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Search of human proteins with 10863889
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10863889 squamous cell carcinoma antigen recognized by T
cells 1 [Homo sapiens]
(800 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10863889 squamous cell carcinoma antigen recognized by T cell... 1566 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 64 4e-10
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 64 4e-10
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 64 4e-10
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 64 4e-10
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 64 4e-10
gi|148746195 trichohyalin [Homo sapiens] 64 6e-10
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 62 3e-09
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 62 3e-09
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 62 3e-09
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 62 3e-09
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 62 3e-09
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 62 3e-09
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 62 3e-09
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 62 3e-09
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 60 1e-08
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 59 1e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 58 3e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 58 3e-08
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 57 5e-08
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 57 7e-08
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 57 7e-08
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 55 3e-07
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 55 3e-07
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 55 3e-07
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 55 3e-07
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 55 3e-07
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 54 4e-07
gi|31982906 cingulin-like 1 [Homo sapiens] 54 4e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 52 3e-06
>gi|10863889 squamous cell carcinoma antigen recognized by T cells 1
[Homo sapiens]
Length = 800
Score = 1566 bits (4055), Expect = 0.0
Identities = 800/800 (100%), Positives = 800/800 (100%)
Query: 1 MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERG 60
MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERG
Sbjct: 1 MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERG 60
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI
Sbjct: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLL 180
EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLL
Sbjct: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLL 180
Query: 181 NQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEE 240
NQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEE
Sbjct: 181 NQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEE 240
Query: 241 FGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERA 300
FGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERA
Sbjct: 241 FGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERA 300
Query: 301 EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGL 360
EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGL
Sbjct: 301 EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGL 360
Query: 361 RERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRA 420
RERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRA
Sbjct: 361 RERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRA 420
Query: 421 DDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGG 480
DDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGG
Sbjct: 421 DDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGG 480
Query: 481 APPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWE 540
APPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWE
Sbjct: 481 APPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWE 540
Query: 541 EDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDG 600
EDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDG
Sbjct: 541 EDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDG 600
Query: 601 EENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVAR 660
EENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVAR
Sbjct: 601 EENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVAR 660
Query: 661 VKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKL 720
VKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKL
Sbjct: 661 VKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKL 720
Query: 721 TPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQK 780
TPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQK
Sbjct: 721 TPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQK 780
Query: 781 TPYIVLSGSGKSMNANTITK 800
TPYIVLSGSGKSMNANTITK
Sbjct: 781 TPYIVLSGSGKSMNANTITK 800
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 64.3 bits (155), Expect = 4e-10
Identities = 172/786 (21%), Positives = 309/786 (39%), Gaps = 107/786 (13%)
Query: 54 KRSRERGGERGSGRRGAEAEA-RSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSS 112
+R+ E+ G E EA ++ S A E R KRE+ + A +T S
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1189
Query: 113 GDAS--------SLSIEE-TNKL----RAKLGL----KPLE------------VNAIKKE 143
+A + ++EE T +L RAK L + LE + K+E
Sbjct: 1190 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Query: 144 AGTKEEPVTADVINPMAL-----RQREELREKLAAAKEK-----RLLNQKLGKIKTLGED 193
K++ + A V + R R EL +K+ + + +LN+ GK L +D
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 194 ----DPWLDDTAAWI-ERSRQL----QKEKDLAEKRAKLLEEMDQEFGVSTLVE------ 238
L DT + E +RQ K + L E+R L +++D+E +E
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
Query: 239 -----------EEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTL-KDKGVLQEEE 286
++F + L + +E+ + E L K K LQ+E
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
Query: 287 DVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERP 346
D LV V+L ++ + N+E +++K D L E A ++ R+ ++E +
Sbjct: 1430 DDLV-VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA-LS 1487
Query: 347 HSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRV 406
+ LE+ A ER + ++A++ S VG + + + T + +
Sbjct: 1488 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ 1547
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDT 466
+ + E + A L + Q G F L+ R + EE++ + + L +T
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN----EEKRRQLQRQLHEYET 1603
Query: 467 RVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLE-KGR-----RLRQLQ------- 513
+E DE + A + + LE D +LELQ KGR +LR+LQ
Sbjct: 1604 ELE-----DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1658
Query: 514 -QLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLA 572
+L+ R S +++ K+ E + + E D ++ + E LA
Sbjct: 1659 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 1718
Query: 573 GNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEP 632
+ + L D +R E E EE ++ K Q S + E
Sbjct: 1719 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 1778
Query: 633 IVNRGLAAALLL-CQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRRE-- 689
+ +A L QNK L + VK+ K S + +E K+A ++ +E
Sbjct: 1779 TAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK---STIAALEAKIAQLEEQVEQEAR 1835
Query: 690 EYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMK-TERRMK 748
E + T+ K+KD ++ ++ DE RK+ E +++ + KG+ ++K +R+++
Sbjct: 1836 EKQAATKSLKQKDKKLKEILLQVEDE--RKMA--EQYKEQAE----KGNARVKQLKRQLE 1887
Query: 749 KLDEEA 754
+ +EE+
Sbjct: 1888 EAEEES 1893
Score = 46.6 bits (109), Expect = 9e-05
Identities = 115/531 (21%), Positives = 211/531 (39%), Gaps = 93/531 (17%)
Query: 96 EKRDDGYEAAASSKTSSGDASSLS--IEETNKLRAKLGLKPLEVNA-IKKEAGTKEEPVT 152
E+ D G + A K + L +EE R KL L+ + A IKK ++E +
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK---LEDEILV 989
Query: 153 ADVINPMALRQREELREKLA------AAKEKRLLNQKLGKIKTLGEDD-PWLDDTAAWIE 205
D N ++R+ L E+++ A +E++ N L K+K E L+ E
Sbjct: 990 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN--LTKLKNKHESMISELEVRLKKEE 1047
Query: 206 RSRQ-LQKEK-------------------DLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
+SRQ L+K K +AE + +L ++ ++ +++E Q+
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 246 QDLYSARDLQG--------LTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDK 297
L R+L+G L E A + E + L + + + E ED L + +
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 298 ERA--EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELE---------GERP 346
RA E+ V + KK D + + V ++ +QK + + E+LE +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEM-RQKHAQAVEELTEQLEQFKRAKANLDKNK 1226
Query: 347 HSFRLEQGGTADGLR-----ERELEEIRAKLRLQAQSLSTV---GPRLASEYLTPEEMVT 398
+ E A LR ++E+E + KL Q Q L + G R +E L +
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE-LNDKVHKL 1285
Query: 399 FKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVS----EVEEEK 454
+ + + + E + + A D+ L Q QD + R + VS ++EEE+
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 455 EPVPQPLPSDDTRVENMD---------ISDEEEGGAPPPGSPQVLEEDEAELELQ----- 500
+ L + +N++ +SD ++ + + LEE + + +
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Query: 501 ----------KQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEE 541
+LEK + R Q+L L + ++V LE +QR +++
Sbjct: 1406 QQYEEKAAAYDKLEKTKN-RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1455
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 64.3 bits (155), Expect = 4e-10
Identities = 172/786 (21%), Positives = 309/786 (39%), Gaps = 107/786 (13%)
Query: 54 KRSRERGGERGSGRRGAEAEA-RSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSS 112
+R+ E+ G E EA ++ S A E R KRE+ + A +T S
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1196
Query: 113 GDAS--------SLSIEE-TNKL----RAKLGL----KPLE------------VNAIKKE 143
+A + ++EE T +L RAK L + LE + K+E
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Query: 144 AGTKEEPVTADVINPMAL-----RQREELREKLAAAKEK-----RLLNQKLGKIKTLGED 193
K++ + A V + R R EL +K+ + + +LN+ GK L +D
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 194 ----DPWLDDTAAWI-ERSRQL----QKEKDLAEKRAKLLEEMDQEFGVSTLVE------ 238
L DT + E +RQ K + L E+R L +++D+E +E
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1376
Query: 239 -----------EEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTL-KDKGVLQEEE 286
++F + L + +E+ + E L K K LQ+E
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1436
Query: 287 DVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERP 346
D LV V+L ++ + N+E +++K D L E A ++ R+ ++E +
Sbjct: 1437 DDLV-VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA-LS 1494
Query: 347 HSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRV 406
+ LE+ A ER + ++A++ S VG + + + T + +
Sbjct: 1495 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ 1554
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDT 466
+ + E + A L + Q G F L+ R + EE++ + + L +T
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN----EEKRRQLQRQLHEYET 1610
Query: 467 RVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLE-KGR-----RLRQLQ------- 513
+E DE + A + + LE D +LELQ KGR +LR+LQ
Sbjct: 1611 ELE-----DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1665
Query: 514 -QLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLA 572
+L+ R S +++ K+ E + + E D ++ + E LA
Sbjct: 1666 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 1725
Query: 573 GNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEP 632
+ + L D +R E E EE ++ K Q S + E
Sbjct: 1726 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 1785
Query: 633 IVNRGLAAALLL-CQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRRE-- 689
+ +A L QNK L + VK+ K S + +E K+A ++ +E
Sbjct: 1786 TAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK---STIAALEAKIAQLEEQVEQEAR 1842
Query: 690 EYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMK-TERRMK 748
E + T+ K+KD ++ ++ DE RK+ E +++ + KG+ ++K +R+++
Sbjct: 1843 EKQAATKSLKQKDKKLKEILLQVEDE--RKMA--EQYKEQAE----KGNARVKQLKRQLE 1894
Query: 749 KLDEEA 754
+ +EE+
Sbjct: 1895 EAEEES 1900
Score = 46.6 bits (109), Expect = 9e-05
Identities = 115/531 (21%), Positives = 211/531 (39%), Gaps = 93/531 (17%)
Query: 96 EKRDDGYEAAASSKTSSGDASSLS--IEETNKLRAKLGLKPLEVNA-IKKEAGTKEEPVT 152
E+ D G + A K + L +EE R KL L+ + A IKK ++E +
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK---LEDEILV 996
Query: 153 ADVINPMALRQREELREKLA------AAKEKRLLNQKLGKIKTLGEDD-PWLDDTAAWIE 205
D N ++R+ L E+++ A +E++ N L K+K E L+ E
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN--LTKLKNKHESMISELEVRLKKEE 1054
Query: 206 RSRQ-LQKEK-------------------DLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
+SRQ L+K K +AE + +L ++ ++ +++E Q+
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 246 QDLYSARDLQG--------LTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDK 297
L R+L+G L E A + E + L + + + E ED L + +
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 298 ERA--EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELE---------GERP 346
RA E+ V + KK D + + V ++ +QK + + E+LE +
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEM-RQKHAQAVEELTEQLEQFKRAKANLDKNK 1233
Query: 347 HSFRLEQGGTADGLR-----ERELEEIRAKLRLQAQSLSTV---GPRLASEYLTPEEMVT 398
+ E A LR ++E+E + KL Q Q L + G R +E L +
Sbjct: 1234 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE-LNDKVHKL 1292
Query: 399 FKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVS----EVEEEK 454
+ + + + E + + A D+ L Q QD + R + VS ++EEE+
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 455 EPVPQPLPSDDTRVENMD---------ISDEEEGGAPPPGSPQVLEEDEAELELQ----- 500
+ L + +N++ +SD ++ + + LEE + + +
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412
Query: 501 ----------KQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEE 541
+LEK + R Q+L L + ++V LE +QR +++
Sbjct: 1413 QQYEEKAAAYDKLEKTKN-RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 64.3 bits (155), Expect = 4e-10
Identities = 172/786 (21%), Positives = 309/786 (39%), Gaps = 107/786 (13%)
Query: 54 KRSRERGGERGSGRRGAEAEA-RSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSS 112
+R+ E+ G E EA ++ S A E R KRE+ + A +T S
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1196
Query: 113 GDAS--------SLSIEE-TNKL----RAKLGL----KPLE------------VNAIKKE 143
+A + ++EE T +L RAK L + LE + K+E
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Query: 144 AGTKEEPVTADVINPMAL-----RQREELREKLAAAKEK-----RLLNQKLGKIKTLGED 193
K++ + A V + R R EL +K+ + + +LN+ GK L +D
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 194 ----DPWLDDTAAWI-ERSRQL----QKEKDLAEKRAKLLEEMDQEFGVSTLVE------ 238
L DT + E +RQ K + L E+R L +++D+E +E
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1376
Query: 239 -----------EEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTL-KDKGVLQEEE 286
++F + L + +E+ + E L K K LQ+E
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1436
Query: 287 DVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERP 346
D LV V+L ++ + N+E +++K D L E A ++ R+ ++E +
Sbjct: 1437 DDLV-VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA-LS 1494
Query: 347 HSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRV 406
+ LE+ A ER + ++A++ S VG + + + T + +
Sbjct: 1495 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ 1554
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDT 466
+ + E + A L + Q G F L+ R + EE++ + + L +T
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN----EEKRRQLQRQLHEYET 1610
Query: 467 RVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLE-KGR-----RLRQLQ------- 513
+E DE + A + + LE D +LELQ KGR +LR+LQ
Sbjct: 1611 ELE-----DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1665
Query: 514 -QLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLA 572
+L+ R S +++ K+ E + + E D ++ + E LA
Sbjct: 1666 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 1725
Query: 573 GNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEP 632
+ + L D +R E E EE ++ K Q S + E
Sbjct: 1726 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 1785
Query: 633 IVNRGLAAALLL-CQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRRE-- 689
+ +A L QNK L + VK+ K S + +E K+A ++ +E
Sbjct: 1786 TAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK---STIAALEAKIAQLEEQVEQEAR 1842
Query: 690 EYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMK-TERRMK 748
E + T+ K+KD ++ ++ DE RK+ E +++ + KG+ ++K +R+++
Sbjct: 1843 EKQAATKSLKQKDKKLKEILLQVEDE--RKMA--EQYKEQAE----KGNARVKQLKRQLE 1894
Query: 749 KLDEEA 754
+ +EE+
Sbjct: 1895 EAEEES 1900
Score = 46.6 bits (109), Expect = 9e-05
Identities = 115/531 (21%), Positives = 211/531 (39%), Gaps = 93/531 (17%)
Query: 96 EKRDDGYEAAASSKTSSGDASSLS--IEETNKLRAKLGLKPLEVNA-IKKEAGTKEEPVT 152
E+ D G + A K + L +EE R KL L+ + A IKK ++E +
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK---LEDEILV 996
Query: 153 ADVINPMALRQREELREKLA------AAKEKRLLNQKLGKIKTLGEDD-PWLDDTAAWIE 205
D N ++R+ L E+++ A +E++ N L K+K E L+ E
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN--LTKLKNKHESMISELEVRLKKEE 1054
Query: 206 RSRQ-LQKEK-------------------DLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
+SRQ L+K K +AE + +L ++ ++ +++E Q+
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 246 QDLYSARDLQG--------LTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDK 297
L R+L+G L E A + E + L + + + E ED L + +
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 298 ERA--EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELE---------GERP 346
RA E+ V + KK D + + V ++ +QK + + E+LE +
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEM-RQKHAQAVEELTEQLEQFKRAKANLDKNK 1233
Query: 347 HSFRLEQGGTADGLR-----ERELEEIRAKLRLQAQSLSTV---GPRLASEYLTPEEMVT 398
+ E A LR ++E+E + KL Q Q L + G R +E L +
Sbjct: 1234 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE-LNDKVHKL 1292
Query: 399 FKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVS----EVEEEK 454
+ + + + E + + A D+ L Q QD + R + VS ++EEE+
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 455 EPVPQPLPSDDTRVENMD---------ISDEEEGGAPPPGSPQVLEEDEAELELQ----- 500
+ L + +N++ +SD ++ + + LEE + + +
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412
Query: 501 ----------KQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEE 541
+LEK + R Q+L L + ++V LE +QR +++
Sbjct: 1413 QQYEEKAAAYDKLEKTKN-RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 64.3 bits (155), Expect = 4e-10
Identities = 172/786 (21%), Positives = 309/786 (39%), Gaps = 107/786 (13%)
Query: 54 KRSRERGGERGSGRRGAEAEA-RSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSS 112
+R+ E+ G E EA ++ S A E R KRE+ + A +T S
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1189
Query: 113 GDAS--------SLSIEE-TNKL----RAKLGL----KPLE------------VNAIKKE 143
+A + ++EE T +L RAK L + LE + K+E
Sbjct: 1190 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Query: 144 AGTKEEPVTADVINPMAL-----RQREELREKLAAAKEK-----RLLNQKLGKIKTLGED 193
K++ + A V + R R EL +K+ + + +LN+ GK L +D
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 194 ----DPWLDDTAAWI-ERSRQL----QKEKDLAEKRAKLLEEMDQEFGVSTLVE------ 238
L DT + E +RQ K + L E+R L +++D+E +E
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
Query: 239 -----------EEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTL-KDKGVLQEEE 286
++F + L + +E+ + E L K K LQ+E
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
Query: 287 DVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERP 346
D LV V+L ++ + N+E +++K D L E A ++ R+ ++E +
Sbjct: 1430 DDLV-VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA-LS 1487
Query: 347 HSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRV 406
+ LE+ A ER + ++A++ S VG + + + T + +
Sbjct: 1488 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ 1547
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDT 466
+ + E + A L + Q G F L+ R + EE++ + + L +T
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN----EEKRRQLQRQLHEYET 1603
Query: 467 RVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLE-KGR-----RLRQLQ------- 513
+E DE + A + + LE D +LELQ KGR +LR+LQ
Sbjct: 1604 ELE-----DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1658
Query: 514 -QLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLA 572
+L+ R S +++ K+ E + + E D ++ + E LA
Sbjct: 1659 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 1718
Query: 573 GNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEP 632
+ + L D +R E E EE ++ K Q S + E
Sbjct: 1719 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 1778
Query: 633 IVNRGLAAALLL-CQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRRE-- 689
+ +A L QNK L + VK+ K S + +E K+A ++ +E
Sbjct: 1779 TAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK---STIAALEAKIAQLEEQVEQEAR 1835
Query: 690 EYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMK-TERRMK 748
E + T+ K+KD ++ ++ DE RK+ E +++ + KG+ ++K +R+++
Sbjct: 1836 EKQAATKSLKQKDKKLKEILLQVEDE--RKMA--EQYKEQAE----KGNARVKQLKRQLE 1887
Query: 749 KLDEEA 754
+ +EE+
Sbjct: 1888 EAEEES 1893
Score = 46.6 bits (109), Expect = 9e-05
Identities = 115/531 (21%), Positives = 211/531 (39%), Gaps = 93/531 (17%)
Query: 96 EKRDDGYEAAASSKTSSGDASSLS--IEETNKLRAKLGLKPLEVNA-IKKEAGTKEEPVT 152
E+ D G + A K + L +EE R KL L+ + A IKK ++E +
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK---LEDEILV 989
Query: 153 ADVINPMALRQREELREKLA------AAKEKRLLNQKLGKIKTLGEDD-PWLDDTAAWIE 205
D N ++R+ L E+++ A +E++ N L K+K E L+ E
Sbjct: 990 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN--LTKLKNKHESMISELEVRLKKEE 1047
Query: 206 RSRQ-LQKEK-------------------DLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
+SRQ L+K K +AE + +L ++ ++ +++E Q+
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 246 QDLYSARDLQG--------LTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDK 297
L R+L+G L E A + E + L + + + E ED L + +
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 298 ERA--EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELE---------GERP 346
RA E+ V + KK D + + V ++ +QK + + E+LE +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEM-RQKHAQAVEELTEQLEQFKRAKANLDKNK 1226
Query: 347 HSFRLEQGGTADGLR-----ERELEEIRAKLRLQAQSLSTV---GPRLASEYLTPEEMVT 398
+ E A LR ++E+E + KL Q Q L + G R +E L +
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE-LNDKVHKL 1285
Query: 399 FKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVS----EVEEEK 454
+ + + + E + + A D+ L Q QD + R + VS ++EEE+
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 455 EPVPQPLPSDDTRVENMD---------ISDEEEGGAPPPGSPQVLEEDEAELELQ----- 500
+ L + +N++ +SD ++ + + LEE + + +
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Query: 501 ----------KQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEE 541
+LEK + R Q+L L + ++V LE +QR +++
Sbjct: 1406 QQYEEKAAAYDKLEKTKN-RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1455
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 64.3 bits (155), Expect = 4e-10
Identities = 109/532 (20%), Positives = 210/532 (39%), Gaps = 73/532 (13%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
E E +S + +ER + E +E K +++D +A + K D EE R +
Sbjct: 148 EKEEKSESR-QERYEIEETETVTKSYQKNDWRDAEENKKE---DKEKEEEEEEKPKRGSI 203
Query: 131 GLKPLEVNAIKKEAGTKEEPVTADVIN-------PMALRQREELREKL------------ 171
G +EV +K ++EE V + N P +RE+ +++
Sbjct: 204 GENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263
Query: 172 -AAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQL---QKEKDLAEKRAKLLEEM 227
A A+ RL ++ +IK E D + D A IE + ++E+ AE+R ++ EE
Sbjct: 264 RAEAERARLEAEERERIKA--EQDKKIADERARIEAEEKAAAQERERREAEERERMREEE 321
Query: 228 DQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEED 287
+ ++EE + ++ ++ + E +E E + + +EEE
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER-QRIKEEEKRAAEERQRARAEEEEK 380
Query: 288 VLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPH 347
V E ++N +L +KK A Q+ + K ++++EG+ +
Sbjct: 381 AKV-------EEQKRNKQLEEKKH--------------AMQETKIKGEKVEQKIEGKWVN 419
Query: 348 SFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVK 407
+ ++ + +++ EE K++ + + L P E + E++ K+ K VK
Sbjct: 420 EKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK 479
Query: 408 KIRKKEK---EVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSD 464
++K EV + + + + + F R GR V E E P +
Sbjct: 480 SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFS---RPGGRASVDTKEAEGAPQVEA---- 532
Query: 465 DTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEK 524
R+E + E E +E E QKQ E L +L++ ++ R +
Sbjct: 533 GKRLEELRRRRGET------------ESEEFEKLKQKQQEAALELEELKKKREERRKVLE 580
Query: 525 VVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNRE 576
E +K E R E+E+ R + +E ++P GL+ +++
Sbjct: 581 EEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Score = 61.2 bits (147), Expect = 4e-09
Identities = 114/544 (20%), Positives = 219/544 (40%), Gaps = 82/544 (15%)
Query: 73 EARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGL 132
E R ++R + R+ ++ DD E AA + L ++ + ++
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQV-T 63
Query: 133 KPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRL--LNQKLGKIKTL 190
+EVNA + + EE T + E+LA +E+R L + L + K
Sbjct: 64 DQVEVNA--QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK-- 119
Query: 191 GEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYS 250
E DP + D + + SR++Q D AE T +EE + RQ+ Y
Sbjct: 120 -EFDPTITDASLSLP-SRRMQN--DTAENE--------------TTEKEEKSESRQERYE 161
Query: 251 ARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKK 310
+ + +T + + +R+ E K+K +EEE+ + + + E VE + +
Sbjct: 162 IEETETVTKSYQKNDWRDAEENKKEDKEK---EEEEEEKPKRGSIGENQVEVMVEEKTTE 218
Query: 311 PDYLPYAEDESVDDLAQQKPRSILSKYDEELE---GERPHSFRLEQGGTADGLRERELEE 367
E+ V L + S K +EE E E H ++E+ ER E
Sbjct: 219 SQ-----EETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE 273
Query: 368 IRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLG 427
+ R++A+ + A + EE ++ +RR + R++ +E RA
Sbjct: 274 AEERERIKAEQDKKIADERAR--IEAEEKAAAQERERREAEERERMREEEKRA------- 324
Query: 428 DQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRV--ENMDISDEEEGGAPPPG 485
R+R+ E E+ Q + ++ R E I +EE+ A
Sbjct: 325 -------------AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 371
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQ----LQQLRDSGEKVVEIVKKLESRQRGWEE 541
+ EE++A++E QK R +QL++ +Q+ + GEKV + K+E + ++
Sbjct: 372 RARAEEEEKAKVEEQK------RNKQLEEKKHAMQETKIKGEKVEQ---KIEGKWVNEKK 422
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREE-QEELMDFERDEERSANGGSESDG 600
++ + + A++ + GE + RE+ QE+ F+++E + + +
Sbjct: 423 AQEDKLQTAVL--------KKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEP 474
Query: 601 EENI 604
+E +
Sbjct: 475 KEEV 478
Score = 52.0 bits (123), Expect = 2e-06
Identities = 97/490 (19%), Positives = 198/490 (40%), Gaps = 92/490 (18%)
Query: 51 ERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKT 110
ER + E+ + R EAE +++ RER +AE ER + EKR AA +
Sbjct: 276 ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKR------AAEERQ 329
Query: 111 SSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREK 170
+ + EE +++ + E A ++ KEE ++ E R++
Sbjct: 330 RIKEEEKRAAEERQRIKEE------EKRAAEERQRIKEEE-----------KRAAEERQR 372
Query: 171 LAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQE 230
A +E++ ++ + K L E + +T E+ Q + K + EK+A QE
Sbjct: 373 ARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKA-------QE 425
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLV 290
+ T V ++ G+ + A+ + ++ +F++ E +KD+ + +++E
Sbjct: 426 DKLQTAVLKKQGEEKGTKVQAKREK---LQEDKPTFKKEE-----IKDEKIKKDKEPKEE 477
Query: 291 NVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEE-----LEGER 345
+ +D+++ E++ + +++ + + + ++ R+ + + E G+R
Sbjct: 478 VKSFMDRKKG--FTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR 535
Query: 346 PHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRR 405
R +G T E E+++ K + A L + + EE +K +
Sbjct: 536 LEELRRRRGET----ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA 591
Query: 406 VKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDD 465
+K+R++E++ RL+ RR +E E+++ +P+ SDD
Sbjct: 592 DRKLREEEEK---------------------RRLKEEIERRRAEAAEKRQKMPEDGLSDD 630
Query: 466 TRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKV 525
+ P GS +EE AE L K ++K ++ Q
Sbjct: 631 KKPFKC---------FTPKGSSLKIEE-RAEF-LNKSVQKSSGVKSTHQ----------- 668
Query: 526 VEIVKKLESR 535
IV K++SR
Sbjct: 669 AAIVSKIDSR 678
Score = 42.4 bits (98), Expect = 0.002
Identities = 94/459 (20%), Positives = 186/459 (40%), Gaps = 60/459 (13%)
Query: 361 RERELE-EIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKE---- 415
R REL + R ++RL+A+ R+A + +E ++ +RR ++ R ++K+
Sbjct: 6 RRRELRRQKREEMRLEAE-------RIAYQRNDDDEEEAARERRRRARQERLRQKQEEES 58
Query: 416 -------VVVRADDLLPLGD------QTQ-DGD----FGSRLRGRGRRRVSEVEEEKEPV 457
V V A + +P + TQ +GD F RL R RR ++E E
Sbjct: 59 LGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQ 118
Query: 458 PQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQK--QLEKGRRLRQLQQL 515
+ D + + +S + E++E Q+ ++E+ + + Q
Sbjct: 119 KE----FDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174
Query: 516 QQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATS---EFCRTLGEIPTYGLA 572
RD+ E K E +++ EE+E P+R G+I N E T + T ++
Sbjct: 175 NDWRDAEEN------KKEDKEKEEEEEEKPKR-GSIGENQVEVMVEEKTTESQEETVVMS 227
Query: 573 ---GNREEQEELMDFERDE---ERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTT 626
G +E + ER++ E S + E + +E L+ E++++ +
Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKK 287
Query: 627 ILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYS 686
I DE + AA Q + E ++ R + + E+K A +++
Sbjct: 288 IADERARIEAEEKAA---AQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQR 344
Query: 687 RREEYRGFTQDFK-----EKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKM 741
+EE + ++ + EK + + +E K+ ++ +QL + H K+
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI 404
Query: 742 KTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQK 780
K E+ +K++ + + +K + D V Q ++K K
Sbjct: 405 KGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK 443
Score = 34.7 bits (78), Expect = 0.36
Identities = 55/333 (16%), Positives = 121/333 (36%), Gaps = 10/333 (3%)
Query: 31 RHREHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSE 90
R R + + R E R+R +E R+ + E + + R+R + E E
Sbjct: 306 RERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEE--E 363
Query: 91 RRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEP 150
+R E++ E +K + +EE + +K +V + E+
Sbjct: 364 KRAAEERQRARAEEEEKAKVEE-QKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422
Query: 151 VTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQL 210
D + L+++ E + AK ++L K K +D+ D E +
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFM 482
Query: 211 QKEKDLAEKRAKLLEEMDQEF-GVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREG 269
++K E +++ E M + G+ D A + ++ R
Sbjct: 483 DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR 542
Query: 270 ETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQK 329
+ + + + Q++++ + + + K+R E+ L +++ D + + +++
Sbjct: 543 RGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKR 602
Query: 330 PRSILSKYDEELEGERPHSFRLEQGGTADGLRE 362
+ EE+E R + Q DGL +
Sbjct: 603 ------RLKEEIERRRAEAAEKRQKMPEDGLSD 629
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 63.9 bits (154), Expect = 6e-10
Identities = 152/722 (21%), Positives = 275/722 (38%), Gaps = 129/722 (17%)
Query: 51 ERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSK- 109
+R KR R + E E R R R Q E E+R+KRE+ ++ E +
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLR-REQQERREQRLKREEEEERLEQRLKREH 676
Query: 110 TSSGDASSLSIEETNKLRAKLGLK-PLEVNAIKKEAGTKEEPVTADVINPMALRQREELR 168
L+ EE + R ++ + P ++ EA ++ V + R+R+E
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736
Query: 169 EKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAW-----IERSRQ-LQKEKDLAEKRAK 222
EK + + ++ + E++ D T W ER RQ L L E+R +
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796
Query: 223 LL---EEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDK 279
L E +E EE+ +RRQ ++LQ F E E + +
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ----------FLEEEEQLQRRERA 846
Query: 280 GVLQEEEDVLVNVNLVDKERAEKNVELR-----------KKKPDYLPYAEDESVDDLAQQ 328
LQEEED L D+ER + R +K+ + YA+ + L +
Sbjct: 847 QQLQEEEDGLQE----DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL--R 900
Query: 329 KPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLAS 388
K + +L + +EEL+ E R R+ + + R + +LQ +
Sbjct: 901 KEQQLLQEEEEELQREEREKRR----------RQEQERQYREEEQLQQEE---------- 940
Query: 389 EYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVS 448
E+++ ++ KRR ++E+E R D L ++ G+ + R + R +
Sbjct: 941 -----EQLLREEREKRR-----RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 449 EVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRR 508
EEE + EEE Q+L E+ + Q+ + R+
Sbjct: 991 REEEE-------------------LQQEEE---------QLLREEREKRRRQEWERQYRK 1022
Query: 509 LRQLQQLQQ--LRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEI 566
+LQQ ++ LR+ EK ++L+ R+R + E+E+ +++ + E R
Sbjct: 1023 KDELQQEEEQLLREEREK-----RRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Query: 567 PTYGLAGN-REEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEE----------- 614
Y ++E+E+L+ E ++ R + EE + L E
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE 1137
Query: 615 ---KQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSA 671
+++++ +L EEP R + + L + Q + + +
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 672 VYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPD----VKIEYVDETGRKLTPKEAFR 727
Y E+++ + R++ YR Q K ++P+ V+ V GR+ E FR
Sbjct: 1198 QYREEEEL---QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE---NEQFR 1251
Query: 728 QL 729
QL
Sbjct: 1252 QL 1253
Score = 60.5 bits (145), Expect = 6e-09
Identities = 115/608 (18%), Positives = 246/608 (40%), Gaps = 96/608 (15%)
Query: 27 EQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQA 86
+Q R +E ++H+ + E+ +R + E+ R + E + H +ER +
Sbjct: 423 QQLRREQEEERHEQKH--------EQERREQRLKREQEERRDWLKREEETERHEQERRKQ 474
Query: 87 EPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGT 146
+ +R + E+R+ + + + + + R + LK E ++
Sbjct: 475 Q-LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 147 KEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIER 206
E+ + R++EE RE+L +E++ L Q+ R
Sbjct: 534 SEQQLR---------REQEERREQLLKREEEKRLEQE---------------------RR 563
Query: 207 SRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSF 266
++L++E++ E+R +LL+ EEE Q+R L+ ++
Sbjct: 564 EQRLKREQE--ERRDQLLKR-----------EEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 267 REGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLA 326
+ E LK + +E L+ +++ + +LR++
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLK---SEEQEERRQQQLRRE----------------- 650
Query: 327 QQKPRSILSKYDEELEG-----ERPHSFRLEQGGTADGLRERELEEIRAKL-RLQAQSLS 380
QQ+ R K +EE E +R H + A+ +E+ E I++++ + Q Q S
Sbjct: 651 QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 710
Query: 381 TVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQD--GDF--- 435
R + Y P + ++ + + +K R++E E+ + ++ Q ++ DF
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
Query: 436 --GSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEED 493
RGR+R+S +E + L +++ + EEE + E++
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
Query: 494 EAELELQKQLEKGRRLRQLQQLQQ-LRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIV 552
LE ++QL++ R +QLQ+ + L++ E+ ++ + + R W+ +E+ +R+ +
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR-WQLEEERKRRRHTL 889
Query: 553 F--NATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVN 610
+ A E R ++ +EE+EEL ER++ R + EE +
Sbjct: 890 YAKPALQEQLRKEQQL-------LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 611 LDEEKQQQ 618
L E++++
Sbjct: 943 LLREEREK 950
Score = 54.3 bits (129), Expect = 4e-07
Identities = 110/536 (20%), Positives = 224/536 (41%), Gaps = 55/536 (10%)
Query: 27 EQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQA 86
E+ R R+ ++ ++R + +++ + GE RR E E + RE +
Sbjct: 947 EREKRRRQERERQYRKDK------KLQQKEEQLLGEEPEKRRRQEREKKY----REEEEL 996
Query: 87 EPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIK----K 142
+ E ++ RE+R+ + D L EE LR + + L+ + +
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYREEE 1054
Query: 143 EAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAA 202
E +EE + + R+R+EL + KE+ L ++ + L ++P +
Sbjct: 1055 ELQQEEEQLLGE---ERETRRRQELERQYR--KEEELQQEE----EQLLREEP---EKRR 1102
Query: 203 WIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLV----EEEFGQRRQDLYSARDLQGLT 258
ER RQ ++E++L ++ +LL E ++ L EEE Q+ ++ + +
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 259 VEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAE 318
+ +RE E L +++ +L+EE++ + R E+ ++ +K+K Y E
Sbjct: 1163 RQELERQYREEEE--LQQEEEQLLREEQEKR-RQERERQYREEEELQRQKRKQRYRD--E 1217
Query: 319 DESVDDLAQQKPRSILSKYDEEL--EGERPHSFR-LEQGGTADGLRERELEEIRAKLRLQ 375
D+ D Q +P + D ++ +G FR LE D +++L+ + + + +
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
Query: 376 AQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDF 435
+ + + EE + ++ K ++ RK ++E + L ++ ++
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL-------LREEREE--- 1327
Query: 436 GSRLRGRGRRRVSEVEE---EKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEE 492
R R R+ E E+ E+E P D + ++ +E+G Q L
Sbjct: 1328 -KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE-EEQRLRR 1385
Query: 493 DEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
E E + K+ ++ R + QQL+Q RD + E + R R + E+E R+
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441
Score = 53.5 bits (127), Expect = 7e-07
Identities = 118/577 (20%), Positives = 231/577 (40%), Gaps = 71/577 (12%)
Query: 49 GGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASS 108
G RR++ +E+ E G +E + R R+R E +R + ++R++
Sbjct: 134 GQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL 193
Query: 109 KTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELR 168
++ G + +E R +L LE+ +E ++ D + + R
Sbjct: 194 QSCKGHETEEFPDEEQLRRREL----LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR 249
Query: 169 EKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAW-IERSRQLQKEKDLAEKRAKLLEEM 227
E + +E++L ++ + + L E++ L + R RQ ++++ +R + L
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 228 DQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEED 287
+E E Q R++ R Q L E + RE + L+ E++
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQ--EERREQQ-----------LRREQE 356
Query: 288 VLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPH 347
+ +E+ E+ E + ++ L E QQ R + +++L R
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQL---RREQQLRREQQLRREQQLRREQQL--RREQ 411
Query: 348 SFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASE---YLTPEEMVTFKKTKR 404
R EQ + RE EE R + + + + R E +L EE + +R
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
Query: 405 RVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSD 464
R +++++ ++E R + L L ++ + R + RR ++ E+E
Sbjct: 472 RKQQLKRDQEE--ERRERWLKLEEEER--------REQQERREQQLRREQE--------- 512
Query: 465 DTRVENMDISDEEEGGAPPPGSPQVL--EEDEAELELQKQLEKGRRLRQLQQLQQL-RDS 521
+ R + + +EEE S Q L E++E +L K+ E+ +RL Q ++ Q+L R+
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR-EEEKRLEQERREQRLKREQ 571
Query: 522 GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEEL 581
E+ +++K+ E R++ + E ER + REE E L
Sbjct: 572 EERRDQLLKREEERRQQRLKREQEERLEQRL---------------------KREEVERL 610
Query: 582 MDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQ 618
ER E+R E + + + + +E +QQQ
Sbjct: 611 EQEERREQRLKREEPEEERRQQL-LKSEEQEERRQQQ 646
Score = 50.1 bits (118), Expect = 8e-06
Identities = 101/450 (22%), Positives = 185/450 (41%), Gaps = 98/450 (21%)
Query: 194 DPWLDDTAAWIERSRQLQKEKDLAE-----KRAKLLEEMDQEFGVSTLVEEEFGQRRQDL 248
D L++ R ++ ++E++LAE ++ + LE+ D++ +EE ++RQ+
Sbjct: 126 DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRR-----DEELWRQRQEW 180
Query: 249 YSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRK 308
+ + E + S + ET D+ L+ E + L K R EK + R+
Sbjct: 181 QEREERRA--EEEQLQSCKGHETE--EFPDEEQLRRRE----LLELRRKGREEKQQQ-RR 231
Query: 309 KKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEI 368
++ D + E+E +K ++L K +E+L+ E P R+REL+E
Sbjct: 232 ERQDRVFQEEEEK----EWRKRETVLRKEEEKLQEEEPQ-------------RQRELQEE 274
Query: 369 RAKLR-LQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLG 427
+LR L+ Q L +E ++ RR +++R+K++E R +
Sbjct: 275 EEQLRKLERQELRR----------ERQEEEQQQQRLRREQQLRRKQEEE--RREQ----- 317
Query: 428 DQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
Q + + R + RR ++ E+E + R + + EEE
Sbjct: 318 -QEERREQQERREQQEERREQQLRREQE---------ERREQQLRREQEEERREQQLRRE 367
Query: 488 QVLEEDEAELELQKQLEKGRRLRQLQQL---------QQLRDSGEKVVEIVKKLESRQRG 538
Q E E +L ++QL + ++LR+ QQL QQLR + E + E + R
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSE- 597
+E+E E+K E R + + EQEE D+ + EE + E
Sbjct: 428 EQEEERHEQK--------HEQERREQRL--------KREQEERRDWLKREEETERHEQER 471
Query: 598 --------SDGEENIGWSTVNLDEEKQQQD 619
+ E W + +E ++QQ+
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQE 501
Score = 43.5 bits (101), Expect = 8e-04
Identities = 132/627 (21%), Positives = 242/627 (38%), Gaps = 73/627 (11%)
Query: 162 RQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLA---E 218
R+ E+ R+ + R Q L + ++ + W +R R +E+ L +
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 219 KRAKLLEEMDQEFGVSTLVEEEFGQRRQD----------LYSARDLQGLTVEHAIDSFRE 268
K AK + QE E E +RRQ+ L R+ Q L + FRE
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Query: 269 GETMILTLKDKG--VLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLA 326
E L +++G L+EE+ L +ER K + K+ L E E L
Sbjct: 1365 EE---LRHQEQGRKFLEEEQ------RLRRQERERKFL----KEEQQLRCQEREQ--QLR 1409
Query: 327 QQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRL 386
Q + R + + ER FR E+ RER+ E +LR + +L
Sbjct: 1410 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
Query: 387 ASEYLTPEEMVTFKKTKRR-----VKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRG 441
E EE ++ + R +++R++E++ R +L + + + +L
Sbjct: 1470 LQE---REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 442 RGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQK 501
+ R+R ++EE++ Q R ++ D EE Q L E + + +
Sbjct: 1527 QQRQR-KFLQEEQQLRRQ--ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583
Query: 502 QLEKGRRLRQ----LQQLQQL-RDSGEKVVEIVKKLESRQRGWEEDED--PERKGAIVFN 554
+ +K RR Q ++ QQL R G++ + + R R + EDE ER+ +
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLR-----QERDRKFREDEQLLQEREEQQLHR 1638
Query: 555 ATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEE---NIGWSTVNL 611
+ + L E P R+E+E+ + +RD + +GEE
Sbjct: 1639 QERD-RKFLEEEPQL----RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF 1693
Query: 612 DEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSA 671
EE+QQ L EE + R + + ET +++ R + K L
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL--- 1750
Query: 672 VYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYV--DETGRKLTPKEAFRQL 729
E++ ++ ++ + + F+E++ + + + + + E+ RK +E RQ
Sbjct: 1751 ----EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 730 SHRFH---GKGSGKMKTERRMKKLDEE 753
+ GK + E +L+E+
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQ 1833
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 61.6 bits (148), Expect = 3e-09
Identities = 113/529 (21%), Positives = 205/529 (38%), Gaps = 81/529 (15%)
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GE + RR AE EA + ER A+ + + E+ E A ++ + A+
Sbjct: 2081 GEAEAARRAAE-EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2139
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAK----- 175
+E + A+ E A++++ E LRQ+ ++ ++L +
Sbjct: 2140 KEAEQEAARRA--QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2197
Query: 176 ---EKRLLNQKLGKIKTLGED--------DPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+K LL+++L ++K + + L +E +L K + AE RA +L
Sbjct: 2198 TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL-KARIEAENRALIL 2256
Query: 225 EEMD-------QEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK 277
+ D +E V EE + A L+ L E E M LK
Sbjct: 2257 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM---LK 2313
Query: 278 DK-GVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSK 336
+K +QE + L+ +++ + R+ + D +++ LA++
Sbjct: 2314 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED-----KEQMAQQLAEET-----QG 2363
Query: 337 YDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEM 396
+ LE ER +LE A+ L+ R E RA+ R + E+
Sbjct: 2364 FQRTLEAERQR--QLEMSAEAERLKLRVAEMSRAQARAE------------------EDA 2403
Query: 397 VTFKKTKRRV-KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKE 455
F+K + +K+ + E + + L Q Q D + R R ++E+E EKE
Sbjct: 2404 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE---RLREAIAELEREKE 2460
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ--------------VLEEDEAELE--L 499
+ Q + E M +E+ Q +E+++A+LE
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 500 QKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
Q ++ K ++LR+ QQ QQ + E+ + E+R+R E +E RK
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2569
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/607 (22%), Positives = 237/607 (39%), Gaps = 101/607 (16%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
+ EA ++T R+ +AE ++ R + E AS + ++ S S + +L A+
Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEV------LLASKARAEEESRSTSEKSKQRLEAEA 1793
Query: 131 G-LKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE----LREKLAAAKEKRLLNQKLG 185
G + L A + A +E + A RQR E L EKLAA E
Sbjct: 1794 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT------- 1846
Query: 186 KIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
++KT E + L + A ER R+L +++ +R LEE + +EE Q R
Sbjct: 1847 RLKT--EAEIALKEKEAENERLRRLAEDEAFQRRR---LEEQAAQHKAD--IEERLAQLR 1899
Query: 246 QDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVE 305
+ S + Q VE + R+ E IL LK + +AE +E
Sbjct: 1900 KASDSELERQKGLVEDTLRQRRQVEEEILALK------------ASFEKAAAGKAELELE 1947
Query: 306 LRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLREREL 365
L + + + AED ++ SK ELE R E+ R RE
Sbjct: 1948 LGRIRSN----AED------------TLRSKEQAELEAARQRQLAAEEER-----RRREA 1986
Query: 366 EEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLP 425
EE R+Q +SL+ EE+ K +++R++ ++ R L
Sbjct: 1987 EE-----RVQ-KSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 426 LGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPG 485
Q RL+ + V+++++ + Q L + + ++ + E A
Sbjct: 2041 EAAQ-------KRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEA 2093
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQLQ-QLRDSGEKVVEIVKK---LESRQRGWEE 541
++ + + ++Q+E+ RL+Q + Q Q R + E ++K E+ +R E
Sbjct: 2094 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2153
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGE 601
+K A +A E + E L + ++EL E E+D +
Sbjct: 2154 QAALRQKQAA--DAEMEKHKKFAE---QTLRQKAQVEQELTTLRLQLE-------ETDHQ 2201
Query: 602 ENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARV 661
+N+ LDEE Q+ A +T + V L + + + L+ AR+
Sbjct: 2202 KNL------LDEELQR--LKAEATEAARQRSQVEEELFSVRVQMEELSKLK------ARI 2247
Query: 662 KAPNKSL 668
+A N++L
Sbjct: 2248 EAENRAL 2254
Score = 41.2 bits (95), Expect = 0.004
Identities = 133/654 (20%), Positives = 242/654 (37%), Gaps = 112/654 (17%)
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKE----KDLAEKRAKLLEEMDQE 230
+E+RL Q+ E+ L + A +E+ RQL + K AE+ AK L++ QE
Sbjct: 1346 EEERLAEQQRA------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1399
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK-------DKGVLQ 283
V RR++ Q +++ + R+ + K ++ L+
Sbjct: 1400 EVV----------RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLR 1449
Query: 284 EEEDV-LVNVNLVDKERAEKNVE-----LRKKKPD---YLPYAEDES------VDDLAQQ 328
EE++ +V + L ER E LR + + A++E+ V D +Q+
Sbjct: 1450 IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR 1509
Query: 329 KPRS---ILSKYDEELEGERP--------HSFRLEQGGTADGLRERELEEIRAKLRLQAQ 377
K ++ + S+ E E R RL+ LR+ E+E R Q Q
Sbjct: 1510 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERAR-----QVQ 1564
Query: 378 SLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGS 437
R A L + +KT + + ++++ V ++ Q + +
Sbjct: 1565 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE--- 1621
Query: 438 RLRGRGRRRVSE----------VEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
R R R + + + E V Q E E E
Sbjct: 1622 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1681
Query: 488 QVLEEDEA---ELELQKQLEKG---RRLRQLQQLQQLR---DSGEKVVEIVKKLESRQRG 538
Q + + E ELE Q+QL +G +RL Q+L +LR + GE+ +++++ +R +
Sbjct: 1682 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR 1741
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER-SANGGSE 597
+R+ +E + E+ + R E+E E+ ++R A G
Sbjct: 1742 EAAAATQKRQ-----ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 598 SDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQK 657
+ E +E K+Q+ + +E+ R A +L +K
Sbjct: 1797 RELAEEAARLRALAEEAKRQRQ-------LAEEDAARQRAEAERVL-----------AEK 1838
Query: 658 VARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETG 717
+A + + A +++K A +++ R E F + E+ + IE
Sbjct: 1839 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1898
Query: 718 RKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVAL 771
RK + E RQ KG + T R+ ++++EE L K S G L
Sbjct: 1899 RKASDSELERQ-------KGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL 1944
Score = 30.8 bits (68), Expect = 5.2
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 36/221 (16%)
Query: 364 ELEEIRAKLRLQAQSLSTV-----GPRLASEYL------------TPEEMVTFKKTKRRV 406
+LE++R+ + + L T+ G + A E L P + + TK +
Sbjct: 1073 KLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASL 1132
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDG-----DFGSRLRGRGRRRVSEVEEEKEPVPQPL 461
KK+R +A+ P D +D + G RL+ R R EVE +E V Q L
Sbjct: 1133 KKLR-------AQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL 1185
Query: 462 PSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDS 521
+ D+ E Q+ E+ L L+ RR ++ Q L DS
Sbjct: 1186 ERWQAVLAQTDVRQRELEQL----GRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1241
Query: 522 ---GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEF 559
E++ + LE +R E+ E+ +R NA ++
Sbjct: 1242 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDY 1282
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 61.6 bits (148), Expect = 3e-09
Identities = 113/529 (21%), Positives = 205/529 (38%), Gaps = 81/529 (15%)
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GE + RR AE EA + ER A+ + + E+ E A ++ + A+
Sbjct: 2085 GEAEAARRAAE-EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2143
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAK----- 175
+E + A+ E A++++ E LRQ+ ++ ++L +
Sbjct: 2144 KEAEQEAARRA--QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2201
Query: 176 ---EKRLLNQKLGKIKTLGED--------DPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+K LL+++L ++K + + L +E +L K + AE RA +L
Sbjct: 2202 TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL-KARIEAENRALIL 2260
Query: 225 EEMD-------QEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK 277
+ D +E V EE + A L+ L E E M LK
Sbjct: 2261 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM---LK 2317
Query: 278 DK-GVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSK 336
+K +QE + L+ +++ + R+ + D +++ LA++
Sbjct: 2318 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED-----KEQMAQQLAEET-----QG 2367
Query: 337 YDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEM 396
+ LE ER +LE A+ L+ R E RA+ R + E+
Sbjct: 2368 FQRTLEAERQR--QLEMSAEAERLKLRVAEMSRAQARAE------------------EDA 2407
Query: 397 VTFKKTKRRV-KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKE 455
F+K + +K+ + E + + L Q Q D + R R ++E+E EKE
Sbjct: 2408 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE---RLREAIAELEREKE 2464
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ--------------VLEEDEAELE--L 499
+ Q + E M +E+ Q +E+++A+LE
Sbjct: 2465 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2524
Query: 500 QKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
Q ++ K ++LR+ QQ QQ + E+ + E+R+R E +E RK
Sbjct: 2525 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2573
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/607 (22%), Positives = 237/607 (39%), Gaps = 101/607 (16%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
+ EA ++T R+ +AE ++ R + E AS + ++ S S + +L A+
Sbjct: 1744 QREAAAATQKRQELEAELAKVRAEMEV------LLASKARAEEESRSTSEKSKQRLEAEA 1797
Query: 131 G-LKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE----LREKLAAAKEKRLLNQKLG 185
G + L A + A +E + A RQR E L EKLAA E
Sbjct: 1798 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT------- 1850
Query: 186 KIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
++KT E + L + A ER R+L +++ +R LEE + +EE Q R
Sbjct: 1851 RLKT--EAEIALKEKEAENERLRRLAEDEAFQRRR---LEEQAAQHKAD--IEERLAQLR 1903
Query: 246 QDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVE 305
+ S + Q VE + R+ E IL LK + +AE +E
Sbjct: 1904 KASDSELERQKGLVEDTLRQRRQVEEEILALK------------ASFEKAAAGKAELELE 1951
Query: 306 LRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLREREL 365
L + + + AED ++ SK ELE R E+ R RE
Sbjct: 1952 LGRIRSN----AED------------TLRSKEQAELEAARQRQLAAEEER-----RRREA 1990
Query: 366 EEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLP 425
EE R+Q +SL+ EE+ K +++R++ ++ R L
Sbjct: 1991 EE-----RVQ-KSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2044
Query: 426 LGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPG 485
Q RL+ + V+++++ + Q L + + ++ + E A
Sbjct: 2045 EAAQ-------KRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEA 2097
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQLQ-QLRDSGEKVVEIVKK---LESRQRGWEE 541
++ + + ++Q+E+ RL+Q + Q Q R + E ++K E+ +R E
Sbjct: 2098 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2157
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGE 601
+K A +A E + E L + ++EL E E+D +
Sbjct: 2158 QAALRQKQAA--DAEMEKHKKFAE---QTLRQKAQVEQELTTLRLQLE-------ETDHQ 2205
Query: 602 ENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARV 661
+N+ LDEE Q+ A +T + V L + + + L+ AR+
Sbjct: 2206 KNL------LDEELQR--LKAEATEAARQRSQVEEELFSVRVQMEELSKLK------ARI 2251
Query: 662 KAPNKSL 668
+A N++L
Sbjct: 2252 EAENRAL 2258
Score = 41.2 bits (95), Expect = 0.004
Identities = 133/654 (20%), Positives = 242/654 (37%), Gaps = 112/654 (17%)
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKE----KDLAEKRAKLLEEMDQE 230
+E+RL Q+ E+ L + A +E+ RQL + K AE+ AK L++ QE
Sbjct: 1350 EEERLAEQQRA------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1403
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK-------DKGVLQ 283
V RR++ Q +++ + R+ + K ++ L+
Sbjct: 1404 EVV----------RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLR 1453
Query: 284 EEEDV-LVNVNLVDKERAEKNVE-----LRKKKPD---YLPYAEDES------VDDLAQQ 328
EE++ +V + L ER E LR + + A++E+ V D +Q+
Sbjct: 1454 IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR 1513
Query: 329 KPRS---ILSKYDEELEGERP--------HSFRLEQGGTADGLRERELEEIRAKLRLQAQ 377
K ++ + S+ E E R RL+ LR+ E+E R Q Q
Sbjct: 1514 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERAR-----QVQ 1568
Query: 378 SLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGS 437
R A L + +KT + + ++++ V ++ Q + +
Sbjct: 1569 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE--- 1625
Query: 438 RLRGRGRRRVSE----------VEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
R R R + + + E V Q E E E
Sbjct: 1626 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1685
Query: 488 QVLEEDEA---ELELQKQLEKG---RRLRQLQQLQQLR---DSGEKVVEIVKKLESRQRG 538
Q + + E ELE Q+QL +G +RL Q+L +LR + GE+ +++++ +R +
Sbjct: 1686 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR 1745
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER-SANGGSE 597
+R+ +E + E+ + R E+E E+ ++R A G
Sbjct: 1746 EAAAATQKRQ-----ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1800
Query: 598 SDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQK 657
+ E +E K+Q+ + +E+ R A +L +K
Sbjct: 1801 RELAEEAARLRALAEEAKRQRQ-------LAEEDAARQRAEAERVL-----------AEK 1842
Query: 658 VARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETG 717
+A + + A +++K A +++ R E F + E+ + IE
Sbjct: 1843 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1902
Query: 718 RKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVAL 771
RK + E RQ KG + T R+ ++++EE L K S G L
Sbjct: 1903 RKASDSELERQ-------KGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL 1948
Score = 30.8 bits (68), Expect = 5.2
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 36/221 (16%)
Query: 364 ELEEIRAKLRLQAQSLSTV-----GPRLASEYL------------TPEEMVTFKKTKRRV 406
+LE++R+ + + L T+ G + A E L P + + TK +
Sbjct: 1077 KLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASL 1136
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDG-----DFGSRLRGRGRRRVSEVEEEKEPVPQPL 461
KK+R +A+ P D +D + G RL+ R R EVE +E V Q L
Sbjct: 1137 KKLR-------AQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL 1189
Query: 462 PSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDS 521
+ D+ E Q+ E+ L L+ RR ++ Q L DS
Sbjct: 1190 ERWQAVLAQTDVRQRELEQL----GRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1245
Query: 522 ---GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEF 559
E++ + LE +R E+ E+ +R NA ++
Sbjct: 1246 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDY 1286
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 61.6 bits (148), Expect = 3e-09
Identities = 113/529 (21%), Positives = 205/529 (38%), Gaps = 81/529 (15%)
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GE + RR AE EA + ER A+ + + E+ E A ++ + A+
Sbjct: 2081 GEAEAARRAAE-EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2139
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAK----- 175
+E + A+ E A++++ E LRQ+ ++ ++L +
Sbjct: 2140 KEAEQEAARRA--QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2197
Query: 176 ---EKRLLNQKLGKIKTLGED--------DPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+K LL+++L ++K + + L +E +L K + AE RA +L
Sbjct: 2198 TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL-KARIEAENRALIL 2256
Query: 225 EEMD-------QEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK 277
+ D +E V EE + A L+ L E E M LK
Sbjct: 2257 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM---LK 2313
Query: 278 DK-GVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSK 336
+K +QE + L+ +++ + R+ + D +++ LA++
Sbjct: 2314 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED-----KEQMAQQLAEET-----QG 2363
Query: 337 YDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEM 396
+ LE ER +LE A+ L+ R E RA+ R + E+
Sbjct: 2364 FQRTLEAERQR--QLEMSAEAERLKLRVAEMSRAQARAE------------------EDA 2403
Query: 397 VTFKKTKRRV-KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKE 455
F+K + +K+ + E + + L Q Q D + R R ++E+E EKE
Sbjct: 2404 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE---RLREAIAELEREKE 2460
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ--------------VLEEDEAELE--L 499
+ Q + E M +E+ Q +E+++A+LE
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 500 QKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
Q ++ K ++LR+ QQ QQ + E+ + E+R+R E +E RK
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2569
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/607 (22%), Positives = 237/607 (39%), Gaps = 101/607 (16%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
+ EA ++T R+ +AE ++ R + E AS + ++ S S + +L A+
Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEV------LLASKARAEEESRSTSEKSKQRLEAEA 1793
Query: 131 G-LKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE----LREKLAAAKEKRLLNQKLG 185
G + L A + A +E + A RQR E L EKLAA E
Sbjct: 1794 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT------- 1846
Query: 186 KIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
++KT E + L + A ER R+L +++ +R LEE + +EE Q R
Sbjct: 1847 RLKT--EAEIALKEKEAENERLRRLAEDEAFQRRR---LEEQAAQHKAD--IEERLAQLR 1899
Query: 246 QDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVE 305
+ S + Q VE + R+ E IL LK + +AE +E
Sbjct: 1900 KASDSELERQKGLVEDTLRQRRQVEEEILALK------------ASFEKAAAGKAELELE 1947
Query: 306 LRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLREREL 365
L + + + AED ++ SK ELE R E+ R RE
Sbjct: 1948 LGRIRSN----AED------------TLRSKEQAELEAARQRQLAAEEER-----RRREA 1986
Query: 366 EEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLP 425
EE R+Q +SL+ EE+ K +++R++ ++ R L
Sbjct: 1987 EE-----RVQ-KSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 426 LGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPG 485
Q RL+ + V+++++ + Q L + + ++ + E A
Sbjct: 2041 EAAQ-------KRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEA 2093
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQLQ-QLRDSGEKVVEIVKK---LESRQRGWEE 541
++ + + ++Q+E+ RL+Q + Q Q R + E ++K E+ +R E
Sbjct: 2094 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2153
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGE 601
+K A +A E + E L + ++EL E E+D +
Sbjct: 2154 QAALRQKQAA--DAEMEKHKKFAE---QTLRQKAQVEQELTTLRLQLE-------ETDHQ 2201
Query: 602 ENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARV 661
+N+ LDEE Q+ A +T + V L + + + L+ AR+
Sbjct: 2202 KNL------LDEELQR--LKAEATEAARQRSQVEEELFSVRVQMEELSKLK------ARI 2247
Query: 662 KAPNKSL 668
+A N++L
Sbjct: 2248 EAENRAL 2254
Score = 41.2 bits (95), Expect = 0.004
Identities = 133/654 (20%), Positives = 242/654 (37%), Gaps = 112/654 (17%)
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKE----KDLAEKRAKLLEEMDQE 230
+E+RL Q+ E+ L + A +E+ RQL + K AE+ AK L++ QE
Sbjct: 1346 EEERLAEQQRA------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1399
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK-------DKGVLQ 283
V RR++ Q +++ + R+ + K ++ L+
Sbjct: 1400 EVV----------RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLR 1449
Query: 284 EEEDV-LVNVNLVDKERAEKNVE-----LRKKKPD---YLPYAEDES------VDDLAQQ 328
EE++ +V + L ER E LR + + A++E+ V D +Q+
Sbjct: 1450 IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR 1509
Query: 329 KPRS---ILSKYDEELEGERP--------HSFRLEQGGTADGLRERELEEIRAKLRLQAQ 377
K ++ + S+ E E R RL+ LR+ E+E R Q Q
Sbjct: 1510 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERAR-----QVQ 1564
Query: 378 SLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGS 437
R A L + +KT + + ++++ V ++ Q + +
Sbjct: 1565 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE--- 1621
Query: 438 RLRGRGRRRVSE----------VEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
R R R + + + E V Q E E E
Sbjct: 1622 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1681
Query: 488 QVLEEDEA---ELELQKQLEKG---RRLRQLQQLQQLR---DSGEKVVEIVKKLESRQRG 538
Q + + E ELE Q+QL +G +RL Q+L +LR + GE+ +++++ +R +
Sbjct: 1682 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR 1741
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER-SANGGSE 597
+R+ +E + E+ + R E+E E+ ++R A G
Sbjct: 1742 EAAAATQKRQ-----ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 598 SDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQK 657
+ E +E K+Q+ + +E+ R A +L +K
Sbjct: 1797 RELAEEAARLRALAEEAKRQRQ-------LAEEDAARQRAEAERVL-----------AEK 1838
Query: 658 VARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETG 717
+A + + A +++K A +++ R E F + E+ + IE
Sbjct: 1839 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1898
Query: 718 RKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVAL 771
RK + E RQ KG + T R+ ++++EE L K S G L
Sbjct: 1899 RKASDSELERQ-------KGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL 1944
Score = 30.8 bits (68), Expect = 5.2
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 36/221 (16%)
Query: 364 ELEEIRAKLRLQAQSLSTV-----GPRLASEYL------------TPEEMVTFKKTKRRV 406
+LE++R+ + + L T+ G + A E L P + + TK +
Sbjct: 1073 KLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASL 1132
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDG-----DFGSRLRGRGRRRVSEVEEEKEPVPQPL 461
KK+R +A+ P D +D + G RL+ R R EVE +E V Q L
Sbjct: 1133 KKLR-------AQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL 1185
Query: 462 PSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDS 521
+ D+ E Q+ E+ L L+ RR ++ Q L DS
Sbjct: 1186 ERWQAVLAQTDVRQRELEQL----GRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1241
Query: 522 ---GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEF 559
E++ + LE +R E+ E+ +R NA ++
Sbjct: 1242 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDY 1282
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 61.6 bits (148), Expect = 3e-09
Identities = 113/529 (21%), Positives = 205/529 (38%), Gaps = 81/529 (15%)
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GE + RR AE EA + ER A+ + + E+ E A ++ + A+
Sbjct: 2049 GEAEAARRAAE-EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2107
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAK----- 175
+E + A+ E A++++ E LRQ+ ++ ++L +
Sbjct: 2108 KEAEQEAARRA--QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2165
Query: 176 ---EKRLLNQKLGKIKTLGED--------DPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+K LL+++L ++K + + L +E +L K + AE RA +L
Sbjct: 2166 TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL-KARIEAENRALIL 2224
Query: 225 EEMD-------QEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK 277
+ D +E V EE + A L+ L E E M LK
Sbjct: 2225 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM---LK 2281
Query: 278 DK-GVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSK 336
+K +QE + L+ +++ + R+ + D +++ LA++
Sbjct: 2282 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED-----KEQMAQQLAEET-----QG 2331
Query: 337 YDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEM 396
+ LE ER +LE A+ L+ R E RA+ R + E+
Sbjct: 2332 FQRTLEAERQR--QLEMSAEAERLKLRVAEMSRAQARAE------------------EDA 2371
Query: 397 VTFKKTKRRV-KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKE 455
F+K + +K+ + E + + L Q Q D + R R ++E+E EKE
Sbjct: 2372 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE---RLREAIAELEREKE 2428
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ--------------VLEEDEAELE--L 499
+ Q + E M +E+ Q +E+++A+LE
Sbjct: 2429 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2488
Query: 500 QKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
Q ++ K ++LR+ QQ QQ + E+ + E+R+R E +E RK
Sbjct: 2489 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2537
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/607 (22%), Positives = 237/607 (39%), Gaps = 101/607 (16%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
+ EA ++T R+ +AE ++ R + E AS + ++ S S + +L A+
Sbjct: 1708 QREAAAATQKRQELEAELAKVRAEMEV------LLASKARAEEESRSTSEKSKQRLEAEA 1761
Query: 131 G-LKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE----LREKLAAAKEKRLLNQKLG 185
G + L A + A +E + A RQR E L EKLAA E
Sbjct: 1762 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT------- 1814
Query: 186 KIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
++KT E + L + A ER R+L +++ +R LEE + +EE Q R
Sbjct: 1815 RLKT--EAEIALKEKEAENERLRRLAEDEAFQRRR---LEEQAAQHKAD--IEERLAQLR 1867
Query: 246 QDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVE 305
+ S + Q VE + R+ E IL LK + +AE +E
Sbjct: 1868 KASDSELERQKGLVEDTLRQRRQVEEEILALK------------ASFEKAAAGKAELELE 1915
Query: 306 LRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLREREL 365
L + + + AED ++ SK ELE R E+ R RE
Sbjct: 1916 LGRIRSN----AED------------TLRSKEQAELEAARQRQLAAEEER-----RRREA 1954
Query: 366 EEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLP 425
EE R+Q +SL+ EE+ K +++R++ ++ R L
Sbjct: 1955 EE-----RVQ-KSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2008
Query: 426 LGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPG 485
Q RL+ + V+++++ + Q L + + ++ + E A
Sbjct: 2009 EAAQ-------KRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEA 2061
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQLQ-QLRDSGEKVVEIVKK---LESRQRGWEE 541
++ + + ++Q+E+ RL+Q + Q Q R + E ++K E+ +R E
Sbjct: 2062 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2121
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGE 601
+K A +A E + E L + ++EL E E+D +
Sbjct: 2122 QAALRQKQAA--DAEMEKHKKFAE---QTLRQKAQVEQELTTLRLQLE-------ETDHQ 2169
Query: 602 ENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARV 661
+N+ LDEE Q+ A +T + V L + + + L+ AR+
Sbjct: 2170 KNL------LDEELQR--LKAEATEAARQRSQVEEELFSVRVQMEELSKLK------ARI 2215
Query: 662 KAPNKSL 668
+A N++L
Sbjct: 2216 EAENRAL 2222
Score = 41.2 bits (95), Expect = 0.004
Identities = 133/654 (20%), Positives = 242/654 (37%), Gaps = 112/654 (17%)
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKE----KDLAEKRAKLLEEMDQE 230
+E+RL Q+ E+ L + A +E+ RQL + K AE+ AK L++ QE
Sbjct: 1314 EEERLAEQQRA------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1367
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK-------DKGVLQ 283
V RR++ Q +++ + R+ + K ++ L+
Sbjct: 1368 EVV----------RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLR 1417
Query: 284 EEEDV-LVNVNLVDKERAEKNVE-----LRKKKPD---YLPYAEDES------VDDLAQQ 328
EE++ +V + L ER E LR + + A++E+ V D +Q+
Sbjct: 1418 IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR 1477
Query: 329 KPRS---ILSKYDEELEGERP--------HSFRLEQGGTADGLRERELEEIRAKLRLQAQ 377
K ++ + S+ E E R RL+ LR+ E+E R Q Q
Sbjct: 1478 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERAR-----QVQ 1532
Query: 378 SLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGS 437
R A L + +KT + + ++++ V ++ Q + +
Sbjct: 1533 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE--- 1589
Query: 438 RLRGRGRRRVSE----------VEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
R R R + + + E V Q E E E
Sbjct: 1590 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1649
Query: 488 QVLEEDEA---ELELQKQLEKG---RRLRQLQQLQQLR---DSGEKVVEIVKKLESRQRG 538
Q + + E ELE Q+QL +G +RL Q+L +LR + GE+ +++++ +R +
Sbjct: 1650 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR 1709
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER-SANGGSE 597
+R+ +E + E+ + R E+E E+ ++R A G
Sbjct: 1710 EAAAATQKRQ-----ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1764
Query: 598 SDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQK 657
+ E +E K+Q+ + +E+ R A +L +K
Sbjct: 1765 RELAEEAARLRALAEEAKRQRQ-------LAEEDAARQRAEAERVL-----------AEK 1806
Query: 658 VARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETG 717
+A + + A +++K A +++ R E F + E+ + IE
Sbjct: 1807 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1866
Query: 718 RKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVAL 771
RK + E RQ KG + T R+ ++++EE L K S G L
Sbjct: 1867 RKASDSELERQ-------KGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL 1912
Score = 30.8 bits (68), Expect = 5.2
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 36/221 (16%)
Query: 364 ELEEIRAKLRLQAQSLSTV-----GPRLASEYL------------TPEEMVTFKKTKRRV 406
+LE++R+ + + L T+ G + A E L P + + TK +
Sbjct: 1041 KLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASL 1100
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDG-----DFGSRLRGRGRRRVSEVEEEKEPVPQPL 461
KK+R +A+ P D +D + G RL+ R R EVE +E V Q L
Sbjct: 1101 KKLR-------AQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL 1153
Query: 462 PSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDS 521
+ D+ E Q+ E+ L L+ RR ++ Q L DS
Sbjct: 1154 ERWQAVLAQTDVRQRELEQL----GRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1209
Query: 522 ---GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEF 559
E++ + LE +R E+ E+ +R NA ++
Sbjct: 1210 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDY 1250
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 61.6 bits (148), Expect = 3e-09
Identities = 113/529 (21%), Positives = 205/529 (38%), Gaps = 81/529 (15%)
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GE + RR AE EA + ER A+ + + E+ E A ++ + A+
Sbjct: 2218 GEAEAARRAAE-EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2276
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAK----- 175
+E + A+ E A++++ E LRQ+ ++ ++L +
Sbjct: 2277 KEAEQEAARRA--QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2334
Query: 176 ---EKRLLNQKLGKIKTLGED--------DPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+K LL+++L ++K + + L +E +L K + AE RA +L
Sbjct: 2335 TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL-KARIEAENRALIL 2393
Query: 225 EEMD-------QEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK 277
+ D +E V EE + A L+ L E E M LK
Sbjct: 2394 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM---LK 2450
Query: 278 DK-GVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSK 336
+K +QE + L+ +++ + R+ + D +++ LA++
Sbjct: 2451 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED-----KEQMAQQLAEET-----QG 2500
Query: 337 YDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEM 396
+ LE ER +LE A+ L+ R E RA+ R + E+
Sbjct: 2501 FQRTLEAERQR--QLEMSAEAERLKLRVAEMSRAQARAE------------------EDA 2540
Query: 397 VTFKKTKRRV-KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKE 455
F+K + +K+ + E + + L Q Q D + R R ++E+E EKE
Sbjct: 2541 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE---RLREAIAELEREKE 2597
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ--------------VLEEDEAELE--L 499
+ Q + E M +E+ Q +E+++A+LE
Sbjct: 2598 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2657
Query: 500 QKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
Q ++ K ++LR+ QQ QQ + E+ + E+R+R E +E RK
Sbjct: 2658 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2706
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/607 (22%), Positives = 237/607 (39%), Gaps = 101/607 (16%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
+ EA ++T R+ +AE ++ R + E AS + ++ S S + +L A+
Sbjct: 1877 QREAAAATQKRQELEAELAKVRAEMEV------LLASKARAEEESRSTSEKSKQRLEAEA 1930
Query: 131 G-LKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE----LREKLAAAKEKRLLNQKLG 185
G + L A + A +E + A RQR E L EKLAA E
Sbjct: 1931 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT------- 1983
Query: 186 KIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
++KT E + L + A ER R+L +++ +R LEE + +EE Q R
Sbjct: 1984 RLKT--EAEIALKEKEAENERLRRLAEDEAFQRRR---LEEQAAQHKAD--IEERLAQLR 2036
Query: 246 QDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVE 305
+ S + Q VE + R+ E IL LK + +AE +E
Sbjct: 2037 KASDSELERQKGLVEDTLRQRRQVEEEILALK------------ASFEKAAAGKAELELE 2084
Query: 306 LRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLREREL 365
L + + + AED ++ SK ELE R E+ R RE
Sbjct: 2085 LGRIRSN----AED------------TLRSKEQAELEAARQRQLAAEEER-----RRREA 2123
Query: 366 EEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLP 425
EE R+Q +SL+ EE+ K +++R++ ++ R L
Sbjct: 2124 EE-----RVQ-KSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2177
Query: 426 LGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPG 485
Q RL+ + V+++++ + Q L + + ++ + E A
Sbjct: 2178 EAAQ-------KRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEA 2230
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQLQ-QLRDSGEKVVEIVKK---LESRQRGWEE 541
++ + + ++Q+E+ RL+Q + Q Q R + E ++K E+ +R E
Sbjct: 2231 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2290
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGE 601
+K A +A E + E L + ++EL E E+D +
Sbjct: 2291 QAALRQKQAA--DAEMEKHKKFAE---QTLRQKAQVEQELTTLRLQLE-------ETDHQ 2338
Query: 602 ENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARV 661
+N+ LDEE Q+ A +T + V L + + + L+ AR+
Sbjct: 2339 KNL------LDEELQR--LKAEATEAARQRSQVEEELFSVRVQMEELSKLK------ARI 2384
Query: 662 KAPNKSL 668
+A N++L
Sbjct: 2385 EAENRAL 2391
Score = 41.2 bits (95), Expect = 0.004
Identities = 133/654 (20%), Positives = 242/654 (37%), Gaps = 112/654 (17%)
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKE----KDLAEKRAKLLEEMDQE 230
+E+RL Q+ E+ L + A +E+ RQL + K AE+ AK L++ QE
Sbjct: 1483 EEERLAEQQRA------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1536
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK-------DKGVLQ 283
V RR++ Q +++ + R+ + K ++ L+
Sbjct: 1537 EVV----------RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLR 1586
Query: 284 EEEDV-LVNVNLVDKERAEKNVE-----LRKKKPD---YLPYAEDES------VDDLAQQ 328
EE++ +V + L ER E LR + + A++E+ V D +Q+
Sbjct: 1587 IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR 1646
Query: 329 KPRS---ILSKYDEELEGERP--------HSFRLEQGGTADGLRERELEEIRAKLRLQAQ 377
K ++ + S+ E E R RL+ LR+ E+E R Q Q
Sbjct: 1647 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERAR-----QVQ 1701
Query: 378 SLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGS 437
R A L + +KT + + ++++ V ++ Q + +
Sbjct: 1702 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE--- 1758
Query: 438 RLRGRGRRRVSE----------VEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
R R R + + + E V Q E E E
Sbjct: 1759 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1818
Query: 488 QVLEEDEA---ELELQKQLEKG---RRLRQLQQLQQLR---DSGEKVVEIVKKLESRQRG 538
Q + + E ELE Q+QL +G +RL Q+L +LR + GE+ +++++ +R +
Sbjct: 1819 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR 1878
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER-SANGGSE 597
+R+ +E + E+ + R E+E E+ ++R A G
Sbjct: 1879 EAAAATQKRQ-----ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1933
Query: 598 SDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQK 657
+ E +E K+Q+ + +E+ R A +L +K
Sbjct: 1934 RELAEEAARLRALAEEAKRQRQ-------LAEEDAARQRAEAERVL-----------AEK 1975
Query: 658 VARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETG 717
+A + + A +++K A +++ R E F + E+ + IE
Sbjct: 1976 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 2035
Query: 718 RKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVAL 771
RK + E RQ KG + T R+ ++++EE L K S G L
Sbjct: 2036 RKASDSELERQ-------KGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL 2081
Score = 30.8 bits (68), Expect = 5.2
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 36/221 (16%)
Query: 364 ELEEIRAKLRLQAQSLSTV-----GPRLASEYL------------TPEEMVTFKKTKRRV 406
+LE++R+ + + L T+ G + A E L P + + TK +
Sbjct: 1210 KLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASL 1269
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDG-----DFGSRLRGRGRRRVSEVEEEKEPVPQPL 461
KK+R +A+ P D +D + G RL+ R R EVE +E V Q L
Sbjct: 1270 KKLR-------AQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL 1322
Query: 462 PSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDS 521
+ D+ E Q+ E+ L L+ RR ++ Q L DS
Sbjct: 1323 ERWQAVLAQTDVRQRELEQL----GRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1378
Query: 522 ---GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEF 559
E++ + LE +R E+ E+ +R NA ++
Sbjct: 1379 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDY 1419
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 61.6 bits (148), Expect = 3e-09
Identities = 113/529 (21%), Positives = 205/529 (38%), Gaps = 81/529 (15%)
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GE + RR AE EA + ER A+ + + E+ E A ++ + A+
Sbjct: 2059 GEAEAARRAAE-EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2117
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAK----- 175
+E + A+ E A++++ E LRQ+ ++ ++L +
Sbjct: 2118 KEAEQEAARRA--QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2175
Query: 176 ---EKRLLNQKLGKIKTLGED--------DPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+K LL+++L ++K + + L +E +L K + AE RA +L
Sbjct: 2176 TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL-KARIEAENRALIL 2234
Query: 225 EEMD-------QEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK 277
+ D +E V EE + A L+ L E E M LK
Sbjct: 2235 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM---LK 2291
Query: 278 DK-GVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSK 336
+K +QE + L+ +++ + R+ + D +++ LA++
Sbjct: 2292 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED-----KEQMAQQLAEET-----QG 2341
Query: 337 YDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEM 396
+ LE ER +LE A+ L+ R E RA+ R + E+
Sbjct: 2342 FQRTLEAERQR--QLEMSAEAERLKLRVAEMSRAQARAE------------------EDA 2381
Query: 397 VTFKKTKRRV-KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKE 455
F+K + +K+ + E + + L Q Q D + R R ++E+E EKE
Sbjct: 2382 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE---RLREAIAELEREKE 2438
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ--------------VLEEDEAELE--L 499
+ Q + E M +E+ Q +E+++A+LE
Sbjct: 2439 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2498
Query: 500 QKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
Q ++ K ++LR+ QQ QQ + E+ + E+R+R E +E RK
Sbjct: 2499 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2547
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/607 (22%), Positives = 237/607 (39%), Gaps = 101/607 (16%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
+ EA ++T R+ +AE ++ R + E AS + ++ S S + +L A+
Sbjct: 1718 QREAAAATQKRQELEAELAKVRAEMEV------LLASKARAEEESRSTSEKSKQRLEAEA 1771
Query: 131 G-LKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE----LREKLAAAKEKRLLNQKLG 185
G + L A + A +E + A RQR E L EKLAA E
Sbjct: 1772 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT------- 1824
Query: 186 KIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
++KT E + L + A ER R+L +++ +R LEE + +EE Q R
Sbjct: 1825 RLKT--EAEIALKEKEAENERLRRLAEDEAFQRRR---LEEQAAQHKAD--IEERLAQLR 1877
Query: 246 QDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVE 305
+ S + Q VE + R+ E IL LK + +AE +E
Sbjct: 1878 KASDSELERQKGLVEDTLRQRRQVEEEILALK------------ASFEKAAAGKAELELE 1925
Query: 306 LRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLREREL 365
L + + + AED ++ SK ELE R E+ R RE
Sbjct: 1926 LGRIRSN----AED------------TLRSKEQAELEAARQRQLAAEEER-----RRREA 1964
Query: 366 EEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLP 425
EE R+Q +SL+ EE+ K +++R++ ++ R L
Sbjct: 1965 EE-----RVQ-KSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2018
Query: 426 LGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPG 485
Q RL+ + V+++++ + Q L + + ++ + E A
Sbjct: 2019 EAAQ-------KRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEA 2071
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQLQ-QLRDSGEKVVEIVKK---LESRQRGWEE 541
++ + + ++Q+E+ RL+Q + Q Q R + E ++K E+ +R E
Sbjct: 2072 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2131
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGE 601
+K A +A E + E L + ++EL E E+D +
Sbjct: 2132 QAALRQKQAA--DAEMEKHKKFAE---QTLRQKAQVEQELTTLRLQLE-------ETDHQ 2179
Query: 602 ENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARV 661
+N+ LDEE Q+ A +T + V L + + + L+ AR+
Sbjct: 2180 KNL------LDEELQR--LKAEATEAARQRSQVEEELFSVRVQMEELSKLK------ARI 2225
Query: 662 KAPNKSL 668
+A N++L
Sbjct: 2226 EAENRAL 2232
Score = 41.2 bits (95), Expect = 0.004
Identities = 133/654 (20%), Positives = 242/654 (37%), Gaps = 112/654 (17%)
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKE----KDLAEKRAKLLEEMDQE 230
+E+RL Q+ E+ L + A +E+ RQL + K AE+ AK L++ QE
Sbjct: 1324 EEERLAEQQRA------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1377
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK-------DKGVLQ 283
V RR++ Q +++ + R+ + K ++ L+
Sbjct: 1378 EVV----------RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLR 1427
Query: 284 EEEDV-LVNVNLVDKERAEKNVE-----LRKKKPD---YLPYAEDES------VDDLAQQ 328
EE++ +V + L ER E LR + + A++E+ V D +Q+
Sbjct: 1428 IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR 1487
Query: 329 KPRS---ILSKYDEELEGERP--------HSFRLEQGGTADGLRERELEEIRAKLRLQAQ 377
K ++ + S+ E E R RL+ LR+ E+E R Q Q
Sbjct: 1488 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERAR-----QVQ 1542
Query: 378 SLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGS 437
R A L + +KT + + ++++ V ++ Q + +
Sbjct: 1543 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE--- 1599
Query: 438 RLRGRGRRRVSE----------VEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
R R R + + + E V Q E E E
Sbjct: 1600 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1659
Query: 488 QVLEEDEA---ELELQKQLEKG---RRLRQLQQLQQLR---DSGEKVVEIVKKLESRQRG 538
Q + + E ELE Q+QL +G +RL Q+L +LR + GE+ +++++ +R +
Sbjct: 1660 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR 1719
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER-SANGGSE 597
+R+ +E + E+ + R E+E E+ ++R A G
Sbjct: 1720 EAAAATQKRQ-----ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1774
Query: 598 SDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQK 657
+ E +E K+Q+ + +E+ R A +L +K
Sbjct: 1775 RELAEEAARLRALAEEAKRQRQ-------LAEEDAARQRAEAERVL-----------AEK 1816
Query: 658 VARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETG 717
+A + + A +++K A +++ R E F + E+ + IE
Sbjct: 1817 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1876
Query: 718 RKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVAL 771
RK + E RQ KG + T R+ ++++EE L K S G L
Sbjct: 1877 RKASDSELERQ-------KGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL 1922
Score = 30.8 bits (68), Expect = 5.2
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 36/221 (16%)
Query: 364 ELEEIRAKLRLQAQSLSTV-----GPRLASEYL------------TPEEMVTFKKTKRRV 406
+LE++R+ + + L T+ G + A E L P + + TK +
Sbjct: 1051 KLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASL 1110
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDG-----DFGSRLRGRGRRRVSEVEEEKEPVPQPL 461
KK+R +A+ P D +D + G RL+ R R EVE +E V Q L
Sbjct: 1111 KKLR-------AQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL 1163
Query: 462 PSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDS 521
+ D+ E Q+ E+ L L+ RR ++ Q L DS
Sbjct: 1164 ERWQAVLAQTDVRQRELEQL----GRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1219
Query: 522 ---GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEF 559
E++ + LE +R E+ E+ +R NA ++
Sbjct: 1220 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDY 1260
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 61.6 bits (148), Expect = 3e-09
Identities = 113/529 (21%), Positives = 205/529 (38%), Gaps = 81/529 (15%)
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GE + RR AE EA + ER A+ + + E+ E A ++ + A+
Sbjct: 2067 GEAEAARRAAE-EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2125
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAK----- 175
+E + A+ E A++++ E LRQ+ ++ ++L +
Sbjct: 2126 KEAEQEAARRA--QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2183
Query: 176 ---EKRLLNQKLGKIKTLGED--------DPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+K LL+++L ++K + + L +E +L K + AE RA +L
Sbjct: 2184 TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL-KARIEAENRALIL 2242
Query: 225 EEMD-------QEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK 277
+ D +E V EE + A L+ L E E M LK
Sbjct: 2243 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM---LK 2299
Query: 278 DK-GVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSK 336
+K +QE + L+ +++ + R+ + D +++ LA++
Sbjct: 2300 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED-----KEQMAQQLAEET-----QG 2349
Query: 337 YDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEM 396
+ LE ER +LE A+ L+ R E RA+ R + E+
Sbjct: 2350 FQRTLEAERQR--QLEMSAEAERLKLRVAEMSRAQARAE------------------EDA 2389
Query: 397 VTFKKTKRRV-KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKE 455
F+K + +K+ + E + + L Q Q D + R R ++E+E EKE
Sbjct: 2390 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE---RLREAIAELEREKE 2446
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ--------------VLEEDEAELE--L 499
+ Q + E M +E+ Q +E+++A+LE
Sbjct: 2447 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2506
Query: 500 QKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
Q ++ K ++LR+ QQ QQ + E+ + E+R+R E +E RK
Sbjct: 2507 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2555
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/607 (22%), Positives = 237/607 (39%), Gaps = 101/607 (16%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
+ EA ++T R+ +AE ++ R + E AS + ++ S S + +L A+
Sbjct: 1726 QREAAAATQKRQELEAELAKVRAEMEV------LLASKARAEEESRSTSEKSKQRLEAEA 1779
Query: 131 G-LKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE----LREKLAAAKEKRLLNQKLG 185
G + L A + A +E + A RQR E L EKLAA E
Sbjct: 1780 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT------- 1832
Query: 186 KIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
++KT E + L + A ER R+L +++ +R LEE + +EE Q R
Sbjct: 1833 RLKT--EAEIALKEKEAENERLRRLAEDEAFQRRR---LEEQAAQHKAD--IEERLAQLR 1885
Query: 246 QDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVE 305
+ S + Q VE + R+ E IL LK + +AE +E
Sbjct: 1886 KASDSELERQKGLVEDTLRQRRQVEEEILALK------------ASFEKAAAGKAELELE 1933
Query: 306 LRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLREREL 365
L + + + AED ++ SK ELE R E+ R RE
Sbjct: 1934 LGRIRSN----AED------------TLRSKEQAELEAARQRQLAAEEER-----RRREA 1972
Query: 366 EEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLP 425
EE R+Q +SL+ EE+ K +++R++ ++ R L
Sbjct: 1973 EE-----RVQ-KSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2026
Query: 426 LGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPG 485
Q RL+ + V+++++ + Q L + + ++ + E A
Sbjct: 2027 EAAQ-------KRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEA 2079
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQLQ-QLRDSGEKVVEIVKK---LESRQRGWEE 541
++ + + ++Q+E+ RL+Q + Q Q R + E ++K E+ +R E
Sbjct: 2080 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2139
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGE 601
+K A +A E + E L + ++EL E E+D +
Sbjct: 2140 QAALRQKQAA--DAEMEKHKKFAE---QTLRQKAQVEQELTTLRLQLE-------ETDHQ 2187
Query: 602 ENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARV 661
+N+ LDEE Q+ A +T + V L + + + L+ AR+
Sbjct: 2188 KNL------LDEELQR--LKAEATEAARQRSQVEEELFSVRVQMEELSKLK------ARI 2233
Query: 662 KAPNKSL 668
+A N++L
Sbjct: 2234 EAENRAL 2240
Score = 41.2 bits (95), Expect = 0.004
Identities = 133/654 (20%), Positives = 242/654 (37%), Gaps = 112/654 (17%)
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKE----KDLAEKRAKLLEEMDQE 230
+E+RL Q+ E+ L + A +E+ RQL + K AE+ AK L++ QE
Sbjct: 1332 EEERLAEQQRA------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1385
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK-------DKGVLQ 283
V RR++ Q +++ + R+ + K ++ L+
Sbjct: 1386 EVV----------RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLR 1435
Query: 284 EEEDV-LVNVNLVDKERAEKNVE-----LRKKKPD---YLPYAEDES------VDDLAQQ 328
EE++ +V + L ER E LR + + A++E+ V D +Q+
Sbjct: 1436 IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR 1495
Query: 329 KPRS---ILSKYDEELEGERP--------HSFRLEQGGTADGLRERELEEIRAKLRLQAQ 377
K ++ + S+ E E R RL+ LR+ E+E R Q Q
Sbjct: 1496 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERAR-----QVQ 1550
Query: 378 SLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGS 437
R A L + +KT + + ++++ V ++ Q + +
Sbjct: 1551 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE--- 1607
Query: 438 RLRGRGRRRVSE----------VEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
R R R + + + E V Q E E E
Sbjct: 1608 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1667
Query: 488 QVLEEDEA---ELELQKQLEKG---RRLRQLQQLQQLR---DSGEKVVEIVKKLESRQRG 538
Q + + E ELE Q+QL +G +RL Q+L +LR + GE+ +++++ +R +
Sbjct: 1668 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR 1727
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER-SANGGSE 597
+R+ +E + E+ + R E+E E+ ++R A G
Sbjct: 1728 EAAAATQKRQ-----ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1782
Query: 598 SDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQK 657
+ E +E K+Q+ + +E+ R A +L +K
Sbjct: 1783 RELAEEAARLRALAEEAKRQRQ-------LAEEDAARQRAEAERVL-----------AEK 1824
Query: 658 VARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETG 717
+A + + A +++K A +++ R E F + E+ + IE
Sbjct: 1825 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1884
Query: 718 RKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVAL 771
RK + E RQ KG + T R+ ++++EE L K S G L
Sbjct: 1885 RKASDSELERQ-------KGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL 1930
Score = 30.8 bits (68), Expect = 5.2
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 36/221 (16%)
Query: 364 ELEEIRAKLRLQAQSLSTV-----GPRLASEYL------------TPEEMVTFKKTKRRV 406
+LE++R+ + + L T+ G + A E L P + + TK +
Sbjct: 1059 KLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASL 1118
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDG-----DFGSRLRGRGRRRVSEVEEEKEPVPQPL 461
KK+R +A+ P D +D + G RL+ R R EVE +E V Q L
Sbjct: 1119 KKLR-------AQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL 1171
Query: 462 PSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDS 521
+ D+ E Q+ E+ L L+ RR ++ Q L DS
Sbjct: 1172 ERWQAVLAQTDVRQRELEQL----GRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1227
Query: 522 ---GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEF 559
E++ + LE +R E+ E+ +R NA ++
Sbjct: 1228 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDY 1268
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 61.6 bits (148), Expect = 3e-09
Identities = 113/529 (21%), Positives = 205/529 (38%), Gaps = 81/529 (15%)
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI 120
GE + RR AE EA + ER A+ + + E+ E A ++ + A+
Sbjct: 2108 GEAEAARRAAE-EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2166
Query: 121 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAK----- 175
+E + A+ E A++++ E LRQ+ ++ ++L +
Sbjct: 2167 KEAEQEAARRA--QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2224
Query: 176 ---EKRLLNQKLGKIKTLGED--------DPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+K LL+++L ++K + + L +E +L K + AE RA +L
Sbjct: 2225 TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL-KARIEAENRALIL 2283
Query: 225 EEMD-------QEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK 277
+ D +E V EE + A L+ L E E M LK
Sbjct: 2284 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM---LK 2340
Query: 278 DK-GVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSK 336
+K +QE + L+ +++ + R+ + D +++ LA++
Sbjct: 2341 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED-----KEQMAQQLAEET-----QG 2390
Query: 337 YDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEM 396
+ LE ER +LE A+ L+ R E RA+ R + E+
Sbjct: 2391 FQRTLEAERQR--QLEMSAEAERLKLRVAEMSRAQARAE------------------EDA 2430
Query: 397 VTFKKTKRRV-KKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKE 455
F+K + +K+ + E + + L Q Q D + R R ++E+E EKE
Sbjct: 2431 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE---RLREAIAELEREKE 2487
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ--------------VLEEDEAELE--L 499
+ Q + E M +E+ Q +E+++A+LE
Sbjct: 2488 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2547
Query: 500 QKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
Q ++ K ++LR+ QQ QQ + E+ + E+R+R E +E RK
Sbjct: 2548 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2596
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/607 (22%), Positives = 237/607 (39%), Gaps = 101/607 (16%)
Query: 71 EAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKL 130
+ EA ++T R+ +AE ++ R + E AS + ++ S S + +L A+
Sbjct: 1767 QREAAAATQKRQELEAELAKVRAEMEV------LLASKARAEEESRSTSEKSKQRLEAEA 1820
Query: 131 G-LKPLEVNAIKKEAGTKEEPVTADVINPMALRQREE----LREKLAAAKEKRLLNQKLG 185
G + L A + A +E + A RQR E L EKLAA E
Sbjct: 1821 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEAT------- 1873
Query: 186 KIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRR 245
++KT E + L + A ER R+L +++ +R LEE + +EE Q R
Sbjct: 1874 RLKT--EAEIALKEKEAENERLRRLAEDEAFQRRR---LEEQAAQHKAD--IEERLAQLR 1926
Query: 246 QDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVE 305
+ S + Q VE + R+ E IL LK + +AE +E
Sbjct: 1927 KASDSELERQKGLVEDTLRQRRQVEEEILALK------------ASFEKAAAGKAELELE 1974
Query: 306 LRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLREREL 365
L + + + AED ++ SK ELE R E+ R RE
Sbjct: 1975 LGRIRSN----AED------------TLRSKEQAELEAARQRQLAAEEER-----RRREA 2013
Query: 366 EEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLP 425
EE R+Q +SL+ EE+ K +++R++ ++ R L
Sbjct: 2014 EE-----RVQ-KSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2067
Query: 426 LGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPG 485
Q RL+ + V+++++ + Q L + + ++ + E A
Sbjct: 2068 EAAQ-------KRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEA 2120
Query: 486 SPQVLEEDEAELELQKQLEKGRRLRQLQQLQ-QLRDSGEKVVEIVKK---LESRQRGWEE 541
++ + + ++Q+E+ RL+Q + Q Q R + E ++K E+ +R E
Sbjct: 2121 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2180
Query: 542 DEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGE 601
+K A +A E + E L + ++EL E E+D +
Sbjct: 2181 QAALRQKQAA--DAEMEKHKKFAE---QTLRQKAQVEQELTTLRLQLE-------ETDHQ 2228
Query: 602 ENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARV 661
+N+ LDEE Q+ A +T + V L + + + L+ AR+
Sbjct: 2229 KNL------LDEELQR--LKAEATEAARQRSQVEEELFSVRVQMEELSKLK------ARI 2274
Query: 662 KAPNKSL 668
+A N++L
Sbjct: 2275 EAENRAL 2281
Score = 41.2 bits (95), Expect = 0.004
Identities = 133/654 (20%), Positives = 242/654 (37%), Gaps = 112/654 (17%)
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKE----KDLAEKRAKLLEEMDQE 230
+E+RL Q+ E+ L + A +E+ RQL + K AE+ AK L++ QE
Sbjct: 1373 EEERLAEQQRA------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1426
Query: 231 FGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLK-------DKGVLQ 283
V RR++ Q +++ + R+ + K ++ L+
Sbjct: 1427 EVV----------RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLR 1476
Query: 284 EEEDV-LVNVNLVDKERAEKNVE-----LRKKKPD---YLPYAEDES------VDDLAQQ 328
EE++ +V + L ER E LR + + A++E+ V D +Q+
Sbjct: 1477 IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQR 1536
Query: 329 KPRS---ILSKYDEELEGERP--------HSFRLEQGGTADGLRERELEEIRAKLRLQAQ 377
K ++ + S+ E E R RL+ LR+ E+E R Q Q
Sbjct: 1537 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERAR-----QVQ 1591
Query: 378 SLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGS 437
R A L + +KT + + ++++ V ++ Q + +
Sbjct: 1592 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE--- 1648
Query: 438 RLRGRGRRRVSE----------VEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSP 487
R R R + + + E V Q E E E
Sbjct: 1649 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1708
Query: 488 QVLEEDEA---ELELQKQLEKG---RRLRQLQQLQQLR---DSGEKVVEIVKKLESRQRG 538
Q + + E ELE Q+QL +G +RL Q+L +LR + GE+ +++++ +R +
Sbjct: 1709 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR 1768
Query: 539 WEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER-SANGGSE 597
+R+ +E + E+ + R E+E E+ ++R A G
Sbjct: 1769 EAAAATQKRQ-----ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1823
Query: 598 SDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQK 657
+ E +E K+Q+ + +E+ R A +L +K
Sbjct: 1824 RELAEEAARLRALAEEAKRQRQ-------LAEEDAARQRAEAERVL-----------AEK 1865
Query: 658 VARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETG 717
+A + + A +++K A +++ R E F + E+ + IE
Sbjct: 1866 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1925
Query: 718 RKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVAL 771
RK + E RQ KG + T R+ ++++EE L K S G L
Sbjct: 1926 RKASDSELERQ-------KGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL 1971
Score = 30.8 bits (68), Expect = 5.2
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 36/221 (16%)
Query: 364 ELEEIRAKLRLQAQSLSTV-----GPRLASEYL------------TPEEMVTFKKTKRRV 406
+LE++R+ + + L T+ G + A E L P + + TK +
Sbjct: 1100 KLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASL 1159
Query: 407 KKIRKKEKEVVVRADDLLPLGDQTQDG-----DFGSRLRGRGRRRVSEVEEEKEPVPQPL 461
KK+R +A+ P D +D + G RL+ R R EVE +E V Q L
Sbjct: 1160 KKLR-------AQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL 1212
Query: 462 PSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDS 521
+ D+ E Q+ E+ L L+ RR ++ Q L DS
Sbjct: 1213 ERWQAVLAQTDVRQRELEQL----GRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1268
Query: 522 ---GEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEF 559
E++ + LE +R E+ E+ +R NA ++
Sbjct: 1269 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDY 1309
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 59.7 bits (143), Expect = 1e-08
Identities = 153/743 (20%), Positives = 301/743 (40%), Gaps = 120/743 (16%)
Query: 87 EPSERRVK-REKRDDGYEAAASSKTS----SGDASSLSIEETNKL--------RAKLGLK 133
E SER++K E+ ++ SS S +A IE+ NK+ +KL
Sbjct: 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 134 PLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLA-AAKEKRLLNQKLGKIKTLGE 192
E IKKE +E + EEL +L KE LL +K+ +K E
Sbjct: 607 EFEKRQIKKELEHYKEKG----------ERAEELENELHHLEKENELLQKKITNLKITCE 656
Query: 193 DDPWLDDTAAWIER-SRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSA 251
L+ + +ER +R+L+K D + LE +++E ++ ++EE + R+++ S
Sbjct: 657 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE---NSQLDEENLELRRNVESL 713
Query: 252 R---------DLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKE--RA 300
+ L+ +E + ++G ++ K ++ E + V+ +D E R
Sbjct: 714 KCASMKMAQLQLENKELESEKEQLKKGLELL-----KASFKKTERLEVSYQGLDIENQRL 768
Query: 301 EKNVELRKKKPDYLPYA-EDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADG 359
+K +E KK L +D +++ QK L + LE + LEQ +
Sbjct: 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE 828
Query: 360 LRERELEEIRAKLRLQAQSLST--------VGPRLASEYLTPEEMVTFKKTKRRVKKIRK 411
+++LE+ +LR QA+ T +G +E+ +K++ R+K++ K
Sbjct: 829 KDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Query: 412 KEKEVVVRA----DDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTR 467
+ KE+V RA L+ L + ++ +++ E+ + L D+
Sbjct: 889 ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS 948
Query: 468 VENMDISDEEEGGAPPPGSPQVLEEDEAELE--LQKQLEKGRRLRQ--------LQQLQQ 517
++ E + + S ++ EE A LE L++ ++LRQ + L+Q
Sbjct: 949 TDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1008
Query: 518 LRDSGEKVVEIVKKLESRQRGWEEDE---------------DPERKGAIVFNATSEFCRT 562
+D E++V+ + WE + + ER A +
Sbjct: 1009 RQDE-ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQ 1067
Query: 563 LGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSA 622
L ++ T N Q +++ +R + S E+N T N + + ++
Sbjct: 1068 LKQLETQ----NNNLQAQILALQRQ--------TVSLQEQNTTLQTQNAKLQVENSTLNS 1115
Query: 623 SSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAID 682
ST+++++ A LL+ Q+ LE + V + + KSL ++ I+D ++
Sbjct: 1116 QSTSLMNQN--------AQLLIQQSS--LENENESVIKEREDLKSLYDSL--IKDHEKLE 1163
Query: 683 DKYSRR-EEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKM 741
+ R+ EY ++++E+ D R + QL K G++
Sbjct: 1164 LLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDR-------YNQLL-----KQKGQL 1211
Query: 742 KTERRMKKLDEEALLKKMSSSDT 764
+ +M K+++E +L + + +T
Sbjct: 1212 EDLEKMLKVEQEKMLLENKNHET 1234
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 59.3 bits (142), Expect = 1e-08
Identities = 159/755 (21%), Positives = 306/755 (40%), Gaps = 143/755 (18%)
Query: 87 EPSERRVK-REKRDDGYEAAASSKTS----SGDASSLSIEETNKL--------RAKLGLK 133
E SER++K E+ ++ SS S +A IE+ NK+ +KL
Sbjct: 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 134 PLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLA-AAKEKRLLNQKLGKIKTLGE 192
E IKKE +E + EEL +L KE LL +K+ +K E
Sbjct: 607 EFEKRQIKKELEHYKEKG----------ERAEELENELHHLEKENELLQKKITNLKITCE 656
Query: 193 DDPWLDDTAAWIER-SRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSA 251
L+ + +ER +R+L+K D + LE +++E ++ ++EE + R+++ S
Sbjct: 657 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE---NSQLDEENLELRRNVESL 713
Query: 252 R---------DLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKE--RA 300
+ L+ +E + ++G ++ K ++ E + V+ +D E R
Sbjct: 714 KCASMKMAQLQLENKELESEKEQLKKGLELL-----KASFKKTERLEVSYQGLDIENQRL 768
Query: 301 EKNVELRKKKPDYLPYA-EDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADG 359
+K +E KK L +D +++ QK L + LE + LEQ +
Sbjct: 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE 828
Query: 360 LRERELEEIRAKLRLQAQSLST--------VGPRLASEYLTPEEMVTFKKTKRRVKKIRK 411
+++LE+ +LR QA+ T +G +E+ +K++ R+K++ K
Sbjct: 829 KDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Query: 412 KEKEVVVRA-----------DDLL--PLGDQTQDGDFGS---RLRGRGRRRVSEVEEEKE 455
+ KE+V RA +DL+ L Q + D L G + + +E+
Sbjct: 889 ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS 948
Query: 456 PVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELE--LQKQLEKGRRLRQ-- 511
+DD+R + ++ E + S ++ EE A LE L++ ++LRQ
Sbjct: 949 -------TDDSRYKLLESKLE----STLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 997
Query: 512 ------LQQLQQLRDSGEKVVEIVKKLESRQRGWEEDE---------------DPERKGA 550
+ L+Q +D E++V+ + WE + + ER A
Sbjct: 998 KTVKKNYEALKQRQDE-ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNA 1056
Query: 551 IVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVN 610
+ L ++ T N Q +++ +R + S E+N T N
Sbjct: 1057 TLQAEKQALKTQLKQLETQ----NNNLQAQILALQRQ--------TVSLQEQNTTLQTQN 1104
Query: 611 LDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPS 670
+ + ++ ST+++++ A LL+ Q+ LE + V + + KSL
Sbjct: 1105 AKLQVENSTLNSQSTSLMNQN--------AQLLIQQSS--LENENESVIKEREDLKSLYD 1154
Query: 671 AVYCIEDKMAIDDKYSRR-EEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQL 729
++ I+D ++ + R+ EY ++++E+ D R + QL
Sbjct: 1155 SL--IKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDR-------YNQL 1205
Query: 730 SHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDT 764
K G+++ +M K+++E +L + + +T
Sbjct: 1206 L-----KQKGQLEDLEKMLKVEQEKMLLENKNHET 1235
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 58.2 bits (139), Expect = 3e-08
Identities = 108/453 (23%), Positives = 189/453 (41%), Gaps = 72/453 (15%)
Query: 207 SRQLQKEKDLAEK---RAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAI 263
S ++QK K A K + K +EE+ +E T VE+E + + L + +T E A+
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEE----TKVEDEKSEMEEALTA------ITEELAV 482
Query: 264 DSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVD 323
S +E + K++ EEE+V + V E E +K E+E
Sbjct: 483 -SMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEK--------EEEEGQ 533
Query: 324 DLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELE--EIRAKLRLQAQSLST 381
+ +++ S EE E+ S E+G +G E E E E AK + + S
Sbjct: 534 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS- 592
Query: 382 VGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRG 441
E T EE+V K ++ +K K V ++ P+ ++ + S +
Sbjct: 593 ------EEVATKEELVADAKVEKP-----EKAKSPVPKS----PVEEKGKSPVPKSPVEE 637
Query: 442 RGRRRV--SEVEEE-KEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELE 498
+G+ V S VEE+ K PVP+ + + EE+ +P P SP +EE +++ E
Sbjct: 638 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSP--VEEAKSKAE 695
Query: 499 LQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDED-PERKGA---IVFN 554
+ K +K + EK V+ K E ++ E+ +D PE+K A +
Sbjct: 696 VGKGEQK--------------EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 741
Query: 555 ATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDG---------EENIG 605
A +E + + +EE + L + E+ GGSE +G +E+I
Sbjct: 742 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIA 801
Query: 606 WSTVNLDEEKQQQDFSASSTTILDEEPIVNRGL 638
+ +E+ +Q+ + +E+ +V GL
Sbjct: 802 VNGEVEGKEEVEQETKEKGSGREEEKGVVTNGL 834
Score = 42.0 bits (97), Expect = 0.002
Identities = 145/784 (18%), Positives = 296/784 (37%), Gaps = 99/784 (12%)
Query: 31 RHREHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSE 90
R E + R GS SG R + RGS + + RS R A S
Sbjct: 16 RVTETRSSFSRVSGSPSSG------FRSQSWSRGSPSTVSSSYKRSMLAPR---LAYSSA 66
Query: 91 RRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKK----EAGT 146
E D ++++ SG + +N+ GL I+K E
Sbjct: 67 MLSSAESSLDFSQSSSLLNGGSGPGGDYKLSRSNEKEQLQGLNDRFAGYIEKVHYLEQQN 126
Query: 147 KEEPVTADVINPMALRQREELREKLAAAKEKRL---------LNQKLGKIKTLGEDDPWL 197
KE + A++ ALRQ++ +L A ++ + +N + +++ + D
Sbjct: 127 KE--IEAEI---QALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQL--DSDHLE 179
Query: 198 DDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYS-ARDLQG 256
+D ER + + +D E + L + +E ++LV+ E ++ Q L L+
Sbjct: 180 EDIHRLKERFEEEARLRDDTEAAIRALRKDIEE---ASLVKVELDKKVQSLQDEVAFLRS 236
Query: 257 LTVEHAIDSFREGETMILTLKDKGVLQEE-EDVLVNVNLVDKERAEKNVELRKK--KPDY 313
E D + + +T++ K L+ + L + + +++N+ ++ K Y
Sbjct: 237 NHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRY 296
Query: 314 LPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQ-GGTADGLRERELEEIRAKL 372
E + A + + +++Y +L+ + S LE GT + L ER+L +I +
Sbjct: 297 AKLTEAAEQNKEAIRSAKEEIAEYRRQLQSK---SIELESVRGTKESL-ERQLSDIEERH 352
Query: 373 RLQAQSLSTVGPRLASEYL-TPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQ 431
S +L +E T EM + + + + K ++ + A L G++T+
Sbjct: 353 NHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNV-KMALDIEIAAYRKLLEGEETR 411
Query: 432 DGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLE 491
F + G + + P+ +VE + + + +++E
Sbjct: 412 FSTFAGSITG-------PLYTHRPPITISSKIQKPKVEAPKLKVQHKF------VEEIIE 458
Query: 492 EDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAI 551
E + E E ++++ + + + + K E ++ E++E+PE +
Sbjct: 459 ETKVEDEKS-------------EMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 505
Query: 552 VFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNL 611
V S T E+ G +EE+E + E ++E + + +E G E G S
Sbjct: 506 VAAKKSPVKATAPEVKEE--EGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 563
Query: 612 DEEKQ---QQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAP---- 664
E+++ + + +E+ + + A + + + + V+K + K+P
Sbjct: 564 GEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA---TKEELVADAKVEKPEKAKSPVPKS 620
Query: 665 ------NKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGR 718
+P + + K + + + E+ G P V V+E +
Sbjct: 621 PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP-VSKSPVEEKAK 679
Query: 719 KLTPKEAFRQLSHRFH-GKGSGKMKTERRMKKLDEEALLKKMSS--SDTPLGTVALLQEK 775
PK + + GKG K + E+ +K+ +E ++K D P EK
Sbjct: 680 SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVP--------EK 731
Query: 776 QKAQ 779
+KA+
Sbjct: 732 KKAE 735
Score = 38.9 bits (89), Expect = 0.019
Identities = 68/321 (21%), Positives = 124/321 (38%), Gaps = 44/321 (13%)
Query: 5 KKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGERG 64
K+ GEKE G E+ K + GGS G ++ + GE
Sbjct: 521 KEEEGEKEEEE--------GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 572
Query: 65 SGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETN 124
+ G EAEA+ E+S+ ++ + + + + E A S S +EE
Sbjct: 573 AEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS------PVEEKG 626
Query: 125 KLRA------KLGLKPLEVNAI--KKEAGTKEEPVTADVINPMALRQREELREKLAAAK- 175
K + G P+ + + K ++ + PV +P++ EE + K K
Sbjct: 627 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEE-KAKSPVPKS 685
Query: 176 --EKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKR---AKLLEEMDQE 230
E+ ++GK + E++ + + + ++ +K KD+ EK+ + + EE E
Sbjct: 686 PVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAE 745
Query: 231 F-----GVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVL-QE 284
V +E+E + + L ++ + E S EG DKG
Sbjct: 746 VVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGG--SEEEG-------SDKGAKGSR 796
Query: 285 EEDVLVNVNLVDKERAEKNVE 305
+ED+ VN + KE E+ +
Sbjct: 797 KEDIAVNGEVEGKEEVEQETK 817
Score = 32.7 bits (73), Expect = 1.4
Identities = 64/303 (21%), Positives = 119/303 (39%), Gaps = 35/303 (11%)
Query: 2 GSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGS--GGSGGERRKRSRER 59
GSS+K GE+E T A A A + + E K + + + E+ ++++
Sbjct: 557 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 616
Query: 60 GGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLS 119
+ +G +S + +S P + EK + + S
Sbjct: 617 VPKSPVEEKGKSPVPKSPVEEKGKS---PVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP 673
Query: 120 IEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRL 179
+EE K ++ + P+E K E G E Q+EE +++ A ++
Sbjct: 674 VEE--KAKSPVPKSPVEEAKSKAEVGKGE--------------QKEEEEKEVKEAPKEEK 717
Query: 180 LNQKLGKIKTLGE----DDPWLDDTAA---WIERSRQLQKEKDLAEKRAKLLEEMDQEFG 232
+ +K K K + E + P ++ A I +S ++ EK+ E+ L +E ++E
Sbjct: 718 VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKA 777
Query: 233 VSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREG-ETMILTLKDKGVLQEEEDVLVN 291
EE G + S ++ + A++ EG E + K+KG +EEE +V
Sbjct: 778 GGEGGSEEEGSDKGAKGSRKE------DIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831
Query: 292 VNL 294
L
Sbjct: 832 NGL 834
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 58.2 bits (139), Expect = 3e-08
Identities = 108/453 (23%), Positives = 189/453 (41%), Gaps = 72/453 (15%)
Query: 207 SRQLQKEKDLAEK---RAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAI 263
S ++QK K A K + K +EE+ +E T VE+E + + L + +T E A+
Sbjct: 57 SSKIQKPKVEAPKLKVQHKFVEEIIEE----TKVEDEKSEMEEALTA------ITEELAV 106
Query: 264 DSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVD 323
S +E + K++ EEE+V + V E E +K E+E
Sbjct: 107 -SMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEK--------EEEEGQ 157
Query: 324 DLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELE--EIRAKLRLQAQSLST 381
+ +++ S EE E+ S E+G +G E E E E AK + + S
Sbjct: 158 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS- 216
Query: 382 VGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRG 441
E T EE+V K ++ +K K V ++ P+ ++ + S +
Sbjct: 217 ------EEVATKEELVADAKVEKP-----EKAKSPVPKS----PVEEKGKSPVPKSPVEE 261
Query: 442 RGRRRV--SEVEEE-KEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELE 498
+G+ V S VEE+ K PVP+ + + EE+ +P P SP +EE +++ E
Sbjct: 262 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSP--VEEAKSKAE 319
Query: 499 LQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDED-PERKGA---IVFN 554
+ K +K + EK V+ K E ++ E+ +D PE+K A +
Sbjct: 320 VGKGEQK--------------EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 365
Query: 555 ATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDG---------EENIG 605
A +E + + +EE + L + E+ GGSE +G +E+I
Sbjct: 366 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIA 425
Query: 606 WSTVNLDEEKQQQDFSASSTTILDEEPIVNRGL 638
+ +E+ +Q+ + +E+ +V GL
Sbjct: 426 VNGEVEGKEEVEQETKEKGSGREEEKGVVTNGL 458
Score = 38.9 bits (89), Expect = 0.019
Identities = 68/321 (21%), Positives = 124/321 (38%), Gaps = 44/321 (13%)
Query: 5 KKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGERG 64
K+ GEKE G E+ K + GGS G ++ + GE
Sbjct: 145 KEEEGEKEEEE--------GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 196
Query: 65 SGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETN 124
+ G EAEA+ E+S+ ++ + + + + E A S S +EE
Sbjct: 197 AEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS------PVEEKG 250
Query: 125 KLRA------KLGLKPLEVNAI--KKEAGTKEEPVTADVINPMALRQREELREKLAAAK- 175
K + G P+ + + K ++ + PV +P++ EE + K K
Sbjct: 251 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEE-KAKSPVPKS 309
Query: 176 --EKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKR---AKLLEEMDQE 230
E+ ++GK + E++ + + + ++ +K KD+ EK+ + + EE E
Sbjct: 310 PVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAE 369
Query: 231 F-----GVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVL-QE 284
V +E+E + + L ++ + E S EG DKG
Sbjct: 370 VVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGG--SEEEG-------SDKGAKGSR 420
Query: 285 EEDVLVNVNLVDKERAEKNVE 305
+ED+ VN + KE E+ +
Sbjct: 421 KEDIAVNGEVEGKEEVEQETK 441
Score = 35.8 bits (81), Expect = 0.16
Identities = 52/265 (19%), Positives = 103/265 (38%), Gaps = 30/265 (11%)
Query: 531 KLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEER 590
K E ++ E++E+PE + V S T E+ G +EE+E + E ++E
Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE--EGEKEEEEGQEEEEEEDEG 166
Query: 591 SANGGSESDGEENIGWSTVNLDEEKQ---QQDFSASSTTILDEEPIVNRGLAAALLLCQN 647
+ + +E G E G S E+++ + + +E+ + + A +
Sbjct: 167 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA---TKE 223
Query: 648 KGLLETTVQKVARVKAP----------NKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQD 697
+ + + V+K + K+P +P + + K + + +
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 283
Query: 698 FKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFH-GKGSGKMKTERRMKKLDEEALL 756
E+ G P V V+E + PK + + GKG K + E+ +K+ +E +
Sbjct: 284 PVEEKGKSP-VSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 342
Query: 757 KKMSS--SDTPLGTVALLQEKQKAQ 779
+K D P EK+KA+
Sbjct: 343 EKKEEKPKDVP--------EKKKAE 359
Score = 32.7 bits (73), Expect = 1.4
Identities = 64/303 (21%), Positives = 119/303 (39%), Gaps = 35/303 (11%)
Query: 2 GSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGS--GGSGGERRKRSRER 59
GSS+K GE+E T A A A + + E K + + + E+ ++++
Sbjct: 181 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 240
Query: 60 GGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLS 119
+ +G +S + +S P + EK + + S
Sbjct: 241 VPKSPVEEKGKSPVPKSPVEEKGKS---PVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP 297
Query: 120 IEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRL 179
+EE K ++ + P+E K E G E Q+EE +++ A ++
Sbjct: 298 VEE--KAKSPVPKSPVEEAKSKAEVGKGE--------------QKEEEEKEVKEAPKEEK 341
Query: 180 LNQKLGKIKTLGE----DDPWLDDTAA---WIERSRQLQKEKDLAEKRAKLLEEMDQEFG 232
+ +K K K + E + P ++ A I +S ++ EK+ E+ L +E ++E
Sbjct: 342 VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKA 401
Query: 233 VSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREG-ETMILTLKDKGVLQEEEDVLVN 291
EE G + S ++ + A++ EG E + K+KG +EEE +V
Sbjct: 402 GGEGGSEEEGSDKGAKGSRKE------DIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 455
Query: 292 VNL 294
L
Sbjct: 456 NGL 458
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 57.4 bits (137), Expect = 5e-08
Identities = 147/782 (18%), Positives = 288/782 (36%), Gaps = 128/782 (16%)
Query: 105 AASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPV--TADVINPMALR 162
++S+ ++ SSLS E+ L +L + +++E K E + T ++ + L
Sbjct: 231 SSSADSTPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEDKTEQLVDTRHEVDQLVLE 290
Query: 163 QREELREKLAAAKEKRL----------LNQKLGKIKTLGED------------------D 194
++ +E + A + R L +K +++ L + +
Sbjct: 291 LQKVKQENIQLAADARSARAYRDELDSLREKANRVERLELELTRCKEKLHDVDFYKARME 350
Query: 195 PWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDL 254
+D IE L+++ A R + E+++E + + DL RD
Sbjct: 351 ELREDNIILIETKAMLEEQLTAARARGDKVHELEKE-------NLQLKSKLHDLELDRDT 403
Query: 255 QGLTVEHAIDSFREGETMILTLKDKGVLQEE-------EDVLVNVNLVDKERAEKNVELR 307
+E ++ E M+L + K + E E + N +L D R EL
Sbjct: 404 DKKRIEELLE-----ENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELN 458
Query: 308 KKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEE 367
+ + E E+ ++G R S LE+ G G E+E +
Sbjct: 459 ECASSRILKLEKEN-------------QSLQSTIQGLRDASLVLEESGLKCGELEKENHQ 505
Query: 368 IRAKL-RLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPL 426
+ K+ +LQ Q L E + +++ T + R K+ + + E + +AD +
Sbjct: 506 LSKKIEKLQTQ--------LEREKQSNQDLETLSEELIREKEQLQSDMETL-KADKARQI 556
Query: 427 GDQTQDGDFGSR----LRGRGR----RRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEE 478
D Q+ D +R LR R + R+ +VE+E + + Q + + ++ ++ +
Sbjct: 557 KDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQL 616
Query: 479 GGAPPPGSPQVLEEDEAELELQK-QLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQR 537
+ ++ E ELQ+ Q E GR R++ L+ + E + + L+ R
Sbjct: 617 HRDLEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENR 676
Query: 538 GWEEDEDPERKGAIVF----------NATSEFCRTLGEIPTYGLAGNREEQEELMDFERD 587
+ D + ++ +A + R L E + + + E ER+
Sbjct: 677 TLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLERE 736
Query: 588 EERSANG-------GSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAA 640
+E G +S+ E + + +V+ + + QQ +SS E + A
Sbjct: 737 KEELRKNVDLLKALGKKSERLE-LSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAE 795
Query: 641 ALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKE 700
L ++ L ++ + K+L V +E DK +E + Q +
Sbjct: 796 RQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEK-----DKKLLEKEAKRLWQQVEL 850
Query: 701 KDGYKPD--VKIEYVDETGRKLTPKEAF---------------RQLSHRF--HGKGSGKM 741
KD D K+ V++ R L + A R L+ + H + +
Sbjct: 851 KDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDLTKQVTVHARTLTTL 910
Query: 742 KTERRMKKLDEEALLKKMSSSDTPLGTVAL-----LQEKQKAQKTPYIVLSGSGKSMNAN 796
+ + ++KL + L ++ L V L LQE T Y +L G +S
Sbjct: 911 REDLVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQEDDSGSDTKYKILEGRNESALKT 970
Query: 797 TI 798
T+
Sbjct: 971 TL 972
Score = 32.7 bits (73), Expect = 1.4
Identities = 56/275 (20%), Positives = 121/275 (44%), Gaps = 26/275 (9%)
Query: 155 VINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEK 214
V+ + +Q +KL+ EK LN++L L EDD D +E + +
Sbjct: 915 VLEKLKSQQLSSELDKLSQELEKVGLNREL----LLQEDDSGSDTKYKILEGRNESALKT 970
Query: 215 DLAEKRAKLL---EEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFRE--G 269
LA K K++ +M+++ ++ +E E +++ + R QG +H +SF+ G
Sbjct: 971 TLAMKEEKIVLLEAQMEEKASLNRQLESELQMLKKECETLRQNQG-EGQHLQNSFKHPAG 1029
Query: 270 ETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQK 329
+T + ++ + + V K+RA +EL + AE + + + Q
Sbjct: 1030 KTAASHQGKEAWGPGHKEATMELLRV-KDRA---IELERNNAAL--QAEKQLLKEQLQHL 1083
Query: 330 PRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASE 389
++ + L ++ +F E T L+ AKL+++ +LS+ L ++
Sbjct: 1084 ETQNVTFSSQILTLQKQSAFLQEHNTT--------LQTQTAKLQVENSTLSSQSAALTAQ 1135
Query: 390 YLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLL 424
Y + T K+T+ + ++++++++ + LL
Sbjct: 1136 YTLLQNHHTAKETEN--ESLQRQQEQLTAAYEALL 1168
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 57.0 bits (136), Expect = 7e-08
Identities = 160/722 (22%), Positives = 306/722 (42%), Gaps = 88/722 (12%)
Query: 67 RRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI-EETNK 125
++G E + + + Q +E KR+K D + +K S GD + + E+ +K
Sbjct: 1226 KQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL-HAKVSEGDRLRVELAEKASK 1284
Query: 126 LRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQ------REELREKLAAAKEKRL 179
L+ +L V+ + +EA K D + + Q +EE R+KL + R
Sbjct: 1285 LQNELD----NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
Query: 180 LNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEK-DLAEKRAKLLEEMDQEFGVSTLVE 238
L ++ ++ E++ E + L+K+ L + A +++D + G +E
Sbjct: 1341 LEEEKNSLQEQQEEEE---------EARKNLEKQVLALQSQLADTKKKVDDDLGTIESLE 1391
Query: 239 EEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKE 298
E +++ L A L E A+ ++ + E K K LQ+E D L V+L +
Sbjct: 1392 EA---KKKLLKDAEALSQRLEEKAL-AYDKLE------KTKNRLQQELDDLT-VDLDHQR 1440
Query: 299 RAEKNVELRKKKPDYLPYAEDESVDD-LAQQKPRSILSKYDEELEGERPHSFRLEQGGTA 357
+ N+E ++KK D L AE++S+ A+++ R+ ++E + + LE+ A
Sbjct: 1441 QVASNLEKKQKKFDQL-LAEEKSISARYAEERDRAEAEAREKETKA-LSLARALEEALEA 1498
Query: 358 DGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVV 417
ER+ +++RA + S VG + L + ++ + ++ + E E+
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDVGKNVHE--LEKSKRALEQQVEEMRTQLEELEDELQ 1556
Query: 418 VRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEE 477
D L L Q ++ + R + +E+ E + L +E ++ DE
Sbjct: 1557 ATEDAKLRLEVNMQ------AMKAQFERDLQTRDEQNEEKKRLLIKQVRELE-AELEDER 1609
Query: 478 EGGAPPPGSPQVLEEDEAELELQKQLEKGRR---LRQLQQLQ-QLRDSGEKVVEIVKKLE 533
+ A S + +E D +LE Q + R ++QL++LQ Q++D E+ +
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR---ELEEARA 1666
Query: 534 SRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQE--ELMDFERDEERS 591
SR + + ++ E+K + + +E + E+ + A EQE EL D + S
Sbjct: 1667 SRDEIFAQSKESEKK---LKSLEAEILQLQEELASSERARRHAEQERDELAD---EITNS 1720
Query: 592 ANGGSE-SDGEENIGWSTVNLDEEKQQQDFSAS-------STTILDEEPIVNRGLAAALL 643
A+G S D + + L+EE +++ + TT+ + +N LAA
Sbjct: 1721 ASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTL--QVDTLNAELAAERS 1778
Query: 644 LCQNKGLLETTVQKVAR-VKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKD 702
Q +++ + +KA + L AV K S E G ++ E++
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAV-----KSKFKATISALEAKIGQLEEQLEQE 1833
Query: 703 GYKPDVKIEYVDETGRKLTPKEAFRQL-SHRFHG--------KGSGKMK-TERRMKKLDE 752
+ + V T +KL KE F Q+ R H K + +MK +R++++ +E
Sbjct: 1834 AKERAAANKLVRRTEKKL--KEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEE 1891
Query: 753 EA 754
EA
Sbjct: 1892 EA 1893
Score = 54.3 bits (129), Expect = 4e-07
Identities = 110/586 (18%), Positives = 241/586 (41%), Gaps = 58/586 (9%)
Query: 211 QKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGE 270
++E++L K +LL+ +++ V +EE ++ Q L +++ ++ + F E E
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEE-MERKHQQLLEEKNILAEQLQAETELFAEAE 907
Query: 271 TMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAED--ESVDDLAQQ 328
M L K QE E++L ++ +E E+N L+ +K + +D E +D+
Sbjct: 908 EMRARLAAKK--QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 329 KPRSILSKYDEELEGER-PHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLA 387
+ + L K E + ++ L + + ++E++L E R ++ +LA
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR---------IAECSSQLA 1016
Query: 388 SEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRV 447
E ++ + + KIR K++ ++ ++ L ++T+ L R+
Sbjct: 1017 EE----------EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQ-----ELEKAKRKLD 1061
Query: 448 SEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGR 507
E + ++ + + D + +EE GA G + L ++ A L++ ++L+
Sbjct: 1062 GETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNA-LKVVRELQA-- 1118
Query: 508 RLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDP---ERKGAIVFNATSEFCRTLG 564
Q+ +L++ E K E ++R E+ + E + + A + RT
Sbjct: 1119 ------QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKR 1172
Query: 565 EIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWST-VNLDEEKQQQDFSAS 623
E L EE+ + + + + R + + + E + + + EK +Q
Sbjct: 1173 EQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETD 1232
Query: 624 STTILDEEPIVNRGLAAALLLCQNKGLLETTVQKV-ARVKAPNK---SLPSAVYCIEDKM 679
+ + E ++ + A + + L+ VQ++ A+V ++ L +++++
Sbjct: 1233 NKELACEVKVLQQVKAESE---HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1289
Query: 680 AIDDKYSRREEYRG--FTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKG 737
E +G F +D + D + +ET +KL RQL +
Sbjct: 1290 DNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQ 1349
Query: 738 SGKMKTERRMKKLDEEALLKKMSSSDT------PLGTVALLQEKQK 777
+ + E K L+++ L + +DT LGT+ L+E +K
Sbjct: 1350 EQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKK 1395
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 57.0 bits (136), Expect = 7e-08
Identities = 131/620 (21%), Positives = 218/620 (35%), Gaps = 102/620 (16%)
Query: 27 EQPPRHR----EHKKHKH-RSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGR 81
+ PPRHR E +H H R+ S ERR+ +R + R E E S+
Sbjct: 386 QSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRD 445
Query: 82 ERSQAEPSERRVKREKRD-----------------DGYEAAASSKTSSGDASSLSIEETN 124
R EP + R +R+ RD + + + +K S S S + +
Sbjct: 446 HRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAH 505
Query: 125 KLRAKLGLKPLEVNAIKKEAGT-------KEEPVTADVINPMALRQREELRE-------- 169
R + G E +EE ++ N R E+R
Sbjct: 506 DYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRG 565
Query: 170 KLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQ 229
++ EK + +I + + + D +W RS E+D +R + D
Sbjct: 566 RVPELPEKGSRGSRGSQIDSHSSNSNYHD---SWETRSSY--PERDRYPERDNRDQARDS 620
Query: 230 EFGVSTLVEEEFGQRRQDLYSARDL--QGLTVEHAIDSFREGETMILTLKDKGVLQEEED 287
F + R +D + + QG E D RE + D+ + + D
Sbjct: 621 SFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRV-----DR--VDDRRD 673
Query: 288 VLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPH 347
++ER + R+++ D E E + A+++ R + D E + +R H
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 348 SFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVK 407
D RERE E R K R + + EE ++ +R +
Sbjct: 734 ----------DRERERERERDREKERERER----------------EERERERERERERE 767
Query: 408 KIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTR 467
+ R++E+E D ++ + D+ + +GR RR E EE P D R
Sbjct: 768 RERERERERARERDK-----ERERQRDWEDKDKGRDDRR--EKREEIREDRNPRDGHDER 820
Query: 468 VENMDISDEEEGGAPPPGSPQVLEEDEAELEL----QKQLEKGRRLRQLQQLQQLRDSGE 523
EG P SP+ E + + + EK R L Q+ + Q+ R
Sbjct: 821 KSKKRY--RNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSP 878
Query: 524 KVVEIVKKLESRQRGW-EEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELM 582
+ E RQ W EED PERK + E + + + EQ E++
Sbjct: 879 SHL-----TEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSV------DKQREQTEIL 927
Query: 583 DFERDEERSANGGSESDGEE 602
+ R + G +S+ E
Sbjct: 928 ESSRMRAQDIIGHHQSEDRE 947
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 55.1 bits (131), Expect = 3e-07
Identities = 113/492 (22%), Positives = 209/492 (42%), Gaps = 71/492 (14%)
Query: 66 GRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNK 125
G RGA A A + +R + E + + +EK D + A + + +K
Sbjct: 907 GLRGALAAAEA-----KRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSK 961
Query: 126 LRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQRE------ELRE-----KLAAA 174
++ + +K L E EE V AD +A R+R+ EL++ KL A
Sbjct: 962 VQLEGKVKELS------ERLEDEEEVNAD----LAARRRKLEDECTELKKDIDDLKLTLA 1011
Query: 175 KEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQ------------LQKEKDLAEKRAK 222
K ++ K+K L E+ LD++ A + + ++ LQ E+D K
Sbjct: 1012 KAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTK 1071
Query: 223 LLEEMDQEF-GVSTLVEEEFGQRRQDLYSARDLQG---LTVEHAIDSFREGETMILTLKD 278
++Q+ + +E+E R + R L+G LT E D+ ++ + L++
Sbjct: 1072 AKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQ----QLEE 1127
Query: 279 KGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYD 338
K L++++ L ++L ++ +++KK + AE+ + A++ R+ + K
Sbjct: 1128 K--LKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQR 1185
Query: 339 EELEGERPH-SFRLEQGGTA-----DGLRERELEEIRAKLRLQAQSL---STVGPRLASE 389
E E S RLE+ G A +G R+RE E R + L+ +L +TV +
Sbjct: 1186 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 1245
Query: 390 YLTPEEMVTFKKTKRRVK-KIRKKEKEVVVRADDLLP-LGDQTQDGDFGSRLRGRGRRRV 447
E+ + +RV+ K+ K++ E+ + DDL + T+ +L ++
Sbjct: 1246 AEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQL 1305
Query: 448 SEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGR 507
SE + + E + + L T+ + E ++LEE E L QL +G+
Sbjct: 1306 SEAKIKVEELQRQLADASTQRGRLQTESGE--------LSRLLEEKEC---LISQLSRGK 1354
Query: 508 RLRQLQQLQQLR 519
L Q L++LR
Sbjct: 1355 AL-AAQSLEELR 1365
Score = 35.4 bits (80), Expect = 0.21
Identities = 61/337 (18%), Positives = 137/337 (40%), Gaps = 18/337 (5%)
Query: 208 RQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFR 267
R Q E++LA RA+L + + +E + + ++ L ++ D+
Sbjct: 890 RSAQAEEELAALRAEL-RGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLA 948
Query: 268 EGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQ 327
+ E L V E + ++ L D+E ++ R++K + + +DDL
Sbjct: 949 DAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDL-- 1006
Query: 328 QKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLA 387
+ L+K ++E + L + A L+E A+L + ++L +
Sbjct: 1007 ---KLTLAKAEKEKQATENKVKNLTEEMAA-------LDESVARLTKEKKALQEAHQQAL 1056
Query: 388 SEYLTPEEMVT-FKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRR 446
+ E+ V+ K K R+++ + ++ E + + L + + L+ +
Sbjct: 1057 GDLQAEEDRVSALTKAKLRLEQ-QVEDLECSLEQEKKLRMDTERAKRKLEGDLK-LTQES 1114
Query: 447 VSEVEEEKEPVPQPLPSDDTRVENMD--ISDEEEGGAPPPGSPQVLEEDEAELELQKQLE 504
V++ ++K+ + + L D+ + + + DE+ GA + L+ ELE + + E
Sbjct: 1115 VADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAE 1174
Query: 505 KGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEE 541
+ R R +Q + E++ E +++ G E
Sbjct: 1175 RAARARVEKQRAEAARELEELSERLEEAGGASAGQRE 1211
Score = 35.0 bits (79), Expect = 0.28
Identities = 116/524 (22%), Positives = 207/524 (39%), Gaps = 106/524 (20%)
Query: 33 REHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEA---RSSTHGRERSQAEPS 89
RE ++ R +GG+ +R+ R+R E G RR E A ++ R QAE +
Sbjct: 1190 RELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGA 1249
Query: 90 ----ERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAG 145
E+ ++ E S D + ++E + +A + +K
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKA----------SAEKLCR 1299
Query: 146 TKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKT-LGEDDPWLDDTAAWI 204
T E+ ++ I + EEL+ +LA A +R G+++T GE L++ I
Sbjct: 1300 TYEDQLSEAKI------KVEELQRQLADASTQR------GRLQTESGELSRLLEEKECLI 1347
Query: 205 ERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAID 264
QL + K LA A+ LEE+ ++ +EEE + + HA+
Sbjct: 1348 S---QLSRGKALA---AQSLEELRRQ------LEEESKAKS------------ALAHAVQ 1383
Query: 265 SFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDD 324
+ R D +L+E+ + E AE EL++ L + V
Sbjct: 1384 ALRH---------DCDLLREQHE----------EEAEAQAELQR-----LLSKANAEVAQ 1419
Query: 325 LAQQKPRSILSKYDEELEGERPHSFRL---EQGGTADGLRERELEEIRAKLRLQAQSLST 381
+ + + +E E ++ + RL E+G A + LE +AKLRLQ +S
Sbjct: 1420 WRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE--KAKLRLQTESEDV 1477
Query: 382 VGPRLASEYLTPEEMVTFKKTK--RRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRL 439
L E T KK + R + R++++E + R + + SR
Sbjct: 1478 T---LELERATSAAAALDKKQRHLERALEERRRQEEEMQR---------ELEAAQRESRG 1525
Query: 440 RGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAEL-- 497
G R+ EE + L ++ ++ +ISD + + S Q LE+ + L
Sbjct: 1526 LGTELFRLRHGHEEALEALETLKRENKNLQE-EISDLTDQVSLSGKSIQELEKTKKALEG 1584
Query: 498 ---ELQKQLEKGRRLRQLQQLQQLR---DSGEKVVEIVKKLESR 535
E+Q LE+ +L++ + LR + + E+ +KL +
Sbjct: 1585 EKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEK 1628
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 54.7 bits (130), Expect = 3e-07
Identities = 132/681 (19%), Positives = 246/681 (36%), Gaps = 147/681 (21%)
Query: 9 GEKEAAGTTAAAGTGGATEQPPRHREHKK--HKHRSGGSGGSGGERRKRSRERGGERGSG 66
GE AG + GGA + PP K + GGSGG G S G G+G
Sbjct: 171 GEGGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTG 230
Query: 67 RRGAEAEARSSTHGRERS-------QAEPSERRVKREKRDDGYEAAASSKTSSGDASS-- 117
R + + G S Q+E + +K+E+ AA + G +SS
Sbjct: 231 SRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSSRS 290
Query: 118 ------------LSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQRE 165
L++ + + A G + + +P L+++E
Sbjct: 291 SPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQE 350
Query: 166 ELREKLAAAKEK-RLLNQKLGKIKTLGED--DPWLDDTAAWIERSRQLQKEKDLAEKRAK 222
E++E++ +E+ L ++ +++T ++ D + ++ A ++ +++ E + A K +
Sbjct: 351 EMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQ---EMRHELERANKNCR 407
Query: 223 LLEEMDQEFGVSTLVEEEFGQ--------RRQDLYSARDLQGLTVEHAIDSFREGET--- 271
+L+ ++ L + G+ QDL A+D+ + + H +++ E T
Sbjct: 408 ILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDV-SVRLHHELENVEEKRTTTE 466
Query: 272 ---------MILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESV 322
+I K LQ E + + ++L K R K++ +KK P ED
Sbjct: 467 DENEKLRQQLIEVEIAKQALQNELEKMKELSL--KRRGSKDLPKSEKKAQQTPTEEDN-- 522
Query: 323 DDLAQQ----KPRSIL------------SKYDEELEGERPHSFRLEQ---GGTADGLRER 363
+DL Q K + L +++ EL+ R L+ G A G
Sbjct: 523 EDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPST 582
Query: 364 ELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDL 423
E++ +LRL + + +G R++ ++ + + + DDL
Sbjct: 583 REAELKLRLRLVEEEANILG--------------------RKIVELEVENRGLKAELDDL 622
Query: 424 LPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGA-- 481
+ DF R + + E ++ + L D+T + +++D EE
Sbjct: 623 -------RGDDFNGSANPLMREQSESLSELRQHL--QLVEDETELLRRNVADLEEQNKRI 673
Query: 482 ---------PPPGSPQVLEEDEAELE-LQKQLEKGR--------RLRQLQQLQQLRDSGE 523
G D A+ E LQ++L+ R ++ QLQ ++ S
Sbjct: 674 TAELNKYKYKSGGHDSARHHDNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNM 733
Query: 524 KVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMD 583
+ ++ L RG D D E AG +E ++
Sbjct: 734 QRYDLASHLGI--RGSPRDSDAESD-----------------------AGKKESDDDSRP 768
Query: 584 FERDEERSANGGSESDGEENI 604
R E G S+S+ NI
Sbjct: 769 PHRKREGPIGGESDSEEVRNI 789
Score = 48.5 bits (114), Expect = 2e-05
Identities = 129/574 (22%), Positives = 206/574 (35%), Gaps = 111/574 (19%)
Query: 10 EKEAAGTTAAAG--TGGATEQPPRHREHKKHK--------------HRSGGSGGSGGERR 53
E A T AA G G E+PPR E K GG+GG GER
Sbjct: 125 EAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGSGERE 184
Query: 54 KRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKRE---KRDDGYEAAASSKT 110
+ + RG +G A+ R + G S + S K R+ G A
Sbjct: 185 GGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSG 244
Query: 111 SSGD-------ASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQ 163
G S L K RA +++A K G+ ++ V P A
Sbjct: 245 GGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHA-KNGGGSSSR--SSPVSGPPA--- 298
Query: 164 REELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERS----RQLQKEKDLAEK 219
+ E LA A + G ++ AA S +QLQ+++++ E+
Sbjct: 299 ---VCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEE 355
Query: 220 RAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDK 279
KL EE + ++ E + R ++ R D+F E +D
Sbjct: 356 MEKLREE-------NETLKNEIDELRTEMDEMR-----------DTFFE--------EDA 389
Query: 280 GVLQEEEDVLVNVNLVDKERAEKN-----VELRKKKPDYLPYAEDESVDDLAQQKPRSIL 334
LQE L ERA KN LRK + L YA+ +D +L
Sbjct: 390 CQLQEMRHEL--------ERANKNCRILQYRLRKAERKRLRYAQTGEIDG-------ELL 434
Query: 335 SKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPE 394
+++L+ + S RL + E+ KLR Q + L +E +
Sbjct: 435 RSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMK 494
Query: 395 EMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEK 454
E+ ++ + + K KK ++ D+ D F R++++++++EK
Sbjct: 495 ELSLKRRGSKDLPKSEKKAQQTPTEEDN----EDLKCQLQFVKEEAALMRKKMAKIDKEK 550
Query: 455 EPVPQPLPSDDTRVENMDIS-DEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQ 513
+ L + ++D + E G PP EAEL+L RLR ++
Sbjct: 551 DRFEHELQKYRSFYGDLDSPLPKGEAGGPP-------STREAELKL--------RLRLVE 595
Query: 514 QLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPER 547
++ G K+VE LE RG + + D R
Sbjct: 596 --EEANILGRKIVE----LEVENRGLKAELDDLR 623
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 54.7 bits (130), Expect = 3e-07
Identities = 110/457 (24%), Positives = 186/457 (40%), Gaps = 87/457 (19%)
Query: 51 ERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKT 110
E R+R+ G ER EA A S T E Q E + EA SSK
Sbjct: 1494 EERERAEAEGRER-------EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 1546
Query: 111 SSGD-------ASSLSIEETNKLRA---------------KLGLKPLEVNAIKK------ 142
G A ++ + N LRA KL L+ + V A+K
Sbjct: 1547 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE-VTVQALKTQHERDL 1605
Query: 143 ----EAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLD 198
EAG + A + + + EE +++ A ++ L +L ++K
Sbjct: 1606 QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELK---------- 1655
Query: 199 DTAAWIERSRQLQKE--KDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQG 256
A + + Q ++E K L + +A++ E + T EE F Q R+ S + L+G
Sbjct: 1656 ---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRE---SEKRLKG 1709
Query: 257 LTVEHAIDSFREGETMILTLKDKGVLQEEEDVLV----NVNLVDKERAEKNVELRKKKPD 312
L E R E + + + + Q++ D + N NL E+ +L +
Sbjct: 1710 LEAE----VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1765
Query: 313 YLPYAEDE-SVDDLAQQKPRSILSKYDE---ELEGERPHSFRLEQGGTADGLRERELEEI 368
E+E S +L + R +L + + EL ER S + E G ER+++E+
Sbjct: 1766 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ---LERQIQEL 1822
Query: 369 RAKLR-----LQAQSLSTVGPRLASEYLTPEEMVTFKKTKRR------VKKIRKKEKEVV 417
R +L +A+ T+ L S+ EE + ++T+ R V++ K+ KEVV
Sbjct: 1823 RGRLGEEDAGARARHKMTIAA-LESKLAQAEEQLE-QETRERILSGKLVRRAEKRLKEVV 1880
Query: 418 VRADDLLPLGDQTQDGDFGSRLRGRG-RRRVSEVEEE 453
++ ++ + DQ +D LR + +R++ E EEE
Sbjct: 1881 LQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE 1917
Score = 47.4 bits (111), Expect = 5e-05
Identities = 134/657 (20%), Positives = 255/657 (38%), Gaps = 70/657 (10%)
Query: 81 RERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAI 140
+++S E E + + + ++ A + + + + E +L A+ L V+ +
Sbjct: 893 QQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSEL 952
Query: 141 KKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDT 200
+ G +EE L+Q + E A+E +L K+ T + + +D
Sbjct: 953 EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1012
Query: 201 AAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVE 260
+++ +L KE+ KLLE+ EF EEE + + L R T+
Sbjct: 1013 LLLEDQNSKLSKER-------KLLEDRLAEFSSQAAEEEE---KVKSLNKLRLKYEATIA 1062
Query: 261 HAIDSFREGETMILTL-KDKGVLQEEEDVLVNVNLVDKERAEK-NVELRKKKPDY---LP 315
D R+ E L K K L E L + ++RAE+ +L +K+ + L
Sbjct: 1063 DMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122
Query: 316 YAEDESVDDL----AQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAK 371
AEDE + ++ ++ L++ E+LE ER + E+ G ELE +R +
Sbjct: 1123 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG---EELEALRGE 1179
Query: 372 LRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQ 431
L +L + + +E+ KKT +I + + +R LG+ +
Sbjct: 1180 LE---DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQ-ELRQRHGQALGELAE 1235
Query: 432 DGDFGSRLRGRGRR-------RVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPP 484
+ R +G + VSE+ E + + R +++ +E G
Sbjct: 1236 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD 1295
Query: 485 G------SPQVLEEDEAELE-----LQKQLEKGRRL-RQLQQLQ-QLRDSGEKVVEIVK- 530
G + + L+ +AELE L + K RL ++L + QL D+ E + E +
Sbjct: 1296 GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1355
Query: 531 --KLESRQRGWEED-----EDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMD 583
L SR R E + E E + A A E ++ + R ++EE
Sbjct: 1356 KLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW----RRRQEEEAGA 1411
Query: 584 FERDEERSANGGSESDG-EENIGWSTVNLD-----EEKQQQDFSASSTTILDEEPIVN-- 635
E EE E++ + + T +D + QQ+ ++ + + +V+
Sbjct: 1412 LEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTL 1471
Query: 636 --RGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREE 690
+ LL + K + V++ R +A + + + A++++ REE
Sbjct: 1472 EKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSL--TRALEEEQEAREE 1526
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 54.7 bits (130), Expect = 3e-07
Identities = 110/457 (24%), Positives = 186/457 (40%), Gaps = 87/457 (19%)
Query: 51 ERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKT 110
E R+R+ G ER EA A S T E Q E + EA SSK
Sbjct: 1486 EERERAEAEGRER-------EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 1538
Query: 111 SSGD-------ASSLSIEETNKLRA---------------KLGLKPLEVNAIKK------ 142
G A ++ + N LRA KL L+ + V A+K
Sbjct: 1539 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE-VTVQALKTQHERDL 1597
Query: 143 ----EAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLD 198
EAG + A + + + EE +++ A ++ L +L ++K
Sbjct: 1598 QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELK---------- 1647
Query: 199 DTAAWIERSRQLQKE--KDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQG 256
A + + Q ++E K L + +A++ E + T EE F Q R+ S + L+G
Sbjct: 1648 ---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRE---SEKRLKG 1701
Query: 257 LTVEHAIDSFREGETMILTLKDKGVLQEEEDVLV----NVNLVDKERAEKNVELRKKKPD 312
L E R E + + + + Q++ D + N NL E+ +L +
Sbjct: 1702 LEAE----VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1757
Query: 313 YLPYAEDE-SVDDLAQQKPRSILSKYDE---ELEGERPHSFRLEQGGTADGLRERELEEI 368
E+E S +L + R +L + + EL ER S + E G ER+++E+
Sbjct: 1758 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ---LERQIQEL 1814
Query: 369 RAKLR-----LQAQSLSTVGPRLASEYLTPEEMVTFKKTKRR------VKKIRKKEKEVV 417
R +L +A+ T+ L S+ EE + ++T+ R V++ K+ KEVV
Sbjct: 1815 RGRLGEEDAGARARHKMTIAA-LESKLAQAEEQLE-QETRERILSGKLVRRAEKRLKEVV 1872
Query: 418 VRADDLLPLGDQTQDGDFGSRLRGRG-RRRVSEVEEE 453
++ ++ + DQ +D LR + +R++ E EEE
Sbjct: 1873 LQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE 1909
Score = 47.4 bits (111), Expect = 5e-05
Identities = 134/657 (20%), Positives = 255/657 (38%), Gaps = 70/657 (10%)
Query: 81 RERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAI 140
+++S E E + + + ++ A + + + + E +L A+ L V+ +
Sbjct: 885 QQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSEL 944
Query: 141 KKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDT 200
+ G +EE L+Q + E A+E +L K+ T + + +D
Sbjct: 945 EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1004
Query: 201 AAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVE 260
+++ +L KE+ KLLE+ EF EEE + + L R T+
Sbjct: 1005 LLLEDQNSKLSKER-------KLLEDRLAEFSSQAAEEEE---KVKSLNKLRLKYEATIA 1054
Query: 261 HAIDSFREGETMILTL-KDKGVLQEEEDVLVNVNLVDKERAEK-NVELRKKKPDY---LP 315
D R+ E L K K L E L + ++RAE+ +L +K+ + L
Sbjct: 1055 DMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1114
Query: 316 YAEDESVDDL----AQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAK 371
AEDE + ++ ++ L++ E+LE ER + E+ G ELE +R +
Sbjct: 1115 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG---EELEALRGE 1171
Query: 372 LRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQ 431
L +L + + +E+ KKT +I + + +R LG+ +
Sbjct: 1172 LE---DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQ-ELRQRHGQALGELAE 1227
Query: 432 DGDFGSRLRGRGRR-------RVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPP 484
+ R +G + VSE+ E + + R +++ +E G
Sbjct: 1228 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD 1287
Query: 485 G------SPQVLEEDEAELE-----LQKQLEKGRRL-RQLQQLQ-QLRDSGEKVVEIVK- 530
G + + L+ +AELE L + K RL ++L + QL D+ E + E +
Sbjct: 1288 GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1347
Query: 531 --KLESRQRGWEED-----EDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMD 583
L SR R E + E E + A A E ++ + R ++EE
Sbjct: 1348 KLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW----RRRQEEEAGA 1403
Query: 584 FERDEERSANGGSESDG-EENIGWSTVNLD-----EEKQQQDFSASSTTILDEEPIVN-- 635
E EE E++ + + T +D + QQ+ ++ + + +V+
Sbjct: 1404 LEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTL 1463
Query: 636 --RGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREE 690
+ LL + K + V++ R +A + + + A++++ REE
Sbjct: 1464 EKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSL--TRALEEEQEAREE 1518
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 54.7 bits (130), Expect = 3e-07
Identities = 110/457 (24%), Positives = 186/457 (40%), Gaps = 87/457 (19%)
Query: 51 ERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKT 110
E R+R+ G ER EA A S T E Q E + EA SSK
Sbjct: 1527 EERERAEAEGRER-------EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 1579
Query: 111 SSGD-------ASSLSIEETNKLRA---------------KLGLKPLEVNAIKK------ 142
G A ++ + N LRA KL L+ + V A+K
Sbjct: 1580 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE-VTVQALKTQHERDL 1638
Query: 143 ----EAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLD 198
EAG + A + + + EE +++ A ++ L +L ++K
Sbjct: 1639 QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELK---------- 1688
Query: 199 DTAAWIERSRQLQKE--KDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQG 256
A + + Q ++E K L + +A++ E + T EE F Q R+ S + L+G
Sbjct: 1689 ---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRE---SEKRLKG 1742
Query: 257 LTVEHAIDSFREGETMILTLKDKGVLQEEEDVLV----NVNLVDKERAEKNVELRKKKPD 312
L E R E + + + + Q++ D + N NL E+ +L +
Sbjct: 1743 LEAE----VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1798
Query: 313 YLPYAEDE-SVDDLAQQKPRSILSKYDE---ELEGERPHSFRLEQGGTADGLRERELEEI 368
E+E S +L + R +L + + EL ER S + E G ER+++E+
Sbjct: 1799 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ---LERQIQEL 1855
Query: 369 RAKLR-----LQAQSLSTVGPRLASEYLTPEEMVTFKKTKRR------VKKIRKKEKEVV 417
R +L +A+ T+ L S+ EE + ++T+ R V++ K+ KEVV
Sbjct: 1856 RGRLGEEDAGARARHKMTIAA-LESKLAQAEEQLE-QETRERILSGKLVRRAEKRLKEVV 1913
Query: 418 VRADDLLPLGDQTQDGDFGSRLRGRG-RRRVSEVEEE 453
++ ++ + DQ +D LR + +R++ E EEE
Sbjct: 1914 LQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE 1950
Score = 47.4 bits (111), Expect = 5e-05
Identities = 134/657 (20%), Positives = 255/657 (38%), Gaps = 70/657 (10%)
Query: 81 RERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAI 140
+++S E E + + + ++ A + + + + E +L A+ L V+ +
Sbjct: 926 QQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSEL 985
Query: 141 KKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDT 200
+ G +EE L+Q + E A+E +L K+ T + + +D
Sbjct: 986 EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1045
Query: 201 AAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVE 260
+++ +L KE+ KLLE+ EF EEE + + L R T+
Sbjct: 1046 LLLEDQNSKLSKER-------KLLEDRLAEFSSQAAEEEE---KVKSLNKLRLKYEATIA 1095
Query: 261 HAIDSFREGETMILTL-KDKGVLQEEEDVLVNVNLVDKERAEK-NVELRKKKPDY---LP 315
D R+ E L K K L E L + ++RAE+ +L +K+ + L
Sbjct: 1096 DMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1155
Query: 316 YAEDESVDDL----AQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAK 371
AEDE + ++ ++ L++ E+LE ER + E+ G ELE +R +
Sbjct: 1156 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG---EELEALRGE 1212
Query: 372 LRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQ 431
L +L + + +E+ KKT +I + + +R LG+ +
Sbjct: 1213 LE---DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQ-ELRQRHGQALGELAE 1268
Query: 432 DGDFGSRLRGRGRR-------RVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPP 484
+ R +G + VSE+ E + + R +++ +E G
Sbjct: 1269 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD 1328
Query: 485 G------SPQVLEEDEAELE-----LQKQLEKGRRL-RQLQQLQ-QLRDSGEKVVEIVK- 530
G + + L+ +AELE L + K RL ++L + QL D+ E + E +
Sbjct: 1329 GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1388
Query: 531 --KLESRQRGWEED-----EDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMD 583
L SR R E + E E + A A E ++ + R ++EE
Sbjct: 1389 KLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW----RRRQEEEAGA 1444
Query: 584 FERDEERSANGGSESDG-EENIGWSTVNLD-----EEKQQQDFSASSTTILDEEPIVN-- 635
E EE E++ + + T +D + QQ+ ++ + + +V+
Sbjct: 1445 LEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTL 1504
Query: 636 --RGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREE 690
+ LL + K + V++ R +A + + + A++++ REE
Sbjct: 1505 EKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSL--TRALEEEQEAREE 1559
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 54.3 bits (129), Expect = 4e-07
Identities = 114/476 (23%), Positives = 200/476 (42%), Gaps = 85/476 (17%)
Query: 154 DVINPMALRQREELREKLAAA---KEKRLLNQK-LGKIKTLGEDDPWLDDTAAWIERSRQ 209
+VI P + Q +E + +LA K R +Q+ L + +T+ E L+ S
Sbjct: 535 EVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLE--------SLN 586
Query: 210 LQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREG 269
+Q+EK+ E+R L+++ + E + ++ + L ++ TV ++ ++
Sbjct: 587 IQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKT 646
Query: 270 ETMILTLKDKGVLQEEE---DVLV--NVNLVDKERAEKNVELR--KKKPDYLPYA---ED 319
E KD + EE D ++ V ++KE+ E L+ +KK DY A E+
Sbjct: 647 ELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEE 706
Query: 320 ESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADG-------LRERELEEIRAKL 372
+ A ++ R E+ E ER + +LE+ + L +R+L +R K
Sbjct: 707 IPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKA 766
Query: 373 RLQA---QSLSTVGPRLASE-YLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGD 428
Q+ + L RLA E + EE +K +RR+ R+KE+E RA++ + L +
Sbjct: 767 ARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQM-LKE 825
Query: 429 QTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ 488
+ + R R +R E+ E +E V +
Sbjct: 826 REE------RERAERAKREEELREYQERVKK----------------------------- 850
Query: 489 VLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK 548
LEE E + + Q++LE R R+ ++ ++L DS + + +SR G + E RK
Sbjct: 851 -LEEVERK-KRQRELEIEERERRREEERRLGDSS------LSRKDSRW-GDRDSEGTWRK 901
Query: 549 GAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENI 604
G A SE+ R P E ++E RDEER G + D E ++
Sbjct: 902 GP---EADSEWRRG----PPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSL 950
Score = 36.6 bits (83), Expect = 0.095
Identities = 83/432 (19%), Positives = 168/432 (38%), Gaps = 65/432 (15%)
Query: 53 RKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSS 112
++ +R E R+ E R RE+ + ++K++ + E ++ +
Sbjct: 591 KEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGA 650
Query: 113 GDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLA 172
+ IE+ +L + +V ++KE K+E L++R + +EK
Sbjct: 651 KAFKDIDIEDLEELDPDF-IMAKQVEQLEKE---KKE-----------LQERLKNQEKKI 695
Query: 173 AAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIER------SRQLQKEKDLAEKR--AKLL 224
E+ +++ IK+ E+ + D W ++ + QL++EK L K +++L
Sbjct: 696 DYFERAKRLEEIPLIKSAYEEQR-IKDMDLWEQQEEERITTMQLEREKALEHKNRMSRML 754
Query: 225 EEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQE 284
E+ D L RQ +Y E + F E L E
Sbjct: 755 EDRD-------LFVMRLKAARQSVY----------EEKLKQFEER------------LAE 785
Query: 285 EEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGE 344
E + ++ + R+K+ + AE++ + + +++ R+ +K +EEL
Sbjct: 786 ERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKE-REERERAERAKREEELREY 844
Query: 345 RPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKR 404
+ +LE+ RE E+EE + + + + R S + + T++K
Sbjct: 845 QERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPE 904
Query: 405 RVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSD 464
+ R+ E R + +D D R RR+ + +E++EP +P D
Sbjct: 905 ADSEWRRGPPEKEWRR-------GEGRDEDRSHRRDEERPRRLGD-DEDREPSLRP---D 953
Query: 465 DTRVENMDISDE 476
D RV + D+
Sbjct: 954 DDRVPRRGMDDD 965
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 54.3 bits (129), Expect = 4e-07
Identities = 152/779 (19%), Positives = 303/779 (38%), Gaps = 85/779 (10%)
Query: 52 RRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRD-DGYEAAASSKT 110
+R S+ER G++ GR A+ + + HG + + P + + + + +G + + +
Sbjct: 427 QRPLSQERRGKQSVGRTFAKLQG--AAHGASCAHSRPPQPNIDGKVLETEGSQESTVIRA 484
Query: 111 SSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTA------DVINPMALRQR 164
S A S EE A L L+ A ++G K+ V P L+ +
Sbjct: 485 PSLGAQSKKEEEVKTATATLMLQN-RATATSPDSGAKKISVKTFPSASNTQATPDLLKGQ 543
Query: 165 EELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLL 224
+EL ++ K++L L + G D +D A + + +K + L + A
Sbjct: 544 QELTQQTNEETAKQILYNYLKE----GSTD---NDDATKRKVNLVFEKIQTLKSRAAGSA 596
Query: 225 EEMDQEFGVSTLVEEEFGQRRQDLYSARDLQG---LTVEHAIDSFREGETMILTLKDKGV 281
+ +Q ++ V++ Q+ + +LQ L V++ + E E M L++
Sbjct: 597 QGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEE--- 653
Query: 282 LQEEEDVLVNVNLVDKERAEKNV-ELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEE 340
L+ + + V N ++R E++ ELRK + + + + LS+ +E
Sbjct: 654 LRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDE 713
Query: 341 LEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFK 400
L+ + R E+G + L ++AK LQ ++ E+ +
Sbjct: 714 LDSAKRSEDR-EKGALIEEL-------LQAKQDLQDLLIAK-----------EEQEDLLR 754
Query: 401 KTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQP 460
K +R + ++ KE V D + + D +E++ +E V +
Sbjct: 755 KRERELTALKGALKEEVSSHDQEMDKLKEQYD---------------AELQALRESVEEA 799
Query: 461 LPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQ-QLQQLR 519
+ + + S++++ G ++L+E+ +L+ + + E RR+ QLQ Q++ L+
Sbjct: 800 TKNVEVLASRSNTSEQDQAGTEM--RVKLLQEENEKLQGRSE-ELERRVAQLQRQIEDLK 856
Query: 520 DSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQE 579
K E +KK E R EE RK + E L+ +EQ+
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQK 916
Query: 580 ELMDFERDEERSANGGSESDGE-ENIGWSTVNLDE--EKQQQDFSASSTTI-------LD 629
+L + ++E E EN W E +K+ D +S T LD
Sbjct: 917 QLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLD 976
Query: 630 EEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRRE 689
E NR A + + LE ++ +K ++ + + A D+ ++R+
Sbjct: 977 EYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQ 1036
Query: 690 EYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKE-AFRQLSHRFHGKGSGK-------M 741
+D + Y+ + K D+ R + E QL + +
Sbjct: 1037 LLEQTLKDLE----YELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERIS 1092
Query: 742 KTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK 800
++ +M++L E L ++ + D ++ L+ + K K+ I L GS +S + +
Sbjct: 1093 RSREQMEQLRNELLQERAARQDLECDKIS-LERQNKDLKSRIIHLEGSYRSSKEGLVVQ 1150
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 51.6 bits (122), Expect = 3e-06
Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 19/193 (9%)
Query: 27 EQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGER--GSGRRGAEAEARSSTHGRERS 84
E+ R RE +K + R G GER+K RER R + G E E R +ER
Sbjct: 65 EREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERG 124
Query: 85 QA--EPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKK 142
+ E ER K E++ + + K EE K R + K E +K
Sbjct: 125 RTSKEGKERERKEERKREERKERERKK-----------EEREKERERKERKKRE----RK 169
Query: 143 EAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAA 202
+ G KEE R+R K +++R +K K K + + D
Sbjct: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN 229
Query: 203 WIERSRQLQKEKD 215
W E+ R ++ K+
Sbjct: 230 WREKERGKRERKE 242
Score = 43.5 bits (101), Expect = 8e-04
Identities = 40/151 (26%), Positives = 57/151 (37%), Gaps = 17/151 (11%)
Query: 5 KKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKR--SRERG-- 60
K+ RG+KE G E+ RE KK + G E+RK+ +ERG
Sbjct: 78 KRERGKKEKKG-----------ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRT 126
Query: 61 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKRE--KRDDGYEAAASSKTSSGDASSL 118
+ G R E R RER + E + R ++E KR+ + +
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 119 SIEETNKLRAKLGLKPLEVNAIKKEAGTKEE 149
E N+ K + E KKE KEE
Sbjct: 187 KKRERNRKERKKERERKERRERKKERKKKEE 217
Score = 34.7 bits (78), Expect = 0.36
Identities = 43/195 (22%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 52 RRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTS 111
R++ +ER ER RR E R R+R R K+EK+ + + K
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKR-------ERGKKEKKGERKKEERERKKR 100
Query: 112 SGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKL 171
+ + EE K + K + + KE KEE + ++E R+K
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE--------RKERERKKE 152
Query: 172 AAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEF 231
KE+ +K + K +GE + + ER + ++E++ E++ + + +E
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEK----ERKERKKRERNRKERKKERERKERRER 208
Query: 232 GVSTLVEEEFGQRRQ 246
+EE + RQ
Sbjct: 209 KKERKKKEERKKERQ 223
Score = 30.8 bits (68), Expect = 5.2
Identities = 31/168 (18%), Positives = 68/168 (40%), Gaps = 15/168 (8%)
Query: 455 EPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQ 514
+P QP + R +I +EG + E E E +K+ + + ++ ++
Sbjct: 27 KPCTQPGWQSEIREREREIETRKEG------------KKERESERKKERREREKRKRERE 74
Query: 515 LQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGN 574
++ R+ G+K + +K E R+R E ++G + + G G
Sbjct: 75 KERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE 134
Query: 575 REEQ---EELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQD 619
R+E+ EE + ER +E + ++ +EE+++++
Sbjct: 135 RKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.128 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,404,356
Number of Sequences: 37866
Number of extensions: 1739125
Number of successful extensions: 14330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 819
Number of HSP's that attempted gapping in prelim test: 10266
Number of HSP's gapped (non-prelim): 3608
length of query: 800
length of database: 18,247,518
effective HSP length: 110
effective length of query: 690
effective length of database: 14,082,258
effective search space: 9716758020
effective search space used: 9716758020
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.