Guide to the Human Genome
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Search of human proteins with 116686114

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116686114 kindlin-1 [Homo sapiens]
         (677 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116686114 kindlin-1 [Homo sapiens]                                1363   0.0  
gi|29789006 fermitin family homolog 2 isoform 1 [Homo sapiens]        883   0.0  
gi|201861813 fermitin family homolog 2 isoform 2 [Homo sapiens]       876   0.0  
gi|201861823 fermitin family homolog 2 isoform 3 [Homo sapiens]       800   0.0  
gi|28626504 fermitin family homolog 3 short form [Homo sapiens]       734   0.0  
gi|41281905 fermitin family homolog 3 long form [Homo sapiens]        728   0.0  
gi|223029410 talin 1 [Homo sapiens]                                    64   5e-10
gi|156938343 talin 2 [Homo sapiens]                                    60   5e-09
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva...    39   0.016
gi|239508992 PREDICTED: similar to calcium-promoted Ras inactiva...    39   0.016
gi|121114294 RAS p21 protein activator 4 isoform 1 [Homo sapiens]      39   0.016
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    36   0.13 
gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo sap...    36   0.13 
gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo sap...    36   0.13 
gi|4502435 BMX non-receptor tyrosine kinase [Homo sapiens]             35   0.17 
gi|42544182 BMX non-receptor tyrosine kinase [Homo sapiens]            35   0.17 
gi|149944526 additional sex combs like 3 [Homo sapiens]                34   0.39 
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    34   0.51 
gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Ho...    33   0.66 
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]         33   1.1  
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]         33   1.1  
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]         33   1.1  
gi|21040324 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]         32   1.5  
gi|197927147 B-cell lymphoma 6 protein isoform 2 [Homo sapiens]        32   1.5  
gi|195927002 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]        32   1.5  
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]         32   1.5  
gi|50980301 myosin phosphatase-Rho interacting protein isoform 2...    32   1.5  
gi|50980307 myosin phosphatase-Rho interacting protein isoform 1...    32   1.5  
gi|56549125 dynamin 2 isoform 4 [Homo sapiens]                         32   1.9  
gi|56549123 dynamin 2 isoform 2 [Homo sapiens]                         32   1.9  

>gi|116686114 kindlin-1 [Homo sapiens]
          Length = 677

 Score = 1363 bits (3528), Expect = 0.0
 Identities = 677/677 (100%), Positives = 677/677 (100%)

Query: 1   MLSSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFA 60
           MLSSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFA
Sbjct: 1   MLSSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFA 60

Query: 61  LWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKA 120
           LWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKA
Sbjct: 61  LWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKA 120

Query: 121 VSDICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSP 180
           VSDICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSP
Sbjct: 121 VSDICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSP 180

Query: 181 GLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSL 240
           GLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSL
Sbjct: 181 GLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSL 240

Query: 241 VDKAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAI 300
           VDKAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAI
Sbjct: 241 VDKAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAI 300

Query: 301 LLEEIDCTEEEMLIFAALQYHISKLSLSAETQDFAGESEVDEIEAALSNLEVTLEGGKAD 360
           LLEEIDCTEEEMLIFAALQYHISKLSLSAETQDFAGESEVDEIEAALSNLEVTLEGGKAD
Sbjct: 301 LLEEIDCTEEEMLIFAALQYHISKLSLSAETQDFAGESEVDEIEAALSNLEVTLEGGKAD 360

Query: 361 SLLEDITDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNL 420
           SLLEDITDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNL
Sbjct: 361 SLLEDITDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNL 420

Query: 421 RGCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADS 480
           RGCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADS
Sbjct: 421 RGCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADS 480

Query: 481 SYQPEVLNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAH 540
           SYQPEVLNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAH
Sbjct: 481 SYQPEVLNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAH 540

Query: 541 QNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIP 600
           QNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIP
Sbjct: 541 QNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIP 600

Query: 601 VTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQ 660
           VTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQ
Sbjct: 601 VTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQ 660

Query: 661 NETLDEDLFHKLTGGQD 677
           NETLDEDLFHKLTGGQD
Sbjct: 661 NETLDEDLFHKLTGGQD 677


>gi|29789006 fermitin family homolog 2 isoform 1 [Homo sapiens]
          Length = 680

 Score =  883 bits (2281), Expect = 0.0
 Identities = 429/669 (64%), Positives = 535/669 (79%), Gaps = 11/669 (1%)

Query: 11  SWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALWWEQKHCWL 70
           +WEL V V   N    +DVTLRV+G++H+GGVMLKLVE++++ +DWSD ALWWE+K  WL
Sbjct: 17  TWELSVHVTDLN----RDVTLRVTGEVHIGGVMLKLVEKLDVKKDWSDHALWWEKKRTWL 72

Query: 71  LKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVSDICKILNI 130
           LKTHWTLDKYG+QADAKL FTPQHK+LRL+LPN+K V+++V+FS  VFKAVSDICK  NI
Sbjct: 73  LKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNI 132

Query: 131 RRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSV---SPGLYSKTM 187
           R  EELSLLK   D  KKKKKK  +  E   ++ L LE      GS     SPGLYSKTM
Sbjct: 133 RHPEELSLLKKPRDPTKKKKKKLDDQSE---DEALELEGPLITPGSGSIYSSPGLYSKTM 189

Query: 188 TPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVDKAKLN 247
           TP YD  +G+P S T  WF DS L+E N  ILA SQP  SPE LA M++P++L+DKAK+N
Sbjct: 190 TPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKIN 249

Query: 248 AGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDC 307
            GWLDSSRSLMEQ ++E+E LLLRFKYYSFFDLNPKYDA+RINQLYEQA+WAILLEEI+C
Sbjct: 250 QGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWAILLEEIEC 309

Query: 308 TEEEMLIFAALQYHISKLSL-SAETQDFAGESEVDEIEAALSNLEVTLEGGKADSLLEDI 366
           TEEEM++FAALQYHI+KLS+ ++E      + EVDE++AALS+LE+TLEGGK  ++L DI
Sbjct: 310 TEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDI 369

Query: 367 TDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVV 426
           T IP+LAD +K+F+PKKL  K +KQYW  FKDTSI+ +K+KE   G P  ++NLRGCEV 
Sbjct: 370 TSIPELADYIKVFKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVT 429

Query: 427 PDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEV 486
           PDVN++G+KF IKLLIPVA+GMNE++LRCD+E QYA WMAAC LASKGKTMADSSY  EV
Sbjct: 430 PDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEV 489

Query: 487 LNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAHQNVAQM 546
            NILSFL+M++ N   Q+       D+ PEC VSPR  K++K+KQ+ ARILEAHQNVAQM
Sbjct: 490 QNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQITARILEAHQNVAQM 549

Query: 547 PLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIPVTTWRF 606
            L+EAK+RFIQAWQSLPEFG+T+++ RF+G KK++++G++YNRLI++DA+TG  + TWRF
Sbjct: 550 SLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRF 609

Query: 607 TNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDE 666
           +N+KQWNVNWE + V +EF   V  +F C   DCK+VHE+IGGYIFLSTR+KDQNE+LDE
Sbjct: 610 SNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDE 669

Query: 667 DLFHKLTGG 675
           ++F+KLT G
Sbjct: 670 EMFYKLTSG 678


>gi|201861813 fermitin family homolog 2 isoform 2 [Homo sapiens]
          Length = 687

 Score =  876 bits (2263), Expect = 0.0
 Identities = 429/676 (63%), Positives = 535/676 (79%), Gaps = 18/676 (2%)

Query: 11  SWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALWWEQKHCWL 70
           +WEL V V   N    +DVTLRV+G++H+GGVMLKLVE++++ +DWSD ALWWE+K  WL
Sbjct: 17  TWELSVHVTDLN----RDVTLRVTGEVHIGGVMLKLVEKLDVKKDWSDHALWWEKKRTWL 72

Query: 71  LKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVSDICKILNI 130
           LKTHWTLDKYG+QADAKL FTPQHK+LRL+LPN+K V+++V+FS  VFKAVSDICK  NI
Sbjct: 73  LKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNI 132

Query: 131 RRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSS---VSPGLYSKTM 187
           R  EELSLLK   D  KKKKKK  +  E   ++ L LE      GS     SPGLYSKTM
Sbjct: 133 RHPEELSLLKKPRDPTKKKKKKLDDQSE---DEALELEGPLITPGSGSIYSSPGLYSKTM 189

Query: 188 TPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVDKAKLN 247
           TP YD  +G+P S T  WF DS L+E N  ILA SQP  SPE LA M++P++L+DKAK+N
Sbjct: 190 TPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKIN 249

Query: 248 AGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDC 307
            GWLDSSRSLMEQ ++E+E LLLRFKYYSFFDLNPKYDA+RINQLYEQA+WAILLEEI+C
Sbjct: 250 QGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWAILLEEIEC 309

Query: 308 TEEEMLIFAALQYHISKLS-LSAETQDFAGESEVDEIEAALSNLEVTLEGGKADSLLEDI 366
           TEEEM++FAALQYHI+KLS +++E      + EVDE++AALS+LE+TLEGGK  ++L DI
Sbjct: 310 TEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDI 369

Query: 367 TDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVV 426
           T IP+LAD +K+F+PKKL  K +KQYW  FKDTSI+ +K+KE   G P  ++NLRGCEV 
Sbjct: 370 TSIPELADYIKVFKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVT 429

Query: 427 PDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEV 486
           PDVN++G+KF IKLLIPVA+GMNE++LRCD+E QYA WMAAC LASKGKTMADSSY  EV
Sbjct: 430 PDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEV 489

Query: 487 LNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQ-------LAARILEA 539
            NILSFL+M++ N   Q+       D+ PEC VSPR  K++K+KQ       + ARILEA
Sbjct: 490 QNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQPGYIRDLITARILEA 549

Query: 540 HQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGI 599
           HQNVAQM L+EAK+RFIQAWQSLPEFG+T+++ RF+G KK++++G++YNRLI++DA+TG 
Sbjct: 550 HQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGD 609

Query: 600 PVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKD 659
            + TWRF+N+KQWNVNWE + V +EF   V  +F C   DCK+VHE+IGGYIFLSTR+KD
Sbjct: 610 AIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIGGYIFLSTRAKD 669

Query: 660 QNETLDEDLFHKLTGG 675
           QNE+LDE++F+KLT G
Sbjct: 670 QNESLDEEMFYKLTSG 685


>gi|201861823 fermitin family homolog 2 isoform 3 [Homo sapiens]
          Length = 633

 Score =  800 bits (2067), Expect = 0.0
 Identities = 395/622 (63%), Positives = 492/622 (79%), Gaps = 18/622 (2%)

Query: 11  SWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALWWEQKHCWL 70
           +WEL V V   N    +DVTLRV+G++H+GGVMLKLVE++++ +DWSD ALWWE+K  WL
Sbjct: 17  TWELSVHVTDLN----RDVTLRVTGEVHIGGVMLKLVEKLDVKKDWSDHALWWEKKRTWL 72

Query: 71  LKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVSDICKILNI 130
           LKTHWTLDKYG+QADAKL FTPQHK+LRL+LPN+K V+++V+FS  VFKAVSDICK  NI
Sbjct: 73  LKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNI 132

Query: 131 RRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSS---VSPGLYSKTM 187
           R  EELSLLK   D  KKKKKK  +  E   ++ L LE      GS     SPGLYSKTM
Sbjct: 133 RHPEELSLLKKPRDPTKKKKKKLDDQSE---DEALELEGPLITPGSGSIYSSPGLYSKTM 189

Query: 188 TPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVDKAKLN 247
           TP YD  +G+P S T  WF DS L+E N  ILA SQP  SPE LA M++P++L+DKAK+N
Sbjct: 190 TPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKIN 249

Query: 248 AGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDC 307
            GWLDSSRSLMEQ ++E+E LLLRFKYYSFFDLNPKYDA+RINQLYEQA+WAILLEEI+C
Sbjct: 250 QGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWAILLEEIEC 309

Query: 308 TEEEMLIFAALQYHISKLS-LSAETQDFAGESEVDEIEAALSNLEVTLEGGKADSLLEDI 366
           TEEEM++FAALQYHI+KLS +++E      + EVDE++AALS+LE+TLEGGK  ++L DI
Sbjct: 310 TEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDI 369

Query: 367 TDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVV 426
           T IP+LAD +K+F+PKKL  K +KQYW  FKDTSI+ +K+KE   G P  ++NLRGCEV 
Sbjct: 370 TSIPELADYIKVFKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVT 429

Query: 427 PDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEV 486
           PDVN++G+KF IKLLIPVA+GMNE++LRCD+E QYA WMAAC LASKGKTMADSSY  EV
Sbjct: 430 PDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEV 489

Query: 487 LNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQ-------LAARILEA 539
            NILSFL+M++ N   Q+       D+ PEC VSPR  K++K+KQ       + ARILEA
Sbjct: 490 QNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQPGYIRDLITARILEA 549

Query: 540 HQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGI 599
           HQNVAQM L+EAK+RFIQAWQSLPEFG+T+++ RF+G KK++++G++YNRLI++DA+TG 
Sbjct: 550 HQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGD 609

Query: 600 PVTTWRFTNIKQWNVNWETRQV 621
            + TWRF+N+KQWNVNWE + V
Sbjct: 610 AIKTWRFSNMKQWNVNWEIKMV 631


>gi|28626504 fermitin family homolog 3 short form [Homo sapiens]
          Length = 663

 Score =  734 bits (1895), Expect = 0.0
 Identities = 375/680 (55%), Positives = 495/680 (72%), Gaps = 30/680 (4%)

Query: 3   SSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALW 62
           +S D+  +SWEL V V   + E +  VTLRV+G+ H+GGV+LK+VEQIN  QDWSD A+W
Sbjct: 7   ASGDYIDSSWELRVFVGEEDPEAES-VTLRVTGESHIGGVLLKIVEQINRKQDWSDHAIW 65

Query: 63  WEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVS 122
           WEQK  WLL+THWTLDKYG+ ADA+L F PQH+ + LRLPN + +RLR SFS  +F+AV+
Sbjct: 66  WEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAVA 125

Query: 123 DICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSPGL 182
            IC++L+IR  EELSLL+       +KK+K K  KEP  E++ +L     A G  V+P L
Sbjct: 126 AICRLLSIRHPEELSLLRAP-----EKKEKKKKEKEPE-EELYDLSKVVLAGG--VAPAL 177

Query: 183 YSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVD 242
           +            G PA      FSDS  TE    +L+  QPP  P  L  + +P SL D
Sbjct: 178 F-----------RGMPAH-----FSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSD 221

Query: 243 KAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILL 302
           K +L++ WLDSSR LM+QGI+  + L LRFKYYSFFDL+PK D VR+ QLYEQARW +LL
Sbjct: 222 KTQLHSRWLDSSRCLMQQGIKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLL 281

Query: 303 EEIDCTEEEMLIFAALQYHISKLSLSAETQDFAG-ESEVDEIEAALSNLEVTLEGGKADS 361
           EEIDCTEEEM++FAALQYHI+KLS S E  + AG +  +D+++ ALSNLEV LEG     
Sbjct: 282 EEIDCTEEEMMVFAALQYHINKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTD 341

Query: 362 LLEDITDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLR 421
           +L+ +T IP+L D+L++FRP+KL  K ++Q+W +FK+T+++Y+K+++   G+P+++LNL+
Sbjct: 342 VLDSLTTIPELKDHLRIFRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLK 401

Query: 422 GCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSS 481
           GCEVVPDVNV+G+KF IKLL+P  +GM+E+YLRC  E QYA+WMA C LASKG+TMADSS
Sbjct: 402 GCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSS 461

Query: 482 YQPEVLNILSFLRMKNRNSASQV----ASSLENMDMNPECFVSPRCAKRHKSKQLAARIL 537
           Y  EV  IL+FL ++   S                +NP   V+PR  ++ K+KQL  RIL
Sbjct: 462 YTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRIL 521

Query: 538 EAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAAT 597
           EAHQNVAQ+ L EA+LRFIQAWQSLP+FG++Y +VRFKGS+KD+ILG++ NRLI+ID A 
Sbjct: 522 EAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAV 581

Query: 598 GIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRS 657
           G  V TWRF+N++QWNVNW+ RQV IEFD+++  AF+C+SA C+IVHEYIGGYIFLSTR 
Sbjct: 582 GDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRE 641

Query: 658 KDQNETLDEDLFHKLTGGQD 677
           + + E LDEDLF +LTGG +
Sbjct: 642 RARGEELDEDLFLQLTGGHE 661


>gi|41281905 fermitin family homolog 3 long form [Homo sapiens]
          Length = 667

 Score =  728 bits (1880), Expect = 0.0
 Identities = 375/684 (54%), Positives = 495/684 (72%), Gaps = 34/684 (4%)

Query: 3   SSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALW 62
           +S D+  +SWEL V V   + E +  VTLRV+G+ H+GGV+LK+VEQIN  QDWSD A+W
Sbjct: 7   ASGDYIDSSWELRVFVGEEDPEAES-VTLRVTGESHIGGVLLKIVEQINRKQDWSDHAIW 65

Query: 63  WEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVS 122
           WEQK  WLL+THWTLDKYG+ ADA+L F PQH+ + LRLPN + +RLR SFS  +F+AV+
Sbjct: 66  WEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAVA 125

Query: 123 DICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSPGL 182
            IC++L+IR  EELSLL+       +KK+K K  KEP  E++ +L     A G  V+P L
Sbjct: 126 AICRLLSIRHPEELSLLRAP-----EKKEKKKKEKEPE-EELYDLSKVVLAGG--VAPAL 177

Query: 183 YSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVD 242
           +            G PA      FSDS  TE    +L+  QPP  P  L  + +P SL D
Sbjct: 178 F-----------RGMPAH-----FSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSD 221

Query: 243 KAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILL 302
           K +L++ WLDSSR LM+QGI+  + L LRFKYYSFFDL+PK D VR+ QLYEQARW +LL
Sbjct: 222 KTQLHSRWLDSSRCLMQQGIKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLL 281

Query: 303 EEIDCTEEEMLIFAALQYHISKLSLSAETQDFAG-ESEVDEIEAALSNLEVTLEGGKADS 361
           EEIDCTEEEM++FAALQYHI+KLS S E  + AG +  +D+++ ALSNLEV LEG     
Sbjct: 282 EEIDCTEEEMMVFAALQYHINKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTD 341

Query: 362 LLEDITDIPKLADNLKLFR----PKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEK 417
           +L+ +T IP+L D+L++FR    P+KL  K ++Q+W +FK+T+++Y+K+++   G+P+++
Sbjct: 342 VLDSLTTIPELKDHLRIFRIPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQ 401

Query: 418 LNLRGCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTM 477
           LNL+GCEVVPDVNV+G+KF IKLL+P  +GM+E+YLRC  E QYA+WMA C LASKG+TM
Sbjct: 402 LNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTM 461

Query: 478 ADSSYQPEVLNILSFLRMKNRNSASQV----ASSLENMDMNPECFVSPRCAKRHKSKQLA 533
           ADSSY  EV  IL+FL ++   S                +NP   V+PR  ++ K+KQL 
Sbjct: 462 ADSSYTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLT 521

Query: 534 ARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKI 593
            RILEAHQNVAQ+ L EA+LRFIQAWQSLP+FG++Y +VRFKGS+KD+ILG++ NRLI+I
Sbjct: 522 PRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRI 581

Query: 594 DAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFL 653
           D A G  V TWRF+N++QWNVNW+ RQV IEFD+++  AF+C+SA C+IVHEYIGGYIFL
Sbjct: 582 DLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFL 641

Query: 654 STRSKDQNETLDEDLFHKLTGGQD 677
           STR + + E LDEDLF +LTGG +
Sbjct: 642 STRERARGEELDEDLFLQLTGGHE 665


>gi|223029410 talin 1 [Homo sapiens]
          Length = 2541

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 35/142 (24%), Positives = 76/142 (53%), Gaps = 6/142 (4%)

Query: 525 KRHKSKQLAARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLV--RFKGSKK--D 580
           K +  ++   +I +AH+N  QM  +EAK+R+++  +SL  +G++++LV  + KG  K   
Sbjct: 268 KEYVKQKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVP 327

Query: 581 DILGVSYNRLIKIDAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADC 640
            +LG++   ++++D  T   +  W  TNIK+W  +   +   ++F       ++  + + 
Sbjct: 328 RLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAAS--PKSFTLDFGDYQDGYYSVQTTEG 385

Query: 641 KIVHEYIGGYIFLSTRSKDQNE 662
           + + + I GYI +  + K   +
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKD 407



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 29/73 (39%), Positives = 39/73 (53%)

Query: 250 WLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDCTE 309
           WLD  R+L EQG++E E LLLR K++         D V++N LY QAR  IL      + 
Sbjct: 173 WLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSF 232

Query: 310 EEMLIFAALQYHI 322
           ++   FA  Q  I
Sbjct: 233 DKACEFAGFQCQI 245


>gi|156938343 talin 2 [Homo sapiens]
          Length = 2542

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 31/139 (22%), Positives = 75/139 (53%), Gaps = 6/139 (4%)

Query: 528 KSKQLAARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLV--RFKGSKK--DDIL 583
           K +    RI + H+N  +M  +EAK+++++  +SL  +G++++LV  + KG  K    +L
Sbjct: 274 KQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLL 333

Query: 584 GVSYNRLIKIDAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIV 643
           G++ + ++++D  T   +  W  T +K+W  +   +   ++F +   + ++  + + + +
Sbjct: 334 GITKDSVMRVDEKTKEVLQEWPLTTVKRWAAS--PKSFTLDFGEYQESYYSVQTTEGEQI 391

Query: 644 HEYIGGYIFLSTRSKDQNE 662
            + I GYI +  + K   +
Sbjct: 392 SQLIAGYIDIILKKKQSKD 410



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 33/84 (39%), Positives = 43/84 (51%), Gaps = 4/84 (4%)

Query: 243 KAKLNA----GWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARW 298
           KAKL+      WLD SR+  EQG+ E+E LLLR K++         D V++N LY QAR 
Sbjct: 164 KAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARD 223

Query: 299 AILLEEIDCTEEEMLIFAALQYHI 322
            IL      + E+   F   Q  I
Sbjct: 224 DILNGSHPVSFEKACEFGGFQAQI 247


>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
           isoform 2 [Homo sapiens]
          Length = 731

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 24/103 (23%), Positives = 44/103 (42%)

Query: 384 LLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNVAGRKFGIKLLIP 443
           L+  +FK+ +F     ++++ K    ++   ++  N+R  E V + +  G      +   
Sbjct: 512 LMSSSFKKLYFSLTTEALSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTD 571

Query: 444 VADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEV 486
            A      YL+C   N+  QW++A    S   T    SY P V
Sbjct: 572 DAGRPQTAYLQCKCVNELNQWLSALRKVSINNTGLLGSYHPGV 614


>gi|239508992 PREDICTED: similar to calcium-promoted Ras inactivator
           isoform 1 [Homo sapiens]
          Length = 731

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 24/103 (23%), Positives = 44/103 (42%)

Query: 384 LLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNVAGRKFGIKLLIP 443
           L+  +FK+ +F     ++++ K    ++   ++  N+R  E V + +  G      +   
Sbjct: 512 LMSSSFKKLYFSLTTEALSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTD 571

Query: 444 VADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEV 486
            A      YL+C   N+  QW++A    S   T    SY P V
Sbjct: 572 DAGRPQTAYLQCKCVNELNQWLSALRKVSINNTGLLGSYHPGV 614


>gi|121114294 RAS p21 protein activator 4 isoform 1 [Homo sapiens]
          Length = 803

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 24/103 (23%), Positives = 44/103 (42%)

Query: 384 LLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNVAGRKFGIKLLIP 443
           L+  +FK+ +F     ++++ K    ++   ++  N+R  E V + +  G      +   
Sbjct: 584 LMSSSFKKLYFSLTTEALSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTD 643

Query: 444 VADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEV 486
            A      YL+C   N+  QW++A    S   T    SY P V
Sbjct: 644 DAGRPQTAYLQCKCVNELNQWLSALRKVSINNTGLLGSYHPGV 686


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 15/53 (28%), Positives = 34/53 (64%), Gaps = 2/53 (3%)

Query: 389  FKQYWFIFKDTSIAYFKNKELEQGEPLE-KLNLRGCEVVPDVNVAGRKFGIKL 440
            +K++WF+  D+S+ Y+++   E+ + L+ +++LR C  V +  V  R +G ++
Sbjct: 1807 WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQ-RNYGFQI 1858


>gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 15/53 (28%), Positives = 34/53 (64%), Gaps = 2/53 (3%)

Query: 389 FKQYWFIFKDTSIAYFKNKELEQGEPLE-KLNLRGCEVVPDVNVAGRKFGIKL 440
           +K++WF+  D+S+ Y+++   E+ + L+ +++LR C  V +  V  R +G ++
Sbjct: 94  WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQ-RNYGFQI 145


>gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo
           sapiens]
          Length = 652

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 15/53 (28%), Positives = 34/53 (64%), Gaps = 2/53 (3%)

Query: 389 FKQYWFIFKDTSIAYFKNKELEQGEPLE-KLNLRGCEVVPDVNVAGRKFGIKL 440
           +K++WF+  D+S+ Y+++   E+ + L+ +++LR C  V +  V  R +G ++
Sbjct: 94  WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQ-RNYGFQI 145


>gi|4502435 BMX non-receptor tyrosine kinase [Homo sapiens]
          Length = 675

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 20/98 (20%), Positives = 49/98 (50%), Gaps = 9/98 (9%)

Query: 382 KKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNV-----AGRKF 436
           KK+ P  +K+  F+   T+++Y++  ++++G     + ++    V  VN+       R++
Sbjct: 19  KKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQY 78

Query: 437 GIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKG 474
             +++    DG+  +Y+   +E   +QW+ A     +G
Sbjct: 79  PFQIV--YKDGL--LYVYASNEESRSQWLKALQKEIRG 112


>gi|42544182 BMX non-receptor tyrosine kinase [Homo sapiens]
          Length = 675

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 20/98 (20%), Positives = 49/98 (50%), Gaps = 9/98 (9%)

Query: 382 KKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNV-----AGRKF 436
           KK+ P  +K+  F+   T+++Y++  ++++G     + ++    V  VN+       R++
Sbjct: 19  KKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQY 78

Query: 437 GIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKG 474
             +++    DG+  +Y+   +E   +QW+ A     +G
Sbjct: 79  PFQIV--YKDGL--LYVYASNEESRSQWLKALQKEIRG 112


>gi|149944526 additional sex combs like 3 [Homo sapiens]
          Length = 2248

 Score = 34.3 bits (77), Expect = 0.39
 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 144 DYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSPGLYSKTMTPIYDPINGTPASSTM 203
           D + ++   D+N    ++ +I  + +SP  S +S+   L    +T    P++  P +S  
Sbjct: 660 DKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNL---PLTSEASPVSNLPLTSET 716

Query: 204 TWFSDSPLTEQNCSI 218
           +  SD PLT +  S+
Sbjct: 717 SPMSDLPLTSETSSV 731


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 33.9 bits (76), Expect = 0.51
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 7/94 (7%)

Query: 169 SSPTASGSSV----SPGLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQP 224
           +SPT S S+     SP   + T TP    +  TP+ +++T  S + LT    ++L    P
Sbjct: 527 ASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMP 586

Query: 225 PQ-SPEALADMYQPRSLVDKAKLNAGWLDSSRSL 257
           P  SP  +     P  +   A L    +DS+ S+
Sbjct: 587 PSASPTGMPSRTSPTGMPSSALLTK--MDSTASI 618


>gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Homo
           sapiens]
          Length = 1034

 Score = 33.5 bits (75), Expect = 0.66
 Identities = 21/98 (21%), Positives = 42/98 (42%), Gaps = 16/98 (16%)

Query: 382 KKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNV-----AGRKF 436
           K    + +K+YWF+ KD S+ ++ N+E E+ E        G   +P+  +       +K+
Sbjct: 584 KSYFSQKWKKYWFVLKDASLYWYINEEDEKAE--------GFISLPEFKIDRASECRKKY 635

Query: 437 GIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKG 474
             K   P    +   Y   +H +   +W+    + + G
Sbjct: 636 AFKACHP---KIKSFYFAAEHLDDMNRWLNRINMLTAG 670


>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
          Length = 1072

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 11/87 (12%)

Query: 148  KKKKKDKNNKEPIIEDILNLESSPTASG--SSVSPGLYSKTMTPIYDPINGTPASSTMT- 204
            KK KK+K +K+P+   I+ +E+S        SV+  L        Y  +NG P S  +  
Sbjct: 935  KKDKKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLAR 994

Query: 205  -WFSDSPLTEQNCSILAFSQPPQSPEA 230
             + S SPL             PQSP A
Sbjct: 995  HYKSSSPLP-------TVQLHPQSPTA 1014


>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
          Length = 1200

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 11/87 (12%)

Query: 148 KKKKKDKNNKEPIIEDILNLESSPTASG--SSVSPGLYSKTMTPIYDPINGTPASSTMT- 204
           KK KK+K +K+P+   I+ +E+S        SV+  L        Y  +NG P S  +  
Sbjct: 888 KKDKKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLAR 947

Query: 205 -WFSDSPLTEQNCSILAFSQPPQSPEA 230
            + S SPL             PQSP A
Sbjct: 948 HYKSSSPLP-------TVQLHPQSPTA 967


>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
          Length = 1069

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 11/87 (12%)

Query: 148  KKKKKDKNNKEPIIEDILNLESSPTASG--SSVSPGLYSKTMTPIYDPINGTPASSTMT- 204
            KK KK+K +K+P+   I+ +E+S        SV+  L        Y  +NG P S  +  
Sbjct: 935  KKDKKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLAR 994

Query: 205  -WFSDSPLTEQNCSILAFSQPPQSPEA 230
             + S SPL             PQSP A
Sbjct: 995  HYKSSSPLP-------TVQLHPQSPTA 1014


>gi|21040324 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]
          Length = 706

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 10/119 (8%)

Query: 98  RLRLPNLKMVRLRVSFSAVVFKAVSDIC-KILNIRRSEELSLLKPSGDYFKKKKKKDKNN 156
           RL L    ++ +  +   +  + V D C K +    +E +S +KP  + F   +     +
Sbjct: 94  RLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVSAIKPPREEFLNSRMLMPQD 153

Query: 157 -----KEPIIEDILNLESSPTASGSSVSPGLYSKTMTP--IYDPINGTPASSTMTWFSD 208
                   ++E+ L L S+P     + +P LYS   TP   Y   +  P SS +  FSD
Sbjct: 154 IMAYRGREVVENNLPLRSAPGCESRAFAPSLYSGLSTPPASYSMYSHLPVSSLL--FSD 210


>gi|197927147 B-cell lymphoma 6 protein isoform 2 [Homo sapiens]
          Length = 650

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 10/119 (8%)

Query: 98  RLRLPNLKMVRLRVSFSAVVFKAVSDIC-KILNIRRSEELSLLKPSGDYFKKKKKKDKNN 156
           RL L    ++ +  +   +  + V D C K +    +E +S +KP  + F   +     +
Sbjct: 94  RLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVSAIKPPREEFLNSRMLMPQD 153

Query: 157 -----KEPIIEDILNLESSPTASGSSVSPGLYSKTMTP--IYDPINGTPASSTMTWFSD 208
                   ++E+ L L S+P     + +P LYS   TP   Y   +  P SS +  FSD
Sbjct: 154 IMAYRGREVVENNLPLRSAPGCESRAFAPSLYSGLSTPPASYSMYSHLPVSSLL--FSD 210


>gi|195927002 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]
          Length = 706

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 10/119 (8%)

Query: 98  RLRLPNLKMVRLRVSFSAVVFKAVSDIC-KILNIRRSEELSLLKPSGDYFKKKKKKDKNN 156
           RL L    ++ +  +   +  + V D C K +    +E +S +KP  + F   +     +
Sbjct: 94  RLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVSAIKPPREEFLNSRMLMPQD 153

Query: 157 -----KEPIIEDILNLESSPTASGSSVSPGLYSKTMTP--IYDPINGTPASSTMTWFSD 208
                   ++E+ L L S+P     + +P LYS   TP   Y   +  P SS +  FSD
Sbjct: 154 IMAYRGREVVENNLPLRSAPGCESRAFAPSLYSGLSTPPASYSMYSHLPVSSLL--FSD 210


>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
          Length = 1060

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 44/172 (25%), Positives = 71/172 (41%), Gaps = 31/172 (18%)

Query: 131  RRSEELSLLKPSGDYFKKKKKKDKNNKEP------IIEDILNLESSPTASGSSVSPGLYS 184
            + +++L   KPSG   K  K K K +K P        ED   L+ S   +  S +PG   
Sbjct: 891  KETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPG--- 947

Query: 185  KTMTPIYDPINGTPASSTM--TWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVD 242
                 I+ P+N  P S  +   + S+SPL        +    PQSP A +  +Q    + 
Sbjct: 948  -DSPRIHLPLNYPPGSPDLGRHYRSNSPLP-------SIQLQPQSPSA-SKKHQVVQDLP 998

Query: 243  KAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYE 294
             A    G  D++ +  EQ           +  YS+    PKY + ++ Q ++
Sbjct: 999  PANTFVGTGDTTSTGSEQ-----------YSDYSYRTNPPKYPSKQVGQPFQ 1039


>gi|50980301 myosin phosphatase-Rho interacting protein isoform 2
           [Homo sapiens]
          Length = 1025

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 3/111 (2%)

Query: 332 QDFAGESEVDEI-EAALSNLEVTLEGGKADSLLEDITDIPKLADNLKLFRPKKLLPKAFK 390
           +DF  E+    + +A+ S L         D    + +  P L +  K +  K+     +K
Sbjct: 345 RDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWK 404

Query: 391 QYWFIFKDTSIAYFKNKELEQGEPLE-KLNLRGCEVVPDVNVAGRKFGIKL 440
           ++WF+  D S+ Y+++   E+   L+ +++L  C  V +  V  R +G ++
Sbjct: 405 KHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQ-RNYGFQI 454


>gi|50980307 myosin phosphatase-Rho interacting protein isoform 1
           [Homo sapiens]
          Length = 1038

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 3/111 (2%)

Query: 332 QDFAGESEVDEI-EAALSNLEVTLEGGKADSLLEDITDIPKLADNLKLFRPKKLLPKAFK 390
           +DF  E+    + +A+ S L         D    + +  P L +  K +  K+     +K
Sbjct: 345 RDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWK 404

Query: 391 QYWFIFKDTSIAYFKNKELEQGEPLE-KLNLRGCEVVPDVNVAGRKFGIKL 440
           ++WF+  D S+ Y+++   E+   L+ +++L  C  V +  V  R +G ++
Sbjct: 405 KHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQ-RNYGFQI 454


>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
          Length = 866

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 19/99 (19%)

Query: 384 LLPKAFKQYWFIFKDTSIAYFKNKELEQGE---PLEKLNLRGCE--------VVPDVNVA 432
           L+    K+YWF+    S++++K++E ++ +   PL+ L +R  E        V    N  
Sbjct: 529 LMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTE 588

Query: 433 GRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLA 471
            R         V   + ++ L CD +     W A+ + A
Sbjct: 589 QRN--------VYKDLRQIELACDSQEDVDSWKASFLRA 619


>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
          Length = 870

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 19/99 (19%)

Query: 384 LLPKAFKQYWFIFKDTSIAYFKNKELEQGE---PLEKLNLRGCE--------VVPDVNVA 432
           L+    K+YWF+    S++++K++E ++ +   PL+ L +R  E        V    N  
Sbjct: 533 LMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTE 592

Query: 433 GRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLA 471
            R         V   + ++ L CD +     W A+ + A
Sbjct: 593 QRN--------VYKDLRQIELACDSQEDVDSWKASFLRA 623


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,820,491
Number of Sequences: 37866
Number of extensions: 1079912
Number of successful extensions: 3103
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 3035
Number of HSP's gapped (non-prelim): 89
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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