Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 116517292
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116517292 cut-like 2 [Homo sapiens]
(1486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116517292 cut-like 2 [Homo sapiens] 2942 0.0
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 1050 0.0
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 348 2e-95
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens] 348 2e-95
gi|122937424 one cut homeobox 3 [Homo sapiens] 82 5e-15
gi|24307887 one cut homeobox 1 [Homo sapiens] 77 9e-14
gi|119220564 one cut domain, family member 2 [Homo sapiens] 69 4e-11
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 64 8e-10
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 64 8e-10
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 64 8e-10
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 64 8e-10
gi|21735548 centrosomal protein 2 [Homo sapiens] 62 4e-09
gi|54860079 nadrin isoform 1 [Homo sapiens] 62 5e-09
gi|81295809 pericentrin [Homo sapiens] 60 2e-08
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 60 2e-08
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 59 3e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 5e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 59 5e-08
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 59 5e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 58 8e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 58 8e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 58 8e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 58 8e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 57 1e-07
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 57 2e-07
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 57 2e-07
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 56 3e-07
gi|139394646 iroquois homeobox protein 5 [Homo sapiens] 55 5e-07
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 54 9e-07
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 54 1e-06
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 2942 bits (7627), Expect = 0.0
Identities = 1486/1486 (100%), Positives = 1486/1486 (100%)
Query: 1 MAANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEI 60
MAANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEI
Sbjct: 1 MAANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEI 60
Query: 61 REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPS 120
REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPS
Sbjct: 61 REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPS 120
Query: 121 FDPSGQPRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQR 180
FDPSGQPRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQR
Sbjct: 121 FDPSGQPRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQR 180
Query: 181 NEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVG 240
NEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVG
Sbjct: 181 NEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVG 240
Query: 241 LIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLE 300
LIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLE
Sbjct: 241 LIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLE 300
Query: 301 AALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQS 360
AALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQS
Sbjct: 301 AALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQS 360
Query: 361 DYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPE 420
DYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPE
Sbjct: 361 DYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPE 420
Query: 421 EDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSP 480
EDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSP
Sbjct: 421 EDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSP 480
Query: 481 FPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGGG 540
FPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGGG
Sbjct: 481 FPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGGG 540
Query: 541 GGAAGPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRK 600
GGAAGPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRK
Sbjct: 541 GGAAGPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRK 600
Query: 601 LTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQRGSITPRIRTPETGSDDAIKSILEQAKK 660
LTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQRGSITPRIRTPETGSDDAIKSILEQAKK
Sbjct: 601 LTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQRGSITPRIRTPETGSDDAIKSILEQAKK 660
Query: 661 EIESQKGGEPKTSVAPLSIANGTTPASTSEDAIKSILEQARREMQAQQQALLEMEVAPRG 720
EIESQKGGEPKTSVAPLSIANGTTPASTSEDAIKSILEQARREMQAQQQALLEMEVAPRG
Sbjct: 661 EIESQKGGEPKTSVAPLSIANGTTPASTSEDAIKSILEQARREMQAQQQALLEMEVAPRG 720
Query: 721 RSVPPSPPERPSLATASQNGAPALVKQEEGSGGPAQAPLPVLSPAAFVQSIIRKVKSEIG 780
RSVPPSPPERPSLATASQNGAPALVKQEEGSGGPAQAPLPVLSPAAFVQSIIRKVKSEIG
Sbjct: 721 RSVPPSPPERPSLATASQNGAPALVKQEEGSGGPAQAPLPVLSPAAFVQSIIRKVKSEIG 780
Query: 781 DAGYFDHHWASDRGLLSRPYASVSPSLSSSSSSGYSGQPNGRAWPRGDEAPVPPEDEAAA 840
DAGYFDHHWASDRGLLSRPYASVSPSLSSSSSSGYSGQPNGRAWPRGDEAPVPPEDEAAA
Sbjct: 781 DAGYFDHHWASDRGLLSRPYASVSPSLSSSSSSGYSGQPNGRAWPRGDEAPVPPEDEAAA 840
Query: 841 GAEDEPPRTGELKAEGATAEAGARLPYYPAYVPRTLKPTVPPLTPEQYELYMYREVDTLE 900
GAEDEPPRTGELKAEGATAEAGARLPYYPAYVPRTLKPTVPPLTPEQYELYMYREVDTLE
Sbjct: 841 GAEDEPPRTGELKAEGATAEAGARLPYYPAYVPRTLKPTVPPLTPEQYELYMYREVDTLE 900
Query: 901 LTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLS 960
LTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLS
Sbjct: 901 LTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLS 960
Query: 961 DQLGQAVGQQPGASQASPTEPRSSPSPPPSPTEPEKSSQEPLSLSLESSKENQQPEGRSS 1020
DQLGQAVGQQPGASQASPTEPRSSPSPPPSPTEPEKSSQEPLSLSLESSKENQQPEGRSS
Sbjct: 961 DQLGQAVGQQPGASQASPTEPRSSPSPPPSPTEPEKSSQEPLSLSLESSKENQQPEGRSS 1020
Query: 1021 SSLSGKMYSGSQAPGGIQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQG 1080
SSLSGKMYSGSQAPGGIQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQG
Sbjct: 1021 SSLSGKMYSGSQAPGGIQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQG 1080
Query: 1081 SVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLIST 1140
SVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLIST
Sbjct: 1081 SVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLIST 1140
Query: 1141 GSDSESPATRSECPSPCLQPQDLSLLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIEL 1200
GSDSESPATRSECPSPCLQPQDLSLLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIEL
Sbjct: 1141 GSDSESPATRSECPSPCLQPQDLSLLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIEL 1200
Query: 1201 LSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQS 1260
LSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQS
Sbjct: 1201 LSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQS 1260
Query: 1261 PDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGSQPQDSGE 1320
PDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGSQPQDSGE
Sbjct: 1261 PDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGSQPQDSGE 1320
Query: 1321 LDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHPDPLSF 1380
LDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHPDPLSF
Sbjct: 1321 LDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHPDPLSF 1380
Query: 1381 KSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTAD 1440
KSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTAD
Sbjct: 1381 KSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTAD 1440
Query: 1441 MAGALHPSAKVNPNLQRRHEKMANLNNIIYRVERAANREEALEWEF 1486
MAGALHPSAKVNPNLQRRHEKMANLNNIIYRVERAANREEALEWEF
Sbjct: 1441 MAGALHPSAKVNPNLQRRHEKMANLNNIIYRVERAANREEALEWEF 1486
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 1050 bits (2714), Expect = 0.0
Identities = 690/1579 (43%), Positives = 916/1579 (58%), Gaps = 192/1579 (12%)
Query: 19 RLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQAEVVAL 78
RL++EL++ A+ L+ RQ+ESE S K LIE REFKKN PE++R+ VAP+LKSFQ E+ AL
Sbjct: 8 RLKRELDATATVLANRQDESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQGEIDAL 67
Query: 79 SKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHTSWKRN 138
SKRS+EAEAAFL+VYK+LI+ PDPVP + + L ++Q D + ++ T + N
Sbjct: 68 SKRSKEAEAAFLNVYKRLIDVPDPVPALDLGQQLQLKVQR-LHDIETENQKLRETLEEYN 126
Query: 139 PELLSPKEQREGTSPAGPTLTEGSRLPGIPGK--ALLTETLLQRNEAEKQKGLQEVQITL 196
E K Q + E + + AL E LQ + AEK++ LQE Q++
Sbjct: 127 KEFAEVKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMST 186
Query: 197 AARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAA 256
++L EAE K++ L +AL+ T+ EL +L+ KYDEE +KADE+ +IMT+LE+ANQRAE A
Sbjct: 187 TSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVA 246
Query: 257 QREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDREILRLLKD 316
QRE E+LREQL+S N S++LA + P ++ + + LE LA+K+REI +L++D
Sbjct: 247 QREAETLREQLSSANHSLQLASQIQKAPDVEQA-IEVLTRSSLEVELAAKEREIAQLVED 305
Query: 317 VQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEIKTELSILKAMK 376
VQ LQ+SL +L E SA+QI+ LE+QL+AK+ +++LEEKL+ Q+DYEE+K EL+ILK+M+
Sbjct: 306 VQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSME 365
Query: 377 LASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPEEDPSEDDSIKDSLGTE 436
A S + Q AKP + LL+ K ++ L + S D +
Sbjct: 366 FAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGS 425
Query: 437 QSYPSPQQLPPPPGPE-------DPLSPSP------GQPLLGPSLGPDGTRTFSLSPFPS 483
P P QLP PG + SP+ L PSL T F+L+ S
Sbjct: 426 LPAPPPSQLPRNPGEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALN---S 482
Query: 484 LASGERLMMPPAAFKGEAGGL-LVFPPAFYGAKPPTAPATPAPGPEPLG-GPEPADGGGG 541
L + + + EAG ++F Y ++ + P+ G P P+
Sbjct: 483 LLQRQLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQSPDVNGMAPSPSQSESA 542
Query: 542 GAAGPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKL 601
G+ G E++DTAEIA QVKEQL+KHNIGQR+FGHYVLGLSQGSVSEILARPKPW KL
Sbjct: 543 GSVSEG---EEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKL 599
Query: 602 TVKGKEPFIKMKQFLSDEQNVLALRTIQVRQR----------------------GSITPR 639
TV+GKEPF KMKQFLSDEQN+LALR+IQ RQR G+IT R
Sbjct: 600 TVRGKEPFHKMKQFLSDEQNILALRSIQGRQRENPGQSLNRLFQEVPKRRNGSEGNITTR 659
Query: 640 IRTPETGSDDAIKSILEQAKKEIESQKGGEPKTSVAPLSIANGTTPASTSEDAIKSILEQ 699
IR ETGSD+AIKSILEQAK+E++ QK EP A S A+G+ S+DAI+SIL+Q
Sbjct: 660 IRASETGSDEAIKSILEQAKRELQVQKTAEP----AQPSSASGS---GNSDDAIRSILQQ 712
Query: 700 ARREMQAQQQAL---------------------LEMEVAPRGRSVPP------SPPERPS 732
ARREM+AQQ AL L P S PP P P
Sbjct: 713 ARREMEAQQAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYPPLAISLKKPSAAPE 772
Query: 733 LATASQNGAPALVKQEEGSGGPAQAPLPVLSPAAFVQSIIRKVKSEIGDAGYFDHHWASD 792
++ PAL K+ + + G L A Q ++R+VK+E+G +G + HW S
Sbjct: 773 AGASALPNPPALKKEAQDAPG-----LDPQGAADCAQGVLRQVKNEVGRSGAWKDHWWSA 827
Query: 793 RGLLSRPYASVSPSLSSSSSSGY---SGQPNGRAWPRGDEAPVPPEDEAA-----AGAED 844
R AS + + + G SG G + PR + + + + AE
Sbjct: 828 VQPERRNAASSEEAKAEETGGGKEKGSGGSGGGSQPRAERSQLQGPSSSEYWKEWPSAES 887
Query: 845 EPPRTGELKAEGATAEA---GARLPYYPAY-VPRTLKPTVPPLTPEQYELYMYREVDTLE 900
++ EL GA+ + LP P + + KP+VPPLTPEQYE+YMY+EVDT+E
Sbjct: 888 PYSQSSELSLTGASRSETPQNSPLPSSPIVPMSKPTKPSVPPLTPEQYEVYMYQEVDTIE 947
Query: 901 LTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLS 960
LTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWL+
Sbjct: 948 LTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLN 1007
Query: 961 DQLGQAV----GQQPG---------------ASQASPTEPRSSPSPPPSPTEPEKSSQEP 1001
+LGQ V GQQ G +S + P++S S P+P P SS+
Sbjct: 1008 GELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESV 1067
Query: 1002 LSLS---------LESSKENQQPEGR----SSSSLSGKMYSGSQAPGGIQEIVAMSPELD 1048
SL+ +E+SK+++ PE S S + + + IQE+VAMSPELD
Sbjct: 1068 KSLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTPLPLSGHSALSIQELVAMSPELD 1127
Query: 1049 TYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQL 1108
TY ITKRVKEVLTDNNLGQRLFGE+ILGLTQGSVSDLL+RPKPWHKLSLKGREPFVRMQL
Sbjct: 1128 TYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQL 1187
Query: 1109 WLNDPHNVEKLRDMKKLEKKAYLKRRYGLISTGSDSESPATRSE-CPSPCLQPQDLSLLQ 1167
WLNDP+NVEKL DMK++EKKAY+KRR+ +S E P+ +E QPQ Q
Sbjct: 1188 WLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQH----Q 1243
Query: 1168 IKKPRVVLAPEEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREM 1227
+KKPRVVLAPEEKEAL++AYQ +PYPS +TIE L+ QLNLKT+TVINWFHNYRSR+RRE+
Sbjct: 1244 LKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRREL 1303
Query: 1228 LVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTP 1287
+E Q +G G + P+ +S + + + +E EGP +
Sbjct: 1304 FIEEIQ-------AGSQG---QAGASDSPSARSGRAAPSSEGDSCDGVEATEGP---GSA 1350
Query: 1288 LTTQDKAQVRIKQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPG 1347
T + K+Q ++E++ AE+ ++P SG GP D ++G P PG
Sbjct: 1351 DTEEPKSQGEAEREEVPRPAEQ---TEPPPSGT----PGPDDARDDD---HEGGPVEGPG 1400
Query: 1348 PLLPGGSTPDCPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLM 1407
PL P P S + + ++ + E + S +AA G
Sbjct: 1401 PL-------------------------PSPAS--ATATAAPAAPEDAATSAAAAPGEGPA 1433
Query: 1408 MSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMAGALHPSAKVNPNLQRRHEKMANLNN 1467
S P S++ S +P P+ + S + AGA ++ NP R +K ANLN+
Sbjct: 1434 APSSAPPPSNSSSSSAP--RRPSSLQSLFGLPEAAGA--RDSRDNP---LRKKKAANLNS 1486
Query: 1468 IIYRVERAANREEALEWEF 1486
II+R+E+AA+REE +EWEF
Sbjct: 1487 IIHRLEKAASREEPIEWEF 1505
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 348 bits (894), Expect = 2e-95
Identities = 198/401 (49%), Positives = 276/401 (68%), Gaps = 6/401 (1%)
Query: 1 MAANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEI 60
MAANVGSMFQYWKRFDL++LQ+EL++ A+ L+ RQ+ESE S K LIE REFKKN PE++
Sbjct: 1 MAANVGSMFQYWKRFDLQQLQRELDATATVLANRQDESEQSRKRLIEQSREFKKNTPEDL 60
Query: 61 REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPS 120
R+ VAP+LKSFQ E+ ALSKRS+EAEAAFL+VYK+LI+ PDPVP + + L ++Q
Sbjct: 61 RKQVAPLLKSFQGEIDALSKRSKEAEAAFLNVYKRLIDVPDPVPALDLGQQLQLKVQ-RL 119
Query: 121 FDPSGQPRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGK--ALLTETLL 178
D + ++ T + N E K Q + E + + AL E L
Sbjct: 120 HDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKL 179
Query: 179 QRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADE 238
Q + AEK++ LQE Q++ ++L EAE K++ L +AL+ T+ EL +L+ KYDEE +KADE
Sbjct: 180 QNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADE 239
Query: 239 VGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPR 298
+ +IMT+LE+ANQRAE AQRE E+LREQL+S N S++LA + P V + +
Sbjct: 240 IEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPD---VAIEVLTRSS 296
Query: 299 LEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQA 358
LE LA+K+REI +L++DVQ LQ+SL +L E SA+QI+ LE+QL+AK+ +++LEEKL+
Sbjct: 297 LEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKG 356
Query: 359 QSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAK 399
Q+DYEE+K EL+ILK+M+ A S + Q AKP + LL+ K
Sbjct: 357 QADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEK 397
>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
Length = 678
Score = 348 bits (894), Expect = 2e-95
Identities = 197/401 (49%), Positives = 277/401 (69%), Gaps = 4/401 (0%)
Query: 1 MAANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEI 60
MAANVGSMFQYWKRFDL++LQ+EL++ A+ L+ RQ+ESE S K LIE REFKKN PE++
Sbjct: 1 MAANVGSMFQYWKRFDLQQLQRELDATATVLANRQDESEQSRKRLIEQSREFKKNTPEDL 60
Query: 61 REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPS 120
R+ VAP+LKSFQ E+ ALSKRS+EAEAAFL+VYK+LI+ PDPVP + + L ++Q
Sbjct: 61 RKQVAPLLKSFQGEIDALSKRSKEAEAAFLNVYKRLIDVPDPVPALDLGQQLQLKVQ-RL 119
Query: 121 FDPSGQPRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGK--ALLTETLL 178
D + ++ T + N E K Q + E + + AL E L
Sbjct: 120 HDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKL 179
Query: 179 QRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADE 238
Q + AEK++ LQE Q++ ++L EAE K++ L +AL+ T+ EL +L+ KYDEE +KADE
Sbjct: 180 QNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADE 239
Query: 239 VGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPR 298
+ +IMT+LE+ANQRAE AQRE E+LREQL+S N S++LA + P ++ + +
Sbjct: 240 IEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQA-IEVLTRSS 298
Query: 299 LEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQA 358
LE LA+K+REI +L++DVQ LQ+SL +L E SA+QI+ LE+QL+AK+ +++LEEKL+
Sbjct: 299 LEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKG 358
Query: 359 QSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAK 399
Q+DYEE+K EL+ILK+M+ A S + Q AKP + LL+ K
Sbjct: 359 QADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEK 399
>gi|122937424 one cut homeobox 3 [Homo sapiens]
Length = 494
Score = 81.6 bits (200), Expect = 5e-15
Identities = 78/296 (26%), Positives = 116/296 (39%), Gaps = 54/296 (18%)
Query: 971 PGASQASPTEPRSSPSPPPSPTEPEKS----SQEPLSLSLESSKENQQPEGRSSSSLSGK 1026
P A+ P PP+ EP + +++ L+ L G S S +G
Sbjct: 224 PLAAYGPPGHLAGDKLLPPAAFEPHAALLGRAEDALARGLPGGGGGTGSGGAGSGSAAGL 283
Query: 1027 M--------------YSGSQAPGGI---QEIVAMSPELDTYSITKRVKEVLTDNNLGQRL 1069
+ + G PGG A + E++T + +R+ L ++ Q +
Sbjct: 284 LAPLGGLAAAGAHGPHGGGGGPGGSGGGPSAGAAAEEINTKEVAQRITAELKRYSIPQAI 343
Query: 1070 FGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKA 1129
F + IL +QG++SDLL PKPW KL GRE F RM WL +P + + M L A
Sbjct: 344 FAQRILCRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEP----EFQRMSALRLAA 398
Query: 1130 YLKRRYGLISTGSDSESPATRSECPSPCLQPQDLSLLQIKKPRVVLAPEEKEALRKAYQL 1189
C + Q LQ KK R+V ++ L ++
Sbjct: 399 -----------------------CKRKEQEQQKERALQPKKQRLVFTDLQRRTLIAIFKE 435
Query: 1190 EPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPG 1245
PS++ +S QL L+ NTV N+F N R R +EP P G G
Sbjct: 436 NKRPSKEMQVTISQQLGLELNTVSNFFMNARRRCMNRW-----AEEPSTAPGGPAG 486
Score = 79.7 bits (195), Expect = 2e-14
Identities = 69/217 (31%), Positives = 101/217 (46%), Gaps = 38/217 (17%)
Query: 440 PSPQQLPPP-PGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSPFPSLASGERLMMPPAAFK 498
P P LPP G P P P PL + GP P +G++L+ PPAAF+
Sbjct: 201 PLPNALPPALHGAPQPPPPPPPPPLA--AYGP-----------PGHLAGDKLL-PPAAFE 246
Query: 499 GEAGGLLVFPPAFYGAKPPTAPATPAPGP---------EPLGGPEPAD-----GGGGGAA 544
A L A P T + G PLGG A GGGGG
Sbjct: 247 PHAALLGRAEDALARGLPGGGGGTGSGGAGSGSAAGLLAPLGGLAAAGAHGPHGGGGGPG 306
Query: 545 GPG------AEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPW 598
G G A E+++T E+A ++ +L +++I Q +F +L SQG++S++L PKPW
Sbjct: 307 GSGGGPSAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPW 366
Query: 599 RKLTVKGKEPFIKMKQFLSDE--QNVLALRTIQVRQR 633
KL G+E F +M ++L + Q + ALR +++
Sbjct: 367 SKLK-SGRETFRRMWKWLQEPEFQRMSALRLAACKRK 402
Score = 62.8 bits (151), Expect = 2e-09
Identities = 30/67 (44%), Positives = 46/67 (68%), Gaps = 1/67 (1%)
Query: 895 EVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIR 954
E++T E+ +++ +L + I Q IF +++L SQG++SD+L PKPWSKL + GRE F R
Sbjct: 320 EINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKL-KSGRETFRR 378
Query: 955 MQLWLSD 961
M WL +
Sbjct: 379 MWKWLQE 385
>gi|24307887 one cut homeobox 1 [Homo sapiens]
Length = 465
Score = 77.4 bits (189), Expect = 9e-14
Identities = 62/213 (29%), Positives = 98/213 (46%), Gaps = 35/213 (16%)
Query: 1022 SLSGKMYSGSQAPGGIQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGS 1081
S++G S G ++EI +T + +R+ L ++ Q +F + +L +QG+
Sbjct: 274 SVTGAQVSNGSNSGQMEEI-------NTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGT 326
Query: 1082 VSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLISTG 1141
+SDLL PKPW KL GRE F RM WL +P + + M L + A KR+
Sbjct: 327 LSDLLRNPKPWSKLK-SGRETFRRMWKWLQEP----EFQRMSAL-RLAACKRK------- 373
Query: 1142 SDSESPATRSECPSPCLQPQDLSLLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIELL 1201
+ E R P KKPR+V ++ L ++ PS++ +
Sbjct: 374 -EQEHGKDRGNTP--------------KKPRLVFTDVQRRTLHAIFKENKRPSKELQITI 418
Query: 1202 SFQLNLKTNTVINWFHNYRSRMRREMLVEGTQD 1234
S QL L+ +TV N+F N R R + EG+ +
Sbjct: 419 SQQLGLELSTVSNFFMNARRRSLDKWQDEGSSN 451
Score = 63.2 bits (152), Expect = 2e-09
Identities = 31/67 (46%), Positives = 46/67 (68%), Gaps = 1/67 (1%)
Query: 895 EVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIR 954
E++T E+ +++ +L + I Q IF ++VL SQG++SD+L PKPWSKL + GRE F R
Sbjct: 291 EINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKL-KSGRETFRR 349
Query: 955 MQLWLSD 961
M WL +
Sbjct: 350 MWKWLQE 356
Score = 58.2 bits (139), Expect = 6e-08
Identities = 45/151 (29%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 487 GERLMMPPAAFKGEAGGLLVFPP-AFYGAKPPTAPATPAPGPEP-LGGPEPADGGGGGAA 544
GE+ + P +A GL P A A+ A P P + G + ++G G
Sbjct: 230 GEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSG-- 287
Query: 545 GPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVK 604
+ E+++T E+A ++ +L +++I Q +F VL SQG++S++L PKPW KL
Sbjct: 288 ----QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLK-S 342
Query: 605 GKEPFIKMKQFLSDE--QNVLALRTIQVRQR 633
G+E F +M ++L + Q + ALR +++
Sbjct: 343 GRETFRRMWKWLQEPEFQRMSALRLAACKRK 373
>gi|119220564 one cut domain, family member 2 [Homo sapiens]
Length = 504
Score = 68.6 bits (166), Expect = 4e-11
Identities = 68/226 (30%), Positives = 98/226 (43%), Gaps = 40/226 (17%)
Query: 436 EQSYPSPQQLPPP----PGPEDPLSPSPGQPL---LG---------PSLGPDG-----TR 474
E+ P+ L P PG LSP PL LG P+ GP G +
Sbjct: 201 ERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSP 260
Query: 475 TFSLSPFPSLASGER-----LMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEP 529
F L GE+ L PPAA GL P P AP+ P
Sbjct: 261 NFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLH-HPGHTQSHGPVLAPSRERP---- 315
Query: 530 LGGPEPADGGGGGAAGPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVS 589
P+ G A G EE ++T E+A ++ +L +++I Q +F VL SQG++S
Sbjct: 316 -----PSSSSGSQVATSGQLEE-INTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLS 369
Query: 590 EILARPKPWRKLTVKGKEPFIKMKQFLSDE--QNVLALRTIQVRQR 633
++L PKPW KL G+E F +M ++L + Q + ALR +++
Sbjct: 370 DLLRNPKPWSKLK-SGRETFRRMWKWLQEPEFQRMSALRLAACKRK 414
Score = 67.8 bits (164), Expect = 8e-11
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 28/177 (15%)
Query: 1046 ELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVR 1105
E++T + +R+ L ++ Q +F + +L +QG++SDLL PKPW KL GRE F R
Sbjct: 332 EINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLK-SGRETFRR 390
Query: 1106 MQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLISTGSDSESPATRSECPSPCLQPQDLSL 1165
M WL +P + + M L A ++ ++S+
Sbjct: 391 MWKWLQEP----EFQRMSALRLAACKRKEQEPNKDRNNSQ-------------------- 426
Query: 1166 LQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSR 1222
KK R+V ++ L ++ PS++ +S QL L+ TV N+F N R R
Sbjct: 427 ---KKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRR 480
Score = 63.9 bits (154), Expect = 1e-09
Identities = 43/142 (30%), Positives = 69/142 (48%), Gaps = 19/142 (13%)
Query: 895 EVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIR 954
E++T E+ +++ +L + I Q IF ++VL SQG++SD+L PKPWSKL + GRE F R
Sbjct: 332 EINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKL-KSGRETFRR 390
Query: 955 MQLWLSDQLGQAVGQQPGASQASPTEPRSSPSPPPSPTEPEKSSQEPLSLSLES------ 1008
M WL Q+P + S + P + +SQ+ L
Sbjct: 391 MWKWL---------QEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTL 441
Query: 1009 ---SKENQQPEGRSSSSLSGKM 1027
KEN++P ++S ++
Sbjct: 442 FAIFKENKRPSKEMQITISQQL 463
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 64.3 bits (155), Expect = 8e-10
Identities = 66/242 (27%), Positives = 114/242 (47%), Gaps = 30/242 (12%)
Query: 139 PELLSPKEQREGTSPAGPTLTEGS---RLPGIPGKALLTETLLQRNEAEK----QKGLQE 191
P L SP ++ EG L E RL KA L E + + E+ + +QE
Sbjct: 74 PPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQE 133
Query: 192 VQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQ 251
Q L RL EA ++ K E LE + +Y EE A AD + + + E A +
Sbjct: 134 QQADLQRRLKEARKEAK-----------EALEAKERYMEEMADTADAIEMATLDKEMAEE 182
Query: 252 RAEAAQREVESLREQLASVNSSIRL--ACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
RAE+ Q+EVE+L+E++ + + + + A +G G ++ L A L ++
Sbjct: 183 RAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARL----KD 238
Query: 310 ILRLLKDVQHLQSSLQELEEASANQIADLERQ-LTAKSEAIEKLEEKL-QAQSDYEEIKT 367
L ++D+ SS ++ E ++ + + Q L + E+L+E+L QA+S +E+K
Sbjct: 239 ALVRMRDL----SSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE 294
Query: 368 EL 369
++
Sbjct: 295 QV 296
Score = 41.6 bits (96), Expect = 0.006
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 19/203 (9%)
Query: 175 ETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLE---------LR 225
E+L Q EA K++ + E+ L E EEK A + Q + LE L
Sbjct: 185 ESLQQEVEALKER-VDELTTDLEILKAEIEEKGS--DGAASSYQLKQLEEQNARLKDALV 241
Query: 226 RKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPS 285
R D ++ K + V L +EK NQ E +++ E L+E+L+ S+I
Sbjct: 242 RMRDLSSSEKQEHVKL-QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL 300
Query: 286 GDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAK 345
G + + + L L K RE+ + D++ + EL+E + +L QL
Sbjct: 301 GAEEMVEMLTDRNLN--LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMA 358
Query: 346 SEAIEKLEEKLQAQ----SDYEE 364
+ + +++++A +DY++
Sbjct: 359 GARVREAQKRVEAAQETVADYQQ 381
Score = 34.3 bits (77), Expect = 0.92
Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 63/298 (21%)
Query: 17 LRRLQK---ELNSVASELSARQEESEHSHKHLIELRREFKKNVP------EEI------- 60
L+ L+K +L V S QE+ + L E R+E K+ + EE+
Sbjct: 111 LKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAI 170
Query: 61 ------REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDD 114
+EM +S Q EV AL +R E L + K IE + +
Sbjct: 171 EMATLDKEMAEERAESLQQEVEALKERVDEL-TTDLEILKAEIEEKGSDGAASSYQLKQL 229
Query: 115 RLQPPSFDPSGQPRRDLHTS------------WKRNPELLSPKEQR----EGTSPAGPTL 158
Q + RDL +S K+N EL ++QR E S A T+
Sbjct: 230 EEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTI 289
Query: 159 TEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQ 218
E + + + G +E+ L R EEK++ L +
Sbjct: 290 DE------------------LKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGD-- 329
Query: 219 AELLELRRKYDEEAASKADEVGL-IMTNLEKANQRAEAAQREVESLREQLASVNSSIR 275
LE + ++E A E L + L+ A R AQ+ VE+ +E +A +I+
Sbjct: 330 ---LEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIK 384
Score = 31.2 bits (69), Expect = 7.8
Identities = 21/85 (24%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Query: 181 NEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVG 240
+EA + L E ++ AA+ +A+E+I+ + + L+ TQA L + ++++E + ++
Sbjct: 833 SEANVRLSLLEKKLDSAAK--DADERIEKVQTRLEETQALLRKKEKEFEETMDALQADID 890
Query: 241 LIMTNLEKANQRAEA-AQREVESLR 264
+ + QR + ++R +E LR
Sbjct: 891 QLEAEKAELKQRLNSQSKRTIEGLR 915
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 64.3 bits (155), Expect = 8e-10
Identities = 66/242 (27%), Positives = 114/242 (47%), Gaps = 30/242 (12%)
Query: 139 PELLSPKEQREGTSPAGPTLTEGS---RLPGIPGKALLTETLLQRNEAEK----QKGLQE 191
P L SP ++ EG L E RL KA L E + + E+ + +QE
Sbjct: 188 PPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQE 247
Query: 192 VQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQ 251
Q L RL EA ++ K E LE + +Y EE A AD + + + E A +
Sbjct: 248 QQADLQRRLKEARKEAK-----------EALEAKERYMEEMADTADAIEMATLDKEMAEE 296
Query: 252 RAEAAQREVESLREQLASVNSSIRL--ACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
RAE+ Q+EVE+L+E++ + + + + A +G G ++ L A L ++
Sbjct: 297 RAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARL----KD 352
Query: 310 ILRLLKDVQHLQSSLQELEEASANQIADLERQ-LTAKSEAIEKLEEKL-QAQSDYEEIKT 367
L ++D+ SS ++ E ++ + + Q L + E+L+E+L QA+S +E+K
Sbjct: 353 ALVRMRDL----SSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE 408
Query: 368 EL 369
++
Sbjct: 409 QV 410
Score = 41.6 bits (96), Expect = 0.006
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 19/203 (9%)
Query: 175 ETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLE---------LR 225
E+L Q EA K++ + E+ L E EEK A + Q + LE L
Sbjct: 299 ESLQQEVEALKER-VDELTTDLEILKAEIEEKGS--DGAASSYQLKQLEEQNARLKDALV 355
Query: 226 RKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPS 285
R D ++ K + V L +EK NQ E +++ E L+E+L+ S+I
Sbjct: 356 RMRDLSSSEKQEHVKL-QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL 414
Query: 286 GDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAK 345
G + + + L L K RE+ + D++ + EL+E + +L QL
Sbjct: 415 GAEEMVEMLTDRNLN--LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMA 472
Query: 346 SEAIEKLEEKLQAQ----SDYEE 364
+ + +++++A +DY++
Sbjct: 473 GARVREAQKRVEAAQETVADYQQ 495
Score = 34.3 bits (77), Expect = 0.92
Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 63/298 (21%)
Query: 17 LRRLQK---ELNSVASELSARQEESEHSHKHLIELRREFKKNVP------EEI------- 60
L+ L+K +L V S QE+ + L E R+E K+ + EE+
Sbjct: 225 LKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAI 284
Query: 61 ------REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDD 114
+EM +S Q EV AL +R E L + K IE + +
Sbjct: 285 EMATLDKEMAEERAESLQQEVEALKERVDEL-TTDLEILKAEIEEKGSDGAASSYQLKQL 343
Query: 115 RLQPPSFDPSGQPRRDLHTS------------WKRNPELLSPKEQR----EGTSPAGPTL 158
Q + RDL +S K+N EL ++QR E S A T+
Sbjct: 344 EEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTI 403
Query: 159 TEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQ 218
E + + + G +E+ L R EEK++ L +
Sbjct: 404 DE------------------LKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGD-- 443
Query: 219 AELLELRRKYDEEAASKADEVGL-IMTNLEKANQRAEAAQREVESLREQLASVNSSIR 275
LE + ++E A E L + L+ A R AQ+ VE+ +E +A +I+
Sbjct: 444 ---LEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIK 498
Score = 31.2 bits (69), Expect = 7.8
Identities = 21/85 (24%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Query: 181 NEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVG 240
+EA + L E ++ AA+ +A+E+I+ + + L+ TQA L + ++++E + ++
Sbjct: 947 SEANVRLSLLEKKLDSAAK--DADERIEKVQTRLEETQALLRKKEKEFEETMDALQADID 1004
Query: 241 LIMTNLEKANQRAEA-AQREVESLR 264
+ + QR + ++R +E LR
Sbjct: 1005 QLEAEKAELKQRLNSQSKRTIEGLR 1029
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 64.3 bits (155), Expect = 8e-10
Identities = 66/242 (27%), Positives = 114/242 (47%), Gaps = 30/242 (12%)
Query: 139 PELLSPKEQREGTSPAGPTLTEGS---RLPGIPGKALLTETLLQRNEAEK----QKGLQE 191
P L SP ++ EG L E RL KA L E + + E+ + +QE
Sbjct: 74 PPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQE 133
Query: 192 VQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQ 251
Q L RL EA ++ K E LE + +Y EE A AD + + + E A +
Sbjct: 134 QQADLQRRLKEARKEAK-----------EALEAKERYMEEMADTADAIEMATLDKEMAEE 182
Query: 252 RAEAAQREVESLREQLASVNSSIRL--ACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
RAE+ Q+EVE+L+E++ + + + + A +G G ++ L A L ++
Sbjct: 183 RAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARL----KD 238
Query: 310 ILRLLKDVQHLQSSLQELEEASANQIADLERQ-LTAKSEAIEKLEEKL-QAQSDYEEIKT 367
L ++D+ SS ++ E ++ + + Q L + E+L+E+L QA+S +E+K
Sbjct: 239 ALVRMRDL----SSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE 294
Query: 368 EL 369
++
Sbjct: 295 QV 296
Score = 41.6 bits (96), Expect = 0.006
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 19/203 (9%)
Query: 175 ETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLE---------LR 225
E+L Q EA K++ + E+ L E EEK A + Q + LE L
Sbjct: 185 ESLQQEVEALKER-VDELTTDLEILKAEIEEKGS--DGAASSYQLKQLEEQNARLKDALV 241
Query: 226 RKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPS 285
R D ++ K + V L +EK NQ E +++ E L+E+L+ S+I
Sbjct: 242 RMRDLSSSEKQEHVKL-QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL 300
Query: 286 GDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAK 345
G + + + L L K RE+ + D++ + EL+E + +L QL
Sbjct: 301 GAEEMVEMLTDRNLN--LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMA 358
Query: 346 SEAIEKLEEKLQAQ----SDYEE 364
+ + +++++A +DY++
Sbjct: 359 GARVREAQKRVEAAQETVADYQQ 381
Score = 34.3 bits (77), Expect = 0.92
Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 63/298 (21%)
Query: 17 LRRLQK---ELNSVASELSARQEESEHSHKHLIELRREFKKNVP------EEI------- 60
L+ L+K +L V S QE+ + L E R+E K+ + EE+
Sbjct: 111 LKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAI 170
Query: 61 ------REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDD 114
+EM +S Q EV AL +R E L + K IE + +
Sbjct: 171 EMATLDKEMAEERAESLQQEVEALKERVDEL-TTDLEILKAEIEEKGSDGAASSYQLKQL 229
Query: 115 RLQPPSFDPSGQPRRDLHTS------------WKRNPELLSPKEQR----EGTSPAGPTL 158
Q + RDL +S K+N EL ++QR E S A T+
Sbjct: 230 EEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTI 289
Query: 159 TEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQ 218
E + + + G +E+ L R EEK++ L +
Sbjct: 290 DE------------------LKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGD-- 329
Query: 219 AELLELRRKYDEEAASKADEVGL-IMTNLEKANQRAEAAQREVESLREQLASVNSSIR 275
LE + ++E A E L + L+ A R AQ+ VE+ +E +A +I+
Sbjct: 330 ---LEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIK 384
Score = 31.2 bits (69), Expect = 7.8
Identities = 21/85 (24%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Query: 181 NEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVG 240
+EA + L E ++ AA+ +A+E+I+ + + L+ TQA L + ++++E + ++
Sbjct: 833 SEANVRLSLLEKKLDSAAK--DADERIEKVQTRLEETQALLRKKEKEFEETMDALQADID 890
Query: 241 LIMTNLEKANQRAEA-AQREVESLR 264
+ + QR + ++R +E LR
Sbjct: 891 QLEAEKAELKQRLNSQSKRTIEGLR 915
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 64.3 bits (155), Expect = 8e-10
Identities = 66/242 (27%), Positives = 114/242 (47%), Gaps = 30/242 (12%)
Query: 139 PELLSPKEQREGTSPAGPTLTEGS---RLPGIPGKALLTETLLQRNEAEK----QKGLQE 191
P L SP ++ EG L E RL KA L E + + E+ + +QE
Sbjct: 208 PPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQE 267
Query: 192 VQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQ 251
Q L RL EA ++ K E LE + +Y EE A AD + + + E A +
Sbjct: 268 QQADLQRRLKEARKEAK-----------EALEAKERYMEEMADTADAIEMATLDKEMAEE 316
Query: 252 RAEAAQREVESLREQLASVNSSIRL--ACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
RAE+ Q+EVE+L+E++ + + + + A +G G ++ L A L ++
Sbjct: 317 RAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARL----KD 372
Query: 310 ILRLLKDVQHLQSSLQELEEASANQIADLERQ-LTAKSEAIEKLEEKL-QAQSDYEEIKT 367
L ++D+ SS ++ E ++ + + Q L + E+L+E+L QA+S +E+K
Sbjct: 373 ALVRMRDL----SSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE 428
Query: 368 EL 369
++
Sbjct: 429 QV 430
Score = 41.6 bits (96), Expect = 0.006
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 19/203 (9%)
Query: 175 ETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLE---------LR 225
E+L Q EA K++ + E+ L E EEK A + Q + LE L
Sbjct: 319 ESLQQEVEALKER-VDELTTDLEILKAEIEEKGS--DGAASSYQLKQLEEQNARLKDALV 375
Query: 226 RKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPS 285
R D ++ K + V L +EK NQ E +++ E L+E+L+ S+I
Sbjct: 376 RMRDLSSSEKQEHVKL-QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL 434
Query: 286 GDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAK 345
G + + + L L K RE+ + D++ + EL+E + +L QL
Sbjct: 435 GAEEMVEMLTDRNLN--LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMA 492
Query: 346 SEAIEKLEEKLQAQ----SDYEE 364
+ + +++++A +DY++
Sbjct: 493 GARVREAQKRVEAAQETVADYQQ 515
Score = 34.3 bits (77), Expect = 0.92
Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 63/298 (21%)
Query: 17 LRRLQK---ELNSVASELSARQEESEHSHKHLIELRREFKKNVP------EEI------- 60
L+ L+K +L V S QE+ + L E R+E K+ + EE+
Sbjct: 245 LKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAI 304
Query: 61 ------REMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDD 114
+EM +S Q EV AL +R E L + K IE + +
Sbjct: 305 EMATLDKEMAEERAESLQQEVEALKERVDEL-TTDLEILKAEIEEKGSDGAASSYQLKQL 363
Query: 115 RLQPPSFDPSGQPRRDLHTS------------WKRNPELLSPKEQR----EGTSPAGPTL 158
Q + RDL +S K+N EL ++QR E S A T+
Sbjct: 364 EEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTI 423
Query: 159 TEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQ 218
E + + + G +E+ L R EEK++ L +
Sbjct: 424 DE------------------LKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGD-- 463
Query: 219 AELLELRRKYDEEAASKADEVGL-IMTNLEKANQRAEAAQREVESLREQLASVNSSIR 275
LE + ++E A E L + L+ A R AQ+ VE+ +E +A +I+
Sbjct: 464 ---LEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIK 518
Score = 31.2 bits (69), Expect = 7.8
Identities = 21/85 (24%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Query: 181 NEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVG 240
+EA + L E ++ AA+ +A+E+I+ + + L+ TQA L + ++++E + ++
Sbjct: 967 SEANVRLSLLEKKLDSAAK--DADERIEKVQTRLEETQALLRKKEKEFEETMDALQADID 1024
Query: 241 LIMTNLEKANQRAEA-AQREVESLR 264
+ + QR + ++R +E LR
Sbjct: 1025 QLEAEKAELKQRLNSQSKRTIEGLR 1049
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 62.0 bits (149), Expect = 4e-09
Identities = 94/434 (21%), Positives = 176/434 (40%), Gaps = 88/434 (20%)
Query: 16 DLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQAEV 75
DLR +Q+E + +LS + + E + L +L +E K+ EE+ ++ E
Sbjct: 681 DLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQ--EEVLARAVQEKEALVREK 738
Query: 76 VALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHTSW 135
AL R Q E + +QL + S + L+ F+ Q
Sbjct: 739 AALEVRLQAVERDRQDLAEQL----------QGLSSAKELLESSLFEAQQQ--------- 779
Query: 136 KRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQIT 195
N + K Q E T+T+ + + L E +R++AE+++
Sbjct: 780 --NSVIEVTKGQLEVQIQ---TVTQAKEVIQGEVRCLKLELDTERSQAEQERD------A 828
Query: 196 LAARLGEAEEKIKVLHSALKAT-QAELLELRRKYDEEAASKADEVGLIMTNLEK----AN 250
A +L +AE++ K KA + E+ +LR K+++E + E+ + +LE+
Sbjct: 829 AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELE 888
Query: 251 QRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDREI 310
R + Q E+E+++ Q + A C Q + + L + + + LA +++
Sbjct: 889 MRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQL 948
Query: 311 LRLLKDVQ---------------HLQSSLQELEEAS------------------------ 331
RL +D++ LQ + +EL+EA+
Sbjct: 949 ERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDL 1008
Query: 332 ANQIADLERQLTAKSEA----IEKLEEKLQAQSDYEEIKTELSILKAMKLASSTCSLPQG 387
Q+ DL+ QL A+ ++ ++++EKL+ +Y I+ EL KA SL
Sbjct: 1009 QKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKA--------SLTLS 1060
Query: 388 MAKPEDSLLIAKEA 401
+ + E LL+ +EA
Sbjct: 1061 LMEKEQRLLVLQEA 1074
Score = 44.7 bits (104), Expect = 7e-04
Identities = 58/212 (27%), Positives = 91/212 (42%), Gaps = 30/212 (14%)
Query: 175 ETLLQRNEAEKQKGLQEVQITLAARLGEA-EEKIKVLHSALKATQAELLELRRKYDEEAA 233
E LQ + A+ QK Q+ ++ LA R E +E + L + + +EL+ LR E +
Sbjct: 495 ELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREAL-ESSH 553
Query: 234 SKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCS----PQGPSGDKV 289
+ + + T + A RAE + E+ S L + + +R A + + DKV
Sbjct: 554 LEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKV 613
Query: 290 ------------NFTLCSGPRLEAA----------LASKDREILRLLKDVQHLQSSLQEL 327
N ++CS R+EAA LA ++ L + HL++ LQ+
Sbjct: 614 GLNQQLLQLEEENQSVCS--RMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKA 671
Query: 328 EEASANQIADLERQLTAKSEAIEKLEEKLQAQ 359
EEA A ADL K E +KL E Q
Sbjct: 672 EEAGAELQADLRDIQEEKEEIQKKLSESRHQQ 703
Score = 40.8 bits (94), Expect = 0.010
Identities = 50/217 (23%), Positives = 92/217 (42%), Gaps = 35/217 (16%)
Query: 169 GKALLTETLLQRNEAEKQKG--------LQEVQITLAARLGEAEEKIKVLHSALKATQAE 220
G+ L T+ L + AE+ KG L+ +++ L + E E + + +H E
Sbjct: 1696 GRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIH--------E 1747
Query: 221 LLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCS 280
L EL+ + +++ +VG L + Q Q++++ REQ S++
Sbjct: 1748 LQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDE 1807
Query: 281 PQGPSGDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQEL-EEASANQIADLE 339
Q ALA +D+E+ L ++ Q Q + + E+A A Q A +
Sbjct: 1808 AQ------------------RALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQ 1849
Query: 340 RQLTAKSEAIEKLEEKLQAQSDYEEIKTELSILKAMK 376
+T K E + K QA+ EE+ E ++A++
Sbjct: 1850 AHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALE 1886
Score = 40.4 bits (93), Expect = 0.013
Identities = 90/393 (22%), Positives = 164/393 (41%), Gaps = 53/393 (13%)
Query: 13 KRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQ 72
+R ++ L+++L ++ Q++ + + LR+ +K E R+ +A Q
Sbjct: 398 RRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGE--RDTLAGQTVDLQ 455
Query: 73 AEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEA--ARSLDDRLQPPSFDPSGQP--- 127
EV +LSK + + A + +QL V EA R ++ LQ GQ
Sbjct: 456 GEVDSLSKERELLQKAREELRQQL-----EVLEQEAWRLRRVNVELQLQGDSAQGQKEEQ 510
Query: 128 RRDLHTSWK---RNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAE 184
+ +LH + + R E+L E ++ S L+E L + L LL++ + E
Sbjct: 511 QEELHLAVRERERLQEMLMGLEAKQSES-----LSELITLREALESSHLEGELLRQEQTE 565
Query: 185 KQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLI-- 242
L + ++A L +E +K + L+A +L L A D+VGL
Sbjct: 566 VTAALARAEQSIA-ELSSSENTLKTEVADLRAAAVKLSALNE------ALALDKVGLNQQ 618
Query: 243 MTNLEKANQ----RAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPR 298
+ LE+ NQ R EAA++ +L+ LA R A ++ +G
Sbjct: 619 LLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKR-REALWEKNTHLEAQLQKAEEAGAE 677
Query: 299 LEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEK------- 351
L+A L R+I +++Q S + +EA+ Q+ L ++ + E + +
Sbjct: 678 LQADL----RDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEA 733
Query: 352 -------LEEKLQA-QSDYEEIKTELSILKAMK 376
LE +LQA + D +++ +L L + K
Sbjct: 734 LVREKAALEVRLQAVERDRQDLAEQLQGLSSAK 766
Score = 40.4 bits (93), Expect = 0.013
Identities = 52/253 (20%), Positives = 103/253 (40%), Gaps = 54/253 (21%)
Query: 178 LQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYD-------- 229
L +N+ EK K + Q +L + L E E + L S L+ + + +E + + +
Sbjct: 1294 LSQNQEEKSKW-EGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKEN 1352
Query: 230 ------------EEAASKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLA 277
EA ++A G++ +L A + EVES RE+ ++
Sbjct: 1353 LTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQ------ 1406
Query: 278 CCSPQGPSGDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIAD 337
++ + G L+ LA + + ++V+ L+ +QELE+ Q A
Sbjct: 1407 ---------EQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAA 1457
Query: 338 LE---RQLTAKSEAIEKLEEKLQAQSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDS 394
LE L +++ ++ +E++Q E++ S+L+ LP + + E
Sbjct: 1458 LELLSLDLKKRNQEVDLQQEQIQ------ELEKCRSVLE---------HLPMAVQEREQK 1502
Query: 395 LLIAKEAFFPTQK 407
L + +E +K
Sbjct: 1503 LTVQREQIRELEK 1515
Score = 37.4 bits (85), Expect = 0.11
Identities = 105/481 (21%), Positives = 190/481 (39%), Gaps = 86/481 (17%)
Query: 14 RFDLRRLQKELNSVASELSARQEESEHSHK-------HLIELRREFKKNVP--------- 57
+ LR +EL + + R EE + K H+ + R+ +K V
Sbjct: 1689 KLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHEL 1748
Query: 58 EEIREMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQ 117
+E+++ + L+ +V S + E + + +QL EA + + E +SL +L
Sbjct: 1749 QELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKE--QSLQSQLD 1806
Query: 118 PPSFDPSGQPRRDLHTSWKRNPELLS-PKEQREGTSPAGPTLTEGSRLPGIPGKALLTET 176
+ +R L +R+ EL + +EQ++ + L G +A +T
Sbjct: 1807 --------EAQRALA---QRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMT-- 1853
Query: 177 LLQRN-----EAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEE 231
L +R+ E+ + L+E R+ EE + L + + + LL L+++ E+
Sbjct: 1854 LKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQ 1913
Query: 232 AASKADEVGLIMTNLEKANQRAEAAQREVESLREQLAS--------------VNSSIRLA 277
A E + + +A + +E+E+LR + S + ++ A
Sbjct: 1914 AQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKA 1973
Query: 278 CCSPQGPSGD------------------KVNFTLCS--GPRLEAALASKDREI----LRL 313
+ QG + + C +LE AL ++ EI LR
Sbjct: 1974 HAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRY 2033
Query: 314 LKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEIKTELSILK 373
+DVQ LQ +L + +E +Q QL KS A E +Q + + + + E I
Sbjct: 2034 QEDVQQLQQALAQRDEELRHQ--QEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEI-- 2089
Query: 374 AMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPEEDPSEDDSIK-DS 432
L S L +A+ E +L +E Q+ LE +L S + P E+ S+K DS
Sbjct: 2090 -RGLHQSVRELQLTLAQKEQEILELRET---QQRNNLE--ALPHSHKTSPMEEQSLKLDS 2143
Query: 433 L 433
L
Sbjct: 2144 L 2144
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 61.6 bits (148), Expect = 5e-09
Identities = 58/210 (27%), Positives = 85/210 (40%), Gaps = 16/210 (7%)
Query: 1235 EPDLDPSGGPGILPPGHSHPDPTPQSPDSETEDQKPTVKELE--LQEGPEE-NSTPLTTQ 1291
+P L P+ G ++P G P+P PQS +E+ TV L++GP + +P +
Sbjct: 524 QPPLPPTDGSTVVPAG---PEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 580
Query: 1292 DKAQVRIKQEQMEEDAEEEAGSQPQ---DSGELDKGQGPPKEEHPDPPG-NDGLPKVAPG 1347
D + +QPQ S +L GQ P P P + K AP
Sbjct: 581 DPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQ-PHNAAGPSPHTLRRAVKKPAPA 639
Query: 1348 PLLPGGSTPDCPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLM 1407
P PG P HP +S +G HP LS K + S + + P S+P +
Sbjct: 640 PPKPGNPPPG----HPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQL 695
Query: 1408 MSVSPVPSSSAPISPSPPGAPPAKVPSASP 1437
+ SS +PI +P PP A+P
Sbjct: 696 SAPRRYSSSLSPIQ-APNHPPPQPPTQATP 724
Score = 38.1 bits (87), Expect = 0.064
Identities = 35/113 (30%), Positives = 47/113 (41%), Gaps = 10/113 (8%)
Query: 419 PEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSL 478
P + P++ + + Q P+P LP G E P S +P Q PS P G + SL
Sbjct: 715 PPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQP-SHTPPQTPTPPSTPPLGKQNPSL 773
Query: 479 SPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLG 531
+LA G P + AG L P KP P+ P P P+P G
Sbjct: 774 PAPQTLAGGN-----PETAQPHAGTL---PRPRPVPKPRNRPSVPPP-PQPPG 817
Score = 36.6 bits (83), Expect = 0.19
Identities = 38/137 (27%), Positives = 55/137 (40%), Gaps = 22/137 (16%)
Query: 412 KPSLLASPEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPD 471
+P +S E S ++ S G + PSP PP P+DP+S + P+ G +
Sbjct: 541 EPPPQSSRAESSSGGGTVPSSAGILEQGPSPGD-GSPPKPKDPVSAAV------PAPGRN 593
Query: 472 GTRTFSLSPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPT---APATPAPGPE 528
++ +ASG+ P A G + P G P T A PAP P
Sbjct: 594 NSQ---------IASGQN---QPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPP 641
Query: 529 PLGGPEPADGGGGGAAG 545
G P P GG ++G
Sbjct: 642 KPGNPPPGHPGGQSSSG 658
Score = 35.8 bits (81), Expect = 0.32
Identities = 42/152 (27%), Positives = 53/152 (34%), Gaps = 25/152 (16%)
Query: 419 PEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPS---PGQPLLGPSLGPDGTRT 475
P P + S GT Q PS PP P P + PGQP L +
Sbjct: 643 PGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYS 702
Query: 476 FSLSPF----------PSLASGERLMMP-------PAAFKGEAGGLLVFPPAFYGAKPPT 518
SLSP P+ A+ P P A E G + P+ + PT
Sbjct: 703 SSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHG---LEQPSHTPPQTPT 759
Query: 519 APATPAPGPE--PLGGPEPADGGGGGAAGPGA 548
P+TP G + L P+ GG A P A
Sbjct: 760 PPSTPPLGKQNPSLPAPQTLAGGNPETAQPHA 791
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 60.1 bits (144), Expect = 2e-08
Identities = 83/356 (23%), Positives = 143/356 (40%), Gaps = 40/356 (11%)
Query: 16 DLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKK--NVPEEIREMVAPVLKSFQA 73
++ LQ++L E + + E + + ++ E K+ + IR+ VA + + +
Sbjct: 1528 EVELLQQKLREKLDEFNELAIQKESADRQVLMQEEEIKRLEEMNINIRKKVAQLQEEVEK 1587
Query: 74 EVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHT 133
+ + Q+ E L+ A +A R + PPS P P L
Sbjct: 1588 QKNIVKGLEQDKEVLKKQQMSSLLLASTLQSTLDAGRCPE----PPSGSPPEGPEIQLEV 1643
Query: 134 SWK----RNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGL 189
+ + R E+L KEQ E + E + ++T + E E++
Sbjct: 1644 TQRALLRRESEVLDLKEQLEKMKGDLESKNEEILHLNLKLDMQNSQTAVSLRELEEENTS 1703
Query: 190 QEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
+V T R E EE LKAT L E +++ +E A + +++ ++ L+
Sbjct: 1704 LKVIYT---RSSEIEE--------LKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHE 1752
Query: 250 NQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
EV Q S+ S L C GP G + LEAAL +K+
Sbjct: 1753 LSLMGPVVHEVSD--SQAGSLQSE--LLCSQAGGPRGQALQ------GELEAALEAKEA- 1801
Query: 310 ILRLLKD--------VQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQ 357
+ RLL D ++ LQ LQ EEA+ Q+A+LER + + +E + ++Q
Sbjct: 1802 LSRLLADQERRHSQALEALQQRLQGAEEAAELQLAELERNVALREAEVEDMASRIQ 1857
Score = 39.7 bits (91), Expect = 0.022
Identities = 77/384 (20%), Positives = 147/384 (38%), Gaps = 48/384 (12%)
Query: 16 DLRRLQKELNSVASELSARQEESEHSHKHL------IELRREFKKNVPEEIREMVAPVLK 69
+L L+++L A E +A +EE E R + E++ + + K
Sbjct: 1364 ELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAREAALRKEVEDLTKEQSETRK 1423
Query: 70 SFQAEVVALSKRSQEAEAAF---LSVYKQLIEAPDPVPVFEA-ARSLDDRL--QPPSFDP 123
+ + AL + + E+ LS ++ + + V E SLD L Q D
Sbjct: 1424 QAEKDRSALLSQMKILESELEEQLSQHRGCAKQAEAVTALEQQVASLDKHLRNQRQFMDE 1483
Query: 124 SGQPRRDLHTSWKRNPELLSPK-EQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNE 182
R +++ + L + Q P GP ++ + L G LLQ+
Sbjct: 1484 QAAEREHEREEFQQEIQRLEGQLRQAAKPQPWGPRDSQQAPLDG-------EVELLQQKL 1536
Query: 183 AEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLI 242
EK E LA + A+ ++ + +K + + +R+K V +
Sbjct: 1537 REKLDEFNE----LAIQKESADRQVLMQEEEIKRLEEMNINIRKK-----------VAQL 1581
Query: 243 MTNLEKANQRAEAAQREVESLREQ------LASVNSSIRLACCSPQGPSGDKVNFTLCSG 296
+EK + +++ E L++Q LAS S A P+ PSG
Sbjct: 1582 QEEVEKQKNIVKGLEQDKEVLKKQQMSSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQL 1641
Query: 297 PRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEK- 355
+ AL ++ E+L L + ++ ++ L+ E + L+ Q + + ++ +LEE+
Sbjct: 1642 EVTQRALLRRESEVLDLKEQLEKMKGDLESKNEEILHLNLKLDMQNSQTAVSLRELEEEN 1701
Query: 356 ------LQAQSDYEEIKTELSILK 373
S+ EE+K + L+
Sbjct: 1702 TSLKVIYTRSSEIEELKATIENLQ 1725
Score = 37.7 bits (86), Expect = 0.083
Identities = 53/204 (25%), Positives = 86/204 (42%), Gaps = 36/204 (17%)
Query: 184 EKQKGLQEVQITLAARLGEAEEKIKVLHSA-LKATQAELLELRRKYDEEAASKADEVGLI 242
E + GL + Q L + +H+A L+ TQA L +K E A ++ E
Sbjct: 231 EDEAGLHQSQAVHGLELEALRLSLSNMHTAQLELTQANL----QKEKETALTELRE---- 282
Query: 243 MTNLEKANQRA---EAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRL 299
M N +A + A Q E+E LREQ A + L C +K+ + ++
Sbjct: 283 MLNSRRAQELALLQSRQQHELELLREQHAREKEEVVLRCGQEAAELKEKLQSEMEKNAQI 342
Query: 300 EAAL-----ASKDREILRLLKDVQ-HLQSSLQEL----EEASANQIADLERQLTAKSE-- 347
L + KD + L K++ QS +++L ++ A Q A+LE+ K++
Sbjct: 343 VKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAE 402
Query: 348 ------------AIEKLEEKLQAQ 359
AIEKL E LQ++
Sbjct: 403 RALRNLESHHQAAIEKLREDLQSE 426
Score = 36.6 bits (83), Expect = 0.19
Identities = 54/262 (20%), Positives = 106/262 (40%), Gaps = 38/262 (14%)
Query: 186 QKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTN 245
Q G E AAR+ E + KV S L+ E +EL + + K + +
Sbjct: 656 QDGDLEADTERAARVLGLETEHKVQLSLLQTELKEEIELLKIENRNLYGKLQHETRLKDD 715
Query: 246 LEKAN--------QRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGP 297
LEK + A+++ E ++++ + ++ Q + +K+ L
Sbjct: 716 LEKVKHNLIEDHQKELNNAKQKTELMKQEFQRKETDWKVMKEELQREAEEKLTLMLLE-- 773
Query: 298 RLEAALASK-DREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKL 356
L K + E ++ + ++ +++L++ A QI DLER LT + +++LE+ L
Sbjct: 774 -----LREKAESEKQTIINKFELREAEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQDL 828
Query: 357 Q-------AQSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFP----- 404
+Q E + L A+ + C+L L++A+ F
Sbjct: 829 TSDDALHCSQCGREPPTAQDGELAALHV-KEDCAL---------QLMLARSRFLEERKEI 878
Query: 405 TQKFLLEKPSLLASPEEDPSED 426
T+KF E+ + L +E + +
Sbjct: 879 TEKFSAEQDAFLQEAQEQHARE 900
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 59.7 bits (143), Expect = 2e-08
Identities = 171/799 (21%), Positives = 303/799 (37%), Gaps = 132/799 (16%)
Query: 16 DLRRLQKELNSVASELSAR----QEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSF 71
DL+RLQ+E + EL A Q + + + L+ K+ + EEI L+
Sbjct: 994 DLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEI-----AALQQE 1048
Query: 72 QAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDL 131
+ E + L++ S++ +A L ++ + + + ++ ++ D + +D
Sbjct: 1049 RDEGLLLAE-SEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDR 1107
Query: 132 HTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQE 191
T EL + QRE + A A++ + LQE
Sbjct: 1108 STVNALTSELRDLRAQREEAAAA---------------------------HAQEVRRLQE 1140
Query: 192 VQITLAAR----LGEAEE---KIKVLHSALKATQAELLELRRKYDEEAASK---ADEVGL 241
L + L EAEE ++++L A + ELLE +RK E + E G
Sbjct: 1141 QARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGE 1200
Query: 242 IMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEA 301
+ +L + + EA +R E LR + S ++++ L + + E
Sbjct: 1201 LRRSLGEGAKEREALRRSNEELRSAVKKAES--------------ERISLKLANEDK-EQ 1245
Query: 302 ALASKDREILRLLKDVQHLQSSLQELEEA---SANQIADLERQLTAKSEAIEKLEEKLQA 358
LA + + K+ L++ LQE+E + + ++ +L RQ+ +L +L
Sbjct: 1246 KLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL-- 1303
Query: 359 QSDYEEIKTELSILKAMKLAS--STCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLL 416
E++ L++ + + S T L Q + K E SL + ++ Q+ L E+
Sbjct: 1304 ----AELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEF 1359
Query: 417 ASPEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPL-LGPSLGPDGTRT 475
+ E S++++ GTE+ QQL G E L + + LG L R
Sbjct: 1360 RTRERRLL--GSLEEARGTEK-----QQLDHARGLELKLEAARAEAAELGLRLSAAEGRA 1412
Query: 476 FSLSPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEP 535
L A R+ + A + + GGL G +PA P P P P
Sbjct: 1413 QGLE-----AELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPA-PRPVPGSPARDAP 1466
Query: 536 ADGGGGGAAGPGAEE------------------EQLDTAEIAFQVKEQLLKHNIGQRVFG 577
A+G G G P E LD + ++E L + QR
Sbjct: 1467 AEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERD 1526
Query: 578 ---------HYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNVLALRTI 628
+ L + +R + +K + +E + LS Q LAL+
Sbjct: 1527 ELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEE 1586
Query: 629 QV----RQRGSITPRIRTPETGSDDAIKSILEQAKKEIESQKGGEPKTSVAPLSI----- 679
V R+R + ++ T E S A +S L ++++I K E K +
Sbjct: 1587 SVRRSERERRATLDQVATLER-SLQATESELRASQEKISKMKANETKLEGDKRRLKEVLD 1645
Query: 680 --ANGTTPASTSEDAIKSILEQAR---REMQAQQQALLEMEVAPRGRSVPPSPPERPSLA 734
+ T +++ L+++R + +AQ QAL + V R V S + +L
Sbjct: 1646 ASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQD-RVDSLQRQVADSEVKAGTLQ 1704
Query: 735 TASQ--NGAPALVKQEEGS 751
+ NGA A V++ EG+
Sbjct: 1705 LTVERLNGALAKVEESEGA 1723
Score = 42.7 bits (99), Expect = 0.003
Identities = 52/230 (22%), Positives = 94/230 (40%), Gaps = 20/230 (8%)
Query: 177 LLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKA 236
LL R ++ LQ Q + E+++ L+A Q EL R + +EE
Sbjct: 600 LLSREKSNLAHSLQVAQ--------QQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAV 651
Query: 237 DEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSG 296
+ + LE+++++ E + + L ++L V ++ A +K
Sbjct: 652 QDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEAL- 710
Query: 297 PRLEAALASKDREILRLLKDVQHLQSSLQE---LEEASANQIADLERQLTAKSEAIEKLE 353
+ EA + + +L + LQ SL + L E+ A DL R L A+ E E
Sbjct: 711 TKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNR-LVAQLE-----E 764
Query: 354 EKLQAQSDYEEIKTELSILKAMKLASSTCSLPQGMAKP--EDSLLIAKEA 401
EK Q + + E ++ + + L Q +A+ E SL +A++A
Sbjct: 765 EKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQA 814
Score = 42.0 bits (97), Expect = 0.004
Identities = 61/255 (23%), Positives = 101/255 (39%), Gaps = 55/255 (21%)
Query: 163 RLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLH---SALKATQA 219
RL G+ + L E ++R+E E++ L +V TL L E +++ S +KA +
Sbjct: 1573 RLSGVQAELALQEESVRRSERERRATLDQVA-TLERSLQATESELRASQEKISKMKANET 1631
Query: 220 EL--------------------LELRRKY-------------DEEAASKA--DEVGLIMT 244
+L LEL+R+ D EA ++A D V +
Sbjct: 1632 KLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQR 1691
Query: 245 NLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQG------PSGDKVNFTLCSGPR 298
+ + +A Q VE L LA V S +G S +N T
Sbjct: 1692 QVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLH 1751
Query: 299 LEAALAS--KDREILR--------LLKDVQHLQSSLQELEEASANQIADLERQLTAKSEA 348
L+ AL + DR++L+ L + + SSL E + ++ADLE Q
Sbjct: 1752 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1811
Query: 349 IEKLEEKLQAQSDYE 363
+++L E L+ + + E
Sbjct: 1812 LQQLREVLRQRQEGE 1826
Score = 38.5 bits (88), Expect = 0.049
Identities = 96/436 (22%), Positives = 172/436 (39%), Gaps = 75/436 (17%)
Query: 19 RLQKELNSVASELSARQEESEHSHKHLIEL--RREFKKNVPEEIREMVA------PVLKS 70
RL++E + + + E E SH+ L +L +R E+RE ++ +L++
Sbjct: 642 RLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQA 701
Query: 71 FQAEVV-ALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRR 129
+AEV AL+K LS+ K E +L++ L Q +
Sbjct: 702 EKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESL--------AQDKL 753
Query: 130 DLHTSWKRNPELLSPKE--QREGTSPAGPTLTEGSRLP-----------GIPGKALLTET 176
DL+ + E S + QR+ A E RL G+ G + E
Sbjct: 754 DLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQ 813
Query: 177 LLQRNEAE------KQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDE 230
+ E + ++ LQE L+ +L E++ L A + Q ++ L R E
Sbjct: 814 AQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQE---LEQARREAQRQVEALERAARE 870
Query: 231 EAASKADEVGLIM----------------TNLEKANQRAEAAQREV-------ESLREQL 267
+ A + GL + T L + E + EV E+ REQL
Sbjct: 871 KEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQL 930
Query: 268 ASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDREIL--RLLKDVQHLQSSLQ 325
+ ++ LA + G + + + AS D+E++ +L++ + Q+SL+
Sbjct: 931 EAEGQALLLAKETLTGELAGLRQQIIATQEK-----ASLDKELMAQKLVQAEREAQASLR 985
Query: 326 ELEEASANQIADLERQLTAKSEAIEKLEEKLQA--QSDYEEIKTELSILKAMKLASSTCS 383
E A + L+R+ A +E +LQ+ Q + EE+ L K +L+ +
Sbjct: 986 EQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKE-ELSEEIAA 1044
Query: 384 LPQGMAKPEDSLLIAK 399
L Q + ++ LL+A+
Sbjct: 1045 LQQ---ERDEGLLLAE 1057
Score = 35.8 bits (81), Expect = 0.32
Identities = 88/418 (21%), Positives = 154/418 (36%), Gaps = 66/418 (15%)
Query: 18 RRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPE--EIREMVAPVLKSFQAEV 75
+R + EL + S L+ + E E R+ +K V E E R V L QAE+
Sbjct: 1522 QRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAEL 1581
Query: 76 ------VALSKRSQEAEAAFLSVYKQLIEAPDP-----------VPVFEAARSLDDRLQP 118
V S+R + A ++ ++ ++A + + E D R
Sbjct: 1582 ALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLK 1641
Query: 119 PSFDPSGQ-------PRRDLHTSWKRNPELLSPKEQR----------------EGTSPAG 155
D S RR L +R+ LS +E + + AG
Sbjct: 1642 EVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAG 1701
Query: 156 PTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALK 215
RL G K +E L+ +K +GL E +A L +K L AL
Sbjct: 1702 TLQLTVERLNGALAKVEESEGALR----DKVRGLTEALAQSSASLNSTRDKNLHLQKALT 1757
Query: 216 ATQAELLELRRKYD----------EEAASKADEVGLIMTNLEKANQRAEAAQREVESLRE 265
A + + L+ + D ++++S ++V + + + A+ +++ LRE
Sbjct: 1758 ACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLRE 1817
Query: 266 QLASVNSSIRLACCSPQGPSGDK--VNFTLCSGPRLEAALASKDREI----LRLLKDVQH 319
L A + Q ++ + L S R A L ++ RE+ LRL KD
Sbjct: 1818 VLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVA 1877
Query: 320 LQSSLQELEEASANQIADLERQLTAKSEAIEKLE----EKLQAQSDYEEIKTELSILK 373
L+ +L ++E D R K L E +AQ ++++ ++ +L+
Sbjct: 1878 LRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLE 1935
Score = 34.7 bits (78), Expect = 0.70
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 27/189 (14%)
Query: 178 LQRNEAEKQKGLQEVQITLAARL-GEAE--EKIKVLHSALKATQAELLELRRKYDEEAAS 234
LQR EAE Q LQ+++ L R GEA ++ L + Q L L+R + A
Sbjct: 1803 LQRVEAEGQ--LQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAE 1860
Query: 235 KADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLC 294
K EV LEK +VE RE+L S ++RL S +K
Sbjct: 1861 KR-EVERSALRLEKDRVALRRTLDKVE--REKLRSHEDTVRL--------SAEK------ 1903
Query: 295 SGPRLEAALASKDREILRLLKDVQHLQSSLQELEE--ASANQIADLERQLTAKSEAIEKL 352
RL+ L + E+ + +Q L++ + LE+ + A D ++Q + +E+L
Sbjct: 1904 --GRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1961
Query: 353 EEKLQAQSD 361
QAQ++
Sbjct: 1962 -RSAQAQTE 1969
Score = 31.6 bits (70), Expect = 6.0
Identities = 48/199 (24%), Positives = 73/199 (36%), Gaps = 27/199 (13%)
Query: 177 LLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKA 236
LL E LQE L L E+ L ++AE EL KY+ A S+
Sbjct: 67 LLPATEMASLLSLQEENQLLQQELSRVED-------LLAQSRAERDELAIKYN--AVSER 117
Query: 237 DEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSG 296
E L + E Q R+ LR QL +S R + Q G
Sbjct: 118 LEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQ------------EG 165
Query: 297 PRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKL 356
+ +A L + RL + + ELE+ + +LE+Q +E + LE L
Sbjct: 166 QQRQAQL------VQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESAL 219
Query: 357 QAQSDYEEIKTELSILKAM 375
+ ++ L+ + AM
Sbjct: 220 IRLEEEQQRSASLAQVNAM 238
Score = 31.6 bits (70), Expect = 6.0
Identities = 73/316 (23%), Positives = 126/316 (39%), Gaps = 46/316 (14%)
Query: 154 AGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQ--------KGLQEVQIT-------LAA 198
AG L+ G RL +A L + L + + E+Q K L + Q+ L+A
Sbjct: 338 AGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSA 397
Query: 199 RLGEAEEKIKVLHSA-LKATQA--------ELLELRRKYDEEAASKADEVGLIMTNLEKA 249
R+ E +K L L+ Q E LE R ++ A D GL T + A
Sbjct: 398 RVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLA 457
Query: 250 NQRAEAAQREVE-SLREQLASVNSSIRLACCSPQGPSGDKVNFT-LCSGPRLEAALASKD 307
++ V+ S E+ A ++ + PS + + PR + A D
Sbjct: 458 QAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSD 517
Query: 308 REILRLLKDVQHL-QSSLQELE---EASANQIADLERQLTAKSEAIEKLEEKLQ------ 357
L L+ H Q +Q++ EAS + + L +QL+ LEE+LQ
Sbjct: 518 SSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKT 577
Query: 358 --AQSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSL 415
A +E+ + E+ +L S+ L + + SL +A++ ++ E+ L
Sbjct: 578 DGAMQAHEDAQREV-----QRLRSANELLSREKSNLAHSLQVAQQ---QAEELRQEREKL 629
Query: 416 LASPEEDPSEDDSIKD 431
A+ EE + D +++
Sbjct: 630 QAAQEELRRQRDRLEE 645
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 58.9 bits (141), Expect = 3e-08
Identities = 78/276 (28%), Positives = 103/276 (37%), Gaps = 47/276 (17%)
Query: 1222 RMRREMLVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQSPDSETE-DQKPTV--KELELQ 1278
+ ++ L E +D P GGP P + D SP++ + KP V K EL
Sbjct: 239 QQHQQQLAEDAKDVP----GGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELA 294
Query: 1279 EGPEENSTPL-------TTQDKAQVRIKQEQMEEDAEEEAGSQPQDSGEL-----DKGQG 1326
P TP TT R + +E+ E+AGS +G L K +G
Sbjct: 295 SPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRG 354
Query: 1327 PPKEEHPDP-PGND--------GLPKVAPGPLLPGGSTPDCPSLHPQQESEAG--ERLHP 1375
PK P P D PK P P LP S+P PS +Q G E P
Sbjct: 355 TPKPSEGTPAPRKDPPWITLVQAEPKKKPAP-LPPSSSPGPPSQDSRQVENGGTEEVAQP 413
Query: 1376 DPLS------FKSASESSRCSLEVSLNSPSAASSPGL------MMSVSPVPSSSAPISPS 1423
P + + E E + +PS A+SP L S+ P + SP
Sbjct: 414 SPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPK 473
Query: 1424 PPGAPPAKVPSASPTADMAGALH----PSAKVNPNL 1455
P + PSASP A A L PSA +P L
Sbjct: 474 TKKRPAPRAPSASPLALHASRLSHSEPPSATPSPAL 509
Score = 51.2 bits (121), Expect = 7e-06
Identities = 66/224 (29%), Positives = 91/224 (40%), Gaps = 35/224 (15%)
Query: 1239 DPSGGPGILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQD-KAQVR 1297
+P P LPP S P P S DS + G EE + P T +++
Sbjct: 378 EPKKKPAPLPPSSS---PGPPSQDSRQVENG----------GTEEVAQPSPTASLESKPY 424
Query: 1298 IKQEQMEEDAEEEAGSQPQ--DSGELDKGQGPPKEEHP---DPPGNDGLPKVAPGPLLPG 1352
E+ EED EEEA + P S L + PK HP P + K P P P
Sbjct: 425 NPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPS 484
Query: 1353 GSTPDCPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSP 1412
S +LH + S H +P SA+ S S+E SL+S SA+ + G + P
Sbjct: 485 ASP---LALHASRLS------HSEP---PSATPSPALSVE-SLSSESASQTAGAELLEPP 531
Query: 1413 -VPSSSAPISPSPPGAP--PAKVPSASPTADMAGALHPSAKVNP 1453
VP SS+ + PG P P + + S A + P + P
Sbjct: 532 AVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMP 575
Score = 33.1 bits (74), Expect = 2.1
Identities = 68/344 (19%), Positives = 111/344 (32%), Gaps = 47/344 (13%)
Query: 437 QSYPSPQQLPPPPGPEDPL-SPSPGQPLLGPSLGPDGTRTFSLSPFPSLASGERLMMPPA 495
++ P P PG L SP G+P P + T +P P + + ++ A
Sbjct: 275 EARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQA 334
Query: 496 AFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGGGGGAAGPGAEEEQLDT 555
G L P P+P G P+P++ G P + +
Sbjct: 335 GSSSLVNGRL----------------HELPVPKPRGTPKPSE----GTPAPRKDPPWITL 374
Query: 556 AEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQF 615
+ + K L + + G E+ A+P P L K PF + ++
Sbjct: 375 VQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEV-AQPSPTASLESKPYNPFEEEEED 433
Query: 616 LSDEQNVL-ALRTIQVRQRGSITPRIRTPETGSDDAIKSILEQAKKEIESQKGGEPKTSV 674
+E +L T TP+ P G + + KK + ++
Sbjct: 434 KEEEAPAAPSLATSPALGHPESTPKSLHPWYG---ITPTSSPKTKKRPAPRAPSASPLAL 490
Query: 675 APLSIANGTTPASTSEDAIKSILEQARREMQAQQQALLEMEVAPRGRSVP----PSPPER 730
+++ P++T A+ + Q LLE P+ S P P P
Sbjct: 491 HASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGN 550
Query: 731 P-SLATASQ----------------NGAPALVKQEEGSGGPAQA 757
P SL+T S +P L + GS GP A
Sbjct: 551 PVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPA 594
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 58.5 bits (140), Expect = 5e-08
Identities = 70/235 (29%), Positives = 82/235 (34%), Gaps = 64/235 (27%)
Query: 375 MKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPEEDPSEDDSIKDSLG 434
++LA P +A P L + A FP Q SL SP P +
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 569
Query: 435 TEQSYPSPQQLP-------PP------------------PGPEDPLSPSPGQPLLGPSL- 468
Q PSP P PP PGP P S SP L GP L
Sbjct: 570 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 629
Query: 469 ------------------GPDGTRTFSLSPFPSLAS-----GERLMMPPAAFKGEAGGLL 505
GP+G S P LA+ R PP AF+G G L
Sbjct: 630 GHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 689
Query: 506 VFPPA-----------FYGAKPPTAPATPAPGP-EPLGGPEPADGGGGGAAGPGA 548
+PPA Y + P + ATPAPG +P GP P GG AAG GA
Sbjct: 690 PWPPATGPGSADGLCTIYETEGPES-ATPAPGALDP--GPSPGTSGGKAAAGAGA 741
Score = 41.6 bits (96), Expect = 0.006
Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 11/134 (8%)
Query: 1327 PPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHP--DPLSFKSAS 1384
PP + P PP + L +A P P+ ++H Q + P P S ++
Sbjct: 403 PPLQAPPSPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
Query: 1385 ESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMA-- 1442
S + S PS A+ P + V P P +S P+SPS P A P A+P +A
Sbjct: 459 PVSPSATPPSQAPPSLAAPP---LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
Query: 1443 GALHPSAKVNPNLQ 1456
P A P LQ
Sbjct: 516 PPQAPPALATPPLQ 529
Score = 37.7 bits (86), Expect = 0.083
Identities = 41/157 (26%), Positives = 52/157 (33%), Gaps = 47/157 (29%)
Query: 419 PEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPS---PGQ---PLLGPSL---- 468
P P + S P Q+PP P P+SPS P Q PL P L
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514
Query: 469 -GPDGTRTFSLSPFPSLASGERLMMPPAAFKGE-------------------------AG 502
P + P +L S PPA+F G+ A
Sbjct: 515 PPPQAPPALATPPLQALPS------PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Query: 503 GLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGG 539
LL PP+ PP +P AP P GP+ + G
Sbjct: 569 PLLQVPPS-----PPASPTLQAPRRPPTPGPDTSVSG 600
Score = 36.2 bits (82), Expect = 0.24
Identities = 45/169 (26%), Positives = 61/169 (36%), Gaps = 27/169 (15%)
Query: 1313 SQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPG--------GSTPDCPSLHPQ 1364
S P SG +G P HP P GL + P + P G P P
Sbjct: 250 SSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 1365 QESEAGERLHPD-PLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSP--VPSSSAPIS 1421
+ + P P + S+S + + + + L PS ++ P L SP P S A S
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 1422 -------------PSPPGAPPAKVPSASPTADMAGALH--PSAKVNPNL 1455
PSPP +P A P +P A L PS +P L
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417
Score = 36.2 bits (82), Expect = 0.24
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 29/213 (13%)
Query: 1240 PSGGPGI-LPPGHSHPDPT---PQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQ 1295
P P + LPP + P P P SP + Q P + L + P S P + +A
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF--SPPPSPPVQAP 451
Query: 1296 VRIKQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGL------PKVAPGPL 1349
+ P PP + P PP + + P AP PL
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLA------APPLQVPPSPPASPPMSPSATPPPQAPPPL 505
Query: 1350 L--PGGSTPDCPSLHPQQESEAGERLHPDPLSFKS-ASESSRCSLEVS-LNSPSAASSPG 1405
P P P + + L P SF A S SL +S L +P + P
Sbjct: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 1406 LMMSVSPVPSSSAPISPSPPGAPPAKVPSASPT 1438
L + VP PSPP +P + P PT
Sbjct: 566 LAAPLLQVP-------PSPPASPTLQAPRRPPT 591
Score = 35.4 bits (80), Expect = 0.41
Identities = 33/112 (29%), Positives = 38/112 (33%), Gaps = 5/112 (4%)
Query: 441 SPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSP----FPSLASGERLMMPPAA 496
+P PP P + P SP P P + PS P SL+ P M P A
Sbjct: 438 APFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496
Query: 497 FKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGGGGGAAGPGA 548
+A L PP PP AP A P PA G P A
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
Score = 34.3 bits (77), Expect = 0.92
Identities = 58/227 (25%), Positives = 81/227 (35%), Gaps = 13/227 (5%)
Query: 672 TSVAPLSI---ANGTT-PASTSEDAIKSILEQARREMQAQQQALLEMEVAPRGRSVPPSP 727
TS P+S A+GTT P + ++ E+ +A + A R
Sbjct: 109 TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
Query: 728 PERPSLATASQNGAPALVKQEEGSGGPAQAPLPVLSPAAFVQSIIRKVKSEIGDAGYFDH 787
P PS A A ++ A A+ P P V S +E A
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA---R 225
Query: 788 HWASDRGLLSRPYA-SVSPSLSSSSSSGYSGQPNGRAWPRGDEAPVPPED---EAAAGAE 843
S G L RP + S+S S + SS SG P+ R PR P P+ +A +
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSG-PSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 844 DEPPRTGELKAEGATAEAGARLPYYPAYVPRTLKPTVPPLTPEQYEL 890
PPR A G + + P A + PT+ P TP L
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL-PATPHSSSL 330
Score = 33.1 bits (74), Expect = 2.1
Identities = 53/184 (28%), Positives = 65/184 (35%), Gaps = 31/184 (16%)
Query: 378 ASSTCSL--------PQGMAKPEDSLLIAKEAFFPTQKFL-LEKPSLLASPEEDPSEDDS 428
+S TC L P A P L + A P+Q L P+L A+ PS S
Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387
Query: 429 IKDSLGTEQSYPSPQ-QLPPPPGPEDPLSPSPGQPLLGPS-LGPDGTRT------FSLSP 480
L T P LPP P P + P PL PS P+ FS P
Sbjct: 388 ---PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444
Query: 481 FPSLAS-----GERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAP-----ATPAP-GPEP 529
P + + + P A +A L PP PP +P ATP P P P
Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
Query: 530 LGGP 533
L P
Sbjct: 505 LAAP 508
Score = 31.6 bits (70), Expect = 6.0
Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 30/227 (13%)
Query: 1240 PSGGPGIL--PPGHSHPDPT---PQSPDSETEDQKP---TVKELELQEGPEENSTPLTTQ 1291
PS P L PP P P P SP + Q P L+L + P + L T
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526
Query: 1292 DKAQVRIKQEQMEEDAE-EEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLL 1350
+ A + S P Q PP P L +V P P
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LLQVPPSP-- 577
Query: 1351 PGGSTPDCPSLHPQ---QESEAGERLH----PDPLSFKSASESSRCS-LEVSLNSPSAAS 1402
P T P P S +G RL P P S S SS S +++ +S SA S
Sbjct: 578 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 637
Query: 1403 SPGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMAGALHPSA 1449
+P + P A SP P A++ + P A G P A
Sbjct: 638 TPEELRGYDSGPEGGAAASP----PPDAELAACHPAAWSRGPAPPLA 680
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 58.5 bits (140), Expect = 5e-08
Identities = 70/235 (29%), Positives = 82/235 (34%), Gaps = 64/235 (27%)
Query: 375 MKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPEEDPSEDDSIKDSLG 434
++LA P +A P L + A FP Q SL SP P +
Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530
Query: 435 TEQSYPSPQQLP-------PP------------------PGPEDPLSPSPGQPLLGPSL- 468
Q PSP P PP PGP P S SP L GP L
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 590
Query: 469 ------------------GPDGTRTFSLSPFPSLAS-----GERLMMPPAAFKGEAGGLL 505
GP+G S P LA+ R PP AF+G G L
Sbjct: 591 GHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 650
Query: 506 VFPPA-----------FYGAKPPTAPATPAPGP-EPLGGPEPADGGGGGAAGPGA 548
+PPA Y + P + ATPAPG +P GP P GG AAG GA
Sbjct: 651 PWPPATGPGSADGLCTIYETEGPES-ATPAPGALDP--GPSPGTSGGKAAAGAGA 702
Score = 41.6 bits (96), Expect = 0.006
Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 11/134 (8%)
Query: 1327 PPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHP--DPLSFKSAS 1384
PP + P PP + L +A P P+ ++H Q + P P S ++
Sbjct: 364 PPLQAPPSPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 1385 ESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMA-- 1442
S + S PS A+ P + V P P +S P+SPS P A P A+P +A
Sbjct: 420 PVSPSATPPSQAPPSLAAPP---LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476
Query: 1443 GALHPSAKVNPNLQ 1456
P A P LQ
Sbjct: 477 PPQAPPALATPPLQ 490
Score = 37.7 bits (86), Expect = 0.083
Identities = 41/157 (26%), Positives = 52/157 (33%), Gaps = 47/157 (29%)
Query: 419 PEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPS---PGQ---PLLGPSL---- 468
P P + S P Q+PP P P+SPS P Q PL P L
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475
Query: 469 -GPDGTRTFSLSPFPSLASGERLMMPPAAFKGE-------------------------AG 502
P + P +L S PPA+F G+ A
Sbjct: 476 PPPQAPPALATPPLQALPS------PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529
Query: 503 GLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGG 539
LL PP+ PP +P AP P GP+ + G
Sbjct: 530 PLLQVPPS-----PPASPTLQAPRRPPTPGPDTSVSG 561
Score = 37.4 bits (85), Expect = 0.11
Identities = 41/145 (28%), Positives = 55/145 (37%), Gaps = 9/145 (6%)
Query: 1313 SQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGER 1372
S P SG +G P HP P GL + P + P P+L P S
Sbjct: 241 SSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRKDA-APALGPLSSSPLAT- 297
Query: 1373 LHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPAKV 1432
P P + S S+ SL+ + P+ S SP ++ PSPP +P A
Sbjct: 298 --PSPSA--PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353
Query: 1433 PSASPTADMAGALH--PSAKVNPNL 1455
P +P A L PS +P L
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPL 378
Score = 36.2 bits (82), Expect = 0.24
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 29/213 (13%)
Query: 1240 PSGGPGI-LPPGHSHPDPT---PQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQ 1295
P P + LPP + P P P SP + Q P + L + P S P + +A
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF--SPPPSPPVQAP 412
Query: 1296 VRIKQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGL------PKVAPGPL 1349
+ P PP + P PP + + P AP PL
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLA------APPLQVPPSPPASPPMSPSATPPPQAPPPL 466
Query: 1350 L--PGGSTPDCPSLHPQQESEAGERLHPDPLSFKS-ASESSRCSLEVS-LNSPSAASSPG 1405
P P P + + L P SF A S SL +S L +P + P
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526
Query: 1406 LMMSVSPVPSSSAPISPSPPGAPPAKVPSASPT 1438
L + VP PSPP +P + P PT
Sbjct: 527 LAAPLLQVP-------PSPPASPTLQAPRRPPT 552
Score = 35.4 bits (80), Expect = 0.41
Identities = 33/112 (29%), Positives = 38/112 (33%), Gaps = 5/112 (4%)
Query: 441 SPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSP----FPSLASGERLMMPPAA 496
+P PP P + P SP P P + PS P SL+ P M P A
Sbjct: 399 APFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
Query: 497 FKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGGGGGAAGPGA 548
+A L PP PP AP A P PA G P A
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509
Score = 35.0 bits (79), Expect = 0.54
Identities = 52/207 (25%), Positives = 74/207 (35%), Gaps = 24/207 (11%)
Query: 1256 PTPQSPD-SETEDQKPTVKELEL-QEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGS 1313
PTP +P + + E+ L + P P T + V E + A
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 1314 QPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAG-ER 1372
+P G L + P + GP G TP P+ HP Q G +
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPA----RSGPSARG--TPRAPA-HPSQPKPKGLQA 270
Query: 1373 LHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPAKV 1432
L P ++ + + +L +SP A SP S PS SAP S +PPA
Sbjct: 271 LRPPQVT--PPRKDAAPALGPLSSSPLATPSP------SAPPSPSAPPSLQTLPSPPATP 322
Query: 1433 PS------ASPTADMAGALHPSAKVNP 1453
PS SPT + PS ++P
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSP 349
Score = 33.1 bits (74), Expect = 2.1
Identities = 58/238 (24%), Positives = 84/238 (35%), Gaps = 31/238 (13%)
Query: 1240 PSGGPGILPPGHSHPDPTP-QSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRI 1298
P+ G G P + P P SP + +P GP + ++ R
Sbjct: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRP---------GPLGQKGLRISAEETVARG 136
Query: 1299 KQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGND-GLPKVAPG-----PLLPG 1352
K + + + AG++ SG P G + GLP+ AP P
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 1353 GSTPDCPSLHPQQESEAGERLHPD-------PLSFKSASESSRCSLEVSLNSPSAASSPG 1405
+ S H E R P P S +S S S+ + + PSA +P
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARSGPSARGTPR 255
Query: 1406 LMMSVS-PVPSSSAPISP---SPP--GAPPAKVP-SASPTADMAGALHPSAKVNPNLQ 1456
S P P + P +PP A PA P S+SP A + + PS P+LQ
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313
Score = 33.1 bits (74), Expect = 2.1
Identities = 54/186 (29%), Positives = 68/186 (36%), Gaps = 24/186 (12%)
Query: 369 LSILKAMKLASSTCSLPQG-MAKPEDSLLIAKEAFFPTQKFL-LEKPSLLASPEEDPSED 426
L L + LA+ + S P A P L + A P+Q L P+L A+ PS
Sbjct: 287 LGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346
Query: 427 DSIKDSLGTEQSYPSPQ-QLPPPPGPEDPLSPSPGQPLLGPS-LGPDGTRT------FSL 478
S L T P LPP P P + P PL PS P+ FS
Sbjct: 347 LS---PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 403
Query: 479 SPFPSLAS-----GERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAP-----ATPAP-GP 527
P P + + + P A +A L PP PP +P ATP P P
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Query: 528 EPLGGP 533
PL P
Sbjct: 464 PPLAAP 469
Score = 32.0 bits (71), Expect = 4.6
Identities = 57/227 (25%), Positives = 81/227 (35%), Gaps = 17/227 (7%)
Query: 672 TSVAPLSI---ANGTT-PASTSEDAIKSILEQARREMQAQQQALLEMEVAPRGRSVPPSP 727
TS P+S A+GTT P + ++ E+ +A + A R
Sbjct: 100 TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 159
Query: 728 PERPSLATASQNGAPALVKQEEGSGGPAQAPLPVLSPAAFVQSIIRKVKSEIGDAGYFDH 787
P PS A A ++ A A+ P P V S +E A
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA---R 216
Query: 788 HWASDRGLLSRPYA-SVSPSLSSSSSSGYSGQPNGRAWPRGDEAPVPPED---EAAAGAE 843
S G L RP + S+S S + SS SG P+ R PR P P+ +A +
Sbjct: 217 RRPSAGGGLQRPASRSLSSSATPLSSPARSG-PSARGTPRAPAHPSQPKPKGLQALRPPQ 275
Query: 844 DEPPRTGELKAEGATAEAGARLPYYPAYVPRTLKPTV-----PPLTP 885
PPR A G + + P A + P++ PP TP
Sbjct: 276 VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATP 322
Score = 31.6 bits (70), Expect = 6.0
Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 30/227 (13%)
Query: 1240 PSGGPGIL--PPGHSHPDPT---PQSPDSETEDQKP---TVKELELQEGPEENSTPLTTQ 1291
PS P L PP P P P SP + Q P L+L + P + L T
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487
Query: 1292 DKAQVRIKQEQMEEDAE-EEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLL 1350
+ A + S P Q PP P L +V P P
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LLQVPPSP-- 538
Query: 1351 PGGSTPDCPSLHPQ---QESEAGERLH----PDPLSFKSASESSRCS-LEVSLNSPSAAS 1402
P T P P S +G RL P P S S SS S +++ +S SA S
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 598
Query: 1403 SPGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMAGALHPSA 1449
+P + P A SP P A++ + P A G P A
Sbjct: 599 TPEELRGYDSGPEGGAAASP----PPDAELAACHPAAWSRGPAPPLA 641
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 58.5 bits (140), Expect = 5e-08
Identities = 87/377 (23%), Positives = 168/377 (44%), Gaps = 44/377 (11%)
Query: 19 RLQKELNSVASELSARQEESEHSHKHLIELRR---EFKKNVPEEIREMVAPVLK--SFQA 73
+L+KEL++ + +E++E L +L + + N P+E E++ VL+ + +
Sbjct: 361 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ 420
Query: 74 EVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHT 133
E L+ + + +A +E + + A+ L +R F+ Q L T
Sbjct: 421 EAATLAANNTQLQAR--------VEMLETERGQQEAKLLAER---GHFEEEKQQLSSLIT 469
Query: 134 SWKRNPELLSP-KEQREGTSPA-GPTLTEGSRLPGIPGKALLTETLLQRNEAE----KQK 187
+ + LS KE+ E S A G LT +++ + + +Q+ + E KQ+
Sbjct: 470 DLQSSISNLSQAKEELEQASQAHGARLT--AQVASLTSELTTLNATIQQQDQELAGLKQQ 527
Query: 188 GLQEVQITLAARLGEAEE-------KIKVLHSALKATQAELLELRRKYDEEAASKADEVG 240
+E Q LA L + E+ +++ L S+LK + +L E+ K + A ++
Sbjct: 528 A-KEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLA 586
Query: 241 LIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLE 300
E + + +AA +++E+L ++ A+ I + D ++ R +
Sbjct: 587 TAAEEREASLRERDAALKQLEALEKEKAA-KLEILQQQLQVANEARDSAQTSVTQAQREK 645
Query: 301 AALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSE-AIEK---LEEKL 356
A L+ K E+ + +++ QE EA A Q+A+LE QL ++ + A EK +EK
Sbjct: 646 AELSRKVEELQACV------ETARQEQHEAQA-QVAELELQLRSEQQKATEKERVAQEKD 698
Query: 357 QAQSDYEEIKTELSILK 373
Q Q + +K L + K
Sbjct: 699 QLQEQLQALKESLKVTK 715
Score = 51.2 bits (121), Expect = 7e-06
Identities = 99/439 (22%), Positives = 183/439 (41%), Gaps = 45/439 (10%)
Query: 3 ANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIRE 62
A G+MFQ L L++E EL +E+ H EL+ ++N E+
Sbjct: 825 AQYGAMFQE----QLMTLKEECEKARQELQEAKEKVAGIESHS-ELQISRQQNELAELHA 879
Query: 63 MVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEA-ARSLDDRLQPPSF 121
+A L+ Q + V R+Q+ ++ +++ V E R ++ + S
Sbjct: 880 NLARALQQVQEKEV----RAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASR 935
Query: 122 DPSGQPRRDLHTSWKRNPELLSPKEQRE--GTSPAGPTLTEGSRLPGIPGKALLTETLLQ 179
+ +P R + R PE L ++ R+ T A + + G + L +
Sbjct: 936 ELVKEPAR----AGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMES 991
Query: 180 RNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAEL-LELRRKYDE---EAASK 235
+ + ++++G QE ++ ARL + + + + KA +AEL + L+ +E E A+
Sbjct: 992 QGQQQEERGQQEREV---ARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATL 1048
Query: 236 ADEVGLIMTNLEKANQRA------EAAQ-REVESLREQLASVNSSI---RLACCSPQGPS 285
+ + +T E +Q EAAQ +E+E LR+ + + + S G
Sbjct: 1049 QEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQ 1108
Query: 286 GDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAK 345
+ T +GP+LEA A E+ +L + Q Q LE + + A + +A
Sbjct: 1109 SEAAGRTEPTGPKLEALRA----EVSKLEQQCQKQQEQADSLERSLEAERASRAERDSAL 1164
Query: 346 SEAIEKLEEKLQAQSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPT 405
+LEEK Q E ++ ++ A + ++ + Q +K ED K
Sbjct: 1165 ETLQGQLEEKAQ-----ELGHSQSALASAQRELAAFRTKVQDHSKAEDEW---KAQVARG 1216
Query: 406 QKFLLEKPSLLASPEEDPS 424
++ K SL++S EE+ S
Sbjct: 1217 RQEAERKNSLISSLEEEVS 1235
Score = 38.9 bits (89), Expect = 0.037
Identities = 60/255 (23%), Positives = 109/255 (42%), Gaps = 35/255 (13%)
Query: 180 RNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKY--DEEAASKAD 237
R EAE++ L + EE++ +L+ + + E EL+R + E + K +
Sbjct: 1217 RQEAERKNSL----------ISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLE 1266
Query: 238 EVGLIM-----TNLEKANQRAEAAQREVESLREQ-----LASVNSSIRLACCSPQGPSGD 287
E ++ +N +A +R+ A + EV+SLRE+ +AS N L + Q +
Sbjct: 1267 ERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQEL---TSQAERAE 1323
Query: 288 KVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSE 347
++ L + K++ + L + Q+ + EL A L +QL A+
Sbjct: 1324 ELGQEL---KAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAK-----HLCQQLQAEQA 1375
Query: 348 AIEKLEEKLQAQSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSL--LIAKEAFFPT 405
A EK + QS +L+A + L Q +A+ E + L A++A +
Sbjct: 1376 AAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAE 1435
Query: 406 QKFLLEKPSLLASPE 420
Q +L+K L + E
Sbjct: 1436 QLSMLKKAHGLLAEE 1450
Score = 37.0 bits (84), Expect = 0.14
Identities = 97/454 (21%), Positives = 179/454 (39%), Gaps = 71/454 (15%)
Query: 27 VASELSARQEESEHSHKHLIE--------LRREFKKNVPEEIREMVAPVLKSFQAEVVAL 78
+ +L A Q +E H+ +E LR E + E+ E++ K + E A
Sbjct: 1366 LCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLR-AQRELGELIPLRQKVAEQERTAQ 1424
Query: 79 SKRSQEAE-AAFLSVYKQL--IEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHTSW 135
R+++A A LS+ K+ + A + + E A +L + D + + +
Sbjct: 1425 QLRAEKASYAEQLSMLKKAHGLLAEENRGLGERA-NLGRQFLEVELDQAREKYVQELAAV 1483
Query: 136 KRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQI- 194
+ + E + QRE S A ++ G K L Q + ++++++
Sbjct: 1484 RADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVF 1543
Query: 195 ---------TLAARLGEAEEKIKVLHSALKATQA-------ELLELRRKYDE---EAASK 235
L+ +L ++++ KV LKA QA E L+ + +E + + K
Sbjct: 1544 QREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQK 1603
Query: 236 ADEVGLIMTNLEKANQRAEAAQREVESLREQLASV------NSSIRLACCSPQGPSGDKV 289
+EKA +A +++ + L+EQL S+ N +R +++
Sbjct: 1604 EQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELR--------AEAERL 1655
Query: 290 NFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASAN---QIADLERQLTAKS 346
L +A L +K+ E + +HL + ++ LE A+ Q+ DL + A +
Sbjct: 1656 GHEL-----QQAGLKTKEAE-----QTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVA-T 1704
Query: 347 EAIEKLEEKLQAQSDYEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQ 406
+A++ E + + Q D +LS + L S T LP+ D + E P
Sbjct: 1705 DALKSREPQAKPQLDLSIDSLDLSCEEGTPL-SITSKLPR---TQPDGTSVPGEPASPIS 1760
Query: 407 KFLLEKPSLLAS------PEEDPSEDDSIKDSLG 434
+ L K L S P + +S DSLG
Sbjct: 1761 QRLPPKVESLESLYFTPIPARSQAPLESSLDSLG 1794
Score = 32.0 bits (71), Expect = 4.6
Identities = 60/280 (21%), Positives = 109/280 (38%), Gaps = 39/280 (13%)
Query: 16 DLRRLQKELNSVASELSARQEESEHSHKHLIELRREF--KKNVPEEIREMVAPV------ 67
+ +RLQ +LN + ++LS +++ +EH + + + + KK +E++E + +
Sbjct: 1585 EAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKE 1644
Query: 68 LKSFQAEVVALSKRSQEA--------------EAAFLSVYKQLIEAPDPVPVFEAARSLD 113
K +AE L Q+A A S+ Q+ A + +
Sbjct: 1645 NKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVAT 1704
Query: 114 DRLQPPSFDPSGQPRRDLH------TSWKRNPELLS---PKEQREGTS-PAGPTLTEGSR 163
D L+ S +P +P+ DL + + P ++ P+ Q +GTS P P R
Sbjct: 1705 DALK--SREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQR 1762
Query: 164 LPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLE 223
LP P L A Q L+ +L ++ K + + + TQ +
Sbjct: 1763 LP--PKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTR--SARRRTTQIINIT 1818
Query: 224 LRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVESL 263
+ +K D E A+ T A+Q + A +SL
Sbjct: 1819 MTKKLDVEEPDSANS-SFYSTRSAPASQASLRATSSTQSL 1857
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 57.8 bits (138), Expect = 8e-08
Identities = 83/391 (21%), Positives = 174/391 (44%), Gaps = 34/391 (8%)
Query: 13 KRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQ 72
K +L +L+ + S+ SEL R ++ E S + L +L+R+ + + + E +A +
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA-SDFHEQIADLQAQIA 1079
Query: 73 AEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFD-PSGQPRRDL 131
+ L+K+ +E +AA + ++ + + + R L+ + D S + R+
Sbjct: 1080 ELKMQLAKKEEELQAALARLDDEIAQKNN---ALKKIRELEGHISDLQEDLDSERAARNK 1136
Query: 132 HTSWKRN--PELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGL 189
KR+ EL + K + E T + T E + K T+L++ E+ +
Sbjct: 1137 AEKQKRDLGEELEALKTELEDTLDSTATQQE------LRAKREQEVTVLKKALDEETRSH 1190
Query: 190 QEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
+ + + +A E++ K +A L + ++ ++E A A E+ + L +A
Sbjct: 1191 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV----LGQA 1246
Query: 250 NQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
Q E ++++E+ ++L S S A + DKV+ + L + +
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERA----RAELNDKVHKLQNEVESVTGMLNEAEGK 1302
Query: 310 ILRLLKDVQHLQSSLQELEEASANQ------IADLERQLTAKSEAI-EKLEEKLQAQSDY 362
++L KDV L S LQ+ +E + ++ RQL + ++ ++L+E+++A+ +
Sbjct: 1303 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
Query: 363 EEIKTELSI------LKAMKLASSTCSLPQG 387
E + L+I K AS+ +L +G
Sbjct: 1363 ERHISTLNIQLSDSKKKLQDFASTVEALEEG 1393
Score = 46.2 bits (108), Expect = 2e-04
Identities = 99/443 (22%), Positives = 182/443 (41%), Gaps = 87/443 (19%)
Query: 17 LRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPV------LKS 70
LR+L++E NS+ +L E ++ +H+ L + + +++++ + V K
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS-KKKLQDFASTVEALEEGKKR 1396
Query: 71 FQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRD 130
FQ E+ L+++ +E AA+ + K +RLQ Q D
Sbjct: 1397 FQKEIENLTQQYEEKAAAYDKLEKT-----------------KNRLQ--------QELDD 1431
Query: 131 LHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQ 190
L +L+S E+++ L E K + ++ +R+ AE + +
Sbjct: 1432 LVVDLDNQRQLVSNLEKKQ--RKFDQLLAEE--------KNISSKYADERDRAEAEAREK 1481
Query: 191 EVQ-ITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
E + ++LA L EA E + L K +AE+ E+ S D+VG + LEK+
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEM--------EDLVSSKDDVGKNVHELEKS 1533
Query: 250 NQRAEAAQREVESLREQL-----ASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALA 304
+ E E+++ E+L A+ ++ +RL +VN G + E L
Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDAKLRL-----------EVNMQALKG-QFERDLQ 1581
Query: 305 SKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLE---EKLQAQSD 361
++D + + + LQ L E E ++ D +Q + A +KLE + L+ Q+D
Sbjct: 1582 ARDEQ---NEEKRRQLQRQLHEYE----TELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Query: 362 -----YEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKF---LLEKP 413
EE +L L+A ++ L A ++ AKE + L++
Sbjct: 1635 SAIKGREEAIKQLRKLQA-QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1693
Query: 414 SLLASPEEDPSEDDSIKDSLGTE 436
LA+ E + D K+ L E
Sbjct: 1694 EDLAAAERARKQADLEKEELAEE 1716
Score = 44.7 bits (104), Expect = 7e-04
Identities = 75/374 (20%), Positives = 148/374 (39%), Gaps = 32/374 (8%)
Query: 30 ELSARQEESEHSHKHLIELRREFKKNVPEEIRE--MVAPVLKSFQAEVVALSKRSQEAEA 87
+L AR E++E + L E++ + +E ++ + A K + ++ L ++ A
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
Query: 88 AFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHTSWKRNPELLSPKEQ 147
KQL + + F+ R L+D + R ++ + K N + E
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQ--RELED---------ARASRDEIFATAKENEKKAKSLEA 1687
Query: 148 REGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKI 207
E +R K L E L + + LQ+ + L AR+ + EE++
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELA--SSLSGRNALQDEKRRLEARIAQLEEEL 1745
Query: 208 KVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVES-LREQ 266
+ ++A + + ++ ++ + A E N E A Q+ E +E+ S L E
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN-ESARQQLERQNKELRSKLHEM 1804
Query: 267 LASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALAS------KDREILRLLKDVQHL 320
+V S + + + +AA S K +EIL ++D + +
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864
Query: 321 QSSLQELEEASANQIADLERQLTAKSEAIEKL---EEKLQAQSD-----YEEIKTELSIL 372
+E E ++ L+RQL E +++ KLQ + D E + E++ L
Sbjct: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Query: 373 KA-MKLASSTCSLP 385
K+ ++ + T +P
Sbjct: 1925 KSKLRRGNETSFVP 1938
Score = 42.7 bits (99), Expect = 0.003
Identities = 47/221 (21%), Positives = 102/221 (46%), Gaps = 39/221 (17%)
Query: 183 AEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLI 242
A K++ L+E+ + ARL E E++ + L + K ++L+L + +EE A++
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR------- 966
Query: 243 MTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAA 302
+K A+ +++ L +++ + D N L +L
Sbjct: 967 ----QKLQLEKVTAEAKIKKLEDEILVM----------------DDQNNKLSKERKL--- 1003
Query: 303 LASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEA---IEKLEEKLQAQ 359
L + ++ L + + +L +L+ + I++LE +L + ++ +EKL+ KL+
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 360 -SDYEE----IKTELSILKAMKLASSTCSLPQGMAKPEDSL 395
SD+ E ++ +++ LK M+LA L +A+ +D +
Sbjct: 1064 ASDFHEQIADLQAQIAELK-MQLAKKEEELQAALARLDDEI 1103
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 57.8 bits (138), Expect = 8e-08
Identities = 83/391 (21%), Positives = 174/391 (44%), Gaps = 34/391 (8%)
Query: 13 KRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQ 72
K +L +L+ + S+ SEL R ++ E S + L +L+R+ + + + E +A +
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA-SDFHEQIADLQAQIA 1086
Query: 73 AEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFD-PSGQPRRDL 131
+ L+K+ +E +AA + ++ + + + R L+ + D S + R+
Sbjct: 1087 ELKMQLAKKEEELQAALARLDDEIAQKNN---ALKKIRELEGHISDLQEDLDSERAARNK 1143
Query: 132 HTSWKRN--PELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGL 189
KR+ EL + K + E T + T E + K T+L++ E+ +
Sbjct: 1144 AEKQKRDLGEELEALKTELEDTLDSTATQQE------LRAKREQEVTVLKKALDEETRSH 1197
Query: 190 QEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
+ + + +A E++ K +A L + ++ ++E A A E+ + L +A
Sbjct: 1198 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV----LGQA 1253
Query: 250 NQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
Q E ++++E+ ++L S S A + DKV+ + L + +
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERA----RAELNDKVHKLQNEVESVTGMLNEAEGK 1309
Query: 310 ILRLLKDVQHLQSSLQELEEASANQ------IADLERQLTAKSEAI-EKLEEKLQAQSDY 362
++L KDV L S LQ+ +E + ++ RQL + ++ ++L+E+++A+ +
Sbjct: 1310 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1369
Query: 363 EEIKTELSI------LKAMKLASSTCSLPQG 387
E + L+I K AS+ +L +G
Sbjct: 1370 ERHISTLNIQLSDSKKKLQDFASTVEALEEG 1400
Score = 46.2 bits (108), Expect = 2e-04
Identities = 99/443 (22%), Positives = 182/443 (41%), Gaps = 87/443 (19%)
Query: 17 LRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPV------LKS 70
LR+L++E NS+ +L E ++ +H+ L + + +++++ + V K
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS-KKKLQDFASTVEALEEGKKR 1403
Query: 71 FQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRD 130
FQ E+ L+++ +E AA+ + K +RLQ Q D
Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKT-----------------KNRLQ--------QELDD 1438
Query: 131 LHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQ 190
L +L+S E+++ L E K + ++ +R+ AE + +
Sbjct: 1439 LVVDLDNQRQLVSNLEKKQ--RKFDQLLAEE--------KNISSKYADERDRAEAEAREK 1488
Query: 191 EVQ-ITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
E + ++LA L EA E + L K +AE+ E+ S D+VG + LEK+
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEM--------EDLVSSKDDVGKNVHELEKS 1540
Query: 250 NQRAEAAQREVESLREQL-----ASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALA 304
+ E E+++ E+L A+ ++ +RL +VN G + E L
Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDAKLRL-----------EVNMQALKG-QFERDLQ 1588
Query: 305 SKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLE---EKLQAQSD 361
++D + + + LQ L E E ++ D +Q + A +KLE + L+ Q+D
Sbjct: 1589 ARDEQ---NEEKRRQLQRQLHEYE----TELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 362 -----YEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKF---LLEKP 413
EE +L L+A ++ L A ++ AKE + L++
Sbjct: 1642 SAIKGREEAIKQLRKLQA-QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700
Query: 414 SLLASPEEDPSEDDSIKDSLGTE 436
LA+ E + D K+ L E
Sbjct: 1701 EDLAAAERARKQADLEKEELAEE 1723
Score = 44.7 bits (104), Expect = 7e-04
Identities = 75/374 (20%), Positives = 148/374 (39%), Gaps = 32/374 (8%)
Query: 30 ELSARQEESEHSHKHLIELRREFKKNVPEEIRE--MVAPVLKSFQAEVVALSKRSQEAEA 87
+L AR E++E + L E++ + +E ++ + A K + ++ L ++ A
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645
Query: 88 AFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHTSWKRNPELLSPKEQ 147
KQL + + F+ R L+D + R ++ + K N + E
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQ--RELED---------ARASRDEIFATAKENEKKAKSLEA 1694
Query: 148 REGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKI 207
E +R K L E L + + LQ+ + L AR+ + EE++
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELA--SSLSGRNALQDEKRRLEARIAQLEEEL 1752
Query: 208 KVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVES-LREQ 266
+ ++A + + ++ ++ + A E N E A Q+ E +E+ S L E
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN-ESARQQLERQNKELRSKLHEM 1811
Query: 267 LASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALAS------KDREILRLLKDVQHL 320
+V S + + + +AA S K +EIL ++D + +
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1871
Query: 321 QSSLQELEEASANQIADLERQLTAKSEAIEKL---EEKLQAQSD-----YEEIKTELSIL 372
+E E ++ L+RQL E +++ KLQ + D E + E++ L
Sbjct: 1872 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1931
Query: 373 KA-MKLASSTCSLP 385
K+ ++ + T +P
Sbjct: 1932 KSKLRRGNETSFVP 1945
Score = 42.7 bits (99), Expect = 0.003
Identities = 47/221 (21%), Positives = 102/221 (46%), Gaps = 39/221 (17%)
Query: 183 AEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLI 242
A K++ L+E+ + ARL E E++ + L + K ++L+L + +EE A++
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR------- 973
Query: 243 MTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAA 302
+K A+ +++ L +++ + D N L +L
Sbjct: 974 ----QKLQLEKVTAEAKIKKLEDEILVM----------------DDQNNKLSKERKL--- 1010
Query: 303 LASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEA---IEKLEEKLQAQ 359
L + ++ L + + +L +L+ + I++LE +L + ++ +EKL+ KL+
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
Query: 360 -SDYEE----IKTELSILKAMKLASSTCSLPQGMAKPEDSL 395
SD+ E ++ +++ LK M+LA L +A+ +D +
Sbjct: 1071 ASDFHEQIADLQAQIAELK-MQLAKKEEELQAALARLDDEI 1110
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 57.8 bits (138), Expect = 8e-08
Identities = 83/391 (21%), Positives = 174/391 (44%), Gaps = 34/391 (8%)
Query: 13 KRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQ 72
K +L +L+ + S+ SEL R ++ E S + L +L+R+ + + + E +A +
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA-SDFHEQIADLQAQIA 1086
Query: 73 AEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFD-PSGQPRRDL 131
+ L+K+ +E +AA + ++ + + + R L+ + D S + R+
Sbjct: 1087 ELKMQLAKKEEELQAALARLDDEIAQKNN---ALKKIRELEGHISDLQEDLDSERAARNK 1143
Query: 132 HTSWKRN--PELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGL 189
KR+ EL + K + E T + T E + K T+L++ E+ +
Sbjct: 1144 AEKQKRDLGEELEALKTELEDTLDSTATQQE------LRAKREQEVTVLKKALDEETRSH 1197
Query: 190 QEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
+ + + +A E++ K +A L + ++ ++E A A E+ + L +A
Sbjct: 1198 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV----LGQA 1253
Query: 250 NQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
Q E ++++E+ ++L S S A + DKV+ + L + +
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERA----RAELNDKVHKLQNEVESVTGMLNEAEGK 1309
Query: 310 ILRLLKDVQHLQSSLQELEEASANQ------IADLERQLTAKSEAI-EKLEEKLQAQSDY 362
++L KDV L S LQ+ +E + ++ RQL + ++ ++L+E+++A+ +
Sbjct: 1310 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1369
Query: 363 EEIKTELSI------LKAMKLASSTCSLPQG 387
E + L+I K AS+ +L +G
Sbjct: 1370 ERHISTLNIQLSDSKKKLQDFASTVEALEEG 1400
Score = 46.2 bits (108), Expect = 2e-04
Identities = 99/443 (22%), Positives = 182/443 (41%), Gaps = 87/443 (19%)
Query: 17 LRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPV------LKS 70
LR+L++E NS+ +L E ++ +H+ L + + +++++ + V K
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS-KKKLQDFASTVEALEEGKKR 1403
Query: 71 FQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRD 130
FQ E+ L+++ +E AA+ + K +RLQ Q D
Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKT-----------------KNRLQ--------QELDD 1438
Query: 131 LHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQ 190
L +L+S E+++ L E K + ++ +R+ AE + +
Sbjct: 1439 LVVDLDNQRQLVSNLEKKQ--RKFDQLLAEE--------KNISSKYADERDRAEAEAREK 1488
Query: 191 EVQ-ITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
E + ++LA L EA E + L K +AE+ E+ S D+VG + LEK+
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEM--------EDLVSSKDDVGKNVHELEKS 1540
Query: 250 NQRAEAAQREVESLREQL-----ASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALA 304
+ E E+++ E+L A+ ++ +RL +VN G + E L
Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDAKLRL-----------EVNMQALKG-QFERDLQ 1588
Query: 305 SKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLE---EKLQAQSD 361
++D + + + LQ L E E ++ D +Q + A +KLE + L+ Q+D
Sbjct: 1589 ARDEQ---NEEKRRQLQRQLHEYE----TELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 362 -----YEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKF---LLEKP 413
EE +L L+A ++ L A ++ AKE + L++
Sbjct: 1642 SAIKGREEAIKQLRKLQA-QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700
Query: 414 SLLASPEEDPSEDDSIKDSLGTE 436
LA+ E + D K+ L E
Sbjct: 1701 EDLAAAERARKQADLEKEELAEE 1723
Score = 44.3 bits (103), Expect = 9e-04
Identities = 69/344 (20%), Positives = 134/344 (38%), Gaps = 26/344 (7%)
Query: 30 ELSARQEESEHSHKHLIELRREFKKNVPEEIRE--MVAPVLKSFQAEVVALSKRSQEAEA 87
+L AR E++E + L E++ + +E ++ + A K + ++ L ++ A
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645
Query: 88 AFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHTSWKRNPELLSPKEQ 147
KQL + + F+ R L+D + R ++ + K N + E
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQ--RELED---------ARASRDEIFATAKENEKKAKSLEA 1694
Query: 148 REGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKI 207
E +R K L E L + + LQ+ + L AR+ + EE++
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELA--SSLSGRNALQDEKRRLEARIAQLEEEL 1752
Query: 208 KVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVES-LREQ 266
+ ++A + + ++ ++ + A E N E A Q+ E +E+ S L E
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN-ESARQQLERQNKELRSKLHEM 1811
Query: 267 LASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALAS------KDREILRLLKDVQHL 320
+V S + + + +AA S K +EIL ++D + +
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1871
Query: 321 QSSLQELEEASANQIADLERQLTAKSEAIEKL---EEKLQAQSD 361
+E E ++ L+RQL E +++ KLQ + D
Sbjct: 1872 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1915
Score = 42.7 bits (99), Expect = 0.003
Identities = 47/221 (21%), Positives = 102/221 (46%), Gaps = 39/221 (17%)
Query: 183 AEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLI 242
A K++ L+E+ + ARL E E++ + L + K ++L+L + +EE A++
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR------- 973
Query: 243 MTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAA 302
+K A+ +++ L +++ + D N L +L
Sbjct: 974 ----QKLQLEKVTAEAKIKKLEDEILVM----------------DDQNNKLSKERKL--- 1010
Query: 303 LASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEA---IEKLEEKLQAQ 359
L + ++ L + + +L +L+ + I++LE +L + ++ +EKL+ KL+
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
Query: 360 -SDYEE----IKTELSILKAMKLASSTCSLPQGMAKPEDSL 395
SD+ E ++ +++ LK M+LA L +A+ +D +
Sbjct: 1071 ASDFHEQIADLQAQIAELK-MQLAKKEEELQAALARLDDEI 1110
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 57.8 bits (138), Expect = 8e-08
Identities = 83/391 (21%), Positives = 174/391 (44%), Gaps = 34/391 (8%)
Query: 13 KRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQ 72
K +L +L+ + S+ SEL R ++ E S + L +L+R+ + + + E +A +
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA-SDFHEQIADLQAQIA 1079
Query: 73 AEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFD-PSGQPRRDL 131
+ L+K+ +E +AA + ++ + + + R L+ + D S + R+
Sbjct: 1080 ELKMQLAKKEEELQAALARLDDEIAQKNN---ALKKIRELEGHISDLQEDLDSERAARNK 1136
Query: 132 HTSWKRN--PELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGL 189
KR+ EL + K + E T + T E + K T+L++ E+ +
Sbjct: 1137 AEKQKRDLGEELEALKTELEDTLDSTATQQE------LRAKREQEVTVLKKALDEETRSH 1190
Query: 190 QEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
+ + + +A E++ K +A L + ++ ++E A A E+ + L +A
Sbjct: 1191 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV----LGQA 1246
Query: 250 NQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
Q E ++++E+ ++L S S A + DKV+ + L + +
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERA----RAELNDKVHKLQNEVESVTGMLNEAEGK 1302
Query: 310 ILRLLKDVQHLQSSLQELEEASANQ------IADLERQLTAKSEAI-EKLEEKLQAQSDY 362
++L KDV L S LQ+ +E + ++ RQL + ++ ++L+E+++A+ +
Sbjct: 1303 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
Query: 363 EEIKTELSI------LKAMKLASSTCSLPQG 387
E + L+I K AS+ +L +G
Sbjct: 1363 ERHISTLNIQLSDSKKKLQDFASTVEALEEG 1393
Score = 46.2 bits (108), Expect = 2e-04
Identities = 99/443 (22%), Positives = 182/443 (41%), Gaps = 87/443 (19%)
Query: 17 LRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPV------LKS 70
LR+L++E NS+ +L E ++ +H+ L + + +++++ + V K
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS-KKKLQDFASTVEALEEGKKR 1396
Query: 71 FQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRD 130
FQ E+ L+++ +E AA+ + K +RLQ Q D
Sbjct: 1397 FQKEIENLTQQYEEKAAAYDKLEKT-----------------KNRLQ--------QELDD 1431
Query: 131 LHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQ 190
L +L+S E+++ L E K + ++ +R+ AE + +
Sbjct: 1432 LVVDLDNQRQLVSNLEKKQ--RKFDQLLAEE--------KNISSKYADERDRAEAEAREK 1481
Query: 191 EVQ-ITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
E + ++LA L EA E + L K +AE+ E+ S D+VG + LEK+
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEM--------EDLVSSKDDVGKNVHELEKS 1533
Query: 250 NQRAEAAQREVESLREQL-----ASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALA 304
+ E E+++ E+L A+ ++ +RL +VN G + E L
Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDAKLRL-----------EVNMQALKG-QFERDLQ 1581
Query: 305 SKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLE---EKLQAQSD 361
++D + + + LQ L E E ++ D +Q + A +KLE + L+ Q+D
Sbjct: 1582 ARDEQ---NEEKRRQLQRQLHEYE----TELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Query: 362 -----YEEIKTELSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKF---LLEKP 413
EE +L L+A ++ L A ++ AKE + L++
Sbjct: 1635 SAIKGREEAIKQLRKLQA-QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1693
Query: 414 SLLASPEEDPSEDDSIKDSLGTE 436
LA+ E + D K+ L E
Sbjct: 1694 EDLAAAERARKQADLEKEELAEE 1716
Score = 44.3 bits (103), Expect = 9e-04
Identities = 69/344 (20%), Positives = 134/344 (38%), Gaps = 26/344 (7%)
Query: 30 ELSARQEESEHSHKHLIELRREFKKNVPEEIRE--MVAPVLKSFQAEVVALSKRSQEAEA 87
+L AR E++E + L E++ + +E ++ + A K + ++ L ++ A
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
Query: 88 AFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHTSWKRNPELLSPKEQ 147
KQL + + F+ R L+D + R ++ + K N + E
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQ--RELED---------ARASRDEIFATAKENEKKAKSLEA 1687
Query: 148 REGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGEAEEKI 207
E +R K L E L + + LQ+ + L AR+ + EE++
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELA--SSLSGRNALQDEKRRLEARIAQLEEEL 1745
Query: 208 KVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVES-LREQ 266
+ ++A + + ++ ++ + A E N E A Q+ E +E+ S L E
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN-ESARQQLERQNKELRSKLHEM 1804
Query: 267 LASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALAS------KDREILRLLKDVQHL 320
+V S + + + +AA S K +EIL ++D + +
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864
Query: 321 QSSLQELEEASANQIADLERQLTAKSEAIEKL---EEKLQAQSD 361
+E E ++ L+RQL E +++ KLQ + D
Sbjct: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1908
Score = 42.7 bits (99), Expect = 0.003
Identities = 47/221 (21%), Positives = 102/221 (46%), Gaps = 39/221 (17%)
Query: 183 AEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLI 242
A K++ L+E+ + ARL E E++ + L + K ++L+L + +EE A++
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR------- 966
Query: 243 MTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAA 302
+K A+ +++ L +++ + D N L +L
Sbjct: 967 ----QKLQLEKVTAEAKIKKLEDEILVM----------------DDQNNKLSKERKL--- 1003
Query: 303 LASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEA---IEKLEEKLQAQ 359
L + ++ L + + +L +L+ + I++LE +L + ++ +EKL+ KL+
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 360 -SDYEE----IKTELSILKAMKLASSTCSLPQGMAKPEDSL 395
SD+ E ++ +++ LK M+LA L +A+ +D +
Sbjct: 1064 ASDFHEQIADLQAQIAELK-MQLAKKEEELQAALARLDDEI 1103
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 57.4 bits (137), Expect = 1e-07
Identities = 70/233 (30%), Positives = 80/233 (34%), Gaps = 64/233 (27%)
Query: 377 LASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPEEDPSEDDSIKDSLGTE 436
LA P +A P L + A FP Q SL SP P +
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840
Query: 437 QSYPSPQQLP-------PP------------------PGPEDPLSPSPGQPLLGPSL--- 468
Q PSP P PP PGP P S SP L GP L
Sbjct: 841 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 900
Query: 469 ----------------GPDGTRTFSLSPFPSLAS-----GERLMMPPAAFKGEAGGLLVF 507
GP+G S P LA+ R PP AF+G G L +
Sbjct: 901 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 960
Query: 508 PPA-----------FYGAKPPTAPATPAPGP-EPLGGPEPADGGGGGAAGPGA 548
PPA Y + P + ATPAPG +P GP P GG AAG GA
Sbjct: 961 PPATGPGSADGLCTIYETEGPES-ATPAPGALDP--GPSPGTSGGKAAAGAGA 1010
Score = 42.0 bits (97), Expect = 0.004
Identities = 40/151 (26%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 1313 SQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGER 1372
S P SG +G P HP P GL + P + P P+L P S
Sbjct: 250 SSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRKDA-APALGPLSSSPLAT- 306
Query: 1373 LHPDPLSFKSAS----ESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAP 1428
P P K+ +++ L +L ++P + SP S PSPP P
Sbjct: 307 --PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
Query: 1429 PAKVPSASPTADMAGALHPSAKVNPNLQRRH 1459
P++ P + T M PS + P +Q H
Sbjct: 365 PSQAPPSMTTPPMQAP--PSLQTIPPIQVPH 393
Score = 42.0 bits (97), Expect = 0.004
Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 19/141 (13%)
Query: 1327 PPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHP--DPLSFKSAS 1384
PP + P PP + L +A P P+ ++H Q + P P S ++
Sbjct: 628 PPLQAPPSPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Query: 1385 ESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPS---------PPGAPPAKVPSA 1435
S + S PS A+ P + V P P +S P+SPS P APP +VP +
Sbjct: 684 PVSPSATPPSQAPPSLAAPP---LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 1436 SPTA-DMAGALHPSAKVNPNL 1455
P + M+ + P +V P L
Sbjct: 741 PPASPPMSPSATPPPRVPPLL 761
Score = 41.2 bits (95), Expect = 0.008
Identities = 42/129 (32%), Positives = 50/129 (38%), Gaps = 19/129 (14%)
Query: 413 PSLLASP--EEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGP 470
P LLA+P + PS S+ SP PPP P +P P Q L P
Sbjct: 758 PPLLAAPPLQVPPSPPASLP---------MSPLAKPPPQAPPALATP-PLQALPSPPASF 807
Query: 471 DGTRTFSLSPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPL 530
G FS P SL PP A A LL PP+ PP +P AP P
Sbjct: 808 PGQAPFS--PSASLPMSPLATPPPQAPPVLAAPLLQVPPS-----PPASPTLQAPRRPPT 860
Query: 531 GGPEPADGG 539
GP+ + G
Sbjct: 861 PGPDTSVSG 869
Score = 37.0 bits (84), Expect = 0.14
Identities = 58/225 (25%), Positives = 77/225 (34%), Gaps = 35/225 (15%)
Query: 1254 PDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQD-KAQVRIKQEQMEEDAEEEAG 1312
P TP S + P + LQ P +PL T +A + ++ A
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA- 638
Query: 1313 SQPQDSGELDKGQGP----------PKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLH 1362
S P Q P P P PP P P S P PS
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP--------VQAPFSPPASPPVSPSAT 690
Query: 1363 PQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSP--GLMMSVSPVPSSSAPI 1420
P S+A L PL + +S + S P A P + V P P +S P+
Sbjct: 691 PP--SQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747
Query: 1421 SPS--PP-------GAPPAKVPSASPTA-DMAGALHPSAKVNPNL 1455
SPS PP APP +VP + P + M+ P + P L
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Score = 35.8 bits (81), Expect = 0.32
Identities = 32/104 (30%), Positives = 38/104 (36%), Gaps = 10/104 (9%)
Query: 441 SPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSP----FPSLASGERLMMPPAA 496
+P PP P + P SP P P + PS P SL+ P M P A
Sbjct: 663 APFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 497 FKGEAGGLLVFPPAFYGAKPPTAP-----ATPAPGPEPLGGPEP 535
+A L PP PP +P ATP P PL P
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Score = 35.8 bits (81), Expect = 0.32
Identities = 31/116 (26%), Positives = 38/116 (32%), Gaps = 6/116 (5%)
Query: 419 PEEDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSL 478
P P + S P Q+PP P P+SPS P P P +
Sbjct: 680 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLAAPPLQV 737
Query: 479 SPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTA-PATPAPGPEPLGGP 533
P P + M P A LL PP PP + P +P P P P
Sbjct: 738 PPSPPASPP---MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790
Score = 35.4 bits (80), Expect = 0.41
Identities = 31/99 (31%), Positives = 39/99 (39%), Gaps = 18/99 (18%)
Query: 437 QSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSPFPSLASGERLMMPPAA 496
Q+ PSP PPP P +P P P P+L + P LA+ PP
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAP---PALASPPLQGLPSPPLSPLAT------PPP- 619
Query: 497 FKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEP 535
+A L PP PP+ PA+P PL P P
Sbjct: 620 ---QAPPXLALPPL---QAPPSPPASPP--LSPLATPSP 650
Score = 34.3 bits (77), Expect = 0.92
Identities = 50/217 (23%), Positives = 68/217 (31%), Gaps = 28/217 (12%)
Query: 1236 PDLDPSGGPGILPPGHSHPDPTPQSPDS------ETEDQKPTVKELELQEGPEENSTPLT 1289
P L P PP P PQ+P + P + P PL
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL 761
Query: 1290 TQDKAQVRIKQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPG-- 1347
QV S P Q PP P P PG
Sbjct: 762 AAPPLQV----------PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811
Query: 1348 PLLPGGSTPDCPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLM 1407
P P S P P P ++ P L+ +L +P +PG
Sbjct: 812 PFSPSASLPMSPLATPPPQA-------PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
Query: 1408 MSVSPVPSSSAPISPSPPGAPPAKVPSASPTA-DMAG 1443
SVS P + ++P PP PP++ PS++ + D+AG
Sbjct: 865 TSVSG-PRLTLALAPGPP-PPPSRSPSSTLSGPDLAG 899
Score = 33.5 bits (75), Expect = 1.6
Identities = 105/455 (23%), Positives = 154/455 (33%), Gaps = 55/455 (12%)
Query: 437 QSYPSPQQLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSPFPSLASGERLMMPPAA 496
Q+ PQ PP L P PL PS P GT+ + P + A+ +PP+
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPS--PSGTKARPVPPPDNAATPLPATLPPS- 334
Query: 497 FKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGGPEPADGGGGGAAGPGAEEEQLDTA 556
A L + PP+ + PP+ P+P P P+ P L T
Sbjct: 335 -PPLATPLPLAPPS--PSAPPSLQTLPSPPATP-----PSQAPPSMTTPPMQAPPSLQTI 386
Query: 557 EIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFL 616
QV L ++ L LS + L P T++ F+ M
Sbjct: 387 P-PIQVPHSLTSPSLQA---PPSPLALSSLQATTSLGSP------TLQATHSFLTM---- 432
Query: 617 SDEQNVLALRTIQVRQRGSITPRIRTP-----ETGSDDAIKSILEQAKKEIESQKGGEPK 671
S Q +L + R + TP P + +++ L A + S P
Sbjct: 433 SPRQTQASLTS---PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 672 TSVAPLSIANGTTPASTSEDAIKSILEQARREMQAQQQALLEMEVAPRGRSVPPSPPERP 731
+++ L AS S A S L E Q+ A ++ P + PP P
Sbjct: 490 QALSSL--------ASHSPQAPLSSLIMPPLETQS-SLAPPSLQTPPASLTTPPL-ENLP 539
Query: 732 SLATASQNGAPALVKQEEGSGGPAQAPLPVLSPAAFVQSIIRKVKSEIGDAGYFDHHWAS 791
SLA A A + P AP P+ +P + + + + S I +
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP-----QA 594
Query: 792 DRGLLSRPYASV-SPSLSSSSSSGYSGQPNGRAWPRGDEAPVPPEDEAAAGAEDEPPRTG 850
L S P + SP LS ++ P A P P PP A P T
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPP-XLALPPLQAPPSPP-----ASPPLSPLATP 648
Query: 851 ELKAEGATAEAGARLPYYPAYVPRTLKPTVPPLTP 885
+A A A + P+ P P P PP +P
Sbjct: 649 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Score = 33.5 bits (75), Expect = 1.6
Identities = 48/205 (23%), Positives = 66/205 (32%), Gaps = 25/205 (12%)
Query: 1236 PDLDPSGGPGILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQ 1295
P P P PP S P+ +P + P + P + P Q
Sbjct: 679 PPASPPVSPSATPP--SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736
Query: 1296 VRIKQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGST 1355
V A P+ L PP + P PP + + +A P
Sbjct: 737 VP-PSPPASPPMSPSATPPPRVPPLL---AAPPLQVPPSPPASLPMSPLAKPP------- 785
Query: 1356 PDCPSLHPQQESEAGERLHPDPLSFKS-ASESSRCSLEVS-LNSPSAASSPGLMMSVSPV 1413
P P + + L P SF A S SL +S L +P + P L + V
Sbjct: 786 ---PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842
Query: 1414 PSSSAPISPSPPGAPPAKVPSASPT 1438
P PSPP +P + P PT
Sbjct: 843 P-------PSPPASPTLQAPRRPPT 860
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 56.6 bits (135), Expect = 2e-07
Identities = 65/265 (24%), Positives = 102/265 (38%), Gaps = 25/265 (9%)
Query: 288 KVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSE 347
K++ L + L+ + + + + L+D+Q + +L ++ A + DLE +++ +
Sbjct: 478 KLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTG 537
Query: 348 AIEKLEEKLQAQSDYEEIKTELSILKAMKLA-----SSTCSLPQGMAKPEDSLLIAKEAF 402
+ KL ++L E+ K E++ L A + S +P P DS I
Sbjct: 538 EVAKLTKEL------EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPP 591
Query: 403 FPTQKFLLEKPSLLASPEEDPSEDDSIKDSLGTEQSYPSPQQL-PPPPGPEDPLSPSP-- 459
P P P P + + + S P + PPPP D P P
Sbjct: 592 APGDSTTPPPPP--PPPPPPPPLPGGV--CISSPPSLPGGTAISPPPPLSGDATIPPPPP 647
Query: 460 ---GQPLLGPSLGPDGTRTFSLSPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKP 516
G + PS P GT ++ P P L R+ PP G AG + PP G
Sbjct: 648 LPEGVGIPSPSSLPGGT---AIPPPPPLPGSARIPPPPPPLPGSAG-IPPPPPPLPGEAG 703
Query: 517 PTAPATPAPGPEPLGGPEPADGGGG 541
P P PG + P P GG G
Sbjct: 704 MPPPPPPLPGGPGIPPPPPFPGGPG 728
Score = 39.7 bits (91), Expect = 0.022
Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 10/181 (5%)
Query: 1259 QSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGSQPQDS 1318
+ D E E + T + +L + E+ + + A + + A P DS
Sbjct: 524 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDS 583
Query: 1319 GELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHPDPL 1378
G + P + PP P P P LPGG P P G + P P
Sbjct: 584 GTIIPPPPAPGDSTTPPPPP---PPPPPPPPLPGGVCISSPPSLP-----GGTAISPPPP 635
Query: 1379 SFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPVP-SSSAPISPSPPGAP-PAKVPSAS 1436
A+ L + PS +S PG P P SA I P PP P A +P
Sbjct: 636 LSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP 695
Query: 1437 P 1437
P
Sbjct: 696 P 696
Score = 33.5 bits (75), Expect = 1.6
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Query: 482 PSLASGERLMMPPAA-FKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGG----PEPA 536
PS+ S R +PPA G++G ++ PPA + P P P P P PL G P
Sbjct: 565 PSVPS--RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 622
Query: 537 DGGGGGAAGP 546
GG A P
Sbjct: 623 SLPGGTAISP 632
Score = 32.0 bits (71), Expect = 4.6
Identities = 43/199 (21%), Positives = 64/199 (32%), Gaps = 30/199 (15%)
Query: 1262 DSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQM---EEDAEEEAGSQPQDS 1318
DSE + E++ E E +K + +++Q+ ++D E E +
Sbjct: 480 DSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEV 539
Query: 1319 GELDKGQGPPKEEHPD--------PPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAG 1370
+L K K+E PP V P P LPG S P +S
Sbjct: 540 AKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTP 599
Query: 1371 ERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPA 1430
P P P G+ +S P ISP PP + A
Sbjct: 600 PPPPPPP-------------------PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 640
Query: 1431 KVPSASPTADMAGALHPSA 1449
+P P + G PS+
Sbjct: 641 TIPPPPPLPEGVGIPSPSS 659
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 56.6 bits (135), Expect = 2e-07
Identities = 65/265 (24%), Positives = 102/265 (38%), Gaps = 25/265 (9%)
Query: 288 KVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSE 347
K++ L + L+ + + + + L+D+Q + +L ++ A + DLE +++ +
Sbjct: 487 KLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTG 546
Query: 348 AIEKLEEKLQAQSDYEEIKTELSILKAMKLA-----SSTCSLPQGMAKPEDSLLIAKEAF 402
+ KL ++L E+ K E++ L A + S +P P DS I
Sbjct: 547 EVAKLTKEL------EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPP 600
Query: 403 FPTQKFLLEKPSLLASPEEDPSEDDSIKDSLGTEQSYPSPQQL-PPPPGPEDPLSPSP-- 459
P P P P + + + S P + PPPP D P P
Sbjct: 601 APGDSTTPPPPP--PPPPPPPPLPGGV--CISSPPSLPGGTAISPPPPLSGDATIPPPPP 656
Query: 460 ---GQPLLGPSLGPDGTRTFSLSPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKP 516
G + PS P GT ++ P P L R+ PP G AG + PP G
Sbjct: 657 LPEGVGIPSPSSLPGGT---AIPPPPPLPGSARIPPPPPPLPGSAG-IPPPPPPLPGEAG 712
Query: 517 PTAPATPAPGPEPLGGPEPADGGGG 541
P P PG + P P GG G
Sbjct: 713 MPPPPPPLPGGPGIPPPPPFPGGPG 737
Score = 39.7 bits (91), Expect = 0.022
Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 10/181 (5%)
Query: 1259 QSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGSQPQDS 1318
+ D E E + T + +L + E+ + + A + + A P DS
Sbjct: 533 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDS 592
Query: 1319 GELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHPDPL 1378
G + P + PP P P P LPGG P P G + P P
Sbjct: 593 GTIIPPPPAPGDSTTPPPPP---PPPPPPPPLPGGVCISSPPSLP-----GGTAISPPPP 644
Query: 1379 SFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPVP-SSSAPISPSPPGAP-PAKVPSAS 1436
A+ L + PS +S PG P P SA I P PP P A +P
Sbjct: 645 LSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP 704
Query: 1437 P 1437
P
Sbjct: 705 P 705
Score = 33.5 bits (75), Expect = 1.6
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Query: 482 PSLASGERLMMPPAA-FKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEPLGG----PEPA 536
PS+ S R +PPA G++G ++ PPA + P P P P P PL G P
Sbjct: 574 PSVPS--RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631
Query: 537 DGGGGGAAGP 546
GG A P
Sbjct: 632 SLPGGTAISP 641
Score = 32.0 bits (71), Expect = 4.6
Identities = 43/199 (21%), Positives = 64/199 (32%), Gaps = 30/199 (15%)
Query: 1262 DSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQM---EEDAEEEAGSQPQDS 1318
DSE + E++ E E +K + +++Q+ ++D E E +
Sbjct: 489 DSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEV 548
Query: 1319 GELDKGQGPPKEEHPD--------PPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAG 1370
+L K K+E PP V P P LPG S P +S
Sbjct: 549 AKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTP 608
Query: 1371 ERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPA 1430
P P P G+ +S P ISP PP + A
Sbjct: 609 PPPPPPP-------------------PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 649
Query: 1431 KVPSASPTADMAGALHPSA 1449
+P P + G PS+
Sbjct: 650 TIPPPPPLPEGVGIPSPSS 668
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 55.8 bits (133), Expect = 3e-07
Identities = 71/370 (19%), Positives = 157/370 (42%), Gaps = 39/370 (10%)
Query: 16 DLRRLQKELNSVASELSARQEESEH-------SHKHLIELRREFKKNVPEEIR--EMVAP 66
DL + L + ELS R EE E S + L + E K+ + EE + +A
Sbjct: 1276 DLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH 1335
Query: 67 VLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQ 126
L+S + + L ++ +E + A + + L +A V + D + Q
Sbjct: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETD----------AIQ 1385
Query: 127 PRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEA--- 183
+L + K+ + L E+ T+ + E ++ + G+ L+R+
Sbjct: 1386 RTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTK-QRLQGEVEDLMRDLERSHTACA 1444
Query: 184 ---EKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVG 240
+KQ+ +V +L E++ +++ ++ EL ++R Y+E
Sbjct: 1445 TLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEE---------- 1494
Query: 241 LIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLE 300
++ LE + + Q E+ L EQ+A +++ A + + +K + + +E
Sbjct: 1495 -VVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVAL-EEVE 1552
Query: 301 AALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEK-LEEKLQAQ 359
+L ++ +ILR+ ++ ++S L +I L+R +EA++ L+ +++++
Sbjct: 1553 GSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSR 1612
Query: 360 SDYEEIKTEL 369
+D +K ++
Sbjct: 1613 NDALRLKKKM 1622
Score = 37.0 bits (84), Expect = 0.14
Identities = 40/194 (20%), Positives = 81/194 (41%), Gaps = 30/194 (15%)
Query: 184 EKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIM 243
+++K LQE L E+K+ L + + +L ++E +AD
Sbjct: 998 KEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRAD------ 1051
Query: 244 TNLEKANQRAEA----AQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRL 299
LE+A ++ E +Q + L + ++ K F L +L
Sbjct: 1052 --LERAKRKLEGDLKMSQESIMDLENDKQQIEEKLK------------KKEFELS---QL 1094
Query: 300 EAALASKDREILRLLKDVQHLQSSLQELEE---ASANQIADLERQLTAKSEAIEKLEEKL 356
+A + + L+ K ++ LQ+ ++ELEE A A +E+Q + + +E++ E+L
Sbjct: 1095 QAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERL 1154
Query: 357 QAQSDYEEIKTELS 370
+ S + E++
Sbjct: 1155 EEASGATSAQIEMN 1168
Score = 37.0 bits (84), Expect = 0.14
Identities = 37/184 (20%), Positives = 79/184 (42%), Gaps = 8/184 (4%)
Query: 179 QRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADE 238
Q + + QK ++E+Q AR+ E EE+I+ H+ + + +L R+ +E + +
Sbjct: 1102 QVHSLQFQKKIKELQ----ARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157
Query: 239 VGLIMTNLEKANQRA---EAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCS 295
G +E +R + +R++E Q + +++R G++++
Sbjct: 1158 SGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRV 1217
Query: 296 GPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEK 355
+LE + EI + +++ L S +E + + D ++ AK E +L
Sbjct: 1218 KQKLEKEKSELKMEIDDMASNIEALSKSKSNIER-TCRTVEDQFSEIKAKDEQQTQLIHD 1276
Query: 356 LQAQ 359
L Q
Sbjct: 1277 LNMQ 1280
Score = 35.4 bits (80), Expect = 0.41
Identities = 71/376 (18%), Positives = 144/376 (38%), Gaps = 49/376 (13%)
Query: 19 RLQKELNSVASELSARQEE--SEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQAEVV 76
+ QK++ + + + +EE +EH+ + IE +R EEI E + + A++
Sbjct: 1107 QFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIE 1166
Query: 77 ALSKRSQEAEAAFLSVYKQLIEAP-------------DPVPVFEAARSLDD--RLQPPSF 121
KR EA F + + L EA V E +D+ R++
Sbjct: 1167 MNKKR----EAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLE 1222
Query: 122 DPSGQPRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRN 181
+ + ++ L K E T + L+ + +Q+
Sbjct: 1223 KEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKA 1282
Query: 182 EAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGL 241
+ Q G L+ R+ E E I L + +A +L EL+R+ +EE +K
Sbjct: 1283 RLQTQNG------ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHA 1336
Query: 242 IMTNLEKANQRAEAAQREVES---LREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPR 298
+ ++ + E + E E+ L+ L+ NS + + + + + R
Sbjct: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV----------AQWRTKYETDAIQR 1386
Query: 299 LEAALASKDREILRLLKDVQHLQ------SSLQELEEASANQIADLERQLTAKSEAIEKL 352
E +K + RL + ++ + +SL++ ++ ++ DL R L A L
Sbjct: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446
Query: 353 EEKLQAQSDYEEIKTE 368
++K Q +++++ E
Sbjct: 1447 DKK---QRNFDKVLAE 1459
Score = 32.3 bits (72), Expect = 3.5
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 6/100 (6%)
Query: 179 QRNEAEKQKGLQEVQITLAARLGEAEE---KIKVLHSALKATQAELLELRRKYDE---EA 232
Q+ AE KG + + + +AEE I L + QA++ +R+ +E +A
Sbjct: 1834 QKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQA 1893
Query: 233 ASKADEVGLIMTNLEKANQRAEAAQREVESLREQLASVNS 272
++ + LE+A +RA+ A+ +V LR + V S
Sbjct: 1894 NTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGS 1933
>gi|139394646 iroquois homeobox protein 5 [Homo sapiens]
Length = 483
Score = 55.1 bits (131), Expect = 5e-07
Identities = 63/265 (23%), Positives = 91/265 (34%), Gaps = 23/265 (8%)
Query: 1187 YQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPGI 1246
++ PYP++ +L+ + V WF N R R+++E + T D I
Sbjct: 135 HRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENI 194
Query: 1247 LPPGHSHPDPTPQSPDSETEDQKPTV--KELELQEGPEENSTPLTTQDKAQVRIKQEQME 1304
+ + PQ P+ + + + P E + G E P T K + E
Sbjct: 195 --DLEKNDEDEPQKPEDKGDPEGPEAGGAEQKAASGCERLQGPPTPAGK--------ETE 244
Query: 1305 EDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPG-------NDGLPKVAPGPLLPGGSTPD 1357
+ +P G LD QGPP+ P P G D P G P G P
Sbjct: 245 GSLSDSDFKEPPSEGRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAP-GPHPA 303
Query: 1358 CPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPVPSSS 1417
+ P + P P ++ SL S G SP P
Sbjct: 304 AGEVPPGPGGPSVIHSPPPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGNEGSPCPPCP 363
Query: 1418 APISPSPPG---APPAKVPSASPTA 1439
PI+ G A PA PS SP+A
Sbjct: 364 GPIAGQALGGSRASPAPAPSRSPSA 388
Score = 36.6 bits (83), Expect = 0.19
Identities = 41/134 (30%), Positives = 51/134 (38%), Gaps = 20/134 (14%)
Query: 421 EDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPE----DPLSPSPGQPLLGPSL--GPDGTR 474
ED E+++I E P+ P GPE + + S + L GP G +
Sbjct: 186 EDEEEEENIDLEKNDEDEPQKPEDKGDPEGPEAGGAEQKAASGCERLQGPPTPAGKETEG 245
Query: 475 TFSLSPF---PSLASGERLMMPPAAF----KGEAGGLLVFPPAFYGAKPPTAPA-TPAPG 526
+ S S F PS + L PP G A L PA P PA PAPG
Sbjct: 246 SLSDSDFKEPPSEGRLDALQGPPRTGGPSPAGPAAARLAEDPA------PHYPAGAPAPG 299
Query: 527 PEPLGGPEPADGGG 540
P P G P GG
Sbjct: 300 PHPAAGEVPPGPGG 313
Score = 35.0 bits (79), Expect = 0.54
Identities = 39/138 (28%), Positives = 54/138 (39%), Gaps = 45/138 (32%)
Query: 413 PSLLASPE-----EDPSEDDSIKDSLGTEQSYPSPQQLPPPPGPEDPLSPSPGQPLLGPS 467
P++LA P+ E + D +KD G + P P P PG P+ G +
Sbjct: 326 PAVLAKPKLWSLAEIATSSDKVKDGGGGNEGSPCP--------------PCPG-PIAGQA 370
Query: 468 LGPDGTRTFSLSPFPSLASGERLMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPAT----- 522
LG G+R S +P PS + + P GG ++ P +Y A P P
Sbjct: 371 LG--GSRA-SPAPAPSRSPSAQCPFP--------GGTVLSRPLYYTA--PFYPGYTNYGS 417
Query: 523 -------PAPGPEPLGGP 533
P PGP P GP
Sbjct: 418 FGHLHGHPGPGPGPTTGP 435
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 54.3 bits (129), Expect = 9e-07
Identities = 86/412 (20%), Positives = 168/412 (40%), Gaps = 22/412 (5%)
Query: 20 LQKELNSVASELSARQEESEHSHKHLIELRREFK--KNVPEEIREMVAPVLKS---FQAE 74
LQ E+ V ELS + E L L +F K E ++E + + Q E
Sbjct: 464 LQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTE 523
Query: 75 VVALSKRSQEAEAAFLSVYKQLIE-APDPVPVFEAARSLDDRLQPPSFDPSGQPRR--DL 131
V AL R +E E KQ+ + A + L D L + ++ +L
Sbjct: 524 VDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENL 583
Query: 132 HTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLP---GIPGKALLTETLLQRNEAEKQKG 188
+ + +S ++R + A T T+ + + K E L ++ + ++++
Sbjct: 584 QEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREK 643
Query: 189 LQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEK 248
+E+ L + +EK+ +L L +A LL+L+ E A+S A + L+
Sbjct: 644 QEEID-NYKKDLKDLKEKVSLLQGDLSEKEASLLDLK----EHASSLASSGLKKDSRLKT 698
Query: 249 ANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDR 308
E + E + QL + + A SP+ D++ R + +
Sbjct: 699 LEIALEQKKEECLKMESQLKKAHEAALEARASPE--MSDRIQHLEREITRYKDESSKAQA 756
Query: 309 EILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEIKTE 368
E+ RLL+ ++ +++ + ++ +IA+LERQ+ +++ + L+ K Q + E
Sbjct: 757 EVDRLLEILKEVENEKNDKDK----KIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLE 812
Query: 369 LSILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPE 420
+ + L S+ L + K +D + +EA + + E+ +LA E
Sbjct: 813 EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE 864
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 53.5 bits (127), Expect = 1e-06
Identities = 83/411 (20%), Positives = 169/411 (41%), Gaps = 26/411 (6%)
Query: 16 DLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVAPVLKSFQAEV 75
+L R EL ++ ++L + S +H+ L+ +E A +L Q EV
Sbjct: 446 ELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTA------KEQRAAIL---QTEV 496
Query: 76 VALSKRSQEAEAAFLSVYKQLIE-APDPVPVFEAARSLDDRLQPPSFDPSGQPRR--DLH 132
AL R +E E KQ+ + A + L D L + ++ +L
Sbjct: 497 DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQ 556
Query: 133 TSWKRNPELLSPKEQREGTSPAGPTLTEGSRLP---GIPGKALLTETLLQRNEAEKQKGL 189
+ + +S ++R + A T T+ + + K E L ++ + ++++
Sbjct: 557 EQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQ 616
Query: 190 QEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKA 249
+E+ L + +EK+ +L L +A LL+L+ E A+S A + L+
Sbjct: 617 EEID-NYKKDLKDLKEKVSLLQGDLSEKEASLLDLK----EHASSLASSGLKKDSRLKTL 671
Query: 250 NQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDRE 309
E + E + QL + + A SP+ D++ R + + E
Sbjct: 672 EIALEQKKEECLKMESQLKKAHEAALEARASPE--MSDRIQHLEREITRYKDESSKAQAE 729
Query: 310 ILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEIKTEL 369
+ RLL+ ++ +++ + ++ +IA+LERQ+ +++ + L+ K Q + E
Sbjct: 730 VDRLLEILKEVENEKNDKDK----KIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEE 785
Query: 370 SILKAMKLASSTCSLPQGMAKPEDSLLIAKEAFFPTQKFLLEKPSLLASPE 420
+ + L S+ L + K +D + +EA + + E+ +LA E
Sbjct: 786 ARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE 836
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,457,998
Number of Sequences: 37866
Number of extensions: 4470684
Number of successful extensions: 56919
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 363
Number of HSP's successfully gapped in prelim test: 2042
Number of HSP's that attempted gapping in prelim test: 32174
Number of HSP's gapped (non-prelim): 22836
length of query: 1486
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1371
effective length of database: 13,892,928
effective search space: 19047204288
effective search space used: 19047204288
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.