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Search of human proteins with 10835067
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10835067 autoantigen La [Homo sapiens]
(408 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10835067 autoantigen La [Homo sapiens] 818 0.0
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ... 84 3e-16
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ... 84 3e-16
gi|61102725 la related protein isoform 2 [Homo sapiens] 67 4e-11
gi|39725634 la related protein isoform 1 [Homo sapiens] 67 4e-11
gi|30061565 La ribonucleoprotein domain family member 2 isoform ... 59 1e-08
gi|30061569 La ribonucleoprotein domain family member 2 isoform ... 59 1e-08
gi|30061567 La ribonucleoprotein domain family member 2 isoform ... 59 1e-08
gi|37537710 La ribonucleoprotein domain family, member 6 isoform... 57 3e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 48 1e-05
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 46 7e-05
gi|28416946 myosin 18A isoform a [Homo sapiens] 45 2e-04
gi|4506467 radixin [Homo sapiens] 44 3e-04
gi|157266334 tubby like protein 1 [Homo sapiens] 43 6e-04
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 42 0.001
gi|7657234 small acidic protein isoform a [Homo sapiens] 42 0.001
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 41 0.002
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 41 0.002
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 41 0.002
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 41 0.002
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 41 0.002
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 41 0.002
gi|40353738 c-Mpl binding protein isoform a [Homo sapiens] 40 0.003
gi|40353736 c-Mpl binding protein isoform c [Homo sapiens] 40 0.003
gi|40353740 c-Mpl binding protein isoform b [Homo sapiens] 40 0.003
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ... 40 0.004
gi|46276863 parathymosin [Homo sapiens] 40 0.005
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 40 0.005
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 40 0.005
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 39 0.006
>gi|10835067 autoantigen La [Homo sapiens]
Length = 408
Score = 818 bits (2113), Expect = 0.0
Identities = 408/408 (100%), Positives = 408/408 (100%)
Query: 1 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNR 60
MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNR
Sbjct: 1 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNR 60
Query: 61 LTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPT 120
LTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPT
Sbjct: 61 LTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPT 120
Query: 121 DATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDL 180
DATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDL
Sbjct: 121 DATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDL 180
Query: 181 LILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDL 240
LILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDL
Sbjct: 181 LILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDL 240
Query: 241 DDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKE 300
DDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKE
Sbjct: 241 DDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKE 300
Query: 301 VTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGK 360
VTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGK
Sbjct: 301 VTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGK 360
Query: 361 KTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ 408
KTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ
Sbjct: 361 KTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ 408
>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
sapiens]
Length = 582
Score = 83.6 bits (205), Expect = 3e-16
Identities = 67/228 (29%), Positives = 117/228 (51%), Gaps = 20/228 (8%)
Query: 3 ENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQI-KLDEGWVPLEIMIKFNRLNRL 61
E ++ + A I Q++++FGD NL +D+FL+EQI K +G+V + +++ FN++ +L
Sbjct: 24 EKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKL 83
Query: 62 TTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTD 121
TTD +I AL S ++E+ + T+IRR KPL E D R+VY++ P +
Sbjct: 84 TTDGKLIARALRSS--AVVELDLEGTRIRR--KKPL----GERPKDEDERTVYVELLPKN 135
Query: 122 ATLDDIKEWLEDKGQVLNIQMRRTLHKAF---KGSIFVVFDSIESAKKFVETPGQKYKET 178
I+ G V+ I + +K+ KG FV F++ E A K +E +E
Sbjct: 136 VNHSWIERVFGKCGNVVYISIPH--YKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEA 193
Query: 179 DLLILFKDDYFAK--KNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMK 224
K F K KN+ +V + + K++++ + K E++ + K
Sbjct: 194 PR----KPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRMKKEDNIQAK 237
Score = 30.0 bits (66), Expect = 3.9
Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
Query: 258 EIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTW--EVLEGEVEKEAL 315
E+ ++D + G E FK A+ N ++ NK+ W E+L G+ E+
Sbjct: 480 EVLYVDLLEGDTECHARFKTPED-----AQAVINAYTEI-NKKHCWKLEILSGDHEQRYW 533
Query: 316 KKIIEDQQESLNKWKSKGR 334
+KI+ D+Q LN+ + K R
Sbjct: 534 QKILVDRQAKLNQPREKKR 552
>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
sapiens]
Length = 582
Score = 83.6 bits (205), Expect = 3e-16
Identities = 67/228 (29%), Positives = 117/228 (51%), Gaps = 20/228 (8%)
Query: 3 ENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQI-KLDEGWVPLEIMIKFNRLNRL 61
E ++ + A I Q++++FGD NL +D+FL+EQI K +G+V + +++ FN++ +L
Sbjct: 24 EKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKL 83
Query: 62 TTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTD 121
TTD +I AL S ++E+ + T+IRR KPL E D R+VY++ P +
Sbjct: 84 TTDGKLIARALRSS--AVVELDLEGTRIRR--KKPL----GERPKDEDERTVYVELLPKN 135
Query: 122 ATLDDIKEWLEDKGQVLNIQMRRTLHKAF---KGSIFVVFDSIESAKKFVETPGQKYKET 178
I+ G V+ I + +K+ KG FV F++ E A K +E +E
Sbjct: 136 VNHSWIERVFGKCGNVVYISIPH--YKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEA 193
Query: 179 DLLILFKDDYFAK--KNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMK 224
K F K KN+ +V + + K++++ + K E++ + K
Sbjct: 194 PR----KPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRMKKEDNIQAK 237
Score = 30.0 bits (66), Expect = 3.9
Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
Query: 258 EIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTW--EVLEGEVEKEAL 315
E+ ++D + G E FK A+ N ++ NK+ W E+L G+ E+
Sbjct: 480 EVLYVDLLEGDTECHARFKTPED-----AQAVINAYTEI-NKKHCWKLEILSGDHEQRYW 533
Query: 316 KKIIEDQQESLNKWKSKGR 334
+KI+ D+Q LN+ + K R
Sbjct: 534 QKILVDRQAKLNQPREKKR 552
>gi|61102725 la related protein isoform 2 [Homo sapiens]
Length = 1096
Score = 66.6 bits (161), Expect = 4e-11
Identities = 39/96 (40%), Positives = 59/96 (61%), Gaps = 4/96 (4%)
Query: 13 LEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEAL 72
L+ I QIEYYF NL RD FL+ ++ D G++P+ ++ F+R+ LTTD ++I AL
Sbjct: 403 LKDYIKRQIEYYFSVDNLERDFFLRRKMDAD-GFLPITLIASFHRVQALTTDISLIFAAL 461
Query: 73 SKSKAELMEISEDKTKIRRSPSK-PLPEVTDEYKND 107
SK ++EI ++K + R P K PLP + D + D
Sbjct: 462 KDSK--VVEIVDEKVRRREEPEKWPLPPIVDYSQTD 495
>gi|39725634 la related protein isoform 1 [Homo sapiens]
Length = 1019
Score = 66.6 bits (161), Expect = 4e-11
Identities = 39/96 (40%), Positives = 59/96 (61%), Gaps = 4/96 (4%)
Query: 13 LEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEAL 72
L+ I QIEYYF NL RD FL+ ++ D G++P+ ++ F+R+ LTTD ++I AL
Sbjct: 326 LKDYIKRQIEYYFSVDNLERDFFLRRKMDAD-GFLPITLIASFHRVQALTTDISLIFAAL 384
Query: 73 SKSKAELMEISEDKTKIRRSPSK-PLPEVTDEYKND 107
SK ++EI ++K + R P K PLP + D + D
Sbjct: 385 KDSK--VVEIVDEKVRRREEPEKWPLPPIVDYSQTD 418
>gi|30061565 La ribonucleoprotein domain family member 2 isoform 2
[Homo sapiens]
Length = 522
Score = 58.5 bits (140), Expect = 1e-08
Identities = 35/89 (39%), Positives = 56/89 (62%), Gaps = 4/89 (4%)
Query: 11 AALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVE 70
A L+ I QIEYYF NL RD FL+ ++ ++G++P+ ++ F R+ LTT+ N+I+E
Sbjct: 213 ALLKEYIKRQIEYYFSVENLERDFFLRGKMD-EQGFLPISLIAGFQRVQALTTNLNLILE 271
Query: 71 ALSKSKAELMEISEDKTKIRRSPSK-PLP 98
AL S +EI ++K + + P K P+P
Sbjct: 272 ALKDSTE--VEIVDEKMRKKIEPEKWPIP 298
>gi|30061569 La ribonucleoprotein domain family member 2 isoform 3
[Homo sapiens]
Length = 358
Score = 58.5 bits (140), Expect = 1e-08
Identities = 35/89 (39%), Positives = 56/89 (62%), Gaps = 4/89 (4%)
Query: 11 AALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVE 70
A L+ I QIEYYF NL RD FL+ ++ ++G++P+ ++ F R+ LTT+ N+I+E
Sbjct: 213 ALLKEYIKRQIEYYFSVENLERDFFLRGKMD-EQGFLPISLIAGFQRVQALTTNLNLILE 271
Query: 71 ALSKSKAELMEISEDKTKIRRSPSK-PLP 98
AL S +EI ++K + + P K P+P
Sbjct: 272 ALKDSTE--VEIVDEKMRKKIEPEKWPIP 298
>gi|30061567 La ribonucleoprotein domain family member 2 isoform 1
[Homo sapiens]
Length = 914
Score = 58.5 bits (140), Expect = 1e-08
Identities = 35/89 (39%), Positives = 56/89 (62%), Gaps = 4/89 (4%)
Query: 11 AALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVE 70
A L+ I QIEYYF NL RD FL+ ++ ++G++P+ ++ F R+ LTT+ N+I+E
Sbjct: 213 ALLKEYIKRQIEYYFSVENLERDFFLRGKMD-EQGFLPISLIAGFQRVQALTTNLNLILE 271
Query: 71 ALSKSKAELMEISEDKTKIRRSPSK-PLP 98
AL S +EI ++K + + P K P+P
Sbjct: 272 ALKDSTE--VEIVDEKMRKKIEPEKWPIP 298
>gi|37537710 La ribonucleoprotein domain family, member 6 isoform 1
[Homo sapiens]
Length = 491
Score = 57.0 bits (136), Expect = 3e-08
Identities = 29/83 (34%), Positives = 51/83 (61%), Gaps = 3/83 (3%)
Query: 16 KICHQIEYYFGDFNLPRDKFLKEQIKLDE-GWVPLEIMIKFNRLNRLTTDFNVIVEALSK 74
K+ QIE+YF D NL +D FL + ++ ++ G+V ++++ F ++ LT D+ AL
Sbjct: 95 KLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKY 154
Query: 75 SKAELMEISEDKTKIRRSPSKPL 97
S ++E++ED K+RR+ PL
Sbjct: 155 S--VVLELNEDHRKVRRTTPVPL 175
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 48.1 bits (113), Expect = 1e-05
Identities = 53/223 (23%), Positives = 95/223 (42%), Gaps = 31/223 (13%)
Query: 194 EERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCL--LKFSGDLDDQTCREDLHI 251
+E ++ E + RA+ E+E K K+EE K LEEK + K G+ +Q
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKI------ 413
Query: 252 LFSNHGEIKWIDFVRGAKEGI---ILFK---EKAKEALGKAKDANNGNLQLRNKEVTWEV 305
E KW++ + ++ + +L K EK + K + + +E+ E
Sbjct: 414 ------EGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEK 467
Query: 306 LEGEVEKEALKKIIEDQQESLNKWKSKGRRF---KGKGKGNKAAQPGSGKGKVQFQGKKT 362
++ + E + K D+++ + KS+ F K K N ++PG G+ K+
Sbjct: 468 IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG---GRASVDTKEA 524
Query: 363 KFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGA 405
+ A E + E ++R R ET+ EE +QK + A
Sbjct: 525 EGAPQVEAGKRLEE-----LRRRRGETESEEFEKLKQKQQEAA 562
Score = 36.2 bits (82), Expect = 0.055
Identities = 41/217 (18%), Positives = 99/217 (45%), Gaps = 9/217 (4%)
Query: 191 KKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDD-QTCREDL 249
K+ E ++ ++EA+ R + + E +K+ ++ EEK + + ++ + RE+
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEE 321
Query: 250 HILFSNHGEIKWIDFVRGAKEGIILFKE--KAKEALGKAKDANNGNLQLRNKEVTWEVLE 307
IK + R A+E + +E +A E + K+ + R + E +
Sbjct: 322 KRAAEERQRIKEEE-KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 308 GEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQF-----QGKKT 362
+VE++ K +E+++ ++ + K KG + + K +G + + + K+Q QG++
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK 440
Query: 363 KFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQ 399
+ ++ E+ T + ++E K++ K++
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEE 477
Score = 33.9 bits (76), Expect = 0.27
Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 173 QKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKI 230
+K K+ + + KK EER++ E + R KQE EA +KL E+ E + L+E+I
Sbjct: 552 EKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE-EADRKLREEEEKRRLKEEI 608
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 45.8 bits (107), Expect = 7e-05
Identities = 51/187 (27%), Positives = 77/187 (41%), Gaps = 25/187 (13%)
Query: 112 SVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETP 171
+VYIK F D + +K+ G+ L++++ KG FV FDS E+AKK VE
Sbjct: 191 NVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEM 250
Query: 172 GQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIG 231
+ L+ + R Q KVE + KQ E ++ E G
Sbjct: 251 NGRDINGQLIFV-----------GRAQKKVERQAELKQMFEQLKR----------ERIRG 289
Query: 232 C--LLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVR--GAKEGIILFKEKAKEALGKAK 287
C + + +LDD E L FS+ G I + ++ G +G L + E KA
Sbjct: 290 CQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAM 349
Query: 288 DANNGNL 294
NG +
Sbjct: 350 TEMNGRI 356
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 44.7 bits (104), Expect = 2e-04
Identities = 85/379 (22%), Positives = 162/379 (42%), Gaps = 66/379 (17%)
Query: 11 AALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVE 70
AA++A+ ++E D +L D K + L+E L+ K NRL D + E
Sbjct: 1701 AAVKARKAMEVE--IEDLHLQIDDIAKAKTALEEQLSRLQ-REKNEIQNRLEEDQEDMNE 1757
Query: 71 ALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEW 130
+ K KA + + S D +I ++ L E E K +++ + ++ + ++ +++
Sbjct: 1758 LMKKHKAAVAQASRDLAQINDLQAQ-LEEANKE-KQELQEKLQALQ-----SQVEFLEQS 1810
Query: 131 LEDKGQVLNIQMR-RTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKET-DLLILFKDDY 188
+ DK V + + R L + + K +E+ + KE + L +D
Sbjct: 1811 MVDKSLVSRQEAKIRELETRLEFE--------RTQVKRLESLASRLKENMEKLTEERDQR 1862
Query: 189 FAKKNEERKQNK-VEAKLR---------AKQEQEAKQKLEE-DAEMKSLEEKIGCLLKFS 237
A +N E++QNK ++ +LR A++E EA +K E + +++SLE
Sbjct: 1863 IAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA-------- 1914
Query: 238 GDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLR 297
+Q+ + DL + F G+++ A + ++ ++ + +D + +
Sbjct: 1915 ----NQSLQADLKLAFKRIGDLQ-------AAIEDEMESDENEDLINSLQDMVTKYQKRK 1963
Query: 298 NKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGK--V 355
NK LEG+ + ++ +ED+ + + W S K KG A+ GS K
Sbjct: 1964 NK------LEGDSDVDS---ELEDRVDGVKSWLS-----KNKGPSKAASDDGSLKSSSPT 2009
Query: 356 QFQGKKTKFASDDEHDEHD 374
+ SDDEHD D
Sbjct: 2010 SYWKSLAPDRSDDEHDPLD 2028
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 43.9 bits (102), Expect = 3e-04
Identities = 54/232 (23%), Positives = 100/232 (43%), Gaps = 35/232 (15%)
Query: 190 AKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDL 249
A+ EE+ Q ++E RA+ E E K++ + E + +E + L++ +++QT +
Sbjct: 307 AQAREEKHQKQLE---RAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQK 363
Query: 250 HILFSNHGEIKWIDFVRGAKEGII-LFKEKAKEALGKAKDANNGNLQLRNKE-VTWEVLE 307
+ ++ + AKE L KE+ K+ A Q++N+E + E+ E
Sbjct: 364 ELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAE 423
Query: 308 GEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFAS- 366
+ L++ + ++E +W+ K AAQ K K + KT ++
Sbjct: 424 FTAKIALLEEAKKKKEEEATEWQHKAF----------AAQEDLEKTKEEL---KTVMSAP 470
Query: 367 ------------DDEHDEHDENGATGPVKRARE----ETDKEEPASKQQKTE 402
++EHDEHDEN A + + E +EE ++ QK E
Sbjct: 471 PPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNE 522
>gi|157266334 tubby like protein 1 [Homo sapiens]
Length = 542
Score = 42.7 bits (99), Expect = 6e-04
Identities = 55/200 (27%), Positives = 83/200 (41%), Gaps = 23/200 (11%)
Query: 171 PGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKI 230
P Q + F D AKK + R+ V A+ E+E +++ EED E ++ E+K
Sbjct: 78 PAQARAPQTVYARFLRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKE 137
Query: 231 GCLL--------KFSGDLDD-----QTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKE 277
LL K S DL + Q R DL ++ + A EG + K
Sbjct: 138 KILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKT 197
Query: 278 KAKEALGKAKDANNGNLQLRNKEVT-WEVLEGEVEKEALK---------KIIEDQQESLN 327
K K + KD + R + V EG +K+ALK K E+++E+
Sbjct: 198 KKKGSGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAAT 257
Query: 328 KWKSKGRRFKGKGKGNKAAQ 347
K ++ K KGKG K A+
Sbjct: 258 VIKKSNQKGKAKGKGKKKAK 277
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/257 (22%), Positives = 102/257 (39%), Gaps = 42/257 (16%)
Query: 161 IESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEED 220
IE KK E ++ K + + D + + ER K E + ++Q+ ++ +
Sbjct: 721 IERRKKHKERDLKRGKSRESV----DSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDR 776
Query: 221 AEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVR------GAKEGIIL 274
+ S + K ++ RE+ F + DFV G G
Sbjct: 777 SRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDK-SRLGTKDFVGPSERGGGRARGTFQ 835
Query: 275 FKEKAK-----EALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQ--ESLN 327
F+ + + G + +N + Q RN+E W + E ++ K + D + E +
Sbjct: 836 FRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEW---DPEYTPKSKKYYLHDDREGEGSD 892
Query: 328 KWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKT-------KFASDDEHDEHDENGATG 380
KW S+GR G+G A P G+G+ F+ T KF+ ++ E DE+G
Sbjct: 893 KWVSRGR---GRG-----AFP-RGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTEN 943
Query: 381 PVKRAREETDKEEPASK 397
REE D +P ++
Sbjct: 944 -----REEKDNIQPTTE 955
>gi|7657234 small acidic protein isoform a [Homo sapiens]
Length = 183
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 11/129 (8%)
Query: 276 KEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRR 335
K+K +G K + G L + + + T GE +K+ +++ Q+S++ K GR
Sbjct: 38 KQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDS-KLSGRY 96
Query: 336 FKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPV-KRAREETDKEEP 394
+ G G + G+G V A DD+ D+ D P + E++KEE
Sbjct: 97 RRHCGLGFSEVEDHDGEGDV---------AGDDDDDDDDSPDPESPDDSESDSESEKEES 147
Query: 395 ASKQQKTEN 403
A + Q E+
Sbjct: 148 AEELQAAEH 156
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 41.2 bits (95), Expect = 0.002
Identities = 70/371 (18%), Positives = 139/371 (37%), Gaps = 63/371 (16%)
Query: 93 PSKPLPEVTDEYKNDVK--------------NRSVYIKGFPTDATLDDIKEWLEDKGQVL 138
P + PE TD K K N +VY+ G P D T+D+ + + G ++
Sbjct: 101 PQEKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIM 160
Query: 139 ----NIQMRRTLHKAFKGSI-------FVVFDSIESAKKFV---ETPGQKYKETDLLILF 184
+ + L+K +G++ ++ +S+E A K + E G K
Sbjct: 161 RDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQL 220
Query: 185 KDDYFA-KKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDD- 242
K +Y A KK ++ K K + ++ KQ ++ + M+ I + D +D
Sbjct: 221 KGEYDASKKKKKCKDYKKKLSMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDD 280
Query: 243 ----QTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRN 298
REDL + S G+I+ + +G+ + E +G
Sbjct: 281 PLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGR-WFGG 339
Query: 299 KEVTWEVLEGEVEKEALKKIIEDQQESLNKWK--------SKGRRFKGKGKGNKAAQPGS 350
+++T + +G + + +++ +++E L W+ ++G R ++ A P
Sbjct: 340 RQITAQAWDGTTDYQ-VEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSR 398
Query: 351 GK--------GKVQFQGKKT-----------KFASDDEHDEHDENGATGPVKRAREETDK 391
+ K+ Q T KF ++ E +E + K + E +
Sbjct: 399 ARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA 458
Query: 392 EEPASKQQKTE 402
EE +++ E
Sbjct: 459 EEGCPEKESEE 469
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 41.2 bits (95), Expect = 0.002
Identities = 70/371 (18%), Positives = 139/371 (37%), Gaps = 63/371 (16%)
Query: 93 PSKPLPEVTDEYKNDVK--------------NRSVYIKGFPTDATLDDIKEWLEDKGQVL 138
P + PE TD K K N +VY+ G P D T+D+ + + G ++
Sbjct: 101 PQEKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIM 160
Query: 139 ----NIQMRRTLHKAFKGSI-------FVVFDSIESAKKFV---ETPGQKYKETDLLILF 184
+ + L+K +G++ ++ +S+E A K + E G K
Sbjct: 161 RDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQL 220
Query: 185 KDDYFA-KKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDD- 242
K +Y A KK ++ K K + ++ KQ ++ + M+ I + D +D
Sbjct: 221 KGEYDASKKKKKCKDYKKKLSMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDD 280
Query: 243 ----QTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRN 298
REDL + S G+I+ + +G+ + E +G
Sbjct: 281 PLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGR-WFGG 339
Query: 299 KEVTWEVLEGEVEKEALKKIIEDQQESLNKWK--------SKGRRFKGKGKGNKAAQPGS 350
+++T + +G + + +++ +++E L W+ ++G R ++ A P
Sbjct: 340 RQITAQAWDGTTDYQ-VEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSR 398
Query: 351 GK--------GKVQFQGKKT-----------KFASDDEHDEHDENGATGPVKRAREETDK 391
+ K+ Q T KF ++ E +E + K + E +
Sbjct: 399 ARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA 458
Query: 392 EEPASKQQKTE 402
EE +++ E
Sbjct: 459 EEGCPEKESEE 469
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 40.8 bits (94), Expect = 0.002
Identities = 51/226 (22%), Positives = 96/226 (42%), Gaps = 15/226 (6%)
Query: 185 KDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQT 244
+++ + ++ E R+Q K K K ++ ++ E++ +M+ EEK+ ++
Sbjct: 271 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW--------RQEKR 322
Query: 245 CREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWE 304
RE L E++ +R +E + +EK E K ++ R +E WE
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQE--EKMWRQEERLWE 380
Query: 305 VLEGEVEKEALKKIIEDQQ-ESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTK 363
+ E+E + E++ E + + K R + + K + + + K+Q Q KKT+
Sbjct: 381 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR 440
Query: 364 FASDDEHDEHDENGATGPVKRAREETD-KEEPASKQQKTENGAGDQ 408
D E +E K+ REE + E K QK E +Q
Sbjct: 441 ---DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 483
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/149 (29%), Positives = 65/149 (43%), Gaps = 21/149 (14%)
Query: 112 SVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETP 171
+VYIK F + + +KE G+ L++++ R + KG FV ++ E A K VE
Sbjct: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE- 250
Query: 172 GQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEE-DAEMKSLEEKI 230
KE I+F R Q KVE ++ E K+K E+ E S + +
Sbjct: 251 -MNGKEISGKIIFVG---------RAQKKVE------RQAELKRKFEQLKQERISRYQGV 294
Query: 231 GCLLKFSGDLDDQTCREDLHILFSNHGEI 259
+K +LDD E L FS G I
Sbjct: 295 NLYIK---NLDDTIDDEKLRKEFSPFGSI 320
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/149 (29%), Positives = 65/149 (43%), Gaps = 21/149 (14%)
Query: 112 SVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETP 171
+VYIK F + + +KE G+ L++++ R + KG FV ++ E A K VE
Sbjct: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE- 250
Query: 172 GQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEE-DAEMKSLEEKI 230
KE I+F R Q KVE ++ E K+K E+ E S + +
Sbjct: 251 -MNGKEISGKIIFVG---------RAQKKVE------RQAELKRKFEQLKQERISRYQGV 294
Query: 231 GCLLKFSGDLDDQTCREDLHILFSNHGEI 259
+K +LDD E L FS G I
Sbjct: 295 NLYIK---NLDDTIDDEKLRKEFSPFGSI 320
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/149 (29%), Positives = 65/149 (43%), Gaps = 21/149 (14%)
Query: 112 SVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETP 171
+VYIK F + + +KE G+ L++++ R + KG FV ++ E A K VE
Sbjct: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE- 250
Query: 172 GQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEE-DAEMKSLEEKI 230
KE I+F R Q KVE ++ E K+K E+ E S + +
Sbjct: 251 -MNGKEISGKIIFVG---------RAQKKVE------RQAELKRKFEQLKQERISRYQGV 294
Query: 231 GCLLKFSGDLDDQTCREDLHILFSNHGEI 259
+K +LDD E L FS G I
Sbjct: 295 NLYIK---NLDDTIDDEKLRKEFSPFGSI 320
>gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]
Length = 724
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 11/103 (10%)
Query: 7 NEKMAALEAKIC--HQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTD 64
N ++ + K C Q+E+ F NL +D +L Q+ D+ ++P+ + + +LTTD
Sbjct: 111 NSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQ-FIPIWTVANMEEIKKLTTD 169
Query: 65 FNVIVEALSKSKAELMEISEDKTKIRRSPS------KPLPEVT 101
++I+E L S ++++ E K+R S + +PE T
Sbjct: 170 PDLILEVLRSS--PMVQVDEKGEKVRPSHKRCIVILREIPETT 210
>gi|40353736 c-Mpl binding protein isoform c [Homo sapiens]
Length = 653
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 11/103 (10%)
Query: 7 NEKMAALEAKIC--HQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTD 64
N ++ + K C Q+E+ F NL +D +L Q+ D+ ++P+ + + +LTTD
Sbjct: 111 NSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQ-FIPIWTVANMEEIKKLTTD 169
Query: 65 FNVIVEALSKSKAELMEISEDKTKIRRSPS------KPLPEVT 101
++I+E L S ++++ E K+R S + +PE T
Sbjct: 170 PDLILEVLRSS--PMVQVDEKGEKVRPSHKRCIVILREIPETT 210
>gi|40353740 c-Mpl binding protein isoform b [Homo sapiens]
Length = 730
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 11/103 (10%)
Query: 7 NEKMAALEAKIC--HQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTD 64
N ++ + K C Q+E+ F NL +D +L Q+ D+ ++P+ + + +LTTD
Sbjct: 117 NSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQ-FIPIWTVANMEEIKKLTTD 175
Query: 65 FNVIVEALSKSKAELMEISEDKTKIRRSPS------KPLPEVT 101
++I+E L S ++++ E K+R S + +PE T
Sbjct: 176 PDLILEVLRSS--PMVQVDEKGEKVRPSHKRCIVILREIPETT 216
>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
[Homo sapiens]
Length = 621
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/181 (27%), Positives = 82/181 (45%), Gaps = 24/181 (13%)
Query: 184 FKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSL-------EEKI---GCL 233
FK++ AKK E+K K EAK ++EQEAK+K + AE+++ EE++ L
Sbjct: 283 FKEEEKAKKEAEKKA-KAEAK---RKEQEAKEK-QRQAELEAARLAKEKEEEEVRQQALL 337
Query: 234 LKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGN 293
K D+ + +++ L ++ W F E + + +E K +
Sbjct: 338 AKKEKDIQKKAIKKERQKLRNSCKT--WNHFSDNEAERVKMMEEVEK----LCDRLELAS 391
Query: 294 LQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGR-RFKGKGKGNKAAQPGSGK 352
LQ N+ +T EV K AL+K IE+ E + K K + R + K + + G G
Sbjct: 392 LQCLNETLT--SCTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGN 449
Query: 353 G 353
G
Sbjct: 450 G 450
>gi|46276863 parathymosin [Homo sapiens]
Length = 102
Score = 39.7 bits (91), Expect = 0.005
Identities = 29/98 (29%), Positives = 54/98 (55%), Gaps = 9/98 (9%)
Query: 309 EVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGK-GKVQFQGKKTKFASD 367
E+ + LK+ E +E ++ + K + + G + + + + G+ + +G++ D
Sbjct: 11 ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEE----ED 66
Query: 368 DEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGA 405
+E +E D+ G +KRA EE D+ +P K+QKTENGA
Sbjct: 67 EEEEEEDDEGPA--LKRAAEEEDEADP--KRQKTENGA 100
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 39.7 bits (91), Expect = 0.005
Identities = 51/224 (22%), Positives = 98/224 (43%), Gaps = 31/224 (13%)
Query: 192 KNEERKQNKVEAKLRAKQEQ--EAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDL 249
++EER++ + + K R + E+ E +++L E E K K G+ +Q RE
Sbjct: 670 QDEEREKGEKD-KGRGEMERPGEGEKELAEKEEWK----------KRDGEEQEQKEREQG 718
Query: 250 HILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGE 309
H N + + G E +E+ +E G+ K+ G E +EGE
Sbjct: 719 HQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEG-----------EEVEGE 767
Query: 310 VEKEALKKIIEDQQESLNKWKSKGRRFKG-----KGKGNKAAQPGSGKGKVQFQGKKTKF 364
EKE ++ E++ K + +G + +G +G+G + + G +G +GK +
Sbjct: 768 REKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGERE 827
Query: 365 ASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ 408
++E + +E G + EE + E +++ E G G++
Sbjct: 828 EEEEEGEGEEEEGEGEEEEGEGEEEEGE--GKGEEEGEEGEGEE 869
Score = 38.9 bits (89), Expect = 0.008
Identities = 56/257 (21%), Positives = 112/257 (43%), Gaps = 44/257 (17%)
Query: 168 VETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQK--------LEE 219
+E PG+ KE + K+++ + EE++Q + E + ++ QE ++ EE
Sbjct: 686 MERPGEGEKE----LAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEE 741
Query: 220 DAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKA 279
+ + + EEK G G GE + ++ R +EG +E+A
Sbjct: 742 EGDREEEEEKEG-----EG---------------KEEGEGEEVEGEREKEEGERKKEERA 781
Query: 280 -KEALGKAK-DANNGNLQL-----RNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSK 332
KE G+ + D G + KE EV GEVE+ ++ E+++ + + +
Sbjct: 782 GKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE 841
Query: 333 GRRFKGKGKGNKAAQPGSGKGKVQ-FQGKKTKFASDDEHDEHDENGATGPVKRAREETDK 391
G +G+G+ + G GKG+ + +G+ + + E + +E G + E ++
Sbjct: 842 GEEEEGEGE----EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Query: 392 EEPASKQQKTENGAGDQ 408
EE + ++ G G++
Sbjct: 898 EEGEGEGEEEGEGEGEE 914
Score = 35.0 bits (79), Expect = 0.12
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 11/123 (8%)
Query: 280 KEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFK-G 338
+E G+ ++ G + E E EGE E+E ++ E++ E + + +G + G
Sbjct: 960 EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEG 1019
Query: 339 KGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQ 398
+ +G + G G+G+ + ++E +E ++ G +R REE ++EE K
Sbjct: 1020 EVEGEVEGEEGEGEGEEE--------EGEEEGEEREKEGEGEENRRNREEEEEEE--GKY 1069
Query: 399 QKT 401
Q+T
Sbjct: 1070 QET 1072
Score = 34.3 bits (77), Expect = 0.21
Identities = 44/223 (19%), Positives = 96/223 (43%), Gaps = 26/223 (11%)
Query: 191 KKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLH 250
++ E +K+ + + + ++E + + EE+ E + E++ G ++ G++++ +
Sbjct: 771 EEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVE-GGEVEEGKGEREEE 829
Query: 251 ILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEV 310
GE + + +EG + +E G+ K G + E E EGE
Sbjct: 830 ---EEEGEGEEEEGEGEEEEG------EGEEEEGEGKGEEEG--EEGEGEEEGEEGEGEG 878
Query: 311 EKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQ------PGSGKGKVQFQGKKTKF 364
E+E E + E + + +G +G+G+G + + G GKG + +G++ +
Sbjct: 879 EEE------EGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKG--EEEGEEGEG 930
Query: 365 ASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGD 407
++E E + G + E + EE + + E G G+
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Score = 32.3 bits (72), Expect = 0.79
Identities = 24/106 (22%), Positives = 49/106 (46%), Gaps = 5/106 (4%)
Query: 307 EGEVEKEALKKIIED--QQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKV---QFQGKK 361
EGE E+E + E+ + E + + +G +G+GKG + + G G+G+ + +G+
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943
Query: 362 TKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGD 407
+ ++E E + G + E + E + + E G G+
Sbjct: 944 GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGE 989
Score = 32.0 bits (71), Expect = 1.0
Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 14/140 (10%)
Query: 276 KEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRR 335
+E+ +E G+ ++ G + + E E EGE E E E++ E + + +G
Sbjct: 922 EEEGEEGEGEGEE-EEGEGEGEDGEGEGEEEEGEWEGE------EEEGEGEGEEEGEGEG 974
Query: 336 FKGKGKGNKAAQPGSG-------KGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREE 388
+G+G+G + G G +G+ + +G++ +E +E + G + E
Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEG 1034
Query: 389 TDKEEPASKQQKTENGAGDQ 408
++E +++ + G G++
Sbjct: 1035 EEEEGEEEGEEREKEGEGEE 1054
Score = 30.0 bits (66), Expect = 3.9
Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Query: 286 AKDANNGNLQLRNKEVTWEVLE---GEVEK-EALKKIIEDQQE-SLNKWKSKGRRFKG-K 339
A+D+ ++ + E E ++ G EK E L + D+ E S K KS G G +
Sbjct: 593 AEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPE 652
Query: 340 GKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQ 399
G+G+ + GS G +Q ++ + D+ E G + A +E K+ +Q+
Sbjct: 653 GRGDGTCEEGS-SGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQE 711
Query: 400 KTENGAGDQ 408
+ E G Q
Sbjct: 712 QKEREQGHQ 720
Score = 29.3 bits (64), Expect = 6.7
Identities = 43/223 (19%), Positives = 90/223 (40%), Gaps = 20/223 (8%)
Query: 191 KKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLH 250
++ EE ++ + E + +E+E + + EE+ E K EE + G+ + E+
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGE-EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEE-- 881
Query: 251 ILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEV 310
GE G +EG +E+ E G+ + G + + E EGE
Sbjct: 882 ---EGEGE--------GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930
Query: 311 EKEALKKIIEDQ------QESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKF 364
E E + E + +E +W+ + +G+G+ + G+G+ + + + +
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG 990
Query: 365 ASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGD 407
++ +E +E G E ++E + + E G G+
Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE 1033
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/269 (23%), Positives = 115/269 (42%), Gaps = 47/269 (17%)
Query: 72 LSKSKAELMEISEDKTKIRRSPSKPLPEVT------DEYKNDVKNRSVYIKGFPTDATLD 125
L K+ ++ ++S++K ++ + E T D+ K D+ + + +K
Sbjct: 343 LEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVK--------- 393
Query: 126 DIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFK 185
W ++K ++ HK K + + AK+ E + D++ ++
Sbjct: 394 ----WAQNK-----LKAEMDSHKETKDKLKETTTKLTQAKE--EADQIRKNCQDMIKTYQ 442
Query: 186 DDYFAKKNEERKQNKVEAKLRA------KQEQEAKQKLE-EDAEMKSLEEKIGCLLKFSG 238
+ +EE K N+++AKLR KQ QE +LE A++K LE+ F
Sbjct: 443 E------SEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELED---LKRTFKE 493
Query: 239 DLDD-QTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLR 297
+D+ +T R + L ++ D + KE I K + + L K K A+ QL+
Sbjct: 494 GMDELRTLRTKVKCL--EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQ 551
Query: 298 NKEVTWEVLEGEVEKEALKKIIEDQQESL 326
+ E L+ EV E+L +I D Q+ +
Sbjct: 552 RGKQEIENLKEEV--ESLNSLINDLQKDI 578
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 39.3 bits (90), Expect = 0.006
Identities = 45/183 (24%), Positives = 83/183 (45%), Gaps = 26/183 (14%)
Query: 159 DSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLE 218
+S +S + TP + K L+ L ++ K N+E N+ A L++ + +K E
Sbjct: 449 ESSDSLAAEIVTPEIREK---LIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNE 505
Query: 219 EDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEK 278
+ E + + +++ L+ Q+ E+L + G E +L K+K
Sbjct: 506 LETENRLVNQRL---------LEVQSQVEELQKSLQDQGS---------KAEDSVLLKKK 547
Query: 279 AKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKG 338
+E L K +ANN +L+ K E LE +LK IE+ QE+L K + + ++ +
Sbjct: 548 LEEHLEKLHEANN---ELQKKRAIIEDLEPRFNNSSLK--IEELQEALRKKEEEMKQMEE 602
Query: 339 KGK 341
+ K
Sbjct: 603 RYK 605
Score = 30.0 bits (66), Expect = 3.9
Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 16/119 (13%)
Query: 131 LEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLL----ILFKD 186
L D+ Q L ++ H + K S + +ES KK +E G ++ LL ++
Sbjct: 292 LADEAQSLKDEIDVLRHSSDKVS--KLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQ 349
Query: 187 DYFAKKNEERKQNKVEAKLRAKQEQ----------EAKQKLEEDAEMKSLEEKIGCLLK 235
+ + + E RK N ++L + Q E+K+ + D E K L+EK+ L K
Sbjct: 350 NTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQK 408
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,530,247
Number of Sequences: 37866
Number of extensions: 721913
Number of successful extensions: 5774
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 303
Number of HSP's that attempted gapping in prelim test: 4661
Number of HSP's gapped (non-prelim): 1248
length of query: 408
length of database: 18,247,518
effective HSP length: 105
effective length of query: 303
effective length of database: 14,271,588
effective search space: 4324291164
effective search space used: 4324291164
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.