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Search of human proteins with 117320513
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117320513 coiled-coil domain containing 155 [Homo sapiens]
(562 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117320513 coiled-coil domain containing 155 [Homo sapiens] 1117 0.0
gi|169204626 PREDICTED: hypothetical protein [Homo sapiens] 124 3e-28
gi|239750266 PREDICTED: hypothetical protein [Homo sapiens] 124 3e-28
gi|239744574 PREDICTED: hypothetical protein [Homo sapiens] 124 3e-28
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 73 8e-13
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 72 1e-12
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 63 8e-10
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 59 9e-09
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 59 1e-08
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 58 2e-08
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 58 2e-08
gi|45439327 periplakin [Homo sapiens] 58 3e-08
gi|118498356 kinectin 1 isoform a [Homo sapiens] 56 8e-08
gi|118498368 kinectin 1 isoform c [Homo sapiens] 56 8e-08
gi|33620775 kinectin 1 isoform a [Homo sapiens] 56 8e-08
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens] 56 8e-08
gi|154354985 hook homolog 2 isoform 1 [Homo sapiens] 56 8e-08
gi|71061468 centromere protein E [Homo sapiens] 55 1e-07
gi|31982906 cingulin-like 1 [Homo sapiens] 55 1e-07
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 55 2e-07
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 55 2e-07
gi|58530840 desmoplakin isoform I [Homo sapiens] 55 2e-07
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 55 2e-07
gi|81295809 pericentrin [Homo sapiens] 54 3e-07
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 54 3e-07
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 54 3e-07
gi|221139761 zinc finger protein 853 [Homo sapiens] 54 4e-07
gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 ... 54 4e-07
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K... 54 4e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 54 5e-07
>gi|117320513 coiled-coil domain containing 155 [Homo sapiens]
Length = 562
Score = 1117 bits (2889), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MDLPEGPVGGPTAEMYLRERPEEARLGMPVSLEEQILNSTFEACDPQRTGTVAVAQVLAY 60
MDLPEGPVGGPTAEMYLRERPEEARLGMPVSLEEQILNSTFEACDPQRTGTVAVAQVLAY
Sbjct: 1 MDLPEGPVGGPTAEMYLRERPEEARLGMPVSLEEQILNSTFEACDPQRTGTVAVAQVLAY 60
Query: 61 LEAVTGQGPQDARLQTLANSLDPNGEGPKATVDLDTFLVVMRDWIAACQLHGGLELEEET 120
LEAVTGQGPQDARLQTLANSLDPNGEGPKATVDLDTFLVVMRDWIAACQLHGGLELEEET
Sbjct: 61 LEAVTGQGPQDARLQTLANSLDPNGEGPKATVDLDTFLVVMRDWIAACQLHGGLELEEET 120
Query: 121 AFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGEN 180
AFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGEN
Sbjct: 121 AFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGEN 180
Query: 181 AKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNR 240
AKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNR
Sbjct: 181 AKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNR 240
Query: 241 SLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEH 300
SLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEH
Sbjct: 241 SLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEH 300
Query: 301 LICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQL 360
LICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQL
Sbjct: 301 LICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQL 360
Query: 361 RRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQWEEVIHETSEETEFPSEAPA 420
RRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQWEEVIHETSEETEFPSEAPA
Sbjct: 361 RRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQWEEVIHETSEETEFPSEAPA 420
Query: 421 GGQRNFQGEPAHPEEGRKEPSMWLTRREEEEDAESQVTADLPVPLGAPRPGDIPENPPER 480
GGQRNFQGEPAHPEEGRKEPSMWLTRREEEEDAESQVTADLPVPLGAPRPGDIPENPPER
Sbjct: 421 GGQRNFQGEPAHPEEGRKEPSMWLTRREEEEDAESQVTADLPVPLGAPRPGDIPENPPER 480
Query: 481 PARRELQQALVPVMKKLVPVRRRAWGQLCLPPQRLRVTRHPLIPAPVLGLLLLLLLSVLL 540
PARRELQQALVPVMKKLVPVRRRAWGQLCLPPQRLRVTRHPLIPAPVLGLLLLLLLSVLL
Sbjct: 481 PARRELQQALVPVMKKLVPVRRRAWGQLCLPPQRLRVTRHPLIPAPVLGLLLLLLLSVLL 540
Query: 541 LGPSPPPTWPHLQLCYLQPPPV 562
LGPSPPPTWPHLQLCYLQPPPV
Sbjct: 541 LGPSPPPTWPHLQLCYLQPPPV 562
>gi|169204626 PREDICTED: hypothetical protein [Homo sapiens]
Length = 501
Score = 124 bits (310), Expect = 3e-28
Identities = 81/252 (32%), Positives = 133/252 (52%), Gaps = 21/252 (8%)
Query: 33 EEQILNSTFEACDPQRT---------GTVAVAQVLAYLEAVTGQGPQDARLQTLANSLDP 83
+E+ L S F ACD +R G+V VA+++ +L T Q +D+ L+ L N LDP
Sbjct: 213 KEEALTSIFNACDIKRKELICSSFSKGSVGVAKIINFLRQTTSQNSEDSGLEQLWNMLDP 272
Query: 84 NGEGPKATVDLDTFLVVMRDWIAAC-QLHGGLE------LEEETAFQGALTSRQLPSGCP 136
P VDL+TF +M+DW+A C G+ +++ Q + S
Sbjct: 273 EKRDPH--VDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKSDGTMKMST 330
Query: 137 EAEEP--ANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGS 194
+ + + E+ GGE + L+ +DL++ + DL + R+L EN K + ++ET EE +
Sbjct: 331 DITDSTLGSFEALGGETSKGVLE-VSDLIAYVADLHFNKRKLEEENNKFKLALETLEETN 389
Query: 195 ARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQ 254
++L E+ LR Q+ S QA+ + EELE+LK + EEQ ++AQ++Q E E +
Sbjct: 390 SQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENR 449
Query: 255 HLVAEMETLQEE 266
L+ ++ LQEE
Sbjct: 450 ALILKIRILQEE 461
Score = 31.2 bits (69), Expect = 2.6
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 247 RQAEKEQQHLVAEMETLQEENGKLLAERDGVK---KRSQELAMEKDTLKRQLFECEHLIC 303
R+ E+E +ETL+E N +L + ++ K + + M + LK +L E L
Sbjct: 369 RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL---EELKL 425
Query: 304 QRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
+ +++ V Q E R L L+I L+E++S TY+
Sbjct: 426 SMNASEEQKSMIVAQSKQLETENRA----LILKIRILQEEMSDTYQ 467
>gi|239750266 PREDICTED: hypothetical protein [Homo sapiens]
Length = 501
Score = 124 bits (310), Expect = 3e-28
Identities = 81/252 (32%), Positives = 133/252 (52%), Gaps = 21/252 (8%)
Query: 33 EEQILNSTFEACDPQRT---------GTVAVAQVLAYLEAVTGQGPQDARLQTLANSLDP 83
+E+ L S F ACD +R G+V VA+++ +L T Q +D+ L+ L N LDP
Sbjct: 213 KEEALTSIFNACDIKRKELICSSFSKGSVGVAKIINFLRQTTSQNSEDSGLEQLWNMLDP 272
Query: 84 NGEGPKATVDLDTFLVVMRDWIAAC-QLHGGLE------LEEETAFQGALTSRQLPSGCP 136
P VDL+TF +M+DW+A C G+ +++ Q + S
Sbjct: 273 EKRDPH--VDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKSDGTMKMST 330
Query: 137 EAEEP--ANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGS 194
+ + + E+ GGE + L+ +DL++ + DL + R+L EN K + ++ET EE +
Sbjct: 331 DITDSTLGSFEALGGETSKGVLE-VSDLIAYVADLHFNKRKLEEENNKFKLALETLEETN 389
Query: 195 ARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQ 254
++L E+ LR Q+ S QA+ + EELE+LK + EEQ ++AQ++Q E E +
Sbjct: 390 SQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENR 449
Query: 255 HLVAEMETLQEE 266
L+ ++ LQEE
Sbjct: 450 ALILKIRILQEE 461
Score = 31.2 bits (69), Expect = 2.6
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 247 RQAEKEQQHLVAEMETLQEENGKLLAERDGVK---KRSQELAMEKDTLKRQLFECEHLIC 303
R+ E+E +ETL+E N +L + ++ K + + M + LK +L E L
Sbjct: 369 RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL---EELKL 425
Query: 304 QRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
+ +++ V Q E R L L+I L+E++S TY+
Sbjct: 426 SMNASEEQKSMIVAQSKQLETENRA----LILKIRILQEEMSDTYQ 467
>gi|239744574 PREDICTED: hypothetical protein [Homo sapiens]
Length = 501
Score = 124 bits (310), Expect = 3e-28
Identities = 81/252 (32%), Positives = 133/252 (52%), Gaps = 21/252 (8%)
Query: 33 EEQILNSTFEACDPQRT---------GTVAVAQVLAYLEAVTGQGPQDARLQTLANSLDP 83
+E+ L S F ACD +R G+V VA+++ +L T Q +D+ L+ L N LDP
Sbjct: 213 KEEALTSIFNACDIKRKELICSSFSKGSVGVAKIINFLRQTTSQNSEDSGLEQLWNMLDP 272
Query: 84 NGEGPKATVDLDTFLVVMRDWIAAC-QLHGGLE------LEEETAFQGALTSRQLPSGCP 136
P VDL+TF +M+DW+A C G+ +++ Q + S
Sbjct: 273 EKRDPH--VDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKSDGTMKMST 330
Query: 137 EAEEP--ANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGS 194
+ + + E+ GGE + L+ +DL++ + DL + R+L EN K + ++ET EE +
Sbjct: 331 DITDSTLGSFEALGGETSKGVLE-VSDLIAYVADLHFNKRKLEEENNKFKLALETLEETN 389
Query: 195 ARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQ 254
++L E+ LR Q+ S QA+ + EELE+LK + EEQ ++AQ++Q E E +
Sbjct: 390 SQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENR 449
Query: 255 HLVAEMETLQEE 266
L+ ++ LQEE
Sbjct: 450 ALILKIRILQEE 461
Score = 31.2 bits (69), Expect = 2.6
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 247 RQAEKEQQHLVAEMETLQEENGKLLAERDGVK---KRSQELAMEKDTLKRQLFECEHLIC 303
R+ E+E +ETL+E N +L + ++ K + + M + LK +L E L
Sbjct: 369 RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL---EELKL 425
Query: 304 QRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
+ +++ V Q E R L L+I L+E++S TY+
Sbjct: 426 SMNASEEQKSMIVAQSKQLETENRA----LILKIRILQEEMSDTYQ 467
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 72.8 bits (177), Expect = 8e-13
Identities = 83/315 (26%), Positives = 144/315 (45%), Gaps = 47/315 (14%)
Query: 144 LESFGGEDPRPELQATADLLSS----LEDLELSNRRLVGENAKLQRSMETAEEGSARLGE 199
LE+ E + +L+ +LL + E LE+S + L EN +LQ+++E + + +L
Sbjct: 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 200 EILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAE 259
E+ L + + Q+ L+ K + LE L+ +SLE++ L +Q EKE + L +
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Query: 260 ME----TLQEEN---------GKLLAERDGVKKRS----QELAME-KDTLKRQLFECEHL 301
E TL+E N K L++ G+ K S +EL E K+ +KR + + L
Sbjct: 845 AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTL 904
Query: 302 ICQRDTILSERTR------DVESLAQTLEEYRVTTQEL-----------RLEISRLEEQL 344
+ R+ ++SE+ + D+E L LE+ + + L +L S+LE L
Sbjct: 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTL 964
Query: 345 SQTYEGPDELPEGAQLR---RVGWTELLPPSLGL---EIEAIRQKQ-EVATADLSNPLCG 397
++ E +E + R + + L L EA++Q+Q E S P+ G
Sbjct: 965 KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISG 1024
Query: 398 V-WQWEEVIHETSEE 411
+WE ET+ E
Sbjct: 1025 EDNKWERESQETTRE 1039
Score = 53.1 bits (126), Expect = 6e-07
Identities = 53/211 (25%), Positives = 96/211 (45%), Gaps = 21/211 (9%)
Query: 149 GED---PRPELQATADLLS---SLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEIL 202
GED R + T +LL L ++E +N L E L+ ++ E + L +IL
Sbjct: 1024 GEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL 1083
Query: 203 ALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMET 262
AL++Q S Q E+ L+T L+ +N +L +Q+ + L+ + +
Sbjct: 1084 ALQRQTVSLQ----------EQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSS 1133
Query: 263 LQEENGKLLAERDGVKKRSQELAMEKDTL----KRQLFECEHLICQRDTILSERTRDVES 318
L+ EN ++ ER+ +K L + + L +RQ E E LI + T+ S +++E
Sbjct: 1134 LENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAH-KNLEV 1192
Query: 319 LAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
+ LE+ + + ++ LE+ L E
Sbjct: 1193 EHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1223
Score = 45.4 bits (106), Expect = 1e-04
Identities = 55/212 (25%), Positives = 88/212 (41%), Gaps = 31/212 (14%)
Query: 224 ELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQE 283
EL D K R L ++ Q ++E + + E++ LQ+EN LL++ + E
Sbjct: 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDE 311
Query: 284 LAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQ 343
L D L+ + + L + ER D+E +EE + Q L + LE+Q
Sbjct: 312 L----DALREKAVRVDKLESEVSRY-KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Query: 344 LSQTYEGPDEL----PEGAQLR-------------RVGWTELLPPSLGLEIEAIRQKQEV 386
L T D+L E QL+ R EL+ ++ LE + QKQ
Sbjct: 367 LEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE---MAQKQ-- 421
Query: 387 ATADLSNPLCGVWQWEEVIHETSEETEFPSEA 418
+ L W+ E+ I TSE +E P ++
Sbjct: 422 ---SMDESLHLGWELEQ-ISRTSELSEAPQKS 449
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 14/157 (8%)
Query: 167 EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELE 226
E + S+ + GE+ K +R + ++ + ++ + + ++T QA E +
Sbjct: 1013 ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN-NATLQA---------EKQ 1062
Query: 227 DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAM 286
LKT + LE QN +L AQ +++ L + TLQ +N KL E + +S L
Sbjct: 1063 ALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMN 1122
Query: 287 EKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTL 323
+ L Q E+ + ++++ ER D++SL +L
Sbjct: 1123 QNAQLLIQQSSLEN---ENESVIKER-EDLKSLYDSL 1155
Score = 42.4 bits (98), Expect = 0.001
Identities = 61/266 (22%), Positives = 112/266 (42%), Gaps = 22/266 (8%)
Query: 162 LLSSLEDLELSNRRLVGENAKLQRSMETAE--EGSARLGEEILALRKQLHSTQQALQFAK 219
L S+ ++LE+ +R L +L + E E ++ +E + L + H T A ++ K
Sbjct: 1183 LKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAA-EYKK 1241
Query: 220 AMDEELEDLKTLARSLEE------QNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAE 273
E T ++ L+E +++L + ++ EQ L AE L+E+ +L
Sbjct: 1242 LCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDIT 1301
Query: 274 RDGVKKRSQELAMEKDTLKRQ----LFECEHLICQRDTILSERTRDVESLAQTLEEYRVT 329
+ + + L+ K L+ + L + + L+ Q T+L + + +Y
Sbjct: 1302 STKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDK 1361
Query: 330 TQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSL---GLEIEAIRQKQEV 386
ELR + +LEE++ Y+ D P RR W L L +I RQK
Sbjct: 1362 LNELRRQKEKLEEKIMDQYKFYDPSP---PRRRGNWITLKMRKLIKSKKDINRERQKSLT 1418
Query: 387 ATADLSNPLCGVWQWEEVIHETSEET 412
T S+ G Q + H+ S+++
Sbjct: 1419 LTPTRSDSSEGFLQ---LPHQDSQDS 1441
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/214 (23%), Positives = 96/214 (44%), Gaps = 34/214 (15%)
Query: 164 SSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDE 223
S L +E R++ E + E AEE L E+ L K+ Q+ + K E
Sbjct: 601 SKLSKIEFEKRQIKKELEHYKEKGERAEE----LENELHHLEKENELLQKKITNLKITCE 656
Query: 224 ELEDLKTLARSLEEQNRSLLAQARQAEK---EQQHLVAEMETLQEENGKLLAERDGVKK- 279
++E +LE++N L + R+ +K ++L ++E+L++EN +L E +++
Sbjct: 657 KIE-------ALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709
Query: 280 ----------------RSQELAMEKDTLKRQLFECEHLICQRDTI-LSERTRDVES--LA 320
++EL EK+ LK+ L + + + + +S + D+E+ L
Sbjct: 710 VESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ 769
Query: 321 QTLEEYRVTTQELRLEISRLEEQLSQTYEGPDEL 354
+TLE Q+L E+ LE + + +EL
Sbjct: 770 KTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/215 (24%), Positives = 90/215 (41%), Gaps = 39/215 (18%)
Query: 161 DLLSSLEDLELSNRRLVGENAKL----------QRSMETAEEGSAR---LGEEILALRKQ 207
D LE +E+ +RL EN L + ++ E + R L E+ +++
Sbjct: 276 DCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKER 335
Query: 208 LHSTQQALQFAKAMDEELE-------DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEM 260
LH ++F KA EEL+ + KT+ E R+ + + EKE L A++
Sbjct: 336 LHD----IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL 391
Query: 261 ETLQEENGKLLAERDGVKKRSQELAMEKDTL----KRQLFECEHLICQRDTILSERTRDV 316
++ ERD +K+ +EL E TL K+ + E HL + + I RT ++
Sbjct: 392 HDME-------MERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQI--SRTSEL 442
Query: 317 ESLAQTL--EEYRVTTQELRLEISRLEEQLSQTYE 349
Q E T L++ + L++T E
Sbjct: 443 SEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 477
Score = 34.7 bits (78), Expect = 0.24
Identities = 40/196 (20%), Positives = 91/196 (46%), Gaps = 26/196 (13%)
Query: 162 LLSSLEDLELSN-------RRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQA 214
L + L D+E+ L+ EN L+ + + + + S LG E+ +Q+ T +
Sbjct: 387 LKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWEL----EQISRTSEL 442
Query: 215 LQFA-KAMDEELEDLKTLAR--SLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLL 271
+ K++ E+ +L T +R LE +N+SL K + L +++++ K+L
Sbjct: 443 SEAPQKSLGHEVNEL-TSSRLLKLEMENQSLT-------KTVEELRTTVDSVEGNASKIL 494
Query: 272 AERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQ 331
++K +Q L+ + + L+ ++ + + + + + ++ L +T+E R ++
Sbjct: 495 K----MEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
Query: 332 ELRLEISRLEEQLSQT 347
+ + E L+QT
Sbjct: 551 RQIKILEQENEHLNQT 566
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 72.4 bits (176), Expect = 1e-12
Identities = 83/316 (26%), Positives = 144/316 (45%), Gaps = 48/316 (15%)
Query: 144 LESFGGEDPRPELQATADLLSS----LEDLELSNRRLVGENAKLQRSMETAEEGSARLGE 199
LE+ E + +L+ +LL + E LE+S + L EN +LQ+++E + + +L
Sbjct: 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 200 EILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAE 259
E+ L + + Q+ L+ K + LE L+ +SLE++ L +Q EKE + L +
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Query: 260 ME----TLQEEN---------GKLLAERDGVKKRS----QELAME-KDTLKRQLFECEHL 301
E TL+E N K L++ G+ K S +EL E K+ +KR + + L
Sbjct: 845 AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTL 904
Query: 302 ICQRDTILSERTR------DVESLAQTLEEYRVTTQEL------------RLEISRLEEQ 343
+ R+ ++SE+ + D+E L LE+ + + L +L S+LE
Sbjct: 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLEST 964
Query: 344 LSQTYEGPDELPEGAQLR---RVGWTELLPPSLGL---EIEAIRQKQ-EVATADLSNPLC 396
L ++ E +E + R + + L L EA++Q+Q E S P+
Sbjct: 965 LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPIS 1024
Query: 397 GV-WQWEEVIHETSEE 411
G +WE ET+ E
Sbjct: 1025 GEDNKWERESQETTRE 1040
Score = 53.1 bits (126), Expect = 6e-07
Identities = 53/211 (25%), Positives = 96/211 (45%), Gaps = 21/211 (9%)
Query: 149 GED---PRPELQATADLLS---SLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEIL 202
GED R + T +LL L ++E +N L E L+ ++ E + L +IL
Sbjct: 1025 GEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL 1084
Query: 203 ALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMET 262
AL++Q S Q E+ L+T L+ +N +L +Q+ + L+ + +
Sbjct: 1085 ALQRQTVSLQ----------EQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSS 1134
Query: 263 LQEENGKLLAERDGVKKRSQELAMEKDTL----KRQLFECEHLICQRDTILSERTRDVES 318
L+ EN ++ ER+ +K L + + L +RQ E E LI + T+ S +++E
Sbjct: 1135 LENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAH-KNLEV 1193
Query: 319 LAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
+ LE+ + + ++ LE+ L E
Sbjct: 1194 EHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1224
Score = 45.4 bits (106), Expect = 1e-04
Identities = 55/212 (25%), Positives = 88/212 (41%), Gaps = 31/212 (14%)
Query: 224 ELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQE 283
EL D K R L ++ Q ++E + + E++ LQ+EN LL++ + E
Sbjct: 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDE 311
Query: 284 LAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQ 343
L D L+ + + L + ER D+E +EE + Q L + LE+Q
Sbjct: 312 L----DALREKAVRVDKLESEVSRY-KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Query: 344 LSQTYEGPDEL----PEGAQLR-------------RVGWTELLPPSLGLEIEAIRQKQEV 386
L T D+L E QL+ R EL+ ++ LE + QKQ
Sbjct: 367 LEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE---MAQKQ-- 421
Query: 387 ATADLSNPLCGVWQWEEVIHETSEETEFPSEA 418
+ L W+ E+ I TSE +E P ++
Sbjct: 422 ---SMDESLHLGWELEQ-ISRTSELSEAPQKS 449
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 14/157 (8%)
Query: 167 EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELE 226
E + S+ + GE+ K +R + ++ + ++ + + ++T QA E +
Sbjct: 1014 ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN-NATLQA---------EKQ 1063
Query: 227 DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAM 286
LKT + LE QN +L AQ +++ L + TLQ +N KL E + +S L
Sbjct: 1064 ALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMN 1123
Query: 287 EKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTL 323
+ L Q E+ + ++++ ER D++SL +L
Sbjct: 1124 QNAQLLIQQSSLEN---ENESVIKER-EDLKSLYDSL 1156
Score = 42.4 bits (98), Expect = 0.001
Identities = 61/266 (22%), Positives = 112/266 (42%), Gaps = 22/266 (8%)
Query: 162 LLSSLEDLELSNRRLVGENAKLQRSMETAE--EGSARLGEEILALRKQLHSTQQALQFAK 219
L S+ ++LE+ +R L +L + E E ++ +E + L + H T A ++ K
Sbjct: 1184 LKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAA-EYKK 1242
Query: 220 AMDEELEDLKTLARSLEE------QNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAE 273
E T ++ L+E +++L + ++ EQ L AE L+E+ +L
Sbjct: 1243 LCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDIT 1302
Query: 274 RDGVKKRSQELAMEKDTLKRQ----LFECEHLICQRDTILSERTRDVESLAQTLEEYRVT 329
+ + + L+ K L+ + L + + L+ Q T+L + + +Y
Sbjct: 1303 STKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDK 1362
Query: 330 TQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSL---GLEIEAIRQKQEV 386
ELR + +LEE++ Y+ D P RR W L L +I RQK
Sbjct: 1363 LNELRRQKEKLEEKIMDQYKFYDPSP---PRRRGNWITLKMRKLIKSKKDINRERQKSLT 1419
Query: 387 ATADLSNPLCGVWQWEEVIHETSEET 412
T S+ G Q + H+ S+++
Sbjct: 1420 LTPTRSDSSEGFLQ---LPHQDSQDS 1442
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/214 (23%), Positives = 96/214 (44%), Gaps = 34/214 (15%)
Query: 164 SSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDE 223
S L +E R++ E + E AEE L E+ L K+ Q+ + K E
Sbjct: 601 SKLSKIEFEKRQIKKELEHYKEKGERAEE----LENELHHLEKENELLQKKITNLKITCE 656
Query: 224 ELEDLKTLARSLEEQNRSLLAQARQAEK---EQQHLVAEMETLQEENGKLLAERDGVKK- 279
++E +LE++N L + R+ +K ++L ++E+L++EN +L E +++
Sbjct: 657 KIE-------ALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709
Query: 280 ----------------RSQELAMEKDTLKRQLFECEHLICQRDTI-LSERTRDVES--LA 320
++EL EK+ LK+ L + + + + +S + D+E+ L
Sbjct: 710 VESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ 769
Query: 321 QTLEEYRVTTQELRLEISRLEEQLSQTYEGPDEL 354
+TLE Q+L E+ LE + + +EL
Sbjct: 770 KTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/215 (24%), Positives = 90/215 (41%), Gaps = 39/215 (18%)
Query: 161 DLLSSLEDLELSNRRLVGENAKL----------QRSMETAEEGSAR---LGEEILALRKQ 207
D LE +E+ +RL EN L + ++ E + R L E+ +++
Sbjct: 276 DCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKER 335
Query: 208 LHSTQQALQFAKAMDEELE-------DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEM 260
LH ++F KA EEL+ + KT+ E R+ + + EKE L A++
Sbjct: 336 LHD----IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL 391
Query: 261 ETLQEENGKLLAERDGVKKRSQELAMEKDTL----KRQLFECEHLICQRDTILSERTRDV 316
++ ERD +K+ +EL E TL K+ + E HL + + I RT ++
Sbjct: 392 HDME-------MERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQI--SRTSEL 442
Query: 317 ESLAQTL--EEYRVTTQELRLEISRLEEQLSQTYE 349
Q E T L++ + L++T E
Sbjct: 443 SEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 477
Score = 34.7 bits (78), Expect = 0.24
Identities = 40/196 (20%), Positives = 91/196 (46%), Gaps = 26/196 (13%)
Query: 162 LLSSLEDLELSN-------RRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQA 214
L + L D+E+ L+ EN L+ + + + + S LG E+ +Q+ T +
Sbjct: 387 LKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWEL----EQISRTSEL 442
Query: 215 LQFA-KAMDEELEDLKTLAR--SLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLL 271
+ K++ E+ +L T +R LE +N+SL K + L +++++ K+L
Sbjct: 443 SEAPQKSLGHEVNEL-TSSRLLKLEMENQSLT-------KTVEELRTTVDSVEGNASKIL 494
Query: 272 AERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQ 331
++K +Q L+ + + L+ ++ + + + + + ++ L +T+E R ++
Sbjct: 495 K----MEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
Query: 332 ELRLEISRLEEQLSQT 347
+ + E L+QT
Sbjct: 551 RQIKILEQENEHLNQT 566
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 62.8 bits (151), Expect = 8e-10
Identities = 64/245 (26%), Positives = 105/245 (42%), Gaps = 15/245 (6%)
Query: 114 LELEEETAFQ-GALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLEDLELS 172
LE E+E A Q GA R+L + E+ S ++ ++ +L L
Sbjct: 643 LEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKE-------LVEVREALSRATLQ 695
Query: 173 NRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELE----DL 228
L E A++ ++ AE G L + LR + S Q +L A++E L DL
Sbjct: 696 RDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDL 755
Query: 229 KTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEK 288
L LEE+ +L + RQAE+E E E L+E + R G++ + +
Sbjct: 756 NRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQ 815
Query: 289 DTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQ---ELRLEISRLEEQLS 345
+ L++QL H Q L++ +R + Q LE+ R Q E +R +E L+
Sbjct: 816 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALA 875
Query: 346 QTYEG 350
+ + G
Sbjct: 876 KEHAG 880
Score = 50.1 bits (118), Expect = 5e-06
Identities = 70/281 (24%), Positives = 129/281 (45%), Gaps = 29/281 (10%)
Query: 109 QLHGGLELEEETAFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLED 168
+L+G L EE+ +GAL R G EA ++ D LQ L + D
Sbjct: 1709 RLNGALAKVEES--EGAL--RDKVRGLTEALAQSSASLNSTRDKNLHLQKA--LTACEHD 1762
Query: 169 LELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDL 228
++ RL ++++ A + S+ LGE++ LR ++ + LQ +A + +L+ L
Sbjct: 1763 RQVLQERLDAA----RQALSEARKQSSSLGEQVQTLRGEVADLE--LQRVEA-EGQLQQL 1815
Query: 229 KTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEK 288
+ + R +E + L ++ + E++ L + +LQ +L AE+ V++ + L ++
Sbjct: 1816 REVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDR 1875
Query: 289 DTLKRQL--FECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQ--- 343
L+R L E E L DT+ + + L +TL + E + +I +LE Q
Sbjct: 1876 VALRRTLDKVEREKLRSHEDTV--RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVV 1933
Query: 344 LSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQ 384
L Q++ P +L AQ +++ L E+E +R Q
Sbjct: 1934 LEQSH-SPAQLEVDAQQQQL--------ELQQEVERLRSAQ 1965
Score = 48.9 bits (115), Expect = 1e-05
Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 23/207 (11%)
Query: 149 GEDPRPELQATADLLSSLEDLELSNRRLVGENAK--LQRSMETAEEGSARLGEEILALRK 206
G + E +AT ++ E L RL E A+ L+ S+ AE+ L +++ LR
Sbjct: 771 GRQRQAEQEAT---VAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRH 827
Query: 207 QLHSTQQAL-QFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAE---KEQQHLVAEMET 262
+ Q+ L Q ++ + ++L+ R + Q +L AR+ E KE L ++
Sbjct: 828 ERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVA 887
Query: 263 LQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQT 322
+ E G+ L+E + L +EK+ L+ LFE + + Q L R +E+ Q
Sbjct: 888 AERE-GRTLSEE------ATRLRLEKEALEGSLFEVQRQLAQ----LEARREQLEAEGQA 936
Query: 323 LEEYRVTTQELRLEISRLEEQLSQTYE 349
L + + L E++ L +Q+ T E
Sbjct: 937 L---LLAKETLTGELAGLRQQIIATQE 960
Score = 48.9 bits (115), Expect = 1e-05
Identities = 76/295 (25%), Positives = 123/295 (41%), Gaps = 38/295 (12%)
Query: 102 RDWIAACQLHGGLELEEETAFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATAD 161
R+ A + H GL ++ A + T + + +E F + +L+A +
Sbjct: 869 REKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 928
Query: 162 LLSSL-EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILA--LRKQLHSTQQALQFA 218
L + + L L+ L GE A L++ + +E A L +E++A L + Q +L+
Sbjct: 929 QLEAEGQALLLAKETLTGELAGLRQQIIATQE-KASLDKELMAQKLVQAEREAQASLREQ 987
Query: 219 KAMDEELEDLKTLARSLEEQNRSLLAQARQAE----KEQQHLV----AEMETLQEENGKL 270
+A EE DL+ L R E R L A+ Q + +EQ+ L+ AE E L EE L
Sbjct: 988 RAAHEE--DLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAAL 1045
Query: 271 LAERD-----GVKKRSQELAM---EKDTLKRQLFECEHLICQRDTILSERTRDVES---- 318
ERD ++ Q L++ EK L +L H + + + RD +S
Sbjct: 1046 QQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQ 1105
Query: 319 -------LAQTLEEYRVTTQELRL----EISRLEEQLSQTYEGPDE-LPEGAQLR 361
L L + R +E E+ RL+EQ + D L E +LR
Sbjct: 1106 DRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELR 1160
Score = 48.1 bits (113), Expect = 2e-05
Identities = 107/498 (21%), Positives = 191/498 (38%), Gaps = 66/498 (13%)
Query: 70 QDARLQTLANSLDPNGEGPKATVDLDTFLVVMRDWIAACQLHGGLELEEET--AFQGALT 127
+ RLQ A +GEG + T+ D V+ D + QL G + + + +G L+
Sbjct: 431 ESLRLQEQAALETEDGEGLQQTLR-DLAQAVLSDSESGVQLSGSERTADASNGSLRG-LS 488
Query: 128 SRQLPSGCPEAEEPANLESFGGEDPRPELQATADLL-SSLEDLELSNRRLVGENAKLQRS 186
++ PS + G P +T L+ S+L +L + + G Q
Sbjct: 489 GQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDL 548
Query: 187 METAEEGSARLGEEILALRKQLH----STQQALQFAKAMDEELEDLKTLARSLEEQNRSL 242
+ T + + E AL +QL T A+Q + E++ L++ L + +L
Sbjct: 549 LGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNL 608
Query: 243 LAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVK---------------------KRS 281
+ A+++ + L E E LQ +L +RD ++ ++
Sbjct: 609 AHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQL 668
Query: 282 QELAMEKDTLKRQLFECEHLI----CQRDTILSERTRDVESLAQT---LEEYRVTTQELR 334
++L ++ L ++L E + QRD + +E+ E+L + E ++ +LR
Sbjct: 669 EQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLR 728
Query: 335 LEISRLEEQLSQTYEGPDELPEG--------AQL-----------RRVGWTELLPPSLGL 375
E + L++ LS+ + L + AQL R+ +
Sbjct: 729 AEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQE 788
Query: 376 EIEAIRQKQEVATADLSNPLCGVWQWEEVIHE----TSEETEFPSEAPAGGQRNFQGEPA 431
+E +R +QEVA L L Q +E + + E E A R G
Sbjct: 789 RLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQ 848
Query: 432 HPEEGRKEPSMW---LTRREEEEDAESQVTADLPVPL-GAPRPGDI--PENPPERPARRE 485
E+ R+E L R E++A ++ A L V L A R G E R +
Sbjct: 849 ELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEA 908
Query: 486 LQQALVPVMKKLVPVRRR 503
L+ +L V ++L + R
Sbjct: 909 LEGSLFEVQRQLAQLEAR 926
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/252 (23%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 156 LQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQL------- 208
L+ +L + L LE + L E + QR + ++EG +E LR+ L
Sbjct: 1153 LREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKER 1212
Query: 209 ----HSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQA-EKEQQHLVAEMETL 263
S ++ K + E LK LA +EQ +LL +AR A KE L ++ +
Sbjct: 1213 EALRRSNEELRSAVKKAESERISLK-LANEDKEQKLALLEEARTAVGKEAGELRTGLQEV 1271
Query: 264 QEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTL 323
+ + E ++++ + L E L R+L E + + + E R+ L Q L
Sbjct: 1272 ERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRL 1331
Query: 324 ----EEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEA 379
V QEL++ +L+EQ + L + R + L + GLE++
Sbjct: 1332 LKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKL 1391
Query: 380 IRQKQEVATADL 391
+ E A L
Sbjct: 1392 EAARAEAAELGL 1403
Score = 39.3 bits (90), Expect = 0.010
Identities = 53/222 (23%), Positives = 90/222 (40%), Gaps = 19/222 (8%)
Query: 179 ENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDE---ELEDLKTLARSL 235
EN LQ+ + E+ A+ E L + ++ + L+ A ++ E ++ + L R
Sbjct: 82 ENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQS 141
Query: 236 EEQNRSLLAQA----RQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTL 291
E R L + R+ + Q+ + + +Q GK+L + + Q+L L
Sbjct: 142 VELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGEL 201
Query: 292 KRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGP 351
++Q RDT E ++D+ES LEE + + L + L EQL Q
Sbjct: 202 EQQRL--------RDT---EHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSAN 250
Query: 352 DELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATADLSN 393
L E + WT L A R+++E A SN
Sbjct: 251 QALSEDIRKVTNDWTR-CRKELEHREAAWRREEESFNAYFSN 291
Score = 35.8 bits (81), Expect = 0.11
Identities = 40/171 (23%), Positives = 75/171 (43%), Gaps = 23/171 (13%)
Query: 191 EEGSARLGEEILALRKQLHSTQQALQFAKAMDE---ELEDLKTLARSLEEQNRSLLAQAR 247
EE +A +E+ L+ +QA K D E E+L+T R LE+ L +
Sbjct: 1125 EEAAAAHAQEVRRLQ------EQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELL 1178
Query: 248 QAEKEQQHLVAEMETLQEENGKL-------LAERDGVKKRSQEL--AMEKDTLKRQLFEC 298
+A+++ + E ++E G+L ER+ +++ ++EL A++K +R +
Sbjct: 1179 EAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKL 1238
Query: 299 EHLICQRDTILSERTR-----DVESLAQTLEEYRVTTQELRLEISRLEEQL 344
+ ++ L E R + L L+E + E R E+ L Q+
Sbjct: 1239 ANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQM 1289
Score = 33.5 bits (75), Expect = 0.53
Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 26/205 (12%)
Query: 148 GGEDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQ 207
G ++ ++ +L S+++ E L N ++ + EE +G+E LR
Sbjct: 1208 GAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTG 1267
Query: 208 LHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSL----------LAQARQAEKEQQHLV 257
L +++ A+ EL++L+ + L+ +N L LA +AEKE +
Sbjct: 1268 LQEVERSRLEAR---RELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRR-- 1322
Query: 258 AEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILS-ERTRDV 316
ETL +LL ++ QEL + + L+ Q E E +R + S E R
Sbjct: 1323 ---ETLGLRQ-RLLKGEASLEVMRQELQVAQRKLQEQ--EGEFRTRERRLLGSLEEARGT 1376
Query: 317 ESLAQTLEEYRVTTQELRLEISRLE 341
E Q L+ R EL+LE +R E
Sbjct: 1377 EK--QQLDHAR--GLELKLEAARAE 1397
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 59.3 bits (142), Expect = 9e-09
Identities = 76/320 (23%), Positives = 134/320 (41%), Gaps = 37/320 (11%)
Query: 167 EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELE 226
E L RL + +L+ E E RL E+ LR+Q ++ + + + E E
Sbjct: 199 ERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQ---EERLCEQEERLREHEE 255
Query: 227 DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAM 286
L L EQ L Q + ++++ L + E L+E+ +L + + ++++ + L
Sbjct: 256 RLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCE 315
Query: 287 EKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLE-EYRVTTQELRLEISRLEEQLS 345
+++ L+ Q E +C+++ + + R +E + + LE E R QE LE RL E++
Sbjct: 316 QEERLREQ----EERLCEQEKLPGQE-RLLEEVEKLLEQERRQEEQERLLERERLLEEV- 369
Query: 346 QTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQWEEVI 405
+EL E +LR+ L E+E +R+ + + WE +
Sbjct: 370 ------EELLEQERLRQQD-ERLWQQETLQELERLRELERMLELG----------WEALY 412
Query: 406 HETSEET----EFPSEAPAGGQRNFQGEPAHPEEGRKEPSMWLTRREEEEDAESQVTADL 461
+ +E E +E + Q Q + G +EP R E A ++ A
Sbjct: 413 EQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEP------RGSESAAAARPVAGA 466
Query: 462 PVPLGAPRPGDIPENPPERP 481
PVP GA G P E P
Sbjct: 467 PVPQGAWMCGQAGWTPQEHP 486
Score = 36.2 bits (82), Expect = 0.082
Identities = 67/307 (21%), Positives = 126/307 (41%), Gaps = 47/307 (15%)
Query: 164 SSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILAL-RKQLHSTQQALQFAKAMD 222
++LEDLE + +L +++++ ++L E I +L R + + + +
Sbjct: 82 TTLEDLE-------SQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLG 134
Query: 223 EELEDLKT-LARSLEEQNRSLLAQARQAEKEQQHLVAEMETL------QEENGKLLAERD 275
L LK A L + + ++ Q + E HL E+E++ + EN ++L+ +
Sbjct: 135 RSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN 194
Query: 276 GVKKRSQELAMEKDTLKRQ---LFECEHLICQRDTILSERTRDVESLAQTL--------- 323
+++ + L +++ L+ Q L E E +C+++ L E+ + + L
Sbjct: 195 --RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252
Query: 324 EEYRVTTQELRL--EISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIR 381
E R+ QE RL + RL EQ + +E + L E + R E E
Sbjct: 253 HEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLR-------------EQEERL 299
Query: 382 QKQEVATADLSNPLCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQGEPAHPEEGRKEPS 441
+QE + LC + EE + E E + P + + E +E R+E
Sbjct: 300 CEQEERLREQEERLC---EQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ 356
Query: 442 MWLTRRE 448
L RE
Sbjct: 357 ERLLERE 363
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/205 (24%), Positives = 99/205 (48%), Gaps = 9/205 (4%)
Query: 150 EDPRPELQATADLLSSL----EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALR 205
E + EL+ DLL +L E LELS + + EN +LQ+S+E++ + L E+ L
Sbjct: 734 EREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQTLESELGELE 793
Query: 206 KQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEME---- 261
+ + ++ L+ + + +LE + ++LE++ L + EKE + L ++E
Sbjct: 794 AERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELKDA 853
Query: 262 TLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQ 321
L + KL A + +ELA +D + L E E ++ R + +L +
Sbjct: 854 VLDDSTAKLSAVEKESRALDKELARCRDAAGK-LKELEKDNRDLTKQVTVHARTLTTLRE 912
Query: 322 TLEEYRVTTQELRLEISRLEEQLSQ 346
L ++ +Q+L E+ +L ++L +
Sbjct: 913 DLVLEKLKSQQLSSELDKLSQELEK 937
Score = 52.4 bits (124), Expect = 1e-06
Identities = 58/218 (26%), Positives = 103/218 (47%), Gaps = 35/218 (16%)
Query: 165 SLEDLELSNRRLVGENAKLQRSMETAEEGSAR----LGEEILALRKQLHSTQQALQF--- 217
S +DLE + L+ E +LQ MET + AR L +E L + + S ++ Q
Sbjct: 523 SNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAMWSLRERSQVSSE 582
Query: 218 AKAMDEELEDLKTLARSLEEQNRSL-------------LAQARQAEKEQQHLVAEMETLQ 264
A+ D E E+ K L +++ E N L L QA++ + + L E++ LQ
Sbjct: 583 ARMKDVEKEN-KALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERAEKLERELQRLQ 641
Query: 265 EENGKL----------LAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTR 314
EENG+L + + ++ SQ L +E TL++ L +++ Q + + + +
Sbjct: 642 EENGRLARKVTSLETATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQ 701
Query: 315 -DVES--LAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
D E+ L + +E R T+ +L ++ R +QL + E
Sbjct: 702 LDAENLELRRLVETMRFTSTKL-AQMERENQQLEREKE 738
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/217 (23%), Positives = 100/217 (46%), Gaps = 20/217 (9%)
Query: 153 RPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGE---EILALRKQLH 209
R L ++ LE LE N++L EN +L+R +ET S +L + E L ++
Sbjct: 679 RKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKE 738
Query: 210 STQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGK 269
++ + KA+ ++ E L+ +S+ +N L +Q+ + H + +TL+ E G+
Sbjct: 739 ELRKNVDLLKALGKKSERLELSYQSVSAENLRL----QQSLESSSH---KTQTLESELGE 791
Query: 270 LLAERDGVKKRSQELAMEKDTLK-----RQLFECEHLICQRDTILSERT-----RDVESL 319
L AER +++ + L + L+ R+ E E ++D L E+ + VE
Sbjct: 792 LEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELK 851
Query: 320 AQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPE 356
L++ + E L+++L++ + +L E
Sbjct: 852 DAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKE 888
Score = 43.1 bits (100), Expect = 7e-04
Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 16/215 (7%)
Query: 169 LELSNRRLVGENAKLQRSMETAEEGSARLGEEILALR----------KQLHSTQQALQFA 218
L+ N L + AKLQ T SA L + L+ + L Q+ L A
Sbjct: 1104 LQEHNTTLQTQTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENESLQRQQEQLTAA 1163
Query: 219 -KAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGV 277
+A+ ++ E L TL + +L+ Q + ++L E + L E +G +L + +
Sbjct: 1164 YEALLQDHEHLGTLHERQSAEYEALIRQHSCLKTLHRNLELEHKELGERHGDMLKRKAEL 1223
Query: 278 KKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTL----EEYRVTTQEL 333
++R + L E++ L+++ + + + E R V L L EE T+EL
Sbjct: 1224 EEREKVLTTEREALQQEQRTNALAMGENQRLRGELDR-VNFLHHQLKGEYEELHAHTKEL 1282
Query: 334 RLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTEL 368
+ ++ + +L++ DEL E Q + T+L
Sbjct: 1283 KTSLNNAQLELNRWQARFDELKEQHQTMDISLTKL 1317
Score = 40.0 bits (92), Expect = 0.006
Identities = 52/231 (22%), Positives = 95/231 (41%), Gaps = 39/231 (16%)
Query: 157 QATADLLSSLE---DLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQ 213
+AT +LL + +LE +N L E L+ ++ E + +IL L+KQ
Sbjct: 1047 EATMELLRVKDRAIELERNNAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQ------ 1100
Query: 214 ALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAE 273
+ + E L+T L+ +N +L +Q+ L A+ LQ + E
Sbjct: 1101 ----SAFLQEHNTTLQTQTAKLQVENSTLSSQSAA-------LTAQYTLLQNHHTAKETE 1149
Query: 274 RDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQEL 333
+ ++++ ++L + L L + EHL T+ ++ + E+L + + + L
Sbjct: 1150 NESLQRQQEQLTAAYEAL---LQDHEHL----GTLHERQSAEYEALIRQHSCLKTLHRNL 1202
Query: 334 RLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQ 384
LE L E+ G L+R E L E EA++Q+Q
Sbjct: 1203 ELEHKELGER------------HGDMLKRKAELEEREKVLTTEREALQQEQ 1241
Score = 39.3 bits (90), Expect = 0.010
Identities = 61/239 (25%), Positives = 97/239 (40%), Gaps = 54/239 (22%)
Query: 162 LLSSLEDLELSN-------RRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQA 214
L S L DLEL L+ EN L+ + + + SA LG E+ L K + +
Sbjct: 390 LKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDAS 449
Query: 215 LQFAKAMDEELEDL-KTLARSLEEQNRSLLAQAR-----------------QAEKEQQHL 256
K+ EL + + LE++N+SL + + + EKE L
Sbjct: 450 ---RKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQL 506
Query: 257 VAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLK-----------RQLFECE----HL 301
++E LQ + + ++ S+EL EK+ L+ RQ+ + E HL
Sbjct: 507 SKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHL 566
Query: 302 ------ICQRDTILSE-RTRDVE----SLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
+ +R + SE R +DVE +L QT+ E +L E +L L Q E
Sbjct: 567 NRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKE 625
Score = 32.3 bits (72), Expect = 1.2
Identities = 37/159 (23%), Positives = 61/159 (38%), Gaps = 8/159 (5%)
Query: 196 RLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQH 255
RL E+ +++LH + F KA EEL + + + L AR +
Sbjct: 327 RLELELTRCKEKLHD----VDFYKARMEELREDNIILIETKAMLEEQLTAARARGDKVHE 382
Query: 256 LVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTL----KRQLFECEHLICQRDTILSE 311
L E L+ + L +RD KKR +EL E L K+ + E HL + + +
Sbjct: 383 LEKENLQLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKN 442
Query: 312 RTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEG 350
S + E L++ + + L T +G
Sbjct: 443 ADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQG 481
Score = 30.8 bits (68), Expect = 3.5
Identities = 31/130 (23%), Positives = 64/130 (49%), Gaps = 11/130 (8%)
Query: 165 SLEDLELSNRRLVGENAKLQRSMETAEEGSARLG---EEILALRKQLHSTQQALQ----- 216
+L+ + +N +GEN +L+ ++ +L EE+ A K+L ++ Q
Sbjct: 1236 ALQQEQRTNALAMGENQRLRGELDRVNFLHHQLKGEYEELHAHTKELKTSLNNAQLELNR 1295
Query: 217 FAKAMDEELEDLKTLARSLEEQNR--SLLAQAR-QAEKEQQHLVAEMETLQEENGKLLAE 273
+ DE E +T+ SL + + LL++ + E+E HL+++++ L ++N LL +
Sbjct: 1296 WQARFDELKEQHQTMDISLTKLDNHCELLSRLKGNLEEENHHLLSQIQLLSQQNQMLLEQ 1355
Query: 274 RDGVKKRSQE 283
K++ E
Sbjct: 1356 NMENKEQYHE 1365
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 58.2 bits (139), Expect = 2e-08
Identities = 56/254 (22%), Positives = 107/254 (42%), Gaps = 25/254 (9%)
Query: 205 RKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQ 264
++Q + + Q + +E+ K R LEEQ R +Q E+EQ+ E +
Sbjct: 375 QQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
Query: 265 EENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLE 324
EE + E++ ++++ +E + + L++QL + L+ + E R E L + L+
Sbjct: 435 EERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLK 494
Query: 325 ---EYRVTTQELRLEISRLEEQLSQTYE---GPDELPEGAQLRRVGWTELLPPSLGLEIE 378
+Y V+ Q R E +E++ Y+ P E P W + +P +
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP--------AWAKEIP-----HLV 541
Query: 379 AIRQKQEVATADLS---NPLCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQGEPAHPEE 435
A++ + TA S P G+ ++E ++ TS E P + + P
Sbjct: 542 AVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQ---NSDPTSENPPLPTRI 598
Query: 436 GRKEPSMWLTRREE 449
+ + S WL + E+
Sbjct: 599 EKFDRSSWLRQEED 612
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 58.2 bits (139), Expect = 2e-08
Identities = 56/254 (22%), Positives = 107/254 (42%), Gaps = 25/254 (9%)
Query: 205 RKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQ 264
++Q + + Q + +E+ K R LEEQ R +Q E+EQ+ E +
Sbjct: 375 QQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
Query: 265 EENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLE 324
EE + E++ ++++ +E + + L++QL + L+ + E R E L + L+
Sbjct: 435 EERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLK 494
Query: 325 ---EYRVTTQELRLEISRLEEQLSQTYE---GPDELPEGAQLRRVGWTELLPPSLGLEIE 378
+Y V+ Q R E +E++ Y+ P E P W + +P +
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP--------AWAKEIP-----HLV 541
Query: 379 AIRQKQEVATADLS---NPLCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQGEPAHPEE 435
A++ + TA S P G+ ++E ++ TS E P + + P
Sbjct: 542 AVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQ---NSDPTSENPPLPTRI 598
Query: 436 GRKEPSMWLTRREE 449
+ + S WL + E+
Sbjct: 599 EKFDRSSWLRQEED 612
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 57.8 bits (138), Expect = 3e-08
Identities = 62/242 (25%), Positives = 110/242 (45%), Gaps = 27/242 (11%)
Query: 114 LELEEETAFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLEDLELSN 173
++LE E A Q +R+ E E E+ P L+A A + D+EL
Sbjct: 1323 VDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEE-EPGLRAEASAFAESIDVEL-- 1379
Query: 174 RRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLAR 233
R++ A+L+R E L +QL ++ Q + + E++ L+
Sbjct: 1380 RQIDKLRAELRRLQRRRTE-----------LERQLEELERERQARREAEREVQRLQQRLA 1428
Query: 234 SLEEQNRSLLAQARQAEKEQQHLVAEMETLQ-EENGKLLAERDGVKKRSQELAMEKDTLK 292
+LE++ A+AR+ Q +V + + Q E+ L + + + R Q L E +TL+
Sbjct: 1429 ALEQEE----AEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEGELETLR 1484
Query: 293 RQLFECEHLICQRDTILSERTR--------DVESLAQTLEEYRVTTQELRLEISRLEEQL 344
R+L E + +LSE + +++ L +LEE + +EL +E+SRLE +L
Sbjct: 1485 RKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARL 1544
Query: 345 SQ 346
S+
Sbjct: 1545 SE 1546
Score = 45.4 bits (106), Expect = 1e-04
Identities = 75/329 (22%), Positives = 133/329 (40%), Gaps = 62/329 (18%)
Query: 155 ELQATADLLSSLE-DLELSNRRLVGENAKLQR---SMETAEEGSARLGEEILALRKQLHS 210
ELQA LL +E +L+ + + ++ Q +E E +LG+ LR+Q+
Sbjct: 661 ELQAQKSLLGEVEQNLQAAKQCSSTLASRFQEHCPDLERQEAEVHKLGQRFNNLRQQVER 720
Query: 211 TQQALQFAKAM--------DEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMET 262
Q+LQ AKA D L+ L ++ S E Q L+Q K Q++L+ E+ +
Sbjct: 721 RAQSLQSAKAAYEHFHRGHDHVLQFLVSIP-SYEPQETDSLSQMETKLKNQKNLLDEIAS 779
Query: 263 LQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQT 322
++E K+ A ++ ++ +E + L R L + E+ R + +S+R R ++S A
Sbjct: 780 REQEVQKICANSQQYQQAVKDYELEAEKL-RSLLDLEN---GRSSHVSKRAR-LQSPATK 834
Query: 323 LEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQ 382
++E E+ + Q Q E + +RQ
Sbjct: 835 VKEEEAALAAKFTEVYAINRQRLQNLE-------------------------FALNLLRQ 869
Query: 383 KQEV----ATADLSNPLCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQGEPAHPEEGRK 438
+ EV T + P GV + ++ E EETE +R + E +E
Sbjct: 870 QPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETE--------RRRQLENEVKSTQE--- 918
Query: 439 EPSMWLTRRE--EEEDAESQVTADLPVPL 465
+W R + +E +V +P P+
Sbjct: 919 --EIWTLRNQGPQESVVRKEVLKKVPDPV 945
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/198 (23%), Positives = 98/198 (49%), Gaps = 11/198 (5%)
Query: 150 EDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEIL---ALRK 206
+DP+ + + A L LE+ + + L GE L+R + E+ A + E+++ +++
Sbjct: 1451 QDPQ-QAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEK--AEVKEKVVLSESVQV 1507
Query: 207 QLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEE 266
+ T+Q +Q K+ LE+ R L+ + L A+ + E E++ L+EE
Sbjct: 1508 EKGDTEQEIQRLKS---SLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREE 1564
Query: 267 NGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEY 326
N KL ER ++ ++ L E + + + ++ D+ + +R + SL + L++
Sbjct: 1565 NHKLQLERQNLQLETRRLQSEINMAATETRDLRNMTV-ADSGTNHDSR-LWSLERELDDL 1622
Query: 327 RVTTQELRLEISRLEEQL 344
+ +++ LEI L+++L
Sbjct: 1623 KRLSKDKDLEIDELQKRL 1640
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/245 (22%), Positives = 103/245 (42%), Gaps = 27/245 (11%)
Query: 116 LEEETAFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPEL-QATADLLSSLEDLELSN- 173
+E+E ++GA QL S E LE+ P+ E+ + T +++ D E+
Sbjct: 1196 VEQERKYRGA--EEQLRSYQSE------LEALRRRGPQVEVKEVTKEVIKYKTDPEMEKE 1247
Query: 174 -RRLVGENAKLQRSMETAEEGSARLGEEILALR------KQLHSTQQALQFAKAMDEELE 226
+RL E R +E + +L +EI AL+ + Q+ LQF + + E
Sbjct: 1248 LQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEE 1307
Query: 227 DLKTLARSLEEQ------NRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKR 280
A+ EEQ R +Q Q ++++ L E + ++ E G++
Sbjct: 1308 VASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAE 1367
Query: 281 SQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRL 340
+ A D RQ+ + + + L R ++E + LE R +E E+ RL
Sbjct: 1368 ASAFAESIDVELRQIDKLRAELRR----LQRRRTELERQLEELERERQARREAEREVQRL 1423
Query: 341 EEQLS 345
+++L+
Sbjct: 1424 QQRLA 1428
Score = 39.7 bits (91), Expect = 0.007
Identities = 64/253 (25%), Positives = 109/253 (43%), Gaps = 37/253 (14%)
Query: 155 ELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLG---EEILAL-RKQLHS 210
+ + A+ L SL DLE V + A+LQ +E A L E+ A+ R++L +
Sbjct: 800 DYELEAEKLRSLLDLENGRSSHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQN 859
Query: 211 TQQALQFAKAMDEELEDLKTLAR----SLEEQNRSLLAQARQAEKEQQHLVAEMETLQEE 266
+ AL + E +TL R S E+ + + + + ++ L E+++ QEE
Sbjct: 860 LEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEE 919
Query: 267 NGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEY 326
L + QE + K+ LK+ D +L E + L +TL E
Sbjct: 920 IWTLR------NQGPQESVVRKEVLKK----------VPDPVLEE---SFQQLQRTLAEE 960
Query: 327 RVTTQELRLEISRLEEQL----SQTYEGPDELPEGAQLR----RVGWTELLPPSLGLEIE 378
+ Q L+ E+ L+ QL +T +G E LR R E+L L E+E
Sbjct: 961 QHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVL--QLREELE 1018
Query: 379 AIRQKQEVATADL 391
A+R+++ A++
Sbjct: 1019 ALRRQKGAREAEV 1031
Score = 37.0 bits (84), Expect = 0.048
Identities = 46/220 (20%), Positives = 95/220 (43%), Gaps = 19/220 (8%)
Query: 138 AEEPANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARL 197
AEE + + E +LQ L + + L+ ++R K + + ++ RL
Sbjct: 1042 AEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRL 1101
Query: 198 GEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLV 257
+E A+ + + ++ L+ K E E + L R E++ A+AR +++E+ L+
Sbjct: 1102 EKE-RAMAEGKITVKEVLKVEKDAATERE-VSDLTRQYEDE----AAKARASQREKTELL 1155
Query: 258 AEMETLQEENGKLLAERD--GVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRD 315
++ L+EEN K++ + + + + E L+ +L E E + L +
Sbjct: 1156 RKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSE 1215
Query: 316 VESLAQTLEEYRV-----------TTQELRLEISRLEEQL 344
+E+L + + V T E+ E+ RL E++
Sbjct: 1216 LEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEI 1255
Score = 35.8 bits (81), Expect = 0.11
Identities = 62/273 (22%), Positives = 113/273 (41%), Gaps = 24/273 (8%)
Query: 129 RQLPSGCPEAE-EPANLESFGGEDPRPELQATADLLSSLEDLELSNRR--------LVGE 179
R++ P+AE E ANL E R A L S +LE RR + E
Sbjct: 1175 REIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKE 1234
Query: 180 NAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQN 239
K + E +E RL EEI+ + + + K + L+D K ++ E
Sbjct: 1235 VIKYKTDPEMEKE-LQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQ 1293
Query: 240 RSLLAQAR-QAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFEC 298
L Q Q ++E L A++ Q++ L ER + +++A +++ L R
Sbjct: 1294 EILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERER---ASQEEQIARKEEELSR----V 1346
Query: 299 EHLICQRDTILSERT----RDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDEL 354
+ + Q++ + E + + A++++ +LR E+ RL+ + ++ +EL
Sbjct: 1347 KERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEEL 1406
Query: 355 PEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVA 387
Q RR E+ L + A+ Q++ A
Sbjct: 1407 ERERQARREAEREV--QRLQQRLAALEQEEAEA 1437
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 56.2 bits (134), Expect = 8e-08
Identities = 50/204 (24%), Positives = 99/204 (48%), Gaps = 16/204 (7%)
Query: 163 LSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMD 222
+ S+E+L L E K+ +T ++ L +EI AL++++ + Q ++
Sbjct: 810 IKSVEEL------LEAELLKVANKEKTVQD----LKQEIKALKEEIGNVQLEKAQQLSIT 859
Query: 223 EELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKK--- 279
++++L+ L + EEQ ++ A + EK+ + ++ LQEEN L A V +
Sbjct: 860 SKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNL 919
Query: 280 RSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISR 339
+ A + + L+ L E E+ + + + +L ER D+ S Q L++ + E +L S+
Sbjct: 920 KEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQ---DENKLFKSQ 976
Query: 340 LEEQLSQTYEGPDELPEGAQLRRV 363
+E+ Q Y+ P +L +V
Sbjct: 977 IEQLKQQNYQQASSFPPHEELLKV 1000
Score = 41.2 bits (95), Expect = 0.003
Identities = 60/314 (19%), Positives = 131/314 (41%), Gaps = 40/314 (12%)
Query: 155 ELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLG---EEILALRKQLHST 211
+LQ + + +E + + ++ KL+ E E G ++ EE+ A+R + S
Sbjct: 716 KLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSL 775
Query: 212 QQALQFAKAMDEE-------LEDLKTLA-------RSLEEQNRSLLAQARQAEKEQQHLV 257
+ +Q KA + +E+LK + +S+EE + L + EK Q L
Sbjct: 776 TKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLK 835
Query: 258 AEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVE 317
E++ L+EE G + E K + + + L+ L E + +L E+ +D+
Sbjct: 836 QEIKALKEEIGNVQLE----KAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Query: 318 SLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEI 377
+ + L++ + + L+ + + + L E + + E++ E+
Sbjct: 892 NTGKWLQDLQEENESLKAHVQEVAQH---------NLKEASSASQFEELEIVLKEKENEL 942
Query: 378 EAIRQKQEVATADLSNPLCGVWQWEEVIHETSEETE-FPSEAPAGGQRNFQGEPAHPEEG 436
+ + + +DLS+ +++ + +E + F S+ Q+N+Q + P
Sbjct: 943 KRLEAMLKERESDLSSK-------TQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP-- 993
Query: 437 RKEPSMWLTRREEE 450
+E ++ RE+E
Sbjct: 994 HEELLKVISEREKE 1007
Score = 32.0 bits (71), Expect = 1.5
Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 9/171 (5%)
Query: 182 KLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKA--MDEELEDLKTLARSLEEQN 239
K Q+ E E A L +E LR + +T L+ ++ +++ +D L L E+
Sbjct: 407 KFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKT 466
Query: 240 RSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECE 299
L + Q + +Q LQE + + ++KR+ E + L+ + E
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 300 HLICQRDTILSERTRDVESLAQTL------EEYRVTTQE-LRLEISRLEEQ 343
+ + + L++ + L Q L E+ RV +E L++++ + EQ
Sbjct: 527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 577
Score = 32.0 bits (71), Expect = 1.5
Identities = 45/239 (18%), Positives = 102/239 (42%), Gaps = 8/239 (3%)
Query: 112 GGLELEEETAFQGALTSRQLPSGCPEAEEP-ANLESFGGEDPRPELQATADLLSSLEDLE 170
G L+ EE + QL EAE ++S+ + A DL S E
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 171 LSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKT 230
+ L ++KL ++ + ++ RL + + + +K+++ + + + E+ E LK
Sbjct: 527 NEVQSL---HSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 231 LARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDT 290
+ Q + + + AE+ + + + + +++ L +ERD + + +EL KD
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEEL---KD- 639
Query: 291 LKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
++ F + + + + +E+ L + + V ++RL +L+ ++S E
Sbjct: 640 IQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME 698
Score = 31.6 bits (70), Expect = 2.0
Identities = 55/244 (22%), Positives = 92/244 (37%), Gaps = 32/244 (13%)
Query: 160 ADLLSSLEDLELSNRRLV-----GENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQA 214
AD + +L LE + V G KLQRS+E E +E KQ+ S+
Sbjct: 1125 ADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSS--- 1181
Query: 215 LQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAER 274
+ ++ELE L++ + +E R E++HL E+E + E + E
Sbjct: 1182 ---FTSSEQELERLRSENKDIENLRR-----------EREHLEMELEKAEMERSTYVTEV 1227
Query: 275 DGVKKRSQELAMEKD----TLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTT 330
+K EL + D RQ E L Q + L++ + + +
Sbjct: 1228 RELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQ 1287
Query: 331 QELRLEISRLEEQLSQT--YEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVAT 388
Q L L S++ + T E D PE + E + SL + ++Q +
Sbjct: 1288 QSLELIQSKIVKAAGDTTVIENSDVSPETESSEK----ETMSVSLNQTVTQLQQLLQAVN 1343
Query: 389 ADLS 392
L+
Sbjct: 1344 QQLT 1347
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 56.2 bits (134), Expect = 8e-08
Identities = 50/204 (24%), Positives = 99/204 (48%), Gaps = 16/204 (7%)
Query: 163 LSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMD 222
+ S+E+L L E K+ +T ++ L +EI AL++++ + Q ++
Sbjct: 810 IKSVEEL------LEAELLKVANKEKTVQD----LKQEIKALKEEIGNVQLEKAQQLSIT 859
Query: 223 EELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKK--- 279
++++L+ L + EEQ ++ A + EK+ + ++ LQEEN L A V +
Sbjct: 860 SKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNL 919
Query: 280 RSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISR 339
+ A + + L+ L E E+ + + + +L ER D+ S Q L++ + E +L S+
Sbjct: 920 KEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQ---DENKLFKSQ 976
Query: 340 LEEQLSQTYEGPDELPEGAQLRRV 363
+E+ Q Y+ P +L +V
Sbjct: 977 IEQLKQQNYQQASSFPPHEELLKV 1000
Score = 41.2 bits (95), Expect = 0.003
Identities = 60/314 (19%), Positives = 131/314 (41%), Gaps = 40/314 (12%)
Query: 155 ELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLG---EEILALRKQLHST 211
+LQ + + +E + + ++ KL+ E E G ++ EE+ A+R + S
Sbjct: 716 KLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSL 775
Query: 212 QQALQFAKAMDEE-------LEDLKTLA-------RSLEEQNRSLLAQARQAEKEQQHLV 257
+ +Q KA + +E+LK + +S+EE + L + EK Q L
Sbjct: 776 TKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLK 835
Query: 258 AEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVE 317
E++ L+EE G + E K + + + L+ L E + +L E+ +D+
Sbjct: 836 QEIKALKEEIGNVQLE----KAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Query: 318 SLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEI 377
+ + L++ + + L+ + + + L E + + E++ E+
Sbjct: 892 NTGKWLQDLQEENESLKAHVQEVAQH---------NLKEASSASQFEELEIVLKEKENEL 942
Query: 378 EAIRQKQEVATADLSNPLCGVWQWEEVIHETSEETE-FPSEAPAGGQRNFQGEPAHPEEG 436
+ + + +DLS+ +++ + +E + F S+ Q+N+Q + P
Sbjct: 943 KRLEAMLKERESDLSSK-------TQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP-- 993
Query: 437 RKEPSMWLTRREEE 450
+E ++ RE+E
Sbjct: 994 HEELLKVISEREKE 1007
Score = 32.0 bits (71), Expect = 1.5
Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 9/171 (5%)
Query: 182 KLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKA--MDEELEDLKTLARSLEEQN 239
K Q+ E E A L +E LR + +T L+ ++ +++ +D L L E+
Sbjct: 407 KFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKT 466
Query: 240 RSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECE 299
L + Q + +Q LQE + + ++KR+ E + L+ + E
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 300 HLICQRDTILSERTRDVESLAQTL------EEYRVTTQE-LRLEISRLEEQ 343
+ + + L++ + L Q L E+ RV +E L++++ + EQ
Sbjct: 527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 577
Score = 32.0 bits (71), Expect = 1.5
Identities = 45/239 (18%), Positives = 102/239 (42%), Gaps = 8/239 (3%)
Query: 112 GGLELEEETAFQGALTSRQLPSGCPEAEEP-ANLESFGGEDPRPELQATADLLSSLEDLE 170
G L+ EE + QL EAE ++S+ + A DL S E
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 171 LSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKT 230
+ L ++KL ++ + ++ RL + + + +K+++ + + + E+ E LK
Sbjct: 527 NEVQSL---HSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 231 LARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDT 290
+ Q + + + AE+ + + + + +++ L +ERD + + +EL KD
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEEL---KD- 639
Query: 291 LKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
++ F + + + + +E+ L + + V ++RL +L+ ++S E
Sbjct: 640 IQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME 698
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 56.2 bits (134), Expect = 8e-08
Identities = 50/204 (24%), Positives = 99/204 (48%), Gaps = 16/204 (7%)
Query: 163 LSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMD 222
+ S+E+L L E K+ +T ++ L +EI AL++++ + Q ++
Sbjct: 810 IKSVEEL------LEAELLKVANKEKTVQD----LKQEIKALKEEIGNVQLEKAQQLSIT 859
Query: 223 EELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKK--- 279
++++L+ L + EEQ ++ A + EK+ + ++ LQEEN L A V +
Sbjct: 860 SKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNL 919
Query: 280 RSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISR 339
+ A + + L+ L E E+ + + + +L ER D+ S Q L++ + E +L S+
Sbjct: 920 KEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQ---DENKLFKSQ 976
Query: 340 LEEQLSQTYEGPDELPEGAQLRRV 363
+E+ Q Y+ P +L +V
Sbjct: 977 IEQLKQQNYQQASSFPPHEELLKV 1000
Score = 41.2 bits (95), Expect = 0.003
Identities = 60/314 (19%), Positives = 131/314 (41%), Gaps = 40/314 (12%)
Query: 155 ELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLG---EEILALRKQLHST 211
+LQ + + +E + + ++ KL+ E E G ++ EE+ A+R + S
Sbjct: 716 KLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSL 775
Query: 212 QQALQFAKAMDEE-------LEDLKTLA-------RSLEEQNRSLLAQARQAEKEQQHLV 257
+ +Q KA + +E+LK + +S+EE + L + EK Q L
Sbjct: 776 TKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLK 835
Query: 258 AEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVE 317
E++ L+EE G + E K + + + L+ L E + +L E+ +D+
Sbjct: 836 QEIKALKEEIGNVQLE----KAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Query: 318 SLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEI 377
+ + L++ + + L+ + + + L E + + E++ E+
Sbjct: 892 NTGKWLQDLQEENESLKAHVQEVAQH---------NLKEASSASQFEELEIVLKEKENEL 942
Query: 378 EAIRQKQEVATADLSNPLCGVWQWEEVIHETSEETE-FPSEAPAGGQRNFQGEPAHPEEG 436
+ + + +DLS+ +++ + +E + F S+ Q+N+Q + P
Sbjct: 943 KRLEAMLKERESDLSSK-------TQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP-- 993
Query: 437 RKEPSMWLTRREEE 450
+E ++ RE+E
Sbjct: 994 HEELLKVISEREKE 1007
Score = 32.0 bits (71), Expect = 1.5
Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 9/171 (5%)
Query: 182 KLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKA--MDEELEDLKTLARSLEEQN 239
K Q+ E E A L +E LR + +T L+ ++ +++ +D L L E+
Sbjct: 407 KFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKT 466
Query: 240 RSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECE 299
L + Q + +Q LQE + + ++KR+ E + L+ + E
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 300 HLICQRDTILSERTRDVESLAQTL------EEYRVTTQE-LRLEISRLEEQ 343
+ + + L++ + L Q L E+ RV +E L++++ + EQ
Sbjct: 527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 577
Score = 32.0 bits (71), Expect = 1.5
Identities = 45/239 (18%), Positives = 102/239 (42%), Gaps = 8/239 (3%)
Query: 112 GGLELEEETAFQGALTSRQLPSGCPEAEEP-ANLESFGGEDPRPELQATADLLSSLEDLE 170
G L+ EE + QL EAE ++S+ + A DL S E
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 171 LSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKT 230
+ L ++KL ++ + ++ RL + + + +K+++ + + + E+ E LK
Sbjct: 527 NEVQSL---HSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 231 LARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDT 290
+ Q + + + AE+ + + + + +++ L +ERD + + +EL KD
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEEL---KD- 639
Query: 291 LKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
++ F + + + + +E+ L + + V ++RL +L+ ++S E
Sbjct: 640 IQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME 698
Score = 31.6 bits (70), Expect = 2.0
Identities = 55/244 (22%), Positives = 92/244 (37%), Gaps = 32/244 (13%)
Query: 160 ADLLSSLEDLELSNRRLV-----GENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQA 214
AD + +L LE + V G KLQRS+E E +E KQ+ S+
Sbjct: 1125 ADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSS--- 1181
Query: 215 LQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAER 274
+ ++ELE L++ + +E R E++HL E+E + E + E
Sbjct: 1182 ---FTSSEQELERLRSENKDIENLRR-----------EREHLEMELEKAEMERSTYVTEV 1227
Query: 275 DGVKKRSQELAMEKD----TLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTT 330
+K EL + D RQ E L Q + L++ + + +
Sbjct: 1228 RELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQ 1287
Query: 331 QELRLEISRLEEQLSQT--YEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVAT 388
Q L L S++ + T E D PE + E + SL + ++Q +
Sbjct: 1288 QSLELIQSKIVKAAGDTTVIENSDVSPETESSEK----ETMSVSLNQTVTQLQQLLQAVN 1343
Query: 389 ADLS 392
L+
Sbjct: 1344 QQLT 1347
>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
Length = 717
Score = 56.2 bits (134), Expect = 8e-08
Identities = 56/211 (26%), Positives = 96/211 (45%), Gaps = 25/211 (11%)
Query: 150 EDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH 209
+D EL+ +++ LE S RR +GE +L+R + EE +A E L +L
Sbjct: 294 KDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELR 353
Query: 210 STQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGK 269
A ++ +LE + + L+ Q + +A + E ++L + E++ +E +
Sbjct: 354 R-------AGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKER 406
Query: 270 LLAERDGVKKRSQELAMEKDTLKRQLFECEHL----ICQRDTILSERTRDVESLAQTL-- 323
LLAERD +++ ++EL C L + Q D L + V++LA +
Sbjct: 407 LLAERDSLREANEEL------------RCAQLQPRGLTQADPSLDPTSTPVDNLAAEILP 454
Query: 324 EEYRVTTQELRLEISRLEEQLSQTYEGPDEL 354
E R T L+LE RL Q + E +EL
Sbjct: 455 AELRETLLRLQLENKRLCRQEAADRERQEEL 485
Score = 39.7 bits (91), Expect = 0.007
Identities = 50/198 (25%), Positives = 82/198 (41%), Gaps = 25/198 (12%)
Query: 157 QATADLLSSLEDLELSNRRLVGENAKLQRSMETAE-EGSARL-GEEILALRKQLHSTQQA 214
Q DL L L + L ENA L+ M E EG+ L +++L L+ QL
Sbjct: 192 QRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQL------ 245
Query: 215 LQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAER 274
E+L++ S E R A+ + E QH + +L +E L E
Sbjct: 246 --------EQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEM 297
Query: 275 DGVKKRSQELAMEKDTL---KRQLFECEHL------ICQRDTILSERTRDVESLAQTLEE 325
D +++ S+ + TL +R+L E L + +R+ +ERTR +E +
Sbjct: 298 DELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGS 357
Query: 326 YRVTTQELRLEISRLEEQ 343
R + R ++ L+ Q
Sbjct: 358 LRAQLEAQRRQVQELQGQ 375
>gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]
Length = 719
Score = 56.2 bits (134), Expect = 8e-08
Identities = 56/211 (26%), Positives = 96/211 (45%), Gaps = 25/211 (11%)
Query: 150 EDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH 209
+D EL+ +++ LE S RR +GE +L+R + EE +A E L +L
Sbjct: 294 KDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELR 353
Query: 210 STQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGK 269
A ++ +LE + + L+ Q + +A + E ++L + E++ +E +
Sbjct: 354 R-------AGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKER 406
Query: 270 LLAERDGVKKRSQELAMEKDTLKRQLFECEHL----ICQRDTILSERTRDVESLAQTL-- 323
LLAERD +++ ++EL C L + Q D L + V++LA +
Sbjct: 407 LLAERDSLREANEEL------------RCAQLQPRGLTQADPSLDPTSTPVDNLAAEILP 454
Query: 324 EEYRVTTQELRLEISRLEEQLSQTYEGPDEL 354
E R T L+LE RL Q + E +EL
Sbjct: 455 AELRETLLRLQLENKRLCRQEAADRERQEEL 485
Score = 39.7 bits (91), Expect = 0.007
Identities = 50/198 (25%), Positives = 82/198 (41%), Gaps = 25/198 (12%)
Query: 157 QATADLLSSLEDLELSNRRLVGENAKLQRSMETAE-EGSARL-GEEILALRKQLHSTQQA 214
Q DL L L + L ENA L+ M E EG+ L +++L L+ QL
Sbjct: 192 QRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLLLQSQL------ 245
Query: 215 LQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAER 274
E+L++ S E R A+ + E QH + +L +E L E
Sbjct: 246 --------EQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEM 297
Query: 275 DGVKKRSQELAMEKDTL---KRQLFECEHL------ICQRDTILSERTRDVESLAQTLEE 325
D +++ S+ + TL +R+L E L + +R+ +ERTR +E +
Sbjct: 298 DELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGS 357
Query: 326 YRVTTQELRLEISRLEEQ 343
R + R ++ L+ Q
Sbjct: 358 LRAQLEAQRRQVQELQGQ 375
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/191 (23%), Positives = 92/191 (48%), Gaps = 10/191 (5%)
Query: 168 DLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQL-HSTQQALQFAKAMDEELE 226
D E + ++ EN ++ + + + + + + AL+ +L + TQ+ + + + E L
Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN 887
Query: 227 DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAM 286
+++ L LE ++ +L + E+E+ + +++ EE L E+D +K+ + L +
Sbjct: 888 EMEQLKEQLENRDSTL----QTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQI 943
Query: 287 EKDTLKRQLFECEHLICQRDTILSERTRD-VESLAQTLEEYRVTTQELRLEISRLEEQLS 345
E+D LK + + ++ DT E+ R+ +ESL Q E ++ E+SR
Sbjct: 944 ERDQLKSDIHDTVNM--NIDT--QEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEE 999
Query: 346 QTYEGPDELPE 356
T E DE +
Sbjct: 1000 NTGETKDEFQQ 1010
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/262 (19%), Positives = 115/262 (43%), Gaps = 18/262 (6%)
Query: 155 ELQATADLLSSL-----EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH 209
E Q T D L + + L + L NAKLQ ++ + +++ L+K ++
Sbjct: 1785 EQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANE----HQLITLKKDVN 1840
Query: 210 STQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGK 269
TQ+ + + + ++++D LE +N +L + + +E + ++ E + L+
Sbjct: 1841 ETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEET 1900
Query: 270 LLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVT 329
L ERD +K+ QE K + E + + + E V+ L + + E +
Sbjct: 1901 LKLERDQLKESLQE-------TKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQ 1953
Query: 330 TQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATA 389
+++ ++ + +++L + + + + QL RV + E+E ++++ E
Sbjct: 1954 ISDIQKDLDKSKDELQKKIQ--ELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNL 2011
Query: 390 DLSNPLCGVWQWEEVIHETSEE 411
+ + +Q + +HE+ EE
Sbjct: 2012 SMQSVRMDNFQLTKKLHESLEE 2033
Score = 53.5 bits (127), Expect = 5e-07
Identities = 51/190 (26%), Positives = 86/190 (45%), Gaps = 14/190 (7%)
Query: 162 LLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAM 221
L ++D + E KL + E L EEI + L +TQ K+
Sbjct: 759 LRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNY---KST 815
Query: 222 DEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRS 281
D+E ++ KTL E++ + +L + + +E +L E + G L E + ++
Sbjct: 816 DQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTE---LSYKT 872
Query: 282 QELAMEKDTLKRQLFECEHLICQRD-------TILSERTRDVESLAQTLEEYRVTTQELR 334
QEL + ++ +L E E L Q + T+ E+T E L QTLEE + TQE +
Sbjct: 873 QELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQE-K 931
Query: 335 LEISRLEEQL 344
++ +L+E L
Sbjct: 932 DDLKQLQESL 941
Score = 47.4 bits (111), Expect = 4e-05
Identities = 50/214 (23%), Positives = 101/214 (47%), Gaps = 41/214 (19%)
Query: 168 DLELSNRRLVGENAKLQRSMETAEEGSARLG-EEILALRKQLHSTQQALQFAKAMDEELE 226
++ ++L N KLQ ++ E + ++I ++++++ +Q + KA D L+
Sbjct: 1506 EISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQ 1565
Query: 227 DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQEL-- 284
+++ + LE NR +++++E Q ++ E E ++ L ERD +K+ ++E+
Sbjct: 1566 SIES--KMLELTNR-----LQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVA 1618
Query: 285 ----AMEKD----------TLKRQLFECEHLICQRDT-------ILSERTRDVESLAQTL 323
+ EK+ + ++ E EHL Q +T I +E R + L + L
Sbjct: 1619 KMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENL 1678
Query: 324 EEYRVTTQE----------LRLEISRLEEQLSQT 347
EE R T+E L++E +L+E L +T
Sbjct: 1679 EEMRSVTKERDDLRSVEETLKVERDQLKENLRET 1712
Score = 47.0 bits (110), Expect = 5e-05
Identities = 62/258 (24%), Positives = 103/258 (39%), Gaps = 24/258 (9%)
Query: 174 RRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLAR 233
RR V E + + E+ +L EEI L H Q+ L K + E E + L
Sbjct: 1255 RRSVSEKTAQIINTQDLEKSHTKLQEEIPVL----HEEQELLPNVKEVSETQETMNELEL 1310
Query: 234 SLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKR 293
E+ + E E+ L + + QEE L ERD +K + L ++ D LK
Sbjct: 1311 LTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKE 1370
Query: 294 QLFEC-----EHLICQRDTI-LSERTRDVESLAQTLEEYRVTTQE-LRLEI------SRL 340
+ E E Q ++ + E+ + + +E+++ LR+EI RL
Sbjct: 1371 HIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRL 1430
Query: 341 EEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQ 400
+E + E + +L+ V +E L I+ I K +L C + +
Sbjct: 1431 QESHDEMKSVAKEKDDLQRLQEVLQSE--SDQLKENIKEIVAKHLETEEELKVAHCCLKE 1488
Query: 401 WEEVIHE-----TSEETE 413
EE I+E + +ETE
Sbjct: 1489 QEETINELRVNLSEKETE 1506
Score = 42.7 bits (99), Expect = 9e-04
Identities = 53/233 (22%), Positives = 101/233 (43%), Gaps = 33/233 (14%)
Query: 183 LQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSL 242
L+ ET + + E + L + LH L+ +++ +E +DL+++ +L+ + L
Sbjct: 1649 LKEQFETQKLNLENIETENIRLTQILHEN---LEEMRSVTKERDDLRSVEETLKVERDQL 1705
Query: 243 LAQARQA-----EKEQQ------HLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTL 291
R+ EK+++ HL ET+ + G + + + + ++L D L
Sbjct: 1706 KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDAL 1765
Query: 292 KRQLFECE--------HLICQRDT------ILSERTRDVESLAQTLEEYRVTTQELRLEI 337
K Q + + HL Q++T I+SE+T + ++ + LE QE E+
Sbjct: 1766 KAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQEL 1825
Query: 338 SRLEEQL----SQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEV 386
E QL E ++ E QL++ + L S LEIE + Q++
Sbjct: 1826 KANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLS-KLEIENLNLAQKL 1877
Score = 40.4 bits (93), Expect = 0.004
Identities = 51/215 (23%), Positives = 96/215 (44%), Gaps = 36/215 (16%)
Query: 156 LQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGE---EILALRKQLHSTQ 212
L+ T L S E++++ ++ E +++R E + +L E EI+A K+ S +
Sbjct: 1572 LELTNRLQESQEEIQI----MIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKE--SQE 1625
Query: 213 QALQFAK--AMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKL 270
+ QF K A++E E + + L+EQ + E E L + EE +
Sbjct: 1626 KEYQFLKMTAVNETQEKMCEIEH-LKEQFETQKLNLENIETENIRLTQILHENLEEMRSV 1684
Query: 271 LAERDGVKKRSQELAMEKDTLKRQLFEC---------------EHLICQRDTI------L 309
ERD ++ + L +E+D LK L E HL ++TI +
Sbjct: 1685 TKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIV 1744
Query: 310 SERTRDVESLAQTLEEYRVTTQELRLEISRLEEQL 344
SE+T ++ ++ + LE + L+ + +++E+L
Sbjct: 1745 SEKTNEISNMQKDLEH---SNDALKAQDLKIQEEL 1776
Score = 37.4 bits (85), Expect = 0.037
Identities = 50/226 (22%), Positives = 89/226 (39%), Gaps = 23/226 (10%)
Query: 143 NLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEIL 202
+LES EDP+ Q D + D + + L EN +L+ M+ ++ +I
Sbjct: 613 SLESI--EDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQ 670
Query: 203 ALRKQLHSTQQ-ALQFAKAMDEELEDLKTLARSLEEQ-------NRSLLAQARQAEKEQQ 254
+ QL + ++ + K + ++ L ++ + N L + +KE
Sbjct: 671 LYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELN 730
Query: 255 HLVAEMETLQEENGKLLAE-----------RDGVKKRSQELAMEKDTLKRQLFECEHLIC 303
V E E L+EE LL+E R ++ +S+EL + + E H
Sbjct: 731 KEVEENEALREE-VILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKES 789
Query: 304 QRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
+ +L E + + LA T Y+ T QE + L Q Y+
Sbjct: 790 RVQGLLEEIGKTKDDLATTQSNYKSTDQEFQ-NFKTLHMDFEQKYK 834
Score = 34.7 bits (78), Expect = 0.24
Identities = 47/221 (21%), Positives = 95/221 (42%), Gaps = 54/221 (24%)
Query: 183 LQRSMETAEEGSARLGEEI---LALRKQLHSTQQALQ-----FAKAMDEELEDLKTLARS 234
L++ ET +++ EE+ L + + T+ Q K D E ++ +TL
Sbjct: 973 LKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTAD 1032
Query: 235 LE-----EQNRSLLAQARQAEKEQQHL---VAEMETLQ---EENGKLLAER--------D 275
++ EQ R + + ++ + QQ L +AE E L+ +EN ++ E D
Sbjct: 1033 VKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGD 1092
Query: 276 GVKKRSQELAMEKD-TLKRQ---------LFECEHLICQRDTILSERTR----------- 314
+KK+ + +A EK+ +K++ L E E + ++ L E+ +
Sbjct: 1093 ELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSE 1152
Query: 315 ------DVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349
++E+L L+ +T + + E L ++L++ YE
Sbjct: 1153 MQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYE 1193
Score = 34.7 bits (78), Expect = 0.24
Identities = 32/144 (22%), Positives = 66/144 (45%), Gaps = 11/144 (7%)
Query: 162 LLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAM 221
LL ED+ +S+++ + E +L++ E + + L K+LH ++L+ + +
Sbjct: 1982 LLRVKEDVNMSHKK-INEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLH---ESLEEIRIV 2037
Query: 222 DEELEDLKTLARSLEEQNRSLLAQARQ--AEKEQQHLVAEMETLQEENGKLLAERDGVKK 279
+E ++L+ + SL+ + +A R+ A Q H V + L + + L E
Sbjct: 2038 AKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTE-----S 2092
Query: 280 RSQELAMEKDTLKRQLFECEHLIC 303
++ + K+ LKR +H C
Sbjct: 2093 LREKCSRIKELLKRYSEMDDHYEC 2116
Score = 33.5 bits (75), Expect = 0.53
Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 10/187 (5%)
Query: 181 AKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNR 240
AK+Q S ++ +E S + E+ K + +Q A+ ++ L++ L+E +
Sbjct: 1377 AKIQES-QSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHD 1435
Query: 241 SLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEH 300
+ + A KE+ L E LQ E+ +L + + E E L E E
Sbjct: 1436 EMKSVA----KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEE 1491
Query: 301 LICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEE-----QLSQTYEGPDELP 355
I + LSE+ ++ ++ + LE Q EI EE Q+S+ E +EL
Sbjct: 1492 TINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELK 1551
Query: 356 EGAQLRR 362
+ + R+
Sbjct: 1552 QFKEHRK 1558
Score = 32.0 bits (71), Expect = 1.5
Identities = 64/322 (19%), Positives = 130/322 (40%), Gaps = 25/322 (7%)
Query: 167 EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILAL---RKQLHSTQQALQFAKAMDE 223
++ E + L +N KL ++ +T + A G ++ K H T +A Q
Sbjct: 2326 KEWEQDLKSLKEKNEKLFKNYQTLKTSLAS-GAQVNPTTQDNKNPHVTSRATQLTTEKIR 2384
Query: 224 ELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAE-RDGVKKRSQ 282
ELE+ A+ S + + ++ + ++A+++ E+ K L + ++ ++
Sbjct: 2385 ELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQD 2444
Query: 283 ELAMEKDTLKRQLFECEHLICQRDTILSERTRDVE---SLAQTLEEYRVTTQELRLEISR 339
++A+ K ++ + + + + D + ++ E S + EY+ L E R
Sbjct: 2445 KVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLR 2504
Query: 340 LEEQLSQT---YEGPDELPEGAQLRRVGWTELL--PPSLGLEIEAIRQKQEVATADLSNP 394
+Q T E D P L G + ++ +L L+ E IR ++E++ N
Sbjct: 2505 RSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNE 2564
Query: 395 LCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQGEPAHP----EEGRKEPSMWLTRREEE 450
+ Q E++ S +E +R + E AH E K P + T +++
Sbjct: 2565 QL-IKQKNELL---SNNQHLSNEVKTWKERTLKRE-AHKQVTCENSPKSPKVTGTASKKK 2619
Query: 451 EDAESQV---TADLPVPLGAPR 469
+ SQ PVP +P+
Sbjct: 2620 QITPSQCKERNLQDPVPKESPK 2641
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 55.5 bits (132), Expect = 1e-07
Identities = 105/463 (22%), Positives = 189/463 (40%), Gaps = 41/463 (8%)
Query: 5 EGPVGGPTAEMYLRERPEEARLGMPVSLEEQILNSTFEACDPQRTGTVAVAQVLAYLEAV 64
E V TA + L+ R A P S ++I TF P + T A +L + +
Sbjct: 494 EEEVKTATATLMLQNR---ATATSPDSGAKKISVKTF----PSASNTQATPDLLKGQQEL 546
Query: 65 TGQGPQDARLQTLANSLDP----NGEGPKATVDLDTFLVVMRDWIAACQLHGGLELEEET 120
T Q ++ Q L N L N + K V+L + AA G + T
Sbjct: 547 TQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQGNNQACNST 606
Query: 121 AFQGALTSRQ--LPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVG 178
+ L ++ L E + LE ++ + E + + ++LE+L + V
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERER---MRANLEELRSQHNEKVE 663
Query: 179 ENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELED-LKTLARSLEE 237
EN+ LQ+ +E +E + EE+ ++ + Q ++ + E+ D L + RS +
Sbjct: 664 ENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDR 723
Query: 238 QNRSLLAQARQAEKEQQHLVAEME----TLQEENGKLLAERDGVKKRSQELAMEKDTLKR 293
+ +L+ + QA+++ Q L+ E L++ +L A + +K+ E D LK
Sbjct: 724 EKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKE 783
Query: 294 QLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDE 353
Q ++ E L R+++ E T++VE LA + + L+E+ + +E
Sbjct: 784 Q-YDAE-LQALRESV-EEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEE 840
Query: 354 LPEG-AQLRRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQWEE-VIHETSEE 411
L AQL+R +IE ++ + A L + Q EE ++H EE
Sbjct: 841 LERRVAQLQR-------------QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEE 887
Query: 412 TEFPS--EAPAGGQRNFQGEPAHPEEGRKEPSMWLTRREEEED 452
E S A QG + + +K+ S L E+++
Sbjct: 888 KEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKE 930
Score = 47.4 bits (111), Expect = 4e-05
Identities = 53/216 (24%), Positives = 95/216 (43%), Gaps = 39/216 (18%)
Query: 160 ADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAK 219
A L +EDL+ G+ AK + +++ E +L E ++ RK+ ++A+ +
Sbjct: 846 AQLQRQIEDLK-------GDEAKAKETLKKYEGEIRQLEEALVHARKE---EKEAVSARR 895
Query: 220 AMDEELE-----------DLKTLARSLEE---QNRSLLAQARQAEKEQQHLVAEMETLQE 265
A++ ELE + K L+ L+E Q L + E E+ HL +E LQ+
Sbjct: 896 ALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQK 955
Query: 266 ENGKLL-AERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLE 324
E ++ A R + +L K+ +R+L E + L E+T + E
Sbjct: 956 EMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQ-------LKEKTLEAE------- 1001
Query: 325 EYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQL 360
+ R+T +++ E+ +EE+L DE QL
Sbjct: 1002 KSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQL 1037
Score = 46.2 bits (108), Expect = 8e-05
Identities = 46/176 (26%), Positives = 72/176 (40%), Gaps = 11/176 (6%)
Query: 179 ENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQA-----LQFAKAMDEELEDLKTLAR 233
+ +L+R E LG+ I L+K++ +A L+ +DE E + R
Sbjct: 928 QKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNR---R 984
Query: 234 SLEEQNRSLLAQARQAEKEQ---QHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDT 290
L E R L + +AEK + + EM ++EE +D + Q L
Sbjct: 985 ELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKD 1044
Query: 291 LKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQ 346
L+ +L HL R ++ + V L LEE R + L ISR EQ+ Q
Sbjct: 1045 LEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQ 1100
Score = 41.2 bits (95), Expect = 0.003
Identities = 43/177 (24%), Positives = 86/177 (48%), Gaps = 23/177 (12%)
Query: 203 ALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRS---LLAQARQAEKEQQHLVAE 259
AL++++ S Q + K ++ +L+ L S+EE ++ L +++ +E++Q
Sbjct: 766 ALKEEVSSHDQEMD--KLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMR 823
Query: 260 METLQEENGKLLAERDGVKKRSQEL-----------AMEKDTLKRQLFECEHLICQRDTI 308
++ LQEEN KL + +++R +L A K+TLK+ E L + +
Sbjct: 824 VKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL---EEAL 880
Query: 309 LSERTRDVESLA--QTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRV 363
+ R + E+++ + LE Q + ++ ++QLS+ + E E QLRR+
Sbjct: 881 VHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKE--QLRRL 935
Score = 38.1 bits (87), Expect = 0.022
Identities = 49/197 (24%), Positives = 88/197 (44%), Gaps = 18/197 (9%)
Query: 150 EDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH 209
+D EL+A + L +D +++ + ++L+ +E S L E I R+Q+
Sbjct: 1043 KDLEYELEAKSHLK---DDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQME 1099
Query: 210 STQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAE----KEQQHLVAEMET-LQ 264
+ L +A ++LE K SLE QN+ L ++ E ++ LV +ME +
Sbjct: 1100 QLRNELLQERAARQDLECDKI---SLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIA 1156
Query: 265 EENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLE 324
E +L +E ++ L + L+R++ E L+ Q D T + L+ L+
Sbjct: 1157 ELEDRLESE----ERDRANLQLSNRRLERKVKE---LVMQVDDEHLSLTDQKDQLSLRLK 1209
Query: 325 EYRVTTQELRLEISRLE 341
+ +E EI RLE
Sbjct: 1210 AMKRQVEEAEEEIDRLE 1226
Score = 37.0 bits (84), Expect = 0.048
Identities = 42/174 (24%), Positives = 80/174 (45%), Gaps = 13/174 (7%)
Query: 170 ELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLK 229
E+ + L EN KLQ E E A+L +I L+ ++ L+ + +LE+
Sbjct: 821 EMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEAL 880
Query: 230 TLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKD 289
AR E++ S AR+A L E+E Q + E+ + ++ +E + +K+
Sbjct: 881 VHARKEEKEAVS----ARRA------LENELEAAQGNLSQTTQEQKQLSEKLKEESEQKE 930
Query: 290 TLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQ 343
L+R E E+ +R + + + +A +E R +T EL+ ++ +E+
Sbjct: 931 QLRRLKNEMEN---ERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEK 981
Score = 32.7 bits (73), Expect = 0.91
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 2/130 (1%)
Query: 109 QLHGGLELEEETAFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATADLLS-SLE 167
+L LE EE L++R+L E + E D + +L + +E
Sbjct: 1157 ELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVE 1216
Query: 168 DLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELED 227
+ E RL KLQR +E + + L ++ +++K L + + MD++ +D
Sbjct: 1217 EAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLDDMDDD-DD 1275
Query: 228 LKTLARSLEE 237
L T SL E
Sbjct: 1276 LSTDGGSLYE 1285
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 55.1 bits (131), Expect = 2e-07
Identities = 72/297 (24%), Positives = 129/297 (43%), Gaps = 26/297 (8%)
Query: 196 RLGEEILALRKQLHSTQQALQFAKAMDEELEDL-KTLARSLEEQNRSLLAQARQAEKEQQ 254
+L +E LRK+L S + LQ ++ L L + L EQ L Q + ++++
Sbjct: 161 QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEE 220
Query: 255 HLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQ---LFECEHLICQRDTILSE 311
L + E L E+ +L + + ++++ + L +++ L Q L E E +C+++ + +
Sbjct: 221 RLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQ 280
Query: 312 RTRDVESLAQTLE-EYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLP 370
R +E + + LE E R QE LE RL +++ +EL E +LR+ L
Sbjct: 281 E-RLLEEVEKLLEQERRQEEQERLLERERLLDEV-------EELLEQERLRQQD-ERLWQ 331
Query: 371 PSLGLEIEAIRQKQEVATADLSNPLCGVWQ--WEEVIHETSEET----EFPSEAPAGGQR 424
E+E +R+ + + + L + + WE + + +E E +E + Q
Sbjct: 332 QETLRELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQL 391
Query: 425 NFQGEPAHPEEGRKEPSMWLTRREEEEDAESQVTADLPVPLGAPRPGDIPENPPERP 481
Q + G +EP R E A ++ PVP GA G P E P
Sbjct: 392 EQQVKELEKSGGAEEP------RGSESAAAARPVPGAPVPQGAWMCGQAGWTPQEHP 442
Score = 36.2 bits (82), Expect = 0.082
Identities = 45/187 (24%), Positives = 87/187 (46%), Gaps = 12/187 (6%)
Query: 175 RLVGENAKLQRSMETAEEGSARL--GEEILALRKQLHSTQQALQFAKAMDEELEDLKTLA 232
RL + +L+ E E RL EE L +++ Q+ L + + EE+E L
Sbjct: 235 RLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQE 294
Query: 233 RSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLK 292
R EEQ R LL + R ++ ++ L E E L++++ +L +++ +++ + +E+
Sbjct: 295 RRQEEQER-LLERERLLDEVEELL--EQERLRQQDERLW-QQETLRELERLRELERLREL 350
Query: 293 RQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPD 352
+L E E ++ L E+ + S + L +T +L ++ LE+ G
Sbjct: 351 ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK------SGGA 404
Query: 353 ELPEGAQ 359
E P G++
Sbjct: 405 EEPRGSE 411
Score = 34.7 bits (78), Expect = 0.24
Identities = 47/208 (22%), Positives = 92/208 (44%), Gaps = 23/208 (11%)
Query: 164 SSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILAL-RKQLHSTQQALQFAKAMD 222
++L+DLE + +L +++++ ++L E I +L R + + + +
Sbjct: 82 TTLQDLE-------SQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLG 134
Query: 223 EELEDLKT-LARSLEEQNRSLLAQARQAEKEQQHLVAEMETL------QEENGKLLA--- 272
L LK A L + + ++ Q + E HL E+E++ + EN ++L+
Sbjct: 135 RSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN 194
Query: 273 ERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQE 332
R + R QE + + + +L E E +C+++ L E+ E L + E R +
Sbjct: 195 RRQEERLREQEERLHEQ--EERLHEQEERLCEQEERLCEQE---ERLREQEERLREQEER 249
Query: 333 LRLEISRLEEQLSQTYEGPDELPEGAQL 360
L + RL EQ + E + L E +L
Sbjct: 250 LHEQEERLCEQEERLCEQEERLCEQEKL 277
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 55.1 bits (131), Expect = 2e-07
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 30/267 (11%)
Query: 155 ELQATADLLSSLE-DLELSNRRLVGENAKLQRSMETAEEGSARLGEEILA-------LRK 206
E+ DL+ +L LE+ + +LQ + ++ +GEE A L+
Sbjct: 1428 EIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQA 1487
Query: 207 QLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEE 266
L S ++AL+ K++ EEL + L + + +Q KE+ ++ + LQEE
Sbjct: 1488 ALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1547
Query: 267 NGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEY 326
KL+ E D +Q L+ ++LK L E L ++ ++ E +ESL +
Sbjct: 1548 RDKLITEMDRSLLENQSLSSSCESLKLAL---EGLTEDKEKLVKE----IESLKSSKIAE 1600
Query: 327 RVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEV 386
QE E+ + E L Q+YE E +++ V +EA+RQ+++
Sbjct: 1601 STEWQEKHKELQKEYEILLQSYENVSN--EAERIQHV-------------VEAVRQEKQE 1645
Query: 387 ATADLSNPLCGVWQWEEVIHETSEETE 413
L + + E+ + E +E E
Sbjct: 1646 LYGKLRSTEANKKETEKQLQEAEQEME 1672
Score = 55.1 bits (131), Expect = 2e-07
Identities = 47/196 (23%), Positives = 98/196 (50%), Gaps = 15/196 (7%)
Query: 167 EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHST----QQALQFAKAM- 221
++ ++ N + E +L+ ++ + E ++RL EEI +++ S ++A+Q A A
Sbjct: 2345 QEADIQNSKFSYE--QLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAEL 2402
Query: 222 ----DEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGV 277
D+E+++L+ L EE+N L + ++A + L+ ++T+++EN + A+ D
Sbjct: 2403 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSF 2462
Query: 278 KKRSQELAMEKDTL--KRQLFECEHL--ICQRDTILSERTRDVESLAQTLEEYRVTTQEL 333
K L ++D + Q E HL I ++D ++ E + L + + R +L
Sbjct: 2463 VKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2522
Query: 334 RLEISRLEEQLSQTYE 349
E ++L+ +L Q E
Sbjct: 2523 NSENAKLDAELIQYRE 2538
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/352 (23%), Positives = 154/352 (43%), Gaps = 51/352 (14%)
Query: 12 TAEMYLRERPEEARLGMPV-SLEEQI--LNSTFEACDPQRTGTVAVAQVLAYLEAVTGQG 68
T +Y + E A+L + SL++Q+ L+++ E C Q+ LE + Q
Sbjct: 2296 TRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGN----------LEGIIRQ- 2344
Query: 69 PQDARLQTLANSLDPNGEGPKATVDLDTFLVVMRDWIAACQLHGGLELEEETAFQGALTS 128
Q+A +Q S + L+T L R+ + +LH + ++E+
Sbjct: 2345 -QEADIQNSKFSYE----------QLETDLQASRELTS--RLHEEINMKEQKIIS----- 2386
Query: 129 RQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLED----LELSNRRLVGENAKLQ 184
L SG EA + A E D E++ +LLS E+ LE N++ V + +L
Sbjct: 2387 --LLSGKEEAIQVAIAELRQQHDK--EIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2442
Query: 185 RSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQN--RSL 242
+++T ++ + + ++ + K + S Q ++LE+ + L+ LE+ +
Sbjct: 2443 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEE-RHLSIILEKDQLIQEA 2501
Query: 243 LAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLF------ 296
A+ + ++E + L + M+ L EN KL AE ++ ++ KD+ ++QL
Sbjct: 2502 AAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQ 2561
Query: 297 --ECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQ 346
E E+ + + L E E L ++ + Q+L EI L+ +SQ
Sbjct: 2562 NKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQ 2613
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/237 (22%), Positives = 100/237 (42%), Gaps = 34/237 (14%)
Query: 150 EDPRPELQATADLLSSLED--------LELSNRRLVGENAK---LQRSMETAEEGSARLG 198
ED +L AD+ + ++ LE LVG LQ+ + AE+ + L
Sbjct: 234 EDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILS 293
Query: 199 EEILALRKQLHSTQQALQ--------FAKAMDEELEDLKTLARSLEEQNRSLLAQARQAE 250
+++ + + ++ + ++ + M+ E+ + K +L+E+ LL Q QA
Sbjct: 294 QQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAG 353
Query: 251 KEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILS 310
+ Q L + L++++ + E K S L+++K + Q C+ L Q +L
Sbjct: 354 QAQAELESRYSALEQKHKAEMEE-----KTSHILSLQKTGQELQS-ACDALKDQNSKLLQ 407
Query: 311 ERTRDVESLAQTLEEYRVTTQELRLEISRL--------EEQLSQTYEGPDELPEGAQ 359
++ AQT+++ Q+ EIS+ E SQT PD EG Q
Sbjct: 408 DKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQT-SFPDVYNEGTQ 463
Score = 43.1 bits (100), Expect = 7e-04
Identities = 61/266 (22%), Positives = 103/266 (38%), Gaps = 19/266 (7%)
Query: 98 LVVMRDWIAACQLHGGLELEEETAFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQ 157
L + +I + GG L E + L+ S EE +E + +LQ
Sbjct: 104 LTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSS----TEEEMEIEKI-----KHKLQ 154
Query: 158 ATADLLSSLE-DLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQ 216
+L+S+L+ L + +++ ++ E I L+ QL TQ
Sbjct: 155 EKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQA 214
Query: 217 FAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDG 276
+ + E+ +T R E++ L+ QA + QQ L L+E L+
Sbjct: 215 AQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQV 274
Query: 277 VKKRSQELA---MEKDTLKRQL--FECEHLICQRDTILSERTRD---VESLAQTLEEYRV 328
V QEL L +QL E EH R+T+ +ER +E + + E ++
Sbjct: 275 VDLLQQELTAAEQRNQILSQQLQQMEAEHNTL-RNTVETEREESKILLEKMELEVAERKL 333
Query: 329 TTQELRLEISRLEEQLSQTYEGPDEL 354
+ L+ E+ L EQ Q + EL
Sbjct: 334 SFHNLQEEMHHLLEQFEQAGQAQAEL 359
Score = 41.6 bits (96), Expect = 0.002
Identities = 60/270 (22%), Positives = 113/270 (41%), Gaps = 33/270 (12%)
Query: 105 IAACQLHGGLELEEETAFQGALTSRQLPSGCPEAEEPANLESFGGE--DPRPELQATADL 162
+A + L+ E +TA LT + + +E E D + + + L
Sbjct: 773 LAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTL 832
Query: 163 LSSLEDLELSNRRLVGENAKLQRSMET-AEEGSARLGEEILALRKQLHSTQQALQFAKAM 221
+ SL+ + V E A+ R + + EE S L ++ L + K + +
Sbjct: 833 IRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKM----------DQLL 882
Query: 222 DEELEDLKTLARSLEEQNR-------SLLAQARQAEKEQQHLVAEMETLQEENGKLLAER 274
E+ D++TL +++EE+++ S+ + Q +E+ L E++TL+E+ L
Sbjct: 883 LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 942
Query: 275 DGVKKRSQELAMEKDTLKRQLFEC--------EHLICQRDTILSERTRDVESLAQTLEEY 326
+ K++ +E LK+ E E L + D + E E + L+
Sbjct: 943 EAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKEN----EQRKRKLQAA 998
Query: 327 RVTTQELRLEISRLEEQLSQTY-EGPDELP 355
+ +EL +SRLEE+L+ E E+P
Sbjct: 999 LINRKELLQRVSRLEEELANLKDESKKEIP 1028
Score = 41.2 bits (95), Expect = 0.003
Identities = 68/313 (21%), Positives = 132/313 (42%), Gaps = 29/313 (9%)
Query: 162 LLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH---STQQALQFA 218
LLSS ++ R+ E L + ++ L EE+ L+ Q+ S Q L+
Sbjct: 1717 LLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEAT 1776
Query: 219 KAMDEEL----EDLKTLARSLEEQN------RSLLAQARQAEKEQQHLVAEMETLQEENG 268
+ D + E +++ EEQ+ R +++ + K V++ + +E
Sbjct: 1777 EKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEIN 1836
Query: 269 KLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSE---RTRDVESLAQTLEE 325
L + D +K+R L EK K E+ +++T+LS+ + +++ L + + +
Sbjct: 1837 NYLQQIDQLKERIAGLEEEKQKNKEFSQTLEN---EKNTLLSQISTKDGELKMLQEEVTK 1893
Query: 326 YRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLG---LEIEAIRQ 382
+ Q+++ E+SR+ + E D+L E R + L S+G ++ +
Sbjct: 1894 MNLLNQQIQEELSRVTKLKETAEEEKDDLEE----RLMNQLAELNGSIGNYCQDVTDAQI 1949
Query: 383 KQEVATADLSNPLCGVWQWEEVIHE-TSEETEFPSEAPAGGQRNFQGEPAHPEEGRKEPS 441
K E+ +++ N V + EE + E+T+ SE QG A E G K +
Sbjct: 1950 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG--AQKEPGNKSHA 2007
Query: 442 MWLTRREEEEDAE 454
L +E+ E
Sbjct: 2008 KELQELLKEKQQE 2020
Score = 40.8 bits (94), Expect = 0.003
Identities = 46/193 (23%), Positives = 86/193 (44%), Gaps = 29/193 (15%)
Query: 155 ELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQA 214
EL +L + ++ LE+ N +L +TA + L +Q+HS
Sbjct: 755 ELSMVTELRAQVKQLEM-NLAEAERQRRLDYESQTAHDN---------LLTEQIHSLSIE 804
Query: 215 LQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMET-LQEENGKLLAE 273
AK+ D ++E L+ ++ Q EQ L+ +++ LQ + ++L
Sbjct: 805 ---AKSKDVKIEVLQNELDDVQLQF-----------SEQSTLIRSLQSQLQNKESEVLEG 850
Query: 274 RDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQEL 333
+ V+ S ++ + L + L + E I + D +L E+ RDVE+L QT+EE E+
Sbjct: 851 AERVRHISSKV----EELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEI 906
Query: 334 RLEISRLEEQLSQ 346
++ QL++
Sbjct: 907 SFSMTEKMVQLNE 919
Score = 40.0 bits (92), Expect = 0.006
Identities = 63/312 (20%), Positives = 132/312 (42%), Gaps = 32/312 (10%)
Query: 157 QATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQ 216
++ AD+ S + ++G A LQ E ++ + +L + L S+ ++L+
Sbjct: 1518 KSLADVESQVSAQNKEKDTVLGRLALLQ---EERDKLITEMDRSLLE-NQSLSSSCESLK 1573
Query: 217 FAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQE--ENGKLLAER 274
A ++ ED + L + +E S +A++ + +++ + L E E L + EN AER
Sbjct: 1574 LA--LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1631
Query: 275 -----DGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVT 329
+ V++ QEL + + + E E L E +++E + + + ++ +
Sbjct: 1632 IQHVVEAVRQEKQELYGKLRSTEANKKETEKQ-------LQEAEQEMEEMKEKMRKFAKS 1684
Query: 330 TQELRLEISRLEEQL-SQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVAT 388
Q+ LE+ ++L ++ + D E + LL + ++ E R K E T
Sbjct: 1685 KQQKILELEEENDRLRAEVHPAGDTAKECME-------TLLSSNASMKEELERVKMEYET 1737
Query: 389 ADLSNPLCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQGEPAHPEEGR--KEPSMWLTR 446
LS + ++ + E ++ + E Q N + H + +E + +
Sbjct: 1738 --LSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPG 1795
Query: 447 REEEEDAESQVT 458
EE+D+ S T
Sbjct: 1796 ETEEQDSLSMST 1807
Score = 38.9 bits (89), Expect = 0.013
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 42/213 (19%)
Query: 165 SLEDLELSNRRLV----------GENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQA 214
S +DLE++ L E A + ++ + +AR+ + L L+K+L S +++
Sbjct: 2052 SQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKES 2111
Query: 215 LQFA-KAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAE 273
++ K DE+LE R LE+ L + + +++ L E L+E G++
Sbjct: 2112 VKSQMKQKDEDLE------RRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVT 2165
Query: 274 RDGVKKRSQELAMEKDTLKRQLF----ECEHLICQRDTILSERTR--------------- 314
+ K Q+L D+ QL L RD ++ E +
Sbjct: 2166 LNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2225
Query: 315 ------DVESLAQTLEEYRVTTQELRLEISRLE 341
+ L L + + +EL++ ISRLE
Sbjct: 2226 IRLKEDNCSVLKDQLRQMSIHMEELKINISRLE 2258
Score = 36.6 bits (83), Expect = 0.063
Identities = 40/199 (20%), Positives = 82/199 (41%), Gaps = 28/199 (14%)
Query: 161 DLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKA 220
+L E L S + E ++Q +E + L ++ + T++ LQ A+
Sbjct: 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQ 1669
Query: 221 -MDEELEDLKTLARS-------LEEQNRSLLAQARQA------------------EKEQQ 254
M+E E ++ A+S LEE+N L A+ A ++E +
Sbjct: 1670 EMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELE 1729
Query: 255 HLVAEMETLQEENGKLLAERDGVKKRSQEL--AMEKDTLKRQLFECEHLICQRDTILSER 312
+ E ETL ++ L++E+D + + Q+L +E + K+ E + + E
Sbjct: 1730 RVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEG 1789
Query: 313 TRDVESLAQTLEEYRVTTQ 331
T+ + + + ++T+
Sbjct: 1790 TQSIPGETEEQDSLSMSTR 1808
Score = 34.7 bits (78), Expect = 0.24
Identities = 43/194 (22%), Positives = 80/194 (41%), Gaps = 10/194 (5%)
Query: 162 LLSSLEDLELSNRRLVGE----NAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQF 217
L S ++DL N +L E L + + + +L E L K+L + L+
Sbjct: 2515 LRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEE 2574
Query: 218 A-KAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDG 276
K +E EDL+ +L+E+ + L + + L ++ LQEE G L
Sbjct: 2575 KLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-GTLGLYHAQ 2633
Query: 277 VKKRSQEL----AMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQE 332
+K + +E+ A+ + KR E L+C + + + L + L+
Sbjct: 2634 LKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGI 2693
Query: 333 LRLEISRLEEQLSQ 346
+R E EE++++
Sbjct: 2694 MRNETETAEERVAE 2707
Score = 32.3 bits (72), Expect = 1.2
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 23/195 (11%)
Query: 182 KLQRSMETAEEGSARL----------GEEILALRKQLHSTQQALQFAKAMDEELEDLKTL 231
KLQ + AEE + GE I ++ ++ F +EE +
Sbjct: 577 KLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEE-----SS 631
Query: 232 ARSLEEQNRSLLAQARQAEK-EQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDT 290
++E++ S Q+R +E+ E+++ +++ K L+ + + Q+ E +
Sbjct: 632 LPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQD---ELER 688
Query: 291 LKRQLFECEHLICQRDTI----LSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQ 346
LK Q+ E E + I L E+ +++ +L Q +EE++ + L E+ Q
Sbjct: 689 LKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQ 748
Query: 347 TYEGPDELPEGAQLR 361
EL +LR
Sbjct: 749 LLSQVKELSMVTELR 763
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/280 (24%), Positives = 123/280 (43%), Gaps = 37/280 (13%)
Query: 157 QATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQ 216
QA+ S +DL L G + QR+ E RL E+ ALR+QL Q++++
Sbjct: 1621 QASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELR----RLSSEVEALRRQLLQEQESVK 1676
Query: 217 FAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQ---QHLVAEMETLQEENGKLLAE 273
A +E + +++E+++RSL + E+ Q ++L E L+EE L E
Sbjct: 1677 QAHLRNEHFQ------KAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLE 1730
Query: 274 RDGVKKRSQELAMEKDT----LKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVT 329
D +++ E +K+ L+ QL + + ++++ R+ E+L Q +E+++
Sbjct: 1731 YDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQ 1790
Query: 330 TQELRLEISRLEEQLSQTYEGPDEL--------PEGAQLRRVGWTELLPPSLGLEIEA-I 380
E I + Q +Q + + L + A+L+R+ EL LE E +
Sbjct: 1791 ALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLE-DELNRAKSTLEAETRV 1849
Query: 381 RQKQEVATADLSNPLCGVWQW-------EEVIHETSEETE 413
+Q+ E + N L QW EE I + E E
Sbjct: 1850 KQRLECEKQQIQNDLN---QWKTQYSRKEEAIRKIESERE 1886
Score = 45.4 bits (106), Expect = 1e-04
Identities = 60/237 (25%), Positives = 100/237 (42%), Gaps = 16/237 (6%)
Query: 161 DLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEIL---ALRKQLHSTQQALQF 217
+L + L+ L NR L E +L S+ A E R E L A ++ +Q L+
Sbjct: 1234 NLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEI 1293
Query: 218 A--KAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERD 275
+ M + ED +SLEE +++ + KE + L AE QEE + +
Sbjct: 1294 ELKQVMQQRSEDNARHKQSLEEAAKTI----QDKNKEIERLKAEF---QEEAKRRWEYEN 1346
Query: 276 GVKKRSQELAMEKDTLKRQLFECEHLICQRDT--ILSERTRDVESLAQTLEEYRVTTQEL 333
+ K E +LK Q FE E I + + ++ D ++ + L
Sbjct: 1347 ELSKVRNNYDEEIISLKNQ-FETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSL 1405
Query: 334 RLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATAD 390
EI RL+ L+QT E + E Q ++ +E+ LE+E +RQ ++ T +
Sbjct: 1406 SEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVE-LRQVTQMRTEE 1461
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/203 (21%), Positives = 93/203 (45%), Gaps = 19/203 (9%)
Query: 159 TADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEI---LALRKQLHSTQQAL 215
T+ + +++L NR L E +L+ ++ E R+ E+I A ++ +Q L
Sbjct: 1388 TSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQL 1447
Query: 216 -----QFAKAMDEE----LEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEE 266
Q + EE + L A++++++N+ + + +KE + + L++E
Sbjct: 1448 EVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETN----DRKCLEDE 1503
Query: 267 NGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERT---RDVESLAQTL 323
N +L + ++K + + LK Q E L + + ERT +D+ +L
Sbjct: 1504 NARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSL 1563
Query: 324 EEYRVTTQELRLEISRLEEQLSQ 346
+E ++ Q++ E++RL+ S+
Sbjct: 1564 KELQLQKQKVEEELNRLKRTASE 1586
Score = 41.6 bits (96), Expect = 0.002
Identities = 67/312 (21%), Positives = 132/312 (42%), Gaps = 59/312 (18%)
Query: 160 ADLLSSLEDLELSNRRL--VGENAKLQRSMET--------AEEGSARLGEEILALRKQLH 209
+++L SLEDL+L N ++ + E +L R + ++ + E + +L
Sbjct: 1018 SEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLA 1077
Query: 210 STQQALQFA------------------KAMDE-------ELEDLKTLARSLEEQ------ 238
S ++ + A K ++E E+ED K +S+E++
Sbjct: 1078 SLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKN 1137
Query: 239 NRSLLAQARQAEKEQ---QHLVAEMETLQE----ENGKLLAERDGVKKRSQELAM----- 286
+ L +ARQ EKE Q L +E ++ E ++L + +G +KR E +
Sbjct: 1138 DYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRN 1197
Query: 287 ---EKDTLKRQLFECEHLICQR--DTILSERTRDVESLAQTLEEYRVTTQELRLEISRLE 341
E+ + R +E E I + I ++ D ++L L+ ++L+ EI RL
Sbjct: 1198 HYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLN 1257
Query: 342 EQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQW 401
+ + Q E E A ++ +E++ LEIE ++Q + + D + + +
Sbjct: 1258 DSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIE-LKQVMQQRSEDNARHKQSLEEA 1316
Query: 402 EEVIHETSEETE 413
+ I + ++E E
Sbjct: 1317 AKTIQDKNKEIE 1328
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 13/173 (7%)
Query: 191 EEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSL----EEQNRSLLAQA 246
EEG+ + E + + H ++ + E+ KT + + E+ +++L Q
Sbjct: 1180 EEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQL 1239
Query: 247 RQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFEC-EHLICQR 305
+ +E + L E+ L + + + ++R++E A+++ ++ + +HL +
Sbjct: 1240 DRLSRENRDLKDEIVRLNDS----ILQATEQRRRAEENALQQKACGSEIMQKKQHLEIEL 1295
Query: 306 DTILSERTRDVESLAQTLEEYRVTTQELRLEISRL----EEQLSQTYEGPDEL 354
++ +R+ D Q+LEE T Q+ EI RL +E+ + +E +EL
Sbjct: 1296 KQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENEL 1348
Score = 40.0 bits (92), Expect = 0.006
Identities = 47/210 (22%), Positives = 87/210 (41%), Gaps = 20/210 (9%)
Query: 166 LEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQAL-QFAKAMDEE 224
+++ EL+ R+ E +R+++ ++ R + L+ Q ++ L + + E+
Sbjct: 1530 VQEQELTRLRIDYERVSQERTVK--DQDITRFQNSLKELQLQKQKVEEELNRLKRTASED 1587
Query: 225 LEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGV------K 278
K L LE RSL QA + Q L + L +RD + K
Sbjct: 1588 SCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREK 1647
Query: 279 KRSQE----LAMEKDTLKRQLFECEHLICQR-------DTILSERTRDVESLAQTLEEYR 327
+R+QE L+ E + L+RQL + + + Q + +++R + +E +
Sbjct: 1648 QRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 1707
Query: 328 VTTQELRLEISRLEEQLSQTYEGPDELPEG 357
T+ L E LEE+L D+L G
Sbjct: 1708 SLTENLTKEHLMLEEELRNLRLEYDDLRRG 1737
Score = 38.9 bits (89), Expect = 0.013
Identities = 53/210 (25%), Positives = 92/210 (43%), Gaps = 20/210 (9%)
Query: 157 QATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQ 216
Q+ D +++D RL K + E+ +ARL L+K S + +
Sbjct: 1467 QSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETIN 1526
Query: 217 FAKAMDEELEDLK------TLARSLEEQN-----RSLLAQARQAEKEQQHLVAEMETLQE 265
K ++EL L+ + R++++Q+ SL Q +K ++ L T E
Sbjct: 1527 KLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASE 1586
Query: 266 EN---GKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQT 322
++ KL E +G+++ +E A++ L +QL E ++ +R + RDV L
Sbjct: 1587 DSCKRKKLEEELEGMRRSLKEQAIKITNLTQQL-EQASIVKKRSEDDLRQQRDV--LDGH 1643
Query: 323 LEEYRVTTQELR---LEISRLEEQLSQTYE 349
L E + T +ELR E+ L QL Q E
Sbjct: 1644 LREKQRTQEELRRLSSEVEALRRQLLQEQE 1673
Score = 38.1 bits (87), Expect = 0.022
Identities = 45/189 (23%), Positives = 81/189 (42%), Gaps = 25/189 (13%)
Query: 167 EDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELE 226
E L + + L + A+LQR + + L E ++++L +Q +Q +L
Sbjct: 1813 ESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAET-RVKQRLECEKQQIQ------NDLN 1865
Query: 227 DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAER------DGVKKR 280
KT EE R + ++ ++E+E+ L +E+E LQ E K + ER D ++
Sbjct: 1866 QWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEI-KRIEERCRRKLEDSTRET 1924
Query: 281 SQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRL 340
+L E+ +R++ + L +R QT E+ V T +L + R
Sbjct: 1925 QSQLETERSRYQREIDK-----------LRQRPYGSHRETQTECEWTVDTSKLVFDGLRK 1973
Query: 341 EEQLSQTYE 349
+ Q YE
Sbjct: 1974 KVTAMQLYE 1982
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 54.7 bits (130), Expect = 2e-07
Identities = 83/363 (22%), Positives = 143/363 (39%), Gaps = 69/363 (19%)
Query: 167 EDLELSNRRLVGENAKLQRSMETAEEGSARLGE------EILALRKQLHSTQQALQ---- 216
+ L+L +RL + Q+ ET EE + E I AL++++ +Q L+
Sbjct: 99 QQLQLKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKNQAE 158
Query: 217 -FAKAMDEELE-DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQ---------- 264
A +++L+ D R L+E S ++ +AE + Q L +E +
Sbjct: 159 TIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKY 218
Query: 265 --------EENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDV 316
+E ++ + + +R++ E +TL+ QL H + I ++ DV
Sbjct: 219 DEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQI--QKAPDV 276
Query: 317 ESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLE 376
E + L T L +E++ E +++Q L E Q + T+L S +
Sbjct: 277 EQAIEVL-----TRSSLEVELAAKEREIAQ-------LVEDVQRLQASLTKLRENSAS-Q 323
Query: 377 IEAIRQKQEVATA---DLSNPLCGVWQWEEVIHETS--EETEFPSEAPAGGQ-------- 423
I + Q+ + L L G +EEV E + + EF AG Q
Sbjct: 324 ISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEV 383
Query: 424 ------RNFQGEPAHPEEGRKEPSMWLTRREEEEDAESQVTADLPVPLGAPRPGDIPENP 477
R+ Q E A + S RR+ ++ ES+ LP AP P +P NP
Sbjct: 384 LLLEKNRSLQSENAALRISNSDLS-GSARRKGKDQPESRRPGSLP----APPPSQLPRNP 438
Query: 478 PER 480
E+
Sbjct: 439 GEQ 441
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 54.3 bits (129), Expect = 3e-07
Identities = 60/226 (26%), Positives = 103/226 (45%), Gaps = 26/226 (11%)
Query: 159 TADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFA 218
TADL L E S RLV E L+R ++ A + A L EE L + +T +
Sbjct: 1344 TADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAR 1403
Query: 219 KA-MDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGV 277
+A + +E+EDL +EQ+ + +QAEK++ L+++M+ L+ E + L++ G
Sbjct: 1404 EAALRKEVEDLT------KEQSET----RKQAEKDRSALLSQMKILESELEEQLSQHRGC 1453
Query: 278 KKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEI 337
K+++ + E + D L + + ++ A E R +E + EI
Sbjct: 1454 AKQAEAVT-----------ALEQQVASLDKHLRNQRQFMDEQAAEREHER---EEFQQEI 1499
Query: 338 SRLEEQLSQTYEGPDELPEGAQLRRV-GWTELLPPSLGLEIEAIRQ 382
RLE QL Q + P +Q + G ELL L +++ +
Sbjct: 1500 QRLEGQLRQAAKPQPWGPRDSQQAPLDGEVELLQQKLREKLDEFNE 1545
Score = 40.4 bits (93), Expect = 0.004
Identities = 47/201 (23%), Positives = 80/201 (39%), Gaps = 14/201 (6%)
Query: 151 DPRPELQATADLLSSLE-DLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH 209
D +L+ + S E + N K Q +E +E SA E L +LH
Sbjct: 1276 DSSRQLEEARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAE----LALELH 1331
Query: 210 STQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGK 269
TQ L+ K E DLK + E+ L+ + ++ Q E L+EE +
Sbjct: 1332 KTQGTLEGFKV---ETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTR 1388
Query: 270 LLA--ERDGVKKRSQELAMEK---DTLKRQLFECEHLICQRDTILSERTRDVESLAQTLE 324
L + E ++E A+ K D K Q + R +LS+ L + L
Sbjct: 1389 LWSRGEATATDAEAREAALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELEEQLS 1448
Query: 325 EYRVTTQELRLEISRLEEQLS 345
++R ++ ++ LE+Q++
Sbjct: 1449 QHRGCAKQAE-AVTALEQQVA 1468
Score = 39.7 bits (91), Expect = 0.007
Identities = 54/223 (24%), Positives = 99/223 (44%), Gaps = 34/223 (15%)
Query: 137 EAEEPA---NLESFGGEDPRPELQATAD---LLSSLEDLELSNRRLVGENAKLQRSMETA 190
EA E A +E E QA D LLS ++ LE ++L+ + +
Sbjct: 1401 EAREAALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILE----------SELEEQL-SQ 1449
Query: 191 EEGSARLGEEILALRKQLHSTQQALQFAKA-MDEELEDLKTLARSLEEQNRSLLAQARQA 249
G A+ E + AL +Q+ S + L+ + MDE+ + + +++ + L Q RQA
Sbjct: 1450 HRGCAKQAEAVTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEGQLRQA 1509
Query: 250 EK---------EQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEH 300
K +Q L E+E LQ++ + L E + ELA++K++ RQ+ E
Sbjct: 1510 AKPQPWGPRDSQQAPLDGEVELLQQKLREKLDEFN-------ELAIQKESADRQVLMQEE 1562
Query: 301 LICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQ 343
I + + + + V L + +E+ + + L + L++Q
Sbjct: 1563 EIKRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQ 1605
Score = 37.7 bits (86), Expect = 0.028
Identities = 67/301 (22%), Positives = 116/301 (38%), Gaps = 67/301 (22%)
Query: 210 STQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGK 269
S Q++ Q ++++ E +++ L L + L A ++ E EQ A L+EE +
Sbjct: 2616 SRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQLR 2675
Query: 270 LLAERDGVKKRSQELAME---------------------KDTLKRQL----FECEHLICQ 304
L K +EL KD L+++L CE L+ Q
Sbjct: 2676 HLQRESQSAKALEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQ 2735
Query: 305 RDTILSERTRDVES-------LAQTLEEYRVTTQELRLE----------------ISRLE 341
+ LSE +D+ + L++ L R+ T++L + +L+
Sbjct: 2736 ERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLK 2795
Query: 342 EQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQW 401
E+ S+ + + E Q + + + L EA+R+++EV +A L + +
Sbjct: 2796 EEKSRVVD-LQAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEV-SATLKSTV------ 2847
Query: 402 EEVIHETSEE----TEFPSEAPAGGQRNFQGEPAHP----EEGRKEPSMWLTRREEEEDA 453
E +H E E E PA Q E +HP +EGRK R+ A
Sbjct: 2848 -EALHTQKRELRCSLEREREKPAWLQAEL--EQSHPRLKEQEGRKAARRSAEARQSPAAA 2904
Query: 454 E 454
E
Sbjct: 2905 E 2905
Score = 37.4 bits (85), Expect = 0.037
Identities = 69/288 (23%), Positives = 109/288 (37%), Gaps = 53/288 (18%)
Query: 132 PSGCPEAEEPANLESFGGEDPRPELQATADLLSSLE----DLELSNRRLVGENAKLQ-RS 186
PSG P LE R E + DL LE DLE N ++ N KL ++
Sbjct: 1629 PSGSPPEGPEIQLEVTQRALLRRESEVL-DLKEQLEKMKGDLESKNEEILHLNLKLDMQN 1687
Query: 187 METAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQA 246
+TA ++LR +L +L+ E+E+LK +L+E N+ L +
Sbjct: 1688 SQTA-----------VSLR-ELEEENTSLKVIYTRSSEIEELKATIENLQE-NQKRLQKE 1734
Query: 247 RQAEKEQQHLVAEM-------------ETLQEENGKLLAE---------RDGVKKRSQEL 284
+ E EQ H V E E + G L +E R + E
Sbjct: 1735 KAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGELEA 1794
Query: 285 AME-KDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQ 343
A+E K+ L R L + E Q L +R + E A+ + EL ++ E +
Sbjct: 1795 ALEAKEALSRLLADQERRHSQALEALQQRLQGAEEAAE------LQLAELERNVALREAE 1848
Query: 344 LSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATADL 391
+ E + + E LEI+A+ Q++ +A+L
Sbjct: 1849 VEDMASRIQEFEAALKAKEATIAE-----RNLEIDALNQRKAAHSAEL 1891
Score = 33.5 bits (75), Expect = 0.53
Identities = 38/158 (24%), Positives = 71/158 (44%), Gaps = 6/158 (3%)
Query: 199 EEILALRKQLHSTQQALQFAKA-MDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLV 257
E+ +++K L + Q ++ K+ + E + + L+RSL E + +L ++ L
Sbjct: 2590 EKANSVQKLLAAEQTVVRDLKSDLCESRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELK 2649
Query: 258 AEMETLQEENGKLLAERDGVKKRS-QELAMEKDTLKRQLFECEHLICQRDTILSERTRDV 316
A ++ L+ E GK A + +++ + L E + K E L +T ++ +R
Sbjct: 2650 AALQELESEQGKGRALQSQLEEEQLRHLQRESQSAK----ALEELRASLETQRAQSSRLC 2705
Query: 317 ESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDEL 354
+L +ELR+E SR E L+Q EL
Sbjct: 2706 VALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSEL 2743
Score = 32.3 bits (72), Expect = 1.2
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 13/128 (10%)
Query: 166 LEDLELSNRRLVGENA-KLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEE 224
LEDLE + E +L+ + E+ A+ EEI L QL S + + Q + E+
Sbjct: 431 LEDLEFKFKESEKEKQLELENLQASYEDLKAQSQEEIRRLWSQLDSARTSRQELSELHEQ 490
Query: 225 LEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQEL 284
L LAR+ ++ L Q +Q EK Q +E+E L+ K L RD K ++L
Sbjct: 491 L-----LARTSRVED---LEQLKQREKTQHE--SELEQLRIYFEKKL--RDAEKTYQEDL 538
Query: 285 AMEKDTLK 292
+ + L+
Sbjct: 539 TLLQQRLQ 546
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 54.3 bits (129), Expect = 3e-07
Identities = 75/329 (22%), Positives = 146/329 (44%), Gaps = 25/329 (7%)
Query: 155 ELQATADLLSSLED---LELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHST 211
+ Q +L ++L+D LE N L G+ ++L+ + ++ + E+L QL +
Sbjct: 359 QAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETL 418
Query: 212 QQALQFAKAMDEELED-LKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKL 270
+Q A + +L+ ++ L +Q LLA+ E+E+Q L + + LQ L
Sbjct: 419 KQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNL 478
Query: 271 LAERDGVKKRSQ----ELAMEKDTLKRQLFECEHLICQRDTILSERTRDVES----LAQT 322
++ +++ SQ L + +L +L I Q+D L+ + + LAQT
Sbjct: 479 SQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQT 538
Query: 323 LEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQ 382
L++ +Q LR ++ +L L Q + E+ E + R + L + E EA +
Sbjct: 539 LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQL-ATAAEEREASLR 597
Query: 383 KQEVATADLSNPLCGVWQWEEV--IHETSEETEFPSEAPAGGQRNF-QGEPAHPEEGRKE 439
+++ A L + E+ + ++ + +EA Q + Q + E RK
Sbjct: 598 ERDAALKQLE-----ALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKV 652
Query: 440 PSMWL---TRREEEEDAESQVTADLPVPL 465
+ T R+E+ +A++QV A+L + L
Sbjct: 653 EELQACVETARQEQHEAQAQV-AELELQL 680
Score = 46.6 bits (109), Expect = 6e-05
Identities = 53/204 (25%), Positives = 88/204 (43%), Gaps = 28/204 (13%)
Query: 184 QRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRS-- 241
Q +++ E + ++G E+ LR L +Q Q + E + +AR +E+ R+
Sbjct: 964 QAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQE-----REVARLTQERGRAQA 1018
Query: 242 --LLAQARQAEKEQQHLVA------EMETLQEENGKLLAERDGVKKRSQELAMEKDTLKR 293
L +A +AE E + A E TLQE L E++G + QELA +
Sbjct: 1019 DLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEG---KDQELAKLRGLEAA 1075
Query: 294 QLFECEHL---ICQRDTILSERTRDVESLAQTLEEYRVTTQE-------LRLEISRLEEQ 343
Q+ E E L + Q L+++ ++ S + E T+ LR E+S+LE+Q
Sbjct: 1076 QIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQ 1135
Query: 344 LSQTYEGPDELPEGAQLRRVGWTE 367
+ E D L + R E
Sbjct: 1136 CQKQQEQADSLERSLEAERASRAE 1159
Score = 46.6 bits (109), Expect = 6e-05
Identities = 84/328 (25%), Positives = 139/328 (42%), Gaps = 53/328 (16%)
Query: 153 RPELQATADLLSSLED-LELSNRRLV---GENAKLQRSMETAEE---------------- 192
R E + L+SSLE+ + + NR+++ GE+ +L+R + E
Sbjct: 1217 RQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAET 1276
Query: 193 --GSARLGEEILALRKQLHSTQQALQFAKAMDEEL-EDLKTLARSLEEQNRSLLA-QARQ 248
SAR E ALR+++ S ++ + + E L ++L + A EE + L A Q +
Sbjct: 1277 ASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKF 1336
Query: 249 AEKEQ------------QHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLF 296
+KEQ Q LV+E+ + +L AE+ +KR +E +E+
Sbjct: 1337 FQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHRE-ELEQSKQAAGGL 1395
Query: 297 ECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPE 356
E L QR+ ++ L Q + E T Q+LR E + EQLS + L E
Sbjct: 1396 RAELLRAQRE------LGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAE 1449
Query: 357 GAQLRRVG-WTELLPPSLGLEIEAIRQK--QEVAT--ADLSNPLCGVWQWEEVIHETSEE 411
+ R +G L L +E++ R+K QE+A AD L V + T+ E
Sbjct: 1450 --ENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEV---QREAQSTARE 1504
Query: 412 TEFPSEAPAGGQRNFQGEPAHPEEGRKE 439
E + G + E +E R++
Sbjct: 1505 LEVMTAKYEGAKVKVLEERQRFQEERQK 1532
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/198 (20%), Positives = 88/198 (44%), Gaps = 11/198 (5%)
Query: 162 LLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAM 221
L + +E LE+ R + +L + + +++ S +++ A++ Q +QQ Q +A
Sbjct: 1533 LTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQ 1592
Query: 222 DEELEDLKTLARSLEEQNRSLLAQA-------RQAEKEQQHLVAEMETLQEENGKLLAER 274
EL+ + E + + +A +Q +E Q + +E LQ+EN +L AE
Sbjct: 1593 LNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEA 1652
Query: 275 DGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELR 334
+ + Q+ ++ ++ C HL Q + L + + + L +++V T L+
Sbjct: 1653 ERLGHELQQAGLKTKEAEQ---TCRHLTAQVRS-LEAQVAHADQQLRDLGKFQVATDALK 1708
Query: 335 LEISRLEEQLSQTYEGPD 352
+ + QL + + D
Sbjct: 1709 SREPQAKPQLDLSIDSLD 1726
Score = 45.1 bits (105), Expect = 2e-04
Identities = 84/348 (24%), Positives = 140/348 (40%), Gaps = 46/348 (13%)
Query: 117 EEETAFQGALTS-RQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLEDLELSNRR 175
++E A QG QL S + E+ L+ + L ++ E+ E S R
Sbjct: 541 QQEQASQGLRHQVEQLSSSLKQKEQ--QLKEVAEKQEATRQDHAQQLATAAEEREASLRE 598
Query: 176 LVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKT-LARS 234
+A L++ +E +A+L EIL ++QL +A A+ + + K L+R
Sbjct: 599 ---RDAALKQLEALEKEKAAKL--EIL--QQQLQVANEARDSAQTSVTQAQREKAELSRK 651
Query: 235 LEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQ 294
+EE ++ + ARQ + E Q VAE+E + E++ V A EKD L+ Q
Sbjct: 652 VEEL-QACVETARQEQHEAQAQVAELELQLRSEQQKATEKERV-------AQEKDQLQEQ 703
Query: 295 LFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDEL 354
L + + L E R A LEE + EL+ E L EQ + + +E
Sbjct: 704 LQALKESLKVTKGSLEEEKR---RAADALEEQQRCISELKAETRSLVEQHKRERKELEEE 760
Query: 355 PEG-----AQLRRVGWTELLPPSLGLEIEAIRQKQEVATADLSNPLCGVWQWEEVIHETS 409
G A+L+++G EA + + EV +L+ + E S
Sbjct: 761 RAGRKGLEARLQQLG-------------EAHQAETEVLRRELAEAMAAQHTAE------S 801
Query: 410 EETEFPSEAPAGGQRNFQGEPAHPEEGRKEPSMWLTRREEEEDAESQV 457
E + E A +R + + G +T +EE E A ++
Sbjct: 802 ECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQEL 849
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/187 (23%), Positives = 80/187 (42%), Gaps = 9/187 (4%)
Query: 168 DLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHST-QQALQFAKAMDEELE 226
DL R +LQ ++ E ++ +E L + QL ALQ K ++E+ E
Sbjct: 322 DLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNE 381
Query: 227 DLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAM 286
L+ LEE L Q + E V ++ETL++E L A ++ R + L
Sbjct: 382 ILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLET 441
Query: 287 EKDTLKRQLF----ECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQ----ELRLEIS 338
E+ + +L E Q +++++ + +L+Q EE +Q L +++
Sbjct: 442 ERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVA 501
Query: 339 RLEEQLS 345
L +L+
Sbjct: 502 SLTSELT 508
Score = 43.9 bits (102), Expect = 4e-04
Identities = 67/292 (22%), Positives = 114/292 (39%), Gaps = 36/292 (12%)
Query: 106 AACQLHGGLELEEETAFQGALTS------RQLPSGCPEAEEPANLESFGGEDPRPELQAT 159
AA + ELE+ G L + R+L P ++ A E + R E +
Sbjct: 1375 AAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTA-QQLRAEKASY 1433
Query: 160 ADLLSSLED---LELSNRRLVGENAKLQRSMETAEEGSAR--LGEEILALRKQLHSTQQA 214
A+ LS L+ L R +GE A L R E AR +E+ A+R +
Sbjct: 1434 AEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAE 1493
Query: 215 LQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQ---------- 264
+Q + +L+ + E +L + ++ ++E+Q L A++E L+
Sbjct: 1494 VQ--REAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQV 1551
Query: 265 EENGKLLAERDGVKKRSQ-----------ELAMEKDTLKRQLFECEHLICQRDTILSERT 313
EE K LA+ D K Q E E L+ QL E + + Q++
Sbjct: 1552 EELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYK 1611
Query: 314 RDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPE-GAQLRRVG 364
+E + + QEL+ ++ LE+ + E E G +L++ G
Sbjct: 1612 LQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAG 1663
Score = 43.5 bits (101), Expect = 5e-04
Identities = 59/263 (22%), Positives = 109/263 (41%), Gaps = 26/263 (9%)
Query: 115 ELEEETAFQGALTSRQLPSGCPEAEEPANLESFGGEDPRPELQATADLLSSLEDLELSNR 174
ELEEE A + L +R G E L R EL A+ +++ E
Sbjct: 756 ELEEERAGRKGLEARLQQLGEAHQAETEVL--------RREL---AEAMAAQHTAESECE 804
Query: 175 RLVGENAKLQRSMETAEEGSARLG----EEILALRKQLHSTQQALQFAKAMDEELEDLKT 230
+LV E A + E +++ A+ G E+++ L+++ +Q LQ AK +E
Sbjct: 805 QLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSE 864
Query: 231 LARSLEEQNRS--------LLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQ 282
L S ++ + L Q ++ E Q L ++ TLQE+ E ++ +
Sbjct: 865 LQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVR 924
Query: 283 ELAMEKDTLKRQLFECEHLICQR--DTILSERTRDVESLAQTLEEYRVTTQELRLEISRL 340
+ +++T R+L + R + + ++ R S L+ +++ E+ RL
Sbjct: 925 KAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERL 984
Query: 341 EEQLSQTYEGPDELPEGAQLRRV 363
L ++ +G + G Q R V
Sbjct: 985 RAALMES-QGQQQEERGQQEREV 1006
Score = 39.7 bits (91), Expect = 0.007
Identities = 61/241 (25%), Positives = 111/241 (46%), Gaps = 42/241 (17%)
Query: 160 ADLLSSLEDLELS---NRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQ 216
AD S+ ++LEL NR+L+ E M+ + A L E+ Q
Sbjct: 224 ADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEK---------------Q 268
Query: 217 FAKAMD-EELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERD 275
A ++ +ELE+L+ SL + L Q + + E+ + ++ L EENG L +
Sbjct: 269 AASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFK-- 326
Query: 276 GVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQE--- 332
+++ + L +D L +L E EH ++ L ++ + + L+ L++ + ++
Sbjct: 327 -LREFASHLQQLQDAL-NELTE-EHSKATQEW-LEKQAQLEKELSAALQDKKCLEEKNEI 382
Query: 333 LRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQEVATADLS 392
L+ ++S+LEE LSQ + P + +G L V L++E + KQE AT +
Sbjct: 383 LQGKLSQLEEHLSQLQDNPPQ-EKGEVLGDV-----------LQLETL--KQEAATLAAN 428
Query: 393 N 393
N
Sbjct: 429 N 429
Score = 39.3 bits (90), Expect = 0.010
Identities = 53/257 (20%), Positives = 94/257 (36%), Gaps = 19/257 (7%)
Query: 116 LEEETAFQGALTSRQLPSGCPEAEEPAN---------LESFG------GEDPRPELQATA 160
LEE+ Q T L + EAE+ N +ES G G+ R + T
Sbjct: 952 LEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQ 1011
Query: 161 DLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKA 220
+ + DL L +LQ ++ A L E + + Q L +
Sbjct: 1012 ERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRG 1071
Query: 221 MD----EELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDG 276
++ +ELE+L+ + L+EQ + Q E + L AE
Sbjct: 1072 LEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSK 1131
Query: 277 VKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLE 336
++++ Q+ + D+L+R L +RD+ L +E AQ L + + E
Sbjct: 1132 LEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRE 1191
Query: 337 ISRLEEQLSQTYEGPDE 353
++ ++ + DE
Sbjct: 1192 LAAFRTKVQDHSKAEDE 1208
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 54.3 bits (129), Expect = 3e-07
Identities = 56/232 (24%), Positives = 98/232 (42%), Gaps = 34/232 (14%)
Query: 157 QATADLLSSLE-------DLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH 209
Q DL SLE D E + R+L G+ Q S+ A + +L E++ +L
Sbjct: 1078 QQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELS 1137
Query: 210 STQQALQ----FAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETL-- 263
++ M +++++L+ A LEE+ + A + EK++ E+E L
Sbjct: 1138 QLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSE 1197
Query: 264 --QEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLIC----QRDTILSERTRDVE 317
+E G +R+G +KR EL + L+ E + ++ +E V+
Sbjct: 1198 RLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVD 1257
Query: 318 SLAQTLEEYRVTTQELRLEISRL-------------EEQLSQTYEGPDELPE 356
SL + ++ ELR+E+ L E+L +TYE D+L E
Sbjct: 1258 SLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYE--DQLSE 1307
Score = 50.8 bits (120), Expect = 3e-06
Identities = 67/262 (25%), Positives = 112/262 (42%), Gaps = 34/262 (12%)
Query: 115 ELEEETAFQGALTS--RQLPSGCP--------EAEEPANLESF----GGEDPRPELQATA 160
+LEEE+ + AL + L C EAE A L+ E + + A
Sbjct: 1367 QLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEA 1426
Query: 161 DLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGE-EILALRKQLHSTQQALQFAK 219
D + E+LE + ++L +LQ + E E +A+ E LR Q S L
Sbjct: 1427 DAIQRTEELEEAKKKLA---LRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTL---- 1479
Query: 220 AMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKK 279
ELE + A +L+++ R L + ++++ + E+E Q E+ L E ++
Sbjct: 1480 ----ELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRH 1535
Query: 280 RSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISR 339
+E +TLKR E+ Q + +S+ T V ++++E T + L E S
Sbjct: 1536 GHEEALEALETLKR-----ENKNLQEE--ISDLTDQVSLSGKSIQELEKTKKALEGEKSE 1588
Query: 340 LEEQLSQTYEGPDELPEGAQLR 361
++ L + EG EL E LR
Sbjct: 1589 IQAALEEA-EGALELEETKTLR 1609
Score = 47.4 bits (111), Expect = 4e-05
Identities = 77/323 (23%), Positives = 132/323 (40%), Gaps = 23/323 (7%)
Query: 31 SLEEQILNSTFEACDPQRTGTVAVAQVLAYLEAVTGQGPQDARLQTLANSLDPNGEGPKA 90
+L+E + T E Q A+ + A + V+ RL+ L+ + E K
Sbjct: 1033 ALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKK 1092
Query: 91 TVDLDTFLVVMRDWIAACQLHGGLELEEETAFQGALTSRQLPSGCPEAEEPANLESFGGE 150
+ +DT A +L G L+L +E+ A +QL + + + S E
Sbjct: 1093 -LRMDTER-------AKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVE 1144
Query: 151 DPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHS 210
D E A + +++L+ L E + + E+ A E+ L ++L
Sbjct: 1145 D---EQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEE 1201
Query: 211 TQQALQFAKAMDEELE-DLKTLARSLEE---QNRSLLAQARQAEKE-QQHLVAEMETLQE 265
A + + E +L L R LEE ++ + +A R+ + E L ++++LQ
Sbjct: 1202 AGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQR 1261
Query: 266 ENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEE 325
KL E+ ++ +LA +TL R E L + LSE VE L + L +
Sbjct: 1262 VRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLAD 1321
Query: 326 YRVTTQELRL-----EISRLEEQ 343
+TQ RL E+SRL E+
Sbjct: 1322 --ASTQRGRLQTESGELSRLLEE 1342
Score = 43.5 bits (101), Expect = 5e-04
Identities = 41/184 (22%), Positives = 80/184 (43%), Gaps = 12/184 (6%)
Query: 181 AKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNR 240
A+L + E ++ L E+ LR L +++ + A ++EL + L QN
Sbjct: 1714 AELHEQAQALERRASLLAAELEELRAALEQGERSRRLA---EQELLEATERLNLLHSQNT 1770
Query: 241 SLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEH 300
LL Q ++ E + L E+E +E + + KK + AM + LK++ H
Sbjct: 1771 GLLNQKKKLEADLAQLSGEVEEAAQERRE---AEEKAKKAITDAAMMAEELKKEQDTSAH 1827
Query: 301 LICQRDTILSERTRDVESLAQTLEEY-----RVTTQELRLEISRLEEQLSQTYEGPDELP 355
L + T L + R++++ + E+ + Q+L ++ LE +L + E
Sbjct: 1828 LERMKKT-LEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEAL 1886
Query: 356 EGAQ 359
+G +
Sbjct: 1887 KGVR 1890
Score = 43.1 bits (100), Expect = 7e-04
Identities = 41/181 (22%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Query: 162 LLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAM 221
LL+ + LE +L GE + + AEE + + + + ++L Q + M
Sbjct: 1772 LLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1831
Query: 222 DEELED-LKTLARSLEEQNRSLLA----QARQAEKEQQHLVAEMETLQEENGKLLAERDG 276
+ LE ++ L LEE ++ L Q ++ E + + L AE++ Q+++ + L
Sbjct: 1832 KKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRK 1891
Query: 277 VKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQ----TLEEYRVTTQE 332
++R +ELA + + ++ L + L+ + + + R E Q L +YR E
Sbjct: 1892 HERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHE 1951
Query: 333 L 333
L
Sbjct: 1952 L 1952
Score = 40.0 bits (92), Expect = 0.006
Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 20/161 (12%)
Query: 194 SARLGEEILALRKQLHSTQQALQFAKAMDEELEDL--------KTLARSL---------- 235
SA+ EE+ ALR +L + AL A+A +ELE+ LA L
Sbjct: 891 SAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADA 950
Query: 236 EEQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQL 295
EE+ L+ Q E + + L +E +E N L A R ++ EL + D LK L
Sbjct: 951 EERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTL 1010
Query: 296 FECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLE 336
+ E + + T ++ +L +++ R+T ++ L+
Sbjct: 1011 AKAEKEKQATENKVKNLTEEMAALDESVA--RLTKEKKALQ 1049
Score = 35.4 bits (80), Expect = 0.14
Identities = 78/336 (23%), Positives = 124/336 (36%), Gaps = 38/336 (11%)
Query: 114 LELEEETAFQGALTSRQ--LPSGCPEAE----------EPANLESFG-GEDPRPELQATA 160
LELE T+ AL +Q L E E A ES G G +
Sbjct: 1479 LELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHE 1538
Query: 161 DLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKA 220
+ L +LE L+ N+ L E + L + + + L + AL + Q AL+ A+
Sbjct: 1539 EALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEG 1598
Query: 221 MDEELEDLKTLARSLEEQNRSLLAQARQAEKEQ---------QHLVAEMETLQEENGKLL 271
ELE+ KTL LE + AEK++ Q V ++ + +
Sbjct: 1599 A-LELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRAR 1657
Query: 272 AERDGVKKRSQ----ELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYR 327
E +KK+ + +L ++ RQ E + L E + + E
Sbjct: 1658 NEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELH 1717
Query: 328 VTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEI-----EAIRQ 382
Q L S L +L + L +G + RR+ ELL + L + +
Sbjct: 1718 EQAQALERRASLLAAELEELRAA---LEQGERSRRLAEQELLEATERLNLLHSQNTGLLN 1774
Query: 383 KQEVATADLSNPLCGVWQWEEVIHETSEETEFPSEA 418
+++ ADL+ L G + EE E E E +A
Sbjct: 1775 QKKKLEADLAQ-LSG--EVEEAAQERREAEEKAKKA 1807
Score = 29.6 bits (65), Expect = 7.7
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 13/122 (10%)
Query: 243 LAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQL------- 295
L ++ QAE+E L AE+ L+ A+R +++ + EK+ L QL
Sbjct: 888 LLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNL 947
Query: 296 ---FECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPD 352
E HL+ + L + V+ L++ LE+ +L +LE++ ++ + D
Sbjct: 948 ADAEERCHLLIKSKVQLEGK---VKELSERLEDEEEVNADLAARRRKLEDECTELKKDID 1004
Query: 353 EL 354
+L
Sbjct: 1005 DL 1006
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 53.9 bits (128), Expect = 4e-07
Identities = 82/348 (23%), Positives = 150/348 (43%), Gaps = 69/348 (19%)
Query: 145 ESFGGEDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILAL 204
+S ++ +PELQ L+ + L+ V E +LQ+ E + A+ +++L
Sbjct: 139 QSVHHQELKPELQ----LMHQQQQLQPQQ---VQEQQRLQQQQEQLQTQQAQ-EQQVLQQ 190
Query: 205 RKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQ 264
++QL Q Q + E+L+ + L + + Q + Q Q +++QQ L L
Sbjct: 191 QEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLL------LL 244
Query: 265 EENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLE 324
++ G+L + Q L ++ L++QL E + Q+ +L ++ E L Q +
Sbjct: 245 QQQGQL---------QQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQ----EQLQQQQQ 291
Query: 325 EYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQKQ 384
+ + Q+ +L+ ++QL P+E E +L EL+P LG E E +Q+Q
Sbjct: 292 QQLLQQQQEQLQ----QQQLQPPPLEPEE-EEEVEL------ELMPVDLGSEQELEQQRQ 340
Query: 385 EVATADLSNPLCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQGEPAHPEEGRKEPSMWL 444
E+ E +E E E QR Q + + ++
Sbjct: 341 EL--------------------ERQQELERQQE-----QRQLQLKLQEELQQLEQQLEQQ 375
Query: 445 TRREEEEDAESQVTADLPVPLGAPRPGDIPENPPERPARRELQQALVP 492
++ E+++ + ++T PV LGA + E P +P ELQ LVP
Sbjct: 376 QQQLEQQEVQLELT---PVELGAQQQEVQLELTPVQP---ELQLELVP 417
>gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 1 [Homo sapiens]
Length = 953
Score = 53.9 bits (128), Expect = 4e-07
Identities = 67/275 (24%), Positives = 111/275 (40%), Gaps = 45/275 (16%)
Query: 155 ELQATADLLSSLE-DLELSNR---RLVGENAKLQRSMETAEEGSARLGEEILALRKQLHS 210
++ A LL E DLEL+ R L+ +N L E EE + EE+ LR +L
Sbjct: 111 DIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSM 170
Query: 211 TQQALQFAKAMDEE-------------------------LEDLKTLARSLEEQNRSLLAQ 245
+ LQF + EE L+ L+ + LEE+N L ++
Sbjct: 171 KDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSE 230
Query: 246 ARQA--------EKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFE 297
A Q EKEQQ + ++ L++ N ++ + + + K++++ A +++ + L +
Sbjct: 231 ASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQ 290
Query: 298 CEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPE- 356
L + E V+ L + R T ELR + E + +E +EL
Sbjct: 291 IVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNL 350
Query: 357 ------GAQLRRVGWTELLP-PSLGLEIEAIRQKQ 384
RR L P SL EIE +K+
Sbjct: 351 RNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKE 385
Score = 34.7 bits (78), Expect = 0.24
Identities = 55/282 (19%), Positives = 113/282 (40%), Gaps = 30/282 (10%)
Query: 150 EDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARL---GEEILALRK 206
E+ P + AD + + + + L+ +A + + E EE E + + K
Sbjct: 48 EEQLPHYKLRADTIYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTK 107
Query: 207 QLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEMETLQEE 266
+ + + + +LE + +SL ++N++L + E++ +H+ E+ L+ E
Sbjct: 108 TYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHE 167
Query: 267 ---NGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTL 323
+LL + S+ ++ LKR + + ++SL + L
Sbjct: 168 LSMKDELLQFYTSAAEESEPESVCSTPLKR----------NESSSSVQNYFHLDSLQKKL 217
Query: 324 EEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEAIRQK 383
++ LR E S+L+ + + TYE ++ QL EL ++I +I ++
Sbjct: 218 KDLEEENVVLRSEASQLKTE-TITYEEKEQ-----QLVNDCVKEL--RDANVQIASISEE 269
Query: 384 QEVATADLSNPLCGVWQWEEVIHETSEETEFPSEAPAGGQRN 425
T D + Q EE+ H S+ + +A A N
Sbjct: 270 LAKKTEDAAR------QQEEITHLLSQIVDLQKKAKACAVEN 305
Score = 30.0 bits (66), Expect = 5.9
Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 150 EDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH 209
ED + + LLS + DL+ + EN +L + + A++ +L E+ L +
Sbjct: 275 EDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYA 334
Query: 210 STQQALQFAKAMDEELEDL--KTLARSLEEQNRSL 242
+ L A+ EEL++L KT+ + + SL
Sbjct: 335 ECMEMLHEAQ---EELKNLRNKTMPNTTSRRYHSL 366
>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 2 [Homo sapiens]
Length = 686
Score = 53.9 bits (128), Expect = 4e-07
Identities = 67/275 (24%), Positives = 111/275 (40%), Gaps = 45/275 (16%)
Query: 155 ELQATADLLSSLE-DLELSNR---RLVGENAKLQRSMETAEEGSARLGEEILALRKQLHS 210
++ A LL E DLEL+ R L+ +N L E EE + EE+ LR +L
Sbjct: 53 DIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSM 112
Query: 211 TQQALQFAKAMDEE-------------------------LEDLKTLARSLEEQNRSLLAQ 245
+ LQF + EE L+ L+ + LEE+N L ++
Sbjct: 113 KDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSE 172
Query: 246 ARQA--------EKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFE 297
A Q EKEQQ + ++ L++ N ++ + + + K++++ A +++ + L +
Sbjct: 173 ASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQ 232
Query: 298 CEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPE- 356
L + E V+ L + R T ELR + E + +E +EL
Sbjct: 233 IVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNL 292
Query: 357 ------GAQLRRVGWTELLP-PSLGLEIEAIRQKQ 384
RR L P SL EIE +K+
Sbjct: 293 RNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKE 327
Score = 30.0 bits (66), Expect = 5.9
Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 150 EDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH 209
ED + + LLS + DL+ + EN +L + + A++ +L E+ L +
Sbjct: 217 EDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYA 276
Query: 210 STQQALQFAKAMDEELEDL--KTLARSLEEQNRSL 242
+ L A+ EEL++L KT+ + + SL
Sbjct: 277 ECMEMLHEAQ---EELKNLRNKTMPNTTSRRYHSL 308
Score = 29.6 bits (65), Expect = 7.7
Identities = 46/230 (20%), Positives = 94/230 (40%), Gaps = 27/230 (11%)
Query: 199 EEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVA 258
E + + K + + + + +LE + +SL ++N++L + E++ +H+
Sbjct: 42 ERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIRE 101
Query: 259 EMETLQEE---NGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRD 315
E+ L+ E +LL + S+ ++ LKR + +
Sbjct: 102 EVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKR----------NESSSSVQNYFH 151
Query: 316 VESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGL 375
++SL + L++ LR E S+L+ + + TYE ++ QL EL +
Sbjct: 152 LDSLQKKLKDLEEENVVLRSEASQLKTE-TITYEEKEQ-----QLVNDCVKEL--RDANV 203
Query: 376 EIEAIRQKQEVATADLSNPLCGVWQWEEVIHETSEETEFPSEAPAGGQRN 425
+I +I ++ T D + Q EE+ H S+ + +A A N
Sbjct: 204 QIASISEELAKKTEDAAR------QQEEITHLLSQIVDLQKKAKACAVEN 247
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 53.5 bits (127), Expect = 5e-07
Identities = 59/325 (18%), Positives = 137/325 (42%), Gaps = 31/325 (9%)
Query: 152 PRPELQATAD------------LLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGE 199
P+ +LQA AD L + +E+ EL NR + K+ R E +E ++ E
Sbjct: 247 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQE 306
Query: 200 EILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEK-------- 251
+ +R+Q ++ + +E++ + + EE+ R L + + EK
Sbjct: 307 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 366
Query: 252 EQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQ---LFECEHLICQRDTI 308
+++ + E E QE+ K+ + + ++++ +++ +++ ++ Q + E E + +++
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 309 LSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTEL 368
+ E+ + + + E +E +I EE + + E E EG + +
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE-QEGKMCEQEAKMQE 485
Query: 369 LPPSLGLEIEAIRQKQEVATADLSNPLCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQG 428
+ + E IR++++ + + EE++ E E+ E + Q
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEK----IREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 429 EP---AHPEEGRKEPSMWLTRREEE 450
+ EE +E + L ++EE+
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/314 (19%), Positives = 127/314 (40%), Gaps = 23/314 (7%)
Query: 154 PELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQ 213
PE + S ++ + S++ +L+ ++T + + E +AL H+ +Q
Sbjct: 84 PETTTSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQ 143
Query: 214 ALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHLVAEM------------- 260
A+ + L D A LE+ ++ Q ++A++ + L E
Sbjct: 144 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 203
Query: 261 -ETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESL 319
E L+E+N KL + V+ E+ + LKR+L + L+ Q+ + + + L
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-----QLQAEADHL 258
Query: 320 AQTLEEYRVTTQELRLEISRLEEQLSQTYEGPDELPEGAQLRRVGWTELLPPSLGLEIEA 379
+ L+ Q ++E + L +L+Q E E R + + + E
Sbjct: 259 GKELQSVSAKLQ-AQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEK 317
Query: 380 IRQKQEV---ATADLSNPLCGVWQWEEVIHETSEETEFPSEAPAGGQRNFQGEPAHPEEG 436
+R+++E+ + +W+ EE I E E+ + ++ + E +E
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 377
Query: 437 RKEPSMWLTRREEE 450
R+E + R+EE+
Sbjct: 378 RQEQEAKMWRQEEK 391
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,082,457
Number of Sequences: 37866
Number of extensions: 1360948
Number of successful extensions: 10304
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 275
Number of HSP's successfully gapped in prelim test: 833
Number of HSP's that attempted gapping in prelim test: 6099
Number of HSP's gapped (non-prelim): 3252
length of query: 562
length of database: 18,247,518
effective HSP length: 107
effective length of query: 455
effective length of database: 14,195,856
effective search space: 6459114480
effective search space used: 6459114480
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.