Guide to the Human Genome
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Search of human proteins with 239745093

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
         (142 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ...   279   5e-76
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    79   2e-15
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]     71   3e-13
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]      71   3e-13
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    70   6e-13
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    70   6e-13
gi|17975763 myelin transcription factor 1 [Homo sapiens]               69   2e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            68   3e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    67   5e-12
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    64   4e-11
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    64   4e-11
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        63   7e-11
gi|21735569 claspin [Homo sapiens]                                     63   9e-11
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    62   1e-10
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom...    62   2e-10
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom...    62   2e-10
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          61   3e-10
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           61   3e-10
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           61   3e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            61   4e-10
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            61   4e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    60   5e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    60   5e-10
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    60   6e-10
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    60   6e-10
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    60   6e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        60   6e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                60   8e-10
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa...    60   8e-10
gi|221219020 NYD-SP11 protein [Homo sapiens]                           59   1e-09

>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
           sapiens]
          Length = 142

 Score =  279 bits (714), Expect = 5e-76
 Identities = 142/142 (100%), Positives = 142/142 (100%)

Query: 1   MTAYGHSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGT 60
           MTAYGHSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGT
Sbjct: 1   MTAYGHSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGT 60

Query: 61  SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE
Sbjct: 61  SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120

Query: 121 VSFSLATRERETETEEKRLISP 142
           VSFSLATRERETETEEKRLISP
Sbjct: 121 VSFSLATRERETETEEKRLISP 142


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 78.6 bits (192), Expect = 2e-15
 Identities = 37/76 (48%), Positives = 56/76 (73%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           RK + +++K +E ++R+EK  EEK+R+ KR++K+EE+E EEEEEEEEEE+EEEE+EE   
Sbjct: 37  RKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRR 96

Query: 123 FSLATRERETETEEKR 138
                + R  E EE++
Sbjct: 97  RKKKKKRRRKEEEEEK 112



 Score = 73.9 bits (180), Expect = 4e-14
 Identities = 37/81 (45%), Positives = 56/81 (69%), Gaps = 5/81 (6%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           RK +R+E++++++ +  EKR+E++  E KR+ K ++K+EEEE EEEEEEEEEE+EEEE  
Sbjct: 33  RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92

Query: 123 -----FSLATRERETETEEKR 138
                     R R+ E EEK+
Sbjct: 93  EGRRRKKKKKRRRKEEEEEKK 113



 Score = 69.7 bits (169), Expect = 8e-13
 Identities = 34/76 (44%), Positives = 53/76 (69%), Gaps = 1/76 (1%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           +K + +E ++R+EK  EEK+R+ KR++ K+ E+E E+EEEEEEEE+EEEE+EE    +  
Sbjct: 42  KKKKTKETEKRKEKEEEEKKRKRKRKK-KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100

Query: 123 FSLATRERETETEEKR 138
                +E E E ++KR
Sbjct: 101 KKRRRKEEEEEKKKKR 116



 Score = 68.2 bits (165), Expect = 2e-12
 Identities = 36/90 (40%), Positives = 55/90 (61%), Gaps = 11/90 (12%)

Query: 60  TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEE-----------EEEEE 108
           T   + +  +E +R+EKR+E+++ +EK+++ K  EK +EKEEEE           EEEE 
Sbjct: 16  TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEER 75

Query: 109 EEEEEEEEEEEEVSFSLATRERETETEEKR 138
           EEEEEEEEEE+E       R R+ + + +R
Sbjct: 76  EEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105



 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 27/74 (36%), Positives = 47/74 (63%), Gaps = 1/74 (1%)

Query: 60  TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
           T  RK +  EEK+R+ KR++ K+ EE+R E +  E+EE++EEE+EE    +++++   +E
Sbjct: 49  TEKRKEKEEEEKKRKRKRKK-KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107

Query: 120 EVSFSLATRERETE 133
           E       R R+T+
Sbjct: 108 EEEEKKKKRRRKTK 121



 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 19/57 (33%), Positives = 42/57 (73%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
           +K +  EE+  EE+  EE++ EE++ EG+RR+K++++  +EEEEE++++   + +++
Sbjct: 67  KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 21/58 (36%), Positives = 41/58 (70%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           RK ++ EE+R EE+  EE+ +EE+ +E  RR K+++K   +EEEEE++++   + +++
Sbjct: 66  RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 47.0 bits (110), Expect = 5e-06
 Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 1/70 (1%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KEE    R         + +R EE+  EE+ +EE+ +EE RR  K+++K   KEEEEE++
Sbjct: 55  KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR-KKKKKRRRKEEEEEKK 113

Query: 107 EEEEEEEEEE 116
           ++   + +++
Sbjct: 114 KKRRRKTKKK 123



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 17/75 (22%), Positives = 41/75 (54%)

Query: 40  TNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEK 99
           T      +EE    +         + +  EE+  EE++ EE++ E +RR+ K++ + +E+
Sbjct: 49  TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108

Query: 100 EEEEEEEEEEEEEEE 114
           EEE++++   + +++
Sbjct: 109 EEEKKKKRRRKTKKK 123


>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
          Length = 1113

 Score = 71.2 bits (173), Expect = 3e-13
 Identities = 42/101 (41%), Positives = 57/101 (56%), Gaps = 16/101 (15%)

Query: 50  PPTLRHS---------MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKE 100
           PP L HS         M+G SA + Q  EE RRE +R  E+ RE +R   + REKE E+E
Sbjct: 203 PPELSHSSLAALHSERMSGLSAERLQMDEELRRERER--EREREREREADREREKERERE 260

Query: 101 EEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141
            E+E E+E+E E E+E E E+      R+RE    EK L++
Sbjct: 261 REKEREQEKEREREKERERELE-----RQREQRAREKELLA 296



 Score = 46.6 bits (109), Expect = 7e-06
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)

Query: 34  ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93
           E ++GL+     + EE    R         +   RE ++  E+ RE++R +EK RE   R
Sbjct: 217 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---R 273

Query: 94  EKEEEKEEEEEEEEEEEEEE 113
           EKE E+E E + E+   E+E
Sbjct: 274 EKERERELERQREQRAREKE 293



 Score = 32.0 bits (71), Expect = 0.18
 Identities = 13/30 (43%), Positives = 22/30 (73%)

Query: 92   RREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121
            R+    ++ + + EEEEEE++E+ E+EEEV
Sbjct: 985  RKGPPTQELDRDSEEEEEEDDEDGEDEEEV 1014



 Score = 31.6 bits (70), Expect = 0.23
 Identities = 13/29 (44%), Positives = 21/29 (72%)

Query: 87   RREGKRREKEEEKEEEEEEEEEEEEEEEE 115
            R+    +E + + EEEEEE++E+ E+EEE
Sbjct: 985  RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1013



 Score = 31.6 bits (70), Expect = 0.23
 Identities = 13/29 (44%), Positives = 21/29 (72%)

Query: 88   REGKRREKEEEKEEEEEEEEEEEEEEEEE 116
            R+G   ++ +   EEEEEE++E+ E+EEE
Sbjct: 985  RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1013



 Score = 30.8 bits (68), Expect = 0.39
 Identities = 16/59 (27%), Positives = 32/59 (54%)

Query: 82   RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
            R+    +E  R  +EEE+E++E+ E+EEE  + + +  E  F       E +  E++++
Sbjct: 985  RKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVL 1043



 Score = 28.9 bits (63), Expect = 1.5
 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 3/95 (3%)

Query: 47   KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
            ++EPPT R         +    EE+  +E   +E+   +++ +G     E  +E  EE+ 
Sbjct: 978  QQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQN 1037

Query: 107  EEEEEEEEE---EEEEEVSFSLATRERETETEEKR 138
             E +  + +    E    S SL   +      E R
Sbjct: 1038 LERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELR 1072



 Score = 26.2 bits (56), Expect = 9.7
 Identities = 11/43 (25%), Positives = 21/43 (48%)

Query: 78   REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
            +   R    +  G++      K    +E + + EEEEEE++E+
Sbjct: 965  QSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDED 1007


>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
          Length = 1217

 Score = 71.2 bits (173), Expect = 3e-13
 Identities = 42/101 (41%), Positives = 57/101 (56%), Gaps = 16/101 (15%)

Query: 50  PPTLRHS---------MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKE 100
           PP L HS         M+G SA + Q  EE RRE +R  E+ RE +R   + REKE E+E
Sbjct: 307 PPELSHSSLAALHSERMSGLSAERLQMDEELRRERER--EREREREREADREREKERERE 364

Query: 101 EEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141
            E+E E+E+E E E+E E E+      R+RE    EK L++
Sbjct: 365 REKEREQEKEREREKERERELE-----RQREQRAREKELLA 400



 Score = 46.6 bits (109), Expect = 7e-06
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)

Query: 34  ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93
           E ++GL+     + EE    R         +   RE ++  E+ RE++R +EK RE   R
Sbjct: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---R 377

Query: 94  EKEEEKEEEEEEEEEEEEEE 113
           EKE E+E E + E+   E+E
Sbjct: 378 EKERERELERQREQRAREKE 397



 Score = 32.0 bits (71), Expect = 0.18
 Identities = 13/30 (43%), Positives = 22/30 (73%)

Query: 92   RREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121
            R+    ++ + + EEEEEE++E+ E+EEEV
Sbjct: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEEV 1118



 Score = 31.6 bits (70), Expect = 0.23
 Identities = 13/29 (44%), Positives = 21/29 (72%)

Query: 87   RREGKRREKEEEKEEEEEEEEEEEEEEEE 115
            R+    +E + + EEEEEE++E+ E+EEE
Sbjct: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1117



 Score = 31.6 bits (70), Expect = 0.23
 Identities = 13/29 (44%), Positives = 21/29 (72%)

Query: 88   REGKRREKEEEKEEEEEEEEEEEEEEEEE 116
            R+G   ++ +   EEEEEE++E+ E+EEE
Sbjct: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1117



 Score = 30.8 bits (68), Expect = 0.39
 Identities = 16/59 (27%), Positives = 32/59 (54%)

Query: 82   RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
            R+    +E  R  +EEE+E++E+ E+EEE  + + +  E  F       E +  E++++
Sbjct: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVL 1147



 Score = 28.9 bits (63), Expect = 1.5
 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 3/95 (3%)

Query: 47   KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
            ++EPPT R         +    EE+  +E   +E+   +++ +G     E  +E  EE+ 
Sbjct: 1082 QQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQN 1141

Query: 107  EEEEEEEEE---EEEEEVSFSLATRERETETEEKR 138
             E +  + +    E    S SL   +      E R
Sbjct: 1142 LERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELR 1176



 Score = 26.2 bits (56), Expect = 9.7
 Identities = 11/43 (25%), Positives = 21/43 (48%)

Query: 78   REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
            +   R    +  G++      K    +E + + EEEEEE++E+
Sbjct: 1069 QSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDED 1111


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 70.1 bits (170), Expect = 6e-13
 Identities = 36/93 (38%), Positives = 60/93 (64%), Gaps = 1/93 (1%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           K+E    R   A  + R +++RE++RRE++RRE++RRE++RRE +RRE+E +  E+E   
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 726

Query: 107 EEEE-EEEEEEEEEEVSFSLATRERETETEEKR 138
           E+E  + E E +E E +  L   + + E EEK+
Sbjct: 727 EQERLQAERELQEREKALRLQKEQLQRELEEKK 759



 Score = 58.9 bits (141), Expect = 1e-09
 Identities = 33/87 (37%), Positives = 57/87 (65%), Gaps = 12/87 (13%)

Query: 63  RKSQRREEKRREEKRREEKRRE--------EKRREGKRREKEEEKEEEEE----EEEEEE 110
           R+ +RRE++RRE++RRE++RRE        E+RRE +R + E E +E E+    ++E+ +
Sbjct: 693 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 752

Query: 111 EEEEEEEEEEVSFSLATRERETETEEK 137
            E EE++++E    LA R+ + E E+K
Sbjct: 753 RELEEKKKKEEQQRLAERQLQEEQEKK 779



 Score = 54.3 bits (129), Expect = 3e-08
 Identities = 27/94 (28%), Positives = 50/94 (53%)

Query: 46  VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE 105
           +++E    RH       ++ ++   ++  E +R  ++RE++RRE +RRE+E  ++E  E+
Sbjct: 651 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 710

Query: 106 EEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
           E  E+E +  E+E          ERE +  EK L
Sbjct: 711 ERREQERQLAEQERRREQERLQAERELQEREKAL 744



 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 1/89 (1%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           +EE   LR        R+ Q   +K++EE++   ++  E +R  ++RE+E  ++E  E+E
Sbjct: 642 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 701

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETE 135
             E+E  E+E  E+    LA +ER  E E
Sbjct: 702 RREQERREQERREQ-ERQLAEQERRREQE 729



 Score = 46.2 bits (108), Expect = 9e-06
 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 13/119 (10%)

Query: 34  ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93
           +  A +   T   KEE      +    +A+K +  E +R++E+     R  ++  E +R 
Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 660

Query: 94  EKEEEKEEEEEEE-------------EEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
           ++  +K++EEE+E             + E+E  E+E  E+       RE+E   +E++L
Sbjct: 661 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 719



 Score = 43.1 bits (100), Expect = 8e-05
 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 14/90 (15%)

Query: 63  RKSQRREEKRR--EEK-----RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE-- 113
           R  Q +EEK++  E+K      + EK +EE+  E K ++K   K+ EE E   ++EEE  
Sbjct: 587 RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 646

Query: 114 -----EEEEEEEVSFSLATRERETETEEKR 138
                ++EEEE     L  +++E E E  R
Sbjct: 647 RLRWLQQEEEERRHQELLQKKKEEEQERLR 676



 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 40/103 (38%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKR------------------------------ 92
           R+ +RRE++RRE++RRE++RRE++RRE +R                              
Sbjct: 688 REQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 747

Query: 93  ----------REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125
                     ++K+EE++   E + +EE+E++ +E    S +L
Sbjct: 748 KEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 790



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 14/129 (10%)

Query: 23  LSTFPYPHSKRENLAGLTNSTSSV-----KEEPPTLRHSMAGTSARKSQRREEKRREEKR 77
           L TF +   + + L   T++  SV     K   P           ++ QR E  RR+E+ 
Sbjct: 492 LRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEA 551

Query: 78  REEKRREEKRREGKRREKEEEKEEEEE------EEEEEEEEEEEEEEEEVSFSLATRERE 131
             E+ R +K  E KRR  EE K + EE      +  E  E+ +EE+++++    A  + +
Sbjct: 552 --EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 609

Query: 132 TE-TEEKRL 139
           TE  +E+RL
Sbjct: 610 TEKAKEERL 618



 Score = 40.8 bits (94), Expect = 4e-04
 Identities = 20/60 (33%), Positives = 41/60 (68%), Gaps = 2/60 (3%)

Query: 62  ARKSQRREEKRREEKRREEKRREEKR--REGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
           A + +RRE++R + +R  ++R +  R  +E  +RE EE+K++EE++   E + +EE+E++
Sbjct: 720 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 779



 Score = 39.7 bits (91), Expect = 8e-04
 Identities = 23/92 (25%), Positives = 46/92 (50%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KEE   LR        R+     + +REE+ R+  +  E+  + K  +K++ +++  + +
Sbjct: 548 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 607

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           E+ E+ +EE   EE +   A  ++  E E +R
Sbjct: 608 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 639


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 70.1 bits (170), Expect = 6e-13
 Identities = 36/93 (38%), Positives = 60/93 (64%), Gaps = 1/93 (1%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           K+E    R   A  + R +++RE++RRE++RRE++RRE++RRE +RRE+E +  E+E   
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 722

Query: 107 EEEE-EEEEEEEEEEVSFSLATRERETETEEKR 138
           E+E  + E E +E E +  L   + + E EEK+
Sbjct: 723 EQERLQAERELQEREKALRLQKEQLQRELEEKK 755



 Score = 58.9 bits (141), Expect = 1e-09
 Identities = 33/87 (37%), Positives = 57/87 (65%), Gaps = 12/87 (13%)

Query: 63  RKSQRREEKRREEKRREEKRRE--------EKRREGKRREKEEEKEEEEE----EEEEEE 110
           R+ +RRE++RRE++RRE++RRE        E+RRE +R + E E +E E+    ++E+ +
Sbjct: 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 748

Query: 111 EEEEEEEEEEVSFSLATRERETETEEK 137
            E EE++++E    LA R+ + E E+K
Sbjct: 749 RELEEKKKKEEQQRLAERQLQEEQEKK 775



 Score = 54.3 bits (129), Expect = 3e-08
 Identities = 27/94 (28%), Positives = 50/94 (53%)

Query: 46  VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE 105
           +++E    RH       ++ ++   ++  E +R  ++RE++RRE +RRE+E  ++E  E+
Sbjct: 647 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 706

Query: 106 EEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
           E  E+E +  E+E          ERE +  EK L
Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREKAL 740



 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 1/89 (1%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           +EE   LR        R+ Q   +K++EE++   ++  E +R  ++RE+E  ++E  E+E
Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETE 135
             E+E  E+E  E+    LA +ER  E E
Sbjct: 698 RREQERREQERREQ-ERQLAEQERRREQE 725



 Score = 46.2 bits (108), Expect = 9e-06
 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 13/119 (10%)

Query: 34  ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93
           +  A +   T   KEE      +    +A+K +  E +R++E+     R  ++  E +R 
Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656

Query: 94  EKEEEKEEEEEEE-------------EEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
           ++  +K++EEE+E             + E+E  E+E  E+       RE+E   +E++L
Sbjct: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715



 Score = 43.1 bits (100), Expect = 8e-05
 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 14/90 (15%)

Query: 63  RKSQRREEKRR--EEK-----RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE-- 113
           R  Q +EEK++  E+K      + EK +EE+  E K ++K   K+ EE E   ++EEE  
Sbjct: 583 RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 642

Query: 114 -----EEEEEEEVSFSLATRERETETEEKR 138
                ++EEEE     L  +++E E E  R
Sbjct: 643 RLRWLQQEEEERRHQELLQKKKEEEQERLR 672



 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 40/103 (38%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKR------------------------------ 92
           R+ +RRE++RRE++RRE++RRE++RRE +R                              
Sbjct: 684 REQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 743

Query: 93  ----------REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125
                     ++K+EE++   E + +EE+E++ +E    S +L
Sbjct: 744 KEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786



 Score = 40.8 bits (94), Expect = 4e-04
 Identities = 20/60 (33%), Positives = 41/60 (68%), Gaps = 2/60 (3%)

Query: 62  ARKSQRREEKRREEKRREEKRREEKR--REGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
           A + +RRE++R + +R  ++R +  R  +E  +RE EE+K++EE++   E + +EE+E++
Sbjct: 716 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775



 Score = 40.0 bits (92), Expect = 7e-04
 Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 9/84 (10%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE------EEEEEEEEEEEE 116
           ++ QR E  RR+E+   E+ R +K  E KRR  EE K + EE      +  E  E+ +EE
Sbjct: 533 KERQRLENLRRKEEA--EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590

Query: 117 EEEEVSFSLATRERETE-TEEKRL 139
           +++++    A  + +TE  +E+RL
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERL 614



 Score = 39.7 bits (91), Expect = 8e-04
 Identities = 23/92 (25%), Positives = 46/92 (50%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KEE   LR        R+     + +REE+ R+  +  E+  + K  +K++ +++  + +
Sbjct: 544 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           E+ E+ +EE   EE +   A  ++  E E +R
Sbjct: 604 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 635



 Score = 35.4 bits (80), Expect = 0.016
 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 8/88 (9%)

Query: 57  MAGTSARKS------QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEE 110
           M  TSA +S      +R    R + K +E +R E  RR  K   ++  +++ EE++    
Sbjct: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR--KEEAEQLRRQKVEEDKRRRL 563

Query: 111 EEEEEEEEEEVSFSLATRERETETEEKR 138
           EE + + EE +   L  RER  + +E++
Sbjct: 564 EEVKLKREERLRKVLQARERVEQMKEEK 591



 Score = 34.3 bits (77), Expect = 0.036
 Identities = 19/77 (24%), Positives = 41/77 (53%), Gaps = 2/77 (2%)

Query: 63  RKSQRREEKRREEKRREEKRR--EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           R+ +  E+ RR++   +++RR  E K +  +R  K  +  E  E+ +EE++++ E++  +
Sbjct: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 601

Query: 121 VSFSLATRERETETEEK 137
           +       + E   EEK
Sbjct: 602 IDEKTEKAKEERLAEEK 618


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 68.6 bits (166), Expect = 2e-12
 Identities = 36/88 (40%), Positives = 51/88 (57%)

Query: 51  PTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEE 110
           P      A   + K +       E++  EE+  EE+  E +  E+EEE+EEEEEEEEEEE
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296

Query: 111 EEEEEEEEEEVSFSLATRERETETEEKR 138
           EEEEEEEEEE +  +  +E  + T  ++
Sbjct: 297 EEEEEEEEEEAAPDVIFQEDTSHTSAQK 324



 Score = 67.8 bits (164), Expect = 3e-12
 Identities = 33/70 (47%), Positives = 47/70 (67%)

Query: 50  PPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE 109
           P +L  + +  S+++      +  +E+  EE+  EE+  E +  E+EEE+EEEEEEEEEE
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296

Query: 110 EEEEEEEEEE 119
           EEEEEEEEEE
Sbjct: 297 EEEEEEEEEE 306



 Score = 62.4 bits (150), Expect = 1e-10
 Identities = 34/82 (41%), Positives = 48/82 (58%)

Query: 61  SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           +  +SQ    +  E+   EE  +++     +  ++EEE+EEEEEEE+EEEEEEEEEEEEE
Sbjct: 228 TTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 287

Query: 121 VSFSLATRERETETEEKRLISP 142
                   E E E EE+   +P
Sbjct: 288 EEEEEEEEEEEEEEEEEEEAAP 309



 Score = 58.5 bits (140), Expect = 2e-09
 Identities = 33/89 (37%), Positives = 46/89 (51%)

Query: 49  EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108
           +P      +  T+ R      +   +    E  +++      +  E+EEE+EEEEEE+EE
Sbjct: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEE 276

Query: 109 EEEEEEEEEEEEVSFSLATRERETETEEK 137
           EEEEEEEEEEEE        E E E EE+
Sbjct: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305



 Score = 57.0 bits (136), Expect = 5e-09
 Identities = 29/73 (39%), Positives = 43/73 (58%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           + +  EE+  EE+  EE+  EE+  E +  E+EEE+EEEEEEEEEEE   +   +E+ S 
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319

Query: 124 SLATRERETETEE 136
           + A +  E    E
Sbjct: 320 TSAQKAPELRGPE 332



 Score = 49.7 bits (117), Expect = 8e-07
 Identities = 24/64 (37%), Positives = 36/64 (56%)

Query: 45  SVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE 104
           +  EE    +  ++     + +  EE+  EE   EE+  EE+  E +  E+EEE+EEEEE
Sbjct: 243 AASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302

Query: 105 EEEE 108
           EEEE
Sbjct: 303 EEEE 306



 Score = 49.7 bits (117), Expect = 8e-07
 Identities = 25/71 (35%), Positives = 39/71 (54%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           + +  EE+  E++  EE+  EE+  E +  E+EEE+EEEEEEEE   +   +E+    S 
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSA 322

Query: 124 SLATRERETET 134
             A   R  E+
Sbjct: 323 QKAPELRGPES 333



 Score = 40.0 bits (92), Expect = 7e-04
 Identities = 22/77 (28%), Positives = 37/77 (48%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           + +  EE   EE+  EE+  EE+  E +  E+EEE+EEEE   +   +E+      + + 
Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAP 326

Query: 124 SLATRERETETEEKRLI 140
            L   E  +   E  +I
Sbjct: 327 ELRGPESPSPKPEYSVI 343



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 7/110 (6%)

Query: 17  ENDRILLSTFPYPHSKRENLAGLTNSTSS---VKEEPPTLRHSMAGTSARKSQRREEKRR 73
           EN  + LS   + H KREN    ++S SS   VK    + RHS   TSA  S     +  
Sbjct: 665 ENGTLDLSM--HKHRKRENAFPSSSSCSSSPGVKSPDASQRHS--STSAPSSSMTSPQSS 720

Query: 74  EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           +  R++E  R     +  R  +EE +E E         E +++E  E +F
Sbjct: 721 QASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENF 770



 Score = 28.1 bits (61), Expect = 2.6
 Identities = 18/85 (21%), Positives = 39/85 (45%)

Query: 53  LRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112
           L+ +  G ++ + ++    + E+     +   E+ ++   +  E+   EE  +++     
Sbjct: 198 LQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSH 257

Query: 113 EEEEEEEEVSFSLATRERETETEEK 137
           EEE+EEEE        + E E EE+
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEE 282


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 67.8 bits (164), Expect = 3e-12
 Identities = 36/106 (33%), Positives = 59/106 (55%), Gaps = 11/106 (10%)

Query: 44  SSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEE 103
           S ++E    +     G   R+S+R++E+R  EKR+ E+ +E KR  GK+ +K E K+EE 
Sbjct: 36  SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95

Query: 104 E-----------EEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           E           E EE+E+ +++E++E    S   +ERE + E KR
Sbjct: 96  ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141



 Score = 66.2 bits (160), Expect = 8e-12
 Identities = 32/107 (29%), Positives = 67/107 (62%), Gaps = 3/107 (2%)

Query: 32  KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
           ++EN  G        KE+    R S  G   ++ +R+EE++REE++  E+++EE+ +E +
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEG---KERERKEERKREERKERERKKEEREKERE 159

Query: 92  RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           R+E+++ + ++  E+EEE +E+E +E ++   +   R++E E +E+R
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206



 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 37/109 (33%), Positives = 57/109 (52%), Gaps = 17/109 (15%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREE------------KRREEKRR-----E 89
           K E    R    G   +K +R++E+R  +KRR E            K++E+K R     E
Sbjct: 70  KREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE 129

Query: 90  GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           GK RE++EE++ EE +E E ++EE E+E E        R++  E EE+R
Sbjct: 130 GKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178



 Score = 58.5 bits (140), Expect = 2e-09
 Identities = 25/71 (35%), Positives = 49/71 (69%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           +K +R++   +EE+R+E++R+E K+RE  R+E+++E+E +E  E ++E +++EE ++E  
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQ 223

Query: 123 FSLATRERETE 133
               T  RE E
Sbjct: 224 KDRQTNWREKE 234



 Score = 56.2 bits (134), Expect = 9e-09
 Identities = 25/78 (32%), Positives = 52/78 (66%), Gaps = 3/78 (3%)

Query: 63  RKSQRREEKRREEKR---REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
           ++ +R+E K+RE K+   +EE+R+E++R+E K+RE+  ++ ++E E +E  E ++E +++
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215

Query: 120 EVSFSLATRERETETEEK 137
           E       ++R+T   EK
Sbjct: 216 EERKKERQKDRQTNWREK 233



 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 23/72 (31%), Positives = 50/72 (69%), Gaps = 1/72 (1%)

Query: 68  REEKRREEKRREEKRREEKRREGKR-REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126
           +EE+R+E++R+E K+RE  R+E K+ RE++E +E ++E +++EE ++E +++ + ++   
Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233

Query: 127 TRERETETEEKR 138
            R +    E K+
Sbjct: 234 ERGKRERKERKK 245



 Score = 54.7 bits (130), Expect = 3e-08
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 2/109 (1%)

Query: 32  KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKR--REEKRREEKRREEKRRE 89
           K +   G T+     +E     +        RK + RE++R  +E K+RE K+  EK  E
Sbjct: 118 KEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEE 177

Query: 90  GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            K +E++E K+ E   +E ++E E +E  E         ER+ E ++ R
Sbjct: 178 RKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226



 Score = 53.9 bits (128), Expect = 4e-08
 Identities = 28/87 (32%), Positives = 53/87 (60%), Gaps = 11/87 (12%)

Query: 63  RKSQRREEKRREEKRREEKRREEKR------REGKRREKEEEKEEEEEEE-----EEEEE 111
           RK +RRE++ +E + +E+++++EK+      +EGK RE++EE++ EE +E     EE E+
Sbjct: 97  RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156

Query: 112 EEEEEEEEEVSFSLATRERETETEEKR 138
           E E +E ++        + E   E++R
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKER 183



 Score = 53.9 bits (128), Expect = 4e-08
 Identities = 21/68 (30%), Positives = 46/68 (67%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           K + R+EK R+E+++ E+ R+E+++E +R+E+ E K+E +++EE ++E +++ +      
Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233

Query: 124 SLATRERE 131
               RER+
Sbjct: 234 ERGKRERK 241



 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 2/76 (2%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           RK    +E+ R+EK R+E+++ E+ R  K R+KE E++E  E ++E +++EE ++E +  
Sbjct: 168 RKQVGEKEEERKEKERKERKKRERNR--KERKKERERKERRERKKERKKKEERKKERQKD 225

Query: 123 FSLATRERETETEEKR 138
                RE+E    E++
Sbjct: 226 RQTNWREKERGKRERK 241



 Score = 50.8 bits (120), Expect = 4e-07
 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 4/78 (5%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE---EEEEEEEEEEE 120
           +S+ RE +R  E R+E K+  E  R+ +RRE+E+ K E E+E + E   +E++ E ++EE
Sbjct: 35  QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94

Query: 121 VSFSLATRERET-ETEEK 137
                  RE+E  E EEK
Sbjct: 95  RERKKRRREKENKEGEEK 112



 Score = 48.9 bits (115), Expect = 1e-06
 Identities = 20/69 (28%), Positives = 48/69 (69%), Gaps = 2/69 (2%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           RK + R+E+++ E+ R+E+++E +R+E  RRE+++E++++EE ++E +++ +    E+  
Sbjct: 178 RKEKERKERKKRERNRKERKKERERKE--RRERKKERKKKEERKKERQKDRQTNWREKER 235

Query: 123 FSLATRERE 131
                +ER+
Sbjct: 236 GKRERKERK 244



 Score = 44.3 bits (103), Expect = 3e-05
 Identities = 15/58 (25%), Positives = 40/58 (68%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           ++ + R+E+++E +R+E + R+++R++ + R+KE +K+ +    E+E  + E +E ++
Sbjct: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245



 Score = 40.0 bits (92), Expect = 7e-04
 Identities = 17/67 (25%), Positives = 37/67 (55%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KE+    R         + + RE K R E+++E K++EE+++E ++  +   +E+E  + 
Sbjct: 179 KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238

Query: 107 EEEEEEE 113
           E +E ++
Sbjct: 239 ERKERKK 245


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 67.0 bits (162), Expect = 5e-12
 Identities = 39/90 (43%), Positives = 48/90 (53%), Gaps = 3/90 (3%)

Query: 50  PPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE 109
           PP L   +   +   S   EE+  EE+  EE+  EE+    +  E EEE  EEEEEEEEE
Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930

Query: 110 EEEEEEEEEEEVSFSLATRERETETEEKRL 139
            EEE EEEE E+       E E E EE+ L
Sbjct: 931 FEEEFEEEEGELE---EEEEEEDEEEEEEL 957



 Score = 60.8 bits (146), Expect = 4e-10
 Identities = 41/112 (36%), Positives = 56/112 (50%), Gaps = 6/112 (5%)

Query: 25  TFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRRE 84
           T P P    E   G      +++E+   +  + +     + +  EE+  EE+  EE   E
Sbjct: 854 TLPPPQLVPEGTPG-GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912

Query: 85  EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEE 136
           E+  E +  E+EEE+EEE EEE EEEE E EEEEEE        E E E EE
Sbjct: 913 EEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE-----EDEEEEEELEE 959



 Score = 55.8 bits (133), Expect = 1e-08
 Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 2/104 (1%)

Query: 29  PHSKRENLAGLT-NSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKR 87
           P +  E+L  +  NS+   +EE              +    EE+  EE+  EE+  EE+ 
Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930

Query: 88  REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERE 131
            E +  E+E E EEEEEE E+EEEEEE EE E++ F  A  E E
Sbjct: 931 FEEEFEEEEGELEEEEEE-EDEEEEEELEEVEDLEFGTAGGEVE 973



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 22/52 (42%), Positives = 29/52 (55%)

Query: 69  EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           EE+  EE+  EE   EE   E +  E++EE+EEE EE E+ E      E EE
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974



 Score = 32.0 bits (71), Expect = 0.18
 Identities = 19/53 (35%), Positives = 28/53 (52%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEE 116
           + +  EE+  EE+  EE+   E+  E +  E+EEE EE E+ E      E EE
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974



 Score = 29.6 bits (65), Expect = 0.88
 Identities = 18/52 (34%), Positives = 27/52 (51%)

Query: 66  QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117
           +  EE+   E+  EE+  E +  E +  E+EEE+ EE E+ E      E EE
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974



 Score = 27.7 bits (60), Expect = 3.3
 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 3/113 (2%)

Query: 16   PENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREE 75
            PE +  LL     P ++ E  A  T  T + +  P        G S       +E   EE
Sbjct: 999  PEPEPGLLLEVEEPGTEEERGAD-TAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEE 1057

Query: 76   KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE--EEEEEEEVSFSLA 126
                    EE+  +G  + +   +   EEE E E E E  +E+E+++ +  LA
Sbjct: 1058 PSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLA 1110



 Score = 26.2 bits (56), Expect = 9.7
 Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 85   EKRREGKRREKEEEKEEEEEEEE-------EEEEEEEEEEEEEVSFSLATRERETETEEK 137
            E  REG+        +E  EEE        EEE E+  ++ +    + A  E ETETE +
Sbjct: 1036 EVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAE 1095

Query: 138  RL 139
             L
Sbjct: 1096 AL 1097


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 63.9 bits (154), Expect = 4e-11
 Identities = 34/67 (50%), Positives = 48/67 (71%), Gaps = 3/67 (4%)

Query: 61   SARKSQRREEKR---REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117
            SA+K++  E +R   +++KRR  K +E+   E K   +EEE+E+EEEEEEEEEEEEEEE+
Sbjct: 1368 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1427

Query: 118  EEEVSFS 124
            E + S S
Sbjct: 1428 ENDDSKS 1434



 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 29/61 (47%), Positives = 41/61 (67%)

Query: 60   TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
            T + K    EE +R  K+++++RR + + +     K   +EEEEE+EEEEEEEEEEEEEE
Sbjct: 1366 TRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1425

Query: 120  E 120
            E
Sbjct: 1426 E 1426



 Score = 54.3 bits (129), Expect = 3e-08
 Identities = 27/85 (31%), Positives = 49/85 (57%), Gaps = 2/85 (2%)

Query: 37   AGLTNSTSSVKEEPPTLRHSMAGTSARKSQR--REEKRREEKRREEKRREEKRREGKRRE 94
            +G++   S  ++E      S       ++QR  +++K+R   + +E    E +   +  E
Sbjct: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1408

Query: 95   KEEEKEEEEEEEEEEEEEEEEEEEE 119
            +E+E+EEEEEEEEEEEEE+E ++ +
Sbjct: 1409 EEKEEEEEEEEEEEEEEEDENDDSK 1433



 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 16/91 (17%)

Query: 58   AGTSARKSQRREEKRR----------EEKRREEKRREEKRREGKRREKEEEKEEEEEEEE 107
            +G S   S+  +E+R           EE +R  K+++++RR   + +   E +   EEEE
Sbjct: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1408

Query: 108  EEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            EE+EEEEEEEEEE        E E E ++ +
Sbjct: 1409 EEKEEEEEEEEEE------EEEEEDENDDSK 1433



 Score = 50.1 bits (118), Expect = 6e-07
 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 33   RENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKR 92
            R  ++   +  S  +E   +   S +    R   R  +K   E+ +   ++++KRR  K 
Sbjct: 1333 RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV 1392

Query: 93   REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLISP 142
            +E    + +   EEEEEE+EEEEEEEEE        E E E E     SP
Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEE-------EEEEEEDENDDSKSP 1435



 Score = 48.1 bits (113), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 26/96 (27%)

Query: 63   RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEE------- 115
            +K +RR  K +E+   E K   E+  E K  E+EEE+EEEEEEEE+E ++ +        
Sbjct: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKE-EEEEEEEEEEEEEEDENDDSKSPGKGRKK 1441

Query: 116  ------------------EEEEEVSFSLATRERETE 133
                              +EEEE    +A RERE E
Sbjct: 1442 IRKILKDDKLRTETQNALKEEEERRKRIAERERERE 1477



 Score = 40.8 bits (94), Expect = 4e-04
 Identities = 22/86 (25%), Positives = 42/86 (48%)

Query: 46   VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE 105
            V+E+  +   S +     + +  EE+  EE+  EE   ++ +  GK R+K  +  ++++ 
Sbjct: 1392 VQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL 1451

Query: 106  EEEEEEEEEEEEEEEVSFSLATRERE 131
              E +   +EEEE     +   RERE
Sbjct: 1452 RTETQNALKEEEERRKRIAERERERE 1477



 Score = 33.5 bits (75), Expect = 0.061
 Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 10/112 (8%)

Query: 34   ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93
            +N     + + S + + P  RH +      K    + +  EEK+ + K  +E +   +R+
Sbjct: 1279 KNQVNSESDSDSEESKKPRYRHRLL---RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1335

Query: 94   EKEEEKEEEE-------EEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
               E+ E+ +       EE  E E+E+           L   +R  + ++KR
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1387



 Score = 32.3 bits (72), Expect = 0.14
 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 8/92 (8%)

Query: 53   LRHSMAGTSARKSQRREEKRREEKR-REEKRREEKRREGKRREKEEEKEEEEEEEEEEEE 111
            LRH +  +     + ++ K +E K  +   RR+    + +  + +E    EE  E E+E+
Sbjct: 1303 LRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1362

Query: 112  -------EEEEEEEEEVSFSLATRERETETEE 136
                   ++ E EE + S+    + R  + +E
Sbjct: 1363 RPRTRSAKKAELEENQRSYKQKKKRRRIKVQE 1394



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 15/41 (36%), Positives = 23/41 (56%)

Query: 68   REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108
            +++K R E +   K  EE+R+    RE+E EK  E  E E+
Sbjct: 1447 KDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED 1487



 Score = 29.6 bits (65), Expect = 0.88
 Identities = 12/46 (26%), Positives = 25/46 (54%)

Query: 74   EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
            E+   +++  E K+R GK+ E+    EE + +   E + + EE ++
Sbjct: 1250 EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1295



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 19/98 (19%), Positives = 42/98 (42%), Gaps = 4/98 (4%)

Query: 32   KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRR----EEKRREEKRREEKR 87
            +R NL+   N+         +     +  + +K QR   K++    +EK+R   R   KR
Sbjct: 1098 ERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKR 1157

Query: 88   REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125
            ++           E++++    E   +E++ + V+ +L
Sbjct: 1158 KQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENL 1195



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 16/67 (23%), Positives = 30/67 (44%)

Query: 64   KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
            K    EE +      E+   +++  EGK+R  ++ +E   +EE + +   E + + E S 
Sbjct: 1235 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1294

Query: 124  SLATRER 130
                R R
Sbjct: 1295 KPRYRHR 1301



 Score = 28.1 bits (61), Expect = 2.6
 Identities = 18/106 (16%), Positives = 44/106 (41%), Gaps = 4/106 (3%)

Query: 34  ENLAGLTNSTSSVKEEPPTLRHSMAG----TSARKSQRREEKRREEKRREEKRREEKRRE 89
           E+L     +  +V +E  T  H +      T ARK ++     +++  + E +   K+ +
Sbjct: 373 EDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVD 432

Query: 90  GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135
            +   +    EE+   +    E ++ + +EE  +  A    + + +
Sbjct: 433 SEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMD 478



 Score = 26.6 bits (57), Expect = 7.4
 Identities = 23/108 (21%), Positives = 46/108 (42%), Gaps = 5/108 (4%)

Query: 32   KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
            KR  L G ++          T ++SM       S +R   +R E R  E+R    +R  K
Sbjct: 1054 KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKR--LKRIELR--ERRNLSSKRNTK 1109

Query: 92   RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERET-ETEEKR 138
              +      + EE  E+ +++++    ++ +  +  ++R +  T  KR
Sbjct: 1110 EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKR 1157


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 63.9 bits (154), Expect = 4e-11
 Identities = 34/67 (50%), Positives = 48/67 (71%), Gaps = 3/67 (4%)

Query: 61   SARKSQRREEKR---REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117
            SA+K++  E +R   +++KRR  K +E+   E K   +EEE+E+EEEEEEEEEEEEEEE+
Sbjct: 1406 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1465

Query: 118  EEEVSFS 124
            E + S S
Sbjct: 1466 ENDDSKS 1472



 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 29/61 (47%), Positives = 41/61 (67%)

Query: 60   TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
            T + K    EE +R  K+++++RR + + +     K   +EEEEE+EEEEEEEEEEEEEE
Sbjct: 1404 TRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1463

Query: 120  E 120
            E
Sbjct: 1464 E 1464



 Score = 54.3 bits (129), Expect = 3e-08
 Identities = 27/85 (31%), Positives = 49/85 (57%), Gaps = 2/85 (2%)

Query: 37   AGLTNSTSSVKEEPPTLRHSMAGTSARKSQR--REEKRREEKRREEKRREEKRREGKRRE 94
            +G++   S  ++E      S       ++QR  +++K+R   + +E    E +   +  E
Sbjct: 1387 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1446

Query: 95   KEEEKEEEEEEEEEEEEEEEEEEEE 119
            +E+E+EEEEEEEEEEEEE+E ++ +
Sbjct: 1447 EEKEEEEEEEEEEEEEEEDENDDSK 1471



 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 16/91 (17%)

Query: 58   AGTSARKSQRREEKRR----------EEKRREEKRREEKRREGKRREKEEEKEEEEEEEE 107
            +G S   S+  +E+R           EE +R  K+++++RR   + +   E +   EEEE
Sbjct: 1387 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1446

Query: 108  EEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            EE+EEEEEEEEEE        E E E ++ +
Sbjct: 1447 EEKEEEEEEEEEE------EEEEEDENDDSK 1471



 Score = 50.1 bits (118), Expect = 6e-07
 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 33   RENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKR 92
            R  ++   +  S  +E   +   S +    R   R  +K   E+ +   ++++KRR  K 
Sbjct: 1371 RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV 1430

Query: 93   REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLISP 142
            +E    + +   EEEEEE+EEEEEEEEE        E E E E     SP
Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEE-------EEEEEEDENDDSKSP 1473



 Score = 48.1 bits (113), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 26/96 (27%)

Query: 63   RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEE------- 115
            +K +RR  K +E+   E K   E+  E K  E+EEE+EEEEEEEE+E ++ +        
Sbjct: 1421 QKKKRRRIKVQEDSSSENKSNSEEEEEEKE-EEEEEEEEEEEEEEDENDDSKSPGKGRKK 1479

Query: 116  ------------------EEEEEVSFSLATRERETE 133
                              +EEEE    +A RERE E
Sbjct: 1480 IRKILKDDKLRTETQNALKEEEERRKRIAERERERE 1515



 Score = 40.8 bits (94), Expect = 4e-04
 Identities = 22/86 (25%), Positives = 42/86 (48%)

Query: 46   VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE 105
            V+E+  +   S +     + +  EE+  EE+  EE   ++ +  GK R+K  +  ++++ 
Sbjct: 1430 VQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL 1489

Query: 106  EEEEEEEEEEEEEEEVSFSLATRERE 131
              E +   +EEEE     +   RERE
Sbjct: 1490 RTETQNALKEEEERRKRIAERERERE 1515



 Score = 33.5 bits (75), Expect = 0.061
 Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 10/112 (8%)

Query: 34   ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93
            +N     + + S + + P  RH +      K    + +  EEK+ + K  +E +   +R+
Sbjct: 1317 KNQVNSESDSDSEESKKPRYRHRLL---RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1373

Query: 94   EKEEEKEEEE-------EEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
               E+ E+ +       EE  E E+E+           L   +R  + ++KR
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1425



 Score = 32.3 bits (72), Expect = 0.14
 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 8/92 (8%)

Query: 53   LRHSMAGTSARKSQRREEKRREEKR-REEKRREEKRREGKRREKEEEKEEEEEEEEEEEE 111
            LRH +  +     + ++ K +E K  +   RR+    + +  + +E    EE  E E+E+
Sbjct: 1341 LRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1400

Query: 112  -------EEEEEEEEEVSFSLATRERETETEE 136
                   ++ E EE + S+    + R  + +E
Sbjct: 1401 RPRTRSAKKAELEENQRSYKQKKKRRRIKVQE 1432



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 15/41 (36%), Positives = 23/41 (56%)

Query: 68   REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108
            +++K R E +   K  EE+R+    RE+E EK  E  E E+
Sbjct: 1485 KDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED 1525



 Score = 29.6 bits (65), Expect = 0.88
 Identities = 12/46 (26%), Positives = 25/46 (54%)

Query: 74   EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
            E+   +++  E K+R GK+ E+    EE + +   E + + EE ++
Sbjct: 1288 EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1333



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 19/98 (19%), Positives = 42/98 (42%), Gaps = 4/98 (4%)

Query: 32   KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRR----EEKRREEKRREEKR 87
            +R NL+   N+         +     +  + +K QR   K++    +EK+R   R   KR
Sbjct: 1136 ERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKR 1195

Query: 88   REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125
            ++           E++++    E   +E++ + V+ +L
Sbjct: 1196 KQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENL 1233



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 16/67 (23%), Positives = 30/67 (44%)

Query: 64   KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
            K    EE +      E+   +++  EGK+R  ++ +E   +EE + +   E + + E S 
Sbjct: 1273 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1332

Query: 124  SLATRER 130
                R R
Sbjct: 1333 KPRYRHR 1339



 Score = 28.1 bits (61), Expect = 2.6
 Identities = 18/106 (16%), Positives = 44/106 (41%), Gaps = 4/106 (3%)

Query: 34  ENLAGLTNSTSSVKEEPPTLRHSMAG----TSARKSQRREEKRREEKRREEKRREEKRRE 89
           E+L     +  +V +E  T  H +      T ARK ++     +++  + E +   K+ +
Sbjct: 411 EDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVD 470

Query: 90  GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135
            +   +    EE+   +    E ++ + +EE  +  A    + + +
Sbjct: 471 SEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMD 516



 Score = 26.6 bits (57), Expect = 7.4
 Identities = 23/108 (21%), Positives = 46/108 (42%), Gaps = 5/108 (4%)

Query: 32   KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
            KR  L G ++          T ++SM       S +R   +R E R  E+R    +R  K
Sbjct: 1092 KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKR--LKRIELR--ERRNLSSKRNTK 1147

Query: 92   RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERET-ETEEKR 138
              +      + EE  E+ +++++    ++ +  +  ++R +  T  KR
Sbjct: 1148 EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKR 1195


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 63.2 bits (152), Expect = 7e-11
 Identities = 30/49 (61%), Positives = 38/49 (77%)

Query: 81  KRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRE 129
           K  EE+  E +  E+E+E+EEEEEEEEEEEEEEEEEEEEE + ++A  E
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGE 780



 Score = 58.2 bits (139), Expect = 2e-09
 Identities = 30/53 (56%), Positives = 37/53 (69%), Gaps = 7/53 (13%)

Query: 85  EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEK 137
           + +  GK  E+EEE++EEEEEE+EEEEEEEEEEEEE        E E E EE+
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEE-------EEEEEEEEEE 771



 Score = 57.8 bits (138), Expect = 3e-09
 Identities = 28/47 (59%), Positives = 35/47 (74%)

Query: 79  EEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL 125
           +E+  EE+  E +  E EEE+EEEEEEEEEEEEEEEEEEE   + +L
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVAL 778



 Score = 56.6 bits (135), Expect = 7e-09
 Identities = 26/40 (65%), Positives = 33/40 (82%)

Query: 78  REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117
           +EE+  EE+  E +  ++EEE+EEEEEEEEEEEEEEEEEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 56.2 bits (134), Expect = 9e-09
 Identities = 29/60 (48%), Positives = 36/60 (60%)

Query: 77  RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEE 136
           + EE+  EE   E +  E+EEE+EEEEEEEEEEEEEEEEE    V+       R   + E
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSE 791



 Score = 53.9 bits (128), Expect = 4e-08
 Identities = 25/40 (62%), Positives = 31/40 (77%)

Query: 76  KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEE 115
           K  EE+  E++  E +  E+EEE+EEEEEEEEEEEEEEEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 24/40 (60%), Positives = 31/40 (77%)

Query: 74  EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           +E+  EE+  EE+  E +  E+EEE+EEEEEEEEEEEEEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 51.2 bits (121), Expect = 3e-07
 Identities = 28/58 (48%), Positives = 36/58 (62%), Gaps = 8/58 (13%)

Query: 57  MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114
           +A    + + + EE+  EE   EE+  EE        E+EEE+EEEEEEEEEEEEEEE
Sbjct: 722 LAPVQPQANGKEEEEEEEEDEEEEEEDEE--------EEEEEEEEEEEEEEEEEEEEE 771



 Score = 28.5 bits (62), Expect = 2.0
 Identities = 20/92 (21%), Positives = 34/92 (36%), Gaps = 15/92 (16%)

Query: 64  KSQRREEKRREEKRREEKRREEKR---------------REGKRREKEEEKEEEEEEEEE 108
           +    EE+  EE+  EE+  EE+                R G   E  E   +  +E   
Sbjct: 746 EEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAP 805

Query: 109 EEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
                ++++E     S+A  + E E   K L+
Sbjct: 806 STLLADDQKESRGRASMADGDLEPEEGSKTLV 837


>gi|21735569 claspin [Homo sapiens]
          Length = 1339

 Score = 62.8 bits (151), Expect = 9e-11
 Identities = 32/70 (45%), Positives = 48/70 (68%), Gaps = 1/70 (1%)

Query: 69  EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEE-EEEEVSFSLAT 127
           E+   EE+  EE+  +E   +G+ + ++EEKEEE EEEEE+EEEEEEE  +E   F L++
Sbjct: 625 EDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSS 684

Query: 128 RERETETEEK 137
            E ET+ E++
Sbjct: 685 EEIETKDEKE 694



 Score = 44.7 bits (104), Expect = 3e-05
 Identities = 24/74 (32%), Positives = 42/74 (56%)

Query: 62  ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121
           A+  +  + +R EE+++ +   +    +G   E+EEE+E  +E EE+ EE+ E+EE+EE 
Sbjct: 599 AKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEE 658

Query: 122 SFSLATRERETETE 135
                 +E E E E
Sbjct: 659 LEEEEEKEEEEEEE 672



 Score = 43.9 bits (102), Expect = 5e-05
 Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 5/84 (5%)

Query: 55  HSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114
           H+  G   +  + + ++  + +R EE+   +KR+   + + E+  EEEEEEEEE  +E E
Sbjct: 587 HTKPGEKLQVLKAKLQEAMKLRRFEER---QKRQALFKLDNEDGFEEEEEEEEEMTDESE 643

Query: 115 EEEEEEVSFSLATRERETETEEKR 138
           E+ EE+V      +E E E EE++
Sbjct: 644 EDGEEKV--EKEEKEEELEEEEEK 665



 Score = 40.4 bits (93), Expect = 5e-04
 Identities = 24/79 (30%), Positives = 41/79 (51%)

Query: 59  GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           G S  K   + +  + + +   K R  + R+ ++   + + E+  EEEEEEEEE  +E E
Sbjct: 584 GASHTKPGEKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESE 643

Query: 119 EEVSFSLATRERETETEEK 137
           E+    +   E+E E EE+
Sbjct: 644 EDGEEKVEKEEKEEELEEE 662



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 23/87 (26%), Positives = 41/87 (47%)

Query: 32  KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
           KR+ L  L N     +EE      +       + +  +E++ EE   EE++ EE+  EG 
Sbjct: 615 KRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGN 674

Query: 92  RREKEEEKEEEEEEEEEEEEEEEEEEE 118
           +   E     EE E ++E+E ++E  +
Sbjct: 675 QETAEFLLSSEEIETKDEKEMDKENND 701



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 15/139 (10%)

Query: 11   SSASSPENDRILLSTFPYPHSKREN----------LAGLTNSTSSVKEEPPTLRHSMAGT 60
            SS   P  + + L +  +P  K E           L    N   S ++E     HS +G 
Sbjct: 968  SSMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDE-----HSDSGN 1022

Query: 61   SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
                    ++   E  +R EK + + R      ++ E    +   E+E + EE +E EE+
Sbjct: 1023 DLALEDHEDDDEEELLKRSEKLKRQMRLRKYLEDEAEVSGSDVGSEDEYDGEEIDEYEED 1082

Query: 121  VSFSLATRERETETEEKRL 139
            V   +   + E +++ K++
Sbjct: 1083 VIDEVLPSDEELQSQIKKI 1101



 Score = 37.0 bits (84), Expect = 0.006
 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 22/120 (18%)

Query: 41  NSTSSVKEEPPTLRH-----SMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREK 95
           NST    +   + +H       AG +  KS+RR EK   E+R+ EK R+ K++E K +E 
Sbjct: 140 NSTDFTTDRKSSKKHIHDKEGTAGKAKVKSKRRLEK---EERKMEKIRQLKKKETKNQED 196

Query: 96  EEEKE--------------EEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141
           + E+               E   E+E     E+EE  E +  ++  + ++ + +E  L S
Sbjct: 197 DVEQPFNDSGCLLVDKDLFETGLEDENNSPLEDEESLESIRAAVKNKVKKHKKKEPSLES 256



 Score = 27.3 bits (59), Expect = 4.4
 Identities = 16/69 (23%), Positives = 33/69 (47%)

Query: 74   EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133
            ++ + EE+  E + R  K R + E+   +  ++ +   EEEEE  E+  F +  ++   +
Sbjct: 1157 DDDQTEEQLDESEARWRKERIEREQWLRDMAQQGKITAEEEEEIGEDSQFMILAKKVTAK 1216

Query: 134  TEEKRLISP 142
              +K    P
Sbjct: 1217 ALQKNASRP 1225



 Score = 26.2 bits (56), Expect = 9.7
 Identities = 12/47 (25%), Positives = 26/47 (55%)

Query: 93   REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
            R+ ++++ EE+ +E E    +E  E E+    +A + + T  EE+ +
Sbjct: 1154 RDSDDDQTEEQLDESEARWRKERIEREQWLRDMAQQGKITAEEEEEI 1200


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 62.4 bits (150), Expect = 1e-10
 Identities = 30/76 (39%), Positives = 47/76 (61%), Gaps = 5/76 (6%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           RK QRR E+ RE +R+ E++RE +R   + R++E E+E E E E + E E + E+E E  
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE-- 342

Query: 123 FSLATRERETETEEKR 138
                R+R+TE + +R
Sbjct: 343 ---RKRKRQTEMDRER 355



 Score = 60.8 bits (146), Expect = 4e-10
 Identities = 30/80 (37%), Positives = 45/80 (56%)

Query: 59  GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           G   R+ QR  EK RE +   E++R+ +R   K RE+E+ ++E  E E + E+E + E+ 
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204

Query: 119 EEVSFSLATRERETETEEKR 138
                    RERETETE +R
Sbjct: 205 HSERGRERERERETETETER 224



 Score = 60.5 bits (145), Expect = 5e-10
 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 1/92 (1%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KE     RHS  G   R+ +R  E   E KR+ ++ R+ +R+  + REK+ E+E   E E
Sbjct: 197 KENKTEDRHSERGRE-RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            E ++E E E + +       +ERE +T+ KR
Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKR 287



 Score = 57.4 bits (137), Expect = 4e-09
 Identities = 28/76 (36%), Positives = 43/76 (56%), Gaps = 5/76 (6%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R+ +R  +  R+ +RR E+ RE +R+  ++RE+E E+E   + E E E E E E + E  
Sbjct: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334

Query: 123 FSLATRERETETEEKR 138
                R+RE E E KR
Sbjct: 335 -----RDREKERERKR 345



 Score = 57.0 bits (136), Expect = 5e-09
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 12/108 (11%)

Query: 31  SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90
           ++RE   G    T   +E     R   A     +   RE +R+ E+ R+++R  EK R+ 
Sbjct: 131 TEREGERGRDRQTDGQRERE---RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQ- 186

Query: 91  KRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           +RRE+E ++E+E + E+   E   E E E        RE ETETE KR
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERE--------RETETETERKR 226



 Score = 57.0 bits (136), Expect = 5e-09
 Identities = 27/76 (35%), Positives = 43/76 (56%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R+ QR+ E+ R+++R  EK R+E+R   ++REKE + E+   E   E E E E E E   
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETER 224

Query: 123 FSLATRERETETEEKR 138
                RER+ + + +R
Sbjct: 225 KRQTDRERDRQRKTER 240



 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 4/79 (5%)

Query: 63  RKSQRREEKR---REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
           ++ +RR EKR   RE  R+ E+RRE+ R   + R +E +++ E+E E + + E + + E+
Sbjct: 60  KERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREK 119

Query: 120 EVSFSLATRERETETEEKR 138
           E +     RERETE E +R
Sbjct: 120 ERNRQ-KERERETEREGER 137



 Score = 53.1 bits (126), Expect = 7e-08
 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 2/78 (2%)

Query: 63  RKSQRREEKRREEKRRE--EKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           R+++R  EK RE KR+   E  RE  R+ G+   ++ E+E E E E + +   E EE E 
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390

Query: 121 VSFSLATRERETETEEKR 138
                  +ERE +TE+ R
Sbjct: 391 DRDRDRQKERERQTEKDR 408



 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 54  RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           R      + +K + RE+ R+E + RE +R +E + E +  E+  E+E E E E E E + 
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226

Query: 114 EEEEEEEVSFSLATRERETETEEKR 138
           + + E +       RERE + E +R
Sbjct: 227 QTDRERDRQ-RKTEREREKQAERER 250



 Score = 51.6 bits (122), Expect = 2e-07
 Identities = 25/86 (29%), Positives = 48/86 (55%), Gaps = 1/86 (1%)

Query: 54  RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE-EEEE 112
           R+   G   R+   RE +R  E+ R+  R  E+R   + R++++E+E + E++ + + E 
Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414

Query: 113 EEEEEEEEVSFSLATRERETETEEKR 138
           E++ E E+   S   RER  E E+++
Sbjct: 415 EKQREREKDRESERGRERGREREKQK 440



 Score = 50.8 bits (120), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 9/84 (10%)

Query: 63  RKSQRREEKRREEKR---REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
           RK +RR EK R  KR   RE +R  EK RE ++ ++E +++ E+E   ++E E E E E 
Sbjct: 77  RKRERRREKDRHRKRDRHRERQRDREKERE-RQTDRERDRQREKERNRQKERERETEREG 135

Query: 120 EVSFSLAT-----RERETETEEKR 138
           E      T     RER+ + E++R
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKER 159



 Score = 50.8 bits (120), Expect = 4e-07
 Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 5/112 (4%)

Query: 32  KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
           +RE      N T     E    R     T     ++R+  R  +++R+ +R  EK+ E +
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249

Query: 92  R---REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATR--ERETETEEKR 138
           R   RE E +KE E E + + + +  ++E E  +     R  ER+ ETE KR
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301



 Score = 50.8 bits (120), Expect = 4e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 16/88 (18%)

Query: 63  RKSQRREEKRREEKRREEKRREEKR---------------REGKRREKEEEKEEEEEEEE 107
           R+ +R  E++RE +R  EK RE KR               REG RR+ E E+E E E + 
Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG-RRQAERERERERERDR 379

Query: 108 EEEEEEEEEEEEEVSFSLATRERETETE 135
           +   E EE E +        RER+TE +
Sbjct: 380 QSAREREERERDRDRDRQKERERQTEKD 407



 Score = 50.4 bits (119), Expect = 5e-07
 Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 4/83 (4%)

Query: 60  TSARKSQRREEKRREEKRREEKRREEKRREGKR-REKEEEKEEEEEEEEEEEEEEEEEEE 118
           T  ++ ++RE +R  E+ R+ +R  E+ RE +R RE E ++E+E E + + + E + E  
Sbjct: 297 TERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERN 356

Query: 119 EEVSFS---LATRERETETEEKR 138
            +        A RERE E E  R
Sbjct: 357 RQTGREGRRQAERERERERERDR 379



 Score = 49.7 bits (117), Expect = 8e-07
 Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 3/79 (3%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE---EEEEEEEEEEEEEEEEE 119
           R+  R +E+ R+  R  +++RE++R   K RE+E E+E E   + + + + E E + + E
Sbjct: 97  RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156

Query: 120 EVSFSLATRERETETEEKR 138
           +       RER+ +TE  R
Sbjct: 157 KERERQTDRERQRQTERNR 175



 Score = 49.7 bits (117), Expect = 8e-07
 Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 12/83 (14%)

Query: 61  SARKSQRREEKRREEKRREEKRREEKRREGKR-----REKEEEKEEEEEEEEEEEEEEEE 115
           SAR+ + RE  R  ++++E +R+ EK R+G+R     RE+E+++E E   E   E E+++
Sbjct: 381 SAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK 440

Query: 116 EEEEEVSFSLATRERETETEEKR 138
             E +       RER+T+ +  R
Sbjct: 441 GRERD-------RERQTDRQAGR 456



 Score = 48.9 bits (115), Expect = 1e-06
 Identities = 25/81 (30%), Positives = 46/81 (56%), Gaps = 10/81 (12%)

Query: 61  SARKSQRREEKRREEKR---REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117
           S R+++R +E+ RE  R   R+ +++E +R+  ++R++  E++ E E + E + E E E 
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311

Query: 118 EEEVSFSLATRERETETEEKR 138
           E         R+RE E E +R
Sbjct: 312 ERN-------RKRERERERER 325



 Score = 47.8 bits (112), Expect = 3e-06
 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 13/86 (15%)

Query: 63  RKSQRREEKRREEKRREEKRRE-EKRREGKR---------REKEEEKEEEEEEEEEEEEE 112
           R++ R  +++RE++R  +K RE E  REG+R         RE+E +++ E+E E + + E
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166

Query: 113 EEEEEEEEVSFSLATRERETETEEKR 138
            + + E         RERE   +E+R
Sbjct: 167 RQRQTERN---RQKEREREKNRQERR 189



 Score = 47.0 bits (110), Expect = 5e-06
 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 54  RHSMAGTSARKSQRREEKRREEKRREEKRREEK-RREGKRREKEEEKEEEEEEEEEEEEE 112
           RH        + + RE++R  +  RE  R+ EK R   K RE+E E+E E   + + + +
Sbjct: 87  RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146

Query: 113 EEEEEEEEVSFSLATRERETETEEKR 138
            E E + +     A +ERE +T+ +R
Sbjct: 147 RERERQRD-----AEKERERQTDRER 167



 Score = 47.0 bits (110), Expect = 5e-06
 Identities = 19/76 (25%), Positives = 41/76 (53%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           RK++R  EK+ E +R  E+  E  +   + R+++ +++  ++E E + + + +   E   
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295

Query: 123 FSLATRERETETEEKR 138
            +   RER+ E E +R
Sbjct: 296 ETERKRERQRERERER 311



 Score = 46.6 bits (109), Expect = 7e-06
 Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 8/85 (9%)

Query: 54  RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           RH        K + R+  R  +++RE++R  +K RE +  E+E E+  + + + + E E 
Sbjct: 93  RHRERQRDREKERERQTDRERDRQREKERNRQKERE-RETEREGERGRDRQTDGQRERER 151

Query: 114 EEEEEEEVSFSLATRERETETEEKR 138
           + + E+E       RER+T+ E +R
Sbjct: 152 QRDAEKE-------RERQTDRERQR 169



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 21/64 (32%), Positives = 38/64 (59%), Gaps = 4/64 (6%)

Query: 63  RKSQRREEKRREEKRREEKRRE-EKRRE---GKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           ++ +R+ EK R+ +R  EK+RE EK RE   G+ R +E EK++  E + E + + +   +
Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457

Query: 119 EEVS 122
            + S
Sbjct: 458 RKRS 461



 Score = 36.6 bits (83), Expect = 0.007
 Identities = 20/72 (27%), Positives = 32/72 (44%)

Query: 67  RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126
           RR    +E  RR    +  K  +G  RE+  +KE E   E+ + E E + + E       
Sbjct: 28  RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87

Query: 127 TRERETETEEKR 138
            R+R+   E +R
Sbjct: 88  HRKRDRHRERQR 99



 Score = 34.7 bits (78), Expect = 0.027
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 1/79 (1%)

Query: 61  SARKSQRREEKRREEKRREEKRRE-EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
           S R+   +E  RR    +  K  + + R   +++E+E  +E+ + E E + + E   E++
Sbjct: 27  SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86

Query: 120 EVSFSLATRERETETEEKR 138
                   RER+ + E++R
Sbjct: 87  RHRKRDRHRERQRDREKER 105


>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
            sapiens]
          Length = 1108

 Score = 61.6 bits (148), Expect = 2e-10
 Identities = 44/115 (38%), Positives = 58/115 (50%), Gaps = 13/115 (11%)

Query: 28   YPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQ----RREEKRREEKRREEKRR 83
            Y + KRE  A   +ST   +  P  L +   G  A  SQ     RE   REE    EK  
Sbjct: 967  YSYCKRE--AEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEE 1024

Query: 84   EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            EE+ +E +  ++E+E E+ + +EEEEEEEEE EEEE         E E E EE +
Sbjct: 1025 EEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEE-------VEEAENEGEEAK 1072



 Score = 28.9 bits (63), Expect = 1.5
 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 54   RHSMAGT-SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112
            R S +G+ S   + R    +RE + R+   +EE   E    E    +    + + +E E 
Sbjct: 952  RFSHSGSYSQHMNHRYSYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERES 1011

Query: 113  --EEEEEEEEVSFSLATRERETETEEKRLISP 142
               EE+E+ E       +E E   EEK    P
Sbjct: 1012 LTREEDEDSEKEEEEEDKEMEELQEEKECEKP 1043



 Score = 27.7 bits (60), Expect = 3.3
 Identities = 25/107 (23%), Positives = 42/107 (39%), Gaps = 10/107 (9%)

Query: 32   KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
            +RE+L    +  S  +EE       M      K   + +   EE+  EE+  EE      
Sbjct: 1008 ERESLTREEDEDSEKEEEEED--KEMEELQEEKECEKPQGDEEEEEEEEEVEEE------ 1059

Query: 92   RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
              E EE + E EE + E   +++  E +  S      E   +  E++
Sbjct: 1060 --EVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEK 1104


>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
            sapiens]
          Length = 1124

 Score = 61.6 bits (148), Expect = 2e-10
 Identities = 44/115 (38%), Positives = 58/115 (50%), Gaps = 13/115 (11%)

Query: 28   YPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQ----RREEKRREEKRREEKRR 83
            Y + KRE  A   +ST   +  P  L +   G  A  SQ     RE   REE    EK  
Sbjct: 983  YSYCKRE--AEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEE 1040

Query: 84   EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            EE+ +E +  ++E+E E+ + +EEEEEEEEE EEEE         E E E EE +
Sbjct: 1041 EEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEE-------VEEAENEGEEAK 1088



 Score = 28.9 bits (63), Expect = 1.5
 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 54   RHSMAGT-SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112
            R S +G+ S   + R    +RE + R+   +EE   E    E    +    + + +E E 
Sbjct: 968  RFSHSGSYSQHMNHRYSYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERES 1027

Query: 113  --EEEEEEEEVSFSLATRERETETEEKRLISP 142
               EE+E+ E       +E E   EEK    P
Sbjct: 1028 LTREEDEDSEKEEEEEDKEMEELQEEKECEKP 1059



 Score = 27.7 bits (60), Expect = 3.3
 Identities = 25/107 (23%), Positives = 42/107 (39%), Gaps = 10/107 (9%)

Query: 32   KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
            +RE+L    +  S  +EE       M      K   + +   EE+  EE+  EE      
Sbjct: 1024 ERESLTREEDEDSEKEEEEED--KEMEELQEEKECEKPQGDEEEEEEEEEVEEE------ 1075

Query: 92   RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
              E EE + E EE + E   +++  E +  S      E   +  E++
Sbjct: 1076 --EVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEK 1120


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 49/131 (37%), Positives = 69/131 (52%), Gaps = 12/131 (9%)

Query: 12  SASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTL--RHSMAGTSARKSQRRE 69
           SA+ PE  +  L T     S   NL GLT   SSV + P T      +A +  + S+ ++
Sbjct: 383 SAAGPEQPQAGLLT----PSTLLNLGGLT---SSVLKTPITSVPLGPLASSPTKSSEGKD 435

Query: 70  EKRREEKRREEKRRE---EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126
               E +++E    +   EK    +   +EEE+EEE EEEEEEEEEEEEEEE+E    L 
Sbjct: 436 SGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLF 495

Query: 127 TRERETETEEK 137
             E + E E++
Sbjct: 496 PSELDEELEDR 506



 Score = 29.6 bits (65), Expect = 0.88
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 1/53 (1%)

Query: 58  AGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEE 110
           A   A + +  EE   EE+  EE+  EE+  EG +     E +EE E+   EE
Sbjct: 459 AEEEAEEEEEEEEAEEEEEEEEEE-EEEEEDEGCKGLFPSELDEELEDRPHEE 510



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 23/112 (20%), Positives = 52/112 (46%), Gaps = 6/112 (5%)

Query: 26   FPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREE 85
            FPY  +  + L GL  S  S+ ++    + S+     ++ QR+ ++++++K ++++ +  
Sbjct: 3342 FPYSPALSQALMGL--SPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKAS 3399

Query: 86   KRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEK 137
            +              +++  +E  + EE++    EVS  L     E E E K
Sbjct: 3400 QTPV----PPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESK 3447


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 37/97 (38%), Positives = 52/97 (53%), Gaps = 3/97 (3%)

Query: 40  TNSTSSVKEEPPTLRHSM---AGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE 96
           + S+ S KEE  +  +      G+S    ++      EE+  EE   E++  E    E E
Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDE 223

Query: 97  EEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133
           E  E+ EEEEEEEEEEEEEEEEEE  +    R+++ E
Sbjct: 224 EVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260



 Score = 53.5 bits (127), Expect = 6e-08
 Identities = 25/61 (40%), Positives = 39/61 (63%)

Query: 74  EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133
           EE   + +  EE   +G+  E+EEE+EEEEEEEEEEE E++E +++E      TR   ++
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272

Query: 134 T 134
           +
Sbjct: 273 S 273



 Score = 49.3 bits (116), Expect = 1e-06
 Identities = 24/67 (35%), Positives = 40/67 (59%)

Query: 69  EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATR 128
           EE    E+  EE    ++  E +  E+EEE+EEEEEEEEE E++E +++EE   +   + 
Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269

Query: 129 ERETETE 135
             ++ +E
Sbjct: 270 ASDSGSE 276



 Score = 46.2 bits (108), Expect = 9e-06
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 7/82 (8%)

Query: 63  RKSQRREEKRREEKRREEKRREEKR-------REGKRREKEEEKEEEEEEEEEEEEEEEE 115
           R++ R  +  +EE   EE   + +         +G   E EEE  EE+ EE+EE EE+ E
Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220

Query: 116 EEEEEVSFSLATRERETETEEK 137
           E+EE         E E E EE+
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEE 242



 Score = 40.0 bits (92), Expect = 7e-04
 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 10/91 (10%)

Query: 62  ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121
           A + +  +E   EE+  EE+  EE+  E +  E++E  ++EE  + +   E  +   E V
Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278

Query: 122 SF----------SLATRERETETEEKRLISP 142
           SF          +  + E++ E +  R ISP
Sbjct: 279 SFTDGSVRSGSGTDGSDEKKKERKRARGISP 309



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 1/58 (1%)

Query: 53  LRHSMAGTSARKSQRREEKR-REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE 109
           LR + A  S R+S+ RE  R RE  R  + RR+ +R  G+ RE+E E+  + + +  E
Sbjct: 646 LRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGE 703



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 32/140 (22%), Positives = 58/140 (41%), Gaps = 9/140 (6%)

Query: 6   HSRGFSS---ASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSA 62
           HSR   S   +SS  N++ ++ST     ++ +N     +  +   +    +R S +  S 
Sbjct: 65  HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLS-SSASR 123

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRR-----EKEEEKEEEEEEEEEEEEEEEEEE 117
              + + EK    KR  E+R +    +G  R     ++   +  +  +EE   EE   + 
Sbjct: 124 EPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDH 183

Query: 118 EEEVSFSLATRERETETEEK 137
           E   S S   +   TE EE+
Sbjct: 184 ETGSSGSSDEQGNNTENEEE 203



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 19/67 (28%), Positives = 25/67 (37%)

Query: 70  EKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRE 129
           E  R   R  +  +EE   E    + E       +E+    E EEE  EE+V       E
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217

Query: 130 RETETEE 136
              E EE
Sbjct: 218 DAEEDEE 224



 Score = 28.1 bits (61), Expect = 2.6
 Identities = 25/121 (20%), Positives = 37/121 (30%), Gaps = 14/121 (11%)

Query: 31  SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90
           + RE        T   K +P     S     + +     ++R     +  K        G
Sbjct: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180

Query: 91  KRREKEEEKEEEEEEEEEEEEEE--------------EEEEEEEVSFSLATRERETETEE 136
              E       +E+    E EEE              + EE+EEV       E E E EE
Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240

Query: 137 K 137
           +
Sbjct: 241 E 241


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 37/97 (38%), Positives = 52/97 (53%), Gaps = 3/97 (3%)

Query: 40  TNSTSSVKEEPPTLRHSM---AGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE 96
           + S+ S KEE  +  +      G+S    ++      EE+  EE   E++  E    E E
Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDE 223

Query: 97  EEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133
           E  E+ EEEEEEEEEEEEEEEEEE  +    R+++ E
Sbjct: 224 EVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260



 Score = 53.5 bits (127), Expect = 6e-08
 Identities = 25/61 (40%), Positives = 39/61 (63%)

Query: 74  EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133
           EE   + +  EE   +G+  E+EEE+EEEEEEEEEEE E++E +++E      TR   ++
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272

Query: 134 T 134
           +
Sbjct: 273 S 273



 Score = 49.3 bits (116), Expect = 1e-06
 Identities = 24/67 (35%), Positives = 40/67 (59%)

Query: 69  EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATR 128
           EE    E+  EE    ++  E +  E+EEE+EEEEEEEEE E++E +++EE   +   + 
Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269

Query: 129 ERETETE 135
             ++ +E
Sbjct: 270 ASDSGSE 276



 Score = 46.2 bits (108), Expect = 9e-06
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 7/82 (8%)

Query: 63  RKSQRREEKRREEKRREEKRREEKR-------REGKRREKEEEKEEEEEEEEEEEEEEEE 115
           R++ R  +  +EE   EE   + +         +G   E EEE  EE+ EE+EE EE+ E
Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220

Query: 116 EEEEEVSFSLATRERETETEEK 137
           E+EE         E E E EE+
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEE 242



 Score = 40.0 bits (92), Expect = 7e-04
 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 10/91 (10%)

Query: 62  ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121
           A + +  +E   EE+  EE+  EE+  E +  E++E  ++EE  + +   E  +   E V
Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278

Query: 122 SF----------SLATRERETETEEKRLISP 142
           SF          +  + E++ E +  R ISP
Sbjct: 279 SFTDGSVRSGSGTDGSDEKKKERKRARGISP 309



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 1/58 (1%)

Query: 53  LRHSMAGTSARKSQRREEKR-REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEE 109
           LR + A  S R+S+ RE  R RE  R  + RR+ +R  G+ RE+E E+  + + +  E
Sbjct: 664 LRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGE 721



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 32/140 (22%), Positives = 58/140 (41%), Gaps = 9/140 (6%)

Query: 6   HSRGFSS---ASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSA 62
           HSR   S   +SS  N++ ++ST     ++ +N     +  +   +    +R S +  S 
Sbjct: 65  HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLS-SSASR 123

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRR-----EKEEEKEEEEEEEEEEEEEEEEEE 117
              + + EK    KR  E+R +    +G  R     ++   +  +  +EE   EE   + 
Sbjct: 124 EPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDH 183

Query: 118 EEEVSFSLATRERETETEEK 137
           E   S S   +   TE EE+
Sbjct: 184 ETGSSGSSDEQGNNTENEEE 203



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 19/67 (28%), Positives = 25/67 (37%)

Query: 70  EKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRE 129
           E  R   R  +  +EE   E    + E       +E+    E EEE  EE+V       E
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217

Query: 130 RETETEE 136
              E EE
Sbjct: 218 DAEEDEE 224



 Score = 28.1 bits (61), Expect = 2.6
 Identities = 25/121 (20%), Positives = 37/121 (30%), Gaps = 14/121 (11%)

Query: 31  SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90
           + RE        T   K +P     S     + +     ++R     +  K        G
Sbjct: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180

Query: 91  KRREKEEEKEEEEEEEEEEEEEE--------------EEEEEEEVSFSLATRERETETEE 136
              E       +E+    E EEE              + EE+EEV       E E E EE
Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240

Query: 137 K 137
           +
Sbjct: 241 E 241


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 60.8 bits (146), Expect = 4e-10
 Identities = 26/84 (30%), Positives = 50/84 (59%)

Query: 55  HSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114
           H     + R+S+R++E+R  EKR+ E+ +E KR  GK+ +K+ +K E  +E E + +E E
Sbjct: 24  HISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83

Query: 115 EEEEEEVSFSLATRERETETEEKR 138
           ++ +E        R++E +  E++
Sbjct: 84  KQRKERREKERRKRKKEKKKRERK 107



 Score = 58.9 bits (141), Expect = 1e-09
 Identities = 30/107 (28%), Positives = 56/107 (52%)

Query: 32  KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
           KRE            KE     R +      ++ +RR++KRR+E++RE++R + +R+  K
Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162

Query: 92  RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           R+++E EK+ E   +E ++E E +E  E        R ++ E ++ R
Sbjct: 163 RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209



 Score = 56.2 bits (134), Expect = 9e-09
 Identities = 28/92 (30%), Positives = 56/92 (60%), Gaps = 1/92 (1%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KE+    R        +K + R+E+ RE K+R E++R+ KRR+ KRR++ + ++E  + E
Sbjct: 99  KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK-KRRKKKRRKERKREKERGKRE 157

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            + ++ ++EE E++   +   R++E E +E+R
Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKERR 189



 Score = 55.8 bits (133), Expect = 1e-08
 Identities = 25/90 (27%), Positives = 52/90 (57%)

Query: 49  EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108
           +P T R S      R+ ++R+ +R +E++RE  ++E+K+R+ + R KE E++ +E E++ 
Sbjct: 27  KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86

Query: 109 EEEEEEEEEEEEVSFSLATRERETETEEKR 138
           +E  E+E  + +       R++    E K+
Sbjct: 87  KERREKERRKRKKEKKKRERKQRGRRERKK 116



 Score = 54.7 bits (130), Expect = 3e-08
 Identities = 24/75 (32%), Positives = 49/75 (65%), Gaps = 3/75 (4%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R+ +R+ E+ ++EK++ +KR   K RE KR+E+E++++E  E+E  + ++E+++ E +  
Sbjct: 50  REKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK-- 107

Query: 123 FSLATRERETETEEK 137
                RER+ + E K
Sbjct: 108 -QRGRRERKKKKERK 121



 Score = 53.5 bits (127), Expect = 6e-08
 Identities = 24/76 (31%), Positives = 46/76 (60%), Gaps = 5/76 (6%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           RK + ++ K R EK R ++++E+K+RE K+R + E K+++E +E E E ++  E + +  
Sbjct: 79  RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK-- 136

Query: 123 FSLATRERETETEEKR 138
                R+++   E KR
Sbjct: 137 ---KRRKKKRRKERKR 149



 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 29/95 (30%), Positives = 54/95 (56%), Gaps = 3/95 (3%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREE--KRREEKRRE-EKRREEKRREGKRREKEEEKEEEE 103
           K E    R    G   +K +++ E  K RE KR+E EK+R+E+R + +R+ K+E+K+ E 
Sbjct: 47  KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRER 106

Query: 104 EEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           ++    E ++++E +E    +   RER+ +   K+
Sbjct: 107 KQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141



 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 24/78 (30%), Positives = 49/78 (62%), Gaps = 2/78 (2%)

Query: 63  RKSQRRE--EKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           R+ QR+E  EK R ++++E+K+RE K+R  + R+K++E++E E E ++  E + ++  ++
Sbjct: 82  REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141

Query: 121 VSFSLATRERETETEEKR 138
                  RE+E    E++
Sbjct: 142 KRRKERKREKERGKRERK 159



 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 22/76 (28%), Positives = 46/76 (60%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R+ ++R ++R+ EK R ++ R+ K+R+ + REK+ E+  +E ++E E +E  E ++E   
Sbjct: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197

Query: 123 FSLATRERETETEEKR 138
                +ER+ + +  R
Sbjct: 198 ERRKKKERKKDRKTDR 213



 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 21/75 (28%), Positives = 48/75 (64%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           RK ++RE++R + +R+ +KR++E+R + + R ++E K+E E +E  E ++E ++E  +  
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203

Query: 123 FSLATRERETETEEK 137
                R+ + +T+ +
Sbjct: 204 ERKKDRKTDRQTDSQ 218



 Score = 48.1 bits (113), Expect = 2e-06
 Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 7/83 (8%)

Query: 63  RKSQRREEKRREEK---RREEKR---REEKRREGK-RREKEEEKEEEEEEEEEEEEEEEE 115
           R+ +++E+K+RE K   RRE K+   R+E+ RE K RRE++ +K  +++  +E + E+E 
Sbjct: 94  RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153

Query: 116 EEEEEVSFSLATRERETETEEKR 138
            + E         ERE + E  R
Sbjct: 154 GKRERKRKKRKKEEREKKRERNR 176



 Score = 48.1 bits (113), Expect = 2e-06
 Identities = 22/75 (29%), Positives = 48/75 (64%), Gaps = 2/75 (2%)

Query: 54  RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           R    G   RK ++R+++ RE+KR  E+ R+E+++E +R+E+ E K+E ++E  +++E +
Sbjct: 149 REKERGKRERKRKKRKKEEREKKR--ERNRKERKKERERKERRERKKERKKERRKKKERK 206

Query: 114 EEEEEEEVSFSLATR 128
           ++ + +  + S   R
Sbjct: 207 KDRKTDRQTDSQVFR 221



 Score = 33.5 bits (75), Expect = 0.061
 Identities = 16/71 (22%), Positives = 32/71 (45%)

Query: 32  KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
           KRE   G        +++    +        RK +R  ++RRE K+  +K R +K+   K
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207

Query: 92  RREKEEEKEEE 102
            R+ + + + +
Sbjct: 208 DRKTDRQTDSQ 218


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 60.8 bits (146), Expect = 4e-10
 Identities = 33/63 (52%), Positives = 43/63 (68%), Gaps = 3/63 (4%)

Query: 79  EEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRER---ETETE 135
           EE+  EE+  E +  EKEEEKEE+EEEEE+EEE+EE+EEEEE        E+   E +TE
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178

Query: 136 EKR 138
            +R
Sbjct: 179 IQR 181



 Score = 57.8 bits (138), Expect = 3e-09
 Identities = 27/55 (49%), Positives = 39/55 (70%)

Query: 66  QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           +  E +  EE+  EE++ EEK  + +  EKEEEKEE+EEEEE+E ++ EEE+ EE
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173



 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 1/65 (1%)

Query: 70  EKRREEKRREEKRREEKRREGKRREKEEEKEEE-EEEEEEEEEEEEEEEEEEVSFSLATR 128
           E+   E+  EE   EEK  E +  E+EEEKEEE EE+EEEEE+E ++ EEE+V   + T 
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178

Query: 129 ERETE 133
            + T+
Sbjct: 179 IQRTQ 183



 Score = 53.9 bits (128), Expect = 4e-08
 Identities = 25/67 (37%), Positives = 44/67 (65%)

Query: 74  EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133
           EE+  EE+  E +  E +  ++E+E+EEE+EEE+EE+EEEEE+E +++       E +TE
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178

Query: 134 TEEKRLI 140
            +  + +
Sbjct: 179 IQRTQYL 185



 Score = 46.6 bits (109), Expect = 7e-06
 Identities = 24/53 (45%), Positives = 37/53 (69%), Gaps = 2/53 (3%)

Query: 69  EEKRREEKRREEKRREEKRREGKRREKEE--EKEEEEEEEEEEEEEEEEEEEE 119
           EE+  EE+ +EE++ E++  E K  EKEE  E+EE+E ++ EEE+ EEE + E
Sbjct: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178



 Score = 44.7 bits (104), Expect = 3e-05
 Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 1/55 (1%)

Query: 69  EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           EE+ +EE++ E++  EEK  E K  ++EEE++E ++ EEE+ EEE + E +   +
Sbjct: 131 EEEEKEEEKEEDEEEEEKEEE-KEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQY 184



 Score = 43.9 bits (102), Expect = 5e-05
 Identities = 23/76 (30%), Positives = 37/76 (48%)

Query: 37  AGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE 96
           A L     S ++  P     +        +  +E+ +EE   EE++ EEK  + +  EKE
Sbjct: 103 AALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162

Query: 97  EEKEEEEEEEEEEEEE 112
            +K EEE+ EEE + E
Sbjct: 163 GKKMEEEKVEEEIDTE 178


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 60.5 bits (145), Expect = 5e-10
 Identities = 36/132 (27%), Positives = 68/132 (51%), Gaps = 11/132 (8%)

Query: 7   SRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQ 66
           SR  + + S + DR    +   PH KR        S S         +        ++ +
Sbjct: 335 SRSHNRSRSRQKDRRRSKS---PHKKRSKSRERRKSRSRSHSRD---KRKDTREKIKEKE 388

Query: 67  RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126
           R +EK RE++R  EK RE+++  GK +++++E+E++ E+++E++ E E E+E E      
Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE-----K 443

Query: 127 TRERETETEEKR 138
            R++E E E+ +
Sbjct: 444 DRDKEKEKEQDK 455



 Score = 53.1 bits (126), Expect = 7e-08
 Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 8/138 (5%)

Query: 6   HSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKS 65
           H+R  S +SS  + R   S     H  R +    +      + + P  + S +    RKS
Sbjct: 311 HTRSKSRSSSKSHSRRKRSQSK--HRSRSHNRSRSRQKDRRRSKSPHKKRSKS-RERRKS 367

Query: 66  QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE-EEEEE----EEEEEEEEEEEEE 120
           + R   R + K   EK +E++R + K REKE E+E+E E+E+E    ++ ++E E++ E+
Sbjct: 368 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK 427

Query: 121 VSFSLATRERETETEEKR 138
                  RERE E E+ R
Sbjct: 428 DKEKDREREREKEHEKDR 445



 Score = 51.2 bits (121), Expect = 3e-07
 Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 10/89 (11%)

Query: 59  GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           G +  + + RE+ R ++K ++ +R  EK  E K R+KE+EKE+++E+E E++  +E +E+
Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKEHE-KDRDKEKEKEQDKEKEREKDRSKEIDEK 470

Query: 119 EEV---------SFSLATRERETETEEKR 138
            +          S++ + R R +  E +R
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRR 499



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 25/112 (22%), Positives = 57/112 (50%), Gaps = 3/112 (2%)

Query: 31  SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90
           S RE     + S+S       T++   + + + +S+ +++K+RE++R     R E+ R  
Sbjct: 493 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERST 552

Query: 91  KRREKEEEKEEEEEEEEEEE--EEEEEEEEEEVSFSLATRERET-ETEEKRL 139
             R+   +++ +E+ E+     +E+E  +E + S S    +++   TEE ++
Sbjct: 553 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 604



 Score = 36.2 bits (82), Expect = 0.009
 Identities = 18/91 (19%), Positives = 39/91 (42%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           K   P   ++ +  S   S+ R  +R     R  +  +  +R+  R      + +++++ 
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 535

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEK 137
           E+E +   E  E E S S+     + + +EK
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKEK 566



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 7/78 (8%)

Query: 61  SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           ++R+S+    +RR  + R   R     +  KR+           +++++ E+E +   E 
Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 545

Query: 121 VSFSLATRERETETEEKR 138
                  RERE  T  ++
Sbjct: 546 -------RERERSTSMRK 556


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 60.5 bits (145), Expect = 5e-10
 Identities = 36/132 (27%), Positives = 68/132 (51%), Gaps = 11/132 (8%)

Query: 7   SRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQ 66
           SR  + + S + DR    +   PH KR        S S         +        ++ +
Sbjct: 219 SRSHNRSRSRQKDRRRSKS---PHKKRSKSRERRKSRSRSHSRD---KRKDTREKIKEKE 272

Query: 67  RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLA 126
           R +EK RE++R  EK RE+++  GK +++++E+E++ E+++E++ E E E+E E      
Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE-----K 327

Query: 127 TRERETETEEKR 138
            R++E E E+ +
Sbjct: 328 DRDKEKEKEQDK 339



 Score = 53.1 bits (126), Expect = 7e-08
 Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 8/138 (5%)

Query: 6   HSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKS 65
           H+R  S +SS  + R   S     H  R +    +      + + P  + S +    RKS
Sbjct: 195 HTRSKSRSSSKSHSRRKRSQSK--HRSRSHNRSRSRQKDRRRSKSPHKKRSKS-RERRKS 251

Query: 66  QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE-EEEEE----EEEEEEEEEEEEE 120
           + R   R + K   EK +E++R + K REKE E+E+E E+E+E    ++ ++E E++ E+
Sbjct: 252 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK 311

Query: 121 VSFSLATRERETETEEKR 138
                  RERE E E+ R
Sbjct: 312 DKEKDREREREKEHEKDR 329



 Score = 51.2 bits (121), Expect = 3e-07
 Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 10/89 (11%)

Query: 59  GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           G +  + + RE+ R ++K ++ +R  EK  E K R+KE+EKE+++E+E E++  +E +E+
Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREKEHE-KDRDKEKEKEQDKEKEREKDRSKEIDEK 354

Query: 119 EEV---------SFSLATRERETETEEKR 138
            +          S++ + R R +  E +R
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRR 383



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 25/112 (22%), Positives = 57/112 (50%), Gaps = 3/112 (2%)

Query: 31  SKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREG 90
           S RE     + S+S       T++   + + + +S+ +++K+RE++R     R E+ R  
Sbjct: 377 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERST 436

Query: 91  KRREKEEEKEEEEEEEEEEE--EEEEEEEEEEVSFSLATRERET-ETEEKRL 139
             R+   +++ +E+ E+     +E+E  +E + S S    +++   TEE ++
Sbjct: 437 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 488



 Score = 36.2 bits (82), Expect = 0.009
 Identities = 18/91 (19%), Positives = 39/91 (42%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           K   P   ++ +  S   S+ R  +R     R  +  +  +R+  R      + +++++ 
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 419

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEK 137
           E+E +   E  E E S S+     + + +EK
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKEK 450



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 7/78 (8%)

Query: 61  SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           ++R+S+    +RR  + R   R     +  KR+           +++++ E+E +   E 
Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 429

Query: 121 VSFSLATRERETETEEKR 138
                  RERE  T  ++
Sbjct: 430 -------RERERSTSMRK 440


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 60.1 bits (144), Expect = 6e-10
 Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 12/107 (11%)

Query: 46  VKEEPPTLRHSMAGTSARKSQRREEKRR--EEKRREEKRREEKRREGKRREKEEE----- 98
           ++E+    R  +A    R  Q++E++RR  E++RRE + R ++ RE +RRE+EE+     
Sbjct: 381 LREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEE 440

Query: 99  -----KEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
                KEEEE    EEE+   E E+E +   L   +R  E  +++L+
Sbjct: 441 LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487



 Score = 47.0 bits (110), Expect = 5e-06
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 16/103 (15%)

Query: 52  TLRHSMAGTSARKSQRREEKRREEKRREEKRRE----------------EKRREGKRREK 95
           TLR           +R E  RR++  +E++ RE                E+++E +RR +
Sbjct: 351 TLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE 410

Query: 96  EEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           E+++ E E   ++E E+   E+EE+       R R+ E E +R
Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KE    LR        ++ Q RE++  + +   E+++  ++++ +RR  EE++  E E  
Sbjct: 364 KERSEALRRQQL---LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR 420

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            ++E E+   E+EE         R  E EE+R
Sbjct: 421 RQQEREQRRREQEEKRRLEELERRRKEEEERR 452



 Score = 40.4 bits (93), Expect = 5e-04
 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 10/99 (10%)

Query: 49  EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE------- 101
           EP ++ +    ++ R+   R ++  +E R E  RR++  +E + RE+EE K +       
Sbjct: 339 EPSSIVNVPGESTLRRDFLRLQQENKE-RSEALRRQQLLQEQQLREQEEYKRQLLAERQK 397

Query: 102 --EEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
             E+++E+    EE++  E E        +R  E EEKR
Sbjct: 398 RIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436



 Score = 34.3 bits (77), Expect = 0.036
 Identities = 18/48 (37%), Positives = 26/48 (54%)

Query: 73  REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           R++    + R + K    + R+K  EK+E E E    EEEEEE  E+E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE 337



 Score = 32.3 bits (72), Expect = 0.14
 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 68  REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           R++    + R + K   ++ R+ KR EK+E + E    EEEEEE  E+E E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRK-KRGEKDETEYEYSGSEEEEEEVPEQEGE 339



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 18/50 (36%), Positives = 24/50 (48%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           + Q  E + R + +    R  +KR E    E E    EEEEEE  E+E E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339



 Score = 28.1 bits (61), Expect = 2.6
 Identities = 17/56 (30%), Positives = 26/56 (46%)

Query: 53  LRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108
           L+H        + Q R + +    R  +KR E+   E +    EEE+EE  E+E E
Sbjct: 284 LKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 60.1 bits (144), Expect = 6e-10
 Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 12/107 (11%)

Query: 46  VKEEPPTLRHSMAGTSARKSQRREEKRR--EEKRREEKRREEKRREGKRREKEEE----- 98
           ++E+    R  +A    R  Q++E++RR  E++RRE + R ++ RE +RRE+EE+     
Sbjct: 381 LREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEE 440

Query: 99  -----KEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
                KEEEE    EEE+   E E+E +   L   +R  E  +++L+
Sbjct: 441 LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487



 Score = 47.0 bits (110), Expect = 5e-06
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 16/103 (15%)

Query: 52  TLRHSMAGTSARKSQRREEKRREEKRREEKRRE----------------EKRREGKRREK 95
           TLR           +R E  RR++  +E++ RE                E+++E +RR +
Sbjct: 351 TLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE 410

Query: 96  EEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           E+++ E E   ++E E+   E+EE+       R R+ E E +R
Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KE    LR        ++ Q RE++  + +   E+++  ++++ +RR  EE++  E E  
Sbjct: 364 KERSEALRRQQL---LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR 420

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            ++E E+   E+EE         R  E EE+R
Sbjct: 421 RQQEREQRRREQEEKRRLEELERRRKEEEERR 452



 Score = 40.4 bits (93), Expect = 5e-04
 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 10/99 (10%)

Query: 49  EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE------- 101
           EP ++ +    ++ R+   R ++  +E R E  RR++  +E + RE+EE K +       
Sbjct: 339 EPSSIVNVPGESTLRRDFLRLQQENKE-RSEALRRQQLLQEQQLREQEEYKRQLLAERQK 397

Query: 102 --EEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
             E+++E+    EE++  E E        +R  E EEKR
Sbjct: 398 RIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436



 Score = 34.3 bits (77), Expect = 0.036
 Identities = 18/48 (37%), Positives = 26/48 (54%)

Query: 73  REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           R++    + R + K    + R+K  EK+E E E    EEEEEE  E+E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE 337



 Score = 32.3 bits (72), Expect = 0.14
 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 68  REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           R++    + R + K   ++ R+ KR EK+E + E    EEEEEE  E+E E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRK-KRGEKDETEYEYSGSEEEEEEVPEQEGE 339



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 18/50 (36%), Positives = 24/50 (48%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           + Q  E + R + +    R  +KR E    E E    EEEEEE  E+E E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339



 Score = 28.1 bits (61), Expect = 2.6
 Identities = 17/56 (30%), Positives = 26/56 (46%)

Query: 53  LRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108
           L+H        + Q R + +    R  +KR E+   E +    EEE+EE  E+E E
Sbjct: 284 LKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 60.1 bits (144), Expect = 6e-10
 Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 12/107 (11%)

Query: 46  VKEEPPTLRHSMAGTSARKSQRREEKRR--EEKRREEKRREEKRREGKRREKEEE----- 98
           ++E+    R  +A    R  Q++E++RR  E++RRE + R ++ RE +RRE+EE+     
Sbjct: 381 LREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEE 440

Query: 99  -----KEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
                KEEEE    EEE+   E E+E +   L   +R  E  +++L+
Sbjct: 441 LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487



 Score = 47.0 bits (110), Expect = 5e-06
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 16/103 (15%)

Query: 52  TLRHSMAGTSARKSQRREEKRREEKRREEKRRE----------------EKRREGKRREK 95
           TLR           +R E  RR++  +E++ RE                E+++E +RR +
Sbjct: 351 TLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE 410

Query: 96  EEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           E+++ E E   ++E E+   E+EE+       R R+ E E +R
Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           KE    LR        ++ Q RE++  + +   E+++  ++++ +RR  EE++  E E  
Sbjct: 364 KERSEALRRQQL---LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR 420

Query: 107 EEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            ++E E+   E+EE         R  E EE+R
Sbjct: 421 RQQEREQRRREQEEKRRLEELERRRKEEEERR 452



 Score = 40.4 bits (93), Expect = 5e-04
 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 10/99 (10%)

Query: 49  EPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE------- 101
           EP ++ +    ++ R+   R ++  +E R E  RR++  +E + RE+EE K +       
Sbjct: 339 EPSSIVNVPGESTLRRDFLRLQQENKE-RSEALRRQQLLQEQQLREQEEYKRQLLAERQK 397

Query: 102 --EEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
             E+++E+    EE++  E E        +R  E EEKR
Sbjct: 398 RIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436



 Score = 34.3 bits (77), Expect = 0.036
 Identities = 18/48 (37%), Positives = 26/48 (54%)

Query: 73  REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           R++    + R + K    + R+K  EK+E E E    EEEEEE  E+E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQE 337



 Score = 33.5 bits (75), Expect = 0.061
 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 2/81 (2%)

Query: 63  RKSQRREEKRR--EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           R+ +  EE+RR  EEKRR E+ +E  RR+ +  ++  E  +++  +E+    E    E E
Sbjct: 443 RRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREME 502

Query: 121 VSFSLATRERETETEEKRLIS 141
                   +R+ + E+  L+S
Sbjct: 503 EHRQAERLQRQLQQEQAYLLS 523



 Score = 32.3 bits (72), Expect = 0.14
 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 68  REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           R++    + R + K   ++ R+ KR EK+E + E    EEEEEE  E+E E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRK-KRGEKDETEYEYSGSEEEEEEVPEQEGE 339



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 18/50 (36%), Positives = 24/50 (48%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           + Q  E + R + +    R  +KR E    E E    EEEEEE  E+E E
Sbjct: 290 RDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339



 Score = 28.1 bits (61), Expect = 2.6
 Identities = 17/56 (30%), Positives = 26/56 (46%)

Query: 53  LRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE 108
           L+H        + Q R + +    R  +KR E+   E +    EEE+EE  E+E E
Sbjct: 284 LKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE 339


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 60.1 bits (144), Expect = 6e-10
 Identities = 45/144 (31%), Positives = 65/144 (45%), Gaps = 20/144 (13%)

Query: 6   HSRGFSSASSPENDRILL---------STFPYPHSKRENLAGLTNSTSSVKEEPPTLRHS 56
           H    + +S PE DR            S+F   H +R+      N     +   P +RH 
Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRR---DNRERDQRPSSP-IRHQ 648

Query: 57  MAGTSARKSQRREEKR--REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114
                  + +RREE+R  R + RR+E+ RE  R   + RE+E E+E E + E E+E E E
Sbjct: 649 GRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELE 708

Query: 115 EEEEEEVSFSLATRERETETEEKR 138
            E   E       RERE E + +R
Sbjct: 709 RERARE-----REREREKERDRER 727



 Score = 60.1 bits (144), Expect = 6e-10
 Identities = 28/77 (36%), Positives = 43/77 (55%)

Query: 62  ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121
           AR+ +R  EK R+ +R  ++  + +R   + R++E+E+E E EE E E E E E E E  
Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERE 771

Query: 122 SFSLATRERETETEEKR 138
                 RER+ E E +R
Sbjct: 772 RERERARERDKERERQR 788



 Score = 57.4 bits (137), Expect = 4e-09
 Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 8/84 (9%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEE--------EEEEEEEEE 114
           R  +R  E+ RE  R  EK RE +R   + RE+E EKE + E         E E E E +
Sbjct: 685 RDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERD 744

Query: 115 EEEEEEVSFSLATRERETETEEKR 138
            E+E E       RERE E E +R
Sbjct: 745 REKEREREREERERERERERERER 768



 Score = 57.4 bits (137), Expect = 4e-09
 Identities = 32/80 (40%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 63  RKSQRREEKRRE---EKRREEKRREEKRREGKR-REKEEEKEEEEEEEEEEEEEEEEEEE 118
           R+  R  EK RE   E+ RE +R  EK R+ +R R+++ ++E E E E + E+E E E E
Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754

Query: 119 EEVSFSLATRERETETEEKR 138
           E        RERE E E +R
Sbjct: 755 ERERERERERERERERERER 774



 Score = 55.8 bits (133), Expect = 1e-08
 Identities = 32/79 (40%), Positives = 41/79 (51%), Gaps = 3/79 (3%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE---EEEEEEEEEEEEE 119
           R   RR+E+ RE  R  E+ RE +R   + R++E EKE E E E   E E E E+E + E
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726

Query: 120 EVSFSLATRERETETEEKR 138
                   RERE E E  R
Sbjct: 727 RDRDRDHDRERERERERDR 745



 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 3/79 (3%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE---EEEEEEEEEEEEEEEEE 119
           R+ +R  E+ RE +R  E+ RE +R   + REKE E E E   E E E E+E + E + +
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD 730

Query: 120 EVSFSLATRERETETEEKR 138
                   RERE + E++R
Sbjct: 731 RDHDRERERERERDREKER 749



 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 7/74 (9%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           + + R+  R  E+ RE  R +E+ RE + RE+E E+E E E E E E E   E ++E   
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKE--- 783

Query: 124 SLATRERETETEEK 137
               RER+ + E+K
Sbjct: 784 ----RERQRDWEDK 793



 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 11/86 (12%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKR---REKEEEKEEEEEEE--------EEEEEE 112
           + + R+ +R  E+ RE  R  EK RE +R   RE+E E+E+E + E         E E E
Sbjct: 681 RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740

Query: 113 EEEEEEEEVSFSLATRERETETEEKR 138
            E + E+E       RERE E E +R
Sbjct: 741 RERDREKEREREREERERERERERER 766



 Score = 51.6 bits (122), Expect = 2e-07
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R   R  E+ RE  R +E+ RE + RE + RE+E E+E E E E E   E ++E E +  
Sbjct: 731 RDHDRERERERERDREKEREREREERE-RERERERERERERERERERARERDKERERQRD 789

Query: 123 FSLATRERETETEEKRLI 140
           +    + R+   E++  I
Sbjct: 790 WEDKDKGRDDRREKREEI 807



 Score = 51.6 bits (122), Expect = 2e-07
 Identities = 24/75 (32%), Positives = 40/75 (53%)

Query: 64  KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           + + RE  R +E+ RE + RE +R   + RE+E E+E E   E ++E E + + E++   
Sbjct: 737 RERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKG 796

Query: 124 SLATRERETETEEKR 138
               RE+  E  E R
Sbjct: 797 RDDRREKREEIREDR 811



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 30/123 (24%), Positives = 51/123 (41%), Gaps = 21/123 (17%)

Query: 13  ASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLR--------HSMAGTSARK 64
           +SS ++   +    P P  KR      T S S  +   P LR        HS++    ++
Sbjct: 333 SSSSQSGSSIQRHSPSPRRKR------TPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQ 386

Query: 65  SQRREEKRREEKRREEKRR-------EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117
           S  R      EK R +  R         +RRE  R +++ EK+  EE E E+++    + 
Sbjct: 387 SPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDH 446

Query: 118 EEE 120
            ++
Sbjct: 447 RDD 449



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 15/111 (13%)

Query: 40   TNSTSSVKEEPPTLR--HSMAGTSARKSQRREEKR------REEKRREEKRREEKRREGK 91
            + S SS +  P + R  HS +G+   + + +E  R      RE +RR+ ++RE  R   K
Sbjct: 1270 SRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK 1329

Query: 92   ----RREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
                 R+++  +E E E E ++  + + E E  +S S+   ER+ + +  R
Sbjct: 1330 DWPRNRDRDRLRERERERERDKRRDLDRERERLISDSV---ERDRDRDRDR 1377



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 11/117 (9%)

Query: 24  STFPYP-HSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKR-REEKRREEK 81
           S  PYP HS          S+   K+ PP  R  M        +R  +   R  +RRE+ 
Sbjct: 370 SASPYPSHSL---------SSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDT 420

Query: 82  RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
           R +  R +  R E+E E+++    +  ++ E  +  +   +     R    ++ + R
Sbjct: 421 RGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR 477



 Score = 36.2 bits (82), Expect = 0.009
 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 17/107 (15%)

Query: 7    SRGFSSA-SSPENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKS 65
            SR  SS  SSPE+DR +       HS+    +G  +S   ++E     R        R+ 
Sbjct: 1270 SRSHSSRRSSPESDRQV-------HSR----SGSFDSRDRLQE-----RDRYEHDRERER 1313

Query: 66   QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112
            +RR+ ++RE  R  +K     R   + RE+E E+E ++  + + E E
Sbjct: 1314 ERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERE 1360



 Score = 35.0 bits (79), Expect = 0.021
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 64  KSQRREEKRREEKRREEKRREEKRRE---GKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
           K++R++     +KR  E+     R+E   G+ REKE+ K  +E   E EEE  E E   +
Sbjct: 90  KNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRD 149

Query: 121 VS 122
            S
Sbjct: 150 DS 151



 Score = 33.1 bits (74), Expect = 0.079
 Identities = 16/58 (27%), Positives = 29/58 (50%)

Query: 66  QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
           +R + KR++     +KR  E+     R+E    +  E+E+ +  +E   E EEE V +
Sbjct: 87  ERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEW 144



 Score = 30.8 bits (68), Expect = 0.39
 Identities = 13/36 (36%), Positives = 25/36 (69%)

Query: 71  KRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106
           K+ +EK + + R EEK R+GK R ++ E++ E+ ++
Sbjct: 278 KKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDK 313



 Score = 30.8 bits (68), Expect = 0.39
 Identities = 12/41 (29%), Positives = 26/41 (63%)

Query: 73  REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           R+ + +EE R+ E++   +R E++E KE+    +++ E+ E
Sbjct: 885 RQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTE 925



 Score = 30.4 bits (67), Expect = 0.52
 Identities = 20/81 (24%), Positives = 31/81 (38%)

Query: 59  GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
           G S R        RR  +R     RE  + + +  + E +K   EE      +E      
Sbjct: 62  GPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRH 121

Query: 119 EEVSFSLATRERETETEEKRL 139
            E      T+ER  E+EE+ +
Sbjct: 122 REKEDIKITKERTPESEEENV 142



 Score = 30.4 bits (67), Expect = 0.52
 Identities = 26/116 (22%), Positives = 47/116 (40%), Gaps = 6/116 (5%)

Query: 30  HSKRENLAGLTNSTSSVKEEPPTLR--HSMAGTSARKSQRREEKRR----EEKRREEKRR 83
           H +R++     N  S    + P  R  HS    +      + EK R      + +E +  
Sbjct: 817 HDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSL 876

Query: 84  EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
                   R+ + +E++ + E +E     EE+E +E+VS     RE+    E  R+
Sbjct: 877 SPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRM 932



 Score = 30.4 bits (67), Expect = 0.52
 Identities = 19/99 (19%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 40   TNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEK 99
            + STSS +++  +  HS   +S    ++   +      R+  +  ++    + RE+E   
Sbjct: 1260 SRSTSSDRQDSRS--HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRD 1317

Query: 100  EEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
              + E + + +++     + +    L  RERE E +++R
Sbjct: 1318 TRQREWDRDADKDWPRNRDRD---RLRERERERERDKRR 1353



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 17/68 (25%), Positives = 36/68 (52%), Gaps = 1/68 (1%)

Query: 65  SQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFS 124
           ++ R+ + +EE R+ E R+E  RR  ++  KE+    +++ E+ E  E      +++   
Sbjct: 882 TEDRQGRWKEEDRKPE-RKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGH 940

Query: 125 LATRERET 132
             + +RET
Sbjct: 941 HQSEDRET 948



 Score = 29.6 bits (65), Expect = 0.88
 Identities = 20/102 (19%), Positives = 40/102 (39%), Gaps = 4/102 (3%)

Query: 30  HSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRRE 89
           H +RE+  G  +     +EE    R      S+ +  R + + R+ + R + R    RRE
Sbjct: 414 HERREDTRGKRDREKDSREE----REYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRE 469

Query: 90  GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERE 131
            +      +  E  +   + +E  +  +      +   R+RE
Sbjct: 470 LRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDRE 511



 Score = 29.6 bits (65), Expect = 0.88
 Identities = 14/47 (29%), Positives = 21/47 (44%)

Query: 68  REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114
           R+ + R+  R+E+   EE R  G+   +EE    E   E   E   E
Sbjct: 508 RDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSE 554



 Score = 29.6 bits (65), Expect = 0.88
 Identities = 16/68 (23%), Positives = 34/68 (50%), Gaps = 5/68 (7%)

Query: 60  TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE----- 114
           T  R+ + +EE R+ E++   +R EE+  + K    ++++E+ E  E      ++     
Sbjct: 882 TEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHH 941

Query: 115 EEEEEEVS 122
           + E+ E S
Sbjct: 942 QSEDRETS 949



 Score = 26.6 bits (57), Expect = 7.4
 Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV- 121
           R ++      R+E  R   R +E  +  K R  E E+E  E E   ++ +  +   + V 
Sbjct: 103 RNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVH 162

Query: 122 SFSLATRERETETEEKRL 139
             SL  + ++ + E  +L
Sbjct: 163 ELSLEMKRQKIQRELMKL 180



 Score = 26.6 bits (57), Expect = 7.4
 Identities = 24/113 (21%), Positives = 40/113 (35%), Gaps = 18/113 (15%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKR-----------REEKRREGKR--- 92
           +EE    R         + + RE  R  +K RE +R           R EKR E +    
Sbjct: 753 REERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRN 812

Query: 93  ----REKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141
                ++ + K+    E      +  +   E    S A    + + E+ RL+S
Sbjct: 813 PRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLS 865


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 59.7 bits (143), Expect = 8e-10
 Identities = 34/115 (29%), Positives = 60/115 (52%), Gaps = 7/115 (6%)

Query: 27  PYPHSKRENLAGLT---NSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRR 83
           PYP   +E++  +    +    +  E    R +       K ++ +E++  EK R E+ R
Sbjct: 255 PYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERER 314

Query: 84  EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
            E+ RE +RRE+E E+E E E E+E+E E E E + +      T+ER+ + + +R
Sbjct: 315 -ERERERERREREREREREREREKEKERERERERDRDRD---RTKERDRDRDRER 365



 Score = 57.8 bits (138), Expect = 3e-09
 Identities = 27/84 (32%), Positives = 46/84 (54%)

Query: 54  RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           R+     S  KS+ RE +R  E+ RE +R  E+ RE +R  + E + E E++++ + EE+
Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436

Query: 114 EEEEEEEVSFSLATRERETETEEK 137
           EE+  E        RE+E   +E+
Sbjct: 437 EEDAYERRKLERKLREKEAAYQER 460



 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 1/83 (1%)

Query: 54  RHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
           R S       +S+ +   R  E+ RE +R  E+ RE + RE+E E+E E E E E++++ 
Sbjct: 373 RSSDRNKDRSRSREKSRDRERERERERERERERERE-REREREREREREREREREKDKKR 431

Query: 114 EEEEEEEVSFSLATRERETETEE 136
           + EE+EE ++     ER+   +E
Sbjct: 432 DREEDEEDAYERRKLERKLREKE 454



 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 26/76 (34%), Positives = 38/76 (50%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R  +R  ++ ++  R  EK R+ +R   + RE+E E+E E E E E E E E E E E  
Sbjct: 369 RDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKD 428

Query: 123 FSLATRERETETEEKR 138
                 E E +  E+R
Sbjct: 429 KKRDREEDEEDAYERR 444



 Score = 54.7 bits (130), Expect = 3e-08
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 7/76 (9%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R+  R  ++ R   R +++ R  ++   + RE+E E+E E E E E E E E E E E  
Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERE-- 420

Query: 123 FSLATRERETETEEKR 138
                RERE E ++KR
Sbjct: 421 -----REREREKDKKR 431



 Score = 54.3 bits (129), Expect = 3e-08
 Identities = 28/81 (34%), Positives = 47/81 (58%), Gaps = 4/81 (4%)

Query: 59  GTSARKSQRREEKRREEKRREEKRREEKRREGKR-REKEEEKEEEEEEEEEEEEEEEEEE 117
           G   ++ Q  E++RRE +R  E+ RE + RE +R RE+E EKE+E E E E + + +  +
Sbjct: 296 GKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTK 355

Query: 118 EEEVSFSLATRERETETEEKR 138
           E +       RER+ + + +R
Sbjct: 356 ERDRD---RDRERDRDRDRER 373



 Score = 51.6 bits (122), Expect = 2e-07
 Identities = 23/76 (30%), Positives = 43/76 (56%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R+ +R  E+ RE +R  E+ RE +R   + REK+++++ EE+EE+  E  + E +  E  
Sbjct: 395 REREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKE 454

Query: 123 FSLATRERETETEEKR 138
            +   R +  E  E++
Sbjct: 455 AAYQERLKNWEIRERK 470



 Score = 50.4 bits (119), Expect = 5e-07
 Identities = 25/89 (28%), Positives = 47/89 (52%), Gaps = 13/89 (14%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
           R+ +R  E+ RE +R  E+ RE +R   + ++K+ ++EE+EE+  E  + E +  E+E +
Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456

Query: 123 FSLATR-------------ERETETEEKR 138
           +    +             E+E E EE+R
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEER 485



 Score = 50.1 bits (118), Expect = 6e-07
 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 25/115 (21%)

Query: 47  KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKR------------------- 87
           +++P   R S      R  ++  E    +++RE++  EE R                   
Sbjct: 507 RDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRME 566

Query: 88  REGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLISP 142
           +E +RR + + K+E E EEEEEE++E+EE+ EE        E E E E+K  + P
Sbjct: 567 QEAERRRQPQIKQEPESEEEEEEKQEKEEKREE------PMEEEEEPEQKPCLKP 615



 Score = 46.6 bits (109), Expect = 7e-06
 Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 19/127 (14%)

Query: 23  LSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKR 82
           +S F   H K E   G        K+E              + + RE +RRE +R  E+ 
Sbjct: 281 ISKFRDTHKKLEEEKG--------KKEKERQEIEKERRERERERERERERRERERERERE 332

Query: 83  REEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSL-----------ATRERE 131
           RE ++ + + RE+E +++ +  +E + + + E + + +   S             +R+RE
Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRE 392

Query: 132 TETEEKR 138
            E E +R
Sbjct: 393 RERERER 399



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 21/87 (24%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKE----------EEKEEEEEEEEEEEEE 112
           R+ +R ++K+R+ +  EE   E ++ E K REKE          E +E ++  E E+E E
Sbjct: 421 REREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480

Query: 113 EEEEEEEEVSFSLATRERETETEEKRL 139
            EEE           R RE   E KRL
Sbjct: 481 REEE-----------RRREMAKEAKRL 496



 Score = 35.8 bits (81), Expect = 0.012
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 20/97 (20%)

Query: 63  RKSQRREEKR--REEKRREEKRREEKR------------------REGKRREKEEEKEEE 102
           RK  R  EK   REE+RR E  +E KR                  R    +++  ++E+E
Sbjct: 469 RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528

Query: 103 EEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
            E +E + + E+EE EE     LA    + + E +R+
Sbjct: 529 MEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRM 565



 Score = 33.5 bits (75), Expect = 0.061
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 17/92 (18%)

Query: 63  RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEE---------EEEEE 113
           R+   R+ + +E   +E  +  E R   K RE E+E E EEE   E         E  E+
Sbjct: 443 RRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED 502

Query: 114 EEEEEEEVSF--------SLATRERETETEEK 137
            +++ ++  +         L  RE+E E +E+
Sbjct: 503 YDDDRDDPKYYRGSALQKRLRDREKEMEADER 534



 Score = 27.7 bits (60), Expect = 3.3
 Identities = 13/46 (28%), Positives = 22/46 (47%)

Query: 46  VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
           +++E    R           +  EEK+ +E++REE   EE+  E K
Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610


>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
            sapiens]
          Length = 1925

 Score = 59.7 bits (143), Expect = 8e-10
 Identities = 34/62 (54%), Positives = 39/62 (62%)

Query: 76   KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135
            K+ +E R E     GK+ E EEEK EEEEEE EEEEEEEEE EEE        E+E E +
Sbjct: 1744 KQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERD 1803

Query: 136  EK 137
            EK
Sbjct: 1804 EK 1805



 Score = 50.4 bits (119), Expect = 5e-07
 Identities = 28/66 (42%), Positives = 44/66 (66%), Gaps = 2/66 (3%)

Query: 73   REEKRREEKRREEKRREGKRREKEEEKEEEE--EEEEEEEEEEEEEEEEEVSFSLATRER 130
            ++E+  EEK  EE+    +  E+EEE EEEE  +EE EE+EEE +E+EE+VS++      
Sbjct: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818

Query: 131  ETETEE 136
            + E++E
Sbjct: 1819 QPESQE 1824



 Score = 48.9 bits (115), Expect = 1e-06
 Identities = 28/64 (43%), Positives = 38/64 (59%)

Query: 75   EKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETET 134
            E  + ++ +E++        K+EE EEE+ EEEEEE EEEEEEEEE       +E   E 
Sbjct: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798

Query: 135  EEKR 138
            EE+R
Sbjct: 1799 EEER 1802



 Score = 43.9 bits (102), Expect = 5e-05
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%)

Query: 17   ENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEK 76
            +N   L+   P P S  E+  G        KE+ P       G   ++    E+   EE+
Sbjct: 1722 KNSLYLMPILPVPSSSWEDGKG-----KQPKEDRP---EHYPGLGKKEEGEEEKGEEEEE 1773

Query: 77   RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEE 111
              EE+  EE+  E +   KEE +E+EEE +E+EE+
Sbjct: 1774 ELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808



 Score = 35.0 bits (79), Expect = 0.021
 Identities = 19/51 (37%), Positives = 29/51 (56%)

Query: 89   EGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
            +GK ++ +E++ E      ++EE EEE+ EEE        E E ETEE+ L
Sbjct: 1740 DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEEL 1790


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 39/122 (31%), Positives = 59/122 (48%), Gaps = 16/122 (13%)

Query: 29   PHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREE--- 85
            P  K  +      S     EE  +L   +    +  S+  EE+  EE+R EE+ REE   
Sbjct: 2209 PKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEE 2268

Query: 86   -------------KRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERET 132
                         K  E K+++K+E+K+EE +E+EE  EE+EE   EE + SL+  E E 
Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328

Query: 133  ET 134
            E+
Sbjct: 2329 ES 2330



 Score = 58.5 bits (140), Expect = 2e-09
 Identities = 35/89 (39%), Positives = 54/89 (60%), Gaps = 7/89 (7%)

Query: 60   TSARKSQRREEKRREE---KRREEKRREEKRREGKRREKEEE----KEEEEEEEEEEEEE 112
            +S  + +R EE+ REE   +  EE+R+EE+  E K+ EKEEE    K++E+++EE +E+E
Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303

Query: 113  EEEEEEEEVSFSLATRERETETEEKRLIS 141
            E  EE+EE+     T     E EE+   S
Sbjct: 2304 EVFEEKEEIMSEEETESLSDEEEEEESCS 2332



 Score = 57.8 bits (138), Expect = 3e-09
 Identities = 42/120 (35%), Positives = 63/120 (52%), Gaps = 16/120 (13%)

Query: 34   ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93
            E+L        S+  E    R         + +  EE+R+EE+  EEK+ E++  E K++
Sbjct: 2231 ESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK 2290

Query: 94   EKEEEKEEEEEEEEEEEEEEE------------EEEEEEVSFSL---ATRERETETEEKR 138
            +KE++KEE +E+EE  EE+EE            EEEEEE S SL     RE+E   +EK+
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE-SCSLEEEVDREKEILKKEKQ 2349



 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 32/77 (41%), Positives = 44/77 (57%), Gaps = 3/77 (3%)

Query: 65   SQRREEKRREEKRREEKRR---EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121
            S + +E   EE   EE      E +++E    E+EEE+EEEEE EEEE  EEEEE +EE 
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273

Query: 122  SFSLATRERETETEEKR 138
                   E+E E ++K+
Sbjct: 2274 EGEEKQVEKEEEEKKKK 2290



 Score = 51.2 bits (121), Expect = 3e-07
 Identities = 33/87 (37%), Positives = 45/87 (51%), Gaps = 14/87 (16%)

Query: 67   RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE--------------EEEEEEEE 112
            +R  ++R+E +R +K +E+   +    E EE   EE E              EEEEE EE
Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253

Query: 113  EEEEEEEEVSFSLATRERETETEEKRL 139
            EEE EEEEV      R+ E E EEK++
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQV 2280



 Score = 49.7 bits (117), Expect = 8e-07
 Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 2/95 (2%)

Query: 46   VKEEPPTLRHSMAGTSARKSQRREEKRRE--EKRREEKRREEKRREGKRREKEEEKEEEE 103
            V+EE    +    G   +  +  EEK+++  EK++EE + +E+  E K     EE+ E  
Sbjct: 2262 VREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL 2321

Query: 104  EEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
             +EEEEEE    EEE +    +  +E++ + +E+R
Sbjct: 2322 SDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQR 2356



 Score = 40.0 bits (92), Expect = 7e-04
 Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 34   ENLAGLTNSTSSVK-EEPPTLRHSMAGTSARKSQRREEKRR--EEKRREEKRREEKRREG 90
            EN+    +     K EE  TL   ++     K Q+  E++R  +E+ +  +   ++ R  
Sbjct: 1526 ENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAE 1585

Query: 91   KRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
            K+R +EE K  +EEE+  +EE +  +EE +++
Sbjct: 1586 KKRAQEERKLAQEEEKLAQEERQLAQEERKLA 1617



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 9/117 (7%)

Query: 32   KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGK 91
            K   LA + N  +   EE P    ++       +Q  EE   + +    K  E  + EGK
Sbjct: 1682 KGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGK 1741

Query: 92   RREKEEEKEEEEE-----EEEEEEEEEEEEEEEEVSF----SLATRERETETEEKRL 139
              E++++  EEEE      E+  EEE +  +EEE+       LA  + +   EE+RL
Sbjct: 1742 LVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERL 1798



 Score = 36.6 bits (83), Expect = 0.007
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 7/72 (9%)

Query: 68   REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLAT 127
            RE + +E++  EE+R  ++  +  R  ++  + E++  +EE +  +EEE+       LA 
Sbjct: 1552 REGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK-------LAQ 1604

Query: 128  RERETETEEKRL 139
             ER+   EE++L
Sbjct: 1605 EERQLAQEERKL 1616



 Score = 35.4 bits (80), Expect = 0.016
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 8/81 (9%)

Query: 65   SQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEE-------EEEEEEEEEEEEEE 117
            S++R E  ++EK+   K+R+   +  +   KEE+  EEE        E   ++EEE   E
Sbjct: 2126 SEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185

Query: 118  EEEVSFSLATRERETETEEKR 138
            EEEV   L  R R+ + E KR
Sbjct: 2186 EEEVIPFLKRRWRKRK-EAKR 2205



 Score = 35.0 bits (79), Expect = 0.021
 Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 11/143 (7%)

Query: 4    YGHSRGFSSASSPENDRILLSTFPYPHSKRENLAGLTNSTSSVK----EEPPTLRHSMAG 59
            +G +R    A   E ++ LL      H   E L+         K    EE   +  +M  
Sbjct: 1471 HGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLS 1530

Query: 60   TSARKSQRREEKR---REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEE 116
            + +++ Q ++E+     EE  RE + +E++  E +R  +EE K      +    E++  +
Sbjct: 1531 SKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590

Query: 117  EEEEVSFSLATRERETETEEKRL 139
            EE +    LA  E +   EE++L
Sbjct: 1591 EERK----LAQEEEKLAQEERQL 1609



 Score = 32.3 bits (72), Expect = 0.14
 Identities = 19/64 (29%), Positives = 39/64 (60%), Gaps = 3/64 (4%)

Query: 60   TSARKSQRREEKRREEKRREEKRR--EEKRREGK-RREKEEEKEEEEEEEEEEEEEEEEE 116
            T  ++  ++EEK+  +K  ++ R+  +++R+ GK +RE  +E+ +  EE EE    EE+ 
Sbjct: 1382 TMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKV 1441

Query: 117  EEEE 120
             ++E
Sbjct: 1442 VKQE 1445



 Score = 31.6 bits (70), Expect = 0.23
 Identities = 21/98 (21%), Positives = 47/98 (47%), Gaps = 4/98 (4%)

Query: 46   VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE- 104
            V EE   ++         + + R EK+R ++ R+  + EEK  + +R+  +EE++  +  
Sbjct: 1561 VTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAY 1620

Query: 105  ---EEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
                +++ E  + E +  +   +LA R  +   E ++L
Sbjct: 1621 VKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKL 1658



 Score = 31.6 bits (70), Expect = 0.23
 Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 3/52 (5%)

Query: 62   ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
            ARK ++   K R    +EEK  EE   E K   K  E   ++EEE   EEEE
Sbjct: 2140 ARKQRKLANKMRRMINKEEKMTEE---ESKLARKHSEVILDDEEEGGIEEEE 2188



 Score = 30.8 bits (68), Expect = 0.39
 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%)

Query: 73   REEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERET 132
            +E  ++EEK+  +K    K+  K  +KE +  + + E  +EE +  EEV   +AT E + 
Sbjct: 1385 KEISKKEEKKTFQK--SPKQGRKAVQKERKVGKIKREMTKEERDMSEEVE-EMATLEEKV 1441

Query: 133  ETEEKRLI 140
              +E +L+
Sbjct: 1442 VKQEGKLV 1449



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 7/79 (8%)

Query: 68   REEKRREEKRREEKRREEKRREGKRREKEEEKEEEE-----EEEEEEEEEEEEEE-EEEV 121
            +EE++  +   +    EE  +E K+ + EE K+  E     + +E++ ++EEE   EEEV
Sbjct: 1491 QEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEV 1550

Query: 122  SFSLATRERETETEEKRLI 140
            S     +E++  TEE+R I
Sbjct: 1551 SREGEEKEQQV-TEEQRHI 1568



 Score = 30.0 bits (66), Expect = 0.67
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 16/98 (16%)

Query: 47   KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE---------- 96
            KEE       +      K ++++EK++EE + +E+  EEK       E E          
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329

Query: 97   ----EEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRER 130
                EE+ + E+E  ++E++ + +E+     SL  RER
Sbjct: 2330 SCSLEEEVDREKEILKKEKQFKLQEQRRK--SLRGRER 2365



 Score = 29.6 bits (65), Expect = 0.88
 Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 28/124 (22%)

Query: 39   LTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKR---REEKRREEKR------------- 82
            +T     ++EE    R       A K + +EE++    EEK  +E+R             
Sbjct: 1561 VTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAY 1620

Query: 83   -------REEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135
                   RE  + EGK  +KEE   +  E+  +E E+  ++ ++     LA +  +   E
Sbjct: 1621 VKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKK-----LAKKWEKVARE 1675

Query: 136  EKRL 139
            E++L
Sbjct: 1676 EEKL 1679



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 26/92 (28%), Positives = 49/92 (53%), Gaps = 13/92 (14%)

Query: 62   ARKSQRREEKRREEKRREEK--RREEK--RREGKRRE-------KEEEKEEEEEEEEEEE 110
            ++++++  +KR++  ++ EK  R EEK  ++ GK  E       K EE  + E+  + +E
Sbjct: 1652 SQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQE 1711

Query: 111  EEEEEEEEEEV--SFSLATRERETETEEKRLI 140
            +E  +E EE       L+ +E E   EE +L+
Sbjct: 1712 KELAQELEELEWDMEELSWKEEELNQEEGKLV 1743



 Score = 29.3 bits (64), Expect = 1.1
 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 18/86 (20%)

Query: 65   SQRREEKRREE-KRREEKRR--EEKRREGKRREKEEEKE----EEEE---EEEEEEEEEE 114
            S + EE  +EE K  EEK++  EE+     +REK  E+E    +EEE   +E+E+  + +
Sbjct: 1729 SWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK 1788

Query: 115  E---EEEEEVSFSLATRERETETEEK 137
            E   EEEE +      R+RE   E+K
Sbjct: 1789 EKMPEEEERLG-----RKREQLIEKK 1809



 Score = 27.3 bits (59), Expect = 4.4
 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 9/118 (7%)

Query: 32   KRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEK----RREEKRREEKR 87
            KR+ LA      +  +E+       +A      +Q+ EE  + E+    + +E  +E + 
Sbjct: 1661 KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEE 1720

Query: 88   REGKRRE---KEEEKEEEEEE--EEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
             E    E   KEEE  +EE +  EE+++  EEEE        L+  E +   EE+ LI
Sbjct: 1721 LEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLI 1778



 Score = 26.9 bits (58), Expect = 5.7
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 47   KEEPPTLRHSMAGTSARKSQRREEKRREEKRR----EEKRREEKRREGKRREKEEEKEEE 102
            +EE    +         K  + EE   +EK +    +EK  EE+ R G++RE+  EK+ +
Sbjct: 1752 EEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMK 1811

Query: 103  EEEEEEEEEEEEEE 116
              ++ E      EE
Sbjct: 1812 LAQKRERWINSMEE 1825



 Score = 26.2 bits (56), Expect = 9.7
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 45   SVKEEPPTLRHS-MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE 101
            S KEE  T + S   G  A + +R+  K + E  +EE+   E+  E    E++  K+E
Sbjct: 1388 SKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQE 1445



 Score = 26.2 bits (56), Expect = 9.7
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 2/76 (2%)

Query: 45   SVKEEPPTLRHSMAGTSARKSQRREEKR--REEKRREEKRREEKRREGKRREKEEEKEEE 102
            S KEE             +K    EE    + EK  EE+ +  +  E   +EKE+  + +
Sbjct: 1729 SWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK 1788

Query: 103  EEEEEEEEEEEEEEEE 118
            E+  EEEE    + E+
Sbjct: 1789 EKMPEEEERLGRKREQ 1804



 Score = 26.2 bits (56), Expect = 9.7
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 76   KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135
            ++R E  ++EK+   K+R K   K      +EE+  EEE +   + S  +   E E   E
Sbjct: 2127 EKRSELTKDEKKLARKQR-KLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185

Query: 136  EKRLI 140
            E+ +I
Sbjct: 2186 EEEVI 2190


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.296    0.117    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,083,536
Number of Sequences: 37866
Number of extensions: 516475
Number of successful extensions: 94723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2718
Number of HSP's successfully gapped in prelim test: 444
Number of HSP's that attempted gapping in prelim test: 6502
Number of HSP's gapped (non-prelim): 31356
length of query: 142
length of database: 18,247,518
effective HSP length: 92
effective length of query: 50
effective length of database: 14,763,846
effective search space: 738192300
effective search space used: 738192300
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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