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Search of human proteins with 116686120
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116686120 periaxin isoform 2 [Homo sapiens]
(1461 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116686120 periaxin isoform 2 [Homo sapiens] 2840 0.0
gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens] 266 8e-71
gi|13491172 periaxin isoform 1 [Homo sapiens] 249 1e-65
gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens] 208 3e-53
gi|110349719 titin isoform N2-A [Homo sapiens] 168 3e-41
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 91 8e-18
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 88 5e-17
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 81 8e-15
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 81 8e-15
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 81 8e-15
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 81 8e-15
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 76 2e-13
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 76 3e-13
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 72 3e-12
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 72 3e-12
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 68 7e-11
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 68 7e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 66 2e-10
gi|61966919 hypothetical protein LOC442444 [Homo sapiens] 66 3e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 8e-10
gi|239753930 PREDICTED: hypothetical protein [Homo sapiens] 59 3e-08
gi|160707881 formin 2 [Homo sapiens] 59 3e-08
gi|239748472 PREDICTED: hypothetical protein [Homo sapiens] 59 3e-08
gi|239742436 PREDICTED: hypothetical protein [Homo sapiens] 59 3e-08
gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens] 59 4e-08
gi|105990532 apolipoprotein B precursor [Homo sapiens] 57 2e-07
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 57 2e-07
gi|110349717 titin isoform novex-2 [Homo sapiens] 56 3e-07
gi|110349713 titin isoform novex-1 [Homo sapiens] 56 3e-07
gi|110349715 titin isoform N2-B [Homo sapiens] 56 3e-07
>gi|116686120 periaxin isoform 2 [Homo sapiens]
Length = 1461
Score = 2840 bits (7361), Expect = 0.0
Identities = 1461/1461 (100%), Positives = 1461/1461 (100%)
Query: 1 MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ 60
MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ
Sbjct: 1 MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ 60
Query: 61 EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP 120
EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP
Sbjct: 61 EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP 120
Query: 121 RAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAVKGPVP 180
RAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAVKGPVP
Sbjct: 121 RAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAVKGPVP 180
Query: 181 AAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPR 240
AAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPR
Sbjct: 181 AAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPR 240
Query: 241 LPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPAL 300
LPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPAL
Sbjct: 241 LPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPAL 300
Query: 301 PSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRL 360
PSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRL
Sbjct: 301 PSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRL 360
Query: 361 SFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTI 420
SFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTI
Sbjct: 361 SFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTI 420
Query: 421 KMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPK 480
KMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPK
Sbjct: 421 KMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPK 480
Query: 481 VPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPE 540
VPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPE
Sbjct: 481 VPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPE 540
Query: 541 VRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKL 600
VRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKL
Sbjct: 541 VRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKL 600
Query: 601 PEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLP 660
PEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLP
Sbjct: 601 PEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLP 660
Query: 661 KVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVP 720
KVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVP
Sbjct: 661 KVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVP 720
Query: 721 DMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAP 780
DMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAP
Sbjct: 721 DMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAP 780
Query: 781 EVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPE 840
EVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPE
Sbjct: 781 EVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPE 840
Query: 841 VDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPS 900
VDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPS
Sbjct: 841 VDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPS 900
Query: 901 VEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVS 960
VEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVS
Sbjct: 901 VEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVS 960
Query: 961 KFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPR 1020
KFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPR
Sbjct: 961 KFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPR 1020
Query: 1021 FALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKEAEVQGDR 1080
FALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKEAEVQGDR
Sbjct: 1021 FALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKEAEVQGDR 1080
Query: 1081 ASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHD 1140
ASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHD
Sbjct: 1081 ASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHD 1140
Query: 1141 AGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQVA 1200
AGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQVA
Sbjct: 1141 AGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQVA 1200
Query: 1201 GGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTLGARARVGGEG 1260
GGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTLGARARVGGEG
Sbjct: 1201 GGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTLGARARVGGEG 1260
Query: 1261 AEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGA 1320
AEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGA
Sbjct: 1261 AEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGA 1320
Query: 1321 EEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPR 1380
EEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPR
Sbjct: 1321 EEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPR 1380
Query: 1381 VGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
VGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV
Sbjct: 1381 VGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
Query: 1441 GFSETGAPGPARMEGAQAAAV 1461
GFSETGAPGPARMEGAQAAAV
Sbjct: 1441 GFSETGAPGPARMEGAQAAAV 1461
>gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]
Length = 5890
Score = 266 bits (681), Expect = 8e-71
Identities = 427/1692 (25%), Positives = 723/1692 (42%), Gaps = 453/1692 (26%)
Query: 92 VSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADL 151
V F LK GD+ + + G E+KGP V + + P + G P
Sbjct: 2317 VDFNLKGPKIKGDVDVSAPKLEG-ELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFK 2375
Query: 152 APVDVEFSFPKFSR--LRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAA 209
P D+ F PK S L LK+ KG V + +P+L + + +
Sbjct: 2376 MP-DMHFKAPKISMPDLDLHLKSPKAKGEVD-------VDVPKLE-----GDLKGPHVDV 2422
Query: 210 AAP------PPRKAKVEAEVAAGARFTAPQVE-------LVGPRLPG-AEVGVPQVSAPK 255
+ P P K K F AP + L GP++ G +V VP+V
Sbjct: 2423 SGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKL 2482
Query: 256 AAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETR 315
P G P + + AP V+AP +++P++++P ++P +
Sbjct: 2483 EVPDMNIRG------PKVDVNAPD---VQAPDWHLKMPKMKMPKF-------SMPGFKAE 2526
Query: 316 EGAVSVVVPT--LDVAAPTV---GVDLALPGAEVEARG---EAPEVALKMPRLSFPRF-- 365
V V +P +D++ P V G D+ + G E + +G + PE+ +K P++S P F
Sbjct: 2527 GPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDL 2586
Query: 366 ---GARAKEVAEAKVAKVS-----PEARVKGPR--LRMPTFGLSLLEPRPAAPEVVESKL 415
G + K + + KV PE +KGP+ + P G+ + P+V K
Sbjct: 2587 HLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKF 2646
Query: 416 KLP---------TIKMPSLGIGVSGPEVKVP------KGPEVKLPKAPEVKLP----KVP 456
+P +K+P I VSGP+V + +GPE KL K P+ K+P K P
Sbjct: 2647 SMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKL-KGPKFKMPEMNIKAP 2705
Query: 457 EAALPEVRLP----------EVELPKVS--------EMKLPKVPEMAVPEV--------- 489
+ ++P++ L +V LPKV ++K PKV ++ P+V
Sbjct: 2706 KISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKV-DIDAPDVDVHGPDWHL 2764
Query: 490 RLPEVELPKVS-----------EMKLPKVP-EMAVP--EVRLPEVQLL-KVSEMKLPK-- 532
++P++++PK+S ++ LPK +++ P +V P+V + + K PK
Sbjct: 2765 KMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFK 2824
Query: 533 VPEM--AVPEVRLPEVQLPKVSEMKLPEVSEVAVPEV----RLPEVQL--PKVPEMKVPE 584
+PEM P++ +P++ L ++ K+ +V P+V + PEV L PKV ++ VP+
Sbjct: 2825 MPEMHFKTPKISMPDIDL-NLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKV-DIDVPD 2882
Query: 585 MKLP------KVPEMKLPEMKLP---------EVQLPKV------PEMAV--PDVHL--P 619
+ + K+P+MK+P+ +P +V LPK P++ V PDV++ P
Sbjct: 2883 VNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGP 2942
Query: 620 EVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMP-EMAVPEV 678
E +L K P+ K+PEM +K PK+P M D+HL ++ ++ LPK+ ++ PEV
Sbjct: 2943 EGKL-KGPKFKMPEMN---IKAPKIP-MPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEV 2997
Query: 679 --RLPEVQL--PKVS------EMKLPKV--PEMAVP---------DVHLPEVQL----PK 713
R P+V + P V +K+PKV P+ ++P DV+LP+ L PK
Sbjct: 2998 DIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPK 3057
Query: 714 VCEMKVPDMKL---------PEIKLP----KVPEMAVPDVHLP----------EVQLPKV 750
V ++ VPD+ + P+ K+P K P++++PD+ L +V LPKV
Sbjct: 3058 V-DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKV 3116
Query: 751 S-EIRLPEMQV--PKV-----------PDVHLPKAPEVKLPR---------APEVQLKAT 787
++++P++ + PKV PD HL K P++K+P+ PEV +
Sbjct: 3117 EGDMKVPDVDIKGPKVDINAPDVDVQGPDWHL-KMPKIKMPKISMPGFKGEGPEVDVNLP 3175
Query: 788 KAE---------------QAEGMEFGFKMPKMTMPKLGRAESPSRGKP------------ 820
KA+ EG + K PK MP++ ++P P
Sbjct: 3176 KADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMN-IKAPKISMPDLDLNLKGPKMK 3234
Query: 821 GEAG---AEVSGKLV--TLPCLQPEVDGEA----------------------HVGVPSLT 853
GE A V G L L P++D +A HV +P ++
Sbjct: 3235 GEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKIS 3294
Query: 854 LPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEI 913
+P ++L+L G+ L+G V V GP++ ++ PS++I P+ V++
Sbjct: 3295 MPEIDLNLKGSK-LKGDVD---------VSGPKLEGDIK-----APSLDIKGPE---VDV 3336
Query: 914 EEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGA 973
+L IE K K S+F LPKF SG KV E + G+ + ++ PK + A
Sbjct: 3337 SGPKLN-IEGKSK-KSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITG-----PKVDINA 3389
Query: 974 ---EAEAKGAGEAGLLPALDLSIPQLSL---DAHLPSGKV----EVAGADLK--FKGPRF 1021
E + K G +P L +S P++S+ + +L S KV ++AG +L+ FKGP+
Sbjct: 3390 PDVEVQGKVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKV 3449
Query: 1022 ALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLA------------ 1069
D +A E+ +++ G W+ +KMPK+KMP F ++
Sbjct: 3450 ----------DIKAPEVNLNAPDVDVHGPDWN--LKMPKMKMPKFSVSGLKAEGPDVAVD 3497
Query: 1070 ---------------RGKEAEVQGDRAS-PGEKAESTAVQLKIPEVELVTLGAQEEG--- 1110
G + V+G G K + + +K P++ + + +G
Sbjct: 3498 LPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKV 3557
Query: 1111 ---------RAEGAVAVSGMQLSGLKVS-TAGQVVTEGHDAGLRMPPLGISLPQVELTGF 1160
+ EG + + + G KV A V G D L+MP + +P+ + GF
Sbjct: 3558 KGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPK--VKMPKFSMPGF 3615
Query: 1161 -GEAGTPGQQAQSTVPSAE---GTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTV 1216
GE G + T+P A+ V VP V + P A++ G + + E K P +
Sbjct: 3616 KGE----GPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKI 3671
Query: 1217 TVPQLELDVGLSREAQAGEAATG----EGGLR-----LKLPTLGA-RARVGGEGAEEQPP 1266
++P + D+ L G+ EG L+ +K P + + EG+E +
Sbjct: 3672 SMP--DFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFK 3729
Query: 1267 GAE--------RTFCLSLPDVELS---PSGGNHAEYQVAEGEGE-AGHKLKVRLPRFGLV 1314
G + + +S+PD++L+ P + + + EG+ G ++ ++ P+ +
Sbjct: 3730 GPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVD-I 3788
Query: 1315 RAKEGAEEGE--KAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRG 1372
A + +G K PK+++P+ FS GEG + + + SG
Sbjct: 3789 NAPDVDVQGPDWHLKMPKVKMPK--FSMPGF-KGEGPDVDVNLPKADLDVSG-------- 3837
Query: 1373 RVRVRLPRVGLAAPSKASRGQEGD-AAPKSPVRE---KSPKFRFPRVSLSPKARSGSGDQ 1428
P+V + P G EG PK + E K+PK P + L+ K G +
Sbjct: 3838 ------PKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK-----GPK 3886
Query: 1429 EEGGLRVRLPSV 1440
+G + V LP V
Sbjct: 3887 VKGDMDVSLPKV 3898
Score = 250 bits (638), Expect = 8e-66
Identities = 398/1620 (24%), Positives = 705/1620 (43%), Gaps = 380/1620 (23%)
Query: 101 PTGDLALRPGTVSGYE--IKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEF 158
P D+ + + G E +KGP+ K+ ++NI++ K M L + D++
Sbjct: 3838 PKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKA----PKISMPDIDLNLKGPKVKGDMDV 3893
Query: 159 SFPKFSRLRRGLKAEAVKGP-----VPAAPARR---RLQLPRLRVR------------EV 198
S PK + + +KGP P R L++P++++ EV
Sbjct: 3894 SLPKVEGDMQVPDLD-IKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEV 3952
Query: 199 AEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPR--LPGAEVGVPQVSAPKA 256
A L + P KV+ +V P +L GP+ +P + P++S P
Sbjct: 3953 DVNLPKADLDVSGP-----KVDVDVP-DVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDF 4006
Query: 257 ---APSAEAAGGFALHLPTLGLGAPAPPA-VEAPAVGIQVPQVELPALPSLPTLP----- 307
+ G + LP + AP ++ P V I P V++ +P
Sbjct: 4007 DLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMP 4066
Query: 308 --TLPCLETREGAVSVVVPT--LDVAAPTVGVD---LALPGAEVEARG---EAPEVALKM 357
++P + V V +P +DV+ P V +D + + G E + +G + P++ LK
Sbjct: 4067 KFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKA 4126
Query: 358 PRLSFPRF-----GARAKEVAEAKVAKVS-----PEARVKGPRLRMPTFGLSLLEP--RP 405
P++S P G + K + + KV PE +KGP++ + + + P
Sbjct: 4127 PKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHL 4186
Query: 406 AAPEVVESKLKLPTIK---------MPSLGIGVSGPEVKVP------KGPEVKLPKAPEV 450
P+V K +P K +P + VSGP+V + +GP+ KL K P+
Sbjct: 4187 KMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKL-KGPKF 4245
Query: 451 KLPKVPEAALPEVRLPEVEL----PKVS---EMKLPKVP-EMAVPEVRLP----EVELPK 498
K+P++ A P++ +P+ +L PKV ++ LPKV ++ PEV + +++ P
Sbjct: 4246 KMPEMNIKA-PKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPD 4304
Query: 499 VS------EMKLPKV--PEMAVP---------EVRLPEVQLLKVSEMKLPKVPEMAVPEV 541
V +K+PKV P+ ++P +V LP+ + E+ PKV ++ P+V
Sbjct: 4305 VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADI----EISGPKV-DIDAPDV 4359
Query: 542 RL--PEVQLPKVSEMKLPEVSEVAVPEVRLPE---------------VQLPKVP-EMKVP 583
+ P+ +L K + K+PE++ + P++ +P+ V LPKV ++K P
Sbjct: 4360 SIEGPDAKL-KGPKFKMPEMN-IKAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGP 4417
Query: 584 EMKL---------PKV----PEMKL--PEMKLPEVQLPKVPEMAVPD--VHLP------- 619
E+ + P V PE KL P+ K+PE+ + K P++++PD +HL
Sbjct: 4418 EIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNI-KAPKISMPDFDLHLKGPKVKGD 4476
Query: 620 -EVQLPKVP-EMKLPEMKL--PEVKLPKVPEMAVPDVHL--PEVQLPKVP-EMKLPKMP- 671
+V LPKV ++K PE+ + PE KL K P+ +PDVH P++ + + +K PK+
Sbjct: 4477 VDVSLPKVESDLKGPEVDIEGPEGKL-KGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKG 4535
Query: 672 --EMAVPEVRLPEVQLPKVSEMKLPKV----PEMAVPDVHLPEVQLPKVCEMKVPDMKLP 725
+++VP++ +++ PKV ++K PKV P++ D+H PE +L K P K+P
Sbjct: 4536 DMDISVPKLE-GDLKGPKV-DVKGPKVGIDTPDI---DIHGPEGKL------KGPKFKMP 4584
Query: 726 EIKLPKVPEMAVPDVHLP----------EVQLPKVS-EIRLPEMQV--PKV--------- 763
++ L K P++++P+V L ++ LPKV +++ PE+ + PKV
Sbjct: 4585 DLHL-KAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDV 4643
Query: 764 --PDVHLPKAPEVKLPR---------APEVQLKATKAE---------------QAEGMEF 797
PD HL K P+VK+P+ P+V + KA+ EG +
Sbjct: 4644 QGPDWHL-KMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDA 4702
Query: 798 GFKMPKMTMPKLGRAESPSRGKP----GEAGAEVSGKL-VTLPCLQPEVDG-EAHVGVPS 851
K PK MP++ ++P P G +V G + VTLP ++ ++ G EA + P
Sbjct: 4703 KLKGPKFKMPEMS-IKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPK 4761
Query: 852 LTLPSVELDLPGALGLQGQVPAAKMGK----GERVEGPEVAAGVREVGFRVPSVEIVTPQ 907
+ + + ++D+ G ++P KM K G + EGP+V +V +++ P+
Sbjct: 4762 VDINTPDVDVHGP-DWHLKMPKVKMPKFSMPGFKGEGPDV-----DVSLPKADIDVSGPK 4815
Query: 908 LPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLP 967
+ V+I + +E + K+K KF +P+ + PK++ + + + K+K F +S+P
Sbjct: 4816 VD-VDIPDVNIEGPDAKLK-GPKFKMPEINIKAPKISIPDVDLDLKGPKVK-GDFDVSVP 4872
Query: 968 KAR---VGAEAEAKG------------AGEAGLLPALDLSIPQLS---LDAHLPSGKV-- 1007
K G E + KG +G + +P+L++S P+++ +D HL + K+
Sbjct: 4873 KVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF 4932
Query: 1008 ---EVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKLKMP 1064
++ G ++ KGP+ P V + +EG VK+PK K P
Sbjct: 4933 SGPKLEGGEVDLKGPKVEAPSLDVHMDSPDI--------NIEGPD------VKIPKFKKP 4978
Query: 1065 SFGL-ARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQL 1123
FG A+ +A+++ S + L+ PE+ + G + + + + +SG ++
Sbjct: 4979 KFGFGAKSPKADIKSP--SLDVTVPEAELNLETPEISVGGKGKKSKFKMP-KIHMSGPKI 5035
Query: 1124 SGLKVSTAGQVVTEGHDAGLRMPPLGISL-------------PQVELTGFG--------- 1161
K V DA L+ P + +++ P+ + T FG
Sbjct: 5036 KAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEF 5095
Query: 1162 EAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTV--TVP 1219
+ +P +A++ +PS + +Q P + LSLP V G ++ KMP V +VP
Sbjct: 5096 DIKSPKFKAEAPLPSPKLEG--ELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVP 5153
Query: 1220 QLELDV-GLSREAQAGEAATGEGGL--RLKLPTLGARARVGGEGAEEQPPGAERTFCLSL 1276
++E D+ G +A G GL ++K P+ G A +S+
Sbjct: 5154 KIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQ-----------------VSI 5196
Query: 1277 PDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGE-KAKSPKLRLPR 1335
PDV ++ G K+K +P GL + E K K PK +P+
Sbjct: 5197 PDVNVNLKGP----------------KIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPK 5240
Query: 1336 VGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEG 1395
+G +M EG + + EG G P V L P + +G
Sbjct: 5241 IGIPGVKM---EGGGAEVHAQLPSLEGDLRG------------PDVKLEGPDVSLKGPGV 5285
Query: 1396 DAAPKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSVGFSETGAPGPARMEG 1455
D V PK P + L+ K S GD + +++ + G + +G G ++ G
Sbjct: 5286 DLPS---VNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGG 5342
Score = 248 bits (633), Expect = 3e-65
Identities = 395/1534 (25%), Positives = 672/1534 (43%), Gaps = 350/1534 (22%)
Query: 116 EIKGPRAKVAKLNIQ----SLSPVKKKKMVPGALG--------VPADLAPVDVEFSFPKF 163
++KGP+ K+ ++NI+ S+ V P G V +++ DVE K
Sbjct: 800 KLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVEL---KS 856
Query: 164 SRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAAR-------LAAAAPPPRK 216
+++ + V+GP L++P++++ + + A L A
Sbjct: 857 AKMDIDVPDVEVQGP------DWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISG 910
Query: 217 AKVEAEVAAGARFTAPQVELVGPR--LPGAEVGVPQVSAPKA---APSAEAAGGFALHLP 271
KV EV P+ +L GP+ +P + P++S P + G + + +P
Sbjct: 911 PKVGVEVP-DVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVP 969
Query: 272 TLGLGAPAPPA-VEAPAVGIQ-------VPQVELPALPSLPTLPTLPCLETREGAVSVVV 323
L P V AP V +Q +P++++P S+P+L E E V++
Sbjct: 970 KLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKF-SMPSLKG----EGPEFDVNLSK 1024
Query: 324 PTLDVAAPTVGV---DLALPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEV 372
+D++AP V DL+L G E + +G + PE+ + P++S P G + K
Sbjct: 1025 ANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGN 1084
Query: 373 AEAKVAKVS-----PEARVKGPR--LRMPTFGLSLLEPRPAAPEVVESKLKLPTIK---- 421
+ K+ P+ ++GP+ ++ P L+ P++ K +P++K
Sbjct: 1085 VDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGP 1144
Query: 422 -----MPSLGIGVSGPEVKVP------KGPEVKLPKAPEVKLPKVPEAALPEVRLPEVEL 470
+P + VSGP+V + +GPE KL K P+ K+P++ P++ +P+V+L
Sbjct: 1145 EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKL-KGPKFKMPEM-HFKTPKISMPDVDL 1202
Query: 471 ----PKVS---EMKLPKVP-EMAVPEVRLP----EVELPKVSEMKLP----KVPEMAVPE 514
PKV ++ +PKV EM VP+V + +++ P V E++ P K+P+M +P+
Sbjct: 1203 HLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDV-EVQGPDWHLKMPKMKMPK 1261
Query: 515 VRLP---------EVQLLKVS-EMKLPKVPEMAVPEVRL--PEVQLPKVSEMKLPEVSEV 562
+P +V L K ++ PKV ++ VP+V L PE +L K + K+PE+
Sbjct: 1262 FSMPGFKGEGREVDVNLPKADIDVSGPKV-DVEVPDVSLEGPEGKL-KGPKFKMPEMHFK 1319
Query: 563 AVPEVRLPEVQLP-KVPEMKVP-EMKLPKVP-EMKLPEMKLPEVQLPKVPEMAVPDV--H 617
A P++ +P+V L K P++K ++ LP+V EMK+P++ +++ PKV +++ PDV H
Sbjct: 1320 A-PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDV---DIKGPKV-DISAPDVDVH 1374
Query: 618 LPEVQLPKVPEMKLPEMKLP---------EVKLPKV------PEM--AVPDVHL--PEVQ 658
P+ L K+P++K+P+ +P +VKLPK P+M VPDV++ P+ +
Sbjct: 1375 GPDWHL-KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAK 1433
Query: 659 LPKVPEMKLPKMP----EMAVPEVRLP----------EVQLPKVS--------EMKLPKV 696
L K P+ K+P+M ++++P+V L +V +PKV ++K PKV
Sbjct: 1434 L-KGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKV 1492
Query: 697 ----PEMAV--PDVHL--PEVQLPKVC------EMKVPDMKLPEIKL----PKVPEMAVP 738
P++ V PD HL P+V++PK E DM LP+ L PKV ++ VP
Sbjct: 1493 DINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKV-DIDVP 1551
Query: 739 DVHL--PEVQLPKVSEIRLPEMQVP----KVPDVHLP-KAPEVK------LPRA------ 779
DV+L PE +L K + ++P M + +PDV L KAP++K LP+
Sbjct: 1552 DVNLEAPEGKL-KGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKG 1610
Query: 780 PEVQLKATKAE------QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGE----AGAEVSG 829
PE+ +KA K + EG E K PK MP++ ++P P G +V G
Sbjct: 1611 PEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEM-HFKAPKISMPDVDLHLKGPKVKG 1669
Query: 830 KLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGAL----GLQGQVPAAKMGK----GER 881
+ P+V+GE V + P V++D P ++P KM K G +
Sbjct: 1670 DM---DVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFK 1726
Query: 882 VEGPEVAAGVREVGFRV--PSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLS 939
EGPEV + + V PSV+ P L +E EG+L+ SKF +PK +
Sbjct: 1727 AEGPEVDVNLPKADIDVSGPSVDTDAPDLD-IEGPEGKLK--------GSKFKMPKLNIK 1777
Query: 940 GPKVAKAEAEGAGRATKLKVSKFAISLPKARV---GAEAEAKGAGEAGLLPALDLSIPQL 996
PKV+ + + + KLK + S+P+ G + + KG +P +DL P
Sbjct: 1778 APKVSMPDVDLNLKGPKLK-GEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECP-- 1834
Query: 997 SLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRV 1056
D K KGP+F +P+
Sbjct: 1835 ----------------DAKLKGPKFKMPEM----------------------------HF 1850
Query: 1057 KMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAEST--AVQLKIPEVELVTLGAQEEGRAE 1113
K PK+ MP L +G + + D + P + + T +V +++P+VEL A+ +G
Sbjct: 1851 KAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPK- 1909
Query: 1114 GAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQST 1173
+ M K+S MP + + L ++ G + P + T
Sbjct: 1910 --FKMPDMHFKAPKIS---------------MPDVDLHLKGPKVKGDVDVSVPKLEGDLT 1952
Query: 1174 VPSAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQA 1233
PS V+VP V L P A++ G + + E FK P +++P ++L + +
Sbjct: 1953 GPSVG------VEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGD 2006
Query: 1234 GEAATGEGGLRLKLPTL---GARARVGGEGAEEQPPGAE-RTFCLSLPDVELSPSGGNHA 1289
+ + + +K+P + G + + + P + + +P +
Sbjct: 2007 MDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGP 2066
Query: 1290 EYQVAEGEGE---AGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEM--- 1343
E V + + +G K+ V +P L EG E K K PKL++P + F ++
Sbjct: 2067 EVDVNLPKADVVVSGPKVDVEVPDVSL----EGPE--GKLKGPKLKMPEMHFKAPKISMP 2120
Query: 1344 -----VTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAA 1398
+ G + + EG G S V V +P V L P +G
Sbjct: 2121 DVDLHLKGPKVKGDVDVSLPKLEGDLTGPS-----VDVEVPDVELECPDAKLKG------ 2169
Query: 1399 PKSPVRE---KSPKFRFPRVSLSPKARSGSGDQE 1429
PK + E K+PK P V+L+ K GD +
Sbjct: 2170 PKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMD 2203
Score = 244 bits (623), Expect = 4e-64
Identities = 411/1642 (25%), Positives = 711/1642 (43%), Gaps = 396/1642 (24%)
Query: 92 VSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADL 151
V LK GDL + + G + KGP+ + + +P L +P
Sbjct: 3420 VELNLKSPKVKGDLDIAGPNLEG-DFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMP--- 3475
Query: 152 APVDVEFSFPKFSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAA 211
+ PKFS GLKAE V ++ P + + +
Sbjct: 3476 -----KMKMPKFSV--SGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKG 3528
Query: 212 PPPRKAKVEAEVAAGARFTAPQVEL--VGPRLPG-AEVGVPQVSAPKAAPSAEAAGGFAL 268
P K K+ + + P ++L GP++ G ++ +P++ P + G
Sbjct: 3529 P---KFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKG---- 3581
Query: 269 HLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPT--L 326
P + + AP V P +++P+V++P ++P + V V +P +
Sbjct: 3582 --PKVDINAPDVD-VHGPDWHLKMPKVKMPKF-------SMPGFKGEGPEVDVTLPKADI 3631
Query: 327 DVAAPTVGVDLA---LPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEVAEA 375
D++ P V VD+ + G + + +G + PE+ +K P++S P F G + K
Sbjct: 3632 DISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDVVV 3691
Query: 376 KVAKVS-----PEARVKGPRLRMPTFGLSL--LEPRPAAPE--VVESKLKLPTIKMPSLG 426
+ KV PE +KGP++ + T +++ E + P+ + E LK P I MP +
Sbjct: 3692 SLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDID 3751
Query: 427 IGVSGPEVK------VPK------GPEVKL--PK----APEV---------KLPKV--PE 457
+ + GP+VK +PK GPEV + PK AP+V K+PKV P+
Sbjct: 3752 LNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPK 3811
Query: 458 AALP---------EVRLPEVEL----PKVS-------------EMKLPK--VPEMAV--P 487
++P +V LP+ +L PKV ++K PK +PEM + P
Sbjct: 3812 FSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAP 3871
Query: 488 EVRLPEVEL----PKVS---EMKLPKVP-EMAVPE---------VRLPEVQL------LK 524
++ +P+++L PKV ++ LPKV +M VP+ + P+V + LK
Sbjct: 3872 KISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLK 3931
Query: 525 VSEMKLPKVP------EMAVPEVRLPEVQL----PKVSEMKLPEVS------EVAVPEVR 568
+ ++K+PK+ E +V LP+ L PKV ++ +P+V+ ++ P+ +
Sbjct: 3932 MPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKV-DVDVPDVNIEGPDAKLKGPKFK 3990
Query: 569 LPEVQLPKVPEMKVPEMKL----PKVP---EMKLPEM----KLPEVQL--PKVPEMAVPD 615
+PE+ + K P++ +P+ L PKV ++ LP+M K PEV + PKV ++ PD
Sbjct: 3991 MPEMNI-KAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKV-DIDAPD 4048
Query: 616 V--HLPEVQLPKVPEMKLPEMKLP---------EVKLPKV------PEMAVP----DVHL 654
V H P+ L K+P++K+P+ +P +V LPK P++ + D+H
Sbjct: 4049 VDVHGPDWHL-KMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHG 4107
Query: 655 PEVQLPKVPEMKLP----KMPEMAVPEVRLP----------EVQLPKVS--------EMK 692
PE +L K P+ K+P K P++++PEV L +V LPKV ++K
Sbjct: 4108 PEGKL-KGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIK 4166
Query: 693 LPKV----PEMAV--PDVHL--PEVQLPKVC------EMKVPDMKLPEIKL----PKVPE 734
PKV P++ V PD HL P+V++PK E D+ LP+ L PKV +
Sbjct: 4167 GPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKV-D 4225
Query: 735 MAVPDVHL--PEVQLPKVSEIRLPEMQVPKVPDVHLP------KAPEVK------LPRA- 779
+ VPDV++ P+ +L K + ++PEM + K P + +P K P+VK LP+
Sbjct: 4226 IDVPDVNIEGPDAKL-KGPKFKMPEMNI-KAPKISMPDFDLHLKGPKVKGDVDVSLPKVE 4283
Query: 780 -----PEVQLKATKAE------QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVS 828
PEV +K K + G ++ KMPK+ MPK G GE G +V
Sbjct: 4284 GDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMP-----GFKGE-GPDVD 4337
Query: 829 GKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEV- 887
VTLP E+ G P V++D P + ++G P AK+ KG + + PE+
Sbjct: 4338 ---VTLPKADIEISG-----------PKVDIDAPD-VSIEG--PDAKL-KGPKFKMPEMN 4379
Query: 888 ----AAGVREVGFRVPSVEI---VTPQLPAVEIEEGRLEMIETKVK-PSSKFSLPKFGLS 939
+ ++ F + ++ V LP VE G L+ E +K PS P +
Sbjct: 4380 IKAPKISMPDIDFNLKGPKVKGDVDVSLPKVE---GDLKGPEIDIKGPSLDIDTPDVNIE 4436
Query: 940 GPKVAKAEAEGAGRATKLKVSKFAISLPKARV-GAEAEAKGAGEAGLLPALDLSIPQLSL 998
GP EG + K K+ + I PK + + KG G +D+S+P++
Sbjct: 4437 GP-------EGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKG---DVDVSLPKVES 4486
Query: 999 DAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAEL--------VPG-----VAEL 1045
D P +V++ G + K KGP+F +P + +++ + G V +L
Sbjct: 4487 DLKGP--EVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKL 4544
Query: 1046 EGKGWGWDGRVKMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTL 1104
EG G VK PK+ + + + G E +++G + + A ++ +PEV+L
Sbjct: 4545 EGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMPD-LHLKAPKISMPEVDLNLK 4603
Query: 1105 GAQEEG-------RAEGAVAVSGMQLSGLKVS-TAGQVVTEGHDAGLRMPPLGISLPQVE 1156
G + +G + EG + + + KV V +G D L+MP + +P+
Sbjct: 4604 GPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPK--VKMPKFS 4661
Query: 1157 LTGF-GEAGTPGQQAQSTVPSAE-GTAGYR--VQVPQVTLSLPGAQVAGGELLVGEGVFK 1212
+ GF GE G +P A+ +G + V VP V + P A++ G + + E K
Sbjct: 4662 MPGFKGE----GPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIK 4717
Query: 1213 MPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL-----GARARVGGEGAEEQPPG 1267
P +++P ++L++ + +G + + LP + G A + G + P
Sbjct: 4718 APKISMPDIDLNL---------KGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPD 4768
Query: 1268 AE---RTFCLSLPDVELSPSG-----GNHAEYQVAEGEGE---AGHKLKVRLPRFGLVRA 1316
+ + L +P V++ G + V+ + + +G K+ V +P +
Sbjct: 4769 VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNI--- 4825
Query: 1317 KEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRV 1376
EG + K K PK ++P + ++ P + + + + S + +
Sbjct: 4826 -EGPD--AKLKGPKFKMPEINIKAPKI----SIPDVDLDLKGPKVKGDFDVSVPKVEGTL 4878
Query: 1377 RLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSLS-PKARSGSGDQEEGGLRV 1435
+ P V L P G + + P + P + +S PK + D L +
Sbjct: 4879 KGPEVDLKGPRLDFEGPD--------AKLSGPSLKMPSLEISAPKVTAPDVD-----LHL 4925
Query: 1436 RLPSVGFSETGAPGPARMEGAQ 1457
+ P +GFS GP ++EG +
Sbjct: 4926 KAPKIGFS-----GP-KLEGGE 4941
Score = 243 bits (620), Expect = 1e-63
Identities = 429/1663 (25%), Positives = 697/1663 (41%), Gaps = 434/1663 (26%)
Query: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175
++KGP+ K+ ++NI++ K M L + + + + PK +G K +
Sbjct: 928 KLKGPKFKMPEMNIKA----PKISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVS 983
Query: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVE 235
V L++P++++ + + + KA V+ A AP +
Sbjct: 984 APDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDIS-APKVDTNAPDLS 1042
Query: 236 LVGP--RLPGAEVGVPQVS--APKAA--------PSAEAAGGFALHLPTLGLGAPAPPA- 282
L GP +L G + +P++ APK + + G + P + P
Sbjct: 1043 LEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVD 1102
Query: 283 VEAPAVGIQVPQVELPALPSLPTLP-------TLPCLETREGAVSVVVPTLDV--AAPTV 333
+ P V I+ P VE L +P ++P L+ V V +P DV + P V
Sbjct: 1103 IRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKV 1162
Query: 334 GV---DLALPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEVAEAKVAKVS- 381
+ D++L G E + +G + PE+ K P++S P G + K + V KV
Sbjct: 1163 DIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEG 1222
Query: 382 ----PEARVKGPRLRMPTFGLSLLEP--RPAAPEVVESKLKLPTIK---------MPSLG 426
P+ +KGP++ + + + P P++ K +P K +P
Sbjct: 1223 EMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKAD 1282
Query: 427 IGVSGPEVKVP------KGPEVKLPKAPEVKLP----KVPEAALPEVRLP---------- 466
I VSGP+V V +GPE KL K P+ K+P K P+ ++P+V L
Sbjct: 1283 IDVSGPKVDVEVPDVSLEGPEGKL-KGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDV 1341
Query: 467 EVELPKVS-EMKLPKVP------EMAVPEV---------RLPEVELPKVS---------- 500
+V LP+V EMK+P V +++ P+V ++P+V++PK S
Sbjct: 1342 DVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPE 1401
Query: 501 -EMKLPKV------PEM--AVPEVRL--PEVQL----LKVSEMKLPKVPEMAVPEVRLP- 544
++KLPK P+M VP+V + P+ +L K+ EM + K ++++P+V L
Sbjct: 1402 VDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSI-KPQKISIPDVGLHL 1460
Query: 545 ---------EVQLPKVS-EMKLPEVS------EVAVPEVRL--PEVQLPKVPEMKVPEMK 586
+V +PKV E+K P+V ++ P+V + P+ L K+P++K+P+
Sbjct: 1461 KGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHL-KMPKVKMPKFS 1519
Query: 587 LP----KVPEMKLPEMKLPEVQL----PKVPEMAVPDVHL--PEVQLPKVPEMKLPEMKL 636
+P + PE+ +M LP+ L PKV ++ VPDV+L PE +L K P+ K+P M +
Sbjct: 1520 MPGFKGEGPEV---DMNLPKADLGVSGPKV-DIDVPDVNLEAPEGKL-KGPKFKMPSMNI 1574
Query: 637 -------PEVKLP-KVPEMAVP-DVHLPEVQ-----------LPKV-----------PEM 665
P+V L K P++ DV LP+V+ PK+ PE
Sbjct: 1575 QTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPEG 1634
Query: 666 KLP----KMPEM--AVPEVRLPEVQL----PKVS---EMKLPKVP-EMAVPDVHLP---- 707
KL KMPEM P++ +P+V L PKV ++ +PKV EM VPDV +
Sbjct: 1635 KLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKV 1694
Query: 708 EVQLPKV------CEMKVPDMKLPEIKLP----KVPEMAV------------------PD 739
++ P V +K+P MK+P+ +P + PE+ V PD
Sbjct: 1695 DIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPD 1754
Query: 740 VHL--PEVQLPKVSEIRLPEMQV--PKV--PDVHLP-KAPEVK------LP------RAP 780
+ + PE +L K S+ ++P++ + PKV PDV L K P++K +P R P
Sbjct: 1755 LDIEGPEGKL-KGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGP 1813
Query: 781 EVQLKATKAE------QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTL 834
+V +K E E + K PK MP++ ++P P V L
Sbjct: 1814 QVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEM-HFKAPKISMPD----------VDL 1862
Query: 835 PCLQPEVDGEAHVGVPSLT-----------LPSVELDLPGALGLQGQVPAAKMG----KG 879
P+V G+A V VP L +P VEL+ P A L+G P KM K
Sbjct: 1863 HLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAK-LKG--PKFKMPDMHFKA 1919
Query: 880 ERVEGPEVAAGVR------EVGFRVPSVE-IVTPQLPAVEIEEGRLEMIETKVKPSSKFS 932
++ P+V ++ +V VP +E +T VE+ + LE + K+K KF
Sbjct: 1920 PKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLK-GPKFK 1978
Query: 933 LPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLS 992
+P+ PK++ + + + K+K +S+PK E E K +P +D+
Sbjct: 1979 MPEMHFKTPKISMPDVDLHLKGPKVK-GDMDVSVPKV----EGEMK-------VPDVDIK 2026
Query: 993 IPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAEL-------------- 1038
P++ +DA V+V G D K P+ +PKF + G E E+
Sbjct: 2027 GPKMDIDAP----DVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGP 2082
Query: 1039 -----VPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKEA------------------- 1074
VP V+ LEG +G++K PKLKMP K +
Sbjct: 2083 KVDVEVPDVS-LEGP----EGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDV 2137
Query: 1075 ---EVQGDRASPGEKAESTAVQLK------------------------IPEVELVTLGAQ 1107
+++GD P E V+L+ +P+V L G +
Sbjct: 2138 SLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPK 2197
Query: 1108 EEG-------RAEGAVAVSGMQLSGLKVST-AGQVVTEGHDAGLRMPPLGISLPQVELTG 1159
+G + EG + V + + G KV A V G D L+MP + +P+ + G
Sbjct: 2198 VKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKM--KMPKFSMPG 2255
Query: 1160 F-GEAGTPGQQAQSTVPSAE-GTAGYRV--QVPQVTLSLPGAQVAGGELLVGEGVFKMPT 1215
F GE G + +P A+ +G +V +VP V+L P ++ G + + E FK P
Sbjct: 2256 FKGE----GPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKTPK 2311
Query: 1216 VTVPQLEL---------DVGLSREAQAGEAATGEGGLRLKLPTLGA-RARVGGEGAE--- 1262
+++P ++ DV +S GE E L +K P L A V EG
Sbjct: 2312 ISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPE--LDVKGPKLDADMPEVAVEGPNGKW 2369
Query: 1263 -----EQPPGAERTFCLSLPDVEL---SPSGGNHAEYQVAEGEGE-AGHKLKVRLPRFGL 1313
+ P + +S+PD++L SP + V + EG+ G + V P
Sbjct: 2370 KTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDID- 2428
Query: 1314 VRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEE---EEEEGSGEGASGR 1370
+ EG +G K K P + S ++ P + + + E EG E
Sbjct: 2429 IEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPD-- 2486
Query: 1371 RGRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFP 1413
+ +R P+V + AP Q D K P + K PKF P
Sbjct: 2487 ---MNIRGPKVDVNAPDV----QAPDWHLKMP-KMKMPKFSMP 2521
Score = 240 bits (613), Expect = 6e-63
Identities = 412/1746 (23%), Positives = 714/1746 (40%), Gaps = 416/1746 (23%)
Query: 18 EIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFENFKY 77
E+++ +G G+ +A +G+FV+E+ ++SPAAR+ ++EGDQ++ A ++F+N +
Sbjct: 9 ELLLPNWQGSGSHGLTIAQRD-DGVFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQS 67
Query: 78 EDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLN-----IQSL 132
+ +LL + V L R GD + PG E+ + L+ Q +
Sbjct: 68 GEVTQLLNTMGHHTVGLKLHR---KGDRSPEPGQTWTREVFSSCSSEVVLSGDDEEYQRI 124
Query: 133 SPVKKKKMVPGALGVPADLAPVDVE--------FSFPKFSRLRRGLKAEAVKGPVPAAPA 184
K K + GV DL ++ R G K + P
Sbjct: 125 YTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSP------ 178
Query: 185 RRRLQLPRLRVREVAE---EAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPRL 241
++++PR + E++ E Q+ + P A A R A + GP L
Sbjct: 179 EFKIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIR--AGAISASGPEL 236
Query: 242 PGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVE-APAVGIQVPQVELPAL 300
GA QV+ P A L G G PAV+ + ++G + +V+ P+L
Sbjct: 237 QGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSL 296
Query: 301 PS-------LPTL--PTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAP 351
S PT+ P REG P G+ ++ P V +G P
Sbjct: 297 ESGDHGKIKFPTMKVPKFGVSTGREG-----------QTPKAGLRVSAPEVSVGHKGGKP 345
Query: 352 EVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPT----FGLSLLEPR--- 404
+ ++ P+L EV+ E ++KGP++ P+ GL +P+
Sbjct: 346 GLTIQAPQL----------EVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHI 395
Query: 405 ---PAAPEVVES------KLKLPTIKMPSLGIGVSGPEVKVPK-----------GPEVKL 444
+AP++ S +++ P I + G ++ P++KVPK G +V L
Sbjct: 396 GVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTL 455
Query: 445 PKAPEVKLPKVP-EAALPEVRLPEVELPKVSEMKLPKVPEMAV--PEVRLPEVEL----P 497
P EV +P V + +LPE+ +E K+ K+ K PEM + P++ + +V+L P
Sbjct: 456 PTG-EVTVPGVSGDVSLPEIATGGLE-GKMKGTKV-KTPEMIIQKPKISMQDVDLSLGSP 512
Query: 498 KV-SEMKLP--------KVPEMAVP----EVRLPEVQ------------------LLKVS 526
K+ ++K+ K P++A+ ++ P ++ + +S
Sbjct: 513 KLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMS 572
Query: 527 EMKLPKVPEMAVPEVR-LPEVQLPKV-SEMKLPEVS------EVAVPEVRL--PEVQLPK 576
E+ L +A P+V+ +V LP+V ++K+PEV +V+ P+V PE L K
Sbjct: 573 EVDL----NVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNL-K 627
Query: 577 VPEMKVPEMKLP-----------------------------------------KVPEMKL 595
+P+MK+P P K P++KL
Sbjct: 628 MPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDVKL 687
Query: 596 PEM--KLPEVQLPKVP------------EMAVP------------------DVHLPEVQL 623
P+M K P++ +P V ++ VP DVH P+ L
Sbjct: 688 PDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHL 747
Query: 624 PKVPEMKLPEMKLP---------EVKLPKVP--------EMAVPDVHL--PEVQLPKVPE 664
K+P+MK+P+ +P +V LPK ++ PDV + PE +L K P+
Sbjct: 748 -KMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVSIEEPEGKL-KGPK 805
Query: 665 MKLPKMPEMAVPEVRLPEVQL----PKVS---EMKLPKV-PEMAVPDVHLP----EVQLP 712
K+P+M + VP++ +P+V L P V ++ +PKV E+ VPDV L ++ +P
Sbjct: 806 FKMPEM-NIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVP 864
Query: 713 KVCEMKVPD--MKLPEIKLPKV---------PE------------------MAVPDVHL- 742
V E++ PD +K+P++K+PK PE + VPDV++
Sbjct: 865 DV-EVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIE 923
Query: 743 -PEVQLPKVSEIRLPEMQV--PKV--PDVHL-PKAPEVK------LP------RAPEVQL 784
PE +L K + ++PEM + PK+ PDV L K P+VK +P + P+V +
Sbjct: 924 GPEGKL-KGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDV 982
Query: 785 KATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKP-----GEAGAEVSGKLVTLPCLQP 839
A E +G ++ KMPK+ MPK G +A ++S V
Sbjct: 983 SAPDVEM-QGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDL 1041
Query: 840 EVDG-------------EAHVGVPSLTLPSVELDLPG----------ALGLQG--QVPAA 874
++G E H P ++LP V+LDL G A ++G QVP
Sbjct: 1042 SLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDV 1101
Query: 875 KM-GKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSL 933
+ G ++ P+V + ++P +++ +P+++ E +++ K S
Sbjct: 1102 DIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDV--NLPKADVVVSG 1159
Query: 934 PKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARV-GAEAEAKGAGEAGLLPALDLS 992
PK + P V+ EG + K K+ + PK + + KG G +D+S
Sbjct: 1160 PKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKG---DVDVS 1216
Query: 993 IPQLSLDAHLP------------SGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVP 1040
+P++ + +P + VEV G D K P+ +PKF + G E E+
Sbjct: 1217 VPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDV 1276
Query: 1041 GV--AELEGKG------------WGWDGRVKMPKLKMPSFGLARGKEAEVQGDRASPGEK 1086
+ A+++ G G +G++K PK KMP K + D G K
Sbjct: 1277 NLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPK 1336
Query: 1087 AESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVS-TAGQVVTEGHDAGLRM 1145
+ V + +PEV EG + V + + G KV +A V G D L+M
Sbjct: 1337 LKGD-VDVSLPEV-------------EGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKM 1382
Query: 1146 PPLGISLPQVELTGF-GEAGTPGQQAQSTVPSAE-GTAGYRV--QVPQVTLSLPGAQVAG 1201
P + +P+ + GF GE G + +P A+ +G ++ +VP V + P A++ G
Sbjct: 1383 PK--VKMPKFSMPGFKGE----GPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKG 1436
Query: 1202 GELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL---GARARVGG 1258
+ + E K +++P + L + + + + +K P + G + +
Sbjct: 1437 PKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINA 1496
Query: 1259 EGAEEQPPGAERTFCLSLPDVELS-------PSGGNHAEYQVAEGE-GEAGHKLKVRLPR 1310
E P + L +P V++ G + + + + G +G K+ + +P
Sbjct: 1497 PDVEVHGP----DWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPD 1552
Query: 1311 FGLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEE---EEEEGSGEGA 1367
L A EG +G K K P + + S ++ +P + + + + EG +G
Sbjct: 1553 VNL-EAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGP 1611
Query: 1368 SGRRGRVRVRLPRVGLAAPSKASRGQEGD-AAPKSPVRE---KSPKFRFPRVSLSPKARS 1423
+ V+ P++ + G EG PK + E K+PK P V L K
Sbjct: 1612 -----EIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPK 1666
Query: 1424 GSGDQE 1429
GD +
Sbjct: 1667 VKGDMD 1672
Score = 223 bits (569), Expect = 8e-58
Identities = 390/1662 (23%), Positives = 690/1662 (41%), Gaps = 442/1662 (26%)
Query: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175
++KGP+ K+ ++NI++ K M L + DV+ S PK +G + + +
Sbjct: 2945 KLKGPKFKMPEMNIKA----PKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVD-I 2999
Query: 176 KGP-----VPAAPARR---RLQLPRLRVR------------EVAEEAQAARLAAAAPPPR 215
+GP VP + L++P++++ +V A L + P
Sbjct: 3000 RGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGP--- 3056
Query: 216 KAKVEAEVAAGARFTAPQVELVGPR--LPGAEVGVPQVSAPKA---APSAEAAGGFALHL 270
KV+ +V P+ +L GP+ +P + P++S P + G + L
Sbjct: 3057 --KVDIDVP-DVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSL 3113
Query: 271 PTLGLGAPAPPA-VEAPAVGIQVPQVELPALPSLPTLP-------TLPCLETREGAVSVV 322
P + P ++ P V I P V++ +P ++P + V V
Sbjct: 3114 PKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVN 3173
Query: 323 VPT--LDVAAPTVGVDLA---LPGAEVEARG---EAPEVALKMPRLSFPRF-----GARA 369
+P LDV+ P V VD+ + G + + +G + PE+ +K P++S P G +
Sbjct: 3174 LPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKM 3233
Query: 370 KEVAEAKVAKVS--------------------------PEARVKGPRLRMPTFGLSLLEP 403
K + +A V P+A++KGP+L+MP +++ P
Sbjct: 3234 KGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNM--P 3291
Query: 404 RPAAPEV-------------------VESKLKLPTIKMPSLGIGVSGPEVKVP---KGPE 441
+ + PE+ +E +K P++ + + VSGP++ + K
Sbjct: 3292 KISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSR 3351
Query: 442 VKLPK---------APEVKLP-KVPEAALP----EVRLPEVELP---KVSEMKLPKVPEM 484
KLPK PEV + K P+ + ++ P+VE+ K S+ K+P + +
Sbjct: 3352 FKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFL-SI 3410
Query: 485 AVPEVRLPEVEL----PKVS------------EMKLPKVPEMAVPEVRL--PEVQL---- 522
+ P+V +P+VEL PKV + K PKV ++ PEV L P+V +
Sbjct: 3411 SSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKV-DIKAPEVNLNAPDVDVHGPD 3469
Query: 523 --LKVSEMKLPKV---------PEMAV------------------PEVRL--PEVQLPKV 551
LK+ +MK+PK P++AV P++ + PE L K
Sbjct: 3470 WNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGL-KG 3528
Query: 552 SEMKLPEVSEVAVPEVRLPEVQLP-KVPEMKVP-EMKLPKVP-EMKLPEMKLPEVQLPKV 608
+ K+P+++ + P++ +P++ L K P++K ++ LPK+ ++K PE+ +++ PKV
Sbjct: 3529 PKFKMPDMN-IKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEV---DIKGPKV 3584
Query: 609 PEMAVP-DVHLPEVQLPKVPEMKLPEMKLP---------EVKLPKVP--------EMAVP 650
A DVH P+ L K+P++K+P+ +P +V LPK ++ VP
Sbjct: 3585 DINAPDVDVHGPDWHL-KMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVP 3643
Query: 651 DVHL--PEVQLPKVPEMKLPKMPEMAVPEVRLPEVQL----PKVSE---MKLPKV----- 696
DV++ P+ +L K P+ K+P+M + P++ +P+ L PK+ + LPKV
Sbjct: 3644 DVNIEGPDAKL-KGPKFKMPEM-NIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLK 3701
Query: 697 -PEMAVP----DVHLPEVQLP-KVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKV 750
PE+ + D+ P++ + + K P K+PE+ L K P++++PD+ L ++ PKV
Sbjct: 3702 GPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHL-KAPKISMPDIDL-NLKGPKV 3759
Query: 751 S---EIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMP 807
++ LP+M+ K PEV + + P+V + A + +G ++ KMPK+ MP
Sbjct: 3760 KGDVDVSLPKMEGDL-------KGPEVDI-KGPKVDINAPDVD-VQGPDWHLKMPKVKMP 3810
Query: 808 KLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGALGL 867
K G GE G +V V LP +V G P V++D+P
Sbjct: 3811 KFSMP-----GFKGE-GPDVD---VNLPKADLDVSG-----------PKVDIDVPDV--- 3847
Query: 868 QGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKP 927
+EGPE ++ F++P + I P++ +I+ L + KVK
Sbjct: 3848 -------------NIEGPE--GKLKGPKFKMPEMNIKAPKISMPDID---LNLKGPKVKG 3889
Query: 928 SSKFSLPK---------FGLSGPKVA--KAEAEGAGRATKLKVSKFAISLPKARVGAEAE 976
SLPK + GPKV + + G LK+ K I +PK +
Sbjct: 3890 DMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPK--IKMPKISMPG--- 3944
Query: 977 AKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVA-----GADLKFKGPRFALPKFGVRGR 1031
KG G P +D+++P+ LD P V+V G D K KGP+F +P+ ++
Sbjct: 3945 FKGEG-----PEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAP 3999
Query: 1032 DTEAAEL--------VPG--------------VAELEGKG------------WGWDGRVK 1057
+ V G E++ KG G D +K
Sbjct: 4000 KISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLK 4059
Query: 1058 MPKLKMPSFGL----ARGKEAEVQGDRAS------------------------PGEKAES 1089
MPK+KMP F + G E +V +A G K +
Sbjct: 4060 MPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKM 4119
Query: 1090 TAVQLK-----IPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAG-QVVTEGHDAGL 1143
+ LK +PEV+L G + +G + ++ L G +V G +V + D +
Sbjct: 4120 PDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDV 4179
Query: 1144 RMPPLGISLPQVELTGFGEAGTPGQ--QAQSTVPSAE-GTAGYRV--QVPQVTLSLPGAQ 1198
+ P + +P+V++ F G G+ +P A+ +G +V VP V + P A+
Sbjct: 4180 QGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAK 4239
Query: 1199 VAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL-----GAR 1253
+ G + + E K P +++P +L + + +G + + LP + G
Sbjct: 4240 LKGPKFKMPEMNIKAPKISMPDFDLHL---------KGPKVKGDVDVSLPKVEGDLKGPE 4290
Query: 1254 ARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGL 1313
+ G + P + + PD L ++ + +GE G + V LP+ +
Sbjct: 4291 VDIKGPKVDIDAPDVD----VHGPDWHLKMPKVKMPKFSMPGFKGE-GPDVDVTLPKADI 4345
Query: 1314 --------VRAKEGAEEG--EKAKSPKLRLPRVGFSQSEM--------VTGEGSPSPEEE 1355
+ A + + EG K K PK ++P + ++ + G +
Sbjct: 4346 EISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDV 4405
Query: 1356 EEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRV 1415
+ EG +G + ++ P + + P G EG + K PKF+ P +
Sbjct: 4406 SLPKVEGDLKGP-----EIDIKGPSLDIDTPDVNIEGPEG--------KLKGPKFKMPEM 4452
Query: 1416 SL-SPKARSG------SGDQEEGGLRVRLPSVGFSETGAPGP 1450
++ +PK G + +G + V LP V E+ GP
Sbjct: 4453 NIKAPKISMPDFDLHLKGPKVKGDVDVSLPKV---ESDLKGP 4491
Score = 180 bits (456), Expect = 1e-44
Identities = 336/1396 (24%), Positives = 576/1396 (41%), Gaps = 289/1396 (20%)
Query: 155 DVEFSFPKFSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPP 214
DV+ + PK G K + V +L+ P+ ++ E++ +A +
Sbjct: 4671 DVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNL 4730
Query: 215 RKAKVEAEVAAGARFTAPQVE--LVGPRL----PGAEVGVPQVSA---------PKAAPS 259
+ KV+ +V T P+VE L GP P ++ P V PK
Sbjct: 4731 KGPKVKGDVDV----TLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMP 4786
Query: 260 AEAAGGFALHLPTLGLGAP-APPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGA 318
+ GF P + + P A V P V + +P V + + P E A
Sbjct: 4787 KFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKA 4846
Query: 319 VSVVVPT--LDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRLSFPRFGARAKEVAEAK 376
+ +P LD+ P V D + +VE + PEV LK PRL F
Sbjct: 4847 PKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFE------------- 4893
Query: 377 VAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKV 436
P+A++ GP L+MP+ L + P+ AP+ V+ LK P IG SGP++
Sbjct: 4894 ----GPDAKLSGPSLKMPS--LEISAPKVTAPD-VDLHLKAPK-------IGFSGPKL-- 4937
Query: 437 PKGPEVKLPKAPEVKLPKV------PEAAL--PEVRLPEVELPKV--------SEMKLPK 480
+G EV L K P+V+ P + P+ + P+V++P+ + PK +++K P
Sbjct: 4938 -EGGEVDL-KGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPS 4995
Query: 481 VPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRL--PEVQLLKVS-EMKLP------ 531
+ ++ VPE L +E P++S K + +P++ + P+++ K ++ +P
Sbjct: 4996 L-DVTVPEAEL-NLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDA 5053
Query: 532 --KVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPK 589
K P++ V + P+ L KV ++K P+ + ++ P+V+ ++K P+ K
Sbjct: 5054 SLKAPDVDV-NIAGPDAAL-KV-DVKSPKTKKTMFGKMYFPDVEF----DIKSPKFK--- 5103
Query: 590 VPEMKLPEMKLP-EVQLPKVPEMAVPDVHLPEVQL-PKVPEMKLPEMKLP------EVKL 641
E LP KL E+Q P + E+++P +H+ + + K P++K+P++ + ++K
Sbjct: 5104 -AEAPLPSPKLEGELQAPDL-ELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKG 5161
Query: 642 PKV-PEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMA 700
PKV + PD+++ + ++K P ++ P+V +P+V + +K PK+ +
Sbjct: 5162 PKVQANLGAPDINIEGLD----AKVKTPSF-GISAPQVSIPDVNV----NLKGPKI-KGD 5211
Query: 701 VPDVHL--PEVQLP-KVCEMKVPDMKLPEIKLPKVP-EMAVPDVHLPEVQLPKV-SEIRL 755
VP V L P+V L ++K P +P+I +P V E +VH QLP + ++R
Sbjct: 5212 VPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVH---AQLPSLEGDLRG 5268
Query: 756 PEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLG-RAES 814
P++++ + PDV L K P V LP MPK++ P L +
Sbjct: 5269 PDVKL-EGPDVSL-KGPGVDLP------------------SVNLSMPKVSGPDLDLNLKG 5308
Query: 815 PSRGKPGEAGAEVSGKLVTLPCLQ-PEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPA 873
PS G+ A V V P L V G+ VG + +P ++ +G P
Sbjct: 5309 PS--LKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVG----APD 5362
Query: 874 AKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSL 933
+ +G ++G +G + P V + P L ++E EG +++ K L
Sbjct: 5363 VTL-RGPSLQGDLAVSG----DIKCPKVSVGAPDL-SLEASEGSIKL--------PKMKL 5408
Query: 934 PKFGLS-----------GPKVAKAEAEGAGRATKLKVSK-------FAISLPKAR--VGA 973
P+FG+S GP+V+ E +G G LK + F + PK + +GA
Sbjct: 5409 PQFGISTPGSDLHVNAKGPQVS-GELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGA 5467
Query: 974 EAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDT 1033
E KG G LP + + L+ +L ++ +G D+ G LP + G +
Sbjct: 5468 TGEIKGPTVGGGLPGIGVQ----GLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEI 5523
Query: 1034 EAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKE---AEVQGDRASPGEKAES- 1089
+ L+G G+ G +K P+F +A + ++G + G
Sbjct: 5524 KGG--------LKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGG 5575
Query: 1090 -TAVQLKIPEVELVTLGAQEEGRA---------EGAVAVSGMQLSGLKVSTAGQVVTEGH 1139
+A + + E L G+ E + + + G+ SG KV +G
Sbjct: 5576 VSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGG----VKGG 5631
Query: 1140 DAGLRMPPLGISLPQVEL-TGFGEAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQ 1198
GL+ P L +S PQ L +G G+ P ++++P+ T S G +
Sbjct: 5632 QIGLQAPGLSVSGPQGHLESGSGKVTFP-----------------KMKIPKFTFS--GRE 5672
Query: 1199 VAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRL-----KLPTLGAR 1253
+ G E+ V V P+ E + +A AG+ E ++L K+P
Sbjct: 5673 LVGREMGV--------DVHFPKAEASI----QAGAGDGEWEESEVKLKKSKIKMPKFNFS 5720
Query: 1254 ARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEG--EGEAGHKLKVRLPRF 1311
G G P+ +S S G+ + + G EGEA + +F
Sbjct: 5721 KPKGKGGV------------TGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKF 5768
Query: 1312 GLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEG-SGEGASGR 1370
L K+K P+ R FS +G +P+ E E E G G+
Sbjct: 5769 SLF----------KSKKPRHR--SNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGK 5816
Query: 1371 RGRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSL-SPKARSGSGDQE 1429
G+++ GL + SK G +++ K + VSL S K+R S
Sbjct: 5817 HGKLKFG-TFGGLGSKSKGHYEVTGS-------DDETGKLQGSGVSLASKKSRLSSSSSN 5868
Query: 1430 EGGLRV--RLPSVGFS 1443
+ G +V +LP V S
Sbjct: 5869 DSGNKVGIQLPEVELS 5884
Score = 60.8 bits (146), Expect = 9e-09
Identities = 91/390 (23%), Positives = 149/390 (38%), Gaps = 92/390 (23%)
Query: 115 YEIKGPRAKVAKLNIQSLSPVKKKKMVP--GALGVPADLAPVDVEFSFPKFSRLRRGLKA 172
+ I P+ + +N+ P K K VP G G DL + + FPKFS
Sbjct: 5187 FGISAPQVSIPDVNVNLKGP-KIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSM------- 5238
Query: 173 EAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEV-AAGARFTA 231
P++ + V E A + A P +E ++ +
Sbjct: 5239 ------------------PKIGIPGVKMEGGGAEVHAQLP-----SLEGDLRGPDVKLEG 5275
Query: 232 PQVELVGP--RLPGAEVGVPQVSAPK-----AAPSAE-----AAGGFALHLPTLGLGAPA 279
P V L GP LP + +P+VS P PS + + +H P L L
Sbjct: 5276 PDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSG-V 5334
Query: 280 PPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLAL 339
++ G++VP ++ ++V P + + P++ DLA+
Sbjct: 5335 GGKMQVGGDGVKVPGIDATT------------------KLNVGAPDVTLRGPSLQGDLAV 5376
Query: 340 PG---------AEVEARGEAPEVALKMPRLSFPRFGARAKEV---AEAKVAKVSPEAR-- 385
G + EA E ++K+P++ P+FG AK +VS E +
Sbjct: 5377 SGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGP 5436
Query: 386 -----VKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPE--VKVP- 437
+KGPR+ P +L P+ ++K PT+ GIGV G E +++P
Sbjct: 5437 GVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPG 5496
Query: 438 ---KGPEVKLPKAPEVKLPKVPEAALPEVR 464
G +V LP VKLP + + PE++
Sbjct: 5497 IKSSGCDVNLP-GVNVKLP-TGQISGPEIK 5524
>gi|13491172 periaxin isoform 1 [Homo sapiens]
Length = 147
Score = 249 bits (636), Expect = 1e-65
Identities = 134/150 (89%), Positives = 137/150 (91%), Gaps = 8/150 (5%)
Query: 1 MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ 60
MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ
Sbjct: 1 MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ 60
Query: 61 EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP 120
EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP
Sbjct: 61 EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP 120
Query: 121 RAKVAKLNIQSLSPVKKKKMVPGALGVPAD 150
RAKVAKL ++ LSP AL P+D
Sbjct: 121 RAKVAKL-VRVLSPAP-------ALDCPSD 142
>gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]
Length = 5795
Score = 208 bits (529), Expect = 3e-53
Identities = 379/1528 (24%), Positives = 641/1528 (41%), Gaps = 344/1528 (22%)
Query: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175
++KGP+ V + P K+ A V L+ ++V+ P+ L+ +
Sbjct: 1590 DLKGPQIDVKGPKLDLKGP----KVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLS 1645
Query: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVE 235
+ ++P+ ++ A + A+ + KVEA+V+ + +
Sbjct: 1646 LADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVS-EPKVEADVSLPSMQGDLKTT 1704
Query: 236 LVGPRLPGA--EVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVP 293
+ + P A EV QV+ GF HLP + + P+++ P V ++ P
Sbjct: 1705 DLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQM-----PSLKMPKVALKGP 1759
Query: 294 QVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEA---RGE- 349
Q+++ P L+ + V+ P ++V+ P+V VD+ PGA++++ G+
Sbjct: 1760 QMDVKG----------PKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDL 1809
Query: 350 --------APEVALKMPRLSFPRFGARAK-EVAEAKVAKVSP--EARVKGPRLRMPTFGL 398
A + KMP+ P FG A + EA V +P EA V P ++
Sbjct: 1810 SLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLPSMQGDLKTT 1869
Query: 399 SLLEPRPAAPEVVES---KLKLPTIKMPSLGIGVSG-------PEVKVPK----GPEVKL 444
L P P+A VV++ +KLP ++P G G+ G P K+PK GP+ +
Sbjct: 1870 DLCIPLPSADLVVQAGQVDMKLPEGQVPE-GAGLKGHLPKVDMPSFKMPKVDLKGPQTDV 1928
Query: 445 PKAP-EVKLPKVPEAALP--EVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELP-KVS 500
A ++K PK E P EV LP +E+ V K ++ L + ++ K S
Sbjct: 1929 KGAKLDLKGPKA-EVTAPDVEVSLPSMEVD-VQAQKAKLDGARLEGDLSLADKDMTAKDS 1986
Query: 501 EMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLP-KVSEMKL-PE 558
+ K+PK +M V P + ++ PKV +V LP +Q K +++ + P
Sbjct: 1987 KFKMPKF-KMPSFGVSAPGRSIEASVDVPAPKVEA----DVSLPSMQGDLKTTDLSIQPP 2041
Query: 559 VSEVAVP----EVRLPEVQLPK-------VPEMKVPEMKLPKVPEMKLPEMKL--PEVQL 605
+++ V +V+LPE +P+ +P++++P +K+PKV ++K P++ + P++ L
Sbjct: 2042 SADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKV-DLKGPQVDIKGPKLDL 2100
Query: 606 --PKVPEMAVPDVHLPEVQLPKVP-EMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKV 662
PKV EM VPDV EV LP + +++ P KL L +A D+ + + K+
Sbjct: 2101 KDPKV-EMRVPDV---EVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKF-KM 2155
Query: 663 PEMKLPKMPEMAVPEVRLP---EVQLPKV-SEMKLP------KVPEMAVP---------- 702
P+ K+P ++ P + +V PKV ++M LP K ++++
Sbjct: 2156 PKFKMPSFG-VSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQA 2214
Query: 703 ---DVHLPEVQLPKVCEMK--VPDMKLPEIKLPKVPEMAVPDVHL--PEVQL--PKVSEI 753
DV L E +P+ +K +P +++P K+PKV ++ P++ + P++ L PKV E+
Sbjct: 2215 GQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKV-DLKGPEIDIKGPKLDLKDPKV-EV 2272
Query: 754 RLPEMQVPKVPDVHLP-KAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRA 812
P+++V +P V + KAP KL A + + + FKMPK M G +
Sbjct: 2273 TAPDVEV-SLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVS 2331
Query: 813 ESPSRGKPGEAGAEVSGKLV----TLPCLQ------------PEVDGEAHVGVPSLTLPS 856
+ GK EA A+VS V +LP +Q P D E G + LP
Sbjct: 2332 ---ALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLP- 2387
Query: 857 VELDLPGALGLQG-----QVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQL--- 908
E +P GL+G Q+P+ KM K + ++GP++ ++ + P +++ P +
Sbjct: 2388 -EGPVPEGAGLKGHLPKLQMPSFKMPKVD-LKGPQIDVKGPKLDLKGPKTDVMAPDVEVS 2445
Query: 909 -PAVEIE-------------EGRLEMIETKVKPSS------KFSLPKFGLSGPKVAKAEA 948
P+VE++ EG L + + V KF +P FG+S P
Sbjct: 2446 QPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAP------- 2498
Query: 949 EGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVE 1008
G++ + V +S PK EA+ + G L A DLSI S D + +G+V+
Sbjct: 2499 ---GKSIEASVD---VSAPKV----EADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVD 2548
Query: 1009 VAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGL 1068
V + GP VP A L+G +PK++MPSF +
Sbjct: 2549 VKLPE----GP-------------------VPEGAGLKGH---------LPKVQMPSFKM 2576
Query: 1069 ----ARGKEAEVQGDRAS-PGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQL 1123
+G + +V+G + G KAE TA P+VE+ +L + E + G +L
Sbjct: 2577 PEMDLKGPQLDVKGPKLDLKGPKAEVTA-----PDVEM-SLSSMEVDVQAPRAKLDGARL 2630
Query: 1124 SGLKVSTAGQVVTEGHD----AGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEG 1179
G +S A + VT +MP +S P + + +A ++PS +G
Sbjct: 2631 EG-DLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQG 2689
Query: 1180 ------------TAGYRVQVPQVTLSLPGAQVAGGELLVGE-GVFKMPTVTVPQLELDVG 1226
+A VQ QV + LP V G L G +MP+ +P+++L
Sbjct: 2690 DLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLK-- 2747
Query: 1227 LSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGG 1286
G + V G + + P AE ++ PDV++S S
Sbjct: 2748 ------------------------GPQIDVKGPNVDLKGPKAE----VTAPDVKMSLS-- 2777
Query: 1287 NHAEYQVAEGEGEAGHKLKVRLPRFGLVRAK-EG----AEEGEKAKSPKLRLPRV---GF 1338
++ V+ PR L A+ EG A++G AK K ++P+ F
Sbjct: 2778 --------------SMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSF 2823
Query: 1339 SQSEMVTGEGSPSPEEEEEEEEEGSGEGASG--RRGRVRVRLPRVGLAAPSKASRGQEGD 1396
S + E + E +GS G + +R++ P +A + GQ
Sbjct: 2824 GVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPP----SAQLEVQAGQVDV 2879
Query: 1397 AAPKSPVRE-----------KSPKFRFPRVSL---------------SPKARSGSGDQEE 1430
P+ V E + P F+ P+V L PKA + D E
Sbjct: 2880 KLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVE- 2938
Query: 1431 GGLRVRLPSVGFSETGAPGP-ARMEGAQ 1457
V LPSV E P A+++GA+
Sbjct: 2939 ----VSLPSV---EVDVEAPRAKLDGAR 2959
Score = 207 bits (526), Expect = 8e-53
Identities = 383/1545 (24%), Positives = 630/1545 (40%), Gaps = 346/1545 (22%)
Query: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175
++KGP+ + + P K + VP V L ++V+ P+ L+ +
Sbjct: 2085 DLKGPQVDIKGPKLDLKDP-KVEMRVPD---VEVSLPSMEVDVQAPRAKLDSAHLQGDLT 2140
Query: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAP--PPRKAKVEAEVAAGA-RFTAP 232
+ ++P+ ++ A + A+ PP KVEA+++ + +
Sbjct: 2141 LANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSPP---KVEADMSLPSMQGDLK 2197
Query: 233 QVEL-VGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQ 291
+L + P +V QV G HLP L + P+ + P V ++
Sbjct: 2198 TTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQM-----PSFKVPKVDLK 2252
Query: 292 VPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAP 351
P++++ P L+ ++ V V P ++V+ P+V VD+ PGA+++
Sbjct: 2253 GPEIDIKG----------PKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLD------ 2296
Query: 352 EVALKMPRLSFPRFGARAK-EVAEAKVAKVSPEARVKGPRLRMPTFGLSLL-EPRPAAPE 409
GAR + +++ A + +++ K P+ +M +FG+S L + A+ +
Sbjct: 2297 --------------GARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASAD 2342
Query: 410 V----VESKLKLPT----IKMPSLGIGVSGPEVKVPKGP-EVKLPKAPEVKLPKVPEAAL 460
V VE+ + LP+ +K L + +++V G +VKLP+ P VPE A
Sbjct: 2343 VSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGP------VPEGAG 2396
Query: 461 PEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVP-EVRLPE 519
+ LP++++P K+PKV ++ P++ +V+ PK+ ++K PK MA EV P
Sbjct: 2397 LKGHLPKLQMPS---FKMPKV-DLKGPQI---DVKGPKL-DLKGPKTDVMAPDVEVSQPS 2448
Query: 520 VQL-----------------LKVSEMKLP-KVPEMAVPEVRLPEVQLPKVSEMKLPEVSE 561
V++ L V++ + K +P+ ++P + + V +
Sbjct: 2449 VEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASV-D 2507
Query: 562 VAVPEVRLPEVQLPKVPEMKVPEMKL-PKVPEMKLPEMKLPEVQLPK--VPEMAVPDVHL 618
V+ P+V ++K ++ + P ++++ ++ +V+LP+ VPE A HL
Sbjct: 2508 VSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQV-DVKLPEGPVPEGAGLKGHL 2566
Query: 619 PEVQLP--KVPEMKLPEMKLPEVKLPKVP------EMAVPDVHLP------EVQLPKVP- 663
P+VQ+P K+PEM L +L +VK PK+ E+ PDV + +VQ P+
Sbjct: 2567 PKVQMPSFKMPEMDLKGPQL-DVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKL 2625
Query: 664 -------EMKLP-----------KMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVP-DV 704
++ L KMP+ +P R V P S L V E+ V D+
Sbjct: 2626 DGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFR---VSAPGESIEALVDVSELKVEADM 2682
Query: 705 HLPEVQ----------LPKVCEMKVP----DMKLPEIKLPKVPEMAVPDVHLPEVQLP-- 748
LP +Q P +++V D+KLPE VPE A HLP++Q+P
Sbjct: 2683 SLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPE---GHVPEGAGLKGHLPKLQMPSF 2739
Query: 749 KVSEIRLPEMQVP-KVPDVHL--PKA----PEVKLP--------RAPEVQLKATKAE--- 790
K+ E+ L Q+ K P+V L PKA P+VK+ +AP +L + E
Sbjct: 2740 KMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDL 2799
Query: 791 --QAEGM---EFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEA 845
+GM + FKMPK MP G + + GK EA +VS V P + G+
Sbjct: 2800 SLADKGMTAKDSKFKMPKFKMPSFGVS---APGKSIEASVDVSELKVEADGSFPSMQGDL 2856
Query: 846 HVGVPSLTLPSVELDL--------------PGALGLQG-----QVPAAKMGKGERVEGPE 886
+ PS +L++ P GL+G Q+P+ KM K + ++GP+
Sbjct: 2857 KTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVD-LKGPQ 2915
Query: 887 VAAGVREVGFRVPSVEIVTPQ----LPAVEIE-------------EGRLEMIETKVKPSS 929
+ ++ + P E+ P LP+VE++ EG L + + V
Sbjct: 2916 IDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKD 2975
Query: 930 ------KFSLPKFGLSGP----------KVAKAEAEGAGRATK--LKVSKFAISLPKARV 971
KF +P FG+S P K EAE + + + LK + +I P A++
Sbjct: 2976 SKFKMPKFKMPSFGVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQL 3035
Query: 972 GAEAEA-----------KGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPR 1020
+A +GAG G LP L + P + KV+ G + KGP+
Sbjct: 3036 EVQAGQVDLKLPEGHVPEGAGLKGHLPKLQM--PSFKMP------KVDRKGPQIDVKGPK 3087
Query: 1021 FAL--PKFGVRGRDTEAAELVPGV-AELEGKGWGWDG-------------------RVKM 1058
L PK V D E ++ PG+ ++E G DG + KM
Sbjct: 3088 LDLKGPKTDVTAPDVEVSQ--PGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKM 3145
Query: 1059 PKLKMPSFGL-ARGKEAEVQGDRASPGEKAE----STAVQLKIPEVELVTLGAQEEGRAE 1113
PK KMPSFG+ A GK EV D ++P +A+ S LK ++ + AQ E +A
Sbjct: 3146 PKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQA- 3204
Query: 1114 GAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISL-----PQVELTGFGEAGTPGQ 1168
G V V + G + AG +GH L+MP + PQ+++ G + G
Sbjct: 3205 GQVDVKLPE--GHVLEGAG---LKGHLPKLQMPSFKMPKVDRKGPQIDIKG-PKLDLKGP 3258
Query: 1169 QAQSTVPSAE-GTAGYRVQVPQVTLSLPGAQVAGGELLVGEGV------FKMPTVTVPQL 1221
+ T P E V V L GA++ G L + V FKMP +P
Sbjct: 3259 KMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSY 3318
Query: 1222 ELDV-GLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVE 1280
G S +A +A + + LP++ + + LP V+
Sbjct: 3319 RASAPGKSIQASVDVSAP-KAEADVSLPSMQGDLKT-------------TDLSIQLPSVD 3364
Query: 1281 LSPSGGNH----AEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRV 1336
L G E V EG G GH KV +P F + + + + + K PKL L
Sbjct: 3365 LEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVD-IKGPKLDLK-- 3421
Query: 1337 GFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGD 1396
++E+ + S E V V+ PR L EGD
Sbjct: 3422 -VPKAEVTVPDVEVSLPSVE-----------------VDVQAPRAKLDGARL-----EGD 3458
Query: 1397 AA-PKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
+ + V K KF+ P+ + S G E L V P V
Sbjct: 3459 LSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKV 3503
Score = 205 bits (521), Expect = 3e-52
Identities = 365/1441 (25%), Positives = 593/1441 (41%), Gaps = 342/1441 (23%)
Query: 116 EIKGPRAKVAKLNIQ-SLSPVKKKKMVPGA------LGVPADLAPVDVEFSFPKFSRLRR 168
++KG +A+V + SL V+ PGA L LA DV KF +
Sbjct: 1274 DLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKF 1333
Query: 169 GLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGAR 228
+ + V P + A L P++ +++ + L + + E+ AG
Sbjct: 1334 KMPSFGVSAPGKSIEASVDLSAPKVEA-DMSLPSMQGDLKTTDLSIQPPSTDLELQAGQ- 1391
Query: 229 FTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAV 288
+V +P+ P+ A G HLP L + P+ + P V
Sbjct: 1392 ---------------LDVKLPEGPVPEGA-------GLKGHLPKLQM-----PSFKVPKV 1424
Query: 289 GIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARG 348
++ P++++ P L+ ++ V V P ++V+ P+V VD+ PGA+++
Sbjct: 1425 DLKGPEIDIKG----------PKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDG-- 1472
Query: 349 EAPEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSL------LE 402
G ++++ A + +++ K P+ +MP+FG+S
Sbjct: 1473 -----------------GRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEAS 1515
Query: 403 PRPAAPEVVESKLKLPT----IKMPSLGIGVSGPEVKVPKGP-EVKLPKAPEVKLPKVPE 457
+AP+ VE+ + LP+ +K L I +++V G +VKLP+ P V +
Sbjct: 1516 VDVSAPK-VEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP-VSEGAGLK 1573
Query: 458 AALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRL--PEVEL--PKVSEMKLPKVPEMAVP 513
LP+V++P ++PKV ++K P++ ++ P++ L P+VE+ P V ++ P
Sbjct: 1574 GHLPKVQMPSFKMPKV-DLKGPQI-DVKGPKLDLKGPKVEVTAPDVKMSLSSMEVDVQAP 1631
Query: 514 EVRLPEVQL------------LKVSEMKLP--KVPEMAV---------------PEVRLP 544
+L QL K S+ K+P K+P V P+V
Sbjct: 1632 RAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVE-A 1690
Query: 545 EVQLPKV-SEMKLPEVS----------EVAVPEVRLPEVQLPK-------VPEMKVPEMK 586
+V LP + ++K ++S + V+LPE LP+ +P++++P +K
Sbjct: 1691 DVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLK 1750
Query: 587 LPKVPEMKLPEM--KLPEVQL--PKVPEMAVPDVHLPEVQLPKVP-EMKLPEMKLPEVKL 641
+PKV +K P+M K P++ L PK MA PDV EV LP V +++ P KL V+L
Sbjct: 1751 MPKV-ALKGPQMDVKGPKLDLKGPKAEVMA-PDV---EVSLPSVEVDVEAPGAKLDSVRL 1805
Query: 642 PKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLP---EVQLPKV-SEMKLPKVP 697
+A DV + + K+P+ K+P ++ P + +V PKV +E+ LP +
Sbjct: 1806 EGDLSLADKDVTAKDSKF-KMPKFKMPSF-GVSAPGKSIEASVDVSAPKVEAEVSLPSMQ 1863
Query: 698 -EMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMA--VPDVHLPEVQLPKVSEIR 754
++ D+ +P V + DMKLPE ++P+ + +P V +P ++PKV +++
Sbjct: 1864 GDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKV-DLK 1922
Query: 755 LPEMQVPKVP-DVHLPKAP------EVKLPRAPEVQLKATKAE----QAEG--------- 794
P+ V D+ PKA EV LP + EV ++A KA+ + EG
Sbjct: 1923 GPQTDVKGAKLDLKGPKAEVTAPDVEVSLP-SMEVDVQAQKAKLDGARLEGDLSLADKDM 1981
Query: 795 --MEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSL 852
+ FKMPK MP G + + G+ EA +V V P + G+ S+
Sbjct: 1982 TAKDSKFKMPKFKMPSFGVS---APGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSI 2038
Query: 853 TLPSVEL--------------DLPGALGLQGQVPAAKMG---------KGERVE--GPEV 887
PS +L +P GL+G +P +M KG +V+ GP++
Sbjct: 2039 QPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKL 2098
Query: 888 AAGVREVGFRVPSVEIVTP------QLPAVEIEEGRLEMIETKVK-----PSSKFSLPKF 936
+V RVP VE+ P Q P +++ L+ T SKF +PKF
Sbjct: 2099 DLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKF 2158
Query: 937 GLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQL 996
K+ G++ + V +S PK EA+ G L DLSI L
Sbjct: 2159 -----KMPSFGVSAPGKSIEASVD---VSPPK----VEADMSLPSMQGDLKTTDLSIQPL 2206
Query: 997 SLD------------------------AHLPS--------GKVEVAGADLKFKGPRFAL- 1023
S D HLP KV++ G ++ KGP+ L
Sbjct: 2207 SADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLK 2266
Query: 1024 -PKFGVRGRDTEAA-------ELVPGV----AELEG-------KGWGWDGRVKMPKLKMP 1064
PK V D E + PG A LEG D + KMPK KM
Sbjct: 2267 DPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKML 2326
Query: 1065 SFGL-ARGKEAEVQGDRASPGEKAE-----------STAVQLKIPEVEL-VTLGAQEEGR 1111
SFG+ A GK E D ++ +A+ +T + ++ P +L V G +
Sbjct: 2327 SFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKL 2386
Query: 1112 AEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQ 1171
EG V + +GLK GH L+MP +P+V+L G + G +
Sbjct: 2387 PEGPVP----EGAGLK----------GHLPKLQMP--SFKMPKVDLKG-PQIDVKGPKLD 2429
Query: 1172 STVPSAEGTA-GYRVQVP--QVTLSLPGAQVAG----GELLVG-------EGVFKMPTVT 1217
P + A V P +V + PGA++ G G+L V + FK+P
Sbjct: 2430 LKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFK 2489
Query: 1218 VPQLELDV-GLSREAQAGEAATGEGGLRLKLPTLGARARVGGE----GAEEQPPGAERTF 1272
+P + G S EA +A K+ G+ + + G+ QPP A+
Sbjct: 2490 MPSFGVSAPGKSIEASVDVSAP-------KVEADGSLSSMQGDLKATDLSIQPPSADLEV 2542
Query: 1273 CLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLR 1332
DV+L P G V EG G GH KV++P F + + + K PKL
Sbjct: 2543 QAGQVDVKL-PEG------PVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLD-VKGPKLD 2594
Query: 1333 L 1333
L
Sbjct: 2595 L 2595
Score = 202 bits (515), Expect = 1e-51
Identities = 371/1533 (24%), Positives = 618/1533 (40%), Gaps = 336/1533 (21%)
Query: 116 EIKGPRAKVAKLNIQ-SLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEA 174
++KGP+A+V +++ SLS ++ P A D A ++ + S +G+ A+
Sbjct: 2594 DLKGPKAEVTAPDVEMSLSSMEVDVQAPRA---KLDGARLEGDLSLAD-----KGVTAKD 2645
Query: 175 VKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQV 234
K +P + ++P RV E +A + + KVEA+++ + +
Sbjct: 2646 SKFKMP------KFKMPSFRVSAPGESIEALVDVS------ELKVEADMSLPSMQGDLKT 2693
Query: 235 ELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFAL--HLPTLGLGAPAPPAVEAPAVGIQV 292
+ + P A++ V P G L HLP L + P+ + P V ++
Sbjct: 2694 TDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQM-----PSFKMPEVDLKG 2748
Query: 293 PQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVE-ARGE-- 349
PQ+++ P ++ + V P + ++ ++ VD+ P A+++ AR E
Sbjct: 2749 PQIDVKG----------PNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGD 2798
Query: 350 ---------APEVALKMPRLSFPRFGARAK--------EVAEAKVAKVSPEARVKGP--- 389
A + KMP+ P FG A +V+E KV ++G
Sbjct: 2799 LSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKT 2858
Query: 390 ---RLRMPTFGLSLLE-------PRPAAPEVVESKLKLPTIKMPSLG---IGVSGPEVKV 436
R++ P+ L + P PE K LP ++MPS + + GP++ V
Sbjct: 2859 TDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDV 2918
Query: 437 PKGPEVKL--PKAPEVKLPKVPEAALPEVRLPEVELP--KVSEMKLPKVPEMAVPEVRLP 492
KGP++ L PKA EV P V E +LP V + +VE P K+ +L +A +V
Sbjct: 2919 -KGPKLDLKGPKA-EVTAPDV-EVSLPSVEV-DVEAPRAKLDGARLEGDLSLADKDVTA- 2973
Query: 493 EVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVS 552
K S+ K+PK +M V P + ++ PKV EV LP +Q
Sbjct: 2974 -----KDSKFKMPKF-KMPSFGVSAPGKSIEVSVDVSAPKVEA----EVSLPSMQ----G 3019
Query: 553 EMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMK--LPEMKLPEVQLPKV-- 608
++K ++S + P +L EVQ +V ++K+PE +P+ +K LP++++P ++PKV
Sbjct: 3020 DLKTTDIS-IEPPSAQL-EVQAGQV-DLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDR 3076
Query: 609 --PEMAVP-----------DVHLPEVQLPKVP---EMKLPEMKLPEVKLPKVPEMAVPDV 652
P++ V DV P+V++ + +++ P KL +L +A DV
Sbjct: 3077 KGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDV 3136
Query: 653 HLPEVQLPKVPEMKLPKMPEMAVPEVR--LPEVQLPKV-SEMKLPKVP------------ 697
+ + K+P+ K+P A + L +V PKV +++ LP +
Sbjct: 3137 TAKDSKF-KMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEP 3195
Query: 698 -------EMAVPDVHLPEVQLPKVCEMK--VPDMKLPEIKLPKVPEMAVPDVHLPEVQLP 748
+ DV LPE + + +K +P +++P K+PKV P + +++ P
Sbjct: 3196 PSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKG-PQI---DIKGP 3251
Query: 749 KVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAE--------QAEGMEFGFK 800
K+ +++ P+M V PDV + + AP +L + E + FK
Sbjct: 3252 KL-DLKGPKMDVT-APDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFK 3309
Query: 801 MPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELD 860
MPK MP RA +P GK +A +VS P + G+ S+ LPSV+L+
Sbjct: 3310 MPKFKMPSY-RASAP--GKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLE 3366
Query: 861 L--------------PGALGLQGQVPAAKMGKGER----VEGPEVAAGVREVGFRVPSVE 902
+ P GL+G +P +M + ++ P+V ++ +VP E
Sbjct: 3367 VQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAE 3426
Query: 903 IVTPQ----LPAVEIE-------------EGRLEMIETKVKPSS------KFSLPKFGLS 939
+ P LP+VE++ EG L + E V KF +P FG+S
Sbjct: 3427 VTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVS 3486
Query: 940 GP-----------------KVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEA----- 977
P V+ + +G +AT L + + L V + E
Sbjct: 3487 APGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPV 3546
Query: 978 -KGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFAL--PKFGVRGRDTE 1034
+GAG G LP +++ L + KV++ G + KGP+ L PK VR D E
Sbjct: 3547 PEGAGLKGHLPKVEMP--------SLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVE 3598
Query: 1035 AAELVPGV-------------AELEGK-------GWGWDGRVKMPKLKMPSFGL-ARGKE 1073
+ +P V LEG D + KMPK KMPSF + A GK
Sbjct: 3599 VS--LPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKS 3656
Query: 1074 AEVQGDRASPGEKAE-----------STAVQLKIPEVEL-VTLGAQEEGRAEGAVAVSGM 1121
E D ++P +A+ +T + ++ P +L V G + EG V
Sbjct: 3657 MEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEG-- 3714
Query: 1122 QLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAE-GT 1180
+GLK + + + L+MP + + PQV++ G + +A+ T P E
Sbjct: 3715 --AGLK-----EHLPKVEMPSLKMPKVDLKGPQVDIKG-PKLDLKVSKAEVTAPDVEVSL 3766
Query: 1181 AGYRVQVPQVTLSLPGAQVAGGELLVGEGV------FKMPTVTVPQLELDVGLSREAQAG 1234
V V L AQ+ G L + V FKMP +P G+S ++
Sbjct: 3767 PSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSF----GVSAPGKSI 3822
Query: 1235 EAATGEGGLRLK----LPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAE 1290
EA+ +++ LP++ + QP A+ T D++L E
Sbjct: 3823 EASVHVSAPKVEADVSLPSMQGDLKT--TDLSIQPHSADLTVQARQVDMKL-------LE 3873
Query: 1291 YQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRL--PRVGFSQSEMVTGEG 1348
V E G GH KV++P F + + E + K PKL L P+V + ++
Sbjct: 3874 GHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEID-IKGPKLDLKDPKVEVTAPDVEVSLP 3932
Query: 1349 SPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAA-PKSPVREKS 1407
S E + E G G R EGD + + K
Sbjct: 3933 SV------EVDVEAPGAKLDGAR---------------------LEGDLSLADKDMTAKD 3965
Query: 1408 PKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
KF+ P+ + S G E + V P V
Sbjct: 3966 SKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKV 3998
Score = 202 bits (514), Expect = 2e-51
Identities = 380/1531 (24%), Positives = 632/1531 (41%), Gaps = 364/1531 (23%)
Query: 116 EIKGPRAKVA-----------KLNIQSLSPVKKKKMVPGALGVP-ADLAPVDVEFSFPKF 163
++KGP+A+V ++++Q+ + G L + D+ D +F PKF
Sbjct: 944 DLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKF 1003
Query: 164 SRLRRGLKA--EAVKG--PVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKV 219
G+ A +++K V A L LP ++ + + L+ P KV
Sbjct: 1004 KMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQ-----GDLKTTDLSIQ-PASTDLKV 1057
Query: 220 EAEVAAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPA 279
+A+ +V +P+ P+ A G HLP + +
Sbjct: 1058 QADQV--------------------DVKLPEGHLPEGA-------GLKGHLPKVEM---- 1086
Query: 280 PPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLAL 339
P+ + P V ++ PQV++ P L+ + V P ++V+ P+V VD+
Sbjct: 1087 -PSFKMPKVALKGPQVDVKG----------PKLDLKSPKAEVTAPDVEVSLPSVEVDVEA 1135
Query: 340 PGAEVEA---RGE---------APEVALKMPRLSFPRFGARAK-EVAEAKVAKVSP--EA 384
PGA++++ GE A + KMP+ P FGA A + EA V +P EA
Sbjct: 1136 PGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEA 1195
Query: 385 RVKGPRLR--MPTFGLSLLEP----------------RPAAPEVVESKLKLPTIKMPSL- 425
V P ++ + T LS+ P PE K LP ++MPSL
Sbjct: 1196 DVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLK 1255
Query: 426 --GIGVSGPEVKVPKGPEVKLP-KAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVP 482
+ + GP+V+V +GP++ L EV +V V LP VE+
Sbjct: 1256 MPKVDLKGPQVEV-RGPKLDLKGHKAEVTAHEV------AVSLPSVEV------------ 1296
Query: 483 EMAVPEVRLPEVEL------------PKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKL 530
+M P +L +L K S+ K+PK +M V P + ++
Sbjct: 1297 DMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKF-KMPSFGVSAPGKSIEASVDLSA 1355
Query: 531 PKV-PEMAVPEVR--LPEVQL---PKVSEMKLPEVSEVAVPEVRLPEVQLPK-------V 577
PKV +M++P ++ L L P ++++L + +V+LPE +P+ +
Sbjct: 1356 PKVEADMSLPSMQGDLKTTDLSIQPPSTDLEL----QAGQLDVKLPEGPVPEGAGLKGHL 1411
Query: 578 PEMKVPEMKLPKVPEMKLPE--MKLPEVQL--PKVPEMAVPDVHLPEVQLPKVP-EMKLP 632
P++++P K+PKV ++K PE +K P++ L PKV E+ PDV EV LP V +++ P
Sbjct: 1412 PKLQMPSFKVPKV-DLKGPEIDIKGPKLDLKDPKV-EVTAPDV---EVSLPSVEVDVEAP 1466
Query: 633 EMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLP---EVQLPKV- 688
KL +L + +A D+ + + K+P+ K+P ++ P + +V PKV
Sbjct: 1467 GAKLDGGRLEEDMSLADKDLTTKDSKF-KMPKFKMPSF-GVSAPGKSIEASVDVSAPKVE 1524
Query: 689 SEMKLPKVP-EMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMA--VPDVHLPEV 745
+++ LP + ++ D+ + + D+KLPE + + + +P V +P
Sbjct: 1525 ADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSF 1584
Query: 746 QLPKVSEIRLPEMQV--PKVPDVHLPK----APEVKLP-RAPEVQLKATKAE----QAEG 794
++PKV +++ P++ V PK+ D+ PK AP+VK+ + EV ++A +A+ Q EG
Sbjct: 1585 KMPKV-DLKGPQIDVKGPKL-DLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEG 1642
Query: 795 -----------MEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKL----VTLPCLQ- 838
+ FKMPK MP G + + GK EA +VS V+LP +Q
Sbjct: 1643 DLSLADKAVTAKDSKFKMPKFKMPSFGVS---APGKSIEASVDVSEPKVEADVSLPSMQG 1699
Query: 839 -----------PEVDGEAHVGVPSLTLPSVELDLPGALGLQG-----QVPAAKMGKGERV 882
P D E G ++ LP E LP G +G Q+P+ KM K +
Sbjct: 1700 DLKTTDLSIQSPSADLEVQAGQVNVKLP--EGPLPEGAGFKGHLPKVQMPSLKMPK-VAL 1756
Query: 883 EGPEVAAGVREVGFRVPSVEIVTP----QLPAVEIE-------------EGRLEMIETKV 925
+GP++ ++ + P E++ P LP+VE++ EG L + + V
Sbjct: 1757 KGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDV 1816
Query: 926 -KPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAG 984
SKF +PKF K+ G++ + V +S PK EAE G
Sbjct: 1817 TAKDSKFKMPKF-----KMPSFGVSAPGKSIEASVD---VSAPK----VEAEVSLPSMQG 1864
Query: 985 LLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAE 1044
L DL IP LPS + V + K P +P
Sbjct: 1865 DLKTTDLCIP-------LPSADLVVQAGQVDMKLPEGQVP-------------------- 1897
Query: 1045 LEGKGW-GWDGRVKMPKLKMPSFGLARGKEAEVQGDRAS-PGEKAESTA--VQLKIPEVE 1100
EG G G +V MP KMP L +G + +V+G + G KAE TA V++ +P +E
Sbjct: 1898 -EGAGLKGHLPKVDMPSFKMPKVDL-KGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSME 1955
Query: 1101 LVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGF 1160
V + AQ + + +GA + L+ ++ ++ +MP G+S P +
Sbjct: 1956 -VDVQAQ-KAKLDGARLEGDLSLADKDMTAKD---SKFKMPKFKMPSFGVSAPGRSIEAS 2010
Query: 1161 GEAGTPGQQAQSTVPSAEG------------TAGYRVQVPQVTLSLPGAQVAGGELLVGE 1208
+ P +A ++PS +G +A +VQ QV + LP V G L G
Sbjct: 2011 VDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGH 2070
Query: 1209 GVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGA 1268
+P V +P L++ K+ G + + G + + P
Sbjct: 2071 ----LPKVEMPSLKMP---------------------KVDLKGPQVDIKGPKLDLKDPKV 2105
Query: 1269 ERTFCLSLPDVELS-PSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAK 1327
E + +PDVE+S PS + Q + ++ H L + K+ + K K
Sbjct: 2106 E----MRVPDVEVSLPS--MEVDVQAPRAKLDSAH-----LQGDLTLANKDLTTKDSKFK 2154
Query: 1328 SPKLRLPRVGFS-QSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAP 1386
PK ++P G S + + SP + E + S +G L L+A
Sbjct: 2155 MPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQG-----DLKTTDLSIQPLSAD 2209
Query: 1387 SKASRGQEGDAAPKSPVRE-----------KSPKFRFPRVSLSPKARSGSG---DQEEGG 1432
K GQ + PV E + P F+ P+V L G D ++
Sbjct: 2210 VKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPK 2269
Query: 1433 LRVRLPSVGFS------ETGAPGPARMEGAQ 1457
+ V P V S + APG A+++GA+
Sbjct: 2270 VEVTAPDVEVSLPSVEVDVKAPG-AKLDGAR 2299
Score = 201 bits (510), Expect = 6e-51
Identities = 362/1451 (24%), Positives = 579/1451 (39%), Gaps = 367/1451 (25%)
Query: 276 GAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGV 335
GA AP +V + P+VE + L L+T + +SV P+ D+ V
Sbjct: 686 GASAPGKSMEASVDVSAPKVEA----DVSLLSMQGDLKTTD--LSVQTPSADLEVQDGQV 739
Query: 336 DLALPGAEV----EARGEAPEV---ALKMPRLSF--PRF---GARAKEVA-EAKVAKVSP 382
D+ LP + +G P+V +LKMP++ P+ G +A+ A + K++ S
Sbjct: 740 DVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSM 799
Query: 383 EARVKGPRLRMPTF----GLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGP------ 432
E V+ PR ++ LSL + A + SK K+P KMPS G+ G
Sbjct: 800 EVDVQAPRAKLDGARLEGDLSLADKEVTAKD---SKFKMPKFKMPSFGVSAPGKSMEDSV 856
Query: 433 EVKVPK-----------------GPEVKLPKAP--------EVKLPK--VPEAALPEVRL 465
+V PK ++ P A +VKLP+ VPE A P+V L
Sbjct: 857 DVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHL 916
Query: 466 PEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVP--EVRLPEVQL- 522
P+VE+P K+PKV ++ P++ +V+ PK+ ++K PK E+ P EV LP +++
Sbjct: 917 PKVEMP---SFKMPKV-DLKGPQI---DVKGPKL-DLKGPKA-EVTAPDGEVSLPSMEVD 967
Query: 523 -------------------------LKVSEMKLP--KVPEMAVPE-----VRLPEVQLPK 550
K S+ K+P K+P V L +V PK
Sbjct: 968 VQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPK 1027
Query: 551 V-SEMKLPEVS-------------------EVAVPEVRLPEVQLPK-------VPEMKVP 583
V +++ LP + + +V+LPE LP+ +P++++P
Sbjct: 1028 VEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMP 1087
Query: 584 EMKLPKV----PEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVP-EMKLPEMKLPE 638
K+PKV P++ + KL +++ PK E+ PDV EV LP V +++ P KL
Sbjct: 1088 SFKMPKVALKGPQVDVKGPKL-DLKSPKA-EVTAPDV---EVSLPSVEVDVEAPGAKLDS 1142
Query: 639 VKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPE 698
+L +A DV + + K+P+ K+P A P + ++ PKV
Sbjct: 1143 ARLEGELSLADKDVTAKDSRF-KMPKFKMPSFGASA------PGKSIEASVDVSAPKVE- 1194
Query: 699 MAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIR--LP 756
DV LP +Q ++K D+ + DV L E +P+ + + LP
Sbjct: 1195 ---ADVSLPSMQ----GDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLP 1247
Query: 757 EMQVP--KVPDVHLPKAPEVKLPRAPEVQLKATKAE-----------------QAEGMEF 797
++Q+P K+P V L K P+V++ R P++ LK KAE QA G +
Sbjct: 1248 KVQMPSLKMPKVDL-KGPQVEV-RGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKL 1305
Query: 798 G---------------------FKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPC 836
FKMPK MP G + + GK EA ++S V
Sbjct: 1306 DGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVS---APGKSIEASVDLSAPKVEADM 1362
Query: 837 LQPEVDGEAHVGVPSLTLPSVELDL--------------PGALGLQG-----QVPAAKMG 877
P + G+ S+ PS +L+L P GL+G Q+P+ K+
Sbjct: 1363 SLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVP 1422
Query: 878 KGERVEGPEVAAGVREVGFRVPSVEIVTP----QLPAVEI---------EEGRLE----- 919
K + ++GPE+ ++ + P VE+ P LP+VE+ + GRLE
Sbjct: 1423 KVD-LKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSL 1481
Query: 920 ------MIETKVKPSSKFSLPKFGLSGP----------KVAKAEAEGA--GRATKLKVSK 961
++K K KF +P FG+S P K EA+ + LK +
Sbjct: 1482 ADKDLTTKDSKFK-MPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATD 1540
Query: 962 FAISLPKARVGAEA-----------EAKGAGEAGLLPALDLSIPQLSL-DAHLPSGKVEV 1009
+I P A + +A ++GAG G LP + + P + L +++V
Sbjct: 1541 LSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQM--PSFKMPKVDLKGPQIDV 1598
Query: 1010 AGADLKFKGPRFALPKFGVRGR------DTEAAELVPGVAELEG-------KGWGWDGRV 1056
G L KGP+ + V+ D +A A+LEG D +
Sbjct: 1599 KGPKLDLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKF 1658
Query: 1057 KMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAE----STAVQLKIPEVELVTLGAQEEGR 1111
KMPK KMPSFG+ A GK E D + P +A+ S LK ++ + + A E +
Sbjct: 1659 KMPKFKMPSFGVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQ 1718
Query: 1112 AEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQ 1171
A G V V + G AG +GH ++MP L +P+V L G + G +
Sbjct: 1719 A-GQVNVKLPE--GPLPEGAG---FKGHLPKVQMPSL--KMPKVALKG-PQMDVKGPKLD 1769
Query: 1172 STVPSAEGTAGYRVQVPQVTLSLPGAQV--------------------AGGELLVGEGVF 1211
P AE V P V +SLP +V A ++ + F
Sbjct: 1770 LKGPKAE------VMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKF 1823
Query: 1212 KMPTVTVPQLELDV-GLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGAER 1270
KMP +P + G S EA + + + + LP++ +
Sbjct: 1824 KMPKFKMPSFGVSAPGKSIEASV-DVSAPKVEAEVSLPSMQGDLKT-------------T 1869
Query: 1271 TFCLSLPDVELSPSGG----NHAEYQVAEGEGEAGHKLKVRLPRFGLVRAK-EGAEEGEK 1325
C+ LP +L G E QV EG G GH KV +P F + + +G + K
Sbjct: 1870 DLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVK 1929
Query: 1326 AKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGA----------------SG 1369
L+ P+ + ++ E S E + + ++ +GA
Sbjct: 1930 GAKLDLKGPKAEVTAPDV---EVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDS 1986
Query: 1370 RRGRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFR--FPRVSLSPKARSGSGD 1427
+ + ++P G++AP ++ APK P + LS + S
Sbjct: 1987 KFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSADLK 2046
Query: 1428 QEEGGLRVRLP 1438
+ G + V+LP
Sbjct: 2047 VQTGQVDVKLP 2057
Score = 199 bits (507), Expect = 1e-50
Identities = 400/1661 (24%), Positives = 647/1661 (38%), Gaps = 427/1661 (25%)
Query: 116 EIKGPRAKVAKLNIQ-SLSPVKKKKMVPGALGVPA-----------DLAPVDVEFSFPKF 163
++K P+ +V +++ SL V+ PGA A D+ D +F PKF
Sbjct: 2264 DLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKF 2323
Query: 164 SRLRRGL----KAEAVKGPVPAAPARRRLQLPR----LRVREVAEEAQAARLAAAAPPPR 215
L G+ K+ V A + LP L+ +++ + +A L A
Sbjct: 2324 KMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVD 2383
Query: 216 KAKVEAEVAAGA------------RFTAPQVELVGPRL------------------PGAE 245
E V GA F P+V+L GP++ P E
Sbjct: 2384 VKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVE 2443
Query: 246 VGVPQVSAPKAAPSAEAAGGFA----------------------LHLPTLGLGAPAPPAV 283
V P V AP A+ G + +P+ G+ AP ++
Sbjct: 2444 VSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGK-SI 2502
Query: 284 EAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAE 343
EA +V + P+VE SL ++ + + +S+ P+ D+ VD+ LP
Sbjct: 2503 EA-SVDVSAPKVEADG--SLSSMQG----DLKATDLSIQPPSADLEVQAGQVDVKLPEGP 2555
Query: 344 VEA----RGEAPEVALKMPRLSFPRFGARAKE--VAEAKVAKVSPEARVKGPRLRMPTFG 397
V +G P+V +MP P + + V K+ P+A V P + M
Sbjct: 2556 VPEGAGLKGHLPKV--QMPSFKMPEMDLKGPQLDVKGPKLDLKGPKAEVTAPDVEM---S 2610
Query: 398 LSLLEPRPAAPEVV--------------------ESKLKLPTIKMPSLGIGVSGPEVK-- 435
LS +E AP +SK K+P KMPS + G ++
Sbjct: 2611 LSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEAL 2670
Query: 436 -----VPKGPEVKLP------KAPEVKLPKVPEAALP------EVRLPEVELPKVSEMKL 478
+ ++ LP K ++ + + P A L +V+LPE +P+ + +K
Sbjct: 2671 VDVSELKVEADMSLPSMQGDLKTTDISI-QPPSAQLEVQAGQVDVKLPEGHVPEGAGLK- 2728
Query: 479 PKVPEMAVPEVRLPEVEL--PKVS------EMKLPKVPEMAVPEVRL-----------PE 519
+P++ +P ++PEV+L P++ ++K PK E+ P+V++ P
Sbjct: 2729 GHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKA-EVTAPDVKMSLSSMEVDVQAPR 2787
Query: 520 VQL-----------------LKVSEMKLPK--VPEMAVPEVRLPEVQLPKVSEMKL---- 556
+L K S+ K+PK +P V VSE+K+
Sbjct: 2788 AKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADG 2847
Query: 557 -----------------PEVSEVAVP----EVRLPEVQLPK-------VPEMKVPEMKLP 588
P +++ V +V+LPE +P+ +P++++P K+P
Sbjct: 2848 SFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMP 2907
Query: 589 KVPEMKLPEM--KLPEVQL--PKVPEMAVPDVHLPEVQLPKVP-EMKLPEMKLPEVKLPK 643
KV ++K P++ K P++ L PK E+ PDV EV LP V +++ P KL +L
Sbjct: 2908 KV-DLKGPQIDVKGPKLDLKGPKA-EVTAPDV---EVSLPSVEVDVEAPRAKLDGARLEG 2962
Query: 644 VPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVP---EVRLPEVQLPKV-SEMKLP----- 694
+A DV + + K+P+ K+P A EV + +V PKV +E+ LP
Sbjct: 2963 DLSLADKDVTAKDSKF-KMPKFKMPSFGVSAPGKSIEVSV-DVSAPKVEAEVSLPSMQGD 3020
Query: 695 -KVPEMAVP-------------DVHLPEVQLPKVCEMK--VPDMKLPEIKLPKVPEMAVP 738
K ++++ D+ LPE +P+ +K +P +++P K+PKV
Sbjct: 3021 LKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQ 3080
Query: 739 -DVHLPEVQL--PKVSEIRLPEMQVPKVPDVHLP-KAPEVKLPRAPEVQLKATKAEQAEG 794
DV P++ L PK +++ P+++V + P + + +AP KL A + +
Sbjct: 3081 IDVKGPKLDLKGPK-TDVTAPDVEVSQ-PGMEVDVEAPGAKLDGARLEGDLSLADKDVTA 3138
Query: 795 MEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTL 854
+ FKMPK MP G + + GK E +VS V P + G+ S+
Sbjct: 3139 KDSKFKMPKFKMPSFGVS---APGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEP 3195
Query: 855 PSVELD---------------LPGALGLQG-----QVPAAKMGKGERVEGPEVAAGVREV 894
PS +L+ L GA GL+G Q+P+ KM K +R +GP++ ++
Sbjct: 3196 PSAQLEVQAGQVDVKLPEGHVLEGA-GLKGHLPKLQMPSFKMPKVDR-KGPQIDIKGPKL 3253
Query: 895 GFRVPSVEIVTPQL----PAVEIE-------------EGRLEMIETKVKPS-SKFSLPKF 936
+ P +++ P + P++E++ EG L + + V SKF +PKF
Sbjct: 3254 DLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKF 3313
Query: 937 GLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGA-----EAEAKGAGEAGLLPALDL 991
K+ A G++ + V +S PKA + + K + LP++DL
Sbjct: 3314 -----KMPSYRASAPGKSIQASVD---VSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDL 3365
Query: 992 SIPQLSLDAHLPSG-----------------------KVEVAGADLKFKGPRFAL--PKF 1026
+ +D LP G KV++ + KGP+ L PK
Sbjct: 3366 EVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKA 3425
Query: 1027 GVRGRDTEAAELVPGV-------------AELEGK-------GWGWDGRVKMPKLKMPSF 1066
V D E + +P V A LEG D + KMPK KMPSF
Sbjct: 3426 EVTVPDVEVS--LPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSF 3483
Query: 1067 GL-ARGKEAEVQGDRASPGEKAE----STAVQLKIPEVELVTLGAQEEGRAEGAVAVSGM 1121
G+ A G+ E D ++P +A+ S LK ++ + A E +A V V
Sbjct: 3484 GVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQA---VQVDVE 3540
Query: 1122 QLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEGTA 1181
L G AG +GH + MP L P+V+L G + G + P AE
Sbjct: 3541 LLEGPVPEGAG---LKGHLPKVEMPSL--KTPKVDLKG-PQIDVKGPKLDLKGPKAE--- 3591
Query: 1182 GYRVQVPQVTLSLPGAQV--------------------AGGELLVGEGVFKMPTVTVPQL 1221
V+VP V +SLP +V A ++ + FKMP +P
Sbjct: 3592 ---VRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSF 3648
Query: 1222 ELDV-GLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVE 1280
+ G S EA +A + + LP++ + QPP A+ DV+
Sbjct: 3649 RVSAPGKSMEASVDVSAP-KVEADVSLPSMQGDLKT--TDLSIQPPSADLKVQAGQMDVK 3705
Query: 1281 LSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFSQ 1340
L P G QV EG G H KV +P + + + + K PKL L S+
Sbjct: 3706 L-PEG------QVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVD-IKGPKLDLK---VSK 3754
Query: 1341 SEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAA-P 1399
+E+ + S E V V+ PR L S EGD +
Sbjct: 3755 AEVTAPDVEVSLPSVE-----------------VDVQAPRAKLD-----SAQLEGDLSLA 3792
Query: 1400 KSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
V K KF+ P+ + S G E + V P V
Sbjct: 3793 DKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKV 3833
Score = 199 bits (507), Expect = 1e-50
Identities = 381/1547 (24%), Positives = 632/1547 (40%), Gaps = 342/1547 (22%)
Query: 141 VPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEA--VKGP-VPAAPARRRLQLPRLRVR- 196
VP G+ L V + P F + LK VKGP + + + P + V
Sbjct: 2886 VPEGAGLKGHLPKVQM----PSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSL 2941
Query: 197 ---EVAEEAQAARLAAAAPPPRKAKVEAEVAA-GARFTAPQVEL--VGPRLPG------A 244
EV EA A+L A + + +V A ++F P+ ++ G PG
Sbjct: 2942 PSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVSV 3001
Query: 245 EVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPA---VEAPAVGIQVPQVELPA-- 299
+V P+V A + PS + L T + P A V+A V +++P+ +P
Sbjct: 3002 DVSAPKVEAEVSLPSMQG------DLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGA 3055
Query: 300 -----LPSLPTLPT--LPCLETREGAVSVVVPTLDVAAPTVGV-----DLALPGAEVEAR 347
LP L +P+ +P ++ + + V P LD+ P V +++ PG EV+
Sbjct: 3056 GLKGHLPKLQ-MPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDV- 3113
Query: 348 GEAPEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSL------L 401
EAP L RL +++ A + +++ K P+ +MP+FG+S +
Sbjct: 3114 -EAPGAKLDGARLE--------GDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEV 3164
Query: 402 EPRPAAPEVVESKLKLPT----IKMPSLGIGVSGPEVKVPKGP-EVKLPKAPEVKLPKVP 456
+AP+V E+ L LP+ +K + I +++V G +VKLP+ ++ +
Sbjct: 3165 LVDVSAPKV-EADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGL- 3222
Query: 457 EAALPEVRLPEVELPKVS------EMKLPKV----PEMAVPEVRLPEVELPKVSEMKLPK 506
+ LP++++P ++PKV ++K PK+ P+M +V P+VE+ + S +
Sbjct: 3223 KGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDLKGPKM---DVTAPDVEVSQPSMEVDVE 3279
Query: 507 VPEMAVPEVRLPEVQLL-------KVSEMKLPK--VPE----------MAVPEVRLP--- 544
P + RL L K S+ K+PK +P A +V P
Sbjct: 3280 APGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPKAE 3339
Query: 545 -EVQLPKVS--------EMKLPEVS---EVAVPEVRLPEVQLPK-------VPEMKVPEM 585
+V LP + ++LP V + +V+LPE +P+ +P++++P
Sbjct: 3340 ADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSF 3399
Query: 586 KLPKVPEMKLPEMKL--PEVQLPKVP--EMAVPDVHLPEVQLPKVP-EMKLPEMKLPEVK 640
K+PKV ++K P++ + P++ L KVP E+ VPDV EV LP V +++ P KL +
Sbjct: 3400 KMPKV-DLKSPQVDIKGPKLDL-KVPKAEVTVPDV---EVSLPSVEVDVQAPRAKLDGAR 3454
Query: 641 LPKVPEMAVPDVHLPEVQLPKVPEMKLPKM----PEMAVP---EVRLPEVQLP------- 686
L +A DV + + K+P+ K+P P ++ +V P+V+
Sbjct: 3455 LEGDLSLAEKDVTAKDSKF-KMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQ 3513
Query: 687 ---KVSEMKL-PKVPEMAVP----DVHLPEVQLPKVCEMK--VPDMKLPEIKLPKVPEMA 736
K +++ + P ++ V DV L E +P+ +K +P +++P +K PKV ++
Sbjct: 3514 GDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKV-DLK 3572
Query: 737 VP--DVHLPEVQL--PKVSEIRLPEMQVPKVPDVHLP-KAPEVKLPRAPEVQLKATKAEQ 791
P DV P++ L PK +E+R+P+++V +P V + +AP+ KL + +
Sbjct: 3573 GPQIDVKGPKLDLKGPK-AEVRVPDVEV-SLPSVEVDVQAPKAKLDAGRLEGDLSLADKD 3630
Query: 792 AEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPS 851
+ FKMPK MP R +P GK EA +VS V P + G+ S
Sbjct: 3631 VTAKDSKFKMPKFKMPSF-RVSAP--GKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLS 3687
Query: 852 LTLPSVEL--------------DLPGALGLQG-----QVPAAKMGKGERVEGPEVAAGVR 892
+ PS +L +P GL+ ++P+ KM K + ++GP+V
Sbjct: 3688 IQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVD-LKGPQVDIKGP 3746
Query: 893 EVGFRVPSVEIVTPQ----LPAVEIE-------------EGRLEMIETKVKPS-SKFSLP 934
++ +V E+ P LP+VE++ EG L + + V SKF +P
Sbjct: 3747 KLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMP 3806
Query: 935 KFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIP 994
KF K+ G++ + V +S PK EA+ G L DLSI
Sbjct: 3807 KF-----KMPSFGVSAPGKSIEASVH---VSAPKV----EADVSLPSMQGDLKTTDLSIQ 3854
Query: 995 QLSLD------------------------AHLPS--------GKVEVAGADLKFKGPRFA 1022
S D HLP KV++ G ++ KGP+
Sbjct: 3855 PHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLD 3914
Query: 1023 L--PKFGVRGRDTEAAELVPGV-AELEGKGWGWDG-------------------RVKMPK 1060
L PK V D E + +P V ++E G DG + KMPK
Sbjct: 3915 LKDPKVEVTAPDVEVS--LPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPK 3972
Query: 1061 LKMPSFGL-ARGKEAEVQGDRASPGEKAE-----------STAVQLKIPEVELVTLGAQE 1108
KMPSFG+ A GK E D +P +A+ +T + ++ P +L Q
Sbjct: 3973 FKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADLEVQAGQV 4032
Query: 1109 EGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQ 1168
+ + G L G + + +MP + + PQ+++ G + G
Sbjct: 4033 DVKLPEGPVPEGASLKGH--------LPKVQMPSFKMPKVDLKGPQIDVKG-PKLDLKGP 4083
Query: 1169 QAQSTVPSAE-GTAGYRVQVPQVTLSLPGAQVAGGELLVGEGV------FKMPTVTVPQL 1221
+A+ T P + + V V L G Q+ G L + V FKMP +P
Sbjct: 4084 KAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSF 4143
Query: 1222 ELDVGLSREAQAGEAATGEGGLRLK----LPTLGARARVGGEGAEEQPPGAERTFCLSLP 1277
G+S ++ EA+ L+ K LP++ + Q P A+
Sbjct: 4144 ----GVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKT--TDLSIQSPSADLEVQAGQV 4197
Query: 1278 DVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVG 1337
DV+L P G + +G G GH KV++P + + + + K PKL L
Sbjct: 4198 DVKL-PEG------PLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVD-VKGPKLDLKGPK 4249
Query: 1338 FSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDA 1397
V PS E + E GA R+ L +K S+
Sbjct: 4250 ADVMTPVVEVSLPSMEVDVE------APGAKLDSVRLEGDLSLADKDMTAKDSKF----- 4298
Query: 1398 APKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVR----LPSV 1440
K PKF+ P +S +S + L+V LPS+
Sbjct: 4299 --------KMPKFKMPSFGVSAPGKSIEASLDVSALKVEADVSLPSM 4337
Score = 179 bits (454), Expect = 2e-44
Identities = 360/1519 (23%), Positives = 594/1519 (39%), Gaps = 320/1519 (21%)
Query: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175
++KGP+ + + +K K A V L V+V+ P+ L+ +
Sbjct: 3735 DLKGPQVDIKGPKLD----LKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLS 3790
Query: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGA-RFTAPQV 234
+ ++P+ ++ A + A+ KVEA+V+ + +
Sbjct: 3791 LADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAP-KVEADVSLPSMQGDLKTT 3849
Query: 235 EL-VGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVP 293
+L + P V QV G HLP + + P+ + P V ++ P
Sbjct: 3850 DLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQM-----PSFKMPKVDLKGP 3904
Query: 294 QVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEV 353
++++ P L+ ++ V V P ++V+ P+V VD+ PGA+++
Sbjct: 3905 EIDIKG----------PKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLD-------- 3946
Query: 354 ALKMPRLSFPRFGARAK-EVAEAKVAKVSPEARVKGPRLRMPTFGLSLL-EPRPAAPEV- 410
GAR + +++ A + +++ K P+ +MP+FG+S + A+ +V
Sbjct: 3947 ------------GARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVT 3994
Query: 411 ---VESKLKLPT----IKMPSLGIGVSGPEVKVPKGP-EVKLPKAPEVKLPKVPEAA--- 459
VE+ + LP+ +K L + +++V G +VKLP+ P VPE A
Sbjct: 3995 APKVEADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGP------VPEGASLK 4048
Query: 460 --LPEVRLPEVELPKVSEMKLPKVPEMAVPEVRL----PEVELPKVSEMKLPKVPEMAVP 513
LP+V++P ++PKV ++K P++ ++ P++ L EV P V ++ P
Sbjct: 4049 GHLPKVQMPSFKMPKV-DLKGPQI-DVKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAP 4106
Query: 514 EVRLPEVQL------------LKVSEMKLP--KVPEMAVP------EVRLPEVQLPKVSE 553
+L VQL K S+ K+P K+P V E + +L ++
Sbjct: 4107 RAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKAD 4166
Query: 554 MKLPEVS--------EVAVPEVRLPEVQLPKVPEMKVPEMKLPK-------VPEMKLPEM 598
+ LP + + P L EVQ +V ++K+PE LPK +P++++P +
Sbjct: 4167 VSLPSMQGDLKTTDLSIQSPSADL-EVQAGQV-DVKLPEGPLPKGAGLKGHLPKVQMPCL 4224
Query: 599 KLPEVQLPKVPEMAV-----------PDVHLP--EVQLPKVP-EMKLPEMKLPEVKLPKV 644
K+P+V L K P++ V DV P EV LP + +++ P KL V+L
Sbjct: 4225 KMPKVAL-KGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGD 4283
Query: 645 PEMAVPDVHLPEVQLPKVPEMKLPKMPEMA----------------VPEVRLPEVQLP-K 687
+A D+ + + K+P+ K+P A +V LP +Q K
Sbjct: 4284 LSLADKDMTAKDSKF-KMPKFKMPSFGVSAPGKSIEASLDVSALKVEADVSLPSMQGDLK 4342
Query: 688 VSEMKL-PKVPEMAV----PDVHLPEVQLPKVCEMK--VPDMKLPEIKLPKVPEMAVP-- 738
+ + + P ++ V DV LPE + + +K +P +++P K+PKV ++ P
Sbjct: 4343 TTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKV-DLKGPQI 4401
Query: 739 DVHLPEVQL--PKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAE------ 790
DV++P++ L PKV E+ P + DV LP + EV + +AP +L +T+ E
Sbjct: 4402 DVNVPKLDLKGPKV-EVTSPNL------DVSLP-SMEVDI-QAPGAKLDSTRLEGDLSLA 4452
Query: 791 --QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKL----VTLPCLQ------ 838
+ FKMPK MP G S GK E +VS +++P +Q
Sbjct: 4453 DKDVTAKDSKFKMPKFKMPSFGML---SPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTT 4509
Query: 839 ------PEVDGEAHVGVPSLTLPSVELDLPGALGLQG-----QVPAAKMGKGERVEGPEV 887
P D E G L LP E +P GL+G ++P+ KM K + ++GP+V
Sbjct: 4510 DLRIQAPSADLEVQAGQVDLKLP--EGHMPEVAGLKGHLPKVEMPSFKMPKVD-LKGPQV 4566
Query: 888 AAGVREVGFRVPSVEIVTP----QLPAVEIE-------------EGRLEMIETKVK-PSS 929
++ + P E++ P LP+VE + EG L + V S
Sbjct: 4567 DVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDS 4626
Query: 930 KFSLPKFGLSG-----PKVAKAEAEGAGRAT-KLKVSKFAISLPKARVGAEAEAKGAGEA 983
KF PK SG KV+ + +E G T K S F I G
Sbjct: 4627 KFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEG----------- 4675
Query: 984 GLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGV- 1042
DL P + L G+V G D KFK F +PK T LVPG
Sbjct: 4676 ------DLHDPSRDGNLGLAVGEV---GMDSKFKKLHFKVPKVSFSSTKTPKDSLVPGAK 4726
Query: 1043 ------------AELEGKGWGWDGRVKMPKLKMPSFGLARGKEAEV-------QGDRASP 1083
+E P ++MP G A + + + SP
Sbjct: 4727 SSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSP 4786
Query: 1084 GEKAESTAVQLKIPEVEL-------VTLGAQEEGRAEGAVAVSGMQ-LSGLKVSTAGQVV 1135
E T Q+ +P L + G+Q + + +Q G+ S A
Sbjct: 4787 CEDVTLTKYQVTVPRAALAPELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQA---- 4842
Query: 1136 TEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAE--GTAGYRVQVP----- 1188
E H L + +SL QV F + Q VP + G V P
Sbjct: 4843 -ESHSGPLN-SMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGE 4900
Query: 1189 QVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLP 1248
+V LP Q+ V +G P V L+ V EA + +A G LK+P
Sbjct: 4901 RVQCPLPSTQLPSPGTCVSQG----PEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMP 4956
Query: 1249 TL------GARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGH 1302
+ + + G + + + L L E++P H + E +GE G
Sbjct: 4957 KIKLPSFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLP-PERDGEKGR 5015
Query: 1303 KLK--VRLPRFGLVR---AKEGAEEGEKAKSPKLRLPRVG--FSQSEMVTGEGSPSPEEE 1355
K +P+ L + +K G ++ P L G F +E + +G
Sbjct: 5016 STKPGFAMPKLALPKMKASKSGVSLPQRDVDPSLSSATAGGSFQDTEKASSDGG------ 5069
Query: 1356 EEEEEEGSGEGASGRRG----RVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFR 1411
G+ A+G G R +V +P +G A P S + K V +
Sbjct: 5070 --RGGLGATASATGSEGVNLHRPQVHIPSLGFAKPDLRS------SKAKVEVSQPEADLP 5121
Query: 1412 FPRVSLSPKARS---GSGD 1427
P+ LS + S G GD
Sbjct: 5122 LPKHDLSTEGDSRGCGLGD 5140
Score = 178 bits (451), Expect = 4e-44
Identities = 362/1486 (24%), Positives = 594/1486 (39%), Gaps = 319/1486 (21%)
Query: 173 EAVKGPVPAAPARRRLQLPRLRVREVA--EEAQAARLAAAAPPPRKAKVEAEVAAGARFT 230
+ +G P R+++ L+ + A E + R + P R + +A AG
Sbjct: 469 DTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLK 528
Query: 231 APQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGI 290
+VE G +PG E P A + G L + E I
Sbjct: 529 GEEVEGAG-WMPGRE---PTTHAEAQGDEGDGEEG----LQRTRITEEQDKGREDTEGQI 580
Query: 291 QVPQVELPALPSLPTLPTLPCLE-----TREGAVSVVVPTLDVAAPTVGVDLALPGAEVE 345
++P+ ++P+L P+ T E T +G T D + G + +
Sbjct: 581 RMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEATATADRREQRRTEE----GLKDK 636
Query: 346 ARGEAPEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLL-EPR 404
++ K+ + + + + + E +VA + +++ K P+ +MP FG S +
Sbjct: 637 EDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVA--TKDSKFKMPKFKMPLFGASAPGKSM 694
Query: 405 PAAPEVVESKLKLPT--------IKMPSLGIGVSGPEVKVPKGP-EVKLPKAPEVKLPKV 455
A+ +V K++ +K L + +++V G +VKLP+ P +
Sbjct: 695 EASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDGQVDVKLPEGP------L 748
Query: 456 PEAA-----LPEVRLPEVELPKVSEMKLPKV------PEMAVPEVRLP------EVELP- 497
PE A LP+V+ P +++PKV ++K PK+ E+ P+V++ +V+ P
Sbjct: 749 PEGASLKGHLPKVQRPSLKMPKV-DLKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPR 807
Query: 498 ---------------------KVSEMKLP--KVPEMAVP----------EVRLPEVQL-L 523
K S+ K+P K+P V +V P+V+ +
Sbjct: 808 AKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADV 867
Query: 524 KVSEMKLP-KVPEMAV-PEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMK 581
+S M+ K ++++ P EVQ +V ++KLP E VPE P+V LPKV +
Sbjct: 868 SLSSMQGDLKATDLSIQPPSADLEVQAGQV-DVKLP---EGPVPEGAGPKVHLPKV---E 920
Query: 582 VPEMKLPKVPEMKLP--EMKLPEVQL--PKVPEMAVPDVHLPEVQLPKVP-EMKLPEMKL 636
+P K+PKV ++K P ++K P++ L PK E+ PD EV LP + +++ + KL
Sbjct: 921 MPSFKMPKV-DLKGPQIDVKGPKLDLKGPKA-EVTAPD---GEVSLPSMEVDVQAQKAKL 975
Query: 637 PEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPE--VRLPEVQLPKV-SEMKL 693
L +A DV + + K+P+ K+P A + L +V PKV +++ L
Sbjct: 976 DGAWLEGDLSLADKDVTAKDSKF-KMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSL 1034
Query: 694 PKVP-EMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMA--VPDVHLPEVQLPKV 750
P + ++ D+ + + D+KLPE LP+ + +P V +P ++PKV
Sbjct: 1035 PSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKV 1094
Query: 751 SEIRLPEMQV--PKVPDVHLPKAP------EVKLP------RAPEVQLKATKAE------ 790
+ ++ P++ V PK+ D+ PKA EV LP AP +L + + E
Sbjct: 1095 A-LKGPQVDVKGPKL-DLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLA 1152
Query: 791 --QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKL----VTLPCLQ------ 838
+ FKMPK MP G A +P GK EA +VS V+LP +Q
Sbjct: 1153 DKDVTAKDSRFKMPKFKMPSFG-ASAP--GKSIEASVDVSAPKVEADVSLPSMQGDLKTT 1209
Query: 839 ------PEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMG---------KGERVE 883
P D E H G + L +E +P G +G +P +M KG +VE
Sbjct: 1210 DLSIQPPSADLEVHAGQVDVKL--LEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVE 1267
Query: 884 ---------GPEVAAGVREVGFRVPSVEIVTPQLPAVEIE----EGRLEMIETKV-KPSS 929
G + EV +PSVE V Q P +++ +G L + + V S
Sbjct: 1268 VRGPKLDLKGHKAEVTAHEVAVSLPSVE-VDMQAPGAKLDGAQLDGDLSLADKDVTAKDS 1326
Query: 930 KFSLPKF------------------GLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARV 971
KF +PKF LS PKV +A+ LK + +I P +
Sbjct: 1327 KFKMPKFKMPSFGVSAPGKSIEASVDLSAPKV-EADMSLPSMQGDLKTTDLSIQPPSTDL 1385
Query: 972 GAEA-----------EAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPR 1020
+A +GAG G LP L + P + KV++ G ++ KGP+
Sbjct: 1386 ELQAGQLDVKLPEGPVPEGAGLKGHLPKLQM--PSFKVP------KVDLKGPEIDIKGPK 1437
Query: 1021 FAL--PKFGVRGRDTEAAELVPGV-AELEGKGWGWDG-------------------RVKM 1058
L PK V D E + +P V ++E G DG + KM
Sbjct: 1438 LDLKDPKVEVTAPDVEVS--LPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKM 1495
Query: 1059 PKLKMPSFGL-ARGKEAEVQGDRASPGEKAE-----------STAVQLKIPEVELVTLGA 1106
PK KMPSFG+ A GK E D ++P +A+ +T + ++ P +L
Sbjct: 1496 PKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAG 1555
Query: 1107 QEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTP 1166
Q + + G L G + + +MP + + PQ+++ G +
Sbjct: 1556 QVDVKLPEGPVSEGAGLKG--------HLPKVQMPSFKMPKVDLKGPQIDVKG-PKLDLK 1606
Query: 1167 GQQAQSTVPSAE-GTAGYRVQVPQVTLSLPGAQVAGGELLVGEGV------FKMPTVTVP 1219
G + + T P + + V V L GAQ+ G L + V FKMP +P
Sbjct: 1607 GPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMP 1666
Query: 1220 QLELDVGLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDV 1279
G+S ++ EA+ + +V + + G +T LS+
Sbjct: 1667 SF----GVSAPGKSIEASVDV-----------SEPKVEADVSLPSMQGDLKTTDLSIQ-- 1709
Query: 1280 ELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFS 1339
SPS A+ E +AG ++ V+LP L K + P L++P+V
Sbjct: 1710 --SPS---------ADLEVQAG-QVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALK 1757
Query: 1340 QSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLP--RVGLAAPSKA--SRGQEG 1395
+M + + + + G A V V LP V + AP S EG
Sbjct: 1758 GPQM----------DVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEG 1807
Query: 1396 D-AAPKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
D + V K KF+ P+ + S G E + V P V
Sbjct: 1808 DLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKV 1853
Score = 105 bits (261), Expect = 4e-22
Identities = 48/87 (55%), Positives = 67/87 (77%)
Query: 15 ELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFEN 74
E E+ ++TE + G SG +V GGG +GIFV+++ +DS AA+ +L+EGDQLLS VFFEN
Sbjct: 109 EATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTVFFEN 168
Query: 75 FKYEDALRLLQCAEPYKVSFCLKRTVP 101
KYEDAL++LQ +EPYKV F ++R +P
Sbjct: 169 IKYEDALKILQYSEPYKVQFKIRRQLP 195
Score = 103 bits (257), Expect = 1e-21
Identities = 336/1476 (22%), Positives = 546/1476 (36%), Gaps = 292/1476 (19%)
Query: 116 EIKGPRAKVAKLNIQ-SLSPVKKKKMVPGA------LGVPADLAPVDV-----EFSFPKF 163
++KGP+ +V N+ SL ++ PGA L LA DV +F PKF
Sbjct: 4409 DLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKF 4468
Query: 164 SRLRRGL----KAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKV 219
G+ K+ V V A + +P ++ + + L AP
Sbjct: 4469 KMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQ-----GDLKTTDLRIQAP-----SA 4518
Query: 220 EAEVAAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPA 279
+ EV AG QV+L +LP E +P+V+ K HLP + +
Sbjct: 4519 DLEVQAG------QVDL---KLP--EGHMPEVAGLKG------------HLPKVEM---- 4551
Query: 280 PPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLAL 339
P+ + P V ++ PQV++ P L+ + V+ P ++V+ P+V D+
Sbjct: 4552 -PSFKMPKVDLKGPQVDVKG----------PKLDLKGPKAEVMAPDVEVSLPSVETDVQA 4600
Query: 340 PGAEVE-ARGEAP------EVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLR 392
PG+ ++ AR E +VA K + P+ E + KV+ S E
Sbjct: 4601 PGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIE------- 4653
Query: 393 MPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSL--GIGVSGPEVKVPKGPEVKLPKAPEV 450
G + + +VES + + PS +G++ EV G + K K
Sbjct: 4654 ----GNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEV----GMDSKFKKLHF- 4704
Query: 451 KLPKVPEAALPEVRLPEVELPK--VSEMKLPKVP--EMAVPEVRLPEVELPKVSEMKLPK 506
KVP+ + + P+ L S + L +P L +V M++PK
Sbjct: 4705 ---KVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPK 4761
Query: 507 VPEMAVPEVRLP------EVQLLKVSEMKLPKVPEMAVPEVRL-PEV--QLPKVSEMKLP 557
V P RL E +L E ++ VP L PE+ ++P S+ +P
Sbjct: 4762 VGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALAPELALEIPSGSQADIP 4821
Query: 558 EVSEVAVPEVRLPEVQLPKVPEMKVPEMKLP--KVPEMKLPEMKLPEVQLPK----VPEM 611
+++ PE VP + P + + L ++ P+ PK VP+M
Sbjct: 4822 LPKTECSTDLQPPE----GVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQM 4877
Query: 612 AVP--DVHLP---EVQLPKVPEMKLPEMKLPEVKLPKV-------PEMAVPDVHLPEVQL 659
AVP D+H V P P ++ + LP +LP PE V + V
Sbjct: 4878 AVPEGDLHAAVGAPVMSPLSPGERV-QCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAP 4936
Query: 660 PKVPEMKLP---KMPEMAVPEVRLPEVQLPKVSEMKLPKV-PEMAVPDVHLP------EV 709
+ P K + +P+++LP + E PKV PE +V D L EV
Sbjct: 4937 GEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETG-PKVDPECSVEDSKLSLVLDKDEV 4995
Query: 710 QLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLP 769
M +P + E P A+P + LP+++ K S + LP+ V P +
Sbjct: 4996 APQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASK-SGVSLPQRDVD--PSLSSA 5052
Query: 770 KA------PEVKLPRAPEVQLKAT-KAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGE 822
A E L AT A +EG+ P++ +P LG A+ R +
Sbjct: 5053 TAGGSFQDTEKASSDGGRGGLGATASATGSEGVNL--HRPQVHIPSLGFAKPDLRSS--K 5108
Query: 823 AGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPG---ALGLQGQVPAAKMGKG 879
A EVS QPE D L LP +L G GL G VP ++
Sbjct: 5109 AKVEVS---------QPEAD---------LPLPKHDLSTEGDSRGCGL-GDVPVSQPCGE 5149
Query: 880 ERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLS 939
PE + R P E++T + P E TK S F +PKF +
Sbjct: 5150 GIAPTPEDPL---QPSCRKPDAEVLTVESPEEEAM--------TKYSQESWFKMPKFRMP 5198
Query: 940 GPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKG----AGEAGLLPALDLSIPQ 995
+ + + GAG KL+V++ + A G EA AK + + A+ L +P+
Sbjct: 5199 SLRRSFRDRGGAG---KLEVAQ---TQAPAATGGEAAAKVKEFLVSGSNVEAAMSLQLPE 5252
Query: 996 LSLDAHLPSGK--VEVAGADLKFKGPRFALPKFGVRGRDTEAAE--LVPGVAELEGKGWG 1051
+ K ++ DL G + L G+ G + +E + P L
Sbjct: 5253 ADAEVTASESKSSTDILRCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPLP----- 5307
Query: 1052 WDGRVKMPKLKMPSFGLARGKEAEVQ-----GDRASPGEKAESTAVQLKIPEVELVTLGA 1106
+MP +++P + G+ E D AS +K E + Q PE L +
Sbjct: 5308 ----FQMPGMRLPETQVLPGEIDETPLSKPGHDLASMEDKTEKWSSQ---PEGPLKLKAS 5360
Query: 1107 QEEGRAEGAV---------AVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVEL 1157
+ ++ +V +V ++ L V D + P+ +
Sbjct: 5361 STDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQCPEANI 5420
Query: 1158 TGFGEAGTPGQQAQSTVPSAEGTAGYR----------VQVPQVTLSLPGAQVAGGELLVG 1207
+PG S + + G G + + +V + + GAQV E+ +
Sbjct: 5421 DTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPISKVRVHIQGAQVESQEVTIH 5480
Query: 1208 EGVF-KMPTVTVPQ-LELDVGLSREAQAGEAATGEGG---LRLKLPTLGARARV------ 1256
V + ++VP+ + E E T G L++K+P +ARV
Sbjct: 5481 SIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSLLKVKIPEPHTQARVYTTMTQ 5540
Query: 1257 ---GGEGAEEQP----PGAERTFCLSLPDV----ELSPSGGNHAEYQVAEGEGEAGHKL- 1304
EG EE P PG + PD E+ S N Q E +GH+L
Sbjct: 5541 HSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEMISSSVNVLGQQTLTFEVPSGHQLA 5600
Query: 1305 --------------------KVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMV 1344
+ P RA + E +K+ LP +GFS S
Sbjct: 5601 DSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDKPESKKSGLLWFWLPNIGFSSSVDE 5660
Query: 1345 TGEGSPSPEE-----EEEEEEEGSGEGASGRRGRVRVRLPRVGL-AAPSKASRG-QEGDA 1397
TG S + + + + E E + R P++G ++P+K S+ ++G
Sbjct: 5661 TGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKAGWFRFPKLGFSSSPTKKSKSTEDGAE 5720
Query: 1398 APKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGL 1433
+ ++E++ F R S SP+ ++EEG L
Sbjct: 5721 LEEQKLQEETITFFDARESFSPE------EKEEGEL 5750
Score = 53.5 bits (127), Expect = 1e-06
Identities = 119/614 (19%), Positives = 228/614 (37%), Gaps = 129/614 (21%)
Query: 922 ETKVKPSSKFSLPKFGLSGPKVAKAEA-EGAGRATKL-------KVSKFAISLPKARVGA 973
+ +V P+ LP L P++ + EG RA +L + + A++ K R
Sbjct: 384 DREVMPAQSMPLPT-ELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETAVAQRKPRAQP 442
Query: 974 EAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKF------- 1026
GE L +L++ I +LSL G ++ +++ + PKF
Sbjct: 443 TPGMSREGEGEGLQSLEIGIARLSL-RDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKE 501
Query: 1027 ------------------------GVRGRDTEAAELVPG--------------------- 1041
G++G + E A +PG
Sbjct: 502 PERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEEGLQ 561
Query: 1042 ---VAELEGKGW-GWDGRVKMPKLKMPSFGLARGKEAEVQGDRAS----PGEKAESTAVQ 1093
+ E + KG +G+++MPK K+PS G + K + ++A+ G + E+TA
Sbjct: 562 RTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEATATA 621
Query: 1094 LKIPEVELVTLGAQEEGRAEGAVAVSGMQL-SGLKVSTAGQVVTEGHDA---------GL 1143
+ E G +++ ++ + +QL K Q++TE A
Sbjct: 622 DR-REQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMPKF 680
Query: 1144 RMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEG------------TAGYRVQVPQVT 1191
+MP G S P + + P +A ++ S +G +A VQ QV
Sbjct: 681 KMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDGQVD 740
Query: 1192 LSLPGAQVAGGELLVGE-GVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL 1250
+ LP + G L G + P++ +P+++L G + + +A +++ L ++
Sbjct: 741 VKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLK-GPKLDLKGPKAEVTAPDVKMSLSSM 799
Query: 1251 GARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPR 1310
V + + GA LSL D E++ +++++ K ++P
Sbjct: 800 ----EVDVQAPRAKLDGARLEGDLSLADKEVT---AKDSKFKMP----------KFKMPS 842
Query: 1311 FGLVRAKEGAEEGEKAKSPKLRLP-RVGFSQSEMVTGEGSPSPEEEEEEEEEGS------ 1363
FG+ + E+ +PK+ + Q ++ + S P + E + G
Sbjct: 843 FGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLP 902
Query: 1364 ----GEGASGRRGRVRV-----RLPRVGLAAPSKASRGQEGD-AAPKSPVREKSPKFRFP 1413
EGA + +V ++P+V L P +G + D PK+ V + P
Sbjct: 903 EGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLP 962
Query: 1414 RVSLSPKARSGSGD 1427
+ + +A+ D
Sbjct: 963 SMEVDVQAQKAKLD 976
Score = 44.3 bits (103), Expect = 9e-04
Identities = 80/360 (22%), Positives = 128/360 (35%), Gaps = 52/360 (14%)
Query: 1105 GAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEG--HDAGLRMPPL-GISLP-QVELTGF 1160
G++ E RAE V Q L + EG + GLR L G +L Q + T
Sbjct: 374 GSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETAV 433
Query: 1161 GEAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQ 1220
+ Q EG +++ LSL G ++ E ++ + P+
Sbjct: 434 AQRKPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPK 493
Query: 1221 LELDVGLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQP----PGAERTFCLSL 1276
E + + G K ++A G +G E + PG E T
Sbjct: 494 FAFSTEKEPERERRLSTPQRG----KRQDASSKAGTGLKGEEVEGAGWMPGREPT----- 544
Query: 1277 PDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKE-GAEEGE-KAKSPKLRLP 1334
HAE Q EG+GE G L R + ++ G E+ E + + PK ++P
Sbjct: 545 ----------THAEAQGDEGDGEEG------LQRTRITEEQDKGREDTEGQIRMPKFKIP 588
Query: 1335 RVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVR--------------LPR 1380
+G+S S+ T G E+ E+ EG + RR + R +
Sbjct: 589 SLGWSPSKH-TKTGREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTK 647
Query: 1381 VGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
+ L K + ++ + V K KF+ P+ + S G E + V P V
Sbjct: 648 IQLIHDEKRLKKEQ--ILTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKV 705
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 168 bits (426), Expect = 3e-41
Identities = 190/645 (29%), Positives = 292/645 (45%), Gaps = 120/645 (18%)
Query: 292 VPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAP 351
VP+ E PA +P +P +E + V VP + P V LP EV + P
Sbjct: 10460 VPRKEPPA--KVPEVPKKIVVEEK-----VRVPE-EPRVPPTKVPEVLPPKEVVPEKKVP 10511
Query: 352 EVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVV 411
K P P+ KEV K V P + + P ++P + + P PE +
Sbjct: 10512 VPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAV-PEKKVPEAI 10570
Query: 412 ESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPE--VRLPEVE 469
K + P ++P V PE KVP P K P+ VK+P+ P+ +PE V +P +
Sbjct: 10571 PPKPESPPPEVPEAPKEVV-PEKKVPAAPPKK-PEVTPVKVPEAPKEVVPEKKVPVPPPK 10628
Query: 470 LPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKV---------------------- 507
P+V K+P+VP++AVPE ++PE PK E P+V
Sbjct: 10629 KPEVPPTKVPEVPKVAVPEKKVPEAIPPK-PESPPPEVFEEPEEVALEEPPAEVVEEPEP 10687
Query: 508 ---------PEMAVPEVRLPEVQLLK--VSEMKLPKVPEMAVPEVRLPEV--QLPKVSEM 554
P+ VPE + P V K + +K+P+VP+ VPE ++P V + P+
Sbjct: 10688 AAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPA 10747
Query: 555 KLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMK----LPKVPEMKLPEM-KLPEVQLPKVP 609
K+PEV + VPE ++ + P+VP KVPE+ L + P + +PE + P ++ + P
Sbjct: 10748 KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEP 10807
Query: 610 EMAVPDVHL---------------PEVQLPKVPEMK---LPEMKLPEVKLPKVPEMAVP- 650
E P+ + PEV P VPE +PE K+P +K P+ P P
Sbjct: 10808 EEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPE 10867
Query: 651 ------------------------DVHLPEVQLPKVPEMKLPKMPEMAVPE-VRLPEVQL 685
DV QL +P+ K+P+ P+ VPE V L +++
Sbjct: 10868 PEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQ--VPEKVELTPLKV 10925
Query: 686 P----KVSEMKLPKVPEMAVPDVHLPEV--QLPKVCEMKVPDMKLPEIKLPKVPEMAVPD 739
P KV ++ + PE +V L V + P+ E KV KL ++K P VPE P
Sbjct: 10926 PGGEKKVRKLLPERKPE-PKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE-PPPP 10983
Query: 740 VHLPEVQLPKVS--EIRLPE-MQVPKV-PDVHLPKAPEVKLPRAPEVQLKATKAEQAEGM 795
+ EV++P V+ E ++PE +VP++ P + LP APE K P+ PE ++K K E
Sbjct: 10984 KPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLP-APEPK-PK-PEAEVKTIKPPPVEPE 11040
Query: 796 EFGFKMPKMTMPKLG-RAESPSRGKPGEAGAEVSGKLVTLPCLQP 839
P +T+P +G +AE+ + P E A+ G + +P P
Sbjct: 11041 PTPIAAP-VTVPVVGKKAEAKA---PKEEAAKPKGPIKGVPKKTP 11081
Score = 157 bits (396), Expect = 9e-38
Identities = 221/844 (26%), Positives = 340/844 (40%), Gaps = 173/844 (20%)
Query: 118 KGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAVKG 177
K P KV L + P K VP + PV V PK E K
Sbjct: 9983 KKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPV----PKKVEAPPAKVPEVPKK 10038
Query: 178 PVPA----APARRRLQLPRLRVREVA-----EEAQAARLA--AAAPPPRKAKVEAEVAAG 226
PVP PA ++++ P +V EV EE + + APPP+ K V
Sbjct: 10039 PVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVP 10098
Query: 227 ARFTAPQVELVGPRLPGAEVGVPQVSA-----PKAAPSAEAAGGFALHLPTLGLGAPAPP 281
+ L + E +P+ + P E +P P P
Sbjct: 10099 VALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVP-PE 10157
Query: 282 AVEAPAVGIQVPQVE-LPAL-PSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVD--- 336
P VP+ E LP + P +P +P ++ + VV+P + A P +
Sbjct: 10158 EEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPK 10217
Query: 337 ------LALPGAE----VEARGEAPEVALKMPRL-SFPRFGARAKEVAEAKVAKVSPEAR 385
+ LP E VE E E + + P +EVA +V +V +A
Sbjct: 10218 KVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAV 10277
Query: 386 VKGP-----RLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKVPKGP 440
+ P ++ P +S P P V+ K + P K+P + V +V VPK
Sbjct: 10278 PEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKK-EAPPAKVPEVPKKVPEKKVLVPKKE 10336
Query: 441 EVKLPKAPEVKLPKVPEAALPEVRLPE---VELPKVSEMKLPKVPEMAVPEVRLPEVELP 497
V K V KV A EV + E +E+ + ++P+ E E E E
Sbjct: 10337 AVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFH 10396
Query: 498 KVSEM---------------------------------------KLPKVPEMAVPEVRLP 518
+V E K P++ E +P + P
Sbjct: 10397 EVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPP 10456
Query: 519 -EVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKV 577
+V K K+P+VP+ V E ++ + P+V K+PEV P+ +PE ++P V
Sbjct: 10457 TKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLP---PKEVVPEKKVP-V 10512
Query: 578 PEMKVPEMKLPKVPE----------MKLPEMKLPEV---QLPKVPEMAVPDVHLPEV--- 621
P K PE PKVPE + +P K PEV ++P+VP+ AVP+ +PE
Sbjct: 10513 PPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPP 10572
Query: 622 -------QLPKVPEMKLPEMKLP----------EVKLPKVPEMAVPD--VHLPEVQLPKV 662
++P+ P+ +PE K+P VK+P+ P+ VP+ V +P + P+V
Sbjct: 10573 KPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEV 10632
Query: 663 PEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKV-------------------PEMAVPD 703
P K+P++P++AVPE ++PE +P E P+V PE A P
Sbjct: 10633 PPTKVPEVPKVAVPEKKVPEA-IPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAP- 10690
Query: 704 VHLPEVQLP---KVCEMKVPDM-----KLPEIKLPKVPEMAVPDVHLPEV--QLPKVSEI 753
P+V +P V E K P + +LP +K+P+VP+ VP+ +P V + P+
Sbjct: 10691 ---PQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPA 10747
Query: 754 RLPEMQVPKVPD--VHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGR 811
++PE+ VP+ V +PK PEV + PEV K E+ P + +P+ R
Sbjct: 10748 KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEK----------PAVPVPE--R 10795
Query: 812 AESP 815
AESP
Sbjct: 10796 AESP 10799
Score = 131 bits (330), Expect = 4e-30
Identities = 157/574 (27%), Positives = 262/574 (45%), Gaps = 45/574 (7%)
Query: 379 KVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKVP- 437
K PE V P L P P + KLK P K+P V ++++
Sbjct: 9796 KPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISI 9855
Query: 438 KGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELP 497
E + P K+P P+ + E ++P +++P+VP+ PE E E+
Sbjct: 9856 TKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVV 9915
Query: 498 KVSEMKLPKVPEMAVPEVR--LPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMK 555
E L + E + E + E +++ V +K+P+VP VPE + P V +PK E
Sbjct: 9916 THVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKP-VPVPKKKEAP 9974
Query: 556 LPEVSEV-AVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVP 614
+V EV PE ++P V +PK + K P K+P+VP+ +PE K+P V +PK ++ P
Sbjct: 9975 PAKVPEVPKKPEEKVP-VLIPK--KEKPPPAKVPEVPKKPVPEEKVP-VPVPK--KVEAP 10028
Query: 615 DVHLPEVQLPKVPEMKLP-----EMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPK 669
+PEV VPE K+P +++ P K+P+VP+ +P+ P +PK E PK
Sbjct: 10029 PAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKP-TPVPKKVEAPPPK 10087
Query: 670 MPEMAVP---EVRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQ--LPKVCEMKVPDMKL 724
+P+ P V LP+ + E +P+ + + LPE + LP+ E+ + ++
Sbjct: 10088 VPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEI 10147
Query: 725 PEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQL 784
P P+ E+ + ++PE + E LPE++ PKVP V P PE+K + E ++
Sbjct: 10148 P----PEEEEVPPEEEYVPEEEEFVPEEEVLPEVK-PKVP-VPAP-VPEIK-KKVTEKKV 10199
Query: 785 KATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVT---LPCLQPEV 841
K E+A + ++PK K P E E + ++ +P P +
Sbjct: 10200 VIPKKEEAPPAKVP-EVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSI 10258
Query: 842 DGEAHVGVPSL--TLPSVELDLPGALGLQGQVPAAKMGK---GERVEGP-----EVAAGV 891
+ V P + + + P + + + P AK+ K E+V P A V
Sbjct: 10259 EEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKV 10318
Query: 892 REVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKV 925
EV +VP +++ P+ AV +GR ++E KV
Sbjct: 10319 PEVPKKVPEKKVLVPKKEAVPPAKGR-TVLEEKV 10351
Score = 112 bits (279), Expect = 3e-24
Identities = 155/582 (26%), Positives = 247/582 (42%), Gaps = 82/582 (14%)
Query: 456 PEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEV 515
PE +P +PE +P + KV + AVPE ++P V +PK + PKVPE P+
Sbjct: 9789 PEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVP-VPIPKKLKPPPPKVPEE--PKK 9845
Query: 516 RLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLP 575
E + +++ + +V E P ++P V+E K+P + P VR+PEV
Sbjct: 9846 VFEEKIRISITKREKEQVTE---PAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 9902
Query: 576 KVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLP--EVQLPKVPEMKLPE 633
PE E ++ E L E + E + + E + +P V++P+VP +PE
Sbjct: 9903 LEPEEVAFEEEVVTHVEEYLVEEE--EEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960
Query: 634 MKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKL 693
K P V +PK E P +PEV PK PE K+P V +P+ + P + K+
Sbjct: 9961 EKKP-VPVPKKKE--APPAKVPEV--PKKPEEKVP---------VLIPKKEKPPPA--KV 10004
Query: 694 PKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVP-----DVHLPEVQLP 748
P+VP+ VP+ +P V +PK +++ P K+PE+ VPE VP V P ++P
Sbjct: 10005 PEVPKKPVPEEKVP-VPVPK--KVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVP 10061
Query: 749 KVSEIRLPEMQ----VPKVPDVHLPKAPE--------VKLPRAPEVQLKATKAEQAEGM- 795
+V + +PE + VPK + PK P+ V LP+ EV + + E +
Sbjct: 10062 EVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLP 10121
Query: 796 -------EFGFKMPKMTMPKLGRAESPSRGK---PGEAGAEVSGKLVTLPCLQPEVDGEA 845
E +P+ E P + P E + V + PEV +
Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV 10181
Query: 846 HVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVT 905
V P + + + + + P AK+ PEV V E +P E V
Sbjct: 10182 PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKV--------PEVPKKVEEKRIILPKEEEVL 10233
Query: 906 PQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAIS 965
P VE+ E E + +P S+ +P+ P + + E R +V K A+
Sbjct: 10234 P----VEVTE------EPEEEPISEEEIPE---EPPSIEEVEEVAPPRVP--EVIKKAVP 10278
Query: 966 LPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKV 1007
V + EA A + +P + +P +A P KV
Sbjct: 10279 EAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEA--PPAKV 10318
Score = 94.7 bits (234), Expect = 6e-19
Identities = 141/573 (24%), Positives = 235/573 (41%), Gaps = 60/573 (10%)
Query: 433 EVKVP-KGPEVKLPKAPEV-KLPKVPEAALPEVRLPE-----VELPKVSEMKLPKVPEMA 485
E KVP K PE K P P+V K P + + R+ E ++P+VS+ +P+ P
Sbjct: 9162 ERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRT 9221
Query: 486 VPEVRLPEVELPKVSEMKLPKVPEMAV--------PEVRLPEVQLLKVSEMKLPKVPEMA 537
+ + EV++P V K+ E V +PEVQ V+E K+ +A
Sbjct: 9222 PVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKI----HVA 9277
Query: 538 VPEVRLPEVQLPKVSEMKLPE-VSEVAVPE-VRLPEVQLPKVPEMKVPEMKLPKVPEMKL 595
+ + P ++P++ E PE V+ V +P+ V P ++P+VP+ VPE K P +
Sbjct: 9278 ISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKP------V 9331
Query: 596 PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLP 655
P K PKVPE+ V ++ +P + + P K+PEV+ V E + V
Sbjct: 9332 PVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIV--- 9388
Query: 656 EVQLPKVPEMKLPKMPEMAVPEVRLP----EVQLPKVSEMKLPKVPEMAVPDVHLPEVQL 711
Q + P +P++P+ VPE R P E ++P K+P +P+ VP+ +V +
Sbjct: 9389 -TQREESPPPAVPEIPKKKVPEERKPVPRKEEEVP--PPPKVPALPKKPVPE---EKVAV 9442
Query: 712 PKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDV-HLPK 770
P K P + K V E +P+ E+ E+ + +
Sbjct: 9443 PVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEE 9502
Query: 771 APEVKLPRAPEVQLKATKAEQAEGMEFG-FKMPK--MTMPKLGRAESPSRGKPGEAGAEV 827
+ + R E + + E+AE E+ + P+ + KL +P E
Sbjct: 9503 GVSISVYREEERE----EEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQ 9558
Query: 828 SGKLVTLPCLQPEVDGEAHVGVPSLTLPSV-ELDLPGALGLQGQVPAAKMGKGERVEGPE 886
K+V P + +++ VP V E +P + + +VP K+ + + PE
Sbjct: 9559 EKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPE 9618
Query: 887 VAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKF--SLPKFGLSGPKV- 943
+ + P VT + + EE L + K P PK + KV
Sbjct: 9619 KKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVL 9678
Query: 944 ---AKAEAEGAGRATK-----LKVSKFAISLPK 968
K E E + T+ +K K +I PK
Sbjct: 9679 KLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPK 9711
Score = 87.0 bits (214), Expect = 1e-16
Identities = 200/899 (22%), Positives = 332/899 (36%), Gaps = 189/899 (21%)
Query: 175 VKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPP-----PRKAKVEAEVAAGARF 229
V+ P P P ++P+ V E + + AAPP P+K E ++
Sbjct: 9309 VEPPAPKVP-----EVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPV-- 9361
Query: 230 TAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVG 289
A + E ++P + GV E + A+ P P + P
Sbjct: 9362 -AKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAV---------PEIPKKKVPEER 9411
Query: 290 IQVP--QVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEAR 347
VP + E+P P +P LP P E + V+V VP A P P AEV +
Sbjct: 9412 KPVPRKEEEVPPPPKVPALPKKPVPEEK---VAVPVPVAKKAPP--------PRAEVSKK 9460
Query: 348 GEAPE--------VALKMP-RLSFPRFGARAKEV--------------------AEAKVA 378
E ++ +P R+ R A+E E + A
Sbjct: 9461 TVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEA 9520
Query: 379 KVSPEARVKGPRLRMPTFGLSLLEPR-PAAPEVVESKLKLPTIKMPSLGIGVSGPE-VKV 436
+V+ ++ P + L ++ R A P V + + + P + + P KV
Sbjct: 9521 EVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKV 9580
Query: 437 PKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKL-PKVPEM----------- 484
P+ P+ +P+ +V P + +P ++PE V E K+ PKV +M
Sbjct: 9581 PEAPKKIVPEK-KVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTER 9639
Query: 485 ------------------AVPEVRLPEVELPKVSEMKLPKV-------PEMAVPEVRLPE 519
A P+ R+PE V E K+ K+ P V E R
Sbjct: 9640 HMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRV 9699
Query: 520 VQLLKVSEMKLPKVPEMAVPEVRLPE------------VQLPKVSEMKLPEVSEVAVPEV 567
V+ KVS ++ PK + EV + E V + + E + E + E
Sbjct: 9700 VKEEKVS-IEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEE 9758
Query: 568 RLPEVQLPKVPEMKVPEMKLPKVPEMKL--PEMKLPEVQLPKVPEMAVPDVHLPEVQLPK 625
P + + E + E + + E + PE +P +P+ P P +V
Sbjct: 9759 YEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKA 9818
Query: 626 VPEMKLP-----EMKLPEVKLPKVPEMAVPD-----VHLPEVQLPKVPEMKLPKMPEMAV 675
VPE K+P ++K P K+P+ P+ + + E + P K+P P+ V
Sbjct: 9819 VPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVV 9878
Query: 676 PEVRLPEVQLPKVSEMKLPKVPEMAVPD---------VHLPE------------------ 708
E ++P + +++P+VP+ P+ H+ E
Sbjct: 9879 AEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFIT 9938
Query: 709 ---------VQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSE----IRL 755
V++P+V VP+ K P + +PK E P +PEV PK E + +
Sbjct: 9939 EEEVVPVIPVKVPEVPRKPVPEEKKP-VPVPKKKE--APPAKVPEV--PKKPEEKVPVLI 9993
Query: 756 PEMQVP---KVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRA 812
P+ + P KVP+V PE K+P +++A A+ E + K+ +P +
Sbjct: 9994 PKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKV 10053
Query: 813 ESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVP 872
E+P P EV KL+ V + P + + +P AL + +V
Sbjct: 10054 EAPPAKVP-----EVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEV- 10107
Query: 873 AAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKF 931
+ + E V EV EV +P E V P+ V EE + E +V P ++
Sbjct: 10108 ---LFEEEIVPEEEVLPEEEEV---LPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEY 10160
Score = 85.5 bits (210), Expect = 3e-16
Identities = 102/336 (30%), Positives = 153/336 (45%), Gaps = 55/336 (16%)
Query: 509 EMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVR 568
E A E + +VQ E KVP VPE + P PKV +K P + ++ R
Sbjct: 9141 EEAYQEREVIQVQKEVYEESHERKVPAK-VPEKKAPPP--PKV--IKKPVIEKIEKTSRR 9195
Query: 569 LPE--VQLPKVPEM--KVPEMKLPKVP-EMKLPEMKLPEVQLPKV------------PEM 611
+ E VQ+ KVPE+ K+ K + P + ++ E+K+P V K+ E
Sbjct: 9196 MEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEE 9255
Query: 612 AVPDVHLPEVQLPKVPEMK----LPEMKLPEVKLPKVPEMAVPDVHLPEVQLPK---VPE 664
V V +PEVQ V E K + + P K+P++PE P+ P V +PK P
Sbjct: 9256 EV-SVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAP-VPIPKKVEPPA 9313
Query: 665 MKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKL 724
K+P++P+ VPE + P V +PK PKVPE+ V ++ +P + + P K+
Sbjct: 9314 PKVPEVPKKPVPEEKKP-VPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKV 9372
Query: 725 PEIKLPKVPEMAV---------PDVHLPEVQLPKVSEIRLP----EMQVPKVPDV-HLPK 770
PE++ V E + P +PE+ KV E R P E +VP P V LPK
Sbjct: 9373 PEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPK 9432
Query: 771 AP----EVKLP-----RAPEVQLKATKAEQAEGMEF 797
P +V +P +AP + + +K E F
Sbjct: 9433 KPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRF 9468
Score = 67.8 bits (164), Expect = 7e-11
Identities = 125/571 (21%), Positives = 220/571 (38%), Gaps = 103/571 (18%)
Query: 441 EVKLP-KAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKV 499
E+KL K P++ +VP +P +P E+P V +P + + PE + P + +V
Sbjct: 8927 EIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLL--LPTPEEKKPPPKRIEV 8984
Query: 500 SEMKLPKVPE--MAVPEVRLPEVQLLK----VSEMKLPKVPEMAVPEVRLPEVQLPKVSE 553
++ + K + +A P+ P +++K + + K PE+ + EV++ ++
Sbjct: 8985 TKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITR 9044
Query: 554 MKLPEVSEVAVPEVR--LPEVQLPKVPEMKVPEMKL---PKVPEMKLPEMKLPEVQLPKV 608
K + + AV E + + + + + + P +L P + P + P+ ++
Sbjct: 9045 KKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEI 9104
Query: 609 PEMAVPDVH-------------------------------------------LPEVQLPK 625
A +VH E K
Sbjct: 9105 KVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERK 9164
Query: 626 VPEMKLPEMKLPE----VKLPKVPEMAVPDVHLPE--VQLPKVPEMK---LPKMPEMAVP 676
VP K+PE K P +K P + ++ + E VQ+ KVPE+ +P+ P
Sbjct: 9165 VP-AKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPV 9223
Query: 677 EVRLPEVQLPKVSEMKLPKVPEMAV--------PDVHLPEVQLPKVCEMKV--------- 719
+ + EV++P V K+ E V +PEVQ V E K+
Sbjct: 9224 QEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVE 9283
Query: 720 PDMKLPEIKLPKVPEMAVP-----DVHLPEVQLPKVSEIRLPE----MQVPKVPDVHLPK 770
P K+PE+ PE P V P ++P+V + +PE + VPK PK
Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPK 9343
Query: 771 APEVKLPRAPEVQLKATKAEQAEG-------MEFGFKMPKMTMPKLGRAESPSRGKPGEA 823
PEV PE ++ A++ E ++ G + R ESP P
Sbjct: 9344 VPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIP 9403
Query: 824 GAEVSGKLVTLPCLQPEVDGEAHV-GVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERV 882
+V + +P + EV V +P +P ++ +P + + P A++ K V
Sbjct: 9404 KKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVV 9463
Query: 883 EGPEVAAGVREVGFRVPS-VEIVTPQLPAVE 912
E A ++ F VP VE+ ++ A E
Sbjct: 9464 EEKRFVA-EEKLSFAVPQRVEVTRHEVSAEE 9493
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 90.9 bits (224), Expect = 8e-18
Identities = 138/565 (24%), Positives = 195/565 (34%), Gaps = 60/565 (10%)
Query: 229 FTAPQVELVGPRLPGAEVGVPQVSAPK---AAPSAEAAGGFALHLPTLGLGAPAPPAVEA 285
F QV G P E +P + P A P+ + A AL P G A PA E
Sbjct: 809 FPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEG 868
Query: 286 PAVGIQVPQVELPALPSLP----TLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPG 341
AV + AL P + ++ LE + + V P V V +
Sbjct: 869 TAV--------VAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP--- 917
Query: 342 AEVEARGEAPEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLL 401
G A A+ P + P A + + VA SPE T ++
Sbjct: 918 -----EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI-----TVPITEE 967
Query: 402 EPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALP 461
+ P P + + P + + + VS PE P P +P E P P AA+P
Sbjct: 968 DGTPEGPVTPATTVHAPE-EPDTAAVRVSTPEE--PASPAAAVPTPEE---PTSPAAAVP 1021
Query: 462 EVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQ 521
P V + P P AVP P V + P P AVP P
Sbjct: 1022 TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1081
Query: 522 LLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMK 581
V + P P AVP PE + + PE E A P +P + P P
Sbjct: 1082 AAAVPTPEEPTSPAAAVPT---PEEPTSPAAAVPTPE--EPASPAAAVPTPEEPASPAAA 1136
Query: 582 VPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHL-PEVQLPKVPEMKLPEMKLPEVK 640
VP P+ P P + PE + P+ P +P E + ++
Sbjct: 1137 VPT---PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE 1193
Query: 641 LPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMA 700
P P +VP P + + E P +VP P VS + P P A
Sbjct: 1194 EPTSPAASVPT---PAAMVATLEEFT---SPAASVPTSEEPASLAAAVSNPEEPTSPAAA 1247
Query: 701 VPDVHLPEVQLPKVC---EMKVPDMKLPEIKLPKVPEMAVPDVHLP-----EVQLPKVSE 752
VP + P V E+ P +P + P P AV ++ P V P+V+
Sbjct: 1248 VPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA 1307
Query: 753 I---RLPEMQVPKVPDVHLPKAPEV 774
I +P +VP +P +P EV
Sbjct: 1308 IPAASVPTPEVPAIPAAAVPPMEEV 1332
Score = 87.0 bits (214), Expect = 1e-16
Identities = 124/494 (25%), Positives = 177/494 (35%), Gaps = 54/494 (10%)
Query: 205 ARLAAAAPPPRK-------AKVEAEVAAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAA 257
A +AA P P + +E E A +AP+ V P V VP+ +A AA
Sbjct: 870 AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATV----PAVTVSVPEGTAAVAA 925
Query: 258 PSA--EAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETR 315
S+ E A A + G+ A A + E A+ I VP E P P P
Sbjct: 926 VSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPE 985
Query: 316 E---GAVSVVVPTLDVAAPTVGV----DLALPGAEVEARGEAPEVALKMPRLSFPRFGAR 368
E AV V P + A+P V + P A V E A +P P A
Sbjct: 986 EPDTAAVRVSTPE-EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA 1044
Query: 369 AKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIG 428
A E SP A V P PT + + P E +PT + P+
Sbjct: 1045 AVPTPEEPT---SPAAAVPTPE--EPTSPAAAV---PTPEEPTSPAAAVPTPEEPT---- 1092
Query: 429 VSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPE 488
P VP E P +P +P E A P +P E P +P E A P
Sbjct: 1093 --SPAAAVPTPEE---PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA 1147
Query: 489 VRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQ-----LLKVSEMKLPKVPEMAVPEVRL 543
+P E + + +P E A P +P V+ ++ P P +VP
Sbjct: 1148 PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT--- 1204
Query: 544 PEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEV 603
P + + E P S VP P V + P VP ++ P V
Sbjct: 1205 PAAMVATLEEFTSPAAS---VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAV 1261
Query: 604 QLPKVPEMAVPDVHLPEVQLPKVPEM---KLPEMKLPEVKLPKVPEMAVPDVHLPEVQLP 660
P+ E++ P +P + P P L E P +P A+P +P ++P
Sbjct: 1262 LTPE--ELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVP 1319
Query: 661 KVPEMKLPKMPEMA 674
+P +P M E++
Sbjct: 1320 AIPAAAVPPMEEVS 1333
Score = 65.1 bits (157), Expect = 5e-10
Identities = 110/493 (22%), Positives = 159/493 (32%), Gaps = 70/493 (14%)
Query: 478 LPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMA 537
+P V + + PE E ++ + P+ + V P +L S + L + ++
Sbjct: 840 VPTVKDALDAALPSPE-EGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEE-EDVT 897
Query: 538 VPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKV----------------PEMK 581
V PE + +PE AV V PE P V PE
Sbjct: 898 AAAVSAPERATVPAVTVSVPE-GTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWA 956
Query: 582 VPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKL 641
+ +P E PE + PE PD V P+ P P +P +
Sbjct: 957 ALAITVPITEEDGTPEGPVTPATTVHAPEE--PDTAAVRVSTPEEPAS--PAAAVPTPEE 1012
Query: 642 PKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAV 701
P P AVP P VP + P P AVP P V + P P AV
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072
Query: 702 P---DVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEM 758
P + P +P E P +P + P P AVP PE + + PE
Sbjct: 1073 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP---TPEEPASPAAAVPTPEE 1129
Query: 759 QVPKVPDVHLPKAPEVKLPRAPEVQLKATKA-----------------EQAEGMEFGFKM 801
V P+ P P P + A+ A AE F +
Sbjct: 1130 PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVV 1189
Query: 802 PKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQ-----------PEVDGEAHVGVP 850
+ P A P+ E + ++P + PE VP
Sbjct: 1190 ATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP 1249
Query: 851 SLTLPS---------VELDLPGA---LGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRV 898
+L P+ EL P A + PAA + E P A EV +
Sbjct: 1250 TLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVA-AI 1308
Query: 899 PSVEIVTPQLPAV 911
P+ + TP++PA+
Sbjct: 1309 PAASVPTPEVPAI 1321
Score = 60.8 bits (146), Expect = 9e-09
Identities = 95/385 (24%), Positives = 133/385 (34%), Gaps = 72/385 (18%)
Query: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVE 235
+GPV A + P V+ + A AAA P P E + A P+
Sbjct: 972 EGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP-----EEPTSPAAAVPTPEE- 1025
Query: 236 LVGPRLPGAEVGVPQ--VSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVP 293
P P A V P+ S A P+ E A +PT P +PA + P
Sbjct: 1026 ---PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT-------PEEPTSPAAAVPTP 1075
Query: 294 QVELPALPSLPTL--PTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAP 351
+ ++PT PT P + PT AA + A P A V E
Sbjct: 1076 EEPTSPAAAVPTPEEPTSPAA----AVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPA 1131
Query: 352 EVALKMPRLSFPRFGARA----KEVAEAKVAKVSPEARVKGPRLRMPTFG--------LS 399
A +P P F A A +E A A VA +PE P +PT ++
Sbjct: 1132 SPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESAS-PAAAVPTPAESASFAAVVA 1190
Query: 400 LLE---------PRPAA-----PEVVESKLKLPTIKMP-SLGIGVSGPEVKVPKGPEVKL 444
LE P PAA E +PT + P SL VS PE P P +
Sbjct: 1191 TLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE--PTSPAAAV 1248
Query: 445 P------------------KAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAV 486
P +P +P E A P + +E P +P A+
Sbjct: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
Query: 487 PEVRLPEVELPKVSEMKLPKVPEMA 511
P +P E+P + +P + E++
Sbjct: 1309 PAASVPTPEVPAIPAAAVPPMEEVS 1333
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 88.2 bits (217), Expect = 5e-17
Identities = 135/504 (26%), Positives = 191/504 (37%), Gaps = 61/504 (12%)
Query: 345 EARGEAPEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPR 404
+A+ A E A P P KE A++ SPE + K P P
Sbjct: 549 KAKSPAKEEAKSPPEAKSPE-----KEEAKSPAEVKSPE-KAKSPAKEEAKSPAEAKSPE 602
Query: 405 PAAPEVVESKLKLPTIKMPSLGIGVSGPEVKVP---KGPEVKLPKAPE-VKLPKVPEAAL 460
A V E K P S EVK P K P + K+PE K P+ EA
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKS 662
Query: 461 PEVRLPEVELPKVSEMKLPKVPEMAVP-EVRLPE-VELPKVSEMKLPKVPEMAVPE-VRL 517
PE + + P +E K P+ + V E + PE + P E K P+ + V E +
Sbjct: 663 PE----KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718
Query: 518 PEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKV 577
PE V E K PE A V+ K + + +V PE + P + +
Sbjct: 719 PEKAKSPVKEEA--KTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS 776
Query: 578 PEMKVPEM-KLPKVPEMKLPEM---------KLPEVQLPKVPEMAVPDVHLPEVQLPKVP 627
P K PE K P E+K PE K PE ++PK E+ P + E + P+
Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP---VKEEEKPQEV 833
Query: 628 EMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPK 687
++K P K E K P P+ E + K E + P+ V E + P V+ PK
Sbjct: 834 KVKEPPKKAEEEKAPATPKTE-------EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886
Query: 688 VSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQL 747
S+++ K V PE + P E+K D K E +V + D E
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK-EDAKPKE--KTEVAKKEPDDAKAKEPSK 943
Query: 748 PKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMP 807
P + PE + K K PE K P+ + KA + ++ E + P
Sbjct: 944 PAEKKEAAPEKKDTKEEKA---KKPEEK----PKTEAKAKEDDKTLSKE-------PSKP 989
Query: 808 KLGRAESPSR-----GKPGEAGAE 826
K +AE S KP E E
Sbjct: 990 KAEKAEKSSSTDQKDSKPPEKATE 1013
Score = 66.2 bits (160), Expect = 2e-10
Identities = 123/506 (24%), Positives = 186/506 (36%), Gaps = 40/506 (7%)
Query: 173 EAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAP 232
E K P A + V+ + A+ A +PP K+ + E + A +P
Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP 581
Query: 233 QVELVGPRLPGAEVGVPQVSAPKA-APSAEAAGGFALHLPTLGLGAPAPPAVEAP--AVG 289
+ + P A+ S KA +P E A A + A +P V++P A
Sbjct: 582 E-KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS 640
Query: 290 IQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPG---AEVEA 346
+ + P P E + V + + A V + P + V+
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE 700
Query: 347 RGEAPEVALKMPRLSFPRFGARAKEVA--EAKV---AKVSPEARVKGP-RLRMPTFGLSL 400
++PE A K P + +AK EAK AK + K P + + P +L
Sbjct: 701 EAKSPEKA-KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759
Query: 401 LEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKVP---KGPEVKLPKAPEVKLPKVPE 457
P A + + + P K P EVK P K P + KAPE ++PK
Sbjct: 760 DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK--- 816
Query: 458 AALPEVRLPEVELPKVSEMKLPKVPEMAVPE-----VRLPEVELPKVSEMKLPKVPEMAV 512
EV+ P E K E+K+ + P+ A E + E + K E + P+ V
Sbjct: 817 --KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874
Query: 513 PEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEM----KLPEVSEVAVPEVR 568
E + P V+ K S+++ K +V PE + P E+ K E +EVA E
Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 569 LPEVQLPKVPEMK---VPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPK 625
+ + P P K PE K K + K PE K PK A D + K
Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK------PKTEAKAKEDDKTLSKEPSK 988
Query: 626 VPEMKLPEMKLPEVKLPKVPEMAVPD 651
K + + K K PE A D
Sbjct: 989 PKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 37.7 bits (86), Expect = 0.082
Identities = 51/205 (24%), Positives = 81/205 (39%), Gaps = 19/205 (9%)
Query: 1229 REAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNH 1288
+EA+ E EGG + GGE + PP E + +
Sbjct: 476 KEAKEEEGKEEEGGEEEEAE--------GGEEETKSPPAEEAASPEKEAKSPVKEEAKSP 527
Query: 1289 AEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEG 1348
AE + E E EA +V+ P AKE A+ +AKSP+ + S +E+ + E
Sbjct: 528 AEAKSPEKE-EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAK---SPAEVKSPEK 583
Query: 1349 SPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLA-APSKASRGQEGDAAPKSPVREKS 1407
+ SP +EE + E S + + V+ A A S + A KSP + KS
Sbjct: 584 AKSP---AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS 640
Query: 1408 P---KFRFPRVSLSPKARSGSGDQE 1429
P + + P + SP+ ++
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEK 665
Score = 32.3 bits (72), Expect = 3.4
Identities = 94/453 (20%), Positives = 162/453 (35%), Gaps = 53/453 (11%)
Query: 667 LPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPK-VCEMKVPDMKLP 725
LPK+P ++ +++ + KV E E + + E Q+ + V E + + K
Sbjct: 426 LPKIPSVST-HIKVKSEEKIKVVEKS---EKETVIVEEQTEETQVTEEVTEEEEKEAKEE 481
Query: 726 EIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAP-EVKLPRAPEV-- 782
E K + E + E + P E PE + K P K+P E K P E
Sbjct: 482 EGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA-KSPVKEEAKSPAEAKSPEKEEAKS 540
Query: 783 --QLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPE 840
++K+ + ++ E P+ P+ A+SP+ K E + + E
Sbjct: 541 PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA---------KEE 591
Query: 841 VDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPS 900
A P V+ + + V E V+ PE A + + P
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAE-VKSPEKAKSPTKEEAKSPE 650
Query: 901 VEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVS 960
+ +P+ + E ++ + K K P KAEA+ +A K V
Sbjct: 651 -KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP---------VKAEAKSPEKA-KSPVK 699
Query: 961 KFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPR 1020
+ A S KA+ + EAK +A + P+ + S E A + K K P
Sbjct: 700 EEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA-----KSPVKEEAKSPEKAKSPE 754
Query: 1021 FALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKEAEVQGDR 1080
A + D ++ E E + P K P + KE ++
Sbjct: 755 KA------KTLDVKSPEAKTPAKE----------EARSPADKFPEKAKSPVKEEVKSPEK 798
Query: 1081 ASPGEKAESTAVQLKIPEVELVTLGAQEEGRAE 1113
A K ++ A + +IP+ E V +EE + +
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831
Score = 31.6 bits (70), Expect = 5.9
Identities = 36/136 (26%), Positives = 56/136 (41%), Gaps = 15/136 (11%)
Query: 1303 KLKVRLPRFGLVRAKEGAEEGEKAKSP---KLRLPRVGFS--QSEMVTGEGSPSPEEEEE 1357
K + + P KE A+ EKAKSP + + P S + E T E + SP +EE
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 1358 EEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAAP---KSPVREKSPKFRFPR 1414
+ E + + + V+ P P+K D P KSPV+E + + P
Sbjct: 745 KSPEKAKSPEKAK--TLDVKSPEA--KTPAKEEARSPADKFPEKAKSPVKE---EVKSPE 797
Query: 1415 VSLSPKARSGSGDQEE 1430
+ SP ++E
Sbjct: 798 KAKSPLKEDAKAPEKE 813
Score = 31.2 bits (69), Expect = 7.6
Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 13/129 (10%)
Query: 1339 SQSEMVTGEGSPSPEEEEEEEE---EGSGEGASGRRGRVRVRLPRVGLAA-PSKASRGQE 1394
++ VT E + E+E +EEE E GE G + P AA P K ++
Sbjct: 461 TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV 520
Query: 1395 GDAAPKSPVREKSP---KFRFPRVSLSP-KARSGSGDQEEGGLRVRLPSVGFSETGAPGP 1450
+ A KSP KSP + + P SP KA+S + ++ + + P + A P
Sbjct: 521 KEEA-KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP----EKEEAKSP 575
Query: 1451 ARMEGAQAA 1459
A ++ + A
Sbjct: 576 AEVKSPEKA 584
Score = 31.2 bits (69), Expect = 7.6
Identities = 65/292 (22%), Positives = 100/292 (34%), Gaps = 33/292 (11%)
Query: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADL-APVDVEFSFPKFSRLRRGLKAEA 174
E K P + + ++ SP K K V P +PV E P+ ++ K
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760
Query: 175 VKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQV 234
VK P PA+ + P + E A+ + +P K+ ++ + A + +
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAK--SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818
Query: 235 ELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQ--- 291
E+ P + +V P E A P EAP ++
Sbjct: 819 EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878
Query: 292 VPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEA- 350
P VE P + + E VPT + AP A+VE + +A
Sbjct: 879 EPAVEKPKESKVEA-------KKEEAEDKKKVPTPEKEAP----------AKVEVKEDAK 921
Query: 351 ----PEVALKMP---RLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPT 395
EVA K P + P A KE A K K + E + K P + T
Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK--KDTKEEKAKKPEEKPKT 971
Score = 30.8 bits (68), Expect = 10.0
Identities = 35/140 (25%), Positives = 55/140 (39%), Gaps = 15/140 (10%)
Query: 1282 SPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSP-----------K 1330
SP E + A+ E K + P ++ A+ EKAKSP K
Sbjct: 560 SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAK 619
Query: 1331 LRLPRVGFSQSEMVTGEGSPSPEEEEEE--EEEGSGEGASGRRGRVRVRLPRVGLAAPSK 1388
+ S +E+ + E + SP +EE + E+ S E + + +P K
Sbjct: 620 SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK 679
Query: 1389 ASRGQEGDAAPKSPVREKSP 1408
A + +A KSP + KSP
Sbjct: 680 AKSPVKAEA--KSPEKAKSP 697
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 80.9 bits (198), Expect = 8e-15
Identities = 139/642 (21%), Positives = 186/642 (28%), Gaps = 49/642 (7%)
Query: 171 KAEAV-KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARF 229
KAE KGP P P+ +E + +A P++
Sbjct: 200 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP------------ 247
Query: 230 TAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVG 289
AP P P P A PT AP P AP
Sbjct: 248 -APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT- 305
Query: 290 IQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGE 349
P+ P P P PT P E PT APT + A + A
Sbjct: 306 ---PKKPAPTTPKEPA-PTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360
Query: 350 APEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPE 409
E A P+ P + A + ++ + PT S P P
Sbjct: 361 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-PTTPKEPS 419
Query: 410 VVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEV---RLP 466
+K PT P PK P PK P K P P+ P
Sbjct: 420 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 479
Query: 467 EVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEV-RLPEVQLLKV 525
+ P + P PE P PE P E P PE P P K
Sbjct: 480 KETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 537
Query: 526 SEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPE------VRLPEVQLPKVP- 578
+ PK P P+ P PK P+ + P+ ++ P PK P
Sbjct: 538 AAPNTPKEPAPTTPKEPAPTT--PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595
Query: 579 --EMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPE-MK 635
E+ K P P P+ P P+ P P+ P P+ P +K
Sbjct: 596 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPTTLK 653
Query: 636 LPEVKLPKVP---EMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMK 692
P PK P E+A P P PK P+ P PK
Sbjct: 654 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--PKKPAPT 711
Query: 693 LPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIK---LPKVPEMAVPDVHLPEVQLPK 749
P+ P +V P K PD PE+ PK E + + +P + P
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 771
Query: 750 VSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQ 791
++ + K + L PE + AT E+
Sbjct: 772 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 813
Score = 75.5 bits (184), Expect = 4e-13
Identities = 118/496 (23%), Positives = 150/496 (30%), Gaps = 74/496 (14%)
Query: 369 AKEVAEAK--VAKVSPEARV--KGPRLRMPTFGLSLLEPRPAA-----PEVVESKLKLPT 419
AK++A +AK +P+A KGP L P PA+ P K T
Sbjct: 184 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 243
Query: 420 IKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEV--ELPKVSEMK 477
K P+ S P PK P K P PK P + P P +
Sbjct: 244 PKEPAPTTTKSAPTT--PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 478 LPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMA 537
P P+ P P+ P + P P+ P + P K PK P
Sbjct: 302 APTTPKKPAPTT--PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 359
Query: 538 VPE--------------VRLPEVQLPK----VSEMKLPEVSEVAVPEVRLPEVQLPKVPE 579
P+ + P PK + P ++ P PK P
Sbjct: 360 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 419
Query: 580 ---MKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEM-KLPEMK 635
K P PK P P K P PK P P P P K P
Sbjct: 420 PTTTKEPAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 636 LPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPK 695
P+ P P+ P PE P PE P PE P PE P E P
Sbjct: 478 TPKETAPTTPKKLTPTT--PEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPT 533
Query: 696 VPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRL 755
P+ A P+ P+ P K P P+ P P+ P P+ P + ++
Sbjct: 534 TPKAAAPNT--PKEPAPTT--PKEPAPTTPKEPAPTTPKETAPTT--PKGTAP--TTLKE 585
Query: 756 PEMQVPKVP------------------DVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEF 797
P PK P D P P+ P P+ T E A
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645
Query: 798 G-----FKMPKMTMPK 808
G K P T PK
Sbjct: 646 GTAPTTLKEPAPTTPK 661
Score = 68.6 bits (166), Expect = 4e-11
Identities = 111/503 (22%), Positives = 149/503 (29%), Gaps = 46/503 (9%)
Query: 133 SPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV-KGPVPAAPARRRLQLP 191
+P KK P PA P + + PK A K P P AP + P
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361
Query: 192 RLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFT---APQVELVGPRLPG----A 244
+ +E +P K + T AP P P
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 421
Query: 245 EVGVPQVSAPK----AAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPAL 300
P + PK P A PT PAP + PA P+ P
Sbjct: 422 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAP--TTPKEPAPTT 478
Query: 301 PSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRL 360
P T PT P T + T + APT +LA E E A P+
Sbjct: 479 PK-ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 537
Query: 361 SFPRFGARAKEVAEAKVAKVSPEA------RVKGPRLRMPTFGLSLLEPRPAAPEVVESK 414
+ P + A +P+ + P T +L EP P P+ K
Sbjct: 538 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 597
Query: 415 LKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPE-VELPKV 473
PT P PKG PK P PK P P+ P ++ P
Sbjct: 598 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 657
Query: 474 SEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKV 533
+ K P E+A + P S+ P P+ P PK
Sbjct: 658 TTPKKPAPKELAPTTTKGPT---STTSDKPAPTTPKETAPTT---------------PKE 699
Query: 534 PEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEM 593
P P+ P E P SEV+ P + K P+ PE+ P+
Sbjct: 700 PAPTTPKK-----PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754
Query: 594 KLPEMKLPEVQLPKVPEMAVPDV 616
K P V K P P++
Sbjct: 755 LENSPKEPGVPTTKTPAATKPEM 777
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 80.9 bits (198), Expect = 8e-15
Identities = 139/642 (21%), Positives = 186/642 (28%), Gaps = 49/642 (7%)
Query: 171 KAEAV-KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARF 229
KAE KGP P P+ +E + +A P++
Sbjct: 241 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP------------ 288
Query: 230 TAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVG 289
AP P P P A PT AP P AP
Sbjct: 289 -APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT- 346
Query: 290 IQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGE 349
P+ P P P PT P E PT APT + A + A
Sbjct: 347 ---PKKPAPTTPKEPA-PTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401
Query: 350 APEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPE 409
E A P+ P + A + ++ + PT S P P
Sbjct: 402 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-PTTPKEPS 460
Query: 410 VVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEV---RLP 466
+K PT P PK P PK P K P P+ P
Sbjct: 461 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 520
Query: 467 EVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEV-RLPEVQLLKV 525
+ P + P PE P PE P E P PE P P K
Sbjct: 521 KETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 578
Query: 526 SEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPE------VRLPEVQLPKVP- 578
+ PK P P+ P PK P+ + P+ ++ P PK P
Sbjct: 579 AAPNTPKEPAPTTPKEPAPTT--PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636
Query: 579 --EMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPE-MK 635
E+ K P P P+ P P+ P P+ P P+ P +K
Sbjct: 637 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPTTLK 694
Query: 636 LPEVKLPKVP---EMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMK 692
P PK P E+A P P PK P+ P PK
Sbjct: 695 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--PKKPAPT 752
Query: 693 LPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIK---LPKVPEMAVPDVHLPEVQLPK 749
P+ P +V P K PD PE+ PK E + + +P + P
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 812
Query: 750 VSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQ 791
++ + K + L PE + AT E+
Sbjct: 813 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 854
Score = 75.5 bits (184), Expect = 4e-13
Identities = 118/496 (23%), Positives = 150/496 (30%), Gaps = 74/496 (14%)
Query: 369 AKEVAEAK--VAKVSPEARV--KGPRLRMPTFGLSLLEPRPAA-----PEVVESKLKLPT 419
AK++A +AK +P+A KGP L P PA+ P K T
Sbjct: 225 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 284
Query: 420 IKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEV--ELPKVSEMK 477
K P+ S P PK P K P PK P + P P +
Sbjct: 285 PKEPAPTTTKSAPTT--PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 478 LPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMA 537
P P+ P P+ P + P P+ P + P K PK P
Sbjct: 343 APTTPKKPAPTT--PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 400
Query: 538 VPE--------------VRLPEVQLPK----VSEMKLPEVSEVAVPEVRLPEVQLPKVPE 579
P+ + P PK + P ++ P PK P
Sbjct: 401 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 460
Query: 580 ---MKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEM-KLPEMK 635
K P PK P P K P PK P P P P K P
Sbjct: 461 PTTTKEPAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 636 LPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPK 695
P+ P P+ P PE P PE P PE P PE P E P
Sbjct: 519 TPKETAPTTPKKLTPTT--PEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPT 574
Query: 696 VPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRL 755
P+ A P+ P+ P K P P+ P P+ P P+ P + ++
Sbjct: 575 TPKAAAPNT--PKEPAPTT--PKEPAPTTPKEPAPTTPKETAPTT--PKGTAP--TTLKE 626
Query: 756 PEMQVPKVP------------------DVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEF 797
P PK P D P P+ P P+ T E A
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686
Query: 798 G-----FKMPKMTMPK 808
G K P T PK
Sbjct: 687 GTAPTTLKEPAPTTPK 702
Score = 68.6 bits (166), Expect = 4e-11
Identities = 111/503 (22%), Positives = 149/503 (29%), Gaps = 46/503 (9%)
Query: 133 SPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV-KGPVPAAPARRRLQLP 191
+P KK P PA P + + PK A K P P AP + P
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402
Query: 192 RLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFT---APQVELVGPRLPG----A 244
+ +E +P K + T AP P P
Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 462
Query: 245 EVGVPQVSAPK----AAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPAL 300
P + PK P A PT PAP + PA P+ P
Sbjct: 463 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAP--TTPKEPAPTT 519
Query: 301 PSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRL 360
P T PT P T + T + APT +LA E E A P+
Sbjct: 520 PK-ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 578
Query: 361 SFPRFGARAKEVAEAKVAKVSPEA------RVKGPRLRMPTFGLSLLEPRPAAPEVVESK 414
+ P + A +P+ + P T +L EP P P+ K
Sbjct: 579 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 638
Query: 415 LKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPE-VELPKV 473
PT P PKG PK P PK P P+ P ++ P
Sbjct: 639 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 698
Query: 474 SEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKV 533
+ K P E+A + P S+ P P+ P PK
Sbjct: 699 TTPKKPAPKELAPTTTKGPT---STTSDKPAPTTPKETAPTT---------------PKE 740
Query: 534 PEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEM 593
P P+ P E P SEV+ P + K P+ PE+ P+
Sbjct: 741 PAPTTPKK-----PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795
Query: 594 KLPEMKLPEVQLPKVPEMAVPDV 616
K P V K P P++
Sbjct: 796 LENSPKEPGVPTTKTPAATKPEM 818
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 80.9 bits (198), Expect = 8e-15
Identities = 139/642 (21%), Positives = 186/642 (28%), Gaps = 49/642 (7%)
Query: 171 KAEAV-KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARF 229
KAE KGP P P+ +E + +A P++
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP------------ 340
Query: 230 TAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVG 289
AP P P P A PT AP P AP
Sbjct: 341 -APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT- 398
Query: 290 IQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGE 349
P+ P P P PT P E PT APT + A + A
Sbjct: 399 ---PKKPAPTTPKEPA-PTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 453
Query: 350 APEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPE 409
E A P+ P + A + ++ + PT S P P
Sbjct: 454 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-PTTPKEPS 512
Query: 410 VVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEV---RLP 466
+K PT P PK P PK P K P P+ P
Sbjct: 513 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572
Query: 467 EVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEV-RLPEVQLLKV 525
+ P + P PE P PE P E P PE P P K
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 630
Query: 526 SEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPE------VRLPEVQLPKVP- 578
+ PK P P+ P PK P+ + P+ ++ P PK P
Sbjct: 631 AAPNTPKEPAPTTPKEPAPTT--PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 688
Query: 579 --EMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPE-MK 635
E+ K P P P+ P P+ P P+ P P+ P +K
Sbjct: 689 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPTTLK 746
Query: 636 LPEVKLPKVP---EMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMK 692
P PK P E+A P P PK P+ P PK
Sbjct: 747 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--PKKPAPT 804
Query: 693 LPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIK---LPKVPEMAVPDVHLPEVQLPK 749
P+ P +V P K PD PE+ PK E + + +P + P
Sbjct: 805 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 864
Query: 750 VSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQ 791
++ + K + L PE + AT E+
Sbjct: 865 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 906
Score = 75.5 bits (184), Expect = 4e-13
Identities = 118/496 (23%), Positives = 150/496 (30%), Gaps = 74/496 (14%)
Query: 369 AKEVAEAK--VAKVSPEARV--KGPRLRMPTFGLSLLEPRPAA-----PEVVESKLKLPT 419
AK++A +AK +P+A KGP L P PA+ P K T
Sbjct: 277 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 336
Query: 420 IKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEV--ELPKVSEMK 477
K P+ S P PK P K P PK P + P P +
Sbjct: 337 PKEPAPTTTKSAPTT--PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 394
Query: 478 LPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMA 537
P P+ P P+ P + P P+ P + P K PK P
Sbjct: 395 APTTPKKPAPTT--PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 452
Query: 538 VPE--------------VRLPEVQLPK----VSEMKLPEVSEVAVPEVRLPEVQLPKVPE 579
P+ + P PK + P ++ P PK P
Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 512
Query: 580 ---MKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEM-KLPEMK 635
K P PK P P K P PK P P P P K P
Sbjct: 513 PTTTKEPAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 636 LPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPK 695
P+ P P+ P PE P PE P PE P PE P E P
Sbjct: 571 TPKETAPTTPKKLTPTT--PEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPT 626
Query: 696 VPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRL 755
P+ A P+ P+ P K P P+ P P+ P P+ P + ++
Sbjct: 627 TPKAAAPNT--PKEPAPTT--PKEPAPTTPKEPAPTTPKETAPTT--PKGTAP--TTLKE 678
Query: 756 PEMQVPKVP------------------DVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEF 797
P PK P D P P+ P P+ T E A
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738
Query: 798 G-----FKMPKMTMPK 808
G K P T PK
Sbjct: 739 GTAPTTLKEPAPTTPK 754
Score = 68.6 bits (166), Expect = 4e-11
Identities = 111/503 (22%), Positives = 149/503 (29%), Gaps = 46/503 (9%)
Query: 133 SPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV-KGPVPAAPARRRLQLP 191
+P KK P PA P + + PK A K P P AP + P
Sbjct: 395 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454
Query: 192 RLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFT---APQVELVGPRLPG----A 244
+ +E +P K + T AP P P
Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 514
Query: 245 EVGVPQVSAPK----AAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPAL 300
P + PK P A PT PAP + PA P+ P
Sbjct: 515 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAP--TTPKEPAPTT 571
Query: 301 PSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRL 360
P T PT P T + T + APT +LA E E A P+
Sbjct: 572 PK-ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 630
Query: 361 SFPRFGARAKEVAEAKVAKVSPEA------RVKGPRLRMPTFGLSLLEPRPAAPEVVESK 414
+ P + A +P+ + P T +L EP P P+ K
Sbjct: 631 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 690
Query: 415 LKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPE-VELPKV 473
PT P PKG PK P PK P P+ P ++ P
Sbjct: 691 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 750
Query: 474 SEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKV 533
+ K P E+A + P S+ P P+ P PK
Sbjct: 751 TTPKKPAPKELAPTTTKGPT---STTSDKPAPTTPKETAPTT---------------PKE 792
Query: 534 PEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEM 593
P P+ P E P SEV+ P + K P+ PE+ P+
Sbjct: 793 PAPTTPKK-----PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847
Query: 594 KLPEMKLPEVQLPKVPEMAVPDV 616
K P V K P P++
Sbjct: 848 LENSPKEPGVPTTKTPAATKPEM 870
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 80.9 bits (198), Expect = 8e-15
Identities = 139/642 (21%), Positives = 186/642 (28%), Gaps = 49/642 (7%)
Query: 171 KAEAV-KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARF 229
KAE KGP P P+ +E + +A P++
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP------------ 381
Query: 230 TAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVG 289
AP P P P A PT AP P AP
Sbjct: 382 -APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT- 439
Query: 290 IQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGE 349
P+ P P P PT P E PT APT + A + A
Sbjct: 440 ---PKKPAPTTPKEPA-PTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 494
Query: 350 APEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPE 409
E A P+ P + A + ++ + PT S P P
Sbjct: 495 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-PTTPKEPS 553
Query: 410 VVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEV---RLP 466
+K PT P PK P PK P K P P+ P
Sbjct: 554 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613
Query: 467 EVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEV-RLPEVQLLKV 525
+ P + P PE P PE P E P PE P P K
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 671
Query: 526 SEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPE------VRLPEVQLPKVP- 578
+ PK P P+ P PK P+ + P+ ++ P PK P
Sbjct: 672 AAPNTPKEPAPTTPKEPAPTT--PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 729
Query: 579 --EMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPE-MK 635
E+ K P P P+ P P+ P P+ P P+ P +K
Sbjct: 730 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPTTLK 787
Query: 636 LPEVKLPKVP---EMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMK 692
P PK P E+A P P PK P+ P PK
Sbjct: 788 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--PKKPAPT 845
Query: 693 LPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIK---LPKVPEMAVPDVHLPEVQLPK 749
P+ P +V P K PD PE+ PK E + + +P + P
Sbjct: 846 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 905
Query: 750 VSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQ 791
++ + K + L PE + AT E+
Sbjct: 906 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 947
Score = 75.5 bits (184), Expect = 4e-13
Identities = 118/496 (23%), Positives = 150/496 (30%), Gaps = 74/496 (14%)
Query: 369 AKEVAEAK--VAKVSPEARV--KGPRLRMPTFGLSLLEPRPAA-----PEVVESKLKLPT 419
AK++A +AK +P+A KGP L P PA+ P K T
Sbjct: 318 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 377
Query: 420 IKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEV--ELPKVSEMK 477
K P+ S P PK P K P PK P + P P +
Sbjct: 378 PKEPAPTTTKSAPTT--PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 435
Query: 478 LPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMA 537
P P+ P P+ P + P P+ P + P K PK P
Sbjct: 436 APTTPKKPAPTT--PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 493
Query: 538 VPE--------------VRLPEVQLPK----VSEMKLPEVSEVAVPEVRLPEVQLPKVPE 579
P+ + P PK + P ++ P PK P
Sbjct: 494 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 553
Query: 580 ---MKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEM-KLPEMK 635
K P PK P P K P PK P P P P K P
Sbjct: 554 PTTTKEPAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 636 LPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPK 695
P+ P P+ P PE P PE P PE P PE P E P
Sbjct: 612 TPKETAPTTPKKLTPTT--PEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPT 667
Query: 696 VPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRL 755
P+ A P+ P+ P K P P+ P P+ P P+ P + ++
Sbjct: 668 TPKAAAPNT--PKEPAPTT--PKEPAPTTPKEPAPTTPKETAPTT--PKGTAP--TTLKE 719
Query: 756 PEMQVPKVP------------------DVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEF 797
P PK P D P P+ P P+ T E A
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779
Query: 798 G-----FKMPKMTMPK 808
G K P T PK
Sbjct: 780 GTAPTTLKEPAPTTPK 795
Score = 68.6 bits (166), Expect = 4e-11
Identities = 111/503 (22%), Positives = 149/503 (29%), Gaps = 46/503 (9%)
Query: 133 SPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV-KGPVPAAPARRRLQLP 191
+P KK P PA P + + PK A K P P AP + P
Sbjct: 436 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495
Query: 192 RLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFT---APQVELVGPRLPG----A 244
+ +E +P K + T AP P P
Sbjct: 496 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 555
Query: 245 EVGVPQVSAPK----AAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPAL 300
P + PK P A PT PAP + PA P+ P
Sbjct: 556 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAP--TTPKEPAPTT 612
Query: 301 PSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRL 360
P T PT P T + T + APT +LA E E A P+
Sbjct: 613 PK-ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 671
Query: 361 SFPRFGARAKEVAEAKVAKVSPEA------RVKGPRLRMPTFGLSLLEPRPAAPEVVESK 414
+ P + A +P+ + P T +L EP P P+ K
Sbjct: 672 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 731
Query: 415 LKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPE-VELPKV 473
PT P PKG PK P PK P P+ P ++ P
Sbjct: 732 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 791
Query: 474 SEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKV 533
+ K P E+A + P S+ P P+ P PK
Sbjct: 792 TTPKKPAPKELAPTTTKGPT---STTSDKPAPTTPKETAPTT---------------PKE 833
Query: 534 PEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEM 593
P P+ P E P SEV+ P + K P+ PE+ P+
Sbjct: 834 PAPTTPKK-----PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888
Query: 594 KLPEMKLPEVQLPKVPEMAVPDV 616
K P V K P P++
Sbjct: 889 LENSPKEPGVPTTKTPAATKPEM 911
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 76.3 bits (186), Expect = 2e-13
Identities = 152/619 (24%), Positives = 208/619 (33%), Gaps = 40/619 (6%)
Query: 183 PARRRLQLPRLRVREVAEEAQAARLAAAAPP-PRKAKVEAEVAAGARFTAPQVELVGPRL 241
PA R L + A +AR AP P + K + A PQV PR
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA----LRPPQV--TPPRK 290
Query: 242 PGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELP--- 298
A P S+P A PS +G A +P A PA P+ + P P
Sbjct: 291 DAAPALGPLSSSPLATPSP--SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
Query: 299 -ALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGV--DLALPGAEVEARGEAPEVAL 355
A PSL TLP+ P + S+ P + A P++ + +P + +AP L
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQ-APPSLQTIPPIQVPHSLTSPSLQAPPSPL 407
Query: 356 KMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPA--APEVVES 413
+ L A +SP R L P+ S P AP + +
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSP--RQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465
Query: 414 KLKLPTIKMPSLGIGVSGPEVKVPKGPEVKL----PKAPEVKLPKVPEAALPEVRLPEVE 469
L T P++ +S P P L P+AP L P + P ++
Sbjct: 466 SPPLQTSLSPAVS-PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 470 LPKVSEMKLP--KVPEMAVPEVRLPEVEL--PKVSEMKLPKVPEMAVPEVRLPEVQLLKV 525
P S P +P +A P ++ L P + P + P L
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
Query: 526 SEMKLPKVPEMAVPEVRLPEVQ-LPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPE 584
S + P P A P + P +Q LP L A P + LP +Q P P P
Sbjct: 585 SSIATP--PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642
Query: 585 MKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKV 644
L P + P V L + P P P VQ P P P
Sbjct: 643 SPLA-TPSPQAPNALA--VHLLQAPFSPPPS---PPVQAPFSPPASPPVSPSATPPSQAP 696
Query: 645 PEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDV 704
P +A P + +P P P A P + P +Q+P P P P
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
Query: 705 HLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVP 764
P + P + P LP L K P A P + P +Q P Q P P
Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG-QAPFSP 815
Query: 765 DVHLPKAP-EVKLPRAPEV 782
LP +P P+AP V
Sbjct: 816 SASLPMSPLATPPPQAPPV 834
Score = 70.5 bits (171), Expect = 1e-11
Identities = 117/468 (25%), Positives = 166/468 (35%), Gaps = 70/468 (14%)
Query: 233 QVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQV 292
Q L P P + + +P ++P +H P L + A + +AP + +
Sbjct: 458 QAPLSLPASPPLQTSLSPAVSPLSSP-------LTIH-PLQALSSLASHSPQAPLSSLIM 509
Query: 293 PQVELPALPSLPTLPTLPCLETR---EGAVSVVVPTLDVA-APTVGVDLALPGAEVEARG 348
P +E + + P+L T P T E S+ P L A AP L P
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569
Query: 349 EAPEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLS-LLEPRPAA 407
+AP L P P + A +A A SP P +P+ LS L P P A
Sbjct: 570 QAPPSPLTTPPPETP--SSIATPPPQAPPALASP------PLQGLPSPPLSPLATPPPQA 621
Query: 408 PEVVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPE 467
P L LP ++ P + P + P + P A V L + P + P P
Sbjct: 622 PPX----LALPPLQAPPSP--PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS---PP 672
Query: 468 VELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSE 527
V+ P S P V A P + P P +A P +++P
Sbjct: 673 VQAP-FSPPASPPVSPSATPPSQAP---------------PSLAAPPLQVPPSPPASPPM 716
Query: 528 MKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEV------QLPKVPEMK 581
P A P + P +Q+P S P +S A P R+P + Q+P P
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPP-SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS 775
Query: 582 VPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKL 641
+P L K P P + P +Q P + P Q P P LP L
Sbjct: 776 LPMSPLAKPPPQAPPALATPPLQALPSPPASFPG------QAPFSPSASLPMSPLATP-- 827
Query: 642 PKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVS 689
P A P + P +Q+P P P P + P R P P S
Sbjct: 828 ---PPQAPPVLAAPLLQVPPSP----PASPTLQAP--RRPPTPGPDTS 866
Score = 32.0 bits (71), Expect = 4.5
Identities = 49/200 (24%), Positives = 64/200 (32%), Gaps = 34/200 (17%)
Query: 1255 RVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLP----- 1309
R GG G P A R P S N A A G GE K P
Sbjct: 61 RAGGIGGATIPESAPRAG----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
Query: 1310 --------------RFGL-VRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEE 1354
+ GL + A+E G+ ++PK G + G+PSP
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 1355 EEEEEEEGSGEG----ASGRRGRVRVRLPRVGLAAPSKASRGQEGDAAPKSP------VR 1404
G+ G A R R PR +++ S+ S + AA + P R
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 1405 EKSPKFRFPRVSLSPKARSG 1424
S LS ARSG
Sbjct: 237 PASRSLSSSATPLSSPARSG 256
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 75.9 bits (185), Expect = 3e-13
Identities = 146/671 (21%), Positives = 246/671 (36%), Gaps = 74/671 (11%)
Query: 148 PADLAPVDVEFSFPKFSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARL 207
P ++A +E F S ++ + A++++ V RR P L+ +E ++ +
Sbjct: 507 PDEVAQEMIESGFFHESDVK--IVAKSIRDRVALIQWRRERIWPALQPKE-QQDVGSPDK 563
Query: 208 AAAAPPPRKAKVEAEVAAGARFTAPQVE------LVGPRLPGAEVGVPQVSAPKAAPSAE 261
A P P + +V AG E L+ P LP + + S + +
Sbjct: 564 ARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGST 623
Query: 262 AAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSV 321
++ LG+ A A P E P LP +LP+L + A +
Sbjct: 624 VYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQ--SLPSLGAYQQPTAAPGL 681
Query: 322 VVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRLSFPRFGARAKEVAEAKVAKVS 381
V ++ A + P + P + MP + +
Sbjct: 682 PVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP----------------TGPGQPA 725
Query: 382 PEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKVPKGPE 441
P + + P L PT +L P+P P + LP P+ +G P P
Sbjct: 726 PPGQ-QPPPLAQPTPLPQVLAPQPVVP-LQPVPPHLPPYLAPASQVGA--PAQLKP---- 777
Query: 442 VKLPKAPEVKLPKVPEAALPEVRLPEVEL--------PKVSEMKLPKVPEMAVPEVRLPE 493
+++P+AP L +VP P +P + P + ++ VP + P+ P
Sbjct: 778 LQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPA 837
Query: 494 VELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSE 553
V LP ++ P P + + V+LP ++ VP A + L V P V+
Sbjct: 838 VILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPN-APATIPLLAVAPPGVAA 896
Query: 554 MKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKL--PEVQLPKVPEM 611
+ + AV ++ V P+M ++ P P + M+ P+ LP P +
Sbjct: 897 LSIHS----AVAQLPGQPVYPAAFPQMAPTDV--PPSPHHTVQNMRATPPQPALPPQPTL 950
Query: 612 AVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMP 671
V P+ LP P + + P+ LP P + V P+ LP PE P +P
Sbjct: 951 PPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLP 1010
Query: 672 EMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPK 731
E A P P Q+ + P ++A +P V +P + P LPE+ LP
Sbjct: 1011 EQAAP-AATPGSQI--LLGHPAPYAVDVA---AQVPTVPVPPAAVLSPP---LPEVLLPA 1061
Query: 732 VPEM------AVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLK 785
PE+ ++ V +P + LP P LP P + P P VQL
Sbjct: 1062 APELLPQFPSSLATVSASVQSVPTQTATLLPPANPP------LPGGPGIASP-CPTVQLT 1114
Query: 786 ATKAEQAEGME 796
++ + +
Sbjct: 1115 VEPVQEEQASQ 1125
Score = 37.4 bits (85), Expect = 0.11
Identities = 46/139 (33%), Positives = 56/139 (40%), Gaps = 20/139 (14%)
Query: 140 MVPGALGVPADLAPVDVEFSFPKFSRLRR------------GLKAEAVKGPVPAAPARRR 187
M PG PA +A + + P R R GL+A GP P P +RR
Sbjct: 15 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRR 74
Query: 188 LQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPRLPGAE-- 245
+ L R +AE A+ R AA AP A V A GA A E VG + PG +
Sbjct: 75 VLLLCKTRRLIAERAR-GRPAAPAP---AALVAQPGAPGAPADAGP-EPVGTQEPGPDPI 129
Query: 246 -VGVPQVSAPKAAPSAEAA 263
V AP P EAA
Sbjct: 130 AAAVETAPAPDGGPREEAA 148
Score = 30.8 bits (68), Expect = 10.0
Identities = 42/160 (26%), Positives = 62/160 (38%), Gaps = 20/160 (12%)
Query: 245 EVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLP 304
+ P+ P AP G P LG PAP + A + + +LP+ P P
Sbjct: 1467 DASAPREPLPPPAPEPSPHSG----TPQPALGQPAP-LLPAAVGAVSLATSQLPSPPLGP 1521
Query: 305 TLPTLP--CLET-------REGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEV-- 353
T+P P LE+ R G V + +LD T+ +P + A G EV
Sbjct: 1522 TVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASA-GTPVEVGD 1580
Query: 354 ---ALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPR 390
L+ R PR ++A V K + RV+ P+
Sbjct: 1581 RDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1620
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 72.4 bits (176), Expect = 3e-12
Identities = 206/838 (24%), Positives = 337/838 (40%), Gaps = 134/838 (15%)
Query: 405 PAAPEVVESKLKLPTIKMPSLGIG-VSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEV 463
P+ P V E ++ + G+G +SG +P G ++ + L +P + E
Sbjct: 929 PSTPTVGELPSGAEILEGSASGVGDLSG----LPSGEVLETSASGVGDLSGLPSGEVLET 984
Query: 464 RLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVR----LPE 519
P VE + +P V E P VE +S + +V E P V LP
Sbjct: 985 TAPGVE-------DISGLPSGEVLETTAPGVE--DISGLPSGEVLETTAPGVEDISGLPS 1035
Query: 520 VQLLKVSEMKLPKVPEMA-VPEVRLPEVQLPKVSEMK-LP--EVSEVAVPEVRLPEVQLP 575
++L E P V +++ +P + E P V ++ LP EV E P V +
Sbjct: 1036 GEVL---ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVE----DIS 1088
Query: 576 KVPEMKVPEMKLPKVPEMK-LPEMKLPEVQLPKVPEMA-VPDVHLPEVQLPKVPEMK-LP 632
+P +V E P V ++ LP ++ E P V +++ +P + E P V ++ LP
Sbjct: 1089 GLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP 1148
Query: 633 EMKLPEVKLPKVPEMA-VPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQ----LP- 686
++ E P V +++ +P + E P V ++ +P V E P V+ LP
Sbjct: 1149 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS--GLPSGEVLETAAPGVEDISGLPS 1206
Query: 687 -KVSEMKLPKVPEMA-VPDVHLPEVQLPKVCEMK-VPDMKLPEIKLPKVPEMA-VPDVHL 742
+V E P V +++ +P + E P V ++ +P ++ E P V +++ +P +
Sbjct: 1207 GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1266
Query: 743 PEVQLPKVSEIR-LPEMQVPKVPDVHLPKAPEVK-LPRAPEVQLKATKAEQAEGMEFGFK 800
E P V +I LP +V + P E+ LP ++ A ++ G+ G +
Sbjct: 1267 LETAAPGVEDISGLPSGEVLETT---APGVEEISGLPSGEVLETTAPGVDEISGLPSG-E 1322
Query: 801 MPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLT-LPSVEL 859
+ + T P + G+ E G L LP EV + GV ++ LPS E+
Sbjct: 1323 VLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPS-GGEVLEISVSGVEDISGLPSGEV 1381
Query: 860 DLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLE 919
A G++ +++ GE +E A+GV ++ R+PS E E
Sbjct: 1382 VETSASGIED---VSELPSGEGLETS--ASGVEDLS-RLPSGE----------------E 1419
Query: 920 MIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKG 979
++E S G G + + +E T L LP R G E A G
Sbjct: 1420 VLEISASGFGDLSGLPSGGEGLETSASEV-----GTDLS------GLPSGREGLETSASG 1468
Query: 980 AG--------------------EAGLLPALDLSIPQLSLDAHLPSG-KVEVAGADLKFKG 1018
A + G LP+ L Q + LPSG E +G DL G
Sbjct: 1469 AEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLG-SG 1527
Query: 1019 PRFALPKFG--------VRGRDTEAAELVPG--VAELEGKGW-GWDGRVKMPKLKMPSFG 1067
P LP F V D+ E+V +ELEG+G G G ++ L
Sbjct: 1528 PPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELD 1587
Query: 1068 LARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGM-QLSGL 1126
++ G+ + + G+ + S V +IP L + Q G + + SG+ +LSGL
Sbjct: 1588 IS-GRASGLPSGTELSGQASGSPDVSGEIP--GLFGVSGQPSGFPDTSGETSGVTELSGL 1644
Query: 1127 KVSTAGQVVTEGHDAGL---RMPPLGISLPQVELTGFGE-----AGTPG-QQAQSTVP 1175
++GQ G +G+ P GI+ E +G + +G PG A S VP
Sbjct: 1645 ---SSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVP 1699
>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
Length = 2317
Score = 72.4 bits (176), Expect = 3e-12
Identities = 206/838 (24%), Positives = 337/838 (40%), Gaps = 134/838 (15%)
Query: 405 PAAPEVVESKLKLPTIKMPSLGIG-VSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEV 463
P+ P V E ++ + G+G +SG +P G ++ + L +P + E
Sbjct: 929 PSTPTVGELPSGAEILEGSASGVGDLSG----LPSGEVLETSASGVGDLSGLPSGEVLET 984
Query: 464 RLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVR----LPE 519
P VE + +P V E P VE +S + +V E P V LP
Sbjct: 985 TAPGVE-------DISGLPSGEVLETTAPGVE--DISGLPSGEVLETTAPGVEDISGLPS 1035
Query: 520 VQLLKVSEMKLPKVPEMA-VPEVRLPEVQLPKVSEMK-LP--EVSEVAVPEVRLPEVQLP 575
++L E P V +++ +P + E P V ++ LP EV E P V +
Sbjct: 1036 GEVL---ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVE----DIS 1088
Query: 576 KVPEMKVPEMKLPKVPEMK-LPEMKLPEVQLPKVPEMA-VPDVHLPEVQLPKVPEMK-LP 632
+P +V E P V ++ LP ++ E P V +++ +P + E P V ++ LP
Sbjct: 1089 GLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP 1148
Query: 633 EMKLPEVKLPKVPEMA-VPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQ----LP- 686
++ E P V +++ +P + E P V ++ +P V E P V+ LP
Sbjct: 1149 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS--GLPSGEVLETAAPGVEDISGLPS 1206
Query: 687 -KVSEMKLPKVPEMA-VPDVHLPEVQLPKVCEMK-VPDMKLPEIKLPKVPEMA-VPDVHL 742
+V E P V +++ +P + E P V ++ +P ++ E P V +++ +P +
Sbjct: 1207 GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1266
Query: 743 PEVQLPKVSEIR-LPEMQVPKVPDVHLPKAPEVK-LPRAPEVQLKATKAEQAEGMEFGFK 800
E P V +I LP +V + P E+ LP ++ A ++ G+ G +
Sbjct: 1267 LETAAPGVEDISGLPSGEVLETT---APGVEEISGLPSGEVLETTAPGVDEISGLPSG-E 1322
Query: 801 MPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLT-LPSVEL 859
+ + T P + G+ E G L LP EV + GV ++ LPS E+
Sbjct: 1323 VLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPS-GGEVLEISVSGVEDISGLPSGEV 1381
Query: 860 DLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLE 919
A G++ +++ GE +E A+GV ++ R+PS E E
Sbjct: 1382 VETSASGIED---VSELPSGEGLETS--ASGVEDLS-RLPSGE----------------E 1419
Query: 920 MIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKG 979
++E S G G + + +E T L LP R G E A G
Sbjct: 1420 VLEISASGFGDLSGLPSGGEGLETSASEV-----GTDLS------GLPSGREGLETSASG 1468
Query: 980 AG--------------------EAGLLPALDLSIPQLSLDAHLPSG-KVEVAGADLKFKG 1018
A + G LP+ L Q + LPSG E +G DL G
Sbjct: 1469 AEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLG-SG 1527
Query: 1019 PRFALPKFG--------VRGRDTEAAELVPG--VAELEGKGW-GWDGRVKMPKLKMPSFG 1067
P LP F V D+ E+V +ELEG+G G G ++ L
Sbjct: 1528 PPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELD 1587
Query: 1068 LARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGM-QLSGL 1126
++ G+ + + G+ + S V +IP L + Q G + + SG+ +LSGL
Sbjct: 1588 IS-GRASGLPSGTELSGQASGSPDVSGEIP--GLFGVSGQPSGFPDTSGETSGVTELSGL 1644
Query: 1127 KVSTAGQVVTEGHDAGL---RMPPLGISLPQVELTGFGE-----AGTPG-QQAQSTVP 1175
++GQ G +G+ P GI+ E +G + +G PG A S VP
Sbjct: 1645 ---SSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVP 1699
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 67.8 bits (164), Expect = 7e-11
Identities = 126/514 (24%), Positives = 205/514 (39%), Gaps = 53/514 (10%)
Query: 361 SFPRFGARAKEVA-EAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPT 419
SF +F + VA E P + P + + +S+ P E ++ K
Sbjct: 154 SFLKFDSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAE 213
Query: 420 IKMPSLGIGVSGPEVKVPKGPEVKLPK-------APEVKLPKVPEAALPEVRLPEVELPK 472
+ + S + E V PE + K AP V +++ P V + VE
Sbjct: 214 LSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTM-SVEYQM 272
Query: 473 VSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPK 532
S +K + ++ L E + KV E V P PE + M P+
Sbjct: 273 KSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTS--TTMDFPE 330
Query: 533 VPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPE 592
A+ +RLPE + SE+ S + P+ LPE LPK +++ E + E
Sbjct: 331 --SSAIEALRLPEQPVDVPSEIA---DSSMTRPQ-ELPE--LPKTTALELQESSVASAME 382
Query: 593 MK-LPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPD 651
+ P +PE+Q P V P + LP VPE+ P + P +LP P AVP+
Sbjct: 383 LPGPPATSMPELQGPPV----TPVLELPGPSATPVPELPGP-LSTPVPELPGPPATAVPE 437
Query: 652 VHLPEV--------QLPKVPEMKLPKMPEMAVPEVRLPEVQLPKV----SEMKLPKVPEM 699
+ P V +LP +P + P VPE + +LP + + ++LP+ P +
Sbjct: 438 LPGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAV 497
Query: 700 AVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQ 759
V + L E Q E++ P + + ++ P PE+ L + + V E LP
Sbjct: 498 TVA-MELTE-QPVTTTELEQP-VGMTTVEHPGHPEVTTATGLLGQPEATMVLE--LPGQP 552
Query: 760 VPKVPDVHLPKAPEVK-LPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRG 818
V + LP P V +P P + AT+A + G ++ P + G
Sbjct: 553 VATTA-LELPGQPSVTGVPELPGLP-SATRALELSGQPVATGALELPGPLMAAGALEFSG 610
Query: 819 KPGEAGA-EVSGKLVTLPCLQ-------PEVDGE 844
+ G AGA E+ G+ + L+ PE+ G+
Sbjct: 611 QSGAAGALELLGQPLATGVLELPGQPGAPELPGQ 644
Score = 34.7 bits (78), Expect = 0.69
Identities = 85/354 (24%), Positives = 123/354 (34%), Gaps = 68/354 (19%)
Query: 129 IQSLSPVKKKKMVPGALGVPADLAPVDV--------EFSFPKFSR---LRRGLKAEAVKG 177
I + P K + P V + P +V FP+ S LR + V
Sbjct: 289 IMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPS 348
Query: 178 PVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELV 237
+ + R +LP L + A E Q + +A+A P G T P +EL
Sbjct: 349 EIADSSMTRPQELPELP-KTTALELQESSVASAMELPGPPATSMPELQGPPVT-PVLELP 406
Query: 238 GP------RLPGA-EVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGI 290
GP LPG VP++ P A E G +P L P PA P++G+
Sbjct: 407 GPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPA---PSMGL 463
Query: 291 QVPQV---------ELPALPSLPTLPTLP-------CLETREGAVS-------------- 320
+ PQ ELP LP + LP +E E V+
Sbjct: 464 EPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQPVTTTELEQPVGMTTVE 523
Query: 321 ------VVVPTLDVAAPTVGVDLALPGAEV-----EARGEAPEVALKMPRLSFPRFGARA 369
V T + P + L LPG V E G+ P V +P L RA
Sbjct: 524 HPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQ-PSVT-GVPELPGLPSATRA 581
Query: 370 KEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMP 423
E++ VA + E + GP + S A E++ L +++P
Sbjct: 582 LELSGQPVATGALE--LPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELP 633
Score = 31.6 bits (70), Expect = 5.9
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 9/95 (9%)
Query: 249 PQVSAPKAAPSA--EAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLPTL 306
P ++AP+++ A E++ L T+ + + V P+V + VP+ + A P T+
Sbjct: 1347 PAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSV-VTVPEPPVVAEPDYVTI 1405
Query: 307 PTL------PCLETREGAVSVVVPTLDVAAPTVGV 335
P P + E AVSV+ P++ V+ P+V V
Sbjct: 1406 PVPVVSALEPSVPVLEPAVSVLQPSMIVSEPSVSV 1440
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 67.8 bits (164), Expect = 7e-11
Identities = 126/514 (24%), Positives = 205/514 (39%), Gaps = 53/514 (10%)
Query: 361 SFPRFGARAKEVA-EAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPT 419
SF +F + VA E P + P + + +S+ P E ++ K
Sbjct: 154 SFLKFDSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAE 213
Query: 420 IKMPSLGIGVSGPEVKVPKGPEVKLPK-------APEVKLPKVPEAALPEVRLPEVELPK 472
+ + S + E V PE + K AP V +++ P V + VE
Sbjct: 214 LSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTM-SVEYQM 272
Query: 473 VSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPK 532
S +K + ++ L E + KV E V P PE + M P+
Sbjct: 273 KSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTS--TTMDFPE 330
Query: 533 VPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPE 592
A+ +RLPE + SE+ S + P+ LPE LPK +++ E + E
Sbjct: 331 --SSAIEALRLPEQPVDVPSEIA---DSSMTRPQ-ELPE--LPKTTALELQESSVASAME 382
Query: 593 MK-LPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPD 651
+ P +PE+Q P V P + LP VPE+ P + P +LP P AVP+
Sbjct: 383 LPGPPATSMPELQGPPV----TPVLELPGPSATPVPELPGP-LSTPVPELPGPPATAVPE 437
Query: 652 VHLPEV--------QLPKVPEMKLPKMPEMAVPEVRLPEVQLPKV----SEMKLPKVPEM 699
+ P V +LP +P + P VPE + +LP + + ++LP+ P +
Sbjct: 438 LPGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAV 497
Query: 700 AVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQ 759
V + L E Q E++ P + + ++ P PE+ L + + V E LP
Sbjct: 498 TVA-MELTE-QPVTTTELEQP-VGMTTVEHPGHPEVTTATGLLGQPEATMVLE--LPGQP 552
Query: 760 VPKVPDVHLPKAPEVK-LPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRG 818
V + LP P V +P P + AT+A + G ++ P + G
Sbjct: 553 VATTA-LELPGQPSVTGVPELPGLP-SATRALELSGQPVATGALELPGPLMAAGALEFSG 610
Query: 819 KPGEAGA-EVSGKLVTLPCLQ-------PEVDGE 844
+ G AGA E+ G+ + L+ PE+ G+
Sbjct: 611 QSGAAGALELLGQPLATGVLELPGQPGAPELPGQ 644
Score = 34.7 bits (78), Expect = 0.69
Identities = 85/354 (24%), Positives = 123/354 (34%), Gaps = 68/354 (19%)
Query: 129 IQSLSPVKKKKMVPGALGVPADLAPVDV--------EFSFPKFSR---LRRGLKAEAVKG 177
I + P K + P V + P +V FP+ S LR + V
Sbjct: 289 IMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPS 348
Query: 178 PVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELV 237
+ + R +LP L + A E Q + +A+A P G T P +EL
Sbjct: 349 EIADSSMTRPQELPELP-KTTALELQESSVASAMELPGPPATSMPELQGPPVT-PVLELP 406
Query: 238 GP------RLPGA-EVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGI 290
GP LPG VP++ P A E G +P L P PA P++G+
Sbjct: 407 GPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPA---PSMGL 463
Query: 291 QVPQV---------ELPALPSLPTLPTLP-------CLETREGAVS-------------- 320
+ PQ ELP LP + LP +E E V+
Sbjct: 464 EPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQPVTTTELEQPVGMTTVE 523
Query: 321 ------VVVPTLDVAAPTVGVDLALPGAEV-----EARGEAPEVALKMPRLSFPRFGARA 369
V T + P + L LPG V E G+ P V +P L RA
Sbjct: 524 HPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQ-PSVT-GVPELPGLPSATRA 581
Query: 370 KEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMP 423
E++ VA + E + GP + S A E++ L +++P
Sbjct: 582 LELSGQPVATGALE--LPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELP 633
Score = 31.6 bits (70), Expect = 5.9
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 9/95 (9%)
Query: 249 PQVSAPKAAPSA--EAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLPTL 306
P ++AP+++ A E++ L T+ + + V P+V + VP+ + A P T+
Sbjct: 1347 PAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSV-VTVPEPPVVAEPDYVTI 1405
Query: 307 PTL------PCLETREGAVSVVVPTLDVAAPTVGV 335
P P + E AVSV+ P++ V+ P+V V
Sbjct: 1406 PVPVVSALEPSVPVLEPAVSVLQPSMIVSEPSVSV 1440
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 66.2 bits (160), Expect = 2e-10
Identities = 145/590 (24%), Positives = 201/590 (34%), Gaps = 96/590 (16%)
Query: 212 PPPRKAKVEAEVAAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLP 271
PP A + AAGA P E G + GA + P+ SAP+A P+ + P
Sbjct: 37 PPVTPAALRVLGAAGAVGRKPLAERAGG-IGGATI--PE-SAPRAGPTRTSRP------P 86
Query: 272 TLGLGAPAPPA-------VEAPA-------------VGIQVPQVELPALPSLPTLPTLPC 311
G G APPA V +P G+++ E A P
Sbjct: 87 ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 146
Query: 312 LETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRLSF----PRFGA 367
L GA D + PT G P +R EV L P S P G
Sbjct: 147 LSA--GA------RRDTSGPTPGTPS--PAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 368 R--AKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSL 425
R +E + SP AR R P+ G L P + + L P PS
Sbjct: 197 RKSVSSASEHSTTEPSPAAR------RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 426 -GIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEA-ALPEVRLPEVELPKVSEMKLPKVPE 483
G + PK ++ + P+V P+ A AL + + P S P P
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310
Query: 484 MAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRL 543
++ + P P + L P + LP L S + P P A P + L
Sbjct: 311 -SLQTLPSPPATPPSQATTSLGS-PTLQATHSFLPSPPL---SPLATP--PPQAPPALAL 363
Query: 544 PEVQLPKVSEMKLPEVSEVAVPEVRLPE------------------VQLPKVPEMKVPEM 585
P +Q P S P +S +A P + P VQ P P P
Sbjct: 364 PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422
Query: 586 KLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVP 645
P P + P +Q+P P A P + P+ P P + P ++L K P
Sbjct: 423 PSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATPPPQAP----PPLAAPPLQLAKPP 477
Query: 646 EMAVPDVHLPEVQ-LPKVPEM---KLPKMPEMAVP--EVRLPEVQLPKVSEMKLPKVPEM 699
A P + P +Q LP P + P P ++P + P Q P V L +VP
Sbjct: 478 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 537
Query: 700 AVPDVHLPEVQLPKVCEMKVPDMKL--PEIKLPKVPEMAVPDVHLPEVQL 747
P +Q P+ PD + P + L P P P L
Sbjct: 538 PPAS---PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584
Score = 38.1 bits (87), Expect = 0.063
Identities = 128/582 (21%), Positives = 195/582 (33%), Gaps = 98/582 (16%)
Query: 655 PEVQLPK---VPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVP----EMAVPDVHLP 707
P+V P+ P + +A P P S LP P A + P
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 333
Query: 708 EVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPK-------VSEIRLPEMQV 760
+Q +P L + P P A P + LP +Q P +S + P Q
Sbjct: 334 TLQ---ATHSFLPSPPLSPLATP--PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388
Query: 761 PKVPDVHL-------PKAPEVKL----PRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKL 809
P VHL P +P V+ P +P V AT QA + P
Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448
Query: 810 GRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPG--ALGL 867
SPS P +A ++ + L P+ A P LPS PG
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSP 507
Query: 868 QGQVPAAKMGKGERVEGPEVAAGVREVGFRVP-SVEIVTPQLPA-----VEIEEGRLEMI 921
+P + + P +AA + +V P S + P+ P + RL +
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567
Query: 922 ETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAG 981
P P LSGP +A S A S P+ G ++ +G
Sbjct: 568 LAPGPPPPPSRSPSSTLSGPDLAGH-------------SSSATSTPEELRGYDSGPEGGA 614
Query: 982 EAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPG 1041
A P +L+ + + P+ + GA P LP G +A+ +
Sbjct: 615 AASPPPDAELAACHPAAWSRGPAPPLAFRGA------PGAPLPWPPATG--PGSADGLCT 666
Query: 1042 VAELEGKGWGWDGRVKMPKLKMPSFG-LARGKEAEVQGDRASPGEKAESTAVQLKIPEVE 1100
+ E EG P+ P+ G L G G +A+ G A +++ K +
Sbjct: 667 IYETEG-----------PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 715
Query: 1101 LVTLGAQEE-------------GRAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPP 1147
+ LGA + AEGA SG G + G VT G A
Sbjct: 716 ELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE----GGGVTGGARA------ 765
Query: 1148 LGISLPQVELTGFGEAGTPGQQAQSTVPSAEGTAGYRVQVPQ 1189
+L EL + E +P ++++++ S + V PQ
Sbjct: 766 ---ALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQ 804
Score = 32.0 bits (71), Expect = 4.5
Identities = 48/200 (24%), Positives = 69/200 (34%), Gaps = 14/200 (7%)
Query: 1239 GEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDV---ELSPSGGNHAEYQVAE 1295
G G + P +GG E P A T P E +P N + V+
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS 107
Query: 1296 GEGEAGHKLKVRLPRFGL-VRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEE 1354
+G L + GL + A+E G+ ++PK G + G+PSP
Sbjct: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 167
Query: 1355 EEEEEEEGSGEG----ASGRRGRVRVRLPRVGLAAPSKASRGQEGDAAPKSP------VR 1404
G+ G A R R PR +++ S+ S + AA + P R
Sbjct: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 227
Query: 1405 EKSPKFRFPRVSLSPKARSG 1424
S LS ARSG
Sbjct: 228 PASRSLSSSATPLSSPARSG 247
>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
Length = 1035
Score = 65.9 bits (159), Expect = 3e-10
Identities = 153/656 (23%), Positives = 255/656 (38%), Gaps = 120/656 (18%)
Query: 191 PRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPRLPGAEVGVP- 249
P RV + E +++ P P + V + R P+ ++ L E GV
Sbjct: 191 PETRVSCLPPEPPKTPVSSLRPEPPETGV-----SHLRPQPPKTQVSSLHLEPPETGVSH 245
Query: 250 --------QVSAPKAAPSAEAAGGFALHLPTLGLG--APAPPAVEAPAVGIQVPQVELPA 299
QVS+ P L P G+ P PP + + P+ +P
Sbjct: 246 LRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPD 305
Query: 300 LPSLPTLPTLPCL--ETREGAVS--------VVVPTLDVAAPTVGVDLALPGAEVEA--- 346
L P + L E E VS +V +L P GV P
Sbjct: 306 LCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSP 365
Query: 347 -RGEAPEVAL-----KMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLS- 399
R PE + + P+ P + + + P+ R+ R P G+S
Sbjct: 366 LRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSH 425
Query: 400 -LLEP--------RPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKV----PKGPEVKL-- 444
LEP RP PE S L+ K + + PE V P+ PE +
Sbjct: 426 LCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSH 485
Query: 445 --PKAPEVKL----PKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPK 498
P+ P+ + P+ P+ + +R PE VS ++ P+ P++ V + E
Sbjct: 486 LRPEPPDTGVSHLCPEPPKTRVSHLR-PEPSETGVSHLR-PEPPKILVSSLHQAPPE-SS 542
Query: 499 VSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPE 558
VS ++ P+ PE V +R PE ++ ++ P+ P+ V + PE +VS + PE
Sbjct: 543 VSHLR-PEPPETGVSHLR-PEPPKTRMYSLR-PEPPDTGVSHL-CPEPPKTRVSSLP-PE 597
Query: 559 VSEVAV-------PEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQ------- 604
E V PE R+ ++ P+ PE V ++ P+ P+ ++ ++ PE
Sbjct: 598 PPETGVSHLCPEPPETRVSHLR-PEPPETGVSHLR-PEPPKTRMYSLR-PEPPNTGVSHL 654
Query: 605 LPKVPEMAVPDV--HLPEVQL----PKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQ 658
P+ P+ V + PE + P+ PE ++ ++ P+ PE V +H PE
Sbjct: 655 CPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLR------PEPPETGVSRLH-PEPP 707
Query: 659 LPKV-------PEMKL----PKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHLP 707
+V PE ++ P+ PE V +R PE P+VS ++ P+ E V +
Sbjct: 708 KTRVSSLHAEPPESRVSHLCPEPPETGVSHLR-PEPPKPRVSSLR-PEPLETRVSHLR-- 763
Query: 708 EVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKV 763
P+ E V + P++P+ V +HL + +VS +RL + +V
Sbjct: 764 ----PEPPETGVSHLH------PELPKPRVSSLHLEPPKTRRVSSLRLEPPKTGRV 809
Score = 51.2 bits (121), Expect = 7e-06
Identities = 127/534 (23%), Positives = 214/534 (40%), Gaps = 92/534 (17%)
Query: 365 FGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPS 424
F R E + + P+ V R P G+S L P+P +V L+ P +
Sbjct: 186 FSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSH 245
Query: 425 L----------GIGVSGPEVKV------PKGPEVK--LPKAPEVKLPKV----PEAALPE 462
L + + PE V P G V P+ P+ ++ + PE +P+
Sbjct: 246 LRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPD 305
Query: 463 VRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAV-------PEV 515
+ L E +VS ++ P+ E V + PE VS + P+ PE V PE
Sbjct: 306 LCL-EPPKSRVSHLR-PEPSETGVSHLH-PEPPKTLVSSLH-PEPPETGVSHLCPEPPET 361
Query: 516 RLPEVQLLK----VSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRL-- 569
R+ ++ L VS + P+ P+ VP +R PE VS + PE + + +R
Sbjct: 362 RVSPLRQLPPEAGVSHL-CPEPPKTRVPPLR-PETPKNGVSPL-FPEPPKTRISNLRSEP 418
Query: 570 PEVQLPKV----PEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHL--PEVQL 623
P++ + + P+ + ++ P+ PE + ++ P+ P+ V +HL PE +
Sbjct: 419 PKIGVSHLCLEPPKTRGSHLR-PEPPETGVSHLR------PEPPKTRVSSLHLEPPETGV 471
Query: 624 ----PKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVR 679
P+ PE + ++ P+ P+ V + PE +V ++ P+ E V +R
Sbjct: 472 SHLCPEPPEKDVSHLR------PEPPDTGVSHL-CPEPPKTRVSHLR-PEPSETGVSHLR 523
Query: 680 LPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKL-PKVPEMAVP 738
PE PK+ L + P + PE V ++ K L P+ P+ V
Sbjct: 524 -PEP--PKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVS 580
Query: 739 DVHLPEVQLPKVSEIRLPEMQVPKVPDVHL-PKAPEVKL----PRAPEVQLKATKAEQAE 793
+ PE +VS + + P+ HL P+ PE ++ P PE + + E
Sbjct: 581 HL-CPEPPKTRVSSL---PPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEP-- 634
Query: 794 GMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHV 847
PK M L R E P+ G ++ +LP PE G +H+
Sbjct: 635 --------PKTRMYSL-RPEPPNTGVSHLCPEPPKTRVSSLPPEPPET-GVSHL 678
Score = 41.2 bits (95), Expect = 0.007
Identities = 58/247 (23%), Positives = 91/247 (36%), Gaps = 28/247 (11%)
Query: 278 PAPPAVEAPAVGIQVPQVELPALPSLP--TLPTLPCLETREGAVSVVVPTLDVAAPTVGV 335
P PP + + P+ + +LP P T + C E E VS + P P GV
Sbjct: 572 PEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPE----PPETGV 627
Query: 336 DLALPGAE----VEARGEAPEVAL-----KMPRLSFPRFGARAKEVAEAKVAKVSPEARV 386
P R E P + + P+ E + + PE RV
Sbjct: 628 SHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRV 687
Query: 387 KGPRLRMPTFGLSLLEPRPAAPEV-------VESKLKLPTIKMPSLGIGVSGPEVKVPKG 439
R P G+S L P P V ES++ + P G+ PE P+
Sbjct: 688 SHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRV 747
Query: 440 PEVKLPKAPEVKL----PKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVE 495
++ P+ E ++ P+ PE + + PE+ P+VS + L V +RL +
Sbjct: 748 SSLR-PEPLETRVSHLRPEPPETGVSHLH-PELPKPRVSSLHLEPPKTRRVSSLRLEPPK 805
Query: 496 LPKVSEM 502
+VS +
Sbjct: 806 TGRVSSL 812
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 64.3 bits (155), Expect = 8e-10
Identities = 149/619 (24%), Positives = 202/619 (32%), Gaps = 115/619 (18%)
Query: 212 PPPRKAKVEAEVAAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGF---AL 268
PP A + AAGA P E G + GA + P+ SAP+A P+ A A
Sbjct: 37 PPVTPAALRVLGAAGAVGRKPLAERAGG-IGGATI--PE-SAPRAGPTRSAGTSSRNPAS 92
Query: 269 HLPTLGLGAPAPPA-------VEAPA-------------VGIQVPQVELPALPSLPTLPT 308
P G G APPA V +P G+++ E A P
Sbjct: 93 RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 152
Query: 309 LPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRLSF----PR 364
L GA D + PT G P +R EV L P S P
Sbjct: 153 RSALSA--GA------RRDTSGPTPGTPS--PAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 365 FGAR--AKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKM 422
G R +E + SP AR R P+ G L P + + L P
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAAR------RRPSAGGGLQRPASRSLSSSATPLSSPARSG 256
Query: 423 PSL-GIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEA-----------ALPEVRLPEVEL 470
PS G + PK ++ + P+V P+ A A P P L
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS---PSAAL 313
Query: 471 PKVSEMKLPKVP-------EMAVPEVRLPEVELPKVSEMKLPKVP---------EMAVPE 514
+ LP P ++A P P S LP P + P
Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373
Query: 515 VRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPE--- 571
++ L L P A P + LP +Q P S P +S +A P + P
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP-SPPASPPLSPLATPSPQAPNALA 432
Query: 572 ---------------VQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDV 616
VQ P P P P P + P +Q+P P A P +
Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPM 491
Query: 617 HLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQ-LPKVPEM---KLPKMPE 672
P+ P P + P ++L K P A P + P +Q LP P + P P
Sbjct: 492 SPSATPPPQAP----PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 547
Query: 673 MAVP--EVRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKL--PEIK 728
++P + P Q P V L +VP P +Q P+ PD + P +
Sbjct: 548 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS---PTLQAPRRPPTPGPDTSVSGPRLT 604
Query: 729 LPKVPEMAVPDVHLPEVQL 747
L P P P L
Sbjct: 605 LALAPGPPPPPSRSPSSTL 623
Score = 37.7 bits (86), Expect = 0.082
Identities = 113/505 (22%), Positives = 172/505 (34%), Gaps = 86/505 (17%)
Query: 725 PEIKLPKVPEMAVPDVHLPEVQLPK-------VSEIRLPEMQVPKVPDVHL-------PK 770
P L P A P + LP +Q P +S + P Q P VHL P
Sbjct: 385 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444
Query: 771 APEVKL----PRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAE 826
+P V+ P +P V AT QA + P SPS P +A
Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
Query: 827 VSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPG--ALGLQGQVPAAKMGKGERVEG 884
++ + L P+ A P LPS PG +P + +
Sbjct: 505 LAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 563
Query: 885 PEVAAGVREVGFRVP-SVEIVTPQLPA-----VEIEEGRLEMIETKVKPSSKFSLPKFGL 938
P +AA + +V P S + P+ P + RL + P P L
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 623
Query: 939 SGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSL 998
SGP +A S A S P+ G ++ +G A P +L+ +
Sbjct: 624 SGPDLAGH-------------SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 670
Query: 999 DAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKM 1058
+ P+ + GA P LP G +A+ + + E EG
Sbjct: 671 WSRGPAPPLAFRGA------PGAPLPWPPATG--PGSADGLCTIYETEG----------- 711
Query: 1059 PKLKMPSFG-LARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEE-------- 1109
P+ P+ G L G G +A+ G A +++ K + + LGA +
Sbjct: 712 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLS 771
Query: 1110 -----GRAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAG 1164
AEGA SG G + G VT G A +L EL + E
Sbjct: 772 RTLLLAAAEGAAGGSGGGPGGAE----GGGVTGGARA---------ALSDAELGRWAELL 818
Query: 1165 TPGQQAQSTVPSAEGTAGYRVQVPQ 1189
+P ++++++ S + V PQ
Sbjct: 819 SPLDESRASITSVTSFSPDDVASPQ 843
Score = 32.0 bits (71), Expect = 4.5
Identities = 49/200 (24%), Positives = 64/200 (32%), Gaps = 34/200 (17%)
Query: 1255 RVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLP----- 1309
R GG G P A R P S N A A G GE K P
Sbjct: 61 RAGGIGGATIPESAPRAG----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
Query: 1310 --------------RFGL-VRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEE 1354
+ GL + A+E G+ ++PK G + G+PSP
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 1355 EEEEEEEGSGEG----ASGRRGRVRVRLPRVGLAAPSKASRGQEGDAAPKSP------VR 1404
G+ G A R R PR +++ S+ S + AA + P R
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 1405 EKSPKFRFPRVSLSPKARSG 1424
S LS ARSG
Sbjct: 237 PASRSLSSSATPLSSPARSG 256
>gi|239753930 PREDICTED: hypothetical protein [Homo sapiens]
Length = 196
Score = 59.3 bits (142), Expect = 3e-08
Identities = 53/165 (32%), Positives = 83/165 (50%), Gaps = 17/165 (10%)
Query: 541 VRLPEV--QLPKVSEMKLPEVSEVAV-PEVRLPEVQLPKVPEMKVPEMKLPKV--PEMKL 595
V LPEV LP +S + EV+ +V + +P + P VP+ L + PE L
Sbjct: 36 VVLPEVTFSLPVLSSLSPLEVTSFSVWYSLLVPGLTFPDTSS-NVPQSGLLGLAFPEPGL 94
Query: 596 PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLP 655
+KLP+ + P +PD L EVQ P LP +LP ++P +P + +P P
Sbjct: 95 SGLKLPDSEC-HCP--VLPDTELSEVQCPA-----LPRSELPGFQVPVLPGLGLPGFWFP 146
Query: 656 EVQLPKVPEMKLPKMPEMAVP--EVRLPEV-QLPKVSEMKLPKVP 697
+ +P++PE +LP +P +P +V +P V +LP V +VP
Sbjct: 147 VLPVPELPEFQLPALPGPELPGFQVAVPPVPELPGVPASSTARVP 191
Score = 57.8 bits (138), Expect = 8e-08
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 49/194 (25%)
Query: 489 VRLPEV--ELPKVSEMKLPKVPEMAV------PEVRLPEVQLLKVSEMKLPKVPEMAVPE 540
V LPEV LP +S + +V +V P + P+ VP+ +
Sbjct: 36 VVLPEVTFSLPVLSSLSPLEVTSFSVWYSLLVPGLTFPDTS---------SNVPQSGLLG 86
Query: 541 VRLPEVQLPKVSEMKLPEVSEV---AVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPE 597
+ PE P +S +KLP+ SE +P+ L EVQ P +P ++P ++P +P + LP
Sbjct: 87 LAFPE---PGLSGLKLPD-SECHCPVLPDTELSEVQCPALPRSELPGFQVPVLPGLGLPG 142
Query: 598 MKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEV 657
P + +P+ LPE QLP +P +LP +V +P VPE
Sbjct: 143 FWFPVLPVPE----------LPEFQLPALPGPELPGF---QVAVPPVPE----------- 178
Query: 658 QLPKVPEMKLPKMP 671
LP VP ++P
Sbjct: 179 -LPGVPASSTARVP 191
Score = 56.2 bits (134), Expect = 2e-07
Identities = 54/192 (28%), Positives = 89/192 (46%), Gaps = 24/192 (12%)
Query: 442 VKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSE 501
V L +P + V L R V LP+V+ LP + ++ +E+ S
Sbjct: 10 VSLTNSPNIGPITVLVTVLEHERRVVVVLPEVT-FSLPVLSSLS-------PLEVTSFSV 61
Query: 502 MKLPKVPEMAVPEV--RLPEVQLLKVSEMKLPKVPEMAVPEVRLP--EVQLPKVSEMKLP 557
VP + P+ +P+ LL ++ PE + ++LP E P + + +L
Sbjct: 62 WYSLLVPGLTFPDTSSNVPQSGLLGLA------FPEPGLSGLKLPDSECHCPVLPDTELS 115
Query: 558 EVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVP--EMAVPD 615
EV A+P LP Q+P +P + +P P +P +LPE +LP + P++P ++AVP
Sbjct: 116 EVQCPALPRSELPGFQVPVLPGLGLPGFWFPVLPVPELPEFQLPALPGPELPGFQVAVP- 174
Query: 616 VHLPEVQLPKVP 627
P +LP VP
Sbjct: 175 ---PVPELPGVP 183
Score = 52.8 bits (125), Expect = 2e-06
Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 15/134 (11%)
Query: 647 MAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHL 706
+ VP + P+ VP+ L + A PE L ++LP SE P +PD L
Sbjct: 65 LLVPGLTFPDTS-SNVPQSGLLGL---AFPEPGLSGLKLPD-SECHCP-----VLPDTEL 114
Query: 707 PEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDV 766
EVQ P + P +LP ++P +P + +P P + +P++ E +LP + P++P
Sbjct: 115 SEVQCPAL-----PRSELPGFQVPVLPGLGLPGFWFPVLPVPELPEFQLPALPGPELPGF 169
Query: 767 HLPKAPEVKLPRAP 780
+ P +LP P
Sbjct: 170 QVAVPPVPELPGVP 183
Score = 43.1 bits (100), Expect = 0.002
Identities = 47/162 (29%), Positives = 66/162 (40%), Gaps = 25/162 (15%)
Query: 374 EAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLG------- 426
E +V V PE P L S L P V L +P + P
Sbjct: 31 ERRVVVVLPEVTFSLPVL-------SSLSPLEVTSFSVWYSLLVPGLTFPDTSSNVPQSG 83
Query: 427 -IGVSGPE-----VKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPK 480
+G++ PE +K+P E P P+ +L +V ALP LP ++P + + LP
Sbjct: 84 LLGLAFPEPGLSGLKLPDS-ECHCPVLPDTELSEVQCPALPRSELPGFQVPVLPGLGLPG 142
Query: 481 V--PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEV 520
P + VPE LPE +LP + +LP P LP V
Sbjct: 143 FWFPVLPVPE--LPEFQLPALPGPELPGFQVAVPPVPELPGV 182
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 59.3 bits (142), Expect = 3e-08
Identities = 107/419 (25%), Positives = 139/419 (33%), Gaps = 54/419 (12%)
Query: 179 VPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVG 238
VP P+ Q P L+ E+ A PPP AG L
Sbjct: 888 VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLP-----GAGI--------LPL 934
Query: 239 PRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELP 298
P LPGA + P A P G + LP GA PP P GI P P
Sbjct: 935 PPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPP----P 990
Query: 299 ALP--SLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVALK 356
LP +P P LP GA P L A + LPGA + P +
Sbjct: 991 PLPGAGIPPPPPLP------GAGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIP 1042
Query: 357 MPRLSFPRFGARAKEVAEAKVAKVSPEARVKG----PRLRMPTFGLSLLEPRPAAPEVVE 412
P P GA A + P + G P +P G+ P P A
Sbjct: 1043 PPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-- 1097
Query: 413 SKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPK 472
P +P +GI P P LP A P +P A +P P LP+
Sbjct: 1098 -----PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP----PPPPLPR 1148
Query: 473 VSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPK 532
V P +P +P P LP P +P + +P P L V P
Sbjct: 1149 VGIPPPPPLPGAGIP----PPPPLPGAGIPPPPPLPGVGIP----PPPPLPGVGIPPPPP 1200
Query: 533 VPEMAV-PEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKV 590
+P + P LP + +P LP P LP P +P++ + P+V
Sbjct: 1201 LPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259
Score = 34.3 bits (77), Expect = 0.90
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Query: 182 APARRRLQLPRLRVREVAEEAQAAR--LAAAAPPPRKAKVEAEVAAGARFTAPQVELVGP 239
+P++ Q PR++ R ++ +R LA+ A P +K + + +AAG +A E +G
Sbjct: 432 SPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGA 491
Query: 240 RLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPA 279
R P VG + ++++ GG + L GAPA
Sbjct: 492 RTP--RVG-GSAHLLERGVASDSGGGVSPALAAKASGAPA 528
>gi|239748472 PREDICTED: hypothetical protein [Homo sapiens]
Length = 196
Score = 58.9 bits (141), Expect = 3e-08
Identities = 53/165 (32%), Positives = 83/165 (50%), Gaps = 17/165 (10%)
Query: 541 VRLPEV--QLPKVSEMKLPEVSEVAV-PEVRLPEVQLPKVPEMKVPEMKLPKV--PEMKL 595
V LPEV LP +S + EV+ +V + +P + P VP+ L + PE L
Sbjct: 36 VVLPEVTFSLPVLSSLSPLEVTSFSVWYSLLVPGLTFPDTSS-NVPQSGLLGLAFPEPGL 94
Query: 596 PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLP 655
+KLP+ + P +PD L EVQ P LP +LP ++P +P + +P P
Sbjct: 95 SGLKLPDSEC-HCP--VLPDTELSEVQCPA-----LPRSELPGFQVPVLPGLGLPGFWFP 146
Query: 656 EVQLPKVPEMKLPKMPEMAVP--EVRLPEV-QLPKVSEMKLPKVP 697
+ +P++PE +LP +P +P +V +P V +LP V +VP
Sbjct: 147 VLPVPELPEFQLPVLPGPELPGFQVAVPPVPELPGVPASSTARVP 191
Score = 57.4 bits (137), Expect = 1e-07
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 49/194 (25%)
Query: 489 VRLPEV--ELPKVSEMKLPKVPEMAV------PEVRLPEVQLLKVSEMKLPKVPEMAVPE 540
V LPEV LP +S + +V +V P + P+ VP+ +
Sbjct: 36 VVLPEVTFSLPVLSSLSPLEVTSFSVWYSLLVPGLTFPDTS---------SNVPQSGLLG 86
Query: 541 VRLPEVQLPKVSEMKLPEVSEV---AVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPE 597
+ PE P +S +KLP+ SE +P+ L EVQ P +P ++P ++P +P + LP
Sbjct: 87 LAFPE---PGLSGLKLPD-SECHCPVLPDTELSEVQCPALPRSELPGFQVPVLPGLGLPG 142
Query: 598 MKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEV 657
P + +P+ LPE QLP +P +LP +V +P VPE
Sbjct: 143 FWFPVLPVPE----------LPEFQLPVLPGPELPGF---QVAVPPVPE----------- 178
Query: 658 QLPKVPEMKLPKMP 671
LP VP ++P
Sbjct: 179 -LPGVPASSTARVP 191
Score = 55.8 bits (133), Expect = 3e-07
Identities = 54/192 (28%), Positives = 89/192 (46%), Gaps = 24/192 (12%)
Query: 442 VKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSE 501
V L +P + V L R V LP+V+ LP + ++ +E+ S
Sbjct: 10 VSLTNSPNIGPITVLVTVLEHERRVVVVLPEVT-FSLPVLSSLS-------PLEVTSFSV 61
Query: 502 MKLPKVPEMAVPEV--RLPEVQLLKVSEMKLPKVPEMAVPEVRLP--EVQLPKVSEMKLP 557
VP + P+ +P+ LL ++ PE + ++LP E P + + +L
Sbjct: 62 WYSLLVPGLTFPDTSSNVPQSGLLGLA------FPEPGLSGLKLPDSECHCPVLPDTELS 115
Query: 558 EVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVP--EMAVPD 615
EV A+P LP Q+P +P + +P P +P +LPE +LP + P++P ++AVP
Sbjct: 116 EVQCPALPRSELPGFQVPVLPGLGLPGFWFPVLPVPELPEFQLPVLPGPELPGFQVAVP- 174
Query: 616 VHLPEVQLPKVP 627
P +LP VP
Sbjct: 175 ---PVPELPGVP 183
Score = 52.4 bits (124), Expect = 3e-06
Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 15/134 (11%)
Query: 647 MAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHL 706
+ VP + P+ VP+ L + A PE L ++LP SE P +PD L
Sbjct: 65 LLVPGLTFPDTS-SNVPQSGLLGL---AFPEPGLSGLKLPD-SECHCP-----VLPDTEL 114
Query: 707 PEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDV 766
EVQ P + P +LP ++P +P + +P P + +P++ E +LP + P++P
Sbjct: 115 SEVQCPAL-----PRSELPGFQVPVLPGLGLPGFWFPVLPVPELPEFQLPVLPGPELPGF 169
Query: 767 HLPKAPEVKLPRAP 780
+ P +LP P
Sbjct: 170 QVAVPPVPELPGVP 183
Score = 42.7 bits (99), Expect = 0.003
Identities = 47/162 (29%), Positives = 66/162 (40%), Gaps = 25/162 (15%)
Query: 374 EAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLG------- 426
E +V V PE P L S L P V L +P + P
Sbjct: 31 ERRVVVVLPEVTFSLPVL-------SSLSPLEVTSFSVWYSLLVPGLTFPDTSSNVPQSG 83
Query: 427 -IGVSGPE-----VKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPK 480
+G++ PE +K+P E P P+ +L +V ALP LP ++P + + LP
Sbjct: 84 LLGLAFPEPGLSGLKLPDS-ECHCPVLPDTELSEVQCPALPRSELPGFQVPVLPGLGLPG 142
Query: 481 V--PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEV 520
P + VPE LPE +LP + +LP P LP V
Sbjct: 143 FWFPVLPVPE--LPEFQLPVLPGPELPGFQVAVPPVPELPGV 182
>gi|239742436 PREDICTED: hypothetical protein [Homo sapiens]
Length = 196
Score = 58.9 bits (141), Expect = 3e-08
Identities = 53/165 (32%), Positives = 83/165 (50%), Gaps = 17/165 (10%)
Query: 541 VRLPEV--QLPKVSEMKLPEVSEVAV-PEVRLPEVQLPKVPEMKVPEMKLPKV--PEMKL 595
V LPEV LP +S + EV+ +V + +P + P VP+ L + PE L
Sbjct: 36 VVLPEVTFSLPVLSSLSPLEVTSFSVWYSLLVPGLTFPDTSS-NVPQSGLLGLAFPEPGL 94
Query: 596 PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLP 655
+KLP+ + P +PD L EVQ P LP +LP ++P +P + +P P
Sbjct: 95 SGLKLPDSEC-HCP--VLPDTELSEVQCPA-----LPRSELPGFQVPVLPGLGLPGFWFP 146
Query: 656 EVQLPKVPEMKLPKMPEMAVP--EVRLPEV-QLPKVSEMKLPKVP 697
+ +P++PE +LP +P +P +V +P V +LP V +VP
Sbjct: 147 VLPVPELPEFQLPVLPGPELPGFQVAVPPVPELPGVPASSTARVP 191
Score = 57.4 bits (137), Expect = 1e-07
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 49/194 (25%)
Query: 489 VRLPEV--ELPKVSEMKLPKVPEMAV------PEVRLPEVQLLKVSEMKLPKVPEMAVPE 540
V LPEV LP +S + +V +V P + P+ VP+ +
Sbjct: 36 VVLPEVTFSLPVLSSLSPLEVTSFSVWYSLLVPGLTFPDTS---------SNVPQSGLLG 86
Query: 541 VRLPEVQLPKVSEMKLPEVSEV---AVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPE 597
+ PE P +S +KLP+ SE +P+ L EVQ P +P ++P ++P +P + LP
Sbjct: 87 LAFPE---PGLSGLKLPD-SECHCPVLPDTELSEVQCPALPRSELPGFQVPVLPGLGLPG 142
Query: 598 MKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEV 657
P + +P+ LPE QLP +P +LP +V +P VPE
Sbjct: 143 FWFPVLPVPE----------LPEFQLPVLPGPELPGF---QVAVPPVPE----------- 178
Query: 658 QLPKVPEMKLPKMP 671
LP VP ++P
Sbjct: 179 -LPGVPASSTARVP 191
Score = 55.8 bits (133), Expect = 3e-07
Identities = 54/192 (28%), Positives = 89/192 (46%), Gaps = 24/192 (12%)
Query: 442 VKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSE 501
V L +P + V L R V LP+V+ LP + ++ +E+ S
Sbjct: 10 VSLTNSPNIGPITVLVTVLEHERRVVVVLPEVT-FSLPVLSSLS-------PLEVTSFSV 61
Query: 502 MKLPKVPEMAVPEV--RLPEVQLLKVSEMKLPKVPEMAVPEVRLP--EVQLPKVSEMKLP 557
VP + P+ +P+ LL ++ PE + ++LP E P + + +L
Sbjct: 62 WYSLLVPGLTFPDTSSNVPQSGLLGLA------FPEPGLSGLKLPDSECHCPVLPDTELS 115
Query: 558 EVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVP--EMAVPD 615
EV A+P LP Q+P +P + +P P +P +LPE +LP + P++P ++AVP
Sbjct: 116 EVQCPALPRSELPGFQVPVLPGLGLPGFWFPVLPVPELPEFQLPVLPGPELPGFQVAVP- 174
Query: 616 VHLPEVQLPKVP 627
P +LP VP
Sbjct: 175 ---PVPELPGVP 183
Score = 52.4 bits (124), Expect = 3e-06
Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 15/134 (11%)
Query: 647 MAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVPDVHL 706
+ VP + P+ VP+ L + A PE L ++LP SE P +PD L
Sbjct: 65 LLVPGLTFPDTS-SNVPQSGLLGL---AFPEPGLSGLKLPD-SECHCP-----VLPDTEL 114
Query: 707 PEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDV 766
EVQ P + P +LP ++P +P + +P P + +P++ E +LP + P++P
Sbjct: 115 SEVQCPAL-----PRSELPGFQVPVLPGLGLPGFWFPVLPVPELPEFQLPVLPGPELPGF 169
Query: 767 HLPKAPEVKLPRAP 780
+ P +LP P
Sbjct: 170 QVAVPPVPELPGVP 183
Score = 42.7 bits (99), Expect = 0.003
Identities = 47/162 (29%), Positives = 66/162 (40%), Gaps = 25/162 (15%)
Query: 374 EAKVAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLG------- 426
E +V V PE P L S L P V L +P + P
Sbjct: 31 ERRVVVVLPEVTFSLPVL-------SSLSPLEVTSFSVWYSLLVPGLTFPDTSSNVPQSG 83
Query: 427 -IGVSGPE-----VKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPK 480
+G++ PE +K+P E P P+ +L +V ALP LP ++P + + LP
Sbjct: 84 LLGLAFPEPGLSGLKLPDS-ECHCPVLPDTELSEVQCPALPRSELPGFQVPVLPGLGLPG 142
Query: 481 V--PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEV 520
P + VPE LPE +LP + +LP P LP V
Sbjct: 143 FWFPVLPVPE--LPEFQLPVLPGPELPGFQVAVPPVPELPGV 182
>gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens]
Length = 1180
Score = 58.5 bits (140), Expect = 4e-08
Identities = 69/227 (30%), Positives = 98/227 (43%), Gaps = 22/227 (9%)
Query: 561 EVAVPEVRLPEVQLPKVPEMKV---PEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVH 617
EV++ R PE + PE V PE + PE + PE + PE AV H
Sbjct: 37 EVSLYRRRAPEAAVFHSPEAAVYHSPEATVYHSPEAAVYHS--PEAAVFHSPEAAV--YH 92
Query: 618 LPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPE 677
PE + PE + PE + PE AV H PE + PE + + PE AV
Sbjct: 93 SPEAAVYHSPEAAV--FHSPEAAVYHSPEAAV--FHSPEAAVFHSPEAAVYRSPEAAV-- 146
Query: 678 VRLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAV 737
R PE + + E + + PE AV PE + + E V + PE + + PE AV
Sbjct: 147 FRSPEAAVYRSPEAAVFRSPEAAV--YRSPEAAVFRSPEAAV--YRSPEAAVYRSPEAAV 202
Query: 738 PDVHLPEVQL---PKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPE 781
H PE + P+ + R PE V + P+ + PE + +PE
Sbjct: 203 --FHSPEAAVFHCPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPE 247
Score = 55.5 bits (132), Expect = 4e-07
Identities = 67/244 (27%), Positives = 99/244 (40%), Gaps = 23/244 (9%)
Query: 432 PEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRL 491
PE V PE + +PE + PEAA+ PE + E + PE AV
Sbjct: 46 PEAAVFHSPEAAVYHSPEATVYHSPEAAV--YHSPEAAVFHSPEAAVYHSPEAAV--YHS 101
Query: 492 PEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKV 551
PE + E + PE AV PE + E + + PE AV + P+
Sbjct: 102 PEAAVFHSPEAAVYHSPEAAV--FHSPEAAVFHSPEAAVYRSPEAAV-------FRSPEA 152
Query: 552 SEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEM 611
+ + PE + PE + + P+ + PE + + PE + + PE + PE
Sbjct: 153 AVYRSPEAAVFRSPEAAV--YRSPEAAVFRSPEAAVYRSPEAAV--YRSPEAAVFHSPEA 208
Query: 612 AVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMP 671
AV H PE + + PE + + PE + PE AV H PE + PE + P
Sbjct: 209 AV--FHCPEAAVYRSPEAAV--YRSPEAAVFHCPEAAV--YHSPEAAVYHSPEASVFHSP 262
Query: 672 EMAV 675
AV
Sbjct: 263 GAAV 266
>gi|105990532 apolipoprotein B precursor [Homo sapiens]
Length = 4563
Score = 56.6 bits (135), Expect = 2e-07
Identities = 51/177 (28%), Positives = 88/177 (49%), Gaps = 31/177 (17%)
Query: 590 VPEMK--LPEMKLPEVQLPKVPEMA--VPDVHLPEVQLPKVPEMKLPEMKLPEVKLPK-- 643
VPE+K L M EV L + + PD +P L ++P +++ L +K+P
Sbjct: 2587 VPEIKTILGTMPAFEVSLQALQKATFQTPDFIVPLTDL-RIPSVQINFKDLKNIKIPSRF 2645
Query: 644 -VPEMAVPDV-HLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAV 701
PE + + H+P + V EM V +R + L SE++ P VP++ +
Sbjct: 2646 STPEFTILNTFHIPSFTIDFV---------EMKVKIIRTIDQMLN--SELQWP-VPDIYL 2693
Query: 702 PDVHLPEVQLPKVCEMKVPDMKLPEIKLPK-------VPEMAVPDVHLPEVQLPKVS 751
D+ + ++ L ++ +PD +LPEI +P+ + + VPD+H+PE QLP +S
Sbjct: 2694 RDLKVEDIPLARIT---LPDFRLPEIAIPEFIIPTLNLNDFQVPDLHIPEFQLPHIS 2747
Score = 47.4 bits (111), Expect = 1e-04
Identities = 42/184 (22%), Positives = 89/184 (48%), Gaps = 29/184 (15%)
Query: 428 GVSGPEVKVPKGP----EVKLPKAPEVKLPKVPEAALP--EVRLPEVELPKVSEMKLPKV 481
G + PE+K G EV L + + P+ +P ++R+P V++ ++K K+
Sbjct: 2584 GFTVPEIKTILGTMPAFEVSLQALQKATF-QTPDFIVPLTDLRIPSVQI-NFKDLKNIKI 2641
Query: 482 PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEV 541
P P+ + + +P + V + +V++++ + L + VP++
Sbjct: 2642 PS---------RFSTPEFTILNTFHIPSFTIDFVEM-KVKIIRTIDQMLNSELQWPVPDI 2691
Query: 542 RLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLP--KVPEMKLPEMK 599
L ++ KV ++ L + + +P+ RLPE+ +PE +P + L +VP++ +PE +
Sbjct: 2692 YLRDL---KVEDIPL---ARITLPDFRLPEIA---IPEFIIPTLNLNDFQVPDLHIPEFQ 2742
Query: 600 LPEV 603
LP +
Sbjct: 2743 LPHI 2746
Score = 46.2 bits (108), Expect = 2e-04
Identities = 43/199 (21%), Positives = 98/199 (49%), Gaps = 23/199 (11%)
Query: 410 VVESKLKLPTIK-----MPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPE--AALPE 462
+VE +P IK MP+ + + + + P+ +P ++++P V L
Sbjct: 2580 LVEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPDFIVPLT-DLRIPSVQINFKDLKN 2638
Query: 463 VRLPE-VELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQ 521
+++P P+ + + +P + V + +V++ + + L + VP++ L +
Sbjct: 2639 IKIPSRFSTPEFTILNTFHIPSFTIDFVEM-KVKIIRTIDQMLNSELQWPVPDIYLRD-- 2695
Query: 522 LLKVSEMKLPKV--PEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPE 579
LKV ++ L ++ P+ +PE+ +PE +P ++ +++ VP++ +PE QLP +
Sbjct: 2696 -LKVEDIPLARITLPDFRLPEIAIPEFIIPTLN------LNDFQVPDLHIPEFQLPHISH 2748
Query: 580 -MKVPEM-KLPKVPEMKLP 596
++VP KL + +++ P
Sbjct: 2749 TIEVPTFGKLYSILKIQSP 2767
Score = 44.3 bits (103), Expect = 9e-04
Identities = 37/165 (22%), Positives = 79/165 (47%), Gaps = 19/165 (11%)
Query: 393 MPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSG-PEVKVPKGPEVKLPKAPEVK 451
MP F +SL + A + + + L +++PS+ I +K+P P+ +
Sbjct: 2597 MPAFEVSLQALQKATFQTPDFIVPLTDLRIPSVQINFKDLKNIKIPS--RFSTPEFTILN 2654
Query: 452 LPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKV--SEMKLP--KV 507
+P + V + +V++ + + L + VP++ L ++++ + + + LP ++
Sbjct: 2655 TFHIPSFTIDFVEM-KVKIIRTIDQMLNSELQWPVPDIYLRDLKVEDIPLARITLPDFRL 2713
Query: 508 PEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVS 552
PE+A+PE +P + L + VP++ +PE QLP +S
Sbjct: 2714 PEIAIPEFIIPTLNL-----------NDFQVPDLHIPEFQLPHIS 2747
Score = 37.0 bits (84), Expect = 0.14
Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 12/149 (8%)
Query: 538 VPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLP--EVQLPKVPEMKVPEMKLPKVPEMKL 595
+P ++L ++ V +++ VP +L E+Q+ K + LP +PE+K
Sbjct: 3732 IPGLKLNDLNSVLVMPTFHVPFTDLQVPSCKLDFREIQIYKKLRTSSFALNLPTLPEVKF 3791
Query: 596 PEMKL------PEVQLPKVPEMAVPDVHLPEVQ--LPKVPEMKLPEMKLPEVKLPKVPEM 647
PE+ + PE L E+ VP+ L Q LPK + + L V K+ +
Sbjct: 3792 PEVDVLTKYSQPEDSLIPFFEITVPESQLTVSQFTLPKSVSDGIAALDLNAV-ANKIADF 3850
Query: 648 AVPDVHLPEVQLPKVPEMKLPKMPEMAVP 676
+P + +PE Q ++P +K + +P
Sbjct: 3851 ELPTIIVPE-QTIEIPSIKFSVPAGIVIP 3878
Score = 32.0 bits (71), Expect = 4.5
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 18/103 (17%)
Query: 442 VKLPKAPEVKLPKV--------PEAALP---EVRLPEVELPKVSEMKLPKVPEMAVPEVR 490
+ LP PEVK P+V PE +L E+ +PE +L VS+ LPK + +
Sbjct: 3781 LNLPTLPEVKFPEVDVLTKYSQPEDSLIPFFEITVPESQL-TVSQFTLPKSVSDGIAALD 3839
Query: 491 LPEVELPKVSEMKLPKVPEMAVPE--VRLPEVQLLKVSEMKLP 531
L V K+++ +LP + VPE + +P ++ + + +P
Sbjct: 3840 LNAV-ANKIADFELPTI---IVPEQTIEIPSIKFSVPAGIVIP 3878
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 56.6 bits (135), Expect = 2e-07
Identities = 106/470 (22%), Positives = 163/470 (34%), Gaps = 43/470 (9%)
Query: 213 PPRKAKVEAEVAAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPT 272
PP + + A V A TAP + P ++ + + P+ E G A
Sbjct: 1337 PPFLSSI-AGVPTTAAATAP---VPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGV 1392
Query: 273 LGLGA-PAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVV-PTLDVAA 330
+ G P PP E+P + V + +PA+ S+ T T P L+ +VV T +
Sbjct: 1393 VTSGGLPIPPVSESPVLSSVVSSITIPAVVSIST--TSPSLQVPTSTSEIVVSSTALYPS 1450
Query: 331 PTVGVDLALPGAEVEARGEAPEVALKMPRLSFPRFGARAKEV-------AEAKVAKVSPE 383
TV A G G P + GA V + A +
Sbjct: 1451 VTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLS 1510
Query: 384 ARVKGPRL--RMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKVPKGPE 441
+ P L + SL + ++ + L P+ S G GVS + P G
Sbjct: 1511 SSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPS-SSSSPGAGVSS-YISQPGGLH 1568
Query: 442 VKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSE 501
+ + P +P+AA P S LP+VP ++P + P +P V +
Sbjct: 1569 PLVIPSVIASTPILPQAAGP-----------TSTPLLPQVP--SIPPLVQPVANVPAVQQ 1615
Query: 502 MKLPKVPEMAV----PEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLP 557
+ P+ A+ P PEV ++ K P + ++ E +L + + S
Sbjct: 1616 TLIHSQPQPALLPNQPHTHCPEVD--SDTQPKAPGIDDIKTLEEKLRSL-FSEHSSSGAQ 1672
Query: 558 EVSEVAVPEVRLPEVQLPKVPEMKV-PEMKLPKVPEMKLPEMKLP--EVQLPKVPEMAVP 614
S + + P +P V P L LP LP V LP P +
Sbjct: 1673 HASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPG 1732
Query: 615 DVHLPEVQLPKVPEMKLPEMKLPEVKLPKVP-EMAVPDVHLPEVQLPKVP 663
V P + K P K P +P +P LP QLP P
Sbjct: 1733 QVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFP 1782
Score = 34.3 bits (77), Expect = 0.90
Identities = 46/196 (23%), Positives = 80/196 (40%), Gaps = 20/196 (10%)
Query: 724 LPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQ 783
LP++ P +P + P ++P VQ + P + +P P H P+ P+AP +
Sbjct: 1594 LPQV--PSIPPLVQPVANVPAVQQTLIHSQPQPAL-LPNQPHTHCPEVDSDTQPKAPGID 1650
Query: 784 LKATKAEQ-----AEGMEFGFKMPKMTMPKLGRAESP-SRGKPGEAGAEVSGKLV---TL 834
T E+ +E G + +++ ES + G P A A KL+ T
Sbjct: 1651 DIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVA--PSKLLTSTTS 1708
Query: 835 PCLQPEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVA-AGVRE 893
CL P ++ + ++ LP + PG + + + G P + A V
Sbjct: 1709 TCLPP-----TNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLP 1763
Query: 894 VGFRVPSVEIVTPQLP 909
VG +P+ + + QLP
Sbjct: 1764 VGTELPAGTLPSEQLP 1779
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 55.8 bits (133), Expect = 3e-07
Identities = 67/215 (31%), Positives = 99/215 (46%), Gaps = 20/215 (9%)
Query: 424 SLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPE 483
+L + V G E KV K + P+ E + K PE P+VE K+ ++K P VPE
Sbjct: 4615 TLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE 4674
Query: 484 MAVPEVRLPEVELPKVS--EMKLP---KVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAV 538
P+ + EVE+P V+ E K+P KVPE+ P + LP + PK PE V
Sbjct: 4675 PPPPK-PVEEVEVPTVTKRERKIPEPTKVPEIK-PAIPLPAPE-------PKPK-PEAEV 4724
Query: 539 PEVRLPEVQ---LPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKL 595
++ P V+ P + + +P V + A + E PK P VP+ K P E +
Sbjct: 4725 KTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAER 4783
Query: 596 PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMK 630
+++ P K P+ A L V L V E+K
Sbjct: 4784 RKLR-PGSGGEKPPDEAPFTYQLKAVPLKFVKEIK 4817
Score = 50.4 bits (119), Expect = 1e-05
Identities = 49/162 (30%), Positives = 73/162 (45%), Gaps = 17/162 (10%)
Query: 545 EVQLPKVSEMKLPEVSEVAVPEVRL---PEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLP 601
E ++ K+ + PE E V + L PE + PKV K+ ++K P VPE P+
Sbjct: 4624 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPK---- 4679
Query: 602 EVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPK 661
V E+ VP V E ++P+ K+PE+K P + LP P+ + ++ P
Sbjct: 4680 -----PVEEVEVPTVTKRERKIPE--PTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPP 4731
Query: 662 VPEMKLPKMPEMAVPEV-RLPEVQLPKVSEMKLPKVPEMAVP 702
V P + VP V + E + PK K PK P VP
Sbjct: 4732 VEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAK-PKGPIKGVP 4772
Score = 47.4 bits (111), Expect = 1e-04
Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 22/170 (12%)
Query: 636 LPEVKLPKVPEMAVPDV--HLPEVQLPKVPEMKLPKMPEMAVPEVRLP----EVQLPKVS 689
LPE K E+ + V PE + PKV KL K+ + AVPE P EV++P V+
Sbjct: 4631 LPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVT 4690
Query: 690 --EMKLP---KVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPE 744
E K+P KVPE+ P + LP + E +V +K P ++ P+ +A P V +P
Sbjct: 4691 KRERKIPEPTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPPVE-PEPTPIAAP-VTVPV 4747
Query: 745 VQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEG 794
V K +E + P+ + K PK P +P+ ++A + + G
Sbjct: 4748 V--GKKAEAKAPKEEAAK------PKGPIKGVPKKTPSPIEAERRKLRPG 4789
Score = 47.0 bits (110), Expect = 1e-04
Identities = 53/169 (31%), Positives = 78/169 (46%), Gaps = 13/169 (7%)
Query: 662 VPEMKLPKMPEMAVPEV--RLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKV 719
+PE K E+ + V + PE + PKV KL KV + AVP+ P+ V E++V
Sbjct: 4631 LPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPK----PVEEVEV 4686
Query: 720 PDMKLPEIKLP---KVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKL 776
P + E K+P KVPE+ P + LP + E + ++ P V P A V +
Sbjct: 4687 PTVTKRERKIPEPTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV 4745
Query: 777 P-RAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAG 824
P + + KA K E A+ +PK T P AE + +PG G
Sbjct: 4746 PVVGKKAEAKAPKEEAAKPKGPIKGVPKKT-PSPIEAER-RKLRPGSGG 4792
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 55.8 bits (133), Expect = 3e-07
Identities = 67/215 (31%), Positives = 99/215 (46%), Gaps = 20/215 (9%)
Query: 424 SLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPE 483
+L + V G E KV K + P+ E + K PE P+VE K+ ++K P VPE
Sbjct: 4548 TLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE 4607
Query: 484 MAVPEVRLPEVELPKVS--EMKLP---KVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAV 538
P+ + EVE+P V+ E K+P KVPE+ P + LP + PK PE V
Sbjct: 4608 PPPPK-PVEEVEVPTVTKRERKIPEPTKVPEIK-PAIPLPAPE-------PKPK-PEAEV 4657
Query: 539 PEVRLPEVQ---LPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKL 595
++ P V+ P + + +P V + A + E PK P VP+ K P E +
Sbjct: 4658 KTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAER 4716
Query: 596 PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMK 630
+++ P K P+ A L V L V E+K
Sbjct: 4717 RKLR-PGSGGEKPPDEAPFTYQLKAVPLKFVKEIK 4750
Score = 50.4 bits (119), Expect = 1e-05
Identities = 49/162 (30%), Positives = 73/162 (45%), Gaps = 17/162 (10%)
Query: 545 EVQLPKVSEMKLPEVSEVAVPEVRL---PEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLP 601
E ++ K+ + PE E V + L PE + PKV K+ ++K P VPE P+
Sbjct: 4557 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPK---- 4612
Query: 602 EVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPK 661
V E+ VP V E ++P+ K+PE+K P + LP P+ + ++ P
Sbjct: 4613 -----PVEEVEVPTVTKRERKIPE--PTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPP 4664
Query: 662 VPEMKLPKMPEMAVPEV-RLPEVQLPKVSEMKLPKVPEMAVP 702
V P + VP V + E + PK K PK P VP
Sbjct: 4665 VEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAK-PKGPIKGVP 4705
Score = 47.4 bits (111), Expect = 1e-04
Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 22/170 (12%)
Query: 636 LPEVKLPKVPEMAVPDV--HLPEVQLPKVPEMKLPKMPEMAVPEVRLP----EVQLPKVS 689
LPE K E+ + V PE + PKV KL K+ + AVPE P EV++P V+
Sbjct: 4564 LPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVT 4623
Query: 690 --EMKLP---KVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPE 744
E K+P KVPE+ P + LP + E +V +K P ++ P+ +A P V +P
Sbjct: 4624 KRERKIPEPTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPPVE-PEPTPIAAP-VTVPV 4680
Query: 745 VQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEG 794
V K +E + P+ + K PK P +P+ ++A + + G
Sbjct: 4681 V--GKKAEAKAPKEEAAK------PKGPIKGVPKKTPSPIEAERRKLRPG 4722
Score = 47.0 bits (110), Expect = 1e-04
Identities = 53/169 (31%), Positives = 78/169 (46%), Gaps = 13/169 (7%)
Query: 662 VPEMKLPKMPEMAVPEV--RLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKV 719
+PE K E+ + V + PE + PKV KL KV + AVP+ P+ V E++V
Sbjct: 4564 LPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPK----PVEEVEV 4619
Query: 720 PDMKLPEIKLP---KVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKL 776
P + E K+P KVPE+ P + LP + E + ++ P V P A V +
Sbjct: 4620 PTVTKRERKIPEPTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV 4678
Query: 777 P-RAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAG 824
P + + KA K E A+ +PK T P AE + +PG G
Sbjct: 4679 PVVGKKAEAKAPKEEAAKPKGPIKGVPKKT-PSPIEAER-RKLRPGSGG 4725
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 55.8 bits (133), Expect = 3e-07
Identities = 67/215 (31%), Positives = 99/215 (46%), Gaps = 20/215 (9%)
Query: 424 SLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPE 483
+L + V G E KV K + P+ E + K PE P+VE K+ ++K P VPE
Sbjct: 4423 TLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE 4482
Query: 484 MAVPEVRLPEVELPKVS--EMKLP---KVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAV 538
P+ + EVE+P V+ E K+P KVPE+ P + LP + PK PE V
Sbjct: 4483 PPPPK-PVEEVEVPTVTKRERKIPEPTKVPEIK-PAIPLPAPE-------PKPK-PEAEV 4532
Query: 539 PEVRLPEVQ---LPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKL 595
++ P V+ P + + +P V + A + E PK P VP+ K P E +
Sbjct: 4533 KTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAER 4591
Query: 596 PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMK 630
+++ P K P+ A L V L V E+K
Sbjct: 4592 RKLR-PGSGGEKPPDEAPFTYQLKAVPLKFVKEIK 4625
Score = 50.4 bits (119), Expect = 1e-05
Identities = 49/162 (30%), Positives = 73/162 (45%), Gaps = 17/162 (10%)
Query: 545 EVQLPKVSEMKLPEVSEVAVPEVRL---PEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLP 601
E ++ K+ + PE E V + L PE + PKV K+ ++K P VPE P+
Sbjct: 4432 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPK---- 4487
Query: 602 EVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPK 661
V E+ VP V E ++P+ K+PE+K P + LP P+ + ++ P
Sbjct: 4488 -----PVEEVEVPTVTKRERKIPE--PTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPP 4539
Query: 662 VPEMKLPKMPEMAVPEV-RLPEVQLPKVSEMKLPKVPEMAVP 702
V P + VP V + E + PK K PK P VP
Sbjct: 4540 VEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAK-PKGPIKGVP 4580
Score = 47.4 bits (111), Expect = 1e-04
Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 22/170 (12%)
Query: 636 LPEVKLPKVPEMAVPDV--HLPEVQLPKVPEMKLPKMPEMAVPEVRLP----EVQLPKVS 689
LPE K E+ + V PE + PKV KL K+ + AVPE P EV++P V+
Sbjct: 4439 LPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVT 4498
Query: 690 --EMKLP---KVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPE 744
E K+P KVPE+ P + LP + E +V +K P ++ P+ +A P V +P
Sbjct: 4499 KRERKIPEPTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPPVE-PEPTPIAAP-VTVPV 4555
Query: 745 VQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEG 794
V K +E + P+ + K PK P +P+ ++A + + G
Sbjct: 4556 V--GKKAEAKAPKEEAAK------PKGPIKGVPKKTPSPIEAERRKLRPG 4597
Score = 47.0 bits (110), Expect = 1e-04
Identities = 53/169 (31%), Positives = 78/169 (46%), Gaps = 13/169 (7%)
Query: 662 VPEMKLPKMPEMAVPEV--RLPEVQLPKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMKV 719
+PE K E+ + V + PE + PKV KL KV + AVP+ P+ V E++V
Sbjct: 4439 LPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPK----PVEEVEV 4494
Query: 720 PDMKLPEIKLP---KVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKL 776
P + E K+P KVPE+ P + LP + E + ++ P V P A V +
Sbjct: 4495 PTVTKRERKIPEPTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV 4553
Query: 777 P-RAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAG 824
P + + KA K E A+ +PK T P AE + +PG G
Sbjct: 4554 PVVGKKAEAKAPKEEAAKPKGPIKGVPKKT-PSPIEAER-RKLRPGSGG 4600
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.133 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,437,823
Number of Sequences: 37866
Number of extensions: 3584419
Number of successful extensions: 22406
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 586
Number of HSP's that attempted gapping in prelim test: 15206
Number of HSP's gapped (non-prelim): 3220
length of query: 1461
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1346
effective length of database: 13,892,928
effective search space: 18699881088
effective search space used: 18699881088
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.