BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|108389176 tRNA splicing endonuclease 54 homolog [Homo sapiens] (526 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|108389176 tRNA splicing endonuclease 54 homolog [Homo sapiens] 1070 0.0 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 44 5e-04 gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 39 0.009 gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 39 0.015 gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchan... 38 0.020 gi|61102725 la related protein isoform 2 [Homo sapiens] 37 0.034 gi|239835767 developmental pluripotency associated 2 [Homo sapiens] 37 0.044 gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 36 0.099 gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] 36 0.099 gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] 36 0.099 gi|50428940 mediator complex subunit 25 [Homo sapiens] 36 0.099 gi|239752992 PREDICTED: hypothetical protein XP_002345322 [Homo ... 35 0.13 gi|239747550 PREDICTED: hypothetical protein XP_002347647 [Homo ... 35 0.13 gi|239741424 PREDICTED: hypothetical protein XP_002342197 [Homo ... 35 0.13 gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 35 0.13 gi|153791535 general control of amino acid synthesis 5-like 2 [H... 35 0.17 gi|150170670 piccolo isoform 2 [Homo sapiens] 35 0.17 gi|150378539 piccolo isoform 1 [Homo sapiens] 35 0.17 gi|50345997 E1A binding protein p300 [Homo sapiens] 35 0.22 gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 35 0.22 gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] 34 0.29 gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Ho... 34 0.29 gi|214831495 hypothetical protein LOC285679 [Homo sapiens] 34 0.29 gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 34 0.29 gi|153945765 mitogen-activated protein kinase kinase kinase 1 [H... 34 0.38 gi|113419362 PREDICTED: hypothetical protein [Homo sapiens] 34 0.38 gi|113418886 PREDICTED: hypothetical protein [Homo sapiens] 34 0.38 gi|113419893 PREDICTED: hypothetical protein [Homo sapiens] 34 0.38 gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 34 0.38 gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 34 0.38 >gi|108389176 tRNA splicing endonuclease 54 homolog [Homo sapiens] Length = 526 Score = 1070 bits (2768), Expect = 0.0 Identities = 526/526 (100%), Positives = 526/526 (100%) Query: 1 MEPEPEPAAVEVPAGRVLSARELFAARSRSQKLPQRSHGPKDFLPDGSAAQAERLRRCRE 60 MEPEPEPAAVEVPAGRVLSARELFAARSRSQKLPQRSHGPKDFLPDGSAAQAERLRRCRE Sbjct: 1 MEPEPEPAAVEVPAGRVLSARELFAARSRSQKLPQRSHGPKDFLPDGSAAQAERLRRCRE 60 Query: 61 ELWQLLAEQRVERLGSLVAAEWRPEEGFVELKSPAGKFWQTMGFSEQGRQRLHPEEALYL 120 ELWQLLAEQRVERLGSLVAAEWRPEEGFVELKSPAGKFWQTMGFSEQGRQRLHPEEALYL Sbjct: 61 ELWQLLAEQRVERLGSLVAAEWRPEEGFVELKSPAGKFWQTMGFSEQGRQRLHPEEALYL 120 Query: 121 LECGSIHLFHQDLPLSIQEAYQLLLTDHTVTFLQYQVFSHLKRLGYVVRRFQPSSVLSPY 180 LECGSIHLFHQDLPLSIQEAYQLLLTDHTVTFLQYQVFSHLKRLGYVVRRFQPSSVLSPY Sbjct: 121 LECGSIHLFHQDLPLSIQEAYQLLLTDHTVTFLQYQVFSHLKRLGYVVRRFQPSSVLSPY 180 Query: 181 ERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQC 240 ERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQC Sbjct: 181 ERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQC 240 Query: 241 PEEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQ 300 PEEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQ Sbjct: 241 PEEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQ 300 Query: 301 ISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAEAA 360 ISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAEAA Sbjct: 301 ISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAEAA 360 Query: 361 QFQEDVNADPEVQRCSSWREYKELLQRRQVQRSQRRAPHLWGQPVTPLLSPGQASSPAVV 420 QFQEDVNADPEVQRCSSWREYKELLQRRQVQRSQRRAPHLWGQPVTPLLSPGQASSPAVV Sbjct: 361 QFQEDVNADPEVQRCSSWREYKELLQRRQVQRSQRRAPHLWGQPVTPLLSPGQASSPAVV 420 Query: 421 LQHISVLQTTHLPDGGARLLEKSGGLEIIFDVYQADAVATFRKNNPGKPYARMCISGFDE 480 LQHISVLQTTHLPDGGARLLEKSGGLEIIFDVYQADAVATFRKNNPGKPYARMCISGFDE Sbjct: 421 LQHISVLQTTHLPDGGARLLEKSGGLEIIFDVYQADAVATFRKNNPGKPYARMCISGFDE 480 Query: 481 PVPDLCSLKRLSYQSGDVPLIFALVDHGDISFYSFRDFTLPQDVGH 526 PVPDLCSLKRLSYQSGDVPLIFALVDHGDISFYSFRDFTLPQDVGH Sbjct: 481 PVPDLCSLKRLSYQSGDVPLIFALVDHGDISFYSFRDFTLPQDVGH 526 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 43.5 bits (101), Expect = 5e-04 Identities = 45/198 (22%), Positives = 78/198 (39%), Gaps = 19/198 (9%) Query: 197 DGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGPGG 256 + K S++ P ++ + N + +S A +SP P PS P +E P + P Sbjct: 513 EAKESPSAAGPEDKSQSKRRASN--EKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTD 570 Query: 257 PFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHTLLR 316 L P+P P + + R E A KRR EQ + + L+ Sbjct: 571 AAVLTSPPAPAP-PVTPSKPMAGTTDREEATRLLAEKRRQAREQ-----REREEQERRLQ 624 Query: 317 APAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAEAAQFQEDVNADPEVQRCS 376 A + + RE +A + +R+ + RRE + E AQ +++ E +R Sbjct: 625 AERDKRMREEQLAREAEARA------EREAEARRREEQEAREKAQAEQE-----EQERLQ 673 Query: 377 SWREYKELLQRRQVQRSQ 394 +E E R + +R + Sbjct: 674 KQKEEAEARSREEAERQR 691 Score = 34.3 bits (77), Expect = 0.29 Identities = 46/183 (25%), Positives = 73/183 (39%), Gaps = 31/183 (16%) Query: 222 QPKSLAASSPPPCSQPSQCPEEKPQESSPMKGPGGPFQL-------LGSLGPSPGPAREG 274 +P SPPP + P+ P MK QL G +GP P P +E Sbjct: 26 RPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQE- 84 Query: 275 VGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHTLLRAPAPELLPANVAGRETDA 334 ES +E K R P A R + P+P +PA +D+ Sbjct: 85 -----ESPSSE------AKSRGPTPPAMGPRDARPPRRS--SQPSPTAVPA------SDS 125 Query: 335 ESWCQKLNQ--RKEKLSRREREHHAEAAQFQEDVNADPEVQRCSSWREYKELLQRRQVQR 392 Q++ + + KL++ RE A+ ++ V + E ++ + RE K+L +RR+ Sbjct: 126 PPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKE-EKAKALRE-KQLQERRRRLE 183 Query: 393 SQR 395 QR Sbjct: 184 EQR 186 Score = 32.7 bits (73), Expect = 0.84 Identities = 56/246 (22%), Positives = 85/246 (34%), Gaps = 50/246 (20%) Query: 199 KRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGPGGPF 258 K K+ K A A + SL+ + +SP S E P+ + P + Sbjct: 415 KEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSW 474 Query: 259 QLLGSLGPSPGPAR---------EGVGCSWESGR------AENGVTGAG-------KRRW 296 S PSPGP G S GR A+ + AG KRR Sbjct: 475 HRPASPCPSPGPGHTLPPKPPSPRGTTAS-PKGRVRRKEEAKESPSAAGPEDKSQSKRRA 533 Query: 297 NFEQIS------------FPNMASDSRH-------------TLLRAPAPELLPANVAGRE 331 + E+ S P A + T APAP + P+ Sbjct: 534 SNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGT 593 Query: 332 TDAESWCQKL-NQRKEKLSRREREHHAEAAQFQEDVN-ADPEVQRCSSWREYKELLQRRQ 389 TD E + L +R++ +RERE Q + D + ++ R + R +E RR+ Sbjct: 594 TDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRR 653 Query: 390 VQRSQR 395 ++ R Sbjct: 654 EEQEAR 659 >gi|239754474 PREDICTED: similar to mucin [Homo sapiens] Length = 417 Score = 39.3 bits (90), Expect = 0.009 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 10/100 (10%) Query: 196 GDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGP- 254 G G+R+ S SSP + ++A+ + AA++P P S+ + + KPQ+ P + P Sbjct: 223 GTGQRRGSRSSPSADQQRAQDREEE------AAAAPAPTSRGHRTEKRKPQQ--PQRRPA 274 Query: 255 GGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKR 294 GG Q GS G SP ++G E A T +G R Sbjct: 275 GGTGQRRGS-GYSPSADQQGAQDREEEAAAAPAPTSSGHR 313 Score = 35.4 bits (80), Expect = 0.13 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 10/100 (10%) Query: 196 GDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGP- 254 G G+R+ S SSP + ++A+ + AA++P P S+ + + K Q+ P + P Sbjct: 117 GTGQRRGSRSSPSADQQRAQDREEE------AAAAPVPTSRGHRTEKRKRQQ--PQRRPA 168 Query: 255 GGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKR 294 GG Q GS G SP ++G E A T G R Sbjct: 169 GGTGQRRGS-GSSPSADQQGAQDREEEAAAAPAPTSRGHR 207 Score = 30.8 bits (68), Expect = 3.2 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 8/99 (8%) Query: 196 GDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGPG 255 G G+R+ S SSP + + A+ + AA++P P S+ + + KPQ+ + G Sbjct: 170 GTGQRRGSGSSPSADQQGAQDREEE------AAAAPAPTSRGHRTEKRKPQQPQ-CRPAG 222 Query: 256 GPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKR 294 G Q GS SP ++ E A T G R Sbjct: 223 GTGQRRGSRS-SPSADQQRAQDREEEAAAAPAPTSRGHR 260 >gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] Length = 1006 Score = 38.5 bits (88), Expect = 0.015 Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 7/101 (6%) Query: 201 KRSSSSPRSINKKAKALDNSLQPKSLAAS------SPPPCSQPSQCPEEKPQESSPMKGP 254 +R S+PR I + ++ + + + AS + P P P P P Sbjct: 3 RRKQSNPRQIKRSLGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPTSP 62 Query: 255 GGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRR 295 GGP +L G P P P E G W V G+RR Sbjct: 63 GGPKELEGQ-EPEPRPTEEEPGSPWSGPDELEPVVQDGQRR 102 >gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchange factor 4 [Homo sapiens] Length = 368 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 23/110 (20%) Query: 227 AASSPPPCSQPS---------------QCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPA 271 AA++PPP +QPS QCP E ++S G S G SPG Sbjct: 196 AAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSSS----SSAGLSPGSD 251 Query: 272 RE--GVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHTLLRAPA 319 + GV C G G+ GA R W+ E + D+ AP+ Sbjct: 252 SDSSGVVCGGRGGNG--GMRGAVSRSWSLESLRSATAGKDAAIPAPHAPS 299 >gi|61102725 la related protein isoform 2 [Homo sapiens] Length = 1096 Score = 37.4 bits (85), Expect = 0.034 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 6/105 (5%) Query: 190 VQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESS 249 +Q E G RK+ +P + +P A PPC++P + + + S Sbjct: 16 LQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERES 75 Query: 250 PMKGPGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKR 294 P P QL G+ GP+ EG G G A G GAG+R Sbjct: 76 PR-----PLQLPGAEGPAISDGEEGGGEPGAGGGAA-GAAGAGRR 114 >gi|239835767 developmental pluripotency associated 2 [Homo sapiens] Length = 298 Score = 37.0 bits (84), Expect = 0.044 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 12/101 (11%) Query: 299 EQISFPNMASDSRHTLLRAPAPELLPA-NVAGRETDAESWCQKLN-----QRKEKLSRRE 352 EQ + P A R + P P +LP N R+T WCQ+L ++ E R Sbjct: 68 EQFTAPQKA---RCKIPALPLPTILPPINKVCRDT-LRDWCQQLGLSTNGKKIEVYLRLH 123 Query: 353 REHHAEAAQFQEDVNADPEVQRCSSWREYKELLQRRQVQRS 393 R + E Q +++ + +QRCS R+ K + +R ++QRS Sbjct: 124 RHAYPEQRQDMPEMSQETRLQRCS--RKRKAVTKRARLQRS 162 >gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] Length = 625 Score = 35.8 bits (81), Expect = 0.099 Identities = 57/224 (25%), Positives = 82/224 (36%), Gaps = 42/224 (18%) Query: 202 RSSSSPRSINKKAKALDNSLQPKSLAASS------------PPPCSQPSQCPEEKPQESS 249 R+ S++ ++ + +L +S A+SS PP S + CP SS Sbjct: 240 RTGRKSHSLDSLSRRREGALSSESGASSSSYSGESLRELRWPPRASARNSCPAGSA--SS 297 Query: 250 PMKGPGGPFQL-----------LGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNF 298 PG P L LG L SP A+ V RAE G+ G +R Sbjct: 298 TTNAPGRPSALTLVPITGRSFSLGDLSHSPQTAQH-VERIVRQVRAERGLRGVPERD--- 353 Query: 299 EQISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAE 358 +I+ +A LL + R W + K++ R ERE Sbjct: 354 RKIAALMLARHQEELLL-----------LEQRAAAHGQWELQRVHAKQRREREEREKQRA 402 Query: 359 AAQFQEDVNADPEVQRCSSWREYKELLQRRQVQ--RSQRRAPHL 400 Q + A E +R RE +E +RRQ Q RS+ R L Sbjct: 403 LEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRREL 446 >gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] Length = 627 Score = 35.8 bits (81), Expect = 0.099 Identities = 57/224 (25%), Positives = 82/224 (36%), Gaps = 42/224 (18%) Query: 202 RSSSSPRSINKKAKALDNSLQPKSLAASS------------PPPCSQPSQCPEEKPQESS 249 R+ S++ ++ + +L +S A+SS PP S + CP SS Sbjct: 242 RTGRKSHSLDSLSRRREGALSSESGASSSSYSGESLRELRWPPRASARNSCPAGSA--SS 299 Query: 250 PMKGPGGPFQL-----------LGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNF 298 PG P L LG L SP A+ V RAE G+ G +R Sbjct: 300 TTNAPGRPSALTLVPITGRSFSLGDLSHSPQTAQH-VERIVRQVRAERGLRGVPERD--- 355 Query: 299 EQISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAE 358 +I+ +A LL + R W + K++ R ERE Sbjct: 356 RKIAALMLARHQEELLL-----------LEQRAAAHGQWELQRVHAKQRREREEREKQRA 404 Query: 359 AAQFQEDVNADPEVQRCSSWREYKELLQRRQVQ--RSQRRAPHL 400 Q + A E +R RE +E +RRQ Q RS+ R L Sbjct: 405 LEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRREL 448 >gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] Length = 627 Score = 35.8 bits (81), Expect = 0.099 Identities = 57/224 (25%), Positives = 82/224 (36%), Gaps = 42/224 (18%) Query: 202 RSSSSPRSINKKAKALDNSLQPKSLAASS------------PPPCSQPSQCPEEKPQESS 249 R+ S++ ++ + +L +S A+SS PP S + CP SS Sbjct: 242 RTGRKSHSLDSLSRRREGALSSESGASSSSYSGESLRELRWPPRASARNSCPAGSA--SS 299 Query: 250 PMKGPGGPFQL-----------LGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNF 298 PG P L LG L SP A+ V RAE G+ G +R Sbjct: 300 TTNAPGRPSALTLVPITGRSFSLGDLSHSPQTAQH-VERIVRQVRAERGLRGVPERD--- 355 Query: 299 EQISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAE 358 +I+ +A LL + R W + K++ R ERE Sbjct: 356 RKIAALMLARHQEELLL-----------LEQRAAAHGQWELQRVHAKQRREREEREKQRA 404 Query: 359 AAQFQEDVNADPEVQRCSSWREYKELLQRRQVQ--RSQRRAPHL 400 Q + A E +R RE +E +RRQ Q RS+ R L Sbjct: 405 LEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRREL 448 >gi|50428940 mediator complex subunit 25 [Homo sapiens] Length = 747 Score = 35.8 bits (81), Expect = 0.099 Identities = 37/127 (29%), Positives = 47/127 (37%), Gaps = 12/127 (9%) Query: 221 LQPKSLAASSPPPCSQPSQCPEEKPQES-SPMKGPGGPFQLLGSLGP----SPGPAREGV 275 L P A PPP SQPS P +P PG P + G++ P P PA+ G Sbjct: 328 LPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAP-SMAGTVAPGGVSGPSPAQLGA 386 Query: 276 GCSWESGRAENGVTG-AGKRRWNFEQISFPNMASDSRHTLLRAPAPELLPANVAGRETDA 334 N + +G W + P AS +T L P + N G Sbjct: 387 PALGGQQSVSNKLLAWSGVLEWQEK----PKPASVDANTKLTRSLPCQVYVN-HGENLKT 441 Query: 335 ESWCQKL 341 E W QKL Sbjct: 442 EQWPQKL 448 >gi|239752992 PREDICTED: hypothetical protein XP_002345322 [Homo sapiens] Length = 277 Score = 35.4 bits (80), Expect = 0.13 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 15/114 (13%) Query: 178 SPYERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAAS--SPPPCS 235 SP + + + +G R IN K+ SL+P AAS S P CS Sbjct: 146 SPSRTSFHGETQIPGAPEGRKPPSCPGKDQRDINYKSSGTPRSLEPDEGAASWASSPVCS 205 Query: 236 -----QPSQCP-----EEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSW 279 +PS P Q+S P+ PFQ PGP +G SW Sbjct: 206 PVQGKRPSPSPGAISFSSVHQQSQPVTATVAPFQYRLQTDQKPGPLSQG---SW 256 >gi|239747550 PREDICTED: hypothetical protein XP_002347647 [Homo sapiens] Length = 277 Score = 35.4 bits (80), Expect = 0.13 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 15/114 (13%) Query: 178 SPYERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAAS--SPPPCS 235 SP + + + +G R IN K+ SL+P AAS S P CS Sbjct: 146 SPSRTSFHGETQIPGAPEGRKPPSCPGKDQRDINYKSSGTPRSLEPDEGAASWASSPVCS 205 Query: 236 -----QPSQCP-----EEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSW 279 +PS P Q+S P+ PFQ PGP +G SW Sbjct: 206 PVQGKRPSPSPGAISFSSVHQQSQPVTATVAPFQYRLQTDQKPGPLSQG---SW 256 >gi|239741424 PREDICTED: hypothetical protein XP_002342197 [Homo sapiens] Length = 277 Score = 35.4 bits (80), Expect = 0.13 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 15/114 (13%) Query: 178 SPYERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAAS--SPPPCS 235 SP + + + +G R IN K+ SL+P AAS S P CS Sbjct: 146 SPSRTSFHGETQIPGAPEGRKPPSCPGKDQRDINYKSSGTPRSLEPDEGAASWASSPVCS 205 Query: 236 -----QPSQCP-----EEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSW 279 +PS P Q+S P+ PFQ PGP +G SW Sbjct: 206 PVQGKRPSPSPGAISFSSVHQQSQPVTATVAPFQYRLQTDQKPGPLSQG---SW 256 >gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo sapiens] Length = 1905 Score = 35.4 bits (80), Expect = 0.13 Identities = 58/232 (25%), Positives = 80/232 (34%), Gaps = 29/232 (12%) Query: 105 SEQGRQRLHPEEALYL-----------LECGSIHLFHQDLPLSIQEAYQLLLTDHTVTFL 153 SEQ + +L PE L+ L+ L + PLS+ ++ L +++L Sbjct: 1214 SEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQSQHDLSQSAFLSWL 1273 Query: 154 QYQVFSHLKRLGYVVRRFQPSSVLSPYERQLNLD-ASVQHLEDGDGKRKRSSSSPRSI-- 210 Q SH L SSVL+P LD A Q E+ + SS P+++ Sbjct: 1274 S-QTQSHSSLLS--------SSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQALWF 1324 Query: 211 NKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGP 270 N A+ N+ A S P P Q KP P P Q + P Sbjct: 1325 NISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLAGLAP 1384 Query: 271 AREGVGCSWESGRAENGVTGAG--KRRWNFEQISFPNMASDSRHTLLRAPAP 320 R + + G TG G KRR F M L P P Sbjct: 1385 KRR----AGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVP 1432 >gi|153791535 general control of amino acid synthesis 5-like 2 [Homo sapiens] Length = 837 Score = 35.0 bits (79), Expect = 0.17 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Query: 204 SSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGPGGPFQLLGS 263 ++ PR + A A + P +A P P P+ P P S+ G GGP G Sbjct: 13 AAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGST---GTGGPGVGSGG 69 Query: 264 LGPSPGPAREGVGCSWESGRAENGVTG 290 G PAR G+ + + + V G Sbjct: 70 AGSGGDPARPGLSQQQRASQRKAQVRG 96 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 35.0 bits (79), Expect = 0.17 Identities = 57/230 (24%), Positives = 85/230 (36%), Gaps = 19/230 (8%) Query: 152 FLQYQVFSHLKRLGYVVRRFQPSSVLSPYE-----RQLNLDASVQHLEDGDGKRKRSSSS 206 F+ + + L LG +R PY R + +SV L D KR SSSS Sbjct: 4255 FMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGL-DLSIKRDSSSSS 4313 Query: 207 PRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKP------QESSPMKGPGGPFQL 260 R ++A+ALD S S +A + P SQ P +E SP+ G P + Sbjct: 4314 LRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGM 4373 Query: 261 ----LGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHTLLR 316 G L P R+ G S + + + R I+F + D +H + Sbjct: 4374 ARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAF--IMDDFQHAMSD 4431 Query: 317 APAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAEAAQFQEDV 366 + A L + ES + + KL R H +Q QE + Sbjct: 4432 SEAYHLRREETDWFDKPRESRLENGHGLDRKLPER-LVHSRPLSQHQEQI 4480 Score = 31.2 bits (69), Expect = 2.4 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 8/81 (9%) Query: 201 KRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQ------PSQCPEEKPQESSPMKGP 254 +R +S P++ K+A + SL + S PP Q P+Q P + + P K P Sbjct: 275 QRDASRPQT--KQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP 332 Query: 255 GGPFQLLGSLGPSPGPAREGV 275 P L L PG + V Sbjct: 333 AQPSGLTKPLAQQPGTVKPPV 353 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 35.0 bits (79), Expect = 0.17 Identities = 57/230 (24%), Positives = 85/230 (36%), Gaps = 19/230 (8%) Query: 152 FLQYQVFSHLKRLGYVVRRFQPSSVLSPYE-----RQLNLDASVQHLEDGDGKRKRSSSS 206 F+ + + L LG +R PY R + +SV L D KR SSSS Sbjct: 4255 FMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGL-DLSIKRDSSSSS 4313 Query: 207 PRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKP------QESSPMKGPGGPFQL 260 R ++A+ALD S S +A + P SQ P +E SP+ G P + Sbjct: 4314 LRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGM 4373 Query: 261 ----LGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHTLLR 316 G L P R+ G S + + + R I+F + D +H + Sbjct: 4374 ARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAF--IMDDFQHAMSD 4431 Query: 317 APAPELLPANVAGRETDAESWCQKLNQRKEKLSRREREHHAEAAQFQEDV 366 + A L + ES + + KL R H +Q QE + Sbjct: 4432 SEAYHLRREETDWFDKPRESRLENGHGLDRKLPER-LVHSRPLSQHQEQI 4480 Score = 31.2 bits (69), Expect = 2.4 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 8/81 (9%) Query: 201 KRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQ------PSQCPEEKPQESSPMKGP 254 +R +S P++ K+A + SL + S PP Q P+Q P + + P K P Sbjct: 275 QRDASRPQT--KQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP 332 Query: 255 GGPFQLLGSLGPSPGPAREGV 275 P L L PG + V Sbjct: 333 AQPSGLTKPLAQQPGTVKPPV 353 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 34.7 bits (78), Expect = 0.22 Identities = 37/149 (24%), Positives = 56/149 (37%), Gaps = 10/149 (6%) Query: 183 QLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSL--QPKSLAASSPPPCSQPSQC 240 +L S +L G G + +S + L NS+ P + A + P + Sbjct: 83 ELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNMGMGTSG 142 Query: 241 PEEKPQES-----SPMKGPGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRR 295 P + P +S SP+ P + G +PG G G + NG GAG+ R Sbjct: 143 PNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGR 202 Query: 296 WNFEQISFPNMASDSRHTLLRAPAPELLP 324 N + +PN S LL P + P Sbjct: 203 QNMQ---YPNPGMGSAGNLLTEPLQQGSP 228 >gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] Length = 796 Score = 34.7 bits (78), Expect = 0.22 Identities = 35/126 (27%), Positives = 46/126 (36%), Gaps = 11/126 (8%) Query: 223 PKSLAASSPPPCSQPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSWESG 282 P S A PPP P P +P PGGP L G+ P S S Sbjct: 265 PASAAVLPPPP---PHALGSRGPPTPAPPGAPGGPACLGGT--PGVSATSSSASSSTSSS 319 Query: 283 RAENGVTGAGKRRWNFEQISFPNMASDSRHTLLRAPAPELLPANVAGRETDAESWCQKLN 342 AE GV GKR + +S + + + A A L ++ R AE W K Sbjct: 320 VAEVGVGAGGKRPGS---VSSTDQERELKEKQRNAEALAELSESLRNR---AEEWASKPK 373 Query: 343 QRKEKL 348 ++ L Sbjct: 374 MVRDTL 379 >gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] Length = 1962 Score = 34.3 bits (77), Expect = 0.29 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 204 SSSPRSINKKAK-ALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKGP 254 +S+ S N AK A N+ QP+ P QP Q P+ +PQ+ P + P Sbjct: 75 TSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQP 126 Score = 29.3 bits (64), Expect = 9.2 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 12/112 (10%) Query: 178 SPYERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQP 237 S Y L+ A + D K S S + + + L PK++ A S PP Sbjct: 1679 SNYNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLT 1738 Query: 238 SQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPAREGVGCSW---ESGRAEN 286 Q P ++SP++ GG G S AR G SW SGR N Sbjct: 1739 GQKPPLSTWDNSPLRIGGG-------WGNS--DARYTPGSSWGESSSGRITN 1781 >gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Homo sapiens] Length = 1288 Score = 34.3 bits (77), Expect = 0.29 Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 8/84 (9%) Query: 166 YVVRRFQPSSVLSPYERQLNLDASVQHLEDGDGKRKRSSSSPRSINKKAKALDNSLQP-- 223 +++R F+P L + L D +Q GKR RS SSPR + + A S P Sbjct: 882 FLLRTFEPDPRLRASAQTLLGDPFLQ-----PGKRSRSPSSPRHAPRPSDAPSASPTPSA 936 Query: 224 KSLAASSPPPCSQ-PSQCPEEKPQ 246 S S PC Q PSQ P P+ Sbjct: 937 NSTTQSQTFPCPQAPSQHPPSPPK 960 >gi|214831495 hypothetical protein LOC285679 [Homo sapiens] Length = 277 Score = 34.3 bits (77), Expect = 0.29 Identities = 44/180 (24%), Positives = 70/180 (38%), Gaps = 26/180 (14%) Query: 141 YQLLLTD----HTVTFLQYQVFSHLKRLG---YVVRRFQPSSVLSPYERQLNLDASVQHL 193 Y++LL + TFL + L R G ++ R+ +P V P A ++ Sbjct: 95 YRILLKELENLEIYTFLSKKCLKKLSREGSSHHLPRQVRPGPVYKP--------APARNH 146 Query: 194 EDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQES-SPMK 252 G+ K S +S ++ +A + P S+ +S PS KP+E P+K Sbjct: 147 RPRGGRGKASPTSFH-VSPRAPLAPLASMPSSVPKTSVESLGSPSSLSSSKPREPLCPLK 205 Query: 253 GPGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRH 312 P +L P+P + E +G + +GR G F Q N A RH Sbjct: 206 HPSHQ-PPASTLSPNPTSSTESLGETPHAGRWRQGS--------RFPQPGCANAAGRIRH 256 >gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] Length = 818 Score = 34.3 bits (77), Expect = 0.29 Identities = 30/105 (28%), Positives = 40/105 (38%), Gaps = 10/105 (9%) Query: 197 DGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEE------KPQESSP 250 DG RK S R ++ A S + ++ + PP QP P E P P Sbjct: 507 DGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCA--PPSMQPPAPPAELAAPLPSPLPEQP 564 Query: 251 MKGPGGPFQLLGSLGPSPGPAREGVGCSWE--SGRAENGVTGAGK 293 + P P LG PGP R S E G A+ G G+ + Sbjct: 565 LDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGSSQ 609 >gi|153945765 mitogen-activated protein kinase kinase kinase 1 [Homo sapiens] Length = 1512 Score = 33.9 bits (76), Expect = 0.38 Identities = 43/164 (26%), Positives = 65/164 (39%), Gaps = 25/164 (15%) Query: 194 EDGDGKRKRSSSSPRSINKKAKALDNSLQPKSLAASSPPPCSQPSQCPEEKPQESSPMKG 253 E G G R+R+ R + K + L + L ++ PP S S PE P +++ G Sbjct: 46 EAGSGGRERADWRRRQLRKVRSVELDQLPEQPLFLAASPPASSTSPSPE--PADAA---G 100 Query: 254 PGGPFQLLGSLGPSPGPAREGVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHT 313 G FQ + P +R G + ++G S P A Sbjct: 101 SGTGFQPVAVPPPHGAASRGGAHLTESVAAPDSGA-------------SSPAAAEPGEK- 146 Query: 314 LLRAPAPELLPANV-AGRETDAESWCQ---KLNQRKEKLSRRER 353 RAPA E PA AGRE + + + K++ R E+ RE+ Sbjct: 147 --RAPAAEPSPAAAPAGREMENKETLKGLHKMDDRPEERMIREK 188 >gi|113419362 PREDICTED: hypothetical protein [Homo sapiens] Length = 248 Score = 33.9 bits (76), Expect = 0.38 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 230 SPPPCS-QPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPA 271 +PPPC +P + P+E P GPG P +L PG A Sbjct: 4 APPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALSGGPGRA 46 >gi|113418886 PREDICTED: hypothetical protein [Homo sapiens] Length = 248 Score = 33.9 bits (76), Expect = 0.38 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 230 SPPPCS-QPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPA 271 +PPPC +P + P+E P GPG P +L PG A Sbjct: 4 APPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALSGGPGRA 46 >gi|113419893 PREDICTED: hypothetical protein [Homo sapiens] Length = 248 Score = 33.9 bits (76), Expect = 0.38 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 230 SPPPCS-QPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPA 271 +PPPC +P + P+E P GPG P +L PG A Sbjct: 4 APPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALSGGPGRA 46 >gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] Length = 1337 Score = 33.9 bits (76), Expect = 0.38 Identities = 39/186 (20%), Positives = 62/186 (33%), Gaps = 17/186 (9%) Query: 232 PPCSQPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGP---AREGVGCSWESGRAENGV 288 PP P CP P +P PF + P P P + V + G + + Sbjct: 118 PPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNF 177 Query: 289 TGAGKRRWNFEQISFPNMASDSRHTLLRAPAPELLPANVAGRETDA----------ESWC 338 + SF A++S R P LP + R + Sbjct: 178 PPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHS 237 Query: 339 QKLNQRKEKLSRRER----EHHAEAAQFQEDVNADPEVQRCSSWREYKELLQRRQVQRSQ 394 +R L RRER + + ++++ D + R S+ +E + R R Sbjct: 238 HGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDN 297 Query: 395 RRAPHL 400 RR+P L Sbjct: 298 RRSPSL 303 >gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] Length = 1374 Score = 33.9 bits (76), Expect = 0.38 Identities = 39/186 (20%), Positives = 62/186 (33%), Gaps = 17/186 (9%) Query: 232 PPCSQPSQCPEEKPQESSPMKGPGGPFQLLGSLGPSPGP---AREGVGCSWESGRAENGV 288 PP P CP P +P PF + P P P + V + G + + Sbjct: 118 PPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNF 177 Query: 289 TGAGKRRWNFEQISFPNMASDSRHTLLRAPAPELLPANVAGRETDA----------ESWC 338 + SF A++S R P LP + R + Sbjct: 178 PPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHS 237 Query: 339 QKLNQRKEKLSRRER----EHHAEAAQFQEDVNADPEVQRCSSWREYKELLQRRQVQRSQ 394 +R L RRER + + ++++ D + R S+ +E + R R Sbjct: 238 HGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDN 297 Query: 395 RRAPHL 400 RR+P L Sbjct: 298 RRSPSL 303 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,476,247 Number of Sequences: 37866 Number of extensions: 1355509 Number of successful extensions: 7852 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 228 Number of HSP's that attempted gapping in prelim test: 7416 Number of HSP's gapped (non-prelim): 652 length of query: 526 length of database: 18,247,518 effective HSP length: 107 effective length of query: 419 effective length of database: 14,195,856 effective search space: 5948063664 effective search space used: 5948063664 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.