Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 239744942
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239744942 PREDICTED: chromosome 14 open reading frame 25
[Homo sapiens]
(1614 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 3232 0.0
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 3230 0.0
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 3225 0.0
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 93 2e-18
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 93 2e-18
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 82 4e-15
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 82 4e-15
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 78 6e-14
gi|118766328 transmembrane and tetratricopeptide repeat containi... 71 7e-12
gi|118766330 transmembrane and tetratricopeptide repeat containi... 71 7e-12
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 70 2e-11
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 69 4e-11
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 66 2e-10
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 62 3e-09
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 61 8e-09
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 60 2e-08
gi|83415184 transmembrane and tetratricopeptide repeat containin... 60 2e-08
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 59 4e-08
gi|224809432 transmembrane and tetratricopeptide repeat containi... 59 5e-08
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 56 2e-07
gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens] 55 4e-07
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 55 5e-07
gi|22749211 transmembrane and tetratricopeptide repeat containin... 55 5e-07
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 54 2e-06
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 53 3e-06
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 52 5e-06
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 52 6e-06
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 48 7e-05
gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens] 47 1e-04
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 47 2e-04
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 3232 bits (8381), Expect = 0.0
Identities = 1614/1614 (100%), Positives = 1614/1614 (100%)
Query: 1 MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA 60
MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA
Sbjct: 1 MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA 60
Query: 61 RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF 120
RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF
Sbjct: 61 RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF 120
Query: 121 YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH 180
YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH
Sbjct: 121 YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH 180
Query: 181 LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR 240
LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR
Sbjct: 181 LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR 240
Query: 241 EAAGLGAQGEQESWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI 300
EAAGLGAQGEQESWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI
Sbjct: 241 EAAGLGAQGEQESWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI 300
Query: 301 RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM 360
RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM
Sbjct: 301 RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM 360
Query: 361 SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA 420
SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA
Sbjct: 361 SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA 420
Query: 421 KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE 480
KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE
Sbjct: 421 KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE 480
Query: 481 LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH 540
LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH
Sbjct: 481 LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH 540
Query: 541 IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET 600
IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET
Sbjct: 541 IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET 600
Query: 601 LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL 660
LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL
Sbjct: 601 LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL 660
Query: 661 RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES 720
RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES
Sbjct: 661 RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES 720
Query: 721 IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS 780
IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS
Sbjct: 721 IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS 780
Query: 781 KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR 840
KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR
Sbjct: 781 KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR 840
Query: 841 TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES 900
TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES
Sbjct: 841 TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES 900
Query: 901 EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI 960
EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI
Sbjct: 901 EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI 960
Query: 961 YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD 1020
YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD
Sbjct: 961 YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD 1020
Query: 1021 IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN
Sbjct: 1021 IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
Query: 1081 IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV 1140
IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV
Sbjct: 1081 IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV 1140
Query: 1141 LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYN 1200
LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYN
Sbjct: 1141 LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYN 1200
Query: 1201 LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL 1260
LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL
Sbjct: 1201 LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL 1260
Query: 1261 LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF 1320
LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF
Sbjct: 1261 LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF 1320
Query: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS
Sbjct: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
Query: 1381 FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST 1440
FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST
Sbjct: 1381 FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST 1440
Query: 1441 TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS 1500
TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS
Sbjct: 1441 TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS 1500
Query: 1501 KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY 1560
KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY
Sbjct: 1501 KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY 1560
Query: 1561 ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI
Sbjct: 1561 ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 3230 bits (8375), Expect = 0.0
Identities = 1613/1614 (99%), Positives = 1613/1614 (99%)
Query: 1 MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA 60
MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA
Sbjct: 1 MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA 60
Query: 61 RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF 120
RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF
Sbjct: 61 RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF 120
Query: 121 YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH 180
YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH
Sbjct: 121 YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH 180
Query: 181 LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR 240
LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR
Sbjct: 181 LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR 240
Query: 241 EAAGLGAQGEQESWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI 300
EAAGLGAQGEQESWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI
Sbjct: 241 EAAGLGAQGEQESWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI 300
Query: 301 RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM 360
RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM
Sbjct: 301 RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM 360
Query: 361 SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA 420
SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA
Sbjct: 361 SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA 420
Query: 421 KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE 480
KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE
Sbjct: 421 KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE 480
Query: 481 LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH 540
LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH
Sbjct: 481 LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH 540
Query: 541 IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET 600
IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET
Sbjct: 541 IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET 600
Query: 601 LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL 660
LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL
Sbjct: 601 LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL 660
Query: 661 RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES 720
RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES
Sbjct: 661 RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES 720
Query: 721 IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS 780
IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS
Sbjct: 721 IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS 780
Query: 781 KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR 840
KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR
Sbjct: 781 KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR 840
Query: 841 TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES 900
TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES
Sbjct: 841 TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES 900
Query: 901 EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI 960
EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI
Sbjct: 901 EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI 960
Query: 961 YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD 1020
YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD
Sbjct: 961 YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD 1020
Query: 1021 IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN
Sbjct: 1021 IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
Query: 1081 IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV 1140
IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV
Sbjct: 1081 IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV 1140
Query: 1141 LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYN 1200
LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYN
Sbjct: 1141 LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYN 1200
Query: 1201 LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL 1260
LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSY AFYNRALCYTKIRELQMALTDYGIVL
Sbjct: 1201 LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVL 1260
Query: 1261 LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF 1320
LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF
Sbjct: 1261 LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF 1320
Query: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS
Sbjct: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
Query: 1381 FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST 1440
FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST
Sbjct: 1381 FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST 1440
Query: 1441 TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS 1500
TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS
Sbjct: 1441 TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS 1500
Query: 1501 KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY 1560
KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY
Sbjct: 1501 KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY 1560
Query: 1561 ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI
Sbjct: 1561 ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 3225 bits (8362), Expect = 0.0
Identities = 1610/1614 (99%), Positives = 1611/1614 (99%)
Query: 1 MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA 60
MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA
Sbjct: 1 MSTIPRHFGLKYKEESYMFKELEKVRQETKKDFLRFKQKLASKPAVDESPVHSLHAPGPA 60
Query: 61 RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF 120
RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF
Sbjct: 61 RPARVSCAAARTSRRYPSLKGPAMSAAALLQEVLGGAPRPSGLGEAAAPGKTRSFRPRDF 120
Query: 121 YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH 180
YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH
Sbjct: 121 YLRSSAFLRHQALKKPPVIASGFGTARPVVLLPPPEPPVKRRARGVLESSRHAAPRRVFH 180
Query: 181 LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR 240
LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR
Sbjct: 181 LGREREQSQEVAPLAGPCMAKERKASSVSAEDGYMEASSGRRKVRIRSNFVSESGAREAR 240
Query: 241 EAAGLGAQGEQESWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI 300
EAAGLGAQGEQ+SWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI
Sbjct: 241 EAAGLGAQGEQDSWPPSDAREAAWQALLPSRVIPTSIEEIIASLQSEAQLASDQTIKELI 300
Query: 301 RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM 360
RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM
Sbjct: 301 RSVLGQNYDITMEDISLMGKMYLKTSPMQAETPEIQAEYKFQMGAEESQMSVHKELSETM 360
Query: 361 SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA 420
SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA
Sbjct: 361 SSILQIEQEDIEWGPSEAESIVFKPQEISQVQPAEELSKPLEDGQPTSDSKEAKWVSLTA 420
Query: 421 KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE 480
KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE
Sbjct: 421 KSPEFLQIEGKEIKRMRKRKSLRPRKSSKPLCDKKLHKKIPQDYSMPHLHDLCTTIPAQE 480
Query: 481 LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH 540
LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH
Sbjct: 481 LPVDLRLASRVYHTANRKGHDTLLGKFGTSFLDDRFTDEEQTDRILYGIPVMDDNQEYVH 540
Query: 541 IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET 600
IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET
Sbjct: 541 IPPTPQGIPPELAQGTRERAHKPHLEVLGEEMYAYPEFTKLFWNTAAPKFSVPESVMKET 600
Query: 601 LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL 660
LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL
Sbjct: 601 LYPKYESVQASRLLTDKLSYKSSVITLHQHSRTNFWCFLPRKSASFESIQKWFSAQPTQL 660
Query: 661 RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES 720
RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES
Sbjct: 661 RRVKSSVDLRKEKIIAPLEIKNDMQSSIKEVMFQKAKELKRQLQLTKQNKTEEPNYVKES 720
Query: 721 IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS 780
IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS
Sbjct: 721 IDDIFDNMCEKHSLRNLSLTLIEASKKAGISYIVYPKKKKMRWKKRLKQQKLIFVHEELS 780
Query: 781 KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR 840
KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR
Sbjct: 781 KPPKSLERSASHGILPGQKKYLFKVPLYERQIRCPSLPLYLNFEKFVQAKGGIPENIDPR 840
Query: 841 TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES 900
TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES
Sbjct: 841 TWALDRLIEYKDASIPVKEKDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYES 900
Query: 901 EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI 960
EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI
Sbjct: 901 EVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLI 960
Query: 961 YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD 1020
YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD
Sbjct: 961 YLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD 1020
Query: 1021 IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN
Sbjct: 1021 IYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
Query: 1081 IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV 1140
IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV
Sbjct: 1081 IDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEV 1140
Query: 1141 LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYN 1200
LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDA SHSDKGPDAT ISADCLYN
Sbjct: 1141 LDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDASSHSDKGPDATTISADCLYN 1200
Query: 1201 LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL 1260
LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSY AFYNRALCYTKIRELQMALTDYGIVL
Sbjct: 1201 LGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVL 1260
Query: 1261 LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF 1320
LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF
Sbjct: 1261 LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF 1320
Query: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS
Sbjct: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
Query: 1381 FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST 1440
FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST
Sbjct: 1381 FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST 1440
Query: 1441 TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS 1500
TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS
Sbjct: 1441 TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFS 1500
Query: 1501 KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY 1560
KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY
Sbjct: 1501 KALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQY 1560
Query: 1561 ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI
Sbjct: 1561 ELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 93.2 bits (230), Expect = 2e-18
Identities = 82/302 (27%), Positives = 128/302 (42%), Gaps = 18/302 (5%)
Query: 1314 HHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPA 1373
H + + + +F T A+K NP +AY GN Y E G ++A + + AL + P
Sbjct: 55 HFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQ---LQEAIEHYRHALRLKPD 111
Query: 1374 YIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDIN 1433
+I I+ L A G + A + A+ +P Y V +GN A+ +
Sbjct: 112 FIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLY-------CVRSDLGNLLKALGRLE 164
Query: 1434 AA-----MKISTTAEFL---TNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNI 1485
A I T F +N G + G A+ ++ A+TL+P + AY N GN+
Sbjct: 165 EAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNV 224
Query: 1486 YFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAA 1545
R F +A + +AL P + V N A + A + + IE P +
Sbjct: 225 LKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPD 284
Query: 1546 VYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 1605
Y N A+ AE+ N AL L P A N A ++ + G IEEA+ Y +AL
Sbjct: 285 AYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKAL 344
Query: 1606 DL 1607
++
Sbjct: 345 EV 346
Score = 77.4 bits (189), Expect = 1e-13
Identities = 76/291 (26%), Positives = 119/291 (40%), Gaps = 27/291 (9%)
Query: 1200 NLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIV 1259
NLG + +G + LAI A+++D N A+ N + R A+ Y
Sbjct: 186 NLGCVFNAQGEIW----LAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRA 241
Query: 1260 LLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA-LISRTNGSLCHATAMCHHRIN 1318
L L V N +Y E G A++ +++A L + C+ +
Sbjct: 242 LSLSPNHAVVHG---NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEK-G 297
Query: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
EA + + AL++ P D+ N E G+ E +A + + KAL + P + A
Sbjct: 298 SVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIE---EAVRLYRKALEVFPEFAAAH 354
Query: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI 1438
+ LQ QGK Q+A H+ AI P AY MGN MQD+ A++
Sbjct: 355 SNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN-------MGNTLKEMQDVQGALQC 407
Query: 1439 STTA--------EFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFN 1481
T A + +N IH+ G+ A+ Y+ A+ L P + AY N
Sbjct: 408 YTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCN 458
Score = 73.6 bits (179), Expect = 1e-12
Identities = 67/286 (23%), Positives = 128/286 (44%), Gaps = 9/286 (3%)
Query: 1225 AISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELG 1284
AI N A+ N + E+ +A+ + + LD L+ ++N G + E
Sbjct: 173 AIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF---LDAYINLGNVLKEAR 229
Query: 1285 QYGFALEDFKQAALISRTNGSLCHATAMC-HHRINEFEEAVNFFTWALKINPCFLDAYVG 1343
+ A+ + +A +S N ++ H C ++ + A++ + A+++ P F DAY
Sbjct: 230 IFDRAVAAYLRALSLS-PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCN 288
Query: 1344 RGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAID 1403
N+ E G + +A+ + AL + P + + + + QG ++A + A++
Sbjct: 289 LANALKEKG---SVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALE 345
Query: 1404 TDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAM 1462
P+ A+ A V Q G A+ A++IS T A+ +N G + M Q A+
Sbjct: 346 VFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGAL 405
Query: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPE 1508
+ Y AI +NP ++ A+ N +I+ +A + ALK P+
Sbjct: 406 QCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 451
Score = 72.8 bits (177), Expect = 3e-12
Identities = 96/394 (24%), Positives = 152/394 (38%), Gaps = 61/394 (15%)
Query: 1264 ATETVKLNTFL-----NRGLIYVELGQYGFALEDFKQAALISRT--NGSLCHATAMCHHR 1316
+T +K N L N G +Y E GQ A+E ++ A + +G + A A+
Sbjct: 68 STLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALV--A 125
Query: 1317 INEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIK 1376
+ E AV + AL+ NP GN G E K +LKA+ P +
Sbjct: 126 AGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKAC---YLKAIETQPNFAV 182
Query: 1377 ARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAM 1436
A + G AQG+ A +HF A+ DP AY + +GN + + A+
Sbjct: 183 AWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAY-------INLGNVLKEARIFDRAV 235
Query: 1437 KISTTAEFLT-NRGVIHEFMG---HKQN----AMKDYQDAITLNPKYSLAYFNAGNIYFH 1488
A L+ N V+H + ++Q A+ Y+ AI L P + AY N N
Sbjct: 236 AAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKE 295
Query: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548
++A D ++ AL+ P + L N A EEA + +E P +AA +
Sbjct: 296 KGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHS 355
Query: 1549 NRA--------------HFYYCLK--------------------QYELAEEDLNKALSLK 1574
N A H+ ++ + A + +A+ +
Sbjct: 356 NLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQIN 415
Query: 1575 PNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
P A ++ A + G I EA+A Y AL L+
Sbjct: 416 PAFADAHSNLASIHKDSGNIPEAIASYRTALKLK 449
Score = 57.4 bits (137), Expect = 1e-07
Identities = 91/426 (21%), Positives = 155/426 (36%), Gaps = 49/426 (11%)
Query: 917 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNY 976
A AY G +Y++ G+LQ A+ + + L+P F++ Y + + + A+
Sbjct: 79 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVS 138
Query: 977 IHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV- 1035
+YN + + + + A Y +AI++ P A + G ++ ++
Sbjct: 139 ALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW 198
Query: 1036 LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLM 1095
LAI F K + DP DA + G E + A+ + L++ ++ G L
Sbjct: 199 LAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGN--LA 256
Query: 1096 MKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCA 1155
YY +Q LI + + +AIE+ C
Sbjct: 257 CVYY-----------------------EQGLIDLAIDTYRRAIELQP-----HFPDAYCN 288
Query: 1156 LLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTY 1215
L ++ K EA + AL AD L NL E+GN++
Sbjct: 289 LANALKEKGS-VAEAEDCYNTAL----------RLCPTHADSLNNLANIKREQGNIEEAV 337
Query: 1216 KLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLN 1275
+L A+ + A N A + +LQ AL Y + + T + + N
Sbjct: 338 RL----YRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA---DAYSN 390
Query: 1276 RGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINP 1335
G E+ AL+ + +A I+ A H EA+ + ALK+ P
Sbjct: 391 MGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 450
Query: 1336 CFLDAY 1341
F DAY
Sbjct: 451 DFPDAY 456
Score = 36.2 bits (82), Expect = 0.26
Identities = 32/152 (21%), Positives = 65/152 (42%), Gaps = 8/152 (5%)
Query: 926 IYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNT 985
I R+ G ++ A+ ++ + + P F A+ + + Q K+ EAL + +
Sbjct: 326 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 385
Query: 986 EAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKC 1044
+AY + + +D+ A+ YT+AI+ P AD + +++ + + AI +
Sbjct: 386 DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTA 445
Query: 1045 IFYDPKRTDALLKRGLFYCENENWFAAIEDFT 1076
+ P DA YC + + D+T
Sbjct: 446 LKLKPDFPDA-------YCNLAHCLQIVCDWT 470
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 93.2 bits (230), Expect = 2e-18
Identities = 82/302 (27%), Positives = 128/302 (42%), Gaps = 18/302 (5%)
Query: 1314 HHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPA 1373
H + + + +F T A+K NP +AY GN Y E G ++A + + AL + P
Sbjct: 65 HFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQ---LQEAIEHYRHALRLKPD 121
Query: 1374 YIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDIN 1433
+I I+ L A G + A + A+ +P Y V +GN A+ +
Sbjct: 122 FIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLY-------CVRSDLGNLLKALGRLE 174
Query: 1434 AA-----MKISTTAEFL---TNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNI 1485
A I T F +N G + G A+ ++ A+TL+P + AY N GN+
Sbjct: 175 EAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNV 234
Query: 1486 YFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAA 1545
R F +A + +AL P + V N A + A + + IE P +
Sbjct: 235 LKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPD 294
Query: 1546 VYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 1605
Y N A+ AE+ N AL L P A N A ++ + G IEEA+ Y +AL
Sbjct: 295 AYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKAL 354
Query: 1606 DL 1607
++
Sbjct: 355 EV 356
Score = 77.4 bits (189), Expect = 1e-13
Identities = 76/291 (26%), Positives = 119/291 (40%), Gaps = 27/291 (9%)
Query: 1200 NLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIV 1259
NLG + +G + LAI A+++D N A+ N + R A+ Y
Sbjct: 196 NLGCVFNAQGEIW----LAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRA 251
Query: 1260 LLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA-LISRTNGSLCHATAMCHHRIN 1318
L L V N +Y E G A++ +++A L + C+ +
Sbjct: 252 LSLSPNHAVVHG---NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEK-G 307
Query: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
EA + + AL++ P D+ N E G+ E +A + + KAL + P + A
Sbjct: 308 SVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIE---EAVRLYRKALEVFPEFAAAH 364
Query: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI 1438
+ LQ QGK Q+A H+ AI P AY MGN MQD+ A++
Sbjct: 365 SNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN-------MGNTLKEMQDVQGALQC 417
Query: 1439 STTA--------EFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFN 1481
T A + +N IH+ G+ A+ Y+ A+ L P + AY N
Sbjct: 418 YTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCN 468
Score = 73.6 bits (179), Expect = 1e-12
Identities = 67/286 (23%), Positives = 128/286 (44%), Gaps = 9/286 (3%)
Query: 1225 AISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELG 1284
AI N A+ N + E+ +A+ + + LD L+ ++N G + E
Sbjct: 183 AIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF---LDAYINLGNVLKEAR 239
Query: 1285 QYGFALEDFKQAALISRTNGSLCHATAMC-HHRINEFEEAVNFFTWALKINPCFLDAYVG 1343
+ A+ + +A +S N ++ H C ++ + A++ + A+++ P F DAY
Sbjct: 240 IFDRAVAAYLRALSLS-PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCN 298
Query: 1344 RGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAID 1403
N+ E G + +A+ + AL + P + + + + QG ++A + A++
Sbjct: 299 LANALKEKG---SVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALE 355
Query: 1404 TDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAM 1462
P+ A+ A V Q G A+ A++IS T A+ +N G + M Q A+
Sbjct: 356 VFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGAL 415
Query: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPE 1508
+ Y AI +NP ++ A+ N +I+ +A + ALK P+
Sbjct: 416 QCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 461
Score = 72.8 bits (177), Expect = 3e-12
Identities = 96/394 (24%), Positives = 152/394 (38%), Gaps = 61/394 (15%)
Query: 1264 ATETVKLNTFL-----NRGLIYVELGQYGFALEDFKQAALISRT--NGSLCHATAMCHHR 1316
+T +K N L N G +Y E GQ A+E ++ A + +G + A A+
Sbjct: 78 STLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALV--A 135
Query: 1317 INEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIK 1376
+ E AV + AL+ NP GN G E K +LKA+ P +
Sbjct: 136 AGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKAC---YLKAIETQPNFAV 192
Query: 1377 ARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAM 1436
A + G AQG+ A +HF A+ DP AY + +GN + + A+
Sbjct: 193 AWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAY-------INLGNVLKEARIFDRAV 245
Query: 1437 KISTTAEFLT-NRGVIHEFMG---HKQN----AMKDYQDAITLNPKYSLAYFNAGNIYFH 1488
A L+ N V+H + ++Q A+ Y+ AI L P + AY N N
Sbjct: 246 AAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKE 305
Query: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548
++A D ++ AL+ P + L N A EEA + +E P +AA +
Sbjct: 306 KGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHS 365
Query: 1549 NRA--------------HFYYCLK--------------------QYELAEEDLNKALSLK 1574
N A H+ ++ + A + +A+ +
Sbjct: 366 NLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQIN 425
Query: 1575 PNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
P A ++ A + G I EA+A Y AL L+
Sbjct: 426 PAFADAHSNLASIHKDSGNIPEAIASYRTALKLK 459
Score = 57.4 bits (137), Expect = 1e-07
Identities = 91/426 (21%), Positives = 155/426 (36%), Gaps = 49/426 (11%)
Query: 917 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNY 976
A AY G +Y++ G+LQ A+ + + L+P F++ Y + + + A+
Sbjct: 89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVS 148
Query: 977 IHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV- 1035
+YN + + + + A Y +AI++ P A + G ++ ++
Sbjct: 149 ALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW 208
Query: 1036 LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLM 1095
LAI F K + DP DA + G E + A+ + L++ ++ G L
Sbjct: 209 LAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGN--LA 266
Query: 1096 MKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCA 1155
YY +Q LI + + +AIE+ C
Sbjct: 267 CVYY-----------------------EQGLIDLAIDTYRRAIELQP-----HFPDAYCN 298
Query: 1156 LLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTY 1215
L ++ K EA + AL AD L NL E+GN++
Sbjct: 299 LANALKEKGS-VAEAEDCYNTAL----------RLCPTHADSLNNLANIKREQGNIEEAV 347
Query: 1216 KLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLN 1275
+L A+ + A N A + +LQ AL Y + + T + + N
Sbjct: 348 RL----YRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA---DAYSN 400
Query: 1276 RGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINP 1335
G E+ AL+ + +A I+ A H EA+ + ALK+ P
Sbjct: 401 MGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 460
Query: 1336 CFLDAY 1341
F DAY
Sbjct: 461 DFPDAY 466
Score = 36.2 bits (82), Expect = 0.26
Identities = 32/152 (21%), Positives = 65/152 (42%), Gaps = 8/152 (5%)
Query: 926 IYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNT 985
I R+ G ++ A+ ++ + + P F A+ + + Q K+ EAL + +
Sbjct: 336 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 395
Query: 986 EAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKC 1044
+AY + + +D+ A+ YT+AI+ P AD + +++ + + AI +
Sbjct: 396 DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTA 455
Query: 1045 IFYDPKRTDALLKRGLFYCENENWFAAIEDFT 1076
+ P DA YC + + D+T
Sbjct: 456 LKLKPDFPDA-------YCNLAHCLQIVCDWT 480
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapiens]
Length = 830
Score = 82.0 bits (201), Expect = 4e-15
Identities = 52/194 (26%), Positives = 99/194 (51%), Gaps = 8/194 (4%)
Query: 1423 GNNFAAMQDINAAMKISTTA-EFLTNRGVIHEFMGHK-------QNAMKDYQDAITLNPK 1474
GN F+ ++ + A+K A + N + +GH+ A+ +++AI +NP+
Sbjct: 580 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 639
Query: 1475 YSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534
+ A++ G IY+ +FS A +F KAL +P++ +L + + LKK E+A +
Sbjct: 640 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 699
Query: 1535 NVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594
I P F+RA + ++Y+ A ++L + + P ++LVY KV K+G
Sbjct: 700 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 759
Query: 1595 EEAMADYNQALDLE 1608
A+ +++ A+DL+
Sbjct: 760 HLALMNFSWAMDLD 773
Score = 65.5 bits (158), Expect = 4e-10
Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 4/221 (1%)
Query: 1309 ATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKAL 1368
A C E + A+ FF A++++P + AY G+ E+ E +A F A+
Sbjct: 578 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFVLTEELDKALACFRNAI 634
Query: 1369 HINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAA 1428
+NP + A G Q KF A HF A+D +P++ + VV + + A
Sbjct: 635 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 694
Query: 1429 MQDINAAMKISTTAEFLTNRGVIHEFMGHK-QNAMKDYQDAITLNPKYSLAYFNAGNIYF 1487
+ +N A+ I F K ++A+++ ++ + PK SL YF G +Y
Sbjct: 695 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 754
Query: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEE 1528
Q A FS A+ DP+ + AI L EE
Sbjct: 755 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEE 795
Score = 59.7 bits (143), Expect = 2e-08
Identities = 71/315 (22%), Positives = 126/315 (40%), Gaps = 51/315 (16%)
Query: 1275 NRGLIYVELGQYGFALEDFKQAALIS---------RTNGSLCHATAMCHHRINEFEEAVN 1325
N G + ++G+ F L ++ QA I R G ++T + H + + ++
Sbjct: 503 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 562
Query: 1326 F-FTWALKINPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383
T K +P +A+ GN + ++ HD A K F +A+ ++P Y A G+
Sbjct: 563 KDLTDMDKNSP---EAWCAAGNCFSLQREHDIAIKF----FQRAIQVDPNYAYAYTLLGH 615
Query: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAE 1443
+ KA F AI +P++Y A+ G
Sbjct: 616 EFVLTEELDKALACFRNAIRVNPRHYNAWYGL---------------------------- 647
Query: 1444 FLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKAL 1503
G+I+ A +Q A+ +NP+ S+ + G + ++ +A D +KA+
Sbjct: 648 -----GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 702
Query: 1504 KFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA 1563
DP+N +RA +KY+ A ++ + + P + VYF Y L Q LA
Sbjct: 703 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 762
Query: 1564 EEDLNKALSLKPNDA 1578
+ + A+ L P A
Sbjct: 763 LMNFSWAMDLDPKGA 777
Score = 52.4 bits (124), Expect = 4e-06
Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Query: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961
+ +L++++ D K A+C G + + A+ QR I ++P + AY +
Sbjct: 558 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 617
Query: 962 LFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADI 1021
+ +++++AL + N + A+ IY ++ +LA +++ +A+ P + +
Sbjct: 618 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 677
Query: 1022 YFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
G + K A+D +K I DPK R NE + +A+++ L
Sbjct: 678 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 737
Query: 1081 IDHQNSQARGQYLLMMKYY 1099
I + S Y L+ K Y
Sbjct: 738 IVPKESLV---YFLIGKVY 753
Score = 49.7 bits (117), Expect = 2e-05
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 10/152 (6%)
Query: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
KD D +P+ A+ AGN + R+ A +F +A++ DP Y +
Sbjct: 563 KDLTDMDKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 619
Query: 1523 LKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582
++ ++A F N I P ++ YY +++ LAE KAL + P +++
Sbjct: 620 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL- 678
Query: 1583 FRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
IG+++ A+ +ALD + A VI
Sbjct: 679 ------CHIGVVQHALKKSEKALDTLNKAIVI 704
Score = 42.0 bits (97), Expect = 0.005
Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 4/128 (3%)
Query: 897 YYESEVKILTE----EINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLN 952
YY+ E L E + D + C G + L K + A++ L + I+++P
Sbjct: 651 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 710
Query: 953 AYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAI 1012
+HR + +K AL +L + + + Y ++Y+ LA++N++ A+
Sbjct: 711 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 770
Query: 1013 KSTPTDAD 1020
P A+
Sbjct: 771 DLDPKGAN 778
Score = 39.3 bits (90), Expect = 0.031
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 21/194 (10%)
Query: 907 EEINDKTKYPAFAY------CRRGAIYRKLGKLQSAMNDLQRVILLE-------PLFLNA 953
E IN + P+ Y C+ G Y +L + A V +E ++
Sbjct: 489 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 548
Query: 954 YWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIK 1013
WH +++ L D++ KN+ EA+ + + +++ +AI + +AI+
Sbjct: 549 LWHLQKDVALS-VLSKDLTDMD------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 601
Query: 1014 STPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAI 1072
P A Y G + +T ++ A+ F I +P+ +A G+ Y + E + A
Sbjct: 602 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 661
Query: 1073 EDFTALLNIDHQNS 1086
F L+I+ Q+S
Sbjct: 662 MHFQKALDINPQSS 675
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapiens]
Length = 824
Score = 82.0 bits (201), Expect = 4e-15
Identities = 52/194 (26%), Positives = 99/194 (51%), Gaps = 8/194 (4%)
Query: 1423 GNNFAAMQDINAAMKISTTA-EFLTNRGVIHEFMGHK-------QNAMKDYQDAITLNPK 1474
GN F+ ++ + A+K A + N + +GH+ A+ +++AI +NP+
Sbjct: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633
Query: 1475 YSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534
+ A++ G IY+ +FS A +F KAL +P++ +L + + LKK E+A +
Sbjct: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693
Query: 1535 NVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594
I P F+RA + ++Y+ A ++L + + P ++LVY KV K+G
Sbjct: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753
Query: 1595 EEAMADYNQALDLE 1608
A+ +++ A+DL+
Sbjct: 754 HLALMNFSWAMDLD 767
Score = 65.5 bits (158), Expect = 4e-10
Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 4/221 (1%)
Query: 1309 ATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKAL 1368
A C E + A+ FF A++++P + AY G+ E+ E +A F A+
Sbjct: 572 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFVLTEELDKALACFRNAI 628
Query: 1369 HINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAA 1428
+NP + A G Q KF A HF A+D +P++ + VV + + A
Sbjct: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688
Query: 1429 MQDINAAMKISTTAEFLTNRGVIHEFMGHK-QNAMKDYQDAITLNPKYSLAYFNAGNIYF 1487
+ +N A+ I F K ++A+++ ++ + PK SL YF G +Y
Sbjct: 689 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 748
Query: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEE 1528
Q A FS A+ DP+ + AI L EE
Sbjct: 749 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEE 789
Score = 59.7 bits (143), Expect = 2e-08
Identities = 71/315 (22%), Positives = 126/315 (40%), Gaps = 51/315 (16%)
Query: 1275 NRGLIYVELGQYGFALEDFKQAALIS---------RTNGSLCHATAMCHHRINEFEEAVN 1325
N G + ++G+ F L ++ QA I R G ++T + H + + ++
Sbjct: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556
Query: 1326 F-FTWALKINPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383
T K +P +A+ GN + ++ HD A K F +A+ ++P Y A G+
Sbjct: 557 KDLTDMDKNSP---EAWCAAGNCFSLQREHDIAIKF----FQRAIQVDPNYAYAYTLLGH 609
Query: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAE 1443
+ KA F AI +P++Y A+ G
Sbjct: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGL---------------------------- 641
Query: 1444 FLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKAL 1503
G+I+ A +Q A+ +NP+ S+ + G + ++ +A D +KA+
Sbjct: 642 -----GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696
Query: 1504 KFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA 1563
DP+N +RA +KY+ A ++ + + P + VYF Y L Q LA
Sbjct: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756
Query: 1564 EEDLNKALSLKPNDA 1578
+ + A+ L P A
Sbjct: 757 LMNFSWAMDLDPKGA 771
Score = 52.4 bits (124), Expect = 4e-06
Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Query: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961
+ +L++++ D K A+C G + + A+ QR I ++P + AY +
Sbjct: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611
Query: 962 LFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADI 1021
+ +++++AL + N + A+ IY ++ +LA +++ +A+ P + +
Sbjct: 612 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
Query: 1022 YFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
G + K A+D +K I DPK R NE + +A+++ L
Sbjct: 672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 731
Query: 1081 IDHQNSQARGQYLLMMKYY 1099
I + S Y L+ K Y
Sbjct: 732 IVPKESLV---YFLIGKVY 747
Score = 49.7 bits (117), Expect = 2e-05
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 10/152 (6%)
Query: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
KD D +P+ A+ AGN + R+ A +F +A++ DP Y +
Sbjct: 557 KDLTDMDKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
Query: 1523 LKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582
++ ++A F N I P ++ YY +++ LAE KAL + P +++
Sbjct: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL- 672
Query: 1583 FRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
IG+++ A+ +ALD + A VI
Sbjct: 673 ------CHIGVVQHALKKSEKALDTLNKAIVI 698
Score = 42.0 bits (97), Expect = 0.005
Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 4/128 (3%)
Query: 897 YYESEVKILTE----EINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLN 952
YY+ E L E + D + C G + L K + A++ L + I+++P
Sbjct: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704
Query: 953 AYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAI 1012
+HR + +K AL +L + + + Y ++Y+ LA++N++ A+
Sbjct: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764
Query: 1013 KSTPTDAD 1020
P A+
Sbjct: 765 DLDPKGAN 772
Score = 39.3 bits (90), Expect = 0.031
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 21/194 (10%)
Query: 907 EEINDKTKYPAFAY------CRRGAIYRKLGKLQSAMNDLQRVILLE-------PLFLNA 953
E IN + P+ Y C+ G Y +L + A V +E ++
Sbjct: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 542
Query: 954 YWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIK 1013
WH +++ L D++ KN+ EA+ + + +++ +AI + +AI+
Sbjct: 543 LWHLQKDVALS-VLSKDLTDMD------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595
Query: 1014 STPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAI 1072
P A Y G + +T ++ A+ F I +P+ +A G+ Y + E + A
Sbjct: 596 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655
Query: 1073 EDFTALLNIDHQNS 1086
F L+I+ Q+S
Sbjct: 656 MHFQKALDINPQSS 669
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog A
[Homo sapiens]
Length = 608
Score = 78.2 bits (191), Expect = 6e-14
Identities = 111/493 (22%), Positives = 190/493 (38%), Gaps = 76/493 (15%)
Query: 1004 AILNYTQAIKSTPTDADI-----YFRRGEMYEITNKVLAI-DDFSKCIFYDPKRTDALLK 1057
AI YT+AI PT+ ++ Y R +E K + D +K + +PK AL +
Sbjct: 133 AIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFR 192
Query: 1058 RGLFYCENENWFAAIEDFTALLNID---HQNSQARGQYLLMMKYYDLAKFTIYQIAEMDK 1114
R + + +N +ED TA+ ++ +Q S +L + + AK E K
Sbjct: 193 RAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAK-------EKYK 245
Query: 1115 GLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVL 1174
L P Q + F D ++++ +K +++ E
Sbjct: 246 NREPLMPSPQFIKSYFSSFTDD-------------------IISQPMLKGEKSDE----- 281
Query: 1175 KKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMD-KNSY 1233
DK +A + + Y YMEE N Y I++ + I + K
Sbjct: 282 --------DKDKEGEALEVKENSGYLKAKQYMEEEN----YDKIISECSKEIDAEGKYMA 329
Query: 1234 TAFYNRALCYTKIRELQMALTDYG-IVLLLDATETVKLNTFLNRGLIYVELGQYGFALED 1292
A RA Y I A D ++ L +A ++ N + RG +Y++ Q + +D
Sbjct: 330 EALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQD 389
Query: 1293 FKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINP---------CFL---DA 1340
F AA I N + H +++ EEAV F +++ P CF A
Sbjct: 390 FNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQA 449
Query: 1341 YVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTI 1400
Y G +S ++ A K F + + P + + L Q +F KA +
Sbjct: 450 YTGNNSSQIQ--------AAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDK 501
Query: 1401 AIDTDPKNYLAYEGRAVVCLQMGNNF-AAMQDINAAMKISTTAEF-LTNRGVIHEFMGHK 1458
ID +P N Y + ++ LQ + ++ I+ A++I +F G I G+
Sbjct: 502 CIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNM 561
Query: 1459 QNAMKDYQDAITL 1471
+ A+ + AI L
Sbjct: 562 EKAIDMFNKAINL 574
Score = 51.6 bits (122), Expect = 6e-06
Identities = 73/327 (22%), Positives = 130/327 (39%), Gaps = 53/327 (16%)
Query: 1314 HHRINEFEEAVNFFTWALKINPCF--LDAYVGRGNSYMEYGHDEATKQAQKDFLKALHIN 1371
+ + ++E+A+ +T A+ + P +D N + + K+ +D KA+ +N
Sbjct: 124 YFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELN 183
Query: 1372 PAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQD 1431
P Y+KA F++A H + D K + AV L+ N +M
Sbjct: 184 PKYVKAL------------FRRAKAHEKL----DNKKECLEDVTAVCILEGFQNQQSMLL 227
Query: 1432 INAAMKI---STTAEFLTNR-------------------GVIHEFM--GHKQNAMKDYQD 1467
+ +K+ E NR +I + M G K + KD ++
Sbjct: 228 ADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKD-KE 286
Query: 1468 AITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYV---LMNRAITNTILK 1524
L K + Y A Y + + SK + D E +Y+ L+ RA ++
Sbjct: 287 GEALEVKENSGYLKAKQ-YMEEENYDKIISECSKEI--DAEGKYMAEALLLRATFYLLIG 343
Query: 1525 KYEEAKEDFANVIE----SCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALV 1580
AK D VI + A R Y +Q L+ +D N A + P +A V
Sbjct: 344 NANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADV 403
Query: 1581 YNFRAKVRGKIGLIEEAMADYNQALDL 1607
Y+ R +++ + +EEA+AD+++ + L
Sbjct: 404 YHHRGQLKILLDQVEEAVADFDECIRL 430
Score = 48.5 bits (114), Expect = 5e-05
Identities = 51/225 (22%), Positives = 94/225 (41%), Gaps = 20/225 (8%)
Query: 1371 NPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEG--RAVVCLQMGNNFAA 1428
N Y+KA+ + + K + + ID + K Y+A RA L +GN AA
Sbjct: 295 NSGYLKAK-----QYMEEENYDKIISECSKEIDAEGK-YMAEALLLRATFYLLIGNANAA 348
Query: 1429 MQDINAAMKISTT-----AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAG 1483
D++ + + A L RG ++ + +D+ A ++P+ + Y + G
Sbjct: 349 KPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRG 408
Query: 1484 NIYFHHRQFSQASDYFSKALKFDPENE-------YVLMNRAITNTILKKYEEAKEDFANV 1536
+ Q +A F + ++ PE+ + L +A T + + A + F V
Sbjct: 409 QLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEV 468
Query: 1537 IESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVY 1581
I+ P A Y A +Q+ A+E +K + L+P++A Y
Sbjct: 469 IKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTY 513
Score = 40.8 bits (94), Expect = 0.011
Identities = 49/244 (20%), Positives = 92/244 (37%), Gaps = 27/244 (11%)
Query: 914 KYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDD 973
K A A +RG++Y + + + D ++P + Y HR + + D++ EA+ D
Sbjct: 364 KLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVAD 423
Query: 974 LNYIHKYNKNNTEAYLSKA-EIYR------GKKDITLAILNYTQAIKSTPTDADIYFRRG 1026
+ + + A K +YR I A+ + + IK P A+ Y
Sbjct: 424 FDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYA 483
Query: 1027 EMYEITNKVLAIDD-FSKCIFYDPKRTDALLKRGLFYCE-NENWFAAIEDFTALLNIDHQ 1084
+ + D+ + KCI +P + +GL + ++ +E + + ID++
Sbjct: 484 QALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNK 543
Query: 1085 NSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSEL--------SPMQQALIYSFCENHDK 1136
A Y+ Q M+K + S M+ A +YS C+
Sbjct: 544 CDFA----------YETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHA 593
Query: 1137 AIEV 1140
EV
Sbjct: 594 QTEV 597
Score = 40.4 bits (93), Expect = 0.014
Identities = 38/192 (19%), Positives = 75/192 (39%), Gaps = 15/192 (7%)
Query: 1339 DAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR----ISFGYNLQAQGKFQKA 1394
+A + R Y+ G+ A K D K + + A +K R I G Q + +
Sbjct: 330 EALLLRATFYLLIGNANAAKP---DLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLS 386
Query: 1395 WNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEF--------LT 1446
F +A D DP+N Y R + + + A+ D + +++ + L
Sbjct: 387 TQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALY 446
Query: 1447 NRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFD 1506
+ Q AMK +++ I P+ + Y +QF +A + + K + +
Sbjct: 447 RQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLE 506
Query: 1507 PENEYVLMNRAI 1518
P+N +++ +
Sbjct: 507 PDNATTYVHKGL 518
Score = 38.1 bits (87), Expect = 0.069
Identities = 83/403 (20%), Positives = 149/403 (36%), Gaps = 58/403 (14%)
Query: 1262 LDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHAT-----AMCHHR 1316
LD + N+G Y + G+Y A++ + +A + T ++ +T A +
Sbjct: 106 LDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQ 165
Query: 1317 INEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGH-----DEATK-------QAQKDF 1364
+ +++E T A+++NP ++ A R ++ + + ++ T Q Q+
Sbjct: 166 LQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSM 225
Query: 1365 LKALHINPAYIKARISFGYN----LQAQGKFQKAW-NHFTIAIDTDPK-------NYLAY 1412
L A + K + Y L +F K++ + FT I + P
Sbjct: 226 LLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDK 285
Query: 1413 EGRAVVCLQMGNNFAAMQ----------------DINAAMKISTTAEFLTNRGVIHEFMG 1456
EG A+ + A Q +I+A K AE L R + +G
Sbjct: 286 EGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYM--AEALLLRATFYLLIG 343
Query: 1457 HKQNAMKDYQDAITLNPKYSLAYFNA----GNIYFHHRQFSQASDYFSKALKFDPENEYV 1512
+ A D I+L NA G++Y +Q ++ F+ A DP+N V
Sbjct: 344 NANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADV 403
Query: 1513 LMNRAITNTILKKYEEAKEDFANVIESCPFWAA-------VYFNRAHFYYCLKQYELAEE 1565
+R +L + EEA DF I P A + +A+ Q + A +
Sbjct: 404 YHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMK 463
Query: 1566 DLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
+ + P A Y A+ +A Y++ +DLE
Sbjct: 464 GFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLE 506
Score = 37.0 bits (84), Expect = 0.15
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 5/91 (5%)
Query: 1525 KYEEAKEDFANVIESCPFWAAV-----YFNRAHFYYCLKQYELAEEDLNKALSLKPNDAL 1579
KYE+A + + I CP V Y NRA + L++++ +D KA+ L P
Sbjct: 129 KYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVK 188
Query: 1580 VYNFRAKVRGKIGLIEEAMADYNQALDLEDY 1610
RAK K+ +E + D LE +
Sbjct: 189 ALFRRAKAHEKLDNKKECLEDVTAVCILEGF 219
Score = 32.3 bits (72), Expect = 3.8
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
Query: 879 KLKLNDYVESDLPQEVIKYYESEVKILTEEIN-DKTKYPAFAYCRRGAIYRKLGKLQSAM 937
K K N Y ++ ++ I+ Y + + E N D + + Y R A + +L K +
Sbjct: 118 KNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTF----YQNRAAAFEQLQKWKEVA 173
Query: 938 NDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYI 977
D + + L P ++ A + R + D E L+D+ +
Sbjct: 174 QDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAV 213
>gi|118766328 transmembrane and tetratricopeptide repeat containing 4
isoform 2 [Homo sapiens]
Length = 741
Score = 71.2 bits (173), Expect = 7e-12
Identities = 66/294 (22%), Positives = 130/294 (44%), Gaps = 4/294 (1%)
Query: 1304 GSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKD 1363
G L T C R E+ F AL + P + G + + G+ A A +
Sbjct: 448 GILFINTLRCVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTA---AIRY 504
Query: 1364 FLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMG 1423
+ +A+ +NP Y+ A + G L+ + + Q+A ++A+ P A+ +V +
Sbjct: 505 YREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLK 564
Query: 1424 NNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNA 1482
AA Q A+K + N G ++ + +A+ +++A L P++SLA+ N
Sbjct: 565 RFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNM 624
Query: 1483 GNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPF 1542
+ + +QA +AL+ P + ++ + A +KY+E++ F I++ P
Sbjct: 625 IILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPN 684
Query: 1543 WAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEE 1596
A+ + N A Y+ +LA++ +L L P + +R K+ L+++
Sbjct: 685 AASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRRKLELMQK 738
Score = 70.1 bits (170), Expect = 2e-11
Identities = 43/152 (28%), Positives = 73/152 (48%)
Query: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN 1515
G++ A++ Y++A+ LNPKY A N GNI + +A + S A++ P+ MN
Sbjct: 496 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMN 555
Query: 1516 RAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKP 1575
I LK++E A++ + I+ + Y+N Y L ++ A A LKP
Sbjct: 556 LGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKP 615
Query: 1576 NDALVYNFRAKVRGKIGLIEEAMADYNQALDL 1607
+L +N + G + +A A +AL+L
Sbjct: 616 EHSLAWNNMIILLDNTGNLAQAEAVGREALEL 647
>gi|118766330 transmembrane and tetratricopeptide repeat containing 4
isoform 1 [Homo sapiens]
Length = 760
Score = 71.2 bits (173), Expect = 7e-12
Identities = 66/294 (22%), Positives = 130/294 (44%), Gaps = 4/294 (1%)
Query: 1304 GSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKD 1363
G L T C R E+ F AL + P + G + + G+ A A +
Sbjct: 467 GILFINTLRCVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTA---AIRY 523
Query: 1364 FLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMG 1423
+ +A+ +NP Y+ A + G L+ + + Q+A ++A+ P A+ +V +
Sbjct: 524 YREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLK 583
Query: 1424 NNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNA 1482
AA Q A+K + N G ++ + +A+ +++A L P++SLA+ N
Sbjct: 584 RFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNM 643
Query: 1483 GNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPF 1542
+ + +QA +AL+ P + ++ + A +KY+E++ F I++ P
Sbjct: 644 IILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPN 703
Query: 1543 WAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEE 1596
A+ + N A Y+ +LA++ +L L P + +R K+ L+++
Sbjct: 704 AASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRRKLELMQK 757
Score = 70.1 bits (170), Expect = 2e-11
Identities = 43/152 (28%), Positives = 73/152 (48%)
Query: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN 1515
G++ A++ Y++A+ LNPKY A N GNI + +A + S A++ P+ MN
Sbjct: 515 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMN 574
Query: 1516 RAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKP 1575
I LK++E A++ + I+ + Y+N Y L ++ A A LKP
Sbjct: 575 LGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKP 634
Query: 1576 NDALVYNFRAKVRGKIGLIEEAMADYNQALDL 1607
+L +N + G + +A A +AL+L
Sbjct: 635 EHSLAWNNMIILLDNTGNLAQAEAVGREALEL 666
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 70.1 bits (170), Expect = 2e-11
Identities = 74/310 (23%), Positives = 136/310 (43%), Gaps = 19/310 (6%)
Query: 1283 LGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYV 1342
LG++ A+E + +AA +++ + + H +C+ + +F +A + AL +N L Y+
Sbjct: 114 LGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDL-TYI 172
Query: 1343 GRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAI 1402
G ++ G + + K KA+ +P + + G G +QKA+ H A+
Sbjct: 173 MLGKIHLLEGDLDKAIEVYK---KAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNAL 229
Query: 1403 DTDPKNYLAYEGRAVVCLQMGNNFAAMQDINA-AMKISTTAEFLTNRGVIHEFMGHKQN- 1460
DP NY A + G+ A+ A + + N G+ F G K+
Sbjct: 230 TYDPTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMC--FFGKKKYV 287
Query: 1461 -AMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAIT 1519
A+ + A L P +N G ++ +Q++ A + S A+ F P+ + M A+
Sbjct: 288 AAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVA 347
Query: 1520 NTILKKYEEAKEDFANVI--ESC-PF----WAAVYFNRAHFYYCLKQYELAEEDLNKALS 1572
T L+ E AK +A + + C P +A + +N+ L QY+ E+ K
Sbjct: 348 LTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEK---KVSL 404
Query: 1573 LKPNDALVYN 1582
LK N +L ++
Sbjct: 405 LKDNSSLEFD 414
Score = 50.8 bits (120), Expect = 1e-05
Identities = 59/257 (22%), Positives = 107/257 (41%), Gaps = 13/257 (5%)
Query: 1353 HDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAY 1412
++EA K QKD+ + ++ YI + +F KA + A++ + ++ L Y
Sbjct: 124 YNEAAKLNQKDWEISHNLGVCYIYLK-----------QFNKAQDQLHNALNLN-RHDLTY 171
Query: 1413 EGRAVVCLQMGNNFAAMQDINAAMKIST-TAEFLTNRGVIHEFMGHKQNAMKDYQDAITL 1471
+ L G+ A++ A++ S E LT G+++ +G Q A + +A+T
Sbjct: 172 IMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTY 231
Query: 1472 NPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKE 1531
+P A AG++ H F A + PE+ + N + KKY A
Sbjct: 232 DPTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAIS 291
Query: 1532 DFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKI 1591
PF + +N + ++QY A L+ A++ +P +Y A +
Sbjct: 292 CLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNL 351
Query: 1592 GLIEEAMADYNQALDLE 1608
IE A Y +A+ L+
Sbjct: 352 EDIENAKRAYAEAVHLD 368
Score = 48.1 bits (113), Expect = 7e-05
Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Query: 1374 YIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDIN 1433
Y++A I + +G Q++ F P++ + A +G + AA++ N
Sbjct: 71 YVQALI-----FRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYN 125
Query: 1434 AAMKISTTA-EFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQF 1492
A K++ E N GV + ++ A +A+ LN ++ L Y G I+
Sbjct: 126 EAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLN-RHDLTYIMLGKIHLLEGDL 184
Query: 1493 SQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCP 1541
+A + + KA++F PEN +L + L Y++A E N + P
Sbjct: 185 DKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDP 233
Score = 43.1 bits (100), Expect = 0.002
Identities = 81/376 (21%), Positives = 146/376 (38%), Gaps = 29/376 (7%)
Query: 1097 KYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCAL 1156
K Y+ K I + + +GL E + QALI+ N +++E+ CA+
Sbjct: 46 KDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQ----------TCAV 95
Query: 1157 LAKVQM-KAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTY 1215
L+ K+ ++ +L K AI ++ + +NLG+CY+ +
Sbjct: 96 LSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYI----YLKQF 151
Query: 1216 KLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFL- 1274
A L A++++++ T + KI L+ L D I + A E NT L
Sbjct: 152 NKAQDQLHNALNLNRHDLTY-----IMLGKIHLLEGDL-DKAIEVYKKAVEFSPENTELL 205
Query: 1275 -NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKI 1333
GL+Y++LG Y A E A TN A +F+ A+ + ++
Sbjct: 206 TTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKY----RV 261
Query: 1334 NPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQ 1392
C + N+ M + + A +A ++ P K + G ++
Sbjct: 262 VACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYA 321
Query: 1393 KAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLT-NRGVI 1451
A++ + AI+ PK Y AV + + A + A+ + + N V+
Sbjct: 322 SAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVL 381
Query: 1452 HEFMGHKQNAMKDYQD 1467
G K+NA+ YQ+
Sbjct: 382 LYNQGEKKNALAQYQE 397
Score = 35.8 bits (81), Expect = 0.34
Identities = 83/419 (19%), Positives = 144/419 (34%), Gaps = 61/419 (14%)
Query: 896 KYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYW 955
K YE+ ++ E++ + +A + I+R G +Q ++ Q +L P +
Sbjct: 46 KDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLK 105
Query: 956 HRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKST 1015
K A++ N K N+ + E + Y K A A+
Sbjct: 106 QVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLN 165
Query: 1016 PTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIED 1074
D Y G+++ + + AI+ + K + + P+ T+ L GL Y + + A E
Sbjct: 166 RHDL-TYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEH 224
Query: 1075 FTALLNIDHQNSQ---ARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFC 1131
L D N + A G + +D+A T Y++ + E P+
Sbjct: 225 LGNALTYDPTNYKAILAAGSMMQTHGDFDVA-LTKYRVVAC--AVPESPPL--------- 272
Query: 1132 ENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDAT 1191
WN M KK + AIS +
Sbjct: 273 --------------WNNIGMCFFG------------------KKKYVAAISCLKRANYLA 300
Query: 1192 AISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQM 1251
LYNLGL ++ Y A L+ AI+ + A+ T + +++
Sbjct: 301 PFDWKILYNLGLVHL----TMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIEN 356
Query: 1252 ALTDYGIVLLLD-ATETVKLN---TFLNRGLIYVELGQYGFALEDFKQAALISRTNGSL 1306
A Y + LD V LN N+G L QY ++ ++ + + N SL
Sbjct: 357 AKRAYAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQY----QEMEKKVSLLKDNSSL 411
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 68.9 bits (167), Expect = 4e-11
Identities = 56/241 (23%), Positives = 99/241 (41%), Gaps = 7/241 (2%)
Query: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMG-----NNFAAMQDIN 1433
++ Y L G + +A HF+ + +P A GR + + G N A+ +++
Sbjct: 147 LAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELS 206
Query: 1434 AAMKISTTA-EFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQF 1492
+ + E R I +G A+ D AI L P L Y + G +YF +
Sbjct: 207 RVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDY 265
Query: 1493 SQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAH 1552
+ A + F ++L+ + ++ + +T +EA E F ++ + Y +
Sbjct: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325
Query: 1553 FYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYAS 1612
Y L +E A E KAL L N R + G ++EA+ ++ + L LE Y
Sbjct: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNE 385
Query: 1613 V 1613
V
Sbjct: 386 V 386
Score = 68.2 bits (165), Expect = 6e-11
Identities = 55/234 (23%), Positives = 105/234 (44%), Gaps = 8/234 (3%)
Query: 1198 LYNLGLCYMEEGNLQM-TYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDY 1256
+Y G+ Y ++G + +LA+ +L+ I+++ + F RA + + + A+ D
Sbjct: 180 IYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDL 239
Query: 1257 GIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHR 1316
+ L + + + +RG +Y Y A EDF+Q+ +++ +
Sbjct: 240 TKAIQLQPSARL----YRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFH 295
Query: 1317 INEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIK 1376
+EA+ F ALK F+DAY G +Y E G+ EA A + F KAL +N +++
Sbjct: 296 RGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEA---ATESFQKALLLNQNHVQ 352
Query: 1377 ARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQ 1430
G L G Q+A +F + +P N + + + + MG + ++
Sbjct: 353 TLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIK 406
Score = 62.0 bits (149), Expect = 4e-09
Identities = 51/205 (24%), Positives = 90/205 (43%), Gaps = 4/205 (1%)
Query: 922 RRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYN 981
+R I LG++ A+NDL + I L+P Y HR +Y + A +D + N
Sbjct: 221 QRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELN 279
Query: 982 KNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMY-EITNKVLAIDD 1040
KN A L K + + + AI ++ +A+K D Y G+ Y E+ N A +
Sbjct: 280 KNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATES 339
Query: 1041 FSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYD 1100
F K + + L RG+ + + A+++F L ++ N QY+ + +
Sbjct: 340 FQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVC--QYMKGLSHVA 397
Query: 1101 LAKFTIYQIAEMDKGLSELSPMQQA 1125
+ +F A+ L++ P Q+A
Sbjct: 398 MGQFYEGIKAQTKVMLNDPLPGQKA 422
Score = 49.7 bits (117), Expect = 2e-05
Identities = 70/299 (23%), Positives = 116/299 (38%), Gaps = 47/299 (15%)
Query: 1215 YKLAITDLTTAISMDKNSYTAFYNRALCYTK-----IRELQMALTDYGIVLLLDATETVK 1269
Y AI +T + + + +A Y R + Y K I+ ++AL + V+ L+
Sbjct: 159 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRP-- 216
Query: 1270 LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTW 1329
E F+Q A I G RINE AVN T
Sbjct: 217 ---------------------EVFEQRAEILSPLG-----------RINE---AVNDLTK 241
Query: 1330 ALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQG 1389
A+++ P Y RG Y D AT A +DF ++L +N A + G +G
Sbjct: 242 AIQLQPS-ARLYRHRGTLYF-ISEDYAT--AHEDFQQSLELNKNQPIAMLYKGLTFFHRG 297
Query: 1390 KFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNR 1448
++A F A+ AY+ ++GN AA + A+ ++ + L R
Sbjct: 298 LLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLR 357
Query: 1449 GVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDP 1507
G++ G Q A+K+++ + L P + + G + QF + +K + DP
Sbjct: 358 GMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 416
Score = 47.4 bits (111), Expect = 1e-04
Identities = 55/245 (22%), Positives = 99/245 (40%), Gaps = 18/245 (7%)
Query: 886 VESDLPQEVIKYYESEVKILT------EEINDKTKY-----PAFAYCRRGAIYRKLGKLQ 934
+E D P+ +E +IL+ E +ND TK A Y RG +Y
Sbjct: 211 LEPDRPE----VFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYA 266
Query: 935 SAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEI 994
+A D Q+ + L A ++ L + + + EA++ K + +AY S +
Sbjct: 267 TAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQA 326
Query: 995 YRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM-YEITNKVLAIDDFSKCIFYDPKRTD 1053
YR + A ++ +A+ RG M Y + A+ +F +C+ +P
Sbjct: 327 YRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEV 386
Query: 1054 ALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMD 1113
+GL + ++ I+ T ++ D Q L +KY L +++ Y A +D
Sbjct: 387 CQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKY--LREYSRYLHAHLD 444
Query: 1114 KGLSE 1118
L+E
Sbjct: 445 TPLTE 449
Score = 43.5 bits (101), Expect = 0.002
Identities = 47/246 (19%), Positives = 95/246 (38%), Gaps = 38/246 (15%)
Query: 1320 FEEAVNFFTWALKINPCFLDAYVGRGNSYMEYG-HD-EATKQAQKDFLKALHINPAYIKA 1377
++EA+ F+ L+ P + A GRG +Y + G HD + + A + + + + P +
Sbjct: 159 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEV 218
Query: 1378 RISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMK 1437
L G+ +A N T AI P L Y R + + A +D +++
Sbjct: 219 FEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDYATAHEDFQQSLE 277
Query: 1438 ISTTAEFLT--------NRGVIHEF---------------------------MGHKQNAM 1462
++ +RG++ E +G+ + A
Sbjct: 278 LNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAAT 337
Query: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
+ +Q A+ LN + G + +HH +A F + L+ +P NE + +++
Sbjct: 338 ESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVA 397
Query: 1523 LKKYEE 1528
+ ++ E
Sbjct: 398 MGQFYE 403
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 66.2 bits (160), Expect = 2e-10
Identities = 149/680 (21%), Positives = 277/680 (40%), Gaps = 92/680 (13%)
Query: 1000 DITLAILNYTQAIKSTPTDADIYFRRGEMY-EITNKVLAIDDFSKCIFYDPKRTDALLKR 1058
D AI+ Y +A+ P + +Y R Y +I A+DD K +PK A ++
Sbjct: 73 DFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFRQ 132
Query: 1059 GLFYCENENWFAAIEDFTALLNIDHQNSQAR-GQYLLMMK--YYDLAKFTIYQIAEMDKG 1115
G+ A+ F + L D ++ Q G MK D + T Q+ +M
Sbjct: 133 GVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDSLEPTYQQLQKMKLD 192
Query: 1116 LSE---LSPMQQALIYSFCENHDKAIEVLD-----GISWNRAEMTMCALLAKVQMKAKRT 1167
S +S + Q L+ + +H ++ VL+ G + ++ + L+ T
Sbjct: 193 KSPFVVVSVVGQELLTA--GHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAYWSLGNT 250
Query: 1168 KEAVEVLKKALD-AISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITD----- 1221
+++ +++ LD A + D+ + A NLG + +GN Y+ A+T+
Sbjct: 251 EKSTGYMQQDLDVAKTLGDQTGECRAHG-----NLGSAFFSKGN----YREALTNHRHQL 301
Query: 1222 -LTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLL---DATETVKLNTFLNRG 1277
L + + + +A + YT I + AL + +LL E + N G
Sbjct: 302 VLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMG 361
Query: 1278 LIYVELGQYGFALEDFKQAALISRTNG-------SLCHATAMCHHRINEFEEAVNFFTWA 1330
+Y+ +G + A++ +Q I++ G + + + H+R N F++A+++ +
Sbjct: 362 AVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYRRN-FDKAMSYHNYV 420
Query: 1331 LKINPCFLD------AYVGRGNSYMEYGHDEATKQ---AQKDFLKALHINPAYIKARISF 1381
L++ ++ AY G G++ E KQ Q + L A +A +
Sbjct: 421 LELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNL 480
Query: 1382 GYNLQAQGKFQKAWN-HFT-IAIDTDPKNYLAYEGRAVVCLQMGNNFAAM---------- 1429
G Q +G + A H T + I + +Y A +GRA MGN + A+
Sbjct: 481 GIIHQMKGDYDTALKLHKTHLCIAQELSDYAA-QGRAYG--NMGNAYNALGMYDQAVKYH 537
Query: 1430 -QDINAAMKISTTAEFLTNRG---VIHEFMGHKQNAMKDYQDAITLNPKY------SLAY 1479
Q++ +M+++ A + G V ++ +G A++ YQ+ + + + + A
Sbjct: 538 RQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARAL 597
Query: 1480 FNAGNIYFHHRQFSQASDYFSKALKFDPENE------YVLMNRAITNTILKKYEEAKEDF 1533
N GN + ++ QA+ Y+ + L+ P+ + V N + L Y+EA + +
Sbjct: 598 SNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYY 657
Query: 1534 ------ANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKV 1587
A + A Y N + L + AEE LSL + + N +AK
Sbjct: 658 EQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQS---LNNSQAKF 714
Query: 1588 R--GKIGLIEEAMADYNQAL 1605
R G +G I D N A+
Sbjct: 715 RALGNLGDIFICKKDINGAI 734
Score = 40.8 bits (94), Expect = 0.011
Identities = 104/464 (22%), Positives = 175/464 (37%), Gaps = 86/464 (18%)
Query: 1200 NLGLCYMEEGNLQMTYKLAITDLTTAISMDK------------NSYTAF--YNRALCYTK 1245
NLG+ + +G+ KL T L A + N+Y A Y++A+ Y +
Sbjct: 479 NLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHR 538
Query: 1246 IRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGS 1305
+ELQ+++ + +T N + Y LG + AL+ ++ I+R
Sbjct: 539 -QELQISMEVND--------RASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRD 589
Query: 1306 L-CHATAMC-----HHRINEFEEAVNFFTWALKINPCFLDAYVGRGN-----SYMEY--- 1351
+ A A+ H E+ +A ++ L++ P D G G Y Y
Sbjct: 590 IQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDME-GEGKVCHNLGYAHYCLG 648
Query: 1352 GHDEATKQAQKDFL--KALHINPAYIKARISFGYNLQAQGKFQKA--WNHFTIAIDTDPK 1407
+ EA K ++D K LH + KA + G +A F KA + +++
Sbjct: 649 NYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLN 708
Query: 1408 NYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQD 1467
N A + RA+ +G+ F +DIN A+K + G+ H+ + A
Sbjct: 709 NSQA-KFRALG--NLGDIFICKKDINGAIKF-----YEQQLGLAHQVKDRRLEAS----- 755
Query: 1468 AITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENE-------------YVLM 1514
AY G Y +++ +A Y ++ L+ E V M
Sbjct: 756 ----------AYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYM 805
Query: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA----EEDLNKA 1570
K YEE + D ++ A VY N + E A E+ L
Sbjct: 806 ALGKYTMAFKCYEE-QLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAML 864
Query: 1571 LSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALD-LEDYASV 1613
L N++++ R + G +G EA+ DY +A+ E Y SV
Sbjct: 865 QQLSGNESVLD--RGRAYGNLGDCYEALGDYEEAIKYYEQYLSV 906
Score = 39.7 bits (91), Expect = 0.024
Identities = 66/313 (21%), Positives = 113/313 (36%), Gaps = 73/313 (23%)
Query: 1330 ALKINPCFL----DAYVGRGNSYMEYGHDEATK---QAQKDFLKALHINPAYIKARISFG 1382
ALKI C L + ++Y G+ E + Q D K L +A + G
Sbjct: 222 ALKIGTCSLKLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLG 281
Query: 1383 YNLQAQGKFQKAW-NH---FTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI 1438
++G +++A NH +A+ + E + +G+ + A+ D A+
Sbjct: 282 SAFFSKGNYREALTNHRHQLVLAMKLKDR-----EAASSALSSLGHVYTAIGDYPNALAS 336
Query: 1439 S--------------TTAEFLTNRGVIHEFMGHKQNAMKDYQDAITL------NPKYSLA 1478
+ A L N G ++ MG +NA++ ++ + + + + A
Sbjct: 337 HKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARA 396
Query: 1479 YFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIE 1538
Y N G+ Y + R F +A Y + L+ E LM +AI
Sbjct: 397 YSNLGSAYHYRRNFDKAMSYHNYVLELAQE----LMEKAIE------------------- 433
Query: 1539 SCPFWAAVYFNRAHFYYCLKQYELA----EEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594
Y H C++ E A E+ L A LK A + +G+I
Sbjct: 434 -----MRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAA-----EGRASSNLGII 483
Query: 1595 EEAMADYNQALDL 1607
+ DY+ AL L
Sbjct: 484 HQMKGDYDTALKL 496
Score = 38.1 bits (87), Expect = 0.069
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Query: 1313 CHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372
CH +F A+ + AL ++P Y R +YM+ + +A D +KA +NP
Sbjct: 69 CHD--GDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKI---QQYDKALDDAIKARLLNP 123
Query: 1373 AYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKN 1408
+ KA G LQ G+ A F + DPK+
Sbjct: 124 KWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKS 159
Score = 36.6 bits (83), Expect = 0.20
Identities = 127/625 (20%), Positives = 216/625 (34%), Gaps = 145/625 (23%)
Query: 892 QEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFL 951
QE +KYYE ++ L ++++DK A AYC G ++ L A
Sbjct: 651 QEAVKYYEQDL-ALAKDLHDKLS-QAKAYCNLGLAFKALLNFSKAEE------------- 695
Query: 952 NAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQ- 1010
++L+ L Q N ++ A + +I+ KKDI AI Y Q
Sbjct: 696 ---CQKYLLSLAQSLNN------------SQAKFRALGNLGDIFICKKDINGAIKFYEQQ 740
Query: 1011 -----AIKSTPTDADIYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLF--YC 1063
+K +A Y G Y + K + K + Y + + + C
Sbjct: 741 LGLAHQVKDRRLEASAYAALGTAYRMIQK------YDKALGYHTQELEVYQELSDLPGEC 794
Query: 1064 ENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQ 1123
AA+ A G+Y + K Y+ ++D G P
Sbjct: 795 RAHGHLAAV-------------YMALGKYTMAFKCYE---------EQLDLGQKLKDPSL 832
Query: 1124 QALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISH 1183
+A +Y + +M +EA+ ++ L A+
Sbjct: 833 EAQVY--------------------------GNMGITKMNMNVMEEAIGYFEQQL-AMLQ 865
Query: 1184 SDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRAL-- 1241
G ++ NLG CY G+ + K L+ A S+++ A R L
Sbjct: 866 QLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGN 925
Query: 1242 CYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISR 1301
+ + LQ AL + L++ +L N+ Y ELG L +++QA
Sbjct: 926 GHRAMGSLQQALVCFEKRLVV----AHELGEAFNKAQAYGELGSLHSQLGNYEQA----- 976
Query: 1302 TNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYG-HDEATKQA 1360
I+ E +N +K DA G G Y + G +D A +
Sbjct: 977 ---------------ISCLERQLN-IARDMKDRALESDAACGLGGVYQQMGEYDTALQYH 1020
Query: 1361 QKDFLKALHINPAYIKARI--SFGYNLQAQGKFQKA----WNHFTIAIDTDPKNYLAYEG 1414
Q D A N + R + G ++ G F++A H +IA N LA
Sbjct: 1021 QLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQ---MNDLA--A 1075
Query: 1415 RAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPK 1474
+ V +G A+Q+ + A+ +L + E +G +++ K +
Sbjct: 1076 KTVSYSSLGRTHHALQNYSQAVM------YLQEGLRLAEQLGRREDEAK-------IRHG 1122
Query: 1475 YSLAYFNAGNIYFHHRQFSQASDYF 1499
L+ + +GN+ Q +AS F
Sbjct: 1123 LGLSLWASGNLEEAQHQLYRASALF 1147
Score = 33.5 bits (75), Expect = 1.7
Identities = 17/63 (26%), Positives = 30/63 (47%)
Query: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVY 1547
H F A +++AL DP+N + NR+ +++Y++A +D P W Y
Sbjct: 70 HDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAY 129
Query: 1548 FNR 1550
F +
Sbjct: 130 FRQ 132
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 62.4 bits (150), Expect = 3e-09
Identities = 87/386 (22%), Positives = 156/386 (40%), Gaps = 44/386 (11%)
Query: 1261 LLDATETVK-LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINE 1319
LLD E + TF +G Y Y A + +A + N S A +
Sbjct: 18 LLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGR 77
Query: 1320 FEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARI 1379
F EA+ +++++ F+ ++ G ++ G+ A A + F +AL ++ +A+
Sbjct: 78 FREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMA---ACRSFQRALELDHKNAQAQQ 134
Query: 1380 SFG-------YNLQAQGKFQKAWNHFTI-----AIDTDPKNYLAYEGRAVVCLQMGNNFA 1427
F Y A+ F+K + A++ P + ++ CL M +
Sbjct: 135 EFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH-RFKILKAECLAMLGRYP 193
Query: 1428 AMQDINAAM--KISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP---KYSLAYFNA 1482
Q + + + ST A+ L RG+ + + A++ + A+ + P K +A NA
Sbjct: 194 EAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNA 253
Query: 1483 ---------GNIYFHHRQFSQASDYFSKALKFDPEN----EYVLMNRAITNTILKKYEEA 1529
GN F + A + +++AL DP N + NR N+ L+K ++A
Sbjct: 254 KALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDA 313
Query: 1530 KEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKAL---SLKPNDALVYNFRAK 1586
ED N ++ + Y RA Y +QYE A D K K + L+ N + +
Sbjct: 314 IEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLE 373
Query: 1587 VRGKIGLIEEAMADYNQALDLEDYAS 1612
+R + DY + L ++ AS
Sbjct: 374 LR------KSKRKDYYKILGVDKNAS 393
Score = 53.9 bits (128), Expect = 1e-06
Identities = 81/356 (22%), Positives = 131/356 (36%), Gaps = 63/356 (17%)
Query: 969 EALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM 1028
E LDD + K E + + Y KKD A YT+AI P +A Y R
Sbjct: 17 ELLDD-----QEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAAT 71
Query: 1029 YEITNKVL-AIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQ 1087
+ + A+ D + + D L+ G + N AA F L +DH+N+Q
Sbjct: 72 LMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQ 131
Query: 1088 ARGQYL---LMMKYYDLAKFTIYQ------IAEMDKGLSELSPMQQ----------ALIY 1128
A+ ++ +M+Y +A+ + + MD+ L E +P A++
Sbjct: 132 AQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRAL-EFAPACHRFKILKAECLAMLG 190
Query: 1129 SFCENHDKAIEVLDGISWNRAEMTMCAL-LAKVQMKAKRTKEAVEVLKKALDAISHSDKG 1187
+ E A ++L S N + + L L K + V+ L+ A D
Sbjct: 191 RYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIAC 250
Query: 1188 PDATAISADCLYNLGLCYMEEGNLQMTYKL------------------------------ 1217
+A A+ A G +EGN ++ Y+L
Sbjct: 251 RNAKALKAK--KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLR 308
Query: 1218 ----AITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVK 1269
AI D T A+ +D A+ RA CY + + A+ DY V + T+ K
Sbjct: 309 KLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHK 364
Score = 45.4 bits (106), Expect = 4e-04
Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 898 YESEVKILTEEIN---DKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAY 954
Y+ ++ TE + + K A YC RG + KL KL A+ D + L+ ++ AY
Sbjct: 272 YKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAY 331
Query: 955 WHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSK 991
R Y+ ++ EA+ D +++ K L K
Sbjct: 332 LRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLK 368
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 61.2 bits (147), Expect = 8e-09
Identities = 62/268 (23%), Positives = 110/268 (41%), Gaps = 14/268 (5%)
Query: 1355 EATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEG 1414
E+ Q + +H++ G QGK+ +A + +T +D DP N +
Sbjct: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTN 172
Query: 1415 RAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP 1473
RA ++ A D N A+ ++ + + + RG + + A KDY+ + L P
Sbjct: 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232
Query: 1474 ----------KYSLAYFNAGNIYFHHRQFS-QASDYFSKALKFDPENEYVLMNRAITNTI 1522
K S A + N Y ++++ K ++ + + + N
Sbjct: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292
Query: 1523 LK--KYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALV 1580
K KYE A E + I + A + NRA Y +++YE AE+D +A+ L + +
Sbjct: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352
Query: 1581 YNFRAKVRGKIGLIEEAMADYNQALDLE 1608
+ R R +G + EA D+ L LE
Sbjct: 353 FARRGTARTFLGKLNEAKQDFETVLLLE 380
Score = 58.9 bits (141), Expect = 4e-08
Identities = 35/120 (29%), Positives = 59/120 (49%)
Query: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548
H SQ S+ + D + VL + KY+EA + + +++ P+ +
Sbjct: 112 HESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT 171
Query: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
NRA Y+ LK++ +AE D N A++L + Y+ R R + +EEA DY + L+LE
Sbjct: 172 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 231
Score = 42.4 bits (98), Expect = 0.004
Identities = 66/292 (22%), Positives = 116/292 (39%), Gaps = 61/292 (20%)
Query: 1022 YFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNI 1081
YF++G+ E AID ++K + DP R Y + + A D + +
Sbjct: 143 YFKQGKYDE------AIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVAL 196
Query: 1082 DHQNSQA---RGQYLLMMKYYDLAKFTIYQIAEMD----KGLSELSPMQQALIY---SFC 1131
+ ++A RG ++ + AK ++ E++ + +EL + QAL S+
Sbjct: 197 NRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYP 256
Query: 1132 ENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDAT 1191
+ D I+ +G + Q++A++ K+ AIS D+G
Sbjct: 257 KEADIVIKSTEG--------------ERKQIEAQQNKQ---------QAISEKDRGNG-- 291
Query: 1192 AISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQM 1251
+ +EG Y+ AI T I+ D + NRA+ Y KI++ +
Sbjct: 292 -------------FFKEGK----YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334
Query: 1252 ALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTN 1303
A D +LLD + + F RG LG+ A +DF+ L+ N
Sbjct: 335 AEKDCTQAILLDGSYS---KAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383
Score = 38.5 bits (88), Expect = 0.053
Identities = 57/220 (25%), Positives = 96/220 (43%), Gaps = 35/220 (15%)
Query: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978
AY RRGA L KL+ A D +RV+ LEP N + EA ++L I
Sbjct: 203 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 245
Query: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034
+ + +Y +A+I G++ A N QAI S + +F+ G+ YE
Sbjct: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 299
Query: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA---RGQ 1091
AI+ +++ I D R + Y + + + A +D T + +D S+A RG
Sbjct: 300 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGT 358
Query: 1092 YLLMMKYYDLAKFTIYQIAEMDKG----LSELSPMQQALI 1127
+ + AK + ++ G ++ELS +++ LI
Sbjct: 359 ARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELI 398
Score = 34.7 bits (78), Expect = 0.77
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334
+RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++
Sbjct: 287 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346
Query: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372
+ A+ RG + G +A++DF L + P
Sbjct: 347 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 381
Score = 34.3 bits (77), Expect = 1.0
Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948
I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP
Sbjct: 329 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 381
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 60.1 bits (144), Expect = 2e-08
Identities = 56/227 (24%), Positives = 91/227 (40%), Gaps = 16/227 (7%)
Query: 1387 AQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLT 1446
+Q K F A D D N E A+ + +G+ A ST + L+
Sbjct: 123 SQAKSIAEQKRFPFATDNDSTN----EELAIAYVLIGSGLYD----EAIRHFSTMLQILS 174
Query: 1447 NRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFD 1506
G I+E A+ D AI L P L Y + G +YF ++ A + F ++L+ +
Sbjct: 175 PLGRINE-------AVNDLTKAIQLQPSARL-YRHRGTLYFISEDYATAHEDFQQSLELN 226
Query: 1507 PENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEED 1566
++ + +T +EA E F ++ + Y + Y L +E A E
Sbjct: 227 KNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATES 286
Query: 1567 LNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASV 1613
KAL L N R + G ++EA+ ++ + L LE Y V
Sbjct: 287 FQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEV 333
Score = 60.1 bits (144), Expect = 2e-08
Identities = 50/201 (24%), Positives = 88/201 (43%), Gaps = 4/201 (1%)
Query: 926 IYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNT 985
I LG++ A+NDL + I L+P Y HR +Y + A +D + NKN
Sbjct: 172 ILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQP 230
Query: 986 EAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMY-EITNKVLAIDDFSKC 1044
A L K + + + AI ++ +A+K D Y G+ Y E+ N A + F K
Sbjct: 231 IAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKA 290
Query: 1045 IFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKF 1104
+ + L RG+ + + A+++F L ++ N QY+ + + + +F
Sbjct: 291 LLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVC--QYMKGLSHVAMGQF 348
Query: 1105 TIYQIAEMDKGLSELSPMQQA 1125
A+ L++ P Q+A
Sbjct: 349 YEGIKAQTKVMLNDPLPGQKA 369
Score = 58.5 bits (140), Expect = 5e-08
Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
Query: 1263 DATETVKLNT----FLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRIN 1318
D T+ ++L + +RG +Y Y A EDF+Q+ +++ +
Sbjct: 185 DLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRG 244
Query: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
+EA+ F ALK F+DAY G +Y E G+ EA A + F KAL +N +++
Sbjct: 245 LLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEA---ATESFQKALLLNQNHVQTL 301
Query: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQ 1430
G L G Q+A +F + +P N + + + + MG + ++
Sbjct: 302 QLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIK 353
Score = 51.6 bits (122), Expect = 6e-06
Identities = 55/245 (22%), Positives = 102/245 (41%), Gaps = 14/245 (5%)
Query: 886 VESDLPQEVIKYYESEVKILT------EEINDKTKY-----PAFAYCRRGAIYRKLGKLQ 934
+ S L E I+++ + ++IL+ E +ND TK A Y RG +Y
Sbjct: 154 IGSGLYDEAIRHFSTMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYA 213
Query: 935 SAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEI 994
+A D Q+ + L A ++ L + + + EA++ K + +AY S +
Sbjct: 214 TAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQA 273
Query: 995 YRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM-YEITNKVLAIDDFSKCIFYDPKRTD 1053
YR + A ++ +A+ RG M Y + A+ +F +C+ +P
Sbjct: 274 YRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEV 333
Query: 1054 ALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMD 1113
+GL + ++ I+ T ++ D Q L +KY L +++ Y A +D
Sbjct: 334 CQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKY--LREYSRYLHAHLD 391
Query: 1114 KGLSE 1118
L+E
Sbjct: 392 TPLTE 396
Score = 47.4 bits (111), Expect = 1e-04
Identities = 60/245 (24%), Positives = 97/245 (39%), Gaps = 19/245 (7%)
Query: 1264 ATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEA 1323
AT+ N L + + G Y A+ F I G RINE A
Sbjct: 137 ATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLG-----------RINE---A 182
Query: 1324 VNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383
VN T A+++ P Y RG Y D AT A +DF ++L +N A + G
Sbjct: 183 VNDLTKAIQLQPS-ARLYRHRGTLYF-ISEDYAT--AHEDFQQSLELNKNQPIAMLYKGL 238
Query: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-A 1442
+G ++A F A+ AY+ ++GN AA + A+ ++
Sbjct: 239 TFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHV 298
Query: 1443 EFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKA 1502
+ L RG++ G Q A+K+++ + L P + + G + QF + +K
Sbjct: 299 QTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKV 358
Query: 1503 LKFDP 1507
+ DP
Sbjct: 359 MLNDP 363
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 60.1 bits (144), Expect = 2e-08
Identities = 67/305 (21%), Positives = 119/305 (39%), Gaps = 41/305 (13%)
Query: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
EEA+ ++K P F DAY + E E K+A++ + + P +
Sbjct: 457 EEAITLLKDSIKYGPEFADAYSSLASLLAE---QERFKEAEEIYQTGIKNCPDSSDLHNN 513
Query: 1381 FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIST 1440
+G L G +KA H+ AI P +++A + +G N A + A++++
Sbjct: 514 YGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAH 573
Query: 1441 TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP-----KYSLA----------------- 1478
AE L+ G ++ G + A++ YQ+A L P + +LA
Sbjct: 574 KAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTN 633
Query: 1479 ------------YFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAIT--NTILK 1524
Y IY +A D KAL+ P++ V+ T N + +
Sbjct: 634 HIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLRE 693
Query: 1525 K--YEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582
+ ++A E + ++ P A + N + +Y A +AL L P+ L+
Sbjct: 694 QNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKE 753
Query: 1583 FRAKV 1587
AK+
Sbjct: 754 NLAKL 758
Score = 55.5 bits (132), Expect = 4e-07
Identities = 66/325 (20%), Positives = 130/325 (40%), Gaps = 44/325 (13%)
Query: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
+EA+ + ALK+ P A G + T +A+ + +AL ++P + +A +
Sbjct: 392 KEAIYHYRTALKLYPRHASALNNLGTLTRD------TAEAKMYYQRALQLHPQHNRALFN 445
Query: 1381 FGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMK-IS 1439
G L++Q K ++A +I P+ AY A + + A + +K
Sbjct: 446 LGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCP 505
Query: 1440 TTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYF 1499
+++ N GV G + A+ YQ AI L+P + +A N G +Y + S A +++
Sbjct: 506 DSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWY 565
Query: 1500 SKALK---------------------------------FDPENEYVLMNRAITNTILKKY 1526
+AL+ P + + A ++ +
Sbjct: 566 KRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQT 625
Query: 1527 EEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAK 1586
+EA++ +++ Y + Y + ++ A + ++KAL LKP D V +
Sbjct: 626 KEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFF 685
Query: 1587 VRG----KIGLIEEAMADYNQALDL 1607
+G + L+++A Y A+ L
Sbjct: 686 TKGNQLREQNLLDKAFESYRVAVQL 710
Score = 53.9 bits (128), Expect = 1e-06
Identities = 51/220 (23%), Positives = 93/220 (42%), Gaps = 8/220 (3%)
Query: 1398 FTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMG 1456
F + T P N + A G N A+ A+K+ A L N G +
Sbjct: 364 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTR--- 420
Query: 1457 HKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNR 1516
A YQ A+ L+P+++ A FN GN+ + +A ++K+ PE +
Sbjct: 421 DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSL 480
Query: 1517 AITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPN 1576
A ++++EA+E + I++CP + ++ N F E A +A+ L P+
Sbjct: 481 ASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPS 540
Query: 1577 DALVYNFRAKVRGKIGLIEEAMAD--YNQALDLEDYASVI 1614
+ ++ +G E +MA+ Y +AL + A ++
Sbjct: 541 HHVAMVNLGRLYRSLG--ENSMAEEWYKRALQVAHKAEIL 578
Score = 53.9 bits (128), Expect = 1e-06
Identities = 55/283 (19%), Positives = 109/283 (38%), Gaps = 42/283 (14%)
Query: 1291 EDFKQAALISRTNGSLCHATAMCHHRINEF-------EEAVNFFTWALKINPCFLDAYVG 1343
E FK+A I +T C ++ H+ F E+AV + A+K++P A V
Sbjct: 488 ERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVN 547
Query: 1344 RGNSYMEYGHDEATKQAQKDFLKALH------------------------------INPA 1373
G Y G + ++ K L+ H + P+
Sbjct: 548 LGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPS 607
Query: 1374 YIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDIN 1433
+ R++ L G+ ++A + + Y + + + N+ A+ I+
Sbjct: 608 QRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAID 667
Query: 1434 AAMKIS-----TTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFH 1488
A+++ +E +G A + Y+ A+ LNP + A+ N G I
Sbjct: 668 KALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHI 727
Query: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKE 1531
++ A Y+ +AL+ P+++ + N A + + K+ +E +E
Sbjct: 728 KGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 770
Score = 38.1 bits (87), Expect = 0.069
Identities = 61/264 (23%), Positives = 92/264 (34%), Gaps = 42/264 (15%)
Query: 920 YCRRGAIYRKLGKLQ----SAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLN 975
Y R + LG L A QR + L P A ++ + Q+K EA+ L
Sbjct: 405 YPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLK 464
Query: 976 YIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITN-K 1034
KY +AY S A + ++ A Y IK+ P +D++ G T
Sbjct: 465 DSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLP 524
Query: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFY---CEN---ENWF------------------- 1069
A+ + + I P A++ G Y EN E W+
Sbjct: 525 EKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGAL 584
Query: 1070 -----------AAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMDKGLSE 1118
++ AL + A Q L +M A+ I + G E
Sbjct: 585 YYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLE 644
Query: 1119 LSPMQQALIYSFCENHDKAIEVLD 1142
+ A IYS ENHDKA++ +D
Sbjct: 645 CYRLLSA-IYSKQENHDKALDAID 667
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 58.9 bits (141), Expect = 4e-08
Identities = 35/120 (29%), Positives = 59/120 (49%)
Query: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548
H SQ S+ + D + VL + KY+EA + + +++ P+ +
Sbjct: 112 HESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT 171
Query: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
NRA Y+ LK++ +AE D N A++L + Y+ R R + +EEA DY + L+LE
Sbjct: 172 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 231
Score = 54.7 bits (130), Expect = 7e-07
Identities = 33/122 (27%), Positives = 58/122 (47%)
Query: 1466 QDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKK 1525
+D I ++ + +L GN YF ++ +A D ++K + DP N + NRA LKK
Sbjct: 123 EDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
Query: 1526 YEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRA 1585
+ A+ D + + Y R + L++ E A++D + L L+PN+ N
Sbjct: 183 FAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELR 242
Query: 1586 KV 1587
K+
Sbjct: 243 KI 244
Score = 53.1 bits (126), Expect = 2e-06
Identities = 57/305 (18%), Positives = 115/305 (37%), Gaps = 50/305 (16%)
Query: 1355 EATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEG 1414
E+ Q + +H++ G QGK+ +A + +T +D DP N +
Sbjct: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTN 172
Query: 1415 RAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP 1473
RA ++ A D N A+ ++ + + + RG + + A KDY+ + L P
Sbjct: 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232
Query: 1474 -----------------------------------------------KYSLAYFNAGNIY 1486
+ +++ + GN +
Sbjct: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292
Query: 1487 FHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAV 1546
F ++ +A + +++ + D N + NRA+ ++KYEEA++D I ++
Sbjct: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352
Query: 1547 YFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGK--IGLIEEAMADYNQA 1604
+ R L + A++D L L+P + +K++ K +I E + Q
Sbjct: 353 FARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQT 412
Query: 1605 LDLED 1609
+D+ D
Sbjct: 413 IDVPD 417
Score = 42.4 bits (98), Expect = 0.004
Identities = 66/292 (22%), Positives = 116/292 (39%), Gaps = 61/292 (20%)
Query: 1022 YFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNI 1081
YF++G+ E AID ++K + DP R Y + + A D + +
Sbjct: 143 YFKQGKYDE------AIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVAL 196
Query: 1082 DHQNSQA---RGQYLLMMKYYDLAKFTIYQIAEMD----KGLSELSPMQQALIY---SFC 1131
+ ++A RG ++ + AK ++ E++ + +EL + QAL S+
Sbjct: 197 NRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYP 256
Query: 1132 ENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDAT 1191
+ D I+ +G + Q++A++ K+ AIS D+G
Sbjct: 257 KEADIVIKSTEG--------------ERKQIEAQQNKQ---------QAISEKDRGNG-- 291
Query: 1192 AISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQM 1251
+ +EG Y+ AI T I+ D + NRA+ Y KI++ +
Sbjct: 292 -------------FFKEGK----YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334
Query: 1252 ALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTN 1303
A D +LLD + + F RG LG+ A +DF+ L+ N
Sbjct: 335 AEKDCTQAILLDGSYS---KAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383
Score = 36.6 bits (83), Expect = 0.20
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 28/174 (16%)
Query: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978
AY RRGA L KL+ A D +RV+ LEP N + EA ++L I
Sbjct: 203 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 245
Query: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034
+ + +Y +A+I G++ A N QAI S + +F+ G+ YE
Sbjct: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 299
Query: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA 1088
AI+ +++ I D R + Y + + + A +D T + +D S+A
Sbjct: 300 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352
Score = 34.7 bits (78), Expect = 0.77
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334
+RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++
Sbjct: 287 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346
Query: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372
+ A+ RG + G +A++DF L + P
Sbjct: 347 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 381
Score = 34.3 bits (77), Expect = 1.0
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Query: 923 RGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNK 982
R Y K+ K + A D + ILL+ + A+ R F K+NEA D +
Sbjct: 322 RAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP 381
Query: 983 NNTEAYLSKAEIYRGKKDITLAILNYT 1009
N +A ++I KK + I+ T
Sbjct: 382 GNKQAVTELSKI--KKKPLKKVIIEET 406
Score = 34.3 bits (77), Expect = 1.0
Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948
I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP
Sbjct: 329 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 381
>gi|224809432 transmembrane and tetratricopeptide repeat containing 3
[Homo sapiens]
Length = 914
Score = 58.5 bits (140), Expect = 5e-08
Identities = 76/387 (19%), Positives = 137/387 (35%), Gaps = 91/387 (23%)
Query: 1293 FKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYG 1352
F A +++ N L + FE A+ +F A + P + A++ G +Y
Sbjct: 435 FMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAHMNVGRTYKNLN 494
Query: 1353 HDEATKQAQKDFLKA--------------LHINPAYIKARISFGYNLQA-QGKFQKAWNH 1397
TK+A++ ++ A I P ++ I+ ++A + + ++A
Sbjct: 495 R---TKEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANESRLEEADQL 551
Query: 1398 FTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKIS-TTAEFLTNRGVIHEFMG 1456
+ AI P AY R + L+M A + A+++ A+ N ++H +
Sbjct: 552 YRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELK 611
Query: 1457 HKQNAMKDYQDAITLNPKYSLA-------------------------------------Y 1479
A+K++ A+ LNPK+ LA Y
Sbjct: 612 EPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLDANGY 671
Query: 1480 FNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRA--------------ITNTILKK 1525
FN G + ++ ++A + KA+K + L N A I +L+
Sbjct: 672 FNLGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNLALLYSQTAKELKALPILEELLRY 731
Query: 1526 YEE---------------------AKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAE 1564
Y + AK+ F ++E P N Y+ K AE
Sbjct: 732 YPDHIKGLILKGDILMNQKKDILGAKKCFERILEMDPSNVQGKHNLCVVYFEEKDLLKAE 791
Query: 1565 EDLNKALSLKPNDALVYNFRAKVRGKI 1591
L + L+L P++ + VR KI
Sbjct: 792 RCLLETLALAPHEEYIQRHLNIVRDKI 818
Score = 55.5 bits (132), Expect = 4e-07
Identities = 67/292 (22%), Positives = 121/292 (41%), Gaps = 25/292 (8%)
Query: 1293 FKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYG 1352
FK+ + I + L H+ HR ++E F ALK+N + G++
Sbjct: 402 FKKLSWICLSMVILTHSLKT-FHRNWDWESEYTLFMSALKVNKNNAKLWNNVGHALE--- 457
Query: 1353 HDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAY 1412
+++ ++A K FL+A H+ P I A ++ G + + ++A + +A P+
Sbjct: 458 NEKNFERALKYFLQATHVQPDDIGAHMNVGRTYKNLNRTKEAEESYMMAKSLMPQ----- 512
Query: 1413 EGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLN 1472
+ G +AA N ++ +I + A + Y+ AI++
Sbjct: 513 -------IIPGKKYAARIAPNHLNV------YINLANLIRANESRLEEADQLYRQAISMR 559
Query: 1473 PKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKED 1532
P + AY + G + + +A + + KAL+ D N + N AI + LK+ EA ++
Sbjct: 560 PDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKN 619
Query: 1533 FANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSL---KPNDALVY 1581
F +E P FN A + +L E + LS +P DA Y
Sbjct: 620 FNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLDANGY 671
Score = 43.9 bits (102), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 10/246 (4%)
Query: 1273 FLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALK 1332
+++RG + +++ + A E + +A + R N L + A+ H + E EA+ F AL+
Sbjct: 566 YISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALE 625
Query: 1333 INPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQ 1392
+NP A E G + +A+K L ++ P + G K
Sbjct: 626 LNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLDANGYFNLGMLAMDDKKDN 685
Query: 1393 KA--WNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMK-ISTTAEFLTNRG 1449
+A W I + D ++ A A++ Q A+ + ++ + L +G
Sbjct: 686 EAEIWMKKAIKLQADFRS--ALFNLALLYSQTAKELKALPILEELLRYYPDHIKGLILKG 743
Query: 1450 VIHEFMGHKQN---AMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFD 1506
I M K++ A K ++ + ++P N +YF + +A + L
Sbjct: 744 DI--LMNQKKDILGAKKCFERILEMDPSNVQGKHNLCVVYFEEKDLLKAERCLLETLALA 801
Query: 1507 PENEYV 1512
P EY+
Sbjct: 802 PHEEYI 807
Score = 39.3 bits (90), Expect = 0.031
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 20/192 (10%)
Query: 1434 AAMKIS-TTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQF 1492
+A+K++ A+ N G E + + A+K + A + P A+ N G Y + +
Sbjct: 437 SALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAHMNVGRTYKNLNRT 496
Query: 1493 SQASDYFSKALKFDPE----------------NEYV-LMNRAITNTILKKYEEAKEDFAN 1535
+A + + A P+ N Y+ L N N + EEA + +
Sbjct: 497 KEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANE--SRLEEADQLYRQ 554
Query: 1536 VIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIE 1595
I P + Y +R + + A+E KAL L N+A ++ A V ++
Sbjct: 555 AISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPN 614
Query: 1596 EAMADYNQALDL 1607
EA+ ++N+AL+L
Sbjct: 615 EALKNFNRALEL 626
Score = 32.3 bits (72), Expect = 3.8
Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 2/124 (1%)
Query: 976 YIHKYNKNNTEAYLSKAEIYRGKKD-ITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034
Y + N+ Y++ A + R + + A Y QAI P Y RGE+ NK
Sbjct: 519 YAARIAPNHLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNK 578
Query: 1035 VL-AIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYL 1093
L A + + K + D D + + E + A+++F L ++ ++ A
Sbjct: 579 PLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSA 638
Query: 1094 LMMK 1097
++M+
Sbjct: 639 IVMQ 642
>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
Length = 1564
Score = 56.2 bits (134), Expect = 2e-07
Identities = 89/388 (22%), Positives = 155/388 (39%), Gaps = 37/388 (9%)
Query: 1175 KKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTY-KLAITDLTTAISMDKN-- 1231
KK DA+ + +G + + Y+L E ++M K A+ + A+ + N
Sbjct: 286 KKYEDAVRNLTEGLKESPVCTSGWYHLA-----EAQVKMHRPKEAVLSCSQALKIVDNLG 340
Query: 1232 -SYTAFYNRALCYTKIRELQMALTDYG--------IVLLLDATETVKLNTFLNRGLIYVE 1282
S + Y R LC E + L+DY + + DA L + + L Y
Sbjct: 341 ASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISDADNIPGL--LVLKSLAYRN 398
Query: 1283 LGQYGFALEDFKQAALISRTNGSLCHAT-AMCHHRINEFEEAVNFFTWALKINPCFLDAY 1341
G + A + + L S + + HA A+ H ++ +A F AL+ + + +
Sbjct: 399 KGSFDEAAK-IMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYH 457
Query: 1342 VGRGNSYMEYGHD---EATKQAQKDFLKALHINPAYIKARISFGYNLQ--------AQGK 1390
G +Y G + + TK A FLKA ++ K G+ + A+G
Sbjct: 458 YQLGLTYWFMGEETRKDKTK-ALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGC 516
Query: 1391 FQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGV 1450
++KA+ DTD ++ A +V M A + + T RG+
Sbjct: 517 YRKAFE----LDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGL 572
Query: 1451 IHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENE 1510
+ G A+ D Q A+ +PK + + G Y ++ A F+KA + +PE+
Sbjct: 573 YYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESI 632
Query: 1511 YVLMNRAITNTILKKYEEAKEDFANVIE 1538
Y + A IL KY+EA + +I+
Sbjct: 633 YSVFKVAAIQQILGKYKEAVAQYQMIIK 660
Score = 38.5 bits (88), Expect = 0.053
Identities = 100/521 (19%), Positives = 187/521 (35%), Gaps = 82/521 (15%)
Query: 918 FAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYI 977
+A+ RRG Y K G+ A+ DLQ + +P N + YL + AL
Sbjct: 565 WAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKA 624
Query: 978 HKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKVLA 1037
+ N + + A I + A+ Y IK GE + + K
Sbjct: 625 SELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAAL 684
Query: 1038 IDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMK 1097
+D + D K D + K A+E FT L Q R + K
Sbjct: 685 VD------YLDGKAVDYIEK-------------ALEYFTCAL-------QHRADVSCLWK 718
Query: 1098 YYDLAKFTIYQIAEMDKGLSELSPM-----------QQALIYSFCENHDKAIEVLD---- 1142
A +Y +A + L + + L++ + +A++++
Sbjct: 719 LAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNT 778
Query: 1143 ----GISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCL 1198
GI++ R + + + + ++++ LKKA+ S++ +A + A
Sbjct: 779 WCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVA--- 835
Query: 1199 YNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGI 1258
CY GN Y LA +I ++ + A+ N + Y ++ A + +
Sbjct: 836 -----CYSGIGN----YALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKM 886
Query: 1259 VLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA-LISRTNGSLCHATAMCHHRI 1317
LD + L ++ + LI +G Y ++ F+ L T G+L +A +C
Sbjct: 887 AQSLDPS---YLMCWIGQALIAEAVGSYD-TMDLFRHTTELNMHTEGALGYAYWVCTTLQ 942
Query: 1318 NEFEEAVNFFTW------ALKINPCFLDAYVGRGNSYME--------YGHDEATKQAQKD 1363
++ + + A+ L+ YV R +Y H + K+A
Sbjct: 943 DKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANA 1002
Query: 1364 FLKALHI------NPAYIKARISFGYNLQAQGKFQKAWNHF 1398
+ +A+ + Y A ++G L + G++ KA F
Sbjct: 1003 YQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAF 1043
Score = 34.7 bits (78), Expect = 0.77
Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 3/137 (2%)
Query: 1213 MTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNT 1272
M LAI T + + A+ R L Y K + A+ D L D + N
Sbjct: 544 MEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKD---FNC 600
Query: 1273 FLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALK 1332
+ + G Y+ G Y AL+ F +A+ ++ + A + +++EAV + +K
Sbjct: 601 WESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIK 660
Query: 1333 INPCFLDAYVGRGNSYM 1349
++ A G G ++
Sbjct: 661 KKEDYVPALKGLGECHL 677
>gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens]
Length = 873
Score = 55.5 bits (132), Expect = 4e-07
Identities = 74/321 (23%), Positives = 134/321 (41%), Gaps = 34/321 (10%)
Query: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
++E AV F+ AL ++P +D Y R +Y++ + Q + N +++ R
Sbjct: 76 DWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLE-R 134
Query: 1379 ISFGYNLQAQGKFQK-----AWNHFTIAIDTDPKNYLAYEGRAVVC-LQMGNNFAAMQDI 1432
++F LQ Q F++ A N F+ A + P+ + R + C L + + A + I
Sbjct: 135 LTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEK-PCFRYRCMACLLALKQHQACLTLI 193
Query: 1433 NAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQ 1491
+K TT A+ R ++ F+ +D A+ LNPK+ A + +Q
Sbjct: 194 TNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQ 253
Query: 1492 FSQ-------------ASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIE 1538
Q A ++A++ +P + + + R L++++ A EDF V++
Sbjct: 254 ARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLD 313
Query: 1539 SCPFWAAVYFNRAH----------FYYCLKQ--YELAEEDLNKALSLKPNDALVYNFRAK 1586
+A +C +Q Y+ LNKAL + + +Y R
Sbjct: 314 MVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGD 373
Query: 1587 VRGKIGLIEEAMADYNQALDL 1607
++G + A ADY QAL L
Sbjct: 374 CFFQLGNLAFAEADYQQALAL 394
Score = 51.6 bits (122), Expect = 6e-06
Identities = 103/500 (20%), Positives = 181/500 (36%), Gaps = 101/500 (20%)
Query: 1049 PKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQ 1108
P + RG E +W A+ F+ L++D Q ++ +Y L Q
Sbjct: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQ----------LVDFYALRAEAYLQ 107
Query: 1109 IAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAE--MTMCALLAKVQMKAKR 1166
+ + L YS +++ K +E L + + + + CA L
Sbjct: 108 LCDFSSAAQNLRRA-----YSLQQDNCKHLERLTFVLYLQGQCLFEQCAFL--------- 153
Query: 1167 TKEAVEVLKKALDAISHS-DKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTA 1225
AL+ SH+ + P+ C+ C + ++ +T +T
Sbjct: 154 ---------DALNVFSHAAELQPEKPCFRYRCM----ACLLA----LKQHQACLTLITNE 196
Query: 1226 ISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQ 1285
+ D + + RA Y +++ + D LLL+ R L+ + Q
Sbjct: 197 LKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQA------RMLLQKMVAQ 250
Query: 1286 YGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRG 1345
+ +Q A I G L HA RIN A++ NP ++ RG
Sbjct: 251 ----AQQARQDAGILAVQGKLQHAL----QRINR----------AIENNPLDPSLFLFRG 292
Query: 1346 NSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTD 1405
Y + A +DFLK L + + + QAQ + +N F
Sbjct: 293 TMYRRLQEFDG---AVEDFLKVLDMVTEDQEDMVR-----QAQRQLLLTYNDF------- 337
Query: 1406 PKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKD 1464
AV C + G + +N A++ + L NRG +G+ A D
Sbjct: 338 ----------AVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEAD 387
Query: 1465 YQDAITLNP-------KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRA 1517
YQ A+ L+P + L G +QF +A ++FS A++ +P+ + RA
Sbjct: 388 YQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRA 447
Query: 1518 ITNTILKKYEEAKEDFANVI 1537
+ +L+ A++D A V+
Sbjct: 448 KSRQLLQNIFGARQDVATVL 467
Score = 50.1 bits (118), Expect = 2e-05
Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 22/186 (11%)
Query: 1273 FLNRGLIYVELGQYGFALEDF---------KQAALISRTNGSLC---HATAMCHHRINEF 1320
FL RG +Y L ++ A+EDF Q ++ + L + A+ +R +
Sbjct: 288 FLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAY 347
Query: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
+E V AL+ Y+ RG+ + + G+ A+ D+ +AL ++P A
Sbjct: 348 QEGVLLLNKALRDEQQEKGLYINRGDCFFQLGN---LAFAEADYQQALALSPQDEGANTR 404
Query: 1381 FGYNLQAQG-------KFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDIN 1433
G + G +FQKA NHF+ AI +P+ Y RA + N F A QD+
Sbjct: 405 MGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVA 464
Query: 1434 AAMKIS 1439
+ ++
Sbjct: 465 TVLLLN 470
Score = 38.1 bits (87), Expect = 0.069
Identities = 45/204 (22%), Positives = 71/204 (34%), Gaps = 26/204 (12%)
Query: 1372 PAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQD 1431
P ++ S G Q ++ A F+ A+ DP+ Y RA LQ+ + +A Q+
Sbjct: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQN 117
Query: 1432 INAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQ 1491
+ A + QD + + + G F
Sbjct: 118 LRRAYSLQ--------------------------QDNCKHLERLTFVLYLQGQCLFEQCA 151
Query: 1492 FSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRA 1551
F A + FS A + PE LK+++ N ++ A VY RA
Sbjct: 152 FLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRA 211
Query: 1552 HFYYCLKQYELAEEDLNKALSLKP 1575
Y L++ L DL+ AL L P
Sbjct: 212 RLYNFLQKPHLCYRDLHSALLLNP 235
Score = 37.4 bits (85), Expect = 0.12
Identities = 74/402 (18%), Positives = 144/402 (35%), Gaps = 50/402 (12%)
Query: 1212 QMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDY--GIVLLLDATETVK 1269
Q ++ A+ + A+ +D + RA Y ++ + A + L D + ++
Sbjct: 74 QADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLE 133
Query: 1270 LNTFLN--RGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFF 1327
TF+ +G E + AL F AA + + C + + + +
Sbjct: 134 RLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLI 193
Query: 1328 TWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYN--- 1384
T LK + D Y+ R Y + +D AL +NP + +AR+
Sbjct: 194 TNELKQDTTNADVYIFRARLY---NFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQ 250
Query: 1385 ----------LQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINA 1434
L QGK Q A AI+ +P + + L G + +Q+ +
Sbjct: 251 AQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLF-------LFRGTMYRRLQEFD- 302
Query: 1435 AMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHR-QFS 1493
G + +F+ +D +D + + L +N ++ + + +
Sbjct: 303 --------------GAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQ 348
Query: 1494 QASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFN---- 1549
+ +KAL+ + + + + +NR L A+ D+ + P
Sbjct: 349 EGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLL 408
Query: 1550 RAHFYYC---LKQYELAEEDLNKALSLKPNDALVYNFRAKVR 1588
+ +C KQ++ AE + A+ P A Y +RAK R
Sbjct: 409 QEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSR 450
Score = 32.7 bits (73), Expect = 2.9
Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 23/152 (15%)
Query: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAY 954
+K +++ + ++T E+ T A Y R +Y L K DL +LL P A
Sbjct: 183 LKQHQACLTLITNELKQDTTN-ADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQA- 240
Query: 955 WHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKS 1014
R L+ + +A D + +GK L +N +AI++
Sbjct: 241 --RMLLQKMVAQAQQARQDAGIL----------------AVQGKLQHALQRIN--RAIEN 280
Query: 1015 TPTDADIYFRRGEMYEITNKV-LAIDDFSKCI 1045
P D ++ RG MY + A++DF K +
Sbjct: 281 NPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVL 312
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 55.1 bits (131), Expect = 5e-07
Identities = 85/361 (23%), Positives = 138/361 (38%), Gaps = 57/361 (15%)
Query: 1275 NRGLIYVELGQYGFALEDFKQAALI--SRTNGSLCHATAMCHHRINEFEEAVNFFTWALK 1332
NR + LG++ AL D +Q+ + S G L CH + A F AL+
Sbjct: 11 NRAATLMMLGRFREALGDAQQSVRLDDSFVRGHL--REGKCHLSLGNAMAACRSFQRALE 68
Query: 1333 INPCFLDAY--VGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGK 1390
++ A N+ MEY T ++DF K + + + +
Sbjct: 69 LDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVV--------------FCMDRALE 114
Query: 1391 FQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGV 1450
F A + F I LA GR + ++ M ST A+ L RG+
Sbjct: 115 FAPACHRFKIL----KAECLAMLGRYPEAQSVASDILRMD--------STNADALYVRGL 162
Query: 1451 IHEFMGHKQNAMKDYQDAITLNP---KYSLAYFNA---------GNIYFHHRQFSQASDY 1498
+ + A++ + A+ + P K +A NA GN F + A +
Sbjct: 163 CLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYEL 222
Query: 1499 FSKALKFDPEN----EYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFY 1554
+++AL DP N + NR N+ L+K ++A ED N ++ + Y RA Y
Sbjct: 223 YTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCY 282
Query: 1555 YCLKQYELAEEDLNKAL---SLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYA 1611
+QYE A D K K + L+ N ++ L + DY + L ++ A
Sbjct: 283 MDTEQYEEAVRDYEKVYQTEKTKEHKQLLKN------AQLELKKSKRKDYYKILGVDKNA 336
Query: 1612 S 1612
S
Sbjct: 337 S 337
Score = 47.0 bits (110), Expect = 1e-04
Identities = 73/312 (23%), Positives = 126/312 (40%), Gaps = 35/312 (11%)
Query: 1016 PTDADIYFRRGEMYEITNKVL-AIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIED 1074
P +A Y R + + A+ D + + D L+ G + N AA
Sbjct: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
Query: 1075 FTALLNIDHQNSQARGQYL---LMMKYYDLAKFTIYQ------IAEMDKGLSELSPMQQ- 1124
F L +DH+N+QA+ ++ +M+Y +A+ + + MD+ L E +P
Sbjct: 63 FQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRAL-EFAPACHR 121
Query: 1125 ---------ALIYSFCENHDKAIEVLDGISWNRAEMTMCAL-LAKVQMKAKRTKEAVEVL 1174
A++ + E A ++L S N + + L L K + V+ L
Sbjct: 122 FKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQAL 181
Query: 1175 KKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYT 1234
+ A D +A A+ A G +EGN YKLA T A+ +D N+
Sbjct: 182 RMAPDHEKACIACRNAKALKAK--KEDGNKAFKEGN----YKLAYELYTEALGIDPNNIK 235
Query: 1235 A----FYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFAL 1290
+ NR +K+R+L A+ D + LD T + +L R Y++ QY A+
Sbjct: 236 TNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT---YIKAYLRRAQCYMDTEQYEEAV 292
Query: 1291 EDFKQAALISRT 1302
D+++ +T
Sbjct: 293 RDYEKVYQTEKT 304
Score = 45.4 bits (106), Expect = 4e-04
Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 898 YESEVKILTEEIN---DKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAY 954
Y+ ++ TE + + K A YC RG + KL KL A+ D + L+ ++ AY
Sbjct: 216 YKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAY 275
Query: 955 WHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSK 991
R Y+ ++ EA+ D +++ K L K
Sbjct: 276 LRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLK 312
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 55.1 bits (131), Expect = 5e-07
Identities = 64/282 (22%), Positives = 109/282 (38%), Gaps = 28/282 (9%)
Query: 1318 NEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIK- 1376
+ F EA++++ A+ P AY+ G M G T++A++ FLK I +K
Sbjct: 541 SRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGR---TEEARRTFLKCSEIPDENLKD 597
Query: 1377 ------ARISFGYNL----QAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNF 1426
+ S YNL QG +++A + + AI P+ + + MG +
Sbjct: 598 PHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQS----LYNMMGEAY 653
Query: 1427 AAMQDINAA---------MKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSL 1477
+ + A K LT G + G K A K + AI L+P
Sbjct: 654 MRLSKLPEAEHWYMESLRSKTDHIPAHLTY-GKLLALTGRKSEAEKLFLKAIELDPTKGN 712
Query: 1478 AYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVI 1537
Y + G + +A++ KA + D V+ N A E A++ +
Sbjct: 713 CYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLAA 772
Query: 1538 ESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDAL 1579
P + A N + + + AE + +AL LKP+D +
Sbjct: 773 RLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDDVI 814
Score = 53.1 bits (126), Expect = 2e-06
Identities = 72/289 (24%), Positives = 117/289 (40%), Gaps = 15/289 (5%)
Query: 1195 ADCLYNLGLCYMEEGNLQMT---YKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQM 1251
AD LYNLGL E YKLAI T S N+ N+ + R +
Sbjct: 527 ADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRT-EEARRTFL 585
Query: 1252 ALTDYGIVLLLD--ATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTN---GSL 1306
++ L D A ++ + N G +Y E G Y AL +K+A SL
Sbjct: 586 KCSEIPDENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSL 645
Query: 1307 CHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLK 1366
+ + R+++ EA +++ +L+ + A++ G G +A+K FLK
Sbjct: 646 YNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGR---KSEAEKLFLK 702
Query: 1367 ALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNF 1426
A+ ++P + +G L + + +A A + D + A + Q N
Sbjct: 703 AIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNE 762
Query: 1427 AAMQ--DINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP 1473
AA + D+ A ++ + A L N G I G Q A +Y A+ L P
Sbjct: 763 AAEKYYDLAARLRPNYPAA-LMNLGAILHLNGRLQKAEANYLRALQLKP 810
Score = 51.2 bits (121), Expect = 8e-06
Identities = 67/316 (21%), Positives = 118/316 (37%), Gaps = 21/316 (6%)
Query: 1225 AISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELG 1284
A+ N YN L + AL Y + + + + +LN G+I + G
Sbjct: 519 ALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAI---GSRPTLASAYLNTGIILMNQG 575
Query: 1285 QYGFALEDFKQAALISRTNGSLCHA-----------TAMCHHRINEFEEAVNFFTWALKI 1333
+ A F + + I N HA +H +EEA++ + A++
Sbjct: 576 RTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQK 635
Query: 1334 NPCFL---DAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGK 1390
P Y G +YM +A+ ++++L +I A +++G L G+
Sbjct: 636 MPRQFAPQSLYNMMGEAYMRLSK---LPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGR 692
Query: 1391 FQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI-STTAEFLTNRG 1449
+A F AI+ DP Y L+ A + A ++ ST + + N
Sbjct: 693 KSEAEKLFLKAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAA 752
Query: 1450 VIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPEN 1509
+ + A K Y A L P Y A N G I + + +A + +AL+ P++
Sbjct: 753 HMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRALQLKPDD 812
Query: 1510 EYVLMNRAITNTILKK 1525
N I++K
Sbjct: 813 VITQSNLRKLWNIMEK 828
Score = 42.4 bits (98), Expect = 0.004
Identities = 61/262 (23%), Positives = 103/262 (39%), Gaps = 28/262 (10%)
Query: 1160 VQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISA-DCLYNLGLCYMEEGNLQMTYKLA 1218
+ M RT+EA K + + K P A S CLYNLG Y E+G+ Y+ A
Sbjct: 570 ILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKLYHEQGH----YEEA 625
Query: 1219 ITDLTTAISMDKNSYT--AFYN-RALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLN 1275
++ AI + + YN Y ++ +L A Y L ++T + L
Sbjct: 626 LSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESL---RSKTDHIPAHLT 682
Query: 1276 RGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEF-------EEAVNFFT 1328
G + G+ A + F +A + T G+ C+ +F EA
Sbjct: 683 YGKLLALTGRKSEAEKLFLKAIELDPTKGN-------CYMHYGQFLLEEARLIEAAEMAK 735
Query: 1329 WALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQ 1388
A +++ D + + +EA A+K + A + P Y A ++ G L
Sbjct: 736 KAAELDSTEFDVVFNAAHMLRQASLNEA---AEKYYDLAARLRPNYPAALMNLGAILHLN 792
Query: 1389 GKFQKAWNHFTIAIDTDPKNYL 1410
G+ QKA ++ A+ P + +
Sbjct: 793 GRLQKAEANYLRALQLKPDDVI 814
Score = 33.9 bits (76), Expect = 1.3
Identities = 61/267 (22%), Positives = 100/267 (37%), Gaps = 21/267 (7%)
Query: 1359 QAQKDFLKALHINPAYIKARISFGYNLQA---QGKFQKAWNHFTIAIDTDPKNYLAYEGR 1415
+ QK FLK+L Y A + Y L+ G +Q + I +P G
Sbjct: 445 KVQKRFLKSLIF---YATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGN 501
Query: 1416 AVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKY 1475
V+ Q + A NA S A+ L N G++ + A+ Y+ AI P
Sbjct: 502 -VLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTL 560
Query: 1476 SLAYFNAGNIYFHHRQFSQASDYFSKALKFDPEN--EYVLMNRAITNTILK--------- 1524
+ AY N G I + + +A F K + EN + ++T+ +
Sbjct: 561 ASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKLYHEQG 620
Query: 1525 KYEEAKEDFANVIESCPFWAA---VYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVY 1581
YEEA + I+ P A +Y Y L + AE ++L K + +
Sbjct: 621 HYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAH 680
Query: 1582 NFRAKVRGKIGLIEEAMADYNQALDLE 1608
K+ G EA + +A++L+
Sbjct: 681 LTYGKLLALTGRKSEAEKLFLKAIELD 707
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sapiens]
Length = 504
Score = 53.5 bits (127), Expect = 2e-06
Identities = 57/238 (23%), Positives = 100/238 (42%), Gaps = 22/238 (9%)
Query: 1373 AYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDI 1432
A ++ + G L A G+ A + F A+D DP NY+AY RA V L MG + AA+ D+
Sbjct: 35 ADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDL 94
Query: 1433 NAA--MKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHR 1490
+K+ TA L RG + G A D++ + NP
Sbjct: 95 TKVIQLKMDFTAARL-QRGHLLLKQGKLDEAEDDFKKVLKSNPSE--------------- 138
Query: 1491 QFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNR 1550
++ + S+ +K D L ++A+ Y A ++E C + A + R
Sbjct: 139 --NEEKEAQSQLIKSDEMQR--LRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELR 194
Query: 1551 AHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
A + + A DL A LK ++ + + + ++G E ++++ + L L+
Sbjct: 195 AECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLD 252
Score = 49.7 bits (117), Expect = 2e-05
Identities = 45/195 (23%), Positives = 81/195 (41%), Gaps = 16/195 (8%)
Query: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978
AY RR ++ +GK ++A+ DL +VI L+ F A R + L Q K++EA DD +
Sbjct: 73 AYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVL 132
Query: 979 KYNKNNTEAYLSKAEIYR---------------GKKDITLAILNYTQAIKSTPTDADIYF 1023
K N + E +++++ + G D T AI + ++ DA++
Sbjct: 133 KSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRE 192
Query: 1024 RRGEMY-EITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNID 1082
R E + + AI D T+A K Y + + ++ + L +D
Sbjct: 193 LRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLD 252
Query: 1083 HQNSQARGQYLLMMK 1097
+ + Y + K
Sbjct: 253 QDHKRCFAHYKQVKK 267
Score = 40.0 bits (92), Expect = 0.018
Identities = 58/318 (18%), Positives = 123/318 (38%), Gaps = 35/318 (11%)
Query: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
+ +A++ F A+ +P AY R ++ G +A A D K + + + AR
Sbjct: 52 QLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKA---ALPDLTKVIQLKMDFTAAR 108
Query: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYE---------------GRAVVCLQMG 1423
+ G+ L QGK +A + F + ++P E +A+ G
Sbjct: 109 LQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSG 168
Query: 1424 NNFAAMQDINAAMKIST-TAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNA 1482
+ AA+ ++ +++ AE R G + A+ D + A L + A++
Sbjct: 169 DYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKI 228
Query: 1483 GNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILK------------KYEEAK 1530
+Y+ + + LK D +++ + + K +Y +A
Sbjct: 229 STLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDAT 288
Query: 1531 EDFANVIESCPFWAA-VYFNRAHFYYCLKQYELAEEDL---NKALSLKPNDALVYNFRAK 1586
+ +V+++ P A ++ +C + E E + ++ L ++P++ RA+
Sbjct: 289 SKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAE 348
Query: 1587 VRGKIGLIEEAMADYNQA 1604
+ +EA+ DY A
Sbjct: 349 AYLIEEMYDEAIQDYETA 366
Score = 38.1 bits (87), Expect = 0.069
Identities = 43/195 (22%), Positives = 82/195 (42%), Gaps = 26/195 (13%)
Query: 1180 AISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNR 1239
AI+ DK + A+ C+++EG + AI+DL A + ++ AFY
Sbjct: 173 AIAFLDKILEVCVWDAELRELRAECFIKEGEPRK----AISDLKAASKLKNDNTEAFYKI 228
Query: 1240 ALCYTKIRELQMALTDYGIVLLLDA---------TETVKLNTFLNRGLIYVELGQYGFAL 1290
+ Y ++ + +++L++ L LD + KLN + + G+Y A
Sbjct: 229 STLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDAT 288
Query: 1291 EDFKQ--------AALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYV 1342
++ A R+ +CH C + + EA+ + L++ P ++A
Sbjct: 289 SKYESVMKTEPSIAEYTVRSKERICH----CFSKDEKPVEAIRVCSEVLQMEPDNVNALK 344
Query: 1343 GRGNSYM-EYGHDEA 1356
R +Y+ E +DEA
Sbjct: 345 DRAEAYLIEEMYDEA 359
Score = 32.7 bits (73), Expect = 2.9
Identities = 42/206 (20%), Positives = 84/206 (40%), Gaps = 28/206 (13%)
Query: 931 GKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLS 990
G+L A++ + +P AY+ R ++L K AL DL + + + T A L
Sbjct: 51 GQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQ 110
Query: 991 KAEIYRGKKDITLAILNYTQAIKSTPTDAD------IYFRRGEMYEITNKVL---AIDDF 1041
+ + + + A ++ + +KS P++ + + EM + ++ L D+
Sbjct: 111 RGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDY 170
Query: 1042 SKCIFYDPKRTDAL--------LKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYL 1093
+ I + K + L+ F E E AI D A + + N++A
Sbjct: 171 TAAIAFLDKILEVCVWDAELRELRAECFIKEGEP-RKAISDLKAASKLKNDNTEA----- 224
Query: 1094 LMMKYYDLAKFTIYQIAEMDKGLSEL 1119
+Y ++ YQ+ + + LSE+
Sbjct: 225 ----FYKISTL-YYQLGDHELSLSEV 245
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 52.8 bits (125), Expect = 3e-06
Identities = 50/228 (21%), Positives = 95/228 (41%), Gaps = 4/228 (1%)
Query: 1350 EYGHDEATKQ----AQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTD 1405
E G+D K+ A K + KA ++P + + +G + K AI+
Sbjct: 230 ELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVG 289
Query: 1406 PKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDY 1465
+N Y A ++GN++ + A+ + + + + +K+
Sbjct: 290 RENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQ 349
Query: 1466 QDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKK 1525
+ +NP +L N GN F + QA ++++A+K +P++ + NRA T L +
Sbjct: 350 ERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLE 409
Query: 1526 YEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSL 1573
++ A +D I+ P + Y +A +K Y A + KAL L
Sbjct: 410 FQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDL 457
Score = 48.5 bits (114), Expect = 5e-05
Identities = 52/229 (22%), Positives = 95/229 (41%), Gaps = 41/229 (17%)
Query: 1421 QMGNNFAAMQDINAAMKI--------STTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLN 1472
++GN+ +D + A+K T ++TN+ ++ G + + AI +
Sbjct: 230 ELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVG 289
Query: 1473 PK-------YSLAYFNAGNIYFHHRQFSQASDYFSKAL----------------KFDPEN 1509
+ + AY GN YF ++ A +++K+L K E
Sbjct: 290 RENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQ 349
Query: 1510 E---YVLMNRAIT-----NTILKK--YEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQ 1559
E Y+ + A+ N +K Y +A + + I+ P A +Y NRA Y L +
Sbjct: 350 ERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLE 409
Query: 1560 YELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
++LA +D + + L+P Y +A + +AM Y +ALDL+
Sbjct: 410 FQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLD 458
Score = 40.8 bits (94), Expect = 0.011
Identities = 48/188 (25%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 917 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLE--PLFLNAYWHRHLIYLFQDKINEALDDL 974
A AY R G Y K K + A++ + + P L I Q+++ DL
Sbjct: 300 AKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDL 359
Query: 975 NYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMY-EITN 1033
K NK N E ++ K D A+ +YT+AIK P DA +Y R Y ++
Sbjct: 360 ALEEK-NKGN--------ECFQ-KGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLE 409
Query: 1034 KVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQAR-GQY 1092
LA+ D +CI +P ++ +++ A++ + L++D +A G
Sbjct: 410 FQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQ 469
Query: 1093 LLMMKYYD 1100
MM Y+
Sbjct: 470 RCMMAQYN 477
Score = 40.4 bits (93), Expect = 0.014
Identities = 24/95 (25%), Positives = 40/95 (42%)
Query: 1483 GNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPF 1542
GN A +S+A+K DP N + NR+ Y++A ED ++ P
Sbjct: 11 GNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPD 70
Query: 1543 WAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPND 1577
W Y +A L ++E A+ + L + N+
Sbjct: 71 WGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANN 105
Score = 36.2 bits (82), Expect = 0.26
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 898 YESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAY 954
Y +K TE I K A Y R A Y KL + Q A+ D + I LEP F+ Y
Sbjct: 376 YPQAMKHYTEAIKRNPK-DAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGY 431
Score = 35.8 bits (81), Expect = 0.34
Identities = 19/51 (37%), Positives = 26/51 (50%)
Query: 1215 YKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDAT 1265
Y A+ T AI + + NRA CYTK+ E Q+AL D + L+ T
Sbjct: 376 YPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPT 426
Score = 35.4 bits (80), Expect = 0.45
Identities = 56/266 (21%), Positives = 97/266 (36%), Gaps = 26/266 (9%)
Query: 1175 KKALD-AISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSY 1233
KK D A+ H DK + + + N Y E+G+ +L AI + + +
Sbjct: 238 KKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELC----EKAIEVGRENR 293
Query: 1234 TAFYNRALCYTKI-------RELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQY 1286
+ A Y +I + + A+ Y L T V L I E +
Sbjct: 294 EDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDV-LKKCQQAEKILKEQERL 352
Query: 1287 GFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGN 1346
+ D AL + G+ C ++ +A+ +T A+K NP Y R
Sbjct: 353 AYINPDL---ALEEKNKGNECFQKG-------DYPQAMKHYTEAIKRNPKDAKLYSNRAA 402
Query: 1347 SYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDP 1406
Y + + A KD + + + P +IK L+A + KA + + A+D D
Sbjct: 403 CYTKLLEFQL---ALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDS 459
Query: 1407 KNYLAYEGRAVVCLQMGNNFAAMQDI 1432
A +G + N + +D+
Sbjct: 460 SCKEAADGYQRCMMAQYNRHDSPEDV 485
Score = 33.9 bits (76), Expect = 1.3
Identities = 23/82 (28%), Positives = 38/82 (46%)
Query: 1527 EEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAK 1586
++A + ++ I+ P +Y NR+ Y Y+ A ED K + LKP+ Y+ +A
Sbjct: 21 DDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAA 80
Query: 1587 VRGKIGLIEEAMADYNQALDLE 1608
+ EEA Y + L E
Sbjct: 81 ALEFLNRFEEAKRTYEEGLKHE 102
Score = 33.1 bits (74), Expect = 2.2
Identities = 19/79 (24%), Positives = 36/79 (45%)
Query: 1455 MGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLM 1514
+G+ +A++ Y +AI L+P + Y N Y + +A + K + P+
Sbjct: 17 VGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYS 76
Query: 1515 NRAITNTILKKYEEAKEDF 1533
+A L ++EEAK +
Sbjct: 77 RKAAALEFLNRFEEAKRTY 95
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 52.0 bits (123), Expect = 5e-06
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 8/120 (6%)
Query: 1414 GRAVVCLQMGNNFAAMQDINAAMKIST--------TAEFLTNRGVIHEFMGHKQNAMKDY 1465
G+A GNN ++ AA+ T A + NR +GH +A+KD
Sbjct: 83 GKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDC 142
Query: 1466 QDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKK 1525
+ AI ++ KYS AY G +F +A + KAL DPEN+ N I L++
Sbjct: 143 EKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
Score = 47.0 bits (110), Expect = 1e-04
Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 14/159 (8%)
Query: 1314 HHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPA 1373
H + + AV+ +T A++++P Y R + + GH A KD KA+ I+
Sbjct: 95 HMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGH---YTDAIKDCEKAIAIDSK 151
Query: 1374 YIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQ----------MG 1423
Y KA G L A KF++A + A+D DP+N +Y+ + Q G
Sbjct: 152 YSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEND-SYKSNLKIAEQKLREVSSPTGTG 210
Query: 1424 NNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAM 1462
+F IN IS A + N V G NA+
Sbjct: 211 LSFDMASLINNPAFISMAASLMQNPQVQQLMSGMMTNAI 249
Score = 42.7 bits (99), Expect = 0.003
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1483 GNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPF 1542
GN + ++ A D +++A++ DP N NRA + L Y +A +D I
Sbjct: 92 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSK 151
Query: 1543 WAAVYFNRAHFYYCLKQYELAEEDLNKALSLKP-NDALVYNFR 1584
++ Y L ++E A KAL L P ND+ N +
Sbjct: 152 YSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLK 194
Score = 37.4 bits (85), Expect = 0.12
Identities = 25/85 (29%), Positives = 37/85 (43%)
Query: 1524 KKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNF 1583
+ Y A + + IE P A Y NRA L Y A +D KA+++ + Y
Sbjct: 99 ENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGR 158
Query: 1584 RAKVRGKIGLIEEAMADYNQALDLE 1608
+ EEA+ Y +ALDL+
Sbjct: 159 MGLALTALNKFEEAVTSYQKALDLD 183
Score = 36.6 bits (83), Expect = 0.20
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 7/139 (5%)
Query: 860 KDDKISVPEDPPERVKEPPKLKLNDYVESDLPQEVIKYYESEVKILTEEINDKTKYPAFA 919
K+D + + PE V + +LK D + + +E Y + V T+ I + A
Sbjct: 68 KNDVLPLSNSVPEDVGKADQLK--DEGNNHMKEE---NYAAAVDCYTQAI-ELDPNNAVY 121
Query: 920 YCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHK 979
YC R A KLG A+ D ++ I ++ + AY L +K EA+
Sbjct: 122 YCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALD 181
Query: 980 YNKNNTEAYLSKAEIYRGK 998
+ N ++Y S +I K
Sbjct: 182 LDPEN-DSYKSNLKIAEQK 199
Score = 36.2 bits (82), Expect = 0.26
Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 12/164 (7%)
Query: 1179 DAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYN 1238
D + S+ P+ AD L + G +M+E N Y A+ T AI +D N+ + N
Sbjct: 70 DVLPLSNSVPEDVG-KADQLKDEGNNHMKEEN----YAAAVDCYTQAIELDPNNAVYYCN 124
Query: 1239 RALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAAL 1298
RA +K+ A+ D + +D+ + + GL L ++ A+ +++A
Sbjct: 125 RAAAQSKLGHYTDAIKDCEKAIAIDSKYS---KAYGRMGLALTALNKFEEAVTSYQKALD 181
Query: 1299 ISRTNGSLCHATAMCHHRINEFEE----AVNFFTWALKINPCFL 1338
+ N S + ++ E ++F +L NP F+
Sbjct: 182 LDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFI 225
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 51.6 bits (122), Expect = 6e-06
Identities = 53/221 (23%), Positives = 92/221 (41%), Gaps = 14/221 (6%)
Query: 1402 IDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQN 1460
+D DP N + RA ++ A D N A+ ++ + + + RG + +
Sbjct: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
Query: 1461 AMKDYQDAITLNP----------KYSLAYFNAGNIYFHHRQFS-QASDYFSKALKFDPEN 1509
A KDY+ + L P K S A + N Y ++++ K ++
Sbjct: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
Query: 1510 EYVLMNRAITNTILK--KYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDL 1567
+ + + N K KYE A E + I + A + NRA Y +++YE AE+D
Sbjct: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
Query: 1568 NKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
+A+ L + + + R R +G + EA D+ L LE
Sbjct: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 221
Score = 45.4 bits (106), Expect = 4e-04
Identities = 47/232 (20%), Positives = 94/232 (40%), Gaps = 20/232 (8%)
Query: 1360 AQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVC 1419
A+ D A+ +N +Y KA G A K ++A + ++ +P
Sbjct: 27 AESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP------------- 73
Query: 1420 LQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAY 1479
NNF A ++ KIS N + K + Q N + +++
Sbjct: 74 ----NNFEATNELR---KISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISE 126
Query: 1480 FNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIES 1539
+ GN +F ++ +A + +++ + D N + NRA+ ++KYEEA++D I
Sbjct: 127 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 186
Query: 1540 CPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKI 1591
++ + R L + A++D L L+P + +K++ ++
Sbjct: 187 DGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 238
Score = 38.5 bits (88), Expect = 0.053
Identities = 57/220 (25%), Positives = 96/220 (43%), Gaps = 35/220 (15%)
Query: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978
AY RRGA L KL+ A D +RV+ LEP N + EA ++L I
Sbjct: 44 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 86
Query: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034
+ + +Y +A+I G++ A N QAI S + +F+ G+ YE
Sbjct: 87 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 140
Query: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA---RGQ 1091
AI+ +++ I D R + Y + + + A +D T + +D S+A RG
Sbjct: 141 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGT 199
Query: 1092 YLLMMKYYDLAKFTIYQIAEMDKG----LSELSPMQQALI 1127
+ + AK + ++ G ++ELS +++ LI
Sbjct: 200 ARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELI 239
Score = 37.7 bits (86), Expect = 0.091
Identities = 35/136 (25%), Positives = 56/136 (41%), Gaps = 22/136 (16%)
Query: 1168 KEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAIS 1227
++ +E + AIS D+G + +EG Y+ AI T I+
Sbjct: 111 RKQIEAQQNKQQAISEKDRGNG---------------FFKEGK----YERAIECYTRGIA 151
Query: 1228 MDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYG 1287
D + NRA+ Y KI++ + A D +LLD + + F RG LG+
Sbjct: 152 ADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYS---KAFARRGTARTFLGKLN 208
Query: 1288 FALEDFKQAALISRTN 1303
A +DF+ L+ N
Sbjct: 209 EAKQDFETVLLLEPGN 224
Score = 34.7 bits (78), Expect = 0.77
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334
+RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++
Sbjct: 128 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 187
Query: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372
+ A+ RG + G +A++DF L + P
Sbjct: 188 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 222
Score = 34.3 bits (77), Expect = 1.0
Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948
I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP
Sbjct: 170 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 222
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 48.1 bits (113), Expect = 7e-05
Identities = 30/107 (28%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Query: 1420 LQMGNNFAAMQDINAAMKIS-TTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLA 1478
+++ N AA+ A++++ A + NR + +G+ A++D + AI ++P YS A
Sbjct: 102 MKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKA 161
Query: 1479 YFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKK 1525
Y G + +A Y+ KAL+ DP+NE N I L++
Sbjct: 162 YGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLRE 208
Score = 46.2 bits (108), Expect = 3e-04
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 1316 RINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYI 1375
++ FE AV+F+ A+++NP + R +Y + G+ Q D +A+ I+PAY
Sbjct: 103 KVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQ---DCERAICIDPAYS 159
Query: 1376 KARISFGYNLQAQGKFQKAWNHFTIAIDTDPKN 1408
KA G L + K +A ++ A++ DP N
Sbjct: 160 KAYGRMGLALSSLNKHVEAVAYYKKALELDPDN 192
Score = 38.5 bits (88), Expect = 0.053
Identities = 42/160 (26%), Positives = 64/160 (40%), Gaps = 22/160 (13%)
Query: 847 LIEYKDASIPVKEKDDKISVPEDPP---ERVKEPPKLKL--NDYVESDLPQEVIKYYESE 901
L E +A+ KE + P P E E +LK N+ ++ + + + +Y
Sbjct: 58 LPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKA 117
Query: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961
+ E+N A +C R A Y KLG A+ D +R I ++P + AY L
Sbjct: 118 I-----ELNPAN---AVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLAL 169
Query: 962 LFQDKINEA---------LDDLNYIHKYNKNNTEAYLSKA 992
+K EA LD N +K N E L +A
Sbjct: 170 SSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREA 209
Score = 38.1 bits (87), Expect = 0.069
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1245 KIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNG 1304
K+ + A+ YG + L+ V F NR Y +LG Y A++D ++A I
Sbjct: 103 KVENFEAAVHFYGKAIELNPANAVY---FCNRAAAYSKLGNYAGAVQDCERAICIDPAYS 159
Query: 1305 SLCHATAMCHHRINEFEEAVNFFTWALKINP 1335
+ +N+ EAV ++ AL+++P
Sbjct: 160 KAYGRMGLALSSLNKHVEAVAYYKKALELDP 190
Score = 35.4 bits (80), Expect = 0.45
Identities = 25/95 (26%), Positives = 38/95 (40%)
Query: 1483 GNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPF 1542
GN F A ++ KA++ +P N NRA + L Y A +D I P
Sbjct: 98 GNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPA 157
Query: 1543 WAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPND 1577
++ Y L ++ A KAL L P++
Sbjct: 158 YSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDN 192
>gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens]
Length = 151
Score = 47.0 bits (110), Expect = 1e-04
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
Query: 1427 AAMQDINAAMKISTT--AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGN 1484
AA D + K S A NRG I F AM DY AI + P + + Y+N G
Sbjct: 41 AASSDESPGSKCSPEDLATAYNNRGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGL 100
Query: 1485 IYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534
I + F A + F K L +P + + ++ TIL K E+ + + A
Sbjct: 101 ILYRLGYFDDALEDFKKVLDLNPGFQDATL--SLKQTILDKEEKQRRNVA 148
Score = 37.7 bits (86), Expect = 0.091
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 1544 AAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQ 1603
A Y NR Y + A +D A+ ++PN + Y R + ++G ++A+ D+ +
Sbjct: 58 ATAYNNRGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDFKK 117
Query: 1604 ALDL 1607
LDL
Sbjct: 118 VLDL 121
Score = 37.4 bits (85), Expect = 0.12
Identities = 20/64 (31%), Positives = 32/64 (50%)
Query: 1478 AYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVI 1537
AY N G I + F +A D ++ A++ P E NR + L +++A EDF V+
Sbjct: 60 AYNNRGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDFKKVL 119
Query: 1538 ESCP 1541
+ P
Sbjct: 120 DLNP 123
Score = 36.6 bits (83), Expect = 0.20
Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 1495 ASDYFSKALKFDPEN-EYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHF 1553
AS S K PE+ NR + EA +D+ + IE P + Y+NR
Sbjct: 42 ASSDESPGSKCSPEDLATAYNNRGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGLI 101
Query: 1554 YYCLKQYELAEEDLNKALSLKP 1575
Y L ++ A ED K L L P
Sbjct: 102 LYRLGYFDDALEDFKKVLDLNP 123
Score = 34.7 bits (78), Expect = 0.77
Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
+F EA++ +T A+++ P F Y RG G+ + A +DF K L +NP + A
Sbjct: 73 DFYEAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFD---DALEDFKKVLDLNPGFQDAT 129
Query: 1379 IS 1380
+S
Sbjct: 130 LS 131
Score = 32.0 bits (71), Expect = 5.0
Identities = 24/84 (28%), Positives = 37/84 (44%)
Query: 917 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNY 976
A AY RG I AM+D I ++P F Y++R LI ++AL+D
Sbjct: 58 ATAYNNRGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDFKK 117
Query: 977 IHKYNKNNTEAYLSKAEIYRGKKD 1000
+ N +A LS + K++
Sbjct: 118 VLDLNPGFQDATLSLKQTILDKEE 141
>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
sapiens]
Length = 833
Score = 46.6 bits (109), Expect = 2e-04
Identities = 37/163 (22%), Positives = 69/163 (42%), Gaps = 1/163 (0%)
Query: 914 KYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDD 973
+Y A +G G + A + + + A ++ L Y ++++EALD
Sbjct: 490 RYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDC 549
Query: 974 LNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEIT- 1032
+H +N+ E A IY ++ + AI Q + PTD + + GE+Y+
Sbjct: 550 FLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREG 609
Query: 1033 NKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDF 1075
+K A + + Y P + + G +Y + + W AI+ F
Sbjct: 610 DKSQAFQYYYESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYF 652
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/297 (20%), Positives = 110/297 (37%), Gaps = 22/297 (7%)
Query: 1135 DKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKAL--------DAISHSDK 1186
+KA+ L +N+A +L ++ K R K A AL A S++D
Sbjct: 429 NKAVTYLRQKDYNQA----VEILKVLEKKDSRVKSAAATNLSALYYMGKDFAQASSYADI 484
Query: 1187 GPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKI 1246
++ + L N G G+ Y+ A A+ D + A YN L Y K+
Sbjct: 485 AVNSDRYNPAALTNKGNTVFANGD----YEKAAEFYKEALRNDSSCTEALYNIGLTYEKL 540
Query: 1247 RELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSL 1306
L AL + L L A IY + A+E Q + T+ +
Sbjct: 541 NRLDEALDCF---LKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQV 597
Query: 1307 CHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLK 1366
+ R + +A ++ + + PC ++ G Y++ + ++A + F +
Sbjct: 598 LSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVIEWLGAYYID---TQFWEKAIQYFER 654
Query: 1367 ALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMG 1423
A I P +K ++ + G +QKA + + P+N +C +G
Sbjct: 655 ASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDTHRKFPENVECLRFLVRLCTDLG 711
Score = 40.0 bits (92), Expect = 0.018
Identities = 87/436 (19%), Positives = 159/436 (36%), Gaps = 80/436 (18%)
Query: 1199 YNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGI 1258
Y++ Y E N TY++ + + M N+ N Y K R A+ Y +
Sbjct: 216 YSVNEMYAEALN---TYQVIVKN-----KMFSNAGILKMNMGNIYLKQRNYSKAIKFYRM 267
Query: 1259 VL--LLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHR 1316
L + + +++ N G+ +++ GQY A+ ++ ++ N + +C+
Sbjct: 268 ALDQVPSVNKQMRIKIMQNIGVTFIQAGQYSDAINSYEHIMSMA-PNLKAGYNLTICYFA 326
Query: 1317 INEFEEAVNFF----TWALKINPCFLDAYVGRG-------------NSYMEYGHDEATKQ 1359
I + E+ F T L+I+ D Y+ N ++ E
Sbjct: 327 IGDREKMKKAFQKLITVPLEIDE---DKYISPSDDPHTNLVTEAIKNDHLRQMERERKAM 383
Query: 1360 AQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVC 1419
A+K + + + I+ + GY+ + KA + +A D + + Y
Sbjct: 384 AEKYIMTSAKLIAPVIETSFAAGYDWCVE--VVKASQYVELANDLEINKAVTY------- 434
Query: 1420 LQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAY 1479
+D N A++I E K + +K S A
Sbjct: 435 -------LRQKDYNQAVEILKVLE-------------KKDSRVK------------SAAA 462
Query: 1480 FNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIES 1539
N +Y+ + F+QAS Y A+ D N L N+ T YE+A E + + +
Sbjct: 463 TNLSALYYMGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRN 522
Query: 1540 CPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMA 1599
+N Y L + + A + K ++ N A+V +I I E M
Sbjct: 523 DSSCTEALYNIGLTYEKLNRLDEALDCFLKLHAILRNS-------AEVLYQIANIYELME 575
Query: 1600 DYNQALD-LEDYASVI 1614
+ +QA++ L SVI
Sbjct: 576 NPSQAIEWLMQVVSVI 591
Score = 36.2 bits (82), Expect = 0.26
Identities = 64/353 (18%), Positives = 132/353 (37%), Gaps = 54/353 (15%)
Query: 1199 YNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSY--------TAFYNRALCYTKIRELQ 1250
YNL +CY G+ + K +T + +D++ Y T A+ +R+++
Sbjct: 318 YNLTICYFAIGDREKMKKAFQKLITVPLEIDEDKYISPSDDPHTNLVTEAIKNDHLRQME 377
Query: 1251 ---------MALTDYGIVLLLDAT----------ETVKLNTF--------LNRGLIYVEL 1283
+T ++ + T E VK + + +N+ + Y+
Sbjct: 378 RERKAMAEKYIMTSAKLIAPVIETSFAAGYDWCVEVVKASQYVELANDLEINKAVTYLRQ 437
Query: 1284 GQYGFALEDFK-QAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYV 1342
Y A+E K SR + + ++ +F +A ++ A+ + A
Sbjct: 438 KDYNQAVEILKVLEKKDSRVKSAAATNLSALYYMGKDFAQASSYADIAVNSDRYNPAALT 497
Query: 1343 GRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAI 1402
+GN+ G E +A + + +AL + + +A + G + + + A+
Sbjct: 498 NKGNTVFANGDYE---KAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDE-------AL 547
Query: 1403 DTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMK--------ISTTAEFLTNRGVIHEF 1454
D K + A V Q+ N + M++ + A++ I T + L+ G +++
Sbjct: 548 DCFLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDR 607
Query: 1455 MGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDP 1507
G K A + Y ++ P G Y + + +A YF +A P
Sbjct: 608 EGDKSQAFQYYYESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQP 660
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,746,204
Number of Sequences: 37866
Number of extensions: 2775762
Number of successful extensions: 11990
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 151
Number of HSP's that attempted gapping in prelim test: 10740
Number of HSP's gapped (non-prelim): 1057
length of query: 1614
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1498
effective length of database: 13,855,062
effective search space: 20754882876
effective search space used: 20754882876
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.