e-25
gi|55769585 HEF-like protein [Homo sapiens]                            89   2e-18
gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]               65   4e-11
gi|11321634 CD2-associated protein [Homo sapiens]                      58   7e-09
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    56   2e-08
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    56   2e-08
gi|224177511 sorting nexin 18 isoform c [Homo sapiens]                 56   3e-08
gi|157057545 sorting nexin 18 isoform a [Homo sapiens]                 56   3e-08
gi|157057543 sorting nexin 18 isoform b [Homo sapiens]                 56   3e-08
gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]                54   1e-07
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H...    53   2e-07
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H...    53   2e-07
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       52   4e-07
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       52   4e-07
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       52   4e-07
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        52   4e-07
gi|20149528 proline-serine-threonine phosphatase interacting pro...    52   4e-07
gi|155723000 mixed lineage kinase 4 [Homo sapiens]                     52   5e-07
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    51   9e-07
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    51   9e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    50   2e-06
gi|27544941 myosin IF [Homo sapiens]                                   49   3e-06

>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 224

 Score =  479 bits (1232), Expect = e-135
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
           MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKVRLSWHSRAAPQV 224
           VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKVRLSWHSRAAPQV
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKVRLSWHSRAAPQV 224


>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 232

 Score =  452 bits (1164), Expect = e-128
 Identities = 212/215 (98%), Positives = 212/215 (98%)

Query: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
           MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKVRLS 215
           VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK   S
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKANPS 215


>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 368

 Score =  452 bits (1163), Expect = e-127
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
           MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
           VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211


>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 353

 Score =  448 bits (1153), Expect = e-126
 Identities = 209/211 (99%), Positives = 210/211 (99%)

Query: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
           MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGI+PGNHL
Sbjct: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
           VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211


>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
          Length = 870

 Score =  442 bits (1138), Expect = e-125
 Identities = 207/212 (97%), Positives = 207/212 (97%)

Query: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
           MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGN L
Sbjct: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAP PPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV PGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKV 212
           VPPSAGMGHDIYQVP SMDTRSWEGTKPPAKV
Sbjct: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKV 212



 Score = 36.6 bits (83), Expect = 0.018
 Identities = 39/138 (28%), Positives = 54/138 (39%), Gaps = 30/138 (21%)

Query: 66  MYDKKPA---GP-GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPS 121
           +YD  P    GP G  P        P +   +PP++ +       Y   P     VP   
Sbjct: 266 VYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHA-----VYDVPPSVSKDVPDGP 320

Query: 122 KAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGP-AQDIYQ 180
             ++  Y VP         PA     F+K  P  P  +P   L   +P P  P A+D+Y 
Sbjct: 321 LLREETYDVP---------PA-----FAKAKPFDPARTP---LVLAAPPPDSPPAEDVYD 363

Query: 181 VPPSAGMGHDIYQVPSSM 198
           VPP A    D+Y VP  +
Sbjct: 364 VPPPA---PDLYDVPPGL 378



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 35/151 (23%), Positives = 56/151 (37%), Gaps = 25/151 (16%)

Query: 78  PPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVP-----TPSKA-----QQGL 127
           PP +P  P   ++   PPA     + P   +P P ++Y VP      P  A       G+
Sbjct: 352 PPDSP--PAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGV 409

Query: 128 YQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDI--------- 178
           Y VP P+ +      K+ S  S  +      + + ++     GPG    ++         
Sbjct: 410 YAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEV----AGPGREPLELEVAVEALAR 465

Query: 179 YQVPPSAGMGHDIYQVPSSMDTRSWEGTKPP 209
            Q   SA + H +    S+  T SW     P
Sbjct: 466 LQQGVSATVAHLLDLAGSAGATGSWRSPSEP 496


>gi|5453680 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 1 [Homo sapiens]
          Length = 834

 Score =  134 bits (338), Expect = 5e-32
 Identities = 86/217 (39%), Positives = 116/217 (53%), Gaps = 35/217 (16%)

Query: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
           M + N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +
Sbjct: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           K+L+        GP     ++  QP  GL        Q    +PN      D++Y VP P
Sbjct: 61  KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110

Query: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPS 159
           S   QG+YQVP   G   Q  +Q PP+ Q S      PH                + +PS
Sbjct: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS 170

Query: 160 P-ATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195
               D+Y +   P    Q +Y +PPS+  G  ++ VP
Sbjct: 171 RYQKDVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 17/103 (16%)

Query: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141
           P+    G++  +PP+S   P            V+ VP      QG+Y +P     +  PP
Sbjct: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227

Query: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPS 184
           +        +   + FP P     +    P G    +Y +PP+
Sbjct: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPT 266


>gi|215422375 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 3 [Homo sapiens]
          Length = 834

 Score =  132 bits (333), Expect = 2e-31
 Identities = 85/213 (39%), Positives = 114/213 (53%), Gaps = 35/213 (16%)

Query: 5   NVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILV 64
           N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +K+L+
Sbjct: 5   NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64

Query: 65  GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
                   GP     ++  QP  GL        Q    +PN      D++Y VP PS   
Sbjct: 65  --------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-PSYQN 114

Query: 125 QGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPSP-AT 162
           QG+YQVP   G   Q  +Q PP+ Q S      PH                + +PS    
Sbjct: 115 QGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQK 174

Query: 163 DLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195
           D+Y +   P    Q +Y +PPS+  G  ++ VP
Sbjct: 175 DVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 17/103 (16%)

Query: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141
           P+    G++  +PP+S   P            V+ VP      QG+Y +P     +  PP
Sbjct: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227

Query: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPS 184
           +        +   + FP P     +    P G    +Y +PP+
Sbjct: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPT 266


>gi|78486553 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 2 [Homo sapiens]
          Length = 174

 Score =  125 bits (314), Expect = 3e-29
 Identities = 73/159 (45%), Positives = 94/159 (59%), Gaps = 15/159 (9%)

Query: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
           M + N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +
Sbjct: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           K+L+        GP     ++  QP  GL        Q    +PN      D++Y VP P
Sbjct: 61  KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110

Query: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH 154
           S   QG+YQVP   G   Q  +Q PP+ Q S      PH
Sbjct: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPH 149


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score =  113 bits (283), Expect = 1e-25
 Identities = 84/231 (36%), Positives = 110/231 (47%), Gaps = 42/231 (18%)

Query: 7   LAKALYVNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
           LA+ALY N AESP ELSFR+GD++ VL+++   GLDGW LCSLHG+QGIVP N +K+L  
Sbjct: 9   LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66

Query: 66  MYDKKPAGPGPGPPATPAQP-QPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
                PAGP P P  +PA P QPG   P P  S            +   VY+VP P++  
Sbjct: 67  -----PAGPAPKPSLSPASPAQPGSPYPAPDHSN-----------EDQEVYVVPPPARPC 110

Query: 125 QGLYQVPGPSPQ-----FQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIY 179
                  GP P      ++ P A  T   + +     +  P T L   S GP       Y
Sbjct: 111 PTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGP-------Y 163

Query: 180 QVPPSAGMGHDIYQV---PSSMDTRSWE---GTKPPAKVR--LSWHSRAAP 222
             P  A   H + +V   P   D   ++     KPPA++   L W     P
Sbjct: 164 DCP--ASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREP 212


>gi|55769585 HEF-like protein [Homo sapiens]
          Length = 786

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 66/194 (34%), Positives = 89/194 (45%), Gaps = 22/194 (11%)

Query: 6   VLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
           +LA+ALY N  +  DEL+F +GDI+T+LEQ     +GWW C LHGRQG+ P N L+IL  
Sbjct: 14  LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73

Query: 66  MYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
           +   +P  P   G    PA  +     P  P     P  P     Q  S    P P  AQ
Sbjct: 74  VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129

Query: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVSPGPGGPA-- 175
             +Y+ P P P       ++T +F KQ   T   P     P+  + +Y V     GP   
Sbjct: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVL 186

Query: 176 -----QDIYQVPPS 184
                Q +Y +P S
Sbjct: 187 KEPEKQQLYDIPAS 200


>gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]
          Length = 740

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 49/158 (31%), Positives = 73/158 (46%), Gaps = 12/158 (7%)

Query: 9   KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
           KALY    ++ DELSF +G I+ +L ++ Q  DG+W    +GR G+ P     +LV    
Sbjct: 573 KALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVFP----SVLVEELS 628

Query: 69  KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPD---SVYLVPTPSKAQQ 125
               G  P        P P  HA +PP   Y    P++  P PD   S+Y   +PS  ++
Sbjct: 629 ASENGDTPWMREIQISPSPKPHASLPPLPLY-DQPPSSPYPSPDKRSSLYFPRSPSANEK 687

Query: 126 GLY-QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPAT 162
            L+ + PG S   +  P    +++ K  P    P P T
Sbjct: 688 SLHAESPGFSQASRHTP---ETSYGKLRPVRAAPPPPT 722


>gi|11321634 CD2-associated protein [Homo sapiens]
          Length = 639

 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 20/159 (12%)

Query: 9   KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
           + L+     + DEL+F++G+I+ ++ ++T G  GWW   L+G++G+ P N   + +   D
Sbjct: 275 RTLFAYEGTNEDELTFKEGEIIHLISKET-GEAGWWRGELNGKEGVFPDN-FAVQINELD 332

Query: 69  KK-PAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGL 127
           K  P    P PPA    P+P L   +    +Y  + P   + + +   L   PSK     
Sbjct: 333 KDFPKPKKPPPPAKAPAPKPEL---IAAEKKYFSLKP---EEKDEKSTLEQKPSKP---- 382

Query: 128 YQVPGPSPQFQSPPAK------QTSTFSKQTPHHPFPSP 160
              P   P+  +PP K       + T   + P  P P P
Sbjct: 383 -AAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPP 420



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 3/55 (5%)

Query: 9   KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKIL 63
           K L+  + ++ DEL  + GDI+ + E+  +G   WW  +L+ + G+ P N +K L
Sbjct: 114 KVLFEYIPQNEDELELKVGDIIDINEEVEEG---WWSGTLNNKLGLFPSNFVKEL 165



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 2/42 (4%)

Query: 20 DELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLK 61
          DEL+ R G+I+  +++  +  +GW    L+GR+G+ P N +K
Sbjct: 16 DELTIRVGEIIRNVKKLQE--EGWLEGELNGRRGMFPDNFVK 55


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 2/79 (2%)

Query: 9   KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
           K ++   A++ DEL+ ++GDI+T++ +D   + GWW   L+GR+G+ P N +K+L   ++
Sbjct: 236 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFE 294

Query: 69  KKPAGP-GPGPPATPAQPQ 86
           K+   P  P PP+ P   Q
Sbjct: 295 KEGNRPKKPPPPSAPVIKQ 313



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 17  ESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYDK 69
           ++ DEL  + GDI+ V+ +  +G   WW   L+G+ G+ P N +K L G  D+
Sbjct: 75  QNDDELELKVGDIIEVVGEVEEG---WWEGVLNGKTGMFPSNFIKELSGESDE 124


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 2/79 (2%)

Query: 9   KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
           K ++   A++ DEL+ ++GDI+T++ +D   + GWW   L+GR+G+ P N +K+L   ++
Sbjct: 273 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFE 331

Query: 69  KKPAGP-GPGPPATPAQPQ 86
           K+   P  P PP+ P   Q
Sbjct: 332 KEGNRPKKPPPPSAPVIKQ 350



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 17  ESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYDK 69
           ++ DEL  + GDI+ V+ +  +G   WW   L+G+ G+ P N +K L G  D+
Sbjct: 112 QNDDELELKVGDIIEVVGEVEEG---WWEGVLNGKTGMFPSNFIKELSGESDE 161



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 3/56 (5%)

Query: 16 AESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYDKKP 71
          A+  DEL+   G+I+T + ++     GWW   ++GR+G+ P N ++ +     K P
Sbjct: 12 AQHDDELTISVGEIITNIRKED---GGWWEGQINGRRGLFPDNFVREIKKEMKKDP 64


>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
          Length = 591

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)

Query: 8   AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64
           A+ALY   +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60

Query: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113

Query: 124 -QQGLYQVPG-----------PSPQ 136
                +Q PG           PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138


>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
          Length = 624

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)

Query: 8   AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64
           A+ALY   +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60

Query: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113

Query: 124 -QQGLYQVPG-----------PSPQ 136
                +Q PG           PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138


>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
          Length = 628

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)

Query: 8   AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64
           A+ALY   +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60

Query: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113

Query: 124 -QQGLYQVPG-----------PSPQ 136
                +Q PG           PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138


>gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]
          Length = 690

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 43/153 (28%), Positives = 69/153 (45%), Gaps = 15/153 (9%)

Query: 7   LAKALYVNVAESPDELSFRKGDIMTVLEQDTQGL-DGWWLCSLHGRQGIVPGNHLKILVG 65
           LA+ALY    +S +ELSF +G ++ +L +   G+ DG+W     GR G+ P   ++ L+G
Sbjct: 550 LAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFPSLLVEELLG 609

Query: 66  MYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQ 125
                     PGPP   + P+  L +P PP+  ++P  P +    P +  L    +    
Sbjct: 610 ---------PPGPPEL-SDPEQMLPSPSPPS--FSPPAPTSVLDGPPAPVLPGDKALDFP 657

Query: 126 GLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFP 158
           G   +  P  +   PP    +      P HP P
Sbjct: 658 GFLDMMAPRLRPMRPPPPPPA--KAPDPGHPDP 688


>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 34/161 (21%)

Query: 9   KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
           + L+    E+PDEL+ R+GD++ VL + T+   GWW     GR+G+ P N +        
Sbjct: 187 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 238

Query: 69  KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQ----------PDSVYLVP 118
                  P PP     P+  +     P  +   ++P T  P           P       
Sbjct: 239 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 291

Query: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTSTFSKQTP 153
           TPS+  Q L  +  GP+  FQS     P  K++ T   QTP
Sbjct: 292 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKT---QTP 329



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 22/112 (19%)

Query: 13  VNVAESP---DELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYDK 69
           VN + SP   DEL  + G+I+ ++++     DGWWL   +G+ G  P N +++L    D 
Sbjct: 90  VNFSYSPEQADELKLQAGEIVEMIKEIE---DGWWLGKKNGQLGAFPSNFVELL----DS 142

Query: 70  KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPN-TYQPQPDSVYLVPTP 120
            P  P  G P  P+         V P  Q  P L +  Y   PD +  V  P
Sbjct: 143 GP--PSLGNPDMPS---------VSPGPQRPPKLSSLAYDSPPDYLQTVSHP 183


>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
           sapiens]
          Length = 645

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 34/161 (21%)

Query: 9   KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
           + L+    E+PDEL+ R+GD++ VL + T+   GWW     GR+G+ P N +        
Sbjct: 76  RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 127

Query: 69  KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQ----------PDSVYLVP 118
                  P PP     P+  +     P  +   ++P T  P           P       
Sbjct: 128 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 180

Query: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTSTFSKQTP 153
           TPS+  Q L  +  GP+  FQS     P  K++ T   QTP
Sbjct: 181 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKT---QTP 218



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 16/81 (19%)

Query: 41  DGWWLCSLHGRQGIVPGNHLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYT 100
           DGWWL   +G+ G  P N +++L    D  P  P  G P  P+         V P  Q  
Sbjct: 7   DGWWLGKKNGQLGAFPSNFVELL----DSGP--PSLGNPDMPS---------VSPGPQRP 51

Query: 101 PMLPN-TYQPQPDSVYLVPTP 120
           P L +  Y   PD +  V  P
Sbjct: 52  PKLSSLAYDSPPDYLQTVSHP 72


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 51/147 (34%), Positives = 61/147 (41%), Gaps = 18/147 (12%)

Query: 75  GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS 134
           G   P TP  P P      P  +  TP  P  Y     S Y  P+P    QG YQ P PS
Sbjct: 849 GTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSP----QGSYQ-PSPS 903

Query: 135 P----QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVP--PSAGMG 188
           P    Q    PA   +T S  + +HP PSP    YQ SP P  P       P  PS G G
Sbjct: 904 PQSYHQVAPSPAGYQNTHSPAS-YHPTPSPMA--YQASPSP-SPVGYSPMTPGAPSPG-G 958

Query: 189 HDIYQVPSSMDTRS--WEGTKPPAKVR 213
           ++ +   S ++  S  W  T    KVR
Sbjct: 959 YNPHTPGSGIEQNSSDWVTTDIQVKVR 985


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 51/147 (34%), Positives = 61/147 (41%), Gaps = 18/147 (12%)

Query: 75  GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS 134
           G   P TP  P P      P  +  TP  P  Y     S Y  P+P    QG YQ P PS
Sbjct: 853 GTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSP----QGSYQ-PSPS 907

Query: 135 P----QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVP--PSAGMG 188
           P    Q    PA   +T S  + +HP PSP    YQ SP P  P       P  PS G G
Sbjct: 908 PQSYHQVAPSPAGYQNTHSPAS-YHPTPSPMA--YQASPSP-SPVGYSPMTPGAPSPG-G 962

Query: 189 HDIYQVPSSMDTRS--WEGTKPPAKVR 213
           ++ +   S ++  S  W  T    KVR
Sbjct: 963 YNPHTPGSGIEQNSSDWVTTDIQVKVR 989


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 51/147 (34%), Positives = 61/147 (41%), Gaps = 18/147 (12%)

Query: 75  GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS 134
           G   P TP  P P      P  +  TP  P  Y     S Y  P+P    QG YQ P PS
Sbjct: 853 GTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSP----QGSYQ-PSPS 907

Query: 135 P----QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVP--PSAGMG 188
           P    Q    PA   +T S  + +HP PSP    YQ SP P  P       P  PS G G
Sbjct: 908 PQSYHQVAPSPAGYQNTHSPAS-YHPTPSPMA--YQASPSP-SPVGYSPMTPGAPSPG-G 962

Query: 189 HDIYQVPSSMDTRS--WEGTKPPAKVR 213
           ++ +   S ++  S  W  T    KVR
Sbjct: 963 YNPHTPGSGIEQNSSDWVTTDIQVKVR 989


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 51/147 (34%), Positives = 61/147 (41%), Gaps = 18/147 (12%)

Query: 75  GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS 134
           G   P TP  P P      P  +  TP  P  Y     S Y  P+P    QG YQ P PS
Sbjct: 853 GTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSP----QGSYQ-PSPS 907

Query: 135 P----QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVP--PSAGMG 188
           P    Q    PA   +T S  + +HP PSP    YQ SP P  P       P  PS G G
Sbjct: 908 PQSYHQVAPSPAGYQNTHSPAS-YHPTPSPMA--YQASPSP-SPVGYSPMTPGAPSPG-G 962

Query: 189 HDIYQVPSSMDTRS--WEGTKPPAKVR 213
           ++ +   S ++  S  W  T    KVR
Sbjct: 963 YNPHTPGSGIEQNSSDWVTTDIQVKVR 989


>gi|20149528 proline-serine-threonine phosphatase interacting
           protein 1 [Homo sapiens]
          Length = 416

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 24/55 (43%), Positives = 36/55 (65%), Gaps = 3/55 (5%)

Query: 9   KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKIL 63
           +ALY   A++PDEL    GDI+ V+    +G DGWW    +G++G VPG++L+ L
Sbjct: 365 RALYDYTAQNPDELDLSAGDILEVI---LEGEDGWWTVERNGQRGFVPGSYLEKL 416


>gi|155723000 mixed lineage kinase 4 [Homo sapiens]
          Length = 1036

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 11/83 (13%)

Query: 10  ALYVNVAESPDELSFRKGDIMTVLEQD--TQGLDGWWLCSLHGRQGIVPGNHLKILVGMY 67
           ALY   A   DELS R+G ++ VL QD    G +GWW   +  R GI P N++       
Sbjct: 45  ALYDYEARGEDELSLRRGQLVEVLSQDAAVSGDEGWWAGQVQRRLGIFPANYV------- 97

Query: 68  DKKPAGPGPGPPATPAQPQPGLH 90
              P  P   P   P++P   +H
Sbjct: 98  --APCRPAASPAPPPSRPSSPVH 118


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 24/50 (48%), Positives = 33/50 (66%)

Query: 10  ALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNH 59
           AL+   AE  DELSFR+G+ +TVL +D      WW  +LHG++G VP N+
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNY 814



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 45/163 (27%), Positives = 58/163 (35%), Gaps = 32/163 (19%)

Query: 71  PAGPGPGPPATPAQPQP---GLHAPVPPASQY------TPMLPNTYQPQ-PDSVYLVPTP 120
           P   GP  P T  +P+P   GL  PV  A          P+ P   QP  P     VP  
Sbjct: 448 PVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPEL 507

Query: 121 SKAQQGLYQVPGP----SPQFQSPPAKQTSTFSKQ---------------TPHHPFP--S 159
            +  + L ++P P        Q+P      T  KQ                P  P P  S
Sbjct: 508 EEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELS 567

Query: 160 PATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRS 202
           P T+  +   GP  PA     +PP A       + P SM+ RS
Sbjct: 568 PITEGSEARAGPPAPAPPA-PIPPPAPSQSSPPEQPQSMEMRS 609



 Score = 31.2 bits (69), Expect = 0.75
 Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 9/125 (7%)

Query: 70  KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG--- 126
           +P    P PP++P         P+P +  +   L N +     S  ++P      +    
Sbjct: 347 QPVSRIPMPPSSPQPRGAPRQRPIPLSMIFK--LQNAFWEHGASRAMLPGSPLFTRAPPP 404

Query: 127 -LYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLY---QVSPGPGGPAQDIYQVP 182
            L   P P PQ QS P  Q     +  P  P P+P         V+ GP  P  ++   P
Sbjct: 405 KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEP 464

Query: 183 PSAGM 187
              G+
Sbjct: 465 EIEGL 469


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 24/50 (48%), Positives = 33/50 (66%)

Query: 10  ALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNH 59
           AL+   AE  DELSFR+G+ +TVL +D      WW  +LHG++G VP N+
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNY 814



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 45/163 (27%), Positives = 58/163 (35%), Gaps = 32/163 (19%)

Query: 71  PAGPGPGPPATPAQPQP---GLHAPVPPASQY------TPMLPNTYQPQ-PDSVYLVPTP 120
           P   GP  P T  +P+P   GL  PV  A          P+ P   QP  P     VP  
Sbjct: 448 PVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPEL 507

Query: 121 SKAQQGLYQVPGP----SPQFQSPPAKQTSTFSKQ---------------TPHHPFP--S 159
            +  + L ++P P        Q+P      T  KQ                P  P P  S
Sbjct: 508 EEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELS 567

Query: 160 PATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRS 202
           P T+  +   GP  PA     +PP A       + P SM+ RS
Sbjct: 568 PITEGSEARAGPPAPAPPA-PIPPPAPSQSSPPEQPQSMEMRS 609



 Score = 31.2 bits (69), Expect = 0.75
 Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 9/125 (7%)

Query: 70  KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG--- 126
           +P    P PP++P         P+P +  +   L N +     S  ++P      +    
Sbjct: 347 QPVSRIPMPPSSPQPRGAPRQRPIPLSMIFK--LQNAFWEHGASRAMLPGSPLFTRAPPP 404

Query: 127 -LYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLY---QVSPGPGGPAQDIYQVP 182
            L   P P PQ QS P  Q     +  P  P P+P         V+ GP  P  ++   P
Sbjct: 405 KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEP 464

Query: 183 PSAGM 187
              G+
Sbjct: 465 EIEGL 469


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 42/142 (29%), Positives = 54/142 (38%), Gaps = 25/142 (17%)

Query: 68  DKKPAGPGPG-----PPATPAQPQPGLHAPVPPASQYTPMLPNTYQ----PQPDSVYLVP 118
           ++ P GPGPG     PP  P  P P      PP  Q  P  P  +Q    PQP      P
Sbjct: 43  NRGPMGPGPGQSGPKPPIPP--PPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPP 100

Query: 119 TP--SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHH---------PFPSPATDLYQV 167
            P    ++  + Q PGP+P   S P   +S      P           P P+P   +   
Sbjct: 101 PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSA 160

Query: 168 SPG---PGGPAQDIYQVPPSAG 186
            PG   P  P+  +   PP AG
Sbjct: 161 PPGAPPPTPPSSGVPTTPPQAG 182



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 38/130 (29%), Positives = 42/130 (32%), Gaps = 33/130 (25%)

Query: 71  PAGPGPGPPATP----AQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG 126
           P G GPGP  TP        PG   P PP+S      P    P P     VP P     G
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPA-AVPGPG---PG 197

Query: 127 LYQVPGP----------SPQFQSPPAKQTSTFSKQTP------------HHPFPSPATDL 164
             Q PGP           P+    P   T     + P            HHP   P    
Sbjct: 198 PKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP---PYHQQ 254

Query: 165 YQVSPGPGGP 174
           +   P PGGP
Sbjct: 255 HHQGPPPGGP 264


>gi|27544941 myosin IF [Homo sapiens]
          Length = 1098

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 21/53 (39%), Positives = 34/53 (64%), Gaps = 3/53 (5%)

Query: 9    KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLK 61
            +ALY  V +  DELSF   +++ +L +D  G   WW   LHG++G+ PGN+++
Sbjct: 1047 RALYQYVGQDVDELSFNVNEVIEILMEDPSG---WWKGRLHGQEGLFPGNYVE 1096


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,700,026
Number of Sequences: 37866
Number of extensions: 1039191
Number of successful extensions: 10311
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 359
Number of HSP's successfully gapped in prelim test: 974
Number of HSP's that attempted gapping in prelim test: 5537
Number of HSP's gapped (non-prelim): 3911
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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