Search of human proteins with 10863937

Search of human proteins with 10863937

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10863937 tumor necrosis factor, alpha-induced protein 1
[Homo sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...   641   0.0  
gi|13994353 potassium channel tetramerisation domain containing ...   441   e-124
gi|30578412 potassium channel tetramerisation domain containing ...   416   e-116
gi|71143104 potassium channel tetramerisation domain containing ...    78   9e-15
gi|189571693 potassium channel tetramerisation domain containing...    72   6e-13
gi|189571691 potassium channel tetramerisation domain containing...    72   6e-13
gi|23308551 potassium channel tetramerisation domain containing ...    69   4e-12
gi|45387953 potassium channel tetramerization domain containing ...    62   5e-10
gi|146198864 potassium channel tetramerisation domain containing...    62   9e-10
gi|169234778 potassium channel tetramerisation domain containing...    60   2e-09
gi|53829365 potassium channel tetramerisation domain containing ...    60   2e-09
gi|9506651 potassium channel tetramerisation domain containing 5...    60   3e-09
gi|142356950 potassium channel tetramerisation domain containing...    55   8e-08
gi|194018443 potassium channel tetramerisation domain containing...    55   1e-07
gi|194018441 potassium channel tetramerisation domain containing...    55   1e-07
gi|194018439 potassium channel tetramerisation domain containing...    55   1e-07
gi|38198663 potassium channel tetramerisation domain containing ...    54   1e-07
gi|55926200 potassium channel tetramerisation domain containing ...    54   2e-07
gi|218505694 potassium channel tetramerisation domain containing...    52   5e-07
gi|209969708 potassium channel tetramerisation domain containing...    52   5e-07
gi|40217617 potassium channel tetramerisation domain containing ...    52   5e-07
gi|19923973 potassium channel tetramerisation domain containing ...    52   9e-07
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  50   2e-06
gi|46255026 potassium channel tetramerisation domain containing ...    50   3e-06
gi|39753959 potassium channel tetramerisation domain containing ...    47   2e-05
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       47   2e-05
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       47   2e-05
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    45   6e-05
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    45   6e-05
gi|169180181 PREDICTED: similar to potassium channel tetramerisa...    45   6e-05

>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score =  641 bits (1654), Expect = 0.0
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGR 60
           MSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGR
Sbjct: 1   MSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGR 60

Query: 61  MEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMC 120
           MEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMC
Sbjct: 61  MEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMC 120

Query: 121 QSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLL 180
           QSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLL
Sbjct: 121 QSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLL 180

Query: 181 KNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVE 240
           KNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVE
Sbjct: 181 KNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVE 240

Query: 241 FPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEETFELRDRVRRIHVKRY 300
           FPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEETFELRDRVRRIHVKRY
Sbjct: 241 FPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEETFELRDRVRRIHVKRY 300

Query: 301 STYDDRQLGHQSTHRD 316
           STYDDRQLGHQSTHRD
Sbjct: 301 STYDDRQLGHQSTHRD 316


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score =  441 bits (1135), Expect = e-124
 Identities = 222/314 (70%), Positives = 262/314 (83%), Gaps = 7/314 (2%)

Query: 1   MSGDTCLCPA-SGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSG 59
           MSG++ +  A   A  + + FKG    +KYV+LNVGG+LYYTT++ LT+ DTMLKAMFSG
Sbjct: 4   MSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSG 63

Query: 60  RMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNM 119
           RMEVLTD EGWILIDRCGKHFGTILNYLRD  + LP++R+EI+EL+AEAKYYL+QGLV  
Sbjct: 64  RMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEE 123

Query: 120 CQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHL 179
           CQ+ALQ+K D+Y+P C +P+ITS KEE++LI +S KP VKLLYNRSNNKYSYTSNSDD++
Sbjct: 124 CQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNM 182

Query: 180 LKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKV 239
           LKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRK+AEVCCTSIVYATEKKQTKV
Sbjct: 183 LKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKV 242

Query: 240 EFPEARIYEETLNVLLYETP--RVPDNSLLEATSRSRSQASPSEDEETFELRDRVRRIHV 297
           EFPEARIYEETLN+LLYE    R PDN+LLEAT  +  ++   +++E  E  +RVRRIH+
Sbjct: 243 EFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRIHI 302

Query: 298 KRYSTYDDRQLGHQ 311
           KR    DDR   HQ
Sbjct: 303 KR---PDDRAHLHQ 313


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score =  416 bits (1070), Expect = e-116
 Identities = 203/322 (63%), Positives = 252/322 (78%), Gaps = 14/322 (4%)

Query: 9   PASGAKPKLSGFKGGGL--------------GNKYVQLNVGGSLYYTTVRALTRHDTMLK 54
           PA+ A P L   K  GL               +KYV+LNVGGSL+YTT+R LT  DTMLK
Sbjct: 8   PAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQDTMLK 67

Query: 55  AMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQ 114
           AMFSGR+EVLTD  GW+LIDR G+HFGTILNYLRD ++ LP++ +E+ EL+ EA+YYL+Q
Sbjct: 68  AMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQ 127

Query: 115 GLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSN 174
           GL+  CQ ALQ K+++  P+C IP++TS +EE++L+ S++KPVVKLL+NRSNNKYSYTS 
Sbjct: 128 GLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKYSYTST 187

Query: 175 SDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEK 234
           SDD+LLKNIELFDKL+LRF+GR+LF+KDV+GDEICCWSFYGQGRK+AEVCCTSIVYATEK
Sbjct: 188 SDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSIVYATEK 247

Query: 235 KQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEETFELRDRVRR 294
           KQTKVEFPEARI+EETLN+L+YETPR PD +LLEAT  +         E+      RVRR
Sbjct: 248 KQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEENREHRVRR 307

Query: 295 IHVKRYSTYDDRQLGHQSTHRD 316
           IHV+R+ T+D+R  G Q   +D
Sbjct: 308 IHVRRHITHDERPHGQQIVFKD 329


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 78.2 bits (191), Expect = 9e-15
 Identities = 59/172 (34%), Positives = 90/172 (52%), Gaps = 14/172 (8%)

Query: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           + LNVGG LY T++  LT   D+ML AMFSG+M    D +G   IDR GK F  ILN+LR
Sbjct: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64

Query: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKK-DSYQPVCNIPIITSLKEEE 147
              + LP++ QE+  L  EA +Y +Q L+     ALQ+K+ +  +   N  +  +L +  
Sbjct: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLI----EALQEKEVELSKAEKNAMLNITLNQRV 120

Query: 148 RLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLF 199
           + +  + +   ++        YS +S+S +    NI     L L+  G  LF
Sbjct: 121 QTVHFTVREAPQI--------YSLSSSSMEVFNANIFSTSCLFLKLLGSKLF 164


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 49/130 (37%), Positives = 66/130 (50%), Gaps = 6/130 (4%)

Query: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           V LNVGG LY T++  LTR+ D+ML AMF G      D +G   IDR G  F  +LN+LR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEER 148
              +TLP + +E   L  EA +Y I+ L+      L D K  Y P+     +  L    +
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLI----QCLNDPKPLY-PMDTFEEVVELSSTRK 128

Query: 149 LIESSTKPVV 158
           L + S    V
Sbjct: 129 LSKYSNPVAV 138


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 49/130 (37%), Positives = 66/130 (50%), Gaps = 6/130 (4%)

Query: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           V LNVGG LY T++  LTR+ D+ML AMF G      D +G   IDR G  F  +LN+LR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEER 148
              +TLP + +E   L  EA +Y I+ L+      L D K  Y P+     +  L    +
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLI----QCLNDPKPLY-PMDTFEEVVELSSTRK 128

Query: 149 LIESSTKPVV 158
           L + S    V
Sbjct: 129 LSKYSNPVAV 138


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 39/94 (41%), Positives = 56/94 (59%), Gaps = 4/94 (4%)

Query: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           V LN+GG+ + T +  L  + DTML AMFSGR  + TD EG   IDR G HFG +LN+LR
Sbjct: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112

Query: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQS 122
              +     R+ ++ +  EA+YY I  L+   ++
Sbjct: 113 SGDL---PPRERVRAVYKEAQYYAIGPLLEQLEN 143


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 46/130 (35%), Positives = 66/130 (50%), Gaps = 20/130 (15%)

Query: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           ++LNVGG +Y     +L R  D+ML +MFSGR  + TD+ G  +IDR G+ F  +L+YL 
Sbjct: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYLH 73

Query: 89  DDTITLPQNRQEIKELMAEAKYY-------LIQGLVNMCQS-----------ALQDKKDS 130
            + + +P + Q    L  EA Y+       L   L N  ++           AL D  DS
Sbjct: 74  GE-VQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDS 132

Query: 131 YQPVCNIPII 140
           Y  VCN P +
Sbjct: 133 YGLVCNKPTV 142


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 35/103 (33%), Positives = 60/103 (58%), Gaps = 1/103 (0%)

Query: 21  KGGGLGNKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKH 79
           +G    +  + LNVGG LY T  + LT++ DT L+ + +G++    D +G   IDR G  
Sbjct: 26  QGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLL 85

Query: 80  FGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQS 122
           F  +LN+LR+  + LP+  +E + L  EA+++ ++GL    +S
Sbjct: 86  FRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKS 128


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 37/117 (31%), Positives = 66/117 (56%), Gaps = 3/117 (2%)

Query: 13  AKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGRMEVLTDKE--GW 70
           A P  +G +  G   K+V+LNVGG+++ TT + L R      +      E+ +D++  G 
Sbjct: 16  APPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGA 75

Query: 71  ILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDK 127
            LIDR   +FG ILN+LR   + L ++  E + ++ EA++Y I  L+ + +  +++K
Sbjct: 76  YLIDRDPTYFGPILNFLRHGKLVLDKDMAE-EGVLEEAEFYNIGPLIRIIKDRMEEK 131


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 42/132 (31%), Positives = 70/132 (53%), Gaps = 7/132 (5%)

Query: 22  GGGLGNKYVQLNVGGSLYYTTVRALTRHDTM----LKAMFSGRMEVLTDKEGWILIDRCG 77
           GGG   ++V+LNVGG+ + TT + L R        L       ++   D+ G  LIDR  
Sbjct: 66  GGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDP 125

Query: 78  KHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKD--SYQPVC 135
            +FG ILNYLR   + + +   E + ++ EA++Y I  LV + +  ++D ++  S  PV 
Sbjct: 126 TYFGPILNYLRHGKLIITKELAE-EGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPVK 184

Query: 136 NIPIITSLKEEE 147
           ++  +   +EEE
Sbjct: 185 HVYRVLQCQEEE 196


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 41/129 (31%), Positives = 73/129 (56%), Gaps = 6/129 (4%)

Query: 24  GLGNKYVQLNVGGSLYYTTVRALTRHD-TMLKAMFSGRMEVLTDKE--GWILIDRCGKHF 80
           G  +K+V+LNVGG+ + TT + L R   + L  +     ++ +DK+  G  LIDR   +F
Sbjct: 40  GSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYF 99

Query: 81  GTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSAL--QDKKDSYQPVCNIP 138
           G +LNYLR   + + ++  E + ++ EA++Y I  L+ + +  +  +D K S  PV ++ 
Sbjct: 100 GPVLNYLRHGKLVINKDLAE-EGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPVKHVY 158

Query: 139 IITSLKEEE 147
            +   +EEE
Sbjct: 159 RVLQCQEEE 167


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 5/97 (5%)

Query: 30  VQLNVGGSLYYTTVRALTRHD-TMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           V+LNVGG  + TT+  L +   + L  MFS   +  TD EG   IDR   +F  IL+YLR
Sbjct: 35  VELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLR 94

Query: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQ 125
              +      Q I E+  EA++Y I+ LV + +   Q
Sbjct: 95  TGQVP----TQHIPEVYREAQFYEIKPLVKLLEDMPQ 127


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 35/140 (25%), Positives = 76/140 (54%), Gaps = 4/140 (2%)

Query: 27  NKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDK-EGWILIDRCGKHFGTIL 84
           N  V ++VGG +Y +++  LT++ D+ +  +F+G   ++ D  +    IDR G+ F  +L
Sbjct: 55  NAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVL 114

Query: 85  NYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQP-VCNIPIITSL 143
           ++LR   + LP + ++   L  EA+YY +Q +V   +   Q+++   +   C+  ++   
Sbjct: 115 SFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVT 174

Query: 144 KE-EERLIESSTKPVVKLLY 162
            +  ER+  S  K +++ ++
Sbjct: 175 PDLGERIALSGEKALIEEVF 194


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 35/140 (25%), Positives = 76/140 (54%), Gaps = 4/140 (2%)

Query: 27  NKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDK-EGWILIDRCGKHFGTIL 84
           N  V ++VGG +Y +++  LT++ D+ +  +F+G   ++ D  +    IDR G+ F  +L
Sbjct: 55  NAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVL 114

Query: 85  NYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQP-VCNIPIITSL 143
           ++LR   + LP + ++   L  EA+YY +Q +V   +   Q+++   +   C+  ++   
Sbjct: 115 SFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVT 174

Query: 144 KE-EERLIESSTKPVVKLLY 162
            +  ER+  S  K +++ ++
Sbjct: 175 PDLGERIALSGEKALIEEVF 194


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 35/140 (25%), Positives = 76/140 (54%), Gaps = 4/140 (2%)

Query: 27  NKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDK-EGWILIDRCGKHFGTIL 84
           N  V ++VGG +Y +++  LT++ D+ +  +F+G   ++ D  +    IDR G+ F  +L
Sbjct: 55  NAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVL 114

Query: 85  NYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQP-VCNIPIITSL 143
           ++LR   + LP + ++   L  EA+YY +Q +V   +   Q+++   +   C+  ++   
Sbjct: 115 SFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVT 174

Query: 144 KE-EERLIESSTKPVVKLLY 162
            +  ER+  S  K +++ ++
Sbjct: 175 PDLGERIALSGEKALIEEVF 194


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 41/122 (33%), Positives = 58/122 (47%), Gaps = 25/122 (20%)

Query: 30  VQLNVGGSLYYTTVRALTR-HDTMLKAMFSG---------RMEVLTDKEGWILIDRCGKH 79
           V+LNVGG +Y T    L    D+ L +MFS          R E+  D      IDR G  
Sbjct: 46  VELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFL 105

Query: 80  FGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNM---------------CQSAL 124
           F  +L+YLRD  + LP++  E + L+ EA+Y+ +  LV +               CQS L
Sbjct: 106 FRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDL 165

Query: 125 QD 126
           +D
Sbjct: 166 ED 167


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 20/113 (17%)

Query: 21  KGGGLGNKY---VQLNVGGSLYYTTVRALTRHDTMLKA-------MFSGRMEVLTD---- 66
           +G  + N +   V+LNVGG +Y+T      RH T++         MFS + +   D    
Sbjct: 15  QGSAVPNSFPEVVELNVGGQVYFT------RHSTLISIPHSLLWKMFSPKRDTANDLAKD 68

Query: 67  KEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNM 119
            +G   IDR G  F  IL+YLRD  + LP +  E   L  EA+Y+ +  LV +
Sbjct: 69  SKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKL 121


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 35/140 (25%), Positives = 74/140 (52%), Gaps = 4/140 (2%)

Query: 27  NKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDK-EGWILIDRCGKHFGTIL 84
           N  V ++VGG +Y +++  LT++ ++ +  +F G   ++ D  +    IDR G+ F  IL
Sbjct: 637 NAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYIL 696

Query: 85  NYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDS-YQPVCNIPIITSL 143
           N+LR   + +P + ++   L  EAKY+ +Q ++   +   QD++   +   C   ++   
Sbjct: 697 NFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVVRVA 756

Query: 144 KE-EERLIESSTKPVVKLLY 162
            +  ER+  S  K +++ ++
Sbjct: 757 PDLGERITLSGDKSLIEEVF 776


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 35/140 (25%), Positives = 74/140 (52%), Gaps = 4/140 (2%)

Query: 27  NKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDK-EGWILIDRCGKHFGTIL 84
           N  V ++VGG +Y +++  LT++ ++ +  +F G   ++ D  +    IDR G+ F  IL
Sbjct: 29  NAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYIL 88

Query: 85  NYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDS-YQPVCNIPIITSL 143
           N+LR   + +P + ++   L  EAKY+ +Q ++   +   QD++   +   C   ++   
Sbjct: 89  NFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVVRVA 148

Query: 144 KE-EERLIESSTKPVVKLLY 162
            +  ER+  S  K +++ ++
Sbjct: 149 PDLGERITLSGDKSLIEEVF 168


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 35/140 (25%), Positives = 74/140 (52%), Gaps = 4/140 (2%)

Query: 27  NKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDK-EGWILIDRCGKHFGTIL 84
           N  V ++VGG +Y +++  LT++ ++ +  +F G   ++ D  +    IDR G+ F  IL
Sbjct: 29  NAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYIL 88

Query: 85  NYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDS-YQPVCNIPIITSL 143
           N+LR   + +P + ++   L  EAKY+ +Q ++   +   QD++   +   C   ++   
Sbjct: 89  NFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVVRVA 148

Query: 144 KE-EERLIESSTKPVVKLLY 162
            +  ER+  S  K +++ ++
Sbjct: 149 PDLGERITLSGDKSLIEEVF 168


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 39/113 (34%), Positives = 56/113 (49%), Gaps = 14/113 (12%)

Query: 19  GFKGGGLGNK-----------YVQLNVGGSLYYTT-VRALTRHDTMLKAMFSGRM--EVL 64
           G  GGG G+             V+LNVGG +Y T     ++  D++L  MF+ +   E+ 
Sbjct: 14  GGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELA 73

Query: 65  TDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLV 117
            D +G   +DR G  F  IL+YLRD  + LP    E   L  EA+Y+ +  LV
Sbjct: 74  RDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELV 126


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 3/112 (2%)

Query: 11  SGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTR-HDTMLKAMFSGRMEVLTDKEG 69
           + A     G    G   + + LNVGG  + T+ + LT   D+   ++ SGR+  L D+ G
Sbjct: 2   AAAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETG 61

Query: 70  WILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQ 121
            I IDR    F  ILN+LR  T  L         L+ EA++Y +  LV   Q
Sbjct: 62  AIFIDRDPTVFAPILNFLR--TKELDPRGVHGSSLLHEAQFYGLTPLVRRLQ 111


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 36/89 (40%), Positives = 48/89 (53%), Gaps = 3/89 (3%)

Query: 30  VQLNVGGSLYYTTVRALTR-HDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           VQLNVGG+ + T+ + L    D+   ++ SGR+  L D+ G I IDR    F  ILN+LR
Sbjct: 20  VQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLR 79

Query: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLV 117
             T  L      I  L  EA++Y I  LV
Sbjct: 80  --TKELDLRGVSINVLRHEAEFYGITPLV 106


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 18/160 (11%)

Query: 3   GDTCLCPASGAKPK--LSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRH--DTMLKAMFS 58
           G+  + P + +KP   L GF        ++ LNVGG  + TT   L     D+ML  MF 
Sbjct: 67  GEPFIDPQTDSKPPEGLLGFH-----TDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFK 121

Query: 59  --GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL 116
             G      D  G  LIDR  ++F  ILNYLR   + +  +   +  ++ EA+++ I  L
Sbjct: 122 DKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQL-IVNDGINLLGVLEEARFFGIDSL 180

Query: 117 VNMCQSALQDKKDSYQPVCNIPIITSLKEEER-LIESSTK 155
           +   + A+   K+S  P  + PI  S KE  R L+ + TK
Sbjct: 181 IEHLEVAI---KNSQPPEDHSPI--SRKEFVRFLLATPTK 215


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 1/91 (1%)

Query: 30  VQLNVGGSLYYTTVRALTRHD-TMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           V LNVGG ++ T    + +   + L  M  GR +      G I +DR G  F  IL++LR
Sbjct: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66

Query: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNM 119
              + LP    +   L  EA +Y ++ LV++
Sbjct: 67  THQLLLPTEFSDYLRLQREALFYELRSLVDL 97


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 1/91 (1%)

Query: 30  VQLNVGGSLYYTTVRALTRHD-TMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88
           V LNVGG ++ T    + +   + L  M  GR +      G I +DR G  F  IL++LR
Sbjct: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66

Query: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNM 119
              + LP    +   L  EA +Y ++ LV++
Sbjct: 67  THQLLLPTEFSDYLRLQREALFYELRSLVDL 97


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 18/160 (11%)

Query: 3   GDTCLCPASGAKPK--LSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRH--DTMLKAMFS 58
           G+  + P + +KP   L GF        ++ L+VGG  + TT   L     D ML  MF 
Sbjct: 67  GEPFIDPQTDSKPPEGLLGFH-----TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFK 121

Query: 59  --GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL 116
             G      D  G  LID+  ++F  ILNYLR   + +  +  ++  ++ EA+++ I  L
Sbjct: 122 DKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQL-IVNDGIDLLGVLEEARFFGIDSL 180

Query: 117 VNMCQSALQDKKDSYQPVCNIPIITSLKEEER-LIESSTK 155
           +   + A+   K+S  P  ++PI  S KE  R L+ + TK
Sbjct: 181 IEHLKVAI---KNSQPPEDHLPI--SRKEFVRCLLATPTK 215


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 18/160 (11%)

Query: 3   GDTCLCPASGAKPK--LSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRH--DTMLKAMFS 58
           G+  + P + +KP   L GF        ++ L+VGG  + TT   L     D ML  MF 
Sbjct: 67  GEPFIDPQTDSKPPEGLLGFH-----TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFK 121

Query: 59  --GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL 116
             G      D  G  LID+  ++F  ILNYLR   + +  +  ++  ++ EA+++ I  L
Sbjct: 122 DKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQL-IVNDGIDLLGVLEEARFFGIDSL 180

Query: 117 VNMCQSALQDKKDSYQPVCNIPIITSLKEEER-LIESSTK 155
           +   + A+   K+S  P  ++PI  S KE  R L+ + TK
Sbjct: 181 IEHLKVAI---KNSQPPEDHLPI--SRKEFVRCLLATPTK 215


>gi|169180181 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 18/160 (11%)

Query: 3   GDTCLCPASGAKPK--LSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRH--DTMLKAMFS 58
           G+  + P + +KP   L GF        ++ L+VGG  + TT   L     D ML  MF 
Sbjct: 67  GEPFIDPQTDSKPPEGLLGFH-----TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFK 121

Query: 59  --GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL 116
             G      D  G  LID+  ++F  ILNYLR   + +  +  ++  ++ EA+++ I  L
Sbjct: 122 DKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQL-IVNDGIDLLGVLEEARFFGIDSL 180

Query: 117 VNMCQSALQDKKDSYQPVCNIPIITSLKEEER-LIESSTK 155
           +   + A+   K+S  P  ++PI  S KE  R L+ + TK
Sbjct: 181 IEHLKVAI---KNSQPPEDHLPI--SRKEFVRCLLATPTK 215


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,563,308
Number of Sequences: 37866
Number of extensions: 482801
Number of successful extensions: 1484
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1420
Number of HSP's gapped (non-prelim): 57
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.