BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo sapiens] (142 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 279 5e-76 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 79 2e-15 gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 71 3e-13 gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 71 3e-13 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 70 6e-13 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 70 6e-13 gi|17975763 myelin transcription factor 1 [Homo sapiens] 69 2e-12 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 68 3e-12 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 67 5e-12 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 64 4e-11 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 64 4e-11 gi|58761548 tau tubulin kinase 1 [Homo sapiens] 63 7e-11 gi|21735569 claspin [Homo sapiens] 63 9e-11 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 62 1e-10 gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 62 2e-10 gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 62 2e-10 gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 61 3e-10 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 61 3e-10 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 61 3e-10 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 61 4e-10 gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 61 4e-10 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 60 5e-10 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 60 5e-10 gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 60 6e-10 gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 60 6e-10 gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 60 6e-10 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 60 6e-10 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 60 8e-10 gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 60 8e-10 gi|221219020 NYD-SP11 protein [Homo sapiens] 59 1e-09 >gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo sapiens] Length = 142 Score = 279 bits (714), Expect = 5e-76 Identities = 142/142 (100%), Positives = 142/142 (100%) Query: 1 MTAYGHSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGT 60 MTAYGHSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGT Sbjct: 1 MTAYGHSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGT 60 Query: 61 SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE Sbjct: 61 SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 Query: 121 VSFSLATRERETETEEKRLISP 142 VSFSLATRERETETEEKRLISP Sbjct: 121 VSFSLATRERETETEEKRLISP 142 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 78.6 bits (192), Expect = 2e-15 Identities = 37/76 (48%), Positives = 56/76 (73%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 RK + +++K +E ++R+EK EEK+R+ KR++K+EE+E EEEEEEEEEE+EEEE+EE Sbjct: 37 RKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRR 96 Query: 123 FSLATRERETETEEKR 138 + R E EE++ Sbjct: 97 RKKKKKRRRKEEEEEK 112 Score = 73.9 bits (180), Expect = 4e-14 Identities = 37/81 (45%), Positives = 56/81 (69%), Gaps = 5/81 (6%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 RK +R+E++++++ + EKR+E++ E KR+ K ++K+EEEE EEEEEEEEEE+EEEE Sbjct: 33 RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92 Query: 123 -----FSLATRERETETEEKR 138 R R+ E EEK+ Sbjct: 93 EGRRRKKKKKRRRKEEEEEKK 113 Score = 69.7 bits (169), Expect = 8e-13 Identities = 34/76 (44%), Positives = 53/76 (69%), Gaps = 1/76 (1%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 +K + +E ++R+EK EEK+R+ KR++ K+ E+E E+EEEEEEEE+EEEE+EE + Sbjct: 42 KKKKTKETEKRKEKEEEEKKRKRKRKK-KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100 Query: 123 FSLATRERETETEEKR 138 +E E E ++KR Sbjct: 101 KKRRRKEEEEEKKKKR 116 Score = 68.2 bits (165), Expect = 2e-12 Identities = 36/90 (40%), Positives = 55/90 (61%), Gaps = 11/90 (12%) Query: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEE-----------EEEEE 108 T + + +E +R+EKR+E+++ +EK+++ K EK +EKEEEE EEEE Sbjct: 16 TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEER 75 Query: 109 EEEEEEEEEEEEVSFSLATRERETETEEKR 138 EEEEEEEEEE+E R R+ + + +R Sbjct: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105 Score = 55.5 bits (132), Expect = 1e-08 Identities = 27/74 (36%), Positives = 47/74 (63%), Gaps = 1/74 (1%) Query: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 T RK + EEK+R+ KR++ K+ EE+R E + E+EE++EEE+EE +++++ +E Sbjct: 49 TEKRKEKEEEEKKRKRKRKK-KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 Query: 120 EVSFSLATRERETE 133 E R R+T+ Sbjct: 108 EEEEKKKKRRRKTK 121 Score = 52.4 bits (124), Expect = 1e-07 Identities = 19/57 (33%), Positives = 42/57 (73%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 +K + EE+ EE+ EE++ EE++ EG+RR+K++++ +EEEEE++++ + +++ Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 Score = 52.0 bits (123), Expect = 2e-07 Identities = 21/58 (36%), Positives = 41/58 (70%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 RK ++ EE+R EE+ EE+ +EE+ +E RR K+++K +EEEEE++++ + +++ Sbjct: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 Score = 47.0 bits (110), Expect = 5e-06 Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 1/70 (1%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KEE R + +R EE+ EE+ +EE+ +EE RR K+++K KEEEEE++ Sbjct: 55 KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR-KKKKKRRRKEEEEEKK 113 Query: 107 EEEEEEEEEE 116 ++ + +++ Sbjct: 114 KKRRRKTKKK 123 Score = 42.0 bits (97), Expect = 2e-04 Identities = 17/75 (22%), Positives = 41/75 (54%) Query: 40 TNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEK 99 T +EE + + + EE+ EE++ EE++ E +RR+ K++ + +E+ Sbjct: 49 TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108 Query: 100 EEEEEEEEEEEEEEE 114 EEE++++ + +++ Sbjct: 109 EEEKKKKRRRKTKKK 123 >gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] Length = 1113 Score = 71.2 bits (173), Expect = 3e-13 Identities = 42/101 (41%), Positives = 57/101 (56%), Gaps = 16/101 (15%) Query: 50 PPTLRHS---------MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKE 100 PP L HS M+G SA + Q EE RRE +R E+ RE +R + REKE E+E Sbjct: 203 PPELSHSSLAALHSERMSGLSAERLQMDEELRRERER--EREREREREADREREKERERE 260 Query: 101 EEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141 E+E E+E+E E E+E E E+ R+RE EK L++ Sbjct: 261 REKEREQEKEREREKERERELE-----RQREQRAREKELLA 296 Score = 46.6 bits (109), Expect = 7e-06 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93 E ++GL+ + EE R + RE ++ E+ RE++R +EK RE R Sbjct: 217 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---R 273 Query: 94 EKEEEKEEEEEEEEEEEEEE 113 EKE E+E E + E+ E+E Sbjct: 274 EKERERELERQREQRAREKE 293 Score = 32.0 bits (71), Expect = 0.18 Identities = 13/30 (43%), Positives = 22/30 (73%) Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121 R+ ++ + + EEEEEE++E+ E+EEEV Sbjct: 985 RKGPPTQELDRDSEEEEEEDDEDGEDEEEV 1014 Score = 31.6 bits (70), Expect = 0.23 Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 87 RREGKRREKEEEKEEEEEEEEEEEEEEEE 115 R+ +E + + EEEEEE++E+ E+EEE Sbjct: 985 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1013 Score = 31.6 bits (70), Expect = 0.23 Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 88 REGKRREKEEEKEEEEEEEEEEEEEEEEE 116 R+G ++ + EEEEEE++E+ E+EEE Sbjct: 985 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1013 Score = 30.8 bits (68), Expect = 0.39 Identities = 16/59 (27%), Positives = 32/59 (54%) Query: 82 RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140 R+ +E R +EEE+E++E+ E+EEE + + + E F E + E++++ Sbjct: 985 RKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVL 1043 Score = 28.9 bits (63), Expect = 1.5 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 3/95 (3%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 ++EPPT R + EE+ +E +E+ +++ +G E +E EE+ Sbjct: 978 QQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQN 1037 Query: 107 EEEEEEEEE---EEEEEVSFSLATRERETETEEKR 138 E + + + E S SL + E R Sbjct: 1038 LERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELR 1072 Score = 26.2 bits (56), Expect = 9.7 Identities = 11/43 (25%), Positives = 21/43 (48%) Query: 78 REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 + R + G++ K +E + + EEEEEE++E+ Sbjct: 965 QSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDED 1007 >gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] Length = 1217 Score = 71.2 bits (173), Expect = 3e-13 Identities = 42/101 (41%), Positives = 57/101 (56%), Gaps = 16/101 (15%) Query: 50 PPTLRHS---------MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKE 100 PP L HS M+G SA + Q EE RRE +R E+ RE +R + REKE E+E Sbjct: 307 PPELSHSSLAALHSERMSGLSAERLQMDEELRRERER--EREREREREADREREKERERE 364 Query: 101 EEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141 E+E E+E+E E E+E E E+ R+RE EK L++ Sbjct: 365 REKEREQEKEREREKERERELE-----RQREQRAREKELLA 400 Score = 46.6 bits (109), Expect = 7e-06 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93 E ++GL+ + EE R + RE ++ E+ RE++R +EK RE R Sbjct: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---R 377 Query: 94 EKEEEKEEEEEEEEEEEEEE 113 EKE E+E E + E+ E+E Sbjct: 378 EKERERELERQREQRAREKE 397 Score = 32.0 bits (71), Expect = 0.18 Identities = 13/30 (43%), Positives = 22/30 (73%) Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121 R+ ++ + + EEEEEE++E+ E+EEEV Sbjct: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEEV 1118 Score = 31.6 bits (70), Expect = 0.23 Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 87 RREGKRREKEEEKEEEEEEEEEEEEEEEE 115 R+ +E + + EEEEEE++E+ E+EEE Sbjct: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1117 Score = 31.6 bits (70), Expect = 0.23 Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 88 REGKRREKEEEKEEEEEEEEEEEEEEEEE 116 R+G ++ + EEEEEE++E+ E+EEE Sbjct: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1117 Score = 30.8 bits (68), Expect = 0.39 Identities = 16/59 (27%), Positives = 32/59 (54%) Query: 82 RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140 R+ +E R +EEE+E++E+ E+EEE + + + E F E + E++++ Sbjct: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVL 1147 Score = 28.9 bits (63), Expect = 1.5 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 3/95 (3%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 ++EPPT R + EE+ +E +E+ +++ +G E +E EE+ Sbjct: 1082 QQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQN 1141 Query: 107 EEEEEEEEE---EEEEEVSFSLATRERETETEEKR 138 E + + + E S SL + E R Sbjct: 1142 LERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELR 1176 Score = 26.2 bits (56), Expect = 9.7 Identities = 11/43 (25%), Positives = 21/43 (48%) Query: 78 REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 + R + G++ K +E + + EEEEEE++E+ Sbjct: 1069 QSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDED 1111 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 70.1 bits (170), Expect = 6e-13 Identities = 36/93 (38%), Positives = 60/93 (64%), Gaps = 1/93 (1%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 K+E R A + R +++RE++RRE++RRE++RRE++RRE +RRE+E + E+E Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 726 Query: 107 EEEE-EEEEEEEEEEVSFSLATRERETETEEKR 138 E+E + E E +E E + L + + E EEK+ Sbjct: 727 EQERLQAERELQEREKALRLQKEQLQRELEEKK 759 Score = 58.9 bits (141), Expect = 1e-09 Identities = 33/87 (37%), Positives = 57/87 (65%), Gaps = 12/87 (13%) Query: 63 RKSQRREEKRREEKRREEKRRE--------EKRREGKRREKEEEKEEEEE----EEEEEE 110 R+ +RRE++RRE++RRE++RRE E+RRE +R + E E +E E+ ++E+ + Sbjct: 693 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 752 Query: 111 EEEEEEEEEEVSFSLATRERETETEEK 137 E EE++++E LA R+ + E E+K Sbjct: 753 RELEEKKKKEEQQRLAERQLQEEQEKK 779 Score = 54.3 bits (129), Expect = 3e-08 Identities = 27/94 (28%), Positives = 50/94 (53%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE 105 +++E RH ++ ++ ++ E +R ++RE++RRE +RRE+E ++E E+ Sbjct: 651 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 710 Query: 106 EEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 E E+E + E+E ERE + EK L Sbjct: 711 ERREQERQLAEQERRREQERLQAERELQEREKAL 744 Score = 52.0 bits (123), Expect = 2e-07 Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 +EE LR R+ Q +K++EE++ ++ E +R ++RE+E ++E E+E Sbjct: 642 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 701 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETE 135 E+E E+E E+ LA +ER E E Sbjct: 702 RREQERREQERREQ-ERQLAEQERRREQE 729 Score = 46.2 bits (108), Expect = 9e-06 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 13/119 (10%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93 + A + T KEE + +A+K + E +R++E+ R ++ E +R Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 660 Query: 94 EKEEEKEEEEEEE-------------EEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 ++ +K++EEE+E + E+E E+E E+ RE+E +E++L Sbjct: 661 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 719 Score = 43.1 bits (100), Expect = 8e-05 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 14/90 (15%) Query: 63 RKSQRREEKRR--EEK-----RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE-- 113 R Q +EEK++ E+K + EK +EE+ E K ++K K+ EE E ++EEE Sbjct: 587 RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 646 Query: 114 -----EEEEEEEVSFSLATRERETETEEKR 138 ++EEEE L +++E E E R Sbjct: 647 RLRWLQQEEEERRHQELLQKKKEEEQERLR 676 Score = 42.4 bits (98), Expect = 1e-04 Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 40/103 (38%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKR------------------------------ 92 R+ +RRE++RRE++RRE++RRE++RRE +R Sbjct: 688 REQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 747 Query: 93 ----------REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125 ++K+EE++ E + +EE+E++ +E S +L Sbjct: 748 KEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 790 Score = 42.0 bits (97), Expect = 2e-04 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 14/129 (10%) Query: 23 LSTFPYPHSKRENLAGLTNSTSSV-----KEEPPTLRHSMAGTSARKSQRREEKRREEKR 77 L TF + + + L T++ SV K P ++ QR E RR+E+ Sbjct: 492 LRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEA 551 Query: 78 REEKRREEKRREGKRREKEEEKEEEEE------EEEEEEEEEEEEEEEEVSFSLATRERE 131 E+ R +K E KRR EE K + EE + E E+ +EE+++++ A + + Sbjct: 552 --EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 609 Query: 132 TE-TEEKRL 139 TE +E+RL Sbjct: 610 TEKAKEERL 618 Score = 40.8 bits (94), Expect = 4e-04 Identities = 20/60 (33%), Positives = 41/60 (68%), Gaps = 2/60 (3%) Query: 62 ARKSQRREEKRREEKRREEKRREEKR--REGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 A + +RRE++R + +R ++R + R +E +RE EE+K++EE++ E + +EE+E++ Sbjct: 720 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 779 Score = 39.7 bits (91), Expect = 8e-04 Identities = 23/92 (25%), Positives = 46/92 (50%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KEE LR R+ + +REE+ R+ + E+ + K +K++ +++ + + Sbjct: 548 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 607 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+ E+ +EE EE + A ++ E E +R Sbjct: 608 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 639 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 70.1 bits (170), Expect = 6e-13 Identities = 36/93 (38%), Positives = 60/93 (64%), Gaps = 1/93 (1%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 K+E R A + R +++RE++RRE++RRE++RRE++RRE +RRE+E + E+E Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 722 Query: 107 EEEE-EEEEEEEEEEVSFSLATRERETETEEKR 138 E+E + E E +E E + L + + E EEK+ Sbjct: 723 EQERLQAERELQEREKALRLQKEQLQRELEEKK 755 Score = 58.9 bits (141), Expect = 1e-09 Identities = 33/87 (37%), Positives = 57/87 (65%), Gaps = 12/87 (13%) Query: 63 RKSQRREEKRREEKRREEKRRE--------EKRREGKRREKEEEKEEEEE----EEEEEE 110 R+ +RRE++RRE++RRE++RRE E+RRE +R + E E +E E+ ++E+ + Sbjct: 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 748 Query: 111 EEEEEEEEEEVSFSLATRERETETEEK 137 E EE++++E LA R+ + E E+K Sbjct: 749 RELEEKKKKEEQQRLAERQLQEEQEKK 775 Score = 54.3 bits (129), Expect = 3e-08 Identities = 27/94 (28%), Positives = 50/94 (53%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE 105 +++E RH ++ ++ ++ E +R ++RE++RRE +RRE+E ++E E+ Sbjct: 647 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 706 Query: 106 EEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 E E+E + E+E ERE + EK L Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREKAL 740 Score = 52.0 bits (123), Expect = 2e-07 Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 +EE LR R+ Q +K++EE++ ++ E +R ++RE+E ++E E+E Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETE 135 E+E E+E E+ LA +ER E E Sbjct: 698 RREQERREQERREQ-ERQLAEQERRREQE 725 Score = 46.2 bits (108), Expect = 9e-06 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 13/119 (10%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93 + A + T KEE + +A+K + E +R++E+ R ++ E +R Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656 Query: 94 EKEEEKEEEEEEE-------------EEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 ++ +K++EEE+E + E+E E+E E+ RE+E +E++L Sbjct: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715 Score = 43.1 bits (100), Expect = 8e-05 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 14/90 (15%) Query: 63 RKSQRREEKRR--EEK-----RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE-- 113 R Q +EEK++ E+K + EK +EE+ E K ++K K+ EE E ++EEE Sbjct: 583 RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 642 Query: 114 -----EEEEEEEVSFSLATRERETETEEKR 138 ++EEEE L +++E E E R Sbjct: 643 RLRWLQQEEEERRHQELLQKKKEEEQERLR 672 Score = 42.4 bits (98), Expect = 1e-04 Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 40/103 (38%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKR------------------------------ 92 R+ +RRE++RRE++RRE++RRE++RRE +R Sbjct: 684 REQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 743 Query: 93 ----------REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125 ++K+EE++ E + +EE+E++ +E S +L Sbjct: 744 KEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786 Score = 40.8 bits (94), Expect = 4e-04 Identities = 20/60 (33%), Positives = 41/60 (68%), Gaps = 2/60 (3%) Query: 62 ARKSQRREEKRREEKRREEKRREEKR--REGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 A + +RRE++R + +R ++R + R +E +RE EE+K++EE++ E + +EE+E++ Sbjct: 716 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775 Score = 40.0 bits (92), Expect = 7e-04 Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 9/84 (10%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE------EEEEEEEEEEEE 116 ++ QR E RR+E+ E+ R +K E KRR EE K + EE + E E+ +EE Sbjct: 533 KERQRLENLRRKEEA--EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590 Query: 117 EEEEVSFSLATRERETE-TEEKRL 139 +++++ A + +TE +E+RL Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERL 614 Score = 39.7 bits (91), Expect = 8e-04 Identities = 23/92 (25%), Positives = 46/92 (50%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KEE LR R+ + +REE+ R+ + E+ + K +K++ +++ + + Sbjct: 544 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+ E+ +EE EE + A ++ E E +R Sbjct: 604 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 635 Score = 35.4 bits (80), Expect = 0.016 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 8/88 (9%) Query: 57 MAGTSARKS------QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEE 110 M TSA +S +R R + K +E +R E RR K ++ +++ EE++ Sbjct: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR--KEEAEQLRRQKVEEDKRRRL 563 Query: 111 EEEEEEEEEEVSFSLATRERETETEEKR 138 EE + + EE + L RER + +E++ Sbjct: 564 EEVKLKREERLRKVLQARERVEQMKEEK 591 Score = 34.3 bits (77), Expect = 0.036 Identities = 19/77 (24%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Query: 63 RKSQRREEKRREEKRREEKRR--EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 R+ + E+ RR++ +++RR E K + +R K + E E+ +EE++++ E++ + Sbjct: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 601 Query: 121 VSFSLATRERETETEEK 137 + + E EEK Sbjct: 602 IDEKTEKAKEERLAEEK 618 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 68.6 bits (166), Expect = 2e-12 Identities = 36/88 (40%), Positives = 51/88 (57%) Query: 51 PTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEE 110 P A + K + E++ EE+ EE+ E + E+EEE+EEEEEEEEEEE Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296 Query: 111 EEEEEEEEEEVSFSLATRERETETEEKR 138 EEEEEEEEEE + + +E + T ++ Sbjct: 297 EEEEEEEEEEAAPDVIFQEDTSHTSAQK 324 Score = 67.8 bits (164), Expect = 3e-12 Identities = 33/70 (47%), Positives = 47/70 (67%) Query: 50 PPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE 109 P +L + + S+++ + +E+ EE+ EE+ E + E+EEE+EEEEEEEEEE Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296 Query: 110 EEEEEEEEEE 119 EEEEEEEEEE Sbjct: 297 EEEEEEEEEE 306 Score = 62.4 bits (150), Expect = 1e-10 Identities = 34/82 (41%), Positives = 48/82 (58%) Query: 61 SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 + +SQ + E+ EE +++ + ++EEE+EEEEEEE+EEEEEEEEEEEEE Sbjct: 228 TTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 287 Query: 121 VSFSLATRERETETEEKRLISP 142 E E E EE+ +P Sbjct: 288 EEEEEEEEEEEEEEEEEEEAAP 309 Score = 58.5 bits (140), Expect = 2e-09 Identities = 33/89 (37%), Positives = 46/89 (51%) Query: 49 EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108 +P + T+ R + + E +++ + E+EEE+EEEEEE+EE Sbjct: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEE 276 Query: 109 EEEEEEEEEEEEVSFSLATRERETETEEK 137 EEEEEEEEEEEE E E E EE+ Sbjct: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305 Score = 57.0 bits (136), Expect = 5e-09 Identities = 29/73 (39%), Positives = 43/73 (58%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 + + EE+ EE+ EE+ EE+ E + E+EEE+EEEEEEEEEEE + +E+ S Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319 Query: 124 SLATRERETETEE 136 + A + E E Sbjct: 320 TSAQKAPELRGPE 332 Score = 49.7 bits (117), Expect = 8e-07 Identities = 24/64 (37%), Positives = 36/64 (56%) Query: 45 SVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE 104 + EE + ++ + + EE+ EE EE+ EE+ E + E+EEE+EEEEE Sbjct: 243 AASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302 Query: 105 EEEE 108 EEEE Sbjct: 303 EEEE 306 Score = 49.7 bits (117), Expect = 8e-07 Identities = 25/71 (35%), Positives = 39/71 (54%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 + + EE+ E++ EE+ EE+ E + E+EEE+EEEEEEEE + +E+ S Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSA 322 Query: 124 SLATRERETET 134 A R E+ Sbjct: 323 QKAPELRGPES 333 Score = 40.0 bits (92), Expect = 7e-04 Identities = 22/77 (28%), Positives = 37/77 (48%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 + + EE EE+ EE+ EE+ E + E+EEE+EEEE + +E+ + + Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAP 326 Query: 124 SLATRERETETEEKRLI 140 L E + E +I Sbjct: 327 ELRGPESPSPKPEYSVI 343 Score = 38.1 bits (87), Expect = 0.002 Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 7/110 (6%) Query: 17 ENDRILLSTFPYPHSKRENLAGLTNSTSS---VKEEPPTLRHSMAGTSARKSQRREEKRR 73 EN + LS + H KREN ++S SS VK + RHS TSA S + Sbjct: 665 ENGTLDLSM--HKHRKRENAFPSSSSCSSSPGVKSPDASQRHS--STSAPSSSMTSPQSS 720 Query: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 + R++E R + R +EE +E E E +++E E +F Sbjct: 721 QASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENF 770 Score = 28.1 bits (61), Expect = 2.6 Identities = 18/85 (21%), Positives = 39/85 (45%) Query: 53 LRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112 L+ + G ++ + ++ + E+ + E+ ++ + E+ EE +++ Sbjct: 198 LQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSH 257 Query: 113 EEEEEEEEVSFSLATRERETETEEK 137 EEE+EEEE + E E EE+ Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEE 282 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 67.8 bits (164), Expect = 3e-12 Identities = 36/106 (33%), Positives = 59/106 (55%), Gaps = 11/106 (10%) Query: 44 SSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEE 103 S ++E + G R+S+R++E+R EKR+ E+ +E KR GK+ +K E K+EE Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95 Query: 104 E-----------EEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E E EE+E+ +++E++E S +ERE + E KR Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141 Score = 66.2 bits (160), Expect = 8e-12 Identities = 32/107 (29%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 ++EN G KE+ R S G ++ +R+EE++REE++ E+++EE+ +E + Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEG---KERERKEERKREERKERERKKEEREKERE 159 Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 R+E+++ + ++ E+EEE +E+E +E ++ + R++E E +E+R Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206 Score = 61.2 bits (147), Expect = 3e-10 Identities = 37/109 (33%), Positives = 57/109 (52%), Gaps = 17/109 (15%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREE------------KRREEKRR-----E 89 K E R G +K +R++E+R +KRR E K++E+K R E Sbjct: 70 KREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE 129 Query: 90 GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 GK RE++EE++ EE +E E ++EE E+E E R++ E EE+R Sbjct: 130 GKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178 Score = 58.5 bits (140), Expect = 2e-09 Identities = 25/71 (35%), Positives = 49/71 (69%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 +K +R++ +EE+R+E++R+E K+RE R+E+++E+E +E E ++E +++EE ++E Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQ 223 Query: 123 FSLATRERETE 133 T RE E Sbjct: 224 KDRQTNWREKE 234 Score = 56.2 bits (134), Expect = 9e-09 Identities = 25/78 (32%), Positives = 52/78 (66%), Gaps = 3/78 (3%) Query: 63 RKSQRREEKRREEKR---REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 ++ +R+E K+RE K+ +EE+R+E++R+E K+RE+ ++ ++E E +E E ++E +++ Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215 Query: 120 EVSFSLATRERETETEEK 137 E ++R+T EK Sbjct: 216 EERKKERQKDRQTNWREK 233 Score = 55.1 bits (131), Expect = 2e-08 Identities = 23/72 (31%), Positives = 50/72 (69%), Gaps = 1/72 (1%) Query: 68 REEKRREEKRREEKRREEKRREGKR-REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126 +EE+R+E++R+E K+RE R+E K+ RE++E +E ++E +++EE ++E +++ + ++ Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233 Query: 127 TRERETETEEKR 138 R + E K+ Sbjct: 234 ERGKRERKERKK 245 Score = 54.7 bits (130), Expect = 3e-08 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 2/109 (1%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKR--REEKRREEKRREEKRRE 89 K + G T+ +E + RK + RE++R +E K+RE K+ EK E Sbjct: 118 KEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEE 177 Query: 90 GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 K +E++E K+ E +E ++E E +E E ER+ E ++ R Sbjct: 178 RKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226 Score = 53.9 bits (128), Expect = 4e-08 Identities = 28/87 (32%), Positives = 53/87 (60%), Gaps = 11/87 (12%) Query: 63 RKSQRREEKRREEKRREEKRREEKR------REGKRREKEEEKEEEEEEE-----EEEEE 111 RK +RRE++ +E + +E+++++EK+ +EGK RE++EE++ EE +E EE E+ Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156 Query: 112 EEEEEEEEEVSFSLATRERETETEEKR 138 E E +E ++ + E E++R Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKER 183 Score = 53.9 bits (128), Expect = 4e-08 Identities = 21/68 (30%), Positives = 46/68 (67%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 K + R+EK R+E+++ E+ R+E+++E +R+E+ E K+E +++EE ++E +++ + Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233 Query: 124 SLATRERE 131 RER+ Sbjct: 234 ERGKRERK 241 Score = 52.8 bits (125), Expect = 1e-07 Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 RK +E+ R+EK R+E+++ E+ R K R+KE E++E E ++E +++EE ++E + Sbjct: 168 RKQVGEKEEERKEKERKERKKRERNR--KERKKERERKERRERKKERKKKEERKKERQKD 225 Query: 123 FSLATRERETETEEKR 138 RE+E E++ Sbjct: 226 RQTNWREKERGKRERK 241 Score = 50.8 bits (120), Expect = 4e-07 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 4/78 (5%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE---EEEEEEEEEEE 120 +S+ RE +R E R+E K+ E R+ +RRE+E+ K E E+E + E +E++ E ++EE Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94 Query: 121 VSFSLATRERET-ETEEK 137 RE+E E EEK Sbjct: 95 RERKKRRREKENKEGEEK 112 Score = 48.9 bits (115), Expect = 1e-06 Identities = 20/69 (28%), Positives = 48/69 (69%), Gaps = 2/69 (2%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 RK + R+E+++ E+ R+E+++E +R+E RRE+++E++++EE ++E +++ + E+ Sbjct: 178 RKEKERKERKKRERNRKERKKERERKE--RRERKKERKKKEERKKERQKDRQTNWREKER 235 Query: 123 FSLATRERE 131 +ER+ Sbjct: 236 GKRERKERK 244 Score = 44.3 bits (103), Expect = 3e-05 Identities = 15/58 (25%), Positives = 40/58 (68%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 ++ + R+E+++E +R+E + R+++R++ + R+KE +K+ + E+E + E +E ++ Sbjct: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245 Score = 40.0 bits (92), Expect = 7e-04 Identities = 17/67 (25%), Positives = 37/67 (55%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KE+ R + + RE K R E+++E K++EE+++E ++ + +E+E + Sbjct: 179 KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238 Query: 107 EEEEEEE 113 E +E ++ Sbjct: 239 ERKERKK 245 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 67.0 bits (162), Expect = 5e-12 Identities = 39/90 (43%), Positives = 48/90 (53%), Gaps = 3/90 (3%) Query: 50 PPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE 109 PP L + + S EE+ EE+ EE+ EE+ + E EEE EEEEEEEEE Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930 Query: 110 EEEEEEEEEEEVSFSLATRERETETEEKRL 139 EEE EEEE E+ E E E EE+ L Sbjct: 931 FEEEFEEEEGELE---EEEEEEDEEEEEEL 957 Score = 60.8 bits (146), Expect = 4e-10 Identities = 41/112 (36%), Positives = 56/112 (50%), Gaps = 6/112 (5%) Query: 25 TFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRRE 84 T P P E G +++E+ + + + + + EE+ EE+ EE E Sbjct: 854 TLPPPQLVPEGTPG-GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912 Query: 85 EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEE 136 E+ E + E+EEE+EEE EEE EEEE E EEEEEE E E E EE Sbjct: 913 EEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE-----EDEEEEEELEE 959 Score = 55.8 bits (133), Expect = 1e-08 Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 2/104 (1%) Query: 29 PHSKRENLAGLT-NSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKR 87 P + E+L + NS+ +EE + EE+ EE+ EE+ EE+ Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930 Query: 88 REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERE 131 E + E+E E EEEEEE E+EEEEEE EE E++ F A E E Sbjct: 931 FEEEFEEEEGELEEEEEE-EDEEEEEELEEVEDLEFGTAGGEVE 973 Score = 37.7 bits (86), Expect = 0.003 Identities = 22/52 (42%), Positives = 29/52 (55%) Query: 69 EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 EE+ EE+ EE EE E + E++EE+EEE EE E+ E E EE Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974 Score = 32.0 bits (71), Expect = 0.18 Identities = 19/53 (35%), Positives = 28/53 (52%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEE 116 + + EE+ EE+ EE+ E+ E + E+EEE EE E+ E E EE Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974 Score = 29.6 bits (65), Expect = 0.88 Identities = 18/52 (34%), Positives = 27/52 (51%) Query: 66 QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117 + EE+ E+ EE+ E + E + E+EEE+ EE E+ E E EE Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974 Score = 27.7 bits (60), Expect = 3.3 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 3/113 (2%) Query: 16 PENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREE 75 PE + LL P ++ E A T T + + P G S +E EE Sbjct: 999 PEPEPGLLLEVEEPGTEEERGAD-TAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEE 1057 Query: 76 KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE--EEEEEEEVSFSLA 126 EE+ +G + + + EEE E E E E +E+E+++ + LA Sbjct: 1058 PSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLA 1110 Score = 26.2 bits (56), Expect = 9.7 Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 7/62 (11%) Query: 85 EKRREGKRREKEEEKEEEEEEEE-------EEEEEEEEEEEEEVSFSLATRERETETEEK 137 E REG+ +E EEE EEE E+ ++ + + A E ETETE + Sbjct: 1036 EVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAE 1095 Query: 138 RL 139 L Sbjct: 1096 AL 1097 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 63.9 bits (154), Expect = 4e-11 Identities = 34/67 (50%), Positives = 48/67 (71%), Gaps = 3/67 (4%) Query: 61 SARKSQRREEKR---REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117 SA+K++ E +R +++KRR K +E+ E K +EEE+E+EEEEEEEEEEEEEEE+ Sbjct: 1368 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1427 Query: 118 EEEVSFS 124 E + S S Sbjct: 1428 ENDDSKS 1434 Score = 61.2 bits (147), Expect = 3e-10 Identities = 29/61 (47%), Positives = 41/61 (67%) Query: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 T + K EE +R K+++++RR + + + K +EEEEE+EEEEEEEEEEEEEE Sbjct: 1366 TRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1425 Query: 120 E 120 E Sbjct: 1426 E 1426 Score = 54.3 bits (129), Expect = 3e-08 Identities = 27/85 (31%), Positives = 49/85 (57%), Gaps = 2/85 (2%) Query: 37 AGLTNSTSSVKEEPPTLRHSMAGTSARKSQR--REEKRREEKRREEKRREEKRREGKRRE 94 +G++ S ++E S ++QR +++K+R + +E E + + E Sbjct: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1408 Query: 95 KEEEKEEEEEEEEEEEEEEEEEEEE 119 +E+E+EEEEEEEEEEEEE+E ++ + Sbjct: 1409 EEKEEEEEEEEEEEEEEEDENDDSK 1433 Score = 52.4 bits (124), Expect = 1e-07 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 16/91 (17%) Query: 58 AGTSARKSQRREEKRR----------EEKRREEKRREEKRREGKRREKEEEKEEEEEEEE 107 +G S S+ +E+R EE +R K+++++RR + + E + EEEE Sbjct: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1408 Query: 108 EEEEEEEEEEEEEVSFSLATRERETETEEKR 138 EE+EEEEEEEEEE E E E ++ + Sbjct: 1409 EEKEEEEEEEEEE------EEEEEDENDDSK 1433 Score = 50.1 bits (118), Expect = 6e-07 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 7/110 (6%) Query: 33 RENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKR 92 R ++ + S +E + S + R R +K E+ + ++++KRR K Sbjct: 1333 RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV 1392 Query: 93 REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLISP 142 +E + + EEEEEE+EEEEEEEEE E E E E SP Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEE-------EEEEEEDENDDSKSP 1435 Score = 48.1 bits (113), Expect = 2e-06 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 26/96 (27%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEE------- 115 +K +RR K +E+ E K E+ E K E+EEE+EEEEEEEE+E ++ + Sbjct: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKE-EEEEEEEEEEEEEEDENDDSKSPGKGRKK 1441 Query: 116 ------------------EEEEEVSFSLATRERETE 133 +EEEE +A RERE E Sbjct: 1442 IRKILKDDKLRTETQNALKEEEERRKRIAERERERE 1477 Score = 40.8 bits (94), Expect = 4e-04 Identities = 22/86 (25%), Positives = 42/86 (48%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE 105 V+E+ + S + + + EE+ EE+ EE ++ + GK R+K + ++++ Sbjct: 1392 VQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL 1451 Query: 106 EEEEEEEEEEEEEEEVSFSLATRERE 131 E + +EEEE + RERE Sbjct: 1452 RTETQNALKEEEERRKRIAERERERE 1477 Score = 33.5 bits (75), Expect = 0.061 Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 10/112 (8%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93 +N + + S + + P RH + K + + EEK+ + K +E + +R+ Sbjct: 1279 KNQVNSESDSDSEESKKPRYRHRLL---RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1335 Query: 94 EKEEEKEEEE-------EEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+ E+ + EE E E+E+ L +R + ++KR Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1387 Score = 32.3 bits (72), Expect = 0.14 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 8/92 (8%) Query: 53 LRHSMAGTSARKSQRREEKRREEKR-REEKRREEKRREGKRREKEEEKEEEEEEEEEEEE 111 LRH + + + ++ K +E K + RR+ + + + +E EE E E+E+ Sbjct: 1303 LRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1362 Query: 112 -------EEEEEEEEEVSFSLATRERETETEE 136 ++ E EE + S+ + R + +E Sbjct: 1363 RPRTRSAKKAELEENQRSYKQKKKRRRIKVQE 1394 Score = 30.0 bits (66), Expect = 0.67 Identities = 15/41 (36%), Positives = 23/41 (56%) Query: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108 +++K R E + K EE+R+ RE+E EK E E E+ Sbjct: 1447 KDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED 1487 Score = 29.6 bits (65), Expect = 0.88 Identities = 12/46 (26%), Positives = 25/46 (54%) Query: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 E+ +++ E K+R GK+ E+ EE + + E + + EE ++ Sbjct: 1250 EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1295 Score = 29.3 bits (64), Expect = 1.1 Identities = 19/98 (19%), Positives = 42/98 (42%), Gaps = 4/98 (4%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRR----EEKRREEKRREEKR 87 +R NL+ N+ + + + +K QR K++ +EK+R R KR Sbjct: 1098 ERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKR 1157 Query: 88 REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125 ++ E++++ E +E++ + V+ +L Sbjct: 1158 KQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENL 1195 Score = 29.3 bits (64), Expect = 1.1 Identities = 16/67 (23%), Positives = 30/67 (44%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 K EE + E+ +++ EGK+R ++ +E +EE + + E + + E S Sbjct: 1235 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1294 Query: 124 SLATRER 130 R R Sbjct: 1295 KPRYRHR 1301 Score = 28.1 bits (61), Expect = 2.6 Identities = 18/106 (16%), Positives = 44/106 (41%), Gaps = 4/106 (3%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAG----TSARKSQRREEKRREEKRREEKRREEKRRE 89 E+L + +V +E T H + T ARK ++ +++ + E + K+ + Sbjct: 373 EDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVD 432 Query: 90 GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135 + + EE+ + E ++ + +EE + A + + + Sbjct: 433 SEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMD 478 Score = 26.6 bits (57), Expect = 7.4 Identities = 23/108 (21%), Positives = 46/108 (42%), Gaps = 5/108 (4%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 KR L G ++ T ++SM S +R +R E R E+R +R K Sbjct: 1054 KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKR--LKRIELR--ERRNLSSKRNTK 1109 Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERET-ETEEKR 138 + + EE E+ +++++ ++ + + ++R + T KR Sbjct: 1110 EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKR 1157 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 63.9 bits (154), Expect = 4e-11 Identities = 34/67 (50%), Positives = 48/67 (71%), Gaps = 3/67 (4%) Query: 61 SARKSQRREEKR---REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117 SA+K++ E +R +++KRR K +E+ E K +EEE+E+EEEEEEEEEEEEEEE+ Sbjct: 1406 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1465 Query: 118 EEEVSFS 124 E + S S Sbjct: 1466 ENDDSKS 1472 Score = 61.2 bits (147), Expect = 3e-10 Identities = 29/61 (47%), Positives = 41/61 (67%) Query: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 T + K EE +R K+++++RR + + + K +EEEEE+EEEEEEEEEEEEEE Sbjct: 1404 TRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1463 Query: 120 E 120 E Sbjct: 1464 E 1464 Score = 54.3 bits (129), Expect = 3e-08 Identities = 27/85 (31%), Positives = 49/85 (57%), Gaps = 2/85 (2%) Query: 37 AGLTNSTSSVKEEPPTLRHSMAGTSARKSQR--REEKRREEKRREEKRREEKRREGKRRE 94 +G++ S ++E S ++QR +++K+R + +E E + + E Sbjct: 1387 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1446 Query: 95 KEEEKEEEEEEEEEEEEEEEEEEEE 119 +E+E+EEEEEEEEEEEEE+E ++ + Sbjct: 1447 EEKEEEEEEEEEEEEEEEDENDDSK 1471 Score = 52.4 bits (124), Expect = 1e-07 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 16/91 (17%) Query: 58 AGTSARKSQRREEKRR----------EEKRREEKRREEKRREGKRREKEEEKEEEEEEEE 107 +G S S+ +E+R EE +R K+++++RR + + E + EEEE Sbjct: 1387 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1446 Query: 108 EEEEEEEEEEEEEVSFSLATRERETETEEKR 138 EE+EEEEEEEEEE E E E ++ + Sbjct: 1447 EEKEEEEEEEEEE------EEEEEDENDDSK 1471 Score = 50.1 bits (118), Expect = 6e-07 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 7/110 (6%) Query: 33 RENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKR 92 R ++ + S +E + S + R R +K E+ + ++++KRR K Sbjct: 1371 RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV 1430 Query: 93 REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLISP 142 +E + + EEEEEE+EEEEEEEEE E E E E SP Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEE-------EEEEEEDENDDSKSP 1473 Score = 48.1 bits (113), Expect = 2e-06 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 26/96 (27%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEE------- 115 +K +RR K +E+ E K E+ E K E+EEE+EEEEEEEE+E ++ + Sbjct: 1421 QKKKRRRIKVQEDSSSENKSNSEEEEEEKE-EEEEEEEEEEEEEEDENDDSKSPGKGRKK 1479 Query: 116 ------------------EEEEEVSFSLATRERETE 133 +EEEE +A RERE E Sbjct: 1480 IRKILKDDKLRTETQNALKEEEERRKRIAERERERE 1515 Score = 40.8 bits (94), Expect = 4e-04 Identities = 22/86 (25%), Positives = 42/86 (48%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE 105 V+E+ + S + + + EE+ EE+ EE ++ + GK R+K + ++++ Sbjct: 1430 VQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL 1489 Query: 106 EEEEEEEEEEEEEEEVSFSLATRERE 131 E + +EEEE + RERE Sbjct: 1490 RTETQNALKEEEERRKRIAERERERE 1515 Score = 33.5 bits (75), Expect = 0.061 Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 10/112 (8%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93 +N + + S + + P RH + K + + EEK+ + K +E + +R+ Sbjct: 1317 KNQVNSESDSDSEESKKPRYRHRLL---RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1373 Query: 94 EKEEEKEEEE-------EEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+ E+ + EE E E+E+ L +R + ++KR Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1425 Score = 32.3 bits (72), Expect = 0.14 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 8/92 (8%) Query: 53 LRHSMAGTSARKSQRREEKRREEKR-REEKRREEKRREGKRREKEEEKEEEEEEEEEEEE 111 LRH + + + ++ K +E K + RR+ + + + +E EE E E+E+ Sbjct: 1341 LRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1400 Query: 112 -------EEEEEEEEEVSFSLATRERETETEE 136 ++ E EE + S+ + R + +E Sbjct: 1401 RPRTRSAKKAELEENQRSYKQKKKRRRIKVQE 1432 Score = 30.0 bits (66), Expect = 0.67 Identities = 15/41 (36%), Positives = 23/41 (56%) Query: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108 +++K R E + K EE+R+ RE+E EK E E E+ Sbjct: 1485 KDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED 1525 Score = 29.6 bits (65), Expect = 0.88 Identities = 12/46 (26%), Positives = 25/46 (54%) Query: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 E+ +++ E K+R GK+ E+ EE + + E + + EE ++ Sbjct: 1288 EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1333 Score = 29.3 bits (64), Expect = 1.1 Identities = 19/98 (19%), Positives = 42/98 (42%), Gaps = 4/98 (4%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRR----EEKRREEKRREEKR 87 +R NL+ N+ + + + +K QR K++ +EK+R R KR Sbjct: 1136 ERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKR 1195 Query: 88 REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125 ++ E++++ E +E++ + V+ +L Sbjct: 1196 KQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENL 1233 Score = 29.3 bits (64), Expect = 1.1 Identities = 16/67 (23%), Positives = 30/67 (44%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 K EE + E+ +++ EGK+R ++ +E +EE + + E + + E S Sbjct: 1273 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1332 Query: 124 SLATRER 130 R R Sbjct: 1333 KPRYRHR 1339 Score = 28.1 bits (61), Expect = 2.6 Identities = 18/106 (16%), Positives = 44/106 (41%), Gaps = 4/106 (3%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAG----TSARKSQRREEKRREEKRREEKRREEKRRE 89 E+L + +V +E T H + T ARK ++ +++ + E + K+ + Sbjct: 411 EDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVD 470 Query: 90 GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135 + + EE+ + E ++ + +EE + A + + + Sbjct: 471 SEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMD 516 Score = 26.6 bits (57), Expect = 7.4 Identities = 23/108 (21%), Positives = 46/108 (42%), Gaps = 5/108 (4%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 KR L G ++ T ++SM S +R +R E R E+R +R K Sbjct: 1092 KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKR--LKRIELR--ERRNLSSKRNTK 1147 Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERET-ETEEKR 138 + + EE E+ +++++ ++ + + ++R + T KR Sbjct: 1148 EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKR 1195 >gi|58761548 tau tubulin kinase 1 [Homo sapiens] Length = 1321 Score = 63.2 bits (152), Expect = 7e-11 Identities = 30/49 (61%), Positives = 38/49 (77%) Query: 81 KRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRE 129 K EE+ E + E+E+E+EEEEEEEEEEEEEEEEEEEEE + ++A E Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGE 780 Score = 58.2 bits (139), Expect = 2e-09 Identities = 30/53 (56%), Positives = 37/53 (69%), Gaps = 7/53 (13%) Query: 85 EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEK 137 + + GK E+EEE++EEEEEE+EEEEEEEEEEEEE E E E EE+ Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEE-------EEEEEEEEEE 771 Score = 57.8 bits (138), Expect = 3e-09 Identities = 28/47 (59%), Positives = 35/47 (74%) Query: 79 EEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125 +E+ EE+ E + E EEE+EEEEEEEEEEEEEEEEEEE + +L Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVAL 778 Score = 56.6 bits (135), Expect = 7e-09 Identities = 26/40 (65%), Positives = 33/40 (82%) Query: 78 REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117 +EE+ EE+ E + ++EEE+EEEEEEEEEEEEEEEEEE Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771 Score = 56.2 bits (134), Expect = 9e-09 Identities = 29/60 (48%), Positives = 36/60 (60%) Query: 77 RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEE 136 + EE+ EE E + E+EEE+EEEEEEEEEEEEEEEEE V+ R + E Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSE 791 Score = 53.9 bits (128), Expect = 4e-08 Identities = 25/40 (62%), Positives = 31/40 (77%) Query: 76 KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEE 115 K EE+ E++ E + E+EEE+EEEEEEEEEEEEEEEE Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771 Score = 52.4 bits (124), Expect = 1e-07 Identities = 24/40 (60%), Positives = 31/40 (77%) Query: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 +E+ EE+ EE+ E + E+EEE+EEEEEEEEEEEEEE Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771 Score = 51.2 bits (121), Expect = 3e-07 Identities = 28/58 (48%), Positives = 36/58 (62%), Gaps = 8/58 (13%) Query: 57 MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114 +A + + + EE+ EE EE+ EE E+EEE+EEEEEEEEEEEEEEE Sbjct: 722 LAPVQPQANGKEEEEEEEEDEEEEEEDEE--------EEEEEEEEEEEEEEEEEEEEE 771 Score = 28.5 bits (62), Expect = 2.0 Identities = 20/92 (21%), Positives = 34/92 (36%), Gaps = 15/92 (16%) Query: 64 KSQRREEKRREEKRREEKRREEKR---------------REGKRREKEEEKEEEEEEEEE 108 + EE+ EE+ EE+ EE+ R G E E + +E Sbjct: 746 EEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAP 805 Query: 109 EEEEEEEEEEEEVSFSLATRERETETEEKRLI 140 ++++E S+A + E E K L+ Sbjct: 806 STLLADDQKESRGRASMADGDLEPEEGSKTLV 837 >gi|21735569 claspin [Homo sapiens] Length = 1339 Score = 62.8 bits (151), Expect = 9e-11 Identities = 32/70 (45%), Positives = 48/70 (68%), Gaps = 1/70 (1%) Query: 69 EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEE-EEEEVSFSLAT 127 E+ EE+ EE+ +E +G+ + ++EEKEEE EEEEE+EEEEEEE +E F L++ Sbjct: 625 EDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSS 684 Query: 128 RERETETEEK 137 E ET+ E++ Sbjct: 685 EEIETKDEKE 694 Score = 44.7 bits (104), Expect = 3e-05 Identities = 24/74 (32%), Positives = 42/74 (56%) Query: 62 ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121 A+ + + +R EE+++ + + +G E+EEE+E +E EE+ EE+ E+EE+EE Sbjct: 599 AKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEE 658 Query: 122 SFSLATRERETETE 135 +E E E E Sbjct: 659 LEEEEEKEEEEEEE 672 Score = 43.9 bits (102), Expect = 5e-05 Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 5/84 (5%) Query: 55 HSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114 H+ G + + + ++ + +R EE+ +KR+ + + E+ EEEEEEEEE +E E Sbjct: 587 HTKPGEKLQVLKAKLQEAMKLRRFEER---QKRQALFKLDNEDGFEEEEEEEEEMTDESE 643 Query: 115 EEEEEEVSFSLATRERETETEEKR 138 E+ EE+V +E E E EE++ Sbjct: 644 EDGEEKV--EKEEKEEELEEEEEK 665 Score = 40.4 bits (93), Expect = 5e-04 Identities = 24/79 (30%), Positives = 41/79 (51%) Query: 59 GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 G S K + + + + + K R + R+ ++ + + E+ EEEEEEEEE +E E Sbjct: 584 GASHTKPGEKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESE 643 Query: 119 EEVSFSLATRERETETEEK 137 E+ + E+E E EE+ Sbjct: 644 EDGEEKVEKEEKEEELEEE 662 Score = 38.9 bits (89), Expect = 0.001 Identities = 23/87 (26%), Positives = 41/87 (47%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 KR+ L L N +EE + + + +E++ EE EE++ EE+ EG Sbjct: 615 KRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGN 674 Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEE 118 + E EE E ++E+E ++E + Sbjct: 675 QETAEFLLSSEEIETKDEKEMDKENND 701 Score = 38.1 bits (87), Expect = 0.002 Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 15/139 (10%) Query: 11 SSASSPENDRILLSTFPYPHSKREN----------LAGLTNSTSSVKEEPPTLRHSMAGT 60 SS P + + L + +P K E L N S ++E HS +G Sbjct: 968 SSMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDE-----HSDSGN 1022 Query: 61 SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 ++ E +R EK + + R ++ E + E+E + EE +E EE+ Sbjct: 1023 DLALEDHEDDDEEELLKRSEKLKRQMRLRKYLEDEAEVSGSDVGSEDEYDGEEIDEYEED 1082 Query: 121 VSFSLATRERETETEEKRL 139 V + + E +++ K++ Sbjct: 1083 VIDEVLPSDEELQSQIKKI 1101 Score = 37.0 bits (84), Expect = 0.006 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 22/120 (18%) Query: 41 NSTSSVKEEPPTLRH-----SMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREK 95 NST + + +H AG + KS+RR EK E+R+ EK R+ K++E K +E Sbjct: 140 NSTDFTTDRKSSKKHIHDKEGTAGKAKVKSKRRLEK---EERKMEKIRQLKKKETKNQED 196 Query: 96 EEEKE--------------EEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141 + E+ E E+E E+EE E + ++ + ++ + +E L S Sbjct: 197 DVEQPFNDSGCLLVDKDLFETGLEDENNSPLEDEESLESIRAAVKNKVKKHKKKEPSLES 256 Score = 27.3 bits (59), Expect = 4.4 Identities = 16/69 (23%), Positives = 33/69 (47%) Query: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133 ++ + EE+ E + R K R + E+ + ++ + EEEEE E+ F + ++ + Sbjct: 1157 DDDQTEEQLDESEARWRKERIEREQWLRDMAQQGKITAEEEEEIGEDSQFMILAKKVTAK 1216 Query: 134 TEEKRLISP 142 +K P Sbjct: 1217 ALQKNASRP 1225 Score = 26.2 bits (56), Expect = 9.7 Identities = 12/47 (25%), Positives = 26/47 (55%) Query: 93 REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 R+ ++++ EE+ +E E +E E E+ +A + + T EE+ + Sbjct: 1154 RDSDDDQTEEQLDESEARWRKERIEREQWLRDMAQQGKITAEEEEEI 1200 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 62.4 bits (150), Expect = 1e-10 Identities = 30/76 (39%), Positives = 47/76 (61%), Gaps = 5/76 (6%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 RK QRR E+ RE +R+ E++RE +R + R++E E+E E E E + E E + E+E E Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE-- 342 Query: 123 FSLATRERETETEEKR 138 R+R+TE + +R Sbjct: 343 ---RKRKRQTEMDRER 355 Score = 60.8 bits (146), Expect = 4e-10 Identities = 30/80 (37%), Positives = 45/80 (56%) Query: 59 GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 G R+ QR EK RE + E++R+ +R K RE+E+ ++E E E + E+E + E+ Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204 Query: 119 EEVSFSLATRERETETEEKR 138 RERETETE +R Sbjct: 205 HSERGRERERERETETETER 224 Score = 60.5 bits (145), Expect = 5e-10 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KE RHS G R+ +R E E KR+ ++ R+ +R+ + REK+ E+E E E Sbjct: 197 KENKTEDRHSERGRE-RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E ++E E E + + +ERE +T+ KR Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKR 287 Score = 57.4 bits (137), Expect = 4e-09 Identities = 28/76 (36%), Positives = 43/76 (56%), Gaps = 5/76 (6%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R+ +R + R+ +RR E+ RE +R+ ++RE+E E+E + E E E E E E + E Sbjct: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334 Query: 123 FSLATRERETETEEKR 138 R+RE E E KR Sbjct: 335 -----RDREKERERKR 345 Score = 57.0 bits (136), Expect = 5e-09 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 12/108 (11%) Query: 31 SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90 ++RE G T +E R A + RE +R+ E+ R+++R EK R+ Sbjct: 131 TEREGERGRDRQTDGQRERE---RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQ- 186 Query: 91 KRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 +RRE+E ++E+E + E+ E E E E RE ETETE KR Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERE--------RETETETERKR 226 Score = 57.0 bits (136), Expect = 5e-09 Identities = 27/76 (35%), Positives = 43/76 (56%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R+ QR+ E+ R+++R EK R+E+R ++REKE + E+ E E E E E E E Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETER 224 Query: 123 FSLATRERETETEEKR 138 RER+ + + +R Sbjct: 225 KRQTDRERDRQRKTER 240 Score = 55.1 bits (131), Expect = 2e-08 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 4/79 (5%) Query: 63 RKSQRREEKR---REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 ++ +RR EKR RE R+ E+RRE+ R + R +E +++ E+E E + + E + + E+ Sbjct: 60 KERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREK 119 Query: 120 EVSFSLATRERETETEEKR 138 E + RERETE E +R Sbjct: 120 ERNRQ-KERERETEREGER 137 Score = 53.1 bits (126), Expect = 7e-08 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Query: 63 RKSQRREEKRREEKRRE--EKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 R+++R EK RE KR+ E RE R+ G+ ++ E+E E E E + + E EE E Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390 Query: 121 VSFSLATRERETETEEKR 138 +ERE +TE+ R Sbjct: 391 DRDRDRQKERERQTEKDR 408 Score = 52.0 bits (123), Expect = 2e-07 Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Query: 54 RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 R + +K + RE+ R+E + RE +R +E + E + E+ E+E E E E E E + Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226 Query: 114 EEEEEEEVSFSLATRERETETEEKR 138 + + E + RERE + E +R Sbjct: 227 QTDRERDRQ-RKTEREREKQAERER 250 Score = 51.6 bits (122), Expect = 2e-07 Identities = 25/86 (29%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Query: 54 RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE-EEEE 112 R+ G R+ RE +R E+ R+ R E+R + R++++E+E + E++ + + E Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414 Query: 113 EEEEEEEEVSFSLATRERETETEEKR 138 E++ E E+ S RER E E+++ Sbjct: 415 EKQREREKDRESERGRERGREREKQK 440 Score = 50.8 bits (120), Expect = 4e-07 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 9/84 (10%) Query: 63 RKSQRREEKRREEKR---REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 RK +RR EK R KR RE +R EK RE ++ ++E +++ E+E ++E E E E E Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERE-RQTDRERDRQREKERNRQKERERETEREG 135 Query: 120 EVSFSLAT-----RERETETEEKR 138 E T RER+ + E++R Sbjct: 136 ERGRDRQTDGQRERERQRDAEKER 159 Score = 50.8 bits (120), Expect = 4e-07 Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 5/112 (4%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 +RE N T E R T ++R+ R +++R+ +R EK+ E + Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249 Query: 92 R---REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATR--ERETETEEKR 138 R RE E +KE E E + + + + ++E E + R ER+ ETE KR Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301 Score = 50.8 bits (120), Expect = 4e-07 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 16/88 (18%) Query: 63 RKSQRREEKRREEKRREEKRREEKR---------------REGKRREKEEEKEEEEEEEE 107 R+ +R E++RE +R EK RE KR REG RR+ E E+E E E + Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG-RRQAERERERERERDR 379 Query: 108 EEEEEEEEEEEEEVSFSLATRERETETE 135 + E EE E + RER+TE + Sbjct: 380 QSAREREERERDRDRDRQKERERQTEKD 407 Score = 50.4 bits (119), Expect = 5e-07 Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 4/83 (4%) Query: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKR-REKEEEKEEEEEEEEEEEEEEEEEEE 118 T ++ ++RE +R E+ R+ +R E+ RE +R RE E ++E+E E + + + E + E Sbjct: 297 TERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERN 356 Query: 119 EEVSFS---LATRERETETEEKR 138 + A RERE E E R Sbjct: 357 RQTGREGRRQAERERERERERDR 379 Score = 49.7 bits (117), Expect = 8e-07 Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 3/79 (3%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE---EEEEEEEEEEEEEEEEE 119 R+ R +E+ R+ R +++RE++R K RE+E E+E E + + + + E E + + E Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156 Query: 120 EVSFSLATRERETETEEKR 138 + RER+ +TE R Sbjct: 157 KERERQTDRERQRQTERNR 175 Score = 49.7 bits (117), Expect = 8e-07 Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 12/83 (14%) Query: 61 SARKSQRREEKRREEKRREEKRREEKRREGKR-----REKEEEKEEEEEEEEEEEEEEEE 115 SAR+ + RE R ++++E +R+ EK R+G+R RE+E+++E E E E E+++ Sbjct: 381 SAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK 440 Query: 116 EEEEEVSFSLATRERETETEEKR 138 E + RER+T+ + R Sbjct: 441 GRERD-------RERQTDRQAGR 456 Score = 48.9 bits (115), Expect = 1e-06 Identities = 25/81 (30%), Positives = 46/81 (56%), Gaps = 10/81 (12%) Query: 61 SARKSQRREEKRREEKR---REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117 S R+++R +E+ RE R R+ +++E +R+ ++R++ E++ E E + E + E E E Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311 Query: 118 EEEVSFSLATRERETETEEKR 138 E R+RE E E +R Sbjct: 312 ERN-------RKRERERERER 325 Score = 47.8 bits (112), Expect = 3e-06 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 13/86 (15%) Query: 63 RKSQRREEKRREEKRREEKRRE-EKRREGKR---------REKEEEKEEEEEEEEEEEEE 112 R++ R +++RE++R +K RE E REG+R RE+E +++ E+E E + + E Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166 Query: 113 EEEEEEEEVSFSLATRERETETEEKR 138 + + E RERE +E+R Sbjct: 167 RQRQTERN---RQKEREREKNRQERR 189 Score = 47.0 bits (110), Expect = 5e-06 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 6/86 (6%) Query: 54 RHSMAGTSARKSQRREEKRREEKRREEKRREEK-RREGKRREKEEEKEEEEEEEEEEEEE 112 RH + + RE++R + RE R+ EK R K RE+E E+E E + + + + Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146 Query: 113 EEEEEEEEVSFSLATRERETETEEKR 138 E E + + A +ERE +T+ +R Sbjct: 147 RERERQRD-----AEKERERQTDRER 167 Score = 47.0 bits (110), Expect = 5e-06 Identities = 19/76 (25%), Positives = 41/76 (53%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 RK++R EK+ E +R E+ E + + R+++ +++ ++E E + + + + E Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295 Query: 123 FSLATRERETETEEKR 138 + RER+ E E +R Sbjct: 296 ETERKRERQRERERER 311 Score = 46.6 bits (109), Expect = 7e-06 Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 8/85 (9%) Query: 54 RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 RH K + R+ R +++RE++R +K RE + E+E E+ + + + + E E Sbjct: 93 RHRERQRDREKERERQTDRERDRQREKERNRQKERE-RETEREGERGRDRQTDGQRERER 151 Query: 114 EEEEEEEVSFSLATRERETETEEKR 138 + + E+E RER+T+ E +R Sbjct: 152 QRDAEKE-------RERQTDRERQR 169 Score = 38.1 bits (87), Expect = 0.002 Identities = 21/64 (32%), Positives = 38/64 (59%), Gaps = 4/64 (6%) Query: 63 RKSQRREEKRREEKRREEKRRE-EKRRE---GKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 ++ +R+ EK R+ +R EK+RE EK RE G+ R +E EK++ E + E + + + + Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457 Query: 119 EEVS 122 + S Sbjct: 458 RKRS 461 Score = 36.6 bits (83), Expect = 0.007 Identities = 20/72 (27%), Positives = 32/72 (44%) Query: 67 RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126 RR +E RR + K +G RE+ +KE E E+ + E E + + E Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87 Query: 127 TRERETETEEKR 138 R+R+ E +R Sbjct: 88 HRKRDRHRERQR 99 Score = 34.7 bits (78), Expect = 0.027 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Query: 61 SARKSQRREEKRREEKRREEKRRE-EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 S R+ +E RR + K + + R +++E+E +E+ + E E + + E E++ Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86 Query: 120 EVSFSLATRERETETEEKR 138 RER+ + E++R Sbjct: 87 RHRKRDRHRERQRDREKER 105 >gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo sapiens] Length = 1108 Score = 61.6 bits (148), Expect = 2e-10 Identities = 44/115 (38%), Positives = 58/115 (50%), Gaps = 13/115 (11%) Query: 28 YPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQ----RREEKRREEKRREEKRR 83 Y + KRE A +ST + P L + G A SQ RE REE EK Sbjct: 967 YSYCKRE--AEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEE 1024 Query: 84 EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 EE+ +E + ++E+E E+ + +EEEEEEEEE EEEE E E E EE + Sbjct: 1025 EEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEE-------VEEAENEGEEAK 1072 Score = 28.9 bits (63), Expect = 1.5 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 3/92 (3%) Query: 54 RHSMAGT-SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112 R S +G+ S + R +RE + R+ +EE E E + + + +E E Sbjct: 952 RFSHSGSYSQHMNHRYSYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERES 1011 Query: 113 --EEEEEEEEVSFSLATRERETETEEKRLISP 142 EE+E+ E +E E EEK P Sbjct: 1012 LTREEDEDSEKEEEEEDKEMEELQEEKECEKP 1043 Score = 27.7 bits (60), Expect = 3.3 Identities = 25/107 (23%), Positives = 42/107 (39%), Gaps = 10/107 (9%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 +RE+L + S +EE M K + + EE+ EE+ EE Sbjct: 1008 ERESLTREEDEDSEKEEEEED--KEMEELQEEKECEKPQGDEEEEEEEEEVEEE------ 1059 Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E EE + E EE + E +++ E + S E + E++ Sbjct: 1060 --EVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEK 1104 >gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo sapiens] Length = 1124 Score = 61.6 bits (148), Expect = 2e-10 Identities = 44/115 (38%), Positives = 58/115 (50%), Gaps = 13/115 (11%) Query: 28 YPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQ----RREEKRREEKRREEKRR 83 Y + KRE A +ST + P L + G A SQ RE REE EK Sbjct: 983 YSYCKRE--AEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEE 1040 Query: 84 EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 EE+ +E + ++E+E E+ + +EEEEEEEEE EEEE E E E EE + Sbjct: 1041 EEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEE-------VEEAENEGEEAK 1088 Score = 28.9 bits (63), Expect = 1.5 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 3/92 (3%) Query: 54 RHSMAGT-SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112 R S +G+ S + R +RE + R+ +EE E E + + + +E E Sbjct: 968 RFSHSGSYSQHMNHRYSYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERES 1027 Query: 113 --EEEEEEEEVSFSLATRERETETEEKRLISP 142 EE+E+ E +E E EEK P Sbjct: 1028 LTREEDEDSEKEEEEEDKEMEELQEEKECEKP 1059 Score = 27.7 bits (60), Expect = 3.3 Identities = 25/107 (23%), Positives = 42/107 (39%), Gaps = 10/107 (9%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 +RE+L + S +EE M K + + EE+ EE+ EE Sbjct: 1024 ERESLTREEDEDSEKEEEEED--KEMEELQEEKECEKPQGDEEEEEEEEEVEEE------ 1075 Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E EE + E EE + E +++ E + S E + E++ Sbjct: 1076 --EVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEK 1120 >gi|118498345 AT-binding transcription factor 1 [Homo sapiens] Length = 3703 Score = 61.2 bits (147), Expect = 3e-10 Identities = 49/131 (37%), Positives = 69/131 (52%), Gaps = 12/131 (9%) Query: 12 SASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTL--RHSMAGTSARKSQRRE 69 SA+ PE + L T S NL GLT SSV + P T +A + + S+ ++ Sbjct: 383 SAAGPEQPQAGLLT----PSTLLNLGGLT---SSVLKTPITSVPLGPLASSPTKSSEGKD 435 Query: 70 EKRREEKRREEKRRE---EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126 E +++E + EK + +EEE+EEE EEEEEEEEEEEEEEE+E L Sbjct: 436 SGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLF 495 Query: 127 TRERETETEEK 137 E + E E++ Sbjct: 496 PSELDEELEDR 506 Score = 29.6 bits (65), Expect = 0.88 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 58 AGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEE 110 A A + + EE EE+ EE+ EE+ EG + E +EE E+ EE Sbjct: 459 AEEEAEEEEEEEEAEEEEEEEEEE-EEEEEDEGCKGLFPSELDEELEDRPHEE 510 Score = 29.3 bits (64), Expect = 1.1 Identities = 23/112 (20%), Positives = 52/112 (46%), Gaps = 6/112 (5%) Query: 26 FPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREE 85 FPY + + L GL S S+ ++ + S+ ++ QR+ ++++++K ++++ + Sbjct: 3342 FPYSPALSQALMGL--SPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKAS 3399 Query: 86 KRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEK 137 + +++ +E + EE++ EVS L E E E K Sbjct: 3400 QTPV----PPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESK 3447 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 61.2 bits (147), Expect = 3e-10 Identities = 37/97 (38%), Positives = 52/97 (53%), Gaps = 3/97 (3%) Query: 40 TNSTSSVKEEPPTLRHSM---AGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE 96 + S+ S KEE + + G+S ++ EE+ EE E++ E E E Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDE 223 Query: 97 EEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133 E E+ EEEEEEEEEEEEEEEEEE + R+++ E Sbjct: 224 EVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260 Score = 53.5 bits (127), Expect = 6e-08 Identities = 25/61 (40%), Positives = 39/61 (63%) Query: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133 EE + + EE +G+ E+EEE+EEEEEEEEEEE E++E +++E TR ++ Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272 Query: 134 T 134 + Sbjct: 273 S 273 Score = 49.3 bits (116), Expect = 1e-06 Identities = 24/67 (35%), Positives = 40/67 (59%) Query: 69 EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATR 128 EE E+ EE ++ E + E+EEE+EEEEEEEEE E++E +++EE + + Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269 Query: 129 ERETETE 135 ++ +E Sbjct: 270 ASDSGSE 276 Score = 46.2 bits (108), Expect = 9e-06 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 7/82 (8%) Query: 63 RKSQRREEKRREEKRREEKRREEKR-------REGKRREKEEEKEEEEEEEEEEEEEEEE 115 R++ R + +EE EE + + +G E EEE EE+ EE+EE EE+ E Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220 Query: 116 EEEEEVSFSLATRERETETEEK 137 E+EE E E E EE+ Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEE 242 Score = 40.0 bits (92), Expect = 7e-04 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 10/91 (10%) Query: 62 ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121 A + + +E EE+ EE+ EE+ E + E++E ++EE + + E + E V Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278 Query: 122 SF----------SLATRERETETEEKRLISP 142 SF + + E++ E + R ISP Sbjct: 279 SFTDGSVRSGSGTDGSDEKKKERKRARGISP 309 Score = 38.9 bits (89), Expect = 0.001 Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Query: 53 LRHSMAGTSARKSQRREEKR-REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE 109 LR + A S R+S+ RE R RE R + RR+ +R G+ RE+E E+ + + + E Sbjct: 646 LRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGE 703 Score = 30.0 bits (66), Expect = 0.67 Identities = 32/140 (22%), Positives = 58/140 (41%), Gaps = 9/140 (6%) Query: 6 HSRGFSS---ASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSA 62 HSR S +SS N++ ++ST ++ +N + + + +R S + S Sbjct: 65 HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLS-SSASR 123 Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRR-----EKEEEKEEEEEEEEEEEEEEEEEE 117 + + EK KR E+R + +G R ++ + + +EE EE + Sbjct: 124 EPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDH 183 Query: 118 EEEVSFSLATRERETETEEK 137 E S S + TE EE+ Sbjct: 184 ETGSSGSSDEQGNNTENEEE 203 Score = 29.3 bits (64), Expect = 1.1 Identities = 19/67 (28%), Positives = 25/67 (37%) Query: 70 EKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRE 129 E R R + +EE E + E +E+ E EEE EE+V E Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217 Query: 130 RETETEE 136 E EE Sbjct: 218 DAEEDEE 224 Score = 28.1 bits (61), Expect = 2.6 Identities = 25/121 (20%), Positives = 37/121 (30%), Gaps = 14/121 (11%) Query: 31 SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90 + RE T K +P S + + ++R + K G Sbjct: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180 Query: 91 KRREKEEEKEEEEEEEEEEEEEE--------------EEEEEEEVSFSLATRERETETEE 136 E +E+ E EEE + EE+EEV E E E EE Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240 Query: 137 K 137 + Sbjct: 241 E 241 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 61.2 bits (147), Expect = 3e-10 Identities = 37/97 (38%), Positives = 52/97 (53%), Gaps = 3/97 (3%) Query: 40 TNSTSSVKEEPPTLRHSM---AGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE 96 + S+ S KEE + + G+S ++ EE+ EE E++ E E E Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDE 223 Query: 97 EEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133 E E+ EEEEEEEEEEEEEEEEEE + R+++ E Sbjct: 224 EVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260 Score = 53.5 bits (127), Expect = 6e-08 Identities = 25/61 (40%), Positives = 39/61 (63%) Query: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133 EE + + EE +G+ E+EEE+EEEEEEEEEEE E++E +++E TR ++ Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272 Query: 134 T 134 + Sbjct: 273 S 273 Score = 49.3 bits (116), Expect = 1e-06 Identities = 24/67 (35%), Positives = 40/67 (59%) Query: 69 EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATR 128 EE E+ EE ++ E + E+EEE+EEEEEEEEE E++E +++EE + + Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269 Query: 129 ERETETE 135 ++ +E Sbjct: 270 ASDSGSE 276 Score = 46.2 bits (108), Expect = 9e-06 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 7/82 (8%) Query: 63 RKSQRREEKRREEKRREEKRREEKR-------REGKRREKEEEKEEEEEEEEEEEEEEEE 115 R++ R + +EE EE + + +G E EEE EE+ EE+EE EE+ E Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220 Query: 116 EEEEEVSFSLATRERETETEEK 137 E+EE E E E EE+ Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEE 242 Score = 40.0 bits (92), Expect = 7e-04 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 10/91 (10%) Query: 62 ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121 A + + +E EE+ EE+ EE+ E + E++E ++EE + + E + E V Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278 Query: 122 SF----------SLATRERETETEEKRLISP 142 SF + + E++ E + R ISP Sbjct: 279 SFTDGSVRSGSGTDGSDEKKKERKRARGISP 309 Score = 38.9 bits (89), Expect = 0.001 Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Query: 53 LRHSMAGTSARKSQRREEKR-REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE 109 LR + A S R+S+ RE R RE R + RR+ +R G+ RE+E E+ + + + E Sbjct: 664 LRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGE 721 Score = 30.0 bits (66), Expect = 0.67 Identities = 32/140 (22%), Positives = 58/140 (41%), Gaps = 9/140 (6%) Query: 6 HSRGFSS---ASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSA 62 HSR S +SS N++ ++ST ++ +N + + + +R S + S Sbjct: 65 HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLS-SSASR 123 Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRR-----EKEEEKEEEEEEEEEEEEEEEEEE 117 + + EK KR E+R + +G R ++ + + +EE EE + Sbjct: 124 EPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDH 183 Query: 118 EEEVSFSLATRERETETEEK 137 E S S + TE EE+ Sbjct: 184 ETGSSGSSDEQGNNTENEEE 203 Score = 29.3 bits (64), Expect = 1.1 Identities = 19/67 (28%), Positives = 25/67 (37%) Query: 70 EKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRE 129 E R R + +EE E + E +E+ E EEE EE+V E Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217 Query: 130 RETETEE 136 E EE Sbjct: 218 DAEEDEE 224 Score = 28.1 bits (61), Expect = 2.6 Identities = 25/121 (20%), Positives = 37/121 (30%), Gaps = 14/121 (11%) Query: 31 SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90 + RE T K +P S + + ++R + K G Sbjct: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180 Query: 91 KRREKEEEKEEEEEEEEEEEEEE--------------EEEEEEEVSFSLATRERETETEE 136 E +E+ E EEE + EE+EEV E E E EE Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240 Query: 137 K 137 + Sbjct: 241 E 241 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 60.8 bits (146), Expect = 4e-10 Identities = 26/84 (30%), Positives = 50/84 (59%) Query: 55 HSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114 H + R+S+R++E+R EKR+ E+ +E KR GK+ +K+ +K E +E E + +E E Sbjct: 24 HISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83 Query: 115 EEEEEEVSFSLATRERETETEEKR 138 ++ +E R++E + E++ Sbjct: 84 KQRKERREKERRKRKKEKKKRERK 107 Score = 58.9 bits (141), Expect = 1e-09 Identities = 30/107 (28%), Positives = 56/107 (52%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 KRE KE R + ++ +RR++KRR+E++RE++R + +R+ K Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162 Query: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 R+++E EK+ E +E ++E E +E E R ++ E ++ R Sbjct: 163 RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209 Score = 56.2 bits (134), Expect = 9e-09 Identities = 28/92 (30%), Positives = 56/92 (60%), Gaps = 1/92 (1%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KE+ R +K + R+E+ RE K+R E++R+ KRR+ KRR++ + ++E + E Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK-KRRKKKRRKERKREKERGKRE 157 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 + ++ ++EE E++ + R++E E +E+R Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKERR 189 Score = 55.8 bits (133), Expect = 1e-08 Identities = 25/90 (27%), Positives = 52/90 (57%) Query: 49 EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108 +P T R S R+ ++R+ +R +E++RE ++E+K+R+ + R KE E++ +E E++ Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86 Query: 109 EEEEEEEEEEEEVSFSLATRERETETEEKR 138 +E E+E + + R++ E K+ Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKK 116 Score = 54.7 bits (130), Expect = 3e-08 Identities = 24/75 (32%), Positives = 49/75 (65%), Gaps = 3/75 (4%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R+ +R+ E+ ++EK++ +KR K RE KR+E+E++++E E+E + ++E+++ E + Sbjct: 50 REKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK-- 107 Query: 123 FSLATRERETETEEK 137 RER+ + E K Sbjct: 108 -QRGRRERKKKKERK 121 Score = 53.5 bits (127), Expect = 6e-08 Identities = 24/76 (31%), Positives = 46/76 (60%), Gaps = 5/76 (6%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 RK + ++ K R EK R ++++E+K+RE K+R + E K+++E +E E E ++ E + + Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK-- 136 Query: 123 FSLATRERETETEEKR 138 R+++ E KR Sbjct: 137 ---KRRKKKRRKERKR 149 Score = 52.8 bits (125), Expect = 1e-07 Identities = 29/95 (30%), Positives = 54/95 (56%), Gaps = 3/95 (3%) Query: 47 KEEPPTLRHSMAGTSARKSQRREE--KRREEKRRE-EKRREEKRREGKRREKEEEKEEEE 103 K E R G +K +++ E K RE KR+E EK+R+E+R + +R+ K+E+K+ E Sbjct: 47 KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRER 106 Query: 104 EEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 ++ E ++++E +E + RER+ + K+ Sbjct: 107 KQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141 Score = 52.4 bits (124), Expect = 1e-07 Identities = 24/78 (30%), Positives = 49/78 (62%), Gaps = 2/78 (2%) Query: 63 RKSQRRE--EKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 R+ QR+E EK R ++++E+K+RE K+R + R+K++E++E E E ++ E + ++ ++ Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141 Query: 121 VSFSLATRERETETEEKR 138 RE+E E++ Sbjct: 142 KRRKERKREKERGKRERK 159 Score = 52.4 bits (124), Expect = 1e-07 Identities = 22/76 (28%), Positives = 46/76 (60%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R+ ++R ++R+ EK R ++ R+ K+R+ + REK+ E+ +E ++E E +E E ++E Sbjct: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197 Query: 123 FSLATRERETETEEKR 138 +ER+ + + R Sbjct: 198 ERRKKKERKKDRKTDR 213 Score = 52.4 bits (124), Expect = 1e-07 Identities = 21/75 (28%), Positives = 48/75 (64%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 RK ++RE++R + +R+ +KR++E+R + + R ++E K+E E +E E ++E ++E + Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203 Query: 123 FSLATRERETETEEK 137 R+ + +T+ + Sbjct: 204 ERKKDRKTDRQTDSQ 218 Score = 48.1 bits (113), Expect = 2e-06 Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 7/83 (8%) Query: 63 RKSQRREEKRREEK---RREEKR---REEKRREGK-RREKEEEKEEEEEEEEEEEEEEEE 115 R+ +++E+K+RE K RRE K+ R+E+ RE K RRE++ +K +++ +E + E+E Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153 Query: 116 EEEEEVSFSLATRERETETEEKR 138 + E ERE + E R Sbjct: 154 GKRERKRKKRKKEEREKKRERNR 176 Score = 48.1 bits (113), Expect = 2e-06 Identities = 22/75 (29%), Positives = 48/75 (64%), Gaps = 2/75 (2%) Query: 54 RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 R G RK ++R+++ RE+KR E+ R+E+++E +R+E+ E K+E ++E +++E + Sbjct: 149 REKERGKRERKRKKRKKEEREKKR--ERNRKERKKERERKERRERKKERKKERRKKKERK 206 Query: 114 EEEEEEEVSFSLATR 128 ++ + + + S R Sbjct: 207 KDRKTDRQTDSQVFR 221 Score = 33.5 bits (75), Expect = 0.061 Identities = 16/71 (22%), Positives = 32/71 (45%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 KRE G +++ + RK +R ++RRE K+ +K R +K+ K Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207 Query: 92 RREKEEEKEEE 102 R+ + + + + Sbjct: 208 DRKTDRQTDSQ 218 >gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] Length = 185 Score = 60.8 bits (146), Expect = 4e-10 Identities = 33/63 (52%), Positives = 43/63 (68%), Gaps = 3/63 (4%) Query: 79 EEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRER---ETETE 135 EE+ EE+ E + EKEEEKEE+EEEEE+EEE+EE+EEEEE E+ E +TE Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178 Query: 136 EKR 138 +R Sbjct: 179 IQR 181 Score = 57.8 bits (138), Expect = 3e-09 Identities = 27/55 (49%), Positives = 39/55 (70%) Query: 66 QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 + E + EE+ EE++ EEK + + EKEEEKEE+EEEEE+E ++ EEE+ EE Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173 Score = 55.5 bits (132), Expect = 1e-08 Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 1/65 (1%) Query: 70 EKRREEKRREEKRREEKRREGKRREKEEEKEEE-EEEEEEEEEEEEEEEEEEVSFSLATR 128 E+ E+ EE EEK E + E+EEEKEEE EE+EEEEE+E ++ EEE+V + T Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178 Query: 129 ERETE 133 + T+ Sbjct: 179 IQRTQ 183 Score = 53.9 bits (128), Expect = 4e-08 Identities = 25/67 (37%), Positives = 44/67 (65%) Query: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133 EE+ EE+ E + E + ++E+E+EEE+EEE+EE+EEEEE+E +++ E +TE Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178 Query: 134 TEEKRLI 140 + + + Sbjct: 179 IQRTQYL 185 Score = 46.6 bits (109), Expect = 7e-06 Identities = 24/53 (45%), Positives = 37/53 (69%), Gaps = 2/53 (3%) Query: 69 EEKRREEKRREEKRREEKRREGKRREKEE--EKEEEEEEEEEEEEEEEEEEEE 119 EE+ EE+ +EE++ E++ E K EKEE E+EE+E ++ EEE+ EEE + E Sbjct: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178 Score = 44.7 bits (104), Expect = 3e-05 Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 1/55 (1%) Query: 69 EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 EE+ +EE++ E++ EEK E K ++EEE++E ++ EEE+ EEE + E + + Sbjct: 131 EEEEKEEEKEEDEEEEEKEEE-KEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQY 184 Score = 43.9 bits (102), Expect = 5e-05 Identities = 23/76 (30%), Positives = 37/76 (48%) Query: 37 AGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE 96 A L S ++ P + + +E+ +EE EE++ EEK + + EKE Sbjct: 103 AALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162 Query: 97 EEKEEEEEEEEEEEEE 112 +K EEE+ EEE + E Sbjct: 163 GKKMEEEKVEEEIDTE 178 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 60.5 bits (145), Expect = 5e-10 Identities = 36/132 (27%), Positives = 68/132 (51%), Gaps = 11/132 (8%) Query: 7 SRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQ 66 SR + + S + DR + PH KR S S + ++ + Sbjct: 335 SRSHNRSRSRQKDRRRSKS---PHKKRSKSRERRKSRSRSHSRD---KRKDTREKIKEKE 388 Query: 67 RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126 R +EK RE++R EK RE+++ GK +++++E+E++ E+++E++ E E E+E E Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE-----K 443 Query: 127 TRERETETEEKR 138 R++E E E+ + Sbjct: 444 DRDKEKEKEQDK 455 Score = 53.1 bits (126), Expect = 7e-08 Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 8/138 (5%) Query: 6 HSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKS 65 H+R S +SS + R S H R + + + + P + S + RKS Sbjct: 311 HTRSKSRSSSKSHSRRKRSQSK--HRSRSHNRSRSRQKDRRRSKSPHKKRSKS-RERRKS 367 Query: 66 QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE-EEEEE----EEEEEEEEEEEEE 120 + R R + K EK +E++R + K REKE E+E+E E+E+E ++ ++E E++ E+ Sbjct: 368 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK 427 Query: 121 VSFSLATRERETETEEKR 138 RERE E E+ R Sbjct: 428 DKEKDREREREKEHEKDR 445 Score = 51.2 bits (121), Expect = 3e-07 Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 10/89 (11%) Query: 59 GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 G + + + RE+ R ++K ++ +R EK E K R+KE+EKE+++E+E E++ +E +E+ Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKEHE-KDRDKEKEKEQDKEKEREKDRSKEIDEK 470 Query: 119 EEV---------SFSLATRERETETEEKR 138 + S++ + R R + E +R Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRR 499 Score = 42.7 bits (99), Expect = 1e-04 Identities = 25/112 (22%), Positives = 57/112 (50%), Gaps = 3/112 (2%) Query: 31 SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90 S RE + S+S T++ + + + +S+ +++K+RE++R R E+ R Sbjct: 493 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERST 552 Query: 91 KRREKEEEKEEEEEEEEEEE--EEEEEEEEEEVSFSLATRERET-ETEEKRL 139 R+ +++ +E+ E+ +E+E +E + S S +++ TEE ++ Sbjct: 553 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 604 Score = 36.2 bits (82), Expect = 0.009 Identities = 18/91 (19%), Positives = 39/91 (42%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 K P ++ + S S+ R +R R + + +R+ R + +++++ Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 535 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEK 137 E+E + E E E S S+ + + +EK Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKEK 566 Score = 30.0 bits (66), Expect = 0.67 Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 7/78 (8%) Query: 61 SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 ++R+S+ +RR + R R + KR+ +++++ E+E + E Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 545 Query: 121 VSFSLATRERETETEEKR 138 RERE T ++ Sbjct: 546 -------RERERSTSMRK 556 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 60.5 bits (145), Expect = 5e-10 Identities = 36/132 (27%), Positives = 68/132 (51%), Gaps = 11/132 (8%) Query: 7 SRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQ 66 SR + + S + DR + PH KR S S + ++ + Sbjct: 219 SRSHNRSRSRQKDRRRSKS---PHKKRSKSRERRKSRSRSHSRD---KRKDTREKIKEKE 272 Query: 67 RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126 R +EK RE++R EK RE+++ GK +++++E+E++ E+++E++ E E E+E E Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE-----K 327 Query: 127 TRERETETEEKR 138 R++E E E+ + Sbjct: 328 DRDKEKEKEQDK 339 Score = 53.1 bits (126), Expect = 7e-08 Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 8/138 (5%) Query: 6 HSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKS 65 H+R S +SS + R S H R + + + + P + S + RKS Sbjct: 195 HTRSKSRSSSKSHSRRKRSQSK--HRSRSHNRSRSRQKDRRRSKSPHKKRSKS-RERRKS 251 Query: 66 QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE-EEEEE----EEEEEEEEEEEEE 120 + R R + K EK +E++R + K REKE E+E+E E+E+E ++ ++E E++ E+ Sbjct: 252 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK 311 Query: 121 VSFSLATRERETETEEKR 138 RERE E E+ R Sbjct: 312 DKEKDREREREKEHEKDR 329 Score = 51.2 bits (121), Expect = 3e-07 Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 10/89 (11%) Query: 59 GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 G + + + RE+ R ++K ++ +R EK E K R+KE+EKE+++E+E E++ +E +E+ Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREKEHE-KDRDKEKEKEQDKEKEREKDRSKEIDEK 354 Query: 119 EEV---------SFSLATRERETETEEKR 138 + S++ + R R + E +R Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRR 383 Score = 42.7 bits (99), Expect = 1e-04 Identities = 25/112 (22%), Positives = 57/112 (50%), Gaps = 3/112 (2%) Query: 31 SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90 S RE + S+S T++ + + + +S+ +++K+RE++R R E+ R Sbjct: 377 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERST 436 Query: 91 KRREKEEEKEEEEEEEEEEE--EEEEEEEEEEVSFSLATRERET-ETEEKRL 139 R+ +++ +E+ E+ +E+E +E + S S +++ TEE ++ Sbjct: 437 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 488 Score = 36.2 bits (82), Expect = 0.009 Identities = 18/91 (19%), Positives = 39/91 (42%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 K P ++ + S S+ R +R R + + +R+ R + +++++ Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 419 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEK 137 E+E + E E E S S+ + + +EK Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKEK 450 Score = 30.0 bits (66), Expect = 0.67 Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 7/78 (8%) Query: 61 SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 ++R+S+ +RR + R R + KR+ +++++ E+E + E Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 429 Query: 121 VSFSLATRERETETEEKR 138 RERE T ++ Sbjct: 430 -------RERERSTSMRK 440 >gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4 isoform 3 [Homo sapiens] Length = 1212 Score = 60.1 bits (144), Expect = 6e-10 Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 12/107 (11%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRR--EEKRREEKRREEKRREGKRREKEEE----- 98 ++E+ R +A R Q++E++RR E++RRE + R ++ RE +RRE+EE+ Sbjct: 381 LREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEE 440 Query: 99 -----KEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140 KEEEE EEE+ E E+E + L +R E +++L+ Sbjct: 441 LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487 Score = 47.0 bits (110), Expect = 5e-06 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 16/103 (15%) Query: 52 TLRHSMAGTSARKSQRREEKRREEKRREEKRRE----------------EKRREGKRREK 95 TLR +R E RR++ +E++ RE E+++E +RR + Sbjct: 351 TLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE 410 Query: 96 EEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+++ E E ++E E+ E+EE+ R R+ E E +R Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453 Score = 42.7 bits (99), Expect = 1e-04 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KE LR ++ Q RE++ + + E+++ ++++ +RR EE++ E E Sbjct: 364 KERSEALRRQQL---LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR 420 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 ++E E+ E+EE R E EE+R Sbjct: 421 RQQEREQRRREQEEKRRLEELERRRKEEEERR 452 Score = 40.4 bits (93), Expect = 5e-04 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 10/99 (10%) Query: 49 EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE------- 101 EP ++ + ++ R+ R ++ +E R E RR++ +E + RE+EE K + Sbjct: 339 EPSSIVNVPGESTLRRDFLRLQQENKE-RSEALRRQQLLQEQQLREQEEYKRQLLAERQK 397 Query: 102 --EEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+++E+ EE++ E E +R E EEKR Sbjct: 398 RIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436 Score = 34.3 bits (77), Expect = 0.036 Identities = 18/48 (37%), Positives = 26/48 (54%) Query: 73 REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 R++ + R + K + R+K EK+E E E EEEEEE E+E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE 337 Score = 32.3 bits (72), Expect = 0.14 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Query: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 R++ + R + K ++ R+ KR EK+E + E EEEEEE E+E E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRK-KRGEKDETEYEYSGSEEEEEEVPEQEGE 339 Score = 30.0 bits (66), Expect = 0.67 Identities = 18/50 (36%), Positives = 24/50 (48%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 + Q E + R + + R +KR E E E EEEEEE E+E E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339 Score = 28.1 bits (61), Expect = 2.6 Identities = 17/56 (30%), Positives = 26/56 (46%) Query: 53 LRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108 L+H + Q R + + R +KR E+ E + EEE+EE E+E E Sbjct: 284 LKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339 >gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 [Homo sapiens] Length = 1166 Score = 60.1 bits (144), Expect = 6e-10 Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 12/107 (11%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRR--EEKRREEKRREEKRREGKRREKEEE----- 98 ++E+ R +A R Q++E++RR E++RRE + R ++ RE +RRE+EE+ Sbjct: 381 LREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEE 440 Query: 99 -----KEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140 KEEEE EEE+ E E+E + L +R E +++L+ Sbjct: 441 LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487 Score = 47.0 bits (110), Expect = 5e-06 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 16/103 (15%) Query: 52 TLRHSMAGTSARKSQRREEKRREEKRREEKRRE----------------EKRREGKRREK 95 TLR +R E RR++ +E++ RE E+++E +RR + Sbjct: 351 TLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE 410 Query: 96 EEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+++ E E ++E E+ E+EE+ R R+ E E +R Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453 Score = 42.7 bits (99), Expect = 1e-04 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KE LR ++ Q RE++ + + E+++ ++++ +RR EE++ E E Sbjct: 364 KERSEALRRQQL---LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR 420 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 ++E E+ E+EE R E EE+R Sbjct: 421 RQQEREQRRREQEEKRRLEELERRRKEEEERR 452 Score = 40.4 bits (93), Expect = 5e-04 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 10/99 (10%) Query: 49 EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE------- 101 EP ++ + ++ R+ R ++ +E R E RR++ +E + RE+EE K + Sbjct: 339 EPSSIVNVPGESTLRRDFLRLQQENKE-RSEALRRQQLLQEQQLREQEEYKRQLLAERQK 397 Query: 102 --EEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+++E+ EE++ E E +R E EEKR Sbjct: 398 RIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436 Score = 34.3 bits (77), Expect = 0.036 Identities = 18/48 (37%), Positives = 26/48 (54%) Query: 73 REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 R++ + R + K + R+K EK+E E E EEEEEE E+E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE 337 Score = 32.3 bits (72), Expect = 0.14 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Query: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 R++ + R + K ++ R+ KR EK+E + E EEEEEE E+E E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRK-KRGEKDETEYEYSGSEEEEEEVPEQEGE 339 Score = 30.0 bits (66), Expect = 0.67 Identities = 18/50 (36%), Positives = 24/50 (48%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 + Q E + R + + R +KR E E E EEEEEE E+E E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339 Score = 28.1 bits (61), Expect = 2.6 Identities = 17/56 (30%), Positives = 26/56 (46%) Query: 53 LRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108 L+H + Q R + + R +KR E+ E + EEE+EE E+E E Sbjct: 284 LKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339 >gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens] Length = 1320 Score = 60.1 bits (144), Expect = 6e-10 Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 12/107 (11%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRR--EEKRREEKRREEKRREGKRREKEEE----- 98 ++E+ R +A R Q++E++RR E++RRE + R ++ RE +RRE+EE+ Sbjct: 381 LREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEE 440 Query: 99 -----KEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140 KEEEE EEE+ E E+E + L +R E +++L+ Sbjct: 441 LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487 Score = 47.0 bits (110), Expect = 5e-06 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 16/103 (15%) Query: 52 TLRHSMAGTSARKSQRREEKRREEKRREEKRRE----------------EKRREGKRREK 95 TLR +R E RR++ +E++ RE E+++E +RR + Sbjct: 351 TLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE 410 Query: 96 EEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+++ E E ++E E+ E+EE+ R R+ E E +R Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453 Score = 42.7 bits (99), Expect = 1e-04 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 KE LR ++ Q RE++ + + E+++ ++++ +RR EE++ E E Sbjct: 364 KERSEALRRQQL---LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR 420 Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 ++E E+ E+EE R E EE+R Sbjct: 421 RQQEREQRRREQEEKRRLEELERRRKEEEERR 452 Score = 40.4 bits (93), Expect = 5e-04 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 10/99 (10%) Query: 49 EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE------- 101 EP ++ + ++ R+ R ++ +E R E RR++ +E + RE+EE K + Sbjct: 339 EPSSIVNVPGESTLRRDFLRLQQENKE-RSEALRRQQLLQEQQLREQEEYKRQLLAERQK 397 Query: 102 --EEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+++E+ EE++ E E +R E EEKR Sbjct: 398 RIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436 Score = 34.3 bits (77), Expect = 0.036 Identities = 18/48 (37%), Positives = 26/48 (54%) Query: 73 REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 R++ + R + K + R+K EK+E E E EEEEEE E+E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE 337 Score = 33.5 bits (75), Expect = 0.061 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 63 RKSQRREEKRR--EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 R+ + EE+RR EEKRR E+ +E RR+ + ++ E +++ +E+ E E E Sbjct: 443 RRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREME 502 Query: 121 VSFSLATRERETETEEKRLIS 141 +R+ + E+ L+S Sbjct: 503 EHRQAERLQRQLQQEQAYLLS 523 Score = 32.3 bits (72), Expect = 0.14 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Query: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 R++ + R + K ++ R+ KR EK+E + E EEEEEE E+E E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRK-KRGEKDETEYEYSGSEEEEEEVPEQEGE 339 Score = 30.0 bits (66), Expect = 0.67 Identities = 18/50 (36%), Positives = 24/50 (48%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 + Q E + R + + R +KR E E E EEEEEE E+E E Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339 Score = 28.1 bits (61), Expect = 2.6 Identities = 17/56 (30%), Positives = 26/56 (46%) Query: 53 LRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108 L+H + Q R + + R +KR E+ E + EEE+EE E+E E Sbjct: 284 LKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 60.1 bits (144), Expect = 6e-10 Identities = 45/144 (31%), Positives = 65/144 (45%), Gaps = 20/144 (13%) Query: 6 HSRGFSSASSPENDRILL---------STFPYPHSKRENLAGLTNSTSSVKEEPPTLRHS 56 H + +S PE DR S+F H +R+ N + P +RH Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRR---DNRERDQRPSSP-IRHQ 648 Query: 57 MAGTSARKSQRREEKR--REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114 + +RREE+R R + RR+E+ RE R + RE+E E+E E + E E+E E E Sbjct: 649 GRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELE 708 Query: 115 EEEEEEVSFSLATRERETETEEKR 138 E E RERE E + +R Sbjct: 709 RERARE-----REREREKERDRER 727 Score = 60.1 bits (144), Expect = 6e-10 Identities = 28/77 (36%), Positives = 43/77 (55%) Query: 62 ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121 AR+ +R EK R+ +R ++ + +R + R++E+E+E E EE E E E E E E E Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERE 771 Query: 122 SFSLATRERETETEEKR 138 RER+ E E +R Sbjct: 772 RERERARERDKERERQR 788 Score = 57.4 bits (137), Expect = 4e-09 Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 8/84 (9%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE--------EEEEEEEEE 114 R +R E+ RE R EK RE +R + RE+E EKE + E E E E E + Sbjct: 685 RDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERD 744 Query: 115 EEEEEEVSFSLATRERETETEEKR 138 E+E E RERE E E +R Sbjct: 745 REKEREREREERERERERERERER 768 Score = 57.4 bits (137), Expect = 4e-09 Identities = 32/80 (40%), Positives = 45/80 (56%), Gaps = 4/80 (5%) Query: 63 RKSQRREEKRRE---EKRREEKRREEKRREGKR-REKEEEKEEEEEEEEEEEEEEEEEEE 118 R+ R EK RE E+ RE +R EK R+ +R R+++ ++E E E E + E+E E E E Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754 Query: 119 EEVSFSLATRERETETEEKR 138 E RERE E E +R Sbjct: 755 ERERERERERERERERERER 774 Score = 55.8 bits (133), Expect = 1e-08 Identities = 32/79 (40%), Positives = 41/79 (51%), Gaps = 3/79 (3%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE---EEEEEEEEEEEEE 119 R RR+E+ RE R E+ RE +R + R++E EKE E E E E E E E+E + E Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726 Query: 120 EVSFSLATRERETETEEKR 138 RERE E E R Sbjct: 727 RDRDRDHDRERERERERDR 745 Score = 55.1 bits (131), Expect = 2e-08 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 3/79 (3%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE---EEEEEEEEEEEEEEEEE 119 R+ +R E+ RE +R E+ RE +R + REKE E E E E E E E+E + E + + Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD 730 Query: 120 EVSFSLATRERETETEEKR 138 RERE + E++R Sbjct: 731 RDHDRERERERERDREKER 749 Score = 55.1 bits (131), Expect = 2e-08 Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 7/74 (9%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 + + R+ R E+ RE R +E+ RE + RE+E E+E E E E E E E E ++E Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKE--- 783 Query: 124 SLATRERETETEEK 137 RER+ + E+K Sbjct: 784 ----RERQRDWEDK 793 Score = 52.8 bits (125), Expect = 1e-07 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 11/86 (12%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKR---REKEEEKEEEEEEE--------EEEEEE 112 + + R+ +R E+ RE R EK RE +R RE+E E+E+E + E E E E Sbjct: 681 RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740 Query: 113 EEEEEEEEVSFSLATRERETETEEKR 138 E + E+E RERE E E +R Sbjct: 741 RERDREKEREREREERERERERERER 766 Score = 51.6 bits (122), Expect = 2e-07 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R R E+ RE R +E+ RE + RE + RE+E E+E E E E E E ++E E + Sbjct: 731 RDHDRERERERERDREKEREREREERE-RERERERERERERERERERARERDKERERQRD 789 Query: 123 FSLATRERETETEEKRLI 140 + + R+ E++ I Sbjct: 790 WEDKDKGRDDRREKREEI 807 Score = 51.6 bits (122), Expect = 2e-07 Identities = 24/75 (32%), Positives = 40/75 (53%) Query: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 + + RE R +E+ RE + RE +R + RE+E E+E E E ++E E + + E++ Sbjct: 737 RERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKG 796 Query: 124 SLATRERETETEEKR 138 RE+ E E R Sbjct: 797 RDDRREKREEIREDR 811 Score = 38.9 bits (89), Expect = 0.001 Identities = 30/123 (24%), Positives = 51/123 (41%), Gaps = 21/123 (17%) Query: 13 ASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLR--------HSMAGTSARK 64 +SS ++ + P P KR T S S + P LR HS++ ++ Sbjct: 333 SSSSQSGSSIQRHSPSPRRKR------TPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQ 386 Query: 65 SQRREEKRREEKRREEKRR-------EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117 S R EK R + R +RRE R +++ EK+ EE E E+++ + Sbjct: 387 SPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDH 446 Query: 118 EEE 120 ++ Sbjct: 447 RDD 449 Score = 38.9 bits (89), Expect = 0.001 Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 15/111 (13%) Query: 40 TNSTSSVKEEPPTLR--HSMAGTSARKSQRREEKR------REEKRREEKRREEKRREGK 91 + S SS + P + R HS +G+ + + +E R RE +RR+ ++RE R K Sbjct: 1270 SRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK 1329 Query: 92 ----RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 R+++ +E E E E ++ + + E E +S S+ ER+ + + R Sbjct: 1330 DWPRNRDRDRLRERERERERDKRRDLDRERERLISDSV---ERDRDRDRDR 1377 Score = 37.4 bits (85), Expect = 0.004 Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 11/117 (9%) Query: 24 STFPYP-HSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKR-REEKRREEK 81 S PYP HS S+ K+ PP R M +R + R +RRE+ Sbjct: 370 SASPYPSHSL---------SSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDT 420 Query: 82 RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 R + R + R E+E E+++ + ++ E + + + R ++ + R Sbjct: 421 RGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR 477 Score = 36.2 bits (82), Expect = 0.009 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 17/107 (15%) Query: 7 SRGFSSA-SSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKS 65 SR SS SSPE+DR + HS+ +G +S ++E R R+ Sbjct: 1270 SRSHSSRRSSPESDRQV-------HSR----SGSFDSRDRLQE-----RDRYEHDRERER 1313 Query: 66 QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112 +RR+ ++RE R +K R + RE+E E+E ++ + + E E Sbjct: 1314 ERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERE 1360 Score = 35.0 bits (79), Expect = 0.021 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 3/62 (4%) Query: 64 KSQRREEKRREEKRREEKRREEKRRE---GKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 K++R++ +KR E+ R+E G+ REKE+ K +E E EEE E E + Sbjct: 90 KNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRD 149 Query: 121 VS 122 S Sbjct: 150 DS 151 Score = 33.1 bits (74), Expect = 0.079 Identities = 16/58 (27%), Positives = 29/58 (50%) Query: 66 QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 +R + KR++ +KR E+ R+E + E+E+ + +E E EEE V + Sbjct: 87 ERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEW 144 Score = 30.8 bits (68), Expect = 0.39 Identities = 13/36 (36%), Positives = 25/36 (69%) Query: 71 KRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 K+ +EK + + R EEK R+GK R ++ E++ E+ ++ Sbjct: 278 KKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDK 313 Score = 30.8 bits (68), Expect = 0.39 Identities = 12/41 (29%), Positives = 26/41 (63%) Query: 73 REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 R+ + +EE R+ E++ +R E++E KE+ +++ E+ E Sbjct: 885 RQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTE 925 Score = 30.4 bits (67), Expect = 0.52 Identities = 20/81 (24%), Positives = 31/81 (38%) Query: 59 GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118 G S R RR +R RE + + + + E +K EE +E Sbjct: 62 GPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRH 121 Query: 119 EEVSFSLATRERETETEEKRL 139 E T+ER E+EE+ + Sbjct: 122 REKEDIKITKERTPESEEENV 142 Score = 30.4 bits (67), Expect = 0.52 Identities = 26/116 (22%), Positives = 47/116 (40%), Gaps = 6/116 (5%) Query: 30 HSKRENLAGLTNSTSSVKEEPPTLR--HSMAGTSARKSQRREEKRR----EEKRREEKRR 83 H +R++ N S + P R HS + + EK R + +E + Sbjct: 817 HDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSL 876 Query: 84 EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 R+ + +E++ + E +E EE+E +E+VS RE+ E R+ Sbjct: 877 SPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRM 932 Score = 30.4 bits (67), Expect = 0.52 Identities = 19/99 (19%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Query: 40 TNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEK 99 + STSS +++ + HS +S ++ + R+ + ++ + RE+E Sbjct: 1260 SRSTSSDRQDSRS--HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRD 1317 Query: 100 EEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 + E + + +++ + + L RERE E +++R Sbjct: 1318 TRQREWDRDADKDWPRNRDRD---RLRERERERERDKRR 1353 Score = 30.0 bits (66), Expect = 0.67 Identities = 17/68 (25%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Query: 65 SQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFS 124 ++ R+ + +EE R+ E R+E RR ++ KE+ +++ E+ E E +++ Sbjct: 882 TEDRQGRWKEEDRKPE-RKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGH 940 Query: 125 LATRERET 132 + +RET Sbjct: 941 HQSEDRET 948 Score = 29.6 bits (65), Expect = 0.88 Identities = 20/102 (19%), Positives = 40/102 (39%), Gaps = 4/102 (3%) Query: 30 HSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRRE 89 H +RE+ G + +EE R S+ + R + + R+ + R + R RRE Sbjct: 414 HERREDTRGKRDREKDSREE----REYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRE 469 Query: 90 GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERE 131 + + E + + +E + + + R+RE Sbjct: 470 LRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDRE 511 Score = 29.6 bits (65), Expect = 0.88 Identities = 14/47 (29%), Positives = 21/47 (44%) Query: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114 R+ + R+ R+E+ EE R G+ +EE E E E E Sbjct: 508 RDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSE 554 Score = 29.6 bits (65), Expect = 0.88 Identities = 16/68 (23%), Positives = 34/68 (50%), Gaps = 5/68 (7%) Query: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE----- 114 T R+ + +EE R+ E++ +R EE+ + K ++++E+ E E ++ Sbjct: 882 TEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHH 941 Query: 115 EEEEEEVS 122 + E+ E S Sbjct: 942 QSEDRETS 949 Score = 26.6 bits (57), Expect = 7.4 Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV- 121 R ++ R+E R R +E + K R E E+E E E ++ + + + V Sbjct: 103 RNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVH 162 Query: 122 SFSLATRERETETEEKRL 139 SL + ++ + E +L Sbjct: 163 ELSLEMKRQKIQRELMKL 180 Score = 26.6 bits (57), Expect = 7.4 Identities = 24/113 (21%), Positives = 40/113 (35%), Gaps = 18/113 (15%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKR-----------REEKRREGKR--- 92 +EE R + + RE R +K RE +R R EKR E + Sbjct: 753 REERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRN 812 Query: 93 ----REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141 ++ + K+ E + + E S A + + E+ RL+S Sbjct: 813 PRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLS 865 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 59.7 bits (143), Expect = 8e-10 Identities = 34/115 (29%), Positives = 60/115 (52%), Gaps = 7/115 (6%) Query: 27 PYPHSKRENLAGLT---NSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRR 83 PYP +E++ + + + E R + K ++ +E++ EK R E+ R Sbjct: 255 PYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERER 314 Query: 84 EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 E+ RE +RRE+E E+E E E E+E+E E E E + + T+ER+ + + +R Sbjct: 315 -ERERERERREREREREREREREKEKERERERERDRDRD---RTKERDRDRDRER 365 Score = 57.8 bits (138), Expect = 3e-09 Identities = 27/84 (32%), Positives = 46/84 (54%) Query: 54 RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 R+ S KS+ RE +R E+ RE +R E+ RE +R + E + E E++++ + EE+ Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436 Query: 114 EEEEEEEVSFSLATRERETETEEK 137 EE+ E RE+E +E+ Sbjct: 437 EEDAYERRKLERKLREKEAAYQER 460 Score = 55.5 bits (132), Expect = 1e-08 Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 1/83 (1%) Query: 54 RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 R S +S+ + R E+ RE +R E+ RE + RE+E E+E E E E E++++ Sbjct: 373 RSSDRNKDRSRSREKSRDRERERERERERERERERE-REREREREREREREREREKDKKR 431 Query: 114 EEEEEEEVSFSLATRERETETEE 136 + EE+EE ++ ER+ +E Sbjct: 432 DREEDEEDAYERRKLERKLREKE 454 Score = 55.1 bits (131), Expect = 2e-08 Identities = 26/76 (34%), Positives = 38/76 (50%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R +R ++ ++ R EK R+ +R + RE+E E+E E E E E E E E E E E Sbjct: 369 RDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKD 428 Query: 123 FSLATRERETETEEKR 138 E E + E+R Sbjct: 429 KKRDREEDEEDAYERR 444 Score = 54.7 bits (130), Expect = 3e-08 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 7/76 (9%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R+ R ++ R R +++ R ++ + RE+E E+E E E E E E E E E E E Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERE-- 420 Query: 123 FSLATRERETETEEKR 138 RERE E ++KR Sbjct: 421 -----REREREKDKKR 431 Score = 54.3 bits (129), Expect = 3e-08 Identities = 28/81 (34%), Positives = 47/81 (58%), Gaps = 4/81 (4%) Query: 59 GTSARKSQRREEKRREEKRREEKRREEKRREGKR-REKEEEKEEEEEEEEEEEEEEEEEE 117 G ++ Q E++RRE +R E+ RE + RE +R RE+E EKE+E E E E + + + + Sbjct: 296 GKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTK 355 Query: 118 EEEVSFSLATRERETETEEKR 138 E + RER+ + + +R Sbjct: 356 ERDRD---RDRERDRDRDRER 373 Score = 51.6 bits (122), Expect = 2e-07 Identities = 23/76 (30%), Positives = 43/76 (56%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R+ +R E+ RE +R E+ RE +R + REK+++++ EE+EE+ E + E + E Sbjct: 395 REREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKE 454 Query: 123 FSLATRERETETEEKR 138 + R + E E++ Sbjct: 455 AAYQERLKNWEIRERK 470 Score = 50.4 bits (119), Expect = 5e-07 Identities = 25/89 (28%), Positives = 47/89 (52%), Gaps = 13/89 (14%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 R+ +R E+ RE +R E+ RE +R + ++K+ ++EE+EE+ E + E + E+E + Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456 Query: 123 FSLATR-------------ERETETEEKR 138 + + E+E E EE+R Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEER 485 Score = 50.1 bits (118), Expect = 6e-07 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 25/115 (21%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKR------------------- 87 +++P R S R ++ E +++RE++ EE R Sbjct: 507 RDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRME 566 Query: 88 REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLISP 142 +E +RR + + K+E E EEEEEE++E+EE+ EE E E E E+K + P Sbjct: 567 QEAERRRQPQIKQEPESEEEEEEKQEKEEKREE------PMEEEEEPEQKPCLKP 615 Score = 46.6 bits (109), Expect = 7e-06 Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 19/127 (14%) Query: 23 LSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKR 82 +S F H K E G K+E + + RE +RRE +R E+ Sbjct: 281 ISKFRDTHKKLEEEKG--------KKEKERQEIEKERRERERERERERERRERERERERE 332 Query: 83 REEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL-----------ATRERE 131 RE ++ + + RE+E +++ + +E + + + E + + + S +R+RE Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRE 392 Query: 132 TETEEKR 138 E E +R Sbjct: 393 RERERER 399 Score = 42.0 bits (97), Expect = 2e-04 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 21/87 (24%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKE----------EEKEEEEEEEEEEEEE 112 R+ +R ++K+R+ + EE E ++ E K REKE E +E ++ E E+E E Sbjct: 421 REREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480 Query: 113 EEEEEEEEVSFSLATRERETETEEKRL 139 EEE R RE E KRL Sbjct: 481 REEE-----------RRREMAKEAKRL 496 Score = 35.8 bits (81), Expect = 0.012 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 20/97 (20%) Query: 63 RKSQRREEKR--REEKRREEKRREEKR------------------REGKRREKEEEKEEE 102 RK R EK REE+RR E +E KR R +++ ++E+E Sbjct: 469 RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528 Query: 103 EEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 E +E + + E+EE EE LA + + E +R+ Sbjct: 529 MEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRM 565 Score = 33.5 bits (75), Expect = 0.061 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 17/92 (18%) Query: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE---------EEEEE 113 R+ R+ + +E +E + E R K RE E+E E EEE E E E+ Sbjct: 443 RRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED 502 Query: 114 EEEEEEEVSF--------SLATRERETETEEK 137 +++ ++ + L RE+E E +E+ Sbjct: 503 YDDDRDDPKYYRGSALQKRLRDREKEMEADER 534 Score = 27.7 bits (60), Expect = 3.3 Identities = 13/46 (28%), Positives = 22/46 (47%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 +++E R + EEK+ +E++REE EE+ E K Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610 >gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sapiens] Length = 1925 Score = 59.7 bits (143), Expect = 8e-10 Identities = 34/62 (54%), Positives = 39/62 (62%) Query: 76 KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135 K+ +E R E GK+ E EEEK EEEEEE EEEEEEEEE EEE E+E E + Sbjct: 1744 KQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERD 1803 Query: 136 EK 137 EK Sbjct: 1804 EK 1805 Score = 50.4 bits (119), Expect = 5e-07 Identities = 28/66 (42%), Positives = 44/66 (66%), Gaps = 2/66 (3%) Query: 73 REEKRREEKRREEKRREGKRREKEEEKEEEE--EEEEEEEEEEEEEEEEEVSFSLATRER 130 ++E+ EEK EE+ + E+EEE EEEE +EE EE+EEE +E+EE+VS++ Sbjct: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818 Query: 131 ETETEE 136 + E++E Sbjct: 1819 QPESQE 1824 Score = 48.9 bits (115), Expect = 1e-06 Identities = 28/64 (43%), Positives = 38/64 (59%) Query: 75 EKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETET 134 E + ++ +E++ K+EE EEE+ EEEEEE EEEEEEEEE +E E Sbjct: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798 Query: 135 EEKR 138 EE+R Sbjct: 1799 EEER 1802 Score = 43.9 bits (102), Expect = 5e-05 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%) Query: 17 ENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEK 76 +N L+ P P S E+ G KE+ P G ++ E+ EE+ Sbjct: 1722 KNSLYLMPILPVPSSSWEDGKG-----KQPKEDRP---EHYPGLGKKEEGEEEKGEEEEE 1773 Query: 77 RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEE 111 EE+ EE+ E + KEE +E+EEE +E+EE+ Sbjct: 1774 ELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808 Score = 35.0 bits (79), Expect = 0.021 Identities = 19/51 (37%), Positives = 29/51 (56%) Query: 89 EGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 +GK ++ +E++ E ++EE EEE+ EEE E E ETEE+ L Sbjct: 1740 DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEEL 1790 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 59.3 bits (142), Expect = 1e-09 Identities = 39/122 (31%), Positives = 59/122 (48%), Gaps = 16/122 (13%) Query: 29 PHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREE--- 85 P K + S EE +L + + S+ EE+ EE+R EE+ REE Sbjct: 2209 PKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEE 2268 Query: 86 -------------KRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERET 132 K E K+++K+E+K+EE +E+EE EE+EE EE + SL+ E E Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328 Query: 133 ET 134 E+ Sbjct: 2329 ES 2330 Score = 58.5 bits (140), Expect = 2e-09 Identities = 35/89 (39%), Positives = 54/89 (60%), Gaps = 7/89 (7%) Query: 60 TSARKSQRREEKRREE---KRREEKRREEKRREGKRREKEEE----KEEEEEEEEEEEEE 112 +S + +R EE+ REE + EE+R+EE+ E K+ EKEEE K++E+++EE +E+E Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303 Query: 113 EEEEEEEEVSFSLATRERETETEEKRLIS 141 E EE+EE+ T E EE+ S Sbjct: 2304 EVFEEKEEIMSEEETESLSDEEEEEESCS 2332 Score = 57.8 bits (138), Expect = 3e-09 Identities = 42/120 (35%), Positives = 63/120 (52%), Gaps = 16/120 (13%) Query: 34 ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93 E+L S+ E R + + EE+R+EE+ EEK+ E++ E K++ Sbjct: 2231 ESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK 2290 Query: 94 EKEEEKEEEEEEEEEEEEEEE------------EEEEEEVSFSL---ATRERETETEEKR 138 +KE++KEE +E+EE EE+EE EEEEEE S SL RE+E +EK+ Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE-SCSLEEEVDREKEILKKEKQ 2349 Score = 52.8 bits (125), Expect = 1e-07 Identities = 32/77 (41%), Positives = 44/77 (57%), Gaps = 3/77 (3%) Query: 65 SQRREEKRREEKRREEKRR---EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121 S + +E EE EE E +++E E+EEE+EEEEE EEEE EEEEE +EE Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273 Query: 122 SFSLATRERETETEEKR 138 E+E E ++K+ Sbjct: 2274 EGEEKQVEKEEEEKKKK 2290 Score = 51.2 bits (121), Expect = 3e-07 Identities = 33/87 (37%), Positives = 45/87 (51%), Gaps = 14/87 (16%) Query: 67 RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE--------------EEEEEEEE 112 +R ++R+E +R +K +E+ + E EE EE E EEEEE EE Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253 Query: 113 EEEEEEEEVSFSLATRERETETEEKRL 139 EEE EEEEV R+ E E EEK++ Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQV 2280 Score = 49.7 bits (117), Expect = 8e-07 Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRRE--EKRREEKRREEKRREGKRREKEEEKEEEE 103 V+EE + G + + EEK+++ EK++EE + +E+ E K EE+ E Sbjct: 2262 VREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL 2321 Query: 104 EEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138 +EEEEEE EEE + + +E++ + +E+R Sbjct: 2322 SDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQR 2356 Score = 40.0 bits (92), Expect = 7e-04 Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 3/92 (3%) Query: 34 ENLAGLTNSTSSVK-EEPPTLRHSMAGTSARKSQRREEKRR--EEKRREEKRREEKRREG 90 EN+ + K EE TL ++ K Q+ E++R +E+ + + ++ R Sbjct: 1526 ENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAE 1585 Query: 91 KRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 K+R +EE K +EEE+ +EE + +EE +++ Sbjct: 1586 KKRAQEERKLAQEEEKLAQEERQLAQEERKLA 1617 Score = 38.5 bits (88), Expect = 0.002 Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 9/117 (7%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91 K LA + N + EE P ++ +Q EE + + K E + EGK Sbjct: 1682 KGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGK 1741 Query: 92 RREKEEEKEEEEE-----EEEEEEEEEEEEEEEEVSF----SLATRERETETEEKRL 139 E++++ EEEE E+ EEE + +EEE+ LA + + EE+RL Sbjct: 1742 LVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERL 1798 Score = 36.6 bits (83), Expect = 0.007 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 7/72 (9%) Query: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLAT 127 RE + +E++ EE+R ++ + R ++ + E++ +EE + +EEE+ LA Sbjct: 1552 REGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK-------LAQ 1604 Query: 128 RERETETEEKRL 139 ER+ EE++L Sbjct: 1605 EERQLAQEERKL 1616 Score = 35.4 bits (80), Expect = 0.016 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 8/81 (9%) Query: 65 SQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEE-------EEEEEEEEEEEEEE 117 S++R E ++EK+ K+R+ + + KEE+ EEE E ++EEE E Sbjct: 2126 SEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185 Query: 118 EEEVSFSLATRERETETEEKR 138 EEEV L R R+ + E KR Sbjct: 2186 EEEVIPFLKRRWRKRK-EAKR 2205 Score = 35.0 bits (79), Expect = 0.021 Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 11/143 (7%) Query: 4 YGHSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVK----EEPPTLRHSMAG 59 +G +R A E ++ LL H E L+ K EE + +M Sbjct: 1471 HGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLS 1530 Query: 60 TSARKSQRREEKR---REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEE 116 + +++ Q ++E+ EE RE + +E++ E +R +EE K + E++ + Sbjct: 1531 SKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590 Query: 117 EEEEVSFSLATRERETETEEKRL 139 EE + LA E + EE++L Sbjct: 1591 EERK----LAQEEEKLAQEERQL 1609 Score = 32.3 bits (72), Expect = 0.14 Identities = 19/64 (29%), Positives = 39/64 (60%), Gaps = 3/64 (4%) Query: 60 TSARKSQRREEKRREEKRREEKRR--EEKRREGK-RREKEEEKEEEEEEEEEEEEEEEEE 116 T ++ ++EEK+ +K ++ R+ +++R+ GK +RE +E+ + EE EE EE+ Sbjct: 1382 TMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKV 1441 Query: 117 EEEE 120 ++E Sbjct: 1442 VKQE 1445 Score = 31.6 bits (70), Expect = 0.23 Identities = 21/98 (21%), Positives = 47/98 (47%), Gaps = 4/98 (4%) Query: 46 VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE- 104 V EE ++ + + R EK+R ++ R+ + EEK + +R+ +EE++ + Sbjct: 1561 VTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAY 1620 Query: 105 ---EEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139 +++ E + E + + +LA R + E ++L Sbjct: 1621 VKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKL 1658 Score = 31.6 bits (70), Expect = 0.23 Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 3/52 (5%) Query: 62 ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113 ARK ++ K R +EEK EE E K K E ++EEE EEEE Sbjct: 2140 ARKQRKLANKMRRMINKEEKMTEE---ESKLARKHSEVILDDEEEGGIEEEE 2188 Score = 30.8 bits (68), Expect = 0.39 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Query: 73 REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERET 132 +E ++EEK+ +K K+ K +KE + + + E +EE + EEV +AT E + Sbjct: 1385 KEISKKEEKKTFQK--SPKQGRKAVQKERKVGKIKREMTKEERDMSEEVE-EMATLEEKV 1441 Query: 133 ETEEKRLI 140 +E +L+ Sbjct: 1442 VKQEGKLV 1449 Score = 30.0 bits (66), Expect = 0.67 Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 7/79 (8%) Query: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEE-----EEEEEEEEEEEEEE-EEEV 121 +EE++ + + EE +E K+ + EE K+ E + +E++ ++EEE EEEV Sbjct: 1491 QEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEV 1550 Query: 122 SFSLATRERETETEEKRLI 140 S +E++ TEE+R I Sbjct: 1551 SREGEEKEQQV-TEEQRHI 1568 Score = 30.0 bits (66), Expect = 0.67 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 16/98 (16%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE---------- 96 KEE + K ++++EK++EE + +E+ EEK E E Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329 Query: 97 ----EEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRER 130 EE+ + E+E ++E++ + +E+ SL RER Sbjct: 2330 SCSLEEEVDREKEILKKEKQFKLQEQRRK--SLRGRER 2365 Score = 29.6 bits (65), Expect = 0.88 Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 28/124 (22%) Query: 39 LTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKR---REEKRREEKR------------- 82 +T ++EE R A K + +EE++ EEK +E+R Sbjct: 1561 VTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAY 1620 Query: 83 -------REEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135 RE + EGK +KEE + E+ +E E+ ++ ++ LA + + E Sbjct: 1621 VKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKK-----LAKKWEKVARE 1675 Query: 136 EKRL 139 E++L Sbjct: 1676 EEKL 1679 Score = 29.3 bits (64), Expect = 1.1 Identities = 26/92 (28%), Positives = 49/92 (53%), Gaps = 13/92 (14%) Query: 62 ARKSQRREEKRREEKRREEK--RREEK--RREGKRRE-------KEEEKEEEEEEEEEEE 110 ++++++ +KR++ ++ EK R EEK ++ GK E K EE + E+ + +E Sbjct: 1652 SQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQE 1711 Query: 111 EEEEEEEEEEV--SFSLATRERETETEEKRLI 140 +E +E EE L+ +E E EE +L+ Sbjct: 1712 KELAQELEELEWDMEELSWKEEELNQEEGKLV 1743 Score = 29.3 bits (64), Expect = 1.1 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 18/86 (20%) Query: 65 SQRREEKRREE-KRREEKRR--EEKRREGKRREKEEEKE----EEEE---EEEEEEEEEE 114 S + EE +EE K EEK++ EE+ +REK E+E +EEE +E+E+ + + Sbjct: 1729 SWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK 1788 Query: 115 E---EEEEEVSFSLATRERETETEEK 137 E EEEE + R+RE E+K Sbjct: 1789 EKMPEEEERLG-----RKREQLIEKK 1809 Score = 27.3 bits (59), Expect = 4.4 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 9/118 (7%) Query: 32 KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEK----RREEKRREEKR 87 KR+ LA + +E+ +A +Q+ EE + E+ + +E +E + Sbjct: 1661 KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEE 1720 Query: 88 REGKRRE---KEEEKEEEEEE--EEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140 E E KEEE +EE + EE+++ EEEE L+ E + EE+ LI Sbjct: 1721 LEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLI 1778 Score = 26.9 bits (58), Expect = 5.7 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Query: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRR----EEKRREEKRREGKRREKEEEKEEE 102 +EE + K + EE +EK + +EK EE+ R G++RE+ EK+ + Sbjct: 1752 EEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMK 1811 Query: 103 EEEEEEEEEEEEEE 116 ++ E EE Sbjct: 1812 LAQKRERWINSMEE 1825 Score = 26.2 bits (56), Expect = 9.7 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 45 SVKEEPPTLRHS-MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE 101 S KEE T + S G A + +R+ K + E +EE+ E+ E E++ K+E Sbjct: 1388 SKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQE 1445 Score = 26.2 bits (56), Expect = 9.7 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 2/76 (2%) Query: 45 SVKEEPPTLRHSMAGTSARKSQRREEKR--REEKRREEKRREEKRREGKRREKEEEKEEE 102 S KEE +K EE + EK EE+ + + E +EKE+ + + Sbjct: 1729 SWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK 1788 Query: 103 EEEEEEEEEEEEEEEE 118 E+ EEEE + E+ Sbjct: 1789 EKMPEEEERLGRKREQ 1804 Score = 26.2 bits (56), Expect = 9.7 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 76 KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135 ++R E ++EK+ K+R K K +EE+ EEE + + S + E E E Sbjct: 2127 EKRSELTKDEKKLARKQR-KLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185 Query: 136 EKRLI 140 E+ +I Sbjct: 2186 EEEVI 2190 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.296 0.117 0.292 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,083,536 Number of Sequences: 37866 Number of extensions: 516475 Number of successful extensions: 94723 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 2718 Number of HSP's successfully gapped in prelim test: 444 Number of HSP's that attempted gapping in prelim test: 6502 Number of HSP's gapped (non-prelim): 31356 length of query: 142 length of database: 18,247,518 effective HSP length: 92 effective length of query: 50 effective length of database: 14,763,846 effective search space: 738192300 effective search space used: 738192300 T: 11 A: 40 X1: 17 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 44 (21.9 bits) S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.