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Search of human proteins with 239745089
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily
a-like [Homo sapiens]
(828 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 1698 0.0
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 1266 0.0
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 868 0.0
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 789 0.0
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 689 0.0
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 635 0.0
gi|239750781 PREDICTED: golgi autoantigen, golgin subfamily a-li... 426 e-119
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 424 e-118
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 423 e-118
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 406 e-113
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 366 e-101
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 296 7e-80
gi|148746195 trichohyalin [Homo sapiens] 295 2e-79
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 249 7e-66
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 248 1e-65
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 247 3e-65
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 246 5e-65
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 237 4e-62
gi|221219020 NYD-SP11 protein [Homo sapiens] 215 2e-55
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 212 1e-54
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 179 7e-45
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 179 7e-45
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 178 2e-44
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 174 4e-43
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 170 6e-42
gi|44890059 involucrin [Homo sapiens] 160 5e-39
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 160 6e-39
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 155 2e-37
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 155 2e-37
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 155 2e-37
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 1698 bits (4398), Expect = 0.0
Identities = 828/828 (100%), Positives = 828/828 (100%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET
Sbjct: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
Query: 61 TTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED 120
TTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED
Sbjct: 61 TTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED 120
Query: 121 GNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTI 180
GNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTI
Sbjct: 121 GNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTI 180
Query: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE
Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
Query: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Query: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 660
EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 660
Query: 661 KMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWG 720
KMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWG
Sbjct: 661 KMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWG 720
Query: 721 QEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGS 780
QEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGS
Sbjct: 721 QEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGS 780
Query: 781 PQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 828
PQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI
Sbjct: 781 PQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 828
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 1266 bits (3275), Expect = 0.0
Identities = 671/892 (75%), Positives = 709/892 (79%), Gaps = 153/892 (17%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGT ATDTKKKKIN+GTNPET
Sbjct: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPET 60
Query: 61 TTSEGCHSPED----------EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYY 110
TTS GCHSPED EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYY
Sbjct: 61 TTSGGCHSPEDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYY 120
Query: 111 SQDAARKFEDGNL----------------------------GESKDLAGRLHHSWHFAGE 142
SQDAARKFEDGNL GESKDLAGRLHHSWHFAGE
Sbjct: 121 SQDAARKFEDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGE 180
Query: 143 LQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESE 202
LQRALSAVST HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKL LAESE
Sbjct: 181 LQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESE 240
Query: 203 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE 262
KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE
Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE 300
Query: 263 RLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQ 322
RLREQEGKMREQEEKM RQEKRLREQEKELREQEKELREQK+LREQEEQMQEQEEKMWEQ
Sbjct: 301 RLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQ 360
Query: 323 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW 382
EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW
Sbjct: 361 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW 420
Query: 383 E--------------------QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
E QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
EQEDQMWEQEEKMRDQEQKMWDQEERM +++ ++KK W QEEKMREE++
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERM---------EKKTQEQEKKTWDQEEKMREEERM 591
Query: 543 QEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
+E+EKK ++EE MRE EE+M+E+E+KM+E+EE M EQEEKMQEQEEKM EQEEKMWEQE
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651
Query: 602 EKMQEQ------------------EEKMWEQEEKMWEQ---------------------- 621
EKM EQ +EKM EQEEK+WEQ
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711
Query: 622 ------------EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ---- 665
EEE+ M+EQEE M EQEEKMQEQEE+MWEQEEKM EQEEKM EQ
Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 666 --------------EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
+EK+ QEEKMR+QEEKM+GQEEKMR QEEKMRGQEEKMWGQEEKM
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 712 WGQEEKMWGQEE------------MREKEERIRDQKEKM---QERLPEHEER 748
WGQEEKMWGQEE M+ +EE++R+Q+EKM +E++ E EE+
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Score = 538 bits (1387), Expect = e-153
Identities = 314/668 (47%), Positives = 422/668 (63%), Gaps = 143/668 (21%)
Query: 127 KDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELK 186
K+L +L + ++Q W ++ EEL ++ + + + E L+
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQE-----EELREQEKKIRKQEEKMWRQEERLR 303
Query: 187 KKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
++ +++E+ ++ ++ KEL+ E+ K L Q + +E+M QEE++ EQ
Sbjct: 304 EQEGKMREQEEKMWRQEKRLREQEKELR---EQEKELREQKELREQEEQMQEQEEKMWEQ 360
Query: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK-- 304
E+K+R+QEEKMWRQEERL EQE +MREQE+KMR QE+R+ EQ++ LRE+E+ +REQ+K
Sbjct: 361 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW 420
Query: 305 ---------------------------------------------LREQEEQMQEQEEKM 319
+REQEE+MQ+QEE M
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 320 WEQEEK------MREQEEKMW------RQEERLWEQEKQMREQE------------QKMR 355
WEQEEK + EQ+EK+W QEE++WEQE+++R+QE +KMR
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 356 DQEERMWEQDERLREKEERMREQE------------KMWEQEEKMQEEERIREREKKMRE 403
+QE++MWEQ+E++R++E++M +QE K W+QEEKM+EEER+REREKKMRE
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 404 EEETMREQEEKMQ----------------------------KQEENMWEQEEKEWQQQRL 435
EEE MREQEEKMQ +QEE MWEQEEK W+QQRL
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 436 PEQKEKLW------EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
PEQKEKLW EQEKMQEQEEKIWEQE+ + +E QEKK W QEKMRE E+ M
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE---QEKKTWDQEKMRE-EESMR 716
Query: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQQEEKMREEKKTQEQEKK 548
E+E+KMR++E+ M +QEE+M EQ+E+++E+EE M EQ +KMW+QEEKM E+++ EQ++K
Sbjct: 717 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Query: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
W + EKM+E+E++ E+E+KMR++EE MR QEEKM+ QEEKMR QEEKMW QEEKM QE
Sbjct: 777 LW-EHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQE 835
Query: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
EKMW QEEKMW QEE + EEKMQ QEEKM EQEEKMR QEEKMREQEEK
Sbjct: 836 EKMWGQEEKMWGQEE------------KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Query: 669 MQGQEEKM 676
M+GQEEK+
Sbjct: 884 MRGQEEKI 891
Score = 248 bits (632), Expect = 2e-65
Identities = 150/343 (43%), Positives = 226/343 (65%), Gaps = 49/343 (14%)
Query: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 497
+K + +E +E++ E EE+ ++K QEK+ E + E + +++
Sbjct: 193 KKADRYIEELTKERDALSLELYRNTITNEEL--KKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 498 QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKM 556
++K+ E+ + L + + Q++MW+QEE++RE EKK ++QE+K W
Sbjct: 251 LKRKL--------ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW------ 296
Query: 557 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 616
R+EER+RE+E KMRE+EE M QE++++EQE+++REQE+++ EQ+E ++EQEE+M EQEE
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE-LREQEEQMQEQEE 355
Query: 617 KMWEQEEEDKMQEQEEMMW--------------EQEEKMQEQEEKMWEQEEKMREQEEKM 662
KMWEQEE KM+EQEE MW EQE+KM++QEE+MWEQ+E++RE+EE+M
Sbjct: 356 KMWEQEE--KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 413
Query: 663 REQ------------EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
REQ E+KMQ QE+K R+QEEKMQ +EE++RE+E+KMR +EE M QEEK
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMREQEEK 472
Query: 711 MWGQEEKMWGQEEMREKEERIRDQKEKM--QERLPEHEERCSE 751
M QEE MW QEE +++R+ +QKEK+ QE++ E EE+ E
Sbjct: 473 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 515
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 868 bits (2244), Expect = 0.0
Identities = 470/748 (62%), Positives = 588/748 (78%), Gaps = 53/748 (7%)
Query: 5 PHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSE 64
PHLP HPMMS++TRQ+KLAEAK++ TD+ VGT A+DTKKKKINNGTNPETTTS
Sbjct: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
Query: 65 GCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLG 124
GCHSPEDE+KASHQHQEALRRE+EAQ HTIRILTCQKTEL+ ALYYSQ A ++ E G
Sbjct: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE----G 158
Query: 125 ESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEE 184
E++DL RLH SW FAGEL++ALSAV+T KKADRYIEELTKERDALSLELYRNTIT+EE
Sbjct: 159 EARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
Query: 185 LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
LK+KNA+LQEKL+L ESEKSEIQLNVKELKRKLERAK LLPQ Q LQ E +EL+
Sbjct: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---LQAEADHLGKELQ 275
Query: 245 EQEKKIRKQ--EEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
K++ Q E ++W RL +Q QEEKM RQE++++E E++++EQE+++REQ
Sbjct: 276 SVSAKLQAQVEENELWN---RLNQQ------QEEKMWRQEEKIQEWEEKIQEQEEKIREQ 326
Query: 303 K-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
+ K+REQEE+M+ QEE MWE+EEKMR QEE MW +EE++ QE+ M E+E+KMR QEE M
Sbjct: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 386
Query: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
WE++E++RE EE+M EQEK+ EQEEK QEEE+IRE+EK+ +E+E M QEEK+++QEE
Sbjct: 387 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEK 445
Query: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE-K 480
+ EQE+K W+Q+ ++EK+ E+EK QEQEE +W QEEKI +QEE+W Q++KM QE K
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEE-MWRQEEKIHEQEEIWRQKEKMHEQEEK 504
Query: 481 MREQEDQMW-------EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533
+R+QE+++W EQEEK+R+QE+KMW QEE++ EQ+E RE EE+M EQ+K+W
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE-EEKMHEQEKIW--- 560
Query: 534 EKMREEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
EE+K QEQE K W QEEK+RE EE++ +E+K+RE+EE +EQEEKM +QEEK+RE
Sbjct: 561 ----EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
Query: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
QEEK+ EQEEK++EQEEK+ EQEE QE+E+KM EQEE M EQEEKMQEQEE MW QE
Sbjct: 617 QEEKIQEQEEKIREQEEKIREQEE--MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 653 EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712
EK+REQE+K+REQEEK++ QEE M+EQEEKM QEEKM EQEEKM+ QEEKM QEEKMW
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
Query: 713 GQEEKMWGQEEMREKEERIRDQKEKMQE 740
E+E R+R Q+EKMQE
Sbjct: 735 -------------EQEVRLRQQEEKMQE 749
Score = 804 bits (2076), Expect = 0.0
Identities = 441/762 (57%), Positives = 566/762 (74%), Gaps = 108/762 (14%)
Query: 1 MWPQPH------------------------------------LPPHPMMSEKTRQNKLAE 24
MWPQPH LP HPMMS++TRQ+KLAE
Sbjct: 3 MWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAE 62
Query: 25 AKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALR 84
AK++ TD+ VGT A+DTKKKKINNGTNPETTTS GCHSPEDE+KASHQHQEALR
Sbjct: 63 AKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALR 122
Query: 85 REIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQ 144
RE+EAQ HTIRILTCQKTEL+ ALYYSQ A ++ E GE++DL RLH SW FAGEL+
Sbjct: 123 RELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE----GEARDLISRLHDSWKFAGELE 178
Query: 145 RALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKS 204
+ALSAV+T KKADRYIEELTKERDALSLELYRNTIT+EELK+KNA+LQEKL+L ESEKS
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238
Query: 205 EIQLNVKELKRKLERAKFLLP------------------------QVQTNTL-------- 232
EIQLNVKELKRKLERAK LLP QV+ N L
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL 292
+E+MWRQEE+++E E+KI++QEEK+ QEE++REQE KMR QEE M +E+++R QE+ +
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 293 REQEKELREQKKLR-EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
E+E+++R Q+++ E+EE+M+ QEE MWE+EEK+RE EEKM ++E++ EQE++ +E+E
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM-HEQEKIREQEEKRQEEE 417
Query: 352 -----QKMRDQEERMWEQDERLREKEERMREQE-KMWEQEEKMQEEERIREREKKMREEE 405
+K ++QE +MW Q+E++RE+EE++REQE KMW QEEK+ E+E+IRE EK R+E+
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK--RQEQ 475
Query: 406 ETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQ--------EKMQEQEEKIW 456
E M QEEK+ +QEE +W Q+EK Q++++ +Q+EK+W Q EK++EQEEK+W
Sbjct: 476 EEMWRQEEKIHEQEE-IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Query: 457 EQEEKIRDQEEMWGQEKKM------WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
QEEKIR+QEEMW +E+KM W +EK +EQED+MW QEEK+R+QE+K+W QEE++
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 511 EQDERLREKEERMREQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKMREEERM-REREKK 568
EQ+E+ +E+EE KMW+QEEK+RE E+K QEQE+K +QEEK+RE+E M +E+E+K
Sbjct: 595 EQEEKRQEQEE------KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648
Query: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
M E+EE M EQEEKMQEQEE M QEEK+ EQE+K++EQEEK+ EQEE M QE+E+KM
Sbjct: 649 MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM--QEQEEKMW 706
Query: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
EQEE M EQEEKMQEQEEKM QEEKM EQE ++R+QEEKMQ
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 455 bits (1171), Expect = e-128
Identities = 270/626 (43%), Positives = 412/626 (65%), Gaps = 74/626 (11%)
Query: 166 KERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLP 225
+ ++AL EL T L + ELQ L ++ +++ ++L +L +
Sbjct: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
Query: 226 QVQ-----TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
+++ T +++ R EEL ++ + + + +E L+E+ K++E+ + +
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
++ ++ KEL+ + E+ KL ++Q+Q + + + ++ + + + + + E L
Sbjct: 236 EKSEIQLNVKELKRK----LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE-L 290
Query: 341 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
W + Q QEE+MW Q+E+++E EE+++EQE E+ ++EE+IRE+E+K
Sbjct: 291 WNRLNQQ---------QEEKMWRQEEKIQEWEEKIQEQE-----EKIREQEEKIREQEEK 336
Query: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQEQEEKIWEQE 459
MR +EE M E+EEKM++QEE MWE+EEK + Q+E +WE +EKM+ QEE +WE+E
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEK------MRRQEEMMWEKEEKMRRQEEMMWEKE 390
Query: 460 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
EKIR+ EE KM QEK+REQE++ ++EEK+R+QE++ +QE +MW Q+E++RE+
Sbjct: 391 EKIRELEE------KMHEQEKIREQEEKR-QEEEKIREQEKRQ-EQEAKMWRQEEKIREQ 442
Query: 520 EERMREQ-KKMWQQEEKMREEKKTQEQEKKT-----WDQEEKM-------REEERMRERE 566
EE++REQ KKMW+QEEK+ E++K +E+EK+ W QEEK+ R++E+M E+E
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502
Query: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE---E 623
+K+R++EE + QEEK++EQEEK+REQEEKMW QEEK++EQEE MW +EEKM EQE E
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWREEEKMHEQEKIWE 561
Query: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
E+K QEQE+ MW QEEK++EQEEK+W QEEK+REQEEK +EQEEKM QEEK+REQEEK+
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Query: 684 QGQEEKMREQEEKMR--------------GQEEKMWGQEEKMWGQEEKMWGQEE-MREKE 728
Q QEEK+REQEEK+R QEEKM QEEKM QEE MW QEE +RE+E
Sbjct: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
Query: 729 ERIRDQKEKMQER---LPEHEERCSE 751
++IR+Q+EK++E+ + E EE+ E
Sbjct: 682 KKIREQEEKIREQEEMMQEQEEKMWE 707
Score = 387 bits (994), Expect = e-107
Identities = 235/570 (41%), Positives = 373/570 (65%), Gaps = 44/570 (7%)
Query: 200 ESEKSEIQLNVKELKRKLERAKFLLPQV--QTNTLQEEMWRQEEELREQEKKIRKQEEKM 257
E E+ + + L+R+LE + + Q LQ ++ + +++ E + R ++
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 258 ---WRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR-EQEKELREQKKLREQEEQMQ 313
W+ L + + Q++K R + L ++ L E + ++L+E+ ++Q
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
E+ + + ++ +++ +++ R+ ER ++ +Q+++ + + + ++ + + K +
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEADHLGKELQSVSAKLQ 282
Query: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 433
E+ ++W + + QEE+ R+ E+K++E EE ++EQEEK+++QEE + EQEEK
Sbjct: 283 AQVEENELWNRLNQQQEEKMWRQ-EEKIQEWEEKIQEQEEKIREQEEKIREQEEK----- 336
Query: 434 RLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW-RQEKMREQEDQMWEQ 491
+ Q+E +WE +EKM+ QEE +WE+EEK+R QEEM MW ++EKMR QE+ MWE+
Sbjct: 337 -MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM------MWEKEEKMRRQEEMMWEK 389
Query: 492 EEKMRDQEQKMWDQE-----ERMWEQDERLREKEERMREQKKMWQQEEKMRE-EKKTQEQ 545
EEK+R+ E+KM +QE E +++E++RE+E+R ++ KMW+QEEK+RE E+K +EQ
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ 605
EKK W QEEK+ E+E++RE EK R+E+E M QEEK+ EQEE R Q+EKM EQEEK++
Sbjct: 450 EKKMWRQEEKIHEQEKIREEEK--RQEQEEMWRQEEKIHEQEEIWR-QKEKMHEQEEKIR 506
Query: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
+QEEK+W QEEK+ EQEE K++EQEE MW QEEK++EQEE MW +EEKM EQE+ +
Sbjct: 507 KQEEKVWRQEEKIREQEE--KIREQEEKMWRQEEKIREQEE-MWREEEKMHEQEKIW--E 561
Query: 666 EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE-M 724
EEK Q QE+KM QEEK++ QEEK+ QEEK+R QEEK QEEKMW QEEK+ QEE +
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Query: 725 REKEERIRDQKEKMQER---LPEHEERCSE 751
+E+EE+IR+Q+EK++E+ E EE+ E
Sbjct: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 789 bits (2037), Expect = 0.0
Identities = 417/670 (62%), Positives = 531/670 (79%), Gaps = 51/670 (7%)
Query: 5 PHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSE 64
PHLP HPMMS++TRQ+KLAEAK++ TD+ VGT A+DTKKKKINNGTNPETTTS
Sbjct: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
Query: 65 GCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLG 124
GCHSPEDE+KASHQHQEALRRE+EAQ HTIRILTCQKTEL+ ALYYSQ A ++ E G
Sbjct: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE----G 158
Query: 125 ESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEE 184
E++DL RLH SW FAGEL++ALSAV+T KKADRYIEELTKERDALSLELYRNTIT+EE
Sbjct: 159 EARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
Query: 185 LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
LK+KNA+LQEKL+L ESEKSEIQLNVKELKRKLERAK LLPQ Q LQ E +EL+
Sbjct: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---LQAEADHLGKELQ 275
Query: 245 EQEKKIRKQ--EEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
K++ Q E ++W RL +Q QEEKM RQE++++E E++++EQE+++REQ
Sbjct: 276 SVSAKLQAQVEENELWN---RLNQQ------QEEKMWRQEEKIQEWEEKIQEQEEKIREQ 326
Query: 303 K-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
+ K+REQEE+M+ QEE MWE+EEKMR QEE MW E+E+KMR EE M
Sbjct: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW--------------EKEEKMRRLEEMM 372
Query: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
WE++E++RE EE+M EQEK+ EQEEK QEEE+IRE+EK+ +E+E M QEEK+++QEE
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEK 431
Query: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
+ EQE+K W+Q+ ++EK+ E+EK QEQEE +W QEEKIR+QEE+W Q++KM QEK+
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEE-MWRQEEKIREQEEIWRQKEKMHEQEKI 490
Query: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE-EK 540
R+QE+++W QEEKM DQE+K+ +QEE+MW Q+E++RE+EE++REQ EEK+RE E+
Sbjct: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ------EEKIREQEE 544
Query: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
QEQE+K +QEEKM+E+E+MR +E+K+RE+EE +REQ+EK++EQEEK+ EQEEK+ EQ
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ 604
Query: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 660
EE MQEQEEKMWEQEEKM EQEE+ M EQEEKM+ QEEKMWEQE ++R+QEE
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEK---------MQEQEEKMRRQEEKMWEQEVRLRQQEE 655
Query: 661 KMREQEEKMQ 670
KM+E +E ++
Sbjct: 656 KMQEHQEHLE 665
Score = 653 bits (1685), Expect = 0.0
Identities = 366/685 (53%), Positives = 478/685 (69%), Gaps = 136/685 (19%)
Query: 1 MWPQPH------------------------------------LPPHPMMSEKTRQNKLAE 24
MWPQPH LP HPMMS++TRQ+KLAE
Sbjct: 3 MWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAE 62
Query: 25 AKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALR 84
AK++ TD+ VGT A+DTKKKKINNGTNPETTTS GCHSPEDE+KASHQHQEALR
Sbjct: 63 AKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALR 122
Query: 85 REIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQ 144
RE+EAQ HTIRILTCQKTEL+ ALYYSQ A ++ E GE++DL RLH SW FAGEL+
Sbjct: 123 RELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE----GEARDLISRLHDSWKFAGELE 178
Query: 145 RALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKS 204
+ALSAV+T KKADRYIEELTKERDALSLELYRNTIT+EELK+KNA+LQEKL+L ESEKS
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238
Query: 205 EIQLNVKELKRKLERAKFLLP------------------------QVQTNTL-------- 232
EIQLNVKELKRKLERAK LLP QV+ N L
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 233 QEEMWR---------------------QEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
+E+MWR QEE++REQE+K+R+QEE MW +EE++R QE M
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE------------EQMQEQEEKM 319
E+EEKMRR E+ + E+E+++RE E+++ EQ+K+REQE E+ QEQE KM
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418
Query: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
W QEEK+REQEEK+ QE+++W QE+++ EQE K+R++E+R EQ+E R+ EE++REQE
Sbjct: 419 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQE-KIREEEKRQ-EQEEMWRQ-EEKIREQE 475
Query: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQ 438
++W Q+EKM E+E+IR++E+K+ +EE M +QEEK+++QEE MW QEEK Q++++ EQ
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Query: 439 KEKLWEQEK-MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ--------EKMREQEDQMW 489
+EK+ EQE+ MQEQEEK+ EQEEK+++QE+M QE+K+ Q EK+REQE+++W
Sbjct: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 595
Query: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
EQEEK+R+QE+ M +QEE+MWEQ+E++ E+EE+M+E QEEKMR QE+K
Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE------QEEKMR------RQEEKM 643
Query: 550 WDQEEKMREEERMREREKKMREEEE 574
W+Q E R+R++E+KM+E +E
Sbjct: 644 WEQ------EVRLRQQEEKMQEHQE 662
Score = 427 bits (1099), Expect = e-119
Identities = 266/586 (45%), Positives = 396/586 (67%), Gaps = 57/586 (9%)
Query: 182 NEELKKKNAELQ-EKLRLAESEKSEIQLNV---KELKRKLE-RAKFLLPQVQTNTLQEEM 236
++E ++ E Q +R+ +K+E+Q+ + + ++LE A+ L+ ++ +
Sbjct: 117 HQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH------DS 170
Query: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296
W+ EL + + Q++K R E L ++ + + + ++ L+E+ +L+E+
Sbjct: 171 WKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKL 230
Query: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
+ + +K E Q+ +E K + K+ ++++ + + L ++ + + + Q +
Sbjct: 231 QLVESEKS----EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
Query: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQE-EERIREREKKMREEEETMREQEEKM 415
+ E +W RL +++E EKMW QEEK+QE EE+I+E+E+K+RE+EE +REQEEKM
Sbjct: 287 ENE-LWN---RLNQQQE-----EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
++QEE MWE+EEK + Q+E +WE +EKM+ EE +WE+EEKIR+ EE K
Sbjct: 338 RRQEEMMWEKEEK------MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE------K 385
Query: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQQE 533
M QEK+REQE++ ++EEK+R+QE++ +QE +MW Q+E++RE+EE++REQ KKMW+QE
Sbjct: 386 MHEQEKIREQEEKR-QEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIREQEKKMWRQE 443
Query: 534 EKMREEKKTQEQEKKT-----WDQEEKMREEERM-REREK-----KMREEEEMMREQEEK 582
EK+ E++K +E+EK+ W QEEK+RE+E + R++EK K+R++EE + QEEK
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
M +QEEK+REQEEKMW QEEK++EQEEK+ EQEEK+ EQEE MQEQEE M EQEEKMQ
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE--MMQEQEEKMGEQEEKMQ 561
Query: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
EQE KM QEEK+REQEEK+REQ+EK++ QEEK+ EQEEK++ QEE M+EQEEKM QEE
Sbjct: 562 EQE-KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 703 KMWGQEEKMWGQEEKMWGQEE-MREKEERIRDQKEKMQERLPEHEE 747
KM QEEKM QEEKM QEE M E+E R+R Q+EKMQE EH E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH-QEHLE 665
Score = 375 bits (962), Expect = e-103
Identities = 239/553 (43%), Positives = 344/553 (62%), Gaps = 77/553 (13%)
Query: 273 EQEEKMRRQEKRLREQEKELRE------QEKELREQ--------KKLREQEEQMQEQEEK 318
EQ+ + QE RE E ++ Q+ EL+ K+L + + +
Sbjct: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
Query: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
W+ ++ + + Q+++ +++ ++ + + R DE L+EK +++E+
Sbjct: 170 SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK 229
Query: 379 EKMWEQEEK-----MQEEERIREREKKMREEEETMREQE---EKMQKQEENMWEQ-EEKE 429
++ E E+ ++E +R ER K + +++ E + +++Q + Q EE E
Sbjct: 230 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 289
Query: 430 WQQQRLPEQKEKLWEQE-KMQEQEEKIWEQEEKIRDQEE-MWGQEKKMWRQ--------E 479
+ +Q+EK+W QE K+QE EEKI EQEEKIR+QEE + QE+KM RQ E
Sbjct: 290 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349
Query: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWE-------------------QDERLREKE 520
KMR QE+ MWE+EEKMR E+ MW++EE++ E ++E++RE+E
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 409
Query: 521 ERMREQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
+R ++ KMW+QEEK+RE E+K +EQEKK W QEEK+ E+E++RE EK R+E+E M Q
Sbjct: 410 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK--RQEQEEMWRQ 467
Query: 580 EEKMQEQE------------EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE---- 623
EEK++EQE EK+R+QEEK+W QEEKM +QEEK+ EQEEKMW QEE
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 624 -EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEK 682
E+K++EQEE + EQEE MQEQEEKM EQEEKM+EQ EKMR QEEK++ QEEK+REQ+EK
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEKIREQKEK 586
Query: 683 MQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE-MREKEERIRDQKEKMQE- 740
++ QEEK+ EQEEK+R QEE M QEEKMW QEEKM QEE M+E+EE++R Q+EKM E
Sbjct: 587 IREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646
Query: 741 --RLPEHEERCSE 751
RL + EE+ E
Sbjct: 647 EVRLRQQEEKMQE 659
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 689 bits (1778), Expect = 0.0
Identities = 379/665 (56%), Positives = 489/665 (73%), Gaps = 91/665 (13%)
Query: 1 MWPQPHLPPHP------------MMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTK 48
MWPQPHLP HP MMS++TRQ+KLAEAK++ TD+ VGT A+DTK
Sbjct: 88 MWPQPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTK 147
Query: 49 KKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETAL 108
KKKINNGTNPETTTS GCHSPEDE+KASHQHQEALRRE+EAQ HTIRILTCQKTEL+ AL
Sbjct: 148 KKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMAL 207
Query: 109 YYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKER 168
YYSQ A ++ E GE++DL RLH SW FAGEL++ALSAV+T KKADRYIEELTKER
Sbjct: 208 YYSQHAVKQLE----GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKER 263
Query: 169 DALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQ 228
DALSLELYRNTIT+EELK+KNA+LQEKL+L ESEKSEIQLNVKELKRKLERAK LLPQ Q
Sbjct: 264 DALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ 323
Query: 229 TNT--------LQEEMWRQEEELREQE---KKIRKQEEKMWRQEERLREQEGKMREQEEK 277
LQ + + ++ E E + ++QEEKMWRQEE+++E E K++EQEEK
Sbjct: 324 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383
Query: 278 MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
+R QE+++REQE+++R QE+ + E+EE+M+ QEE MWE+EEKMR QEE MW +E
Sbjct: 384 IREQEEKIREQEEKMRRQEE------MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437
Query: 338 ERLWEQEKQMREQE------------------QKMRDQEERMWEQDERLREKEERMREQE 379
E++ E E++M EQE +K ++QE +MW Q+E++RE+EE++REQE
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497
Query: 380 -KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPE 437
KMW QEEK+ E+E+IRE EK R+E+E M QEEK+++QEE +W Q+EK Q++++ +
Sbjct: 498 EKMWRQEEKIHEQEKIREEEK--RQEQEEMWRQEEKIREQEE-IWRQKEKIHEQEEKIRK 554
Query: 438 QKEKLWEQE--------KMQEQEEKIW-------EQEEKIRDQEEMWGQEKKMWRQEKMR 482
Q+EK+W QE K++EQEEK+W EQEEKIR+QE EK+R
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE------------EKIR 602
Query: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQQEEKMRE-EK 540
EQE+ EQEEKM +QE+KM +QEE+M EQ+E++R +EE++REQ KK+ +QEEK+RE E+
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
QEQE+K W+QEEKM E+ E+KM+E+EE MR QEEKM EQE ++R+QEEKM E
Sbjct: 663 MMQEQEEKMWEQEEKMCEQ------EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 716
Query: 601 EEKMQ 605
+E ++
Sbjct: 717 QEHLE 721
Score = 436 bits (1120), Expect = e-122
Identities = 265/586 (45%), Positives = 393/586 (67%), Gaps = 62/586 (10%)
Query: 182 NEELKKKNAELQ-EKLRLAESEKSEIQLNV---KELKRKLE-RAKFLLPQVQTNTLQEEM 236
++E ++ E Q +R+ +K+E+Q+ + + ++LE A+ L+ ++ +
Sbjct: 178 HQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH------DS 231
Query: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296
W+ EL + + Q++K R E L ++ + + + ++ L+E+ +L+E+
Sbjct: 232 WKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKL 291
Query: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
+ + +K E Q+ +E K + K+ ++++ + + L ++ + + + Q +
Sbjct: 292 QLVESEKS----EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 347
Query: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQE-EERIREREKKMREEEETMREQEEKM 415
+ E +W RL +++E EKMW QEEK+QE EE+I+E+E+K+RE+EE +REQEEKM
Sbjct: 348 ENE-LWN---RLNQQQE-----EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
++QEE MWE+EEK + Q+E +WE +EKM+ QEE +WE+EEKIR+ EE K
Sbjct: 399 RRQEEMMWEKEEK------MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE------K 446
Query: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK-KMWQQE 533
M QEK+REQE++ ++EEK+R+QE++ +QE +MW Q+E++RE+EE++REQ+ KMW+QE
Sbjct: 447 MHEQEKIREQEEKR-QEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIREQEEKMWRQE 504
Query: 534 EKMREEKKTQEQEKK-----TWDQEEKMREE-------ERMREREKKMREEEEMMREQEE 581
EK+ E++K +E+EK+ W QEEK+RE+ E++ E+E+K+R++EE M QEE
Sbjct: 505 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 582 KMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM 641
KM +QEEK+REQEEK+W QEEK++EQEEK+ EQEEK+ EQEE QEQEE M EQEEKM
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE--MTQEQEEKMGEQEEKM 622
Query: 642 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
EQEEKM EQEEKMR QEEK+REQE+K++ QEEK+REQEE MQ QEEKM EQEEKM QE
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682
Query: 702 EKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
EKM QEEKM QEEKMW E+E R+R Q+EKMQE EH E
Sbjct: 683 EKMQEQEEKMRRQEEKMW------EQEVRLRQQEEKMQEH-QEHLE 721
Score = 382 bits (981), Expect = e-106
Identities = 241/552 (43%), Positives = 339/552 (61%), Gaps = 80/552 (14%)
Query: 273 EQEEKMRRQEKRLREQEKELRE------QEKELREQ--------KKLREQEEQMQEQEEK 318
EQ+ + QE RE E ++ Q+ EL+ K+L + + +
Sbjct: 171 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 230
Query: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
W+ ++ + + Q+++ +++ ++ + + R DE L+EK +++E+
Sbjct: 231 SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK 290
Query: 379 EKMWEQEEK-----MQEEERIREREKKMREEEETMREQE---EKMQKQEENMWEQ-EEKE 429
++ E E+ ++E +R ER K + +++ E + +++Q + Q EE E
Sbjct: 291 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 350
Query: 430 WQQQRLPEQKEKLWEQE-KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488
+ +Q+EK+W QE K+QE EEKI EQEEKIR+QEE K ++EKMR QE+ M
Sbjct: 351 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE-----KIREQEEKMRRQEEMM 405
Query: 489 WEQEEKMRDQEQKMWD-------QEERMWEQDERLREKEERMREQK-------------- 527
WE+EEKMR QE+ MW+ QEE MWE++E++RE EE+M EQ+
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 465
Query: 528 ------------KMWQQEEKMRE-EKKTQEQEKKTWDQEEKMREEERMREREKKMREE-- 572
KMW+QEEK+RE E+K +EQE+K W QEEK+ E+E++RE EK+ +E
Sbjct: 466 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM 525
Query: 573 ---EEMMREQE------EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
EE +REQE EK+ EQEEK+R+QEEKMW QEEKM +QEEK+ EQEEK+W QEE
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
K++EQEE + EQEEK++EQEE EQEEKM EQEEKM EQEEKMQ QEEKMR QEEK+
Sbjct: 586 --KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE-MREKEERIRDQKEKMQE-- 740
+ QE+K+REQEEK+R QEE M QEEKMW QEEKM QEE M+E+EE++R Q+EKM E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Query: 741 -RLPEHEERCSE 751
RL + EE+ E
Sbjct: 704 VRLRQQEEKMQE 715
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 635 bits (1639), Expect = 0.0
Identities = 365/607 (60%), Positives = 449/607 (73%), Gaps = 80/607 (13%)
Query: 5 PHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSE 64
PHLP HPMMS++TRQ+KLAEAK++ TD+ VGT A+DTKKKKINNGTNPETTTS
Sbjct: 31 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 90
Query: 65 GCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLG 124
GCHSPEDE+KASHQHQEALRRE+EAQ TIRILTCQKTEL+ ALYYSQ A ++ E G
Sbjct: 91 GCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLE----G 146
Query: 125 ESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEE 184
E++DL RLH SW FAGEL++ALSAV+T KKADRYIEELTKERDALSLELYRNTIT+EE
Sbjct: 147 EARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 206
Query: 185 LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
LK+KNA+LQEKL+L ESEKSEIQLNVKELKRKLERAK LLPQ Q LQ E +EL+
Sbjct: 207 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---LQAEADHLGKELQ 263
Query: 245 EQEKKIRKQ--EEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
K++ Q E ++W RL +Q QEEKM RQE
Sbjct: 264 SVSAKLQAQVEENELWN---RLNQQ------QEEKMWRQE-------------------- 294
Query: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362
E++QE+EEK+ EQEEK+REQEEKM RQEE +WE+E +KMR QEE MW
Sbjct: 295 -------EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE-------EKMRRQEEMMW 340
Query: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE------EETMREQEEKMQ 416
E++E++RE EE+M EQEK+ EQEEK QEEE+IRE+EK+ +E EE +REQEEK++
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 417 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEK-MQEQEEKIWEQEEKIRDQEE-MWGQEKK 474
+QEE M EQEEK + EQ+EK+WEQE+ MQEQEEK+ QEEKIR+QE+ + QE+K
Sbjct: 401 EQEEMMQEQEEK------MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Query: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQQE 533
+ EQE+ M EQEEKM +QE KM +QE +M EQ+E++R +EE++REQ KK+ +QE
Sbjct: 455 IR------EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 534 EKMRE-EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
EK+RE E+ QEQE+K W+QEEKM E+ E+KM+E+EE MR QEEKM+EQE ++R+
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEEKMCEQ------EEKMQEQEEKMRRQEEKMREQEVRLRQ 562
Query: 593 QEEKMWE 599
QEEKM E
Sbjct: 563 QEEKMQE 569
Score = 632 bits (1629), Expect = 0.0
Identities = 350/596 (58%), Positives = 445/596 (74%), Gaps = 87/596 (14%)
Query: 1 MWPQPH------------------------LPPHPMMSEKTRQNKLAEAKKKFTDYRQWN 36
MWPQPH LP HPMMS++TRQ+KLAEAK++ TD+
Sbjct: 3 MWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQT 62
Query: 37 IAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRI 96
VGT A+DTKKKKINNGTNPETTTS GCHSPEDE+KASHQHQEALRRE+EAQ TIRI
Sbjct: 63 NPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRI 122
Query: 97 LTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKK 156
LTCQKTEL+ ALYYSQ A ++ E GE++DL RLH SW FAGEL++ALSAV+T KK
Sbjct: 123 LTCQKTELQMALYYSQHAVKQLE----GEARDLISRLHDSWKFAGELEQALSAVATQKKK 178
Query: 157 ADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRK 216
ADRYIEELTKERDALSLELYRNTIT+EELK+KNA+LQEKL+L ESEKSEIQLNVKELKRK
Sbjct: 179 ADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK 238
Query: 217 LERAKFLLP------------------------QVQTNTL--------QEEMWRQEEELR 244
LERAK LLP QV+ N L +E+MWRQEE+++
Sbjct: 239 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 298
Query: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
E+E+KI++QEEK+ QEE++R QE M E+EEKMRRQE+ + E+E+++RE E+++ EQ+K
Sbjct: 299 EREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 358
Query: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
+REQEE+ QE EEK+ EQ EK +EQE KMWRQEE++ EQE+++REQE+ M++QEE+M EQ
Sbjct: 359 IREQEEKRQE-EEKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 365 DERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 424
+E++ E+EE M+EQE E+ ++EE+IRE+EKK+RE+EE +REQEE MQ+QEE M E
Sbjct: 417 EEKMWEQEEEMQEQE-----EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE 471
Query: 425 QEEKEWQQQ-RLPEQKEKLWEQ-EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
QE K +Q+ ++ EQ+EK+ Q EK++EQE+KI EQEEKIR+QEEM M+
Sbjct: 472 QEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM------------MQ 519
Query: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
EQE++MWEQEEKM +QE+KM +QEE+M Q+E++RE+E R+R QQEEKM+E
Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLR------QQEEKMQE 569
Score = 370 bits (949), Expect = e-102
Identities = 219/487 (44%), Positives = 328/487 (67%), Gaps = 25/487 (5%)
Query: 266 EQEGKMREQEEKMRRQEKRLREQE-KELREQEKELREQ--------KKLREQEEQMQEQE 316
E E K Q ++ R+E + Q + L Q+ EL+ K+L + + +
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 317 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
W+ ++ + + Q+++ +++ ++ + + R DE L+EK +++
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 215
Query: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
E+ ++ E E+ E ++ +E K + E + ++++Q + +++ ++ + + +
Sbjct: 216 EKLQLVESEKS---EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 272
Query: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE-MWGQEKKMWRQ-EKMREQEDQMWEQEEK 494
++ +LW + Q+QEEK+W QEEKI+++EE + QE+K+ Q EKMR QE+ MWE+EEK
Sbjct: 273 VEENELWNRLN-QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331
Query: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
MR QE+ MW++EE++ E +E++ E +E++REQ++ Q+EEK+RE++K QEQE K W
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEKRQEQEAKMW---- 386
Query: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
R+EE++RE+E+K+RE+EEMM+EQEEKM EQEEKM EQEE+M EQEEKM+ QEEK+ EQ
Sbjct: 387 --RQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
E+K+ EQEE K++EQEEMM EQEEKM EQE KM EQE KM+EQEEKMR QEEK++ QE+
Sbjct: 445 EKKIREQEE--KIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502
Query: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE-MREKEERIRD 733
K+REQEEK++ QEE M+EQEEKM QEEKM QEEKM QEEKM QEE MRE+E R+R
Sbjct: 503 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQ 562
Query: 734 QKEKMQE 740
Q+EKMQE
Sbjct: 563 QEEKMQE 569
Score = 364 bits (934), Expect = e-100
Identities = 220/512 (42%), Positives = 332/512 (64%), Gaps = 54/512 (10%)
Query: 166 KERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLP 225
+ ++AL EL T L + ELQ L ++ +++ ++L +L +
Sbjct: 104 QHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 163
Query: 226 QVQ-----TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
+++ T +++ R EEL ++ + + + +E L+E+ K++E+ + +
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 223
Query: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
++ ++ KEL+ + E+ KL ++Q+Q + + + ++ + + + + + E L
Sbjct: 224 EKSEIQLNVKELKRK----LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE-L 278
Query: 341 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
W + Q QEE+MW Q+E+++E+EE+++EQE E+IRE+E+K
Sbjct: 279 WNRLNQQ---------QEEKMWRQEEKIQEREEKIQEQE------------EKIREQEEK 317
Query: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
MR +EE M E+EEKM++QEE MWE+EEK + E +EK+ EQEK++EQEEK ++EE
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEK------IRELEEKMHEQEKIREQEEKR-QEEE 370
Query: 461 KIRDQEEMWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
KIR+QE+ QE KMWRQE K+REQE+++ EQEE M++QE+KM +QEE+MWEQ+E ++E+
Sbjct: 371 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQ 430
Query: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMRE 578
EE+MR R+E+K +EQEKK +QEEK+RE EE M+E+E+KM E+E M E
Sbjct: 431 EEKMR------------RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638
QE KMQEQEEKMR QEEK+ EQE+K++EQEEK+ EQEE M QE+E+KM EQEE M EQE
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM--QEQEEKMWEQEEKMCEQE 536
Query: 639 EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
EKMQEQEEKM QEEKMREQE ++R+QEEKMQ
Sbjct: 537 EKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 341 bits (874), Expect = 2e-93
Identities = 205/493 (41%), Positives = 323/493 (65%), Gaps = 33/493 (6%)
Query: 200 ESEKSEIQLNVKELKRKLERA--KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 257
E E+ + + L+R+LE + Q LQ ++ + +++ E + R ++
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 258 ---WRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR-EQEKELREQKKLREQEEQMQ 313
W+ L + + Q++K R + L ++ L E + ++L+E+ ++Q
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 215
Query: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
E+ + + ++ +++ +++ R+ ER ++ +Q+++ + + + ++ + + K +
Sbjct: 216 EKLQLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEADHLGKELQSVSAKLQ 270
Query: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ-Q 432
E+ ++W + + QEE+ R+ E+K++E EE ++EQEEK+++QEE M QEE W+ +
Sbjct: 271 AQVEENELWNRLNQQQEEKMWRQ-EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE 329
Query: 433 QRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 491
+++ Q+E +WE +EK++E EEK+ EQE KIR+QEE +E+K+ QEK +EQE +MW Q
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388
Query: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD 551
EEK+R+QE+K+ +QEE M EQ+E++ E+EE KMW+QEE+M QEQE+K
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEE------KMWEQEEEM------QEQEEKMRR 436
Query: 552 QEEKMREEER-MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
QEEK+RE+E+ +RE+E+K+RE+EEMM+EQEEKM EQE KM EQE KM EQEEKM+ QEEK
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Query: 611 MWEQEEKMWEQEE-----EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
+ EQE+K+ EQEE E+ MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKMREQ
Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQ 556
Query: 666 EEKMQGQEEKMRE 678
E +++ QEEKM+E
Sbjct: 557 EVRLRQQEEKMQE 569
Score = 286 bits (731), Expect = 7e-77
Identities = 188/463 (40%), Positives = 295/463 (63%), Gaps = 45/463 (9%)
Query: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
EQK + +E ++ + E + + Q+ ++ + L+ + +++ E + RD R
Sbjct: 98 EQKASHQHQEALRRELEAQVQTIRILTCQKTEL---QMALYYSQHAVKQLEGEARDLISR 154
Query: 361 M---WEQDERLREKEERMREQEKMWEQ--EEKMQEEERIREREKKMREEEETMREQEEKM 415
+ W+ L + + Q+K ++ EE +E + + + +E ++E+ K+
Sbjct: 155 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 214
Query: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE-KK 474
Q++ + + + EK Q + E K KL + K+ +++++ + + G+E +
Sbjct: 215 QEKLQLV--ESEKSEIQLNVKELKRKL--------ERAKLLLPQQQLQAEADHLGKELQS 264
Query: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534
+ + + + +E+++W + + QEE+MW Q+E+++E+EE+++EQ EE
Sbjct: 265 VSAKLQAQVEENELWNRLNQQ---------QEEKMWRQEEKIQEREEKIQEQ------EE 309
Query: 535 KMRE-EKKTQEQEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
K+RE E+K + QE+ W++EEKMR +EE M E+E+K+RE EE M EQE K++EQEEK R+
Sbjct: 310 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEK-RQ 367
Query: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
+EEK+ EQE K QEQE KMW QEEK+ EQEE K++EQEEMM EQEEKM EQEEKMWEQE
Sbjct: 368 EEEKIREQE-KRQEQEAKMWRQEEKIREQEE--KIREQEEMMQEQEEKMGEQEEKMWEQE 424
Query: 653 EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712
E+M+EQEEKMR QEEK++ QE+K+REQEEK++ QEE M+EQEEKM QE KM QE KM
Sbjct: 425 EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQ 484
Query: 713 GQEEKMWGQEE-MREKEERIRDQKEKMQER---LPEHEERCSE 751
QEEKM QEE +RE+E++IR+Q+EK++E+ + E EE+ E
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527
Score = 231 bits (588), Expect = 3e-60
Identities = 149/420 (35%), Positives = 241/420 (57%), Gaps = 41/420 (9%)
Query: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETM 408
E EQK Q + ++ + + R+ +K Q + +++ E + R+ +
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
+ + + E+ + ++ + R E+ K + ++ I ++E K
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELK------- 208
Query: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKK 528
EK QEK++ E + E + +++ ++K+ E+ + L +++ E
Sbjct: 209 ---EKNAKLQEKLQLVESEKSEIQLNVKELKRKL--------ERAKLLLPQQQLQAEADH 257
Query: 529 MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 588
+ ++ + + + + Q +E + W++ + ++EE+M +E+K++E EE ++EQEEK++EQEE
Sbjct: 258 LGKELQSVSAKLQAQVEENELWNRLNQ-QQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316
Query: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE----EDKMQEQEEMMWEQE-----E 639
KMR QEE MWE+EEKM+ QEE MWE+EEK+ E EE ++K++EQEE E+E E
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Query: 640 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG 699
K QEQE KMW QEEK+REQEEK+REQEE MQ QEEKM EQEEKM QEE+M+EQEEKMR
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 700 QEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKV 759
QEEK+ QE+K+ RE+EE+IR+Q+E MQE+ + E+ + C +K+
Sbjct: 437 QEEKIREQEKKI-------------REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483
>gi|239750781 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 307
Score = 426 bits (1094), Expect = e-119
Identities = 223/265 (84%), Positives = 224/265 (84%), Gaps = 38/265 (14%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGT ATDTKKKKIN+GTNPET
Sbjct: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPET 60
Query: 61 TTSEGCHSPED----------EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYY 110
TTS GCHSPED EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYY
Sbjct: 61 TTSGGCHSPEDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYY 120
Query: 111 SQDAARKFEDGNL----------------------------GESKDLAGRLHHSWHFAGE 142
SQDAARKFEDGNL GESKDLAGRLHHSWHFAGE
Sbjct: 121 SQDAARKFEDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGE 180
Query: 143 LQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESE 202
LQRALSAVST HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESE
Sbjct: 181 LQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESE 240
Query: 203 KSEIQLNVKELKRKLERAKFLLPQV 227
KSEIQLNVKELKRKLERAKFLLPQV
Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQV 265
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 424 bits (1091), Expect = e-118
Identities = 250/524 (47%), Positives = 369/524 (70%), Gaps = 92/524 (17%)
Query: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239
ITNEELK+KNAELQE+L+L E+EKSEIQL++KELKRKLE K LPQ
Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ------------- 50
Query: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
E ++REQEG++REQE ++R QE ++REQE ++REQE ++
Sbjct: 51 ---------------------EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 89
Query: 300 REQK-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
REQ+ ++REQE Q++EQE ++ EQE ++REQE ++ QE ++ EQE Q+REQE ++R+QE
Sbjct: 90 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 149
Query: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
++ EQ+ ++RE+E ++REQE ++RE+E ++RE+E +REQE +M +Q
Sbjct: 150 GQVREQEGQVREQEGQVREQEG------------QVREQEGQVREQEGQVREQEGQMGEQ 197
Query: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
E M EQEE+ +Q+ E+MQ+QEE++ EQEE++R
Sbjct: 198 EGQMGEQEEQMGEQE------------EQMQKQEEQMGEQEEQMRK-------------- 231
Query: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
QE+QM EQEE+++ QE+++ QEE+M +Q+E++RE+EE+MRE QEE+M +
Sbjct: 232 -----QEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE------QEEQMLK 280
Query: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW 598
+K+ EQE++T +QEE+MRE+ E++MRE+EE MREQEE+M+EQEE+M +QEE+MW
Sbjct: 281 QKEQTEQEEQTGEQEEQMREQ------EEQMREQEEQMREQEEQMREQEEQMGKQEEQMW 334
Query: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658
EQ+E+M EQ+E+MW+QEE+M EQEE+ MQ+QEE + +QEE+M++QEE+M +QEE+MR+Q
Sbjct: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQ--MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
Query: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
EE+M EQ+E+M Q+E+MREQEE+M Q+E+MR+QEE M Q+E
Sbjct: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 332 bits (850), Expect = 1e-90
Identities = 212/475 (44%), Positives = 342/475 (72%), Gaps = 53/475 (11%)
Query: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345
R +EL+E+ EL+E+ +L E E+ E + ++E + K+ + L QE
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKS---------EIQLHIKELKRKLETDKIPL-PQEG 52
Query: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQE-KMWEQEEKMQEEE-RIREREKKMRE 403
Q+REQE ++R+QE ++ EQ+ ++RE+E ++REQE ++ EQE +++E+E ++RE+E ++RE
Sbjct: 53 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 112
Query: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIWEQEEKI 462
+E +REQE ++++QE + EQE + + EQ+ ++ EQE +++EQE ++ EQE ++
Sbjct: 113 QEGQVREQEGQVREQEGQVREQEGQ------VREQEGQVREQEGQVREQEGQVREQEGQV 166
Query: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
R+QE GQ +REQE Q+ EQE ++R+QE +M +QE +M EQ+E++ E+EE+
Sbjct: 167 REQE---GQ---------VREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ 214
Query: 523 MREQKK-MWQQEEKMREEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQE 580
M++Q++ M +QEE+MR+ QEE+M E EE+++++E++++++EE MR+QE
Sbjct: 215 MQKQEEQMGEQEEQMRK-------------QEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
E+M+EQEE+MREQEE+M +Q+E+ EQEE+ EQEE+M EQEE+ M+EQEE M EQEE+
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQEEQ--MREQEEQMREQEEQ 318
Query: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
M+EQEE+M +QEE+M EQ+E+M EQ+E+M QEE+M EQEE+MQ QEE++R+QEE+MR Q
Sbjct: 319 MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378
Query: 701 EEKMWGQEEKMWGQEEKMWGQ-EEMREKEERIRDQKEKM---QERLPEHEERCSE 751
EE+M QEE+M QEE+M Q E+M E++E++R+Q+E+M +E++ + EE E
Sbjct: 379 EEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
Score = 242 bits (617), Expect = 1e-63
Identities = 153/381 (40%), Positives = 242/381 (63%), Gaps = 67/381 (17%)
Query: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
+P + +++ + QEE + EK Q + ++K+ + QE Q+ EQE +
Sbjct: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
Query: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQK-KMWQQEEKMRE-EKKTQEQEKKTWDQ 552
+R+QE ++ +QE ++ EQ+ ++RE+E ++REQ+ ++ +QE ++RE E + +EQE + +Q
Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
Query: 553 EEKMREEE-------------------------------------------RMREREKKM 569
E ++RE+E ++RE+E ++
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
Query: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE-----E 624
RE+E +REQE +M EQE +M EQEE+M EQEE+MQ+QEE+M EQEE+M +QEE E
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM-------------REQEEKMQG 671
+++Q+QEE + +QEE+M++QEE+M EQEE+MREQEE+M EQEE+M+
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 672 QEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE-MREKEER 730
QEE+MREQEE+M+ QEE+MREQEE+M QEE+MW Q+E+MW Q+E+MW QEE M E+EE+
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 731 IRDQKE---KMQERLPEHEER 748
++ Q+E K +E++ + EE+
Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQ 381
Score = 169 bits (428), Expect = 1e-41
Identities = 107/325 (32%), Positives = 202/325 (62%), Gaps = 19/325 (5%)
Query: 72 EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG 131
E++ + QE RE E Q +R Q E E + + R+ E G+ ++ G
Sbjct: 126 EQEGQVREQEGQVREQEGQ---VREQEGQVREQEGQVREQEGQVREQE----GQVREQEG 178
Query: 132 RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAE 191
++ G+++ + + E++ ++ + + + + E+++K+ +
Sbjct: 179 QVREQ---EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
Query: 192 LQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 251
+ E+ + ++ ++Q ++++++ E+ + Q++ QEE +++E EQE++
Sbjct: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE---QEEQMLKQKEQTEQEEQTG 292
Query: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK---ELREQKKLREQ 308
+QEE+M QEE++REQE +MREQEE+MR QE+++ +QE+++ EQ++ E +EQ + +Q
Sbjct: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQ 350
Query: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
EEQM EQEE+M +QEE++R+QEE+M +QEE++ +QE+QMR+QE++M +Q+E+M EQ E++
Sbjct: 351 EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQM 410
Query: 369 REKEERMREQ-EKMWEQEEKMQEEE 392
RE+EE+M EQ E+M +QEE M E++
Sbjct: 411 REQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 120 bits (302), Expect = 4e-27
Identities = 65/179 (36%), Positives = 122/179 (68%), Gaps = 12/179 (6%)
Query: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
EE +E++ L+ T E +++ E +E++R E + E + ++E + ++ +
Sbjct: 268 EEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Query: 222 FLLPQVQTNTLQ--EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279
+ + + + E+MW Q+E++ +QE+++ +QEE+M +QEE++R+QE +MR+QEE+MR
Sbjct: 324 EQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMR 383
Query: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
+QE+++R+QE+++ EQ++++ EQK EQM+EQEE+M EQ+E+MR+QEE M Q+E
Sbjct: 384 KQEEQMRKQEEQMGEQKEQMGEQK------EQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 423 bits (1088), Expect = e-118
Identities = 237/449 (52%), Positives = 325/449 (72%), Gaps = 46/449 (10%)
Query: 160 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER 219
YIE+LTKERDALSLELYRNTIT+EELK+KNAELQEKLRL ESEKSEIQLNVK+LKRKLER
Sbjct: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMW-----RQEERLREQEGKMR 272
A+ LLPQ Q LQ E R +EL+ K++ Q E ++W +QEE++ QE K++
Sbjct: 251 AQLLLPQQQ---LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
Query: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
EQEEKM QE ++REQE EK R+++K+ EQEE+++EQE+KMW QEEK+REQEEK
Sbjct: 308 EQEEKMCEQELKIREQE------EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361
Query: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE- 391
+ QEE++W QE+++REQ++K+++QEE MW Q+E++RE+EE+ QEKMW QE+KM+E+
Sbjct: 362 IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK--RQEKMWRQEKKMREQD 419
Query: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
E+IRE+E++M +EE +RE EE MQ QEE + E EEK + E+EKMQEQ
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE------------EEEKMQEQ 467
Query: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE 511
EEKI QEEKI++QEE K WRQEK+ +QE+++WEQEEKM QE+KMW+QEE+M E
Sbjct: 468 EEKIQRQEEKIQEQEE------KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Query: 512 QDERLREKEERMREQK-KMWQQEEKMRE-EKKTQEQEKKTWDQEEKM-------REEERM 562
Q+E+++ +EE+MREQ+ ++WQQEEKM+E E + QE E++ +K RE
Sbjct: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQ 581
Query: 563 REREKKMREEEEMMREQEEKMQEQEEKMR 591
R + E+ ++ + +Q+Q++ R
Sbjct: 582 RLPTLTPILQVELKSQEAQSLQQQQDHYR 610
Score = 348 bits (894), Expect = 9e-96
Identities = 222/561 (39%), Positives = 347/561 (61%), Gaps = 58/561 (10%)
Query: 195 KLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 254
K + E S++ ++ +L+++ + + + ++ +E + Q E+ + +++
Sbjct: 21 KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRG 80
Query: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314
K W +++ L E E ++ +E ++R L + E E +K E + ++
Sbjct: 81 TKRWDEDDDLEESEDS-KQCKESLKRVTFTLPDDEAI--EDAGVSHVKKNSDEVKSSFKK 137
Query: 315 QEEKMWEQEEKMREQE--EKMWRQEERLWEQEKQMREQEQKMR-----DQEERMWEQDER 367
++EKM E+ R++ +K W RL E Q R + + D RM E+
Sbjct: 138 RQEKMNEKNYTFRKRVVIKKPWL---RLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEK 194
Query: 368 LREKEERMREQ--------EKMWEQEEKMQEEERIREREK----------KMREEEETMR 409
L ++ + + + E++ E+ ++QE+ R+ E EK K + E +
Sbjct: 195 LTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 410 EQEEKMQKQEENMWEQ------------EEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIW 456
++++Q + + + ++ EE E +Q+EK+W QE K+QEQEEK+
Sbjct: 255 LPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC 314
Query: 457 EQEEKIRDQEE-MWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
EQE KIR+QEE MW QE+KM QE K+REQED+MW QEEK+R+QE+K+ +QEE+MW Q+E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 515 RLREKEERMREQ-KKMWQQEEKMRE-EKKTQE----QEKKTWDQEEKMRE-EERMREREK 567
++RE++E+++EQ ++MW+QEEK+RE E+K QE QEKK +Q+EK+RE EE M +E+
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
K+RE EEMM++QEEK++E EEKM+E+EEKM EQEEK+Q QEEK+ EQEEK W QE K+
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE---KL 491
Query: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
+QEE +WEQEEKM QEEKMWEQEEKM+EQEEKM+ QEEKM+ QE ++ +QEEKMQ QE
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 688 EKMREQEEKM--RGQEEKMWG 706
+++E EE++ GQ+ ++ G
Sbjct: 552 VRLQELEERLGKLGQKAELLG 572
Score = 304 bits (779), Expect = 2e-82
Identities = 207/561 (36%), Positives = 321/561 (57%), Gaps = 80/561 (14%)
Query: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER---MWEQDERLREKEERMRE 377
EQ+ K+R + R++ E+ Q+ E E + +++ R W++D+ L E E+ +
Sbjct: 40 EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99
Query: 378 QEKMWEQEEKMQEEERI-------------------REREKKMREEEETMREQ------- 411
+E + + ++E I ++R++KM E+ T R++
Sbjct: 100 KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPW 159
Query: 412 ----EEKMQKQEENMWEQEEKEWQQQ-RLPEQKEKLWEQEKM------------QEQEEK 454
E QK+ EN +E + R+ EKL ++ +E +EK
Sbjct: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEK 219
Query: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
E +EK+R E + + + K + + Q+ +++++ + ++ + + + + +
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279
Query: 515 RLREKEE-----RMREQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKM-REEERMREREK 567
E+ E ++++KMW+QEEK++E E+K EQE K +QEEKM R+EE+M E+E+
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
K+RE+E+ M QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE+MW QEE+ +
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399
Query: 628 QEQ--EEMMWEQEEKMQEQEEK-------MWEQEEKMRE-------QEEKMREQEEKMQG 671
QE+ +E MW QE+KM+EQ+EK MW QEEK+RE QEEK+RE EEKMQ
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 672 QEEKMREQEEKMQGQEEKMREQE------EKMRGQEEKMWGQEEKMWGQEEKMWGQEE-M 724
+EEKM+EQEEK+Q QEEK++EQE EK+ QEEK+W QEEKMW QEEKMW QEE M
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKM 519
Query: 725 REKEERIRDQKEKMQE---RLPEHEERCSEPCLPPSKVLCNMSHTG-SVEPAGGEAGEGS 780
+E+EE+++ Q+EKM+E RL + EE+ E + ++ + G E GG E
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 781 PQDNPTAQEIMQLFCGMKNAQ 801
Q PT I+Q+ + AQ
Sbjct: 580 SQRLPTLTPILQVELKSQEAQ 600
Score = 203 bits (517), Expect = 5e-52
Identities = 125/383 (32%), Positives = 224/383 (58%), Gaps = 51/383 (13%)
Query: 81 EALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFA 140
+++ +++AQ + + E ++ ++ ++ E+ + + + W
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 141 GELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAE 200
++ + K R E++ ++ + + + + E++++++ ++QE+
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ----- 386
Query: 201 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 260
+EEMWRQEE++REQE+ K++EKMWRQ
Sbjct: 387 --------------------------------EEEMWRQEEKIREQEE---KRQEKMWRQ 411
Query: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE-QKKLREQEEQMQEQEEKM 319
E+++REQ+ K+REQEE+M RQE+++RE E+ +++QE++LRE ++K++E+EE+MQEQEEK+
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471
Query: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
QEEK++EQEEK WRQ E+L +QE+++ EQE+KM QEE+MWEQ+E+++E+EE
Sbjct: 472 QRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE------ 524
Query: 380 KMWEQEEKMQEEE-RIREREKKMREEEETMREQEEKMQK--QEENMWEQEEKEWQQQRLP 436
KM QEEKM+E+E R+ ++E+KM+E+E ++E EE++ K Q+ + +E QRLP
Sbjct: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLP 584
Query: 437 EQKEKLWEQEKMQEQEEKIWEQE 459
L + K QE + +Q+
Sbjct: 585 TLTPILQVELKSQEAQSLQQQQD 607
Score = 200 bits (508), Expect = 5e-51
Identities = 137/432 (31%), Positives = 239/432 (55%), Gaps = 51/432 (11%)
Query: 339 RLWEQEKQMREQEQKMRDQ---EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395
+L +Q K + K R++ +E+ ++ E E R R K W++++ ++E E +
Sbjct: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
Query: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455
+ ++ ++ T+ + E ++ + ++ + ++++EK+
Sbjct: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEV---------------KSSFKKRQEKM 142
Query: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
E+ R + + KK W +R E ++ E +E +D RM E+
Sbjct: 143 NEKNYTFRKRVVI----KKPW----LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEK 194
Query: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
L ++ + + + ++ +EK + QEK + EK + +++ ++K+ + +
Sbjct: 195 LTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW-----EQEEKMWEQEEEDKMQEQ 630
+ +Q+ +Q + +++ ++ + + + + Q +E ++W +QEEKMW QEE K+QEQ
Sbjct: 255 LPQQQ--LQVEADRLGKELQSV-SAKLQAQVEENELWNLLNQQQEEKMWRQEE--KIQEQ 309
Query: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
EE M EQE K++EQEEKMW QEEKM EQEEK+REQE+KM QEEK+REQEEK++ QEEKM
Sbjct: 310 EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 691 REQEEKMRGQEEKMWGQEEKMWGQE-----------EKMWGQE-EMREKEERIRDQKEKM 738
QEEK+R Q+EK+ QEE+MW QE EKMW QE +MRE++E+IR+Q+E+M
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
Query: 739 ---QERLPEHEE 747
+E++ E EE
Sbjct: 430 WRQEEKIRELEE 441
Score = 134 bits (337), Expect = 3e-31
Identities = 95/339 (28%), Positives = 182/339 (53%), Gaps = 28/339 (8%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
+ E+K Q ++ +E + + ++I E E ++ ++ + E+ + E +D
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKI-----REQEEKMWRQEEKMHEQEE-KIREQED- 346
Query: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
W +++ + +K R E++ ++ + + + E+++++
Sbjct: 347 -----KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401
Query: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
+ QEK+ E + E ++E + ++ R + + L+E M QEE+LRE E+K
Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQ-----EEKIRELEEMMQDQEEKLREVEEK 456
Query: 250 I-----RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
+ + QE QEE+++ QE K++EQEEK RQEK L+++EK ++EK R+++K
Sbjct: 457 MQEEEEKMQE-----QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
Query: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
+ EQEE+MQEQEEKM QEEKMREQE ++W+QEE++ EQE +++E E+++ ++
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571
Query: 365 DERLREK-EERMREQEKMWEQEEKMQEEERIREREKKMR 402
RE +R+ + + E K QE + +++++ R
Sbjct: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
Score = 41.6 bits (96), Expect = 0.003
Identities = 51/279 (18%), Positives = 118/279 (42%), Gaps = 38/279 (13%)
Query: 64 EGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNL 123
E E++++ QE RE QD IR E E ++ ++ R+ E+
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMRE---QDEKIR-------EQEEEMWRQEEKIRELEEMMQ 444
Query: 124 GESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNE 183
+ + L ++Q + +K R E++ ++ + T E
Sbjct: 445 DQEEKLR-------EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE--------KTWRQE 489
Query: 184 ELKKKNAEL---QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
+L K+ ++ +EK+ E + E + ++E + K++R + + + + +W+QE
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR-----LWQQE 544
Query: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
E+++EQE ++++ EE++ + ++ G RE + + + E + +E + +
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Query: 301 EQKKLREQEEQMQEQEEKMWEQEEKM-----REQEEKMW 334
+Q R +Q +++ +E + R+ K W
Sbjct: 605 QQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 406 bits (1044), Expect = e-113
Identities = 230/450 (51%), Positives = 320/450 (71%), Gaps = 48/450 (10%)
Query: 160 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER 219
YIE+LTKERDA SLELYRNTIT+EELK+KNAELQEKLRL ESEKSEIQLNVK+LKRKLER
Sbjct: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMW-----RQEERLREQEGKMR 272
A+ LLPQ Q LQ E R +EL+ K++ Q E ++W +QEE++ QE K++
Sbjct: 251 AQLLLPQQQ---LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
Query: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
EQEEKM QE ++REQE EK R+++K+ EQEE+++EQE+KMW QEEK+REQEEK
Sbjct: 308 EQEEKMCEQELKIREQE------EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361
Query: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE- 391
+ QEE++W QE+++REQ++K+++QEE MW Q+E++RE+EE+ QEKMW QE+KM+E+
Sbjct: 362 IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK--RQEKMWRQEKKMREQD 419
Query: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQE-KMQ 449
E+IRE+E++M +EE +RE EE MQ QEE + E EEK + +++++ EQ+EK+ QE K+Q
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 450 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 509
EQEEK W QE+ ++ +E++W QE+KMWRQE ++MWEQEEKM++QE+KM QEE+M
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQE------EKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 510 WEQDERLREKEERMREQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKM-------REEER 561
EQ+ RL WQQEEKM+E E + QE E++ +K RE
Sbjct: 534 REQEVRL-------------WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGS 580
Query: 562 MREREKKMREEEEMMREQEEKMQEQEEKMR 591
R + E+ ++ + +Q+Q++ R
Sbjct: 581 QRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
Score = 348 bits (894), Expect = 9e-96
Identities = 223/559 (39%), Positives = 346/559 (61%), Gaps = 54/559 (9%)
Query: 195 KLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 254
K + E S++ ++ +L+++ + + + ++ +E + Q E+ + +++
Sbjct: 21 KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRG 80
Query: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314
K W +++ L E E ++ +E ++R L + E E +K E + ++
Sbjct: 81 TKRWDEDDDLEESEDS-KQCKESLKRVTFTLPDDEAI--EDAGVSHVKKNSDEVKSSFKK 137
Query: 315 QEEKMWEQEEKMREQE--EKMW----------RQEERLWEQEKQMR---------EQEQK 353
++EKM E+ R++ +K W R E L E+ E+ K
Sbjct: 138 RQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK 197
Query: 354 MRDQEE----RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
RD R DE L+EK ++E+ ++ E E K + + +++ ++K+ + +
Sbjct: 198 ERDAPSLELYRNTITDEELKEKNAELQEKLRLVESE-KSEIQLNVKDLKRKLERAQLLLP 256
Query: 410 EQE---------EKMQKQEENMWEQ-EEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIWEQ 458
+Q+ +++Q + Q EE E +Q+EK+W QE K+QEQEEK+ EQ
Sbjct: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQ 316
Query: 459 EEKIRDQEE-MWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516
E KIR+QEE MW QE+KM QE K+REQED+MW QEEK+R+QE+K+ +QEE+MW Q+E++
Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 517 REKEERMREQ-KKMWQQEEKMRE-EKKTQE----QEKKTWDQEEKMRE-EERMREREKKM 569
RE++E+++EQ ++MW+QEEK+RE E+K QE QEKK +Q+EK+RE EE M +E+K+
Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
Query: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629
RE EEMM++QEEK++E EEKM+E+EEKM EQEEK+Q QEEK+ EQEEK W QE K+ +
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE---KLLK 493
Query: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689
QEE +WEQEEKM QEEKMWEQEEKM+EQEEKM+ QEEKM+ QE ++ +QEEKMQ QE +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 690 MREQEEKM--RGQEEKMWG 706
++E EE++ GQ+ ++ G
Sbjct: 554 LQELEERLGKLGQKAELLG 572
Score = 304 bits (779), Expect = 2e-82
Identities = 207/561 (36%), Positives = 321/561 (57%), Gaps = 80/561 (14%)
Query: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER---MWEQDERLREKEERMRE 377
EQ+ K+R + R++ E+ Q+ E E + +++ R W++D+ L E E+ +
Sbjct: 40 EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99
Query: 378 QEKMWEQEEKMQEEERI-------------------REREKKMREEEETMREQ------- 411
+E + + ++E I ++R++KM E+ T R++
Sbjct: 100 KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPW 159
Query: 412 ----EEKMQKQEENMWEQEEKEWQQQ-RLPEQKEKLWEQEKM------------QEQEEK 454
E QK+ EN +E + R+ EKL ++ +E +EK
Sbjct: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEK 219
Query: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
E +EK+R E + + + K + + Q+ +++++ + ++ + + + + +
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279
Query: 515 RLREKEE-----RMREQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKM-REEERMREREK 567
E+ E ++++KMW+QEEK++E E+K EQE K +QEEKM R+EE+M E+E+
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
K+RE+E+ M QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE+MW QEE+ +
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399
Query: 628 QEQ--EEMMWEQEEKMQEQEEK-------MWEQEEKMRE-------QEEKMREQEEKMQG 671
QE+ +E MW QE+KM+EQ+EK MW QEEK+RE QEEK+RE EEKMQ
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 672 QEEKMREQEEKMQGQEEKMREQE------EKMRGQEEKMWGQEEKMWGQEEKMWGQEE-M 724
+EEKM+EQEEK+Q QEEK++EQE EK+ QEEK+W QEEKMW QEEKMW QEE M
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKM 519
Query: 725 REKEERIRDQKEKMQE---RLPEHEERCSEPCLPPSKVLCNMSHTG-SVEPAGGEAGEGS 780
+E+EE+++ Q+EKM+E RL + EE+ E + ++ + G E GG E
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 781 PQDNPTAQEIMQLFCGMKNAQ 801
Q PT I+Q+ + AQ
Sbjct: 580 SQRLPTLTPILQVELKSQEAQ 600
Score = 203 bits (517), Expect = 5e-52
Identities = 125/383 (32%), Positives = 224/383 (58%), Gaps = 51/383 (13%)
Query: 81 EALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFA 140
+++ +++AQ + + E ++ ++ ++ E+ + + + W
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 141 GELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAE 200
++ + K R E++ ++ + + + + E++++++ ++QE+
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ----- 386
Query: 201 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 260
+EEMWRQEE++REQE+ K++EKMWRQ
Sbjct: 387 --------------------------------EEEMWRQEEKIREQEE---KRQEKMWRQ 411
Query: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE-QKKLREQEEQMQEQEEKM 319
E+++REQ+ K+REQEE+M RQE+++RE E+ +++QE++LRE ++K++E+EE+MQEQEEK+
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471
Query: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
QEEK++EQEEK WRQ E+L +QE+++ EQE+KM QEE+MWEQ+E+++E+EE
Sbjct: 472 QRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE------ 524
Query: 380 KMWEQEEKMQEEE-RIREREKKMREEEETMREQEEKMQK--QEENMWEQEEKEWQQQRLP 436
KM QEEKM+E+E R+ ++E+KM+E+E ++E EE++ K Q+ + +E QRLP
Sbjct: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLP 584
Query: 437 EQKEKLWEQEKMQEQEEKIWEQE 459
L + K QE + +Q+
Sbjct: 585 TLTPILQVELKSQEAQSLQQQQD 607
Score = 200 bits (508), Expect = 5e-51
Identities = 140/433 (32%), Positives = 242/433 (55%), Gaps = 53/433 (12%)
Query: 339 RLWEQEKQMREQEQKMRDQ---EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395
+L +Q K + K R++ +E+ ++ E E R R K W++++ ++E E +
Sbjct: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
Query: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455
+ ++ ++ T+ + E ++ + ++ + ++++EK+
Sbjct: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEV---------------KSSFKKRQEKM 142
Query: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
E+ R + + KK W +R E ++ E +E +D RM E+
Sbjct: 143 NEKNYTFRKRVVI----KKPW----LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEK 194
Query: 516 L-REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
L +E++ E + +E+++E K + QEK + EK + +++ ++K+ +
Sbjct: 195 LTKERDAPSLELYRNTITDEELKE-KNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL 253
Query: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW-----EQEEKMWEQEEEDKMQE 629
++ +Q+ +Q + +++ ++ + + + + Q +E ++W +QEEKMW QEE K+QE
Sbjct: 254 LLPQQQ--LQVEADRLGKELQSV-SAKLQAQVEENELWNLLNQQQEEKMWRQEE--KIQE 308
Query: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689
QEE M EQE K++EQEEKMW QEEKM EQEEK+REQE+KM QEEK+REQEEK++ QEEK
Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368
Query: 690 MREQEEKMRGQEEKMWGQEEKMWGQE-----------EKMWGQE-EMREKEERIRDQKEK 737
M QEEK+R Q+EK+ QEE+MW QE EKMW QE +MRE++E+IR+Q+E+
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428
Query: 738 M---QERLPEHEE 747
M +E++ E EE
Sbjct: 429 MWRQEEKIRELEE 441
Score = 134 bits (337), Expect = 3e-31
Identities = 95/339 (28%), Positives = 182/339 (53%), Gaps = 28/339 (8%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
+ E+K Q ++ +E + + ++I E E ++ ++ + E+ + E +D
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKI-----REQEEKMWRQEEKMHEQEE-KIREQED- 346
Query: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
W +++ + +K R E++ ++ + + + E+++++
Sbjct: 347 -----KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401
Query: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
+ QEK+ E + E ++E + ++ R + + L+E M QEE+LRE E+K
Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQ-----EEKIRELEEMMQDQEEKLREVEEK 456
Query: 250 I-----RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
+ + QE QEE+++ QE K++EQEEK RQEK L+++EK ++EK R+++K
Sbjct: 457 MQEEEEKMQE-----QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
Query: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
+ EQEE+MQEQEEKM QEEKMREQE ++W+QEE++ EQE +++E E+++ ++
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571
Query: 365 DERLREK-EERMREQEKMWEQEEKMQEEERIREREKKMR 402
RE +R+ + + E K QE + +++++ R
Sbjct: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
Score = 41.6 bits (96), Expect = 0.003
Identities = 51/279 (18%), Positives = 118/279 (42%), Gaps = 38/279 (13%)
Query: 64 EGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNL 123
E E++++ QE RE QD IR E E ++ ++ R+ E+
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMRE---QDEKIR-------EQEEEMWRQEEKIRELEEMMQ 444
Query: 124 GESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNE 183
+ + L ++Q + +K R E++ ++ + T E
Sbjct: 445 DQEEKLR-------EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE--------KTWRQE 489
Query: 184 ELKKKNAEL---QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
+L K+ ++ +EK+ E + E + ++E + K++R + + + + +W+QE
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR-----LWQQE 544
Query: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
E+++EQE ++++ EE++ + ++ G RE + + + E + +E + +
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Query: 301 EQKKLREQEEQMQEQEEKMWEQEEKM-----REQEEKMW 334
+Q R +Q +++ +E + R+ K W
Sbjct: 605 QQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 366 bits (939), Expect = e-101
Identities = 200/274 (72%), Positives = 220/274 (80%), Gaps = 37/274 (13%)
Query: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM---- 56
Query: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
WEQEE KM EQEE MWEQ +++ EQ+EKMWEQ+E++RE+EE+MREQ KM Q EK
Sbjct: 57 ---WEQEE--KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEK 108
Query: 676 MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE-MREKEERIRDQ 734
MR EK + QEEKM+EQEEKM+ QEE MW QEEKM QEEKMW QEE MRE+EE++R+Q
Sbjct: 109 MR---EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165
Query: 735 KEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEIMQLF 794
+EKMQ + EE+ + VEPAGGEAGEGSPQDNPTAQEIMQLF
Sbjct: 166 EEKMQGQ----EEKMRD-----------------VEPAGGEAGEGSPQDNPTAQEIMQLF 204
Query: 795 CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 828
CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI
Sbjct: 205 CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 238
Score = 238 bits (606), Expect = 2e-62
Identities = 125/212 (58%), Positives = 167/212 (78%), Gaps = 20/212 (9%)
Query: 280 RQEKRLREQEKELREQEKELREQK-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
R+E+R+RE+EK++RE+E+ +REQ+ K++EQEE+M+EQEEKMWEQEEKM+EQEEKMW QEE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE-----EER 393
++WEQE++M EQ Q++ +Q+E+MWEQDERLREKEERMREQ KMW+Q EKM+E EE+
Sbjct: 62 KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQEEK 119
Query: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453
++E+E+KM+E+EE M EQEEKMQ+QEE MWEQEEK +Q +EKM+EQEE
Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ------------EEKMREQEE 167
Query: 454 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
K+ QEEK+RD E G+ + Q+ QE
Sbjct: 168 KMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
Score = 228 bits (582), Expect = 1e-59
Identities = 138/242 (57%), Positives = 161/242 (66%), Gaps = 69/242 (28%)
Query: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 447
M+EEER+REREKKMRE E+E
Sbjct: 1 MREEERMREREKKMRE----------------------------------------EEEM 20
Query: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQE 506
M+EQEEK+ EQEEK+R+QEE KMW QE KM+EQE++MWEQEEKM +QE+KMW+Q+
Sbjct: 21 MREQEEKMQEQEEKMREQEE------KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 74
Query: 507 ------ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
E+MWEQDERLREKEERMREQK MWQQ EKMRE+KKTQE EKM+E+
Sbjct: 75 RLPEQKEKMWEQDERLREKEERMREQK-MWQQVEKMREKKKTQE---------EKMQEQ- 123
Query: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE 620
E+KM+E+EEMM EQEEKMQEQEEKM EQEEKM EQEEKM+EQEEKM QEEKM +
Sbjct: 124 -----EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Query: 621 QE 622
E
Sbjct: 179 VE 180
Score = 226 bits (576), Expect = 7e-59
Identities = 123/193 (63%), Positives = 157/193 (81%), Gaps = 18/193 (9%)
Query: 505 QEERMWEQDERLREKEERMREQK-KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
+EERM E+++++RE+EE MREQ+ KM +QEEKMRE QE+K W+QEEKM+E+E
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMRE------QEEKMWEQEEKMQEQE--- 53
Query: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
+KM E+EE M EQEEKM EQ +++ EQ+EKMWEQ+E+++E+EE+M +E+KMW+Q E
Sbjct: 54 ---EKMWEQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERM--REQKMWQQVE 107
Query: 624 E--DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
+ +K + QEE M EQEEKMQEQEE MWEQEEKM+EQEEKM EQEEKM+ QEEKMREQEE
Sbjct: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
Query: 682 KMQGQEEKMREQE 694
KMQGQEEKMR+ E
Sbjct: 168 KMQGQEEKMRDVE 180
Score = 223 bits (568), Expect = 6e-58
Identities = 114/180 (63%), Positives = 150/180 (83%), Gaps = 8/180 (4%)
Query: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKM 529
+E+ R++KMRE+E+ M EQEEKM++QE+KM +QEE+MWEQ+E+++E+EE+M EQ +KM
Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
Query: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE----QEEKMQE 585
W+QEEKM E+++ EQ++K W+Q+E++RE+E R RE+KM ++ E MRE QEEKMQE
Sbjct: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEE-RMREQKMWQQVEKMREKKKTQEEKMQE 122
Query: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645
QEEKM+EQEE MWEQEEKMQEQEEKMWEQEEKM EQEE KM+EQEE M QEEKM++ E
Sbjct: 123 QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE--KMREQEEKMQGQEEKMRDVE 180
Score = 223 bits (567), Expect = 7e-58
Identities = 123/204 (60%), Positives = 161/204 (78%), Gaps = 14/204 (6%)
Query: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK-KMWQQEEKMRE-EKKTQEQEKK 548
+EE+MR++E+KM ++EE M EQ+E+++E+EE+MREQ+ KMW+QEEKM+E E+K EQE+K
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKM 604
W+QEEKM E++R+ E+++KM E++E +RE+EE+M+EQ KM +Q EKM E QEEKM
Sbjct: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEKM 120
Query: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
QEQEEKM EQEE MWEQEE KMQEQEE MWEQEEKM+EQEEKM EQEEKM+ QEEKMR+
Sbjct: 121 QEQEEKMQEQEEMMWEQEE--KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Query: 665 QE----EKMQGQEEKMREQEEKMQ 684
E E +G + +E MQ
Sbjct: 179 VEPAGGEAGEGSPQDNPTAQEIMQ 202
Score = 220 bits (561), Expect = 4e-57
Identities = 108/188 (57%), Positives = 156/188 (82%), Gaps = 10/188 (5%)
Query: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
E+E+M+E+E+K+ E+EE +R+QEE K ++EKMREQE++MWEQEEKM++QE+KMW
Sbjct: 3 EEERMREREKKMREEEEMMREQEE-----KMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 57
Query: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
+QEE+MWEQ+E++ E++ +++KMW+Q+E++RE K+ + +E+K W Q EKMRE+++ +
Sbjct: 58 EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLRE-KEERMREQKMWQQVEKMREKKKTQ 116
Query: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
E +KM+E+EE M+EQEE M EQEEKM+EQEEKMWEQEEKM+EQEEKM EQEEKM Q +
Sbjct: 117 E--EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM--QGQ 172
Query: 624 EDKMQEQE 631
E+KM++ E
Sbjct: 173 EEKMRDVE 180
Score = 214 bits (546), Expect = 2e-55
Identities = 112/184 (60%), Positives = 153/184 (83%), Gaps = 17/184 (9%)
Query: 364 QDERLREKEERMREQEKMW-EQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEEN 421
++ER+RE+E++MRE+E+M EQEEKMQE EE++RE+E+KM E+EE M+EQEEKM +QEE
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 422 MWEQEEKEWQQQRLPEQKEKLWEQ-EKMQEQEE-----KIWEQEEKIRDQEEMWGQEKKM 475
MWEQEEK W+QQRLPEQKEK+WEQ E+++E+EE K+W+Q EK+R++++ QE+KM
Sbjct: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT--QEEKM 120
Query: 476 WRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534
QE KM+EQE+ MWEQEEKM++QE+KMW+QEE+M EQ+E++RE+EE KM QEE
Sbjct: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE------KMQGQEE 174
Query: 535 KMRE 538
KMR+
Sbjct: 175 KMRD 178
Score = 207 bits (528), Expect = 2e-53
Identities = 110/196 (56%), Positives = 155/196 (79%), Gaps = 13/196 (6%)
Query: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE-K 380
+EE+MRE+E+KM +EE + EQE++M+EQE+KMR+QEE+MWEQ+E+++E+EE+M EQE K
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
MWEQEEKM E++R+ E+++KM E++E +RE+EE+M +E+ MW+Q EK +++ Q+E
Sbjct: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEK--MREKKKTQEE 118
Query: 441 KLWEQ-EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEKMRDQ 498
K+ EQ EKMQEQEE +WEQEEK+++QEE KMW Q EKMREQE++M EQEEKM+ Q
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEE------KMWEQEEKMREQEEKMREQEEKMQGQ 172
Query: 499 EQKMWDQEERMWEQDE 514
E+KM D E E E
Sbjct: 173 EEKMRDVEPAGGEAGE 188
Score = 199 bits (506), Expect = 9e-51
Identities = 100/187 (53%), Positives = 153/187 (81%), Gaps = 13/187 (6%)
Query: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
R+EE +RE+EKK+R++EE M QEE+++EQE KMREQEEKM QE++++EQE+++ EQE+
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE----QEQK 353
++ EQ++ +++++ EQ+EKMWEQ+E++RE+EE+M +E+++W+Q ++MRE QE+K
Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMREKKKTQEEK 119
Query: 354 MRDQEERMWEQDERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMREEEETMREQE 412
M++QEE+M EQ+E + E+EE+M+EQ EKMWEQEEKM RE+E+KMRE+EE M+ QE
Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEEKMREQEEKMQGQE 173
Query: 413 EKMQKQE 419
EKM+ E
Sbjct: 174 EKMRDVE 180
Score = 192 bits (487), Expect = 1e-48
Identities = 107/194 (55%), Positives = 153/194 (78%), Gaps = 23/194 (11%)
Query: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE-EER 393
R+EER+ E+EK+MRE+E+ MR+QEE+M EQ+E++RE+EE KMWEQEEKMQE EE+
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE------KMWEQEEKMQEQEEK 55
Query: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQ-EKMQE- 450
+ E+E+KM E+EE M EQ +++ +Q+E MWEQ+E+ +++R+ EQ K+W+Q EKM+E
Sbjct: 56 MWEQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREK 112
Query: 451 ---QEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEKMRDQEQKMWDQE 506
QEEK+ EQEEK+++QEEM MW Q EKM+EQE++MWEQEEKMR+QE+KM +QE
Sbjct: 113 KKTQEEKMQEQEEKMQEQEEM------MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166
Query: 507 ERMWEQDERLREKE 520
E+M Q+E++R+ E
Sbjct: 167 EKMQGQEEKMRDVE 180
Score = 177 bits (449), Expect = 4e-44
Identities = 102/194 (52%), Positives = 142/194 (73%), Gaps = 25/194 (12%)
Query: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG 269
++E +R ER K + + +E M QEE+++EQE+K+R+QEEKMW QEE+++EQE
Sbjct: 1 MREEERMREREKKMREE------EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54
Query: 270 KMREQEEKMRRQEK------RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
KM EQEEKM QE+ RL EQ++++ EQ++ L RE+EE+M+EQ KMW+Q
Sbjct: 55 KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERL------REKEERMREQ--KMWQQV 106
Query: 324 EKMRE----QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ- 378
EKMRE QEEKM QEE++ EQE+ M EQE+KM++QEE+MWEQ+E++RE+EE+MREQ
Sbjct: 107 EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166
Query: 379 EKMWEQEEKMQEEE 392
EKM QEEKM++ E
Sbjct: 167 EKMQGQEEKMRDVE 180
Score = 168 bits (425), Expect = 2e-41
Identities = 88/184 (47%), Positives = 137/184 (74%), Gaps = 11/184 (5%)
Query: 193 QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 252
+E++R E + E + ++E + K++ + + +E+MW QEE+++EQE+K+ +
Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQEQ-----EEKMREQEEKMWEQEEKMQEQEEKMWE 58
Query: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE--- 309
QEEKMW QEE++ EQ+ ++ EQ+EKM Q++RLRE+E+ +REQ K ++ +K+RE++
Sbjct: 59 QEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQ 116
Query: 310 -EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
E+MQEQEEKM EQEE M EQEEKM QEE++WEQE++MREQE+KMR+QEE+M Q+E++
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 369 REKE 372
R+ E
Sbjct: 177 RDVE 180
Score = 157 bits (397), Expect = 4e-38
Identities = 87/180 (48%), Positives = 130/180 (72%), Gaps = 14/180 (7%)
Query: 184 ELKKKNAELQEKLRLAESEKSEIQLNVKELKRKL-ERAKFLLPQVQTNTLQEE-MWRQEE 241
E +KK E +E +R E + E + ++E + K+ E+ + + Q + QEE MW QEE
Sbjct: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68
Query: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
++ EQ++ + +Q+EKMW Q+ERLRE+E +MREQ KM +Q +++RE++K +
Sbjct: 69 KMWEQQR-LPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK---------TQ 116
Query: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
++K++EQEE+MQEQEE MWEQEEKM+EQEEKMW QEE++ EQE++MREQE+KM+ QEE+M
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Score = 124 bits (310), Expect = 5e-28
Identities = 73/169 (43%), Positives = 113/169 (66%), Gaps = 19/169 (11%)
Query: 184 ELKKKNAELQEKLRLAESEKSEIQLNVKELKRKL--------ERAKFLLPQVQTNTLQEE 235
E ++K E +EK+R E + E + ++E + K+ E+ + + Q + +E+
Sbjct: 23 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK 82
Query: 236 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ 295
MW Q+E LRE+E+++R E+KMW+Q E++RE K + QEEKM+ QE++++EQE+ + EQ
Sbjct: 83 MWEQDERLREKEERMR--EQKMWQQVEKMRE---KKKTQEEKMQEQEEKMQEQEEMMWEQ 137
Query: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
E +K++EQEE+M EQEEKM EQEEKMREQEEKM QEE++ + E
Sbjct: 138 E------EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
Score = 95.1 bits (235), Expect = 2e-19
Identities = 48/119 (40%), Positives = 85/119 (71%), Gaps = 1/119 (0%)
Query: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
E++ ++ ++ E+ RL E +K ++ + L+ K ER + Q ++E+ QEE+
Sbjct: 61 EKMWEQEEKMWEQQRLPE-QKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
Query: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
++EQE+K+++QEE MW QEE+++EQE KM EQEEKMR QE+++REQE++++ QE+++R+
Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Score = 80.9 bits (198), Expect = 5e-15
Identities = 47/128 (36%), Positives = 72/128 (56%), Gaps = 7/128 (5%)
Query: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
EE E++ E R E++ +++ L+EK +K Q+ K+K + K
Sbjct: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
Query: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ 281
+ + +E MW QEE+++E QEEKMW QEE++REQE KMREQEEKM+ Q
Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQE-------QEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
Query: 282 EKRLREQE 289
E+++R+ E
Sbjct: 173 EEKMRDVE 180
Score = 51.6 bits (122), Expect = 3e-06
Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Query: 153 WHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE 212
W ++ + ++ E+ E EE ++ Q+ ++ E +K++ + ++
Sbjct: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
Query: 213 LKRKLERAKFLLPQVQTNTLQEEMWR-QEEELREQEKKIRKQEEKMWRQEERLREQE 268
++ E+ + + Q + QEE QEE++REQE+K+R+QEEKM QEE++R+ E
Sbjct: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 296 bits (757), Expect = 7e-80
Identities = 238/816 (29%), Positives = 412/816 (50%), Gaps = 86/816 (10%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
E+EKK HQ Q ALR +++ TI IL +K EL+TAL ++Q AAR+ E GES+DL
Sbjct: 199 EEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQHAARQKE----GESEDL 254
Query: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
A RL +S GEL+RALSAVST KKADRY +ELTKERDAL LELY+NT +NE+LK++
Sbjct: 255 ASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNEDLKQEK 314
Query: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
+EL+EKLR+ +EK+ +QLN++EL++KLE + LL Q + + +Q ++ E+ +
Sbjct: 315 SELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQLQQAMEERAQ 374
Query: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE 309
+ E + + E +R+ + + + E ++ + R++ +++ EQ LRE+K+
Sbjct: 375 L---EAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTLREEKEC--SM 429
Query: 310 EQMQEQEEKMWEQEEKMREQEEKM-----WRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
++QE E + E +M E E++L + + +R++ + + Q + +
Sbjct: 430 SRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQD 489
Query: 365 DERL----REKEERMREQEK---MW--EQEEKMQEEERIREREKKMREEEETMREQEEKM 415
+E L RE+EER+ E E+ +W + E + Q E ++ + RE +E++
Sbjct: 490 NEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQL 549
Query: 416 QKQEENMWE--QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 473
+ + + E E EQ K +K+ E +EK+ E +E + E
Sbjct: 550 AELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSELKETV---------EL 600
Query: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533
K + +++Q DQ ++ Q++ ++E + Q + +++++Q+ +
Sbjct: 601 KSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQEAQGKAV 660
Query: 534 EKM--REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
+M +E ++TQE+ + Q +++R + + E + + RE+EE +E+EE+
Sbjct: 661 AEMARQELQETQERLEAATQQNQQLRAQLSLMAHPG---EGDGLDREEEEDEEEEEEEAV 717
Query: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED-----KMQEQEEMMWEQEEKMQE-QE 645
+ M E ++ +E + + EEE +++EQ + Q+
Sbjct: 718 AVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHLLASAQK 777
Query: 646 EKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMW 705
E + E +QG EK++ + ++ ++ ++E+ E++ + ++
Sbjct: 778 EPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELEHRCIQLS 837
Query: 706 GQEEKMWG-----QEEKMWGQEEMREKEE---RIRDQKEKMQERLPEHEE---------- 747
G+ + + Q ++ +E REKEE R+ KE+M+ +L E +E
Sbjct: 838 GETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLLELQELVLRLVGDRN 897
Query: 748 --------RCSEPCLPPSKV---------------LCNMSHTGSVEPAGGEAGEGSPQDN 784
P P+ LC +S GSVEPA GEA EGSP+DN
Sbjct: 898 EWHGRFLAAAQNPADEPTSGAPAPQELGAANQQGDLCEVSLAGSVEPAQGEAREGSPRDN 957
Query: 785 PTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDK 820
PTAQ+IMQL M+N ++ PGLGS CIPFFYR D+
Sbjct: 958 PTAQQIMQLLREMQNPRERPGLGSNPCIPFFYRADE 993
Score = 82.0 bits (201), Expect = 2e-15
Identities = 100/514 (19%), Positives = 229/514 (44%), Gaps = 58/514 (11%)
Query: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLR------------EQEEQMQEQEE 317
K+++Q +++ Q L E++KE +++ LREQ ++ E + + +
Sbjct: 186 KLKQQNQEITDQ---LEEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQH 242
Query: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQM----REQEQKMRDQEERMWEQDERLREKEE 373
++E + + ++ R+ E E+ + +Q++ R +E E+D E +
Sbjct: 243 AARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYK 302
Query: 374 RMREQEKMWEQEEKMQEEERIREREKK----MREEEETMREQEEKMQKQEENMWEQEEKE 429
+ E + +++ +++E+ R+ EK EE + E E + +Q + E +
Sbjct: 303 NTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDAN 362
Query: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Q Q+ E++ +L E Q E Q E+ + E + G E MWRQ + QM
Sbjct: 363 QQLQQAMEERAQL-EAHLGQVMESVRQLQMERDKYAENLKG-ESAMWRQ-----RMQQMS 415
Query: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE-------------QKKMWQQEEKM 536
EQ +R++++ R+ E + L E +M E ++++ + E +
Sbjct: 416 EQVHTLREEKE---CSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHL 472
Query: 537 REEKK--TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
R+E + + + + D E R ER ++ E+ EQ E ++ E M+
Sbjct: 473 RKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQNDR 532
Query: 595 ---EKMWEQEEKMQEQEEKMWEQEEKMWEQEEE--DKMQEQEEMMWEQEEKMQEQEEKMW 649
+ Q +++EQ ++ K+ + E +Q ++ + E +K+ E +EK+
Sbjct: 533 TTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLS 592
Query: 650 EQEE--KMREQE-EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
E +E +++ QE + +++Q ++ G ++ +++ ++E + Q +++
Sbjct: 593 ELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQL-- 650
Query: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQE 740
Q+++ G+ ++E++E +ER+ ++ Q+
Sbjct: 651 QQQEAQGKAVAEMARQELQETQERLEAATQQNQQ 684
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 295 bits (754), Expect = 2e-79
Identities = 194/665 (29%), Positives = 386/665 (58%), Gaps = 69/665 (10%)
Query: 143 LQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESE 202
LQ+ L + ++ + E+L K + LE R + LK++ E +++L E E
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR---EQRLKREQEERRDQLLKREEE 584
Query: 203 KSEIQLNVKELKRKLERAKFL-LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 261
+ + +L ++ +R +R K + +++ +E+ ++EE E+ +++ K EE+ R++
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 262 ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK--- 318
++LR ++ + REQ K +E+RL ++ K RE E+E REQ+ E++EQ +E+ +
Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQRLK--REHEEERREQELAEEEQEQARERIKSRIP 702
Query: 319 --MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL---REKEE 373
W+ E + ++ K++ + + Q ++ ++E++ R + E W+++ER +++EE
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 374 RMREQEKMWEQEEKMQEEER-------IRE-REKKMREEEETMREQ----EEKMQKQEEN 421
+ R+ W+ EEK + + +RE RE+++R EE REQ EE+ ++Q
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
Query: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM------WGQEKKM 475
+ EKE Q EQ ++ +++QE+E+ + E +E+ R QE+ W E++
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
Query: 476 WR-----------QEKMREQEDQMWEQEEKMR--DQEQKMWDQEERMWEQDERLREKEER 522
R QE++R+++ + E+EE+++ ++E++ ++ER + ++E+L+++EE+
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 523 M----REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
+ RE+++ ++E + R++KK Q++E++ +E E+ R +EREKK REEEE+ +E
Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP---EKRRRQEREKKYREEEELQQE 999
Query: 579 QEEKMQEQEEKMREQE---------EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629
+E+ ++E+ EK R QE E E+E+ ++E+ EK QE + +EEE+ QE
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
Query: 630 QEEMMWEQEEKMQEQE-EKMWEQEEKMREQEEK-MREQEEK--MQGQEEKMREQEEKMQG 685
+E+++ E+ E + QE E+ + +EE+++++EE+ +RE+ EK Q +E + RE+EE Q
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 686 QEEKMREQEEKMRGQE-EKMWGQEEKMWGQEEKMWGQE-EMREKEERIRDQKEKMQERLP 743
+E+ +RE+ EK R QE E+ + +EE++ +EE++ +E E R ++E R +E +E L
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE--EEELQ 1177
Query: 744 EHEER 748
+ EE+
Sbjct: 1178 QEEEQ 1182
Score = 293 bits (749), Expect = 6e-79
Identities = 212/751 (28%), Positives = 419/751 (55%), Gaps = 90/751 (11%)
Query: 69 PEDEKKASHQHQEALR-REIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESK 127
PE+E+K + Q R +E++ + ++ Q+ E L +D ++ ++ + +
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQL---QRRERAQQLQEEEDGLQEDQERRRSQEQ 868
Query: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKK 187
R W + E +R + + K A + E+L KE+ L E + EE +K
Sbjct: 869 ----RRDQKWRWQLEEERKRRRHTLYAKPALQ--EQLRKEQQLLQEE--EEELQREEREK 920
Query: 188 KNAELQEKLRLAES----EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 243
+ + QE+ E E+ ++ +E +R+ ER + + +E++ +E E
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Query: 244 R---EQEKKIRKQEEKMWRQEERLREQEGKMREQE-EKMRRQEKRLREQEKELREQEKEL 299
R E+EKK R++EE +E+ LRE+ K R QE E+ R++ L+++E++L +E+E
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Query: 300 RE----QKKLREQEEQMQEQEEKMWEQEEKMREQE-EKMWRQEERLWEQEKQM------- 347
R +++ RE+EE QE+E+ + E+ E R QE E+ +R+EE L ++E+Q+
Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEK 1100
Query: 348 ---REQEQKMRDQEERMWEQDERLREKEERMR---------EQEKMWEQEEKMQEEE--- 392
+E+E++ R++EE E+++ LRE+ E+ R E+E++ ++EE++ EE
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160
Query: 393 -RIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW-QQQRLPEQKEKLWEQEKMQE 450
R +E E++ REEEE +E+E+ +++++E ++ E+++ +++ L QK K +++ Q
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Query: 451 QEEKIW----EQEEKIRDQEEMW-GQEKKMWRQ---EKMREQEDQ------MWEQEEKMR 496
+ K W E+E +RD + G+E + +RQ ++R+++ Q + EQ+E+ R
Sbjct: 1221 SDLK-WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR 1279
Query: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKM-----REEK-KTQEQEKKTW 550
+QE++ W Q +R + ++E+L +E++ +++ QEEK REEK + QE ++K
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
Query: 551 DQEEKMREEE----RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK----MWEQEE 602
++E+ ++E E R +ER++K REEE +EQ K E+E+++R QE + EQ+
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE---KMQEQEEKMWEQEEKMR-EQ 658
+ QE+E+++ + ++ + +EE+ +++ + + +EE + QE+E K E+E+++R E+
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 659 EEKMREQEEKMQGQEEKM---REQEEKMQGQEEKMREQE--EKMRGQEEKMWGQEEKMWG 713
K RE+E+ +Q +EE+ +E++ K +E+++R QE K R QE + E K
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 714 QEEKMWGQEEMR---EKEERIRDQKEKMQER 741
+E+++ Q+ R ++E+++R Q+ Q R
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Score = 286 bits (733), Expect = 4e-77
Identities = 219/780 (28%), Positives = 424/780 (54%), Gaps = 115/780 (14%)
Query: 73 KKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG- 131
++ + ++ LRRE E + ++ Q+ E L Q R+ + L + L
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ---LRREQQLRRE 410
Query: 132 -RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNA 190
+L E Q H++ ++ +E ++R E R+ + EE +++
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQ--KHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 191 ELQEKLRLAESEKSE-----IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
+ + K +L ++ E ++L +E + + ER + L + Q ++ + RQEEE R
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 246 Q-----EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Q E+++R+++E+ R+E+ L+ +E K EQE + +R ++ E+ +L ++E+E R
Sbjct: 529 QQRLRSEQQLRREQEE--RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 301 EQKKLREQEEQMQ--------------EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
+Q+ REQEE+++ E+ E+ ++EE E+ +++ + EE+ +++Q
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK------- 399
+R ++Q+ R+Q + E++ERL ++ +R E+E+ EQE +E+E+ RER K
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERR-EQELAEEEQEQARERIKSRIPKWQ 705
Query: 400 ------------------KMREEEETMREQEEKMQKQEENM-WEQEEKEWQQQRLPEQKE 440
+ +E + +EQEEK +++E + W++EE+ +QQ+ EQ+
Sbjct: 706 WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Query: 441 KL---WEQEKMQEQ---------------EEKIWEQEEKIRDQEEMWGQEKKMWR--QEK 480
W+ E+ E+ E ++ +E + R+Q + +E+K R Q +
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825
Query: 481 MREQEDQMWEQEEKM--RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
RE+E Q E+EE++ R++ Q++ ++E+ + E ER R +E+R R+QK WQ EE+ +
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR-RDQKWRWQLEEERKR 884
Query: 539 EKKT-------QEQEKKTW----DQEEKMREEERMR----EREKKMREEEEMMREQEEKM 583
+ T QEQ +K ++EE+++ EER + E+E++ REEE++ +E+E+ +
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 584 QEQEEKMREQE-EKMWEQEEKMQEQEEK-MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM 641
+E+ EK R QE E+ + +++K+Q++EE+ + E+ EK QE E K +E+EE+ E+E+ +
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 642 QEQEEKM----WE-----QEEKMREQEEKMREQEEK--MQGQEEKMREQEEKMQGQEEKM 690
+E+ EK WE ++E +E+E+ +RE+ EK +Q +E + RE+EE Q +E+ +
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 691 REQEEKMRGQE-EKMWGQEEKMWGQEEKMWGQE-EMREKEERIRDQKEKMQERLPEHEER 748
E+ E R QE E+ + +EE++ +EE++ +E E R ++ER R +E +E L + EE+
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE--EEELQQEEEQ 1122
Score = 286 bits (732), Expect = 5e-77
Identities = 180/628 (28%), Positives = 376/628 (59%), Gaps = 94/628 (14%)
Query: 202 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 261
E+ E QL +E +++ +R LP+ + ++E R++ RE+E + ++EE++ R+E
Sbjct: 792 EQRERQLRAEERQQREQR---FLPEEE----EKEQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 262 --ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE---------QKKLREQEE 310
++L+E+E ++E +E+ R QE+R ++ + E+E++ R Q++LR++++
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 311 QMQEQEEKMW--EQEEKMREQEEKMWRQEERLWEQEKQM--REQEQKMRDQEERMWEQDE 366
+QE+EE++ E+E++ R+++E+ +R+EE+L ++E+Q+ E+E++ R + ER + +D+
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
Query: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
+L++KEE++ +E E+ + + E++ RE E+ +EEE+ +RE+ EK ++QE ++
Sbjct: 965 KLQQKEEQLLGEEP--EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 427 EKEWQQ---QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-- 481
+ E QQ Q L E++EK ++QE+E + E+EE +++E++ G+E++ R++++
Sbjct: 1023 KDELQQEEEQLLREEREK----RRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 482 --REQEDQMWEQEEKMRDQEQKMWDQE-ERMWEQDERLREKEERM----REQKKMWQQEE 534
R++E+ E+E+ +R++ +K QE ER ++E L+++EE++ RE+++ + E
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
+ REE++ Q++E++ +E E+ R +E E++ REEEE+ +E+E+ ++E++EK R++
Sbjct: 1139 QYREEEEVQQEEEQLLREEP---EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 595 EKMWEQEEKMQEQEEKMWEQEEK-------MWEQEEED---------------------- 625
E+ + +EE++Q Q+ K ++E WE E+E+
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
Query: 626 -------KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK------MQGQ 672
Q+ + ++ EQ+E+ +EQE + W+Q ++ +EE++ +E+K + Q
Sbjct: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
Query: 673 EEKM-----REQEEKMQGQEEKMREQEEKMRGQEEK-MWGQEEKMWGQEEKMWGQEEMR- 725
EEK RE++ + Q + K RE+E+ ++ +EE+ + QE +EE++ QE+ R
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
Query: 726 --EKEERIRDQKEKMQERLPEHEERCSE 751
E+E+R+R Q+ + + E + RC E
Sbjct: 1376 FLEEEQRLRRQERERKFLKEEQQLRCQE 1403
Score = 285 bits (730), Expect = 9e-77
Identities = 198/652 (30%), Positives = 376/652 (57%), Gaps = 91/652 (13%)
Query: 174 ELYRNTITNEELKKKNAELQEKL-----RLAESEKSEIQLNVKELKRKLERAKFLLPQVQ 228
+L R E + K E +E+L R E E+ E +L +E ++ ER K +P+ Q
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705
Query: 229 ------TNTLQEEMW----RQEEELREQE---KKIRKQEEKMWRQEERLREQEGKMREQ- 274
+ Q +++ +QE + R QE K+ R++ E W++EER Q+ + ++
Sbjct: 706 WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Query: 275 --------EEKMRRQEKRL------REQ-EKELREQEKELREQKKLREQEEQMQ------ 313
EEK R +RL REQ E++LR +E++ REQ+ L E+EE+ Q
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825
Query: 314 --EQEEKMWEQEEKM--REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 369
E+E + E+EE++ RE+ +++ +E+ L E +++ R QEQ+ RDQ+ R ++ER R
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR-RDQKWRWQLEEERKR 884
Query: 370 EK----------EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
+ E+ +EQ+ + E+EE++Q EER EK+ R+E+E +EE++Q++E
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREER----EKRRRQEQERQYREEEQLQQEE 940
Query: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
E + +E ++ ++Q Q K +++ Q++E+ + E+ EK R QE R++
Sbjct: 941 EQLLREEREKRRRQERERQYRK--DKKLQQKEEQLLGEEPEKRRRQE----------REK 988
Query: 480 KMREQEDQMWEQEEKMRDQEQKMWDQE-ERMWEQDERLREKEERM----REQKKMWQQEE 534
K RE+E+ E+E+ +R++ +K QE ER + + + L+++EE++ RE++++ ++E
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
Query: 535 KMREEKKTQEQEKKTWDQEEKMRE----EERMREREKKMREEEEMMREQEEKM--QEQEE 588
+ REE++ Q++E++ +E + R E + R+ E+ +EEE+++RE+ EK QE+E
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE-EK 647
+ RE+EE E+E+ ++E+ EK QE + +EEE+ QE+E+++ E+ EK + QE E+
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
Query: 648 MWEQEEKMREQEEK-MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
+ +EE+++++EE+ +RE++EK + + E+ +EE++Q Q+ K R ++E R + W
Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWE 1228
Query: 707 QEEKMWGQEEKMW--GQE-----EMREKEERIRDQKEKMQERLPEHEERCSE 751
E++ ++ K++ G+E ++ + + R R ++ +Q L E +ER E
Sbjct: 1229 PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE 1280
Score = 278 bits (710), Expect = 2e-74
Identities = 215/777 (27%), Positives = 423/777 (54%), Gaps = 103/777 (13%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETA----LYYSQDAARKFEDGNLGE 125
E EK+ + + R++ E Q ++L ++ + Y ++ ++ E+ LGE
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 126 SKDLAGR--LHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNE 183
++ R L + ELQ+ + + R E + R+ L+ + E
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Query: 184 EL-KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
E K++ EL+ + R E+ E+Q ++L R+ E K +++ +EE +QEEE
Sbjct: 1127 EREKRRRQELERQYR----EEEEVQQEEEQLLRE-EPEKRRRQELERQYREEEELQQEEE 1181
Query: 243 --LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL- 299
LRE+++K R++ E+ +R+EE L+ Q+ K R ++E R K E EKE ++ ++
Sbjct: 1182 QLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVY 1241
Query: 300 ---REQKKLREQEEQM-------QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 349
RE ++ R+ E+ Q+ + + EQ+E+ REQE + W+Q +R + +E+Q+
Sbjct: 1242 CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Query: 350 QEQKMRDQEERMWEQDERL--REKEERMREQE---KMWEQEEKMQEEE----RIREREKK 400
+EQK + +R +++++L E+EE+ R QE K E+E+ +QE E R +ER++K
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 401 MREEEETMREQEEKMQKQEENMWEQEE-----KEWQQQRLPEQKEKLWE----------- 444
REEE +EQ K ++E+ + QE KE QQ R E++++L +
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 445 QEKMQEQEEKIWEQEEKIRDQEE--MWGQEKKMWRQE---KMREQEDQMWEQEEKM---R 496
Q QE++ K E+E+++R QE + +E++ RQE K RE+E + E+EE+ +
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Query: 497 DQEQKMWDQEE--RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
++++K ++E+ R E+D + RE+E R +E ++ + +EE ++ Q++++K +E+
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE---QQLHRQQRQRKFLQEEQ 1538
Query: 555 KMREEER----MREREKKMREEEEMMREQEEKM-------------------QEQEEKMR 591
++R +ER ++R++K REEE++ +E+EE+ QEQE K
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFM 1598
Query: 592 EQEEKMWEQE--EKMQEQEEKMWEQEEKMWEQEEEDKM--QEQEEMMWEQEEKMQEQEEK 647
E E+++ QE ++++++ ++ + ++E++ ++ EE ++ QE++ E+E +++ QE +
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE 1658
Query: 648 M---WEQEEKMREQEEKMREQEE---KMQGQEEKMREQEEKM--QGQEEKMREQEEKMRG 699
+++ K RE+E+ ++E EE + Q ++ K RE+E+++ Q +E K ++E+++R
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRR 1718
Query: 700 QEEKMWGQEEKMWGQE---EKMWGQEEMRE--KEERIRDQKEKMQERLPEHEERCSE 751
QE + +EE+ QE E++ QE R+ +EE++R ++E+ Q R E + + E
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Score = 275 bits (703), Expect = 1e-73
Identities = 193/640 (30%), Positives = 372/640 (58%), Gaps = 75/640 (11%)
Query: 153 WHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKS---EIQLN 209
W ++ + EE ER+ R+ + EE + E +EK R E+++ E QL
Sbjct: 1286 WQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLL 1345
Query: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR---EQEKKIRKQEE--KMWRQEERL 264
+ ++ L R Q + +EE R +E+ R E+E+++R+QE K ++E++L
Sbjct: 1346 QEREEQPLRR------QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 265 REQEG----------KMREQEEKMRRQEK--RLREQEKELREQEKELREQKKLREQEEQM 312
R QE K RE+E+++ RQE+ + RE+E+++R QE RE+K L E+++
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE---RERKFLEEEQQLR 1456
Query: 313 QEQEEKMWEQEEKMREQEEKMWRQEER---LWEQEKQMREQEQ--KMRDQEERMWEQDER 367
QE+ K E+E+ ++E+EE+ ++ER E+E+Q+R QE+ K R+QE R E + +
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Query: 368 LREKEERMREQEKMWEQEEKMQEEERIREREK---KMREEEETMREQEEKMQKQEENMWE 424
E+E+++ Q++ Q + +QEE+++R +E+ + ++ + RE+E+ Q++EE
Sbjct: 1517 FLEEEQQLHRQQR---QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLS 1573
Query: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
++E++ ++ RL EQK + QEQE K E E+++R QE Q+ + R K RE
Sbjct: 1574 RQERD-RKFRLEEQKVR------RQEQERKFMEDEQQLRRQEGQ--QQLRQERDRKFRED 1624
Query: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT-- 542
E + E+EE+ ++++ + + E++ +LR +E REQ+ ++ K REE++
Sbjct: 1625 EQLLQEREEQQLHRQER----DRKFLEEEPQLRRQE---REQQLRHDRDRKFREEEQLLQ 1677
Query: 543 --QEQEKKTWDQEEKMREEE---RMREREKKMREEEEMMREQE--EKMQEQEEKMREQEE 595
+EQ+ + +++ K REEE R +ERE+K +EE+ +R QE K +E+E+ +E E+
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
Query: 596 KMWEQEE---KMQEQEEKMWEQEEKMWEQEEED-KMQEQEEMMWEQEEKM--QEQEEKMW 649
+ ++E K+ E+E+ E+EE+ ++E D K +E+E++ E+EE+ ++ ++ +
Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
Query: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG-QEEKMWGQE 708
+EE++R++ E EQ+ + Q ++ K R +EE++Q +E++ R ++E+ R + E+ + +
Sbjct: 1798 REEEQLRQERE---EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ 1854
Query: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
EK +E+++W +EE + ++ER R +E+ R + E+R
Sbjct: 1855 EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Score = 275 bits (702), Expect = 2e-73
Identities = 198/633 (31%), Positives = 372/633 (58%), Gaps = 68/633 (10%)
Query: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
EE + R+ L EL R EE +++ E Q+++ E E+ E + L+++ E+ +
Sbjct: 207 EEQLRRRELL--ELRRKG--REEKQQQRRERQDRV-FQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 222 FLLPQVQTNTLQEEMWRQEEELREQEKK-IRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
PQ Q E+ +EE+LR+ E++ +R++ ++ +Q++RLR ++ R+QEE+ R
Sbjct: 262 EEEPQ-----RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316
Query: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
Q++ REQ+ E REQ++E REQ+ REQEE+ ++Q + EQEE+ REQ+ + ++EER
Sbjct: 317 QQEERREQQ-ERREQQEERREQQLRREQEERREQQLRR--EQEEERREQQLRREQEEERR 373
Query: 341 WEQ---EKQMREQEQKMRDQE---ERMWEQDERLREKEERMREQEKMWEQE-EKMQEEER 393
+Q E+Q+R ++Q R+Q+ E+ ++++LR +++ REQ+ EQ+ + QEEER
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Query: 394 IREREKKMREEEETMREQEEK---MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
++ ++ R E+ REQEE+ ++++EE ++E+ QQ + +++E+ K++E
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE 493
Query: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
+E + EQ+E+ R+Q+ QE++ ++ K +E+E+++ ++++R ++Q +QEER
Sbjct: 494 EERR--EQQER-REQQLRREQEERREQRLKRQEEEERL---QQRLRSEQQLRREQEER-- 545
Query: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQ--EQEKKTWDQEEKMREEERMRE---R 565
+++ L+ +EE+ EQ++ Q+ ++ +EE++ Q ++E++ Q K +EER+ + R
Sbjct: 546 -REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--EEKMWEQEEKMWEQEE 623
E+ R E+E REQ K +E EE+ R+Q K EQEE+ Q+Q E+ +E+++ +EE
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Query: 624 EDKMQ-----EQEEMMWEQEEKMQEQEEK-----------MWEQEEKMREQEEKMREQEE 667
E++++ E EE EQE +EQE+ W+ E + ++ K+ +
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 668 KMQG------QEEKMREQEEKMQGQEEK---MREQEEKMRGQEEKMWGQEEKMWGQEEKM 718
K +G QEEK R +E ++Q QEE+ ++QEE+ R W EEK +++
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784
Query: 719 WGQ---EEMREKEERIRDQKEKMQERLPEHEER 748
+ E RE++ R +++++ Q LPE EE+
Sbjct: 785 SARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
Score = 274 bits (701), Expect = 2e-73
Identities = 228/770 (29%), Positives = 403/770 (52%), Gaps = 108/770 (14%)
Query: 69 PEDEKKASHQHQEALRREIEAQ-DHTIRILTCQKTELETALYYSQDAARKFEDGNLGESK 127
P ++ Q QE E E Q + R+ + + L+ + ++ E+ E +
Sbjct: 133 PGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ 192
Query: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKER--------DALSLELYRNT 179
+ + H + F E Q + +K ++ +ER +
Sbjct: 193 LQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239
+ EE K + E Q + L E E+ +L +EL+R ER + Q + Q+ +Q
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR--ERQEEEQQQQRLRREQQLRRKQ 310
Query: 240 EEELREQEKKIRKQEEKMWRQEERLREQ---------EGKMREQEEKMRRQEKRLREQEK 290
EEE REQ+++ R+Q+E+ +QEER +Q E ++R ++E+ RR+++ REQE+
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 291 ELREQ----------EKELREQKKLREQEEQMQEQE---EKMWEQEEKMREQEEKMWRQE 337
E REQ E++LR +++LR +++ +EQ+ E+ +E+++R +++ QE
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 338 ERLWEQ--EKQMREQEQKMRDQEERMW--EQDERLREKEERMREQEKMWEQEE------K 387
E EQ E++ REQ K +E R W ++E R ++ER ++Q K ++EE K
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 447
++EEER RE++ R E++ REQEE ++E+ + QEE+E QQRL +++ EQE+
Sbjct: 491 LEEEER---REQQERREQQLRREQEE---RREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507
+EQ K +EEK +QE +E+++ R+++ E+ DQ+ ++EE+ R Q K +QEE
Sbjct: 545 RREQLLK--REEEKRLEQER---REQRLKREQE--ERRDQLLKREEERRQQRLKR-EQEE 596
Query: 508 RM-----WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ---EEKMREE 559
R+ E+ ERL ++E R + K+ +EE+ ++ K++EQE++ Q E++ R E
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Query: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK-----------MWEQEEKMQEQE 608
+R++ E++ R E+ + RE EE+ +EQE EQE+ W+ E + ++
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716
Query: 609 EKMW----EQEEKMWEQEEEDKMQEQE-EMMWEQEEK--MQEQEEK-------MWEQEEK 654
K++ +QE + QE+E+K + +E E+ W++EE+ Q+QEE+ W+ EEK
Sbjct: 717 SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
Query: 655 -------------MREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM-REQEEKMRGQ 700
+REQ E+ EE+ Q ++ + E+EEK Q + ++ RE+E + +
Sbjct: 777 SERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Query: 701 EEKMWGQEEKMWGQEEKMWGQE--EMREKEERIRDQKEKMQERLPEHEER 748
EE++ +E QEE+ QE E R +E+ RDQK + Q L E +R
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQ--LEEERKR 884
Score = 271 bits (692), Expect = 2e-72
Identities = 197/630 (31%), Positives = 363/630 (57%), Gaps = 82/630 (13%)
Query: 161 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLR-LAESEKSEIQLNVKELKRKLER 219
+++ +E D E + E +++ + QE+ R LAE E E K ER
Sbjct: 110 LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE---------EQSEKQER 160
Query: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM----------WRQEERLREQE- 268
L Q EE+WRQ +E +E+E++ R +EE++ + EE+LR +E
Sbjct: 161 ----LEQRDRQRRDEELWRQRQEWQEREER-RAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 269 ------GKMREQEEKMRRQEKRLR-EQEKELREQEKELR-EQKKLREQEEQMQEQEEKMW 320
G+ +Q+++ RQ++ + E+EKE R++E LR E++KL+E+E Q Q + ++
Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
Query: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380
EQ K+ QE + RQEE +Q++++R ++Q R QEE EQ E RE++ER +QE+
Sbjct: 276 EQLRKLERQELRRERQEEE--QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
EQ+ + ++EER RE+++R E+E R +++ ++QEE EQ+ + QQ R +Q
Sbjct: 334 RREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
Query: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ--EEKMRDQ 498
+ EQ+ +EQ+ + +E+++R ++++ +++ Q+ REQE++ EQ E++ R+Q
Sbjct: 391 R--EQQLRREQQLR---REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 499 EQKMWDQEERMW--EQDERLREKEERMREQKKMWQQEE------KMREEKKTQEQEKKTW 550
K +E R W ++E R ++ER ++Q K Q+EE K+ EE++ ++QE++
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR-- 503
Query: 551 DQEEKMREEERMREREKKMREEEEMMREQ---EEKMQEQEEKMREQ-----EEKMWEQEE 602
+++ RE+E RE+ K +EEEE ++++ E++++ ++E+ REQ EEK EQE
Sbjct: 504 -EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQ----EQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658
+ Q + + E+ +++ ++EEE + Q EQEE + E++++ +E + EQEE+ REQ
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERL---EQRLKREEVERLEQEER-REQ 618
Query: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQ----EEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
K E EE+ + Q K EQEE+ Q Q +++ REQ K +EE++ E+++ +
Sbjct: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL---EQRLKRE 675
Query: 715 EEKMWGQEEMREKEERIRDQKEKMQERLPE 744
E+ ++E+ E+E+ +E+++ R+P+
Sbjct: 676 HEEERREQELAEEEQ--EQARERIKSRIPK 703
Score = 270 bits (689), Expect = 5e-72
Identities = 228/816 (27%), Positives = 417/816 (51%), Gaps = 103/816 (12%)
Query: 15 EKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTT---SEGCHSPED 71
E+ R+ +L E ++K + +Q R +++K ET E E
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK--EWRKRETVLRKEEEKLQEEEP 265
Query: 72 EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG 131
+++ Q +E R++E Q+ +R ++ + + L Q RK E+ + ++
Sbjct: 266 QRQRELQEEEEQLRKLERQE--LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 132 RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAE 191
+ E Q ++ +R ++L +E++ E EE +++
Sbjct: 324 QQERR-----EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 192 LQEKLRLAESEKSEIQLNVKELKRK---LERAKFLLPQVQTNTLQEEMWRQEEELREQEK 248
+++LR + + E QL ++ R+ L R + L + Q Q+ QEEE EQ+
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Query: 249 KIRKQEEKMWRQEERLRE--QEGKMREQEEKMRRQEKRLREQEKELRE-----QEKELRE 301
+ ++E+++ R++E R+ + + E+ E+ RR+++ R+QE+E RE +E+E RE
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 302 QKKLREQE-----EQMQEQEEKMWEQEEKM-----------REQEEK----MWRQEERLW 341
Q++ REQ+ E+ +EQ K E+EE++ REQEE+ + R+EE+
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 342 EQEKQMREQEQKMRDQEERMWEQDERLREKEERM-----REQEKMWEQEEKMQEEERIRE 396
EQE+ REQ K R+QEER +D+ L+ +EER REQE+ EQ K +E ER+ +
Sbjct: 559 EQER--REQRLK-REQEER---RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
E R E+ RE+ E+ ++Q+ E++E+ QQQ EQ+E+ ++ K +E+EE++
Sbjct: 613 EE---RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL- 668
Query: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ-----MWEQEEKMRDQEQKMWDQEERMWE 511
EQ K +EE QE QE+ RE+ W+ E + ++ K++ + +
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
Query: 512 QDERLREKEERMREQKKM-WQQEEKMREEKKTQEQEKK-TWD-QEEKMREEERMR----- 563
Q R ++E+R R + ++ WQ+EE+ +++ +EQ + TW Q E+ E R R
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 564 ----EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
+RE+++R EE REQ +E+E++ R ++ + E+E + E+EE++ +E
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---------------------EQ 658
QEEED +QE +E QE++ ++ E+E K R ++
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 659 EEKMREQEE----KMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE-EKMWGQEEKMWG 713
EE+ ++EE + Q QE + RE+E+ Q +E+ +RE+ EK R QE E+ + +++K+
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 714 QEEKMWGQE-EMREKEERIRDQKEKMQERLPEHEER 748
+EE++ G+E E R ++E R++K + +E L + EE+
Sbjct: 969 KEEQLLGEEPEKRRRQE--REKKYREEEELQQEEEQ 1002
Score = 261 bits (666), Expect = 2e-69
Identities = 168/596 (28%), Positives = 352/596 (59%), Gaps = 36/596 (6%)
Query: 183 EELKKKNAELQEKL---RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239
+E K+ + +E L R E ++ + ++L+ + + + Q Q L E +
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
Query: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
E++ R +++ ++++E++WRQ + +E+E + E+E+ + E E + + +EL
Sbjct: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
E ++ +E+Q Q +E Q+ +E+EEK WR+ E + +E++ ++E+ R +E
Sbjct: 216 LELRRKGREEKQQQRRER----QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
Query: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQ 418
+ E+ R E++E RE+++ +Q+++++ E+++ R++E++ RE++E REQ+E+ ++Q
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331
Query: 419 EENMWEQ----EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
EE +Q +E+ +QQ EQ+E+ EQ+ +EQEE+ +E+++R ++++ +++
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE--RREQQLRREQQLRREQQL 389
Query: 475 MWRQEKMREQE---DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Q+ REQ+ +Q +E+++R ++Q +Q+ R +++ER +K E+ R ++++ +
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Query: 532 QEEKMRE----EKKTQEQEKKTWDQEEKMREEERMREREKKMREEE--EMMREQEEKMQE 585
++E+ R+ E++T+ E++ Q+ K +EE RER K+ EEE E +E++++
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 586 QEEKMREQEEKMWEQEEKMQEQ---EEKMWEQEEKMWEQ---EEEDKMQEQEEMMWEQEE 639
++E+ REQ K E+EE++Q++ E+++ ++E+ EQ EE+K EQE +
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 640 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQ---GQEEKMREQEEKMQGQEEKMREQEEK 696
+ +E+ +++ ++EE+ R+Q K REQEE+++ +EE R ++E+ + Q K E EE+
Sbjct: 570 EQEERRDQLLKREEERRQQRLK-REQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 697 MRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLP-EHEERCSE 751
R Q K QEE+ Q++ Q+E RE+ + +++E++++RL EHEE E
Sbjct: 629 RRQQLLKSEEQEERR--QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682
Score = 204 bits (520), Expect = 2e-52
Identities = 175/627 (27%), Positives = 325/627 (51%), Gaps = 87/627 (13%)
Query: 67 HSPEDEKKASHQHQEALRREIEAQDHTI-----------RILTCQKTELETALYYS---- 111
H PE+E+ + +EA RR+ ++Q+ R T +K E L
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQ 1351
Query: 112 ----QDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKE 167
Q+ RKF + L + L + + + ++L ++
Sbjct: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQD 1411
Query: 168 RDALSLELYRNTITNEELKKKNAELQEKLRLAESEKS---EIQLNVKELKRKLERAKFLL 224
RD E ++ +E +K E ++++R E E+ E Q +E RK + LL
Sbjct: 1412 RDRKFRE-EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLL 1470
Query: 225 PQVQTNTLQEEMWRQEEELR--EQEKKIRKQEE--KMWRQEERLREQEGKMREQEEKMRR 280
+ + ++++ RQE + + E+E+++R+QE K QE R +E E K E+E+++ R
Sbjct: 1471 QERE----EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 281 QEKRLR--EQEKELREQEK-ELREQ---KKLREQEEQMQEQEEKMWEQEE---KMREQEE 331
Q+++ + ++E++LR QE+ + R Q +K RE+E+ QE+EE+ ++E K R +E+
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 332 KMWRQEE--RLWEQEKQMREQE--QKMRDQEERMWEQDERL-REKEE----RMREQEKMW 382
K+ RQE+ + E E+Q+R QE Q++R + +R + +DE+L +E+EE R K
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL 1646
Query: 383 EQEEKMQEEERIRE----REKKMREEEETM-----------------REQEEKMQKQE-E 420
E+E +++ +ER ++ R++K REEE+ + RE+E+++++QE E
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Query: 421 NMWEQEEKEWQQQRL------PEQKEKLWEQEKMQEQE--EKIWEQEEKIRDQEEMWGQE 472
+ QEE++ ++Q L EQ + EQE+++ QE KI E+E+ ++EE Q
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ--QL 1764
Query: 473 KKMWRQEKMREQEDQMWEQEE-KMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
++ R K RE+E E+EE ++R QE +EE Q+ ++ + R+ K W+
Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824
Query: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK-MQEQEEKM 590
+E+ EE ++++ +++ + R EE+ +EK REE+E+ +E+E+K QE+E K+
Sbjct: 1825 EEQLQLEE----QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
Query: 591 REQEEKMWEQEEKMQEQEEKMWEQEEK 617
RE+ + ++EE+ Q ++ QE K
Sbjct: 1881 REEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 162 bits (409), Expect = 2e-39
Identities = 101/377 (26%), Positives = 219/377 (58%), Gaps = 36/377 (9%)
Query: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443
Q + EE+R R K+ ++ E + + + ++ + E+E + ++Q+ EQ+ +L
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQL-EEEPGQRRRQKRQEQERELA 149
Query: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
E E+ E++E++ EQ ++ R EE+W Q ++ +E+ R +E+Q+ Q
Sbjct: 150 EGEEQSEKQERL-EQRDRQRRDEELWRQRQEWQEREERRAEEEQL-----------QSCK 197
Query: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
E + +E+LR +E + + K REEK+ Q +E++ D+ + EE+ R
Sbjct: 198 GHETEEFPDEEQLRRRE--------LLELRRKGREEKQQQRRERQ--DRVFQEEEEKEWR 247
Query: 564 EREKKMREEEEMMREQE----EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
+RE +R+EEE ++E+E ++QE+EE++R+ E + +E + +EQ+++ +E+++
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ---EEKMREQEEKMREQEEKMQGQEEKM 676
++EE++ ++QEE EQ+E+ ++QEE+ +Q E++ R +++ REQEE+ + Q+ +
Sbjct: 308 RKQEEERREQQEERR-EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 677 REQEEKMQGQ---EEKMREQEEKMRGQEEKMWGQ--EEKMWGQEEKMWGQEEMREKEERI 731
++EE+ + Q E+++R +++ R Q+ + Q E+ +E+++ ++++R +++
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 732 RDQKEKMQERLPEHEER 748
R+Q+E+ E+ E E R
Sbjct: 427 REQEEERHEQKHEQERR 443
Score = 60.5 bits (145), Expect = 6e-09
Identities = 40/169 (23%), Positives = 89/169 (52%), Gaps = 13/169 (7%)
Query: 587 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
EEK + K +++ QE++++ +E ++ E+E + + +K QEQE
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQR----------RRQKRQEQER 146
Query: 647 KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE-EKMRGQEEKMW 705
++ E EE+ +QE EQ ++ + EE R+++E + +E + E++ + +G E + +
Sbjct: 147 ELAEGEEQSEKQERL--EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 706 GQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCL 754
EE++ +E ++ EK+++ R++++++ + E E R E L
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 249 bits (636), Expect = 7e-66
Identities = 168/503 (33%), Positives = 282/503 (56%), Gaps = 82/503 (16%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP+LPPHPMM E++RQNKLA AKKK +Y+Q G+ A TKKKK ++ +PET
Sbjct: 1 MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAK-TKKKKTDS--SPET 57
Query: 61 TTSEGCHSPED------------------------------EKKASHQHQEALRREIEAQ 90
TTS GCHSP D +K+ HQ +EA + E
Sbjct: 58 TTSGGCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIH 117
Query: 91 D------HTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQ 144
TI ILT +K +L+T LY+++ AAR FE+ ESKDLAGRL +S EL+
Sbjct: 118 KAQMERLETINILTLEKADLKTTLYHTKRAARHFEE----ESKDLAGRLQYSLQRIQELE 173
Query: 145 RALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNA-ELQEKLRLAESEK 203
RAL AVST ++ DR + R+A+ + TI L + ++ E L+ + E+
Sbjct: 174 RALCAVSTQQQEEDRS----SSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLER 229
Query: 204 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE--------- 254
E ++K + + + + + V+ TL+EE R ++E E+ + + +
Sbjct: 230 DEYAKHIKGERARWQERMWKM-SVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSL 288
Query: 255 ---------EKMWRQEERLREQ----EGKMREQEEK-------MRRQEKRLREQEKELRE 294
E++ + + LR++ EGK++ Q E + Q++RL+EQE+ LRE
Sbjct: 289 APPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLRE 348
Query: 295 QEKE-LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
QE + +REQ++L EQ E+++EQ++ + EQ E++R+QE+++ +QEERL ++E+++++QE++
Sbjct: 349 QEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 354 MRDQEERMWEQDERLREKEER--MREQEKMWEQ-EEKMQEEERIREREKKMREEEETMRE 410
+ DQEER+W+++ERL+++EER + + K+ +Q E E + +K + E+ ++E
Sbjct: 409 LWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKE 468
Query: 411 QEEKMQKQEENMWEQEEKEWQQQ 433
+EK+ ++ + ++ + Q
Sbjct: 469 LQEKLDEEHLEAASHQNQQLETQ 491
Score = 145 bits (365), Expect = 2e-34
Identities = 161/698 (23%), Positives = 307/698 (43%), Gaps = 148/698 (21%)
Query: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
KKK + + + S +EL LE + + Q+ N E + +Q++++
Sbjct: 47 KKKKTDSSPETTTSGGCHSPGDSQYQELAVALESSSVTISQLNENI--ESLKQQKKQVEH 104
Query: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ--- 302
Q ++ +K ++ + + E + ++ ++ + + E+ K+L +
Sbjct: 105 QLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQY 164
Query: 303 --KKLREQEEQM-----QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
++++E E + Q+QEE ++ RE + W Q+ + E+ Q
Sbjct: 165 SLQRIQELERALCAVSTQQQEE---DRSSSCREAVLQRWLQQT-IKERALLNAHVTQVTE 220
Query: 356 DQEERMWEQDERLRE-KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK 414
++ E+DE + K ER R QE+MW KM E R + EKK + R QE
Sbjct: 221 SLKQVQLERDEYAKHIKGERARWQERMW----KMSVEARTLKEEKK----RDIHRIQE-- 270
Query: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
++ L E K ++ E + + E+++D E K
Sbjct: 271 ----------------LERSLSELKNQMAEPPSLAPPA--VTSVVEQLQD-------EAK 305
Query: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE-ERMREQKKMWQQE 533
RQE + E ++ Q E + +Q++R+ EQ+E LRE+E +R+REQ+++ +Q
Sbjct: 306 HLRQE-VEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQN 364
Query: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
E++RE++KT +++ ER+R++E+++R++EE +R++EE++Q+QE+++ +Q
Sbjct: 365 ERLREQQKTLQEQG------------ERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQ 412
Query: 594 EEKMWEQEEKMQEQEEKM-WEQEEKMWEQEEE-----DKMQEQEEMMWEQEEKMQEQEEK 647
EE++W++EE++Q+QEE++ Q K+ +Q E + + +++ + E++++E +EK
Sbjct: 413 EERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEK 472
Query: 648 MWEQE-EKMREQEEKMREQ-------------------EEKMQGQEEKMREQEEKMQGQE 687
+ E+ E Q +++ Q EE+ + E E +
Sbjct: 473 LDEEHLEAASHQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532
Query: 688 EKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE------------------ 729
M +EK G E+ E + G + + MRE
Sbjct: 533 SFMDLPKEKADGTEQV----ERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMED 588
Query: 730 --RIRDQKEKMQERLPEHEE-----------------RCSEPCLPPSK------------ 758
R+ ++E+M+ +L E +E P P+
Sbjct: 589 VIRLAQKEEEMKVKLLELQELVLPLVGNHEGHGKFLIAAQNPADEPTPGAPAPQELGAAG 648
Query: 759 ---VLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEIMQL 793
V +S +VEPA G A EGSP DNPT Q+I+QL
Sbjct: 649 EQDVFYEVSLDNNVEPAPGAAREGSPHDNPTVQQIVQL 686
Score = 136 bits (343), Expect = 7e-32
Identities = 112/479 (23%), Positives = 229/479 (47%), Gaps = 74/479 (15%)
Query: 291 ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
E Q K +KKL+E +++ + ++K + + + Q +E
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGCHSPGDSQYQEL 74
Query: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
+ + + +E + +++ ++ E E+ +K E + E+ T+ +
Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEK 134
Query: 411 QEEKMQ----KQEENMWEQEEKE------WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
+ K K+ +E+E K+ + QR+ E + L Q++E++ E
Sbjct: 135 ADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCRE 194
Query: 461 KIRDQEEMWGQEKKMWRQEKMREQ---EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
+ + W Q+ ++E+ + + E ++ + E+DE +
Sbjct: 195 AVLQR----------WLQQTIKERALLNAHVTQVTESLKQVQL----------ERDEYAK 234
Query: 518 E-KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
K ER R Q++MW KM E +T ++EKK R+ R++E E+ + E + M
Sbjct: 235 HIKGERARWQERMW----KMSVEARTLKEEKK--------RDIHRIQELERSLSELKNQM 282
Query: 577 REQE-----------EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
E E++Q++ + +R++ E + E K+Q Q E Q + +E++
Sbjct: 283 AEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGL---EGKLQSQVEN--NQALSLLSKEQKQ 337
Query: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
++QEQEEM+ EQE + ++E++ EQ E++REQ++ ++EQ E+++ QE+++R+QEE++
Sbjct: 338 RLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERL-- 395
Query: 686 QEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
R++EE+++ QE+++W QEE++W +EE++ QE E Q K+ ++L E
Sbjct: 396 -----RKEEERLQKQEKRLWDQEERLWKKEERLQKQE-----ERLALSQNHKLDKQLAE 444
Score = 84.0 bits (206), Expect = 5e-16
Identities = 66/248 (26%), Positives = 129/248 (52%), Gaps = 26/248 (10%)
Query: 125 ESKDLAGRLHHSWHFAGELQRALS---------------AVSTWHKKADRYIEELTKERD 169
E++ L H EL+R+LS AV++ ++ + L +E +
Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVE 312
Query: 170 ALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQT 229
L +L N+ L + E +K RL E E+ L +E +R E+ + +
Sbjct: 313 GLEGKLQSQVENNQALSLLSKE--QKQRLQEQEE---MLREQEAQRVREQERLCEQNERL 367
Query: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Q+ + Q E LR+QE+++RKQEE++ ++EERL++QE ++ +QEE++ ++E+RL++QE
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE 427
Query: 290 KELREQEKELREQKKLREQE---EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
+ L + + K+L E + E + +++ + E++++E +EK+ EE L Q
Sbjct: 428 ERLALSQNH-KLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASHQ 484
Query: 347 MREQEQKM 354
++ E ++
Sbjct: 485 NQQLETQL 492
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 248 bits (634), Expect = 1e-65
Identities = 170/503 (33%), Positives = 283/503 (56%), Gaps = 82/503 (16%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP+LPPHPMM E++RQNKLA AKKK +Y+Q G+ A TKKKK ++ +PET
Sbjct: 1 MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAK-TKKKKTDS--SPET 57
Query: 61 TTSEGCHSPED------------------------------EKKASHQHQEALRREIEA- 89
TTS G HSP D +K+ HQ +EA + E
Sbjct: 58 TTSGGGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIH 117
Query: 90 -----QDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQ 144
Q TI ILT +K +L+T LY+++ AAR FE+ ESKDLAGRL +S EL+
Sbjct: 118 KAQMEQLETINILTLEKADLKTTLYHTKRAARHFEE----ESKDLAGRLQYSLQRIQELE 173
Query: 145 RALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNA-ELQEKLRLAESEK 203
RALSAVST ++ DR + R+A+ + TI L + ++ E L+ + E+
Sbjct: 174 RALSAVSTQQQEEDRS----SSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLER 229
Query: 204 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE--------- 254
E ++K + + + + + V+ TL+EE R ++E E+ + + +
Sbjct: 230 DEYAKHIKGERARWQERMWKM-SVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSL 288
Query: 255 ---------EKMWRQEERLREQ----EGKMREQEEK-------MRRQEKRLREQEKELRE 294
E++ + + LR++ EGK++ Q E + Q++RL+EQE+ LRE
Sbjct: 289 APPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLRE 348
Query: 295 QEKE-LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
QE + +REQ++L EQ E+++EQ++ + EQ E++R+QE+++ +QEERL ++E+++++QE++
Sbjct: 349 QEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 354 MRDQEERMWEQDERLREKEER--MREQEKMWEQ-EEKMQEEERIREREKKMREEEETMRE 410
+ DQEER+W+++ERL+++EER + + K+ +Q E E + +K + E+ ++E
Sbjct: 409 LWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKE 468
Query: 411 QEEKMQKQEENMWEQEEKEWQQQ 433
+EK+ ++ Q ++ + Q
Sbjct: 469 LQEKLDEEHLEAASQRNQQLETQ 491
Score = 142 bits (358), Expect = 1e-33
Identities = 142/621 (22%), Positives = 284/621 (45%), Gaps = 118/621 (19%)
Query: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQ-------EQEEKMWEQ 322
++ E E +++Q+K++ Q +E ++ E+ K EQ E + + + ++
Sbjct: 87 QLNENIESLKQQKKQVEHQLEEAKKTNNEIH--KAQMEQLETINILTLEKADLKTTLYHT 144
Query: 323 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER--LREKEERMREQEK 380
+ R EE+ RL ++++E E+ + + E+D RE + R Q+
Sbjct: 145 KRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQQT 204
Query: 381 MWEQEEKMQEEERIREREKKMR-EEEETMREQEEKMQKQEENMWE--------QEEKEWQ 431
+ E+ ++ E K+++ E +E + + + + +E MW+ +EEK+
Sbjct: 205 IKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRD 264
Query: 432 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 491
R+ E + L E + + + + E E K RQE + E ++ Q
Sbjct: 265 IHRIQELERSLSELKNQMAEPPSL--APPAVTSVVEQLQDEAKHLRQE-VEGLEGKLQSQ 321
Query: 492 EEKMRDQEQKMWDQEERMWEQDERLREKE-ERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
E + +Q++R+ EQ+E LRE+E +R+REQ+++ +Q E++RE++KT +++
Sbjct: 322 VENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQG--- 378
Query: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
ER+R++E+++R++EE +R++EE++Q+QE+++ +QEE++W++EE++Q+QEE+
Sbjct: 379 ---------ERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429
Query: 611 M-WEQEEKMWEQEEE-----DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
+ Q K+ +Q E + + +++ + E++++E +EK+ E+ + Q + E
Sbjct: 430 LALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLE 489
Query: 665 QE-------------EKMQGQEEK-------MREQEEKMQGQEEKMREQEEKMRGQEEKM 704
+ + + +EE+ + E E + M +EK G E+
Sbjct: 490 TQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQV- 548
Query: 705 WGQEEKMWGQEEKMWGQEEMREKEE--------------------RIRDQKEKMQERLPE 744
E + G + + MRE R+ ++E+M+ +L E
Sbjct: 549 ---ERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLLE 605
Query: 745 HEERC-----------------------SEPCLPPSKVL---------CNMSHTGSVEPA 772
+E P P + L +S +VEPA
Sbjct: 606 LQELVLPLVGNHEGHGKFLIAAQNPADEPTPGAPAPQELGAAGEQDDFYEVSLDNNVEPA 665
Query: 773 GGEAGEGSPQDNPTAQEIMQL 793
G A EGSP DNP Q+I+QL
Sbjct: 666 PGAAREGSPHDNPPVQQIVQL 686
Score = 133 bits (334), Expect = 8e-31
Identities = 113/476 (23%), Positives = 227/476 (47%), Gaps = 68/476 (14%)
Query: 291 ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
E Q K +KKL+E +++ + ++K + + + Q +E
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQEL 74
Query: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
+ + + +E + +++ ++ E E+ +K E + E+ T+ +
Sbjct: 75 AVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEK 134
Query: 411 QEEKMQ----KQEENMWEQEEKE------WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
+ K K+ +E+E K+ + QR+ E + L Q++E++ E
Sbjct: 135 ADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEEDRSSSCRE 194
Query: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE-K 519
+ ++++ + K R + Q + Q Q E+DE + K
Sbjct: 195 AVL--------QRRLQQTIKERALLNAHVTQVTESLKQVQL---------ERDEYAKHIK 237
Query: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
ER R Q++MW KM E +T ++EKK R+ R++E E+ + E + M E
Sbjct: 238 GERARWQERMW----KMSVEARTLKEEKK--------RDIHRIQELERSLSELKNQMAEP 285
Query: 580 E-----------EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
E++Q++ + +R++ E + E K+Q Q E Q + +E++ ++Q
Sbjct: 286 PSLAPPAVTSVVEQLQDEAKHLRQEVEGL---EGKLQSQVEN--NQALSLLSKEQKQRLQ 340
Query: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
EQEEM+ EQE + ++E++ EQ E++REQ++ ++EQ E+++ QE+++R+QEE++
Sbjct: 341 EQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERL----- 395
Query: 689 KMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
R++EE+++ QE+++W QEE++W +EE++ QE E Q K+ ++L E
Sbjct: 396 --RKEEERLQKQEKRLWDQEERLWKKEERLQKQE-----ERLALSQNHKLDKQLAE 444
Score = 85.1 bits (209), Expect = 2e-16
Identities = 88/363 (24%), Positives = 163/363 (44%), Gaps = 45/363 (12%)
Query: 125 ESKDLAGRLHHSWHFAGELQRALS---------------AVSTWHKKADRYIEELTKERD 169
E++ L H EL+R+LS AV++ ++ + L +E +
Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVE 312
Query: 170 ALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQT 229
L +L N+ L + E +K RL E E+ L +E +R E+ + +
Sbjct: 313 GLEGKLQSQVENNQALSLLSKE--QKQRLQEQEE---MLREQEAQRVREQERLCEQNERL 367
Query: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Q+ + Q E LR+QE+++RKQEE++ ++EERL++QE ++ +QEE++ ++E+RL++QE
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE 427
Query: 290 KELREQEKELREQKKLREQE---EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
+ L + + K+L E + E + +++ + E++++E +EK+ + Q Q
Sbjct: 428 ERLALSQNH-KLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQ 486
Query: 347 MREQE-------------QKMRDQEERMWEQDERLREK-EERMREQEKMWEQEEKMQEEE 392
E + Q + +EE + E E R M +EK E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546
Query: 393 RIREREKKMREEE---ETMREQEEKMQKQ----EENMWEQEEKEWQQQRLPEQKEKLWEQ 445
++ RE + + MRE + Q E E+ Q+ E K KL E
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLLEL 606
Query: 446 EKM 448
+++
Sbjct: 607 QEL 609
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 247 bits (631), Expect = 3e-65
Identities = 169/503 (33%), Positives = 282/503 (56%), Gaps = 82/503 (16%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP+LPPHPMM E++RQNKLA AKKK +Y+Q G+ A TKKKK ++ +PET
Sbjct: 1 MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAK-TKKKKTDS--SPET 57
Query: 61 TTSEGCHSPED------------------------------EKKASHQHQEALRREIEA- 89
TTS G HSP D +K+ HQ +EA + E
Sbjct: 58 TTSGGGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIH 117
Query: 90 -----QDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQ 144
Q TI ILT +K +L+T LY+++ AAR FE+ ESKDLAGRL +S EL+
Sbjct: 118 KAQMEQLETINILTLEKADLKTTLYHTKRAARHFEE----ESKDLAGRLQYSLQHIQELE 173
Query: 145 RALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNA-ELQEKLRLAESEK 203
RAL AVST ++ DR + R+A+ + TI L + ++ E L+ + E+
Sbjct: 174 RALCAVSTQQQEEDRS----SSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLER 229
Query: 204 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE--------- 254
E ++K + + + + + V+ TL+EE R ++E E+ + + +
Sbjct: 230 DEYAKHIKGERARWQERMWKM-SVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSL 288
Query: 255 ---------EKMWRQEERLREQ----EGKMREQEEK-------MRRQEKRLREQEKELRE 294
E++ + + LR++ EGK++ Q E + Q++RL+EQE+ LRE
Sbjct: 289 APPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLRE 348
Query: 295 QEKE-LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
QE + +REQ++L EQ E+++EQ++ + EQ E++R+QE+++ +QEERL ++E+++++QE++
Sbjct: 349 QEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 354 MRDQEERMWEQDERLREKEER--MREQEKMWEQ-EEKMQEEERIREREKKMREEEETMRE 410
+ DQEER+W+++ERL+++EER + + K+ +Q E E + +K + E+ ++E
Sbjct: 409 LWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKE 468
Query: 411 QEEKMQKQEENMWEQEEKEWQQQ 433
+EK+ ++ Q ++ + Q
Sbjct: 469 LQEKLDEEHLEAASQRNQQLETQ 491
Score = 143 bits (361), Expect = 6e-34
Identities = 142/621 (22%), Positives = 284/621 (45%), Gaps = 118/621 (19%)
Query: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQ-------EQEEKMWEQ 322
++ E E +++Q+K++ Q +E ++ E+ K EQ E + + + ++
Sbjct: 87 QLNENIESLKQQKKQVEHQLEEAKKTNNEIH--KAQMEQLETINILTLEKADLKTTLYHT 144
Query: 323 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER--LREKEERMREQEK 380
+ R EE+ RL + ++E E+ + + E+D RE + R Q+
Sbjct: 145 KRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRLQQT 204
Query: 381 MWEQEEKMQEEERIREREKKMR-EEEETMREQEEKMQKQEENMWE--------QEEKEWQ 431
+ E+ ++ E K+++ E +E + + + + +E MW+ +EEK+
Sbjct: 205 IKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRD 264
Query: 432 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 491
R+ E + L E + + + + E E K RQE + E ++ Q
Sbjct: 265 IHRIQELERSLSELKNQMAEPPSL--APPAVTSVVEQLQDEAKHLRQE-VEGLEGKLQSQ 321
Query: 492 EEKMRDQEQKMWDQEERMWEQDERLREKE-ERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
E + +Q++R+ EQ+E LRE+E +R+REQ+++ +Q E++RE++KT +++
Sbjct: 322 VENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQG--- 378
Query: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
ER+R++E+++R++EE +R++EE++Q+QE+++ +QEE++W++EE++Q+QEE+
Sbjct: 379 ---------ERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429
Query: 611 M-WEQEEKMWEQEEE-----DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
+ Q K+ +Q E + + +++ + E++++E +EK+ E+ + Q + E
Sbjct: 430 LALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLE 489
Query: 665 QE-------------EKMQGQEEK-------MREQEEKMQGQEEKMREQEEKMRGQEEKM 704
+ + + +EE+ + E E + M +EK G E+
Sbjct: 490 TQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQV- 548
Query: 705 WGQEEKMWGQEEKMWGQEEMREKEE--------------------RIRDQKEKMQERLPE 744
E + G + + MRE R+ ++E+M+ +L E
Sbjct: 549 ---ERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLLE 605
Query: 745 HEE-----------------RCSEPCLPPSK---------------VLCNMSHTGSVEPA 772
+E P P+ V +S +VEPA
Sbjct: 606 LQELVLPLVGNHEGHGKFLIAAQNPADEPTPGAPAPQELGAAGEQDVFYEVSLDNNVEPA 665
Query: 773 GGEAGEGSPQDNPTAQEIMQL 793
G A EGSP +NPT Q+I+QL
Sbjct: 666 PGVAREGSPHNNPTVQQIVQL 686
Score = 131 bits (330), Expect = 2e-30
Identities = 112/476 (23%), Positives = 226/476 (47%), Gaps = 68/476 (14%)
Query: 291 ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
E Q K +KKL+E +++ + ++K + + + Q +E
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQEL 74
Query: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
+ + + +E + +++ ++ E E+ +K E + E+ T+ +
Sbjct: 75 AVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEK 134
Query: 411 QEEKMQ----KQEENMWEQEEKE------WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
+ K K+ +E+E K+ + Q + E + L Q++E++ E
Sbjct: 135 ADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEEDRSSSCRE 194
Query: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE-K 519
+ ++++ + K R + Q + Q Q E+DE + K
Sbjct: 195 AVL--------QRRLQQTIKERALLNAHVTQVTESLKQVQL---------ERDEYAKHIK 237
Query: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
ER R Q++MW KM E +T ++EKK R+ R++E E+ + E + M E
Sbjct: 238 GERARWQERMW----KMSVEARTLKEEKK--------RDIHRIQELERSLSELKNQMAEP 285
Query: 580 E-----------EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
E++Q++ + +R++ E + E K+Q Q E Q + +E++ ++Q
Sbjct: 286 PSLAPPAVTSVVEQLQDEAKHLRQEVEGL---EGKLQSQVEN--NQALSLLSKEQKQRLQ 340
Query: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
EQEEM+ EQE + ++E++ EQ E++REQ++ ++EQ E+++ QE+++R+QEE++
Sbjct: 341 EQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERL----- 395
Query: 689 KMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
R++EE+++ QE+++W QEE++W +EE++ QE E Q K+ ++L E
Sbjct: 396 --RKEEERLQKQEKRLWDQEERLWKKEERLQKQE-----ERLALSQNHKLDKQLAE 444
Score = 85.1 bits (209), Expect = 2e-16
Identities = 88/363 (24%), Positives = 163/363 (44%), Gaps = 45/363 (12%)
Query: 125 ESKDLAGRLHHSWHFAGELQRALS---------------AVSTWHKKADRYIEELTKERD 169
E++ L H EL+R+LS AV++ ++ + L +E +
Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVE 312
Query: 170 ALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQT 229
L +L N+ L + E +K RL E E+ L +E +R E+ + +
Sbjct: 313 GLEGKLQSQVENNQALSLLSKE--QKQRLQEQEE---MLREQEAQRVREQERLCEQNERL 367
Query: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Q+ + Q E LR+QE+++RKQEE++ ++EERL++QE ++ +QEE++ ++E+RL++QE
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE 427
Query: 290 KELREQEKELREQKKLREQE---EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
+ L + + K+L E + E + +++ + E++++E +EK+ + Q Q
Sbjct: 428 ERLALSQNH-KLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQ 486
Query: 347 MREQE-------------QKMRDQEERMWEQDERLREK-EERMREQEKMWEQEEKMQEEE 392
E + Q + +EE + E E R M +EK E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546
Query: 393 RIREREKKMREEE---ETMREQEEKMQKQ----EENMWEQEEKEWQQQRLPEQKEKLWEQ 445
++ RE + + MRE + Q E E+ Q+ E K KL E
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLLEL 606
Query: 446 EKM 448
+++
Sbjct: 607 QEL 609
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 246 bits (629), Expect = 5e-65
Identities = 168/503 (33%), Positives = 282/503 (56%), Gaps = 82/503 (16%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP+LPPHPMM E++RQNKLA AKKK +Y+Q G+ A TKKKK ++ +PET
Sbjct: 1 MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAK-TKKKKTDS--SPET 57
Query: 61 TTSEGCHSPED------------------------------EKKASHQHQEALRREIEAQ 90
TTS G HSP D +K+ HQ +EA + E
Sbjct: 58 TTSGGGHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIH 117
Query: 91 D------HTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQ 144
TI ILT +K +L+T LY+++ AAR FE+ ESKDLAGRL +S EL+
Sbjct: 118 KAQMERLETINILTLEKADLKTTLYHTKRAARHFEE----ESKDLAGRLQYSLQRIQELE 173
Query: 145 RALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNA-ELQEKLRLAESEK 203
RAL AVST ++ DR + R+A+ + TI L + ++ E L+ + E+
Sbjct: 174 RALCAVSTQQQEEDRS----SSCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLER 229
Query: 204 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR---- 259
E ++K + + + + + V+ TL+EE R ++E E+ + + + +M +
Sbjct: 230 DEYAKHIKGERARWQERMWKM-SVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSL 288
Query: 260 --------------QEERLREQ----EGKMREQEEK-------MRRQEKRLREQEKELRE 294
+ + LR++ EGK++ Q E + Q++RL+EQE+ LRE
Sbjct: 289 APPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLRE 348
Query: 295 QE-KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
QE + +REQ++L EQ E+++EQ++ + EQ E++R+QE+++ +QEERL ++E+++++QE++
Sbjct: 349 QEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 354 MRDQEERMWEQDERLREKEER--MREQEKMWEQ-EEKMQEEERIREREKKMREEEETMRE 410
+ DQEER+W+++ERL+++EER + + K+ +Q E E + +K + E+ ++E
Sbjct: 409 LWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKE 468
Query: 411 QEEKMQKQEENMWEQEEKEWQQQ 433
+EK+ ++ Q+ ++ + Q
Sbjct: 469 LQEKLDEEHLEAASQQNQQLETQ 491
Score = 144 bits (363), Expect = 3e-34
Identities = 141/619 (22%), Positives = 285/619 (46%), Gaps = 114/619 (18%)
Query: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK-----MWEQEE 324
++ E E +++Q+K++ Q +E ++ E+ + + R + + E+ ++ +
Sbjct: 87 QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKR 146
Query: 325 KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER--LREKEERMREQEKMW 382
R EE+ RL ++++E E+ + + E+D RE R Q+ +
Sbjct: 147 AARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRLQQTIK 206
Query: 383 EQEEKMQEEERIREREKKMR-EEEETMREQEEKMQKQEENMWE--------QEEKEWQQQ 433
E+ ++ E K+++ E +E + + + + +E MW+ +EEK+
Sbjct: 207 ERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIH 266
Query: 434 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 493
R+ E + L E + + + + E E K RQE + E ++ Q E
Sbjct: 267 RIQELERSLSELKNQMAKPPSL--APPAVTSVVEQLQDEAKHLRQE-VEGLEGKLQSQVE 323
Query: 494 KMRDQEQKMWDQEERMWEQDERLREKE-ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
+ +Q++R+ EQ+E LRE+E +R+REQ+++ +Q E++RE++KT +++
Sbjct: 324 NNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQG----- 378
Query: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM- 611
ER+R++E+++R++EE +R++EE++Q+QE+++ +QEE++W++EE++Q+QEE++
Sbjct: 379 -------ERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLA 431
Query: 612 WEQEEKMWEQEEE-----DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Q K+ +Q E + + +++ + E++++E +EK+ E+ + Q+ + E +
Sbjct: 432 LSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQ 491
Query: 667 -------------EKMQGQEEK-------MREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
+ + +EE+ + E E + M +EK G E+
Sbjct: 492 LSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQV--- 548
Query: 707 QEEKMWGQEEKMWGQEEMREKEE--------------------RIRDQKEKMQERLPEHE 746
E + G + + MRE R+ ++E+M+ +L E +
Sbjct: 549 -ERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLLELQ 607
Query: 747 ERC-----------------------SEPCLPPSKVL---------CNMSHTGSVEPAGG 774
E P P + L +S +VEPA G
Sbjct: 608 ELVLPLVGNHEGHGKFLIAAQNPADEPTPGAPAPQELGAAGEQDDFYEVSLDNNVEPAPG 667
Query: 775 EAGEGSPQDNPTAQEIMQL 793
A EGSP DNPT Q+I+QL
Sbjct: 668 AAREGSPHDNPTVQQIVQL 686
Score = 131 bits (330), Expect = 2e-30
Identities = 109/476 (22%), Positives = 228/476 (47%), Gaps = 68/476 (14%)
Query: 291 ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
E Q K +KKL+E +++ + ++K + + + Q +E
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQEL 74
Query: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
+ + + +E + +++ ++ E E+ +K E + E+ T+ +
Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEK 134
Query: 411 QEEKMQ----KQEENMWEQEEKE------WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
+ K K+ +E+E K+ + QR+ E + L Q++E++ E
Sbjct: 135 ADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCRE 194
Query: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE-K 519
+ + ++ + + + Q+ E ++++ E+DE + K
Sbjct: 195 AVLHRR----LQQTIKERALLNAHVTQVTESLKQVQ-------------LERDEYAKHIK 237
Query: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
ER R Q++MW KM E +T ++EKK R+ R++E E+ + E + M +
Sbjct: 238 GERARWQERMW----KMSVEARTLKEEKK--------RDIHRIQELERSLSELKNQMAKP 285
Query: 580 E-----------EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
E++Q++ + +R++ E + E K+Q Q E Q + +E++ ++Q
Sbjct: 286 PSLAPPAVTSVVEQLQDEAKHLRQEVEGL---EGKLQSQVEN--NQALSLLSKEQKQRLQ 340
Query: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
EQEEM+ EQE + ++E++ EQ E++REQ++ ++EQ E+++ QE+++R+QEE++
Sbjct: 341 EQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERL----- 395
Query: 689 KMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
R++EE+++ QE+++W QEE++W +EE++ QE E Q K+ ++L E
Sbjct: 396 --RKEEERLQKQEKRLWDQEERLWKKEERLQKQE-----ERLALSQNHKLDKQLAE 444
Score = 86.7 bits (213), Expect = 8e-17
Identities = 92/365 (25%), Positives = 170/365 (46%), Gaps = 49/365 (13%)
Query: 125 ESKDLAGRLHHSWHFAGELQRALS---------------AVSTWHKKADRYIEELTKERD 169
E++ L H EL+R+LS AV++ ++ + L +E +
Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVE 312
Query: 170 ALSLELYRNTITNEELKKKNAELQEKLRLAES--EKSEIQLNVKELKRKLERAKFLLPQV 227
L +L N+ L + E +++L+ E + E+Q V+E +R E+ + L +
Sbjct: 313 GLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQ-RVREQERLCEQNERL--RE 369
Query: 228 QTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLRE 287
Q TLQE Q E LR+QE+++RKQEE++ ++EERL++QE ++ +QEE++ ++E+RL++
Sbjct: 370 QQKTLQE----QGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQK 425
Query: 288 QEKELREQEKELREQKKLREQE---EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
QE+ L + + K+L E + E + +++ + E++++E +EK+ + Q+
Sbjct: 426 QEERLALSQNH-KLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQ 484
Query: 345 KQMREQE-------------QKMRDQEERMWEQDERLREK-EERMREQEKMWEQEEKMQE 390
Q E + Q + +EE + E E R M +EK
Sbjct: 485 NQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADG 544
Query: 391 EERIREREKKMREEE---ETMREQEEKMQKQ----EENMWEQEEKEWQQQRLPEQKEKLW 443
E++ RE + + MRE + Q E E+ Q+ E K KL
Sbjct: 545 TEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLL 604
Query: 444 EQEKM 448
E +++
Sbjct: 605 ELQEL 609
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 237 bits (604), Expect = 4e-62
Identities = 170/463 (36%), Positives = 256/463 (55%), Gaps = 42/463 (9%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP LPPHP MSEKT+Q KLA AKKK Y W G A +KKKIN G++P+T
Sbjct: 1 MWPQPRLPPHPAMSEKTQQGKLAAAKKKLKAY--WQRKSPGIPAGANRKKKIN-GSSPDT 57
Query: 61 TTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED 120
TS G HSP D + E A T+ L Q EL AL S + +
Sbjct: 58 ATSGGYHSPGDSATGIYG-------EGRASSTTLEDLESQYQELAVALDSSSAIISQLTE 110
Query: 121 GNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTI 180
+ H H +L R+L K ++ E L E A ++ +
Sbjct: 111 NINSLVRTSKEEKKHEIHLVQKLGRSL------FKLKNQTAEPLAPEPPAGPSKVEQLQD 164
Query: 181 TNEELKKKNAELQEKLRLAESEKSEIQ--LNVKELKRKLERAKFLLPQVQTNTLQEE-MW 237
L+K+ + +L+ AE E +++ LN ++ +R E+ + L Q + QEE +
Sbjct: 165 ETNHLRKELESVGRQLQ-AEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLC 223
Query: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
QEE LREQE+++R+QEE++ QEERLRE E ++ EQEE++ QE+RLREQE+ L EQE+
Sbjct: 224 EQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEE 283
Query: 298 ELREQK-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK----------- 345
L EQ+ +LREQEE++ EQEE++ EQEE++ EQEE++ QEERL EQEK
Sbjct: 284 RLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEV 343
Query: 346 -------QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398
+ +E+++++ ++ ER+ E+ E L E+E ++ E++W Q+E +QE ER+RE E
Sbjct: 344 EKLLEQERRQEEQERLLER-ERLLEEVEELLEQERLRQQDERLW-QQETLQELERLRELE 401
Query: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQ-QQRLPEQKE 440
+ + E + EQ + + E + + + Q +Q++ E K+
Sbjct: 402 RMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKK 444
Score = 223 bits (569), Expect = 4e-58
Identities = 149/394 (37%), Positives = 239/394 (60%), Gaps = 47/394 (11%)
Query: 178 NTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKR--------------KLERAKFL 223
++ T E+L+ + EL L + + S++ N+ L R KL R+ F
Sbjct: 80 SSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFK 139
Query: 224 LPQVQTNTLQEEMWR---QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
L L E + E+L+++ +RK+ E + RQ + E + RR
Sbjct: 140 LKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN---RR 196
Query: 281 QEKRLREQEKELREQEKELREQK-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
QE+RLREQE+ LREQE+ LREQ+ +L EQEE+++EQEE++ EQEE++ EQEE++ EER
Sbjct: 197 QEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEER 256
Query: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
L EQE+++ EQE+++R+QEER+ EQ+ERL E+EER+REQ EER+ E+E+
Sbjct: 257 LCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQ------------EERLCEQEE 304
Query: 400 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 459
++RE+EE + EQEE++++QEE + EQ EK Q+RL E+ EKL EQE+ QE++E++ E+E
Sbjct: 305 RLREQEERLCEQEERLREQEERLCEQ-EKLPGQERLLEEVEKLLEQERRQEEQERLLERE 363
Query: 460 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE-----EKMRDQEQKMWDQEERMWEQDE 514
+ + EE + QE++R+Q++++W+QE E++R+ E+ + E ++EQ
Sbjct: 364 RLLEEVEE-------LLEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRA 416
Query: 515 RLREK-EERMREQKKMWQQEEKMREEKKTQEQEK 547
R EE E K Q E++++E KK+ E+
Sbjct: 417 EPRSGFEELNNENKSTLQLEQQVKELKKSGGAEE 450
Score = 206 bits (523), Expect = 9e-53
Identities = 134/427 (31%), Positives = 248/427 (58%), Gaps = 58/427 (13%)
Query: 197 RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256
R + + +++ +EL L+ + ++ Q+ N + R +E ++ E + +K
Sbjct: 78 RASSTTLEDLESQYQELAVALDSSSAIISQLTENI--NSLVRTSKEEKKHEIHL---VQK 132
Query: 257 MWRQEERLREQEGKMREQEEKMRRQE-KRLREQEKELREQEKELREQKKLREQEEQM--- 312
+ R +L+ Q + E + ++L+++ LR++ + + Q + + QM
Sbjct: 133 LGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSL 192
Query: 313 --QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 370
+ QEE++ EQEE++REQEE++ QEERL EQE+++REQE+++R+QEER+ EQ+ERLRE
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252
Query: 371 KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 430
EER+ EQE ER+ E+E+++RE+EE + EQEE++ +QEE + EQEE
Sbjct: 253 HEERLCEQE------------ERLCEQEERLREQEERLHEQEERLCEQEERLREQEE--- 297
Query: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
RL EQ+E+L +EQEE++ EQEE++R+QEE +++K+ QE++ E+ +++ E
Sbjct: 298 ---RLCEQEERL------REQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLE 348
Query: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
QE + +QE+ + + ERL E+ E + EQ+++ QQ+E++ W
Sbjct: 349 QERRQEEQERLL---------ERERLLEEVEELLEQERLRQQDERL-------------W 386
Query: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Q+E ++E ER+RE E+ + E + EQ + + E++ + + + E++++E ++
Sbjct: 387 -QQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKS 445
Query: 611 MWEQEEK 617
+E +
Sbjct: 446 GGAEEPR 452
Score = 196 bits (499), Expect = 6e-50
Identities = 124/387 (32%), Positives = 223/387 (57%), Gaps = 57/387 (14%)
Query: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
E++ E+ +K R KL+ Q + E + + + E R+E ++ Q
Sbjct: 122 EKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQ 181
Query: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
+ +M R Q+ERLRE+EER+REQ EER+RE+E+++ E+EE
Sbjct: 182 AEVENNQMLSLLNR--RQEERLREQEERLREQ------------EERLREQEERLCEQEE 227
Query: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
+REQEE++++QEE + EQEE RL E +E+L EQE E++ EQEE++R+QE
Sbjct: 228 RLREQEERLREQEERLCEQEE------RLREHEERLCEQE------ERLCEQEERLREQE 275
Query: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526
E ++ EQE+++ EQEE++R+QE+++ +QEER+ EQ+ERL E+EER+REQ
Sbjct: 276 E------------RLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQ 323
Query: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586
++ ++EK+ +++ E+ +K +QE + E+ER+ ERE+ + E EE++ +
Sbjct: 324 EERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELL---------E 374
Query: 587 EEKMREQEEKMWEQE-----EKMQEQEEKMWEQEEKMWEQEEE-----DKMQEQEEMMWE 636
+E++R+Q+E++W+QE E+++E E + E ++EQ E +++ + + +
Sbjct: 375 QERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQ 434
Query: 637 QEEKMQEQEEKMWEQEEKMREQEEKMR 663
E++++E ++ +E + E R
Sbjct: 435 LEQQVKELKKSGGAEEPRGSESAAAAR 461
Score = 194 bits (492), Expect = 4e-49
Identities = 123/345 (35%), Positives = 219/345 (63%), Gaps = 22/345 (6%)
Query: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
+R +E + + +QK ++++ + + + PE + E++Q++ + ++ E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQT-AEPLAPEPPAGPSKVEQLQDETNHLRKELE 174
Query: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520
+ Q + + +M R QE+++ EQEE++R+QE+++ +QEER+ EQ+ERLRE+E
Sbjct: 175 SVGRQLQAEVENNQMLSLLN-RRQEERLREQEERLREQEERLREQEERLCEQEERLREQE 233
Query: 521 ERMREQK-KMWQQEEKMRE-EKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMR 577
ER+REQ+ ++ +QEE++RE E++ EQE++ +QEE++RE EER+ E+E+++ E+EE +R
Sbjct: 234 ERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLR 293
Query: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ---EEEDKMQEQEEMM 634
EQEE++ EQEE++REQEE++ EQEE+++EQEE++ EQE+ ++ EE +K+ EQE
Sbjct: 294 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQ 353
Query: 635 WEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE-----EKMREQEEKMQGQEEK 689
EQE + + E++ E+ E++ EQ E++R+Q+E++ QE E++RE E ++ E
Sbjct: 354 EEQERLL--ERERLLEEVEELLEQ-ERLRQQDERLWQQETLQELERLRELERMLELGWEA 410
Query: 690 MREQEEKMR------GQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728
+ EQ + R E K Q E+ + +K G EE R E
Sbjct: 411 LYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSE 455
Score = 188 bits (477), Expect = 2e-47
Identities = 107/283 (37%), Positives = 190/283 (67%), Gaps = 33/283 (11%)
Query: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMW----EQDERLREKEERMREQKKMWQQEE 534
E+++++ + + ++ E + Q Q + + + Q+ERLRE+EER+REQ EE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQ------EE 213
Query: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
++RE+ +E +EER+RE+E+++RE+EE + EQEE+++E EE++ EQE
Sbjct: 214 RLREQ------------EERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQE 261
Query: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
E++ EQEE+++EQEE++ EQEE++ EQEE +++EQEE + EQEE+++EQEE++ EQEE+
Sbjct: 262 ERLCEQEERLREQEERLHEQEERLCEQEE--RLREQEERLCEQEERLREQEERLCEQEER 319
Query: 655 MREQEEKMREQEEKMQGQEEKMRE-----QEEKMQGQEEKMREQEEKMRGQEEKMWGQEE 709
+REQEE++ EQ EK+ GQE + E ++E+ Q ++E++ E+E + EE + ++E
Sbjct: 320 LREQEERLCEQ-EKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELL--EQE 376
Query: 710 KMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752
++ Q+E++W QE ++E ER+R+ + ++ E+ +EP
Sbjct: 377 RLRQQDERLWQQETLQEL-ERLRELERMLELGWEALYEQRAEP 418
Score = 184 bits (468), Expect = 2e-46
Identities = 120/319 (37%), Positives = 192/319 (60%), Gaps = 42/319 (13%)
Query: 505 QEERMWEQDERLREKEERMREQK-KMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-EERM 562
QEER+ EQ+ERLRE+EER+REQ+ ++ +QEE++RE QEE++RE EER+
Sbjct: 197 QEERLREQEERLREQEERLREQEERLCEQEERLRE-------------QEERLREQEERL 243
Query: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
E+E+++RE EE + EQEE++ EQEE++REQEE++ EQEE++ EQEE++ EQEE++ EQE
Sbjct: 244 CEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQE 303
Query: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQE-----EKMREQEEKMREQEEKMQGQEEKMR 677
E +++EQEE + EQEE+++EQEE++ EQE E++ E+ EK+ EQE + Q ++E++
Sbjct: 304 E--RLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERR-QEEQERLL 360
Query: 678 EQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKE-------ER 730
E+E ++ EE + ++E++R Q+E++W Q+E + E +RE E E
Sbjct: 361 ERERLLEEVEELL--EQERLRQQDERLW--------QQETLQELERLRELERMLELGWEA 410
Query: 731 IRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEI 790
+ +Q+ + + E +V G+ EP G E+ +
Sbjct: 411 LYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARPVAGAPVPQ 470
Query: 791 MQLFCGMK--NAQQCPGLG 807
CG Q+ PGLG
Sbjct: 471 GAWMCGQAGWTPQEHPGLG 489
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 215 bits (547), Expect = 2e-55
Identities = 169/707 (23%), Positives = 386/707 (54%), Gaps = 58/707 (8%)
Query: 78 QHQEALRREIE-AQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHS 136
+H+E + RE E AQ +L ++T++ + E GN+ K+++ +
Sbjct: 1338 RHKEVMPREEEQAQKKARDMLGLEETQV---ILKKGKKVIFLEPGNVTMGKEISKK-EEK 1393
Query: 137 WHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKL 196
F ++ AV +K + E+TKE +S E+ E++ K+ KL
Sbjct: 1394 KTFQKSPKQGRKAVQK-ERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEG----KL 1448
Query: 197 RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE-EMWRQEEELR--EQEKKIRKQ 253
+ E S ++ K+ + K QV T + + W++E E R ++E+K+ +
Sbjct: 1449 VMIERTPSW-----QDWKKAWDEWK----QVHGETRKSWKAWKEEWEKRLLQEEEKLHQA 1499
Query: 254 EEKMWRQEERLREQEGKMREQEEKM---------RRQEKRLREQEKELREQEKELREQKK 304
EK+ +EE L+E + K++ +E K ++++ E+E L E+ E+K+
Sbjct: 1500 GEKLSPEEEMLQEDK-KLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKE 1558
Query: 305 LREQEEQMQEQEEKMWEQ--------EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
+ EEQ QEE W + E+K ++E K+ ++EE+L ++E+Q+ ++E+K+
Sbjct: 1559 QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQ 1618
Query: 357 QEERMWEQDERLREKEERMREQEKMWEQ--EEKMQEEERIREREKKMREEEETMREQEEK 414
++ + D + + E + ++E+ Q E+ QE E++ ++ KK+ ++ E + +EEK
Sbjct: 1619 AYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEK 1678
Query: 415 MQKQEENMWEQEEKEWQQ-QRLPEQKEKL-W-EQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
+ K+ + E + Q+ + LP++++ L W E+E QE EE W+ EE +EE+ +
Sbjct: 1679 LAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQE 1738
Query: 472 EKKMWRQ-EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM-REQKKM 529
E K+ + +K+ E+E+ + Q EK+ ++E K+ +EE + ++ E+L + +E+M E++++
Sbjct: 1739 EGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERL 1798
Query: 530 WQQEEKMREEKKTQEQEKKTW-DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 588
++ E++ E+K Q+++ W + E++ + + + ++K + +E++ + +++EK+ +++E
Sbjct: 1799 GRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKE 1858
Query: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648
+ +E++ ++++ + + K+ + + + EE K+ +++E + +++EK+ E E+K+
Sbjct: 1859 NLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEE--KLTQEKETVIKKKEKLAETEKKL 1916
Query: 649 WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE----EKMRGQEEKM 704
+ E+ + +++EK+ +++ K+ E+ M + +++++G+ + +E++ E R EEKM
Sbjct: 1917 VQVEDSLAKKQEKLAQEKMKL-ALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKM 1975
Query: 705 ---WGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
G+E G+ + Q +M + E+ + ++K ++E++ HE+R
Sbjct: 1976 RLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDR 2022
Score = 204 bits (520), Expect = 2e-52
Identities = 187/758 (24%), Positives = 392/758 (51%), Gaps = 88/758 (11%)
Query: 71 DEKKASHQHQEALRREIEAQDHTIRILTCQKTELETA-LYYSQDAARKFE-DGNLGESKD 128
++K+A + + A E AQ+ R L ++ +L A + +QD + +G + ++
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQEE--RQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEE 1642
Query: 129 -LAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITN--EEL 185
LA R A +L + ++ +K R E+L K+ L+ +N + EEL
Sbjct: 1643 TLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAE--VKNILAQKVEEL 1700
Query: 186 --KKKNAELQEKLRLAESEKSEI---QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
+++N + QEK E E+ E +L+ KE + E K + + + +E + Q
Sbjct: 1701 PQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQR 1760
Query: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK--- 297
E+L E+E K+ ++EE + +++E+L + + KM E+EE++ R+ ++L E++ +L ++ +
Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWI 1820
Query: 298 ----ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
EL + K + Q++ + ++++ + +++EK+ +++E + +ERL +KQ+ + + K
Sbjct: 1821 NSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNK 1880
Query: 354 MRDQEERMWEQDERL-REKEERMREQEKMWEQEEKM-QEEERIREREKKMREE------E 405
+ + + + +E+L +EKE ++++EK+ E E+K+ Q E+ + ++++K+ +E E
Sbjct: 1881 LGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALE 1940
Query: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
+ M + +++++ + + E++ + +RL E+K +L E ++ + E ++ Q
Sbjct: 1941 KAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQ 2000
Query: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM-- 523
E E+K+ +EK+ ED++ EE + + + + +R++ Q +R K R
Sbjct: 2001 VEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLI 2060
Query: 524 ------------------------REQKKMWQQEEKM---------REEKKTQEQEK--- 547
R+++K+ Q+E KM +E + + EQ K
Sbjct: 2061 KKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDI 2120
Query: 548 KTWDQEEKMRE----EERMREREKKMREEEEMMREQEEKMQEQEEKM-REQEEKMWEQEE 602
K WD EK E E+++ +++K+ + M +EEKM E+E K+ R+ E + + EE
Sbjct: 2121 KEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEE 2180
Query: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
+ +EE++ ++ W + +E K ++ + + + E EE E+ E + ++ EK
Sbjct: 2181 EGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEK- 2239
Query: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ---EEKMWGQEEKMWGQEEKMW 719
+E + +EE+ RE+EE+ + EE++RE+EE+ + + EEK +EE+ +++K
Sbjct: 2240 ---QESLSSEEEEEREEEEERE--EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 720 GQEEMREKEERIRDQKEKMQER-------LPEHEERCS 750
+EE++EKEE +++E M E E EE CS
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCS 2332
Score = 192 bits (487), Expect = 1e-48
Identities = 130/520 (25%), Positives = 296/520 (56%), Gaps = 38/520 (7%)
Query: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
+E+ ++ +++ + +E M R+EE+ +++ M EE + L++ +K + +
Sbjct: 1325 REDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEET----QVILKKGKKVIFLEPGN 1380
Query: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
+ K++ ++EE+ Q+ +Q K ++E K+ + + + ++E+ M E+ ++M E
Sbjct: 1381 VTMGKEISKKEEKKTFQKSP--KQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLE 1438
Query: 359 ERMWEQDERLR--EKEERMREQEKMWEQEEKMQEEERI------REREKKMREEEETMRE 410
E++ +Q+ +L E+ ++ +K W++ +++ E R E EK++ +EEE + +
Sbjct: 1439 EKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQ 1498
Query: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW- 469
EK+ +EE + E ++ +W E+ +++WE + +E+ ++ EE++ +EE+
Sbjct: 1499 AGEKLSPEEEMLQEDKKLKW------EEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSR 1552
Query: 470 -GQEKKMWRQEKMRE-QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK 527
G+EK+ E+ R QE+ W + + R + +K QEER Q+E E+ +E++
Sbjct: 1553 EGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE-----EKLAQEER 1607
Query: 528 KMWQQEEKMREE--KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 585
++ Q+E K+ + K TQ+ + + + ++EE + +R +K+ +E E + ++ +K+ +
Sbjct: 1608 QLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAK 1667
Query: 586 QEEKMREQEEKMWEQEEKMQE------QEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
+ EK+ +EEK+ ++ K+ E Q+ + Q E+ + +E++ QE EE+ W+ EE
Sbjct: 1668 KWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEE 1727
Query: 640 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG 699
+ +EE++ ++E K+ E+++K+ E+EE + Q EK+ E+E K+ +EE + +++EK+
Sbjct: 1728 -LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQ 1786
Query: 700 QEEKMWGQEEKMWGQEEKMWGQE-EMREKEERIRDQKEKM 738
+EKM +EE++ + E++ ++ ++ +K ER + E++
Sbjct: 1787 HKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEEL 1826
Score = 192 bits (487), Expect = 1e-48
Identities = 160/707 (22%), Positives = 350/707 (49%), Gaps = 113/707 (15%)
Query: 142 ELQRALSAVSTW---HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRL 198
E QR + W H+K R ++ +E L+ E ++K A+ + +L
Sbjct: 1563 EEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE-----------EEKLAQEERQLAQ 1611
Query: 199 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ--EEMWRQEEELREQEKKIRKQEEK 256
E + ++ + + + R++ +A+ Q + Q E++ ++ E+L ++ KK+ K+ EK
Sbjct: 1612 EERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEK 1671
Query: 257 MWRQEERLREQEGKMREQE-------EKMRRQEKRLREQEKELREQEKEL---------- 299
+ R+EE+L ++ GK+ E + E++ ++E+ L QEKEL ++ +EL
Sbjct: 1672 VAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWK 1731
Query: 300 -----REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354
+E+ KL E+++++ E+EE + Q EK+ E+E K+ ++EE L ++++++ + ++KM
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 355 RDQEERMWEQDERLREKEERMREQEKMW-EQEEKMQEEERIREREKKMREEEETMREQEE 413
++EER+ + E+L EK+ ++ ++ + W E++ + + I ++K + +E++ + +++E
Sbjct: 1792 PEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851
Query: 414 KMQKQEENMWEQEEKEWQQQR---------------LPEQKEKLWEQ--------EKMQE 450
K+ +++EN+ +E+ ++ L + +EKL ++ EK+ E
Sbjct: 1852 KLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAE 1911
Query: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
E+K+ + E+ + ++E QEK EK Q + E + +E+ + + +R+
Sbjct: 1912 TEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLA 1971
Query: 511 EQDERLREKEERMRE--------QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
E+ RL E +E + + Q+KM Q E+++ E K + E++ + EE +
Sbjct: 1972 EEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEI 2031
Query: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ----------------EEKMQE 606
+ + + + + + + K+ + K+ ++ E + ++ +E+
Sbjct: 2032 AKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLT 2091
Query: 607 QEE-KMWEQEEKMWEQE-----EEDKM-------QEQEEMMWEQEEKMQEQEEKMWEQEE 653
QEE KM + + ++ +E E+ K+ E+ + + E+K+ ++ K+ +
Sbjct: 2092 QEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMR 2151
Query: 654 KMREQEEKMREQEEK---------MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
+M +EEKM E+E K + +EE E+EE + + + R+++E RG + K
Sbjct: 2152 RMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPK- 2210
Query: 705 WGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
EK Q +++ +E E+ E + D+ EK + E EE E
Sbjct: 2211 ----EKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253
Score = 186 bits (472), Expect = 8e-47
Identities = 170/579 (29%), Positives = 317/579 (54%), Gaps = 60/579 (10%)
Query: 155 KKADRYI---EELTKERDAL----SLELYRNTITNEELK---KKNAELQEKLRLAESEKS 204
+K +R+I EELTK + L +L + + E+ K +K L K RL S+K
Sbjct: 1814 QKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQ 1873
Query: 205 EIQLNVKELKRKLERAKFLLPQVQTNTLQEE--MWRQEEELREQEKKIRKQEEKMWRQEE 262
+Q+ K KL +L QV+ QE+ + +++E+L E EKK+ + E+ + +++E
Sbjct: 1874 LVQV-----KNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQE 1928
Query: 263 RLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR-EQKKLREQEEQMQEQEEKMWE 321
+L +++ K+ E+ M + +KRLR E ++ ++EK L E K+L E++ ++ E +E + +
Sbjct: 1929 KLAQEKMKLA-LEKAMVQGKKRLRG-ELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSK 1986
Query: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM--WEQDERLREKEERMREQE 379
E ++ KM + E+ L+E++ + E+K+ E+R+ E+ E + K E R Q
Sbjct: 1987 GETPETSRQRKMTQVEQELFERKLSL---EEKILLHEDRILAMEESEIAKGKLEFTRGQR 2043
Query: 380 KMWEQEEKMQEEER--IREREKKMREEEETMR--EQEEKMQKQEENMWEQEEKEWQQQRL 435
+ + K+ + R I++RE +E + + + +K+ + E + ++E K + +R
Sbjct: 2044 IFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRA 2103
Query: 436 PEQKEKLW--EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR-QEKMREQEDQMWEQE 492
KE+ EQ K+ +E W+ EK + E+ EKK+ R Q K+ + +M +E
Sbjct: 2104 LFVKERRLSIEQSKLDIKE---WDFSEK---RSELTKDEKKLARKQRKLANKMRRMINKE 2157
Query: 493 EKMRDQEQKMWDQEERMWEQDERLR--EKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
EKM ++E K+ + + DE E+EE + K+ W+ K +E K+ + ++K
Sbjct: 2158 EKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWR---KRKEAKRGDKPKEKFS 2214
Query: 551 DQEEKMREEERMREREKKMREE---EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607
Q +++ EE E + + +E +E + +EE+ +E+EE+ RE+EE E+EE+ +E+
Sbjct: 2215 SQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE-REEEEVREEEEERKEEE 2273
Query: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM----R 663
E EEK E+EEE+K ++++E +++E++QE+EE E+EE M E+E +
Sbjct: 2274 -----EGEEKQVEKEEEEKKKKKKE---KKKEEVQEKEEVFEEKEEIMSEEETESLSDEE 2325
Query: 664 EQEEKMQGQEEKMREQEEKMQGQEEKMREQEEK-MRGQE 701
E+EE +EE RE+E + ++ K++EQ K +RG+E
Sbjct: 2326 EEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364
Score = 131 bits (330), Expect = 2e-30
Identities = 102/447 (22%), Positives = 222/447 (49%), Gaps = 73/447 (16%)
Query: 308 QEEQMQEQEEKMWEQEEKM-REQEEKMWRQEERLWEQEKQM-REQEQKMRDQEERMWEQD 365
+E+ +Q +++ +E M RE+E+ + + L +E Q+ ++ +K+ E
Sbjct: 1325 REDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMG 1384
Query: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
+ + +KEE+ Q+ + + +Q+E ++ + +++M +EE M E+ E+M EE + +Q
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQ 1444
Query: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
E K +R P W+ K K W++ +++ G+ +K W+
Sbjct: 1445 EGKLVMIERTPS-----WQDWK------KAWDEWKQVH------GETRKSWKA------- 1480
Query: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
W++E W E+R+ +++E+L + E++ +++M Q+++K++ E+
Sbjct: 1481 ---WKEE----------W--EKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLK-----WEE 1520
Query: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE-QEEKMWEQEEKM 604
K+ W+ + +E+ + E+++ EEE+ RE EEK Q+ E+ R QEE W + +
Sbjct: 1521 WKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRK 1580
Query: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
+ + EK QEE+ K+ ++EEK+ ++E ++ ++E K+ +
Sbjct: 1581 RARAEKKRAQEER----------------------KLAQEEEKLAQEERQLAQEERKLAQ 1618
Query: 665 QEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEM 724
K+ + +M + E K +EE + ++ EK+ + EK+ + +K+ + EK+ +EE
Sbjct: 1619 AYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEK 1678
Query: 725 REKE----ERIRDQKEKMQERLPEHEE 747
K+ +++ + E LP+ E+
Sbjct: 1679 LAKKGGKLAEVKNILAQKVEELPQREQ 1705
Score = 116 bits (291), Expect = 7e-26
Identities = 113/554 (20%), Positives = 250/554 (45%), Gaps = 88/554 (15%)
Query: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR----E 328
E E ++ + + R Q + +K LR KK +E++ + E + E E E
Sbjct: 1071 ESEVAIKPSKGQRRGQAGVKKHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAPIE 1130
Query: 329 QEE----KMWRQEERLWEQEKQMREQEQKM-RDQEERMWEQDERLREKEERMREQEKMWE 383
EE W + + K + QE+ + +D ++ +++R+K ++ +K+ +
Sbjct: 1131 MEEASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKK 1190
Query: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQ-------------------EENMWE 424
+ +K + +E K+ EE T E+ + K+ + + W
Sbjct: 1191 KHKK-------KGKEAKVINEETTPPVMEQPVTKKVKIQGRGASGISGRRSTAGDGSSWR 1243
Query: 425 QEEKEWQQQRLPEQKEKLWEQ---------EKMQEQEEKIWE----------QEEKIRDQ 465
+ R+ + K+ E ++M WE +E K+ +
Sbjct: 1244 DDLCRLMALRISGSQTKMSENLNAELVTFAQEMLVDRHPSWELFQEICPLLKKESKVLLE 1303
Query: 466 EEMWG----QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521
+ W ++K ++ QE ++ +E +R +E ++E+ + + L +E
Sbjct: 1304 DLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEET 1363
Query: 522 RM---REQKKMWQQEEKMREEKK-TQEQEKKTWDQEEK-----MREEERMREREKKMREE 572
++ + +K ++ + + K+ ++++EKKT+ + K +++E ++ + +++M +E
Sbjct: 1364 QVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKE 1423
Query: 573 EEMMREQEEKMQEQEEKMREQE---------------EKMWEQEEKMQEQEEKMWEQEEK 617
E M E+ E+M EEK+ +QE +K W++ +++ + K W+ ++
Sbjct: 1424 ERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKE 1483
Query: 618 MWEQ---EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
WE+ +EE+K+ + E + +EE +QE ++ WE+ +++ E + +E++ + +EE
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543
Query: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
E+E +G+E++ + EE+ QEE W + + + EK QEE + +E ++
Sbjct: 1544 VTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE---EE 1600
Query: 735 KEKMQERLPEHEER 748
K +ER EER
Sbjct: 1601 KLAQEERQLAQEER 1614
Score = 110 bits (274), Expect = 7e-24
Identities = 104/450 (23%), Positives = 215/450 (47%), Gaps = 100/450 (22%)
Query: 49 KKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQD----HTIRILTCQKTEL 104
K+ ++ G PET+ ++K + QE R++ ++ H RIL +++E+
Sbjct: 1981 KETLSKGETPETSR---------QRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEI 2031
Query: 105 ETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEEL 164
R F G QR L+ S +L
Sbjct: 2032 AKGKLEFTRGQRIFVQG----------------------QRKLAKAS----------RKL 2059
Query: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESE----KSEIQLNVKELKRKLERA 220
K+R++LS E + N+ LK +++ +L + E K + L VKE + +E++
Sbjct: 2060 IKKRESLSKEPAK---LNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQS 2116
Query: 221 KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR-------- 272
K + + + + E+ + E++L +++K+ + +M +EE++ E+E K+
Sbjct: 2117 KLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVIL 2176
Query: 273 --------EQEE---------KMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQ-- 313
E+EE + R++ KR + +++ Q E+ ++ E+ E +
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 314 -EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 372
E++E + +EE+ RE+EE+ R+EE + E+E++ +E+E+ EE+ E++E ++K+
Sbjct: 2237 LEKQESLSSEEEEEREEEEE--REEEEVREEEEERKEEEEG----EEKQVEKEEEEKKKK 2290
Query: 373 ERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432
++ +++E++ E+EE +E+E I EE E++ ++EE +EE+ +EE + ++
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMS-----EEETESLSDEEE----EEESCSLEEEVDREK 2341
Query: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462
+ L ++K Q K+QEQ K E++
Sbjct: 2342 EILKKEK-----QFKLQEQRRKSLRGRERV 2366
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 212 bits (539), Expect = 1e-54
Identities = 158/466 (33%), Positives = 244/466 (52%), Gaps = 63/466 (13%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP LPPHP MSEKT+Q KLA AKKK Y W G A +KKK+ NG++P+T
Sbjct: 1 MWPQPRLPPHPAMSEKTQQGKLAAAKKKLKAY--WQRKSPGIPAGANRKKKV-NGSSPDT 57
Query: 61 TTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED 120
TS G HSP D + E A T++ L Q EL AL S + +
Sbjct: 58 ATSGGYHSPGDS-------ATGIYGEGRASSTTLQDLESQYQELAVALDSSSAIISQLTE 110
Query: 121 GNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTI 180
+ H H +L R+L
Sbjct: 111 NINSLVRTSKEEKKHEIHLVQKLGRSLF-------------------------------- 138
Query: 181 TNEELKKKNAE-LQEKLRLAESEKSEIQLNVKELKRKLER-AKFLLPQVQTNTLQEEM-W 237
+LK + AE L + S+ ++Q L+++LE + L +V+ N + +
Sbjct: 139 ---KLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR 195
Query: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
RQEE LREQE+++ +QEE++ QEERL EQE ++ EQEE++R QE+RLREQE+ L EQE
Sbjct: 196 RQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQE- 254
Query: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 357
++L EQEE++ EQEE++ EQE+ +E++ + E+L EQE++ EQE+ + +
Sbjct: 255 -----ERLCEQEERLCEQEERLCEQEK--LPGQERLLEEVEKLLEQERRQEEQERLL--E 305
Query: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417
ER+ ++ E L E+E ++ E++W Q+E ++E ER+RE E+ E E +RE E ++
Sbjct: 306 RERLLDEVEELLEQERLRQQDERLW-QQETLRELERLRELER--LRELERLRELERMLEL 362
Query: 418 QEENMWEQ--EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
E ++EQ E + ++ E K L +++++E E+ +E +
Sbjct: 363 GWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 408
Score = 159 bits (401), Expect = 1e-38
Identities = 115/372 (30%), Positives = 211/372 (56%), Gaps = 47/372 (12%)
Query: 178 NTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 237
++ T ++L+ + EL L + + S++ N+ L R + K L +++
Sbjct: 80 SSTTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEK-----KHEIHLVQKLG 134
Query: 238 RQEEELREQEKKIRKQEEKMWRQE-ERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296
R +L+ Q + E + E+L+++ +R++ E + RQ + E + L
Sbjct: 135 RSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN 194
Query: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
+ R++++LREQEE++ EQEE++ EQEE++ EQEE++ QEERL EQE+++REQE+++ +
Sbjct: 195 R--RQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHE 252
Query: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416
QEER+ EQ+ERL E+EER+ EQEK+ QE ++E E++ E+E++ +EE+E + E+E
Sbjct: 253 QEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERR-QEEQERLLERE---- 307
Query: 417 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476
RL ++ E+L EQE++++Q+E++W Q+E +R+ E ++
Sbjct: 308 -----------------RLLDEVEELLEQERLRQQDERLW-QQETLRELE-------RLR 342
Query: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK-EERMREQKKMWQQEEK 535
E++RE E++R+ E+ + E ++EQ R EE E K Q E++
Sbjct: 343 ELERLREL--------ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQ 394
Query: 536 MREEKKTQEQEK 547
++E +K+ E+
Sbjct: 395 VKELEKSGGAEE 406
Score = 142 bits (357), Expect = 2e-33
Identities = 81/272 (29%), Positives = 165/272 (60%), Gaps = 28/272 (10%)
Query: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
E ++++ ++K+ E++ Q + E + ++ + ++E+++EQEE++ EQEE++ +Q
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR-QEERLREQEERLHEQEERLHEQ 218
Query: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE 525
EE ++ EQE+++ EQEE++R+QE+++ +QEER+ EQ+ERL E+EER+ E
Sbjct: 219 EE------------RLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCE 266
Query: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 585
Q++ ++EK+ +++ E+ +K +QE + E+ER+ ERE+ + E EE++
Sbjct: 267 QEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELL--------- 317
Query: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645
++E++R+Q+E++W+QE +E + + E++ E E +++ E+ WE + + +
Sbjct: 318 EQERLRQQDERLWQQETL---RELERLRELERLRELERLRELERMLELGWEALYEQRAEP 374
Query: 646 EKMWEQ---EEKMREQEEKMREQEEKMQGQEE 674
+E+ E K Q E+ ++ EK G EE
Sbjct: 375 RSGFEELNNENKSTLQLEQQVKELEKSGGAEE 406
Score = 139 bits (350), Expect = 1e-32
Identities = 95/285 (33%), Positives = 169/285 (59%), Gaps = 41/285 (14%)
Query: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERL----REKEERMREQEKMWEQEEKMQEEER 393
E+L ++ +R++ + + Q + E ++ L R +EER+REQE ER
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQE------------ER 207
Query: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ-EKMQEQE 452
+ E+E+++ E+EE + EQEE++ +QEE + EQEE RL EQ+E+L EQ E++ EQE
Sbjct: 208 LHEQEERLHEQEERLCEQEERLCEQEERLREQEE------RLREQEERLHEQEERLCEQE 261
Query: 453 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQ 512
E++ EQEE++ +QE++ GQE+ + EK+ EQE + EQE + + +++ D+ E + EQ
Sbjct: 262 ERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL--ERERLLDEVEELLEQ 319
Query: 513 DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
ERLR+++ER +WQQ E +RE ++ +E E++RE ER+RE E+ +
Sbjct: 320 -ERLRQQDER------LWQQ-ETLRELERLREL--------ERLRELERLRELERMLELG 363
Query: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
E + EQ + + E++ + + + E++++E E+ +E +
Sbjct: 364 WEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 408
Score = 134 bits (336), Expect = 5e-31
Identities = 89/264 (33%), Positives = 159/264 (60%), Gaps = 43/264 (16%)
Query: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMW----EQDERLREKEERMREQKKMWQQEE 534
E+++++ + + ++ E + Q Q + + + Q+ERLRE+EER+ EQ
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQ-------- 211
Query: 535 KMREEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
E++ EQE++ +QEE++ E EER+RE+E+++RE+EE + EQEE++ EQEE++ EQ
Sbjct: 212 ----EERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQ 267
Query: 594 EEKMWEQE-----EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE-----QEEKMQE 643
EE++ EQE E++ E+ EK+ EQE + QEE++++ E+E ++ E ++E++++
Sbjct: 268 EERLCEQEKLPGQERLLEEVEKLLEQERR---QEEQERLLERERLLDEVEELLEQERLRQ 324
Query: 644 QEEKMWEQE-----EKMREQE-----EKMREQEEKMQ-GQEEKMREQEEKMQGQEEKMRE 692
Q+E++W+QE E++RE E E++RE E ++ G E ++ E G EE E
Sbjct: 325 QDERLWQQETLRELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNE 384
Query: 693 QEEKMRGQEEKMWGQEEKMWGQEE 716
+ + Q E+ + EK G EE
Sbjct: 385 NKSTL--QLEQQVKELEKSGGAEE 406
Score = 133 bits (335), Expect = 6e-31
Identities = 98/298 (32%), Positives = 177/298 (59%), Gaps = 34/298 (11%)
Query: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-EERMRER 565
E++ ++ LR++ E + Q + + +M + QE++ +QEE++ E EER+ E+
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLS-LLNRRQEERLREQEERLHEQEERLHEQ 218
Query: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
E+++ E+EE + EQEE+++EQEE++REQEE++ EQEE++ EQEE++ EQEE++ EQE
Sbjct: 219 EERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQE--- 275
Query: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
K+ QE ++ E+ EK+ EQE + E++E++ E+E + E EE + ++E++R+Q+E++
Sbjct: 276 KLPGQERLL-EEVEKLLEQERRQ-EEQERLLERERLLDEVEELL--EQERLRQQDERLWQ 331
Query: 686 QE-----EKMREQE-----EKMRGQEEKMWGQEEKMWGQE-EKMWGQEEMREKEE---RI 731
QE E++RE E E++R E + E ++ Q E G EE+ + + ++
Sbjct: 332 QETLRELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQL 391
Query: 732 RDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAG----GEAGEGSPQDNP 785
Q +++++ E R SE V G+ P G G+AG +PQ++P
Sbjct: 392 EQQVKELEKSGGAEEPRGSESAAAARPV------PGAPVPQGAWMCGQAG-WTPQEHP 442
Score = 129 bits (325), Expect = 9e-30
Identities = 84/243 (34%), Positives = 142/243 (58%), Gaps = 25/243 (10%)
Query: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
+R +E + + + Q+ + + K Q E + + E++++ +R+E E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELES 175
Query: 576 MREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
+ Q + E QEE++REQEE++ EQEE++ EQEE++ EQEE++ EQEE
Sbjct: 176 VGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEE- 234
Query: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
+++EQEE + EQEE++ EQEE++ EQEE++ EQEE++ EQE K+ GQE + E E
Sbjct: 235 -RLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQE-KLPGQERLLEEVE---- 288
Query: 685 GQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ-ERLP 743
K+ EQE + QE + + E++ + E++ QE +R+++ER+ Q+ + ERL
Sbjct: 289 ----KLLEQERRQEEQERLL--ERERLLDEVEELLEQERLRQQDERLWQQETLRELERLR 342
Query: 744 EHE 746
E E
Sbjct: 343 ELE 345
Score = 62.8 bits (151), Expect = 1e-09
Identities = 35/102 (34%), Positives = 64/102 (62%), Gaps = 4/102 (3%)
Query: 654 KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWG 713
K+ + +++ ++++ +++ + E Q R QEE++R QEE++ QEE++
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHE 217
Query: 714 QEEKMWGQEE-MREKEERIRDQKEKM---QERLPEHEERCSE 751
QEE++ QEE + E+EER+R+Q+E++ +ERL E EER E
Sbjct: 218 QEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCE 259
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 179 bits (455), Expect = 7e-45
Identities = 138/413 (33%), Positives = 208/413 (50%), Gaps = 62/413 (15%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP LPPHP MSEKT+Q KLA AKKK Y W G A +KKK+ NG++P+T
Sbjct: 1 MWPQPRLPPHPAMSEKTQQGKLAAAKKKLKAY--WQRKSPGIPAGANRKKKV-NGSSPDT 57
Query: 61 TTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED 120
TS G HSP D + E A T++ L Q EL AL S + +
Sbjct: 58 ATSGGYHSPGDS-------ATGIYGEGRASSTTLQDLESQYQELAVALDSSSAIISQLTE 110
Query: 121 GNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTI 180
+ H H +L R+L
Sbjct: 111 NINSLVRTSKEEKKHEIHLVQKLGRSLF-------------------------------- 138
Query: 181 TNEELKKKNAE-LQEKLRLAESEKSEIQLNVKELKRKLER-AKFLLPQVQTNTLQEEM-W 237
+LK + AE L + S+ ++Q L+++LE + L +V+ N + +
Sbjct: 139 ---KLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR 195
Query: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK-----RLREQEKEL 292
RQEE LREQE+++R+QEE++ QEERL EQE ++REQEE++ QEK RL E+ ++L
Sbjct: 196 RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKL 255
Query: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
+QE+ EQ++L E+E + E EE + ++E++R+Q+E++W Q+E L E E+ +RE E+
Sbjct: 256 LKQERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLW-QQETLRELER-LRELER 311
Query: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE 405
+ E ++EQ R E + + K +Q E++++E EK EE
Sbjct: 312 MLELGWEALYEQRAEPRSGFEELNNENK-----STLQLEQQVKELEKSGGAEE 359
Score = 112 bits (281), Expect = 1e-24
Identities = 83/316 (26%), Positives = 162/316 (51%), Gaps = 42/316 (13%)
Query: 197 RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256
R + + +++ +EL L+ + ++ Q+ T + + +EE + + ++K
Sbjct: 78 RASSTTLQDLESQYQELAVALDSSSAIISQL-TENINSLVRTSKEEKKHEIHLVQKLGRS 136
Query: 257 MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQE 316
+++ + + E + Q + ++L+++ LR++ + + Q + + QM
Sbjct: 137 LFKLKNQTAEP---LAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLL 193
Query: 317 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
+ RQEERL EQE+++REQE+++ +QEER+ EQ+ERLRE+EER+
Sbjct: 194 NR----------------RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLC 237
Query: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
EQEK+ QE ++E E++ ++E++ +EE+E + E+E + + EE + +Q+RL
Sbjct: 238 EQEKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELL--------EQERLR 288
Query: 437 EQKEKLWEQEKMQEQE-------------EKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
+Q E+LW+QE ++E E E ++EQ + R E E K Q + +
Sbjct: 289 QQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQV 348
Query: 484 QEDQMWEQEEKMRDQE 499
+E + E+ R E
Sbjct: 349 KELEKSGGAEEPRGSE 364
Score = 111 bits (277), Expect = 3e-24
Identities = 72/273 (26%), Positives = 152/273 (55%), Gaps = 28/273 (10%)
Query: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
+R +E + + +QK ++++ + + + P+ + E++Q++ + ++ E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQT-AEPLAPQPPAGPSKVEQLQDETNHLRKELE 174
Query: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520
+ Q + + +M R QE+++ EQEE++R+QE+++ +QEER+ EQ+ERLRE+E
Sbjct: 175 SVGRQLQAEVENNQMLSLLN-RRQEERLREQEERLREQEERLCEQEERLCEQEERLREQE 233
Query: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
ER+ EQ+K+ QE + E +K +QE+ + E+ER+ ERE+ + E EE++
Sbjct: 234 ERLCEQEKLPGQERLLEEVEKLLKQER-------RQEEQERLLERERLLDEVEELL---- 282
Query: 581 EKMQEQEEKMREQEEKMWEQE-----EKMQEQEEKMWEQEEKMWEQEEE-----DKMQEQ 630
++E++R+Q+E++W+QE E+++E E + E ++EQ E +++ +
Sbjct: 283 -----EQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNE 337
Query: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
+ + E++++E E+ +E + E R
Sbjct: 338 NKSTLQLEQQVKELEKSGGAEEPRGSESAAAAR 370
Score = 110 bits (275), Expect = 5e-24
Identities = 72/241 (29%), Positives = 143/241 (59%), Gaps = 16/241 (6%)
Query: 322 QEEKMREQE--EKMWRQEERLWEQEKQ-MREQEQKMRDQEERMWEQDERLREKEERMREQ 378
+EEK E +K+ R +L Q + + Q + E++ ++ LR++ E + Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 379 EKMWEQEEKM------QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432
+ + +M ++EER+RE+E+++RE+EE + EQEE++ +QEE + EQEE+ +Q
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQ 239
Query: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
++LP Q+ L E EK+ +QE + E++E++ ++E + + +++ QE++R+Q++++W+QE
Sbjct: 240 EKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELLEQERLRQQDERLWQQE 298
Query: 493 -----EKMRDQEQKMWDQEERMWEQDERLREK-EERMREQKKMWQQEEKMREEKKTQEQE 546
E++R+ E+ + E ++EQ R EE E K Q E++++E +K+ E
Sbjct: 299 TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAE 358
Query: 547 K 547
+
Sbjct: 359 E 359
Score = 100 bits (249), Expect = 6e-21
Identities = 63/174 (36%), Positives = 107/174 (61%), Gaps = 19/174 (10%)
Query: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE-----EKMWEQEE- 623
R +EE +REQEE+++EQEE++ EQEE++ EQEE+++EQEE++ EQE E++ E+ E
Sbjct: 195 RRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEK 254
Query: 624 ---EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
+++ QE++E + E+E + E EE + ++E++R+Q+E++ +QE + E++RE E
Sbjct: 255 LLKQERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLR--ELERLRELE 310
Query: 681 EKMQGQEEKMREQEEKMR------GQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728
++ E + EQ + R E K Q E+ + EK G EE R E
Sbjct: 311 RMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSE 364
Score = 99.8 bits (247), Expect = 9e-21
Identities = 65/172 (37%), Positives = 110/172 (63%), Gaps = 16/172 (9%)
Query: 552 QEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-----EKMWEQEEKMQ 605
QEE++RE EER+RE+E+++ E+EE + EQEE+++EQEE++ EQE E++ E+ EK+
Sbjct: 197 QEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLL 256
Query: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
+QE + EQE + E E + E EE++ ++E++++Q+E++W Q+E +RE E++RE
Sbjct: 257 KQERRQEEQERLL---ERERLLDEVEELL--EQERLRQQDERLW-QQETLREL-ERLREL 309
Query: 666 EEKMQ-GQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716
E ++ G E ++ E G EE E + + Q E+ + EK G EE
Sbjct: 310 ERMLELGWEALYEQRAEPRSGFEELNNENKSTL--QLEQQVKELEKSGGAEE 359
Score = 97.1 bits (240), Expect = 6e-20
Identities = 68/213 (31%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Query: 366 ERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 424
E+L+++ +R++ E + Q + E ++ R +EE +REQEE++++QEE + E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN--RRQEERLREQEERLREQEERLCE 217
Query: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
QEE RL EQ+E+L EQE+ ++EK+ QE + + E++ QE++ QE++ E+
Sbjct: 218 QEE------RLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLER 271
Query: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM----WQQEEKMREEK 540
E + E EE + +++++ Q+ER+W+Q E LRE ER+RE ++M W+ + R E
Sbjct: 272 ERLLDEVEELL--EQERLRQQDERLWQQ-ETLREL-ERLRELERMLELGWEALYEQRAEP 327
Query: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
++ +E + + ++ E++++E EK EE
Sbjct: 328 RSGFEELNN-ENKSTLQLEQQVKELEKSGGAEE 359
Score = 95.5 bits (236), Expect = 2e-19
Identities = 81/292 (27%), Positives = 151/292 (51%), Gaps = 34/292 (11%)
Query: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
+R +E + + + Q+ + + K Q E + E++++ +R+E E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELES 175
Query: 576 MREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE-- 622
+ Q + E QEE++REQEE++ EQEE++ EQEE++ EQEE++ EQE
Sbjct: 176 VGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEER 235
Query: 623 --EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
E++K+ QE ++ E+ EK+ +QE + E++E++ E+E + E EE + ++E++R+Q+
Sbjct: 236 LCEQEKLPGQERLL-EEVEKLLKQERRQ-EEQERLLERERLLDEVEELL--EQERLRQQD 291
Query: 681 EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE---RIRDQKEK 737
E++ Q+E +RE E + G E + E G EE+ + + ++ Q ++
Sbjct: 292 ERL-WQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350
Query: 738 MQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAG----GEAGEGSPQDNP 785
+++ E R SE V G+ P G G+AG +PQ++P
Sbjct: 351 LEKSGGAEEPRGSESAAAARPV------PGAPVPQGAWMCGQAG-WTPQEHP 395
Score = 95.1 bits (235), Expect = 2e-19
Identities = 71/238 (29%), Positives = 129/238 (54%), Gaps = 42/238 (17%)
Query: 386 EKMQEEERIRERE-----KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
E++Q+E +E ++++ E E + ++QEE + EQEE RL EQ+E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEE------RLREQEE 213
Query: 441 KLWEQ-EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
+L EQ E++ EQEE++ EQEE++ +QE++ GQE+ + EK+ +QE + EQE + +
Sbjct: 214 RLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLL--ER 271
Query: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
+++ D+ E + EQ ERLR+++ER +WQQ E +RE
Sbjct: 272 ERLLDEVEELLEQ-ERLRQQDER------LWQQ---------------------ETLREL 303
Query: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
ER+RE E+ + E + EQ + + E++ + + + E++++E E+ +E +
Sbjct: 304 ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 361
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 179 bits (455), Expect = 7e-45
Identities = 138/413 (33%), Positives = 208/413 (50%), Gaps = 62/413 (15%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP LPPHP MSEKT+Q KLA AKKK Y W G A +KKK+ NG++P+T
Sbjct: 1 MWPQPRLPPHPAMSEKTQQGKLAAAKKKLKAY--WQRKSPGIPAGANRKKKV-NGSSPDT 57
Query: 61 TTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED 120
TS G HSP D + E A T++ L Q EL AL S + +
Sbjct: 58 ATSGGYHSPGDS-------ATGIYGEGRASSTTLQDLESQYQELAVALDSSSAIISQLTE 110
Query: 121 GNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTI 180
+ H H +L R+L
Sbjct: 111 NINSLVRTSKEEKKHEIHLVQKLGRSLF-------------------------------- 138
Query: 181 TNEELKKKNAE-LQEKLRLAESEKSEIQLNVKELKRKLER-AKFLLPQVQTNTLQEEM-W 237
+LK + AE L + S+ ++Q L+++LE + L +V+ N + +
Sbjct: 139 ---KLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR 195
Query: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK-----RLREQEKEL 292
RQEE LREQE+++R+QEE++ QEERL EQE ++REQEE++ QEK RL E+ ++L
Sbjct: 196 RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKL 255
Query: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
+QE+ EQ++L E+E + E EE + ++E++R+Q+E++W Q+E L E E+ +RE E+
Sbjct: 256 LKQERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLW-QQETLRELER-LRELER 311
Query: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE 405
+ E ++EQ R E + + K +Q E++++E EK EE
Sbjct: 312 MLELGWEALYEQRAEPRSGFEELNNENK-----STLQLEQQVKELEKSGGAEE 359
Score = 112 bits (281), Expect = 1e-24
Identities = 83/316 (26%), Positives = 162/316 (51%), Gaps = 42/316 (13%)
Query: 197 RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256
R + + +++ +EL L+ + ++ Q+ T + + +EE + + ++K
Sbjct: 78 RASSTTLQDLESQYQELAVALDSSSAIISQL-TENINSLVRTSKEEKKHEIHLVQKLGRS 136
Query: 257 MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQE 316
+++ + + E + Q + ++L+++ LR++ + + Q + + QM
Sbjct: 137 LFKLKNQTAEP---LAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLL 193
Query: 317 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
+ RQEERL EQE+++REQE+++ +QEER+ EQ+ERLRE+EER+
Sbjct: 194 NR----------------RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLC 237
Query: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
EQEK+ QE ++E E++ ++E++ +EE+E + E+E + + EE + +Q+RL
Sbjct: 238 EQEKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELL--------EQERLR 288
Query: 437 EQKEKLWEQEKMQEQE-------------EKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
+Q E+LW+QE ++E E E ++EQ + R E E K Q + +
Sbjct: 289 QQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQV 348
Query: 484 QEDQMWEQEEKMRDQE 499
+E + E+ R E
Sbjct: 349 KELEKSGGAEEPRGSE 364
Score = 111 bits (277), Expect = 3e-24
Identities = 72/273 (26%), Positives = 152/273 (55%), Gaps = 28/273 (10%)
Query: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
+R +E + + +QK ++++ + + + P+ + E++Q++ + ++ E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQT-AEPLAPQPPAGPSKVEQLQDETNHLRKELE 174
Query: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520
+ Q + + +M R QE+++ EQEE++R+QE+++ +QEER+ EQ+ERLRE+E
Sbjct: 175 SVGRQLQAEVENNQMLSLLN-RRQEERLREQEERLREQEERLCEQEERLCEQEERLREQE 233
Query: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
ER+ EQ+K+ QE + E +K +QE+ + E+ER+ ERE+ + E EE++
Sbjct: 234 ERLCEQEKLPGQERLLEEVEKLLKQER-------RQEEQERLLERERLLDEVEELL---- 282
Query: 581 EKMQEQEEKMREQEEKMWEQE-----EKMQEQEEKMWEQEEKMWEQEEE-----DKMQEQ 630
++E++R+Q+E++W+QE E+++E E + E ++EQ E +++ +
Sbjct: 283 -----EQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNE 337
Query: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
+ + E++++E E+ +E + E R
Sbjct: 338 NKSTLQLEQQVKELEKSGGAEEPRGSESAAAAR 370
Score = 110 bits (275), Expect = 5e-24
Identities = 72/241 (29%), Positives = 143/241 (59%), Gaps = 16/241 (6%)
Query: 322 QEEKMREQE--EKMWRQEERLWEQEKQ-MREQEQKMRDQEERMWEQDERLREKEERMREQ 378
+EEK E +K+ R +L Q + + Q + E++ ++ LR++ E + Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 379 EKMWEQEEKM------QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432
+ + +M ++EER+RE+E+++RE+EE + EQEE++ +QEE + EQEE+ +Q
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQ 239
Query: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
++LP Q+ L E EK+ +QE + E++E++ ++E + + +++ QE++R+Q++++W+QE
Sbjct: 240 EKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELLEQERLRQQDERLWQQE 298
Query: 493 -----EKMRDQEQKMWDQEERMWEQDERLREK-EERMREQKKMWQQEEKMREEKKTQEQE 546
E++R+ E+ + E ++EQ R EE E K Q E++++E +K+ E
Sbjct: 299 TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAE 358
Query: 547 K 547
+
Sbjct: 359 E 359
Score = 100 bits (249), Expect = 6e-21
Identities = 63/174 (36%), Positives = 107/174 (61%), Gaps = 19/174 (10%)
Query: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE-----EKMWEQEE- 623
R +EE +REQEE+++EQEE++ EQEE++ EQEE+++EQEE++ EQE E++ E+ E
Sbjct: 195 RRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEK 254
Query: 624 ---EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
+++ QE++E + E+E + E EE + ++E++R+Q+E++ +QE + E++RE E
Sbjct: 255 LLKQERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLR--ELERLRELE 310
Query: 681 EKMQGQEEKMREQEEKMR------GQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728
++ E + EQ + R E K Q E+ + EK G EE R E
Sbjct: 311 RMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSE 364
Score = 99.8 bits (247), Expect = 9e-21
Identities = 65/172 (37%), Positives = 110/172 (63%), Gaps = 16/172 (9%)
Query: 552 QEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-----EKMWEQEEKMQ 605
QEE++RE EER+RE+E+++ E+EE + EQEE+++EQEE++ EQE E++ E+ EK+
Sbjct: 197 QEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLL 256
Query: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
+QE + EQE + E E + E EE++ ++E++++Q+E++W Q+E +RE E++RE
Sbjct: 257 KQERRQEEQERLL---ERERLLDEVEELL--EQERLRQQDERLW-QQETLREL-ERLREL 309
Query: 666 EEKMQ-GQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716
E ++ G E ++ E G EE E + + Q E+ + EK G EE
Sbjct: 310 ERMLELGWEALYEQRAEPRSGFEELNNENKSTL--QLEQQVKELEKSGGAEE 359
Score = 97.1 bits (240), Expect = 6e-20
Identities = 68/213 (31%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Query: 366 ERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 424
E+L+++ +R++ E + Q + E ++ R +EE +REQEE++++QEE + E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN--RRQEERLREQEERLREQEERLCE 217
Query: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
QEE RL EQ+E+L EQE+ ++EK+ QE + + E++ QE++ QE++ E+
Sbjct: 218 QEE------RLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLER 271
Query: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM----WQQEEKMREEK 540
E + E EE + +++++ Q+ER+W+Q E LRE ER+RE ++M W+ + R E
Sbjct: 272 ERLLDEVEELL--EQERLRQQDERLWQQ-ETLREL-ERLRELERMLELGWEALYEQRAEP 327
Query: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
++ +E + + ++ E++++E EK EE
Sbjct: 328 RSGFEELNN-ENKSTLQLEQQVKELEKSGGAEE 359
Score = 95.5 bits (236), Expect = 2e-19
Identities = 81/292 (27%), Positives = 151/292 (51%), Gaps = 34/292 (11%)
Query: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
+R +E + + + Q+ + + K Q E + E++++ +R+E E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELES 175
Query: 576 MREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE-- 622
+ Q + E QEE++REQEE++ EQEE++ EQEE++ EQEE++ EQE
Sbjct: 176 VGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEER 235
Query: 623 --EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
E++K+ QE ++ E+ EK+ +QE + E++E++ E+E + E EE + ++E++R+Q+
Sbjct: 236 LCEQEKLPGQERLL-EEVEKLLKQERRQ-EEQERLLERERLLDEVEELL--EQERLRQQD 291
Query: 681 EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE---RIRDQKEK 737
E++ Q+E +RE E + G E + E G EE+ + + ++ Q ++
Sbjct: 292 ERL-WQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350
Query: 738 MQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAG----GEAGEGSPQDNP 785
+++ E R SE V G+ P G G+AG +PQ++P
Sbjct: 351 LEKSGGAEEPRGSESAAAARPV------PGAPVPQGAWMCGQAG-WTPQEHP 395
Score = 95.1 bits (235), Expect = 2e-19
Identities = 71/238 (29%), Positives = 129/238 (54%), Gaps = 42/238 (17%)
Query: 386 EKMQEEERIRERE-----KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
E++Q+E +E ++++ E E + ++QEE + EQEE RL EQ+E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEE------RLREQEE 213
Query: 441 KLWEQ-EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
+L EQ E++ EQEE++ EQEE++ +QE++ GQE+ + EK+ +QE + EQE + +
Sbjct: 214 RLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLL--ER 271
Query: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
+++ D+ E + EQ ERLR+++ER +WQQ E +RE
Sbjct: 272 ERLLDEVEELLEQ-ERLRQQDER------LWQQ---------------------ETLREL 303
Query: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
ER+RE E+ + E + EQ + + E++ + + + E++++E E+ +E +
Sbjct: 304 ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 361
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 178 bits (451), Expect = 2e-44
Identities = 138/413 (33%), Positives = 207/413 (50%), Gaps = 62/413 (15%)
Query: 1 MWPQPHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPET 60
MWPQP LPPHP MSEKT+Q KLA AKKK Y W G A +KKK+ NG++P+T
Sbjct: 1 MWPQPRLPPHPAMSEKTQQGKLAAAKKKLKAY--WQRKSPGIPAGANRKKKV-NGSSPDT 57
Query: 61 TTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED 120
TS G HSP D + E A T++ L Q EL AL S + +
Sbjct: 58 ATSGGYHSPGDS-------ATGIYGEGRASSTTLQDLESQYQELAVALDSSSAIISQLTE 110
Query: 121 GNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTI 180
+ H H +L R+L
Sbjct: 111 NINSLVRTSKEEKKHEIHLVQKLGRSLF-------------------------------- 138
Query: 181 TNEELKKKNAE-LQEKLRLAESEKSEIQLNVKELKRKLER-AKFLLPQVQTNTLQEEM-W 237
+LK + AE L + S+ ++Q L+++LE + L +V+ N + +
Sbjct: 139 ---KLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR 195
Query: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK-----RLREQEKEL 292
RQEE LREQE+++R+QEE++ QEERL EQE ++ EQEE++ QEK RL E+ ++L
Sbjct: 196 RQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKL 255
Query: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
EQE+ EQ++L E+E + E EE + ++E++R+Q+E++W Q+E L E E+ +RE E+
Sbjct: 256 LEQERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLW-QQETLRELER-LRELER 311
Query: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE 405
+ E ++EQ R E + + K +Q E++++E EK EE
Sbjct: 312 MLELGWEALYEQRAEPRSGFEELNNENK-----STLQLEQQVKELEKSGGAEE 359
Score = 114 bits (285), Expect = 4e-25
Identities = 85/261 (32%), Positives = 143/261 (54%), Gaps = 25/261 (9%)
Query: 200 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR---QEEELREQEKKIRKQEEK 256
E +K EI L +KL R+ F L L E + E+L+++ +RK+ E
Sbjct: 121 EEKKHEIHL-----VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELES 175
Query: 257 MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQE 316
+ RQ + E + RRQE+RLREQE+ LREQE+ +L EQEE++ EQE
Sbjct: 176 VGRQLQAEVENNQMLSLLN---RRQEERLREQEERLREQEE------RLHEQEERLCEQE 226
Query: 317 EKMWEQEEKMREQE-----EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371
E++ EQEE++ EQE E++ + E+L EQE++ EQE+ + + ER+ ++ E L E+
Sbjct: 227 ERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL--ERERLLDEVEELLEQ 284
Query: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 431
E ++ E++W+QE ++E ER+RE E+ + E + EQ + + E + + + Q
Sbjct: 285 ERLRQQDERLWQQET-LRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQ 343
Query: 432 QQRLPEQKEKLWEQEKMQEQE 452
++ ++ EK E+ + E
Sbjct: 344 LEQQVKELEKSGGAEEPRGSE 364
Score = 112 bits (281), Expect = 1e-24
Identities = 64/201 (31%), Positives = 127/201 (63%), Gaps = 13/201 (6%)
Query: 359 ERMWEQDERLREKEERMREQEKMWEQEEKM------QEEERIREREKKMREEEETMREQE 412
E++ ++ LR++ E + Q + + +M ++EER+RE+E+++RE+EE + EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQE 219
Query: 413 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 472
E++ +QEE + EQEE+ +Q++LP Q+ L E EK+ EQE + E++E++ ++E + +
Sbjct: 220 ERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERR-QEEQERLLERERLLDEV 278
Query: 473 KKMWRQEKMREQEDQMWEQE-----EKMRDQEQKMWDQEERMWEQDERLREK-EERMREQ 526
+++ QE++R+Q++++W+QE E++R+ E+ + E ++EQ R EE E
Sbjct: 279 EELLEQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNEN 338
Query: 527 KKMWQQEEKMREEKKTQEQEK 547
K Q E++++E +K+ E+
Sbjct: 339 KSTLQLEQQVKELEKSGGAEE 359
Score = 111 bits (277), Expect = 3e-24
Identities = 77/243 (31%), Positives = 134/243 (55%), Gaps = 28/243 (11%)
Query: 276 EKMRRQEKRLREQEKELREQEKELREQK--KLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
+K+ R +L+ Q E E K +L+++ ++++ E + Q + E + +
Sbjct: 131 QKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQML 190
Query: 334 W----RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQ 389
RQEERL EQE+++REQE+++ +QEER+ EQ+ERL E+EER+ EQEK+ QE ++
Sbjct: 191 SLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLE 250
Query: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
E E++ E+E++ +EE+E + E+E + + EE + +Q+RL +Q E+LW+QE ++
Sbjct: 251 EVEKLLEQERR-QEEQERLLERERLLDEVEELL--------EQERLRQQDERLWQQETLR 301
Query: 450 EQE-------------EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
E E E ++EQ + R E E K Q + + +E + E+ R
Sbjct: 302 ELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 361
Query: 497 DQE 499
E
Sbjct: 362 GSE 364
Score = 110 bits (276), Expect = 4e-24
Identities = 73/273 (26%), Positives = 151/273 (55%), Gaps = 28/273 (10%)
Query: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
+R +E + + +QK ++++ + + + PE + E++Q++ + ++ E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQT-AEPLAPEPPAGPSKVEQLQDETNHLRKELE 174
Query: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520
+ Q + + +M R QE+++ EQEE++R+QE+++ +QEER+ EQ+ERL E+E
Sbjct: 175 SVGRQLQAEVENNQMLSLLN-RRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQE 233
Query: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
ER+ EQ+K+ QE + E +K EQE+ + E+ER+ ERE+ + E EE++
Sbjct: 234 ERLCEQEKLPGQERLLEEVEKLLEQER-------RQEEQERLLERERLLDEVEELL---- 282
Query: 581 EKMQEQEEKMREQEEKMWEQE-----EKMQEQEEKMWEQEEKMWEQEEE-----DKMQEQ 630
++E++R+Q+E++W+QE E+++E E + E ++EQ E +++ +
Sbjct: 283 -----EQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNE 337
Query: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
+ + E++++E E+ +E + E R
Sbjct: 338 NKSTLQLEQQVKELEKSGGAEEPRGSESAAAAR 370
Score = 105 bits (261), Expect = 2e-22
Identities = 74/258 (28%), Positives = 145/258 (56%), Gaps = 29/258 (11%)
Query: 287 EQEKELREQEKELREQKKLREQEEQMQEQE--------EKMWEQEEKMREQEEKMWRQEE 338
E++ E+ +K R KL+ Q + E E++ ++ +R++ E + RQ +
Sbjct: 122 EKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQ 181
Query: 339 RLWEQEKQM----REQEQKMRDQEERMWEQDERLREKEERMREQ-EKMWEQEEKMQEEER 393
E + + R QE+++R+QEER+ EQ+ERL E+EER+ EQ E++ EQEE++ E+E+
Sbjct: 182 AEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEK 241
Query: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453
+ +E ++ EE E + EQE + ++QE + +++RL ++ E+L EQE++++Q+E
Sbjct: 242 LPGQE-RLLEEVEKLLEQERRQEEQERLL--------ERERLLDEVEELLEQERLRQQDE 292
Query: 454 KIWEQE-----EKIRDQEEM--WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
++W+QE E++R+ E M G E ++ + R +++ + + EQ++ + E
Sbjct: 293 RLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELE 352
Query: 507 ERMWEQDERLREKEERMR 524
+ ++ R E R
Sbjct: 353 KSGGAEEPRGSESAAAAR 370
Score = 102 bits (253), Expect = 2e-21
Identities = 70/211 (33%), Positives = 120/211 (56%), Gaps = 22/211 (10%)
Query: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
K E+++++ ++E + + E E R+EER+RE+E+++RE+EE + E
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHE 217
Query: 579 QEEKMQEQEEKMREQEEKMWEQE------------EKMQEQEEKMWEQEEKMWEQEEEDK 626
QEE++ EQEE++ EQEE++ EQE EK+ EQE + EQE + E E
Sbjct: 218 QEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL---ERERL 274
Query: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ-GQEEKMREQEEKMQG 685
+ E EE++ ++E++++Q+E++W Q+E +RE E++RE E ++ G E ++ E G
Sbjct: 275 LDEVEELL--EQERLRQQDERLW-QQETLREL-ERLRELERMLELGWEALYEQRAEPRSG 330
Query: 686 QEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716
EE E + + Q E+ + EK G EE
Sbjct: 331 FEELNNENKSTL--QLEQQVKELEKSGGAEE 359
Score = 101 bits (252), Expect = 2e-21
Identities = 65/173 (37%), Positives = 106/173 (61%), Gaps = 17/173 (9%)
Query: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ---EEEDK 626
R +EE +REQEE+++EQEE++ EQEE++ EQEE++ EQEE++ EQE+ ++ EE +K
Sbjct: 195 RRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEK 254
Query: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE-----EKMREQEE 681
+ EQE E++E++ E+E + E EE + ++E++R+Q+E++ QE E++RE E
Sbjct: 255 LLEQERRQ-EEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLRELERLRELER 311
Query: 682 KMQGQEEKMREQEEKMR------GQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728
++ E + EQ + R E K Q E+ + EK G EE R E
Sbjct: 312 MLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSE 364
Score = 99.4 bits (246), Expect = 1e-20
Identities = 82/292 (28%), Positives = 152/292 (52%), Gaps = 34/292 (11%)
Query: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
+R +E + + + Q+ + + K Q E + + E++++ +R+E E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELES 175
Query: 576 MREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE-- 622
+ Q + E QEE++REQEE++ EQEE++ EQEE++ EQEE++ EQE
Sbjct: 176 VGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEER 235
Query: 623 --EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
E++K+ QE ++ E+ EK+ EQE + E++E++ E+E + E EE + ++E++R+Q+
Sbjct: 236 LCEQEKLPGQERLL-EEVEKLLEQERRQ-EEQERLLERERLLDEVEELL--EQERLRQQD 291
Query: 681 EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE---RIRDQKEK 737
E++ Q+E +RE E + G E + E G EE+ + + ++ Q ++
Sbjct: 292 ERL-WQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350
Query: 738 MQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAG----GEAGEGSPQDNP 785
+++ E R SE V G+ P G G+AG +PQ++P
Sbjct: 351 LEKSGGAEEPRGSESAAAARPV------PGAPVPQGAWMCGQAG-WTPQEHP 395
Score = 97.4 bits (241), Expect = 5e-20
Identities = 68/213 (31%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Query: 366 ERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 424
E+L+++ +R++ E + Q + E ++ R +EE +REQEE++++QEE + E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN--RRQEERLREQEERLREQEERLHE 217
Query: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
QEE RL EQ+E+L EQE+ ++EK+ QE + + E++ QE++ QE++ E+
Sbjct: 218 QEE------RLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLER 271
Query: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM----WQQEEKMREEK 540
E + E EE + +++++ Q+ER+W+Q E LRE ER+RE ++M W+ + R E
Sbjct: 272 ERLLDEVEELL--EQERLRQQDERLWQQ-ETLREL-ERLRELERMLELGWEALYEQRAEP 327
Query: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
++ +E + + ++ E++++E EK EE
Sbjct: 328 RSGFEELNN-ENKSTLQLEQQVKELEKSGGAEE 359
Score = 97.1 bits (240), Expect = 6e-20
Identities = 72/238 (30%), Positives = 129/238 (54%), Gaps = 42/238 (17%)
Query: 386 EKMQEEERIRERE-----KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
E++Q+E +E ++++ E E + ++QEE + EQEE RL EQ+E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEE------RLREQEE 213
Query: 441 KLWEQ-EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
+L EQ E++ EQEE++ EQEE++ +QE++ GQE+ + EK+ EQE + EQE + +
Sbjct: 214 RLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL--ER 271
Query: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
+++ D+ E + EQ ERLR+++ER +WQQ E +RE
Sbjct: 272 ERLLDEVEELLEQ-ERLRQQDER------LWQQ---------------------ETLREL 303
Query: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
ER+RE E+ + E + EQ + + E++ + + + E++++E E+ +E +
Sbjct: 304 ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 361
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 174 bits (440), Expect = 4e-43
Identities = 138/544 (25%), Positives = 277/544 (50%), Gaps = 25/544 (4%)
Query: 245 EQEKKIRKQE-EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE----L 299
E+ +++R+Q+ E+M + ER+ Q + EE+ R+ +R QE+ ++QE+E +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRND--DDEEEAARERRRRARQERLRQKQEEESLGQV 62
Query: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
+Q ++ Q + ++E K ++ +E + + E+ +Q R QE R +E
Sbjct: 63 TDQVEVNAQNS-VPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
D L RM+ E EK ++ E +ER + E T Q+ + E
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181
Query: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
EN E +EKE +++ P++ Q ++ +E+ QEE + + + +QE
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQE 241
Query: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE 539
+ REQ EKM +++++ + E E +ER R K E + KK+ + ++ E
Sbjct: 242 EEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAE---QDKKIADERARIEAE 298
Query: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599
+K QE++ + EE+ ERMRE EK+ EE + ++E+E++ E+ ++++E+E++ E
Sbjct: 299 EKAAAQERERREAEER----ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354
Query: 600 QEEKMQEQEEKMWEQEEK-MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658
+ ++++E+E++ E+ ++ E+EE+ K++EQ+ +E+K QE K+ + EK+ ++
Sbjct: 355 ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI--KGEKVEQK 412
Query: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM 718
E E+K QE+K++ K QG+E+ + Q ++ + QE+K ++E++ ++EK+
Sbjct: 413 IEGKWVNEKK--AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEI--KDEKI 468
Query: 719 WGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGE 778
+E +E+ + D+K+ E ++ E + SV+ + E
Sbjct: 469 KKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDT---KEAE 525
Query: 779 GSPQ 782
G+PQ
Sbjct: 526 GAPQ 529
Score = 167 bits (423), Expect = 4e-41
Identities = 151/585 (25%), Positives = 292/585 (49%), Gaps = 66/585 (11%)
Query: 162 EELTKERDALSLELYRN---TITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLE 218
EE ++R +LE + TIT+ L + +Q AE+E +E KE K +
Sbjct: 104 EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT--AENETTE-----KEEKSESR 156
Query: 219 RAKFLLPQVQTNT--LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE 276
+ ++ + + +T T Q+ WR EE ++++K+ ++EE+ ++ + E + ++ +E+
Sbjct: 157 QERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS-IGENQVEVMVEEK 215
Query: 277 KMRRQEKRL-------------REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
QE+ + +QE+E + E+ +K+ E++++ E E E E
Sbjct: 216 TTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAE 275
Query: 324 EKMR---EQEEKMWRQ------EERLWEQEKQMREQEQK--MRDQEERMWEQDERLREKE 372
E+ R EQ++K+ + EE+ QE++ RE E++ MR++E+R E+ +R++E+E
Sbjct: 276 ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE 335
Query: 373 ERMREQEKMWEQEEKM--QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 430
+R E+ + ++EEK +E +RI+E EK+ EE + R +EE+ K EE ++ K+
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEE---QKRNKQL 392
Query: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
++++ Q+ K+ + EK++++ E W E+K ++ + KK ++ + Q +
Sbjct: 393 EEKKHAMQETKI-KGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451
Query: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
QE+K +++++ +DE+++ K++ +E+ K + +K E K+Q E T
Sbjct: 452 QEDKPTFKKEEI---------KDEKIK-KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTH 501
Query: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
+ R R +E E + E + +E + R E + E E+ Q+Q+E
Sbjct: 502 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEA 561
Query: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE---KMREQEE 667
E EE ++EE K+ E+E EQ K +E + K+ E+EEK R +EE + E E
Sbjct: 562 ALELEELKKKREERRKVLEEE----EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE 617
Query: 668 KMQGQEEKMREQEEK------MQGQEEKMREQEEKMRGQEEKMWG 706
K Q E ++K +G K+ E+ E + +K G
Sbjct: 618 KRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSG 662
Score = 163 bits (413), Expect = 5e-40
Identities = 153/629 (24%), Positives = 307/629 (48%), Gaps = 70/629 (11%)
Query: 162 EELTKERDALSLELYRNTITNEEL--KKKNAELQEKLRLAESEKS------EIQLNVKEL 213
EE+ E + ++ + RN EE +++ QE+LR + E+S ++++N +
Sbjct: 16 EEMRLEAERIAYQ--RNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNS 73
Query: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE----------- 262
E AK Q E + E R +E++ ++ +E + RQ+E
Sbjct: 74 VPD-EEAKTTTTNTQVEGDDEAAFL-ERLARREERRQKRLQEALERQKEFDPTITDASLS 131
Query: 263 ---RLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319
R + + E EK + E R E E E + ++ R+ EE +E +EK
Sbjct: 132 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK- 190
Query: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
E+EE+ + + + + + +EK QE+ + + E +++EER + +
Sbjct: 191 -EEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSD 249
Query: 380 KMWEQEEKMQEEERIR---EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
++ EKM+EE++ R ER + EE E ++ +++K E E EEK Q+R
Sbjct: 250 EI-SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERER 308
Query: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
+ E E+E+M+E+E++ E+ ++I+++E+ +E+ ++++E+E + E+ ++++
Sbjct: 309 REAE---ERERMREEEKRAAEERQRIKEEEKRAAEER-----QRIKEEEKRAAEERQRIK 360
Query: 497 DQEQKMWDQEERMWEQDERLREKEERMR----EQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
++E++ ++ +R ++E + EE+ R E+KK QE K++ EK Q+ E K W
Sbjct: 361 EEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK-WVN 419
Query: 553 EEKMREEERMREREKKMREEE-EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611
E+K +E++ KK EE+ ++ + EK+QE + +++E K +EK+++ +E
Sbjct: 420 EKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIK----DEKIKKDKEPK 475
Query: 612 WEQEEKMWEQE--EEDKMQEQEEMMWEQEEK--------------MQEQEEKMWEQEEKM 655
E + M ++ E K Q E M + + +E E + K
Sbjct: 476 EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR 535
Query: 656 REQEEKMREQEEKMQGQEEKMREQEEKMQGQE-EKMREQEEKMRGQEEKMWGQEE---KM 711
E+ + R + E + ++ K ++QE ++ +E +K RE+ K+ +EE+ QEE K+
Sbjct: 536 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL 595
Query: 712 WGQEEKMWGQEEMREKEERIRDQKEKMQE 740
+EEK +EE+ + ++++KM E
Sbjct: 596 REEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Score = 160 bits (406), Expect = 3e-39
Identities = 132/509 (25%), Positives = 265/509 (52%), Gaps = 42/509 (8%)
Query: 156 KADRY-IEELTKERDALSLELYRNTITNE-ELKKKNAELQEKLRLAESEKSEIQLNVKEL 213
+ +RY IEE + +R+ N+ E K+K E +EK + ++++++ V+E
Sbjct: 156 RQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEE- 214
Query: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
K + + ++ ++ + E +QEEE REQ EKM +++ E E E
Sbjct: 215 KTTESQEETVVMSLKNGQISSEEPKQEEE-REQGSDEISHHEKMEEEDKERAEAERARLE 273
Query: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
EE+ E+ EQ+K++ ++ + ++K QE + +E EE+ E+MRE+E++
Sbjct: 274 AEER----ERIKAEQDKKIADERARIEAEEKAAAQERERREAEER-----ERMREEEKRA 324
Query: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE--QEKMWEQEEKMQEE 391
+ +R+ E+EK+ E+ Q+++++E+R E+ +R++E+E+R E Q E+EEK + E
Sbjct: 325 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384
Query: 392 ERIREREKKMREEEETMREQE---EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448
E ++R K++ E++ M+E + EK++++ E W E+K Q++KL
Sbjct: 385 E--QKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK--------AQEDKLQTAVLK 434
Query: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
++ EEK K++ + E ++K +++E+++ D+ +++++ +++ + D+++
Sbjct: 435 KQGEEK----GTKVQAKREKLQEDKPTFKKEEIK---DEKIKKDKEPKEEVKSFMDRKKG 487
Query: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
E + E + + R T+E E + K EE R R E +
Sbjct: 488 FTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETE 547
Query: 569 MREEEEMMREQEEKMQEQEE--KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626
E E++ ++Q+E E EE K RE+ K+ E+EE+ ++QE E + K+ E+EE+ +
Sbjct: 548 SEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE----EADRKLREEEEKRR 603
Query: 627 MQEQ-EEMMWEQEEKMQEQEEKMWEQEEK 654
++E+ E E EK Q+ E ++K
Sbjct: 604 LKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Score = 82.4 bits (202), Expect = 2e-15
Identities = 106/519 (20%), Positives = 240/519 (46%), Gaps = 54/519 (10%)
Query: 9 PHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHS 68
P M T +N+ E ++K ++ RQ + T TK + N+ + E +
Sbjct: 133 PSRRMQNDTAENETTEKEEK-SESRQERYE-IEETETVTKSYQKNDWRDAEE------NK 184
Query: 69 PEDEKKASHQHQEALRREIEAQDHTIRILTCQKT---ELETALYYSQDAARKFEDGNLGE 125
ED++K + ++ R I ++ + ++ +KT + ET + ++ E+ E
Sbjct: 185 KEDKEKEEEEEEKPKRGSIG--ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEE 242
Query: 126 SKDLAGR--LHHSWHFAGELQRA------LSAVSTWHKKADRYIEELTKERDALSLELYR 177
++ HH + +RA L A KA++ +++ ER + E
Sbjct: 243 EREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQD-KKIADERARIEAE--- 298
Query: 178 NTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 237
+E +++ AE +E++R E +E + +KE +++ + + + + +E
Sbjct: 299 EKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 358
Query: 238 RQEEE-----------LREQEK-KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL 285
+EEE E+EK K+ +Q+ +E++ QE K++ ++ + + + K +
Sbjct: 359 IKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWV 418
Query: 286 REQEKELREQEKELREQKKLREQE-EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
EK+ +E + + KK E++ ++Q + EK+ E + +++E K +E++ +++
Sbjct: 419 --NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIK----DEKI-KKD 471
Query: 345 KQMREQEQKMRDQEERMWEQDERLRE-KEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
K+ +E+ + D+++ E + E +++ E + + + +E +
Sbjct: 472 KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTF---SRPGGRASVDTKEAEGAP 528
Query: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
+ E + EE +++ E E EE E +Q+ E +L E +K +E+ K+ E+EE+ R
Sbjct: 529 QVEAGKRLEELRRRRGET--ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRR 586
Query: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
QEE ++K+ +E+ R ++++ + + ++ QKM
Sbjct: 587 KQEE---ADRKLREEEEKRRLKEEIERRRAEAAEKRQKM 622
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 170 bits (430), Expect = 6e-42
Identities = 107/419 (25%), Positives = 228/419 (54%), Gaps = 18/419 (4%)
Query: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
E R++E++ R+++ + R+ +R RE+ RE++ +R R R++++E + + R
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERR---REKDRHRKRDRHRERQRDREKERERQTDR 111
Query: 301 EQKKLREQEEQMQEQEEKMWEQE-EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
E+ + RE+E Q++ E+ E+E E+ R+++ R+ ER + EK+ Q + R ++
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
Query: 360 RMWEQDERLREKE-ERMREQEKMWEQEEKMQEE--ERIREREKKMREEEETMREQEEKMQ 416
Q ER REK + RE+E+ E+E K ++ ER RERE++ E ET R+++ +
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 417 KQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
+ + E+E EK+ +++R E++ E++K +E+E ++ + + E K+
Sbjct: 232 RDRQRKTEREREKQAERERASERET---ERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
Query: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK 535
R E+ RE E + Q E+ R++E+ + ER ER RE+E + ++ ++ E+
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERER-----ERERERERQRETERDREKERER 343
Query: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
R+ + ++E+ E R+ ER RERE++ + + RE+EE+ ++++ +++ E
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERE--RDRQSAREREERERDRDRDRQKERE 401
Query: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
+ E++ Q + EK E+E+ + ++ +E+E+ + ++ ++ + + Q ++
Sbjct: 402 RQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 167 bits (423), Expect = 4e-41
Identities = 108/447 (24%), Positives = 244/447 (54%), Gaps = 24/447 (5%)
Query: 260 QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319
QE R G+ + + R+ R +E+E+ RE+ + RE + RE+ + +++ K
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRRE-KDRHRKR 91
Query: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQ 378
E+ R++E++ RQ +R E+++Q ++ + +++E + ER R+++ + RE+
Sbjct: 92 DRHRERQRDREKERERQTDR--ERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149
Query: 379 EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438
E+ + E +E ER +RE++ + E +E+E +E+N E+ E+E Q+++ +
Sbjct: 150 ERQRDAE---KERERQTDRERQRQTERNRQKERE-----REKNRQERRERERQREKENKT 201
Query: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498
+++ E+ + +E+E + + E+ R + +++K R+ + + + ++ E+E + RD+
Sbjct: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE-RDK 260
Query: 499 EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558
E+ + ER ++D R+KE + +K ++ E+ RE ++ +E+++ + E+ RE
Sbjct: 261 ER----ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR----ERERERE 312
Query: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618
R RERE++ E E RE E +++ E+ R+++ +M + + +E + + E+
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
Query: 619 WEQE-EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 677
E+E + +E+EE +++ Q++ E+ E++ + + EK RE+E+ + + + R
Sbjct: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER 432
Query: 678 EQE-EKMQGQEEKMREQEEKMRGQEEK 703
+E EK +G+E Q ++ G++ K
Sbjct: 433 GREREKQKGRERDRERQTDRQAGRQRK 459
Score = 167 bits (422), Expect = 5e-41
Identities = 106/462 (22%), Positives = 232/462 (50%), Gaps = 28/462 (6%)
Query: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
RQ+ER +EK+ E+E + + R ++ + ER R++EK + E+ + ER
Sbjct: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK---ERERQTDRERD 114
Query: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
R+REK+ ++E RE E + ++ + + + + +Q+ +++E+ ++E+ ++ E
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
++ E+ ++++E +E++ ++ K ++ + + E+ R+ E + + + E+D
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
+ + + ER ++ ++ E + +K+ + + + D++ + +E ER +R+++ R E +
Sbjct: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Query: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM 634
RE E K + Q E+ RE+E + E+ +E+E + + E+ E+E E K + Q EM
Sbjct: 295 --RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 635 WE------QEEKMQEQEEKMWEQE---EKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
E +E + Q + E+ E+E + RE+EE+ R+++ Q + E+ E++ Q
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Query: 686 QEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745
+ EK RE+E+ + + G+E EK G+E RE++ + +++ + L +
Sbjct: 413 ETEKQREREKDRESERGRERGRE------REKQKGRERDRERQTDRQAGRQRKRSTLYVN 466
Query: 746 EERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTA 787
PP + + P G + SP+D A
Sbjct: 467 P--------PPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAA 500
Score = 166 bits (419), Expect = 1e-40
Identities = 115/469 (24%), Positives = 243/469 (51%), Gaps = 44/469 (9%)
Query: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE-GKMREQEEKMRRQEK 283
P Q + + + + ++ +++ +Q+E+ R+E+R E+E + RE+ + R K
Sbjct: 31 PGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRK 90
Query: 284 RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE-EKMREQEEKMWRQEERLWE 342
R R +E++ R++EKE RE++ RE++ Q +++ + E+E E RE E RQ + E
Sbjct: 91 RDRHRERQ-RDREKE-RERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
Query: 343 QEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQEEKMQEEERIREREKKM 401
+E+Q ++++ R + Q ER R+KE ER + +++ E+E + ++E + +R +
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
Query: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
E E RE E + +++ + E++ +Q++ ++EK E+E+ E+E + ++ E+
Sbjct: 209 GRERERERETETETERKRQTDRERD----RQRKTEREREKQAERERASERETERDKERER 264
Query: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521
RD++ +++ + +++E++ + +R E+D K E
Sbjct: 265 ERDRDR----------------------DRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 522 RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 581
R RE+ E+ RE + +E+E++ + E+ RE ER RE+E++ + + + ++E
Sbjct: 303 RQRER-------ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
Query: 582 KMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM 641
Q E R+ E E+E + + + E+EE+ E++ + Q++ E E++
Sbjct: 356 NRQTGREGRRQAER---ERERERERDRQSAREREER--ERDRDRDRQKERERQTEKDRDG 410
Query: 642 QEQEEKMWEQEEKMREQEEKMREQE-EKMQGQEEKMREQEEKMQGQEEK 689
Q + EK E+E+ + + R +E EK +G+E Q ++ G++ K
Sbjct: 411 QRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 162 bits (409), Expect = 2e-39
Identities = 115/457 (25%), Positives = 232/457 (50%), Gaps = 48/457 (10%)
Query: 265 REQEGKMRE---QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE 321
++ +G RE Q+E+ RR+EKR E+E + + + + +++ + R++ + Q EK E
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
Query: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
++ RE++ + ++ R E+E++ + ++ RD++ + ER R+ E +E+E+
Sbjct: 107 RQTD-RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE---KERERQ 162
Query: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
++E + Q E R R+K+ E+ +E + Q+++EN E E ++R
Sbjct: 163 TDRERQRQTE---RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER------- 212
Query: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
E+E+ E E + Q ++ RD++ +E+ EK E+E + E RD+E+
Sbjct: 213 --ERERETETETERKRQTDRERDRQRKTERER-----EKQAERERA--SERETERDKER- 262
Query: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
+ ER ++D R+KE + +K ++ E+ RE ++ +E R+ ER
Sbjct: 263 ---ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE------------RQRER 307
Query: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
RERE+ + E E RE+E + Q + E+ RE+ E+E K + Q E E+ + +
Sbjct: 308 ERERERNRKRERERERERERERQRETERDREK-----ERERKRKRQTEMDRERNRQTGRE 362
Query: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
+E+E + +E+EE+ +++ +++ E+ E++ Q + EK RE+E+
Sbjct: 363 GRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREK 422
Query: 682 KMQGQEEKMREQE-EKMRGQEEKMWGQEEKMWGQEEK 717
+ + + R +E EK +G+E Q ++ G++ K
Sbjct: 423 DRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 154 bits (389), Expect = 3e-37
Identities = 112/439 (25%), Positives = 226/439 (51%), Gaps = 27/439 (6%)
Query: 154 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL 213
HK AD E ++++ R T + K++ +++ R + + + KE
Sbjct: 46 HKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105
Query: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
+R+ +R E RQ E+ R ++K+ ++ E R+ ER R+++ +
Sbjct: 106 ERQTDR---------------ERDRQREKERNRQKERERETE---REGERGRDRQTDGQR 147
Query: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
+ E+ R EK RE++ + Q + R ++K RE+E+ QE+ E+ ++E++ + ++
Sbjct: 148 ERERQRDAEKE-RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
Query: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQE-EKMQEE 391
R ER E+E + + ++ D+E + ER REK+ ER R E+ E++ E+ +E
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
+R R+R+++ +E E R+ + K Q++ E E E K +Q+ ++E+ ++E+ +E+
Sbjct: 267 DRDRDRDRRQKERE---RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER 323
Query: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-REQEDQMWEQEEKMRDQEQKMWDQEERMW 510
E + Q E RD+E+ +E+K RQ +M RE+ Q + + ++E++ + +R
Sbjct: 324 ERERERQRETERDREKE--RERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381
Query: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570
++ RE++ QK+ +Q EK R+ ++ E++++ E R ER REREK+
Sbjct: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
Query: 571 EEEEMMREQEEKMQEQEEK 589
E + R+ + + Q ++
Sbjct: 442 RERDRERQTDRQAGRQRKR 460
Score = 149 bits (375), Expect = 1e-35
Identities = 96/379 (25%), Positives = 207/379 (54%), Gaps = 25/379 (6%)
Query: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 429
+ ER R++E+ +E++ E E R+RE++ ++ R++ + Q+ E ++ E++
Sbjct: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE---KERERQ 108
Query: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
++R Q+EK E+ + +E+E + + E+ RD++ +E+ E+ R+ E +
Sbjct: 109 TDRER-DRQREK--ERNRQKERERETEREGERGRDRQTDGQRER-----ERQRDAEKERE 160
Query: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Q ++ R ++ + Q+ER E+++ +E+ ER R+++K + E++ E + +E+E++T
Sbjct: 161 RQTDRERQRQTERNRQKER--EREKNRQERRERERQREKENKTEDRHSERGRERERERET 218
Query: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
+ E+ R+ +R R+R++K E E E+E + + E+ +E+E + ++ + Q+E
Sbjct: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Query: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
+ E++ + K Q + E E E K + Q E+ E+E + + E+ RE+E +
Sbjct: 279 R---------ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
Query: 670 QGQEEKMREQE-EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728
Q + E+ RE+E E+ + ++ +M + + G+E + + E+ +E E RE+
Sbjct: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARE-REER 388
Query: 729 ERIRDQ-KEKMQERLPEHE 746
ER RD+ ++K +ER E +
Sbjct: 389 ERDRDRDRQKERERQTEKD 407
Score = 133 bits (335), Expect = 6e-31
Identities = 94/362 (25%), Positives = 186/362 (51%), Gaps = 18/362 (4%)
Query: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE---QKEKLWEQEK 447
+E R R ++ ++E QK+ E E+ + E + R E +K++ ++++
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-----EKMREQEDQMWEQEEKMRDQEQKM 502
+E++ ++ E+ D+E +EK+ RQ E RE E Q + R++E++
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Query: 503 WDQEERMWEQD-ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
++ER + D ER R+ E +++++ + ++ RE ++ +E+E KT D R ER
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED-----RHSER 208
Query: 562 MREREKKMREEEEMMRE-QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE 620
RERE++ E E R+ Q ++ ++++ K + EK E+E + + E+ E+E +
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDR 268
Query: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
+ D+ Q++ E + + K Q + E+ E E K Q E+ RE+E + + E+ RE+E
Sbjct: 269 DRDRDRRQKERER--QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 681 EKMQGQEEKMREQE-EKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
+ Q + E+ RE+E E+ R ++ +M + + G+E + + E + ER R + +
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 740 ER 741
ER
Sbjct: 387 ER 388
Score = 127 bits (319), Expect = 4e-29
Identities = 98/403 (24%), Positives = 209/403 (51%), Gaps = 36/403 (8%)
Query: 154 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL 213
H+K DR+ E ++RD E R T + +++ ++K R E+E+ + ++
Sbjct: 88 HRKRDRHRE---RQRDR-EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
Query: 214 --KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
+R+ ER + + + T +E RQ E R++E++ K ++ R+ ER RE+E K
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQ-RQTERNRQKEREREKNRQER-RERERQREKENKT 201
Query: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
++ + R+ +R RE E E + + RE+ + R+ E + ++Q E+ E+ E+++
Sbjct: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE-RASERETERDK 260
Query: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE-----QEE 386
+ R+ +R +++++ +E+E++ + +R E+D K ER RE+E+ E + E
Sbjct: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
Query: 387 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
+ +E ER R+RE E + +E+E K ++Q E E+ + ++ R ++E+ E+E
Sbjct: 321 RERERERERQRE----TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
Query: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
+ ++ E+EE+ RD++ R+++ + Q EK RD +++ Q
Sbjct: 377 RDRQSAR---EREERERDRD---------------RDRQKERERQTEKDRDGQRETEKQR 418
Query: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
ER +++ + R RE++K +++ + + +++ Q K++
Sbjct: 419 EREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRS 461
Score = 123 bits (309), Expect = 6e-28
Identities = 131/476 (27%), Positives = 223/476 (46%), Gaps = 65/476 (13%)
Query: 11 PMMSEKTRQNKLAEAKKKFT-DYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSP 69
P E R+ L +A K D R+ N R + ++++ T ET
Sbjct: 31 PGSQESPRRRGLGQAHKDADGDDRERN------RQKERERRREKRQTERETDRKRERRRE 84
Query: 70 EDEKKASHQHQEALR-REIEAQDHTIRILTCQKTELETALYYSQDAARKFE-DGNLGESK 127
+D + +H+E R RE E + T R Q+ E ++ R+ E +G G +
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQR---EKERNRQKERERETEREGERGRDR 141
Query: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKK 187
G+ E +R A ++ DR + T+ RN E +K
Sbjct: 142 QTDGQR--------ERERQRDAEKERERQTDRERQRQTE----------RNRQKEREREK 183
Query: 188 KNAELQEKLRLAESE-KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
E +E+ R E E K+E + + + +R+ ER + +T T E RQ + R++
Sbjct: 184 NRQERRERERQREKENKTEDRHSERGRERERER------ETETET---ERKRQTDRERDR 234
Query: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLR 306
++K ++ EK Q ER R E RE E R+ +R R+++++ R++E+E + +K +
Sbjct: 235 QRKTEREREK---QAERERASE---RETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
Query: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 366
+ E+ +E E K Q E+ RE+E R+ ER E+E++ Q + RD+E+ E++
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERER--ERERERERQRETERDREK---ERER 343
Query: 367 RLREKEERMREQEKMWEQEEKMQ-EEERIREREK---KMREEEETMREQEEKMQKQEENM 422
+ + + E RE+ + +E + Q E ER RERE+ RE EE R+++ QK+ E
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER- 402
Query: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Q EK+ QR + EK E+EK +E E E+ R++E+ G+E+ RQ
Sbjct: 403 --QTEKDRDGQR---ETEKQREREKDRESE----RGRERGREREKQKGRERDRERQ 449
Score = 112 bits (279), Expect = 2e-24
Identities = 73/320 (22%), Positives = 163/320 (50%), Gaps = 7/320 (2%)
Query: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
+R P +E + Q ++ + E+ R +E +EK+ +E R++E + +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE-QEKKTWD 551
+ RD+ ++ Q +R E++ + + +R RE+++ Q+E + E++ + ++++T
Sbjct: 88 HRKRDRHRER--QRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
Query: 552 QEEKMREEERMREREKKM-REEEEMMREQEEKMQEQEEKMRE--QEEKMWEQEEKMQEQE 608
Q E+ R+ + +ERE++ RE + +K +E+E+ +E + E+ E+E K +++
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
Query: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
+ + E+ E E E + + Q + +++ K + + EK E+E + E+ +E+E +
Sbjct: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
Query: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728
++ R Q+E+ + + K + + E+ R E K Q E+ + E+ +E RE+E
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERE-RERERNRKRERERERE 324
Query: 729 ERIRDQKEKMQERLPEHEER 748
Q+E ++R E E +
Sbjct: 325 RERERQRETERDREKERERK 344
Score = 79.3 bits (194), Expect = 1e-14
Identities = 52/225 (23%), Positives = 111/225 (49%), Gaps = 11/225 (4%)
Query: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
+E R Q + D E+ R++ER R REK+ E RE + K + + EK R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTE-----RETDRKRERRREKDRH 88
Query: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE-EKMQEQEEKMWEQ 651
++ + ++ +E+E + E+ ++E+E Q++ E E+E E+ ++++ +
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
Query: 652 EEKMREQEEKM-----REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
E+ R+ E++ RE++ + + +K RE+E+ Q + E+ R++E++ + ++
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
Query: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
E+ +E + + + + ER R +K + + ER SE
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Score = 69.7 bits (169), Expect = 1e-11
Identities = 76/338 (22%), Positives = 152/338 (44%), Gaps = 37/338 (10%)
Query: 43 RATDTKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKT 102
R D +K++ +E E E++ + Q + R+ E ++ T + +
Sbjct: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
Query: 103 ELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIE 162
E E + RK + +D + E +RA + K+ +R
Sbjct: 211 ERERERETETETERKRQTDR---ERDRQRKTEREREKQAERERASERETERDKERER--- 264
Query: 163 ELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKF 222
E ++RD + R T+ + +++ +E R E ++ + + KR+ ER +
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER- 323
Query: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE---GKMREQEEKMR 279
+ E RQ E R++EK+ R+ +R R+ E + R+ + R
Sbjct: 324 ----------ERERERQRETERDREKE---------RERKRKRQTEMDRERNRQTGREGR 364
Query: 280 RQEKRLREQEKE-----LREQEKELREQKKLREQEEQMQEQEEKMWEQE-EKMREQEEKM 333
RQ +R RE+E+E RE+E+ R++ + R++E + Q ++++ ++E EK RE+E+
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD- 423
Query: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371
R+ ER E+ ++ +Q+ + RD+E + Q R R++
Sbjct: 424 -RESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 57.0 bits (136), Expect = 7e-08
Identities = 83/341 (24%), Positives = 144/341 (42%), Gaps = 44/341 (12%)
Query: 15 EKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKK 74
E+ RQ + +++ TD + R T+ ++K E E E K
Sbjct: 148 ERERQRDAEKERERQTDRER-------QRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 75 ASHQHQEALR-REIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRL 133
+H E R RE E + T +TE + +D RK E E + A R
Sbjct: 201 TEDRHSERGRERERERETET-------ETERKRQTDRERDRQRKTER----EREKQAERE 249
Query: 134 HHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALS-LELYRNTITNEELKKKNAEL 192
A E + + DR + KER+ + + R T + E ++K
Sbjct: 250 R-----ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 193 QEK--------LRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
+E+ R E E+ + +E +R E+ + + QT +E + E R
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364
Query: 245 EQEKKIRKQEEKMWRQEERLREQEGKMRE---QEEKMRRQEKRLREQEKELREQEKELRE 301
Q ++ R++E + RQ R RE+ + R+ Q+E+ R+ EK Q RE EK+ RE
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ----RETEKQ-RE 419
Query: 302 QKKLREQE---EQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
++K RE E E+ +E+E++ + ++ R+ + + RQ +R
Sbjct: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 160 bits (405), Expect = 5e-39
Identities = 147/540 (27%), Positives = 277/540 (51%), Gaps = 36/540 (6%)
Query: 238 RQEEELREQEKKIRKQE---EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE 294
+QEE+ K + +QE ++ QE+ L++Q + E+ +K E++L+ QEK R+
Sbjct: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLK-QEKTQRD 116
Query: 295 QE--KELREQKKLREQE--EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
Q+ K+L E+KKL +Q+ +++ +++E++ ++E++ E E+ + L +QE Q++
Sbjct: 117 QQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHP 176
Query: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
EQ ++ + + EQ E E E+ Q ++ EQ+E E +E + ++ E++E
Sbjct: 177 EQ--QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE---G 231
Query: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 470
Q E Q+QE + E++E Q + +Q+ +L E + Q E EQ +++ E+ G
Sbjct: 232 QLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEG 291
Query: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530
Q K + +QEK E +Q Q + + QE Q + + +Q+ +L + EE+ + K +
Sbjct: 292 QLKHLDQQEKQPELPEQQMGQLKHLEQQE----GQPKHLEQQEGQLEQLEEQEGQLKHLE 347
Query: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
QQE ++ + + Q Q ++++ E+ + + K + EEE ++ + QE + K
Sbjct: 348 QQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQ--QEGQLKH 405
Query: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Q+E EQ+E+ E E+ Q + + EQE + K EQ++ E E+ Q + K E
Sbjct: 406 LVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQ-QVGQPKNLE 464
Query: 651 QEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
QEEK E E+ Q + ++ QE ++ E E+ GQ + + EQ+EK E+ GQ +
Sbjct: 465 QEEKQLELPEQQEGQVKHLEKQEAQL-ELPEQQVGQPKHL-EQQEKHLEHPEQQDGQLKH 522
Query: 711 MWGQEEKMWGQEEMREKEER-----IRDQKEKMQERLP---------EHEERCSEPCLPP 756
+ QE ++ E+ + + E+ Q + +Q LP EH+++ E PP
Sbjct: 523 LEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPP 582
Score = 158 bits (399), Expect = 2e-38
Identities = 138/545 (25%), Positives = 286/545 (52%), Gaps = 41/545 (7%)
Query: 230 NTLQEEMWRQEEELREQEKKI---------RKQEEKMWRQEERLREQEGKMREQEEKMRR 280
NT QE+M +Q L +K+ KQEEK + L EQE + +++E
Sbjct: 28 NTHQEQM-KQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEP---- 82
Query: 281 QEKRLREQEKELREQ-EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE--EKMWRQE 337
QE+ L++Q E E+ +K +++L++++ Q +Q K E+E+K+ +Q+ +++ +++
Sbjct: 83 QEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD 142
Query: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
E+L +++Q+ E ++ + + +Q+ +L+ E++ + E +QE +++ E+ +E
Sbjct: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQ-QEG 201
Query: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457
+ ++ E++E E E Q+E E E++ Q LP+Q+E E + QE + ++ E
Sbjct: 202 QLELPEQQEGQLELPE----QQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSE 257
Query: 458 QEE-KIRDQEEMWGQ----EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQ 512
Q+E +++ E GQ E++M + + + +QE Q+ K DQ++K + E+ Q
Sbjct: 258 QQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQL-----KHLDQQEKQPELPEQQMGQ 312
Query: 513 DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
+ L ++E Q K +Q+E E+ + QE + K +Q+E E +E + + E+
Sbjct: 313 LKHLEQQEG----QPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQ 368
Query: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
+ + +Q EK Q Q + + E+E ++ + QE + K Q+E EQ+E +++
Sbjct: 369 QVLQLKQLEKQQGQPKHLEEEEGQL--KHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQ 426
Query: 633 MMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692
+ + + QE + K EQ++ E E+ Q + ++ QEEK E E+ +GQ + + +
Sbjct: 427 VGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLE-QEEKQLELPEQQEGQVKHLEK 485
Query: 693 QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752
QE ++ E+++ GQ + + Q+EK E ++ + + +Q+E + L + + + +P
Sbjct: 486 QEAQLELPEQQV-GQPKHL-EQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQP 543
Query: 753 CLPPS 757
P+
Sbjct: 544 VFAPA 548
Score = 138 bits (348), Expect = 2e-32
Identities = 129/508 (25%), Positives = 264/508 (51%), Gaps = 43/508 (8%)
Query: 183 EELKKKNAELQEKLRLAESEKSEIQLNV----KELKRKLERAKFLLPQVQTNTLQEEMWR 238
+EL++++ E E+ + AE+ + +++ ++L ++LE K LL Q L +E+ +
Sbjct: 85 QELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ----QLDQELVK 140
Query: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE------EKMRRQEKRL-----RE 287
++E+L +++++ + E+ + L +QEG+++ E E +QE +L +E
Sbjct: 141 RDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQE 200
Query: 288 QEKELREQEK---ELREQK----KLREQEE------QMQEQEEKMWEQEEKMREQEEKMW 334
+ EL EQ++ EL EQ+ +L EQ+E Q QE + ++ EQ+E E E+
Sbjct: 201 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQE 260
Query: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Q + L QE Q+ E++M Q + + +Q+ +L+ +++ ++ E +Q +++ E+
Sbjct: 261 GQLKHLEHQEGQLEVPEEQM-GQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQ 319
Query: 395 REREKKMREEE---ETMREQEEKMQ--KQEENMWEQEEKEWQQQRLPEQKE-KLWEQEKM 448
+ K + ++E E + EQE +++ +Q+E E E + Q LPEQ+ +L + EK
Sbjct: 320 EGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQ 379
Query: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Q Q + + E+E +++ + GQ K + +QE EQ+++ E E+ Q + + +QE +
Sbjct: 380 QGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQ 439
Query: 509 M--WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
+ EQ + E E+ Q K +QEEK E + QE + K +++E E + +
Sbjct: 440 LKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQ 499
Query: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626
K E++E E E+ Q + + +QE ++ + E++ + E+ ++ Q+ +
Sbjct: 500 PKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQ-VQDIQPA 558
Query: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
+ + E++ E + Q+QE + W + K
Sbjct: 559 LPTKGEVLLPVEHQQQKQEVQ-WPPKHK 585
Score = 130 bits (326), Expect = 7e-30
Identities = 122/501 (24%), Positives = 255/501 (50%), Gaps = 38/501 (7%)
Query: 185 LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
L ++ E Q+K E ++ E+Q E + ++A+ P+ Q L++E +++++L
Sbjct: 70 LPEQECEQQQK----EPQEQELQQQHWEQHEEYQKAEN--PEQQ---LKQEKTQRDQQLN 120
Query: 245 ---EQEKKIRKQE--EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
E+EKK+ Q+ +++ +++E+L ++ ++ E E+ K L +QE +L+ E++
Sbjct: 121 KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ- 179
Query: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
E + ++ EQ+E E E+ Q E +QE +L E+Q E + ++ +Q+E
Sbjct: 180 -------EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ--EGQLELPEQQE 230
Query: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
E ++ + E +QE E E+ + + + E ++ E E Q + +++QE
Sbjct: 231 GQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQE 290
Query: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
+ +++E Q + +Q +L E+ + Q + + +QE ++ EE GQ K + +QE
Sbjct: 291 GQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQE 350
Query: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR-- 537
E + E + + +Q+ Q E+ Q + L E+E ++ K + QQE +++
Sbjct: 351 GQLEHLEHQ-EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQL---KHLVQQEGQLKHL 406
Query: 538 --EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEEKMREQE 594
+E + ++QE++ E+++ + + + E+E +++ E+ + E + Q + K EQE
Sbjct: 407 VQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQE 466
Query: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
EK E + EQ+E + EK Q E + Q + EQ+EK E E+ Q +
Sbjct: 467 EKQLE----LPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKH 522
Query: 655 MREQEEKMREQEEKMQGQEEK 675
+ +QE ++++ E++ +GQ E+
Sbjct: 523 LEQQEGQLKDLEQQ-KGQLEQ 542
Score = 82.0 bits (201), Expect = 2e-15
Identities = 113/489 (23%), Positives = 226/489 (46%), Gaps = 42/489 (8%)
Query: 8 PPHPMMSEKTRQ----NKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTS 63
P + EKT++ NK E +KK D + KK+++ PE
Sbjct: 104 PEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLE--LPEQQEG 161
Query: 64 EGCHSPEDEKKASHQHQEALRREI-EAQDHTIRILTCQKTELETALYYSQDAARKF---E 119
H + E + H Q+ + E+ E Q+ + + Q+ +LE L Q+ + +
Sbjct: 162 HLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLE--LPEQQEGQLELPEQQ 219
Query: 120 DGNLGESKDLAGRLHHSWHFAGEL-----QRALSAVSTWHKKADRYIEELTKERDALSLE 174
+G L + G+L G+L Q +S + +++E + + +
Sbjct: 220 EGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQ 279
Query: 175 LYR-NTITNEELKKKNAELQEKL-RLAESEKSEIQ-LNVKELKRK-LERAKFLLPQVQTN 230
+ + + +E + K+ + QEK L E + +++ L +E + K LE+ + L Q++
Sbjct: 280 MGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQ 339
Query: 231 TLQ----EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR 286
Q E+ Q E L QE ++ E+++ Q ++L +Q+G+ + EE+ Q K L
Sbjct: 340 EGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVL-QLKQLEKQQGQPKHLEEE-EGQLKHLV 397
Query: 287 EQE---KELREQEKELREQKKLREQEEQM---------QEQEEKMWEQEEKMREQEEKMW 334
+QE K L +QE +L +Q++ E EQ QE + K EQ++ E E+
Sbjct: 398 QQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQV 457
Query: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Q + L ++EKQ+ EQ+ Q + + +Q+ +L E+++ + + + +QE+ ++ E+
Sbjct: 458 GQPKNLEQEEKQLELPEQQ-EGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQ 516
Query: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ--QQRLPEQKEKLWEQEKMQEQE 452
+ K + ++E +++ E++ + E+ ++ + Q Q LP + E L E Q+++
Sbjct: 517 DGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQ 576
Query: 453 EKIWEQEEK 461
E W + K
Sbjct: 577 EVQWPPKHK 585
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 160 bits (404), Expect = 6e-39
Identities = 177/621 (28%), Positives = 294/621 (47%), Gaps = 64/621 (10%)
Query: 161 IEELTKERDALSLELYRNTITNEELKKKN-----------AELQEKLRLAESEKSEIQLN 209
+E L + D L++ + +NE+ K + EL + L E++ S+
Sbjct: 490 VESLGETTDILNMTHIMSLNSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEE 549
Query: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER---LRE 266
+ E+K K V + E ++E +I EEK ++ + + E
Sbjct: 550 MSEMKE----GKACKQHVSQGIFMTQPATTIEAFSDEEVEI--PEEKEGAEDSKGNGIEE 603
Query: 267 QEGKMREQEEKMRRQEKRLREQEKELREQEKELRE--QKKLREQEEQMQEQEE------- 317
QE + E+ K+ K E + + E+ E K + E E+ + + +
Sbjct: 604 QEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGS 663
Query: 318 ---KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ-KMRDQEERMWEQDERLREKEE 373
+ W+ EE+ + +++K + ER E EK++ E+E+ K RD EE+ E+
Sbjct: 664 SGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQ-----------EQ 712
Query: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 433
+ REQ Q+E+ QE E E E EEEE RE+EE+ + + + E EE E +++
Sbjct: 713 KEREQG---HQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGERE 769
Query: 434 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 493
+ E + K E+ +E+ E+ +Q E ++ E G+EK+ + + E E+ E+EE
Sbjct: 770 K-EEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828
Query: 494 KMRDQEQKMWDQEERMWEQDERLREKEE---RMREQKKMWQQEEKMREEKKTQEQEKKTW 550
++E+ ++EE E++E E+EE + E+ + + EE+ E + E+E+
Sbjct: 829 ---EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG 885
Query: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE-EKMQEQEE 609
+ EE+ E E E + EE E E+EE + EE+ E E + E+E E E E
Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGE 945
Query: 610 KMWEQEEKMWEQEEEDKMQE-QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
E+EE WE EEE+ E +EE E EE E EE E+ E E+EE E EE+
Sbjct: 946 GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE---EEGEGEGEEEEGEEEGEEE 1002
Query: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ-EEMREK 727
+G+EE E EE+ +G+ E E EE G+ E+ G+EE G+E + G+ EE R
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEG-EGEGEEEEGEEE---GEEREKEGEGEENRRN 1058
Query: 728 EERIRDQKEKMQERLPEHEER 748
E +++ K QE E ER
Sbjct: 1059 REEEEEEEGKYQETGEEENER 1079
Score = 145 bits (366), Expect = 1e-34
Identities = 151/579 (26%), Positives = 283/579 (48%), Gaps = 52/579 (8%)
Query: 181 TNEELKKKNAELQEKLRLAES------EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE 234
T E + E+ E+ AE E+ E++ N + +K R + +T L +
Sbjct: 575 TIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKE------KTEILSD 628
Query: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ---EEKMRRQEKRLREQEKE 291
++ + E + K + + E+ + + E+ E EE+ + ++ + R + +
Sbjct: 629 DLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMER 688
Query: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
E EKEL E+++ ++++ + QEQ+E+ +++ ++ E+ +E E+E+ RE+E
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Query: 352 QKMRDQ--EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
++ + EE E+ E REKEE R++E+ +EEK +E E ++ EEEET
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE-----EGDQGEGEEEETEG 803
Query: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
EEK + E E EE + E+ +E+EE E+EE ++EE
Sbjct: 804 RGEEKEEGGEVEGGEVEE---------------GKGEREEEEEEGEGEEEEGEGEEEEGE 848
Query: 470 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529
G+E++ E E+E + E EE+ + E + ++E ++E E EE E +
Sbjct: 849 GEEEE---GEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGE 905
Query: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
+ E + EE+ + E++ + E + EEE E E E EE E E + +E E +
Sbjct: 906 EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE 965
Query: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ-----EQ 644
E+ E E+ E E+EE E EE+ E+E E++ + +EE E EE+ + E
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEV 1025
Query: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKM-REQEEKMQGQEEKMREQEEKMRGQEEK 703
E + E E + E EE+ E+E++ +G+E + RE+EE+ +G+ ++ E+E + + EE
Sbjct: 1026 EGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE- 1084
Query: 704 MWGQEEKMWGQ----EEKMWGQEEMREKEERIRDQKEKM 738
+ + K+ G + K + ++ + + ++Q+ KM
Sbjct: 1085 -YKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKM 1122
Score = 125 bits (315), Expect = 1e-28
Identities = 145/556 (26%), Positives = 254/556 (45%), Gaps = 64/556 (11%)
Query: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
E+ K+ +K+ ++Q Q+ L E E EE + +E K +Q +
Sbjct: 512 EKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQ 571
Query: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR----EQEKMWEQEEKM 388
E ++E ++ E+++ D + E+ E + EE ++ +EK + +
Sbjct: 572 PATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQE-VEANEENVKVHGGRKEKTEILSDDL 630
Query: 389 QEEERIREREKKMREEEETMREQE------------EKMQKQEENMWEQEEKEWQQQRLP 436
++ + E + K E E E E Q +E E+++ + +R
Sbjct: 631 TDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPG 690
Query: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
E +++L E+E+ ++++ + EQE+K R+Q Q+++ E+ E+E E+EE R
Sbjct: 691 EGEKELAEKEEWKKRDGE--EQEQKEREQGH---QKERNQEMEEGGEEEHGEGEEEEGDR 745
Query: 497 DQEQKMWDQ--EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
++E++ + EE E+ E REKEE R++++ +EEK EE E E++ +
Sbjct: 746 EEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG 805
Query: 555 KMREE--------------ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
+ +EE ER E E+ EEEE E+EE E+EE + EE+ E
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Query: 601 E-EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
E E+ E+ E E+EE E EEE + + +EE E E + +E+ E E+EE + E
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE---EGEGEGEEEGEGEGEEEEGEGKGE 922
Query: 660 EKMRE-----QEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
E+ E +EE+ +G+ E + E+ +G+ E E+ E +E + G+E + G+
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE 982
Query: 715 EEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVE-PAG 773
EE+ G+ E E EE ++ E +E E EE G VE
Sbjct: 983 EEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE----------------EEEGEVEGEVE 1026
Query: 774 GEAGEGSPQDNPTAQE 789
GE GEG ++ +E
Sbjct: 1027 GEEGEGEGEEEEGEEE 1042
Score = 118 bits (295), Expect = 3e-26
Identities = 152/605 (25%), Positives = 269/605 (44%), Gaps = 64/605 (10%)
Query: 49 KKKINNG---TNPETT----TSEGCHSPEDEKKASHQHQEALR-REIEAQDHTIRILTCQ 100
K+ ++ G T P TT + E PE+++ A + +E+EA + +++ +
Sbjct: 560 KQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGR 619
Query: 101 KTELETALYYSQDAARKFEDG--NLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKAD 158
K + E D A E ++GE++D G + S W + +
Sbjct: 620 KEKTEILSDDLTDKAEVSEGKAKSVGEAED-----GPEGRGDGTCEEGSSGAEHWQDE-E 673
Query: 159 RYIEELTKERDALSL--ELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRK 216
R E K R + E + EE KK++ E QE +K Q + KE ++
Sbjct: 674 REKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQE-------QKEREQGHQKERNQE 726
Query: 217 LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE 276
+E + +EE R+EEE +E E K EE + E RE+E R++EE
Sbjct: 727 MEEGG---EEEHGEGEEEEGDREEEEEKEGEGK----EEGEGEEVEGEREKEEGERKKEE 779
Query: 277 KMRRQEK--------RLREQEKELREQEKE---------LREQKKLREQEEQMQEQEEKM 319
+ ++EK E+E E R +EKE + E K RE+EE+ E EE+
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Query: 320 WEQEEKMREQEEK----MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 375
E EE+ E EE+ +E E E++ E E + ++E ++E E EE
Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899
Query: 376 REQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE-ENMWEQEEKEWQQQR 434
E E E E + +EEE + E++ E E E+E + + ++ E E+EE EW+ +
Sbjct: 900 GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEE 959
Query: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
+ E E E E+ E E+EE + EE G+E+ +E+ +E+ E EE+
Sbjct: 960 EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE---GEEEGEGEEEGEGEGEEE 1016
Query: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
+ + + EE E +E E+E RE++ ++ + REE++ +E + + +EE
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076
Query: 555 KMREEERMREREKKMREEEEMMRE---QEEKMQEQEEKMREQEEKMWEQEEKMQEQ---- 607
R++ ++ K++ + + Q++ + + +EQ KM Q +++ +
Sbjct: 1077 NERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPSG 1136
Query: 608 EEKMW 612
+K W
Sbjct: 1137 SKKFW 1141
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 155 bits (391), Expect = 2e-37
Identities = 158/695 (22%), Positives = 330/695 (47%), Gaps = 67/695 (9%)
Query: 74 KASHQHQEALRREIEAQDHTIR------ILTCQKTELETALY--YSQDAARKFEDGNLGE 125
KAS + A + E+E + IR + + ++ ELE A + + R+ +
Sbjct: 1931 KASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERV 1990
Query: 126 SKDLAGRLHHSWHFAGELQRALSAVSTWHKKAD--RYIEELTKERDALSLELYRNT---- 179
K LA A + + AL V K + R + E ++ A L+L +
Sbjct: 1991 QKSLAAEEEA----ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 180 ITNEE------LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233
+ EE +++K ELQ+ L+ +S +++ + +R E A+ Q + Q
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 234 -----EEMWRQEEELREQEK----------KIRKQEEKMWRQEERLREQEGKMREQEEKM 278
EE R ++ EQ + K+RK+ E+ R + ++ +R+++
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ--EAARRAQAEQAALRQKQAAD 2164
Query: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
EK + E+ LR++ + +E LR Q E+ Q+ + E+ ++++ + + RQ
Sbjct: 2165 AEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRS 2224
Query: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398
++ E+ +R Q +++ + R+ E + R ++ Q + E+ EKM++ R
Sbjct: 2225 QVEEELFSVRVQMEELSKLKARI-EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARL 2283
Query: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ-----RLPEQKEKLWEQEKM-QEQE 452
+E +R+ E+ Q+ + E+ KE Q RL + E L +Q+++ QEQ
Sbjct: 2284 SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQA 2343
Query: 453 EKIWEQEEKIRDQ--EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
++ E +E++ Q EE G ++ + E R+++ +M + E+++ + +M + R
Sbjct: 2344 RRLQEDKEQMAQQLAEETQGFQRTL---EAERQRQLEMSAEAERLKLRVAEMSRAQARAE 2400
Query: 511 EQDERLREKEERMREQKKMWQ--QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK- 567
E +R R++ E + E+ + +EK+ + + Q +++ E++RE EREK
Sbjct: 2401 EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2460
Query: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ----EEKMQEQEEKMWEQEEKMWEQEE 623
K+++E ++++ + E+MQ +++ QE + +Q E+ Q E+ EQE+ EQ
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 624 EDKMQEQEEMMWEQEEKMQEQEEK-------MWEQEEKMREQEEKMREQEEKMQGQEEKM 676
+D++ + +++ EQ+ + Q+ E++ M E + E EE +R ++E++Q E++
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2580
Query: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
R+QEE + + +++REQ + + Q E++
Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEV 2615
Score = 147 bits (370), Expect = 5e-35
Identities = 149/681 (21%), Positives = 321/681 (47%), Gaps = 72/681 (10%)
Query: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLN-----VKELKRKLER 219
+KE+ L R EE +++ AE + + LA E++ Q V+ LK K+E
Sbjct: 1961 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2020
Query: 220 AKFLLPQVQTNTLQEEMWRQE---EELREQEKK----IRKQEEKMWRQEERLREQEGKMR 272
A+ L + + + ++ QE + L+ +EK ++++E+++ + ++ + ++R
Sbjct: 2021 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2080
Query: 273 EQEEKMRRQEKRLREQ----EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR- 327
+ E RR + E E+E + +++ E ++L++ E+ + + EK+R
Sbjct: 2081 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2140
Query: 328 --EQEEKMWRQEERLWEQEKQMREQE----QKMRDQEERMWEQDER----LREKEERMRE 377
EQE Q E+ ++KQ + E +K +Q R Q E+ LR + E
Sbjct: 2141 EAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH 2200
Query: 378 QEKMWEQEEKMQEEERIREREKKMREEEE--TMREQEEKMQKQEENMWEQE------EKE 429
Q+ + ++E + + E ++ + EEE ++R Q E++ K + + + +K+
Sbjct: 2201 QKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKD 2260
Query: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQM 488
Q+ L E+ EK+ + + + ++ ++R EE Q++ + EKM +++ Q
Sbjct: 2261 NTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL--AEKMLKEKMQA 2318
Query: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK-------KMWQQEEKMREEKK 541
++ +++ + + + Q+E EQ RL+E +E+M +Q + + E+ R+ +
Sbjct: 2319 VQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEM 2378
Query: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ--------EEK------MQEQE 587
+ E E+ E R + R E ++ R++ E + E+ +EK ++ Q
Sbjct: 2379 SAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2438
Query: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE---Q 644
++ E++ E +++ ++EK+ +QE K+ + + E+ Q+E + ++ + +Q+
Sbjct: 2439 QQSDHDAERLREAIAELEREKEKL-QQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLS 2497
Query: 645 EEKMWEQEEKMREQEEKMREQ------EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
E+ Q E+ EQE+ EQ + Q +EE+ R+Q++ Q ++ + EE R
Sbjct: 2498 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2557
Query: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758
Q E G K QEE +++ R++EE + ++ ++++E+L EE+ +
Sbjct: 2558 RQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Query: 759 VLCNMSHTGSVEPAGGEAGEG 779
V + P G +A +G
Sbjct: 2615 VTASQVAATKTLPNGRDALDG 2635
Score = 132 bits (333), Expect = 1e-30
Identities = 143/685 (20%), Positives = 315/685 (45%), Gaps = 60/685 (8%)
Query: 112 QDAARKFEDGN---LGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKER 168
QDA R+ E L +S+ + +L E++R V + A +YI +
Sbjct: 1224 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1283
Query: 169 DALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER-AKFLLPQV 227
L L Y+ + K ++Q E +++ + EL + KF+ +
Sbjct: 1284 --LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETL 1341
Query: 228 QTNTLQEEMWRQE-----EELREQEKKIRKQEE--KMWRQEERLREQEGK---MREQEEK 277
+ +E + Q+ E L E E + KQ + + Q + E+E K R QEE
Sbjct: 1342 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1401
Query: 278 MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
+RR+E + Q+++ R ++EL++ ++ E E Q + ++ + E+ E+E ++ R +
Sbjct: 1402 VRREEAAVDAQQQK-RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1460
Query: 338 ERLWEQEKQMREQE-QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
E+++ E E Q +R + E Q + +E+ ER+R Q Q+E ++ + E
Sbjct: 1461 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV----QDESQRKRQAEVE 1516
Query: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
+++ E E RE++ +Q EE + EE E + ++ ++ + + Q
Sbjct: 1517 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1576
Query: 457 EQEEKIRDQEEMWGQEKKMWRQE-----KMREQEDQMWEQE---EKMRDQEQKMWDQEER 508
E + K E Q ++ ++E ++RE+ ++ +Q+ E+ R++ ++ ++ +
Sbjct: 1577 ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQL 1636
Query: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
+ RLR + E + +QK + Q E + ++E+ +E ++ +E+ +R+ E + +K
Sbjct: 1637 KANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1696
Query: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
R+ E +Q +++ ++R + E+ EQ+ ++ E+E ++E Q
Sbjct: 1697 QRQLAEGTAQQRLAAEQELIRLRAETEQ--------GEQQRQLLEEELARLQREAAAATQ 1748
Query: 629 EQEEMMWEQEEKMQEQEEKMWEQ---EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
+++E+ E + E E + + EE+ R EK +++ E G+ ++ E+ +++
Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1808
Query: 686 QEEKMREQEE-------KMRGQEEKMWGQEEKMWGQEEKMWGQEE--MREKE---ERIRD 733
E+ + Q + + R + E++ ++ G+ ++ + E ++EKE ER+R
Sbjct: 1809 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1868
Query: 734 -------QKEKMQERLPEHEERCSE 751
Q+ +++E+ +H+ E
Sbjct: 1869 LAEDEAFQRRRLEEQAAQHKADIEE 1893
Score = 122 bits (305), Expect = 2e-27
Identities = 136/630 (21%), Positives = 281/630 (44%), Gaps = 58/630 (9%)
Query: 150 VSTWHKKADRYIEELTK----ERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSE 205
+ W + A R E++ + A+ +L + EE+++ +++E R A+ +
Sbjct: 1219 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1278
Query: 206 IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR-QEERL 264
I K+ + +L K L V + + ++ E + ++ +R ++ + +
Sbjct: 1279 I----KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYI 1334
Query: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE 324
+ +R EE+ R E++ E+ + L E E L +Q++L E Q + Q E+ E +E
Sbjct: 1335 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER--EAKE 1392
Query: 325 KMREQEEKMWRQEERLWEQEKQMR---EQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
+ +E++ R+EE + ++Q R E+ Q++R E + R E ER R
Sbjct: 1393 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR----- 1447
Query: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
++ EE IR ++ E E ++Q EE E Q+++ E+ E+
Sbjct: 1448 ------LRIEEEIRVVRLQLEATERQRGGAEGELQALRARA---EEAEAQKRQAQEEAER 1498
Query: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
L Q + + Q ++ E E R + E +K + + E Q E E ++R E +
Sbjct: 1499 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVE 1558
Query: 502 MWDQEERMWEQDERLREKE---------ERMREQKKMWQQEE----KMREE--KKTQEQE 546
Q + E +R E E E+ + ++ Q+E ++REE ++ Q+Q
Sbjct: 1559 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1618
Query: 547 KKTWDQEEKMREEERMREREK---KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
+ +EE RE ER + + ++R + E + +Q+ Q + EK +E+ E+ + K
Sbjct: 1619 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1678
Query: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
+EQ + E E +E +K ++ E +Q +++ ++ + E+ +Q + +
Sbjct: 1679 AEEQAVRQRELAE-----QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1733
Query: 664 EQEEKMQGQEEKMREQEEKMQGQEEKMREQEE-----KMRGQEEKMWGQEEKMWGQEEKM 718
E+ ++Q + ++ ++++ + K+R + E K R +EE E+ E +
Sbjct: 1734 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEA 1793
Query: 719 WGQEEMREKEERIR--DQKEKMQERLPEHE 746
E+ E+ R+R ++ K Q +L E +
Sbjct: 1794 GRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Score = 117 bits (293), Expect = 4e-26
Identities = 155/750 (20%), Positives = 337/750 (44%), Gaps = 95/750 (12%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
E+E+ A Q E R E + L Q+ E A R E+K+L
Sbjct: 1346 EEERLAEQQRAEERERLAEVE----AALEKQRQLAEAHAQAKAQAER--------EAKEL 1393
Query: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
R+ ++R +AV +K EEL + R + E+ E ++
Sbjct: 1394 QQRMQEE-----VVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSR 1447
Query: 190 AELQEKLRLA--ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247
++E++R+ + E +E Q E + + RA+ + Q QEE R +++++
Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1507
Query: 248 KKIRKQE----EKMWRQEERLREQEGKMREQEE---KMRRQEKRLREQEKELREQEKELR 300
++ R+ E ++ + E RE++ ++ EE + E+RLR+ E E R ++ ++
Sbjct: 1508 QRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVE-RARQVQVA 1566
Query: 301 EQKKLREQEEQMQEQE----EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
+ R E ++Q + EK + E ++E+ + + E E+ Q + + ++ R+
Sbjct: 1567 LETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA-ERRAQQQAEAERARE 1625
Query: 357 QEERMWEQDE-------RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
+ ER E+ + RLR + E + +Q+ + + E + Q+EE RE ++ + EE+ +R
Sbjct: 1626 EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVR 1685
Query: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEE 467
++E + +QE Q + QQRL ++E +L + + EQ+ ++ E+E +E
Sbjct: 1686 QRE--LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA 1743
Query: 468 MWGQEKKMWRQEKMREQEDQMW---------EQEEKMRDQEQKMWDQEE-----RMWEQD 513
+K+ + ++ + +M E+E + ++ K + E + E+
Sbjct: 1744 AAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEA 1803
Query: 514 ERLREKEERMREQKKMWQQEE-KMREEKKTQEQEK----------KTWDQ---EEKMREE 559
RLR E + Q+++ +++ + R E + EK KT + +EK E
Sbjct: 1804 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1863
Query: 560 ERMR----EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
ER+R + + R EE + + ++E+ ++R+ + E+++ + E + Q
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1923
Query: 616 EK-------MWEQEEEDKMQEQEEM---MWEQEEKMQEQEEKMWE---QEEKMREQEEKM 662
E+ +E+ K + + E+ E+ ++ +E+ E Q + E+E +
Sbjct: 1924 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1983
Query: 663 REQEEKMQ----GQEEKMREQEEKMQGQEEKMREQEE--KMRGQEEKMWGQEEKMWGQEE 716
RE EE++Q +EE R+++ ++ E + EE ++R + E+ ++ ++ +
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043
Query: 717 KMWGQEEMREKEERIRDQKEKMQERLPEHE 746
+ Q E + ++ +++++Q+ L + +
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQ 2073
Score = 115 bits (288), Expect = 2e-25
Identities = 173/821 (21%), Positives = 342/821 (41%), Gaps = 149/821 (18%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESK-- 127
E+E + EA R+ + ++ L + E E +Q+ A + ES+
Sbjct: 1451 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRK 1510
Query: 128 -----DLAGRLHHSWHFAGELQRALSAVSTWH---KKADRYIEELTKERDA---LSLELY 176
+LA R+ A E QRAL A+ ++A+R + + ER ++LE
Sbjct: 1511 RQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1570
Query: 177 RNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 236
+ + EL+ K A EK E E + V +L+ + ER Q + +EE
Sbjct: 1571 QRS-AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA--QQQAEAERAREEA 1627
Query: 237 WR-----------------QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279
R Q EE+ +Q+ + + EK + ER + GK EQ + R
Sbjct: 1628 ERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR 1687
Query: 280 RQEKRLREQEKELRE---QEKELREQKKLR--------EQEEQMQEQEEKMWEQEE---- 324
++ E++++L E Q++ EQ+ +R EQ+ Q+ E+E ++E
Sbjct: 1688 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1747
Query: 325 -----------KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE----ERMWEQDERLR 369
K+R + E + + R E+ + E+ ++ + E + E+ RLR
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807
Query: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK----MQKQEENMWEQ 425
E + Q ++ E++ Q E R +K+ E R + E +K+ EN +
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1867
Query: 426 ---EEKEWQQQRLPEQ--------KEKLWEQEKMQEQE-------------EKIWEQEE- 460
E++ +Q++RL EQ +E+L + K + E ++ +EE
Sbjct: 1868 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1927
Query: 461 ----------------------KIRDQEEMWGQEKKMWRQEKMR------EQEDQMWEQE 492
+IR E + K+ E R E+E + E E
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 493 EKMRDQ---EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
E+++ E++ Q + E+ ERL+ K E R ++ +QE R+ + QE +K
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA-RQLQLAQEAAQKR 2046
Query: 550 WDQEEKMRE---EERMREREKKMREEEEMM-------------REQEEKMQEQEEKMREQ 593
EEK +++ +E ++ +++E+ ++ E+ E+ + Q E+ Q
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 594 EEKMWEQEEKM-QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
+ E+ E++ Q EE+ + + E+ K EQE Q E+ ++++ + E
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2166
Query: 653 -EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
EK ++ E+ Q+ +++ + +R Q E+ Q+ + E+ ++++ + + Q ++
Sbjct: 2167 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2226
Query: 712 WGQEEKMWG----QEEMREKEERIRDQKEKMQERLPEHEER 748
EE+++ EE+ + + RI + + R ++ +R
Sbjct: 2227 ---EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2264
Score = 115 bits (287), Expect = 2e-25
Identities = 139/624 (22%), Positives = 276/624 (44%), Gaps = 57/624 (9%)
Query: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
EE KE A+ L T LKK A+ AE+++ EL+ E +
Sbjct: 1109 EEQLKEAQAVPATLPELEATKASLKKLRAQ-------AEAQQPTFDALRDELRGAQEVGE 1161
Query: 222 FLLPQVQTNTLQEEMWRQE-EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
L + ++ E WR+ +L E+ + + Q + R+ E+L Q RE + +
Sbjct: 1162 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1221
Query: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
+ R +++++ Q L + + +REQ Q Q E++ EK+ E + + +
Sbjct: 1222 WLQDARRRQEQI--QAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAI 1279
Query: 341 WEQEKQM------------REQEQKMRDQEERMWEQDERLREKEERMREQEKMW-----E 383
+ E Q+ ++ K++ E + ++ LR + + E
Sbjct: 1280 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1339
Query: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE---------NMWEQEEKEWQQQR 434
+M+EEER+ E+++ EE E + E E ++KQ + E+E KE QQ+
Sbjct: 1340 TLRRMEEEERLAEQQRA--EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRM 1397
Query: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
E + Q+Q+ I E+ +++R E Q K RQ + E+ E+E +
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA--RQAEAAERSRLRIEEEIR 1455
Query: 495 MRDQEQKMWDQEERMWEQD-ERLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTWDQ 552
+ + + +++ E + + LR + E QK+ Q+E E++R + + + Q K+ +
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1515
Query: 553 EEKMR---EEERMREREKKMREEEEMMREQEE---KMQEQEEKMREQEEKMWEQEEKMQE 606
E R E E RE+++ ++ EE+ + EE ++++ E + Q + E ++ E
Sbjct: 1516 ELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAE 1575
Query: 607 QEEKMWEQEEKMWEQEEEDKMQEQE----EMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
E + + E +QE+ ++ E E + Q+Q E +EE RE E
Sbjct: 1576 AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQ 1635
Query: 663 REQEE--KMQGQEEKMREQEEKMQGQEEKMREQ---EEKMRGQEEKMWGQEEKMWGQEEK 717
+ E +++ Q E++ +Q+ Q + EK +E+ E + RG+ E+ ++ ++ QE +
Sbjct: 1636 LKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1695
Query: 718 MWGQEEMREKEERIRDQKEKMQER 741
Q ++R+ ++E ++ R
Sbjct: 1696 KQRQLAEGTAQQRLAAEQELIRLR 1719
Score = 107 bits (266), Expect = 6e-23
Identities = 152/689 (22%), Positives = 290/689 (42%), Gaps = 118/689 (17%)
Query: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
+KA +E L K LS E +K L E A + +SE++L + +L+
Sbjct: 1027 QKAQAEVEGLGKGVARLSAEA-----------EKVLALPEPSPAAPTLRSELELTLGKLE 1075
Query: 215 RKLERAKFLLPQVQTNTL--------QEEMWRQEEELREQE----------------KKI 250
+ + L +++T +L +E + EE+L+E + KK+
Sbjct: 1076 QVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKL 1135
Query: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ-KKLREQE 309
R Q E + LR++ +E E+++++ + + RE+ +L E+ + + Q
Sbjct: 1136 RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQT 1195
Query: 310 EQMQEQEEKMWEQEEKMREQEEKM--WRQEERLWEQEKQMR--EQEQKMRD---QEERMW 362
+ Q + E++ Q RE + + W Q+ R +++ Q Q +R+ QE+ +
Sbjct: 1196 DVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL 1255
Query: 363 EQDERLREKEERMREQEKMWEQEEKMQE---------EERIREREKKMR----------- 402
E+ ER EK E + K + K E E + KK +
Sbjct: 1256 EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQE 1315
Query: 403 --------EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
E T+ Q K + E+EE+ +QQR E++E+L E E E++ +
Sbjct: 1316 YVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQR-AEERERLAEVEAALEKQRQ 1374
Query: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKM----------REQEDQMWEQEEKMRDQEQKMWD 504
+ E + + Q E +E + QE++ ++Q+ + E+ +++R +
Sbjct: 1375 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1434
Query: 505 QEERMWEQDERLREK-EERMREQKKMWQQEEKMR------------EEKKTQEQEKKTWD 551
+ R E ER R + EE +R + + E+ R ++ + Q+++ +
Sbjct: 1435 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1494
Query: 552 QEEKMR-----EEERMRERE----KKMREEEEMMREQEEKMQEQEE---KMREQEEKMWE 599
+ E++R E +R R+ E +++ E E RE++ +Q EE + E E ++ +
Sbjct: 1495 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1554
Query: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
E + Q + E ++ E E + K E + E +QE+ + + E E E
Sbjct: 1555 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLRE---EAE 1611
Query: 660 EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW 719
+ ++Q E + +EE RE E E +R +R Q E++ Q+ + EK
Sbjct: 1612 RRAQQQAEAERAREEAERELERWQLKANEALR-----LRLQAEEVAQQKSLAQAEAEK-- 1664
Query: 720 GQEEMREKEERIRDQKEKMQERLPEHEER 748
Q+E E+E R R + E+ R E E+
Sbjct: 1665 -QKEEAEREARRRGKAEEQAVRQRELAEQ 1692
Score = 94.4 bits (233), Expect = 4e-19
Identities = 110/477 (23%), Positives = 217/477 (45%), Gaps = 63/477 (13%)
Query: 72 EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG 131
+K Q LR ++E DH +L EL+ + +AAR+
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLD---EELQRLKAEATEAARQ-------------- 2222
Query: 132 RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNT--ITNEELKKKN 189
+++ L +V ++ + + E AL L NT EE +K
Sbjct: 2223 --------RSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK 2274
Query: 190 AELQEKLRL--AESEKSEI-QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
+E RL A E + + QL ++L ++ A+ +L + + + E EL +Q
Sbjct: 2275 QVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQ 2334
Query: 247 EKKI------RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
+K++ R QE+K ++ E +G R E + +RQ + E E+ + R
Sbjct: 2335 QKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSR 2394
Query: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Q + E ++ ++Q E E EK+ R E L QEK Q +++ Q+
Sbjct: 2395 AQARAEEDAQRFRKQAE----------EIGEKLHRTE--LATQEKVTLVQTLEIQRQQSD 2442
Query: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE--EKMQKQ 418
ERLRE + E+EK EK+Q+E ++ + + EE +T+++++ ++ Q
Sbjct: 2443 --HDAERLREAIAEL-EREK-----EKLQQEAKLLQLKS---EEMQTVQQEQLLQETQAL 2491
Query: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
+++ +++ Q++R EQ++ EQ E + +EE+ R Q++M ++++
Sbjct: 2492 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--EQERQRLV 2549
Query: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK 535
M E + E EE +R +++++ E++ +Q+E L E+ +R+REQ ++ +++ +
Sbjct: 2550 ASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2606
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 155 bits (391), Expect = 2e-37
Identities = 158/695 (22%), Positives = 330/695 (47%), Gaps = 67/695 (9%)
Query: 74 KASHQHQEALRREIEAQDHTIR------ILTCQKTELETALY--YSQDAARKFEDGNLGE 125
KAS + A + E+E + IR + + ++ ELE A + + R+ +
Sbjct: 1935 KASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERV 1994
Query: 126 SKDLAGRLHHSWHFAGELQRALSAVSTWHKKAD--RYIEELTKERDALSLELYRNT---- 179
K LA A + + AL V K + R + E ++ A L+L +
Sbjct: 1995 QKSLAAEEEA----ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2050
Query: 180 ITNEE------LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233
+ EE +++K ELQ+ L+ +S +++ + +R E A+ Q + Q
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2110
Query: 234 -----EEMWRQEEELREQEK----------KIRKQEEKMWRQEERLREQEGKMREQEEKM 278
EE R ++ EQ + K+RK+ E+ R + ++ +R+++
Sbjct: 2111 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ--EAARRAQAEQAALRQKQAAD 2168
Query: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
EK + E+ LR++ + +E LR Q E+ Q+ + E+ ++++ + + RQ
Sbjct: 2169 AEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRS 2228
Query: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398
++ E+ +R Q +++ + R+ E + R ++ Q + E+ EKM++ R
Sbjct: 2229 QVEEELFSVRVQMEELSKLKARI-EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARL 2287
Query: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ-----RLPEQKEKLWEQEKM-QEQE 452
+E +R+ E+ Q+ + E+ KE Q RL + E L +Q+++ QEQ
Sbjct: 2288 SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQA 2347
Query: 453 EKIWEQEEKIRDQ--EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
++ E +E++ Q EE G ++ + E R+++ +M + E+++ + +M + R
Sbjct: 2348 RRLQEDKEQMAQQLAEETQGFQRTL---EAERQRQLEMSAEAERLKLRVAEMSRAQARAE 2404
Query: 511 EQDERLREKEERMREQKKMWQ--QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK- 567
E +R R++ E + E+ + +EK+ + + Q +++ E++RE EREK
Sbjct: 2405 EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2464
Query: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ----EEKMQEQEEKMWEQEEKMWEQEE 623
K+++E ++++ + E+MQ +++ QE + +Q E+ Q E+ EQE+ EQ
Sbjct: 2465 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2524
Query: 624 EDKMQEQEEMMWEQEEKMQEQEEK-------MWEQEEKMREQEEKMREQEEKMQGQEEKM 676
+D++ + +++ EQ+ + Q+ E++ M E + E EE +R ++E++Q E++
Sbjct: 2525 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2584
Query: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
R+QEE + + +++REQ + + Q E++
Sbjct: 2585 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEV 2619
Score = 147 bits (370), Expect = 5e-35
Identities = 149/681 (21%), Positives = 321/681 (47%), Gaps = 72/681 (10%)
Query: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLN-----VKELKRKLER 219
+KE+ L R EE +++ AE + + LA E++ Q V+ LK K+E
Sbjct: 1965 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2024
Query: 220 AKFLLPQVQTNTLQEEMWRQE---EELREQEKK----IRKQEEKMWRQEERLREQEGKMR 272
A+ L + + + ++ QE + L+ +EK ++++E+++ + ++ + ++R
Sbjct: 2025 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2084
Query: 273 EQEEKMRRQEKRLREQ----EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR- 327
+ E RR + E E+E + +++ E ++L++ E+ + + EK+R
Sbjct: 2085 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2144
Query: 328 --EQEEKMWRQEERLWEQEKQMREQE----QKMRDQEERMWEQDER----LREKEERMRE 377
EQE Q E+ ++KQ + E +K +Q R Q E+ LR + E
Sbjct: 2145 EAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH 2204
Query: 378 QEKMWEQEEKMQEEERIREREKKMREEEE--TMREQEEKMQKQEENMWEQE------EKE 429
Q+ + ++E + + E ++ + EEE ++R Q E++ K + + + +K+
Sbjct: 2205 QKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKD 2264
Query: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQM 488
Q+ L E+ EK+ + + + ++ ++R EE Q++ + EKM +++ Q
Sbjct: 2265 NTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL--AEKMLKEKMQA 2322
Query: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK-------KMWQQEEKMREEKK 541
++ +++ + + + Q+E EQ RL+E +E+M +Q + + E+ R+ +
Sbjct: 2323 VQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEM 2382
Query: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ--------EEK------MQEQE 587
+ E E+ E R + R E ++ R++ E + E+ +EK ++ Q
Sbjct: 2383 SAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2442
Query: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE---Q 644
++ E++ E +++ ++EK+ +QE K+ + + E+ Q+E + ++ + +Q+
Sbjct: 2443 QQSDHDAERLREAIAELEREKEKL-QQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLS 2501
Query: 645 EEKMWEQEEKMREQEEKMREQ------EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
E+ Q E+ EQE+ EQ + Q +EE+ R+Q++ Q ++ + EE R
Sbjct: 2502 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2561
Query: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758
Q E G K QEE +++ R++EE + ++ ++++E+L EE+ +
Sbjct: 2562 RQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2618
Query: 759 VLCNMSHTGSVEPAGGEAGEG 779
V + P G +A +G
Sbjct: 2619 VTASQVAATKTLPNGRDALDG 2639
Score = 132 bits (333), Expect = 1e-30
Identities = 143/685 (20%), Positives = 315/685 (45%), Gaps = 60/685 (8%)
Query: 112 QDAARKFEDGN---LGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKER 168
QDA R+ E L +S+ + +L E++R V + A +YI +
Sbjct: 1228 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1287
Query: 169 DALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER-AKFLLPQV 227
L L Y+ + K ++Q E +++ + EL + KF+ +
Sbjct: 1288 --LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETL 1345
Query: 228 QTNTLQEEMWRQE-----EELREQEKKIRKQEE--KMWRQEERLREQEGK---MREQEEK 277
+ +E + Q+ E L E E + KQ + + Q + E+E K R QEE
Sbjct: 1346 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1405
Query: 278 MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
+RR+E + Q+++ R ++EL++ ++ E E Q + ++ + E+ E+E ++ R +
Sbjct: 1406 VRREEAAVDAQQQK-RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1464
Query: 338 ERLWEQEKQMREQE-QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
E+++ E E Q +R + E Q + +E+ ER+R Q Q+E ++ + E
Sbjct: 1465 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV----QDESQRKRQAEVE 1520
Query: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
+++ E E RE++ +Q EE + EE E + ++ ++ + + Q
Sbjct: 1521 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1580
Query: 457 EQEEKIRDQEEMWGQEKKMWRQE-----KMREQEDQMWEQE---EKMRDQEQKMWDQEER 508
E + K E Q ++ ++E ++RE+ ++ +Q+ E+ R++ ++ ++ +
Sbjct: 1581 ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQL 1640
Query: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
+ RLR + E + +QK + Q E + ++E+ +E ++ +E+ +R+ E + +K
Sbjct: 1641 KANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1700
Query: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
R+ E +Q +++ ++R + E+ EQ+ ++ E+E ++E Q
Sbjct: 1701 QRQLAEGTAQQRLAAEQELIRLRAETEQ--------GEQQRQLLEEELARLQREAAAATQ 1752
Query: 629 EQEEMMWEQEEKMQEQEEKMWEQ---EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
+++E+ E + E E + + EE+ R EK +++ E G+ ++ E+ +++
Sbjct: 1753 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1812
Query: 686 QEEKMREQEE-------KMRGQEEKMWGQEEKMWGQEEKMWGQEE--MREKE---ERIRD 733
E+ + Q + + R + E++ ++ G+ ++ + E ++EKE ER+R
Sbjct: 1813 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1872
Query: 734 -------QKEKMQERLPEHEERCSE 751
Q+ +++E+ +H+ E
Sbjct: 1873 LAEDEAFQRRRLEEQAAQHKADIEE 1897
Score = 122 bits (305), Expect = 2e-27
Identities = 136/630 (21%), Positives = 281/630 (44%), Gaps = 58/630 (9%)
Query: 150 VSTWHKKADRYIEELTK----ERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSE 205
+ W + A R E++ + A+ +L + EE+++ +++E R A+ +
Sbjct: 1223 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1282
Query: 206 IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR-QEERL 264
I K+ + +L K L V + + ++ E + ++ +R ++ + +
Sbjct: 1283 I----KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYI 1338
Query: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE 324
+ +R EE+ R E++ E+ + L E E L +Q++L E Q + Q E+ E +E
Sbjct: 1339 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER--EAKE 1396
Query: 325 KMREQEEKMWRQEERLWEQEKQMR---EQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
+ +E++ R+EE + ++Q R E+ Q++R E + R E ER R
Sbjct: 1397 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR----- 1451
Query: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
++ EE IR ++ E E ++Q EE E Q+++ E+ E+
Sbjct: 1452 ------LRIEEEIRVVRLQLEATERQRGGAEGELQALRARA---EEAEAQKRQAQEEAER 1502
Query: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
L Q + + Q ++ E E R + E +K + + E Q E E ++R E +
Sbjct: 1503 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVE 1562
Query: 502 MWDQEERMWEQDERLREKE---------ERMREQKKMWQQEE----KMREE--KKTQEQE 546
Q + E +R E E E+ + ++ Q+E ++REE ++ Q+Q
Sbjct: 1563 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1622
Query: 547 KKTWDQEEKMREEERMREREK---KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
+ +EE RE ER + + ++R + E + +Q+ Q + EK +E+ E+ + K
Sbjct: 1623 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1682
Query: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
+EQ + E E +E +K ++ E +Q +++ ++ + E+ +Q + +
Sbjct: 1683 AEEQAVRQRELAE-----QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1737
Query: 664 EQEEKMQGQEEKMREQEEKMQGQEEKMREQEE-----KMRGQEEKMWGQEEKMWGQEEKM 718
E+ ++Q + ++ ++++ + K+R + E K R +EE E+ E +
Sbjct: 1738 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEA 1797
Query: 719 WGQEEMREKEERIR--DQKEKMQERLPEHE 746
E+ E+ R+R ++ K Q +L E +
Sbjct: 1798 GRFRELAEEAARLRALAEEAKRQRQLAEED 1827
Score = 117 bits (293), Expect = 4e-26
Identities = 155/750 (20%), Positives = 337/750 (44%), Gaps = 95/750 (12%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
E+E+ A Q E R E + L Q+ E A R E+K+L
Sbjct: 1350 EEERLAEQQRAEERERLAEVE----AALEKQRQLAEAHAQAKAQAER--------EAKEL 1397
Query: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
R+ ++R +AV +K EEL + R + E+ E ++
Sbjct: 1398 QQRMQEE-----VVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSR 1451
Query: 190 AELQEKLRLA--ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247
++E++R+ + E +E Q E + + RA+ + Q QEE R +++++
Sbjct: 1452 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1511
Query: 248 KKIRKQE----EKMWRQEERLREQEGKMREQEE---KMRRQEKRLREQEKELREQEKELR 300
++ R+ E ++ + E RE++ ++ EE + E+RLR+ E E R ++ ++
Sbjct: 1512 QRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVE-RARQVQVA 1570
Query: 301 EQKKLREQEEQMQEQE----EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
+ R E ++Q + EK + E ++E+ + + E E+ Q + + ++ R+
Sbjct: 1571 LETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA-ERRAQQQAEAERARE 1629
Query: 357 QEERMWEQDE-------RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
+ ER E+ + RLR + E + +Q+ + + E + Q+EE RE ++ + EE+ +R
Sbjct: 1630 EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVR 1689
Query: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEE 467
++E + +QE Q + QQRL ++E +L + + EQ+ ++ E+E +E
Sbjct: 1690 QRE--LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA 1747
Query: 468 MWGQEKKMWRQEKMREQEDQMW---------EQEEKMRDQEQKMWDQEE-----RMWEQD 513
+K+ + ++ + +M E+E + ++ K + E + E+
Sbjct: 1748 AAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEA 1807
Query: 514 ERLREKEERMREQKKMWQQEE-KMREEKKTQEQEK----------KTWDQ---EEKMREE 559
RLR E + Q+++ +++ + R E + EK KT + +EK E
Sbjct: 1808 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1867
Query: 560 ERMR----EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
ER+R + + R EE + + ++E+ ++R+ + E+++ + E + Q
Sbjct: 1868 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1927
Query: 616 EK-------MWEQEEEDKMQEQEEM---MWEQEEKMQEQEEKMWE---QEEKMREQEEKM 662
E+ +E+ K + + E+ E+ ++ +E+ E Q + E+E +
Sbjct: 1928 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1987
Query: 663 REQEEKMQ----GQEEKMREQEEKMQGQEEKMREQEE--KMRGQEEKMWGQEEKMWGQEE 716
RE EE++Q +EE R+++ ++ E + EE ++R + E+ ++ ++ +
Sbjct: 1988 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2047
Query: 717 KMWGQEEMREKEERIRDQKEKMQERLPEHE 746
+ Q E + ++ +++++Q+ L + +
Sbjct: 2048 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQ 2077
Score = 115 bits (288), Expect = 2e-25
Identities = 173/821 (21%), Positives = 342/821 (41%), Gaps = 149/821 (18%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESK-- 127
E+E + EA R+ + ++ L + E E +Q+ A + ES+
Sbjct: 1455 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRK 1514
Query: 128 -----DLAGRLHHSWHFAGELQRALSAVSTWH---KKADRYIEELTKERDA---LSLELY 176
+LA R+ A E QRAL A+ ++A+R + + ER ++LE
Sbjct: 1515 RQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1574
Query: 177 RNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 236
+ + EL+ K A EK E E + V +L+ + ER Q + +EE
Sbjct: 1575 QRS-AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA--QQQAEAERAREEA 1631
Query: 237 WR-----------------QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279
R Q EE+ +Q+ + + EK + ER + GK EQ + R
Sbjct: 1632 ERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR 1691
Query: 280 RQEKRLREQEKELRE---QEKELREQKKLR--------EQEEQMQEQEEKMWEQEE---- 324
++ E++++L E Q++ EQ+ +R EQ+ Q+ E+E ++E
Sbjct: 1692 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1751
Query: 325 -----------KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE----ERMWEQDERLR 369
K+R + E + + R E+ + E+ ++ + E + E+ RLR
Sbjct: 1752 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1811
Query: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK----MQKQEENMWEQ 425
E + Q ++ E++ Q E R +K+ E R + E +K+ EN +
Sbjct: 1812 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1871
Query: 426 ---EEKEWQQQRLPEQ--------KEKLWEQEKMQEQE-------------EKIWEQEE- 460
E++ +Q++RL EQ +E+L + K + E ++ +EE
Sbjct: 1872 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1931
Query: 461 ----------------------KIRDQEEMWGQEKKMWRQEKMR------EQEDQMWEQE 492
+IR E + K+ E R E+E + E E
Sbjct: 1932 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1991
Query: 493 EKMRDQ---EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
E+++ E++ Q + E+ ERL+ K E R ++ +QE R+ + QE +K
Sbjct: 1992 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA-RQLQLAQEAAQKR 2050
Query: 550 WDQEEKMRE---EERMREREKKMREEEEMM-------------REQEEKMQEQEEKMREQ 593
EEK +++ +E ++ +++E+ ++ E+ E+ + Q E+ Q
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2110
Query: 594 EEKMWEQEEKM-QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
+ E+ E++ Q EE+ + + E+ K EQE Q E+ ++++ + E
Sbjct: 2111 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2170
Query: 653 -EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
EK ++ E+ Q+ +++ + +R Q E+ Q+ + E+ ++++ + + Q ++
Sbjct: 2171 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2230
Query: 712 WGQEEKMWG----QEEMREKEERIRDQKEKMQERLPEHEER 748
EE+++ EE+ + + RI + + R ++ +R
Sbjct: 2231 ---EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2268
Score = 115 bits (287), Expect = 2e-25
Identities = 139/624 (22%), Positives = 276/624 (44%), Gaps = 57/624 (9%)
Query: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
EE KE A+ L T LKK A+ AE+++ EL+ E +
Sbjct: 1113 EEQLKEAQAVPATLPELEATKASLKKLRAQ-------AEAQQPTFDALRDELRGAQEVGE 1165
Query: 222 FLLPQVQTNTLQEEMWRQE-EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
L + ++ E WR+ +L E+ + + Q + R+ E+L Q RE + +
Sbjct: 1166 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1225
Query: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
+ R +++++ Q L + + +REQ Q Q E++ EK+ E + + +
Sbjct: 1226 WLQDARRRQEQI--QAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAI 1283
Query: 341 WEQEKQM------------REQEQKMRDQEERMWEQDERLREKEERMREQEKMW-----E 383
+ E Q+ ++ K++ E + ++ LR + + E
Sbjct: 1284 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1343
Query: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE---------NMWEQEEKEWQQQR 434
+M+EEER+ E+++ EE E + E E ++KQ + E+E KE QQ+
Sbjct: 1344 TLRRMEEEERLAEQQRA--EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRM 1401
Query: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
E + Q+Q+ I E+ +++R E Q K RQ + E+ E+E +
Sbjct: 1402 QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA--RQAEAAERSRLRIEEEIR 1459
Query: 495 MRDQEQKMWDQEERMWEQD-ERLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTWDQ 552
+ + + +++ E + + LR + E QK+ Q+E E++R + + + Q K+ +
Sbjct: 1460 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1519
Query: 553 EEKMR---EEERMREREKKMREEEEMMREQEE---KMQEQEEKMREQEEKMWEQEEKMQE 606
E R E E RE+++ ++ EE+ + EE ++++ E + Q + E ++ E
Sbjct: 1520 ELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAE 1579
Query: 607 QEEKMWEQEEKMWEQEEEDKMQEQE----EMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
E + + E +QE+ ++ E E + Q+Q E +EE RE E
Sbjct: 1580 AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQ 1639
Query: 663 REQEE--KMQGQEEKMREQEEKMQGQEEKMREQ---EEKMRGQEEKMWGQEEKMWGQEEK 717
+ E +++ Q E++ +Q+ Q + EK +E+ E + RG+ E+ ++ ++ QE +
Sbjct: 1640 LKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1699
Query: 718 MWGQEEMREKEERIRDQKEKMQER 741
Q ++R+ ++E ++ R
Sbjct: 1700 KQRQLAEGTAQQRLAAEQELIRLR 1723
Score = 107 bits (266), Expect = 6e-23
Identities = 152/689 (22%), Positives = 290/689 (42%), Gaps = 118/689 (17%)
Query: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
+KA +E L K LS E +K L E A + +SE++L + +L+
Sbjct: 1031 QKAQAEVEGLGKGVARLSAEA-----------EKVLALPEPSPAAPTLRSELELTLGKLE 1079
Query: 215 RKLERAKFLLPQVQTNTL--------QEEMWRQEEELREQE----------------KKI 250
+ + L +++T +L +E + EE+L+E + KK+
Sbjct: 1080 QVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKL 1139
Query: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ-KKLREQE 309
R Q E + LR++ +E E+++++ + + RE+ +L E+ + + Q
Sbjct: 1140 RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQT 1199
Query: 310 EQMQEQEEKMWEQEEKMREQEEKM--WRQEERLWEQEKQMR--EQEQKMRD---QEERMW 362
+ Q + E++ Q RE + + W Q+ R +++ Q Q +R+ QE+ +
Sbjct: 1200 DVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL 1259
Query: 363 EQDERLREKEERMREQEKMWEQEEKMQE---------EERIREREKKMR----------- 402
E+ ER EK E + K + K E E + KK +
Sbjct: 1260 EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQE 1319
Query: 403 --------EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
E T+ Q K + E+EE+ +QQR E++E+L E E E++ +
Sbjct: 1320 YVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQR-AEERERLAEVEAALEKQRQ 1378
Query: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKM----------REQEDQMWEQEEKMRDQEQKMWD 504
+ E + + Q E +E + QE++ ++Q+ + E+ +++R +
Sbjct: 1379 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1438
Query: 505 QEERMWEQDERLREK-EERMREQKKMWQQEEKMR------------EEKKTQEQEKKTWD 551
+ R E ER R + EE +R + + E+ R ++ + Q+++ +
Sbjct: 1439 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1498
Query: 552 QEEKMR-----EEERMRERE----KKMREEEEMMREQEEKMQEQEE---KMREQEEKMWE 599
+ E++R E +R R+ E +++ E E RE++ +Q EE + E E ++ +
Sbjct: 1499 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1558
Query: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
E + Q + E ++ E E + K E + E +QE+ + + E E E
Sbjct: 1559 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLRE---EAE 1615
Query: 660 EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW 719
+ ++Q E + +EE RE E E +R +R Q E++ Q+ + EK
Sbjct: 1616 RRAQQQAEAERAREEAERELERWQLKANEALR-----LRLQAEEVAQQKSLAQAEAEK-- 1668
Query: 720 GQEEMREKEERIRDQKEKMQERLPEHEER 748
Q+E E+E R R + E+ R E E+
Sbjct: 1669 -QKEEAEREARRRGKAEEQAVRQRELAEQ 1696
Score = 94.4 bits (233), Expect = 4e-19
Identities = 110/477 (23%), Positives = 217/477 (45%), Gaps = 63/477 (13%)
Query: 72 EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG 131
+K Q LR ++E DH +L EL+ + +AAR+
Sbjct: 2184 QKAQVEQELTTLRLQLEETDHQKNLLD---EELQRLKAEATEAARQ-------------- 2226
Query: 132 RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNT--ITNEELKKKN 189
+++ L +V ++ + + E AL L NT EE +K
Sbjct: 2227 --------RSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK 2278
Query: 190 AELQEKLRL--AESEKSEI-QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
+E RL A E + + QL ++L ++ A+ +L + + + E EL +Q
Sbjct: 2279 QVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQ 2338
Query: 247 EKKI------RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
+K++ R QE+K ++ E +G R E + +RQ + E E+ + R
Sbjct: 2339 QKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSR 2398
Query: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Q + E ++ ++Q E E EK+ R E L QEK Q +++ Q+
Sbjct: 2399 AQARAEEDAQRFRKQAE----------EIGEKLHRTE--LATQEKVTLVQTLEIQRQQSD 2446
Query: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE--EKMQKQ 418
ERLRE + E+EK EK+Q+E ++ + + EE +T+++++ ++ Q
Sbjct: 2447 --HDAERLREAIAEL-EREK-----EKLQQEAKLLQLKS---EEMQTVQQEQLLQETQAL 2495
Query: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
+++ +++ Q++R EQ++ EQ E + +EE+ R Q++M ++++
Sbjct: 2496 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--EQERQRLV 2553
Query: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK 535
M E + E EE +R +++++ E++ +Q+E L E+ +R+REQ ++ +++ +
Sbjct: 2554 ASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2610
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 155 bits (391), Expect = 2e-37
Identities = 158/695 (22%), Positives = 330/695 (47%), Gaps = 67/695 (9%)
Query: 74 KASHQHQEALRREIEAQDHTIR------ILTCQKTELETALY--YSQDAARKFEDGNLGE 125
KAS + A + E+E + IR + + ++ ELE A + + R+ +
Sbjct: 1931 KASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERV 1990
Query: 126 SKDLAGRLHHSWHFAGELQRALSAVSTWHKKAD--RYIEELTKERDALSLELYRNT---- 179
K LA A + + AL V K + R + E ++ A L+L +
Sbjct: 1991 QKSLAAEEEA----ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 180 ITNEE------LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233
+ EE +++K ELQ+ L+ +S +++ + +R E A+ Q + Q
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 234 -----EEMWRQEEELREQEK----------KIRKQEEKMWRQEERLREQEGKMREQEEKM 278
EE R ++ EQ + K+RK+ E+ R + ++ +R+++
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ--EAARRAQAEQAALRQKQAAD 2164
Query: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
EK + E+ LR++ + +E LR Q E+ Q+ + E+ ++++ + + RQ
Sbjct: 2165 AEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRS 2224
Query: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398
++ E+ +R Q +++ + R+ E + R ++ Q + E+ EKM++ R
Sbjct: 2225 QVEEELFSVRVQMEELSKLKARI-EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARL 2283
Query: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ-----RLPEQKEKLWEQEKM-QEQE 452
+E +R+ E+ Q+ + E+ KE Q RL + E L +Q+++ QEQ
Sbjct: 2284 SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQA 2343
Query: 453 EKIWEQEEKIRDQ--EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
++ E +E++ Q EE G ++ + E R+++ +M + E+++ + +M + R
Sbjct: 2344 RRLQEDKEQMAQQLAEETQGFQRTL---EAERQRQLEMSAEAERLKLRVAEMSRAQARAE 2400
Query: 511 EQDERLREKEERMREQKKMWQ--QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK- 567
E +R R++ E + E+ + +EK+ + + Q +++ E++RE EREK
Sbjct: 2401 EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2460
Query: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ----EEKMQEQEEKMWEQEEKMWEQEE 623
K+++E ++++ + E+MQ +++ QE + +Q E+ Q E+ EQE+ EQ
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 624 EDKMQEQEEMMWEQEEKMQEQEEK-------MWEQEEKMREQEEKMREQEEKMQGQEEKM 676
+D++ + +++ EQ+ + Q+ E++ M E + E EE +R ++E++Q E++
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2580
Query: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
R+QEE + + +++REQ + + Q E++
Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEV 2615
Score = 147 bits (370), Expect = 5e-35
Identities = 149/681 (21%), Positives = 321/681 (47%), Gaps = 72/681 (10%)
Query: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLN-----VKELKRKLER 219
+KE+ L R EE +++ AE + + LA E++ Q V+ LK K+E
Sbjct: 1961 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2020
Query: 220 AKFLLPQVQTNTLQEEMWRQE---EELREQEKK----IRKQEEKMWRQEERLREQEGKMR 272
A+ L + + + ++ QE + L+ +EK ++++E+++ + ++ + ++R
Sbjct: 2021 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2080
Query: 273 EQEEKMRRQEKRLREQ----EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR- 327
+ E RR + E E+E + +++ E ++L++ E+ + + EK+R
Sbjct: 2081 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2140
Query: 328 --EQEEKMWRQEERLWEQEKQMREQE----QKMRDQEERMWEQDER----LREKEERMRE 377
EQE Q E+ ++KQ + E +K +Q R Q E+ LR + E
Sbjct: 2141 EAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH 2200
Query: 378 QEKMWEQEEKMQEEERIREREKKMREEEE--TMREQEEKMQKQEENMWEQE------EKE 429
Q+ + ++E + + E ++ + EEE ++R Q E++ K + + + +K+
Sbjct: 2201 QKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKD 2260
Query: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQM 488
Q+ L E+ EK+ + + + ++ ++R EE Q++ + EKM +++ Q
Sbjct: 2261 NTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL--AEKMLKEKMQA 2318
Query: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK-------KMWQQEEKMREEKK 541
++ +++ + + + Q+E EQ RL+E +E+M +Q + + E+ R+ +
Sbjct: 2319 VQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEM 2378
Query: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ--------EEK------MQEQE 587
+ E E+ E R + R E ++ R++ E + E+ +EK ++ Q
Sbjct: 2379 SAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR 2438
Query: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE---Q 644
++ E++ E +++ ++EK+ +QE K+ + + E+ Q+E + ++ + +Q+
Sbjct: 2439 QQSDHDAERLREAIAELEREKEKL-QQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLS 2497
Query: 645 EEKMWEQEEKMREQEEKMREQ------EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
E+ Q E+ EQE+ EQ + Q +EE+ R+Q++ Q ++ + EE R
Sbjct: 2498 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2557
Query: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758
Q E G K QEE +++ R++EE + ++ ++++E+L EE+ +
Sbjct: 2558 RQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Query: 759 VLCNMSHTGSVEPAGGEAGEG 779
V + P G +A +G
Sbjct: 2615 VTASQVAATKTLPNGRDALDG 2635
Score = 132 bits (333), Expect = 1e-30
Identities = 143/685 (20%), Positives = 315/685 (45%), Gaps = 60/685 (8%)
Query: 112 QDAARKFEDGN---LGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKER 168
QDA R+ E L +S+ + +L E++R V + A +YI +
Sbjct: 1224 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1283
Query: 169 DALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER-AKFLLPQV 227
L L Y+ + K ++Q E +++ + EL + KF+ +
Sbjct: 1284 --LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETL 1341
Query: 228 QTNTLQEEMWRQE-----EELREQEKKIRKQEE--KMWRQEERLREQEGK---MREQEEK 277
+ +E + Q+ E L E E + KQ + + Q + E+E K R QEE
Sbjct: 1342 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1401
Query: 278 MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
+RR+E + Q+++ R ++EL++ ++ E E Q + ++ + E+ E+E ++ R +
Sbjct: 1402 VRREEAAVDAQQQK-RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1460
Query: 338 ERLWEQEKQMREQE-QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
E+++ E E Q +R + E Q + +E+ ER+R Q Q+E ++ + E
Sbjct: 1461 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV----QDESQRKRQAEVE 1516
Query: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
+++ E E RE++ +Q EE + EE E + ++ ++ + + Q
Sbjct: 1517 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1576
Query: 457 EQEEKIRDQEEMWGQEKKMWRQE-----KMREQEDQMWEQE---EKMRDQEQKMWDQEER 508
E + K E Q ++ ++E ++RE+ ++ +Q+ E+ R++ ++ ++ +
Sbjct: 1577 ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQL 1636
Query: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
+ RLR + E + +QK + Q E + ++E+ +E ++ +E+ +R+ E + +K
Sbjct: 1637 KANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1696
Query: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
R+ E +Q +++ ++R + E+ EQ+ ++ E+E ++E Q
Sbjct: 1697 QRQLAEGTAQQRLAAEQELIRLRAETEQ--------GEQQRQLLEEELARLQREAAAATQ 1748
Query: 629 EQEEMMWEQEEKMQEQEEKMWEQ---EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
+++E+ E + E E + + EE+ R EK +++ E G+ ++ E+ +++
Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1808
Query: 686 QEEKMREQEE-------KMRGQEEKMWGQEEKMWGQEEKMWGQEE--MREKE---ERIRD 733
E+ + Q + + R + E++ ++ G+ ++ + E ++EKE ER+R
Sbjct: 1809 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1868
Query: 734 -------QKEKMQERLPEHEERCSE 751
Q+ +++E+ +H+ E
Sbjct: 1869 LAEDEAFQRRRLEEQAAQHKADIEE 1893
Score = 122 bits (305), Expect = 2e-27
Identities = 136/630 (21%), Positives = 281/630 (44%), Gaps = 58/630 (9%)
Query: 150 VSTWHKKADRYIEELTK----ERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSE 205
+ W + A R E++ + A+ +L + EE+++ +++E R A+ +
Sbjct: 1219 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1278
Query: 206 IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR-QEERL 264
I K+ + +L K L V + + ++ E + ++ +R ++ + +
Sbjct: 1279 I----KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYI 1334
Query: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE 324
+ +R EE+ R E++ E+ + L E E L +Q++L E Q + Q E+ E +E
Sbjct: 1335 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER--EAKE 1392
Query: 325 KMREQEEKMWRQEERLWEQEKQMR---EQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
+ +E++ R+EE + ++Q R E+ Q++R E + R E ER R
Sbjct: 1393 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR----- 1447
Query: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
++ EE IR ++ E E ++Q EE E Q+++ E+ E+
Sbjct: 1448 ------LRIEEEIRVVRLQLEATERQRGGAEGELQALRARA---EEAEAQKRQAQEEAER 1498
Query: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
L Q + + Q ++ E E R + E +K + + E Q E E ++R E +
Sbjct: 1499 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVE 1558
Query: 502 MWDQEERMWEQDERLREKE---------ERMREQKKMWQQEE----KMREE--KKTQEQE 546
Q + E +R E E E+ + ++ Q+E ++REE ++ Q+Q
Sbjct: 1559 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1618
Query: 547 KKTWDQEEKMREEERMREREK---KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
+ +EE RE ER + + ++R + E + +Q+ Q + EK +E+ E+ + K
Sbjct: 1619 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1678
Query: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
+EQ + E E +E +K ++ E +Q +++ ++ + E+ +Q + +
Sbjct: 1679 AEEQAVRQRELAE-----QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1733
Query: 664 EQEEKMQGQEEKMREQEEKMQGQEEKMREQEE-----KMRGQEEKMWGQEEKMWGQEEKM 718
E+ ++Q + ++ ++++ + K+R + E K R +EE E+ E +
Sbjct: 1734 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEA 1793
Query: 719 WGQEEMREKEERIR--DQKEKMQERLPEHE 746
E+ E+ R+R ++ K Q +L E +
Sbjct: 1794 GRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Score = 117 bits (293), Expect = 4e-26
Identities = 155/750 (20%), Positives = 337/750 (44%), Gaps = 95/750 (12%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
E+E+ A Q E R E + L Q+ E A R E+K+L
Sbjct: 1346 EEERLAEQQRAEERERLAEVE----AALEKQRQLAEAHAQAKAQAER--------EAKEL 1393
Query: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
R+ ++R +AV +K EEL + R + E+ E ++
Sbjct: 1394 QQRMQEE-----VVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSR 1447
Query: 190 AELQEKLRLA--ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247
++E++R+ + E +E Q E + + RA+ + Q QEE R +++++
Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1507
Query: 248 KKIRKQE----EKMWRQEERLREQEGKMREQEE---KMRRQEKRLREQEKELREQEKELR 300
++ R+ E ++ + E RE++ ++ EE + E+RLR+ E E R ++ ++
Sbjct: 1508 QRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVE-RARQVQVA 1566
Query: 301 EQKKLREQEEQMQEQE----EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
+ R E ++Q + EK + E ++E+ + + E E+ Q + + ++ R+
Sbjct: 1567 LETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA-ERRAQQQAEAERARE 1625
Query: 357 QEERMWEQDE-------RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
+ ER E+ + RLR + E + +Q+ + + E + Q+EE RE ++ + EE+ +R
Sbjct: 1626 EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVR 1685
Query: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEE 467
++E + +QE Q + QQRL ++E +L + + EQ+ ++ E+E +E
Sbjct: 1686 QRE--LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA 1743
Query: 468 MWGQEKKMWRQEKMREQEDQMW---------EQEEKMRDQEQKMWDQEE-----RMWEQD 513
+K+ + ++ + +M E+E + ++ K + E + E+
Sbjct: 1744 AAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEA 1803
Query: 514 ERLREKEERMREQKKMWQQEE-KMREEKKTQEQEK----------KTWDQ---EEKMREE 559
RLR E + Q+++ +++ + R E + EK KT + +EK E
Sbjct: 1804 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1863
Query: 560 ERMR----EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
ER+R + + R EE + + ++E+ ++R+ + E+++ + E + Q
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1923
Query: 616 EK-------MWEQEEEDKMQEQEEM---MWEQEEKMQEQEEKMWE---QEEKMREQEEKM 662
E+ +E+ K + + E+ E+ ++ +E+ E Q + E+E +
Sbjct: 1924 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1983
Query: 663 REQEEKMQ----GQEEKMREQEEKMQGQEEKMREQEE--KMRGQEEKMWGQEEKMWGQEE 716
RE EE++Q +EE R+++ ++ E + EE ++R + E+ ++ ++ +
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043
Query: 717 KMWGQEEMREKEERIRDQKEKMQERLPEHE 746
+ Q E + ++ +++++Q+ L + +
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQ 2073
Score = 115 bits (288), Expect = 2e-25
Identities = 173/821 (21%), Positives = 342/821 (41%), Gaps = 149/821 (18%)
Query: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESK-- 127
E+E + EA R+ + ++ L + E E +Q+ A + ES+
Sbjct: 1451 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRK 1510
Query: 128 -----DLAGRLHHSWHFAGELQRALSAVSTWH---KKADRYIEELTKERDA---LSLELY 176
+LA R+ A E QRAL A+ ++A+R + + ER ++LE
Sbjct: 1511 RQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1570
Query: 177 RNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 236
+ + EL+ K A EK E E + V +L+ + ER Q + +EE
Sbjct: 1571 QRS-AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA--QQQAEAERAREEA 1627
Query: 237 WR-----------------QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279
R Q EE+ +Q+ + + EK + ER + GK EQ + R
Sbjct: 1628 ERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR 1687
Query: 280 RQEKRLREQEKELRE---QEKELREQKKLR--------EQEEQMQEQEEKMWEQEE---- 324
++ E++++L E Q++ EQ+ +R EQ+ Q+ E+E ++E
Sbjct: 1688 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1747
Query: 325 -----------KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE----ERMWEQDERLR 369
K+R + E + + R E+ + E+ ++ + E + E+ RLR
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807
Query: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK----MQKQEENMWEQ 425
E + Q ++ E++ Q E R +K+ E R + E +K+ EN +
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1867
Query: 426 ---EEKEWQQQRLPEQ--------KEKLWEQEKMQEQE-------------EKIWEQEE- 460
E++ +Q++RL EQ +E+L + K + E ++ +EE
Sbjct: 1868 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1927
Query: 461 ----------------------KIRDQEEMWGQEKKMWRQEKMR------EQEDQMWEQE 492
+IR E + K+ E R E+E + E E
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 493 EKMRDQ---EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
E+++ E++ Q + E+ ERL+ K E R ++ +QE R+ + QE +K
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA-RQLQLAQEAAQKR 2046
Query: 550 WDQEEKMRE---EERMREREKKMREEEEMM-------------REQEEKMQEQEEKMREQ 593
EEK +++ +E ++ +++E+ ++ E+ E+ + Q E+ Q
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 594 EEKMWEQEEKM-QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
+ E+ E++ Q EE+ + + E+ K EQE Q E+ ++++ + E
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2166
Query: 653 -EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
EK ++ E+ Q+ +++ + +R Q E+ Q+ + E+ ++++ + + Q ++
Sbjct: 2167 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2226
Query: 712 WGQEEKMWG----QEEMREKEERIRDQKEKMQERLPEHEER 748
EE+++ EE+ + + RI + + R ++ +R
Sbjct: 2227 ---EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2264
Score = 115 bits (287), Expect = 2e-25
Identities = 139/624 (22%), Positives = 276/624 (44%), Gaps = 57/624 (9%)
Query: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
EE KE A+ L T LKK A+ AE+++ EL+ E +
Sbjct: 1109 EEQLKEAQAVPATLPELEATKASLKKLRAQ-------AEAQQPTFDALRDELRGAQEVGE 1161
Query: 222 FLLPQVQTNTLQEEMWRQE-EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
L + ++ E WR+ +L E+ + + Q + R+ E+L Q RE + +
Sbjct: 1162 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1221
Query: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
+ R +++++ Q L + + +REQ Q Q E++ EK+ E + + +
Sbjct: 1222 WLQDARRRQEQI--QAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAI 1279
Query: 341 WEQEKQM------------REQEQKMRDQEERMWEQDERLREKEERMREQEKMW-----E 383
+ E Q+ ++ K++ E + ++ LR + + E
Sbjct: 1280 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1339
Query: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE---------NMWEQEEKEWQQQR 434
+M+EEER+ E+++ EE E + E E ++KQ + E+E KE QQ+
Sbjct: 1340 TLRRMEEEERLAEQQRA--EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRM 1397
Query: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
E + Q+Q+ I E+ +++R E Q K RQ + E+ E+E +
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA--RQAEAAERSRLRIEEEIR 1455
Query: 495 MRDQEQKMWDQEERMWEQD-ERLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTWDQ 552
+ + + +++ E + + LR + E QK+ Q+E E++R + + + Q K+ +
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1515
Query: 553 EEKMR---EEERMREREKKMREEEEMMREQEE---KMQEQEEKMREQEEKMWEQEEKMQE 606
E R E E RE+++ ++ EE+ + EE ++++ E + Q + E ++ E
Sbjct: 1516 ELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAE 1575
Query: 607 QEEKMWEQEEKMWEQEEEDKMQEQE----EMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
E + + E +QE+ ++ E E + Q+Q E +EE RE E
Sbjct: 1576 AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQ 1635
Query: 663 REQEE--KMQGQEEKMREQEEKMQGQEEKMREQ---EEKMRGQEEKMWGQEEKMWGQEEK 717
+ E +++ Q E++ +Q+ Q + EK +E+ E + RG+ E+ ++ ++ QE +
Sbjct: 1636 LKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1695
Query: 718 MWGQEEMREKEERIRDQKEKMQER 741
Q ++R+ ++E ++ R
Sbjct: 1696 KQRQLAEGTAQQRLAAEQELIRLR 1719
Score = 107 bits (266), Expect = 6e-23
Identities = 152/689 (22%), Positives = 290/689 (42%), Gaps = 118/689 (17%)
Query: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
+KA +E L K LS E +K L E A + +SE++L + +L+
Sbjct: 1027 QKAQAEVEGLGKGVARLSAEA-----------EKVLALPEPSPAAPTLRSELELTLGKLE 1075
Query: 215 RKLERAKFLLPQVQTNTL--------QEEMWRQEEELREQE----------------KKI 250
+ + L +++T +L +E + EE+L+E + KK+
Sbjct: 1076 QVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKL 1135
Query: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ-KKLREQE 309
R Q E + LR++ +E E+++++ + + RE+ +L E+ + + Q
Sbjct: 1136 RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQT 1195
Query: 310 EQMQEQEEKMWEQEEKMREQEEKM--WRQEERLWEQEKQMR--EQEQKMRD---QEERMW 362
+ Q + E++ Q RE + + W Q+ R +++ Q Q +R+ QE+ +
Sbjct: 1196 DVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL 1255
Query: 363 EQDERLREKEERMREQEKMWEQEEKMQE---------EERIREREKKMR----------- 402
E+ ER EK E + K + K E E + KK +
Sbjct: 1256 EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQE 1315
Query: 403 --------EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
E T+ Q K + E+EE+ +QQR E++E+L E E E++ +
Sbjct: 1316 YVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQR-AEERERLAEVEAALEKQRQ 1374
Query: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKM----------REQEDQMWEQEEKMRDQEQKMWD 504
+ E + + Q E +E + QE++ ++Q+ + E+ +++R +
Sbjct: 1375 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1434
Query: 505 QEERMWEQDERLREK-EERMREQKKMWQQEEKMR------------EEKKTQEQEKKTWD 551
+ R E ER R + EE +R + + E+ R ++ + Q+++ +
Sbjct: 1435 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1494
Query: 552 QEEKMR-----EEERMRERE----KKMREEEEMMREQEEKMQEQEE---KMREQEEKMWE 599
+ E++R E +R R+ E +++ E E RE++ +Q EE + E E ++ +
Sbjct: 1495 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1554
Query: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
E + Q + E ++ E E + K E + E +QE+ + + E E E
Sbjct: 1555 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLRE---EAE 1611
Query: 660 EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW 719
+ ++Q E + +EE RE E E +R +R Q E++ Q+ + EK
Sbjct: 1612 RRAQQQAEAERAREEAERELERWQLKANEALR-----LRLQAEEVAQQKSLAQAEAEK-- 1664
Query: 720 GQEEMREKEERIRDQKEKMQERLPEHEER 748
Q+E E+E R R + E+ R E E+
Sbjct: 1665 -QKEEAEREARRRGKAEEQAVRQRELAEQ 1692
Score = 94.4 bits (233), Expect = 4e-19
Identities = 110/477 (23%), Positives = 217/477 (45%), Gaps = 63/477 (13%)
Query: 72 EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG 131
+K Q LR ++E DH +L EL+ + +AAR+
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLD---EELQRLKAEATEAARQ-------------- 2222
Query: 132 RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNT--ITNEELKKKN 189
+++ L +V ++ + + E AL L NT EE +K
Sbjct: 2223 --------RSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK 2274
Query: 190 AELQEKLRL--AESEKSEI-QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
+E RL A E + + QL ++L ++ A+ +L + + + E EL +Q
Sbjct: 2275 QVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQ 2334
Query: 247 EKKI------RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
+K++ R QE+K ++ E +G R E + +RQ + E E+ + R
Sbjct: 2335 QKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSR 2394
Query: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Q + E ++ ++Q E E EK+ R E L QEK Q +++ Q+
Sbjct: 2395 AQARAEEDAQRFRKQAE----------EIGEKLHRTE--LATQEKVTLVQTLEIQRQQSD 2442
Query: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE--EKMQKQ 418
ERLRE + E+EK EK+Q+E ++ + + EE +T+++++ ++ Q
Sbjct: 2443 --HDAERLREAIAEL-EREK-----EKLQQEAKLLQLKS---EEMQTVQQEQLLQETQAL 2491
Query: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
+++ +++ Q++R EQ++ EQ E + +EE+ R Q++M ++++
Sbjct: 2492 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--EQERQRLV 2549
Query: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK 535
M E + E EE +R +++++ E++ +Q+E L E+ +R+REQ ++ +++ +
Sbjct: 2550 ASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2606
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.121 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,238,803
Number of Sequences: 37866
Number of extensions: 2683636
Number of successful extensions: 298290
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2095
Number of HSP's successfully gapped in prelim test: 1169
Number of HSP's that attempted gapping in prelim test: 20337
Number of HSP's gapped (non-prelim): 62697
length of query: 828
length of database: 18,247,518
effective HSP length: 111
effective length of query: 717
effective length of database: 14,044,392
effective search space: 10069829064
effective search space used: 10069829064
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.