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Search of human proteins with 116534937
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116534937 interferon-induced protein with tetratricopeptide
repeats 1 isoform 2 [Homo sapiens]
(478 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116534937 interferon-induced protein with tetratricopeptide r... 961 0.0
gi|58330892 interferon-induced protein with tetratricopeptide re... 652 0.0
gi|6912630 interferon-induced protein with tetratricopeptide rep... 538 e-153
gi|153082755 interferon-induced protein with tetratricopeptide r... 397 e-111
gi|31542980 interferon-induced protein with tetratricopeptide re... 363 e-100
gi|72534658 interferon-induced protein with tetratricopeptide re... 363 e-100
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 59 1e-08
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 59 1e-08
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 53 5e-07
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 50 3e-06
gi|83415184 transmembrane and tetratricopeptide repeat containin... 49 1e-05
gi|22749211 transmembrane and tetratricopeptide repeat containin... 47 3e-05
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 47 4e-05
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 45 2e-04
gi|239741018 PREDICTED: hypothetical protein XP_002342056 [Homo ... 39 0.014
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 38 0.018
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 37 0.030
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 37 0.030
gi|225735631 mesoderm induction early response 1 isoform g [Homo... 37 0.030
gi|225735615 mesoderm induction early response 1 isoform a [Homo... 37 0.030
gi|118130872 mesoderm induction early response 1 isoform f [Homo... 37 0.030
gi|225735612 mesoderm induction early response 1 isoform e [Homo... 37 0.030
gi|225735610 mesoderm induction early response 1 isoform d [Homo... 37 0.030
gi|118130815 mesoderm induction early response 1 isoform c [Homo... 37 0.030
gi|225735607 mesoderm induction early response 1 isoform b [Homo... 37 0.030
gi|225735605 mesoderm induction early response 1 isoform a [Homo... 37 0.030
gi|118402578 anaphase-promoting complex, subunit 6 [Homo sapiens] 37 0.030
gi|118402580 anaphase-promoting complex, subunit 6 [Homo sapiens] 37 0.030
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho... 37 0.039
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 37 0.052
>gi|116534937 interferon-induced protein with tetratricopeptide
repeats 1 isoform 2 [Homo sapiens]
Length = 478
Score = 961 bits (2485), Expect = 0.0
Identities = 478/478 (100%), Positives = 478/478 (100%)
Query: 1 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60
MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY
Sbjct: 1 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60
Query: 61 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120
VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK
Sbjct: 61 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120
Query: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180
VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG
Sbjct: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180
Query: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 240
YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI
Sbjct: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 240
Query: 241 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 300
EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI
Sbjct: 241 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 300
Query: 301 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360
QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE
Sbjct: 301 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360
Query: 361 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 420
ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN
Sbjct: 361 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 420
Query: 421 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 478
SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP
Sbjct: 421 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 478
>gi|58330892 interferon-induced protein with tetratricopeptide
repeats 1-like [Homo sapiens]
Length = 474
Score = 652 bits (1681), Expect = 0.0
Identities = 319/469 (68%), Positives = 386/469 (82%)
Query: 1 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60
MS D ++DSL QLRCHFTW+L I+ E+PDLENR+ ++I+FLDTKY+VGIHNLLAY
Sbjct: 1 MSEESDGKLIEDSLIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAY 60
Query: 61 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120
VKHLKGQNEEAL SLK+AE+L+Q+EH NQA++RSLVTWGNFAW+YYHMGRLAEAQTYLDK
Sbjct: 61 VKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDK 120
Query: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180
VEN CKK +NP RYRMECPE+DCEEGWAL KCGGKNYERAK CFEK LE +PENPE + G
Sbjct: 121 VENTCKKFANPSRYRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTG 180
Query: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 240
YAI+ YRLD F A+ +K FSL L++AVRLNPD+ YI+VLLALKLQDEGQEAEGEKYI
Sbjct: 181 YAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYI 240
Query: 241 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 300
EEAL ++SSQ YVF+YAAKFYRRKGSVDKALELLK AL+ TPTS LHHQ+GLCY+AQMI
Sbjct: 241 EEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMI 300
Query: 301 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360
QIKEAT QPRGQ+RE +D++++ AI FE + K TFE+A++DLA Y E G+HRKAE
Sbjct: 301 QIKEATNWQPRGQDRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAE 360
Query: 361 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 420
E+FQK L MK ++ Q+IH+HYGRFQE KS AI HYLK +KIE+ S +R+K +N
Sbjct: 361 EHFQKGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLN 420
Query: 421 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAAD 469
+L+KL R + + +ES+SLLG ++KL+G +++AL YERALRLAAD
Sbjct: 421 ALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERALRLAAD 469
>gi|6912630 interferon-induced protein with tetratricopeptide
repeats 5 [Homo sapiens]
Length = 482
Score = 538 bits (1385), Expect = e-153
Identities = 266/464 (57%), Positives = 351/464 (75%), Gaps = 3/464 (0%)
Query: 10 VKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNE 69
+K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAYVKHLKGQN+
Sbjct: 9 LKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNK 68
Query: 70 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 129
+AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K+ N+CKKLS
Sbjct: 69 DALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLS 128
Query: 130 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 189
+P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + GYAI+ YRLD
Sbjct: 129 SPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLD 188
Query: 190 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 249
+ K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYIEE L +SS
Sbjct: 189 DSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISS 247
Query: 250 QTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQ 309
Q YV RYAAKFYRRK S +KALELLKKAL+ TPTS LHHQ+GLCY+AQMIQIK+AT +
Sbjct: 248 QPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNR 307
Query: 310 PRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 369
P+G+++ K+D++I SAIFHF++A+E+ F A+ DLA MY E G + AE+ F+K L +
Sbjct: 308 PKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367
Query: 370 KPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRK 429
+ + ++ IH+HYGRFQEF +KS+ AI HYL+A+K++ S R K ++LKKL ++
Sbjct: 368 ENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKR 427
Query: 430 LRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473
L ALD++SLS LGFVYKLEG +A EYYE+A ++ D EN+
Sbjct: 428 LCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKI--DPENA 469
>gi|153082755 interferon-induced protein with tetratricopeptide
repeats 2 [Homo sapiens]
Length = 472
Score = 397 bits (1021), Expect = e-111
Identities = 217/469 (46%), Positives = 304/469 (64%), Gaps = 17/469 (3%)
Query: 1 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60
MS N + + ++ SL QL+CHFTW L ++ + D E++V + EF + ++ + NLLAY
Sbjct: 1 MSEN-NKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAY 59
Query: 61 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120
+KHLKGQNE AL+ L++AE L+Q+EH +QA +RSLVTWGN+AW+YYHMGRL++ Q Y+DK
Sbjct: 60 LKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDK 119
Query: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180
V+++C+K S+P YR+E PE+DCEEGW LKCGG ERAK CFEK LE P+NPE ++G
Sbjct: 120 VKHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSG 177
Query: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKL---QDEG-QEAEG 236
AI++YRLD + + ++ PLRQA+RLNPDN Y+KVLLALKL ++EG +E EG
Sbjct: 178 LAIASYRLDNWPPSQN-----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEG 232
Query: 237 EKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYK 296
EK +EEAL T V R AAKFYRRK DKA+ELLKKAL+ P + LH QIG CY+
Sbjct: 233 EKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYR 292
Query: 297 AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPT-FEVAHLDLARMYIEAGN 355
A++ Q+ + G + KL ++I A+ H + A E F V + LA ++ A
Sbjct: 293 AKVFQVMNLRENGMYG--KRKLLELIGHAVAHLKKADEANDNLFRVCSI-LASLHALADQ 349
Query: 356 HRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR 415
+ AE FQK K + Q +H YG FQ +Q K + AI H+++ +KI Q S +
Sbjct: 350 YEDAEYYFQKEF-SKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREK 408
Query: 416 DKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL 464
+K + L+K+ +L + D E+L +L F+ +L M +A E ER L
Sbjct: 409 EKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGL 457
>gi|31542980 interferon-induced protein with tetratricopeptide
repeats 3 [Homo sapiens]
Length = 490
Score = 363 bits (933), Expect = e-100
Identities = 207/471 (43%), Positives = 292/471 (61%), Gaps = 30/471 (6%)
Query: 11 KDSLE----QLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG 66
K+SLE QL+CHFTW L +D DLE+RV +QIEFL+T++ ++NLLAY+KHL G
Sbjct: 6 KNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDG 65
Query: 67 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK 126
NE AL+ L++AE L+Q+EH +QA +RSLVTWGN+AW+YYH+GRL++AQ Y+DKV+ CK
Sbjct: 66 NNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCK 125
Query: 127 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 186
K SNP Y +E E+DCEEGW LKCG ERAK CFEK LE P NPE S+G AI+ Y
Sbjct: 126 KFSNP--YSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSGLAIAMY 181
Query: 187 RLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEAL 244
LD NH K FS L+QA+ L+PDN Y+KVLL LKLQ +EAEGE+++EEAL
Sbjct: 182 HLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEAL 234
Query: 245 ANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKE 304
QT V R AAKFYRRKG +DKA+EL ++ L+ TP + L+HQIG CYKA++ Q++
Sbjct: 235 EKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQN 294
Query: 305 ATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQ 364
+ + G N+E ++ + + A+ + A+EK A+ DLA E
Sbjct: 295 TGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEF---------LETECY 344
Query: 365 KLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKK 424
+ K V + Q H Y Q++ KS+ A+ H L+ + I + S +++ + +
Sbjct: 345 QTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQN 404
Query: 425 LVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENSV 474
+ L + A + L G ++K G++ +A + YE+ L RL D + +
Sbjct: 405 VSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSGI 453
>gi|72534658 interferon-induced protein with tetratricopeptide
repeats 3 [Homo sapiens]
Length = 490
Score = 363 bits (933), Expect = e-100
Identities = 207/471 (43%), Positives = 292/471 (61%), Gaps = 30/471 (6%)
Query: 11 KDSLE----QLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG 66
K+SLE QL+CHFTW L +D DLE+RV +QIEFL+T++ ++NLLAY+KHL G
Sbjct: 6 KNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDG 65
Query: 67 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK 126
NE AL+ L++AE L+Q+EH +QA +RSLVTWGN+AW+YYH+GRL++AQ Y+DKV+ CK
Sbjct: 66 NNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCK 125
Query: 127 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 186
K SNP Y +E E+DCEEGW LKCG ERAK CFEK LE P NPE S+G AI+ Y
Sbjct: 126 KFSNP--YSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSGLAIAMY 181
Query: 187 RLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEAL 244
LD NH K FS L+QA+ L+PDN Y+KVLL LKLQ +EAEGE+++EEAL
Sbjct: 182 HLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEAL 234
Query: 245 ANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKE 304
QT V R AAKFYRRKG +DKA+EL ++ L+ TP + L+HQIG CYKA++ Q++
Sbjct: 235 EKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQN 294
Query: 305 ATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQ 364
+ + G N+E ++ + + A+ + A+EK A+ DLA E
Sbjct: 295 TGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEF---------LETECY 344
Query: 365 KLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKK 424
+ K V + Q H Y Q++ KS+ A+ H L+ + I + S +++ + +
Sbjct: 345 QTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQN 404
Query: 425 LVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENSV 474
+ L + A + L G ++K G++ +A + YE+ L RL D + +
Sbjct: 405 VSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSGI 453
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 58.9 bits (141), Expect = 1e-08
Identities = 67/315 (21%), Positives = 124/315 (39%), Gaps = 35/315 (11%)
Query: 70 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 129
+AL L+EA+ + + Q N V W N ++ G + A + +K +
Sbjct: 158 KALGRLEEAKACYLKAIETQPNFA--VAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF- 214
Query: 130 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 189
+D + + ++RA A + + L + P + A Y
Sbjct: 215 -----------LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQG 263
Query: 190 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 249
LA + R+A+ L P LA L+++G AE E AL +
Sbjct: 264 LIDLAIDTY--------RRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 315
Query: 250 QTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ------MIQIK 303
A R +G++++A+ L +KAL+ P H + + Q ++ K
Sbjct: 316 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 375
Query: 304 EATKGQPRGQ-------NREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNH 356
EA + P N K + ++ A+ + A++ P F AH +LA ++ ++GN
Sbjct: 376 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 435
Query: 357 RKAEENFQKLLCMKP 371
+A +++ L +KP
Sbjct: 436 PEAIASYRTALKLKP 450
Score = 51.6 bits (122), Expect = 2e-06
Identities = 97/428 (22%), Positives = 172/428 (40%), Gaps = 83/428 (19%)
Query: 65 KGQNEEALKSLKEAENLMQEEHDNQANVRS-LVTWGNFAWMYYHMGRLAEAQTYLDKVEN 123
+GQ +EA++ + A L + D N+ + LV G+ Q Y+ ++
Sbjct: 92 RGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME---------GAVQAYVSALQY 142
Query: 124 ICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAI 183
NP Y C D LLK G+ E AKAC+ K +E P +A+
Sbjct: 143 ------NPDLY---CVRSDLGN---LLKALGR-LEEAKACYLKAIETQPN-------FAV 182
Query: 184 SAYRLDGFKLATKNHKPFSLLPLRQAVRLNPD--NGYIK---VLLALKLQDEGQEAEGEK 238
+ L G + ++ +AV L+P+ + YI VL ++ D A
Sbjct: 183 AWSNL-GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAA---- 237
Query: 239 YIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ 298
Y+ AL+ + V A Y +G +D A++ ++A++ P H C A
Sbjct: 238 YLR-ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP-----HFPDAYCNLAN 291
Query: 299 MIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRK 358
++ K + + A + +A+ PT + +LA + E GN +
Sbjct: 292 ALKEKGS----------------VAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEE 335
Query: 359 AEENFQKLLCMKP---VVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR 415
A ++K L + P + + G+ QE A++HY +AI+I
Sbjct: 336 AVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE--------ALMHYKEAIRISPTFADA 387
Query: 416 DKSI-NSLKKL---------VLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALR 465
++ N+LK++ R ++ ++ S L ++K GN+ EA+ Y AL+
Sbjct: 388 YSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALK 447
Query: 466 LAADFENS 473
L DF ++
Sbjct: 448 LKPDFPDA 455
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 388 QEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVY 447
Q ++++ D ++ L +I + L R ++L +++ L E+ S LG VY
Sbjct: 36 QLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLA------IKQNPLLAEAYSNLGNVY 89
Query: 448 KLEGNMNEALEYYERALRLAADF 470
K G + EA+E+Y ALRL DF
Sbjct: 90 KERGQLQEAIEHYRHALRLKPDF 112
Score = 34.3 bits (77), Expect = 0.26
Identities = 58/290 (20%), Positives = 107/290 (36%), Gaps = 60/290 (20%)
Query: 223 LALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETP 282
LA + G E++ + T V + + + +D++ A+++ P
Sbjct: 17 LAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNP 76
Query: 283 TSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVA 342
+ +G YK RGQ +E AI H+ A+ KP F
Sbjct: 77 LLAEAYSNLGNVYKE-------------RGQLQE--------AIEHYRHALRLKPDFIDG 115
Query: 343 HLDLARMYIEAGNHRKAEENFQKLLCMKP---VVEETMQDIHFHYGRFQE---------- 389
+++LA + AG+ A + + L P V + ++ GR +E
Sbjct: 116 YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIE 175
Query: 390 ---------------FQKKSDV-NAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRK 433
F + ++ AI H+ KA+ ++ L ++ ++ K R
Sbjct: 176 TQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAV 235
Query: 434 ALDLESLSL----------LGFVYKLEGNMNEALEYYERALRLAADFENS 473
A L +LSL L VY +G ++ A++ Y RA+ L F ++
Sbjct: 236 AAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDA 285
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 58.9 bits (141), Expect = 1e-08
Identities = 67/315 (21%), Positives = 124/315 (39%), Gaps = 35/315 (11%)
Query: 70 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 129
+AL L+EA+ + + Q N V W N ++ G + A + +K +
Sbjct: 168 KALGRLEEAKACYLKAIETQPNFA--VAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF- 224
Query: 130 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 189
+D + + ++RA A + + L + P + A Y
Sbjct: 225 -----------LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQG 273
Query: 190 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 249
LA + R+A+ L P LA L+++G AE E AL +
Sbjct: 274 LIDLAIDTY--------RRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 325
Query: 250 QTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ------MIQIK 303
A R +G++++A+ L +KAL+ P H + + Q ++ K
Sbjct: 326 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 385
Query: 304 EATKGQPRGQ-------NREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNH 356
EA + P N K + ++ A+ + A++ P F AH +LA ++ ++GN
Sbjct: 386 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 445
Query: 357 RKAEENFQKLLCMKP 371
+A +++ L +KP
Sbjct: 446 PEAIASYRTALKLKP 460
Score = 51.6 bits (122), Expect = 2e-06
Identities = 97/428 (22%), Positives = 172/428 (40%), Gaps = 83/428 (19%)
Query: 65 KGQNEEALKSLKEAENLMQEEHDNQANVRS-LVTWGNFAWMYYHMGRLAEAQTYLDKVEN 123
+GQ +EA++ + A L + D N+ + LV G+ Q Y+ ++
Sbjct: 102 RGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME---------GAVQAYVSALQY 152
Query: 124 ICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAI 183
NP Y C D LLK G+ E AKAC+ K +E P +A+
Sbjct: 153 ------NPDLY---CVRSDLGN---LLKALGR-LEEAKACYLKAIETQPN-------FAV 192
Query: 184 SAYRLDGFKLATKNHKPFSLLPLRQAVRLNPD--NGYIK---VLLALKLQDEGQEAEGEK 238
+ L G + ++ +AV L+P+ + YI VL ++ D A
Sbjct: 193 AWSNL-GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAA---- 247
Query: 239 YIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ 298
Y+ AL+ + V A Y +G +D A++ ++A++ P H C A
Sbjct: 248 YLR-ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP-----HFPDAYCNLAN 301
Query: 299 MIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRK 358
++ K + + A + +A+ PT + +LA + E GN +
Sbjct: 302 ALKEKGS----------------VAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEE 345
Query: 359 AEENFQKLLCMKP---VVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR 415
A ++K L + P + + G+ QE A++HY +AI+I
Sbjct: 346 AVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE--------ALMHYKEAIRISPTFADA 397
Query: 416 DKSI-NSLKKL---------VLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALR 465
++ N+LK++ R ++ ++ S L ++K GN+ EA+ Y AL+
Sbjct: 398 YSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALK 457
Query: 466 LAADFENS 473
L DF ++
Sbjct: 458 LKPDFPDA 465
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 388 QEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVY 447
Q ++++ D ++ L +I + L R ++L +++ L E+ S LG VY
Sbjct: 46 QLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLA------IKQNPLLAEAYSNLGNVY 99
Query: 448 KLEGNMNEALEYYERALRLAADF 470
K G + EA+E+Y ALRL DF
Sbjct: 100 KERGQLQEAIEHYRHALRLKPDF 122
Score = 34.3 bits (77), Expect = 0.26
Identities = 58/290 (20%), Positives = 107/290 (36%), Gaps = 60/290 (20%)
Query: 223 LALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETP 282
LA + G E++ + T V + + + +D++ A+++ P
Sbjct: 27 LAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNP 86
Query: 283 TSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVA 342
+ +G YK RGQ +E AI H+ A+ KP F
Sbjct: 87 LLAEAYSNLGNVYKE-------------RGQLQE--------AIEHYRHALRLKPDFIDG 125
Query: 343 HLDLARMYIEAGNHRKAEENFQKLLCMKP---VVEETMQDIHFHYGRFQE---------- 389
+++LA + AG+ A + + L P V + ++ GR +E
Sbjct: 126 YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIE 185
Query: 390 ---------------FQKKSDV-NAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRK 433
F + ++ AI H+ KA+ ++ L ++ ++ K R
Sbjct: 186 TQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAV 245
Query: 434 ALDLESLSL----------LGFVYKLEGNMNEALEYYERALRLAADFENS 473
A L +LSL L VY +G ++ A++ Y RA+ L F ++
Sbjct: 246 AAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDA 295
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 53.1 bits (126), Expect = 5e-07
Identities = 47/176 (26%), Positives = 79/176 (44%), Gaps = 22/176 (12%)
Query: 253 VFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ--------MIQIKE 304
VF A+ G +++A+ L KA+Q P++ L H+ L + ++ Q E
Sbjct: 218 VFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLE 277
Query: 305 ATKGQPRGQNREKLD----KMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360
K QP + L +++ AI F+ A+++K F A+ L + Y E GN A
Sbjct: 278 LNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAAT 337
Query: 361 ENFQKLLCMKPVVEETMQ---DIHFHYGRFQEFQKK-------SDVNAIIHYLKAI 406
E+FQK L + +T+Q + +H+G QE K N + Y+K +
Sbjct: 338 ESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGL 393
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 50.4 bits (119), Expect = 3e-06
Identities = 44/164 (26%), Positives = 75/164 (45%), Gaps = 22/164 (13%)
Query: 265 GSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ--------MIQIKEATKGQPRGQNRE 316
G +++A+ L KA+Q P++ L H+ L + ++ Q E K QP +
Sbjct: 177 GRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYK 236
Query: 317 KLD----KMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPV 372
L +++ AI F+ A+++K F A+ L + Y E GN A E+FQK L +
Sbjct: 237 GLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQN 296
Query: 373 VEETMQ---DIHFHYGRFQEFQKK-------SDVNAIIHYLKAI 406
+T+Q + +H+G QE K N + Y+K +
Sbjct: 297 HVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGL 340
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/264 (18%), Positives = 113/264 (42%), Gaps = 25/264 (9%)
Query: 207 RQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGS 266
++A++L+P + L L+ + ++ E +++++ + A +
Sbjct: 430 QRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQER 489
Query: 267 VDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAI 326
+A E+ + ++ P S LH+ G+ G P A+
Sbjct: 490 FKEAEEIYQTGIKNCPDSSDLHNNYGVFL---------VDTGLPE------------KAV 528
Query: 327 FHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLL--CMKPVVEETMQDIHFHY 384
H++ A++ P+ VA ++L R+Y G + AEE +++ L K + + ++++
Sbjct: 529 AHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNT 588
Query: 385 GRFQE-FQKKSDVNAIIHYLKAIKIEQAS-LTRDKSINSLKKLVLRKLRRKALDLESLSL 442
GR++E Q + A+ + +++ A L +K+ + + LE L
Sbjct: 589 GRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRL 648
Query: 443 LGFVYKLEGNMNEALEYYERALRL 466
L +Y + N ++AL+ ++AL+L
Sbjct: 649 LSAIYSKQENHDKALDAIDKALQL 672
Score = 47.4 bits (111), Expect = 3e-05
Identities = 89/427 (20%), Positives = 163/427 (38%), Gaps = 77/427 (18%)
Query: 60 YVKHLK--GQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYY----------- 106
Y LK G+N+EA+ + A L N+ +L A MYY
Sbjct: 381 YANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHN 440
Query: 107 ----HMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKA 162
++G L ++Q +K E L + +Y E D A L + ++ A+
Sbjct: 441 RALFNLGNLLKSQ---EKKEEAITLLKDSIKYGPEFA--DAYSSLASLLAEQERFKEAEE 495
Query: 163 CFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVL 222
++ ++ P++ + Y G L ++ +QA++L+P + V
Sbjct: 496 IYQTGIKNCPDSSDLHNNY--------GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVN 547
Query: 223 LALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETP 282
L + G+ + E++ + AL ++ + + Y G ++AL++ ++A P
Sbjct: 548 LGRLYRSLGENSMAEEWYKRAL-QVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQP 606
Query: 283 TSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVA 342
+ L + AQ++ + TK EK+ I S E+ E
Sbjct: 607 SQRELRLAL-----AQVLAVMGQTK------EAEKMTNHIVS---------EETGCLECY 646
Query: 343 HLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHY 402
L L+ +Y + NH KA + K L +KP + + ++ F G Q D A Y
Sbjct: 647 RL-LSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLD-KAFESY 704
Query: 403 LKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYER 462
A++ L D++ ++ +G + ++G A YYER
Sbjct: 705 RVAVQ-----LNPDQA-------------------QAWMNMGGIQHIKGKYVSARAYYER 740
Query: 463 ALRLAAD 469
AL+L D
Sbjct: 741 ALQLVPD 747
Score = 42.7 bits (99), Expect = 7e-04
Identities = 47/191 (24%), Positives = 82/191 (42%), Gaps = 22/191 (11%)
Query: 207 RQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGS 266
++A L P +++ LA L GQ E EK ++ + +R + Y ++ +
Sbjct: 599 QEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQEN 658
Query: 267 VDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKG-QPRGQNREKLDKMIRSA 325
DKAL+ + KALQ P ++I TKG Q R QN LDK S
Sbjct: 659 HDKALDAIDKALQLKPKD------------PKVISELFFTKGNQLREQN--LLDKAFES- 703
Query: 326 IFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP---VVEETMQDIHF 382
+ AV+ P A +++ + G + A +++ L + P +++E + +
Sbjct: 704 ---YRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDR 760
Query: 383 HYGRFQEFQKK 393
R QE ++K
Sbjct: 761 LEKRLQEVREK 771
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 47.4 bits (111), Expect = 3e-05
Identities = 55/246 (22%), Positives = 102/246 (41%), Gaps = 39/246 (15%)
Query: 237 EKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVL---LHHQIGL 293
++ +++ A+ SS T K Y +G ++AL + K+A+Q+ P L++ +G
Sbjct: 592 DENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGE 651
Query: 294 CYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEA 353
Y +L K+ + ++ ES + K AHL ++
Sbjct: 652 AYM--------------------RLSKLPEAEHWYMES-LRSKTDHIPAHLTYGKLLALT 690
Query: 354 GNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASL 413
G +AE+ F K + + P T + + HYG+F ++ + A KA +++
Sbjct: 691 GRKSEAEKLFLKAIELDP----TKGNCYMHYGQFL-LEEARLIEAAEMAKKAAELDSTEF 745
Query: 414 -TRDKSINSLKKLVLRKLRRKALDL---------ESLSLLGFVYKLEGNMNEALEYYERA 463
+ + L++ L + K DL +L LG + L G + +A Y RA
Sbjct: 746 DVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLRA 805
Query: 464 LRLAAD 469
L+L D
Sbjct: 806 LQLKPD 811
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 47.0 bits (110), Expect = 4e-05
Identities = 44/194 (22%), Positives = 84/194 (43%), Gaps = 11/194 (5%)
Query: 104 MYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCG--GKNYERAK 161
+Y+H G+L + LD+VE R R E ++ +AL + G N + +
Sbjct: 403 VYHHRGQL---KILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQ 459
Query: 162 ACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKV 221
A + EV + P + GYA+ A L + K + + + + L PDN V
Sbjct: 460 AAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYD-----KCIDLEPDNATTYV 514
Query: 222 LLAL-KLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQE 280
L +LQ + G + I +A+ + + + ++G+++KA+++ KA+
Sbjct: 515 HKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574
Query: 281 TPTSVLLHHQIGLC 294
+ + + H LC
Sbjct: 575 AKSEMEMAHLYSLC 588
Score = 32.7 bits (73), Expect = 0.74
Identities = 48/250 (19%), Positives = 100/250 (40%), Gaps = 44/250 (17%)
Query: 225 LKLQDEGQEAEGEKYIEEALANMSSQTY-----VFRYAAKFYRRKGSVDKALELLKKALQ 279
+KL+ G Y+++ +S+Q + + A Y +G + L+ +++A+
Sbjct: 363 VKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVA 422
Query: 280 ETPTSVLLHHQIGLCYKAQMIQI-KEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPT 338
+ + L + L + + ++A G Q I++A+ FE ++K P
Sbjct: 423 DFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQ--------IQAAMKGFEEVIKKFPR 474
Query: 339 FEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNA 398
+ A+ + KA+E + K + ++P T + H G Q Q K D++
Sbjct: 475 CAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATT----YVHKGLLQ-LQWKQDLDR 529
Query: 399 IIHYL-KAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEAL 457
+ + KAI+I+ D + +G + GNM +A+
Sbjct: 530 GLELISKAIEID-----------------------NKCDF-AYETMGTIEVQRGNMEKAI 565
Query: 458 EYYERALRLA 467
+ + +A+ LA
Sbjct: 566 DMFNKAINLA 575
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 44.7 bits (104), Expect = 2e-04
Identities = 104/504 (20%), Positives = 193/504 (38%), Gaps = 89/504 (17%)
Query: 25 LSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAE---NL 81
+ +D D++P+ + V+ ++ T+ + I L Y K +G+ EE +K L+ A NL
Sbjct: 17 IELDFDQLPE-GDEVISILKQEHTQLHIWIALALEYYK--QGKTEEFVKLLEAARIDGNL 73
Query: 82 MQEEHD----------------------NQANVRSLVTWGNFAW-------MY---YHMG 109
+H+ N+ N + L+T + MY + +G
Sbjct: 74 DYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMADKIIMYDQNHLLG 133
Query: 110 RLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLE 169
R DK++ + F I G A + K+Y A A ++K L
Sbjct: 134 RACFCLLEGDKMDQADAQFH--FVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALR 191
Query: 170 VDPENP-ESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDN-GYIKVLLALKL 227
+P P E G +L+ + A L +A+ LN G + L L+L
Sbjct: 192 TNPGCPAEVRLGMGHCFVKLNKLEKAR--------LAFSRALELNSKCVGALVGLAVLEL 243
Query: 228 QDEGQEA--EGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSV 285
++ ++ G + + A S V + A + K K L A T
Sbjct: 244 NNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEA 303
Query: 286 LLHHQIGLCYK-AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHL 344
+ Q CY+ A+ ++E D+ + +++++ +F +
Sbjct: 304 M---QAESCYQLARSFHVQE------------DYDQAFQ---YYYQATQFASSSFVLPFF 345
Query: 345 DLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKK----------- 393
L +MYI G+ A + F+K+L P ETM+ + Y ++ +K+
Sbjct: 346 GLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVT 405
Query: 394 ----SDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKL 449
DV A I + +EQ + S +L++ + + E L+ +G ++
Sbjct: 406 EQYPDDVEAWIELAQI--LEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFR 463
Query: 450 EGNMNEALEYYERAL-RLAADFEN 472
GN+ EA +Y+ +L R A+ E+
Sbjct: 464 LGNLGEAKKYFLASLDRAKAEAEH 487
>gi|239741018 PREDICTED: hypothetical protein XP_002342056 [Homo
sapiens]
Length = 566
Score = 38.5 bits (88), Expect = 0.014
Identities = 57/217 (26%), Positives = 92/217 (42%), Gaps = 29/217 (13%)
Query: 164 FEKVLEVDPENPESSAGYAISAYRLD-----------GFKLATKNHKPF--SLLPLRQAV 210
F VL +P N ++ G A+ LD KL P SL P QA+
Sbjct: 201 FNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTVVPELRSLKPEAQAL 260
Query: 211 RLNPDNGYIKVLLALKLQDEG-----QEAEGEKYIEEALANMSS-QTYVFRYAAKFYRRK 264
+ + LL+ +L D G ++ +G + EAL + S Q + A +
Sbjct: 261 ITQGLYSHCRALLS-QLPDTGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQ 319
Query: 265 GSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEA-TKGQPRG-QNREKLDKMI 322
GS ++A L+KAL PTS ++GL +Q+K+ G R Q+ ++D
Sbjct: 320 GSYEEAGTHLEKALHRAPTSEAARARLGL------LQLKKGDVPGAARDLQSLAEVDAPD 373
Query: 323 RSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKA 359
S + H A E++ + A + A ++AG R+A
Sbjct: 374 LSCLLHLLEASERQSLAQAAAQE-AGTLLDAGQPRQA 409
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 38.1 bits (87), Expect = 0.018
Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 12/134 (8%)
Query: 345 DLARMYIEAGNHRKAEENFQK-LLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYL 403
D A+ Y GN +A + Q+ L+C E+ + H F + Q ++ ++ L
Sbjct: 915 DQAKAYRGLGNGHRAMGSLQQALVCF----EKRLVVAHELGEAFNKAQAYGELGSLHSQL 970
Query: 404 KAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERA 463
EQA ++ +N + R ++ +AL+ ++ LG VY+ G + AL+Y++
Sbjct: 971 G--NYEQAISCLERQLN-----IARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLD 1023
Query: 464 LRLAADFENSVRQG 477
L++A + N QG
Sbjct: 1024 LQIAEETNNPTCQG 1037
Score = 32.0 bits (71), Expect = 1.3
Identities = 18/52 (34%), Positives = 28/52 (53%)
Query: 426 VLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQG 477
+ R+LR + +LS LG + G +A YYE+ LRLA D ++ +G
Sbjct: 583 IARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEG 634
Score = 32.0 bits (71), Expect = 1.3
Identities = 14/34 (41%), Positives = 21/34 (61%)
Query: 443 LGFVYKLEGNMNEALEYYERALRLAADFENSVRQ 476
LG+ + GN EA++YYE+ L LA D + + Q
Sbjct: 640 LGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQ 673
Score = 29.3 bits (64), Expect = 8.2
Identities = 17/90 (18%), Positives = 45/90 (50%), Gaps = 7/90 (7%)
Query: 388 QEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVY 447
+E + S++ + HY + + + S ++ + ++L KA+++ + + LG
Sbjct: 392 EEARAYSNLGSAYHYRR-------NFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAA 444
Query: 448 KLEGNMNEALEYYERALRLAADFENSVRQG 477
+ ++ A +Y+E+ L +A D ++ +G
Sbjct: 445 RCMQDLERAKQYHEQQLGIAEDLKDRAAEG 474
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 37.4 bits (85), Expect = 0.030
Identities = 44/192 (22%), Positives = 80/192 (41%), Gaps = 24/192 (12%)
Query: 9 QVKDSLEQLRCHFTWELSIDDDEMPDLENRVLD-QIEFLDTKYSVGIHNLLAYVKHLKGQ 67
QVK + E+L+ D M DLEN D + + ++ + G+ + ++
Sbjct: 13 QVKQNAEELQ-----------DFMRDLENWEKDIKQKDMELRRQNGVPE--ENLPPIRNG 59
Query: 68 NEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKK 127
N K K E+ + +N N + ++ AW + R+ + LDK ++ +
Sbjct: 60 NFRKKKKGKAKESSKKTREENTKN--RIKSYDYEAWAKLDVDRILDE---LDKDDSTHES 114
Query: 128 LSNPFRYRMECPEIDCEEGWALLKCGGK-----NYERAKACFEKVLEVDPENPESSAGYA 182
LS + +D ++ L + G K Y+ A C+ K ++ DP NP A
Sbjct: 115 LSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRA 174
Query: 183 ISAYRLDGFKLA 194
+ +RL F +A
Sbjct: 175 SAYFRLKKFAVA 186
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 37.4 bits (85), Expect = 0.030
Identities = 44/192 (22%), Positives = 80/192 (41%), Gaps = 24/192 (12%)
Query: 9 QVKDSLEQLRCHFTWELSIDDDEMPDLENRVLD-QIEFLDTKYSVGIHNLLAYVKHLKGQ 67
QVK + E+L+ D M DLEN D + + ++ + G+ + ++
Sbjct: 13 QVKQNAEELQ-----------DFMRDLENWEKDIKQKDMELRRQNGVPE--ENLPPIRNG 59
Query: 68 NEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKK 127
N K K E+ + +N N + ++ AW + R+ + LDK ++ +
Sbjct: 60 NFRKKKKGKAKESSKKTREENTKN--RIKSYDYEAWAKLDVDRILDE---LDKDDSTHES 114
Query: 128 LSNPFRYRMECPEIDCEEGWALLKCGGK-----NYERAKACFEKVLEVDPENPESSAGYA 182
LS + +D ++ L + G K Y+ A C+ K ++ DP NP A
Sbjct: 115 LSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRA 174
Query: 183 ISAYRLDGFKLA 194
+ +RL F +A
Sbjct: 175 SAYFRLKKFAVA 186
>gi|225735631 mesoderm induction early response 1 isoform g [Homo
sapiens]
Length = 470
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 2 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLA-- 59
S DDH+ S + L F E +++++EM + E +IE L + + IH LL+
Sbjct: 31 SATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLY 90
Query: 60 -YVKHLKGQNEEALKSLKEAENLMQEEHDNQAN 91
Y ++ E+ + +E E E+ DN N
Sbjct: 91 GYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDN 123
>gi|225735615 mesoderm induction early response 1 isoform a [Homo
sapiens]
Length = 529
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 2 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLA-- 59
S DDH+ S + L F E +++++EM + E +IE L + + IH LL+
Sbjct: 31 SATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLY 90
Query: 60 -YVKHLKGQNEEALKSLKEAENLMQEEHDNQAN 91
Y ++ E+ + +E E E+ DN N
Sbjct: 91 GYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDN 123
>gi|118130872 mesoderm induction early response 1 isoform f [Homo
sapiens]
Length = 433
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 2 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLA-- 59
S DDH+ S + L F E +++++EM + E +IE L + + IH LL+
Sbjct: 14 SATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLY 73
Query: 60 -YVKHLKGQNEEALKSLKEAENLMQEEHDNQAN 91
Y ++ E+ + +E E E+ DN N
Sbjct: 74 GYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDN 106
>gi|225735612 mesoderm induction early response 1 isoform e [Homo
sapiens]
Length = 486
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 2 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLA-- 59
S DDH+ S + L F E +++++EM + E +IE L + + IH LL+
Sbjct: 67 SATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLY 126
Query: 60 -YVKHLKGQNEEALKSLKEAENLMQEEHDNQAN 91
Y ++ E+ + +E E E+ DN N
Sbjct: 127 GYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDN 159
>gi|225735610 mesoderm induction early response 1 isoform d [Homo
sapiens]
Length = 450
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 2 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLA-- 59
S DDH+ S + L F E +++++EM + E +IE L + + IH LL+
Sbjct: 31 SATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLY 90
Query: 60 -YVKHLKGQNEEALKSLKEAENLMQEEHDNQAN 91
Y ++ E+ + +E E E+ DN N
Sbjct: 91 GYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDN 123
>gi|118130815 mesoderm induction early response 1 isoform c [Homo
sapiens]
Length = 512
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 2 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLA-- 59
S DDH+ S + L F E +++++EM + E +IE L + + IH LL+
Sbjct: 14 SATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLY 73
Query: 60 -YVKHLKGQNEEALKSLKEAENLMQEEHDNQAN 91
Y ++ E+ + +E E E+ DN N
Sbjct: 74 GYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDN 106
>gi|225735607 mesoderm induction early response 1 isoform b [Homo
sapiens]
Length = 565
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 2 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLA-- 59
S DDH+ S + L F E +++++EM + E +IE L + + IH LL+
Sbjct: 67 SATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLY 126
Query: 60 -YVKHLKGQNEEALKSLKEAENLMQEEHDNQAN 91
Y ++ E+ + +E E E+ DN N
Sbjct: 127 GYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDN 159
>gi|225735605 mesoderm induction early response 1 isoform a [Homo
sapiens]
Length = 529
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 2 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLA-- 59
S DDH+ S + L F E +++++EM + E +IE L + + IH LL+
Sbjct: 31 SATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLY 90
Query: 60 -YVKHLKGQNEEALKSLKEAENLMQEEHDNQAN 91
Y ++ E+ + +E E E+ DN N
Sbjct: 91 GYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDN 123
>gi|118402578 anaphase-promoting complex, subunit 6 [Homo sapiens]
Length = 620
Score = 37.4 bits (85), Expect = 0.030
Identities = 41/151 (27%), Positives = 65/151 (43%), Gaps = 21/151 (13%)
Query: 343 HLDLARMYIEAG---NHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAI 399
HL + + +E G N + AE F + L + P M ++ FQ + K+
Sbjct: 368 HLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVV--AFQNGEWKTAEKWF 425
Query: 400 IHYLKAIKIEQASLTRDKSINSLKKL--VLRKLRRKALDLE--------------SLSLL 443
+ L+ IK +T DK L L V RKL++ A L+ + S +
Sbjct: 426 LDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAI 485
Query: 444 GFVYKLEGNMNEALEYYERALRLAADFENSV 474
G+++ L GN A++Y+ AL L D SV
Sbjct: 486 GYIHSLMGNFENAVDYFHTALGLRRDDTFSV 516
>gi|118402580 anaphase-promoting complex, subunit 6 [Homo sapiens]
Length = 620
Score = 37.4 bits (85), Expect = 0.030
Identities = 41/151 (27%), Positives = 65/151 (43%), Gaps = 21/151 (13%)
Query: 343 HLDLARMYIEAG---NHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAI 399
HL + + +E G N + AE F + L + P M ++ FQ + K+
Sbjct: 368 HLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVV--AFQNGEWKTAEKWF 425
Query: 400 IHYLKAIKIEQASLTRDKSINSLKKL--VLRKLRRKALDLE--------------SLSLL 443
+ L+ IK +T DK L L V RKL++ A L+ + S +
Sbjct: 426 LDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAI 485
Query: 444 GFVYKLEGNMNEALEYYERALRLAADFENSV 474
G+++ L GN A++Y+ AL L D SV
Sbjct: 486 GYIHSLMGNFENAVDYFHTALGLRRDDTFSV 516
>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
sapiens]
Length = 864
Score = 37.0 bits (84), Expect = 0.039
Identities = 77/360 (21%), Positives = 137/360 (38%), Gaps = 70/360 (19%)
Query: 11 KDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLD---TKYSVGIHNLLAYVKHLKGQ 67
KD+L+ LR +LS+ +M DLE + + L T+ + I +AY HL
Sbjct: 111 KDNLQILR-----DLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAY--HLLKD 163
Query: 68 NEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKK 127
+ ALK L+E Q + + + + Y + EA + +E+I
Sbjct: 164 YDMALKLLEEFRQTQQVPPNK-------IDYEYSELILYQNQVMREADLLQESLEHI--- 213
Query: 128 LSNPFRYRMECPEIDCEE--GWALLKCGGKNYERAKACFEKVLEVDPEN------PESSA 179
+ C ++ EE G LLK G + A F+ +++ + EN E +
Sbjct: 214 ---EMYEKQICDKLLVEEIKGEILLKLG--RLKEASEVFKNLIDRNAENWCYYEGLEKAL 268
Query: 180 GYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVL--------------LAL 225
+ RL ++ +K H P ++ P R + L P + +++ L
Sbjct: 269 QISTLEERLQIYEEISKQH-PKAITPRRLPLTLVPGERFRELMDKFLRVNFSKGCPPLFT 327
Query: 226 KLQDEGQEAEGEKYIEEALANMSSQT---------------------YVFRYAAKFYRRK 264
L+ E I+E + N + +V + A+ + +
Sbjct: 328 TLKSLYYNTEKVSIIQELVTNYEASLKTCDFFSPYENGEKEPPTTLLWVQYFLAQHFDKL 387
Query: 265 GSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRS 324
G AL+ + A+ TPT + L + YK + +KEA K Q+ + D+ I S
Sbjct: 388 GQYSLALDYINAAIASTPTLIELFYMKAKIYK-HIGNLKEAAKWMDEAQSLDTADRFINS 446
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 36.6 bits (83), Expect = 0.052
Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 11/145 (7%)
Query: 304 EATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENF 363
EA + + G + K++ +A+ + A+E P V + A Y + GN+ A ++
Sbjct: 90 EAERLKTEGNEQMKVENF-EAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDC 148
Query: 364 QKLLCMKPVVEETMQDIHFHYGR--FQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS 421
++ +C+ P + YGR V A+ +Y KA++++ + T KS
Sbjct: 149 ERAICIDPAYSKA-------YGRMGLALSSLNKHVEAVAYYKKALELDPDNETY-KSNLK 200
Query: 422 LKKLVLRKLRRKALDLESLSLLGFV 446
+ +L LR+ + S + G +
Sbjct: 201 IAELKLREAPSPTGGVGSFDIAGLL 225
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,585,235
Number of Sequences: 37866
Number of extensions: 704333
Number of successful extensions: 2576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 2388
Number of HSP's gapped (non-prelim): 216
length of query: 478
length of database: 18,247,518
effective HSP length: 106
effective length of query: 372
effective length of database: 14,233,722
effective search space: 5294944584
effective search space used: 5294944584
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.