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Search of human proteins with 116686122
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116686122 kinesin family member 4 [Homo sapiens]
(1232 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116686122 kinesin family member 4 [Homo sapiens] 2406 0.0
gi|150010604 kinesin family member 4B [Homo sapiens] 2264 0.0
gi|38569484 kinesin family member 21A [Homo sapiens] 472 e-133
gi|83716024 kinesin family member 21B [Homo sapiens] 426 e-119
gi|30794488 kinesin family member 27 [Homo sapiens] 382 e-106
gi|71061468 centromere protein E [Homo sapiens] 328 2e-89
gi|9910266 kinesin family member 15 [Homo sapiens] 315 1e-85
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 311 2e-84
gi|203096856 kinesin family member 7 [Homo sapiens] 308 2e-83
gi|46852174 kinesin family member 3A [Homo sapiens] 299 1e-80
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 299 1e-80
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 299 1e-80
gi|4758648 kinesin family member 5B [Homo sapiens] 290 6e-78
gi|4758650 kinesin family member 5C [Homo sapiens] 284 4e-76
gi|4758646 kinesin family member 3B [Homo sapiens] 283 5e-76
gi|45446749 kinesin family member 5A [Homo sapiens] 280 8e-75
gi|46852172 kinesin family member 13B [Homo sapiens] 279 1e-74
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 276 7e-74
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 276 7e-74
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 271 3e-72
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 271 3e-72
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 271 3e-72
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 271 3e-72
gi|13699824 kinesin family member 11 [Homo sapiens] 269 1e-71
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 269 1e-71
gi|41352705 kinesin family member 3C [Homo sapiens] 266 7e-71
gi|40254834 kinesin family member 1C [Homo sapiens] 261 3e-69
gi|7661878 kinesin family member 14 [Homo sapiens] 260 6e-69
gi|156616271 kinesin family member 19 [Homo sapiens] 258 2e-68
gi|148612831 kinesin family member 18A [Homo sapiens] 241 2e-63
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 2406 bits (6235), Expect = 0.0
Identities = 1232/1232 (100%), Positives = 1232/1232 (100%)
Query: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTE 60
MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTE
Sbjct: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTE 60
Query: 61 QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQ 120
QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQ
Sbjct: 61 QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQ 120
Query: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT
Sbjct: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
Query: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVD 240
VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVD
Sbjct: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVD 240
Query: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDS 300
LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDS
Sbjct: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDS 300
Query: 301 LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQ 360
LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQ
Sbjct: 301 LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQ 360
Query: 361 LQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERI 420
LQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERI
Sbjct: 361 LQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERI 420
Query: 421 ILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET 480
ILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET
Sbjct: 421 ILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET 480
Query: 481 VACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALA 540
VACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALA
Sbjct: 481 VACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALA 540
Query: 541 RKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRK 600
RKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRK
Sbjct: 541 RKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRK 600
Query: 601 RLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEK 660
RLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEK
Sbjct: 601 RLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEK 660
Query: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK 720
FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK
Sbjct: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK 720
Query: 721 QREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQ 780
QREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQ
Sbjct: 721 QREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQ 780
Query: 781 LKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK 840
LKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK
Sbjct: 781 LKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK 840
Query: 841 LLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQK 900
LLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQK
Sbjct: 841 LLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQK 900
Query: 901 MLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLL 960
MLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLL
Sbjct: 901 MLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLL 960
Query: 961 STLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEY 1020
STLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEY
Sbjct: 961 STLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEY 1020
Query: 1021 VPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEWKPTKLVKVSR 1080
VPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEWKPTKLVKVSR
Sbjct: 1021 VPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEWKPTKLVKVSR 1080
Query: 1081 KNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEGSF 1140
KNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEGSF
Sbjct: 1081 KNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEGSF 1140
Query: 1141 KLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEY 1200
KLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEY
Sbjct: 1141 KLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEY 1200
Query: 1201 QENKAPGKKKKRALASNTSFFSGCSPIEEEAH 1232
QENKAPGKKKKRALASNTSFFSGCSPIEEEAH
Sbjct: 1201 QENKAPGKKKKRALASNTSFFSGCSPIEEEAH 1232
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 2264 bits (5866), Expect = 0.0
Identities = 1157/1234 (93%), Positives = 1187/1234 (96%), Gaps = 2/1234 (0%)
Query: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTE 60
MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGE QVVVGTDKSFTYDFVFDP TE
Sbjct: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTE 60
Query: 61 QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQ 120
QEEVFN AVAPLIKG+FKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVG+IPRVIQ
Sbjct: 61 QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQ 120
Query: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT
Sbjct: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
Query: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVD 240
VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTIS+EQRKKSDKN SFRSKLHLVD
Sbjct: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVD 240
Query: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDS 300
LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKG FVPYRDSKLTRLLQDS
Sbjct: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDS 300
Query: 301 LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQ 360
LGGNSHTLMIACVSPADSNLEETL+TLRYADRARKIKNKPIVNIDP TAELNHLKQQVQQ
Sbjct: 301 LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQ 360
Query: 361 LQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERI 420
LQVLLLQAHGGTLPGSI EPSENLQSLMEKNQSLVEENEKLSR LS+AAGQTAQMLERI
Sbjct: 361 LQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERI 420
Query: 421 ILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET 480
ILTEQ NEK+NAKLEELRQH ACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET
Sbjct: 421 ILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET 480
Query: 481 VACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALA 540
VAC AAAIDTAVE+EAQVETSPETSRSSDAFTTQHAL QAQMSKE+VELN ALALKEAL
Sbjct: 481 VACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALV 540
Query: 541 RKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRK 600
RKMTQND+QLQPIQ+QYQDNIK LELEVINLQKEKEELV ELQTAKK+ NQAKLSE R K
Sbjct: 541 RKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHK 600
Query: 601 RLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEK 660
LQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEI MMKNQRVQLMRQMKEDAEK
Sbjct: 601 LLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEK 660
Query: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK 720
FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQS+VLRRKTEEAAAANKRLKDALQK
Sbjct: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQK 720
Query: 721 QREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQ 780
QREV DKRKETQS G EG AARV+NWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDV Q
Sbjct: 721 QREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQ 780
Query: 781 LKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK 840
LKEKKES ENPPPKLR+ TFSL+EV GQV ESED ITKQIESLETEME RSAQIADLQQK
Sbjct: 781 LKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQK 840
Query: 841 LLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQK 900
LLDAESEDRPKQ WENIATILEAKCALKYLIGELVSSKI V+KLE+SL+QSK SCADMQK
Sbjct: 841 LLDAESEDRPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQK 900
Query: 901 MLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLL 960
MLFEE+NHF+EIETELQAELVRMEQQHQEKVLYL+SQLQ+SQMAEKQLE+S SEKEQQL+
Sbjct: 901 MLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLV 960
Query: 961 STLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEY 1020
STL+CQDEELEKMREVCEQNQQLL+ENEIIKQKL LLQVASRQKHLP DTLLSPDSSFEY
Sbjct: 961 STLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEY 1020
Query: 1021 VPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHE--DGDGDDDEGDDEEWKPTKLVKV 1078
+PPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHE DGDGD DEGDDEEWKPTKLVKV
Sbjct: 1021 IPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEWKPTKLVKV 1080
Query: 1079 SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEG 1138
SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDC CDPTKCRNRQQGKDSLGTVE+TQDSEG
Sbjct: 1081 SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCSCDPTKCRNRQQGKDSLGTVEQTQDSEG 1140
Query: 1139 SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVAT 1198
SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCD+EQVLSKKT PAPSPFDLPE KH AT
Sbjct: 1141 SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDMEQVLSKKTAPAPSPFDLPESKHGAT 1200
Query: 1199 EYQENKAPGKKKKRALASNTSFFSGCSPIEEEAH 1232
EYQ+NK PGKKKKRALASNTSFFSGCSPIEEEAH
Sbjct: 1201 EYQQNKPPGKKKKRALASNTSFFSGCSPIEEEAH 1234
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 472 bits (1215), Expect = e-133
Identities = 336/1083 (31%), Positives = 541/1083 (49%), Gaps = 176/1083 (16%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAV 69
VRVA+R RP + KE EGC +C S PGEPQV +G DK+FT+D+VFD ++QE+++ +
Sbjct: 10 VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCI 69
Query: 70 APLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKK 129
LI+G F+GYNATV AYGQTG+GKTY+MG + E +G+I R ++ LFK I++K
Sbjct: 70 EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEE-ELGIISRAVKHLFKSIEEK 128
Query: 130 SDF---------EFTLKVSYLEIYNEEILDLLCPSRE------KAQINIREDPKEGIKIV 174
+F + +LE+YNEE+LDL +R+ K+ I I ED GI V
Sbjct: 129 KHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTV 188
Query: 175 GLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK---------- 224
G+T +TV + + CL+ G SRT AST MN QSSRSHAIFTI + Q +
Sbjct: 189 GVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADNA 248
Query: 225 ----------KSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVI 274
+ ++ + +K H VDLAGSER K+T A G+R KEGI+IN GLL LGNVI
Sbjct: 249 TDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVI 308
Query: 275 SALGD-DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRA 333
SALGD K+ VPYRDSKLTRLLQDSLGGNS T+MIACVSP+D + ETLNTL+YA+RA
Sbjct: 309 SALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRA 368
Query: 334 RKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQ 393
R IKNK +VN D + ++N L+ ++ +LQ+ L++ G I E E++ + +N
Sbjct: 369 RNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTG--KRIIDEEGVESINDMFHENA 426
Query: 394 SLVEENEKLSRGLSEAAGQTAQMLERI--ILTEQAN--------------EKMNAKLEEL 437
L EN L + + RI ++++QAN +++ ++E+
Sbjct: 427 MLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEI 486
Query: 438 RQHAACKLDLQKLVETLED-----------------------QELKENVEIICNLQQLIT 474
A L+ + + E L KE +EII ++ +
Sbjct: 487 EDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLE 546
Query: 475 QL------SDETVACMAAAIDTAVEQ------------EAQVETSPETS----------- 505
+L ++VA DT E+ E +VE S E S
Sbjct: 547 KLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEE 606
Query: 506 --------RSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQY 557
SSD + + +A +L + +A+K+ L ++ + +LQ ++ QY
Sbjct: 607 EEDDIDGGESSDE-SDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQY 665
Query: 558 QDNIKELELEVINLQKEKEELVLELQTAK--KDANQAKLSERRRKRLQELEGQIADLKKK 615
++ + L+ ++ + Q E+++++ L + + + K+ K+LQ + ++ L+
Sbjct: 666 EEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAA 725
Query: 616 LNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQL 675
E ++LLK + E+ + KL Q++ MK +V+LM+QMKE+ EK R + ++++E+ QL
Sbjct: 726 QKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQL 785
Query: 676 KERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK-----QREVADKRKE 730
K+ RKR ++L LE + Q VLRRKTEE A ++++ K R+++
Sbjct: 786 KKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAP 845
Query: 731 TQSRGMEGTAARV---KNWLGNEIEVMVSTEEA--------------------------- 760
Q G A + ++ + V+ +A
Sbjct: 846 AQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKT 905
Query: 761 --------KRHLNDLLEDRKILAQ---DVAQLKEKKESGENPPPKLRRRTFSLTEVRGQV 809
+R + D++ + ++ D+ +L +++E KL +R + + G+
Sbjct: 906 ARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEG 965
Query: 810 SESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWE-----NIATILEAK 864
++ +I +++ESL +++ + I+D Q ++ E + + N T+ EA+
Sbjct: 966 DKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEAR 1025
Query: 865 CALKYLIG-------ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQ 917
L + + + + Q+ LE LKQ++ + A ++LF AE+ EL
Sbjct: 1026 YLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELD 1085
Query: 918 AEL 920
A L
Sbjct: 1086 ALL 1088
Score = 51.6 bits (122), Expect = 5e-06
Identities = 80/414 (19%), Positives = 171/414 (41%), Gaps = 33/414 (7%)
Query: 596 ERRRKRLQELEGQIADLKKKLNEQSKLLKL-KESTERTVSKLNQEIRMMKNQRVQL---M 651
+R +++ L +I L+ +L E ++ E +++ + E M++ + L +
Sbjct: 380 DRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRI 439
Query: 652 RQMKEDAEKFR-QWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAA 710
+ M+E + R + Q + + R + E+ + ++ K+ LR K E+ A
Sbjct: 440 KAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAV 499
Query: 711 NKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLED 770
N+ L+ L R ++ G++ L ++ E + + AK+ L L
Sbjct: 500 NENLRKNLT--------RATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRK 551
Query: 771 RKILAQDVAQLKEK----KESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETE 826
K + VA ++ +E E R E +VS+ ED ++ E E E
Sbjct: 552 EKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHED---EEEEEEEEE 608
Query: 827 MEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKY-LIGELVSSKIQVSKL- 884
+ + +D +++SE K ++ + + A+K LI EL +S+ ++ L
Sbjct: 609 DDIDGGESSD------ESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLK 662
Query: 885 ---ESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQS 941
E L + D Q + + +E+ + + ++ ++++K+ + +LQ+
Sbjct: 663 KQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRL 722
Query: 942 QMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLT 995
Q A+K+ + + Q K Q + +E + +Q+ E E K +LT
Sbjct: 723 QAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQE--KARLT 774
Score = 34.7 bits (78), Expect = 0.58
Identities = 49/276 (17%), Positives = 122/276 (44%), Gaps = 35/276 (12%)
Query: 805 VRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAK 864
++ +V ++D ++QI +L +E I LQ +L++ ++ R E + +I +
Sbjct: 371 IKNKVMVNQDRASQQINALRSE-------ITRLQMELMEYKTGKRIIDE-EGVESINDMF 422
Query: 865 CALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRME 924
L E + ++++ ++ ++ ++ + +++ ++ NH E E+ M
Sbjct: 423 HENAMLQTENNNLRVRIKAMQETVDALRSR---ITQLVSDQANHVLARAGEGNEEISNMI 479
Query: 925 QQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQ---------LLSTLKCQDEELEKMRE 975
+ +++ L ++L +S+ + L ++++ + T+ D+E ++ +
Sbjct: 480 HSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIID 539
Query: 976 VCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKF- 1034
+ +++ + L+ E K+K VA ++ + D+ E K R +
Sbjct: 540 LAKKDLEKLKRKEKRKKK----SVAGKEDNT--------DTDQEKKEEKGVSERENNELE 587
Query: 1035 LEQSMDIEDLKYCSEHSVNEHEDGDGDD--DEGDDE 1068
+E+S ++ D + E E +D DG + DE D E
Sbjct: 588 VEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE 623
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 426 bits (1095), Expect = e-119
Identities = 339/1129 (30%), Positives = 548/1129 (48%), Gaps = 195/1129 (17%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAV 69
V+VA+R RP + KE EGC +C S PGEPQV++G DK+FTYDFVFD T QE++++T V
Sbjct: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCV 68
Query: 70 APLIKGVFKGYNATVLAYGQTGSGKTYSMGGAY---TAEQENEPTVGVIPRVIQLLFKEI 126
+ LI+G F+GYNATVLAYGQTG+GKTY+MG + T+E+E G+IPR I LF I
Sbjct: 69 SKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQ----GIIPRAIAHLFGGI 124
Query: 127 DKK---------SDFEFTLKVSYLEIYNEEILDLLCPSRE------KAQINIREDPKEGI 171
++ + EF + +LE+YNEEILDL +R+ ++ I I ED GI
Sbjct: 125 AERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGI 184
Query: 172 KIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK------- 224
G+T + + + + CL+QG SRT AST MN QSSRSHAIFTI L Q +
Sbjct: 185 YTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDL 244
Query: 225 -------------KSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLG 271
S + + +K H VDLAGSER K+T A G+R KEGI+IN GLL LG
Sbjct: 245 VNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 304
Query: 272 NVISALGD-DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYA 330
NVISALGD KK VPYRDSKLTRLLQDSLGGNS T+MIACVSP+D + ETLNTL+YA
Sbjct: 305 NVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYA 364
Query: 331 DRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLME 390
+RAR IKNK +VN D + +++ L+ ++ +LQ+ L++ G I + +E L
Sbjct: 365 NRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAG--KRVIGEDGAEGYSDLFR 422
Query: 391 KNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQ-HAACKLDLQK 449
+N L +EN L L A Q A +T+ +++ N L + + A +Q
Sbjct: 423 ENAMLQKENGALR--LRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQN 480
Query: 450 LVETLED--QELKENVEIICNLQQLITQLSDE---TVACMAAAIDTAVEQEAQVETSPET 504
+ +E+ +L E+ + +L++ +++ S ++ AA + +E + E
Sbjct: 481 YIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEV 540
Query: 505 SRSSD---AFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQP--------- 552
R + + +RQ + S E K L++ + + +N+++ +
Sbjct: 541 IRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCE 600
Query: 553 -------------IQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRR 599
+ D+ + E + +N Q + +L E++ +K ++ + S+RR
Sbjct: 601 EEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRL 660
Query: 600 KRLQE--------LEGQI-----------------------------ADLKKKL------ 616
+ L+ L+ +I AD +K+L
Sbjct: 661 QTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRD 720
Query: 617 --------NEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKK 668
E ++LLK + ER + KL E+ MK +V LM+QM+E+ ++ R + K+
Sbjct: 721 LQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKR 780
Query: 669 DKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKR 728
++E+ QLK+ R++++++ LE ++Q VLRRKT+E +A + K ++ A +
Sbjct: 781 NREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLK 840
Query: 729 KETQSRGMEGTAA----------------------RVKNWLGNEIEVMVS---------- 756
G E +A+ ++ ++LG+ V+
Sbjct: 841 PPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQ 900
Query: 757 ---------------TEEAKRHLNDLLEDRKI---LAQDVAQLKEKKESGENPPPKLRRR 798
+ +R + D++ R L D+ +L +K+E LRR+
Sbjct: 901 KKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRK 960
Query: 799 TFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWE--- 855
L + + + ++IE L +++ + I D Q ++ E +
Sbjct: 961 RERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSV 1020
Query: 856 --NIATILEAKCALKYLIGELVSSKIQVSK-------LESSLKQSKTSCADMQKMLFEER 906
+ ++ EA+ L + + +QV++ LE L+Q+ + + +L +
Sbjct: 1021 VISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDAL 1080
Query: 907 NHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEK 955
AE ELQA + ++Q++ Y + + S+ +E +S + K
Sbjct: 1081 REKAEAHPELQALIYNVQQENG----YASTDEEISEFSEGSFSQSFTMK 1125
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 382 bits (982), Expect = e-106
Identities = 320/1092 (29%), Positives = 521/1092 (47%), Gaps = 152/1092 (13%)
Query: 8 IPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNT 67
IPV+VA+R RPL+ KE Q+C+ +P QV++G D+ FT+DFVF ++ Q+EV+NT
Sbjct: 4 IPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYNT 63
Query: 68 AVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEID 127
+ PL+ + +GYNATV AYGQTGSGKTY++GG + A E G+IPR IQ +F+ I
Sbjct: 64 CIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVV-EGQKGIIPRAIQEIFQSIS 122
Query: 128 KKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDT 187
+ +F +KVSY+E+Y E++ DLL ++IRED K IVG E V A +
Sbjct: 123 EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAGEV 182
Query: 188 VSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSS---------FRSKLHL 238
+S LE GN +R +T MN SSRSHAIFTIS+ Q K+ + + SK H
Sbjct: 183 MSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFHF 242
Query: 239 VDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDD-KKGGFVPYRDSKLTRLL 297
VDLAGSER KT G+R KE I IN GLL LGNVISALGD +K +PYRD+K+TRLL
Sbjct: 243 VDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRLL 302
Query: 298 QDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQ 357
+DSLGG++ T+MI CVSP+ SN +E+LN+L+YA+RAR I+NKP VN P++ ++ ++ +
Sbjct: 303 KDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFE 362
Query: 358 VQQL-QVLLLQAHGGTLPGSITVEPS---ENLQSLMEK----------NQSLVEE----- 398
++ L + L Q G + I E S + SL E+ Q VEE
Sbjct: 363 IKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFL 422
Query: 399 ---------NEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAA------- 442
NEK L E Q + + +LT A LEE QH
Sbjct: 423 VDLKDTVRLNEKQQHKLQEWFNM-IQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRE 481
Query: 443 -----CKLDLQKLV---ETLEDQELKENVEI-------------------------ICNL 469
C L ++V + LE +ELK V++ I
Sbjct: 482 LKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQ 541
Query: 470 QQLITQLSDETVACMAAAIDTAVEQ--EAQVETSPETSRSSDAFTT----------QHAL 517
Q L+ QLS+E + +A E + PE + F T +
Sbjct: 542 QLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDS 601
Query: 518 RQAQMSKELVELNKALALKEALARKMTQN-DSQLQPIQYQYQDNIKELE----------- 565
R+ S + L++ A ++ + + + Q + + Q+ DN + E
Sbjct: 602 RKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRC 661
Query: 566 ---------------LEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIA 610
+E+ + Q E ++ LE + K D Q + E ++L+ E +
Sbjct: 662 RSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQ-ESQELNLQKLKNSERILT 720
Query: 611 DLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDK 670
+ K+K+ E + +K+KE + + K + + + Q + +++ DAE+ + + K
Sbjct: 721 EAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQK 780
Query: 671 EVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKE 730
++ +L+ +D +KL++ F+K+ + + + + K+ +D+ K+ + E
Sbjct: 781 QLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQ---VLQKKQQDS--KKLASLSIQNE 835
Query: 731 TQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGEN 790
++ +E + +K + +++ + E KR D + R QLK +E G
Sbjct: 836 KRANELEQSVDHMK-YQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLK 894
Query: 791 PPPK------LRRRTFS---------LTEVRGQVSESEDSITKQ---IESLETEMEFRSA 832
P + L+RR S L E + + E + + Q +E LE +++ R A
Sbjct: 895 PKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREA 954
Query: 833 QIADLQQKLLDAESEDRPKQRWENIATI--LEAKCALKYLIGELVSSKIQVSKLESSLKQ 890
++ + L + + K R L+ L L EL +Q L++S +
Sbjct: 955 IVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQ---LQTSTAE 1011
Query: 891 SKTSCADMQKMLFEERNHFAEIETELQAELV--RMEQQHQEKVLYLLSQ-LQQSQMAEKQ 947
KT ++ ++L +E++ + + +L R+ +E VL+ L + ++ + A +
Sbjct: 1012 EKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEY 1071
Query: 948 LEESVSEKEQQL 959
ES+ +++ L
Sbjct: 1072 RNESIQNRQKSL 1083
Score = 92.8 bits (229), Expect = 2e-18
Identities = 119/572 (20%), Positives = 250/572 (43%), Gaps = 78/572 (13%)
Query: 466 ICNLQQLITQLSDETVACMAAAIDTAVE--QEAQVETSPETSRSSDAFTTQHALRQAQMS 523
+C+L +L + DET D ++ QE+Q E + + ++S+ T+
Sbjct: 673 VCSLVEL-SDTQDETQKSDLENEDLKIDCLQESQ-ELNLQKLKNSERILTE-------AK 723
Query: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELE-------LEVINLQKEKE 576
+++ EL + +KE L +++ + + + + QY + +LE +E+I QK+ +
Sbjct: 724 QKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQ 783
Query: 577 ELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKL 636
EL E + A + KL + RK++ + ++ L+KK + KL L E+ ++L
Sbjct: 784 EL--ENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANEL 841
Query: 637 NQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKR-QYELLKLERNFQK 695
Q + MK Q++QL R+++E+ EK +Q ++ ++KE K Q E LK +
Sbjct: 842 EQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLD 901
Query: 696 QSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMV 755
N+ RRK + + + D +K + ++ Q + +E A +K + E +V
Sbjct: 902 ACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLK-----KREAIV 956
Query: 756 STEEAKRHLNDLLEDRKI----------------------------------LAQDVAQL 781
S +EA LE++K+ A++ ++
Sbjct: 957 SKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKI 1016
Query: 782 KEKKESGENPPPKLRRRTFSLTE--VRGQVSESED-----SITKQIESLETEMEFRSAQI 834
E+ E + +L++R ++ E G+V E+ + + IE+LE +E+R+ I
Sbjct: 1017 SEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESI 1076
Query: 835 ADLQQKLLDAESEDRPKQR---WENIATI--LEAKCALKYLIGELVSSKIQVSKLESSLK 889
+ +QK L A + + E +A + +E + L ++V+ + K + +
Sbjct: 1077 QN-RQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNE 1135
Query: 890 QSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQS-----QMA 944
+ K + M+ E + ++ + L +++H++K+ LL ++
Sbjct: 1136 EMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMET 1195
Query: 945 EKQLEESVSEKEQQLLSTLKCQDEELEKMREV 976
K E+ + + E+ L K + +K++E+
Sbjct: 1196 FKTYEDKIQQLEKDLYFYKKTSRDHKKKLKEL 1227
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 328 bits (841), Expect = 2e-89
Identities = 302/1071 (28%), Positives = 500/1071 (46%), Gaps = 146/1071 (13%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTD--KSFTYDFVFDPSTEQEEVFNT 67
V V +R RPL +E S G + + + V+ D KSF +D VF + + V+
Sbjct: 7 VAVCVRVRPLNSREESLG-ETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVYEE 65
Query: 68 AVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEID 127
AP+I +GYN T+ AYGQT SGKTY+M G+ E +GVIPR I +F++I
Sbjct: 66 IAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGS-------EDHLGVIPRAIHDIFQKIK 118
Query: 128 KKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDT 187
K D EF L+VSY+EIYNE I DLLC +++ + IRED + + LTE+ V +
Sbjct: 119 KFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMA 178
Query: 188 VSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSD----KNSSFRSKLHLVDLAG 243
+ + +G SR T MN +SSRSH IF + LE R+K + + S S L+LVDLAG
Sbjct: 179 LKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNLVDLAG 238
Query: 244 SERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGG 303
SER +T A G RLKEG NINR L LG VI L D + GGF+ YRDSKLTR+LQ+SLGG
Sbjct: 239 SERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGG 298
Query: 304 NSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVN-IDPQTAELNHLKQQVQQLQ 362
N+ T +I ++P + +ETL L++A A+ +KN P VN + A L ++++ L+
Sbjct: 299 NAKTRIICTITPV--SFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLK 356
Query: 363 VLLLQAHGGTLPGSITVEPSENLQSLMEKNQ--SLVEENEKLSRGLSEAAGQTAQMLERI 420
L + E MEK+Q L+EE + L + +E +ML
Sbjct: 357 KQLEEV------------SLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRML--- 401
Query: 421 ILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQL---S 477
+ + + K + R+ C + K+ + + I +L L
Sbjct: 402 VTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREI 461
Query: 478 DETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKE 537
DE+V + ++ +++E +P T +++E +E
Sbjct: 462 DESVCSESDVFSNTLDTLSEIEWNPATK---------------LLNQENIE--------- 497
Query: 538 ALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSER 597
S+L ++ Y + L L+ L+ EKEE+ L+L+ K D ++ + ER
Sbjct: 498 ----------SELNSLRADYDN----LVLDYEQLRTEKEEMELKLK-EKNDLDEFEALER 542
Query: 598 RRKRLQELE--GQIADLKKKL-----------NEQSKLLKLKESTERTVSKLNQEIRMMK 644
+ K+ QE++ +I++LK + NE S ++L E + KL + I K
Sbjct: 543 KTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQK 602
Query: 645 NQRVQL-MRQMKEDAEKFRQWKQKK-DKEVIQLKERDRKRQYELLKLERNFQKQSNVLRR 702
+ +++ + E E +Q KQ D E + L D KR+ L+ E N + L+
Sbjct: 603 LENIKMDLSYSLESIEDPKQMKQTLFDAETVAL---DAKRESAFLRSE-NLE-----LKE 653
Query: 703 KTEEAAAANKRLKDALQ--------KQREVADKRKETQSRGMEGTA------ARVKNWLG 748
K +E A K++++ +Q K++ D KE QS E T +V L
Sbjct: 654 KMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLL 713
Query: 749 NEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQ 808
+E+ + ++ LN +E+ + L ++V L E K S + +LR+ +E
Sbjct: 714 CNLELEGKITDLQKELNKEVEENEALREEVILLSELK-SLPSEVERLRKEIQDKSEELHI 772
Query: 809 VSESEDSITKQIESLETEMEFRSAQIA----DLQQKLLDAESEDRPKQRWENIATILEAK 864
++ +D + ++ E+ ++ +I DL + +S D+ Q ++ + E K
Sbjct: 773 ITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQK 832
Query: 865 CAL-----KYLIGELVSSKIQVSKLESSLKQSKTSCA-------DMQKMLFEERNHFAEI 912
+ + + E+V+ + K +SSL KT + + + + E N ++
Sbjct: 833 YKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL 892
Query: 913 ETELQAELVRMEQQHQEKVLYL---------LSQLQQSQMAEKQLEESVSEKEQQLLS-- 961
+ +L+ ++ +EK L + L Q + KQL+ES+ + QL S
Sbjct: 893 KEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDI 952
Query: 962 --TLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDT 1010
T+ + E++R E +Q +K K++ + SR H+ ++T
Sbjct: 953 HDTVNMNIDTQEQLRNALESLKQHQETINTLKSKIS--EEVSRNLHMEENT 1001
Score = 89.7 bits (221), Expect = 2e-17
Identities = 182/896 (20%), Positives = 366/896 (40%), Gaps = 117/896 (13%)
Query: 120 QLLFKEIDKKSDFEFTLKVSY-LEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTE 178
Q+L I +K + LK + + I N+E L LL +K Q + ++ IK G
Sbjct: 1057 QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1116
Query: 179 KTVLVALDTVSCL-EQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLH 237
+T + L E+ + +N Q S E +KK ++ + +++L
Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMS--------EMQKKINEIENLKNELK 1168
Query: 238 LVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLL 297
+L + + +L E + + V+ L + F RD +
Sbjct: 1169 NKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKEL----QKSFETERDHLRGYIR 1224
Query: 298 QDSLGG--NSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLK 355
+ G L IA + + +ET++ LR R + K I+ Q E +H K
Sbjct: 1225 EIEATGLQTKEELKIAHIHLKEH--QETIDELR-----RSVSEKTAQIINTQDLEKSHTK 1277
Query: 356 QQVQQLQVLLLQAHGGTLPG----SITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAG 411
Q + + +L LP S T E L+ L E QS +++ L+R
Sbjct: 1278 LQEE---IPVLHEEQELLPNVKEVSETQETMNELELLTE--QSTTKDSTTLAR------- 1325
Query: 412 QTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLE--DQELKENV-EIICN 468
+ER+ L NEK EE++ + +L+ + E LE +LKE++ E +
Sbjct: 1326 ---IEMERLRL----NEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAK 1378
Query: 469 LQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVE 528
+Q+ +Q E M +E ET+ S AL + ++ E++
Sbjct: 1379 IQE--SQSKQEQSLNM---------KEKDNETTKIVSEMEQFKPKDSALLRIEI--EMLG 1425
Query: 529 LNKALALKEALARKMTQNDSQLQPIQYQYQ---DNIKELELEVINLQKEKEELVLELQTA 585
L+K L + + + LQ +Q Q D +KE E++ E EE +
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCC 1485
Query: 586 KKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKN 645
K+ Q + R L E E +I+ ++K+L + + + + ++ ++
Sbjct: 1486 LKE--QEETINELRVNLSEKETEISTIQKQLEA------INDKLQNKIQEIYEKEEQFNI 1537
Query: 646 QRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTE 705
+++ +++ + ++F++ ++ KD + ++ + EL + Q++ ++ ++ E
Sbjct: 1538 KQISEVQEKVNELKQFKEHRKAKDSALQSIESK----MLELTNRLQESQEEIQIMIKEKE 1593
Query: 706 EAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLN 765
E KR+++ALQ +R D+ KE A++K E + + T +N
Sbjct: 1594 EM----KRVQEALQIER---DQLKENTKE----IVAKMKESQEKEYQFLKMTA-----VN 1637
Query: 766 DLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLET 825
+ E ++ LKE+ E+ + + LT++ + E S+TK+ + L +
Sbjct: 1638 ETQEKMC----EIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRS 1693
Query: 826 EMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLE 885
E + L++ L + + D KQ LK + L + + KL
Sbjct: 1694 VEETLKVERDQLKENLRETITRDLEKQE------------ELKIVHMHLKEHQETIDKLR 1741
Query: 886 SSLKQSKTSCADMQKMLFEERNHFAEIETELQAEL------VRMEQQHQEKVLYLLSQ-L 938
+ + ++MQK L + + ++Q EL ++ +Q+ +K+ ++S+
Sbjct: 1742 GIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKT 1801
Query: 939 QQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKL 994
+ +K LE S + K Q+ + LK + +L +++ + Q+ + E E +K+++
Sbjct: 1802 DKLSNMQKDLENS-NAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQI 1856
Score = 89.0 bits (219), Expect = 3e-17
Identities = 207/900 (23%), Positives = 382/900 (42%), Gaps = 129/900 (14%)
Query: 215 IFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVI 274
I + E K+ ++N + R ++ L+ K +E +RL++ I L ++I
Sbjct: 722 ITDLQKELNKEVEENEALREEVILLS-----ELKSLPSEVERLRKEIQDKSEEL---HII 773
Query: 275 SALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLE-ETLNTLRYADRA 333
++ DK V +++S++ LL++ +G L + ++ E + TL + D
Sbjct: 774 TS-EKDKLFSEVVHKESRVQGLLEE-IGKTKDDLATTQSNYKSTDQEFQNFKTL-HMDFE 830
Query: 334 RKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQ 393
+K K N + E+ +L ++ Q+ L G++ E S Q L EK +
Sbjct: 831 QKYKMVLEEN-ERMNQEIVNLSKEAQKFDSSL---------GALKTELSYKTQELQEKTR 880
Query: 394 SLVE---ENEKLSRGLSEAAGQTAQMLER--IILTEQANEKMNAKLEELRQHAACKLDLQ 448
+ E E E+L L E T Q +ER ++TE K+ LEE++ K DL+
Sbjct: 881 EVQERLNEMEQLKEQL-ENRDSTLQTVEREKTLITE----KLQQTLEEVKTLTQEKDDLK 935
Query: 449 KLVETL--EDQELKENVEIICNL-----QQLITQLSD-----ETVACMAAAIDTAVEQEA 496
+L E+L E +LK ++ N+ +QL L ET+ + + I V +
Sbjct: 936 QLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNL 995
Query: 497 QVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQ 556
+E + T + D F +++V ++K K+ L K TQ +
Sbjct: 996 HMEEN--TGETKDEF-----------QQKMVGIDK----KQDLEAKNTQT------LTAD 1032
Query: 557 YQDN-IKELELEVINLQKEKEEL--VLELQTAKKDANQAKLSERRRKRLQ---ELEGQIA 610
+DN I E + ++ +L +EK EL +LE A+K+ + L E ++ EL
Sbjct: 1033 VKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGD 1092
Query: 611 DLKKK----LNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKE--DAEKFRQW 664
+LKK+ E++ +K + RT +L + +K + QL + ++ + ++
Sbjct: 1093 ELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSE 1152
Query: 665 KQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLK--DALQKQR 722
QKK E+ LK + ++ L +E + + L EE + K K LQK
Sbjct: 1153 MQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSF 1212
Query: 723 EVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQ-- 780
E R +E T + K E+ ++ K H + E R+ +++ AQ
Sbjct: 1213 ETERDHLRGYIREIEATGLQTKE------ELKIAHIHLKEHQETIDELRRSVSEKTAQII 1266
Query: 781 ----LKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIAD 836
L++ + P L L V+ +VSE+++++ + E S +A
Sbjct: 1267 NTQDLEKSHTKLQEEIPVLHEEQELLPNVK-EVSETQETMNELELLTEQSTTKDSTTLAR 1325
Query: 837 LQQKLLD-----AESEDRPK---QRWENIATILEA----KCALKYLIGELVSSKIQ--VS 882
++ + L ES++ K + +N+ TI EA LK I E + +KIQ S
Sbjct: 1326 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETL-AKIQESQS 1384
Query: 883 KLESSL----KQSKTSCADMQKMLFEERNH-FAEIETELQAELVRMEQQHQE-----KVL 932
K E SL K ++T+ + F+ ++ IE E+ R+++ H E K
Sbjct: 1385 KQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEK 1444
Query: 933 YLLSQLQQSQMAEK-QLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEI-I 990
L +LQ+ +E QL+E++ E + L T +EEL+ ++ ++ + E + +
Sbjct: 1445 DDLQRLQEVLQSESDQLKENIKEIVAKHLET----EEELKVAHCCLKEQEETINELRVNL 1500
Query: 991 KQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQSMDIEDLKYCSEH 1050
+K T + +Q D L + + + K + +K+ E + +LK EH
Sbjct: 1501 SEKETEISTIQKQLEAINDKL---QNKIQEIYEKEEQFNIKQ-ISEVQEKVNELKQFKEH 1556
Score = 85.9 bits (211), Expect = 2e-16
Identities = 161/749 (21%), Positives = 318/749 (42%), Gaps = 89/749 (11%)
Query: 318 SNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSI 377
SN +TL+ + + + A K+ N+ NI+ +ELN L+ L + Q +
Sbjct: 473 SNTLDTLSEIEW-NPATKLLNQE--NIE---SELNSLRADYDNLVLDYEQ---------L 517
Query: 378 TVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERI-----------ILTEQA 426
E E L EKN ++E E L R + Q Q++ I + +
Sbjct: 518 RTEKEEMELKLKEKND--LDEFEALERKTKK--DQEMQLIHEISNLKNLVKHAEVYNQDL 573
Query: 427 NEKMNAKLEELRQHAACKLDLQKLVETLEDQELKE-------NVEIICNLQQLITQLSDE 479
++++K+E LR+ ++KL E ++ Q+L+ ++E I + +Q+ L D
Sbjct: 574 ENELSSKVELLREKED---QIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDA 630
Query: 480 TVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQH---ALRQAQMS---KELVELNKAL 533
+ A ++A + +E + + + L Q+Q+ K V+L K L
Sbjct: 631 ETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKEL 690
Query: 534 ALKEALARKMTQNDSQLQPIQYQYQDNIKELELE--VINLQKEKEELVLELQTAKKDANQ 591
K+T P +D + LELE + +LQKE + V E + +++
Sbjct: 691 QSAFNEITKLTSLIDGKVP-----KDLLCNLELEGKITDLQKELNKEVEENEALREEVIL 745
Query: 592 AKLSERRRKRLQELEGQIADLKKKLN----EQSKLLKLKESTERTVSKLNQEIRMMKNQR 647
+ ++ L +I D ++L+ E+ KL E V L +EI K+
Sbjct: 746 LSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDL 805
Query: 648 VQLMRQMKEDAEKFRQWKQK----KDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRK 703
K ++F+ +K + K + L+E +R Q E++ L + QK + L
Sbjct: 806 ATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQ-EIVNLSKEAQKFDSSLGAL 864
Query: 704 TEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAK-- 761
E + + L++ K REV ++ E + ++K L N + + E K
Sbjct: 865 KTELSYKTQELQE---KTREVQERLNEME---------QLKEQLENRDSTLQTVEREKTL 912
Query: 762 --RHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLT----EVRGQVSESEDS 815
L LE+ K L Q+ LK+ +ES + +L+ + + Q+ + +S
Sbjct: 913 ITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALES 972
Query: 816 ITKQIESLETEMEFRSAQIA-DLQQKLLDAESEDRPKQRWENI--ATILEAKCALKYLIG 872
+ + E++ T S +++ +L + E++D +Q+ I LEAK
Sbjct: 973 LKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTAD 1032
Query: 873 ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVL 932
+ I+ + SL Q K M + + E+ +++T+L+ E + M ++QE++
Sbjct: 1033 VKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKE---QLKTDLK-ENIEMTIENQEELR 1088
Query: 933 YLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQ 992
L +L++ Q Q + +KE +L T E EK++E +Q Q+ ++ +++
Sbjct: 1089 LLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQE 1148
Query: 993 KLTLLQVASRQKHLPKDTLLSPDSSFEYV 1021
+++ +Q + K+ L + + + E++
Sbjct: 1149 EMSEMQKKINEIENLKNELKNKELTLEHM 1177
Score = 71.6 bits (174), Expect = 4e-12
Identities = 189/972 (19%), Positives = 391/972 (40%), Gaps = 190/972 (19%)
Query: 159 AQINIREDPKEGIKIVGL-TEKTVLVALDTVSCLEQG-NNSRTVASTAMNSQSSRSHAIF 216
A ++++E + K+ G+ +EKT D +S +++ NS + + H +
Sbjct: 1779 AHMHLKEQQETIDKLRGIVSEKT-----DKLSNMQKDLENSNAKLQEKIQELKANEHQLI 1833
Query: 217 TIS------------LEQRKKSDKNSSFR-SKLHLVDL-------AGSERQKKTKAEGD- 255
T+ +EQ KK K+ S SKL + +L E K E D
Sbjct: 1834 TLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDN 1893
Query: 256 --RLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACV 313
R++E + + R L +L + K ++ K R+L
Sbjct: 1894 LRRVEETLKLERDQLK-----ESLQETKARDLEIQQELKTARMLS--------------- 1933
Query: 314 SPADSNLEETLNTLRYADRARKIKNKPIV-NIDPQTAELNHLKQQVQQLQVLLLQAHGGT 372
+ET++ LR + I+ I ++D EL Q++Q+ ++ LL+
Sbjct: 1934 ----KEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDV 1989
Query: 373 LPGSITVEPSENLQSLMEKN----QSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANE 428
+ E L+ E QS+ +N +L++ L E+ LE I + + +
Sbjct: 1990 NMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHES-------LEEIRIVAKERD 2042
Query: 429 KMNAKLEELRQHAACKLDLQKLVETLED----------------------QELKENVEII 466
++ E L K++ + + TL + Q L E++
Sbjct: 2043 ELRRIKESL------KMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREK 2096
Query: 467 CN-LQQLITQLS--DETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMS 523
C+ +++L+ + S D+ C+ +++ E ++E E S A + L+ +
Sbjct: 2097 CSRIKELLKRYSEMDDHYECLNRL---SLDLEKEIEFQKELSMRVKANLSLPYLQTKHIE 2153
Query: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQ 583
K + + +K+ S + I+ + ++I + E++ I+ ++++EL++++Q
Sbjct: 2154 KLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQ 2213
Query: 584 TAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMM 643
++D + R K Q ++ I ++ K +E S+ +K ++ +S R
Sbjct: 2214 HLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSE-SEFPSIKTEFQQVLSN-----RKE 2267
Query: 644 KNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRK 703
Q ++ + D EK + QK++ + Q+ R ++ F+++S + ++
Sbjct: 2268 MTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKE 2327
Query: 704 TEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRH 763
E+ + K + L K + +K L + +V +T++ K
Sbjct: 2328 WEQDLKSLKEKNEKLFKNYQT------------------LKTSLASGAQVNPTTQDNK-- 2367
Query: 764 LNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESL 823
N + R QL +K +R SL E + E I K +
Sbjct: 2368 -NPHVTSR------ATQLTTEK---------IRELENSLHEAKESAMHKESKIIK----M 2407
Query: 824 ETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCAL--KYLIGELVSSKIQV 881
+ E+E + IA LQ K+ ++ ++ ++ + +L+ K AL K E+ K+++
Sbjct: 2408 QKELEVTNDIIAKLQAKVHES---NKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKL 2464
Query: 882 SKLE-SSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQH-----QEKVLYLL 935
K++ +K +K FE+ + E Q E++R+ +++ Q + ++
Sbjct: 2465 VKIDLEKMKNAKE---------FEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVI 2515
Query: 936 SQLQQSQMAEKQLE----------------ESVSEKEQQLLSTLKCQDEELEKMR-EVCE 978
S+ Q + K L +S + ++ +S LK Q+E+L K + E+
Sbjct: 2516 SEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLS 2575
Query: 979 QNQQLLRENEIIKQKLTLLQVASRQ---KHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFL 1035
NQ L E + K++ TL + A +Q ++ PK ++ +S + + PS+ KE+ L
Sbjct: 2576 NNQHLSNEVKTWKER-TLKREAHKQVTCENSPKSPKVTGTASKK---KQITPSQCKERNL 2631
Query: 1036 EQSMDIEDLKYC 1047
+ + E K C
Sbjct: 2632 QDPVPKESPKSC 2643
Score = 66.6 bits (161), Expect = 1e-10
Identities = 144/787 (18%), Positives = 309/787 (39%), Gaps = 115/787 (14%)
Query: 331 DRARKIKNKPIVNIDPQTAELNH----LKQQVQQLQVLLLQAHGGTLPGSITVEP----- 381
D+ R I ++ I +L H LK Q ++Q L AH T++
Sbjct: 1738 DKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIV 1797
Query: 382 SENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHA 441
SE L + L N KL + E Q+ I L + NE K+ E+ Q
Sbjct: 1798 SEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQL---ITLKKDVNETQK-KVSEMEQLK 1853
Query: 442 ACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETS 501
D + LE + L ++ NL+++ + + + + +T + Q++ S
Sbjct: 1854 KQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDN--LRRVEETLKLERDQLKES 1911
Query: 502 PETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNI 561
+ +++ D Q +SKE E + L K+++ Q+ IQ +
Sbjct: 1912 LQETKARDLEIQQELKTARMLSKEHKET------VDKLREKISEKTIQISDIQKDLDKSK 1965
Query: 562 KELELEVINLQKEKEELVLELQTAKKDANQA-----------KLSERRRKRLQELEGQIA 610
EL+ ++ LQK++ L+L K+D N + K E + +Q +
Sbjct: 1966 DELQKKIQELQKKE----LQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNF 2021
Query: 611 DLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKK-- 668
L KKL+E + +++ + ++ + ++M ++Q + +R+M + Q K +K
Sbjct: 2022 QLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRL 2081
Query: 669 ----DKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREV 724
+ + + R ELLK L R + + L+ ++ Q+E+
Sbjct: 2082 LSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLD-------LEKEIEFQKEL 2134
Query: 725 ADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEK 784
+ + K S T K + N + + +++ K + V ++KE+
Sbjct: 2135 SMRVKANLSLPYLQTKHIEKLFTAN--------QRCSMEFHRIMKKLKYVLSYVTKIKEE 2186
Query: 785 KESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADL------- 837
+ N + + EV E + + +I+ L+ + + S ++ DL
Sbjct: 2187 QHESIN-----KFEMDFIDEV-----EKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMD 2236
Query: 838 ---QQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTS 894
++ L D + P + E +L + + + E ++++ + KL++ +++
Sbjct: 2237 LHIEEILKDFSESEFPSIKTE-FQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDR 2295
Query: 895 CADMQKML-------------FEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQS 941
+ FEER+ A I E + +L +++++ EK+ L+ S
Sbjct: 2296 ICQVNNFFNNRIIAIMNESTEFEERS--ATISKEWEQDLKSLKEKN-EKLFKNYQTLKTS 2352
Query: 942 QMAEKQLE----------------ESVSEKEQQLLSTL-KCQDEELEKMREVCEQNQQLL 984
+ Q+ + +EK ++L ++L + ++ + K ++ + ++L
Sbjct: 2353 LASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELE 2412
Query: 985 RENEIIKQKLTLLQVASRQKHLPKDTL--LSPDSSFEYVPPKPKPSRVKEKFLEQSMDIE 1042
N+II + + +++ K+T+ L + P K + +K K ++ +D+E
Sbjct: 2413 VTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVK--IDLE 2470
Query: 1043 DLKYCSE 1049
+K E
Sbjct: 2471 KMKNAKE 2477
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 315 bits (808), Expect = 1e-85
Identities = 296/1033 (28%), Positives = 493/1033 (47%), Gaps = 116/1033 (11%)
Query: 6 KGIPVRVALRCRPLVPKEIS-EGCQ-MCLSFVPGEPQVVVGTD--KSFTYDFVFDPSTEQ 61
+G ++V +R RP + S +G Q +CLS + + K+FT+D V D T Q
Sbjct: 23 EGDAIKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLHSNPEPKTFTFDHVADVDTTQ 82
Query: 62 EEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQL 121
E VF T +++ GYN T+ AYGQTGSGKT++M G ++ + GVIPR +
Sbjct: 83 ESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRSFEY 142
Query: 122 LFKEIDKKSD-----FEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGL 176
LF ID++ + F K S++EIYNE+I DLL A + +RE K+G+ +VG
Sbjct: 143 LFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLL--DSASAGLYLREHIKKGVFVVGA 200
Query: 177 TEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFR-SK 235
E+ V A + L G +R VAST+MN +SSRSHA+FTI++E +KS++ + R S
Sbjct: 201 VEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVNIRTSL 260
Query: 236 LHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD--DKKGGFVPYRDSKL 293
L+LVDLAGSERQK T AEG RLKE NINR L CLG VI+AL D + K V YRDSKL
Sbjct: 261 LNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHVCYRDSKL 320
Query: 294 TRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQ------ 347
T LL+DSLGGN+ T +IA V P ETL+TL +A RA+ IKNK +VN D Q
Sbjct: 321 TFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQGNVSQL 380
Query: 348 TAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSE--NLQSLMEKNQSLVEENEKLSRG 405
AE+ LK+Q+ +L A G T P S + N ++ +++E+ +
Sbjct: 381 QAEVKRLKEQLAEL------ASGQTPPESFLTRDKKKTNYMEYFQEAMLFFKKSEQEKKS 434
Query: 406 LSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEI 465
L E Q LE + L ++ + N + + R+ + L+KL + L E +
Sbjct: 435 LIEKVTQ----LEDLTLKKEKFIQSNKMIVKFREDQIIR--LEKLHKESRGGFLPEEQD- 487
Query: 466 ICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKE 525
+L+++L +E I T E Q+E P ++ + H+LR+
Sbjct: 488 -----RLLSELRNE--------IQTLRE---QIEHHPRVAKYA---MENHSLREENRRLR 528
Query: 526 LVE-LNKALALKEALARKMTQNDSQLQPI------QYQYQDNIKELELEVINLQKEKEEL 578
L+E + +A + K+ + S++ + Q + ++ N +K K +L
Sbjct: 529 LLEPVKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQL 588
Query: 579 VLELQTAKKDANQ--AKLSERRRKRLQELEGQIADLKK---------------KLNEQSK 621
L++QT ++ Q + E RKR ELE ++ L+K K E S+
Sbjct: 589 -LQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLEATKACKRQEVSQ 647
Query: 622 LLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQ--LKERD 679
L K+ T + ++ + ++ +L +M + Q D +++ +
Sbjct: 648 LNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPPEM 707
Query: 680 RKRQYELLKLE-RNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEG 738
++ +E + E R Q+Q + L+ K +E N +L+ + K + + +E S
Sbjct: 708 NEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFS----- 762
Query: 739 TAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESG--ENPPPKLR 796
+ R+ +W + E++ ++ L + L +V L+ S E KL
Sbjct: 763 -SERI-DWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLE 820
Query: 797 RRTFSLTEVR--GQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRW 854
+F + + ++SE + Q+++L E E KLL ES+ + +
Sbjct: 821 YSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENE-----------KLL--ESKACLQDSY 867
Query: 855 ENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERN----HFA 910
+N+ I +K+ I +L + K +LK + ++ + E N F
Sbjct: 868 DNLQEI------MKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFE 921
Query: 911 EIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEEL 970
E + E++++ + +++ ++ +Q ++LEES+ E+ + S K +D +
Sbjct: 922 EDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDK 981
Query: 971 EKMREVCEQNQQL 983
+ + ++ Q Q+L
Sbjct: 982 KVVADLMNQIQEL 994
Score = 68.9 bits (167), Expect = 3e-11
Identities = 139/705 (19%), Positives = 274/705 (38%), Gaps = 108/705 (15%)
Query: 322 ETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEP 381
ETL + +A ++ ++P+ + P+ L Q + L I EP
Sbjct: 654 ETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQ-----------NSSILDNDILNEP 702
Query: 382 SENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHA 441
E N+ E +S L Q + + ++ E N K+ +++L H+
Sbjct: 703 VPP-----EMNEQAFEA---ISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHS 754
Query: 442 ACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDT----AVEQEAQ 497
+Q+L + K+ E++ L L QL + + V A
Sbjct: 755 T---QMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSAD 811
Query: 498 VETSPETSRSSDAFTTQ----HALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPI 553
E S S T Q + L + M +L N L ++ L K DS
Sbjct: 812 KELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSY---- 867
Query: 554 QYQYQDNIKEL-ELEVINLQKEKEELVLELQTAKKDANQA-KLSERRRKRLQELEGQIAD 611
DN++E+ + E+ L + + E +T K D N +L E ++R +L Q +
Sbjct: 868 -----DNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEE 922
Query: 612 LKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671
K E++ + + K+ + +R K + Q +K + +K
Sbjct: 923 DK-------------ENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKV 969
Query: 672 VIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKET 731
+ L++ + + L Q+ + KTE + LKD K R+E+
Sbjct: 970 ISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREES 1029
Query: 732 QSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKE-------- 783
+ +K E++++ E + + +R +L +D+A E
Sbjct: 1030 R--------VLIKK---QEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEA 1078
Query: 784 -KKESG--ENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK 840
KK SG ++ +L ++ + E++ ++++ ++ ++E + E F+ Q+ +
Sbjct: 1079 SKKHSGLLQSAQEELTKKEALIQELQHKLNQKKE----EVEQKKNEYNFKMRQLEHVMDS 1134
Query: 841 LL-DAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQ 899
D +S P ++A +LE Q ++E + SKTS +
Sbjct: 1135 AAEDPQSPKTPPHFQTHLAKLLET----------------QEQEIEDG-RASKTSLEHLV 1177
Query: 900 KMLFEERNHFAEIETELQAELVRMEQQHQE-KVLYLLSQ--LQQSQMAEKQLEESVSEKE 956
L E+R E++ AE++RM++Q +E + L L SQ ++++ + + QL++ +KE
Sbjct: 1178 TKLNEDR----EVK---NAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKE 1230
Query: 957 QQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVAS 1001
+ Q + E+ + E+ + E++K K L +V S
Sbjct: 1231 NSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQS 1275
Score = 49.3 bits (116), Expect = 2e-05
Identities = 107/534 (20%), Positives = 222/534 (41%), Gaps = 90/534 (16%)
Query: 225 KSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGG 284
+ DK +S + L +++ E+QK+T ++ + + LL VIS+L +
Sbjct: 921 EEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDS- 979
Query: 285 FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNI 344
D K+ L + + T + D+ +E + + A + + V I
Sbjct: 980 -----DKKVVADLMNQIQ-ELRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLI 1033
Query: 345 DPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSR 404
Q ++ LK+ ++ L++L L E+L E+ L E ++K S
Sbjct: 1034 KKQEVDILDLKETLR-LRILSEDIERDML--------CEDLAHATEQLNMLTEASKKHS- 1083
Query: 405 GLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVE 464
GL ++A + ++ ++ L ++ K+N K EE+ Q K+N E
Sbjct: 1084 GLLQSAQE--ELTKKEALIQELQHKLNQKKEEVEQ--------------------KKN-E 1120
Query: 465 IICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSP--ETSRSSDAFTTQHALRQAQM 522
++QL +D+A E +T P +T + T + + +
Sbjct: 1121 YNFKMRQL------------EHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRA 1168
Query: 523 SKELVE-----LNKALALKEALARKMTQNDSQLQPIQYQYQDNIKE---LELEVINLQKE 574
SK +E LN+ +K A +M + +++ ++ + Q I++ L+ ++ +++++
Sbjct: 1169 SKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQ 1228
Query: 575 KEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVS 634
KE D N + + ++ + ++ ++A K K+ E+ +LK+K E S
Sbjct: 1229 KEN---------SDQNHPDNQQLKNEQEESIKERLA--KSKIVEE--MLKMKADLEEVQS 1275
Query: 635 KLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQ 694
L N+ ++ +R M ++ E+ Q + + Q KE+ R + E+ +
Sbjct: 1276 ALY-------NKEMECLR-MTDEVER----TQTLESKAFQEKEQLRSKLEEMYEERERTS 1323
Query: 695 KQSNVLRRKTEEAAAANKRL---KDALQKQREVADKRKETQSRGMEGTAARVKN 745
++ +LR++ E A N +L ++ QK + V +KE E R +N
Sbjct: 1324 QEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEETEKLRAEN 1377
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 311 bits (798), Expect = 2e-84
Identities = 295/1053 (28%), Positives = 499/1053 (47%), Gaps = 143/1053 (13%)
Query: 47 KSFTYDFVFDPS-------TEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMG 99
K+FTYDF F + QE VF T ++K F+GYNA V AYGQTGSGK+Y+M
Sbjct: 54 KTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMM 113
Query: 100 GAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFE---FTLKVSYLEIYNEEILDLLCPSR 156
G N G+IPR+ + LF I++ + ++ F +VSYLEIYNE + DLL
Sbjct: 114 G-------NSGDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKS 166
Query: 157 EKA-QINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAI 215
K + +RE PKEG + L++ V D ++ GN +RT A+T MN SSRSHAI
Sbjct: 167 SKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAI 226
Query: 216 FTISLEQRK-KSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVI 274
FTI Q K S+ SK+HLVDLAGSER T A G RLKEG NIN+ L+ LGNVI
Sbjct: 227 FTIKFTQAKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVI 286
Query: 275 SALGD----------DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETL 324
SAL D KK FVPYRDS LT LL+DSLGGNS T+MIA +SPAD N ETL
Sbjct: 287 SALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETL 346
Query: 325 NTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSEN 384
+TLRYA+RA+ I NKP +N D + L+ ++ +L+ LL Q + L S T + +
Sbjct: 347 STLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPT---ALS 403
Query: 385 LQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILT---EQANEKMNAKLEEL---- 437
++ +++N++ V+E L++ + +T +L+ L E ++++L L
Sbjct: 404 MEEKLQQNEARVQE---LTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGID 460
Query: 438 ---------------------RQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQL 476
R A+ + D+ L +L+ I N+ +T +
Sbjct: 461 DDLLSTGIILYHLKEGQTYVGRDDASTEQDI-----VLHGLDLESEHCIFENIGGTVTLI 515
Query: 477 SDETVACMAAAID----TAVEQEAQV--------------ETSPETSRSSDAFTTQHALR 518
C + T + Q A + E + + + +L
Sbjct: 516 PLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLS 575
Query: 519 QAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEEL 578
+SK L+ + L + Q + +L+ ++ + + I+E+E + + + E E +
Sbjct: 576 MTDLSKSRENLSAVMLYNPGLEFERQQRE-ELEKLESK-RKLIEEMEEKQKSDKAELERM 633
Query: 579 VLELQTAKKDANQAKLSERR-----RKRLQELEGQIADL--------KKKLNEQSKL-LK 624
E++T +K+ +L R+ ++R +E ++ DL +++L EQ ++ L+
Sbjct: 634 QQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQ 693
Query: 625 LKESTERTVSKLNQEIRMMKN-------QRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKE 677
K E T ++ +E++ +K ++ Q+ +++ + ++ + K + E +L+E
Sbjct: 694 KKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEE 753
Query: 678 RDRKRQYELLKLE---RNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSR 734
+++++ + LE R Q+ +LRR + KR L+ RE + KE ++
Sbjct: 754 QEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKR---DLEGIRESLLRVKEARAG 810
Query: 735 G------MEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESG 788
G +E R + ++ +V+ E+ DL++ + IL ++V + +E E
Sbjct: 811 GDEDGEELEKAQLRFFEFKRRQLVKLVNLEK------DLVQQKDILKKEVQEEQEILECL 864
Query: 789 ENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDA---- 844
+ K R E V+E K I+ +E ++++ Q+ L Q L
Sbjct: 865 KCEHDKESRLLEKHDESVTDVTEVPQDFEK-IKPVEYRLQYKERQLQYLLQNHLPTLLEE 923
Query: 845 -----ESEDRPKQRWENIATILEAKCALK-YLIGELVSSKIQVSKLESSLKQSKTSCADM 898
E DR +N +E + K + + ++ Q+ KL+++ + +
Sbjct: 924 KQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQE 983
Query: 899 QKMLFEERNHFAEIETE----LQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSE 954
+K+ +E+ E + L+ L R+E++H + ++ + +K +
Sbjct: 984 EKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGS 1043
Query: 955 KEQQ-LLSTLKCQDEELEKMREVCEQNQQLLRE 986
+EQ L ++L+ + E LEK +E E Q L++
Sbjct: 1044 REQSGLQASLEAEQEALEKDQERLEYEIQQLKQ 1076
Score = 78.6 bits (192), Expect = 3e-14
Identities = 115/500 (23%), Positives = 220/500 (44%), Gaps = 66/500 (13%)
Query: 519 QAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEEL 578
+ Q +EL +L L E + K + ++L+ +Q + + KE E+ + ++K++E L
Sbjct: 599 ERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESL 658
Query: 579 V---LELQTAKKD--ANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTV 633
++ KD A + K E R + QE+E L+KK E+ L+++E +R +
Sbjct: 659 KRRSFHIENKLKDLLAEKEKFEEERLREQQEIE-----LQKKRQEEETFLRVQEELQR-L 712
Query: 634 SKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLE--- 690
+LN + K Q Q + Q+++ EK Q+ K + E +L+E+++++ + LE
Sbjct: 713 KELNNNEKAEKFQIFQELDQLQK--EKDEQYA-KLELEKKRLEEQEKEQVMLVAHLEEQL 769
Query: 691 RNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRG------MEGTAARVK 744
R Q+ +LRR + KR L+ RE + KE ++ G +E R
Sbjct: 770 REKQEMIQLLRRGEVQWVEEEKR---DLEGIRESLLRVKEARAGGDEDGEELEKAQLRFF 826
Query: 745 NWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTE 804
+ ++ +V+ E+ DL++ + IL ++V + +E E + K R E
Sbjct: 827 EFKRRQLVKLVNLEK------DLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDE 880
Query: 805 VRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAK 864
V+E K I+ +E ++++ Q+ L Q L E++ + IL+
Sbjct: 881 SVTDVTEVPQDFEK-IKPVEYRLQYKERQLQYLLQNHLPTLLEEK-----QRAFEILDR- 933
Query: 865 CALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRME 924
L L + ++ + E L Q + + +QK+ + E A + R E
Sbjct: 934 -GPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKL---------QATFEFTANIARQE 983
Query: 925 QQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLL 984
++ ++K EK++ ES +E+Q L+ LE+ +++ L
Sbjct: 984 EKVRKK--------------EKEILES---REKQQREALERALARLERRHSALQRHSTLG 1026
Query: 985 RENEIIKQKLTLLQVASRQK 1004
E E +QKL L SR++
Sbjct: 1027 MEIEEQRQKLASLNSGSREQ 1046
Score = 38.1 bits (87), Expect = 0.052
Identities = 79/370 (21%), Positives = 152/370 (41%), Gaps = 59/370 (15%)
Query: 322 ETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEP 381
E + D+ +K K++ + EL + + Q+ + ++L AH L + E
Sbjct: 722 EKFQIFQELDQLQKEKDEQYAKL-----ELEKKRLEEQEKEQVMLVAH---LEEQLR-EK 772
Query: 382 SENLQSLMEKNQSLVEENEKLSRGLSEA----------AGQTAQMLERIILTE-QANEKM 430
E +Q L VEE ++ G+ E+ + + LE+ L + +
Sbjct: 773 QEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQ 832
Query: 431 NAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDT 490
KL L + + D+ K E E+QE+ E ++ + + + + DE+V + +
Sbjct: 833 LVKLVNLEKDLVQQKDILKK-EVQEEQEILECLKCEHDKESRLLEKHDESVTDVTE-VPQ 890
Query: 491 AVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKE----------------LVELNKALA 534
E+ VE + + Q+ L K+ L ++ K +
Sbjct: 891 DFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEME 950
Query: 535 LKEALARKMTQNDSQLQPIQ--YQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQA 592
KE + N +QLQ +Q +++ NI E +V +K+++E++ + +++A +
Sbjct: 951 EKEEQLAQYQANANQLQKLQATFEFTANIARQEEKV---RKKEKEILESREKQQREALER 1007
Query: 593 KLS--ERRRKRLQ-------ELEGQ---IADLKKKLNEQS----KLLKLKESTERTVSKL 636
L+ ERR LQ E+E Q +A L EQS L +E+ E+ +L
Sbjct: 1008 ALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERL 1067
Query: 637 NQEIRMMKNQ 646
EI+ +K +
Sbjct: 1068 EYEIQQLKQK 1077
Score = 37.4 bits (85), Expect = 0.089
Identities = 62/301 (20%), Positives = 135/301 (44%), Gaps = 37/301 (12%)
Query: 759 EAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITK 818
E+KR L + +E+++ D A+L+ ++ E +R+ + ++ Q+ + E+S+ +
Sbjct: 610 ESKRKLIEEMEEKQ--KSDKAELERMQQEVET-----QRKETEIVQL--QIRKQEESLKR 660
Query: 819 QIESLETEMEFRSAQIADLQQKLLDAESE---DRPKQRWENIATILEAKCALKYLIGELV 875
+ +E +++ A+ +++ L + E + +Q E + E LK L
Sbjct: 661 RSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEK 720
Query: 876 SSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEK--VLY 933
+ K Q+ + L++ K + L E+ E E E + +E+Q +EK ++
Sbjct: 721 AEKFQIFQELDQLQKEKD---EQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQ 777
Query: 934 LLSQLQQSQMAEKQLE-ESVSEKEQQLLSTLKCQD---EELEK--MREVCEQNQQLLR-- 985
LL + + + E++ + E + E ++ D EELEK +R + +QL++
Sbjct: 778 LLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLV 837
Query: 986 --ENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQSMDIED 1043
E ++++QK L + ++ + + D K SR+ EK E D+ +
Sbjct: 838 NLEKDLVQQKDILKKEVQEEQEILECLKCEHD----------KESRLLEKHDESVTDVTE 887
Query: 1044 L 1044
+
Sbjct: 888 V 888
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 308 bits (789), Expect = 2e-83
Identities = 169/347 (48%), Positives = 220/347 (63%), Gaps = 9/347 (2%)
Query: 9 PVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTA 68
PVRVALR RPL+PKE+ G Q CL PG +V +G D+ F + V QE V+
Sbjct: 15 PVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQAC 74
Query: 69 VAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDK 128
V PL++ F+G+NATV AYGQTGSGKTY+MG A A E G++PR + FK ID+
Sbjct: 75 VQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASL-LEDEQGIVPRAMAEAFKLIDE 133
Query: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
+ + VSYLE+Y EE DLL I +RED + + + G+ E V + +
Sbjct: 134 NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDEVL 193
Query: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDK-------NSSFRSKLHLVDL 241
S LE GN +R +T +N SSRSH +FT++LEQR ++ SK H VDL
Sbjct: 194 SLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSKFHFVDL 253
Query: 242 AGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-DKKGGFVPYRDSKLTRLLQDS 300
AGSER KT + G+RLKE I IN LL LGNVISALGD ++G +PYRDSK+TR+L+DS
Sbjct: 254 AGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDS 313
Query: 301 LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQ 347
LGGN+ T+MIACVSP+ S+ +ETLNTL YA RA+ I+N+ VN P+
Sbjct: 314 LGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPE 360
Score = 116 bits (290), Expect = 2e-25
Identities = 117/517 (22%), Positives = 236/517 (45%), Gaps = 78/517 (15%)
Query: 518 RQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEE 577
R AQ +++ EL + +KE L ++ + Q + Q+ I+ELE E ++ E E
Sbjct: 702 RLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSE 761
Query: 578 LVLELQTAK----KDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTV 633
+L+ + +DA + + R+R+ + Q+ LK+K +L+ L +E+ +
Sbjct: 762 GQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRL 821
Query: 634 SKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNF 693
+L + +++M+ Q+ QL R+++E+ E+ R +L+ KRQ+ + +LE
Sbjct: 822 QELERNVQLMRQQQGQLQRRLREETEQKR-----------RLEAEMSKRQHRVKELELKH 870
Query: 694 QKQSNVLRRKTEEAAAANKRLKD-------ALQKQREVADKRKETQSRGMEGTAARVKNW 746
++Q +L+ KTEE AA ++ + +L++Q+++ +++K W
Sbjct: 871 EQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKK----------------W 914
Query: 747 LGNEIEVMVSTEEAKRHLNDLLEDRK-ILAQDVAQLKEKKESGENPPPKLRRRTFSLTEV 805
L E+E ++ A L + L R+ ILA+ A ++EK +
Sbjct: 915 LDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEK-------------TGLESKRL 961
Query: 806 RGQVSESED--SITKQIESLETEMEFRSAQI----ADLQQKL------LDAESEDRPKQR 853
R + +ED ++ ++E LE E+ +S Q+ A QQ++ L E + KQR
Sbjct: 962 RSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQR 1021
Query: 854 WENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIE 913
E + + L + L+++++ + Q++L + ++ E
Sbjct: 1022 LEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCE 1081
Query: 914 TELQAELVRMEQ--------QHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKC 965
L A+L + ++ +KV+ L + Q Q+A +LE + E++Q+L+ L
Sbjct: 1082 MNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQL-EEQQRLVYWL-- 1138
Query: 966 QDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASR 1002
E+ R+ E ++QL + + +Q + LL SR
Sbjct: 1139 ---EVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSR 1172
Score = 56.2 bits (134), Expect = 2e-07
Identities = 107/588 (18%), Positives = 238/588 (40%), Gaps = 121/588 (20%)
Query: 411 GQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQ 470
G+ AQ L R Q ++++ +E Q A + Q+ + LE +EL++ E LQ
Sbjct: 731 GKAAQALNR-----QHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGER-SRLQ 784
Query: 471 QLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELN 530
+ ++ AAA ++QV+ E ++++ + AQ K L EL
Sbjct: 785 EFRRRV--------AAA-------QSQVQVLKEKKQATERLVSL----SAQSEKRLQELE 825
Query: 531 KALALK-------EALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQ 583
+ + L + R+ T+ +L+ + Q +KELE L+ E+++ +L+++
Sbjct: 826 RNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELE-----LKHEQQQKILKIK 880
Query: 584 TAKKDANQAKLSERRRKRLQELEGQIADL--KKKLNEQSKLLKLKESTERTVSKLNQEIR 641
T + A Q RKR G + L ++K+ EQ K L+QE+
Sbjct: 881 TEEIAAFQ-------RKRRSGSNGSVVSLEQQQKIEEQKKW-------------LDQEME 920
Query: 642 MMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLR 701
+ QR + + +L E KR+ L K E Q+++ +
Sbjct: 921 KVLQQR----------------------RALEELGEELHKREAILAKKEALMQEKTGLES 958
Query: 702 RKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAK 761
++ + A N+ + + + + E + +G+A S ++ +
Sbjct: 959 KRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQ--------------SQQQIR 1004
Query: 762 RHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIE 821
++ L +++ L + ++ K G P+ R F L E IE
Sbjct: 1005 GEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEA--------------IE 1050
Query: 822 SLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATI-----LEAKCALKYLIGELVS 876
+L+ +E+++ I +Q++L A + + +A + E + L ++V+
Sbjct: 1051 ALDAAIEYKNEAIT-CRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVT 1109
Query: 877 SKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLS 936
+ + + + + + + + Q++++ E+ +L +++H++ + LL
Sbjct: 1110 LREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLL- 1168
Query: 937 QLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLL 984
Q + L E +++ +Q + ++ ++EL + + ++ +Q L
Sbjct: 1169 -----QQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKL 1211
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 299 bits (766), Expect = 1e-80
Identities = 219/624 (35%), Positives = 327/624 (52%), Gaps = 56/624 (8%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVG-TD------KSFTYDFVFDPSTEQE 62
V+V +RCRPL +E S + +S + V TD K+FT+D VF P ++Q
Sbjct: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
Query: 63 EVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLL 122
+V+N P+I V +GYN T+ AYGQTG+GKT++M G + G+IP +
Sbjct: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR----GIIPNSFAHI 130
Query: 123 FKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTV 181
F I K + D F ++VSYLEIYNEE+ DLL + + ++ ++E P G+ I L+ V
Sbjct: 131 FGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQ-RLEVKERPDVGVYIKDLSAYVV 189
Query: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKS-DKNSSFR-SKLHLV 239
A D + G+ +R+V +T MN SSRSHAIFTI++E +K D N R KLHLV
Sbjct: 190 NNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLV 249
Query: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQD 299
DLAGSERQ KT A G RLKE IN L LGNVISAL D K VPYR+SKLTRLLQD
Sbjct: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKST-HVPYRNSKLTRLLQD 308
Query: 300 SLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQ 359
SLGGNS T+M A + PAD N +ET++TLRYA+RA+ IKNK +N DP+ A L +++++
Sbjct: 309 SLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIE 368
Query: 360 QLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLER 419
+L+ L G + GS E+ ++ + E+ EK + + +M+E
Sbjct: 369 ELKKKL--EEGEEISGSDISGSEED----DDEEGEVGEDGEKRKKRRGKKKVSPDKMIE- 421
Query: 420 IILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDE 479
M AK++E R+ KLD+++ EL++ + + QQ L ++
Sbjct: 422 ----------MQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEK 471
Query: 480 TVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEAL 539
A I V+ A+ E + S+ +EL + E L
Sbjct: 472 LSALEKKVIVGGVDLLAKAEEQEKLLEESN-----------------MELEERRKRAEQL 514
Query: 540 ARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRR 599
R++ + + + I+ +Y L+ E K+ +++ L AK + A L + +
Sbjct: 515 RRELEEKEQERLDIEEKY----TSLQEEAQGKTKKLKKVWTMLMAAKSE--MADLQQEHQ 568
Query: 600 KRLQELEGQIADLKKKLNEQSKLL 623
+ ++ L I L ++L Q ++
Sbjct: 569 REIEGLLENIRQLSRELRLQMLII 592
Score = 47.8 bits (112), Expect = 7e-05
Identities = 91/475 (19%), Positives = 183/475 (38%), Gaps = 78/475 (16%)
Query: 382 SENLQSLMEKNQSL-VEENEKLSRG-----LSEAAGQTAQMLERIILTEQANEKMNAKLE 435
+E ++ L+ K+Q+ +E E+ G LS A ++RI+ N + A
Sbjct: 154 NEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGAT-- 211
Query: 436 ELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQE 495
+ +H++ + + ++ + N+ + L+ E A A +++
Sbjct: 212 NMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGSERQA-KTGATGQRLKEA 270
Query: 496 AQVETSPET-----SRSSDAFTTQHALRQAQMSKELVELNKALALKEALA-RKMTQNDSQ 549
++ S T S D +T R +++++ L+++L T +
Sbjct: 271 TKINLSLSTLGNVISALVDGKSTHVPYRNSKLTR---------LLQDSLGGNSKTMMCAN 321
Query: 550 LQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRL-QELEGQ 608
+ P Y Y + I L AK N+A+++E + L ++ + +
Sbjct: 322 IGPADYNYDETISTLRYA---------------NRAKNIKNKARINEDPKDALLRQFQKE 366
Query: 609 IADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKK 668
I +LKKKL E ++ S E+ ED EK ++ + KK
Sbjct: 367 IEELKKKLEEGEEISGSDISGSEEDDDEEGEVG--------------EDGEKRKKRRGKK 412
Query: 669 DKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKR 728
++ E K E LE + + + A KR KD L+ Q+E
Sbjct: 413 KVSPDKMIEMQAKIDEERKALETKLDMEEE---ERNKARAELEKREKDLLKAQQE----- 464
Query: 729 KETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDL---LEDRKILAQDVAQLKEKK 785
+E +A K + ++++ EE ++ L + LE+R+ A+ + + E+K
Sbjct: 465 ---HQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK 521
Query: 786 ESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK 840
E + + E + E TK+++ + T + +++ADLQQ+
Sbjct: 522 E----------QERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQE 566
Score = 37.0 bits (84), Expect = 0.12
Identities = 53/236 (22%), Positives = 105/236 (44%), Gaps = 38/236 (16%)
Query: 775 AQDVAQLKEKKESGENPPPKLRRR-TFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQ 833
A +K K E+P L R+ + E++ ++ E E+ I E +
Sbjct: 339 ANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEED------- 391
Query: 834 IADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKT 893
D ++ + + E R K+R G+ S ++ ++++ + + +
Sbjct: 392 --DDEEGEVGEDGEKRKKRR------------------GKKKVSPDKMIEMQAKIDEERK 431
Query: 894 SCADMQKMLFEERNHF-AEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESV 952
+ M EERN AE+E + +L++ +Q+HQ +L LS L++ + +
Sbjct: 432 ALETKLDMEEEERNKARAELEKR-EKDLLKAQQEHQ-SLLEKLSALEKKVIVGGVDLLAK 489
Query: 953 SEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENE----IIKQKLTLLQVASRQK 1004
+E++++LL + ELE+ R+ EQ ++ L E E I++K T LQ ++ K
Sbjct: 490 AEEQEKLLEE---SNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGK 542
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 299 bits (766), Expect = 1e-80
Identities = 195/535 (36%), Positives = 296/535 (55%), Gaps = 34/535 (6%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTD-------KSFTYDFVFDPSTEQE 62
V+V +RCRP+ +E CQ ++ Q + K FT+D + E
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 63 EVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLL 122
+++N PL++GV +GYN T+ AYGQTGSGK+++M G + G+IPR + +
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR----GIIPRAFEHV 121
Query: 123 FKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVL 182
F+ + + +F ++ SYLEIYNE++ DLL + K ++ ++E P++G+ + GL+ TV
Sbjct: 122 FESVQCAENTKFLVRASYLEIYNEDVRDLL-GADTKQKLELKEHPEKGVYVKGLSMHTVH 180
Query: 183 VALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSF--RSKLHLVD 240
+E G +R+V T MN SSRSH+IFTIS+E ++ KL+LVD
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD 240
Query: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDS 300
LAGSERQ KT A G+RLKE IN L LGNVISAL D + VPYRDSKLTRLLQDS
Sbjct: 241 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK-HVPYRDSKLTRLLQDS 299
Query: 301 LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQ 360
LGGN+ TLM+AC+SPAD+N +ETL+TLRYA+RA+ I+NKP +N DP+ A L ++++++
Sbjct: 300 LGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKK 359
Query: 361 LQVLLLQ-----AHGGTLPGSITVEPSENLQSLMEKN--QSLVEENEKLSRGLSEAAGQT 413
L+ +L Q + L + +P + + L+ + Q VE ++L R E
Sbjct: 360 LKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAEKQLIREEYE----- 414
Query: 414 AQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLI 473
+ L R+ +A ++ A+LEE A + + TLE+ KE ++
Sbjct: 415 -ERLARLKADYKAEQESRARLEE--DITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYK 471
Query: 474 TQLSDETVACMAAAIDTAVEQEAQVE----TSPETSRSSDAFTTQHALRQAQMSK 524
++ +A A + E V+ ++ +T S D TQ + R A++ K
Sbjct: 472 AEVMSRAEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAELPK 526
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 299 bits (766), Expect = 1e-80
Identities = 195/535 (36%), Positives = 296/535 (55%), Gaps = 34/535 (6%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTD-------KSFTYDFVFDPSTEQE 62
V+V +RCRP+ +E CQ ++ Q + K FT+D + E
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 63 EVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLL 122
+++N PL++GV +GYN T+ AYGQTGSGK+++M G + G+IPR + +
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR----GIIPRAFEHV 121
Query: 123 FKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVL 182
F+ + + +F ++ SYLEIYNE++ DLL + K ++ ++E P++G+ + GL+ TV
Sbjct: 122 FESVQCAENTKFLVRASYLEIYNEDVRDLL-GADTKQKLELKEHPEKGVYVKGLSMHTVH 180
Query: 183 VALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSF--RSKLHLVD 240
+E G +R+V T MN SSRSH+IFTIS+E ++ KL+LVD
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD 240
Query: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDS 300
LAGSERQ KT A G+RLKE IN L LGNVISAL D + VPYRDSKLTRLLQDS
Sbjct: 241 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK-HVPYRDSKLTRLLQDS 299
Query: 301 LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQ 360
LGGN+ TLM+AC+SPAD+N +ETL+TLRYA+RA+ I+NKP +N DP+ A L ++++++
Sbjct: 300 LGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKK 359
Query: 361 LQVLLLQ-----AHGGTLPGSITVEPSENLQSLMEKN--QSLVEENEKLSRGLSEAAGQT 413
L+ +L Q + L + +P + + L+ + Q VE ++L R E
Sbjct: 360 LKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAEKQLIREEYE----- 414
Query: 414 AQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLI 473
+ L R+ +A ++ A+LEE A + + TLE+ KE ++
Sbjct: 415 -ERLARLKADYKAEQESRARLEE--DITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYK 471
Query: 474 TQLSDETVACMAAAIDTAVEQEAQVE----TSPETSRSSDAFTTQHALRQAQMSK 524
++ +A A + E V+ ++ +T S D TQ + R A++ K
Sbjct: 472 AEVMSRAEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAELPK 526
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 290 bits (742), Expect = 6e-78
Identities = 262/958 (27%), Positives = 454/958 (47%), Gaps = 94/958 (9%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAV 69
++V R RPL E++ G + F GE VV+ + K + +D VF ST QE+V+N
Sbjct: 9 IKVMCRFRPLNESEVNRGDKYIAKF-QGEDTVVIAS-KPYAFDRVFQSSTSQEQVYNDCA 66
Query: 70 APLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEI-DK 128
++K V +GYN T+ AYGQT SGKT++M G + + +G+IPR++Q +F I
Sbjct: 67 KKIVKDVLEGYNGTIFAYGQTSSGKTHTMEG----KLHDPEGMGIIPRIVQDIFNYIYSM 122
Query: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
+ EF +KVSY EIY ++I DLL S K +++ ED + G TE+ V + +
Sbjct: 123 DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLSVHEDKNRVPYVKGCTERFVCSPDEVM 180
Query: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQK 248
+++G ++R VA T MN SSRSH+IF I+++Q + + KL+LVDLAGSE+
Sbjct: 181 DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQ-ENTQTEQKLSGKLYLVDLAGSEKVS 239
Query: 249 KTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTL 308
KT AEG L E NIN+ L LGNVISAL + +VPYRDSK+TR+LQDSLGGN T
Sbjct: 240 KTGAEGAVLDEAKNINKSLSALGNVISALAEGST--YVPYRDSKMTRILQDSLGGNCRTT 297
Query: 309 MIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQA 368
++ C SP+ N ET +TL + RA+ IKN VN++ TAE K + ++ + +L+
Sbjct: 298 IVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVE-LTAEQWKKKYEKEKEKNKILRN 356
Query: 369 HGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANE 428
T++ EN + +N V +E+ + E A A +++ I N+
Sbjct: 357 ---------TIQWLEN-ELNRWRNGETVPIDEQFDK---EKANLEAFTVDKDITL--TND 401
Query: 429 KMNAKLEEL-----RQHAACKLDLQKLVETLE--DQELKENVEIICNLQQLITQLSDETV 481
K + + + C+ ++ KL + L+ D+E+ + +++ ++L TQ+ D
Sbjct: 402 KPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLV---EKLKTQMLD--- 455
Query: 482 ACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALAR 541
Q E T R D + QA+ E+ + L E LA
Sbjct: 456 ---------------QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAV 500
Query: 542 KMTQNDSQLQPIQYQYQ---DNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERR 598
Q +++ +Y+ D + + + ++ E ++L KK A A++
Sbjct: 501 NYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRA--AEMMASL 558
Query: 599 RKRLQELEGQIADLKKKLNEQSKLLKLKESTERT-VSKLNQEIRMMKNQRVQLMRQMKED 657
K L E+ + + K E + ++ + + R +SK+ E++ M + QL E
Sbjct: 559 LKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTES 618
Query: 658 AEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDA 717
+K ++ +KE+ + R + + ++ L Q R+ E A ++ L
Sbjct: 619 NKKM----EENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQ- 673
Query: 718 LQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTE-----------EAKRHL-N 765
L+ Q +V + KE ++ TA VK + +I+ T EAK L
Sbjct: 674 LRAQEKVHEMEKEHLNKVQ--TANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLIT 731
Query: 766 DLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLT-------EVRGQVSESEDSITK 818
DL + + + + +L+ + E + + R+ LT + R + E+++ K
Sbjct: 732 DLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAK 791
Query: 819 QIESLETEMEFRSAQIADLQQKLLDAESED-----RPKQRWENIATILEAKCAL-KYLIG 872
++++L + +A +K + +S+D KQ+ + LE + K L+
Sbjct: 792 ELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVR 851
Query: 873 ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEK 930
+ + ++ KLE L+ + ++ L E + + + Q E+ R+++ + K
Sbjct: 852 DNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSK 909
Score = 69.7 bits (169), Expect = 2e-11
Identities = 83/373 (22%), Positives = 162/373 (43%), Gaps = 47/373 (12%)
Query: 663 QWKQKKDKEVIQLK-----------ERDRKRQYELLKLERNFQKQSNVLRRKT--EEAAA 709
QWK+K +KE + K E +R R E + ++ F K+ L T ++
Sbjct: 339 QWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITL 398
Query: 710 ANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGN-EIEVMVSTEEAKRHLNDLL 768
N + A+ V + + R E A++ L + + E+ ++ ++ +L
Sbjct: 399 TNDKPATAIG----VIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQML 454
Query: 769 EDRKILA-----QDVAQLKEKKESGENPPPK--LRRRTFSLTEVR---GQVSESEDSITK 818
+ ++LA QD Q + + EN K ++ +L E+ Q S+ + TK
Sbjct: 455 DQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTK 514
Query: 819 QIESLETEMEFRSAQIADLQQKL--LDAESEDRPKQRWENIATILEAKCALKYLIG---- 872
+ E L E+ +SA +A + +L L + + K+ E +A++L+ + +G
Sbjct: 515 EYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDV 574
Query: 873 -----------ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELV 921
E +++ +SK++S +K C ++ E E E EL A +
Sbjct: 575 KQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQL 634
Query: 922 RMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQ 981
R+ Q H+ K+ L LQ + ++QLEESV ++L+ L+ Q++ E +E + Q
Sbjct: 635 RISQ-HEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQ-LRAQEKVHEMEKEHLNKVQ 692
Query: 982 QLLRENEIIKQKL 994
+ ++Q++
Sbjct: 693 TANEVKQAVEQQI 705
Score = 61.2 bits (147), Expect = 6e-09
Identities = 91/510 (17%), Positives = 216/510 (42%), Gaps = 44/510 (8%)
Query: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQ 583
+E+ +L K L K+ + +Q +L+ ++ + + N+Q E L E
Sbjct: 423 EEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAEND 482
Query: 584 TAKKDANQA-----KLSERRRKRLQELEGQIAD---LKKKLNEQSKLLKLKESTERTVSK 635
+K++ + +L+ ++ QE+E + + L +LN++S L S + + K
Sbjct: 483 ASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLA---SIDAELQK 539
Query: 636 LNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQK 695
L + K + ++M + +D + I + D K+ ++ F
Sbjct: 540 LKEMTNHQKKRAAEMMASLLKDLAEIG----------IAVGNNDVKQPEGTGMIDEEFTV 589
Query: 696 QSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNW---LGNEIE 752
+ + E KR K Q E ++K+ E + + R+ + + E
Sbjct: 590 ARLYISKMKSEVKTMVKRCKQLESTQTE-SNKKMEENEKELAACQLRISQHEAKIKSLTE 648
Query: 753 VMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRR-RTFSLTE--VRGQV 809
+ + E+ KR L + ++ L++++ QL+ +++ E L + +T + + V Q+
Sbjct: 649 YLQNVEQKKRQLEESVD---ALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQI 705
Query: 810 SESEDSITKQIESLETEMEFRSAQIADLQ---QKLLDAESEDRPKQRWENIATILEAKCA 866
++ KQI SL E+E ++ I DLQ QK++ ++R + E + + K
Sbjct: 706 QSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMM--LEQERLRVEHEKLKATDQEKSR 763
Query: 867 LKYLIGELVSSKIQVSK----LESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVR 922
+ + + + Q + LE ++ + + +++K+ ++ + E+ ++
Sbjct: 764 KLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTG 823
Query: 923 MEQQHQEKVLYLLSQLQQSQMAEKQLEESVSE---KEQQLLSTLKCQDEELEKMREVC-E 978
++K+ +L + L+Q KQL ++ + +L L+ E ++ + E
Sbjct: 824 GSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKE 883
Query: 979 QNQQLLRENEIIKQKLTLLQVASRQKHLPK 1008
+ R+ + +Q++ ++ A R K++ +
Sbjct: 884 AKENASRDRKRYQQEVDRIKEAVRSKNMAR 913
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 284 bits (726), Expect = 4e-76
Identities = 251/936 (26%), Positives = 433/936 (46%), Gaps = 72/936 (7%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAV 69
++V R RPL EI G + F G+ VV+G K + +D V P+T QE+V+N
Sbjct: 9 IKVMCRFRPLNEAEILRGDKFIPKF-KGDETVVIGQGKPYVFDRVLPPNTTQEQVYNACA 67
Query: 70 APLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEI-DK 128
++K V +GYN T+ AYGQT SGKT++M G Q +G+IPR+ +F I
Sbjct: 68 KQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGIIPRIAHDIFDHIYSM 123
Query: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
+ EF +KVSY EIY ++I DLL S K + + ED + G TE+ V + +
Sbjct: 124 DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181
Query: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQK 248
+++G +R VA T MN SSRSH+IF I+++Q + + KL+LVDLAGSE+
Sbjct: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ-ENVETEKKLSGKLYLVDLAGSEKVS 240
Query: 249 KTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTL 308
KT AEG L E NIN+ L LGNVISAL + K VPYRDSK+TR+LQDSLGGN T
Sbjct: 241 KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKT-HVPYRDSKMTRILQDSLGGNCRTT 299
Query: 309 MIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNH-----------LKQQ 357
++ C SP+ N ET +TL + RA+ IKN VN++ E LK
Sbjct: 300 IVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNV 359
Query: 358 VQQLQVLLLQ-AHGGTLPGS--ITVEPSENLQS-----LMEKNQSLV-----EENEKLSR 404
+Q L++ L + +G +P I+ + +NL+ +++ +V EE EK
Sbjct: 360 IQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDE 419
Query: 405 GLSEAAGQTAQMLERIILTEQANEKMNAK-LEELRQHAACKLDLQKLVETLEDQELKENV 463
+S Q + I Q EK+ + L++ A+ + D +K+ E L +++
Sbjct: 420 EISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEA 479
Query: 464 EIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMS 523
DE + A + AV + + + + +R+++ T + A + ++
Sbjct: 480 A------------KDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLT 527
Query: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEV---INLQKEKEELVL 580
EL++ L ++ T+ + L + I +++ +N E+E +
Sbjct: 528 TTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMA 587
Query: 581 ELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLK----LKESTERTVSKL 636
L +K + L R + +LE D +K+N + L L E + L
Sbjct: 588 RLYISKMKSEVKSLVNRSK----QLESAQMDSNRKMNASERELAACQLLISQHEAKIKSL 643
Query: 637 NQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQ 696
++ M+ +R QL +E+ + + ++ + ++++++ L E +
Sbjct: 644 TDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKAL 703
Query: 697 SNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVS 756
+ E RL+D +++++++ D+ ++ + ++ N++++
Sbjct: 704 EQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDY--NKLKIEDQ 761
Query: 757 TEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSI 816
E K LL D++ A++ + E+ S E R+ F +D
Sbjct: 762 EREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFV-----------QDLT 810
Query: 817 TKQIESLETEMEFRSAQIADLQQ-KLLDAESEDRPKQRWENIATILEAKCALKYLIGELV 875
T+ +S+E + + A Q+ L+ E K + + + +C L L L
Sbjct: 811 TRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLR 870
Query: 876 SSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAE 911
++ +V LES+LK++K + +K +E + E
Sbjct: 871 ATAERVKALESALKEAKENAMRDRKRYQQEVDRIKE 906
Score = 67.8 bits (164), Expect = 6e-11
Identities = 96/460 (20%), Positives = 192/460 (41%), Gaps = 51/460 (11%)
Query: 573 KEKEELVLELQTAKKDANQAKLSERRRKRLQEL---EGQIADLKKKLNEQSKLLKLKEST 629
K+K E E K+ Q E R R E + QI+ +K E + ++
Sbjct: 343 KKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNI 402
Query: 630 ERTVSKLNQEIRMMKNQRVQ-LMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLK 688
V+ ++ E + ++ + L RQ+ + ++ Q Q +K Q+ ++D L
Sbjct: 403 APVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDEL----LAS 458
Query: 689 LERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAA--RVKNW 746
R+++K L R E AA +K+ LQ E+A + + T A ++ +
Sbjct: 459 TRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDE 518
Query: 747 LGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVR 806
L + + +T+ L +L +K A ++ L K+ GE +L +V
Sbjct: 519 LAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLL-LKDLGEIGGIIGTNDVKTLADVN 577
Query: 807 GQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCA 866
G + E I +++E++ + L+ +D+ + +R
Sbjct: 578 GVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASER------------- 624
Query: 867 LKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQ 926
EL + ++ +S+ E+ +K S D + + ++R E + L EL ++ Q
Sbjct: 625 ------ELAACQLLISQHEAKIK----SLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQ 674
Query: 927 H-------QEKVLYLLSQLQQSQMAEKQLE---ESVSEKEQQLLSTLKCQDEELEKMREV 976
Q+K L++LQ ++ +K LE ES E Q+ LS L+ +E+E+ +++
Sbjct: 675 EKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLR---DEIEEKQKI 731
Query: 977 CEQ----NQQLLRENEIIKQKLTLLQVASRQKHLPKDTLL 1012
++ NQ+L E E + L++ +++ + + LL
Sbjct: 732 IDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLL 771
Score = 53.9 bits (128), Expect = 9e-07
Identities = 108/540 (20%), Positives = 238/540 (44%), Gaps = 70/540 (12%)
Query: 490 TAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQ 549
TA E + + E E ++ T ++ ++ +M +A+ E ++ K +N
Sbjct: 338 TAEEWKKKYEKEKEKNK-----TLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKN--- 389
Query: 550 LQPIQYQ-YQDNIKELELEVINLQKEKEE-----LVLELQTAKKDANQ-AKLSERRRKRL 602
L+P DNI + + +KEK + L +L + NQ ++L+E+ ++++
Sbjct: 390 LEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQM 449
Query: 603 QELEGQIADLKKKLNE-QSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKF 661
+ + +A ++ + Q +L +L+ E ++ + ++ ++ V ++ +E +K
Sbjct: 450 LDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKT 509
Query: 662 RQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKD----- 716
R +Q D E+ Q Q EL +L Q+ SN +++ E N LKD
Sbjct: 510 RANEQLTD-ELAQKTTTLTTTQRELSQL----QELSNHQKKRATEIL--NLLLKDLGEIG 562
Query: 717 ---ALQKQREVAD-----KRKETQSR-GMEGTAARVKNWLGNEIEVMVSTEEAKRHLN-- 765
+ +AD + + T +R + + VK+ + ++ + ++ R +N
Sbjct: 563 GIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNAS 622
Query: 766 --DLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESL 823
+L + +++Q A++K + +N K R Q+ ES+DS+++++ L
Sbjct: 623 ERELAACQLLISQHEAKIKSLTDYMQNMEQKRR-----------QLEESQDSLSEELAKL 671
Query: 824 ETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLI-GELVSSKIQVS 882
Q+K+ + +D+ K+ + E K AL+ + + + Q+S
Sbjct: 672 RA------------QEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLS 719
Query: 883 KLESSLKQSKT---SCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQ 939
+L +++ + D+ + L E+ + +L+ E E + EK+L L + +
Sbjct: 720 RLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMK-LEKLLLLNDKRE 778
Query: 940 QSQMAEKQLEESVSEKEQQLLSTLKCQDEEL-EKMREVCEQNQQLLRENEIIKQKLTLLQ 998
Q++ K LEE+VS + Q L + K ++L ++++ E + + KQK++ L+
Sbjct: 779 QAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLE 838
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 283 bits (725), Expect = 5e-76
Identities = 210/604 (34%), Positives = 313/604 (51%), Gaps = 62/604 (10%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVV----GT----DKSFTYDFVFDPSTEQ 61
VRV +RCRP+ KE + + QV V GT K+FT+D V+D + +Q
Sbjct: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
Query: 62 EEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQL 121
E+++ PL+ V +G+N T+ AYGQTG+GKTY+M G ++ GVIP
Sbjct: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR----GVIPNSFDH 125
Query: 122 LFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTV 181
+F I + + ++ ++ SYLEIY EEI DLL + K ++ ++E P G+ + L+
Sbjct: 126 IFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTK-RLELKERPDTGVYVKDLSSFVT 184
Query: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKS-DKNSSFR-SKLHLV 239
+ + GN +R+V +T MN SSRSHAIF I++E + D + R KL+LV
Sbjct: 185 KSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLV 244
Query: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQD 299
DLAGSERQ KT A+G+RLKE IN L LGNVISAL D K +PYRDSKLTRLLQD
Sbjct: 245 DLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKST-HIPYRDSKLTRLLQD 303
Query: 300 SLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQ 359
SLGGN+ T+M+A V PA N+EETL TLRYA+RA+ IKNKP VN DP+ A L ++++
Sbjct: 304 SLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIA 363
Query: 360 QLQVLL------------LQAHGGTLPGSITVEPSENLQSLME---KNQSLVEENEKL-- 402
+L+ L + GG G E E + E K+ E+ EKL
Sbjct: 364 RLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEI 423
Query: 403 -SRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKE 461
R + E A+ R++ ++ K+E+LR+ L ++ +E + L
Sbjct: 424 EKRAIVEDHSLVAEEKMRLL------KEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVG 477
Query: 462 NVEII--CNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQ 519
I+ N QQ I + + +A EQ+ + + S D T +
Sbjct: 478 GKNIVDHTNEQQKILEQKRQEIA----------EQKRREREIQQQMESRDEETLELKETY 527
Query: 520 AQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELV 579
+ + +E+ + +K+ + S+LQ ++ + D +E E L++ + EL
Sbjct: 528 SSLQQEV----------DIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT 577
Query: 580 LELQ 583
EL+
Sbjct: 578 RELK 581
Score = 51.6 bits (122), Expect = 5e-06
Identities = 75/360 (20%), Positives = 153/360 (42%), Gaps = 34/360 (9%)
Query: 519 QAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEEL 578
Q + KE ++N +L+ + + S P Y+D+ L+ K +
Sbjct: 258 QGERLKEATKINLSLSALGNVISALVDGKSTHIP----YRDSKLTRLLQDSLGGNAKTVM 313
Query: 579 VLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQ 638
V + A + + + R R + ++ K ++NE K L+E E +++L
Sbjct: 314 VANVGPASYNVEETLTTLRYANRAKNIKN-----KPRVNEDPKDALLREFQEE-IARLKA 367
Query: 639 EIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSN 698
++ R + + +E ++++++ +E D K Y R Q++
Sbjct: 368 QLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYW-----REQQEKLE 422
Query: 699 VLRRKTEE--AAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVS 756
+ +R E + A ++++ +K++++ D R+E + M G A++K E +++V
Sbjct: 423 IEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLG--AKIK---AMESKLLVG 477
Query: 757 TEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRR---TFSLTEVRGQVSESE 813
+ H N E +KIL Q ++ E+K ++ R T L E + +
Sbjct: 478 GKNIVDHTN---EQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEV 534
Query: 814 DSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGE 873
D TK+++ L ++++ A+I DLQ E + +Q E L + LK+LI E
Sbjct: 535 DIKTKKLKKLFSKLQAVKAEIHDLQ------EEHIKERQELEQTQNELTRELKLKHLIIE 588
Score = 40.0 bits (92), Expect = 0.014
Identities = 54/262 (20%), Positives = 115/262 (43%), Gaps = 37/262 (14%)
Query: 675 LKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSR 734
+K + R + L R FQ++ L+ + E+ + ++ ++ ++ +E +
Sbjct: 340 IKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEE 399
Query: 735 GMEGTAARVKNWLGNEIEVMVSTEEAKRHLND--LLEDRKILAQDVAQL-KEKKESGENP 791
G EG G++ + ++ K + ++ED ++A++ +L KEK++ E+
Sbjct: 400 GEEGEEE------GDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMED- 452
Query: 792 PPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADL---QQKLLDAESED 848
LRR ++ + + +I+++E+++ I D QQK+L+ + ++
Sbjct: 453 ---LRRE-----------KDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQE 498
Query: 849 --RPKQRWENIATILEAKCALKYLIGELVSSKIQ--------VSKLESSLKQSKTSCADM 898
K+R I +E++ + E SS Q + KL S L+ K D+
Sbjct: 499 IAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDL 558
Query: 899 QKMLFEERNHFAEIETELQAEL 920
Q+ +ER + + EL EL
Sbjct: 559 QEEHIKERQELEQTQNELTREL 580
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 280 bits (715), Expect = 8e-75
Identities = 263/936 (28%), Positives = 439/936 (46%), Gaps = 123/936 (13%)
Query: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTE 60
M E ++V R RPL EI G + F G+ VV+G K + +D VF P+T
Sbjct: 1 MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIF-QGDDSVVIG-GKPYVFDRVFPPNTT 58
Query: 61 QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQ 120
QE+V++ ++K V GYN T+ AYGQT SGKT++M G Q +G+IPR+ +
Sbjct: 59 QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGIIPRIAR 114
Query: 121 LLFKEI-DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEK 179
+F I + EF +KVSY EIY ++I DLL + K +++ ED + G TE+
Sbjct: 115 DIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVT--KTNLSVHEDKNRVPFVKGCTER 172
Query: 180 TVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLV 239
V + + +++G ++R VA T MN SSRSH+IF I+++Q + + KL+LV
Sbjct: 173 FVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQ-ENMETEQKLSGKLYLV 231
Query: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQD 299
DLAGSE+ KT AEG L E NIN+ L LGNVISAL + K +VPYRDSK+TR+LQD
Sbjct: 232 DLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS-YVPYRDSKMTRILQD 290
Query: 300 SLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNID------PQTAELNH 353
SLGGN T M C SP+ N ET +TL + RA+ IKN VN++ + E
Sbjct: 291 SLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEK 350
Query: 354 LKQQVQQLQVLLLQAHGGTLPGSITVEPSENL-------------QSLMEKNQSLV---- 396
K + Q+ + L+A V +E L ++ + N S+V
Sbjct: 351 EKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIA 410
Query: 397 -EENEKLSRGL----------SEAAGQTAQMLER-----------IILTEQANEKMNAKL 434
EE +K + + Q +Q++E+ ++ T NEK+ +L
Sbjct: 411 PEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL 470
Query: 435 EELR-QHAACKLDLQKLVETLE------DQELKENVEIICNLQQLITQLSDETVACMAAA 487
L+ ++ A K +++++++ LE DQ+ +E E Q L+ +LS +
Sbjct: 471 SHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQK-------- 522
Query: 488 IDTAVEQEAQVETSPETS---RSSDAFTTQHALRQAQMSKELV---ELNKALALKEALAR 541
+ T + E++++ E S R A ++ +V E+ + + A+
Sbjct: 523 VATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEE 582
Query: 542 KMTQNDSQLQPIQYQYQDNIK---ELELEVINLQKEKEELVLELQTAKK--DANQAKLS- 595
+ T + I+ + + +K +LE + ++ E EL + + ++AK+
Sbjct: 583 EFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRS 642
Query: 596 --------ERRRKRLQELEGQIADLKKKLNEQSKL----LKLKESTERTVSKLNQEIRM- 642
E +++ L+E ++D KL Q + LK KE + ++ + + +
Sbjct: 643 LTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQ 702
Query: 643 MKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRR 702
M++ R RQ+ + R +K K + +LK+ ++K Q EL KL+ +++K
Sbjct: 703 MESHREAHHRQL----ARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEK------L 752
Query: 703 KTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVS--TEEA 760
K+EE + K + +R K+ +G+E T AR L N ++ V T
Sbjct: 753 KSEEHEKSTKLQELTFLYERHEQSKQ---DLKGLEETVARELQTLHNLRKLFVQDVTTRV 809
Query: 761 KRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQI 820
K+ ED + + K+K EN LT+V Q+ + ++
Sbjct: 810 KKSAEMEPED----SGGIHSQKQKISFLEN-------NLEQLTKVHKQLVRDNADLRCEL 858
Query: 821 ESLETEMEFRSAQIADLQQKLLDA-ESEDRPKQRWE 855
LE + + ++ L+ L +A E + K+R++
Sbjct: 859 PKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQ 894
Score = 50.8 bits (120), Expect = 8e-06
Identities = 95/463 (20%), Positives = 193/463 (41%), Gaps = 82/463 (17%)
Query: 663 QWKQKKDKEVIQLKERDRKRQYELLKLE------RNFQKQSNVLRRKTEEAAAANKRLKD 716
QWK+K +KE KE+ + ++ + KLE RN + R EEAA + ++
Sbjct: 341 QWKKKYEKE----KEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEE 396
Query: 717 A--------------------------LQKQREVADKRKETQSRGMEGTAARVKNWLGNE 750
L KQ + D QS+ +E ++K + ++
Sbjct: 397 TPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIE----KLKQQMLDQ 452
Query: 751 IEVMVST----EEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVR 806
E++VST E+ +R L+ L + +V KE ++ E +++ + E
Sbjct: 453 EELLVSTRGDNEKVQRELSHLQSENDAAKDEV---KEVLQALEELAVNYDQKSQEVEEKS 509
Query: 807 GQVSESEDSITKQIE---SLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEA 863
Q D +++++ SLE+E++ R +++ Q+K + K E +
Sbjct: 510 QQNQLLVDELSQKVATMLSLESELQ-RLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNG 568
Query: 864 KCALKYLIG-----ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQA 918
+ L I E +++ +SK++S +K C ++ + E EL +
Sbjct: 569 EIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSS 628
Query: 919 ELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCE 978
+ + Q H+ K+ L +Q ++ ++ LEES + L+ L+ Q E + EV
Sbjct: 629 CQLLISQ-HEAKIRSLTEYMQSVELKKRHLEESYDSLSDE-LAKLQAQ----ETVHEVAL 682
Query: 979 QNQQL-LRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQ 1037
++++ ++ + +K+ L L + R+ H + +R++++ E+
Sbjct: 683 KDKEPDTQDADEVKKALELQMESHREAH------------------HRQLARLRDEINEK 724
Query: 1038 SMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEW-KPTKLVKVS 1079
I++LK ++ E E D ++ EE K TKL +++
Sbjct: 725 QKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELT 767
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 279 bits (713), Expect = 1e-74
Identities = 235/769 (30%), Positives = 357/769 (46%), Gaps = 78/769 (10%)
Query: 44 GTDKSFTYDFVF---DPSTE-----QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKT 95
G K F YD F D S + Q+ VF +++ F GYNA + AYGQTGSGK+
Sbjct: 51 GQPKVFAYDHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKS 110
Query: 96 YSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLC 153
Y+M G TA+Q G+IPR+ LF+ K+ + E F ++VSY+EIYNE++ DLL
Sbjct: 111 YTMMG--TADQP-----GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLD 163
Query: 154 PSREKAQINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSH 213
P + + +RE G + GL++ V D S + +GN SRTVA+T MN +SSRSH
Sbjct: 164 PKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSH 223
Query: 214 AIFTISLEQRK---KSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCL 270
A+F I+L KS + KL LVDLAGSER KT A GDRLKEG NIN+ L L
Sbjct: 224 AVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTL 283
Query: 271 GNVISALGDDKKGG----FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNT 326
G VISAL D G FVPYRDS LT LL+DSLGGNS T M+A VSPA N +ETL+T
Sbjct: 284 GLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLST 343
Query: 327 LRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQ 386
LRYADRA+ I N +VN DP + L+++V++L+ L +A P L+
Sbjct: 344 LRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSP---------ELK 394
Query: 387 SLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEEL---RQHAAC 443
+E+++ L++E T E++ TE+ ++ +LE L Q +
Sbjct: 395 DRLEESEKLIQE-------------MTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGI 441
Query: 444 KLDLQK--LVETLEDQELKENVEIICNLQQLITQLSDETVACMA-------AAIDTAVEQ 494
K+ K LV D L E + LI + + + ID E
Sbjct: 442 KVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEG 501
Query: 495 EAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQ 554
+ + T + + ++ + L N L +K + + + Q
Sbjct: 502 QVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPS 561
Query: 555 YQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKL--SERRRKRLQELEGQIADL 612
+ +++ ++L+++ + + E+ + A+ + L ++ + L LE Q +
Sbjct: 562 MKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEE 621
Query: 613 KKKLNEQSKLL--KLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDK 670
K+ E+ +L+ E R +S Q R M + ++ RQW +
Sbjct: 622 KRSALERQRLMYEHELEQLRRRLSPEKQNCRSMD----RFSFHSPSAQQRLRQWAE---- 673
Query: 671 EVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKR--LKDALQKQREVADKR 728
ER+ L++L K + ++R A +KR K LQ D
Sbjct: 674 ------EREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIPASSLDAN 727
Query: 729 KETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQD 777
++ S E + G +I + + + DL ++ K +D
Sbjct: 728 RKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEED 776
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 276 bits (707), Expect = 7e-74
Identities = 183/476 (38%), Positives = 276/476 (57%), Gaps = 42/476 (8%)
Query: 5 VKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVG------TDKSFTYDFVF--- 55
+ G V+VA+R RP +E S+ + C+ + G ++ KSF++D+ +
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESK-CIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSH 59
Query: 56 ----DPS-TEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEP 110
DP Q V+N ++ F+GYN + AYGQTG+GK+Y+M G ++ E
Sbjct: 60 TSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMG-----KQEES 114
Query: 111 TVGVIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLCPSREKAQINIREDPK 168
G+IP++ + LF++I+ + E ++++VSY+EIY E + DLL P + K + +RE P
Sbjct: 115 QAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNP-KNKGNLRVREHPL 173
Query: 169 EGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDK 228
G + L++ V D ++ GN +RTVA+T MN SSRSHA+FTI Q+K ++
Sbjct: 174 LGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNE 233
Query: 229 NSSFR---SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD----DK 281
+ SK+ LVDLAGSER T A+G RLKEG NIN+ L LG VISAL + K
Sbjct: 234 TNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKK 293
Query: 282 KGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPI 341
K F+PYRDS LT LL+++LGGNS T M+A +SPAD N +ETL+TLRYADRA++IK +
Sbjct: 294 KTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAV 353
Query: 342 VNIDPQTAELNHLKQQVQQLQVLLLQAHG-----GTLPGSITVEPSENLQSLMEKNQSLV 396
+N DP + LK++V +L+ LL+A G T GS+T PS S S+
Sbjct: 354 INEDPNAKLVRELKEEVTRLKD-LLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVT 412
Query: 397 EENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEE-LRQHAACKLDLQKLV 451
E++ +S G+ A +ER+ +E+ ++N EE LR+ A +++ + L+
Sbjct: 413 SIQERI---MSTPGGEEA--IERLKESEKIIAELNETWEEKLRKTEAIRMEREALL 463
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 276 bits (707), Expect = 7e-74
Identities = 183/476 (38%), Positives = 276/476 (57%), Gaps = 42/476 (8%)
Query: 5 VKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVG------TDKSFTYDFVF--- 55
+ G V+VA+R RP +E S+ + C+ + G ++ KSF++D+ +
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESK-CIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSH 59
Query: 56 ----DPS-TEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEP 110
DP Q V+N ++ F+GYN + AYGQTG+GK+Y+M G ++ E
Sbjct: 60 TSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMG-----KQEES 114
Query: 111 TVGVIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLCPSREKAQINIREDPK 168
G+IP++ + LF++I+ + E ++++VSY+EIY E + DLL P + K + +RE P
Sbjct: 115 QAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNP-KNKGNLRVREHPL 173
Query: 169 EGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDK 228
G + L++ V D ++ GN +RTVA+T MN SSRSHA+FTI Q+K ++
Sbjct: 174 LGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNE 233
Query: 229 NSSFR---SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD----DK 281
+ SK+ LVDLAGSER T A+G RLKEG NIN+ L LG VISAL + K
Sbjct: 234 TNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKK 293
Query: 282 KGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPI 341
K F+PYRDS LT LL+++LGGNS T M+A +SPAD N +ETL+TLRYADRA++IK +
Sbjct: 294 KTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAV 353
Query: 342 VNIDPQTAELNHLKQQVQQLQVLLLQAHG-----GTLPGSITVEPSENLQSLMEKNQSLV 396
+N DP + LK++V +L+ LL+A G T GS+T PS S S+
Sbjct: 354 INEDPNAKLVRELKEEVTRLKD-LLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVT 412
Query: 397 EENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEE-LRQHAACKLDLQKLV 451
E++ +S G+ A +ER+ +E+ ++N EE LR+ A +++ + L+
Sbjct: 413 SIQERI---MSTPGGEEA--IERLKESEKIIAELNETWEEKLRKTEAIRMEREALL 463
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 271 bits (693), Expect = 3e-72
Identities = 188/455 (41%), Positives = 254/455 (55%), Gaps = 56/455 (12%)
Query: 10 VRVALRCRPLVPKEIS---------EGCQMCLSFVPGEP-QVVVGTDKSFTYDFVFDPST 59
V+VA+R RP+ +E+ EG Q L P Q K F +D+ F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65
Query: 60 E--------QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
E QE VF +++ F+GYNA + AYGQTGSGK++SM G AEQ
Sbjct: 66 ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AEQ----- 118
Query: 112 VGVIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
+G+IPR+ LFK I ++ F ++VSY+EIYNE++ DLL P + + +RE
Sbjct: 119 LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK---KS 226
G + GL++ V D S + +GN SRTVA+T MN +SSRSHA+F I + Q +S
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 227 DKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGG-- 284
+ SK+ LVDLAGSER KT A G+RLKEG NIN+ L LG VIS+L D G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 285 --FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIV 342
FVPYRDS LT LL+D+LGGNS T MIA +SPA N EETL+TLRYADRA++I N +V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 343 NIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKL 402
N DP + L+++V++L+ L QA P L EK +EE+EKL
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAP------------ELKEK----LEESEKL 402
Query: 403 SRGLSEAAGQTAQMLERIILTEQANEKMNAKLEEL 437
+ L T E++ TE+ ++ +LE +
Sbjct: 403 IKEL------TVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 271 bits (693), Expect = 3e-72
Identities = 188/455 (41%), Positives = 254/455 (55%), Gaps = 56/455 (12%)
Query: 10 VRVALRCRPLVPKEIS---------EGCQMCLSFVPGEP-QVVVGTDKSFTYDFVFDPST 59
V+VA+R RP+ +E+ EG Q L P Q K F +D+ F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65
Query: 60 E--------QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
E QE VF +++ F+GYNA + AYGQTGSGK++SM G AEQ
Sbjct: 66 ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AEQ----- 118
Query: 112 VGVIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
+G+IPR+ LFK I ++ F ++VSY+EIYNE++ DLL P + + +RE
Sbjct: 119 LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK---KS 226
G + GL++ V D S + +GN SRTVA+T MN +SSRSHA+F I + Q +S
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 227 DKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGG-- 284
+ SK+ LVDLAGSER KT A G+RLKEG NIN+ L LG VIS+L D G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 285 --FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIV 342
FVPYRDS LT LL+D+LGGNS T MIA +SPA N EETL+TLRYADRA++I N +V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 343 NIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKL 402
N DP + L+++V++L+ L QA P L EK +EE+EKL
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAP------------ELKEK----LEESEKL 402
Query: 403 SRGLSEAAGQTAQMLERIILTEQANEKMNAKLEEL 437
+ L T E++ TE+ ++ +LE +
Sbjct: 403 IKEL------TVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 271 bits (693), Expect = 3e-72
Identities = 188/455 (41%), Positives = 254/455 (55%), Gaps = 56/455 (12%)
Query: 10 VRVALRCRPLVPKEIS---------EGCQMCLSFVPGEP-QVVVGTDKSFTYDFVFDPST 59
V+VA+R RP+ +E+ EG Q L P Q K F +D+ F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65
Query: 60 E--------QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
E QE VF +++ F+GYNA + AYGQTGSGK++SM G AEQ
Sbjct: 66 ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AEQ----- 118
Query: 112 VGVIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
+G+IPR+ LFK I ++ F ++VSY+EIYNE++ DLL P + + +RE
Sbjct: 119 LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK---KS 226
G + GL++ V D S + +GN SRTVA+T MN +SSRSHA+F I + Q +S
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 227 DKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGG-- 284
+ SK+ LVDLAGSER KT A G+RLKEG NIN+ L LG VIS+L D G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 285 --FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIV 342
FVPYRDS LT LL+D+LGGNS T MIA +SPA N EETL+TLRYADRA++I N +V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 343 NIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKL 402
N DP + L+++V++L+ L QA P L EK +EE+EKL
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAP------------ELKEK----LEESEKL 402
Query: 403 SRGLSEAAGQTAQMLERIILTEQANEKMNAKLEEL 437
+ L T E++ TE+ ++ +LE +
Sbjct: 403 IKEL------TVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 271 bits (693), Expect = 3e-72
Identities = 188/455 (41%), Positives = 254/455 (55%), Gaps = 56/455 (12%)
Query: 10 VRVALRCRPLVPKEIS---------EGCQMCLSFVPGEP-QVVVGTDKSFTYDFVFDPST 59
V+VA+R RP+ +E+ EG Q L P Q K F +D+ F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65
Query: 60 E--------QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
E QE VF +++ F+GYNA + AYGQTGSGK++SM G AEQ
Sbjct: 66 ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AEQ----- 118
Query: 112 VGVIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
+G+IPR+ LFK I ++ F ++VSY+EIYNE++ DLL P + + +RE
Sbjct: 119 LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK---KS 226
G + GL++ V D S + +GN SRTVA+T MN +SSRSHA+F I + Q +S
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 227 DKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGG-- 284
+ SK+ LVDLAGSER KT A G+RLKEG NIN+ L LG VIS+L D G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 285 --FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIV 342
FVPYRDS LT LL+D+LGGNS T MIA +SPA N EETL+TLRYADRA++I N +V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 343 NIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKL 402
N DP + L+++V++L+ L QA P L EK +EE+EKL
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAP------------ELKEK----LEESEKL 402
Query: 403 SRGLSEAAGQTAQMLERIILTEQANEKMNAKLEEL 437
+ L T E++ TE+ ++ +LE +
Sbjct: 403 IKEL------TVTWEEKLRKTEEIAQERQRQLESM 431
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 269 bits (687), Expect = 1e-71
Identities = 269/1016 (26%), Positives = 471/1016 (46%), Gaps = 100/1016 (9%)
Query: 2 KEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTD--------KSFTYDF 53
K+E KG ++V +RCRP E + P +V V T K++T+D
Sbjct: 11 KKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDM 70
Query: 54 VFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQE----NE 109
VF ST+Q +V+ + V P++ V GYN T+ AYGQTG+GKT++M G + +E +
Sbjct: 71 VFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEED 130
Query: 110 PTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQ-INIREDP- 167
P G+IPR + +F+++ EF++KVS LEIYNEE+ DLL PS + ++ + + +DP
Sbjct: 131 PLAGIIPRTLHQIFEKLTDNGT-EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPR 189
Query: 168 -KEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKS 226
K G+ I GL E TV + LE+G RT A+T MN+ SSRSH++F++++ ++ +
Sbjct: 190 NKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETT 249
Query: 227 DKNSSFRS--KLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGG 284
KL+LVDLAGSE ++ A R +E NIN+ LL LG VI+AL + +
Sbjct: 250 IDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE--RTP 307
Query: 285 FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVN- 343
VPYR+SKLTR+LQDSLGG + T +IA +SPA NLEETL+TL YA RA+ I NKP VN
Sbjct: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQ 367
Query: 344 -------IDPQTAELNHLKQQV----QQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKN 392
I T E+ LK+ + ++ V + + + + G +TV+ E + L+EK
Sbjct: 368 KLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQ-EEQIVELIEKI 426
Query: 393 QSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVE 452
++ EE +++ + + Q + Q E L+E + + + +E
Sbjct: 427 GAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALE 486
Query: 453 TLEDQELKENVEIICNLQQLITQLSDETVACMAAAID--TAVEQEAQVETSPETSRSSDA 510
+ E ++L + + N + T + V+ + + +D AV+Q +
Sbjct: 487 STE-EKLHDAASKLLNTVEETT----KDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSL 541
Query: 511 FTTQHALRQAQMSKE--LVELNKAL---ALKEALARKMTQNDSQLQPIQYQYQDNIKELE 565
F L + SK+ ++E++K L L +++ T L + +N+
Sbjct: 542 FNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLT-SIPENVSTHV 600
Query: 566 LEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKL 625
++ N+ +++ L E +T ++ ++ L + + K ++ + K
Sbjct: 601 SQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKT 660
Query: 626 KESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQ-LKERDRKRQY 684
+ + +E+ + + +++E+ QK+ + + LK +
Sbjct: 661 SLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQ 720
Query: 685 ELLKLERNFQKQSNVLRRKTEEAAAANKRLKDAL-QKQREVADK---RKETQSRGMEGTA 740
EL KL + ++ L K E +++ + QK +++ +K + +G +
Sbjct: 721 ELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS 780
Query: 741 ARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTF 800
++N+ +++ EE+ +H + L + + ++Q+ Q E L RT
Sbjct: 781 QELRNFNQEGTKLV---EESVKHSDKLNGNLEKISQETEQRCE----------SLNTRTV 827
Query: 801 SLTEV-RGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQR--WENI 857
+E ++E E + +E + E S+ I + D KQ + +
Sbjct: 828 YFSEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKS----DGRKAAHEKQHNIFLDQ 883
Query: 858 ATILEAKCALKYL-IGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETEL 916
TI E K + L + E + KI ++KL L+Q D+ +R + T
Sbjct: 884 MTIDEDKLIAQNLELNETI--KIGLTKLNCFLEQDLK--LDIPTGTTPQRKSYLYPST-- 937
Query: 917 QAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEK 972
LVR E + +LL QL++ K+ +LL L C + E+
Sbjct: 938 ---LVRTEPRE-----HLLDQLKR--------------KQPELLMMLNCSENNKEE 971
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 269 bits (687), Expect = 1e-71
Identities = 174/479 (36%), Positives = 273/479 (56%), Gaps = 46/479 (9%)
Query: 7 GIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVG------TDKSFTYDFVFDPSTE 60
G V+VA+R RP +E+S + C+ + G +V T KSF++D+ + T
Sbjct: 3 GASVKVAVRVRPFNSREMSRDSK-CIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTS 61
Query: 61 --------QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112
Q++V+ +++ F+GYN + AYGQTG+GK+Y+M G +Q+
Sbjct: 62 PEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQ----- 116
Query: 113 GVIPRVIQLLFKEIDKKSD--FEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEG 170
G+IP++ + LF I+ ++ ++++VSY+EIY E + DLL P + K + +RE P G
Sbjct: 117 GIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNP-KNKGNLRVREHPLLG 175
Query: 171 IKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK---KSD 227
+ L++ V D ++ GN +RTVA+T MN SSRSHA+F I Q++ +++
Sbjct: 176 PYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETN 235
Query: 228 KNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-------- 279
+ SK+ LVDLAGSER T A+G RLKEG NIN+ L LG VISAL +
Sbjct: 236 ITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKN 295
Query: 280 --DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIK 337
KK F+PYRDS LT LL+++LGGNS T M+A +SPAD N +ETL+TLRYADRA++I+
Sbjct: 296 KKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIR 355
Query: 338 NKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLP----GSITVEPSENLQSLMEKNQ 393
++N DP + LK +V +L+ LL G + + + PS +L +L +
Sbjct: 356 CNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDMTNALVGMSPSSSLSALSSRAA 415
Query: 394 SLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEE-LRQHAACKLDLQKLV 451
S+ +E++ A + + +ER+ TE+ ++N EE LR+ A +++ + L+
Sbjct: 416 SVSSLHERIL-----FAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALL 469
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 266 bits (681), Expect = 7e-71
Identities = 215/704 (30%), Positives = 349/704 (49%), Gaps = 102/704 (14%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTD--------KSFTYDFVFDPSTEQ 61
++V RCRPL KE + G + L+ QV + K+FT+D V+D S++Q
Sbjct: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
Query: 62 EEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV-GVIPRVIQ 120
++++ V PLI V +G+N TV AYGQTG+GKTY+M G + EP + GVIP +
Sbjct: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWV-----EPELRGVIPNAFE 125
Query: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
+F I + + ++ ++ SYLEIY EEI DLL K ++ ++E+P+ G+ I L+
Sbjct: 126 HIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGK-RLELKENPETGVYIKDLSSFV 184
Query: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLE-QRKKSDKNSSFR-SKLHL 238
+ + GN +R V ST MN SSRSHAIF I++E + SD R KL+L
Sbjct: 185 TKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNL 244
Query: 239 VDLAGSERQKKTK------------------------AEGDRLKEGININRGLLCLGNVI 274
VDLAGSERQ K A G+R KE IN L LGNVI
Sbjct: 245 VDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVI 304
Query: 275 SALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRAR 334
+AL ++ +PYRDSKLTRLLQDSLGGN+ T+M+A + PA + +E+L+TLR+A+RA+
Sbjct: 305 AALAGNRST-HIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAK 363
Query: 335 KIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQS 394
IKNKP VN DP+ L ++++ +L+ L + G + P
Sbjct: 364 NIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKR------GMLGKRPR------------ 405
Query: 395 LVEENEKLSRGLSEAAG-QTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVET 453
++ + + +S G ++E + E+ + N + + +A + +++ ++
Sbjct: 406 --RKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQE 463
Query: 454 LEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTT 513
+ + L+E I + + L+++ + + E+E +E + R A
Sbjct: 464 -QKERLEEEKAAIQDDRSLVSEEKQKLLE----------EKEKMLE---DLRREQQATEL 509
Query: 514 QHALRQAQMSKELV----------ELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKE 563
A +A SK L+ E K L LK + + + ++Q + E
Sbjct: 510 LAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETME 569
Query: 564 LELEVINLQKEKEELVLELQT--AKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSK 621
L +LQ+E E +L+ AK A +A++ ++ + ++ + DL++ NEQ++
Sbjct: 570 LRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQ----DLEEAQNEQTR 625
Query: 622 LLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWK 665
LKLK L E + ++ ++M ++ D E+ QWK
Sbjct: 626 ELKLK--------YLIIENFIPPEEKNKIMNRLFLDCEE-EQWK 660
Score = 41.6 bits (96), Expect = 0.005
Identities = 36/171 (21%), Positives = 83/171 (48%), Gaps = 19/171 (11%)
Query: 564 LELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLL 623
LE + N +E++E + E + A +D +++ +SE ++K L+E E + DL+++
Sbjct: 453 LEKNMENYLQEQKERLEEEKAAIQD-DRSLVSEEKQKLLEEKEKMLEDLRRE-------- 503
Query: 624 KLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQ 683
+++TE +K + M+++ + R + + + ++ + K +E+ + K R+R+ Q
Sbjct: 504 --QQATELLAAK----YKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQ 557
Query: 684 YELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK----QREVADKRKE 730
E++ + + +E K+LK K + E+ D+ E
Sbjct: 558 QEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDE 608
Score = 37.7 bits (86), Expect = 0.068
Identities = 67/296 (22%), Positives = 118/296 (39%), Gaps = 53/296 (17%)
Query: 692 NFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEI 751
N + +LR EE A RLK L+K+ + + + SR + +A G I
Sbjct: 372 NEDPKDTLLREFQEEIA----RLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVI 427
Query: 752 EVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSE 811
E V+ EE + + PP +
Sbjct: 428 EAWVAEEE-----------------------DDNNNNHRPPQPILESALE--------KN 456
Query: 812 SEDSITKQIESLETE---MEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALK 868
E+ + +Q E LE E ++ + +++ +QKLL+ + + R E AT L A K
Sbjct: 457 MENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATEL---LAAK 513
Query: 869 YLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAE---IETELQAELVRMEQ 925
Y K SKL + + QKML +R AE E E+Q E++ ++
Sbjct: 514 Y--------KAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDE 565
Query: 926 QHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQ 981
+ E S Q+ ++ K+L++ + K Q + + ++ Q +E ++R+ E+ Q
Sbjct: 566 ETMELRGTYTSLQQEVEVKTKKLKK-LYAKLQAVKAEIQDQHDEYIRVRQDLEEAQ 620
Score = 33.9 bits (76), Expect = 0.98
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 2/108 (1%)
Query: 888 LKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQ 947
L++ K + D + ++ EE+ E E E E +R EQQ E +L + +S++
Sbjct: 468 LEEEKAAIQDDRSLVSEEKQKLLE-EKEKMLEDLRREQQATE-LLAAKYKAMESKLLIGG 525
Query: 948 LEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLT 995
EQQ + LK Q+ +K RE Q + +LR+ E ++ + T
Sbjct: 526 RNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGT 573
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 261 bits (667), Expect = 3e-69
Identities = 175/484 (36%), Positives = 269/484 (55%), Gaps = 49/484 (10%)
Query: 7 GIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVG------TDKSFTYDFVF----- 55
G V+VA+R RP +E S+ + C+ + G ++ KSFT+D+ +
Sbjct: 3 GASVKVAVRVRPFNARETSQDAK-CVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTS 61
Query: 56 --DPS-TEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112
DP Q++V+ ++ F+GYN + AYGQTG+GK+Y+M G Q+
Sbjct: 62 TEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQ----- 116
Query: 113 GVIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEG 170
G++P++ + LF + ++ + ++++VSY+EIY E + DLL P + + + +RE P G
Sbjct: 117 GIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNP-KSRGSLRVREHPILG 175
Query: 171 IKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQR---KKSD 227
+ L++ V D ++ GN +RTVA+T MN SSRSHA+FTI QR + +
Sbjct: 176 PYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTG 235
Query: 228 KNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD----DKKG 283
+S SK+ LVDLAGSER + A G RLKEG NIN+ L LG VISAL D +K
Sbjct: 236 LDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKS 295
Query: 284 GFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVN 343
F+PYRDS LT LL+++LGGNS T MIA +SPAD N EETL+TLRYADR ++I+ I+N
Sbjct: 296 DFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIIN 355
Query: 344 IDPQTAELNHLKQQVQQLQVLL------------LQAHGGTLPGSITVEPSENLQSLMEK 391
DP + L+++V +L+ LL L+ G++ G++ P+ +
Sbjct: 356 EDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGAL---PAVSSPPAPVS 412
Query: 392 NQSLVEENEKLSRGLS---EAAGQTAQMLERIILTEQANEKMNAKLEE-LRQHAACKLDL 447
S N +L S E+ + +ER+ TE+ ++N EE LR+ A +++
Sbjct: 413 PSSPTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMER 472
Query: 448 QKLV 451
+ L+
Sbjct: 473 EALL 476
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 260 bits (664), Expect = 6e-69
Identities = 226/811 (27%), Positives = 380/811 (46%), Gaps = 103/811 (12%)
Query: 4 EVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPS----- 58
+V+ V VA+R RP +E E + F+ G+ V D Y+F++D S
Sbjct: 353 KVENSQVTVAVRVRPFTKREKIEKASQVV-FMSGKEITVEHPDTKQVYNFIYDVSFWSFD 411
Query: 59 ------TEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112
Q V+ APL++ F+G+N + AYGQTGSGK+Y+M G EP
Sbjct: 412 ECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGF-----SEEP-- 464
Query: 113 GVIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLCPSREKAQ----INIRED 166
G+IPR + LF ++ +K E + +++S+ E+YNE+I DLL E Q + +RE
Sbjct: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREH 524
Query: 167 PKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKS 226
P G + L+ V D S LE GN R A+T MN +SSRSH++FT+ + Q K
Sbjct: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
Query: 227 -----DKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-- 279
+ + S+++L+DLAGSER GDRLKEG++IN+ LL LG VISAL +
Sbjct: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
Query: 280 DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNK 339
+++ F+PYR+S LT LL++SLGGNS T MIA +SPA SN+EETL+TLRYA++AR I N
Sbjct: 645 NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNI 704
Query: 340 PIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEEN 399
VN D + LK ++ +L+ S ++P E + ++ SL +
Sbjct: 705 AKVNEDMNAKLIRELKAEIAKLK--------AAQRNSRNIDP-ERYRLCRQEITSLRMKL 755
Query: 400 EKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAAC-KLD--LQKLVETLED 456
+ R ++E + EQA ++ + +EL++ ++D L LV ED
Sbjct: 756 HQQERDMAEMQRVWKEKF------EQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNED 809
Query: 457 QELKENVEIIC----------------NLQQLITQLSDETVACMAAAIDTAVEQEAQVET 500
+L E + + ++Q ++D+ ++ + +T
Sbjct: 810 PQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKT 869
Query: 501 SPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDN 560
+ +H R N + +++ P +++ N
Sbjct: 870 YVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKN 929
Query: 561 ------IKELELEVINLQ-KEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLK 613
+LE E+ Q K KEE++ +Q AK+ A Q S++ E +I L+
Sbjct: 930 ELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQK-----AAYESKIKALE 984
Query: 614 KKLNEQSKLLKLK-----------ESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFR 662
+L E+S+ K++ E E+ L QEI + K +R+++ + A +
Sbjct: 985 AELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNK-KRLEMETLATKQALEDH 1043
Query: 663 QWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQR 722
+ + E ++ +++ ++ ++L+ RN N + T + ++ +L +Q+
Sbjct: 1044 SIRHARILEALETEKQKIAKEVQILQQNRN-----NRDKTFTVQTTWSSMKLSMMIQEAN 1098
Query: 723 EVADK--------RKETQSRGMEGTAARVKN 745
++ K R + + T+ RV+N
Sbjct: 1099 AISSKLKTYYVFGRHDISDKSSSDTSIRVRN 1129
Score = 52.4 bits (124), Expect = 3e-06
Identities = 101/495 (20%), Positives = 210/495 (42%), Gaps = 80/495 (16%)
Query: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQ 583
KE V +NK+L + +++ +Q + + Y++++ L+ K ++ +
Sbjct: 621 KEGVSINKSLLTLGKVISALSEQANQ-RSVFIPYRESVLTWLLKESLGGNSKTAMIATIS 679
Query: 584 TAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQ------SKLLKLKESTERTVSKLN 637
A + + LS R L IA + + +N + +++ KLK + + +
Sbjct: 680 PAASNIEET-LSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDP 738
Query: 638 QEIRMMKNQ----RVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNF 693
+ R+ + + R++L +Q ++ AE R WK+K + Q ++R + EL K F
Sbjct: 739 ERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFE----QAEKRKLQETKELQKAGIMF 794
Query: 694 QKQSNVLRR-KTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTA-------ARVKN 745
Q +++ E ++ L +++ K K S ++ + +KN
Sbjct: 795 QMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKN 854
Query: 746 WLGNEIEVMVSTEEAKRHLN--DLLE-------DRKILAQD--------VAQLKEKKESG 788
+ G + + + EAK ++N +LE DR IL D V K K+ SG
Sbjct: 855 F-GGTVSI-IPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSG 912
Query: 789 ENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAE-SE 847
+ P +SE + EF ++ Q+ L+AE E
Sbjct: 913 RDTP----------------ISEG-----------PKDFEFAKNELLMAQRSQLEAEIKE 945
Query: 848 DRPKQRWENIATILEAK-CALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEER 906
+ K + E + I AK A + L + + + ++ LE+ L++ ++ MQ++ ++
Sbjct: 946 AQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELRE-ESQRKKMQEINNQKA 1004
Query: 907 NHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQ 966
NH E EL + +Q ++++ +L+ +A KQ E S + ++L L+ +
Sbjct: 1005 NHKIE-------ELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETE 1057
Query: 967 DEELEKMREVCEQNQ 981
+++ K ++ +QN+
Sbjct: 1058 KQKIAKEVQILQQNR 1072
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 258 bits (660), Expect = 2e-68
Identities = 190/519 (36%), Positives = 273/519 (52%), Gaps = 62/519 (11%)
Query: 12 VALRCRPLVPKEISEGCQMCLSFVPGEPQVVV--------------GTDKSFTYDFVFDP 57
VALR RP+ E+ EG + V + V++ +KS+ +D FD
Sbjct: 14 VALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDF 73
Query: 58 STEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPR 117
+ QE V+ LI+GV GYNATV AYG TG GKTY+M G + EP G+ +
Sbjct: 74 TATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGT-----DQEP--GIYVQ 126
Query: 118 VIQLLFKEIDKKS-DFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGL 176
+ LF+ I++ S D E+ + +SYLEIYNE I DLL PS + +RED K I++ G+
Sbjct: 127 TLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSL--GYLELREDSKGVIQVAGI 184
Query: 177 TEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK--KSDKNSSFRS 234
TE + + A + + L +GN RT TA N SSRSHA+ +++ QR K+ +
Sbjct: 185 TEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQG 244
Query: 235 KLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLT 294
+L ++DLAGSER +T+ G R+KEG +INR LL LGN I+AL D ++ YRDSKLT
Sbjct: 245 RLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLT 304
Query: 295 RLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNK---PIVNIDPQTA-- 349
RLL+DSLGGNS T+MIA +SPA S EE+ NTL YA RA+ IK + ++N+ A
Sbjct: 305 RLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYHIAQY 364
Query: 350 ---------ELNHLKQQVQQLQVLLLQAHGGTLPGSIT-VEPSENLQSLMEKNQSLVEEN 399
E+ LK+++ + Q QA G G I ++ L S + + +
Sbjct: 365 TSIIADLRGEIQRLKRKIDE-QTGRGQARGRQDRGDIRHIQAEVQLHSGQGEKAGMGQLR 423
Query: 400 EKLSRGLSEAAGQTAQMLE-------------RIILTEQA--NEKMNAKL---EELRQHA 441
E+L+ E ++LE R +LT +EK L EE R+
Sbjct: 424 EQLASAFQEQMDVRRRLLELENRAMEVQIDTSRHLLTIAGWKHEKSRRALKWREEQRKEC 483
Query: 442 ACKLDLQKLVETLEDQ-ELKENVEIICNLQQLITQLSDE 479
K D +K +T +DQ ++ E E+ ++ I L DE
Sbjct: 484 YAKDDSEKDSDTGDDQPDILEPPEVAA-ARESIAALVDE 521
Score = 36.6 bits (83), Expect = 0.15
Identities = 76/454 (16%), Positives = 166/454 (36%), Gaps = 76/454 (16%)
Query: 378 TVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERII-LTEQANEKMNAKLEE 436
T+ E +Q LM+ N+ +E AA QT+ ++ +T + ++ L+E
Sbjct: 189 TINAKEIMQLLMKGNRQRTQE--------PTAANQTSSRSHAVLQVTVRQRSRVKNILQE 240
Query: 437 LRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEA 496
+RQ +DL + Q + ++ ++ + + L + C+ A D +
Sbjct: 241 VRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGN----CINALSDKGSNKYI 296
Query: 497 QVETSPETSRSSDAF----TTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQP 552
S T D+ T + S E L T+ L
Sbjct: 297 NYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLN 356
Query: 553 IQY---QYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQI 609
+ Y QY I +L E+ L+++ +E QT + A + R ++ ++ ++
Sbjct: 357 VSYHIAQYTSIIADLRGEIQRLKRKIDE-----QTGRGQAR----GRQDRGDIRHIQAEV 407
Query: 610 ADLKKKLNEQSKLLKLKESTERTVSK---LNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQ 666
L E++ + +L+E + + + + ++N+ +++ WK
Sbjct: 408 -QLHSGQGEKAGMGQLREQLASAFQEQMDVRRRLLELENRAMEVQIDTSRHLLTIAGWKH 466
Query: 667 KKDKEVIQLKERDRKRQYE--------------------------------LLKLERNFQ 694
+K + ++ +E RK Y L+ ++ +
Sbjct: 467 EKSRRALKWREEQRKECYAKDDSEKDSDTGDDQPDILEPPEVAAARESIAALVDEQKQLR 526
Query: 695 KQSNVLRRKTEEAAAANKRLKDAL------QKQREVAD-----KRKETQSRGMEGTAARV 743
KQ L ++ E A +RL++ L ++QREV E ++ M+ A
Sbjct: 527 KQKLALEQRCRELRARGRRLEETLPRRIGSEEQREVLSLLCRVHELEVENTEMQSHALLR 586
Query: 744 KNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQD 777
L + E + E+ + +++++ ++ + D
Sbjct: 587 DGALRHRHEAVRRLEQHRSLCDEIIQGQRQIIDD 620
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 241 bits (616), Expect = 2e-63
Identities = 169/437 (38%), Positives = 248/437 (56%), Gaps = 56/437 (12%)
Query: 46 DKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAE 105
D F +D VFD ++ Q EVF P+++ GYN TVLAYG TG+GKT++M G+
Sbjct: 71 DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS---- 126
Query: 106 QENEPTVGVIPRVIQLLFKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIR 164
+EP GV+ + L+K +D+ K + + VSYLE+YNE+I DLL S A +R
Sbjct: 127 -ADEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLA---VR 180
Query: 165 EDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK 224
ED ++G+ + GLT + + + L+ GN +RT T MN+ SSRSHA+F I L Q+
Sbjct: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
Query: 225 KSDK-NSSFR-SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDK- 281
K+ N + R +K+ L+DLAGSER + A+G R EG NINR LL LGNVI+AL D K
Sbjct: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
Query: 282 KGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKN--- 338
K +PYR+SKLTRLL+DSLGGN T+MIA VSP+ ++T NTL+YA+RA+ IK+
Sbjct: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
Query: 339 KPIVNIDPQTAELNHLKQQV-----QQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQ 393
++N++ NH+ Q V Q+ ++LLL+ E L++ E+ +
Sbjct: 361 SNVLNVN------NHITQYVKICNEQKAEILLLK---------------EKLKA-YEEQK 398
Query: 394 SLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVET 453
+ EN++ +S + + + I+ N EE+RQ + KL
Sbjct: 399 AFTNENDQAKLMISNPQEKEIERFQEILNCLFQNR------EEIRQ------EYLKLEML 446
Query: 454 LEDQELKENVEIICNLQ 470
L++ ELK + C+ Q
Sbjct: 447 LKENELKSFYQQQCHKQ 463
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,393,727
Number of Sequences: 37866
Number of extensions: 2071718
Number of successful extensions: 22592
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 395
Number of HSP's successfully gapped in prelim test: 1233
Number of HSP's that attempted gapping in prelim test: 10308
Number of HSP's gapped (non-prelim): 6226
length of query: 1232
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1118
effective length of database: 13,930,794
effective search space: 15574627692
effective search space used: 15574627692
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.