Guide to the Human Genome
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Search of human proteins with 116812573

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116812573 CWC15 homolog [Homo sapiens]
         (229 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116812573 CWC15 homolog [Homo sapiens]                             459   e-130
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                58   8e-09
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    50   2e-06
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom...    49   5e-06
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom...    49   5e-06
gi|221219020 NYD-SP11 protein [Homo sapiens]                           48   8e-06
gi|21314720 Smad nuclear interacting protein [Homo sapiens]            45   7e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             45   7e-05
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        45   7e-05
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap...    44   9e-05
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap...    44   9e-05
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    44   1e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    44   2e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    44   2e-04
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]     43   3e-04
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso...    42   3e-04
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            42   4e-04
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]            42   6e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         42   6e-04
gi|56549694 enabled homolog isoform a [Homo sapiens]                   41   7e-04
gi|39930375 enabled homolog isoform b [Homo sapiens]                   41   7e-04
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             41   7e-04
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    41   7e-04
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    41   7e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens]               41   0.001
gi|148746195 trichohyalin [Homo sapiens]                               41   0.001
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]          41   0.001
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo...    41   0.001
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo...    41   0.001
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           41   0.001

>gi|116812573 CWC15 homolog [Homo sapiens]
          Length = 229

 Score =  459 bits (1181), Expect = e-130
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFR 60
           MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFR
Sbjct: 1   MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFR 60

Query: 61  RELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEE 120
           RELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEE
Sbjct: 61  RELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEE 120

Query: 121 SDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQA 180
           SDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQA
Sbjct: 121 SDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQA 180

Query: 181 NFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK 229
           NFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK
Sbjct: 181 NFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK 229


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 3/141 (2%)

Query: 22  DLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRR---ELEERERAAAREKNRDR 78
           D++ +  +   RDL S    K+R T +   EE   ++  R   E E RER   RE+ R+R
Sbjct: 263 DINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER 322

Query: 79  PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK 138
             RE        ++   ++      D D   T E D D + E D D      ++  K + 
Sbjct: 323 REREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS 382

Query: 139 ERAEEQARKEQEQKAEEERIR 159
              E+   +E+E++ E ER R
Sbjct: 383 RSREKSRDRERERERERERER 403



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 7/133 (5%)

Query: 40  KIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIP 99
           K K R   +D  +    R   R+L E+E AA +E+ ++   RE   +    K+   ++  
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKE-AAYQERLKNWEIRERKKTREYEKEAEREEER 485

Query: 100 AANLDADDPLTDEEDEDFEEESDDDD---TAALLAELEKIKKE-RAEEQARKEQEQKAEE 155
              +  +     E  ED++++ DD      +AL   L   +KE  A+E+ RK ++++ EE
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEE 545

Query: 156 ERIRMENILSGNP 168
             IR   +  G+P
Sbjct: 546 --IRQRLLAEGHP 556



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 37/161 (22%), Positives = 73/161 (45%), Gaps = 13/161 (8%)

Query: 6   RPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELE- 64
           R T +     +GK E +  ++ K+   R+     + + R+  ++   E R R+  +E E 
Sbjct: 285 RDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERE-REREKEKERER 343

Query: 65  --ERERAAAREKNRDRP-TREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEES 121
             ER+R   R K RDR   RE             D+  +++ + D   + E+  D E E 
Sbjct: 344 ERERDRDRDRTKERDRDRDRERDRDR--------DRERSSDRNKDRSRSREKSRDRERER 395

Query: 122 DDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMEN 162
           + +       E E+ ++   E +  +E+E++ +++R R E+
Sbjct: 396 EREREREREREREREREREREREREREREREKDKKRDREED 436



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 17/136 (12%)

Query: 40  KIKYRQTTQDAPEEVRNRDFRRELEE-RERAAAREKNRDRPT-REHTTSSSVSKKPRLDQ 97
           + K R   +D  E  R+RD  R  +  ++R+ +REK+RDR   RE        ++   ++
Sbjct: 353 RTKERDRDRDR-ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411

Query: 98  IPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARK---------- 147
                 + +     E+D+  + E D++D         K++++ A  Q R           
Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKK 471

Query: 148 ----EQEQKAEEERIR 159
               E+E + EEER R
Sbjct: 472 TREYEKEAEREEERRR 487



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 13/110 (11%)

Query: 48  QDAPEEVRNRDFRRELEERERAA-AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDAD 106
           +D P+  R    ++ L +RE+   A E++R R            +K  L++I    L   
Sbjct: 507 RDDPKYYRGSALQKRLRDREKEMEADERDRKR------------EKEELEEIRQRLLAEG 554

Query: 107 DPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEE 156
            P  D E +  E+E++      +  E E  ++E  +++  +++E+  EEE
Sbjct: 555 HPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604



 Score = 32.0 bits (71), Expect = 0.45
 Identities = 30/120 (25%), Positives = 54/120 (45%), Gaps = 3/120 (2%)

Query: 44  RQTTQDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN 102
           R+ ++D   E R R+  RE E ERER   RE+ R+R  RE        +    D+  A  
Sbjct: 385 REKSRDRERE-RERERERERERERERERERERERER-EREREREKDKKRDREEDEEDAYE 442

Query: 103 LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMEN 162
               +    E++  ++E   + +        E  K+   EE+ R+E  ++A+  +  +E+
Sbjct: 443 RRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED 502



 Score = 31.2 bits (69), Expect = 0.77
 Identities = 37/129 (28%), Positives = 55/129 (42%), Gaps = 21/129 (16%)

Query: 52  EEVRNRD--FRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQI----PAANLDA 105
           EE + RD   +  +E   R  + E N   P++E  +     KK + + I    P A L  
Sbjct: 198 EETKRRDQMIKGAIEVLIREYSSELNA--PSQESDSHPRKKKKEKKEDIFRRFPVAPLIP 255

Query: 106 DDPLTDEEDEDFEEESDDDDTAAL----------LAELEKIKKERAE---EQARKEQEQK 152
              +T E+    E E D  D  +             E EK KKE+     E+ R+E+E++
Sbjct: 256 YPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERE 315

Query: 153 AEEERIRME 161
            E ER R E
Sbjct: 316 RERERERRE 324


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 6/121 (4%)

Query: 48  QDAPEEVRNRD-----FRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN 102
           Q   EE+  R+      R+  EER R  A+E+ ++R  +EH      + + RL+QI    
Sbjct: 588 QREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTE 647

Query: 103 LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMEN 162
           L A     D + ED EE   D   A  + +LEK KKE  E    +E++    E   R+E 
Sbjct: 648 LGA-KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEE 706

Query: 163 I 163
           I
Sbjct: 707 I 707



 Score = 32.0 bits (71), Expect = 0.45
 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 12/122 (9%)

Query: 48  QDAPEEVRNRDFRRE--LEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDA 105
           Q   E +      RE  LE + R +   ++RD        +     + +L Q        
Sbjct: 727 QQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQF------- 779

Query: 106 DDPLTDEEDEDFEE---ESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMEN 162
           ++ L +E     EE   +  ++       E E+ ++ RAEEQ  KE+E++   ER + E 
Sbjct: 780 EERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREE 839

Query: 163 IL 164
            L
Sbjct: 840 EL 841



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 34/143 (23%), Positives = 63/143 (44%), Gaps = 7/143 (4%)

Query: 24  SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREH 83
           +++S+    RDL     ++ +   Q   EE   +   R  EER     R + R R  +E 
Sbjct: 748 NRMSRMLEDRDL---FVMRLKAARQSVYEEKLKQFEERLAEERHN---RLEERKRQRKEE 801

Query: 84  TTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKI-KKERAE 142
              +   +K   +Q  A      +    E  E  + E +  +    + +LE++ +K+R  
Sbjct: 802 RRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQR 861

Query: 143 EQARKEQEQKAEEERIRMENILS 165
           E   +E+E++ EEER   ++ LS
Sbjct: 862 ELEIEERERRREEERRLGDSSLS 884



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 12/131 (9%)

Query: 40   KIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIP 99
            K K R+ +   P E       R  EERE    +E++RD   RE        K P  ++  
Sbjct: 1181 KEKAREESWGPPRE------SRPSEEREWDREKERDRDNQDREEN-----DKDPERERDR 1229

Query: 100  AANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEER-I 158
              ++D +D      DE        +++++      +  ++R + +  ++  +   E R +
Sbjct: 1230 ERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDL 1289

Query: 159  RMENILSGNPL 169
            R +    G PL
Sbjct: 1290 RDDRDRRGPPL 1300



 Score = 28.5 bits (62), Expect = 5.0
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 23/115 (20%)

Query: 44   RQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANL 103
            R+  +D  +  R RD RR+L ER         R  P R  +    VS   R D      +
Sbjct: 1264 RRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLR--SEREEVSSWRRADDRKDDRV 1321

Query: 104  DADDP--------LTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQE 150
            +  DP        L+ + + D + E + +             KE+A  +A K++E
Sbjct: 1322 EERDPPRRVPPPALSRDRERDRDREREGE-------------KEKASWRAEKDRE 1363



 Score = 27.7 bits (60), Expect = 8.5
 Identities = 11/29 (37%), Positives = 21/29 (72%)

Query: 133 LEKIKKERAEEQARKEQEQKAEEERIRME 161
           +++ K+E  + +A  ++ +KAEEER+R E
Sbjct: 587 IQREKEELEQREAELQKVRKAEEERLRQE 615


>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
            sapiens]
          Length = 1108

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 13/104 (12%)

Query: 60   RRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEE 119
            +RE EER+     E   +  + EH  + +   +         + D  + LT EEDED E+
Sbjct: 971  KREAEERDSTEQEEAGPEILSNEHVGARASPSQ--------GDSDERESLTREEDEDSEK 1022

Query: 120  ESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163
            E +++D      E+E++++E+  E+ + ++E++ EEE +  E +
Sbjct: 1023 EEEEED-----KEMEELQEEKECEKPQGDEEEEEEEEEVEEEEV 1061



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 21/106 (19%)

Query: 64   EERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDD 123
            +ERE +  RE++ D    E      + +            + + P  DEE+E+ EEE ++
Sbjct: 1007 DERE-SLTREEDEDSEKEEEEEDKEMEELQE-------EKECEKPQGDEEEEEEEEEVEE 1058

Query: 124  DDTAALLAELEKIKKE------RAEEQAR-------KEQEQKAEEE 156
            ++      E E+ K E      RAE QA        +  EQ +EE+
Sbjct: 1059 EEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEK 1104


>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
            sapiens]
          Length = 1124

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 13/104 (12%)

Query: 60   RRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEE 119
            +RE EER+     E   +  + EH  + +   +         + D  + LT EEDED E+
Sbjct: 987  KREAEERDSTEQEEAGPEILSNEHVGARASPSQ--------GDSDERESLTREEDEDSEK 1038

Query: 120  ESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163
            E +++D      E+E++++E+  E+ + ++E++ EEE +  E +
Sbjct: 1039 EEEEED-----KEMEELQEEKECEKPQGDEEEEEEEEEVEEEEV 1077



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 21/106 (19%)

Query: 64   EERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDD 123
            +ERE +  RE++ D    E      + +            + + P  DEE+E+ EEE ++
Sbjct: 1023 DERE-SLTREEDEDSEKEEEEEDKEMEELQE-------EKECEKPQGDEEEEEEEEEVEE 1074

Query: 124  DDTAALLAELEKIKKE------RAEEQAR-------KEQEQKAEEE 156
            ++      E E+ K E      RAE QA        +  EQ +EE+
Sbjct: 1075 EEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEK 1120


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 9/151 (5%)

Query: 20   EGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRP 79
            E  L +L KQ S   L S  + +  +  +   EEVR  +  R+ EE       EK  ++ 
Sbjct: 2231 ESLLDELEKQES---LSSEEEEEREEEEEREEEEVREEEEERKEEEE----GEEKQVEKE 2283

Query: 80   TREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKE 139
              E        KK  + +      + ++ +++EE E   +E +++++ +L  E+++ K+ 
Sbjct: 2284 EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEI 2343

Query: 140  RAEEQARKEQEQ--KAEEERIRMENILSGNP 168
              +E+  K QEQ  K+   R R+ +IL G P
Sbjct: 2344 LKKEKQFKLQEQRRKSLRGRERVLSILRGVP 2374



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 19/55 (34%), Positives = 33/55 (60%)

Query: 107  DPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
            +  + + DE   EE   ++  +LL ELEK +   +EE+  +E+E++ EEE +R E
Sbjct: 2211 EKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 30/152 (19%), Positives = 67/152 (44%), Gaps = 14/152 (9%)

Query: 26   LSKQYSSRDLPSHTKIKYRQTTQDAPEE--VRNRDFRRELEERERAAAREKNRDRP---- 79
            ++K+    +  S    K+ +   D  EE  +   +    L+ R R     K  D+P    
Sbjct: 2154 INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKF 2213

Query: 80   --------TREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLA 131
                    + EH +    S    L++  + + + ++   +EE+ + EE  ++++      
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273

Query: 132  ELEKIKKERAEEQARKEQEQKAEEERIRMENI 163
            E E+ + E+ EE+ +K++++K +EE    E +
Sbjct: 2274 EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305



 Score = 34.3 bits (77), Expect = 0.091
 Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 4/113 (3%)

Query: 49   DAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDP 108
            D P+E     F  +++E E      +  +    E     S+S +   ++      + ++ 
Sbjct: 2207 DKPKE----KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEV 2262

Query: 109  LTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
              +EE+   EEE ++        E +K KKE+ +E+ ++++E   E+E I  E
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315


>gi|21314720 Smad nuclear interacting protein [Homo sapiens]
          Length = 396

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 17/127 (13%)

Query: 7   PTFEPARGG----------------RGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDA 50
           PT EPAR G                + K  G  S+  +   +R  P H+ +K +Q  +D 
Sbjct: 56  PTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRS-PHHSTVKVKQEREDH 114

Query: 51  PEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLT 110
           P   R     RE  E+E   AR  +RDR         + +++P   Q    + D  +   
Sbjct: 115 PRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQA 174

Query: 111 DEEDEDF 117
            EE+ +F
Sbjct: 175 QEEEREF 181


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 8/117 (6%)

Query: 48  QDAPEEVRNRDFRRELEERERAAAREKNRDR-PTREHTTSSSVSKKPRLDQIPAANLDAD 106
           Q +PEE+R R+  +E  ERE+   +E+ ++R   RE        K+  L++      + +
Sbjct: 498 QPSPEEIREREREKE-REREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556

Query: 107 DPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163
                E++++ E + + +       EL+K+K++  E +  KE+E+  E+   R  N+
Sbjct: 557 KERKQEKEKELERQKEKE------KELQKMKEQEKECELEKEREKLEEKIEPREPNL 607



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 7/102 (6%)

Query: 67  ERAAAREKNRDRPTREHTTSSSVSKKPRLDQ-------IPAANLDADDPLTDEEDEDFEE 119
           ERA  R +  +R   E   ++   K  RLD+        P+     +     E + + E 
Sbjct: 460 ERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKEL 519

Query: 120 ESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
           E + +       E ++ +++  E++  KEQE++ E E+ R +
Sbjct: 520 EKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 22/103 (21%), Positives = 50/103 (48%), Gaps = 4/103 (3%)

Query: 55  RNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEED 114
           R  +  R +EE+ +AA  EK +    R       + K+P  ++I     + +     E +
Sbjct: 465 RREEEERRMEEQRKAACAEKLK----RLDEKLGILEKQPSPEEIREREREKEREREKELE 520

Query: 115 EDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEER 157
           ++ E+E + +       + EK K+   E++ ++E E++ ++E+
Sbjct: 521 KEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK 563



 Score = 29.3 bits (64), Expect = 2.9
 Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 18/157 (11%)

Query: 81  REHTTSSSVSKKPRL--DQIPAANLDA----DDPLTDEE---DEDFEEESDDDDTAALLA 131
           +E  TSS +   P+L   Q P  +  A      P   ++   DED   +      + + A
Sbjct: 398 QERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISA 457

Query: 132 ELEKIKKERAEEQARKEQEQKA--EEERIRMENILSGNPLLNLTGPSQPQANFKVKRRWD 189
            +E+ +K R EE+ R E+++KA   E+  R++  L    L     P + +   + K R  
Sbjct: 458 AVERARKRREEEERRMEEQRKAACAEKLKRLDEKL--GILEKQPSPEEIREREREKERER 515

Query: 190 DDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEK 226
           +  + K       +Q+++K    D  R +  +K +EK
Sbjct: 516 EKELEKE-----QEQEREKEREKDRERQQEKEKELEK 547


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 3/151 (1%)

Query: 12  ARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAA 71
           +RG RG      S  S  + S +  S    + R   +D  ++ R+  F R   ER+R   
Sbjct: 575 SRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDN 634

Query: 72  REKNR--DRPTREHTTSSSVSKKPRLDQIPAANL-DADDPLTDEEDEDFEEESDDDDTAA 128
           RE+++    P R    +  + +  R ++     + D  D    E D + E + + +    
Sbjct: 635 RERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERE 694

Query: 129 LLAELEKIKKERAEEQARKEQEQKAEEERIR 159
              + E+ K+   E +  +E+E++ E+ER R
Sbjct: 695 RERDREREKERELERERAREREREREKERDR 725



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 13/165 (7%)

Query: 58  DFRRELEERERAAAREKNRDRPT-REHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDED 116
           D RR+   RER   RE++R+R   RE        K+  L++  A   + +     E D +
Sbjct: 669 DDRRDERARERDRERERDRERERERERERDREREKERELERERARERERERE--KERDRE 726

Query: 117 FEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPS 176
            + + D D       E ++ +KER  E+  +E+E++ E ER R E               
Sbjct: 727 RDRDRDHDRERERERERDR-EKEREREREERERERERERERER-ERERERERARERDKER 784

Query: 177 QPQANFKVKRRWDDDVVFK--------NCAKGVDDQKKDKRFVND 213
           + Q +++ K +  DD   K        N   G D++K  KR+ N+
Sbjct: 785 ERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829



 Score = 36.2 bits (82), Expect = 0.024
 Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 23/168 (13%)

Query: 52  EEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLT 110
           E  R+RD  RE E ERER   +E+ R+R  RE        ++   ++      + D    
Sbjct: 726 ERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERE 785

Query: 111 DEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLL 170
            + D + +++  DD         EK ++ R +   R   +++  ++R R E         
Sbjct: 786 RQRDWEDKDKGRDD-------RREKREEIREDRNPRDGHDERKSKKRYRNE--------- 829

Query: 171 NLTGPSQPQANFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSE 218
              G   P+ + K +R    D    +     DD+ +  R ++  +R +
Sbjct: 830 ---GSPSPRQSPKRRREHSPD---SDAYNSGDDKNEKHRLLSQVVRPQ 871



 Score = 35.4 bits (80), Expect = 0.041
 Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 14/126 (11%)

Query: 42   KYRQTTQDAPEE-VRNRDFRRELEERERAAAREKNRDRP-TREHTTSSSVSKKPRLDQ-- 97
            + R+  +DA ++  RNRD R  L ERER   R+K RD    RE   S SV +    D+  
Sbjct: 1319 RQREWDRDADKDWPRNRD-RDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDR 1377

Query: 98   -IPAANLDA----DDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQK 152
               ++ +++    +  L  E + D E  S D    +L  + E++ K+    Q  +E  + 
Sbjct: 1378 TFESSQIESVKRCEAKLEGEHERDLESTSRD----SLALDKERMDKDLGSVQGFEETNKS 1433

Query: 153  AEEERI 158
               E +
Sbjct: 1434 ERTESL 1439



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 39/202 (19%)

Query: 16  RGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRREL-EERERAAAREK 74
           RGKG     + S +  + DL    K K RQ     P++    +    + +E  R   REK
Sbjct: 66  RGKGYSSNYRRSPERPTGDLRERMKNK-RQDVDTEPQKRNTEESSSPVRKESSRGRHREK 124

Query: 75  NRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAAL----L 130
              + T+E T                       P ++EE+ ++E   DD D   +    +
Sbjct: 125 EDIKITKERT-----------------------PESEEENVEWETNRDDSDNGDINYDYV 161

Query: 131 AELE-KIKKERAEEQARK-EQEQKAEEERIRMENILSGNPLLNLTGPSQP-QANFKVKRR 187
            EL  ++K+++ + +  K EQE   + E I ++  +S   + +   PS   + + K  +R
Sbjct: 162 HELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKR 221

Query: 188 WDDDVVFKNCAKGVDDQKKDKR 209
                  K+  K     KKD++
Sbjct: 222 -------KSSPKSSSASKKDRK 236



 Score = 29.3 bits (64), Expect = 2.9
 Identities = 28/141 (19%), Positives = 56/141 (39%), Gaps = 7/141 (4%)

Query: 16  RGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKN 75
           RGK + +     ++   +D  S    +  +  +D  +    RD R   + RE   +R+  
Sbjct: 421 RGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDR---RDARDTRDRRELRDSRDMR 477

Query: 76  RDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEK 135
             R  R+++  +  S+ PR  +   +  DA D   D E  D   + D     +       
Sbjct: 478 DSREMRDYSRDTKESRDPRDSR---STRDAHD-YRDREGRDTHRKEDTYPEESRSYGRNH 533

Query: 136 IKKERAEEQARKEQEQKAEEE 156
           +++E +  + R E   ++  E
Sbjct: 534 LREESSRTEIRNESRNESRSE 554


>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 6/138 (4%)

Query: 27  SKQYSSRDL--PSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84
           S+ YS R     +  ++K R   +     +     R     RER  +R ++RDR T   +
Sbjct: 573 SRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRAS 632

Query: 85  TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQ 144
            S S  ++   DQ    NL  +      + E  E+E   + + ++  + +K  KER  EQ
Sbjct: 633 RSRSRDRRKIDDQ--RGNLSGNS--HKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688

Query: 145 ARKEQEQKAEEERIRMEN 162
            +++++QK EE+  +  +
Sbjct: 689 DKRKEKQKREEKDFKFSS 706


>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 6/138 (4%)

Query: 27  SKQYSSRDL--PSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84
           S+ YS R     +  ++K R   +     +     R     RER  +R ++RDR T   +
Sbjct: 573 SRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRAS 632

Query: 85  TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQ 144
            S S  ++   DQ    NL  +      + E  E+E   + + ++  + +K  KER  EQ
Sbjct: 633 RSRSRDRRKIDDQ--RGNLSGNS--HKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688

Query: 145 ARKEQEQKAEEERIRMEN 162
            +++++QK EE+  +  +
Sbjct: 689 DKRKEKQKREEKDFKFSS 706


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
          Length = 1341

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 46/155 (29%), Positives = 67/155 (43%), Gaps = 40/155 (25%)

Query: 36   PSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAA---------------REKNRDRPT 80
            P H + + R+  +   E+   R+  RE+E RER  +               R ++RDR  
Sbjct: 1128 PQHPRAEQREQERAVREQWAERE--REMERRERTRSEREWDRDKVREGPRSRSRSRDRRR 1185

Query: 81   REHTTSSSVS--KKPRLDQIPAANLDADD--------------PLTDEEDEDFEEESDDD 124
            +E   S      KK +  + P A L  DD              PLTD +    E E    
Sbjct: 1186 KERAKSKEKKSEKKEKAQEEPPAKL-LDDLFRKTKAAPCIYWLPLTDSQIVQKEAER--- 1241

Query: 125  DTAALLAELEKIKKERAEEQARKEQEQKAEEERIR 159
              A    E EK +KE+ EE+ +KE+E++AE ER R
Sbjct: 1242 --AERAKEREKRRKEQ-EEEEQKEREKEAERERNR 1273



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 4/135 (2%)

Query: 25  QLSKQYSSRDLPSHTKIKYRQTTQ---DAPEEVRNRDFRRELEERERAAAREKNRDRPTR 81
           Q S +    +L  H+  K    ++   D+ +E   +  RR    R+  AA+     +P  
Sbjct: 188 QSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAE 247

Query: 82  EHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDED-FEEESDDDDTAALLAELEKIKKER 140
           E     + S+  R+        + ++   +EE+ED  EEE DD+   +  A + K  KE 
Sbjct: 248 EEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEE 307

Query: 141 AEEQARKEQEQKAEE 155
            EE  R + E+  +E
Sbjct: 308 GEEIPRVKPEEMMDE 322



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 58  DFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDF 117
           DF+  LE  E   +R   R   +       S  +KPR  +  ++ +         E    
Sbjct: 186 DFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQP 245

Query: 118 EEESDDDDTAA--LLAELEKIKKERAEEQARKEQEQKAEEE 156
            EE +D +T +  L    ++  K   EE+  +E+E+  EEE
Sbjct: 246 AEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEE 286


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 28/105 (26%), Positives = 57/105 (54%), Gaps = 7/105 (6%)

Query: 60   RRELEERERAAAREKNRDR-PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFE 118
            + ELEE +R+  ++K R R   +E ++S + S     ++      + ++   +EE+E+ E
Sbjct: 1371 KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEE------EKEEEEEEEEEEEEE 1424

Query: 119  EESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163
            EE ++DD+ +     +KI+K   +++ R E +   +EE  R + I
Sbjct: 1425 EEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRI 1469



 Score = 34.3 bits (77), Expect = 0.091
 Identities = 27/142 (19%), Positives = 61/142 (42%), Gaps = 9/142 (6%)

Query: 24   SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEE----RERAAAREKNRDRP 79
            S    + S +    H  ++++ T  D       +   +E +E      R  + E + D  
Sbjct: 1286 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1345

Query: 80   TREHTTSSSVSK-----KPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELE 134
             +E   S  VS+     +PR      A L+ +     ++ +    +  +D ++   +  E
Sbjct: 1346 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSE 1405

Query: 135  KIKKERAEEQARKEQEQKAEEE 156
            + ++E+ EE+  +E+E++ EE+
Sbjct: 1406 EEEEEKEEEEEEEEEEEEEEED 1427


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 28/105 (26%), Positives = 57/105 (54%), Gaps = 7/105 (6%)

Query: 60   RRELEERERAAAREKNRDR-PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFE 118
            + ELEE +R+  ++K R R   +E ++S + S     ++      + ++   +EE+E+ E
Sbjct: 1409 KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEE------EKEEEEEEEEEEEEE 1462

Query: 119  EESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163
            EE ++DD+ +     +KI+K   +++ R E +   +EE  R + I
Sbjct: 1463 EEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRI 1507



 Score = 34.3 bits (77), Expect = 0.091
 Identities = 27/142 (19%), Positives = 61/142 (42%), Gaps = 9/142 (6%)

Query: 24   SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEE----RERAAAREKNRDRP 79
            S    + S +    H  ++++ T  D       +   +E +E      R  + E + D  
Sbjct: 1324 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1383

Query: 80   TREHTTSSSVSK-----KPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELE 134
             +E   S  VS+     +PR      A L+ +     ++ +    +  +D ++   +  E
Sbjct: 1384 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSE 1443

Query: 135  KIKKERAEEQARKEQEQKAEEE 156
            + ++E+ EE+  +E+E++ EE+
Sbjct: 1444 EEEEEKEEEEEEEEEEEEEEED 1465


>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
          Length = 1312

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 5/117 (4%)

Query: 40  KIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIP 99
           +IK ++  +   +E++  + R  +   E+    E  R    +E+   S  SKK  L+ IP
Sbjct: 425 EIKVKEENETEIKEIKMEEERNIIPREEKPIEDEIER----KENIKPSLGSKKNLLESIP 480

Query: 100 AANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEE 156
             + D +  +  ++ ED E   D DD    + E   IK E  EE+A+   E   EE+
Sbjct: 481 THS-DQEKEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEED 536



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 6/85 (7%)

Query: 72  REKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLA 131
           +E N  +P              R+D+     ++A++      DE  +EE +DD+      
Sbjct: 487 KEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDE------ 540

Query: 132 ELEKIKKERAEEQARKEQEQKAEEE 156
           E E+ ++E  EE+   + +   EEE
Sbjct: 541 EAEEEEEEEEEEEDEDDDDNNEEEE 565


>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
           isoform 2 [Homo sapiens]
          Length = 470

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 48/207 (23%), Positives = 88/207 (42%), Gaps = 40/207 (19%)

Query: 41  IKYRQTTQDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIP 99
           + + +  Q   EE R    RRE+E +R+R   R K ++   R+      + K  ++D+IP
Sbjct: 201 LSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKR---KDIEKLKKIDRIP 257

Query: 100 AANLDADDP---LTDEEDEDFEEESDDDDTAALL----------------------AELE 134
             +   D+P   L  + ++  E+E D  + A  L                      +EL+
Sbjct: 258 ERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELK 317

Query: 135 KIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRRWDDDVVF 194
             K +R E+++ ++  ++  E     E IL     L      Q +   + K R++ +  F
Sbjct: 318 DEKPKRPEDESGRDYREREREYERDQERILRERERLK----RQEEERRRQKERYEKEKTF 373

Query: 195 KNCAKGVDDQKKDKRFVNDTLRSEFHK 221
           K   +  ++ KK+K    DTLR +  K
Sbjct: 374 K---RKEEEMKKEK----DTLRDKGKK 393



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 5/95 (5%)

Query: 70  AAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN--LDADDPLTDEEDEDFEEESDDDDTA 127
           AA++K + R T+  T       +  L+     N  + +      EE E    E     T 
Sbjct: 139 AAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTT 198

Query: 128 ALLAEL---EKIKKERAEEQARKEQEQKAEEERIR 159
            LL+ L   +++++E+ EE+ R+E E+K + E  R
Sbjct: 199 PLLSFLKNKQRMREEKREERRRREIERKRQREEER 233



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 32/161 (19%), Positives = 62/161 (38%), Gaps = 19/161 (11%)

Query: 22  DLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTR 81
           +LS       S  LP  +  + +      PE+   RD+R    ERER   R++ R    R
Sbjct: 295 NLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYR----EREREYERDQERILRER 350

Query: 82  EHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERA 141
           E        ++ + ++         +     ++E+ ++E D           +K KK  +
Sbjct: 351 ERLKRQEEERRRQKERY------EKEKTFKRKEEEMKKEKD--------TLRDKGKKAES 396

Query: 142 EEQARKEQEQKAEEERIRMENILS-GNPLLNLTGPSQPQAN 181
            E     ++ + +EE ++ + I +   P + L  P     N
Sbjct: 397 TESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRN 437


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 4/139 (2%)

Query: 22  DLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPT- 80
           D  +  ++   RD     + +  + T+   E  R R+ +R+ + RER   R++ R R T 
Sbjct: 51  DREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTD-RERDKDRDRERKRETD 109

Query: 81  --REHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK 138
             RE        +  + ++      +       E     E + + D      AE E+ KK
Sbjct: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169

Query: 139 ERAEEQARKEQEQKAEEER 157
           ER +E+ ++ +E+K EE+R
Sbjct: 170 ERKKERKKERKEKKKEEKR 188



 Score = 35.4 bits (80), Expect = 0.041
 Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 7/128 (5%)

Query: 33  RDLPSHTKIKYRQTTQDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSK 91
           R+  + T+ + R   +D   E R+R   RE E ER++   R++ R+R T   T      +
Sbjct: 25  RERENQTERENRHRQRDRHRE-RDRQTDREKERERQKERDRQRQRERETERETERQRERQ 83

Query: 92  KPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQ 151
           + R           D     + D + + E+D +         E+ K+   E    +E+++
Sbjct: 84  RQR-----ERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR 138

Query: 152 KAEEERIR 159
           + E ER R
Sbjct: 139 QRERERQR 146


>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 28/128 (21%), Positives = 57/128 (44%)

Query: 32  SRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSK 91
           S++ P    +       D  +  R RD  RE  E+ER   R+++R+R  +E  T+ +  +
Sbjct: 56  SQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDR 115

Query: 92  KPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQ 151
           + + +       +       E D   E E D D       + EK +  + E +  +E+++
Sbjct: 116 EKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDR 175

Query: 152 KAEEERIR 159
           + E+++ R
Sbjct: 176 EREKQKER 183



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 13/114 (11%)

Query: 48  QDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTR-EHTTSSSVSKKPRLDQIPAANLDA 105
           Q   E  R+RD +R+ E ERER   RE++R R T+ E    +    +   D+      D 
Sbjct: 180 QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239

Query: 106 DDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIR 159
           D     + + D +EE   +            KKER +E+  K++E+K  E++ R
Sbjct: 240 DRGKERDRERDRKEERKKER-----------KKERKKERKEKKKEEKRREDKKR 282



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/151 (20%), Positives = 63/151 (41%), Gaps = 6/151 (3%)

Query: 12  ARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAA 71
           +RG  G  E   S    Q + +D     + + R   ++  E+ R+RD +R+ E R +   
Sbjct: 50  SRGRLGSQESPRSWGLGQ-AHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKE 108

Query: 72  REKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLA 131
             +NRDR  +     + + +    ++      + D     E D D E+E +         
Sbjct: 109 TNRNRDREKQ-----TEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDG 163

Query: 132 ELEKIKKERAEEQARKEQEQKAEEERIRMEN 162
           + E   +   + +  K++E++ E +R R  +
Sbjct: 164 QRETETERERDREREKQKERETERDRDRQRD 194



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 35/123 (28%), Positives = 51/123 (41%), Gaps = 8/123 (6%)

Query: 40  KIKYRQTTQDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQI 98
           K + RQT +D       RD +RE E ERER   REK ++R T         ++K R  Q 
Sbjct: 151 KERERQTEKD-------RDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQT 203

Query: 99  PAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERI 158
                      T+ + E   E   + D            KER  E+ RKE+ +K  ++  
Sbjct: 204 DRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKER 263

Query: 159 RME 161
           + E
Sbjct: 264 KKE 266


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 85  TSSSVSKKPRLDQIPAANLDADDPLT--DEEDEDFEEESDDDDTAALLAELEKIKKERAE 142
           TSS     P L    AA+     P +  D+ED DF+ + D+++      E+E+ ++    
Sbjct: 256 TSSKAGSSPCLGSSSAAS-SPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDA 314

Query: 143 EQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQP 178
           E  R+E E    E  + +E +L   P   L GPS P
Sbjct: 315 EAQRREIELLRREGELPLEELLRSLPPQLLEGPSSP 350



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 17/61 (27%), Positives = 34/61 (55%)

Query: 90  SKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQ 149
           +++P  +   + +   +D   DEEDE  EEE     +A+  +E E+ +  +++ QA +E+
Sbjct: 485 AEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEE 544

Query: 150 E 150
           E
Sbjct: 545 E 545



 Score = 31.6 bits (70), Expect = 0.59
 Identities = 38/158 (24%), Positives = 58/158 (36%), Gaps = 43/158 (27%)

Query: 16  RGKGEGDLSQLSKQYSSRDL-----PSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAA 70
           R +GE  L +L +    + L     PS T   +   T+D PEE    +  + LE +   +
Sbjct: 325 RREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPS 384

Query: 71  AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDF----EEESDDDDT 126
           A  +   +P                               DE+DE+F    EE  D++DT
Sbjct: 385 AVTQRNKQPWH----------------------------PDEDDEEFTANEEEAEDEEDT 416

Query: 127 AALLAELEKIKKERAEEQARKEQEQKAEEERIRMENIL 164
            A   +LE       E     E  + A E  + ME +L
Sbjct: 417 IAAEEQLE------GEVDHAMELSELAREGELSMEELL 448



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 14/71 (19%), Positives = 39/71 (54%), Gaps = 1/71 (1%)

Query: 96  DQIPAANLDADDPLTDEEDEDFEEE-SDDDDTAALLAELEKIKKERAEEQARKEQEQKAE 154
           ++ P  +  +     ++  ED E+E S++++T+   A  E   +E  + Q++ + +++ E
Sbjct: 486 EEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEE 545

Query: 155 EERIRMENILS 165
           ++   +E +L+
Sbjct: 546 DDDFGVEYLLA 556


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 28/141 (19%)

Query: 24  SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREH 83
           SQL  Q  +       +I+ RQ      E+ R ++  RE  ERER       R+R  RE 
Sbjct: 125 SQLPAQVQNGPSQEELEIQRRQLQ----EQQRQKELERERLERERMERERLERERLERER 180

Query: 84  TTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK-ERAE 142
                  ++ RL+Q                 E  E E  + +    L   E++++ ER E
Sbjct: 181 L------ERERLEQ-----------------EQLERERQERERQERLERQERLERQERLE 217

Query: 143 EQARKEQEQKAEEERIRMENI 163
            Q R ++E++  +ER R+E +
Sbjct: 218 RQERLDRERQERQERERLERL 238



 Score = 35.8 bits (81), Expect = 0.031
 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 13/149 (8%)

Query: 11  PARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAA 70
           PA+   G  + +L    +Q   +      + +  +  +   E +      RE  ERER  
Sbjct: 128 PAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLE 187

Query: 71  AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALL 130
             +  R+R  RE      + ++ RL++     L+  + L  E  E  E E         L
Sbjct: 188 QEQLERERQERER--QERLERQERLER--QERLERQERLDRERQERQERER--------L 235

Query: 131 AELEKIKKER-AEEQARKEQEQKAEEERI 158
             LE+ ++ER  +EQ  +EQ +   E RI
Sbjct: 236 ERLERERQERERQEQLEREQLEWERERRI 264


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 28/141 (19%)

Query: 24  SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREH 83
           SQL  Q  +       +I+ RQ      E+ R ++  RE  ERER       R+R  RE 
Sbjct: 125 SQLPAQVQNGPSQEELEIQRRQLQ----EQQRQKELERERLERERMERERLERERLERER 180

Query: 84  TTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK-ERAE 142
                  ++ RL+Q                 E  E E  + +    L   E++++ ER E
Sbjct: 181 L------ERERLEQ-----------------EQLERERQERERQERLERQERLERQERLE 217

Query: 143 EQARKEQEQKAEEERIRMENI 163
            Q R ++E++  +ER R+E +
Sbjct: 218 RQERLDRERQERQERERLERL 238



 Score = 35.8 bits (81), Expect = 0.031
 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 13/149 (8%)

Query: 11  PARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAA 70
           PA+   G  + +L    +Q   +      + +  +  +   E +      RE  ERER  
Sbjct: 128 PAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLE 187

Query: 71  AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALL 130
             +  R+R  RE      + ++ RL++     L+  + L  E  E  E E         L
Sbjct: 188 QEQLERERQERER--QERLERQERLER--QERLERQERLDRERQERQERER--------L 235

Query: 131 AELEKIKKER-AEEQARKEQEQKAEEERI 158
             LE+ ++ER  +EQ  +EQ +   E RI
Sbjct: 236 ERLERERQERERQEQLEREQLEWERERRI 264


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 3/124 (2%)

Query: 42  KYRQTTQDAPEEVRNRDFRRELEERERAA-AREKNRDRPTREHTTSSSVSKKPRLDQIPA 100
           K R   +   +E R R  + ELE ++R   A+    +R TR    S  +  +   ++   
Sbjct: 486 KRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQ 545

Query: 101 ANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRM 160
               A++    E +E    +   ++ A +  E E++++ER +   R+EQE+   E + R+
Sbjct: 546 LQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERL--ERKKRL 603

Query: 161 ENIL 164
           E I+
Sbjct: 604 EEIM 607



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 13/41 (31%), Positives = 26/41 (63%)

Query: 121 SDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
           +D ++   LLAE  ++ +E+ E++ R+ +EQ+  E + R E
Sbjct: 474 TDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREE 514


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 5/126 (3%)

Query: 43  YRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN 102
           Y    + A +E R     +  +ERE AAAR + R     +        K+ +L +    N
Sbjct: 605 YVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRN 664

Query: 103 LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARK-----EQEQKAEEER 157
             AD  + +EE EDF+   +  DT     + + + ++  +  + K     ++ Q   +E 
Sbjct: 665 STADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEF 724

Query: 158 IRMENI 163
            R E I
Sbjct: 725 TRQEQI 730



 Score = 32.3 bits (72), Expect = 0.35
 Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 9/88 (10%)

Query: 74  KNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAEL 133
           K RD+  ++    S   +K +L +  A  L+A      +E ED E++ ++      + E 
Sbjct: 306 KERDKLLKQEEMKSLAFEKAKLKREKADALEAKK----KEKEDKEKKREE---LKKIVEE 358

Query: 134 EKIKKERAEEQARKEQEQKAEEERIRME 161
           E++KK+  EE+ R + E++ E E++R E
Sbjct: 359 ERLKKK--EEKERLKVEREKEREKLREE 384



 Score = 28.1 bits (61), Expect = 6.5
 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 5/60 (8%)

Query: 67   ERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDT 126
            ++ + R  +R RP+ E       S     D++     D D+     E+E++E E D+DD+
Sbjct: 1166 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEV-----DGDEEEGQSEEEEYEVEQDEDDS 1220


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 5/126 (3%)

Query: 43  YRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN 102
           Y    + A +E R     +  +ERE AAAR + R     +        K+ +L +    N
Sbjct: 637 YVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRN 696

Query: 103 LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARK-----EQEQKAEEER 157
             AD  + +EE EDF+   +  DT     + + + ++  +  + K     ++ Q   +E 
Sbjct: 697 STADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEF 756

Query: 158 IRMENI 163
            R E I
Sbjct: 757 TRQEQI 762



 Score = 32.3 bits (72), Expect = 0.35
 Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 9/88 (10%)

Query: 74  KNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAEL 133
           K RD+  ++    S   +K +L +  A  L+A      +E ED E++ ++      + E 
Sbjct: 306 KERDKLLKQEEMKSLAFEKAKLKREKADALEAKK----KEKEDKEKKREE---LKKIVEE 358

Query: 134 EKIKKERAEEQARKEQEQKAEEERIRME 161
           E++KK+  EE+ R + E++ E E++R E
Sbjct: 359 ERLKKK--EEKERLKVEREKEREKLREE 384



 Score = 28.1 bits (61), Expect = 6.5
 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 5/60 (8%)

Query: 67   ERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDT 126
            ++ + R  +R RP+ E       S     D++     D D+     E+E++E E D+DD+
Sbjct: 1198 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEV-----DGDEEEGQSEEEEYEVEQDEDDS 1252


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 10/91 (10%)

Query: 111 DEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEER----IRMENI--L 164
           DEE+E+ EEE ++D+      E E+ ++E  EE+  +E+E++ EEE     I  E+    
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHT 320

Query: 165 SGNPLLNLTGPS----QPQANFKVKRRWDDD 191
           S      L GP     +P+ +  V+ R DDD
Sbjct: 321 SAQKAPELRGPESPSPKPEYSVIVEVRSDDD 351



 Score = 35.8 bits (81), Expect = 0.031
 Identities = 16/48 (33%), Positives = 32/48 (66%)

Query: 109 LTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEE 156
           L+ EE+++ EEE ++++      E E+ ++E  EE+  +E+E++ EEE
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 47/221 (21%), Positives = 93/221 (42%), Gaps = 28/221 (12%)

Query: 18   KGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVR-NRDFRRELEERERAAAREKNR 76
            + + DL  L  +   RD     + +++Q  +  PEE +  R+ ++E + R+R +  EK  
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERR-RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320

Query: 77   DRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEE-DEDFEEES--DDDDTAALLAEL 133
             R  RE       + +   ++        + PL  +E D  F EE     +     L E 
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380

Query: 134  EKIKKERAE------EQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRR 187
            ++++++  E      EQ  + QE++ +  + R          L+               R
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLS---------------R 1425

Query: 188  WDDDVVFKNCAKGVDDQKKDKRFVND--TLRSEFHKKFMEK 226
             + D  F+   + V  Q+++++F+ +   LR E H+KF E+
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 5/145 (3%)

Query: 20   EGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRE---LEERERAAAREKNR 76
            E +  QL +Q   R +    +++  +  Q    + R+R FR E    +ERE    R +  
Sbjct: 1734 ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793

Query: 77   DRPTREHTTSSSVSKKPRL--DQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELE 134
            DR  RE        ++ +L   Q        ++ L  EE E    +  D    A      
Sbjct: 1794 DRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853

Query: 135  KIKKERAEEQARKEQEQKAEEERIR 159
            + K  R E++  +E+EQK  +ER R
Sbjct: 1854 QEKSRREEQELWQEEEQKRRQERER 1878



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 4/122 (3%)

Query: 44   RQTTQDAPEEVRNRDFRRE--LEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAA 101
            R+  +    + + R +R E  L++ E    RE+   R  +E        KK +  +    
Sbjct: 915  REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974

Query: 102  NLDADDPLTDEEDEDF--EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIR 159
              + +     E ++ +  EEE   ++   L  E EK +++  E Q RK+ E + EEE++ 
Sbjct: 975  GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034

Query: 160  ME 161
             E
Sbjct: 1035 RE 1036



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 12/118 (10%)

Query: 47  TQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDAD 106
           T++ P+E + R  RREL E  R    EK + R  R+        +K    +         
Sbjct: 201 TEEFPDEEQLR--RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR--------- 249

Query: 107 DPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENIL 164
           + +  +E+E  +EE +      L  E E+++K   +E  R+ QE++ +++R+R E  L
Sbjct: 250 ETVLRKEEEKLQEE-EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 8/138 (5%)

Query: 25  QLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEER-ERAAAREKNRDRPTREH 83
           QL ++          + + +Q  ++  EE R +  RRE EER E+   RE+  +R  RE 
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER--REQ 362

Query: 84  TTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEE 143
                  ++ R  Q     L  +  L  E+    E++   +       +L + ++ R E+
Sbjct: 363 QLRREQEEERREQQ-----LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417

Query: 144 QARKEQEQKAEEERIRME 161
           Q R+EQ+ + E+E  R E
Sbjct: 418 QLRREQQLRREQEEERHE 435



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 34/220 (15%)

Query: 22   DLSQLSKQYSSRDLPSHTKIKYRQTTQDAPE--------EVRNRDFRRE---LEERERAA 70
            D  QL +Q   + L      K+R+  Q   E        + R+R F  E   L  +ER  
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659

Query: 71   AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESD----DDDT 126
                +RDR  RE        ++ +L +      + D    +EE +   +E +     ++ 
Sbjct: 1660 QLRHDRDRKFREEEQLLQEGEEQQLRR-----QERDRKFREEEQQLRRQERERKFLQEEQ 1714

Query: 127  AALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKR 186
                 ELE+  K R EEQ R+E EQ+    + R   IL    L       +P+   +  R
Sbjct: 1715 QLRRQELER--KFREEEQLRQETEQEQLRRQERYRKILEEEQL-------RPEREEQQLR 1765

Query: 187  RWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEK 226
            R + D  F+      ++Q + +R        E  +KF E+
Sbjct: 1766 RQERDRKFRE-----EEQLRQEREEQQLRSQESDRKFREE 1800



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 8/120 (6%)

Query: 45  QTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLD 104
           Q  ++   ++  ++ RRE +E E+   R +   +  R+        ++ R +Q      +
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ-----QE 326

Query: 105 ADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENIL 164
             +   +  ++    E ++     L  E E+   ER E+Q R+EQE++  E+++R E  L
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEE---ERREQQLRREQEEERREQQLRREQQL 383



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 18/129 (13%)

Query: 35  LPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPR 94
           L    +++ R+  Q   EE          E++ER  ++E+ RD+  R         ++  
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQ-----EDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888

Query: 95  LDQIPAAN--LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQK 152
           L   PA    L  +  L  EE+E+ + E           E EK +++  E Q R+E++ +
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQRE-----------EREKRRRQEQERQYREEEQLQ 937

Query: 153 AEEERIRME 161
            EEE++  E
Sbjct: 938 QEEEQLLRE 946



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 46/223 (20%), Positives = 84/223 (37%), Gaps = 38/223 (17%)

Query: 25   QLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRE---LEERERAAAREKNRDRPTR 81
            QL +Q   R      +   RQ       + R+R FR E    +ERE      + RDR  R
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582

Query: 82   ---EHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESD------------DDDT 126
               +        +K   D+      +    L  E D  F E+               +  
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642

Query: 127  AALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKR 186
               L E  +++++  E+Q R ++++K  EE    E +L              +   +  R
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREE----EQLLQ-------------EGEEQQLR 1685

Query: 187  RWDDDVVFKNCAKGVDDQKKDKRFVND---TLRSEFHKKFMEK 226
            R + D  F+   + +  Q+++++F+ +     R E  +KF E+
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 27/120 (22%), Positives = 55/120 (45%), Gaps = 5/120 (4%)

Query: 44   RQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANL 103
            ++  Q+   + R +D   EL++ E    RE+   R  +E        ++ + ++      
Sbjct: 1010 KRRRQEWERQYRKKD---ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066

Query: 104  DADDPLTDEEDEDF--EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
            + +     E +  +  EEE   ++   L  E EK +++  E Q R+E+E + EEE++  E
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 25/137 (18%)

Query: 25   QLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84
            +L +QY   +     + +  Q  ++ PE+ R ++  R+  E E     E+   R  RE  
Sbjct: 1075 ELERQYRKEE---ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131

Query: 85   TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQ 144
                + ++ R                  E+E+ ++E +      L  E EK +++  E Q
Sbjct: 1132 RRQELERQYR------------------EEEEVQQEEEQ----LLREEPEKRRRQELERQ 1169

Query: 145  ARKEQEQKAEEERIRME 161
             R+E+E + EEE++  E
Sbjct: 1170 YREEEELQQEEEQLLRE 1186



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 35/140 (25%), Positives = 59/140 (42%), Gaps = 7/140 (5%)

Query: 28   KQYSSRD-LPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTS 86
            +QY  +D L    +   R+  +    + R R +R E EE ++   +    +R TR     
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREE-EELQQEEEQLLGEERETRRRQEL 1076

Query: 87   SSVSKKPRLDQIPAANLDADDPLTDEEDEDF-----EEESDDDDTAALLAELEKIKKERA 141
                +K    Q     L  ++P      E       EEE   ++   L  E EK +++  
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136

Query: 142  EEQARKEQEQKAEEERIRME 161
            E Q R+E+E + EEE++  E
Sbjct: 1137 ERQYREEEEVQQEEEQLLRE 1156



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 41/197 (20%), Positives = 86/197 (43%), Gaps = 12/197 (6%)

Query: 42   KYRQTTQDAPEEVRNRDFRRE---LEERERAAAREKNRDRPTREHTTSSSVSKKPRL--- 95
            K+ +  Q    + R R F +E   L  +ER   R ++RDR  RE        ++ +L   
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575

Query: 96   DQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAEL--EKIKKERAEEQARKEQEQKA 153
            ++     L+       E++  F E+           +L  E+ +K R +EQ  +E+E++ 
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635

Query: 154  EEERIRMENILSGNPLLNLTGPSQPQANFKVKR-RWDDDVVFKNCAKGVDDQKKDKRFVN 212
               + R    L   P L      Q   + + ++ R ++ ++ +   + +  Q++D++F  
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695

Query: 213  D---TLRSEFHKKFMEK 226
            +     R E  +KF+++
Sbjct: 1696 EEQQLRRQERERKFLQE 1712



 Score = 35.8 bits (81), Expect = 0.031
 Identities = 29/143 (20%), Positives = 65/143 (45%), Gaps = 15/143 (10%)

Query: 28  KQYSSRDLPSHTK---IKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84
           KQ   RD     +   +K  +  +   +E R +  RRE EER     + +  +   ++  
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532

Query: 85  TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDD----DTAALLAELEKIKKER 140
            S    ++ + ++        +  L  EE++  E+E  +     +      +L K ++ER
Sbjct: 533 RSEQQLRREQEER-------REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585

Query: 141 AEEQARKEQEQKAEEERIRMENI 163
            +++ ++EQE++  E+R++ E +
Sbjct: 586 RQQRLKREQEERL-EQRLKREEV 607



 Score = 35.4 bits (80), Expect = 0.041
 Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 12/128 (9%)

Query: 44  RQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANL 103
           RQ  +   + +R     R  +E ER   +E+ R++  R         ++ R +Q      
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR-- 347

Query: 104 DADDPLTDEEDEDFEE-----ESDDDDTAALLAELEKIKKE---RAEEQARKEQEQKAEE 155
             +  L  E++E+  E     E +++     L   +++++E   R E+Q R+EQ+ + E+
Sbjct: 348 --EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405

Query: 156 ERIRMENI 163
           +  R + +
Sbjct: 406 QLRREQQL 413



 Score = 35.4 bits (80), Expect = 0.041
 Identities = 33/181 (18%), Positives = 77/181 (42%), Gaps = 17/181 (9%)

Query: 40  KIKYRQTTQDAPEEVRN-RDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQI 98
           ++K ++  +   + +R+ +  RRE EER     + +   R  +E           R  ++
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER----------REQRL 567

Query: 99  PAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEE-ER 157
                +  D L   E+E  ++    +    L   L++ + ER E++ R+EQ  K EE E 
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627

Query: 158 IRMENILSGNP-----LLNLTGPSQPQANFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVN 212
            R + +L            L    Q +   ++KR  +++ + +   +  +++++++    
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687

Query: 213 D 213
           +
Sbjct: 688 E 688



 Score = 35.4 bits (80), Expect = 0.041
 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 14/127 (11%)

Query: 42   KYRQTTQDAPEEVRNRDFRRE---LEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQI 98
            K+ +  Q   +E R+R FR E   L+ERE      + RDR   E      + ++ R  + 
Sbjct: 1447 KFLEEEQQLRQE-RHRKFREEEQLLQEREEQQLHRQERDRKFLEE--EQQLRRQERDRKF 1503

Query: 99   PAANLDADDPLTDEEDEDFEEESD---DDDTAALLAELEKIKKERAEEQARKEQEQK-AE 154
                L + +P    E +  EEE            L E ++++++   +Q R+++++K  E
Sbjct: 1504 REQELRSQEP----ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE 1559

Query: 155  EERIRME 161
            EE++R E
Sbjct: 1560 EEQLRQE 1566



 Score = 35.0 bits (79), Expect = 0.053
 Identities = 29/115 (25%), Positives = 50/115 (43%), Gaps = 8/115 (6%)

Query: 55  RNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEE 113
           R +  RRE +  RE+   RE+  +R  ++H       +  R  +     L  ++     E
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468

Query: 114 DEDF-------EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
            E         +EE   +    L  E  + ++ER E+Q R+EQE++ E+   R E
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523



 Score = 34.7 bits (78), Expect = 0.070
 Identities = 29/123 (23%), Positives = 56/123 (45%), Gaps = 26/123 (21%)

Query: 48  QDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADD 107
           Q   +E R +  +RE EER     RE+  +R  +E        +K +L +          
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQER-------RKQQLKR---------- 478

Query: 108 PLTDEEDE------DFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
              D+E+E        EEE   +       +L + ++ER E++ ++++E++  ++R+R E
Sbjct: 479 ---DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535

Query: 162 NIL 164
             L
Sbjct: 536 QQL 538



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 27/145 (18%), Positives = 63/145 (43%), Gaps = 1/145 (0%)

Query: 20  EGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEER-ERAAAREKNRDR 78
           E  L +L +Q   R+     + + R   +      +  + R + EER E+   RE+  +R
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334

Query: 79  PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK 138
             ++        ++ +L +             ++E+E  E++   +       +L + ++
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394

Query: 139 ERAEEQARKEQEQKAEEERIRMENI 163
            R E+Q R+EQ+ + E++  R + +
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQL 419



 Score = 32.3 bits (72), Expect = 0.35
 Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 10/127 (7%)

Query: 42  KYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAA 101
           + ++  ++  E +  R  R E+E  E+   RE+   R   E      + K    ++    
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645

Query: 102 NLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
            L  +     E+    EEE +  +        +++K+E  EE  R+EQE   EE+    E
Sbjct: 646 QLRREQQERREQRLKREEEEERLE--------QRLKREHEEE--RREQELAEEEQEQARE 695

Query: 162 NILSGNP 168
            I S  P
Sbjct: 696 RIKSRIP 702



 Score = 31.2 bits (69), Expect = 0.77
 Identities = 27/127 (21%), Positives = 53/127 (41%), Gaps = 11/127 (8%)

Query: 48  QDAPEEVRNRDFR---RELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLD 104
           QD  +E   R F    R+LEE      R+K +++            K+ RL+Q      D
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170

Query: 105 ADDPLTDEEDEDFEEESDDDD--------TAALLAELEKIKKERAEEQARKEQEQKAEEE 156
            +     +E ++ EE   +++              + E++++    E  RK +E+K ++ 
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230

Query: 157 RIRMENI 163
           R R + +
Sbjct: 231 RERQDRV 237



 Score = 29.3 bits (64), Expect = 2.9
 Identities = 26/122 (21%), Positives = 48/122 (39%), Gaps = 4/122 (3%)

Query: 42   KYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAA 101
            +YR+  +   EE +     RE   R+    + +  +   +E         + R  Q    
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108

Query: 102  NLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
                ++ L  EE++   EE +         ELE+  +E  E Q  +EQ  + E E+ R +
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQ----ELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164

Query: 162  NI 163
             +
Sbjct: 1165 EL 1166



 Score = 28.5 bits (62), Expect = 5.0
 Identities = 30/168 (17%), Positives = 64/168 (38%), Gaps = 20/168 (11%)

Query: 25   QLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84
            +L +QY   +     + +  Q  ++ PE+ R ++  R+  E E     E+   R  +E  
Sbjct: 1135 ELERQYREEE---EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191

Query: 85   TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQ 144
                  +    +++             +  +  +   D+D  + L  + E  K+    + 
Sbjct: 1192 RQERERQYREEEEL-------------QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238

Query: 145  A----RKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRRW 188
                  +E EQ  + E  ++ +  S   L +L G  Q +   + +RRW
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286


>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
          Length = 334

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 30/181 (16%)

Query: 16  RGKGEGDLSQLSKQYS----SRDLP---SHTKIKYRQTTQDAPEEVRNRDFRRELEERER 68
           RG+G+    Q S+  S    SR  P   SH++   R + +      R+R+ R+  ++ +R
Sbjct: 88  RGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERRKGRDKEKR 147

Query: 69  AAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN-------------LDADDPL-TDEED 114
              ++K +D+         S + K  L+ +P A                AD+ L   E +
Sbjct: 148 EKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKERN 207

Query: 115 EDFEEESDDDDTAALLAELEKIKKERAEE---------QARKEQEQKAEEERIRMENILS 165
           E+  +   ++D A L+ +++++K+  A E         ++ KE ++  E   ++     S
Sbjct: 208 EEEAKRRKEEDQATLVEQVKRVKEIEAIESDSFVQQTFRSSKEVKKSVEPSEVKQATSTS 267

Query: 166 G 166
           G
Sbjct: 268 G 268


>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 9/110 (8%)

Query: 52  EEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTD 111
           EE  +    +E +  ER     K R +   + T    VSK P          D    L D
Sbjct: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE---------DKKKRLED 62

Query: 112 EEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
           ++ +  ++E    D   + AE E  KKE  E++  +E+E+K +EE+ + +
Sbjct: 63  DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 43/187 (22%), Positives = 84/187 (44%), Gaps = 26/187 (13%)

Query: 61  RELEERERAAAREKNRDR---PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDF 117
           ++  ER   +++E+ +D      ++  + +   KK RL+       D +    DEE    
Sbjct: 23  KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA 82

Query: 118 EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKA------EEERIRM-------ENIL 164
           EEES   +        E+ +K++ EEQA+++QE++A      +EE I++        ++ 
Sbjct: 83  EEESKKKEEEEKKKHQEEERKKQ-EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLR 141

Query: 165 SGNPLLNLTGP-SQPQANF--KVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHK 221
                 N   P S+P+ NF  ++      +  F    K + +Q++      D+L  +F+ 
Sbjct: 142 KELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR------DSLSHDFNG 195

Query: 222 KFMEKYI 228
             + KYI
Sbjct: 196 LNLSKYI 202



 Score = 27.7 bits (60), Expect = 8.5
 Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 2/66 (3%)

Query: 104  DADDPLTDEE--DEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
            D+ D +T+ E  +ED EEE    +T        ++ +   EE +  + ++  EEE    +
Sbjct: 1018 DSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTD 1077

Query: 162  NILSGN 167
             +   N
Sbjct: 1078 YLTDSN 1083


>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 9/110 (8%)

Query: 52  EEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTD 111
           EE  +    +E +  ER     K R +   + T    VSK P          D    L D
Sbjct: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE---------DKKKRLED 62

Query: 112 EEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
           ++ +  ++E    D   + AE E  KKE  E++  +E+E+K +EE+ + +
Sbjct: 63  DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 43/187 (22%), Positives = 84/187 (44%), Gaps = 26/187 (13%)

Query: 61  RELEERERAAAREKNRDR---PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDF 117
           ++  ER   +++E+ +D      ++  + +   KK RL+       D +    DEE    
Sbjct: 23  KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA 82

Query: 118 EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKA------EEERIRM-------ENIL 164
           EEES   +        E+ +K++ EEQA+++QE++A      +EE I++        ++ 
Sbjct: 83  EEESKKKEEEEKKKHQEEERKKQ-EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLR 141

Query: 165 SGNPLLNLTGP-SQPQANF--KVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHK 221
                 N   P S+P+ NF  ++      +  F    K + +Q++      D+L  +F+ 
Sbjct: 142 KELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR------DSLSHDFNG 195

Query: 222 KFMEKYI 228
             + KYI
Sbjct: 196 LNLSKYI 202



 Score = 27.7 bits (60), Expect = 8.5
 Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 2/66 (3%)

Query: 104  DADDPLTDEE--DEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161
            D+ D +T+ E  +ED EEE    +T        ++ +   EE +  + ++  EEE    +
Sbjct: 1018 DSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTD 1077

Query: 162  NILSGN 167
             +   N
Sbjct: 1078 YLTDSN 1083


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 30/165 (18%), Positives = 72/165 (43%), Gaps = 27/165 (16%)

Query: 45  QTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLD 104
           +++Q + EEV + ++  + E     ++ E+  +    E      V +   +++    + +
Sbjct: 165 RSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE 224

Query: 105 ADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENIL 164
            D+   +EE+E+ EEE ++++            +E   EQ  ++Q+++  +   R E   
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEE------------EEEEYEQDERDQKEEGNDYDTRSEASD 272

Query: 165 SGNPLLNLTGPSQPQANFKVKRRWDDDVVFKNCAKGVDDQKKDKR 209
           SG+  ++ T               D  V   +   G D++KK+++
Sbjct: 273 SGSESVSFT---------------DGSVRSGSGTDGSDEKKKERK 302



 Score = 36.6 bits (83), Expect = 0.018
 Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 10/140 (7%)

Query: 23  LSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAA------REKNR 76
           LS  + +   ++ P  T ++ R   + A     +   R  LE   RA+        E N 
Sbjct: 117 LSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNS 176

Query: 77  DRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKI 136
           +    +H T SS S   + +         ++ +  EEDE+ EE++++D+      E E+ 
Sbjct: 177 EEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV--EEDEEVEEDAEEDEEVDEDGEEEE- 233

Query: 137 KKERAEEQARKEQEQKAEEE 156
            +E  EE+  +E+E++  E+
Sbjct: 234 -EEEEEEEEEEEEEEEEYEQ 252


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,336,858
Number of Sequences: 37866
Number of extensions: 476465
Number of successful extensions: 11935
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 428
Number of HSP's successfully gapped in prelim test: 635
Number of HSP's that attempted gapping in prelim test: 5130
Number of HSP's gapped (non-prelim): 4048
length of query: 229
length of database: 18,247,518
effective HSP length: 99
effective length of query: 130
effective length of database: 14,498,784
effective search space: 1884841920
effective search space used: 1884841920
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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