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Search of human proteins with 117190334
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117190334 PHD finger protein 16 [Homo sapiens]
(823 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117190334 PHD finger protein 16 [Homo sapiens] 1704 0.0
gi|7662006 PHD finger protein 16 [Homo sapiens] 1704 0.0
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens] 681 0.0
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens] 630 e-180
gi|40556370 PHD finger protein 15 [Homo sapiens] 607 e-173
gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 224 3e-58
gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 224 3e-58
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 218 1e-56
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 210 4e-54
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 139 8e-33
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 139 8e-33
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 137 5e-32
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 127 4e-29
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 127 4e-29
gi|45504380 jumonji domain containing 2B [Homo sapiens] 104 4e-22
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 102 2e-21
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 102 2e-21
gi|98986459 jumonji domain containing 2A [Homo sapiens] 93 9e-19
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 69 2e-11
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 69 2e-11
gi|4505777 PHD finger protein 1 isoform a [Homo sapiens] 54 5e-07
gi|13435397 PHD finger protein 1 isoform b [Homo sapiens] 54 5e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 52 2e-06
gi|6678764 metal response element binding transcription factor 2... 52 2e-06
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 46 1e-04
gi|194328736 PHD finger protein 10 isoform b [Homo sapiens] 46 1e-04
gi|194328734 PHD finger protein 10 isoform a [Homo sapiens] 46 1e-04
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 45 3e-04
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 45 3e-04
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 45 3e-04
>gi|117190334 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 1704 bits (4414), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MKRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPDSHHI 60
MKRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPDSHHI
Sbjct: 1 MKRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPDSHHI 60
Query: 61 NPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDT 120
NPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDT
Sbjct: 61 NPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDT 120
Query: 121 TEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCH 180
TEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCH
Sbjct: 121 TEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCH 180
Query: 181 ENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEG 240
ENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEG
Sbjct: 181 ENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEG 240
Query: 241 SWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKI 300
SWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKI
Sbjct: 241 SWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKI 300
Query: 301 SHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKS 360
SHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKS
Sbjct: 301 SHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKS 360
Query: 361 YCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAEL 420
YCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAEL
Sbjct: 361 YCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAEL 420
Query: 421 GMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLE 480
GMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLE
Sbjct: 421 GMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLE 480
Query: 481 RVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRIT 540
RVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRIT
Sbjct: 481 RVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRIT 540
Query: 541 LKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMRTKSYPRYPLES 600
LKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMRTKSYPRYPLES
Sbjct: 541 LKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMRTKSYPRYPLES 600
Query: 601 KNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPN 660
KNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPN
Sbjct: 601 KNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPN 660
Query: 661 SKFAKSNGLEGSWSGNVTQKDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETT 720
SKFAKSNGLEGSWSGNVTQKDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETT
Sbjct: 661 SKFAKSNGLEGSWSGNVTQKDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETT 720
Query: 721 NRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCPDLELSDSEAES 780
NRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCPDLELSDSEAES
Sbjct: 721 NRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCPDLELSDSEAES 780
Query: 781 DGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR 823
DGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR
Sbjct: 781 DGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR 823
>gi|7662006 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 1704 bits (4414), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MKRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPDSHHI 60
MKRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPDSHHI
Sbjct: 1 MKRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPDSHHI 60
Query: 61 NPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDT 120
NPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDT
Sbjct: 61 NPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDT 120
Query: 121 TEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCH 180
TEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCH
Sbjct: 121 TEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCH 180
Query: 181 ENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEG 240
ENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEG
Sbjct: 181 ENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEG 240
Query: 241 SWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKI 300
SWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKI
Sbjct: 241 SWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKI 300
Query: 301 SHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKS 360
SHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKS
Sbjct: 301 SHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKS 360
Query: 361 YCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAEL 420
YCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAEL
Sbjct: 361 YCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAEL 420
Query: 421 GMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLE 480
GMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLE
Sbjct: 421 GMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLE 480
Query: 481 RVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRIT 540
RVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRIT
Sbjct: 481 RVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRIT 540
Query: 541 LKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMRTKSYPRYPLES 600
LKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMRTKSYPRYPLES
Sbjct: 541 LKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMRTKSYPRYPLES 600
Query: 601 KNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPN 660
KNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPN
Sbjct: 601 KNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPN 660
Query: 661 SKFAKSNGLEGSWSGNVTQKDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETT 720
SKFAKSNGLEGSWSGNVTQKDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETT
Sbjct: 661 SKFAKSNGLEGSWSGNVTQKDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETT 720
Query: 721 NRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCPDLELSDSEAES 780
NRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCPDLELSDSEAES
Sbjct: 721 NRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCPDLELSDSEAES 780
Query: 781 DGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR 823
DGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR
Sbjct: 781 DGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR 823
>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
Length = 842
Score = 681 bits (1756), Expect = 0.0
Identities = 331/563 (58%), Positives = 421/563 (74%), Gaps = 25/563 (4%)
Query: 1 MKRHRPVSSSDSSDESPSTSFT----SGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPD 56
MKR R SSS+ SD++ S S T S S +R S +E +KP+EVFR DLI+AMKL D
Sbjct: 1 MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD 60
Query: 57 SHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCS 116
S+ +NPD YY+ AD W++EWEKGVQVP SP T+PQP R+++E+ K ++FIRP+KYI S
Sbjct: 61 SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEE-KSLMFIRPKKYIVSS 119
Query: 117 SPDTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLE 176
+ E GY++I LA SVCRYDL+DMD WL+ NE+ EMG +DE ME+ +E E
Sbjct: 120 GSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFE 179
Query: 177 RHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILK 236
+ C++NMNHAIETEEGLGIEYDEDV+CDVC+SPD E+GN+MVFCDKCN+CVHQACYGILK
Sbjct: 180 QRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILK 239
Query: 237 VPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEP 296
VPEGSWLCR+C LG+ P+C+LCPKKGGA+K T++GTKW HVSCALWIPEVSI PE+MEP
Sbjct: 240 VPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEP 299
Query: 297 ITKISHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEV 356
ITK+SHIP SRWALVC+LC K GA IQCS+K+C TAFHVTCAF+ GLEMKTIL E DEV
Sbjct: 300 ITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEV 359
Query: 357 KFKSYCLKHSQNR---QKLGEAEYPHHRAK--------------EQSQAKSEKTSLRAQK 399
KFKSYC KHS +R + LG+ + A EQ++ ++ + S+R QK
Sbjct: 360 KFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQK 419
Query: 400 LRELEEEFYSLVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQ 459
L++LE+EFY+ V + DVA L +P VDF+Y YWKLKRK NFNKPL PK+DEE+ L +
Sbjct: 420 LQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAK 479
Query: 460 PKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEID 519
+++ + R+++F HLRQDLERVRNL YM++RREK+K S K+QEQIF L +LL QE
Sbjct: 480 REQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERV 539
Query: 520 AGLP---LTNALENSLFYPPPRI 539
+G+P +++LEN L + P +
Sbjct: 540 SGVPSSCSSSSLENMLLFNSPSV 562
Score = 35.0 bits (79), Expect = 0.28
Identities = 14/22 (63%), Positives = 18/22 (81%)
Query: 763 ENDGYCPDLELSDSEAESDGNK 784
ENDGY PD+E+SDSE+E+ K
Sbjct: 799 ENDGYVPDVEMSDSESEASEKK 820
>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
Length = 509
Score = 630 bits (1625), Expect = e-180
Identities = 302/503 (60%), Positives = 380/503 (75%), Gaps = 22/503 (4%)
Query: 1 MKRHRPVSSSDSSDESPSTSFT----SGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPD 56
MKR R SSS+ SD++ S S T S S +R S +E +KP+EVFR DLI+AMKL D
Sbjct: 1 MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD 60
Query: 57 SHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCS 116
S+ +NPD YY+ AD W++EWEKGVQVP SP T+PQP R+++E+ K ++FIRP+KYI S
Sbjct: 61 SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEE-KSLMFIRPKKYIVSS 119
Query: 117 SPDTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLE 176
+ E GY++I LA SVCRYDL+DMD WL+ NE+ EMG +DE ME+ +E E
Sbjct: 120 GSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFE 179
Query: 177 RHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILK 236
+ C++NMNHAIETEEGLGIEYDEDV+CDVC+SPD E+GN+MVFCDKCN+CVHQACYGILK
Sbjct: 180 QRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILK 239
Query: 237 VPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEP 296
VPEGSWLCR+C LG+ P+C+LCPKKGGA+K T++GTKW HVSCALWIPEVSI PE+MEP
Sbjct: 240 VPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEP 299
Query: 297 ITKISHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEV 356
ITK+SHIP SRWALVC+LC K GA IQCS+K+C TAFHVTCAF+ GLEMKTIL E DEV
Sbjct: 300 ITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEV 359
Query: 357 KFKSYCLKHSQNR---QKLGEAEYPHHRAK--------------EQSQAKSEKTSLRAQK 399
KFKSYC KHS +R + LG+ + A EQ++ ++ + S+R QK
Sbjct: 360 KFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQK 419
Query: 400 LRELEEEFYSLVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQ 459
L++LE+EFY+ V + DVA L +P VDF+Y YWKLKRK NFNKPL PK+DEE+ L +
Sbjct: 420 LQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAK 479
Query: 460 PKEESIHTRMRMFMHLRQDLERV 482
+++ + R+++F HLRQDLERV
Sbjct: 480 REQDVLFRRLQLFTHLRQDLERV 502
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 607 bits (1565), Expect = e-173
Identities = 299/543 (55%), Positives = 384/543 (70%), Gaps = 27/543 (4%)
Query: 2 KRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNE---------HKKPAEVFRKDLISAM 52
KR + SSD+SD + S + TS S R SK+P+ KKP+EVFR DLI+AM
Sbjct: 4 KRRKYSISSDNSDTTDSHA-TSTSASRC-SKLPSSTKSGWPRQNEKKPSEVFRTDLITAM 61
Query: 53 KLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKY 112
K+PDS+ ++PD YY+ AD W++EWEKGVQVPA + +P+P +RI+ P
Sbjct: 62 KIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSST 121
Query: 113 IHCSSPDTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTV 172
+ PG RYDLD++D +WL+ +N +L EM +DE +E+ +
Sbjct: 122 MLGEGSQPDWPGG----------SRYDLDEIDAYWLELINSELKEMERPELDELTLERVL 171
Query: 173 EVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACY 232
E LE CH+NM AIET+EGLGIEYDEDV+CDVCRSP+ E+GN+MVFCDKCNVCVHQACY
Sbjct: 172 EELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACY 231
Query: 233 GILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPE 292
GILKVP GSWLCR+C LG+ P+C+LCPK+GGALK T++GTKW HVSCALWIPEVSI CPE
Sbjct: 232 GILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPE 291
Query: 293 RMEPITKISHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDE 352
+MEPITKISHIP SRWAL C+LCK TG CIQCS+ SC+TAFHVTCAF+HGLEM+TIL +
Sbjct: 292 KMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILAD 351
Query: 353 GDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKS--EKTSLRAQKLRELEEEFYSL 410
DEVKFKS+C +HS G P E SQA EK +LR Q+L++LEE+FY L
Sbjct: 352 NDEVKFKSFCQEHSDG----GPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYEL 407
Query: 411 VRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMR 470
V +VA L + VDFIY YWKLKRK+N N+PL PK DE + L Q +++ ++ R++
Sbjct: 408 VEPAEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLK 467
Query: 471 MFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALEN 530
+F HLRQDLERVRNLCYM++RRE+ K + K+QEQIF LQ++L+ Q++ GL + ++
Sbjct: 468 LFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRGLSTSFPIDG 527
Query: 531 SLF 533
+ F
Sbjct: 528 TFF 530
>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform
2 [Homo sapiens]
Length = 1214
Score = 224 bits (570), Expect = 3e-58
Identities = 138/421 (32%), Positives = 208/421 (49%), Gaps = 52/421 (12%)
Query: 138 YDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEY 197
YD+D+ D WL +NE G P+ + + E ++ LE+ + ++ + +
Sbjct: 215 YDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALV---- 270
Query: 198 DEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVL--GIYPQC 255
DED +C +C + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C
Sbjct: 271 DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDC 330
Query: 256 VLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC 315
LCP KGGA K T G +WAHV CALWIPEV A +EPI I HIPP+RW L C +C
Sbjct: 331 ALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYIC 389
Query: 316 KLK-TGACIQCSIKSCITAFHVTCAFEHGLEMK--TILDEGD-----EVKFKSYC----- 362
K + +GACIQC +C TAFHVTCA + GL MK + + G V+ +YC
Sbjct: 390 KQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTP 449
Query: 363 ---------LKHSQNRQKLGEAEYPHHR-AKEQSQAKSEKTSLRAQKLRELEEEFYSLVR 412
L HS+ + E E + E+ + K+ ++ +K R++ E +
Sbjct: 450 PGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAP 509
Query: 413 VEDVAA-------------ELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKE-------- 451
V V + + + +++YW LKR+S PL +
Sbjct: 510 VVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRN 569
Query: 452 -DEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQ 510
D+ + K ++ +++ + LR DLER R L +I +REKLK K+Q+ +Q
Sbjct: 570 CDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQ 629
Query: 511 V 511
+
Sbjct: 630 L 630
>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform
1 [Homo sapiens]
Length = 1220
Score = 224 bits (570), Expect = 3e-58
Identities = 138/421 (32%), Positives = 208/421 (49%), Gaps = 52/421 (12%)
Query: 138 YDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEY 197
YD+D+ D WL +NE G P+ + + E ++ LE+ + ++ + +
Sbjct: 215 YDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALV---- 270
Query: 198 DEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVL--GIYPQC 255
DED +C +C + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C
Sbjct: 271 DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDC 330
Query: 256 VLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC 315
LCP KGGA K T G +WAHV CALWIPEV A +EPI I HIPP+RW L C +C
Sbjct: 331 ALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYIC 389
Query: 316 KLK-TGACIQCSIKSCITAFHVTCAFEHGLEMK--TILDEGD-----EVKFKSYC----- 362
K + +GACIQC +C TAFHVTCA + GL MK + + G V+ +YC
Sbjct: 390 KQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTP 449
Query: 363 ---------LKHSQNRQKLGEAEYPHHR-AKEQSQAKSEKTSLRAQKLRELEEEFYSLVR 412
L HS+ + E E + E+ + K+ ++ +K R++ E +
Sbjct: 450 PGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAP 509
Query: 413 VEDVAA-------------ELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKE-------- 451
V V + + + +++YW LKR+S PL +
Sbjct: 510 VVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRN 569
Query: 452 -DEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQ 510
D+ + K ++ +++ + LR DLER R L +I +REKLK K+Q+ +Q
Sbjct: 570 CDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQ 629
Query: 511 V 511
+
Sbjct: 630 L 630
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 218 bits (556), Expect = 1e-56
Identities = 153/474 (32%), Positives = 234/474 (49%), Gaps = 65/474 (13%)
Query: 83 PASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAA----SVCRY 138
PAS +P+P +RI+ +Y S+P P Y +E +A + Y
Sbjct: 111 PASASALPEPKVRIV-------------EYSPPSAP-RRPPVYYKFIEKSAEELDNEVEY 156
Query: 139 DLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCH-ENMNHAIETEEGLGIEY 197
D+D+ D WL+ +NE V +++ E ++ E+ H EN ++ L
Sbjct: 157 DMDEEDYAWLEIVNEKRKGDCVPAVSQSMFEFLMDRFEKESHCENQKQG--EQQSL---I 211
Query: 198 DEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLGIY--PQC 255
DED +C +C + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C
Sbjct: 212 DEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADC 271
Query: 256 VLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC 315
VLCP KGGA K T +W HV CALWIPEV A +EPI + +IPP+RW L C LC
Sbjct: 272 VLCPNKGGAFKKT-DDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLC 330
Query: 316 KLK-TGACIQCSIKSCITAFHVTCAFEHGLEMK----TILDEGD---EVKFKSYCLKHSQ 367
K K GACIQC +C TAFHVTCA + GL MK L G V+ +YC H+
Sbjct: 331 KQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGGTTFSVRKTAYCDVHTP 390
Query: 368 ---NRQKL---GEAEYPHHRAKEQSQAK----SEKTSLRAQKLRELEEEFYSLV------ 411
R+ L G+ E + +++S K + K +A+K ++ E +++
Sbjct: 391 PGCTRRPLNIYGDVEMKNGVCRKESSVKTVRSTSKVRKKAKKAKKALAEPCAVLPTVCAP 450
Query: 412 -----RVEDVAAELGMPTLA--VDFIYNYWKLKRKSNFNKPLF----PPKEDEENGLVQP 460
R+ +A ++ + V+ ++YW LKR S PL + + + +
Sbjct: 451 YIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRSSQQRE 510
Query: 461 KEESIHT---RMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQV 511
+E + +++ + LR DLER R L ++ +REKLK K+++ L++
Sbjct: 511 NDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQVAMELRL 564
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
sapiens]
Length = 1205
Score = 210 bits (535), Expect = 4e-54
Identities = 158/519 (30%), Positives = 228/519 (43%), Gaps = 85/519 (16%)
Query: 89 VPQPSLRIIAEKVKDVLFIRPRKYI-HCSSPDTTEPGYINIMELAASVCRYDLDDMDIFW 147
+PQPS R++ ++ P Y + P +L A V YD+D+ D+ W
Sbjct: 114 LPQPSFRMVDSGIQPEAPPLPAAYYRYIEKPPE---------DLDAEV-EYDMDEEDLAW 163
Query: 148 LQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCR 207
L +NE G V + E V+ LE+ + + + ++ L DED C VC
Sbjct: 164 LDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLE-SRSSGAQQSL---IDEDAFCCVCL 219
Query: 208 SPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLGIY--PQCVLCPKKGGAL 265
+ N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C+LCP KGGA
Sbjct: 220 DDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAF 279
Query: 266 KTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLK-TGACIQ 324
K T G WAHV CA+WIPEV A +EPI I +IPP+RW L C +CK K GA IQ
Sbjct: 280 KQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQ 338
Query: 325 CSIKSCITAFHVTCAFEHGLEMK-------TILDEGDEVKFKSYCLKHSQN--------- 368
C +C TAFHVTCA GL MK ++ V+ +YC HS
Sbjct: 339 CHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKG 398
Query: 369 ---------------RQKLGEAEYPHHRAKEQSQA------------KSEKTSLRAQKLR 401
++ GE E +E+ +A K K SL+ + +
Sbjct: 399 DSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKK 458
Query: 402 ELEEEFYSLVRVEDVAAELGMPTLAVDFI----------------YNYWKLKRKSNFNKP 445
E EE + A +P+ ++ I +NYW LKR++ P
Sbjct: 459 EPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVP 518
Query: 446 L-------FPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLS 498
L + + E K ++ ++ + LR DLER R L +I +REKLK
Sbjct: 519 LIRRLHSHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKRE 578
Query: 499 HNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPP 537
K+Q+ L++ N + L L + + + P
Sbjct: 579 QVKVQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEP 617
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 139 bits (351), Expect = 8e-33
Identities = 87/218 (39%), Positives = 114/218 (52%), Gaps = 19/218 (8%)
Query: 203 CDVCRSPDSEEGNDMVFCDK--CNVCVHQACYGILKVPEGSWLCRSC---VLGIYPQCVL 257
C VC N +V+CD C+V VHQACYGI++VP G W CR C +C L
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
Query: 258 CPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC-- 315
CP K GALK T G WAHV CAL+IPEV A MEPI + +P R+ C +C
Sbjct: 85 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
Query: 316 -----KLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQ 370
K TGAC+ C+ C AFHVTCA GL + + D V++ YC H
Sbjct: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHF---S 199
Query: 371 KLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFY 408
KL +++ +R+ +QS S+ +S K E E++ Y
Sbjct: 200 KLKKSKRGSNRSYDQS--LSDSSSHSQDKHHEKEKKKY 235
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 139 bits (351), Expect = 8e-33
Identities = 87/218 (39%), Positives = 114/218 (52%), Gaps = 19/218 (8%)
Query: 203 CDVCRSPDSEEGNDMVFCDK--CNVCVHQACYGILKVPEGSWLCRSC---VLGIYPQCVL 257
C VC N +V+CD C+V VHQACYGI++VP G W CR C +C L
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
Query: 258 CPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC-- 315
CP K GALK T G WAHV CAL+IPEV A MEPI + +P R+ C +C
Sbjct: 85 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
Query: 316 -----KLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQ 370
K TGAC+ C+ C AFHVTCA GL + + D V++ YC H
Sbjct: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHF---S 199
Query: 371 KLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFY 408
KL +++ +R+ +QS S+ +S K E E++ Y
Sbjct: 200 KLKKSKRGSNRSYDQS--LSDSSSHSQDKHHEKEKKKY 235
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 137 bits (344), Expect = 5e-32
Identities = 77/175 (44%), Positives = 95/175 (54%), Gaps = 14/175 (8%)
Query: 203 CDVCRSPDSEEGNDMVFCD--KCNVCVHQACYGILKVPEGSWLCRSC---VLGIYPQCVL 257
C VC N +V+CD C+V VHQACYGI++VP G W CR C +C L
Sbjct: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
Query: 258 CPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC-- 315
CP K GALK T G WAHV CAL+IPEV A MEPI + ++P R+ C +C
Sbjct: 68 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEE 125
Query: 316 -----KLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKH 365
K +GAC+ C+ C AFHVTCA GL + + E D VK+ YC H
Sbjct: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 127 bits (319), Expect = 4e-29
Identities = 95/390 (24%), Positives = 167/390 (42%), Gaps = 46/390 (11%)
Query: 164 DENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKC 223
DE L ++ + + +E+ +++ + D +IC VC +SE+ ++++ CD C
Sbjct: 283 DEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNC 342
Query: 224 NVCVHQACYGI--------LKVPEGS---WLCRSCVLGIYPQCVLCPKKGGALKTTKTGT 272
+ VH+ CYG+ E S W C +C G+ P C LCP + G K T G
Sbjct: 343 GITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAG- 401
Query: 273 KWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCK----LKTGACIQCSIK 328
+W H+ CAL++P V+ +++ P+T A C+ C+ +TG CI C
Sbjct: 402 RWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAG 461
Query: 329 SCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHS-------QNRQKLGEAEY---- 377
C FHVTCA + GL + +E F +YC +H+ + + L Y
Sbjct: 462 MCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMS 521
Query: 378 PHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAELGMPTLAVDFIYNYWKLK 437
R K+ S + + R Q+ R + E R + +P KL
Sbjct: 522 LQEREKQLSPEAQARINARLQQYR-AKAELARSTRPQAWVPREKLPRPLTSSASAIRKLM 580
Query: 438 RKS---NFNKPLFPPKEDEENGLVQPKEES-------------IHTRMRMFMHLRQDLER 481
RK+ + +FP + + V + + MRM + +++++
Sbjct: 581 RKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRM-IQIQENMAE 639
Query: 482 VRNLCYMI-SRREKLKLSHNKIQEQIFGLQ 510
+N+ + + +EKL + +NK+ E + LQ
Sbjct: 640 QKNIKDKLENEQEKLHVEYNKLCESLEELQ 669
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 127 bits (319), Expect = 4e-29
Identities = 95/390 (24%), Positives = 167/390 (42%), Gaps = 46/390 (11%)
Query: 164 DENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKC 223
DE L ++ + + +E+ +++ + D +IC VC +SE+ ++++ CD C
Sbjct: 283 DEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNC 342
Query: 224 NVCVHQACYGI--------LKVPEGS---WLCRSCVLGIYPQCVLCPKKGGALKTTKTGT 272
+ VH+ CYG+ E S W C +C G+ P C LCP + G K T G
Sbjct: 343 GITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAG- 401
Query: 273 KWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCK----LKTGACIQCSIK 328
+W H+ CAL++P V+ +++ P+T A C+ C+ +TG CI C
Sbjct: 402 RWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAG 461
Query: 329 SCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHS-------QNRQKLGEAEY---- 377
C FHVTCA + GL + +E F +YC +H+ + + L Y
Sbjct: 462 MCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMS 521
Query: 378 PHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSLVRVEDVAAELGMPTLAVDFIYNYWKLK 437
R K+ S + + R Q+ R + E R + +P KL
Sbjct: 522 LQEREKQLSPEAQARINARLQQYR-AKAELARSTRPQAWVPREKLPRPLTSSASAIRKLM 580
Query: 438 RKS---NFNKPLFPPKEDEENGLVQPKEES-------------IHTRMRMFMHLRQDLER 481
RK+ + +FP + + V + + MRM + +++++
Sbjct: 581 RKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRM-IQIQENMAE 639
Query: 482 VRNLCYMI-SRREKLKLSHNKIQEQIFGLQ 510
+N+ + + +EKL + +NK+ E + LQ
Sbjct: 640 QKNIKDKLENEQEKLHVEYNKLCESLEELQ 669
Score = 32.7 bits (73), Expect = 1.4
Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 7/50 (14%)
Query: 203 CDVCRSPDSEEGNDMVFCDKCNVCVHQACYG--ILKVPEGS---WLCRSC 247
C C+ E ++V CD+C +C H C + K P+ + W+C+ C
Sbjct: 871 CATCKGTGDNE--NLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQEC 918
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 104 bits (259), Expect = 4e-22
Identities = 64/158 (40%), Positives = 84/158 (53%), Gaps = 17/158 (10%)
Query: 217 MVFCDKCNVCVHQACYGILK--VPEGSWLCRSCVLGIYP-QCVLCPKKGGALKTTKTGTK 273
++ C KC + VH +CYGI V EG W C C + +C LC +GGAL+ T T +
Sbjct: 757 LIACGKCCLQVHASCYGIRPELVNEG-WTCSRCAAHAWTAECCLCNLRGGALQMT-TDRR 814
Query: 274 WAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLK----TGACIQCSIKS 329
W HV CA+ +PE P+ IS IP RW L C C+ + +GACIQCS +
Sbjct: 815 WIHVICAIAVPEARFLNVIERHPVD-ISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEH 873
Query: 330 CITAFHVTCAFEHGLEMKTILDEGDEVKF--KSYCLKH 365
C T+FHVTCA G +L E D+ + CLKH
Sbjct: 874 CSTSFHVTCAHAAG-----VLMEPDDWPYVVSITCLKH 906
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 102 bits (253), Expect = 2e-21
Identities = 62/145 (42%), Positives = 82/145 (56%), Gaps = 13/145 (8%)
Query: 212 EEGNDMVF-CDKCNVCVHQACYGIL--KVPEGSWLCRSCVLGIYP-QCVLCPKKGGALKT 267
E+G ++ C KC V VH +CYGI ++ +G WLC C + +C LC +GGALK
Sbjct: 709 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 767
Query: 268 TKTGTKWAHVSCALWIPEVSIA-CPERMEPITKISHIPPSRWALVCNLCKLK----TGAC 322
TK KWAHV CA+ +PEV PER + + IP R L C C+ + +GAC
Sbjct: 768 TKNN-KWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKLKCIFCRHRVKRVSGAC 824
Query: 323 IQCSIKSCITAFHVTCAFEHGLEMK 347
IQCS C +FHVTCA G+ M+
Sbjct: 825 IQCSYGRCPASFHVTCAHAAGVLME 849
Score = 33.5 bits (75), Expect = 0.82
Identities = 39/175 (22%), Positives = 68/175 (38%), Gaps = 35/175 (20%)
Query: 461 KEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDA 520
+EES +RM++ +L ++ N C S E +K +K V ++ E D
Sbjct: 430 EEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAY---RSVPSISSEADD 486
Query: 521 GLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQ 580
+PL++ E K KS P + P SP+S SSV +
Sbjct: 487 SIPLSSGYE--------------KPEKSDPSEL--------SWPKSPESCSSVAESNGVL 524
Query: 581 VPQESLEMRTK-------SYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSS 628
E ++ + P P +N+ + S++ + ++S +WR P S
Sbjct: 525 TEGEESDVESHGNGLEPGEIPAVPSGERNSFKVPSIAEGEN---KTSKSWRHPLS 576
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 102 bits (253), Expect = 2e-21
Identities = 62/145 (42%), Positives = 82/145 (56%), Gaps = 13/145 (8%)
Query: 212 EEGNDMVF-CDKCNVCVHQACYGIL--KVPEGSWLCRSCVLGIYP-QCVLCPKKGGALKT 267
E+G ++ C KC V VH +CYGI ++ +G WLC C + +C LC +GGALK
Sbjct: 709 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 767
Query: 268 TKTGTKWAHVSCALWIPEVSIA-CPERMEPITKISHIPPSRWALVCNLCKLK----TGAC 322
TK KWAHV CA+ +PEV PER + + IP R L C C+ + +GAC
Sbjct: 768 TKNN-KWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKLKCIFCRHRVKRVSGAC 824
Query: 323 IQCSIKSCITAFHVTCAFEHGLEMK 347
IQCS C +FHVTCA G+ M+
Sbjct: 825 IQCSYGRCPASFHVTCAHAAGVLME 849
Score = 33.5 bits (75), Expect = 0.82
Identities = 39/175 (22%), Positives = 68/175 (38%), Gaps = 35/175 (20%)
Query: 461 KEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDA 520
+EES +RM++ +L ++ N C S E +K +K V ++ E D
Sbjct: 430 EEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAY---RSVPSISSEADD 486
Query: 521 GLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQ 580
+PL++ E K KS P + P SP+S SSV +
Sbjct: 487 SIPLSSGYE--------------KPEKSDPSEL--------SWPKSPESCSSVAESNGVL 524
Query: 581 VPQESLEMRTK-------SYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSS 628
E ++ + P P +N+ + S++ + ++S +WR P S
Sbjct: 525 TEGEESDVESHGNGLEPGEIPAVPSGERNSFKVPSIAEGEN---KTSKSWRHPLS 576
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 93.2 bits (230), Expect = 9e-19
Identities = 61/162 (37%), Positives = 83/162 (51%), Gaps = 14/162 (8%)
Query: 212 EEGND-MVFCDKCNVCVHQACYGI--LKVPEGSWLCRSCVLGIYPQ-CVLCPKKGGALKT 267
E+G +V C KC+V VH +CYG+ K E W+C C + C LC +GGAL+
Sbjct: 729 EDGTSILVSCKKCSVRVHASCYGVPPAKASE-DWMCSRCSANALEEDCCLCSLRGGALQR 787
Query: 268 TKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLK----TGACI 323
+W HVSCA+ I E P+ +S IP R+ L C CK + G C+
Sbjct: 788 ANDD-RWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCV 845
Query: 324 QCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKH 365
QCS C TAFHV+CA G+ M+ D+ V F + C +H
Sbjct: 846 QCSHGRCPTAFHVSCAQAAGVMMQP--DDWPFVVFIT-CFRH 884
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 68.9 bits (167), Expect = 2e-11
Identities = 44/104 (42%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 212 EEGNDMVF-CDKCNVCVHQACYGIL--KVPEGSWLCRSCVLGIYP-QCVLCPKKGGALKT 267
E+G ++ C KC V VH +CYGI ++ +G WLC C + +C LC +GGALK
Sbjct: 709 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 767
Query: 268 TKTGTKWAHVSCALWIPEVSIA-CPERMEPITKISHIPPSRWAL 310
TK KWAHV CA+ +PEV PER + + IP R L
Sbjct: 768 TKNN-KWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKL 808
Score = 33.5 bits (75), Expect = 0.82
Identities = 39/175 (22%), Positives = 68/175 (38%), Gaps = 35/175 (20%)
Query: 461 KEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDA 520
+EES +RM++ +L ++ N C S E +K +K V ++ E D
Sbjct: 430 EEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAY---RSVPSISSEADD 486
Query: 521 GLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQ 580
+PL++ E K KS P + P SP+S SSV +
Sbjct: 487 SIPLSSGYE--------------KPEKSDPSEL--------SWPKSPESCSSVAESNGVL 524
Query: 581 VPQESLEMRTK-------SYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSS 628
E ++ + P P +N+ + S++ + ++S +WR P S
Sbjct: 525 TEGEESDVESHGNGLEPGEIPAVPSGERNSFKVPSIAEGEN---KTSKSWRHPLS 576
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 68.9 bits (167), Expect = 2e-11
Identities = 44/104 (42%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 212 EEGNDMVF-CDKCNVCVHQACYGIL--KVPEGSWLCRSCVLGIYP-QCVLCPKKGGALKT 267
E+G ++ C KC V VH +CYGI ++ +G WLC C + +C LC +GGALK
Sbjct: 731 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 789
Query: 268 TKTGTKWAHVSCALWIPEVSIA-CPERMEPITKISHIPPSRWAL 310
TK KWAHV CA+ +PEV PER + + IP R L
Sbjct: 790 TKNN-KWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKL 830
Score = 33.5 bits (75), Expect = 0.82
Identities = 39/175 (22%), Positives = 68/175 (38%), Gaps = 35/175 (20%)
Query: 461 KEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDA 520
+EES +RM++ +L ++ N C S E +K +K V ++ E D
Sbjct: 452 EEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAY---RSVPSISSEADD 508
Query: 521 GLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQ 580
+PL++ E K KS P + P SP+S SSV +
Sbjct: 509 SIPLSSGYE--------------KPEKSDPSEL--------SWPKSPESCSSVAESNGVL 546
Query: 581 VPQESLEMRTK-------SYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSS 628
E ++ + P P +N+ + S++ + ++S +WR P S
Sbjct: 547 TEGEESDVESHGNGLEPGEIPAVPSGERNSFKVPSIAEGEN---KTSKSWRHPLS 598
>gi|4505777 PHD finger protein 1 isoform a [Homo sapiens]
Length = 457
Score = 54.3 bits (129), Expect = 5e-07
Identities = 31/74 (41%), Positives = 41/74 (55%), Gaps = 13/74 (17%)
Query: 199 EDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVP---EG---SWLCRSCVLGIY 252
E+++C VCRS GN +V C+KC HQ C+ + + P EG SW+CR CV I
Sbjct: 86 EELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCH-VPRAPAPGEGEGTSWVCRQCVFAI- 143
Query: 253 PQCVLCPKKGGALK 266
K+GGALK
Sbjct: 144 -----ATKRGGALK 152
>gi|13435397 PHD finger protein 1 isoform b [Homo sapiens]
Length = 567
Score = 54.3 bits (129), Expect = 5e-07
Identities = 31/74 (41%), Positives = 41/74 (55%), Gaps = 13/74 (17%)
Query: 199 EDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVP---EG---SWLCRSCVLGIY 252
E+++C VCRS GN +V C+KC HQ C+ + + P EG SW+CR CV I
Sbjct: 86 EELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCH-VPRAPAPGEGEGTSWVCRQCVFAI- 143
Query: 253 PQCVLCPKKGGALK 266
K+GGALK
Sbjct: 144 -----ATKRGGALK 152
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 52.0 bits (123), Expect = 2e-06
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
Query: 254 QCVLCPKKGGALKTTKTG-------TKWAHVSCALWIPEVSIACPERMEPITKISHIPPS 306
QC LC K G A + + G +W HV+CA+W EV E + K H +
Sbjct: 1580 QCALCLKYGDA-DSKEAGRLLYIGQNEWTHVNCAIWSAEVF----EENDGSLKNVHAAVA 1634
Query: 307 RWALV-CNLCKLKTGACIQCSIKSCITAFHVTCA 339
R + C LC LK GA + C + SC++ FH CA
Sbjct: 1635 RGRQMRCELC-LKPGATVGCCLSSCLSNFHFMCA 1667
>gi|6678764 metal response element binding transcription factor 2
[Homo sapiens]
Length = 593
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 13/73 (17%)
Query: 200 DVICDVCRSPDSEEGNDMVFCDKCNVCVHQACY------GILKVPEGSWLCRSCVLGIYP 253
+++C +C+ SE N+MV CDKC HQ C+ ++ E WLCR CV
Sbjct: 102 EMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDE-KWLCRQCVF---- 156
Query: 254 QCVLCPKKGGALK 266
K+GGALK
Sbjct: 157 --ATTTKRGGALK 167
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 46.2 bits (108), Expect = 1e-04
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 8/89 (8%)
Query: 199 EDVICDVCRSPDSEEGNDMVFCD-KCNVCVHQACYGILKVPEGSWLCRSCVLGIYPQCVL 257
+D +C +C S G+ ++ C+ +C H C G+ +P+ ++C C G +P C
Sbjct: 700 KDTVCQICES----SGDSLIPCEGECCKHFHLECLGLASLPDSKFICMECKTGQHP-CFS 754
Query: 258 CPKKGGALKTTKTGT--KWAHVSCALWIP 284
C G +K G K+ H +C P
Sbjct: 755 CKVSGKDVKRCSVGACGKFYHEACVRKFP 783
Score = 35.8 bits (81), Expect = 0.17
Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 212 EEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLG 250
E+G ++ C+ C H C I ++PEG W C C G
Sbjct: 918 EKGGRLLCCESCPASFHPECLSI-EMPEGCWNCNDCKAG 955
Score = 34.7 bits (78), Expect = 0.37
Identities = 29/106 (27%), Positives = 40/106 (37%), Gaps = 19/106 (17%)
Query: 213 EGNDMVFCDK--CNVCVHQACYGILKVPEGSW-----LCRSCVLGIYPQCVLCPKKGGAL 265
+G ++V CDK C H C + + P G W C C C CP
Sbjct: 1329 DGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWECPWHQCDECSSAAVSFCEFCPH----- 1383
Query: 266 KTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALV 311
K K A V AL E + C E +P+ +S P W+ +
Sbjct: 1384 SFCKDHEKGALVPSAL---EGRLCCSEH-DPMAPVS---PEYWSKI 1422
>gi|194328736 PHD finger protein 10 isoform b [Homo sapiens]
Length = 496
Score = 46.2 bits (108), Expect = 1e-04
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 203 CDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSC 247
C +C P EE +M+FCD C+ H C G+ +P G W+C C
Sbjct: 434 CIICGQPHHEE--EMMFCDMCDRGYHTFCVGLGAIPSGRWICDCC 476
>gi|194328734 PHD finger protein 10 isoform a [Homo sapiens]
Length = 498
Score = 46.2 bits (108), Expect = 1e-04
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 203 CDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSC 247
C +C P EE +M+FCD C+ H C G+ +P G W+C C
Sbjct: 436 CIICGQPHHEE--EMMFCDMCDRGYHTFCVGLGAIPSGRWICDCC 478
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 45.1 bits (105), Expect = 3e-04
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 11/95 (11%)
Query: 194 GIEYDEDVICDVCRSPDSEEGNDMVFCD-KCNVCVHQACYGILKVPEGSWLCRSCVLGIY 252
G+ ++ +C +C P S ++ C+ C H AC G+ + PEG + C C GI+
Sbjct: 661 GVTAKKEYVCQLCEKPGS-----LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIH 715
Query: 253 PQCVLCPKKGGALK---TTKTGTKWAHVSCALWIP 284
C +C + +K T+ G K+ H +C P
Sbjct: 716 -SCFVCKESKTDVKRCVVTQCG-KFYHEACVKKYP 748
Score = 37.4 bits (85), Expect = 0.057
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 6/48 (12%)
Query: 203 CDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLG 250
C VC +G ++ C+ C H C I ++P+GSW C C G
Sbjct: 834 CFVC-----SKGGSLLCCESCPAAFHPDCLNI-EMPDGSWFCNDCRAG 875
Score = 33.5 bits (75), Expect = 0.82
Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 7/54 (12%)
Query: 213 EGNDMVFCDK--CNVCVHQACYGILKVPEGSWLC--RSCVLGIYPQ---CVLCP 259
+G +V CD+ C H +C G+ K P G W C C + P C LCP
Sbjct: 1247 DGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCP 1300
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 45.1 bits (105), Expect = 3e-04
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 11/95 (11%)
Query: 194 GIEYDEDVICDVCRSPDSEEGNDMVFCD-KCNVCVHQACYGILKVPEGSWLCRSCVLGIY 252
G+ ++ +C +C P S ++ C+ C H AC G+ + PEG + C C GI+
Sbjct: 661 GVTAKKEYVCQLCEKPGS-----LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIH 715
Query: 253 PQCVLCPKKGGALK---TTKTGTKWAHVSCALWIP 284
C +C + +K T+ G K+ H +C P
Sbjct: 716 -SCFVCKESKTDVKRCVVTQCG-KFYHEACVKKYP 748
Score = 37.4 bits (85), Expect = 0.057
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 6/48 (12%)
Query: 203 CDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLG 250
C VC +G ++ C+ C H C I ++P+GSW C C G
Sbjct: 834 CFVC-----SKGGSLLCCESCPAAFHPDCLNI-EMPDGSWFCNDCRAG 875
Score = 33.5 bits (75), Expect = 0.82
Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 7/54 (12%)
Query: 213 EGNDMVFCDK--CNVCVHQACYGILKVPEGSWLC--RSCVLGIYPQ---CVLCP 259
+G +V CD+ C H +C G+ K P G W C C + P C LCP
Sbjct: 1247 DGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCP 1300
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 45.1 bits (105), Expect = 3e-04
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 11/95 (11%)
Query: 194 GIEYDEDVICDVCRSPDSEEGNDMVFCD-KCNVCVHQACYGILKVPEGSWLCRSCVLGIY 252
G+ ++ +C +C P S ++ C+ C H AC G+ + PEG + C C GI+
Sbjct: 661 GVTAKKEYVCQLCEKPGS-----LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIH 715
Query: 253 PQCVLCPKKGGALK---TTKTGTKWAHVSCALWIP 284
C +C + +K T+ G K+ H +C P
Sbjct: 716 -SCFVCKESKTDVKRCVVTQCG-KFYHEACVKKYP 748
Score = 37.4 bits (85), Expect = 0.057
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 6/48 (12%)
Query: 203 CDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLG 250
C VC +G ++ C+ C H C I ++P+GSW C C G
Sbjct: 834 CFVC-----SKGGSLLCCESCPAAFHPDCLNI-EMPDGSWFCNDCRAG 875
Score = 33.5 bits (75), Expect = 0.82
Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 7/54 (12%)
Query: 213 EGNDMVFCDK--CNVCVHQACYGILKVPEGSWLC--RSCVLGIYPQ---CVLCP 259
+G +V CD+ C H +C G+ K P G W C C + P C LCP
Sbjct: 1247 DGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCP 1300
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,595,080
Number of Sequences: 37866
Number of extensions: 1762031
Number of successful extensions: 6790
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 6384
Number of HSP's gapped (non-prelim): 436
length of query: 823
length of database: 18,247,518
effective HSP length: 111
effective length of query: 712
effective length of database: 14,044,392
effective search space: 9999607104
effective search space used: 9999607104
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.