Search of human proteins with 239750652

Search of human proteins with 239750652

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239750652 PREDICTED: hypothetical protein XP_002347499 [Homo
sapiens]
         (166 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239750652 PREDICTED: hypothetical protein XP_002347499 [Homo ...   331   2e-91
gi|239744960 PREDICTED: hypothetical protein XP_002343317 [Homo ...   331   2e-91
gi|239756120 PREDICTED: hypothetical protein [Homo sapiens]           305   1e-83
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         46   1e-05
gi|153070260 myristoylated alanine-rich protein kinase C substra...    45   4e-05
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    44   5e-05
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    44   5e-05
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    44   5e-05
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    44   5e-05
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    44   5e-05
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    44   5e-05
gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]            44   8e-05
gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]            44   8e-05
gi|169171345 PREDICTED: hypothetical protein [Homo sapiens]            43   1e-04
gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]            43   1e-04
gi|169172205 PREDICTED: hypothetical protein [Homo sapiens]            43   1e-04
gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo ...    43   1e-04
gi|169170949 PREDICTED: hypothetical protein [Homo sapiens]            43   1e-04
gi|45439359 triple functional domain (PTPRF interacting) [Homo s...    42   2e-04
gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]             42   2e-04
gi|33286446 opioid growth factor receptor [Homo sapiens]               40   7e-04
gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin prote...    40   7e-04
gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]             40   0.001
gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ...    40   0.001
gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo ...    40   0.001
gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo ...    40   0.001
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            40   0.001
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    40   0.001
gi|28269693 xylosyltransferase I [Homo sapiens]                        39   0.002
gi|7662162 ALEX2 protein [Homo sapiens]                                39   0.002

>gi|239750652 PREDICTED: hypothetical protein XP_002347499 [Homo
           sapiens]
          Length = 166

 Score =  331 bits (848), Expect = 2e-91
 Identities = 166/166 (100%), Positives = 166/166 (100%)

Query: 1   MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA 60
           MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA
Sbjct: 1   MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA 60

Query: 61  RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARG 120
           RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARG
Sbjct: 61  RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARG 120

Query: 121 RARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE 166
           RARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE
Sbjct: 121 RARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE 166


>gi|239744960 PREDICTED: hypothetical protein XP_002343317 [Homo
           sapiens]
          Length = 166

 Score =  331 bits (848), Expect = 2e-91
 Identities = 166/166 (100%), Positives = 166/166 (100%)

Query: 1   MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA 60
           MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA
Sbjct: 1   MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA 60

Query: 61  RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARG 120
           RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARG
Sbjct: 61  RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARG 120

Query: 121 RARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE 166
           RARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE
Sbjct: 121 RARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE 166


>gi|239756120 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 170

 Score =  305 bits (781), Expect = 1e-83
 Identities = 157/170 (92%), Positives = 157/170 (92%), Gaps = 4/170 (2%)

Query: 1   MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA 60
           MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA
Sbjct: 1   MEPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAA 60

Query: 61  RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGA----GAREAG 116
           RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGA          
Sbjct: 61  RLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAXXXXXXXXXX 120

Query: 117 AARGRARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE 166
             R RARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE
Sbjct: 121 PRRARARGPQPSPPGSSAAKARGRSWKRAAAVPKPTFSWLEFDGINFLSE 170


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 45/160 (28%), Positives = 63/160 (39%), Gaps = 22/160 (13%)

Query: 11  ADAAASAAIPAESAPPLQSHPENGVS------APGKGTAAKGARGGQSRCCSVVAARLLR 64
           A  AAS++   + APP  + P +          PG   ++   R  +SR  S    R  R
Sbjct: 529 AKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSR 588

Query: 65  LTPR--SSARRGRPESEPATNGTRQQGDLPALSAAAEAPREG--GKEEGAGAREAGAARG 120
            T R    +RR R   E      R     PA S+++ + RE   GK    G  +    R 
Sbjct: 589 STDRRRGGSRRSRSR-EKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRS 647

Query: 121 RARG-----------PQPSPPGSSAAKARGRSWKRAAAVP 149
           R+RG           P P+PP S +     R  +R  AVP
Sbjct: 648 RSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVP 687



 Score = 33.5 bits (75), Expect = 0.086
 Identities = 39/140 (27%), Positives = 51/140 (36%), Gaps = 18/140 (12%)

Query: 3   PRSAADAAADAAASAAIPAESAPP----LQSHPEN---GVSAPGKGTAAKGARGGQSRCC 55
           P  AA A   A      PA  AP     L  H E+   G      G  A       SR  
Sbjct: 419 PTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWG 478

Query: 56  SVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAP-REGGKEEGAGARE 114
            +   R +    R   R+  P   PA          PA +AAA  P R+  + E   + E
Sbjct: 479 GLDLRRKILTQRRERYRQRSPSPAPA----------PAPAAAAGPPTRKKSRRERKRSGE 528

Query: 115 AGAARGRARGPQPSPPGSSA 134
           A  A   + G QP+PP  ++
Sbjct: 529 AKEAASSSSGTQPAPPAPAS 548


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 48/153 (31%), Positives = 64/153 (41%), Gaps = 19/153 (12%)

Query: 2   EPRSAADAAADAAAS-------AAIPAESAPPLQSH-PENGVSA-PGKGTAAKGARGGQS 52
           EP +A   AA  +A+       AA P   A P++   P  G +A PG  TAA+G     +
Sbjct: 71  EPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAA 130

Query: 53  RCCSVVAAR------LLRLTPRSSARRGRPESEPATNG--TRQQGDLPALSAAAEAP-RE 103
              S   A           TP+   +R   +     +G   ++          AEAP  E
Sbjct: 131 SSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAE 190

Query: 104 GGKEEGAGAREAGAAR-GRARGPQPSPPGSSAA 135
           GGK+E AG   A AA  G A G Q + PG  AA
Sbjct: 191 GGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAA 223



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 43/142 (30%), Positives = 61/142 (42%), Gaps = 33/142 (23%)

Query: 8   DAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAA--KGARGGQSRCCSVVAARLLRL 65
           D AA  AA+AA  A +A   Q+      +APG+  AA  +GA GG  +            
Sbjct: 194 DEAAGGAAAAAAEAGAASGEQA------AAPGEEAAAGEEGAAGGDPQ----------EA 237

Query: 66  TPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRARGP 125
            P+ +A    PE  PA++ T+          AAE P    K E   A EAGA+      P
Sbjct: 238 KPQEAAVA--PEKPPASDETK----------AAEEP---SKVEEKKAEEAGASAAACEAP 282

Query: 126 QPSPPGSSAAKARGRSWKRAAA 147
             + PG+   +    + + AAA
Sbjct: 283 SAAGPGAPPEQEAAPAEEPAAA 304


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 36  SAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQ---QGDLP 92
           SAP KGT  KGA          VA         S  + G+PE +  ++       + + P
Sbjct: 227 SAPAKGTPGKGATPAPPGKAGAVA---------SQTKAGKPEEDSESSSEESSDSEEETP 277

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSA-AKARGRSWKR 144
           A  A  +A +  GK    GA  A A     +G  P+PPG +  A A+ ++ KR
Sbjct: 278 AAKALLQA-KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 329



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 12/114 (10%)

Query: 20  PAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESE 79
           PA++ P  ++      SAP K +  KGA     R     AA++         + G+ E +
Sbjct: 347 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV---------QVGKQEED 397

Query: 80  PATNGTRQQGDLPALSA--AAEAPREGGKEEGAGAREAGAARGRARGPQPSPPG 131
             ++      D  AL+A  AA+    G   +   A   G      +G  P PPG
Sbjct: 398 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG-PLGKGAGPVPPG 450


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 36  SAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQ---QGDLP 92
           SAP KGT  KGA          VA         S  + G+PE +  ++       + + P
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVA---------SQTKAGKPEEDSESSSEESSDSEEETP 354

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSA-AKARGRSWKR 144
           A  A  +A +  GK    GA  A A     +G  P+PPG +  A A+ ++ KR
Sbjct: 355 AAKALLQA-KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406



 Score = 35.4 bits (80), Expect = 0.023
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 16/122 (13%)

Query: 17  AAIPAESAPPLQSHPENGVSAPGK-GTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGR 75
           A + A S    +S       APGK G      +GG              L P   A++  
Sbjct: 221 AQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA-------------LPPAKRAKKPE 267

Query: 76  PESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAA 135
            ESE +  G+  + + PA + +     E   +  A +  A    G+  G  P+PPG + A
Sbjct: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGK--GATPAPPGKAGA 325

Query: 136 KA 137
            A
Sbjct: 326 VA 327



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 12/114 (10%)

Query: 20  PAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESE 79
           PA++ P  ++      SAP K +  KGA     R     AA++         + G+ E +
Sbjct: 424 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV---------QVGKQEED 474

Query: 80  PATNGTRQQGDLPALSA--AAEAPREGGKEEGAGAREAGAARGRARGPQPSPPG 131
             ++      D  AL+A  AA+    G   +   A   G      +G  P PPG
Sbjct: 475 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG-PLGKGAGPVPPG 527


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 36  SAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQ---QGDLP 92
           SAP KGT  KGA          VA         S  + G+PE +  ++       + + P
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVA---------SQTKAGKPEEDSESSSEESSDSEEETP 354

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSA-AKARGRSWKR 144
           A  A  +A +  GK    GA  A A     +G  P+PPG +  A A+ ++ KR
Sbjct: 355 AAKALLQA-KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406



 Score = 35.4 bits (80), Expect = 0.023
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 16/122 (13%)

Query: 17  AAIPAESAPPLQSHPENGVSAPGK-GTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGR 75
           A + A S    +S       APGK G      +GG              L P   A++  
Sbjct: 221 AQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA-------------LPPAKRAKKPE 267

Query: 76  PESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAA 135
            ESE +  G+  + + PA + +     E   +  A +  A    G+  G  P+PPG + A
Sbjct: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGK--GATPAPPGKAGA 325

Query: 136 KA 137
            A
Sbjct: 326 VA 327



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 12/114 (10%)

Query: 20  PAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESE 79
           PA++ P  ++      SAP K +  KGA     R     AA++         + G+ E +
Sbjct: 424 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV---------QVGKQEED 474

Query: 80  PATNGTRQQGDLPALSA--AAEAPREGGKEEGAGAREAGAARGRARGPQPSPPG 131
             ++      D  AL+A  AA+    G   +   A   G      +G  P PPG
Sbjct: 475 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG-PLGKGAGPVPPG 527


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 36  SAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQ---QGDLP 92
           SAP KGT  KGA          VA         S  + G+PE +  ++       + + P
Sbjct: 227 SAPAKGTPGKGATPAPPGKAGAVA---------SQTKAGKPEEDSESSSEESSDSEEETP 277

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSA-AKARGRSWKR 144
           A  A  +A +  GK    GA  A A     +G  P+PPG +  A A+ ++ KR
Sbjct: 278 AAKALLQA-KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 329



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 12/114 (10%)

Query: 20  PAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESE 79
           PA++ P  ++      SAP K +  KGA     R     AA++         + G+ E +
Sbjct: 347 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV---------QVGKQEED 397

Query: 80  PATNGTRQQGDLPALSA--AAEAPREGGKEEGAGAREAGAARGRARGPQPSPPG 131
             ++      D  AL+A  AA+    G   +   A   G      +G  P PPG
Sbjct: 398 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG-PLGKGAGPVPPG 450


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 36  SAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQ---QGDLP 92
           SAP KGT  KGA          VA         S  + G+PE +  ++       + + P
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVA---------SQTKAGKPEEDSESSSEESSDSEEETP 354

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSA-AKARGRSWKR 144
           A  A  +A +  GK    GA  A A     +G  P+PPG +  A A+ ++ KR
Sbjct: 355 AAKALLQA-KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406



 Score = 35.4 bits (80), Expect = 0.023
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 16/122 (13%)

Query: 17  AAIPAESAPPLQSHPENGVSAPGK-GTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGR 75
           A + A S    +S       APGK G      +GG              L P   A++  
Sbjct: 221 AQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA-------------LPPAKRAKKPE 267

Query: 76  PESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAA 135
            ESE +  G+  + + PA + +     E   +  A +  A    G+  G  P+PPG + A
Sbjct: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGK--GATPAPPGKAGA 325

Query: 136 KA 137
            A
Sbjct: 326 VA 327



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 12/114 (10%)

Query: 20  PAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESE 79
           PA++ P  ++      SAP K +  KGA     R     AA++         + G+ E +
Sbjct: 424 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV---------QVGKQEED 474

Query: 80  PATNGTRQQGDLPALSA--AAEAPREGGKEEGAGAREAGAARGRARGPQPSPPG 131
             ++      D  AL+A  AA+    G   +   A   G      +G  P PPG
Sbjct: 475 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG-PLGKGAGPVPPG 527


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 36  SAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQ---QGDLP 92
           SAP KGT  KGA          VA         S  + G+PE +  ++       + + P
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVA---------SQTKAGKPEEDSESSSEESSDSEEETP 354

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSA-AKARGRSWKR 144
           A  A  +A +  GK    GA  A A     +G  P+PPG +  A A+ ++ KR
Sbjct: 355 AAKALLQA-KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406



 Score = 35.4 bits (80), Expect = 0.023
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 16/122 (13%)

Query: 17  AAIPAESAPPLQSHPENGVSAPGK-GTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGR 75
           A + A S    +S       APGK G      +GG              L P   A++  
Sbjct: 221 AQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA-------------LPPAKRAKKPE 267

Query: 76  PESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAA 135
            ESE +  G+  + + PA + +     E   +  A +  A    G+  G  P+PPG + A
Sbjct: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGK--GATPAPPGKAGA 325

Query: 136 KA 137
            A
Sbjct: 326 VA 327



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 12/114 (10%)

Query: 20  PAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESE 79
           PA++ P  ++      SAP K +  KGA     R     AA++         + G+ E +
Sbjct: 424 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV---------QVGKQEED 474

Query: 80  PATNGTRQQGDLPALSA--AAEAPREGGKEEGAGAREAGAARGRARGPQPSPPG 131
             ++      D  AL+A  AA+    G   +   A   G      +G  P PPG
Sbjct: 475 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG-PLGKGAGPVPPG 527


>gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 43.5 bits (101), Expect = 8e-05
 Identities = 42/149 (28%), Positives = 56/149 (37%), Gaps = 14/149 (9%)

Query: 2   EPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAAR 61
           +P  A    A A + AA  A S PPLQ  P  G ++P +   A    G ++   S    R
Sbjct: 256 QPPLARLLLASAVSLAASLARSPPPLQ--PRLGSASPPR--LAAPLAGSRAPSLSPFPRR 311

Query: 62  LLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGR 121
             R   RS A  G P     + G    G            R GG+E     R  G A G 
Sbjct: 312 CRRRAERSPAGHGLPLPRSLSRGGEVVG---------ARRRRGGEERRVRGRRQGCALGS 362

Query: 122 ARGPQ-PSPPGSSAAKARGRSWKRAAAVP 149
              P  P+ PG +  +   R W++    P
Sbjct: 363 PPIPAGPAAPGRAGERRAARQWRKRGGGP 391



 Score = 34.7 bits (78), Expect = 0.038
 Identities = 41/142 (28%), Positives = 57/142 (40%), Gaps = 24/142 (16%)

Query: 3   PRSAADAAADAAASAA-IP------AESAPPLQSHP-ENGVSAPGKGTAAKGARGGQSRC 54
           PR AA  A   A S +  P      AE +P     P    +S  G+   A+  RGG+ R 
Sbjct: 291 PRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERR 350

Query: 55  -------CSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKE 107
                  C++ +  +    P   A  GR     A    R++G  P +S     PREG + 
Sbjct: 351 VRGRRQGCALGSPPI----PAGPAAPGRAGERRAARQWRKRGGGPGVS-----PREGAQG 401

Query: 108 EGAGAREAGAARGRARGPQPSP 129
           EG        ARG +   +PSP
Sbjct: 402 EGVRGGVTPRARGSSTCLRPSP 423


>gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 43.5 bits (101), Expect = 8e-05
 Identities = 42/149 (28%), Positives = 56/149 (37%), Gaps = 14/149 (9%)

Query: 2   EPRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAAR 61
           +P  A    A A + AA  A S PPLQ  P  G ++P +   A    G ++   S    R
Sbjct: 256 QPPLARLLLASAVSLAASLARSPPPLQ--PRLGSASPPR--LAAPLAGSRAPSLSPFPRR 311

Query: 62  LLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGR 121
             R   RS A  G P     + G    G            R GG+E     R  G A G 
Sbjct: 312 CRRRAERSPAGHGLPLPRSLSRGGEVVG---------ARRRRGGEERRVRGRRQGCALGS 362

Query: 122 ARGPQ-PSPPGSSAAKARGRSWKRAAAVP 149
              P  P+ PG +  +   R W++    P
Sbjct: 363 PPIPAGPAAPGRAGERRAARQWRKRGGGP 391



 Score = 34.7 bits (78), Expect = 0.038
 Identities = 41/142 (28%), Positives = 57/142 (40%), Gaps = 24/142 (16%)

Query: 3   PRSAADAAADAAASAA-IP------AESAPPLQSHP-ENGVSAPGKGTAAKGARGGQSRC 54
           PR AA  A   A S +  P      AE +P     P    +S  G+   A+  RGG+ R 
Sbjct: 291 PRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERR 350

Query: 55  -------CSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKE 107
                  C++ +  +    P   A  GR     A    R++G  P +S     PREG + 
Sbjct: 351 VRGRRQGCALGSPPI----PAGPAAPGRAGERRAARQWRKRGGGPGVS-----PREGAQG 401

Query: 108 EGAGAREAGAARGRARGPQPSP 129
           EG        ARG +   +PSP
Sbjct: 402 EGVRGGVTPRARGSSTCLRPSP 423


>gi|169171345 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 15/102 (14%)

Query: 58  VAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGA 117
           +A RL ++ P ++  RGR    P   G R  G LPA  +   A R G   + AGAR  G 
Sbjct: 106 LAGRLQQVRPGAAGPRGRL---PWVTGPRPAGSLPAAQSPPPAERPG--RDAAGARVCGT 160

Query: 118 ARG----RARGPQP------SPPGSSAAKARGRSWKRAAAVP 149
            RG     A  PQP      S   ++A+   G++ K+A  +P
Sbjct: 161 QRGGCARAAEAPQPTGGRGCSRGSATASGVGGKAIKKAQRIP 202


>gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 255

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 42/134 (31%), Positives = 54/134 (40%), Gaps = 24/134 (17%)

Query: 15  ASAAIPAESAPPLQSHP---ENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSA 71
           +++A+PA    P ++ P     GV  PG G + + ARGG +            L  R +A
Sbjct: 137 SASALPAPRLCPQRASPGCSSPGVRGPGGGASPR-ARGGNAAAA---------LAARQAA 186

Query: 72  RRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAAR-GRARGPQPSPP 130
             GR  S              A  A A+ PR   +  GAGAR     R G    P P P 
Sbjct: 187 GGGRSRSAFVAGRD-------AALACAQLPR---RPRGAGARRGMRRRLGAGERPAPRPR 236

Query: 131 GSSAAKARGRSWKR 144
           G   A ARG  W R
Sbjct: 237 GPPRAPARGARWLR 250


>gi|169172205 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 15/102 (14%)

Query: 58  VAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGA 117
           +A RL ++ P ++  RGR    P   G R  G LPA  +   A R G   + AGAR  G 
Sbjct: 106 LAGRLQQVRPGAAGPRGRL---PWVTGPRPAGSLPAAQSPPPAERPG--RDAAGARVCGT 160

Query: 118 ARG----RARGPQP------SPPGSSAAKARGRSWKRAAAVP 149
            RG     A  PQP      S   ++A+   G++ K+A  +P
Sbjct: 161 QRGGCARAAEAPQPTGGRGCSRGSATASGVGGKAIKKAQRIP 202


>gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo
           sapiens]
          Length = 255

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 42/134 (31%), Positives = 54/134 (40%), Gaps = 24/134 (17%)

Query: 15  ASAAIPAESAPPLQSHP---ENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSA 71
           +++A+PA    P ++ P     GV  PG G + + ARGG +            L  R +A
Sbjct: 137 SASALPAPRLCPQRASPGCSSPGVRGPGGGASPR-ARGGNAAAA---------LAARQAA 186

Query: 72  RRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAAR-GRARGPQPSPP 130
             GR  S              A  A A+ PR   +  GAGAR     R G    P P P 
Sbjct: 187 GGGRSRSAFVAGRD-------AALACAQLPR---RPRGAGARRGMRRRLGAGERPAPRPR 236

Query: 131 GSSAAKARGRSWKR 144
           G   A ARG  W R
Sbjct: 237 GPPRAPARGARWLR 250


>gi|169170949 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 15/102 (14%)

Query: 58  VAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGA 117
           +A RL ++ P ++  RGR    P   G R  G LPA  +   A R G   + AGAR  G 
Sbjct: 106 LAGRLQQVRPGAAGPRGRL---PWVTGPRPAGSLPAAQSPPPAERPG--RDAAGARVCGT 160

Query: 118 ARG----RARGPQP------SPPGSSAAKARGRSWKRAAAVP 149
            RG     A  PQP      S   ++A+   G++ K+A  +P
Sbjct: 161 QRGGCARAAEAPQPTGGRGCSRGSATASGVGGKAIKKAQRIP 202


>gi|45439359 triple functional domain (PTPRF interacting) [Homo
            sapiens]
          Length = 3097

 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 39/150 (26%), Positives = 54/150 (36%), Gaps = 18/150 (12%)

Query: 5    SAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLR 64
            +++ A AD  +  + P  S PP  + PE G SAP +      A G +     +   ++L 
Sbjct: 2357 ASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLE 2416

Query: 65   LTPRSSARR--GRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRA 122
             +PR  A    G     PA +     G LP            GK     A    +    A
Sbjct: 2417 -SPRKGAANASGSSPDAPAKDARASLGTLPL-----------GKPRAGAASPLNSPLSSA 2464

Query: 123  ---RGPQPSPPGSSAAKARGRSWKRAAAVP 149
                G +P PP S   K  G  W    A P
Sbjct: 2465 VPSLGKEPFPPSSPLQKG-GSFWSSIPASP 2493


>gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]
          Length = 496

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 36/107 (33%), Positives = 39/107 (36%), Gaps = 6/107 (5%)

Query: 31  PENGVSAPGKGTAAKGARGGQSRC-CSVVAARLLRLTPRSSARRGRPESEPATNGTRQQG 89
           PE G  AP    AA+ +     +C C    A    L     A  G     PAT G    G
Sbjct: 310 PEGGGEAPAPAAAAEPSEDTLYQCDCGTFFASAAALASHLEAHSG-----PATYGCGHCG 364

Query: 90  DLPALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAAK 136
            L A  AA E  R     EG G   A AAR R       P GS   K
Sbjct: 365 ALYAALAALEEHRRVSHGEGGGEEAATAAREREPASGEPPSGSGRGK 411


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 44/150 (29%), Positives = 53/150 (35%), Gaps = 18/150 (12%)

Query: 5   SAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAA--KGARGGQSRCCSVVAARL 62
           + A   A   A A  PA S  P   H ENGV    +G     +G  G  S          
Sbjct: 470 AVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSE--------- 520

Query: 63  LRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGR- 121
              TP  S   G    EPA + +   G  PA   A + P E    E  G R AG A    
Sbjct: 521 ---TPGPSP-AGPAGDEPAESPSETPGPRPA-GPAGDEPAE-SPSETPGPRPAGPAGDEP 574

Query: 122 ARGPQPSPPGSSAAKARGRSWKRAAAVPKP 151
           A  P  +P  S A   R    +  +  P P
Sbjct: 575 AESPSETPGPSPAGPTRDEPAESPSETPGP 604



 Score = 28.5 bits (62), Expect = 2.8
 Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 7/126 (5%)

Query: 6   AADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRL 65
           A D  A++ +    P  + P      E+    PG   A  G  G +    +   +     
Sbjct: 530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA--GPAGDEP---AESPSETPGP 584

Query: 66  TPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRARGP 125
           +P    R    ES   T G R  G  PA    AE+P E      AG      A   +  P
Sbjct: 585 SPAGPTRDEPAESPSETPGPRPAG--PAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 642

Query: 126 QPSPPG 131
            PSP G
Sbjct: 643 GPSPAG 648


>gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin protein
           ligase 2 [Homo sapiens]
          Length = 1572

 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 16/137 (11%)

Query: 5   SAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLR 64
           S+ D    +  SA  P    P   S  E   +   + T++  A G Q   C+  +  +++
Sbjct: 654 SSVDTRCSSLESARFP--ETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQ 711

Query: 65  LTPRSSARRGR-----PESEPATNGTRQQGDLPALSAAAEAP--REG------GKEEGAG 111
           +        G      P+ E      +++G L   +AAAE+P   EG      G  EGA 
Sbjct: 712 VPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGTCEGAT 771

Query: 112 AREAGAARG-RARGPQP 127
           A+E GA  G +A G QP
Sbjct: 772 AQEEGATGGSQANGHQP 788


>gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]
          Length = 340

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 41/142 (28%), Positives = 55/142 (38%), Gaps = 26/142 (18%)

Query: 3   PRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARL 62
           P      ++DAA      A   P   +  E   + PG   AA    G     C+V +A L
Sbjct: 39  PAPPGGGSSDAAGKPPAGALGTPAAAAANELNNNLPGGAPAAPAVPGPGGVNCAVGSAML 98

Query: 63  LRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRA 122
            R  P       R E EP           PA SA+A  P +  +EE  G  E    +G++
Sbjct: 99  TRAAPGPR----RSEDEP-----------PAASASAAPPPQRDEEEPDGVPE----KGKS 139

Query: 123 RGPQPSPPGSSAAKARGRSWKR 144
            GP       SA K +G+  KR
Sbjct: 140 SGP-------SARKGKGQIEKR 154


>gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo
           sapiens]
          Length = 355

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 12/124 (9%)

Query: 13  AAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSAR 72
           A +S+ +P    P  +     G+    +  AA+   GG+S       AR    T R   R
Sbjct: 143 AHSSSRVPRPRLPSQRRGASCGLGPGPESRAARQGLGGRS-----ARAR----TRRGPHR 193

Query: 73  RGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAG---AARGRARGPQPSP 129
             RPE  P   G RQ G LP       A   G    G      G   AA   AR    SP
Sbjct: 194 TRRPEPGPHHTGARQAGPLPGTRGRTRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSP 253

Query: 130 PGSS 133
           PG S
Sbjct: 254 PGRS 257



 Score = 35.0 bits (79), Expect = 0.029
 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 8/106 (7%)

Query: 37  APGKGTAAKGA----RGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLP 92
           A G G+AA+G     RGG     +  AAR L L+P   +R   P S  A    R     P
Sbjct: 221 AAGTGSAARGPARHLRGGS--VAAAAAARCLGLSPPGRSRLFSPRSSLARPPLRFPPARP 278

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAAKAR 138
           ALS +A   R         +R A     RA    PS P +S  +AR
Sbjct: 279 ALSPSAR--RRCRVNWNQSSRPASHNAQRAARHIPSRPRASGLRAR 322


>gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo
           sapiens]
          Length = 355

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 12/124 (9%)

Query: 13  AAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSAR 72
           A +S+ +P    P  +     G+    +  AA+   GG+S       AR    T R   R
Sbjct: 143 AHSSSRVPRPRLPSQRRGASCGLGPGPESRAARQGLGGRS-----ARAR----TRRGPHR 193

Query: 73  RGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAG---AARGRARGPQPSP 129
             RPE  P   G RQ G LP       A   G    G      G   AA   AR    SP
Sbjct: 194 TRRPEPGPHHTGARQAGPLPGTRGRTRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSP 253

Query: 130 PGSS 133
           PG S
Sbjct: 254 PGRS 257



 Score = 35.0 bits (79), Expect = 0.029
 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 8/106 (7%)

Query: 37  APGKGTAAKGA----RGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLP 92
           A G G+AA+G     RGG     +  AAR L L+P   +R   P S  A    R     P
Sbjct: 221 AAGTGSAARGPARHLRGGS--VAAAAAARCLGLSPPGRSRLFSPRSSLARPPLRFPPARP 278

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAAKAR 138
           ALS +A   R         +R A     RA    PS P +S  +AR
Sbjct: 279 ALSPSAR--RRCRVNWNQSSRPASHNAQRAARHIPSRPRASGLRAR 322


>gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo
           sapiens]
          Length = 355

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 12/124 (9%)

Query: 13  AAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSAR 72
           A +S+ +P    P  +     G+    +  AA+   GG+S       AR    T R   R
Sbjct: 143 AHSSSRVPRPRLPSQRRGASCGLGPGPESRAARQGLGGRS-----ARAR----TRRGPHR 193

Query: 73  RGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAG---AARGRARGPQPSP 129
             RPE  P   G RQ G LP       A   G    G      G   AA   AR    SP
Sbjct: 194 TRRPEPGPHHTGARQAGPLPGTRGRTRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSP 253

Query: 130 PGSS 133
           PG S
Sbjct: 254 PGRS 257



 Score = 35.0 bits (79), Expect = 0.029
 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 8/106 (7%)

Query: 37  APGKGTAAKGA----RGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLP 92
           A G G+AA+G     RGG     +  AAR L L+P   +R   P S  A    R     P
Sbjct: 221 AAGTGSAARGPARHLRGGS--VAAAAAARCLGLSPPGRSRLFSPRSSLARPPLRFPPARP 278

Query: 93  ALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAAKAR 138
           ALS +A   R         +R A     RA    PS P +S  +AR
Sbjct: 279 ALSPSAR--RRCRVNWNQSSRPASHNAQRAARHIPSRPRASGLRAR 322


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 39.7 bits (91), Expect = 0.001
 Identities = 48/166 (28%), Positives = 64/166 (38%), Gaps = 31/166 (18%)

Query: 10  AADAAASAAIPAESAPPLQSHPENGVSAPGKGTAA----KGARGGQSRCC----SVVAAR 61
           AA A     + AESA P  S    GV   G G       K A GG+          VA +
Sbjct: 24  AALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQKGAVAGK 83

Query: 62  LLRLTPRSSA------RRGRPESEPATNGTRQQGDL---------PALSAAAEAPR---- 102
             R   + +A       RG  E + A  GT+  G            A +  ++ PR    
Sbjct: 84  EARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQ 143

Query: 103 ----EGGKEEGAGAREAGAARGRARGPQPSPPGSSAAKARGRSWKR 144
                G K  GAGA++A AA G        P  ++AA A+ RS K+
Sbjct: 144 KSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKK 189



 Score = 31.6 bits (70), Expect = 0.33
 Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 16/154 (10%)

Query: 3   PRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGK---GTAAKGARGGQSRCCSVVA 59
           P+ AA  A         P +     Q     G S  GK   G   K  R GQ+   +   
Sbjct: 228 PKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAK 287

Query: 60  ARLLRLTPRSSARRGRPESEPATNG------------TRQQGDLPALSAAAEAPREGG-K 106
            R         A +GR    P + G             R++G     +AAA   R GG +
Sbjct: 288 RRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQ 347

Query: 107 EEGAGAREAGAARGRARGPQPSPPGSSAAKARGR 140
           ++ A        + R RG +P    +SAA A+ R
Sbjct: 348 QKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSR 381



 Score = 30.8 bits (68), Expect = 0.56
 Identities = 27/115 (23%), Positives = 44/115 (38%), Gaps = 17/115 (14%)

Query: 41  GTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAA-- 98
           G  ++G+ G Q R     AA        +  +      +P     + +GD    +A    
Sbjct: 650 GATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGIN 709

Query: 99  ------EAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAAKARGRSWKRAAA 147
                 + PR G    G GA+  G+   ++RG         +  A+ RS K+AAA
Sbjct: 710 PWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRG---------SGGAKSRSGKKAAA 755



 Score = 28.9 bits (63), Expect = 2.1
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 11/108 (10%)

Query: 37  APGKGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSA 96
           A   GT + G RG + R     AA      PR  A++       A  G++ +G     +A
Sbjct: 108 AAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKS------AAAGSKNRGAGAQKAA 161

Query: 97  AAEAPREGGKEEGAGAREAGAARGRARGPQPSPPGSSAAKARGRSWKR 144
           AA   +  G E+   A  AGA     + P+        AK+RG   K+
Sbjct: 162 AAAGVKSQGGEKPQKAAAAGAKSRSGKKPR-----RRGAKSRGDEDKK 204



 Score = 27.3 bits (59), Expect = 6.1
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 7/58 (12%)

Query: 92  PALSAAAEAPR---EGGKEEGAGAREAGAARGRARGPQPSPPGSSAAKARGRSWKRAA 146
           PALSAAA   +    G K+       AG  + R RG +    G+ A K   + W++AA
Sbjct: 40  PALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQK----GAVAGKEARQHWQKAA 93



 Score = 27.3 bits (59), Expect = 6.1
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 9/85 (10%)

Query: 40  KGTAAKGARGGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAE 99
           K  AAK  RGG S+       +  R  P+++  RG           R++G   A   AAE
Sbjct: 413 KAPAAK-PRGGGSK-------KPRRRGPKAAKSRGGKSRSGGGKKPRRRGQ-KARQKAAE 463

Query: 100 APREGGKEEGAGAREAGAARGRARG 124
           A  E   ++  G ++A AA  ++RG
Sbjct: 464 AGAESRGDKKQGRQKASAAGTKSRG 488


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 39.7 bits (91), Expect = 0.001
 Identities = 39/131 (29%), Positives = 45/131 (34%), Gaps = 8/131 (6%)

Query: 10  AADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARLLRLTPRS 69
           A  A A  A PAE AP     P      P  G A  G  G Q          L+   P  
Sbjct: 68  AGAAGAGPAAPAEGAPGAAPEP------PPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121

Query: 70  SARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRARGPQPSP 129
            A + RP  E +           A++A  E P   G  + AG     A  G   GP P P
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPE-PAPAGPAKPAGPAALAARAGPGPGPGPGP 180

Query: 130 -PGSSAAKARG 139
            PG    K  G
Sbjct: 181 GPGPGPGKPAG 191



 Score = 33.5 bits (75), Expect = 0.086
 Identities = 45/159 (28%), Positives = 58/159 (36%), Gaps = 25/159 (15%)

Query: 3   PRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARL 62
           P + A  +  AA + A PA + PP    P      PG       A               
Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA------------ 296

Query: 63  LRLTPRSSARRG-----RPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGA 117
             + P ++A+ G      P   PA  G       P   AAA AP  G K E +  R   A
Sbjct: 297 --VPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAE-SPKRVVQA 353

Query: 118 ARGRARGPQPSPPGSSAAK-ARGRSWKRA----AAVPKP 151
           A   A+    S P S+AA    G + + A    AAVP P
Sbjct: 354 APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP 392


>gi|28269693 xylosyltransferase I [Homo sapiens]
          Length = 959

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 74  GRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAG----AREAGAARGRARGPQPSP 129
           G  +  PA    R++ DLPA  AAA     GG   G G    AR  G   G  RG QP+ 
Sbjct: 53  GGEQPPPAPAPRRERRDLPAEPAAARGGGGGGGGGGGGRGPQARARGGGPGEPRGQQPAS 112

Query: 130 PGSSAAKA 137
            G+  A+A
Sbjct: 113 RGALPARA 120


>gi|7662162 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 36/136 (26%), Positives = 51/136 (37%), Gaps = 12/136 (8%)

Query: 3   PRSAADAAADAAASAAIPAESAPPLQSHPENGVSAPGKGTAAKGARGGQSRCCSVVAARL 62
           PR A  + A       +P E+A P +     GV+AP K   A G         + V A  
Sbjct: 167 PREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPA-- 224

Query: 63  LRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEEGAGAREAGAARGRA 122
              TP  +A        P T+G+ +   +P  SAA +A    G   GA  +   A     
Sbjct: 225 ---TPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKA--TPGAHTGAIPKATSAT---- 275

Query: 123 RGPQPSPPGSSAAKAR 138
            G  P   G    ++R
Sbjct: 276 -GAVPKGGGKGVTRSR 290


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,871,869
Number of Sequences: 37866
Number of extensions: 440074
Number of successful extensions: 5441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 745
Number of HSP's that attempted gapping in prelim test: 4232
Number of HSP's gapped (non-prelim): 1766
length of query: 166
length of database: 18,247,518
effective HSP length: 95
effective length of query: 71
effective length of database: 14,650,248
effective search space: 1040167608
effective search space used: 1040167608
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.