BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116812573 CWC15 homolog [Homo sapiens] (229 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116812573 CWC15 homolog [Homo sapiens] 459 e-130 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 58 8e-09 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 50 2e-06 gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 49 5e-06 gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 49 5e-06 gi|221219020 NYD-SP11 protein [Homo sapiens] 48 8e-06 gi|21314720 Smad nuclear interacting protein [Homo sapiens] 45 7e-05 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 45 7e-05 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 45 7e-05 gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 44 9e-05 gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 44 9e-05 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 44 1e-04 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 44 2e-04 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 44 2e-04 gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 43 3e-04 gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso... 42 3e-04 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 42 4e-04 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 42 6e-04 gi|56549694 enabled homolog isoform a [Homo sapiens] 41 7e-04 gi|39930375 enabled homolog isoform b [Homo sapiens] 41 7e-04 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 41 7e-04 gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 41 7e-04 gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 41 7e-04 gi|17975763 myelin transcription factor 1 [Homo sapiens] 41 0.001 gi|148746195 trichohyalin [Homo sapiens] 41 0.001 gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 41 0.001 gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 41 0.001 gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 41 0.001 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 41 0.001 >gi|116812573 CWC15 homolog [Homo sapiens] Length = 229 Score = 459 bits (1181), Expect = e-130 Identities = 229/229 (100%), Positives = 229/229 (100%) Query: 1 MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFR 60 MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFR Sbjct: 1 MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFR 60 Query: 61 RELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEE 120 RELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEE Sbjct: 61 RELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEE 120 Query: 121 SDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQA 180 SDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQA Sbjct: 121 SDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQA 180 Query: 181 NFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK 229 NFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK Sbjct: 181 NFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK 229 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 57.8 bits (138), Expect = 8e-09 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 3/141 (2%) Query: 22 DLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRR---ELEERERAAAREKNRDR 78 D++ + + RDL S K+R T + EE ++ R E E RER RE+ R+R Sbjct: 263 DINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER 322 Query: 79 PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK 138 RE ++ ++ D D T E D D + E D D ++ K + Sbjct: 323 REREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS 382 Query: 139 ERAEEQARKEQEQKAEEERIR 159 E+ +E+E++ E ER R Sbjct: 383 RSREKSRDRERERERERERER 403 Score = 42.0 bits (97), Expect = 4e-04 Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 7/133 (5%) Query: 40 KIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIP 99 K K R +D + R R+L E+E AA +E+ ++ RE + K+ ++ Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKE-AAYQERLKNWEIRERKKTREYEKEAEREEER 485 Query: 100 AANLDADDPLTDEEDEDFEEESDDDD---TAALLAELEKIKKE-RAEEQARKEQEQKAEE 155 + + E ED++++ DD +AL L +KE A+E+ RK ++++ EE Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEE 545 Query: 156 ERIRMENILSGNP 168 IR + G+P Sbjct: 546 --IRQRLLAEGHP 556 Score = 41.2 bits (95), Expect = 7e-04 Identities = 37/161 (22%), Positives = 73/161 (45%), Gaps = 13/161 (8%) Query: 6 RPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELE- 64 R T + +GK E + ++ K+ R+ + + R+ ++ E R R+ +E E Sbjct: 285 RDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERE-REREKEKERER 343 Query: 65 --ERERAAAREKNRDRP-TREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEES 121 ER+R R K RDR RE D+ +++ + D + E+ D E E Sbjct: 344 ERERDRDRDRTKERDRDRDRERDRDR--------DRERSSDRNKDRSRSREKSRDRERER 395 Query: 122 DDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMEN 162 + + E E+ ++ E + +E+E++ +++R R E+ Sbjct: 396 EREREREREREREREREREREREREREREREKDKKRDREED 436 Score = 33.1 bits (74), Expect = 0.20 Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 17/136 (12%) Query: 40 KIKYRQTTQDAPEEVRNRDFRRELEE-RERAAAREKNRDRPT-REHTTSSSVSKKPRLDQ 97 + K R +D E R+RD R + ++R+ +REK+RDR RE ++ ++ Sbjct: 353 RTKERDRDRDR-ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411 Query: 98 IPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARK---------- 147 + + E+D+ + E D++D K++++ A Q R Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKK 471 Query: 148 ----EQEQKAEEERIR 159 E+E + EEER R Sbjct: 472 TREYEKEAEREEERRR 487 Score = 33.1 bits (74), Expect = 0.20 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 13/110 (11%) Query: 48 QDAPEEVRNRDFRRELEERERAA-AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDAD 106 +D P+ R ++ L +RE+ A E++R R +K L++I L Sbjct: 507 RDDPKYYRGSALQKRLRDREKEMEADERDRKR------------EKEELEEIRQRLLAEG 554 Query: 107 DPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEE 156 P D E + E+E++ + E E ++E +++ +++E+ EEE Sbjct: 555 HPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604 Score = 32.0 bits (71), Expect = 0.45 Identities = 30/120 (25%), Positives = 54/120 (45%), Gaps = 3/120 (2%) Query: 44 RQTTQDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN 102 R+ ++D E R R+ RE E ERER RE+ R+R RE + D+ A Sbjct: 385 REKSRDRERE-RERERERERERERERERERERERER-EREREREKDKKRDREEDEEDAYE 442 Query: 103 LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMEN 162 + E++ ++E + + E K+ EE+ R+E ++A+ + +E+ Sbjct: 443 RRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED 502 Score = 31.2 bits (69), Expect = 0.77 Identities = 37/129 (28%), Positives = 55/129 (42%), Gaps = 21/129 (16%) Query: 52 EEVRNRD--FRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQI----PAANLDA 105 EE + RD + +E R + E N P++E + KK + + I P A L Sbjct: 198 EETKRRDQMIKGAIEVLIREYSSELNA--PSQESDSHPRKKKKEKKEDIFRRFPVAPLIP 255 Query: 106 DDPLTDEEDEDFEEESDDDDTAAL----------LAELEKIKKERAE---EQARKEQEQK 152 +T E+ E E D D + E EK KKE+ E+ R+E+E++ Sbjct: 256 YPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERE 315 Query: 153 AEEERIRME 161 E ER R E Sbjct: 316 RERERERRE 324 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 50.1 bits (118), Expect = 2e-06 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 6/121 (4%) Query: 48 QDAPEEVRNRD-----FRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN 102 Q EE+ R+ R+ EER R A+E+ ++R +EH + + RL+QI Sbjct: 588 QREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTE 647 Query: 103 LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMEN 162 L A D + ED EE D A + +LEK KKE E +E++ E R+E Sbjct: 648 LGA-KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEE 706 Query: 163 I 163 I Sbjct: 707 I 707 Score = 32.0 bits (71), Expect = 0.45 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 12/122 (9%) Query: 48 QDAPEEVRNRDFRRE--LEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDA 105 Q E + RE LE + R + ++RD + + +L Q Sbjct: 727 QQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQF------- 779 Query: 106 DDPLTDEEDEDFEE---ESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMEN 162 ++ L +E EE + ++ E E+ ++ RAEEQ KE+E++ ER + E Sbjct: 780 EERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREE 839 Query: 163 IL 164 L Sbjct: 840 EL 841 Score = 30.4 bits (67), Expect = 1.3 Identities = 34/143 (23%), Positives = 63/143 (44%), Gaps = 7/143 (4%) Query: 24 SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREH 83 +++S+ RDL ++ + Q EE + R EER R + R R +E Sbjct: 748 NRMSRMLEDRDL---FVMRLKAARQSVYEEKLKQFEERLAEERHN---RLEERKRQRKEE 801 Query: 84 TTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKI-KKERAE 142 + +K +Q A + E E + E + + + +LE++ +K+R Sbjct: 802 RRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQR 861 Query: 143 EQARKEQEQKAEEERIRMENILS 165 E +E+E++ EEER ++ LS Sbjct: 862 ELEIEERERRREEERRLGDSSLS 884 Score = 30.4 bits (67), Expect = 1.3 Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 12/131 (9%) Query: 40 KIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIP 99 K K R+ + P E R EERE +E++RD RE K P ++ Sbjct: 1181 KEKAREESWGPPRE------SRPSEEREWDREKERDRDNQDREEN-----DKDPERERDR 1229 Query: 100 AANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEER-I 158 ++D +D DE +++++ + ++R + + ++ + E R + Sbjct: 1230 ERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDL 1289 Query: 159 RMENILSGNPL 169 R + G PL Sbjct: 1290 RDDRDRRGPPL 1300 Score = 28.5 bits (62), Expect = 5.0 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 23/115 (20%) Query: 44 RQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANL 103 R+ +D + R RD RR+L ER R P R + VS R D + Sbjct: 1264 RRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLR--SEREEVSSWRRADDRKDDRV 1321 Query: 104 DADDP--------LTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQE 150 + DP L+ + + D + E + + KE+A +A K++E Sbjct: 1322 EERDPPRRVPPPALSRDRERDRDREREGE-------------KEKASWRAEKDRE 1363 Score = 27.7 bits (60), Expect = 8.5 Identities = 11/29 (37%), Positives = 21/29 (72%) Query: 133 LEKIKKERAEEQARKEQEQKAEEERIRME 161 +++ K+E + +A ++ +KAEEER+R E Sbjct: 587 IQREKEELEQREAELQKVRKAEEERLRQE 615 >gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo sapiens] Length = 1108 Score = 48.5 bits (114), Expect = 5e-06 Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 13/104 (12%) Query: 60 RRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEE 119 +RE EER+ E + + EH + + + + D + LT EEDED E+ Sbjct: 971 KREAEERDSTEQEEAGPEILSNEHVGARASPSQ--------GDSDERESLTREEDEDSEK 1022 Query: 120 ESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163 E +++D E+E++++E+ E+ + ++E++ EEE + E + Sbjct: 1023 EEEEED-----KEMEELQEEKECEKPQGDEEEEEEEEEVEEEEV 1061 Score = 30.0 bits (66), Expect = 1.7 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 21/106 (19%) Query: 64 EERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDD 123 +ERE + RE++ D E + + + + P DEE+E+ EEE ++ Sbjct: 1007 DERE-SLTREEDEDSEKEEEEEDKEMEELQE-------EKECEKPQGDEEEEEEEEEVEE 1058 Query: 124 DDTAALLAELEKIKKE------RAEEQAR-------KEQEQKAEEE 156 ++ E E+ K E RAE QA + EQ +EE+ Sbjct: 1059 EEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEK 1104 >gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo sapiens] Length = 1124 Score = 48.5 bits (114), Expect = 5e-06 Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 13/104 (12%) Query: 60 RRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEE 119 +RE EER+ E + + EH + + + + D + LT EEDED E+ Sbjct: 987 KREAEERDSTEQEEAGPEILSNEHVGARASPSQ--------GDSDERESLTREEDEDSEK 1038 Query: 120 ESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163 E +++D E+E++++E+ E+ + ++E++ EEE + E + Sbjct: 1039 EEEEED-----KEMEELQEEKECEKPQGDEEEEEEEEEVEEEEV 1077 Score = 30.0 bits (66), Expect = 1.7 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 21/106 (19%) Query: 64 EERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDD 123 +ERE + RE++ D E + + + + P DEE+E+ EEE ++ Sbjct: 1023 DERE-SLTREEDEDSEKEEEEEDKEMEELQE-------EKECEKPQGDEEEEEEEEEVEE 1074 Query: 124 DDTAALLAELEKIKKE------RAEEQAR-------KEQEQKAEEE 156 ++ E E+ K E RAE QA + EQ +EE+ Sbjct: 1075 EEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEK 1120 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 47.8 bits (112), Expect = 8e-06 Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 9/151 (5%) Query: 20 EGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRP 79 E L +L KQ S L S + + + + EEVR + R+ EE EK ++ Sbjct: 2231 ESLLDELEKQES---LSSEEEEEREEEEEREEEEVREEEEERKEEEE----GEEKQVEKE 2283 Query: 80 TREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKE 139 E KK + + + ++ +++EE E +E +++++ +L E+++ K+ Sbjct: 2284 EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEI 2343 Query: 140 RAEEQARKEQEQ--KAEEERIRMENILSGNP 168 +E+ K QEQ K+ R R+ +IL G P Sbjct: 2344 LKKEKQFKLQEQRRKSLRGRERVLSILRGVP 2374 Score = 38.9 bits (89), Expect = 0.004 Identities = 19/55 (34%), Positives = 33/55 (60%) Query: 107 DPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 + + + DE EE ++ +LL ELEK + +EE+ +E+E++ EEE +R E Sbjct: 2211 EKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265 Score = 37.0 bits (84), Expect = 0.014 Identities = 30/152 (19%), Positives = 67/152 (44%), Gaps = 14/152 (9%) Query: 26 LSKQYSSRDLPSHTKIKYRQTTQDAPEE--VRNRDFRRELEERERAAAREKNRDRP---- 79 ++K+ + S K+ + D EE + + L+ R R K D+P Sbjct: 2154 INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKF 2213 Query: 80 --------TREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLA 131 + EH + S L++ + + + ++ +EE+ + EE ++++ Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273 Query: 132 ELEKIKKERAEEQARKEQEQKAEEERIRMENI 163 E E+ + E+ EE+ +K++++K +EE E + Sbjct: 2274 EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305 Score = 34.3 bits (77), Expect = 0.091 Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 4/113 (3%) Query: 49 DAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDP 108 D P+E F +++E E + + E S+S + ++ + ++ Sbjct: 2207 DKPKE----KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEV 2262 Query: 109 LTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 +EE+ EEE ++ E +K KKE+ +E+ ++++E E+E I E Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315 >gi|21314720 Smad nuclear interacting protein [Homo sapiens] Length = 396 Score = 44.7 bits (104), Expect = 7e-05 Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 17/127 (13%) Query: 7 PTFEPARGG----------------RGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDA 50 PT EPAR G + K G S+ + +R P H+ +K +Q +D Sbjct: 56 PTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRS-PHHSTVKVKQEREDH 114 Query: 51 PEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLT 110 P R RE E+E AR +RDR + +++P Q + D + Sbjct: 115 PRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQA 174 Query: 111 DEEDEDF 117 EE+ +F Sbjct: 175 QEEEREF 181 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 44.7 bits (104), Expect = 7e-05 Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 8/117 (6%) Query: 48 QDAPEEVRNRDFRRELEERERAAAREKNRDR-PTREHTTSSSVSKKPRLDQIPAANLDAD 106 Q +PEE+R R+ +E ERE+ +E+ ++R RE K+ L++ + + Sbjct: 498 QPSPEEIREREREKE-REREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556 Query: 107 DPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163 E++++ E + + + EL+K+K++ E + KE+E+ E+ R N+ Sbjct: 557 KERKQEKEKELERQKEKE------KELQKMKEQEKECELEKEREKLEEKIEPREPNL 607 Score = 33.9 bits (76), Expect = 0.12 Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 7/102 (6%) Query: 67 ERAAAREKNRDRPTREHTTSSSVSKKPRLDQ-------IPAANLDADDPLTDEEDEDFEE 119 ERA R + +R E ++ K RLD+ P+ + E + + E Sbjct: 460 ERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKEL 519 Query: 120 ESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 E + + E ++ +++ E++ KEQE++ E E+ R + Sbjct: 520 EKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561 Score = 33.5 bits (75), Expect = 0.16 Identities = 22/103 (21%), Positives = 50/103 (48%), Gaps = 4/103 (3%) Query: 55 RNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEED 114 R + R +EE+ +AA EK + R + K+P ++I + + E + Sbjct: 465 RREEEERRMEEQRKAACAEKLK----RLDEKLGILEKQPSPEEIREREREKEREREKELE 520 Query: 115 EDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEER 157 ++ E+E + + + EK K+ E++ ++E E++ ++E+ Sbjct: 521 KEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK 563 Score = 29.3 bits (64), Expect = 2.9 Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 18/157 (11%) Query: 81 REHTTSSSVSKKPRL--DQIPAANLDA----DDPLTDEE---DEDFEEESDDDDTAALLA 131 +E TSS + P+L Q P + A P ++ DED + + + A Sbjct: 398 QERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISA 457 Query: 132 ELEKIKKERAEEQARKEQEQKA--EEERIRMENILSGNPLLNLTGPSQPQANFKVKRRWD 189 +E+ +K R EE+ R E+++KA E+ R++ L L P + + + K R Sbjct: 458 AVERARKRREEEERRMEEQRKAACAEKLKRLDEKL--GILEKQPSPEEIREREREKERER 515 Query: 190 DDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEK 226 + + K +Q+++K D R + +K +EK Sbjct: 516 EKELEKE-----QEQEREKEREKDRERQQEKEKELEK 547 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 44.7 bits (104), Expect = 7e-05 Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 3/151 (1%) Query: 12 ARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAA 71 +RG RG S S + S + S + R +D ++ R+ F R ER+R Sbjct: 575 SRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDN 634 Query: 72 REKNR--DRPTREHTTSSSVSKKPRLDQIPAANL-DADDPLTDEEDEDFEEESDDDDTAA 128 RE+++ P R + + + R ++ + D D E D + E + + + Sbjct: 635 RERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERE 694 Query: 129 LLAELEKIKKERAEEQARKEQEQKAEEERIR 159 + E+ K+ E + +E+E++ E+ER R Sbjct: 695 RERDREREKERELERERAREREREREKERDR 725 Score = 40.0 bits (92), Expect = 0.002 Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 13/165 (7%) Query: 58 DFRRELEERERAAAREKNRDRPT-REHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDED 116 D RR+ RER RE++R+R RE K+ L++ A + + E D + Sbjct: 669 DDRRDERARERDRERERDRERERERERERDREREKERELERERARERERERE--KERDRE 726 Query: 117 FEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPS 176 + + D D E ++ +KER E+ +E+E++ E ER R E Sbjct: 727 RDRDRDHDRERERERERDR-EKEREREREERERERERERERER-ERERERERARERDKER 784 Query: 177 QPQANFKVKRRWDDDVVFK--------NCAKGVDDQKKDKRFVND 213 + Q +++ K + DD K N G D++K KR+ N+ Sbjct: 785 ERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829 Score = 36.2 bits (82), Expect = 0.024 Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 23/168 (13%) Query: 52 EEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLT 110 E R+RD RE E ERER +E+ R+R RE ++ ++ + D Sbjct: 726 ERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERE 785 Query: 111 DEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLL 170 + D + +++ DD EK ++ R + R +++ ++R R E Sbjct: 786 RQRDWEDKDKGRDD-------RREKREEIREDRNPRDGHDERKSKKRYRNE--------- 829 Query: 171 NLTGPSQPQANFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSE 218 G P+ + K +R D + DD+ + R ++ +R + Sbjct: 830 ---GSPSPRQSPKRRREHSPD---SDAYNSGDDKNEKHRLLSQVVRPQ 871 Score = 35.4 bits (80), Expect = 0.041 Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 14/126 (11%) Query: 42 KYRQTTQDAPEE-VRNRDFRRELEERERAAAREKNRDRP-TREHTTSSSVSKKPRLDQ-- 97 + R+ +DA ++ RNRD R L ERER R+K RD RE S SV + D+ Sbjct: 1319 RQREWDRDADKDWPRNRD-RDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDR 1377 Query: 98 -IPAANLDA----DDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQK 152 ++ +++ + L E + D E S D +L + E++ K+ Q +E + Sbjct: 1378 TFESSQIESVKRCEAKLEGEHERDLESTSRD----SLALDKERMDKDLGSVQGFEETNKS 1433 Query: 153 AEEERI 158 E + Sbjct: 1434 ERTESL 1439 Score = 32.7 bits (73), Expect = 0.26 Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 39/202 (19%) Query: 16 RGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRREL-EERERAAAREK 74 RGKG + S + + DL K K RQ P++ + + +E R REK Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNK-RQDVDTEPQKRNTEESSSPVRKESSRGRHREK 124 Query: 75 NRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAAL----L 130 + T+E T P ++EE+ ++E DD D + + Sbjct: 125 EDIKITKERT-----------------------PESEEENVEWETNRDDSDNGDINYDYV 161 Query: 131 AELE-KIKKERAEEQARK-EQEQKAEEERIRMENILSGNPLLNLTGPSQP-QANFKVKRR 187 EL ++K+++ + + K EQE + E I ++ +S + + PS + + K +R Sbjct: 162 HELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKR 221 Query: 188 WDDDVVFKNCAKGVDDQKKDKR 209 K+ K KKD++ Sbjct: 222 -------KSSPKSSSASKKDRK 236 Score = 29.3 bits (64), Expect = 2.9 Identities = 28/141 (19%), Positives = 56/141 (39%), Gaps = 7/141 (4%) Query: 16 RGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKN 75 RGK + + ++ +D S + + +D + RD R + RE +R+ Sbjct: 421 RGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDR---RDARDTRDRRELRDSRDMR 477 Query: 76 RDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEK 135 R R+++ + S+ PR + + DA D D E D + D + Sbjct: 478 DSREMRDYSRDTKESRDPRDSR---STRDAHD-YRDREGRDTHRKEDTYPEESRSYGRNH 533 Query: 136 IKKERAEEQARKEQEQKAEEE 156 +++E + + R E ++ E Sbjct: 534 LREESSRTEIRNESRNESRSE 554 >gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens] Length = 805 Score = 44.3 bits (103), Expect = 9e-05 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 6/138 (4%) Query: 27 SKQYSSRDL--PSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84 S+ YS R + ++K R + + R RER +R ++RDR T + Sbjct: 573 SRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRAS 632 Query: 85 TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQ 144 S S ++ DQ NL + + E E+E + + ++ + +K KER EQ Sbjct: 633 RSRSRDRRKIDDQ--RGNLSGNS--HKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688 Query: 145 ARKEQEQKAEEERIRMEN 162 +++++QK EE+ + + Sbjct: 689 DKRKEKQKREEKDFKFSS 706 >gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens] Length = 805 Score = 44.3 bits (103), Expect = 9e-05 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 6/138 (4%) Query: 27 SKQYSSRDL--PSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84 S+ YS R + ++K R + + R RER +R ++RDR T + Sbjct: 573 SRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRAS 632 Query: 85 TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQ 144 S S ++ DQ NL + + E E+E + + ++ + +K KER EQ Sbjct: 633 RSRSRDRRKIDDQ--RGNLSGNS--HKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688 Query: 145 ARKEQEQKAEEERIRMEN 162 +++++QK EE+ + + Sbjct: 689 DKRKEKQKREEKDFKFSS 706 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 43.9 bits (102), Expect = 1e-04 Identities = 46/155 (29%), Positives = 67/155 (43%), Gaps = 40/155 (25%) Query: 36 PSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAA---------------REKNRDRPT 80 P H + + R+ + E+ R+ RE+E RER + R ++RDR Sbjct: 1128 PQHPRAEQREQERAVREQWAERE--REMERRERTRSEREWDRDKVREGPRSRSRSRDRRR 1185 Query: 81 REHTTSSSVS--KKPRLDQIPAANLDADD--------------PLTDEEDEDFEEESDDD 124 +E S KK + + P A L DD PLTD + E E Sbjct: 1186 KERAKSKEKKSEKKEKAQEEPPAKL-LDDLFRKTKAAPCIYWLPLTDSQIVQKEAER--- 1241 Query: 125 DTAALLAELEKIKKERAEEQARKEQEQKAEEERIR 159 A E EK +KE+ EE+ +KE+E++AE ER R Sbjct: 1242 --AERAKEREKRRKEQ-EEEEQKEREKEAERERNR 1273 Score = 41.2 bits (95), Expect = 7e-04 Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 4/135 (2%) Query: 25 QLSKQYSSRDLPSHTKIKYRQTTQ---DAPEEVRNRDFRRELEERERAAAREKNRDRPTR 81 Q S + +L H+ K ++ D+ +E + RR R+ AA+ +P Sbjct: 188 QSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAE 247 Query: 82 EHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDED-FEEESDDDDTAALLAELEKIKKER 140 E + S+ R+ + ++ +EE+ED EEE DD+ + A + K KE Sbjct: 248 EEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEE 307 Query: 141 AEEQARKEQEQKAEE 155 EE R + E+ +E Sbjct: 308 GEEIPRVKPEEMMDE 322 Score = 33.9 bits (76), Expect = 0.12 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 2/101 (1%) Query: 58 DFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDF 117 DF+ LE E +R R + S +KPR + ++ + E Sbjct: 186 DFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQP 245 Query: 118 EEESDDDDTAA--LLAELEKIKKERAEEQARKEQEQKAEEE 156 EE +D +T + L ++ K EE+ +E+E+ EEE Sbjct: 246 AEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEE 286 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 43.5 bits (101), Expect = 2e-04 Identities = 28/105 (26%), Positives = 57/105 (54%), Gaps = 7/105 (6%) Query: 60 RRELEERERAAAREKNRDR-PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFE 118 + ELEE +R+ ++K R R +E ++S + S ++ + ++ +EE+E+ E Sbjct: 1371 KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEE------EKEEEEEEEEEEEEE 1424 Query: 119 EESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163 EE ++DD+ + +KI+K +++ R E + +EE R + I Sbjct: 1425 EEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRI 1469 Score = 34.3 bits (77), Expect = 0.091 Identities = 27/142 (19%), Positives = 61/142 (42%), Gaps = 9/142 (6%) Query: 24 SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEE----RERAAAREKNRDRP 79 S + S + H ++++ T D + +E +E R + E + D Sbjct: 1286 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1345 Query: 80 TREHTTSSSVSK-----KPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELE 134 +E S VS+ +PR A L+ + ++ + + +D ++ + E Sbjct: 1346 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSE 1405 Query: 135 KIKKERAEEQARKEQEQKAEEE 156 + ++E+ EE+ +E+E++ EE+ Sbjct: 1406 EEEEEKEEEEEEEEEEEEEEED 1427 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 43.5 bits (101), Expect = 2e-04 Identities = 28/105 (26%), Positives = 57/105 (54%), Gaps = 7/105 (6%) Query: 60 RRELEERERAAAREKNRDR-PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFE 118 + ELEE +R+ ++K R R +E ++S + S ++ + ++ +EE+E+ E Sbjct: 1409 KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEE------EKEEEEEEEEEEEEE 1462 Query: 119 EESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENI 163 EE ++DD+ + +KI+K +++ R E + +EE R + I Sbjct: 1463 EEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRI 1507 Score = 34.3 bits (77), Expect = 0.091 Identities = 27/142 (19%), Positives = 61/142 (42%), Gaps = 9/142 (6%) Query: 24 SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEE----RERAAAREKNRDRP 79 S + S + H ++++ T D + +E +E R + E + D Sbjct: 1324 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1383 Query: 80 TREHTTSSSVSK-----KPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELE 134 +E S VS+ +PR A L+ + ++ + + +D ++ + E Sbjct: 1384 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSE 1443 Query: 135 KIKKERAEEQARKEQEQKAEEE 156 + ++E+ EE+ +E+E++ EE+ Sbjct: 1444 EEEEEKEEEEEEEEEEEEEEED 1465 >gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] Length = 1312 Score = 42.7 bits (99), Expect = 3e-04 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 5/117 (4%) Query: 40 KIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIP 99 +IK ++ + +E++ + R + E+ E R +E+ S SKK L+ IP Sbjct: 425 EIKVKEENETEIKEIKMEEERNIIPREEKPIEDEIER----KENIKPSLGSKKNLLESIP 480 Query: 100 AANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEE 156 + D + + ++ ED E D DD + E IK E EE+A+ E EE+ Sbjct: 481 THS-DQEKEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEED 536 Score = 33.1 bits (74), Expect = 0.20 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 6/85 (7%) Query: 72 REKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLA 131 +E N +P R+D+ ++A++ DE +EE +DD+ Sbjct: 487 KEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDE------ 540 Query: 132 ELEKIKKERAEEQARKEQEQKAEEE 156 E E+ ++E EE+ + + EEE Sbjct: 541 EAEEEEEEEEEEEDEDDDDNNEEEE 565 >gi|12711674 UPF3 regulator of nonsense transcripts homolog B isoform 2 [Homo sapiens] Length = 470 Score = 42.4 bits (98), Expect = 3e-04 Identities = 48/207 (23%), Positives = 88/207 (42%), Gaps = 40/207 (19%) Query: 41 IKYRQTTQDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIP 99 + + + Q EE R RRE+E +R+R R K ++ R+ + K ++D+IP Sbjct: 201 LSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKR---KDIEKLKKIDRIP 257 Query: 100 AANLDADDP---LTDEEDEDFEEESDDDDTAALL----------------------AELE 134 + D+P L + ++ E+E D + A L +EL+ Sbjct: 258 ERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELK 317 Query: 135 KIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRRWDDDVVF 194 K +R E+++ ++ ++ E E IL L Q + + K R++ + F Sbjct: 318 DEKPKRPEDESGRDYREREREYERDQERILRERERLK----RQEEERRRQKERYEKEKTF 373 Query: 195 KNCAKGVDDQKKDKRFVNDTLRSEFHK 221 K + ++ KK+K DTLR + K Sbjct: 374 K---RKEEEMKKEK----DTLRDKGKK 393 Score = 29.6 bits (65), Expect = 2.2 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 5/95 (5%) Query: 70 AAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN--LDADDPLTDEEDEDFEEESDDDDTA 127 AA++K + R T+ T + L+ N + + EE E E T Sbjct: 139 AAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTT 198 Query: 128 ALLAEL---EKIKKERAEEQARKEQEQKAEEERIR 159 LL+ L +++++E+ EE+ R+E E+K + E R Sbjct: 199 PLLSFLKNKQRMREEKREERRRREIERKRQREEER 233 Score = 29.6 bits (65), Expect = 2.2 Identities = 32/161 (19%), Positives = 62/161 (38%), Gaps = 19/161 (11%) Query: 22 DLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTR 81 +LS S LP + + + PE+ RD+R ERER R++ R R Sbjct: 295 NLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYR----EREREYERDQERILRER 350 Query: 82 EHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERA 141 E ++ + ++ + ++E+ ++E D +K KK + Sbjct: 351 ERLKRQEEERRRQKERY------EKEKTFKRKEEEMKKEKD--------TLRDKGKKAES 396 Query: 142 EEQARKEQEQKAEEERIRMENILS-GNPLLNLTGPSQPQAN 181 E ++ + +EE ++ + I + P + L P N Sbjct: 397 TESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRN 437 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 42.0 bits (97), Expect = 4e-04 Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 4/139 (2%) Query: 22 DLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPT- 80 D + ++ RD + + + T+ E R R+ +R+ + RER R++ R R T Sbjct: 51 DREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTD-RERDKDRDRERKRETD 109 Query: 81 --REHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK 138 RE + + ++ + E E + + D AE E+ KK Sbjct: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169 Query: 139 ERAEEQARKEQEQKAEEER 157 ER +E+ ++ +E+K EE+R Sbjct: 170 ERKKERKKERKEKKKEEKR 188 Score = 35.4 bits (80), Expect = 0.041 Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 7/128 (5%) Query: 33 RDLPSHTKIKYRQTTQDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSK 91 R+ + T+ + R +D E R+R RE E ER++ R++ R+R T T + Sbjct: 25 RERENQTERENRHRQRDRHRE-RDRQTDREKERERQKERDRQRQRERETERETERQRERQ 83 Query: 92 KPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQ 151 + R D + D + + E+D + E+ K+ E +E+++ Sbjct: 84 RQR-----ERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR 138 Query: 152 KAEEERIR 159 + E ER R Sbjct: 139 QRERERQR 146 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 41.6 bits (96), Expect = 6e-04 Identities = 28/128 (21%), Positives = 57/128 (44%) Query: 32 SRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSK 91 S++ P + D + R RD RE E+ER R+++R+R +E T+ + + Sbjct: 56 SQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDR 115 Query: 92 KPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQ 151 + + + + E D E E D D + EK + + E + +E+++ Sbjct: 116 EKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDR 175 Query: 152 KAEEERIR 159 + E+++ R Sbjct: 176 EREKQKER 183 Score = 40.8 bits (94), Expect = 0.001 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 13/114 (11%) Query: 48 QDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTR-EHTTSSSVSKKPRLDQIPAANLDA 105 Q E R+RD +R+ E ERER RE++R R T+ E + + D+ D Sbjct: 180 QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239 Query: 106 DDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIR 159 D + + D +EE + KKER +E+ K++E+K E++ R Sbjct: 240 DRGKERDRERDRKEERKKER-----------KKERKKERKEKKKEEKRREDKKR 282 Score = 39.3 bits (90), Expect = 0.003 Identities = 31/151 (20%), Positives = 63/151 (41%), Gaps = 6/151 (3%) Query: 12 ARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAA 71 +RG G E S Q + +D + + R ++ E+ R+RD +R+ E R + Sbjct: 50 SRGRLGSQESPRSWGLGQ-AHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKE 108 Query: 72 REKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLA 131 +NRDR + + + + ++ + D E D D E+E + Sbjct: 109 TNRNRDREKQ-----TEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDG 163 Query: 132 ELEKIKKERAEEQARKEQEQKAEEERIRMEN 162 + E + + + K++E++ E +R R + Sbjct: 164 QRETETERERDREREKQKERETERDRDRQRD 194 Score = 38.1 bits (87), Expect = 0.006 Identities = 35/123 (28%), Positives = 51/123 (41%), Gaps = 8/123 (6%) Query: 40 KIKYRQTTQDAPEEVRNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQI 98 K + RQT +D RD +RE E ERER REK ++R T ++K R Q Sbjct: 151 KERERQTEKD-------RDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQT 203 Query: 99 PAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERI 158 T+ + E E + D KER E+ RKE+ +K ++ Sbjct: 204 DRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKER 263 Query: 159 RME 161 + E Sbjct: 264 KKE 266 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 41.6 bits (96), Expect = 6e-04 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 85 TSSSVSKKPRLDQIPAANLDADDPLT--DEEDEDFEEESDDDDTAALLAELEKIKKERAE 142 TSS P L AA+ P + D+ED DF+ + D+++ E+E+ ++ Sbjct: 256 TSSKAGSSPCLGSSSAAS-SPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDA 314 Query: 143 EQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQP 178 E R+E E E + +E +L P L GPS P Sbjct: 315 EAQRREIELLRREGELPLEELLRSLPPQLLEGPSSP 350 Score = 32.7 bits (73), Expect = 0.26 Identities = 17/61 (27%), Positives = 34/61 (55%) Query: 90 SKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQ 149 +++P + + + +D DEEDE EEE +A+ +E E+ + +++ QA +E+ Sbjct: 485 AEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEE 544 Query: 150 E 150 E Sbjct: 545 E 545 Score = 31.6 bits (70), Expect = 0.59 Identities = 38/158 (24%), Positives = 58/158 (36%), Gaps = 43/158 (27%) Query: 16 RGKGEGDLSQLSKQYSSRDL-----PSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAA 70 R +GE L +L + + L PS T + T+D PEE + + LE + + Sbjct: 325 RREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPS 384 Query: 71 AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDF----EEESDDDDT 126 A + +P DE+DE+F EE D++DT Sbjct: 385 AVTQRNKQPWH----------------------------PDEDDEEFTANEEEAEDEEDT 416 Query: 127 AALLAELEKIKKERAEEQARKEQEQKAEEERIRMENIL 164 A +LE E E + A E + ME +L Sbjct: 417 IAAEEQLE------GEVDHAMELSELAREGELSMEELL 448 Score = 29.6 bits (65), Expect = 2.2 Identities = 14/71 (19%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Query: 96 DQIPAANLDADDPLTDEEDEDFEEE-SDDDDTAALLAELEKIKKERAEEQARKEQEQKAE 154 ++ P + + ++ ED E+E S++++T+ A E +E + Q++ + +++ E Sbjct: 486 EEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEE 545 Query: 155 EERIRMENILS 165 ++ +E +L+ Sbjct: 546 DDDFGVEYLLA 556 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 41.2 bits (95), Expect = 7e-04 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 28/141 (19%) Query: 24 SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREH 83 SQL Q + +I+ RQ E+ R ++ RE ERER R+R RE Sbjct: 125 SQLPAQVQNGPSQEELEIQRRQLQ----EQQRQKELERERLERERMERERLERERLERER 180 Query: 84 TTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK-ERAE 142 ++ RL+Q E E E + + L E++++ ER E Sbjct: 181 L------ERERLEQ-----------------EQLERERQERERQERLERQERLERQERLE 217 Query: 143 EQARKEQEQKAEEERIRMENI 163 Q R ++E++ +ER R+E + Sbjct: 218 RQERLDRERQERQERERLERL 238 Score = 35.8 bits (81), Expect = 0.031 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 13/149 (8%) Query: 11 PARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAA 70 PA+ G + +L +Q + + + + + E + RE ERER Sbjct: 128 PAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLE 187 Query: 71 AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALL 130 + R+R RE + ++ RL++ L+ + L E E E E L Sbjct: 188 QEQLERERQERER--QERLERQERLER--QERLERQERLDRERQERQERER--------L 235 Query: 131 AELEKIKKER-AEEQARKEQEQKAEEERI 158 LE+ ++ER +EQ +EQ + E RI Sbjct: 236 ERLERERQERERQEQLEREQLEWERERRI 264 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 41.2 bits (95), Expect = 7e-04 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 28/141 (19%) Query: 24 SQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREH 83 SQL Q + +I+ RQ E+ R ++ RE ERER R+R RE Sbjct: 125 SQLPAQVQNGPSQEELEIQRRQLQ----EQQRQKELERERLERERMERERLERERLERER 180 Query: 84 TTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK-ERAE 142 ++ RL+Q E E E + + L E++++ ER E Sbjct: 181 L------ERERLEQ-----------------EQLERERQERERQERLERQERLERQERLE 217 Query: 143 EQARKEQEQKAEEERIRMENI 163 Q R ++E++ +ER R+E + Sbjct: 218 RQERLDRERQERQERERLERL 238 Score = 35.8 bits (81), Expect = 0.031 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 13/149 (8%) Query: 11 PARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAA 70 PA+ G + +L +Q + + + + + E + RE ERER Sbjct: 128 PAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLE 187 Query: 71 AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALL 130 + R+R RE + ++ RL++ L+ + L E E E E L Sbjct: 188 QEQLERERQERER--QERLERQERLER--QERLERQERLDRERQERQERER--------L 235 Query: 131 AELEKIKKER-AEEQARKEQEQKAEEERI 158 LE+ ++ER +EQ +EQ + E RI Sbjct: 236 ERLERERQERERQEQLEREQLEWERERRI 264 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 41.2 bits (95), Expect = 7e-04 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 3/124 (2%) Query: 42 KYRQTTQDAPEEVRNRDFRRELEERERAA-AREKNRDRPTREHTTSSSVSKKPRLDQIPA 100 K R + +E R R + ELE ++R A+ +R TR S + + ++ Sbjct: 486 KRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQ 545 Query: 101 ANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRM 160 A++ E +E + ++ A + E E++++ER + R+EQE+ E + R+ Sbjct: 546 LQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERL--ERKKRL 603 Query: 161 ENIL 164 E I+ Sbjct: 604 EEIM 607 Score = 30.0 bits (66), Expect = 1.7 Identities = 13/41 (31%), Positives = 26/41 (63%) Query: 121 SDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 +D ++ LLAE ++ +E+ E++ R+ +EQ+ E + R E Sbjct: 474 TDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREE 514 >gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b [Homo sapiens] Length = 1524 Score = 41.2 bits (95), Expect = 7e-04 Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 5/126 (3%) Query: 43 YRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN 102 Y + A +E R + +ERE AAAR + R + K+ +L + N Sbjct: 605 YVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRN 664 Query: 103 LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARK-----EQEQKAEEER 157 AD + +EE EDF+ + DT + + + ++ + + K ++ Q +E Sbjct: 665 STADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEF 724 Query: 158 IRMENI 163 R E I Sbjct: 725 TRQEQI 730 Score = 32.3 bits (72), Expect = 0.35 Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 9/88 (10%) Query: 74 KNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAEL 133 K RD+ ++ S +K +L + A L+A +E ED E++ ++ + E Sbjct: 306 KERDKLLKQEEMKSLAFEKAKLKREKADALEAKK----KEKEDKEKKREE---LKKIVEE 358 Query: 134 EKIKKERAEEQARKEQEQKAEEERIRME 161 E++KK+ EE+ R + E++ E E++R E Sbjct: 359 ERLKKK--EEKERLKVEREKEREKLREE 384 Score = 28.1 bits (61), Expect = 6.5 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 5/60 (8%) Query: 67 ERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDT 126 ++ + R +R RP+ E S D++ D D+ E+E++E E D+DD+ Sbjct: 1166 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEV-----DGDEEEGQSEEEEYEVEQDEDDS 1220 >gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a [Homo sapiens] Length = 1556 Score = 41.2 bits (95), Expect = 7e-04 Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 5/126 (3%) Query: 43 YRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN 102 Y + A +E R + +ERE AAAR + R + K+ +L + N Sbjct: 637 YVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRN 696 Query: 103 LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARK-----EQEQKAEEER 157 AD + +EE EDF+ + DT + + + ++ + + K ++ Q +E Sbjct: 697 STADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEF 756 Query: 158 IRMENI 163 R E I Sbjct: 757 TRQEQI 762 Score = 32.3 bits (72), Expect = 0.35 Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 9/88 (10%) Query: 74 KNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAEL 133 K RD+ ++ S +K +L + A L+A +E ED E++ ++ + E Sbjct: 306 KERDKLLKQEEMKSLAFEKAKLKREKADALEAKK----KEKEDKEKKREE---LKKIVEE 358 Query: 134 EKIKKERAEEQARKEQEQKAEEERIRME 161 E++KK+ EE+ R + E++ E E++R E Sbjct: 359 ERLKKK--EEKERLKVEREKEREKLREE 384 Score = 28.1 bits (61), Expect = 6.5 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 5/60 (8%) Query: 67 ERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDT 126 ++ + R +R RP+ E S D++ D D+ E+E++E E D+DD+ Sbjct: 1198 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEV-----DGDEEEGQSEEEEYEVEQDEDDS 1252 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 40.8 bits (94), Expect = 0.001 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 10/91 (10%) Query: 111 DEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEER----IRMENI--L 164 DEE+E+ EEE ++D+ E E+ ++E EE+ +E+E++ EEE I E+ Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHT 320 Query: 165 SGNPLLNLTGPS----QPQANFKVKRRWDDD 191 S L GP +P+ + V+ R DDD Sbjct: 321 SAQKAPELRGPESPSPKPEYSVIVEVRSDDD 351 Score = 35.8 bits (81), Expect = 0.031 Identities = 16/48 (33%), Positives = 32/48 (66%) Query: 109 LTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEE 156 L+ EE+++ EEE ++++ E E+ ++E EE+ +E+E++ EEE Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 40.8 bits (94), Expect = 0.001 Identities = 47/221 (21%), Positives = 93/221 (42%), Gaps = 28/221 (12%) Query: 18 KGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVR-NRDFRRELEERERAAAREKNR 76 + + DL L + RD + +++Q + PEE + R+ ++E + R+R + EK Sbjct: 1262 QSQQDLQHLLGEQQERDREQERR-RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320 Query: 77 DRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEE-DEDFEEES--DDDDTAALLAEL 133 R RE + + ++ + PL +E D F EE + L E Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380 Query: 134 EKIKKERAE------EQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRR 187 ++++++ E EQ + QE++ + + R L+ R Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLS---------------R 1425 Query: 188 WDDDVVFKNCAKGVDDQKKDKRFVND--TLRSEFHKKFMEK 226 + D F+ + V Q+++++F+ + LR E H+KF E+ Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466 Score = 40.4 bits (93), Expect = 0.001 Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 5/145 (3%) Query: 20 EGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRE---LEERERAAAREKNR 76 E + QL +Q R + +++ + Q + R+R FR E +ERE R + Sbjct: 1734 ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793 Query: 77 DRPTREHTTSSSVSKKPRL--DQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELE 134 DR RE ++ +L Q ++ L EE E + D A Sbjct: 1794 DRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853 Query: 135 KIKKERAEEQARKEQEQKAEEERIR 159 + K R E++ +E+EQK +ER R Sbjct: 1854 QEKSRREEQELWQEEEQKRRQERER 1878 Score = 40.0 bits (92), Expect = 0.002 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 4/122 (3%) Query: 44 RQTTQDAPEEVRNRDFRRE--LEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAA 101 R+ + + + R +R E L++ E RE+ R +E KK + + Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974 Query: 102 NLDADDPLTDEEDEDF--EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIR 159 + + E ++ + EEE ++ L E EK +++ E Q RK+ E + EEE++ Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034 Query: 160 ME 161 E Sbjct: 1035 RE 1036 Score = 39.7 bits (91), Expect = 0.002 Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 12/118 (10%) Query: 47 TQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDAD 106 T++ P+E + R RREL E R EK + R R+ +K + Sbjct: 201 TEEFPDEEQLR--RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR--------- 249 Query: 107 DPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENIL 164 + + +E+E +EE + L E E+++K +E R+ QE++ +++R+R E L Sbjct: 250 ETVLRKEEEKLQEE-EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306 Score = 39.7 bits (91), Expect = 0.002 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 8/138 (5%) Query: 25 QLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEER-ERAAAREKNRDRPTREH 83 QL ++ + + +Q ++ EE R + RRE EER E+ RE+ +R RE Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER--REQ 362 Query: 84 TTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEE 143 ++ R Q L + L E+ E++ + +L + ++ R E+ Sbjct: 363 QLRREQEEERREQQ-----LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417 Query: 144 QARKEQEQKAEEERIRME 161 Q R+EQ+ + E+E R E Sbjct: 418 QLRREQQLRREQEEERHE 435 Score = 39.7 bits (91), Expect = 0.002 Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 34/220 (15%) Query: 22 DLSQLSKQYSSRDLPSHTKIKYRQTTQDAPE--------EVRNRDFRRE---LEERERAA 70 D QL +Q + L K+R+ Q E + R+R F E L +ER Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659 Query: 71 AREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESD----DDDT 126 +RDR RE ++ +L + + D +EE + +E + ++ Sbjct: 1660 QLRHDRDRKFREEEQLLQEGEEQQLRR-----QERDRKFREEEQQLRRQERERKFLQEEQ 1714 Query: 127 AALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKR 186 ELE+ K R EEQ R+E EQ+ + R IL L +P+ + R Sbjct: 1715 QLRRQELER--KFREEEQLRQETEQEQLRRQERYRKILEEEQL-------RPEREEQQLR 1765 Query: 187 RWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEK 226 R + D F+ ++Q + +R E +KF E+ Sbjct: 1766 RQERDRKFRE-----EEQLRQEREEQQLRSQESDRKFREE 1800 Score = 39.3 bits (90), Expect = 0.003 Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 8/120 (6%) Query: 45 QTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLD 104 Q ++ ++ ++ RRE +E E+ R + + R+ ++ R +Q + Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ-----QE 326 Query: 105 ADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENIL 164 + + ++ E ++ L E E+ ER E+Q R+EQE++ E+++R E L Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEE---ERREQQLRREQEEERREQQLRREQQL 383 Score = 39.3 bits (90), Expect = 0.003 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 18/129 (13%) Query: 35 LPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPR 94 L +++ R+ Q EE E++ER ++E+ RD+ R ++ Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQ-----EDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888 Query: 95 LDQIPAAN--LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQK 152 L PA L + L EE+E+ + E E EK +++ E Q R+E++ + Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQRE-----------EREKRRRQEQERQYREEEQLQ 937 Query: 153 AEEERIRME 161 EEE++ E Sbjct: 938 QEEEQLLRE 946 Score = 39.3 bits (90), Expect = 0.003 Identities = 46/223 (20%), Positives = 84/223 (37%), Gaps = 38/223 (17%) Query: 25 QLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRE---LEERERAAAREKNRDRPTR 81 QL +Q R + RQ + R+R FR E +ERE + RDR R Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582 Query: 82 ---EHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESD------------DDDT 126 + +K D+ + L E D F E+ + Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642 Query: 127 AALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKR 186 L E +++++ E+Q R ++++K EE E +L + + R Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREE----EQLLQ-------------EGEEQQLR 1685 Query: 187 RWDDDVVFKNCAKGVDDQKKDKRFVND---TLRSEFHKKFMEK 226 R + D F+ + + Q+++++F+ + R E +KF E+ Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728 Score = 38.9 bits (89), Expect = 0.004 Identities = 27/120 (22%), Positives = 55/120 (45%), Gaps = 5/120 (4%) Query: 44 RQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANL 103 ++ Q+ + R +D EL++ E RE+ R +E ++ + ++ Sbjct: 1010 KRRRQEWERQYRKKD---ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066 Query: 104 DADDPLTDEEDEDF--EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 + + E + + EEE ++ L E EK +++ E Q R+E+E + EEE++ E Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126 Score = 38.9 bits (89), Expect = 0.004 Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 25/137 (18%) Query: 25 QLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84 +L +QY + + + Q ++ PE+ R ++ R+ E E E+ R RE Sbjct: 1075 ELERQYRKEE---ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131 Query: 85 TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQ 144 + ++ R E+E+ ++E + L E EK +++ E Q Sbjct: 1132 RRQELERQYR------------------EEEEVQQEEEQ----LLREEPEKRRRQELERQ 1169 Query: 145 ARKEQEQKAEEERIRME 161 R+E+E + EEE++ E Sbjct: 1170 YREEEELQQEEEQLLRE 1186 Score = 38.5 bits (88), Expect = 0.005 Identities = 35/140 (25%), Positives = 59/140 (42%), Gaps = 7/140 (5%) Query: 28 KQYSSRD-LPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTS 86 +QY +D L + R+ + + R R +R E EE ++ + +R TR Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREE-EELQQEEEQLLGEERETRRRQEL 1076 Query: 87 SSVSKKPRLDQIPAANLDADDPLTDEEDEDF-----EEESDDDDTAALLAELEKIKKERA 141 +K Q L ++P E EEE ++ L E EK +++ Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136 Query: 142 EEQARKEQEQKAEEERIRME 161 E Q R+E+E + EEE++ E Sbjct: 1137 ERQYREEEEVQQEEEQLLRE 1156 Score = 37.0 bits (84), Expect = 0.014 Identities = 41/197 (20%), Positives = 86/197 (43%), Gaps = 12/197 (6%) Query: 42 KYRQTTQDAPEEVRNRDFRRE---LEERERAAAREKNRDRPTREHTTSSSVSKKPRL--- 95 K+ + Q + R R F +E L +ER R ++RDR RE ++ +L Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575 Query: 96 DQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAEL--EKIKKERAEEQARKEQEQKA 153 ++ L+ E++ F E+ +L E+ +K R +EQ +E+E++ Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635 Query: 154 EEERIRMENILSGNPLLNLTGPSQPQANFKVKR-RWDDDVVFKNCAKGVDDQKKDKRFVN 212 + R L P L Q + + ++ R ++ ++ + + + Q++D++F Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695 Query: 213 D---TLRSEFHKKFMEK 226 + R E +KF+++ Sbjct: 1696 EEQQLRRQERERKFLQE 1712 Score = 35.8 bits (81), Expect = 0.031 Identities = 29/143 (20%), Positives = 65/143 (45%), Gaps = 15/143 (10%) Query: 28 KQYSSRDLPSHTK---IKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84 KQ RD + +K + + +E R + RRE EER + + + ++ Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532 Query: 85 TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDD----DTAALLAELEKIKKER 140 S ++ + ++ + L EE++ E+E + + +L K ++ER Sbjct: 533 RSEQQLRREQEER-------REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585 Query: 141 AEEQARKEQEQKAEEERIRMENI 163 +++ ++EQE++ E+R++ E + Sbjct: 586 RQQRLKREQEERL-EQRLKREEV 607 Score = 35.4 bits (80), Expect = 0.041 Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 12/128 (9%) Query: 44 RQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANL 103 RQ + + +R R +E ER +E+ R++ R ++ R +Q Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR-- 347 Query: 104 DADDPLTDEEDEDFEE-----ESDDDDTAALLAELEKIKKE---RAEEQARKEQEQKAEE 155 + L E++E+ E E +++ L +++++E R E+Q R+EQ+ + E+ Sbjct: 348 --EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405 Query: 156 ERIRMENI 163 + R + + Sbjct: 406 QLRREQQL 413 Score = 35.4 bits (80), Expect = 0.041 Identities = 33/181 (18%), Positives = 77/181 (42%), Gaps = 17/181 (9%) Query: 40 KIKYRQTTQDAPEEVRN-RDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQI 98 ++K ++ + + +R+ + RRE EER + + R +E R ++ Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER----------REQRL 567 Query: 99 PAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEE-ER 157 + D L E+E ++ + L L++ + ER E++ R+EQ K EE E Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627 Query: 158 IRMENILSGNP-----LLNLTGPSQPQANFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVN 212 R + +L L Q + ++KR +++ + + + +++++++ Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687 Query: 213 D 213 + Sbjct: 688 E 688 Score = 35.4 bits (80), Expect = 0.041 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 14/127 (11%) Query: 42 KYRQTTQDAPEEVRNRDFRRE---LEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQI 98 K+ + Q +E R+R FR E L+ERE + RDR E + ++ R + Sbjct: 1447 KFLEEEQQLRQE-RHRKFREEEQLLQEREEQQLHRQERDRKFLEE--EQQLRRQERDRKF 1503 Query: 99 PAANLDADDPLTDEEDEDFEEESD---DDDTAALLAELEKIKKERAEEQARKEQEQK-AE 154 L + +P E + EEE L E ++++++ +Q R+++++K E Sbjct: 1504 REQELRSQEP----ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE 1559 Query: 155 EERIRME 161 EE++R E Sbjct: 1560 EEQLRQE 1566 Score = 35.0 bits (79), Expect = 0.053 Identities = 29/115 (25%), Positives = 50/115 (43%), Gaps = 8/115 (6%) Query: 55 RNRDFRRELE-ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEE 113 R + RRE + RE+ RE+ +R ++H + R + L ++ E Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468 Query: 114 DEDF-------EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 E +EE + L E + ++ER E+Q R+EQE++ E+ R E Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523 Score = 34.7 bits (78), Expect = 0.070 Identities = 29/123 (23%), Positives = 56/123 (45%), Gaps = 26/123 (21%) Query: 48 QDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADD 107 Q +E R + +RE EER RE+ +R +E +K +L + Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQER-------RKQQLKR---------- 478 Query: 108 PLTDEEDE------DFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 D+E+E EEE + +L + ++ER E++ ++++E++ ++R+R E Sbjct: 479 ---DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535 Query: 162 NIL 164 L Sbjct: 536 QQL 538 Score = 33.9 bits (76), Expect = 0.12 Identities = 27/145 (18%), Positives = 63/145 (43%), Gaps = 1/145 (0%) Query: 20 EGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEER-ERAAAREKNRDR 78 E L +L +Q R+ + + R + + + R + EER E+ RE+ +R Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334 Query: 79 PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKK 138 ++ ++ +L + ++E+E E++ + +L + ++ Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394 Query: 139 ERAEEQARKEQEQKAEEERIRMENI 163 R E+Q R+EQ+ + E++ R + + Sbjct: 395 LRREQQLRREQQLRREQQLRREQQL 419 Score = 32.3 bits (72), Expect = 0.35 Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 10/127 (7%) Query: 42 KYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAA 101 + ++ ++ E + R R E+E E+ RE+ R E + K ++ Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645 Query: 102 NLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 L + E+ EEE + + +++K+E EE R+EQE EE+ E Sbjct: 646 QLRREQQERREQRLKREEEEERLE--------QRLKREHEEE--RREQELAEEEQEQARE 695 Query: 162 NILSGNP 168 I S P Sbjct: 696 RIKSRIP 702 Score = 31.2 bits (69), Expect = 0.77 Identities = 27/127 (21%), Positives = 53/127 (41%), Gaps = 11/127 (8%) Query: 48 QDAPEEVRNRDFR---RELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLD 104 QD +E R F R+LEE R+K +++ K+ RL+Q D Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170 Query: 105 ADDPLTDEEDEDFEEESDDDD--------TAALLAELEKIKKERAEEQARKEQEQKAEEE 156 + +E ++ EE +++ + E++++ E RK +E+K ++ Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230 Query: 157 RIRMENI 163 R R + + Sbjct: 231 RERQDRV 237 Score = 29.3 bits (64), Expect = 2.9 Identities = 26/122 (21%), Positives = 48/122 (39%), Gaps = 4/122 (3%) Query: 42 KYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAA 101 +YR+ + EE + RE R+ + + + +E + R Q Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108 Query: 102 NLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 ++ L EE++ EE + ELE+ +E E Q +EQ + E E+ R + Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQ----ELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164 Query: 162 NI 163 + Sbjct: 1165 EL 1166 Score = 28.5 bits (62), Expect = 5.0 Identities = 30/168 (17%), Positives = 64/168 (38%), Gaps = 20/168 (11%) Query: 25 QLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHT 84 +L +QY + + + Q ++ PE+ R ++ R+ E E E+ R +E Sbjct: 1135 ELERQYREEE---EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191 Query: 85 TSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQ 144 + +++ + + + D+D + L + E K+ + Sbjct: 1192 RQERERQYREEEEL-------------QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238 Query: 145 A----RKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRRW 188 +E EQ + E ++ + S L +L G Q + + +RRW Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286 >gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] Length = 334 Score = 40.8 bits (94), Expect = 0.001 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 30/181 (16%) Query: 16 RGKGEGDLSQLSKQYS----SRDLP---SHTKIKYRQTTQDAPEEVRNRDFRRELEERER 68 RG+G+ Q S+ S SR P SH++ R + + R+R+ R+ ++ +R Sbjct: 88 RGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERRKGRDKEKR 147 Query: 69 AAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN-------------LDADDPL-TDEED 114 ++K +D+ S + K L+ +P A AD+ L E + Sbjct: 148 EKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKERN 207 Query: 115 EDFEEESDDDDTAALLAELEKIKKERAEE---------QARKEQEQKAEEERIRMENILS 165 E+ + ++D A L+ +++++K+ A E ++ KE ++ E ++ S Sbjct: 208 EEEAKRRKEEDQATLVEQVKRVKEIEAIESDSFVQQTFRSSKEVKKSVEPSEVKQATSTS 267 Query: 166 G 166 G Sbjct: 268 G 268 >gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 40.8 bits (94), Expect = 0.001 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 9/110 (8%) Query: 52 EEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTD 111 EE + +E + ER K R + + T VSK P D L D Sbjct: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE---------DKKKRLED 62 Query: 112 EEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 ++ + ++E D + AE E KKE E++ +E+E+K +EE+ + + Sbjct: 63 DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112 Score = 40.4 bits (93), Expect = 0.001 Identities = 43/187 (22%), Positives = 84/187 (44%), Gaps = 26/187 (13%) Query: 61 RELEERERAAAREKNRDR---PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDF 117 ++ ER +++E+ +D ++ + + KK RL+ D + DEE Sbjct: 23 KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA 82 Query: 118 EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKA------EEERIRM-------ENIL 164 EEES + E+ +K++ EEQA+++QE++A +EE I++ ++ Sbjct: 83 EEESKKKEEEEKKKHQEEERKKQ-EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLR 141 Query: 165 SGNPLLNLTGP-SQPQANF--KVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHK 221 N P S+P+ NF ++ + F K + +Q++ D+L +F+ Sbjct: 142 KELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR------DSLSHDFNG 195 Query: 222 KFMEKYI 228 + KYI Sbjct: 196 LNLSKYI 202 Score = 27.7 bits (60), Expect = 8.5 Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 104 DADDPLTDEE--DEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 D+ D +T+ E +ED EEE +T ++ + EE + + ++ EEE + Sbjct: 1018 DSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTD 1077 Query: 162 NILSGN 167 + N Sbjct: 1078 YLTDSN 1083 >gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 40.8 bits (94), Expect = 0.001 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 9/110 (8%) Query: 52 EEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTD 111 EE + +E + ER K R + + T VSK P D L D Sbjct: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE---------DKKKRLED 62 Query: 112 EEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 ++ + ++E D + AE E KKE E++ +E+E+K +EE+ + + Sbjct: 63 DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112 Score = 40.4 bits (93), Expect = 0.001 Identities = 43/187 (22%), Positives = 84/187 (44%), Gaps = 26/187 (13%) Query: 61 RELEERERAAAREKNRDR---PTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDF 117 ++ ER +++E+ +D ++ + + KK RL+ D + DEE Sbjct: 23 KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA 82 Query: 118 EEESDDDDTAALLAELEKIKKERAEEQARKEQEQKA------EEERIRM-------ENIL 164 EEES + E+ +K++ EEQA+++QE++A +EE I++ ++ Sbjct: 83 EEESKKKEEEEKKKHQEEERKKQ-EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLR 141 Query: 165 SGNPLLNLTGP-SQPQANF--KVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHK 221 N P S+P+ NF ++ + F K + +Q++ D+L +F+ Sbjct: 142 KELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR------DSLSHDFNG 195 Query: 222 KFMEKYI 228 + KYI Sbjct: 196 LNLSKYI 202 Score = 27.7 bits (60), Expect = 8.5 Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 104 DADDPLTDEE--DEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRME 161 D+ D +T+ E +ED EEE +T ++ + EE + + ++ EEE + Sbjct: 1018 DSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTD 1077 Query: 162 NILSGN 167 + N Sbjct: 1078 YLTDSN 1083 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 40.8 bits (94), Expect = 0.001 Identities = 30/165 (18%), Positives = 72/165 (43%), Gaps = 27/165 (16%) Query: 45 QTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLD 104 +++Q + EEV + ++ + E ++ E+ + E V + +++ + + Sbjct: 165 RSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE 224 Query: 105 ADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENIL 164 D+ +EE+E+ EEE ++++ +E EQ ++Q+++ + R E Sbjct: 225 VDEDGEEEEEEEEEEEEEEEE------------EEEEYEQDERDQKEEGNDYDTRSEASD 272 Query: 165 SGNPLLNLTGPSQPQANFKVKRRWDDDVVFKNCAKGVDDQKKDKR 209 SG+ ++ T D V + G D++KK+++ Sbjct: 273 SGSESVSFT---------------DGSVRSGSGTDGSDEKKKERK 302 Score = 36.6 bits (83), Expect = 0.018 Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 10/140 (7%) Query: 23 LSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAA------REKNR 76 LS + + ++ P T ++ R + A + R LE RA+ E N Sbjct: 117 LSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNS 176 Query: 77 DRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKI 136 + +H T SS S + + ++ + EEDE+ EE++++D+ E E+ Sbjct: 177 EEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV--EEDEEVEEDAEEDEEVDEDGEEEE- 233 Query: 137 KKERAEEQARKEQEQKAEEE 156 +E EE+ +E+E++ E+ Sbjct: 234 -EEEEEEEEEEEEEEEEYEQ 252 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.127 0.349 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,336,858 Number of Sequences: 37866 Number of extensions: 476465 Number of successful extensions: 11935 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 428 Number of HSP's successfully gapped in prelim test: 635 Number of HSP's that attempted gapping in prelim test: 5130 Number of HSP's gapped (non-prelim): 4048 length of query: 229 length of database: 18,247,518 effective HSP length: 99 effective length of query: 130 effective length of database: 14,498,784 effective search space: 1884841920 effective search space used: 1884841920 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.