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Search of human proteins with 239743051
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo
sapiens]
(306 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo ... 619 e-177
gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 434 e-122
gi|239508698 PREDICTED: similar to mucin [Homo sapiens] 409 e-114
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 64 1e-10
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 61 1e-09
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 61 1e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 60 3e-09
gi|60097902 filaggrin [Homo sapiens] 58 9e-09
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 57 3e-08
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 57 3e-08
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 57 3e-08
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 57 3e-08
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 56 3e-08
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 55 8e-08
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 53 3e-07
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 53 3e-07
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 52 5e-07
gi|91208420 bassoon protein [Homo sapiens] 52 5e-07
gi|57864582 hornerin [Homo sapiens] 52 7e-07
gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ... 52 9e-07
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 52 9e-07
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 51 1e-06
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 51 1e-06
gi|239756562 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-06
gi|42821110 hypothetical protein LOC340602 [Homo sapiens] 50 2e-06
gi|24497589 aristaless related homeobox [Homo sapiens] 50 2e-06
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s... 50 3e-06
gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo ... 50 3e-06
gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo ... 50 3e-06
gi|239750916 PREDICTED: similar to hCG1803335 [Homo sapiens] 49 4e-06
>gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo
sapiens]
Length = 306
Score = 619 bits (1595), Expect = e-177
Identities = 306/306 (100%), Positives = 306/306 (100%)
Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD
Sbjct: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR
Sbjct: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAA 180
EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAA
Sbjct: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAA 180
Query: 181 PVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQR 240
PVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQR
Sbjct: 181 PVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQR 240
Query: 241 AQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSE 300
AQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSE
Sbjct: 241 AQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSE 300
Query: 301 EMEEEG 306
EMEEEG
Sbjct: 301 EMEEEG 306
>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
Length = 417
Score = 434 bits (1115), Expect = e-122
Identities = 254/411 (61%), Positives = 266/411 (64%), Gaps = 112/411 (27%)
Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD
Sbjct: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
Query: 61 QQGAQDREEEAAAAPA------------------PTSRGHRTEKRKPQQPQRRPAGGTGQ 102
QQGAQDREEEAAAAPA PTS GHRTEKRK Q Q +PAGGTGQ
Sbjct: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 120
Query: 103 RRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCS 162
RRGSRSS SADQQ AQDREEEAAAAP PTS GHRTEKRK QQPQ RPA GTGQRRGSG S
Sbjct: 121 RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSS 180
Query: 163 PSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPS----- 217
PSADQQ AQDREEEA AAP PTS GHRTEKRK Q QC+PAGGTGQRRGSRSSPS
Sbjct: 181 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQR 240
Query: 218 ------------------------------RQPAGGTGQRRGSRSSPSADQQRAQDREEE 247
R+PAGGTGQRRGS SPSADQQ AQDREEE
Sbjct: 241 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEE 300
Query: 248 AA------------------QPQRRPAGGTGQRRGT------------------AAAPVP 271
AA Q Q +PAGGTGQRRG+ AAAPVP
Sbjct: 301 AAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVP 360
Query: 272 TTGG------------------TGQRRGTAAAPAPTSTGTGQRRGSEEMEE 304
T+ G TGQRRG+ ++P+ Q+R + EE
Sbjct: 361 TSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPS-----ADQQRAQDREEE 406
Score = 368 bits (944), Expect = e-102
Identities = 195/256 (76%), Positives = 201/256 (78%), Gaps = 35/256 (13%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
R +QQPQ +PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ
Sbjct: 158 RKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 217
Query: 94 RRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGT 153
RPAGGTGQRRGSRSS SADQQ AQDREEEAAAAPAPTS GHRTEKRKPQQPQ RPA GT
Sbjct: 218 CRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGT 277
Query: 154 GQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSR 213
GQRRGSG SPSADQQ AQDREEEA AAP PTSSGHRTEKRKRLQLQCQPAGGTGQRRGS
Sbjct: 278 GQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSG 337
Query: 214 SS-----------------------------------PSRQPAGGTGQRRGSRSSPSADQ 238
S P R+PA GTGQRRGS SSPSADQ
Sbjct: 338 CSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQ 397
Query: 239 QRAQDREEEAAQPQRR 254
QRAQDREEE + ++R
Sbjct: 398 QRAQDREEEVRKWKKR 413
>gi|239508698 PREDICTED: similar to mucin [Homo sapiens]
Length = 265
Score = 409 bits (1051), Expect = e-114
Identities = 222/293 (75%), Positives = 224/293 (76%), Gaps = 53/293 (18%)
Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD
Sbjct: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
Query: 61 QQGAQDREEEAAAAPA------------------PTSRGHRTEKRKPQQPQRRPAGGTGQ 102
QQGAQDREEEAAAAPA PTS GHRTEKRKPQQPQ RPAGGTGQ
Sbjct: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120
Query: 103 RRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCS 162
RRGS SS SADQQGAQDREEEAAAAPAPTS GHRTEKRKPQQPQ RPAAGTGQRRGS S
Sbjct: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180
Query: 163 PSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAG 222
PSADQQ AQDREEEA AAPVPTS GHRTEKRKR Q QC+PA GTGQRR
Sbjct: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRR------------ 228
Query: 223 GTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGG 275
GSRSSPSADQQRAQDREEEA AAAP PT+ G
Sbjct: 229 ------GSRSSPSADQQRAQDREEEA-----------------AAAPAPTSSG 258
Score = 302 bits (774), Expect = 2e-82
Identities = 155/191 (81%), Positives = 159/191 (83%), Gaps = 4/191 (2%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
+Q+ QD + EK KP QQPQC+PAGGTGQRRGSGSSPSADQQG
Sbjct: 79 QQRAQDREEEAAAAPAPTSSGHRTEKRKP----QQPQCRPAGGTGQRRGSGSSPSADQQG 134
Query: 64 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEE 123
AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA GTGQRRGSRSS SADQQGAQDREEE
Sbjct: 135 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEE 194
Query: 124 AAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVP 183
AAAAP PTS GHRTEKRK QQPQCRPAAGTGQRRGS SPSADQQRAQDREEEA AAP P
Sbjct: 195 AAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254
Query: 184 TSSGHRTEKRK 194
TSSGHRTEKRK
Sbjct: 255 TSSGHRTEKRK 265
Score = 188 bits (477), Expect = 6e-48
Identities = 100/139 (71%), Positives = 109/139 (78%), Gaps = 1/139 (0%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
P +Q + R+ ++ +T+ +P QQPQ +PA GTGQRRGS SSPSADQQ
Sbjct: 128 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKP-QQPQRRPAAGTGQRRGSRSSPSADQQ 186
Query: 63 GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREE 122
GAQDREEEAAAAP PTSRGHRTEKRK QQPQ RPA GTGQRRGSRSS SADQQ AQDREE
Sbjct: 187 GAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREE 246
Query: 123 EAAAAPAPTSSGHRTEKRK 141
EAAAAPAPTSSGHRTEKRK
Sbjct: 247 EAAAAPAPTSSGHRTEKRK 265
Score = 103 bits (256), Expect = 2e-22
Identities = 78/197 (39%), Positives = 87/197 (44%), Gaps = 90/197 (45%)
Query: 193 RKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAA--- 249
R + Q QCQPAGGTGQRRGS SSPS G + + ++P+ADQQRAQDREEEAA
Sbjct: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAP 93
Query: 250 ---------------QPQRRPAGGTGQRRGT------------------AAAPVPTT--- 273
QPQ RPAGGTGQRRG+ AAAP PT+
Sbjct: 94 APTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH 153
Query: 274 ---------------GGTGQRRGT------------------AAAPAPTS---------- 290
GTGQRRG+ AAAP PTS
Sbjct: 154 RTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKR 213
Query: 291 --------TGTGQRRGS 299
GTGQRRGS
Sbjct: 214 QQPQCRPAAGTGQRRGS 230
Score = 45.1 bits (105), Expect = 8e-05
Identities = 37/112 (33%), Positives = 45/112 (40%), Gaps = 40/112 (35%)
Query: 228 RGSRSSPSADQQRAQDREEEAA---QPQRRPAGGTGQRRGTAAAPVPTTGGTGQR----- 279
R R S DQ ++ + QPQ +PAGGTGQRRG+ ++P G R
Sbjct: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72
Query: 280 --------------RGTAAAPAPTST------------------GTGQRRGS 299
AAAPAPTS+ GTGQRRGS
Sbjct: 73 AAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGS 124
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 64.3 bits (155), Expect = 1e-10
Identities = 71/315 (22%), Positives = 118/315 (37%), Gaps = 47/315 (14%)
Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDR---EE 69
+KLR + ++ ++P + GG G + G +P + G + R ++
Sbjct: 272 KKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQK 331
Query: 70 EAAAAPAPTSRG--------------HRTEKRKPQQPQRRPAGGTGQ-----------RR 104
AA A T RG + ++R+ ++P+R+ A G R
Sbjct: 332 ATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLRE 391
Query: 105 GSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS 164
R + Q+ A APA G ++K + + P+ + G R G G P
Sbjct: 392 AKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPR 451
Query: 165 ADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGT 224
Q+A+ + EA A S G + + R++ A GT R G S S G
Sbjct: 452 RRGQKARQKAAEAGA----ESRGDKKQGRQKAS-----AAGTKSRGGGLKSHS----GKN 498
Query: 225 GQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAA 284
RRG ++ + ++ A + + RR Q+ A A G ++R A
Sbjct: 499 LWRRGQKAEAAGEKATAAGAKSRGRKQPRR------QKPAVAGAKSRVGGSKSRQRQKAV 552
Query: 285 APAPTSTGTGQRRGS 299
A TS G G + S
Sbjct: 553 AAGATSHGGGGNKQS 567
Score = 58.9 bits (141), Expect = 5e-09
Identities = 77/309 (24%), Positives = 120/309 (38%), Gaps = 63/309 (20%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
R ++QP+ Q G + G G++ R+ + A A TS G K Q
Sbjct: 521 RGRKQPRRQKPAVAGAKSRVG--------GSKSRQRQKAVAAGATSHGGGGNK------Q 566
Query: 94 RRPAGGTGQRRGSRSSSSADQQGAQDRE---EEAAAAPAPTSSGHRTEKRKPQQPQCRPA 150
R GG R+ +++++A +G D++ ++AAA + SG +K Q+ A
Sbjct: 567 SRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQK-----A 621
Query: 151 AGTGQR--------------------------RGSGCSPSADQQRAQDREEEATAAPVPT 184
AGTG + RGSG Q+ A E + AA V
Sbjct: 622 AGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQ 681
Query: 185 SSGHRTEKRKRLQLQCQPAGGTG--------QRRGSRSSPSRQPAGGTGQRRGSRSSPSA 236
+ R + R+R + + + GG QRRG + + GG + RGS + S
Sbjct: 682 EAEARKKPRRR-RAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSR 740
Query: 237 DQQRAQDRE-EEAAQPQRRPAGGTGQRRGTAA----APVPTTGGTGQRRGTAAAPAPTST 291
A+ R ++AA + GG +RRG A T G GQ+ A P
Sbjct: 741 GSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAG-GQKAAAAGGKKPPRV 799
Query: 292 GTGQRRGSE 300
+ RG +
Sbjct: 800 KSRGGRGQK 808
Score = 55.1 bits (131), Expect = 8e-08
Identities = 74/303 (24%), Positives = 113/303 (37%), Gaps = 41/303 (13%)
Query: 21 GDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE--EEAAAAPAPT 78
GD+ L +K + + + Q G+ +A GA++R E+ AAA
Sbjct: 55 GDKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTK 114
Query: 79 SRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTE 138
S G R K + + + G R ++ S++A + ++AAAA S G
Sbjct: 115 SLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGG--- 171
Query: 139 KRKPQQPQCRPAAGTGQRRGS-----GCSPSADQQRAQDREEEATAAPVPTSSGHRTEKR 193
++PQ AAG R G G D+ + + R+ EA + T G R + R
Sbjct: 172 ----EKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDK-KGRQREAKSRFGKTRGGRRKKHR 226
Query: 194 KRLQLQCQPAGGTGQRRGSRSSPSRQPAGGT-----GQRRGSRSSPSADQQRAQDREEEA 248
+ AGG RRG P +Q G G+ R +S D++ + + A
Sbjct: 227 RPKPA----AGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAA 282
Query: 249 A-------------QPQRRPAGGTGQRRGTAAAPVPTTGGTGQRR----GTAAAPAPTST 291
+P + GG G + P GG RR T AA A T
Sbjct: 283 LAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKR 342
Query: 292 GTG 294
G G
Sbjct: 343 GGG 345
Score = 51.2 bits (121), Expect = 1e-06
Identities = 69/272 (25%), Positives = 100/272 (36%), Gaps = 61/272 (22%)
Query: 31 KPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 90
KP R + P+ + G R G G P Q A+ + EA A SRG + + R
Sbjct: 426 KPRR--RGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAE----SRGDKKQGR--- 476
Query: 91 QPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 150
Q+ A GT R G S S + ++ EAA A T++G ++ RK + Q
Sbjct: 477 --QKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKA-TAAGAKSRGRKQPRRQKPAV 533
Query: 151 AGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRR 210
AG R G ++ R+ + A TS G GG Q R
Sbjct: 534 AGAKSRVGG----------SKSRQRQKAVAAGATSHG---------------GGGNKQSR 568
Query: 211 GSRSSPSRQ----------PAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGT- 259
G + RQ GG Q +++ + R+ D ++A R+ A GT
Sbjct: 569 GGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKA---WRQKAAGTG 625
Query: 260 ----------GQRRGTAAAPVPTTGGTGQRRG 281
GQ+ AA TG T + G
Sbjct: 626 AKSRKKPWRRGQKDAAAAEKAWATGATSRGSG 657
Score = 37.4 bits (85), Expect = 0.017
Identities = 54/228 (23%), Positives = 87/228 (38%), Gaps = 32/228 (14%)
Query: 80 RGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEK 139
RGHR Q Q G G G+ + + + A+ +AA A +K
Sbjct: 4 RGHR------QCNQAAGRAGPGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDK 57
Query: 140 RKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQ 199
+ +Q + AAG + R G + + A+ ++A A + G +K
Sbjct: 58 KLRRQ---KAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAA----- 109
Query: 200 CQPAGGTGQRRGSRSSPSR--QPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAG 257
A GT G P R Q A TG ++ R + ++ AA + R
Sbjct: 110 ---AAGTKSLGGRGRKPRRRGQKAAATGSKK----------PRWRAQKSAAAGSKNR--- 153
Query: 258 GTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEE 305
G G ++ AAA V + GG ++ AA S +RRG++ +E
Sbjct: 154 GAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDE 201
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 60.8 bits (146), Expect = 1e-09
Identities = 75/271 (27%), Positives = 114/271 (42%), Gaps = 28/271 (10%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQ----DREEEAAAAPAPTSRGHRTEKRKPQ 90
P QP QP S A+ G D E A A PA SR + R+
Sbjct: 427 PTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKI 486
Query: 91 QPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQ--CR 148
QRR +R RS S A AAAA PT R E+++ + +
Sbjct: 487 LTQRR------ERYRQRSPSPAPAPAP------AAAAGPPTRKKSRRERKRSGEAKEAAS 534
Query: 149 PAAGTGQRRGSGCSP-SADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
++GT + SP + + R++DR+ + A+ +S+ R+ R R + + + T
Sbjct: 535 SSSGTQPAPPAPASPWDSKKHRSRDRKPGSHAS---SSARRRSRSRSRSRSTRRRSRSTD 591
Query: 208 QRRG-SRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTA 266
+RRG SR S SR+ +RR S S P A + R E + + R GG+ +++ +
Sbjct: 592 RRRGGSRRSRSREKRR---RRRRSASPPPATSSSSSSRRERH-RGKHRDGGGSKKKKKRS 647
Query: 267 AAPVPTTGGTGQRRGTAAAPAPT-STGTGQR 296
+ G G + A AP P+ ST G R
Sbjct: 648 RSRGEKRSGDGSEKAPAPAPPPSGSTSCGDR 678
Score = 58.9 bits (141), Expect = 5e-09
Identities = 58/282 (20%), Positives = 110/282 (39%), Gaps = 13/282 (4%)
Query: 9 DTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE 68
D++ + R+ G + + + + + + RR GS S ++ + R
Sbjct: 551 DSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSRE--KRRR 608
Query: 69 EEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAP 128
+A+P P + + +R+ + + R GG+ +++ RS S +++ E+ A AP
Sbjct: 609 RRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKK-KRSRSRGEKRSGDGSEKAPAPAP 667
Query: 129 AP---TSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTS 185
P TS G R +R+ P P+ D+ + +P P S
Sbjct: 668 PPSGSTSCGDRDSRRRGAVP---PSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPAS 724
Query: 186 SGHRTEKRKRLQLQCQPAGGTGQ---RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQ 242
S R L + GG RR S ++ S + G RR + D+ R +
Sbjct: 725 SPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDR 784
Query: 243 DREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAA 284
DR+ + + + RP + G P P + G+G +++
Sbjct: 785 DRDRDRSSKKARPPKESAPSSGPPPKP-PVSSGSGSSSSSSS 825
Score = 53.1 bits (126), Expect = 3e-07
Identities = 59/209 (28%), Positives = 86/209 (41%), Gaps = 37/209 (17%)
Query: 71 AAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAP 130
AAAA PT + R E+++ +G+ + + SSSS Q A PAP
Sbjct: 508 AAAAGPPTRKKSRRERKR-----------SGEAKEAASSSSGTQ----------PAPPAP 546
Query: 131 T----SSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSS 186
S HR+ RKP A+ + +RR S S + R+ R +T S
Sbjct: 547 ASPWDSKKHRSRDRKPGS----HASSSARRR----SRSRSRSRSTRRRSRSTDRRRGGSR 598
Query: 187 GHRT-EKRKRLQLQCQPAGGTGQRRGSRSSPSR-QPAGGTGQRRGSRSSPSADQQRAQDR 244
R+ EKR+R + P T SR R + G G ++ + S S ++R+ D
Sbjct: 599 RSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDG 658
Query: 245 EEEAAQPQRRPAGGT--GQRRGTAAAPVP 271
E+A P P+G T G R VP
Sbjct: 659 SEKAPAPAPPPSGSTSCGDRDSRRRGAVP 687
Score = 38.1 bits (87), Expect = 0.010
Identities = 53/229 (23%), Positives = 83/229 (36%), Gaps = 54/229 (23%)
Query: 125 AAAPAPTSSGHRTEKRKPQQPQCRPAAGT------GQRRGSG-----------CSPSAD- 166
AA P P +S T + PQ P R G + G G P+AD
Sbjct: 416 AARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADS 475
Query: 167 -------------QQRAQDREEEATAAPVP---TSSGHRTEKRKRLQLQCQPAGGTGQRR 210
Q+R + R+ + AP P ++G T K+ R + + G +
Sbjct: 476 RWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRE---RKRSGEAKEA 532
Query: 211 GSRSSPSRQPA-------------GGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAG 257
S SS QPA ++ GS +S SA R + R ++ RR +
Sbjct: 533 AS-SSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSA---RRRSRSRSRSRSTRRRSR 588
Query: 258 GTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEEG 306
T +RRG + +RR + PA +S+ + +R +G
Sbjct: 589 STDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDG 637
Score = 36.2 bits (82), Expect = 0.037
Identities = 46/221 (20%), Positives = 74/221 (33%), Gaps = 33/221 (14%)
Query: 69 EEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAP 128
E A AAP T KP++ + + G + +G++ + + + R +
Sbjct: 886 EMAKAAPGST---------KPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGG- 935
Query: 129 APTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGH 188
SG + +K + C AAGT + S + A P P
Sbjct: 936 ----SGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPAL--- 988
Query: 189 RTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEA 248
T + + C+ S + G R G+ +++ ++ EEE
Sbjct: 989 -TPDSQTVDSSCKTP--------EVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEE 1039
Query: 249 AQPQRRPAGGTGQRRGTAAAP--VPTTGGTGQRRGTAAAPA 287
QP A T AAAP P+ G T G PA
Sbjct: 1040 QQPATTTATST-----AAAAPSTAPSAGSTAGDSGAEDGPA 1075
Score = 32.7 bits (73), Expect = 0.41
Identities = 57/283 (20%), Positives = 95/283 (33%), Gaps = 47/283 (16%)
Query: 48 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSR 107
G RR + D+ +DR+ + ++ A + P +P G+ S
Sbjct: 767 GSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSC 826
Query: 108 SSSSADQQ---GAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS 164
SS Q RE ++ PA ++ +AG G G S
Sbjct: 827 SSRKVKLQSKVAVLIREGVSSTTPAKDAA----------------SAGLG---SIGVKFS 867
Query: 165 ADQQ------RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSR 218
D++ + +R A P S+ + K K + G G+ + S++
Sbjct: 868 RDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKV 927
Query: 219 QPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGT--------AAAPV 270
+ GG+G GS S + +A + A +G+ R AAP
Sbjct: 928 RSGGGSG---GSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPP 984
Query: 271 P--------TTGGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEE 305
P T + + + P + G R G+EE EEE
Sbjct: 985 PPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEE 1027
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 60.8 bits (146), Expect = 1e-09
Identities = 63/242 (26%), Positives = 87/242 (35%), Gaps = 31/242 (12%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR------R 95
Q +G G R GS SP R + AAA APT E P+ R
Sbjct: 319 QRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR 378
Query: 96 PAGGTG-----QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 150
AGG G +RR RS SSA + R A P +S + R A
Sbjct: 379 AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGA 438
Query: 151 AGTGQRRGSGCSPSADQQRAQD---REEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
G G GS +RA++ R A+ +P P + G R G
Sbjct: 439 PGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR---------------GGP 483
Query: 208 QRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQR--AQDREEEAAQPQRRPAGGTGQRRGT 265
+ + S SP P + R S+S + ++R + R +P R G G+ R +
Sbjct: 484 EGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHS 543
Query: 266 AA 267
A
Sbjct: 544 EA 545
Score = 57.8 bits (138), Expect = 1e-08
Identities = 71/266 (26%), Positives = 101/266 (37%), Gaps = 50/266 (18%)
Query: 79 SRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTE 138
SR + ++++ + ++RP + RR R SS + + + +P+ S HR E
Sbjct: 226 SRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDE 285
Query: 139 KRKPQQPQC------RPAAGTG----QRRG-----SGC-------------SPSADQQRA 170
RK + P+ G+G QR G SG PS+ R
Sbjct: 286 GRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRV 345
Query: 171 QDREEEATAAPVPTSSGHRTEKRKRLQLQ----CQPAGGTGQRRGSRSSPSRQPAGGTGQ 226
+D+ A AAP P + G + + + AGG G+RR R R + +
Sbjct: 346 RDK--AAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAP 403
Query: 227 RRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTT------GGTGQR- 279
RR R P R R A R + +G RG A P P GG G+R
Sbjct: 404 RRRGRRRPRPAPPRGSSRSLSRA----RSSSDSGSGRG-APGPGPEPGSERGHGGHGKRA 458
Query: 280 --RGTAAAPAPTSTGTGQ--RRGSEE 301
R A PA TS G RRG E
Sbjct: 459 KERPPRARPASTSPSPGAHGRRGGPE 484
Score = 41.6 bits (96), Expect = 9e-04
Identities = 58/266 (21%), Positives = 95/266 (35%), Gaps = 37/266 (13%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQ----CQPAGGTGQRRGS---GSS 56
R++ + R R+ R S+ + + +P P+ + + + +G RG+ G
Sbjct: 385 RRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPE 444
Query: 57 PSADQ----QGAQDREEEAAAAPAPTSRGHRTEKRKP----QQPQRRPAGGTGQRRGSRS 108
P +++ G + +E A PA TS R+ + R P SRS
Sbjct: 445 PGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRS 504
Query: 109 SSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQ 168
S + + A+ R + +P+P R + + + A +RR SP ++
Sbjct: 505 PSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRR 564
Query: 169 RAQD------REEEATAAPVP------------TSSGHRTEKRKRLQLQCQPAGGTGQR- 209
R R A P+P SS + T R G R
Sbjct: 565 RDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRS 624
Query: 210 RGSRS---SPSRQPAGGTGQRRGSRS 232
G+RS SPSR P+ R S S
Sbjct: 625 HGTRSRTRSPSRTPSPSYHSRSSSES 650
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 59.7 bits (143), Expect = 3e-09
Identities = 72/304 (23%), Positives = 99/304 (32%), Gaps = 40/304 (13%)
Query: 26 ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTE 85
E T+ P + P+ P + + P+ + A E APAP S HR
Sbjct: 396 EASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS--HREI 453
Query: 86 KRKPQQPQR--------RPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRT 137
P R + T RR RS S A + + R PT GH +
Sbjct: 454 SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR------TPTKRGH-S 506
Query: 138 EKRKPQQPQCRPAAGTG-----QRRGSGCSP------------------SADQQRAQDRE 174
R PQ + R A G QRRG SP SA + R+ R
Sbjct: 507 RSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRS 566
Query: 175 EEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSP 234
+ R R R + + T RR SRS + + R S
Sbjct: 567 PATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR 626
Query: 235 SADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTG 294
+ R + R A+ R T RRG + + P G + R A + + T
Sbjct: 627 TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP 686
Query: 295 QRRG 298
RRG
Sbjct: 687 ARRG 690
Score = 59.3 bits (142), Expect = 4e-09
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 15/258 (5%)
Query: 48 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH-RTEKRKPQQPQRRPAGGTGQRRGS 106
GQR SGSS D + + +E + + +P S+ RT R+ + P + R
Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSP 1593
Query: 107 RSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSAD 166
R S S +D+ AAP S + + K P+ P G PS +
Sbjct: 1594 RRSRSGSSPEVKDKPR---AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 167 QQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQ 226
+ + E G R+ + + + P +RR SRSSP +
Sbjct: 1651 GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP-----RRRSSRSSPELTRKARLSR 1705
Query: 227 R-RGSRSSPSADQQR--AQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTA 283
R R + SSP + R + P+ + +RR +A++P T RRG +
Sbjct: 1706 RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSP---RTKTTSRRGRS 1762
Query: 284 AAPAPTSTGTGQRRGSEE 301
+P P + R E
Sbjct: 1763 PSPKPRGLQRSRSRSRRE 1780
Score = 58.9 bits (141), Expect = 5e-09
Identities = 70/307 (22%), Positives = 116/307 (37%), Gaps = 26/307 (8%)
Query: 16 RESSEGDQWLENE-KTK-PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA 73
+E SE D +++ KT+ PLR + + P + R S S +D+ A
Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
Query: 74 APAPTSRGHRTEKRKPQQPQRRPAGGTGQR------RGSRSSSSADQQGAQDREEE--AA 125
A + + + P+ RR G+ + GS S+ S+ + + R +
Sbjct: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR 1673
Query: 126 AAPAPTSSGHRTEKRKPQQ--PQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVP 183
++P P + +R+ + P+ A +R S S + R R + + P
Sbjct: 1674 SSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP 1733
Query: 184 TSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSP-----------SRQPAGGTGQRRGSRS 232
+ R+R P T RRG SP SR+ T +RR RS
Sbjct: 1734 EPAEKSRSSRRRRSAS-SPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR-DRS 1791
Query: 233 SPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTG 292
S R + R ++ RR GG+G + A + + +RRG + P PTS
Sbjct: 1792 GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP-PTSRK 1850
Query: 293 TGQRRGS 299
+ R S
Sbjct: 1851 RSRSRTS 1857
Score = 55.8 bits (133), Expect = 5e-08
Identities = 77/320 (24%), Positives = 124/320 (38%), Gaps = 30/320 (9%)
Query: 10 TRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDRE 68
T ++ S QW + + + PQ + + QR G S + ++G ++
Sbjct: 499 TPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR 558
Query: 69 EEAAAAPAPTSRGH---RTEKRKPQQPQRRPA-----GGTGQRRGSRSSSSADQQGAQDR 120
+ + +P +RG RT R+ + R PA T RR SRS + A + ++ R
Sbjct: 559 RGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR 618
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS-----ADQQRAQDREE 175
+ + R+ R P + R + T RRG S + + R R
Sbjct: 619 TPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRS 678
Query: 176 EATAAPVPTSSGH---RTEKRKRLQLQCQPAGG-----TGQRRG-SRSSPSRQPAGGTGQ 226
+ + P G RT +R R + + G T QRRG S SS R+ T Q
Sbjct: 679 GRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ 738
Query: 227 RRG-SRSSPSADQQRAQDREEEA-AQPQRRPAGGTGQRRG-TAAAPVP----TTGGTGQR 279
RR S SSP + R R + + P+ + RR + ++P P T R
Sbjct: 739 RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSR 798
Query: 280 RGTAAAPAPTSTGTGQRRGS 299
G++ A + T + R S
Sbjct: 799 SGSSQPKAKSRTPPRRSRSS 818
Score = 55.5 bits (132), Expect = 6e-08
Identities = 64/287 (22%), Positives = 111/287 (38%), Gaps = 32/287 (11%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR 94
P+ P+ +G + + RG S+ + + + ++ A SR K K + P R
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG-SRSSPEPKTKSRTPPR 1687
Query: 95 RPAGGTGQR--------RGSRSSSSADQQGAQD----REEEAAAAPAPTSSGHRTEKRKP 142
R + + R SRS+SS+ + ++ R + ++P P + +R+
Sbjct: 1688 RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747
Query: 143 QQPQCRPAAGTGQRRGSGCSPSA---DQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQ 199
P T RRG SP + R++ R E+ SG +R Q
Sbjct: 1748 ASS---PRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804
Query: 200 CQPAGGTGQRRGSRSSPSRQPA------GGTGQRRGSRSSPSADQQRAQDREEEAA-QPQ 252
+ T +RRG SR PA + +RRG +P ++R++ R A +
Sbjct: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRS 1864
Query: 253 RRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGS 299
R A RR + P+ + RR + + +P S + R S
Sbjct: 1865 RSRASPATHRRSRSRTPLIS------RRRSRSRTSPVSRRRSRSRTS 1905
Score = 54.7 bits (130), Expect = 1e-07
Identities = 67/266 (25%), Positives = 98/266 (36%), Gaps = 49/266 (18%)
Query: 55 SSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGT--GQRRGS----RS 108
SSP D E +++A +P + P+ P RR G+ G R GS R
Sbjct: 1403 SSPVLDAVPRTPSRERSSSASSPEMKDGL-----PRTPSRRSRSGSSPGLRDGSGTPSRH 1457
Query: 109 SSSADQQGAQD---------REEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGS 159
S S G +D E +++ P R R P P+ T QR S
Sbjct: 1458 SLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERS 1517
Query: 160 GCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQ 219
G S DQ+ T A P G R+ +L +P+ +R S SSP +
Sbjct: 1518 GSESSVDQK---------TVARTPL--GQRSRSGSSQELDVKPSASPQERSESDSSPDSK 1566
Query: 220 PAGGTGQRRGSRS--SPSADQQR----AQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTT 273
T R+ SRS SP D + + R + + + +P + G+ ++P P
Sbjct: 1567 AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP-- 1624
Query: 274 GGTGQRRGTAAAPAPTSTGTGQRRGS 299
APAP + R GS
Sbjct: 1625 ----------KAPAPRALPRRSRSGS 1640
Score = 52.8 bits (125), Expect = 4e-07
Identities = 61/287 (21%), Positives = 109/287 (37%), Gaps = 22/287 (7%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
P ++ TR R S + +++ P ++ + + T RRG S + ++
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSR--TPARRGRSRSRTPARR 677
Query: 63 GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG--TGQRRGSRSSSSADQQGAQDR 120
+ R A SR R + + + RR T QRRG SSS + ++
Sbjct: 678 SGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTS 737
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQ---PQCRPAAGTGQRRG-SGCSPSADQQRAQDREEE 176
+ + + +P R R+ + P+ + + RR SG SP Q+
Sbjct: 738 QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS 797
Query: 177 ATAAPVPTSSGHRTEKRKRLQLQCQPAGGT---GQRRGSRSSPSRQPAGGTGQRRGSRSS 233
+ + P + +R R P + ++ S SSP + GT R+GS +S
Sbjct: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857
Query: 234 PSADQQ-----------RAQDREEEAAQPQRRPAGGTGQRRGTAAAP 269
P A++Q + D E ++ P R G+ R ++ P
Sbjct: 858 PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP 904
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/297 (20%), Positives = 113/297 (38%), Gaps = 33/297 (11%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRG-SGSSPSADQ 61
P Q+ T +L E +E +NE+ + + QRR P+ +
Sbjct: 112 PGQRPAVTETHQLAELNEK----KNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEP 167
Query: 62 QGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDRE 121
E++++ +PT + + +K+K + RR + +R +SS + + +
Sbjct: 168 PKPYSLVRESSSSRSPTPK--QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225
Query: 122 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQ-RRGSGCSPSADQQRAQDREEEATAA 180
+ +P P S +K++ + PA + + R + ++ ++ R A A
Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285
Query: 181 PVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGS-------RSS 233
T+ R+ PA G RRG +P +P + QR S SS
Sbjct: 286 THTTALAGRSP---------SPASG---RRGEGDAPFSEPGTTSTQRPSSPETATKQPSS 333
Query: 234 PSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTS 290
P D+ + +E+ A +P P +R T P T +R G + P T+
Sbjct: 334 PYEDKDK-DKKEKSATRPSPSP-----ERSSTGPEPPAPTPLLAERHGGSPQPLATT 384
Score = 48.9 bits (115), Expect = 6e-06
Identities = 68/311 (21%), Positives = 117/311 (37%), Gaps = 37/311 (11%)
Query: 7 EQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQC---QPA--GGTGQRRGSGSSPSADQ 61
E + R R S E P R ++ P +PA + +RR S SSP
Sbjct: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT 1755
Query: 62 QGAQDREEEAAAAPAPTSRG-----HRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQG 116
+ R +P+P RG R+ + K + +RR G+ Q R S +
Sbjct: 1756 TSRRGR------SPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809
Query: 117 AQDREEEAAA----APAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQD 172
R + +PA S + +R+ + + P T ++R + A +R++
Sbjct: 1810 VTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP---TSRKRSRSRTSPAPWKRSRS 1866
Query: 173 REEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSP----SRQPAGGTGQRR 228
R AT S RT R + + + + + +R SR+S SR A +RR
Sbjct: 1867 RASPATHR----RSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR 1922
Query: 229 GSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAP 288
+P ++R++ R + R +RR + P T RR + + +P
Sbjct: 1923 SRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVT------RRRSRSRTSP 1976
Query: 289 TSTGTGQRRGS 299
+ + R S
Sbjct: 1977 ITRRRSRSRTS 1987
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/198 (20%), Positives = 73/198 (36%), Gaps = 4/198 (2%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQR 103
+ G+ GSS + A R AP R R + P + +RR + +
Sbjct: 2555 SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614
Query: 104 RGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSP 163
S SSSS+ + ++++ + +SS + PQ P + ++ G
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR 2674
Query: 164 SADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGG 223
S ++ D ++ + R + + Q + G RRG R SR P
Sbjct: 2675 SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGD-SRSP--- 2730
Query: 224 TGQRRGSRSSPSADQQRA 241
+ +RR SP + R+
Sbjct: 2731 SHKRRRETPSPRPMRHRS 2748
Score = 42.4 bits (98), Expect = 5e-04
Identities = 51/238 (21%), Positives = 86/238 (36%), Gaps = 20/238 (8%)
Query: 63 GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQ---D 119
GAQ AA PA R + + + S SSS+D +G+
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSS--SSSGSSSSDSEGSSLPVQ 2571
Query: 120 REEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATA 179
E P+PT + + R+ + P+ PA +RR S S S+ + +++
Sbjct: 2572 PEVALKRVPSPTPAP-KEAVREGRPPEPTPAKR--KRRSSSSSSSSSSSSSSSSSSSSSS 2628
Query: 180 APVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQR---------RGS 230
+ +SS + PA Q +SP + P G R R S
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688
Query: 231 RSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAP 288
RS + +R + + + + Q+ + G RRG + + +RR +P P
Sbjct: 2689 RSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG---DSRSPSHKRRRETPSPRP 2743
Score = 40.8 bits (94), Expect = 0.002
Identities = 64/297 (21%), Positives = 102/297 (34%), Gaps = 43/297 (14%)
Query: 22 DQWLENEKTKPLRPQQQPQCQPAGGT--------GQRRGSGSSPSADQQGAQDREEEAAA 73
D+ + ++ RP P+ G +R G P A +Q+ +
Sbjct: 337 DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396
Query: 74 APAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTS- 132
A +PT ++ P+ P++ P + + + + A E APAP S
Sbjct: 397 A-SPTR-----DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH 450
Query: 133 ---SGHRTEKRKPQQPQCRPAAGT---GQRRGSGCSPSADQQRAQDREEEATAAPVPTSS 186
S T K + R + + +R G SP A +R + R PT
Sbjct: 451 REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP-ATAKRGRSRSR------TPTKR 503
Query: 187 GHRTEK----RKRLQLQCQPAGGTGQRRGSRSSPSR---------QPAGGTGQRRGSRSS 233
GH + R+ Q + QRRG SP R Q G + R RS
Sbjct: 504 GHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSH 563
Query: 234 PSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPV--PTTGGTGQRRGTAAAPAP 288
+ R + R A+ R + +RR + P + T RRG + + P
Sbjct: 564 SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620
Score = 39.7 bits (91), Expect = 0.003
Identities = 66/307 (21%), Positives = 114/307 (37%), Gaps = 38/307 (12%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
+P+ K + R SS + ++ P + GT R+GS +SP A++
Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANE 862
Query: 62 QGAQDREE---EAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGA- 117
Q + E++ P SR P R + ++ SRSSS + A
Sbjct: 863 QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAI 922
Query: 118 ---QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQR-------RGSGCSPSADQ 167
+ R +++P+P+ RT R+ + P + R GS + +
Sbjct: 923 ISPRQRSHSGSSSPSPSRVTSRTTPRRSR--SVSPCSNVESRLLPRYSHSGSSSPDTKVK 980
Query: 168 QRAQDREE-----------EATAAPVPTSSGHRT----EKRKRLQLQCQPAGGTGQRRGS 212
R+ +A P P+ SG ++ EK K +Q P G G
Sbjct: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCP-GSLSLCAGV 1039
Query: 213 RSS-PSRQPAGGTG--QRRG-SRSSPS--ADQQRAQDREEEAAQPQRRPAGGTGQRRGTA 266
+SS P + G Q +G S++SP +D + R+ + P + T + G +
Sbjct: 1040 KSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRS 1099
Query: 267 AAPVPTT 273
+ P T
Sbjct: 1100 RSSSPVT 1106
Score = 37.4 bits (85), Expect = 0.017
Identities = 44/232 (18%), Positives = 80/232 (34%), Gaps = 17/232 (7%)
Query: 37 QQPQC----QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 92
QQP QPA +RR S SS S+ + ++++ + +S P QP
Sbjct: 2516 QQPSALAALQPAK---ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQP 2572
Query: 93 Q----RRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR 148
+ R P+ + R + A+ + ++++ + +SS +
Sbjct: 2573 EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632
Query: 149 PAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKR-----LQLQCQPA 203
++ + S S S + + A+P G R + R L+ +
Sbjct: 2633 SSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLS 2692
Query: 204 GGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRP 255
+RR PS + + RGSR D R+ + P RP
Sbjct: 2693 YSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGD-SRSPSHKRRRETPSPRP 2743
Score = 32.3 bits (72), Expect = 0.54
Identities = 31/159 (19%), Positives = 51/159 (32%), Gaps = 23/159 (14%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
+P + R R+ SS + + + + S SSPS +
Sbjct: 2594 RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653
Query: 62 QGAQ--------------DREEEAAAAPAPTSRGHRT------EKRKPQ-QPQRRPAGGT 100
G Q +R + P + R R+ E+R+P QP R +
Sbjct: 2654 PGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSS 2713
Query: 101 GQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEK 139
RGSR D + + +P P HR+ +
Sbjct: 2714 SSERGSRRGQRGDSRSPSHKRRRETPSPRPMR--HRSSR 2750
Score = 32.0 bits (71), Expect = 0.70
Identities = 61/290 (21%), Positives = 101/290 (34%), Gaps = 24/290 (8%)
Query: 10 TRLRKLRESSEGDQWLENEKTKPL-RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE 68
TR R +S + +T P+ R + + + PA +RR +P ++ ++ R
Sbjct: 1990 TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAI---RRRSRSRTPLLPRKRSRSRS 2046
Query: 69 -----EEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEE 123
+ + T+RG R+ R P +RR A G+ R ++ A + + R
Sbjct: 2047 PLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPP 2106
Query: 124 AAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVP 183
A + S R +CR + G + GS +P + Q+A + +P
Sbjct: 2107 VALNSSRMSCFSRPSMSPTPLDRCR-SPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP 2165
Query: 184 ---TSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQR 240
+S + R+ L T G+ P A G R +P
Sbjct: 2166 DHQRTSVPENHAQSRIALAL-----TAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL 2220
Query: 241 AQDREEEAAQPQRRPAGGTGQRRGTAAA---PVPTTGGTGQRRGTAAAPA 287
R AA R + A+A +PT R AAA A
Sbjct: 2221 ---RTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAA 2267
Score = 31.6 bits (70), Expect = 0.92
Identities = 31/168 (18%), Positives = 61/168 (36%), Gaps = 10/168 (5%)
Query: 26 ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTE 85
E +P +++ + + + S SS S+ + ++++ + +S +
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Query: 86 KRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQ-Q 144
+ Q +PA G R S S R+ + + + S E+R+P Q
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRS-------PRKPIDSLRDSRSLSYSPVERRRPSPQ 2704
Query: 145 PQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEK 192
P R + RGS D + + T +P P HR+ +
Sbjct: 2705 PSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR--HRSSR 2750
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 58.2 bits (139), Expect = 9e-09
Identities = 70/324 (21%), Positives = 114/324 (35%), Gaps = 33/324 (10%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPL------RPQQQPQCQPAGG-TGQRRGSGS 55
PR + TR + +S +G + + +P R Q Q + AG T +R+GS
Sbjct: 1537 PRSASRQTRNEE--QSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSV 1594
Query: 56 SPSADQQGAQDREEEAAAAPAPTSRGHRTEK-----RKPQQPQRRPAGGTGQRRGSRSSS 110
S D +G + E + + + G E+ R P+ Q A SR S
Sbjct: 1595 SQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSG 1654
Query: 111 SADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRR-----GSGCSPSA 165
+ + + + ++ A +S G R R Q +GTG+R+ G + +
Sbjct: 1655 TRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGS 1714
Query: 166 DQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG---------SRSSP 216
+A D E + + + S H + Q G +G+R G S
Sbjct: 1715 SGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQ 1774
Query: 217 SRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAA-----PVP 271
S G TG G R +Q R R + + Q G G RG V
Sbjct: 1775 SESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVD 1834
Query: 272 TTGGTGQRRGTAAAPAPTSTGTGQ 295
++G +G + + GQ
Sbjct: 1835 SSGHSGSHHSHTTSQERSDVSRGQ 1858
Score = 57.0 bits (136), Expect = 2e-08
Identities = 58/264 (21%), Positives = 93/264 (35%), Gaps = 30/264 (11%)
Query: 34 RPQQQPQCQPAGGTGQRRGS---GSSPSADQQGAQDREEEAAAAPAPTSR--GHRTEKRK 88
R QQ GTG+R+ S G S + G+Q + E + + T H
Sbjct: 1684 RHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPH 1743
Query: 89 PQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR 148
Q Q G +G+R G RS S Q ++ E A P++ G + + + + R
Sbjct: 1744 QQSHQESTRGQSGERSG-RSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSR 1802
Query: 149 --------------PAAGTGQRRGSGCSPSADQQ----------RAQDREEEATAAPVPT 184
P + G R+GS S D +Q+R + +
Sbjct: 1803 HSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR 1862
Query: 185 SSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDR 244
S +T K+ + +G SR+ SR G GQ G R+S + +QD
Sbjct: 1863 SVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDS 1922
Query: 245 EEEAAQPQRRPAGGTGQRRGTAAA 268
+ + G+ R +A
Sbjct: 1923 DSQGHSEDSERWSGSASRNHLGSA 1946
Score = 52.4 bits (124), Expect = 5e-07
Identities = 66/293 (22%), Positives = 100/293 (34%), Gaps = 39/293 (13%)
Query: 42 QPAGGTGQRRGSGSSP---SADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAG 98
Q A TG R+GS S+ +QD ++ P +SRG R Q R
Sbjct: 1457 QTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPG-SSRGGRQGSYHEQSVDRSGHS 1515
Query: 99 G--------TGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 150
G G+ S S Q R EE + + S E
Sbjct: 1516 GYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQ 1575
Query: 151 AGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ-- 208
G G+ GS S +QDR+ E GH + +R + + G+ +
Sbjct: 1576 VGQGESAGSKTSRRQGSSVSQDRDSE----------GHSEDSERRSESASRNHYGSAREQ 1625
Query: 209 -RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTA- 266
R GSR+ S Q + S S + +AA Q + G+R G+
Sbjct: 1626 SRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRH 1685
Query: 267 --AAPVPTTGGTGQR-----------RGTAAAPAPTSTGTGQRRGSEEMEEEG 306
+A T GTG+R RG++ + A S G + ++ + G
Sbjct: 1686 QQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHG 1738
Score = 50.8 bits (120), Expect = 1e-06
Identities = 64/292 (21%), Positives = 103/292 (35%), Gaps = 53/292 (18%)
Query: 8 QDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQD 66
++ ++ + SS+G + +++ Q P + T +RRGS S D +G ++D
Sbjct: 252 EENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESR--TRKRRGSRVSQDRDSEGHSED 309
Query: 67 REEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAA 126
E + +A SR H + + R + R S S+ + + R E ++
Sbjct: 310 SERHSGSA----SRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSS 365
Query: 127 APAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQR----------------- 169
T+S H + P G+R GSG SAD R
Sbjct: 366 R-GQTASSHEQARSSP-----------GERHGSGHQQSADSSRHSATGRGQASSAVSDRG 413
Query: 170 --------AQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPA 221
A D E + + + SGH ++ Q G +G+R G S Q +
Sbjct: 414 HRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVS 473
Query: 222 ---------GGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRG 264
G TG G R +Q R R + + Q G G RG
Sbjct: 474 THEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRG 525
Score = 50.8 bits (120), Expect = 1e-06
Identities = 61/287 (21%), Positives = 103/287 (35%), Gaps = 25/287 (8%)
Query: 34 RPQQQPQCQPAGG-TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEK-----R 87
R Q Q Q G T +R+GS S +D +G + E + + + RG E+ R
Sbjct: 924 RHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSR 983
Query: 88 KPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQC 147
P+ AG SR S + + + + ++ A +S G R R Q
Sbjct: 984 HPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 1043
Query: 148 RPAAGTGQRRGSGCSPSADQ-----QRAQDREEEATAAPVPTSSGHRTE---KRKRLQLQ 199
+G +R+ S + +A D E + + + SGH + ++ +
Sbjct: 1044 SRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESA 1103
Query: 200 CQPAGGTGQRRGS----------RSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAA 249
+GG R GS S + TG+R+GS + D R +E
Sbjct: 1104 RDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQD 1163
Query: 250 QPQRRPAGGTGQRRGT-AAAPVPTTGGTGQRRGTAAAPAPTSTGTGQ 295
+ P G R+G+ V +G +G + + GQ
Sbjct: 1164 TIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ 1210
Score = 49.3 bits (116), Expect = 4e-06
Identities = 55/263 (20%), Positives = 93/263 (35%), Gaps = 30/263 (11%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGS---SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKP- 89
R QQ G G R+ S + S G+Q E + + T + P
Sbjct: 1360 RHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPH 1419
Query: 90 QQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR- 148
QQ + A G RS S Q + ++ E AP++ G + + + + R
Sbjct: 1420 QQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRH 1479
Query: 149 -------------PAAGTGQRRGSGCSPSADQQ----------RAQDREEEATAAPVPTS 185
P + G R+GS S D+ Q R + + P S
Sbjct: 1480 SASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRS 1539
Query: 186 SGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDRE 245
+ +T ++ + +G +R+ SR G G+ GS++S +QDR+
Sbjct: 1540 ASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRD 1599
Query: 246 EE--AAQPQRRPAGGTGQRRGTA 266
E + +RR + G+A
Sbjct: 1600 SEGHSEDSERRSESASRNHYGSA 1622
Score = 47.4 bits (111), Expect = 2e-05
Identities = 49/254 (19%), Positives = 91/254 (35%), Gaps = 31/254 (12%)
Query: 51 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSS 110
RGS S ++D +G + + + + GH + Q Q G +G+R G RS S
Sbjct: 415 RGSSGSQASDSEGHSENSDTQSVS------GHGKAGLRQQSHQESTRGRSGERSG-RSGS 467
Query: 111 SADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR--------------PAAGTGQR 156
S Q ++ + A ++ G + + + R P + G R
Sbjct: 468 SLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGR 527
Query: 157 RGSGCSPSADQQ----------RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGT 206
+GS S ++ +Q R + + S+ +T ++ + +G
Sbjct: 528 QGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSR 587
Query: 207 GQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTA 266
S++ SR G GQ G R+S + +QD + + G+ R
Sbjct: 588 HHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHG 647
Query: 267 AAPVPTTGGTGQRR 280
+A + G+ R
Sbjct: 648 SAQEQSRDGSRHPR 661
Score = 47.4 bits (111), Expect = 2e-05
Identities = 61/284 (21%), Positives = 99/284 (34%), Gaps = 30/284 (10%)
Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGS 106
+ ++ G+ + S+ A E+A ++P G R R Q G G R+ S
Sbjct: 1325 SSRQSGTHHTESSSHGQAVSSHEQARSSP-----GERHGSRHQQSADSSRHSGIGHRQAS 1379
Query: 107 ---RSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSP 163
R S G+Q E + + T S + P Q + +A SG S
Sbjct: 1380 SAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSR 1439
Query: 164 SADQQRAQDREEEATAAPVPTSSGHRTEKRKRL---------------QLQCQPAGGTGQ 208
S Q + + E+T S+G R R ++ P G
Sbjct: 1440 SFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGG 1499
Query: 209 RRGSRSSPSRQPAGGTGQRRGSRSSPS--ADQQRAQDREEEAA-QPQRRPAGGTGQRRGT 265
R+GS S +G +G S ++P +D Q A+ Q + G G R
Sbjct: 1500 RQGSYHEQSVDRSGHSGYHH-SHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSG 1558
Query: 266 AAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRG---SEEMEEEG 306
+ P+T R + T +R+G S++ + EG
Sbjct: 1559 SRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEG 1602
Score = 46.6 bits (109), Expect = 3e-05
Identities = 58/256 (22%), Positives = 82/256 (32%), Gaps = 32/256 (12%)
Query: 45 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
G + RG S SA +Q R +E + + S H E R G GQ
Sbjct: 3471 GRSDASRGQSGSRSASRQ---TRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSA 3527
Query: 105 GSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS 164
G R+S + +QD + S GH + + + + RGS S
Sbjct: 3528 GPRTSRNQGSSVSQDSD----------SQGHSEDSER------WSGSASRNHRGSAQEQS 3571
Query: 165 ADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGT 224
D R E A GH E + Q G +S Q
Sbjct: 3572 RDGSRHPTSHHEDRA-----GHGHSAESSR----QSGTHHAENSSGGQAASSHEQARSSA 3622
Query: 225 GQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAA 284
G+R GS SAD R A R +G RG++ + + G + T +
Sbjct: 3623 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSG----HRGSSGSQASDSEGHSEDSDTQS 3678
Query: 285 APAPTSTGTGQRRGSE 300
A G Q+ E
Sbjct: 3679 VSAHGQAGPHQQSHQE 3694
Score = 46.2 bits (108), Expect = 4e-05
Identities = 47/242 (19%), Positives = 85/242 (35%), Gaps = 33/242 (13%)
Query: 51 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSS 110
RGS S ++D +G + + + + + H QQ + G R RS S
Sbjct: 3657 RGSSGSQASDSEGHSEDSDTQSVSAHGQAGPH-------QQSHQESTRGRSAGRSGRSGS 3709
Query: 111 SADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR--------------PAAGTGQR 156
Q ++ E A P++ G + + + + R P + G R
Sbjct: 3710 FLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGR 3769
Query: 157 RGSGCSPSADQQ----------RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGT 206
+GS S D+ +Q R + + S+ T ++ + +G
Sbjct: 3770 QGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSR 3829
Query: 207 GQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEA--AQPQRRPAGGTGQRRG 264
+++ SR G G+ GSR S +QD + EA +RR + G
Sbjct: 3830 HHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHG 3889
Query: 265 TA 266
++
Sbjct: 3890 SS 3891
Score = 44.7 bits (104), Expect = 1e-04
Identities = 51/258 (19%), Positives = 85/258 (32%), Gaps = 32/258 (12%)
Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGS 106
+G R SGS S + ++D + ++ +A QQ + A G
Sbjct: 2034 SGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAG--------PHQQSHKESARGQSGESSG 2085
Query: 107 RSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR--------------PAAG 152
RS S Q ++ E AP++ G + Q R P
Sbjct: 2086 RSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPS 2145
Query: 153 TGQRRGSGCSPSADQQ----------RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQP 202
G R+GS S D+ +Q R + + S+ +T +++ +
Sbjct: 2146 RGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRH 2205
Query: 203 AGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQR 262
+G S + SR G GQ G R+S +QD + E G+ R
Sbjct: 2206 SGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASR 2265
Query: 263 RGTAAAPVPTTGGTGQRR 280
+A + G+ R
Sbjct: 2266 NHHGSAQEQSRDGSRHPR 2283
Score = 43.9 bits (102), Expect = 2e-04
Identities = 63/293 (21%), Positives = 92/293 (31%), Gaps = 57/293 (19%)
Query: 36 QQQPQCQPAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAPTSRGHRTE 85
Q + P G R+GS S D+ G +Q R + + S +T
Sbjct: 1162 QDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 1221
Query: 86 KRKPQQPQRRPAG------------------GTGQRRGSRSSSSADQQGAQDREEEAAAA 127
K K R +G G Q GSR+S +QD + E +
Sbjct: 1222 KDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSD 1281
Query: 128 PAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSG 187
+ SG + + GS S D R +E A S G
Sbjct: 1282 DSERLSG----------------SASRNHHGSSREQSRDGSRHPGFHQEDRA-----SHG 1320
Query: 188 HRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEE 247
H + ++ + GQ S P G+R GSR SAD R
Sbjct: 1321 HSADSSRQSGTHHTESSSHGQAVSSHEQARSSP----GERHGSRHQQSADSSRHSGIGHR 1376
Query: 248 AAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSE 300
A R +G RG++ + V + G + T + A G Q+ E
Sbjct: 1377 QASSAVRDSG----HRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKE 1425
Score = 43.5 bits (101), Expect = 2e-04
Identities = 62/289 (21%), Positives = 100/289 (34%), Gaps = 29/289 (10%)
Query: 34 RPQQQPQCQPAGGTGQRR-GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEK-----R 87
R Q Q Q G RR GS S +D +G + E + + + RG E+ R
Sbjct: 3193 RHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSR 3252
Query: 88 KPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQC 147
P+ AG SR S + + + + ++ A +S G R R Q
Sbjct: 3253 HPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 3312
Query: 148 RPAAGTGQRRGSGCSPSADQQ-------RAQDREEEATAAPVPTSSGHRT---EKRKRLQ 197
+ +G RG S D + +A D E + + + SGH ++ +
Sbjct: 3313 --SRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQE 3370
Query: 198 LQCQPAGGTGQRRGS----------RSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEE 247
+GG R GS S + TG+R+GS + D R +E
Sbjct: 3371 SARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEG 3430
Query: 248 AAQPQRRPAGGTGQRRGT-AAAPVPTTGGTGQRRGTAAAPAPTSTGTGQ 295
+ P R+G+ V +G +G + + GQ
Sbjct: 3431 QDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 3479
Score = 42.7 bits (99), Expect = 4e-04
Identities = 56/229 (24%), Positives = 73/229 (31%), Gaps = 40/229 (17%)
Query: 45 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
G + RG S SA + R EE + + S E R G GQ
Sbjct: 878 GRSDASRGQSGSRSASRT---TRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSE 934
Query: 105 GSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEK-RKPQQPQCR-----PAAGTGQRRG 158
GSR+S +QD + E + + SG + R Q Q R P + R G
Sbjct: 935 GSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAG 994
Query: 159 SGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSR 218
G S + +Q E TSSG G +S
Sbjct: 995 HGHSADSSRQSGTPHAE--------TSSG-----------------------GQAASSHE 1023
Query: 219 QPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAA 267
Q G+R GSR SAD R A R +G G A+
Sbjct: 1024 QARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQAS 1072
Score = 42.4 bits (98), Expect = 5e-04
Identities = 53/263 (20%), Positives = 99/263 (37%), Gaps = 20/263 (7%)
Query: 51 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSS 110
RG S +QG+ + + + + H T + + G +G R SR +
Sbjct: 517 RGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASH----GQSGSRSASRQTR 572
Query: 111 SADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQ-R 169
+ +Q G R + A + + + Q P T + +GS S +D Q
Sbjct: 573 NEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPR--TSRNQGSSVSQDSDSQGH 630
Query: 170 AQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRG 229
++D E + +A + + H + + + P R G S GT +
Sbjct: 631 SEDSERWSGSA---SRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQN 687
Query: 230 SRSSPSA---DQQRAQDREEEAAQPQRRPAGGT---GQRRGTAAAPVPTTGGTGQRRGTA 283
S S +A +Q R+ E ++ Q + A + G G A++ V +G RG++
Sbjct: 688 SSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSG----HRGSS 743
Query: 284 AAPAPTSTGTGQRRGSEEMEEEG 306
+ A S G + ++ + G
Sbjct: 744 GSQATDSEGHSEDSDTQSVSGHG 766
Score = 42.4 bits (98), Expect = 5e-04
Identities = 55/259 (21%), Positives = 92/259 (35%), Gaps = 30/259 (11%)
Query: 34 RPQQQPQCQPAGG-TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 92
R Q Q Q +G T + +GS S +D + D E + + SR H R+ +
Sbjct: 1248 RHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGS---ASRNHHGSSREQSRD 1304
Query: 93 QRRPAGGTGQRRGSR--SSSSADQQGAQDREEEA------AAAPAPTSSGHRTEKRKPQQ 144
R G + R S S+ S+ Q G E + + A +S G R R Q
Sbjct: 1305 GSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQS 1364
Query: 145 PQCRPAAGTGQR-----------RGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKR 193
+G G R RGS S + + + + + + + H+ +
Sbjct: 1365 ADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHK 1424
Query: 194 KRLQLQCQPAGGTGQ-------RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREE 246
+ + Q + G + S Q A TG R+GSR + + R ++
Sbjct: 1425 ESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQD 1484
Query: 247 EAAQPQRRPAGGTGQRRGT 265
+ P G R+G+
Sbjct: 1485 GQDTIRGHPGSSRGGRQGS 1503
Score = 42.4 bits (98), Expect = 5e-04
Identities = 62/278 (22%), Positives = 90/278 (32%), Gaps = 41/278 (14%)
Query: 43 PAGGTGQRRGSGSSPSADQQG--AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGT 100
P +G R+GS D+ G + + S GH + +Q + G
Sbjct: 2466 PGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGD 2525
Query: 101 GQRR-GSR---SSSSADQQGAQDREEEAAAAPAPT------------SSGHRTEKRKPQQ 144
G R GSR +SS AD G + + P + S GH + +
Sbjct: 2526 GSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSG 2585
Query: 145 PQCRPAAGTGQR--RGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQP 202
R G+ Q R P + Q+ DR +A SG R Q
Sbjct: 2586 SASRNHHGSAQEQLRDGSRHPRSHQE---DRAGHGHSADSSRQSGTR---------HTQT 2633
Query: 203 AGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQR 262
+ G G +S Q G+R GS SAD R A R +G
Sbjct: 2634 SSG-----GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG----H 2684
Query: 263 RGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSE 300
RG + + G + T + A G+ Q+ E
Sbjct: 2685 RGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQE 2722
Score = 42.4 bits (98), Expect = 5e-04
Identities = 69/298 (23%), Positives = 101/298 (33%), Gaps = 81/298 (27%)
Query: 45 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
G +G R S ++ + +Q G R + A T H R Q Q + G RR
Sbjct: 3154 GQSGSRSASRTTRNEEQSGDSSRHSVSRHHEAST---HADISRHSQAVQGQSEGSRRSRR 3210
Query: 105 -GSRSSSSADQQG-AQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR-PAAGTGQRRGSGC 161
GS S +D +G ++D E + +A S HR ++ + R P + R G G
Sbjct: 3211 QGSSVSQDSDSEGHSEDSERWSGSA----SRNHRGSVQEQSRHGSRHPRSHHEDRAGHGH 3266
Query: 162 SPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPA 221
S DR ++ TSSG G +S Q
Sbjct: 3267 SA--------DRSRQSGTRHAETSSG-----------------------GQAASSHEQAR 3295
Query: 222 GGTGQRRGSRSSPSADQQR-------------------------AQDREEEAAQPQRRPA 256
G+R GSR SAD R A D E + + +
Sbjct: 3296 SSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSV 3355
Query: 257 GGTGQ----RRGTAAAPVPTTGGTGQRRG-----------TAAAPAPTSTGTGQRRGS 299
G GQ ++ + +GG R G + +A T T TG+R+GS
Sbjct: 3356 SGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGS 3413
Score = 42.0 bits (97), Expect = 7e-04
Identities = 57/277 (20%), Positives = 96/277 (34%), Gaps = 30/277 (10%)
Query: 47 TGQRRGSGSSPSADQQGA--QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
T Q R S + + A Q R EE + S E R G GQ
Sbjct: 550 TSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSS 609
Query: 105 GSRSSSSADQQGAQDREEEAAAAPAPTSSG------HRTEKRKPQQPQCRPAAGTGQRRG 158
G R+S + +QD + + + + SG H + + + + P + R G
Sbjct: 610 GPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAG 669
Query: 159 SGCSPSADQ-------QRAQDREEEATAAPVPTSSGHRTEKRKRLQ-LQCQPAGGTGQRR 210
G S + + Q + + ++ +S+G R R +LQ GTG +
Sbjct: 670 HGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQ 729
Query: 211 --------GSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQR 262
G R S Q G S + + +A ++ + R +G +R
Sbjct: 730 ASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRR 789
Query: 263 RGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGS 299
G+ V T + + ++ T TG R+GS
Sbjct: 790 SGSFLYQVST------HKQSESSHGWTGPSTGVRQGS 820
Score = 41.6 bits (96), Expect = 9e-04
Identities = 56/256 (21%), Positives = 81/256 (31%), Gaps = 32/256 (12%)
Query: 45 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
G + RG S SA ++ ++E + + S H E R G GQ
Sbjct: 2175 GRSDASRGQSGSRSASRK---TYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSS 2231
Query: 105 GSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS 164
G R+S +QD + E GH + + R + + GS S
Sbjct: 2232 GPRTSRPRGSSVSQDSDSE----------GHSEDSER------RSGSASRNHHGSAQEQS 2275
Query: 165 ADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGT 224
D R E A GH E + Q G +S Q
Sbjct: 2276 RDGSRHPRSHHEDRAG-----HGHSAESSR----QSGTHHAENSSGGQAASSHEQARSSA 2326
Query: 225 GQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAA 284
G+R GS SAD R A R +G RG++ + + G + T +
Sbjct: 2327 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSG----HRGSSGSQASDSEGHSEDSDTQS 2382
Query: 285 APAPTSTGTGQRRGSE 300
A G Q+ E
Sbjct: 2383 VSAHGQAGPHQQSHQE 2398
Score = 41.2 bits (95), Expect = 0.001
Identities = 55/244 (22%), Positives = 84/244 (34%), Gaps = 22/244 (9%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTG 101
Q G GQ +G + Q+ A+DR E + T K+ G TG
Sbjct: 760 QSVSGHGQ---AGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSH-----GWTG 811
Query: 102 QRRGSRSSSSADQQGAQDREEEAAAAPAP-TSSGHRTEKRKPQQPQCRPAAGTGQRRG-- 158
G R S +Q A+D +A+ T GH R+ +Q G+ +
Sbjct: 812 PSTGVRQGSHHEQ--ARDNSRHSASQDGQDTIRGHPGSSRRGRQ-------GSHHEQSVD 862
Query: 159 -SGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQ-CQPAGGTGQRRGSRSSP 216
SG S S +A+ + S RT + + + +G S +
Sbjct: 863 RSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADI 922
Query: 217 SRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGT 276
SR G GQ GSR+S +QD + E G+ R +A + G+
Sbjct: 923 SRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGS 982
Query: 277 GQRR 280
R
Sbjct: 983 RHPR 986
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/231 (20%), Positives = 81/231 (35%), Gaps = 23/231 (9%)
Query: 52 GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGS----- 106
GS S ++D +G + + + + H+ + Q+ R +GG R GS
Sbjct: 1065 GSSGSQASDSEGHSEESDTQSVSGHGQDGPHQ---QSHQESARDWSGGRSGRSGSFIYQV 1121
Query: 107 -----RSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGC 161
S+ + + R + + A SS H + + P + G R+GS
Sbjct: 1122 STHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHH 1181
Query: 162 SPSADQQ----------RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
S D+ +Q R + + S+ +T K K+ + +G
Sbjct: 1182 EQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAA 1241
Query: 212 SRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQR 262
S + SR G Q GSR+S +QD + E G+ R
Sbjct: 1242 SWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASR 1292
Score = 40.0 bits (92), Expect = 0.003
Identities = 61/295 (20%), Positives = 100/295 (33%), Gaps = 31/295 (10%)
Query: 43 PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRG---------HRTEKRKPQQPQ 93
P R G G S + +Q E ++ A +S H + +
Sbjct: 1957 PGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADS 2016
Query: 94 RRPAG-GTGQRRGS-RSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAA 151
R +G G GQ + R S G+Q + E + + T S K P Q + +A
Sbjct: 2017 SRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESA 2076
Query: 152 GTGQRRGSGCSPSADQQRAQDREEEAT---AAP------------VPTSSGHRTEKRKRL 196
SG S S Q + + E+T +AP SS H + +
Sbjct: 2077 RGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQD 2136
Query: 197 QLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPS-ADQQRAQDREEEAA-QPQRR 254
++ P G R+GS S +G +G +S +D R Q A+ + +
Sbjct: 2137 TIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDK 2196
Query: 255 PAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRG---SEEMEEEG 306
G G R + ++ R + T + RG S++ + EG
Sbjct: 2197 EQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEG 2251
Score = 40.0 bits (92), Expect = 0.003
Identities = 57/258 (22%), Positives = 89/258 (34%), Gaps = 43/258 (16%)
Query: 45 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
G +G R S ++ + +Q G R + A T H R Q Q + G RR
Sbjct: 2830 GQSGSRSASRTTRNEEQSGDGSRHSGSRHHEAST---HADISRHSQAVQGQSEGSRRSRR 2886
Query: 105 -GSRSSSSADQQG-AQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCS 162
GS S +D +G ++D E + +A + + H + + + + P + R G G S
Sbjct: 2887 QGSSVSQDSDSEGHSEDSERWSGSA---SRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHS 2943
Query: 163 PSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAG 222
+ +Q + TSSG G +S Q
Sbjct: 2944 ADSSRQSGTRHTQ--------TSSG-----------------------GQAASSHEQARS 2972
Query: 223 GTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGT 282
G+R GS SAD R A R +G RG + + G + T
Sbjct: 2973 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG----HRGYSGSQASDNEGHSEDSDT 3028
Query: 283 AAAPAPTSTGTGQRRGSE 300
+ A G+ Q+ E
Sbjct: 3029 QSVSAHGQAGSHQQSHQE 3046
Score = 38.9 bits (89), Expect = 0.006
Identities = 54/264 (20%), Positives = 89/264 (33%), Gaps = 44/264 (16%)
Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGS 106
+G R SGS S ++ ++D + ++ +A H Q Q G +G+ G
Sbjct: 2682 SGHRGYSGSQASDNEGHSEDSDTQSVSA-------HGQAGSHQQSHQESARGRSGETSG- 2733
Query: 107 RSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR--------------PAAG 152
S S Q ++ E + P++ G + + + Q R P +
Sbjct: 2734 HSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSS 2793
Query: 153 TGQRRG---------SGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPA 203
G R+G SG S S +A+ + S RT + + + +
Sbjct: 2794 RGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE------EQS 2847
Query: 204 GGTGQRRGSR-------SSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPA 256
G + GSR + SR GQ GSR S +QD + E
Sbjct: 2848 GDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERW 2907
Query: 257 GGTGQRRGTAAAPVPTTGGTGQRR 280
G+ R +A G+ R
Sbjct: 2908 SGSASRNHHGSAQEQLRDGSRHPR 2931
Score = 38.9 bits (89), Expect = 0.006
Identities = 48/207 (23%), Positives = 70/207 (33%), Gaps = 32/207 (15%)
Query: 47 TGQRRGSGSSPSADQQGA--QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
T Q R S + + A + R EE + + S E R G G+
Sbjct: 3792 TSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESA 3851
Query: 105 GSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS 164
GSR S +QD + EA P+ + R + + GS S
Sbjct: 3852 GSRRSRRQGSSVSQDSDSEA----------------YPEDSERRSESASRNHHGSSREQS 3895
Query: 165 ADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGT 224
D R TA+ V +S Q T + G SS S+ A +
Sbjct: 3896 RDGSRHPGSSHRDTASHVQSS-------------PVQSDSSTAKEHGHFSSLSQDSAYHS 3942
Query: 225 G-QRRGSRSSPSADQQRAQDREEEAAQ 250
G Q RGS S S+ +++ E + Q
Sbjct: 3943 GIQSRGSPHSSSSYHYQSEGTERQKGQ 3969
Score = 38.5 bits (88), Expect = 0.008
Identities = 60/324 (18%), Positives = 103/324 (31%), Gaps = 47/324 (14%)
Query: 18 SSEGDQWL----ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA 73
S + ++W N + + P R G G S + +Q E ++
Sbjct: 3549 SEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSG 3608
Query: 74 APAPTSRG---------HRTEKRKPQQPQRRPAGGTGQRRGS-RSSSSADQQGAQDREEE 123
A +S H + ++ R G GQ + R S G+Q + E
Sbjct: 3609 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE 3668
Query: 124 AAAAPAPTSSGHRTEKRKP-QQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPV 182
+ + T S + P QQ G R Q ++ E A
Sbjct: 3669 GHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAG 3728
Query: 183 PTSSGHRTEKRKRLQ--------------LQCQPAGGTGQRRGSRSSPSRQPAGGTGQRR 228
P++ G + + ++ + ++ P G R+GS S +G +G
Sbjct: 3729 PSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHH 3788
Query: 229 GSRSSPS-ADQQRAQDREEEAAQPQR-RPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAP 286
+S +D Q A++ R G G R +G R A+
Sbjct: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRH------------SGSRHHEASTQ 3836
Query: 287 APTS----TGTGQRRGSEEMEEEG 306
A +S +G G+ GS +G
Sbjct: 3837 ADSSRHSQSGQGESAGSRRSRRQG 3860
Score = 38.1 bits (87), Expect = 0.010
Identities = 47/236 (19%), Positives = 76/236 (32%), Gaps = 13/236 (5%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTG 101
Q G+R GS SAD A++ SR + + +
Sbjct: 3293 QARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDT 3352
Query: 102 QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQC---RPAAGTGQRRG 158
Q + QQ Q+ + + + S + +Q + R TG+R+G
Sbjct: 3353 QSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQG 3412
Query: 159 SGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSR 218
S + D R +E S R + + +G +G +S R
Sbjct: 3413 SHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGR 3472
Query: 219 QPA--GGTGQRRGSRSSPSADQ-----QRAQDREEEA---AQPQRRPAGGTGQRRG 264
A G +G R SR + + +Q + + EA A R G GQ G
Sbjct: 3473 SDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAG 3528
Score = 35.4 bits (80), Expect = 0.064
Identities = 57/269 (21%), Positives = 93/269 (34%), Gaps = 38/269 (14%)
Query: 50 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRG---------HRTEKRKPQQPQRRPAGGT 100
R G G S + +Q E ++ A +S H + ++ R G
Sbjct: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2348
Query: 101 GQRRGS-RSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRG- 158
GQ + R S G+Q + E + + T S + P Q Q + G+ G
Sbjct: 2349 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQ-QSHQESTRGRSAGR 2407
Query: 159 SGCSPSADQQRAQDREEEATAAPVPTSSG---------------HRTEKRKRLQLQCQPA 203
SG S S Q + + E+ TS+G H T + + + P
Sbjct: 2408 SGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPG 2467
Query: 204 GGTGQRRGS-------RSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPA 256
+G R+GS RS S T + S +S R+ R+ + +
Sbjct: 2468 SSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGS 2527
Query: 257 GGTGQRRGTAAAPVPTTG----GTGQRRG 281
+G R A++ ++G G GQ G
Sbjct: 2528 RHSGSRHHEASSRADSSGHSQVGQGQSEG 2556
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 56.6 bits (135), Expect = 3e-08
Identities = 82/332 (24%), Positives = 128/332 (38%), Gaps = 55/332 (16%)
Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72
RK E S + + + P +P + + S S ++ D E + +
Sbjct: 158 RKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS 217
Query: 73 AAPAPTSRGHRTEKRKPQQPQRRPAGG-----TGQRRGS-----------RSSSSADQQG 116
PA + K P + + PA G T Q +G S + ++G
Sbjct: 218 VKPAQVKASSVSTKESPAR-KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG 276
Query: 117 AQDREEEAAAAPAPTSSGHR-TEKRKPQQPQCRPAAGTGQRRGSGCSPS--------ADQ 167
++ EE APA T S + +EK + PA GT G G +P+ A Q
Sbjct: 277 SESEEE----APAGTRSQVKASEKILQVRAASAPAKGTP---GKGATPAPPGKAGAVASQ 329
Query: 168 QRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQ-------- 219
+A EE++ ++ +S + LQ + +G T Q G+ S+P+++
Sbjct: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV-GAASAPAKESPRKGAAP 388
Query: 220 -PAGGTGQ-----RRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTT 273
P G TG + G R S D EEE A Q +P+G Q R A+AP +
Sbjct: 389 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQAKPSGKAPQVR-AASAPAKES 446
Query: 274 GGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEE 305
R+G A AP P TG + +EE
Sbjct: 447 ----PRKGAAPAP-PRKTGPAAAQVQVGKQEE 473
Score = 49.3 bits (116), Expect = 4e-06
Identities = 53/267 (19%), Positives = 97/267 (36%), Gaps = 15/267 (5%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
+P+++ + G + + S + + + AA+APA + G + P P
Sbjct: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG---KGATPAPPG 321
Query: 94 RRPAGGTGQRRGS-RSSSSADQQGAQDREEEAAAAPA---PTSSGHRTEKRKPQQPQCR- 148
+ A + + G S + + + D EEE AA A +SG ++ P
Sbjct: 322 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 381
Query: 149 PAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 208
P G P+ + +A REE++ SS ++ + Q +P+G Q
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQ------SSSEESDSEEEAPAQAKPSGKAPQ 435
Query: 209 RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAA 268
R + + P G ++ P+A Q + +EE++ AA
Sbjct: 436 VRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAA 495
Query: 269 PVPTTGGTGQ-RRGTAAAPAPTSTGTG 294
V G + Q + + P G G
Sbjct: 496 QVKPLGKSPQVKPASTMGMGPLGKGAG 522
Score = 45.4 bits (106), Expect = 6e-05
Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 42/280 (15%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAG-GTGQ 102
AGGT QR SS S + +++ A S G + + P + G GT
Sbjct: 683 AGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 103 RRGSRSSSSADQQGAQDRE-----------EEAAAAPAPTSSGHRTEKRKPQQPQCRPAA 151
++ + Q A+ +E EEAAA+PA + + + K R +
Sbjct: 742 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 152 GTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
G G +A Q A+ R PV P T RG
Sbjct: 802 AKGTISAPGKVVTAAAQ-AKQRSPSKVKPPVR-----------------NPQNSTVLARG 843
Query: 212 SRSSPSRQPAGGT-GQRRGSRSSPSADQQRAQDREEEA-AQPQRRPAGGTGQRRGTAAAP 269
S PS A T Q + S + D EEEA Q +P+G T Q R A AP
Sbjct: 844 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR-AALAP 902
Query: 270 VPTTGGTGQRRGTAAAP----APTSTGTGQRRGSEEMEEE 305
+ R+G A P P++ G++ S EE
Sbjct: 903 AKES----PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 938
Score = 43.5 bits (101), Expect = 2e-04
Identities = 63/308 (20%), Positives = 102/308 (33%), Gaps = 52/308 (16%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPT-SRGHRTEKRKPQ 90
P+ P + P+ G+ S S + + D E A APA S G+ + +
Sbjct: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 91 QPQRRPAGGTG--------QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKP 142
P + P G ++ S SS + + D EE AA T++ + + P
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM---TAAQAKPALKIP 639
Query: 143 QQPQCRPAAGTG---------------QRRGSGCSPS----------------ADQQRAQ 171
Q C T ++ G+ SP+ +
Sbjct: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 699
Query: 172 DREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSR 231
D EEE T V K +++ P G+ + + P + T Q + +
Sbjct: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT-QVKAEK 758
Query: 232 SSPSADQQRAQDREEEAAQPQ--RRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
S + D EE AA P + T + AAA P+ +GT +AP
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA------KGTISAPGKV 812
Query: 290 STGTGQRR 297
T Q +
Sbjct: 813 VTAAAQAK 820
Score = 42.4 bits (98), Expect = 5e-04
Identities = 56/292 (19%), Positives = 97/292 (33%), Gaps = 20/292 (6%)
Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 88
+TK +P++ + + + ++ + Q A + + AA AP R +
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR-KGAA 387
Query: 89 PQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRK-PQQPQC 147
P P + + G R S D EEEA A P+ + P +
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Query: 148 RPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
R A R +G P+A Q + +EE++ ++ S R Q +P G +
Sbjct: 448 RKGAAPAPPRKTG--PAAAQVQVGKQEEDSRSSS-EESDSDREALAAMNAAQVKPLGKSP 504
Query: 208 QRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAA 267
Q + + + G G + P+ + EE++ + + TA
Sbjct: 505 QVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 564
Query: 268 APV------------PTTG---GTGQRRGTAAAPAPTSTGTGQRRGSEEMEE 304
AP PT+ G Q+ G A SEE +
Sbjct: 565 APAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Score = 41.2 bits (95), Expect = 0.001
Identities = 58/246 (23%), Positives = 85/246 (34%), Gaps = 27/246 (10%)
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
Q+ ++ EEE+ + A S K Q + PA +R+ S+ A +
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA-------ARAPSAKGTISAPGK 811
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS-----ADQQRAQDREE 175
AAA S K + P P T RG PS A +AQ E
Sbjct: 812 VVTAAAQAKQRSPS------KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 865
Query: 176 EATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPS 235
E + + S +E+ Q +P+G T Q R + + P G ++ PS
Sbjct: 866 EDSGSSEEESD---SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPS 922
Query: 236 ADQQRAQD----REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTST 291
A Q QD EE+ PA T + P+ G AA PA
Sbjct: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ--VIKPPLIFVDPNRSPAGPAATPAQAQA 980
Query: 292 GTGQRR 297
+ R+
Sbjct: 981 ASTPRK 986
Score = 33.9 bits (76), Expect = 0.19
Identities = 48/226 (21%), Positives = 79/226 (34%), Gaps = 34/226 (15%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEA-----AAAPAPTS-RGHRTEK-R 87
P+ P+ AG + + S S Q+G + + A A +P TS + T K R
Sbjct: 1029 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 88 KP-----QQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAA---AAPAPTSSGHRTEK 139
KP QQ + P S SSS +++ G + ++A P P+ + E+
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE 1148
Query: 140 RKPQQPQ--------------CRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTS 185
+ + P + S +P D + +T A
Sbjct: 1149 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPS----VSSTLAAKDDP 1204
Query: 186 SGHRTEKRKRLQLQCQP-AGGTGQRRGSRSSPSRQPAGGTGQRRGS 230
G + K ++ P GG G+ SR+P G G + S
Sbjct: 1205 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQAS 1250
Score = 32.3 bits (72), Expect = 0.54
Identities = 27/128 (21%), Positives = 57/128 (44%), Gaps = 14/128 (10%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1322 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1374
Query: 63 GAQDREEEAAAAPAPTSRG-------HRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQ 115
GA+D EE T G + EK+K + ++ +++ ++S+ +
Sbjct: 1375 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1434
Query: 116 GAQDREEE 123
+Q ++++
Sbjct: 1435 PSQKKKKK 1442
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 56.6 bits (135), Expect = 3e-08
Identities = 82/332 (24%), Positives = 128/332 (38%), Gaps = 55/332 (16%)
Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72
RK E S + + + P +P + + S S ++ D E + +
Sbjct: 158 RKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS 217
Query: 73 AAPAPTSRGHRTEKRKPQQPQRRPAGG-----TGQRRGS-----------RSSSSADQQG 116
PA + K P + + PA G T Q +G S + ++G
Sbjct: 218 VKPAQVKASSVSTKESPAR-KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG 276
Query: 117 AQDREEEAAAAPAPTSSGHR-TEKRKPQQPQCRPAAGTGQRRGSGCSPS--------ADQ 167
++ EE APA T S + +EK + PA GT G G +P+ A Q
Sbjct: 277 SESEEE----APAGTRSQVKASEKILQVRAASAPAKGTP---GKGATPAPPGKAGAVASQ 329
Query: 168 QRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQ-------- 219
+A EE++ ++ +S + LQ + +G T Q G+ S+P+++
Sbjct: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV-GAASAPAKESPRKGAAP 388
Query: 220 -PAGGTGQ-----RRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTT 273
P G TG + G R S D EEE A Q +P+G Q R A+AP +
Sbjct: 389 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQAKPSGKAPQVR-AASAPAKES 446
Query: 274 GGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEE 305
R+G A AP P TG + +EE
Sbjct: 447 ----PRKGAAPAP-PRKTGPAAAQVQVGKQEE 473
Score = 49.3 bits (116), Expect = 4e-06
Identities = 53/267 (19%), Positives = 97/267 (36%), Gaps = 15/267 (5%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
+P+++ + G + + S + + + AA+APA + G + P P
Sbjct: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG---KGATPAPPG 321
Query: 94 RRPAGGTGQRRGS-RSSSSADQQGAQDREEEAAAAPA---PTSSGHRTEKRKPQQPQCR- 148
+ A + + G S + + + D EEE AA A +SG ++ P
Sbjct: 322 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 381
Query: 149 PAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 208
P G P+ + +A REE++ SS ++ + Q +P+G Q
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQ------SSSEESDSEEEAPAQAKPSGKAPQ 435
Query: 209 RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAA 268
R + + P G ++ P+A Q + +EE++ AA
Sbjct: 436 VRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAA 495
Query: 269 PVPTTGGTGQ-RRGTAAAPAPTSTGTG 294
V G + Q + + P G G
Sbjct: 496 QVKPLGKSPQVKPASTMGMGPLGKGAG 522
Score = 45.4 bits (106), Expect = 6e-05
Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 42/280 (15%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAG-GTGQ 102
AGGT QR SS S + +++ A S G + + P + G GT
Sbjct: 683 AGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 103 RRGSRSSSSADQQGAQDRE-----------EEAAAAPAPTSSGHRTEKRKPQQPQCRPAA 151
++ + Q A+ +E EEAAA+PA + + + K R +
Sbjct: 742 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 152 GTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
G G +A Q A+ R PV P T RG
Sbjct: 802 AKGTISAPGKVVTAAAQ-AKQRSPSKVKPPVR-----------------NPQNSTVLARG 843
Query: 212 SRSSPSRQPAGGT-GQRRGSRSSPSADQQRAQDREEEA-AQPQRRPAGGTGQRRGTAAAP 269
S PS A T Q + S + D EEEA Q +P+G T Q R A AP
Sbjct: 844 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR-AALAP 902
Query: 270 VPTTGGTGQRRGTAAAP----APTSTGTGQRRGSEEMEEE 305
+ R+G A P P++ G++ S EE
Sbjct: 903 AKES----PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 938
Score = 43.5 bits (101), Expect = 2e-04
Identities = 63/308 (20%), Positives = 102/308 (33%), Gaps = 52/308 (16%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPT-SRGHRTEKRKPQ 90
P+ P + P+ G+ S S + + D E A APA S G+ + +
Sbjct: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 91 QPQRRPAGGTG--------QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKP 142
P + P G ++ S SS + + D EE AA T++ + + P
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM---TAAQAKPALKIP 639
Query: 143 QQPQCRPAAGTG---------------QRRGSGCSPS----------------ADQQRAQ 171
Q C T ++ G+ SP+ +
Sbjct: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 699
Query: 172 DREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSR 231
D EEE T V K +++ P G+ + + P + T Q + +
Sbjct: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT-QVKAEK 758
Query: 232 SSPSADQQRAQDREEEAAQPQ--RRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
S + D EE AA P + T + AAA P+ +GT +AP
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA------KGTISAPGKV 812
Query: 290 STGTGQRR 297
T Q +
Sbjct: 813 VTAAAQAK 820
Score = 42.4 bits (98), Expect = 5e-04
Identities = 56/292 (19%), Positives = 97/292 (33%), Gaps = 20/292 (6%)
Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 88
+TK +P++ + + + ++ + Q A + + AA AP R +
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR-KGAA 387
Query: 89 PQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRK-PQQPQC 147
P P + + G R S D EEEA A P+ + P +
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Query: 148 RPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
R A R +G P+A Q + +EE++ ++ S R Q +P G +
Sbjct: 448 RKGAAPAPPRKTG--PAAAQVQVGKQEEDSRSSS-EESDSDREALAAMNAAQVKPLGKSP 504
Query: 208 QRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAA 267
Q + + + G G + P+ + EE++ + + TA
Sbjct: 505 QVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 564
Query: 268 APV------------PTTG---GTGQRRGTAAAPAPTSTGTGQRRGSEEMEE 304
AP PT+ G Q+ G A SEE +
Sbjct: 565 APAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Score = 41.2 bits (95), Expect = 0.001
Identities = 58/246 (23%), Positives = 85/246 (34%), Gaps = 27/246 (10%)
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
Q+ ++ EEE+ + A S K Q + PA +R+ S+ A +
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA-------ARAPSAKGTISAPGK 811
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS-----ADQQRAQDREE 175
AAA S K + P P T RG PS A +AQ E
Sbjct: 812 VVTAAAQAKQRSPS------KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 865
Query: 176 EATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPS 235
E + + S +E+ Q +P+G T Q R + + P G ++ PS
Sbjct: 866 EDSGSSEEESD---SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPS 922
Query: 236 ADQQRAQD----REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTST 291
A Q QD EE+ PA T + P+ G AA PA
Sbjct: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ--VIKPPLIFVDPNRSPAGPAATPAQAQA 980
Query: 292 GTGQRR 297
+ R+
Sbjct: 981 ASTPRK 986
Score = 34.3 bits (77), Expect = 0.14
Identities = 57/276 (20%), Positives = 110/276 (39%), Gaps = 36/276 (13%)
Query: 17 ESSEGD------QWLENEKTKPLRP--QQQPQCQPAGGTGQRRGSGSSPSADQQGAQD-R 67
ESSE D L T L P Q + P + S + D G Q+ +
Sbjct: 1189 ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1248
Query: 68 EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSAD------QQGAQDRE 121
++AA +P + G Q R+P G G + S + ++ Q E
Sbjct: 1249 PQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNE 1308
Query: 122 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTG----QRRGSGCSPSADQQRAQDREE-- 175
+ A+ + ++RK + ++ G +R+ SG P+A R++ +++
Sbjct: 1309 AQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLG 1368
Query: 176 -----EATAAPVPTSSGHRTE-KRKRLQLQCQPAGGTGQ--RRGSRSSPSRQPAGGTGQ- 226
EA+ +P TS+ + + KR + + G G +G++ P + G G
Sbjct: 1369 AGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTV 1428
Query: 227 RRGSRSSPSADQQ------RAQDREEEAAQPQRRPA 256
G +S+P + ++ R +D+E++ + + + A
Sbjct: 1429 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKA 1464
Score = 32.3 bits (72), Expect = 0.54
Identities = 27/128 (21%), Positives = 57/128 (44%), Gaps = 14/128 (10%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1359 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1411
Query: 63 GAQDREEEAAAAPAPTSRG-------HRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQ 115
GA+D EE T G + EK+K + ++ +++ ++S+ +
Sbjct: 1412 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1471
Query: 116 GAQDREEE 123
+Q ++++
Sbjct: 1472 PSQKKKKK 1479
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 56.6 bits (135), Expect = 3e-08
Identities = 82/332 (24%), Positives = 128/332 (38%), Gaps = 55/332 (16%)
Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72
RK E S + + + P +P + + S S ++ D E + +
Sbjct: 158 RKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS 217
Query: 73 AAPAPTSRGHRTEKRKPQQPQRRPAGG-----TGQRRGS-----------RSSSSADQQG 116
PA + K P + + PA G T Q +G S + ++G
Sbjct: 218 VKPAQVKASSVSTKESPAR-KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG 276
Query: 117 AQDREEEAAAAPAPTSSGHR-TEKRKPQQPQCRPAAGTGQRRGSGCSPS--------ADQ 167
++ EE APA T S + +EK + PA GT G G +P+ A Q
Sbjct: 277 SESEEE----APAGTRSQVKASEKILQVRAASAPAKGTP---GKGATPAPPGKAGAVASQ 329
Query: 168 QRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQ-------- 219
+A EE++ ++ +S + LQ + +G T Q G+ S+P+++
Sbjct: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV-GAASAPAKESPRKGAAP 388
Query: 220 -PAGGTGQ-----RRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTT 273
P G TG + G R S D EEE A Q +P+G Q R A+AP +
Sbjct: 389 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQAKPSGKAPQVR-AASAPAKES 446
Query: 274 GGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEE 305
R+G A AP P TG + +EE
Sbjct: 447 ----PRKGAAPAP-PRKTGPAAAQVQVGKQEE 473
Score = 49.3 bits (116), Expect = 4e-06
Identities = 53/267 (19%), Positives = 97/267 (36%), Gaps = 15/267 (5%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
+P+++ + G + + S + + + AA+APA + G + P P
Sbjct: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG---KGATPAPPG 321
Query: 94 RRPAGGTGQRRGS-RSSSSADQQGAQDREEEAAAAPA---PTSSGHRTEKRKPQQPQCR- 148
+ A + + G S + + + D EEE AA A +SG ++ P
Sbjct: 322 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 381
Query: 149 PAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 208
P G P+ + +A REE++ SS ++ + Q +P+G Q
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQ------SSSEESDSEEEAPAQAKPSGKAPQ 435
Query: 209 RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAA 268
R + + P G ++ P+A Q + +EE++ AA
Sbjct: 436 VRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAA 495
Query: 269 PVPTTGGTGQ-RRGTAAAPAPTSTGTG 294
V G + Q + + P G G
Sbjct: 496 QVKPLGKSPQVKPASTMGMGPLGKGAG 522
Score = 45.4 bits (106), Expect = 6e-05
Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 42/280 (15%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAG-GTGQ 102
AGGT QR SS S + +++ A S G + + P + G GT
Sbjct: 683 AGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 103 RRGSRSSSSADQQGAQDRE-----------EEAAAAPAPTSSGHRTEKRKPQQPQCRPAA 151
++ + Q A+ +E EEAAA+PA + + + K R +
Sbjct: 742 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 152 GTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
G G +A Q A+ R PV P T RG
Sbjct: 802 AKGTISAPGKVVTAAAQ-AKQRSPSKVKPPVR-----------------NPQNSTVLARG 843
Query: 212 SRSSPSRQPAGGT-GQRRGSRSSPSADQQRAQDREEEA-AQPQRRPAGGTGQRRGTAAAP 269
S PS A T Q + S + D EEEA Q +P+G T Q R A AP
Sbjct: 844 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR-AALAP 902
Query: 270 VPTTGGTGQRRGTAAAP----APTSTGTGQRRGSEEMEEE 305
+ R+G A P P++ G++ S EE
Sbjct: 903 AKES----PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 938
Score = 43.5 bits (101), Expect = 2e-04
Identities = 63/308 (20%), Positives = 102/308 (33%), Gaps = 52/308 (16%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPT-SRGHRTEKRKPQ 90
P+ P + P+ G+ S S + + D E A APA S G+ + +
Sbjct: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 91 QPQRRPAGGTG--------QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKP 142
P + P G ++ S SS + + D EE AA T++ + + P
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM---TAAQAKPALKIP 639
Query: 143 QQPQCRPAAGTG---------------QRRGSGCSPS----------------ADQQRAQ 171
Q C T ++ G+ SP+ +
Sbjct: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 699
Query: 172 DREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSR 231
D EEE T V K +++ P G+ + + P + T Q + +
Sbjct: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT-QVKAEK 758
Query: 232 SSPSADQQRAQDREEEAAQPQ--RRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
S + D EE AA P + T + AAA P+ +GT +AP
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA------KGTISAPGKV 812
Query: 290 STGTGQRR 297
T Q +
Sbjct: 813 VTAAAQAK 820
Score = 42.4 bits (98), Expect = 5e-04
Identities = 56/292 (19%), Positives = 97/292 (33%), Gaps = 20/292 (6%)
Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 88
+TK +P++ + + + ++ + Q A + + AA AP R +
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR-KGAA 387
Query: 89 PQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRK-PQQPQC 147
P P + + G R S D EEEA A P+ + P +
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Query: 148 RPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
R A R +G P+A Q + +EE++ ++ S R Q +P G +
Sbjct: 448 RKGAAPAPPRKTG--PAAAQVQVGKQEEDSRSSS-EESDSDREALAAMNAAQVKPLGKSP 504
Query: 208 QRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAA 267
Q + + + G G + P+ + EE++ + + TA
Sbjct: 505 QVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 564
Query: 268 APV------------PTTG---GTGQRRGTAAAPAPTSTGTGQRRGSEEMEE 304
AP PT+ G Q+ G A SEE +
Sbjct: 565 APAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Score = 41.2 bits (95), Expect = 0.001
Identities = 58/246 (23%), Positives = 85/246 (34%), Gaps = 27/246 (10%)
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
Q+ ++ EEE+ + A S K Q + PA +R+ S+ A +
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA-------ARAPSAKGTISAPGK 811
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS-----ADQQRAQDREE 175
AAA S K + P P T RG PS A +AQ E
Sbjct: 812 VVTAAAQAKQRSPS------KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 865
Query: 176 EATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPS 235
E + + S +E+ Q +P+G T Q R + + P G ++ PS
Sbjct: 866 EDSGSSEEESD---SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPS 922
Query: 236 ADQQRAQD----REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTST 291
A Q QD EE+ PA T + P+ G AA PA
Sbjct: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ--VIKPPLIFVDPNRSPAGPAATPAQAQA 980
Query: 292 GTGQRR 297
+ R+
Sbjct: 981 ASTPRK 986
Score = 35.0 bits (79), Expect = 0.083
Identities = 49/221 (22%), Positives = 76/221 (34%), Gaps = 25/221 (11%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEA-----AAAPAPTS-RGHRTEK-R 87
P+ P+ AG + + S S Q+G + + A A +P TS + T K R
Sbjct: 1029 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 88 KP-----QQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRT----- 137
KP QQ + P S SSS +++ G + ++A PT S T
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEET 1148
Query: 138 -------EKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRT 190
+ P Q G + + A + +T A G +
Sbjct: 1149 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1208
Query: 191 EKRKRLQLQCQP-AGGTGQRRGSRSSPSRQPAGGTGQRRGS 230
K ++ P GG G+ SR+P G G + S
Sbjct: 1209 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQAS 1249
Score = 32.3 bits (72), Expect = 0.54
Identities = 27/128 (21%), Positives = 57/128 (44%), Gaps = 14/128 (10%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1321 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1373
Query: 63 GAQDREEEAAAAPAPTSRG-------HRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQ 115
GA+D EE T G + EK+K + ++ +++ ++S+ +
Sbjct: 1374 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1433
Query: 116 GAQDREEE 123
+Q ++++
Sbjct: 1434 PSQKKKKK 1441
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 56.6 bits (135), Expect = 3e-08
Identities = 82/332 (24%), Positives = 128/332 (38%), Gaps = 55/332 (16%)
Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72
RK E S + + + P +P + + S S ++ D E + +
Sbjct: 158 RKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS 217
Query: 73 AAPAPTSRGHRTEKRKPQQPQRRPAGG-----TGQRRGS-----------RSSSSADQQG 116
PA + K P + + PA G T Q +G S + ++G
Sbjct: 218 VKPAQVKASSVSTKESPAR-KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG 276
Query: 117 AQDREEEAAAAPAPTSSGHR-TEKRKPQQPQCRPAAGTGQRRGSGCSPS--------ADQ 167
++ EE APA T S + +EK + PA GT G G +P+ A Q
Sbjct: 277 SESEEE----APAGTRSQVKASEKILQVRAASAPAKGTP---GKGATPAPPGKAGAVASQ 329
Query: 168 QRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQ-------- 219
+A EE++ ++ +S + LQ + +G T Q G+ S+P+++
Sbjct: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV-GAASAPAKESPRKGAAP 388
Query: 220 -PAGGTGQ-----RRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTT 273
P G TG + G R S D EEE A Q +P+G Q R A+AP +
Sbjct: 389 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQAKPSGKAPQVR-AASAPAKES 446
Query: 274 GGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEE 305
R+G A AP P TG + +EE
Sbjct: 447 ----PRKGAAPAP-PRKTGPAAAQVQVGKQEE 473
Score = 49.3 bits (116), Expect = 4e-06
Identities = 53/267 (19%), Positives = 97/267 (36%), Gaps = 15/267 (5%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
+P+++ + G + + S + + + AA+APA + G + P P
Sbjct: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG---KGATPAPPG 321
Query: 94 RRPAGGTGQRRGS-RSSSSADQQGAQDREEEAAAAPA---PTSSGHRTEKRKPQQPQCR- 148
+ A + + G S + + + D EEE AA A +SG ++ P
Sbjct: 322 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 381
Query: 149 PAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 208
P G P+ + +A REE++ SS ++ + Q +P+G Q
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQ------SSSEESDSEEEAPAQAKPSGKAPQ 435
Query: 209 RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAA 268
R + + P G ++ P+A Q + +EE++ AA
Sbjct: 436 VRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAA 495
Query: 269 PVPTTGGTGQ-RRGTAAAPAPTSTGTG 294
V G + Q + + P G G
Sbjct: 496 QVKPLGKSPQVKPASTMGMGPLGKGAG 522
Score = 45.4 bits (106), Expect = 6e-05
Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 42/280 (15%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAG-GTGQ 102
AGGT QR SS S + +++ A S G + + P + G GT
Sbjct: 683 AGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 103 RRGSRSSSSADQQGAQDRE-----------EEAAAAPAPTSSGHRTEKRKPQQPQCRPAA 151
++ + Q A+ +E EEAAA+PA + + + K R +
Sbjct: 742 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 152 GTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
G G +A Q A+ R PV P T RG
Sbjct: 802 AKGTISAPGKVVTAAAQ-AKQRSPSKVKPPVR-----------------NPQNSTVLARG 843
Query: 212 SRSSPSRQPAGGT-GQRRGSRSSPSADQQRAQDREEEA-AQPQRRPAGGTGQRRGTAAAP 269
S PS A T Q + S + D EEEA Q +P+G T Q R A AP
Sbjct: 844 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR-AALAP 902
Query: 270 VPTTGGTGQRRGTAAAP----APTSTGTGQRRGSEEMEEE 305
+ R+G A P P++ G++ S EE
Sbjct: 903 AKES----PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 938
Score = 43.5 bits (101), Expect = 2e-04
Identities = 63/308 (20%), Positives = 102/308 (33%), Gaps = 52/308 (16%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPT-SRGHRTEKRKPQ 90
P+ P + P+ G+ S S + + D E A APA S G+ + +
Sbjct: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 91 QPQRRPAGGTG--------QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKP 142
P + P G ++ S SS + + D EE AA T++ + + P
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM---TAAQAKPALKIP 639
Query: 143 QQPQCRPAAGTG---------------QRRGSGCSPS----------------ADQQRAQ 171
Q C T ++ G+ SP+ +
Sbjct: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 699
Query: 172 DREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSR 231
D EEE T V K +++ P G+ + + P + T Q + +
Sbjct: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT-QVKAEK 758
Query: 232 SSPSADQQRAQDREEEAAQPQ--RRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
S + D EE AA P + T + AAA P+ +GT +AP
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA------KGTISAPGKV 812
Query: 290 STGTGQRR 297
T Q +
Sbjct: 813 VTAAAQAK 820
Score = 42.4 bits (98), Expect = 5e-04
Identities = 56/292 (19%), Positives = 97/292 (33%), Gaps = 20/292 (6%)
Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 88
+TK +P++ + + + ++ + Q A + + AA AP R +
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR-KGAA 387
Query: 89 PQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRK-PQQPQC 147
P P + + G R S D EEEA A P+ + P +
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Query: 148 RPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
R A R +G P+A Q + +EE++ ++ S R Q +P G +
Sbjct: 448 RKGAAPAPPRKTG--PAAAQVQVGKQEEDSRSSS-EESDSDREALAAMNAAQVKPLGKSP 504
Query: 208 QRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAA 267
Q + + + G G + P+ + EE++ + + TA
Sbjct: 505 QVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 564
Query: 268 APV------------PTTG---GTGQRRGTAAAPAPTSTGTGQRRGSEEMEE 304
AP PT+ G Q+ G A SEE +
Sbjct: 565 APAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Score = 38.5 bits (88), Expect = 0.008
Identities = 51/208 (24%), Positives = 74/208 (35%), Gaps = 25/208 (12%)
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
Q+ ++ EEE+ + A S K Q + PA +R+ S+ A +
Sbjct: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA-------ARAPSAKGTISAPGK 811
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS-----ADQQRAQDREE 175
AAA S K + P P T RG PS A +AQ E
Sbjct: 812 VVTAAAQAKQRSPS------KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 865
Query: 176 EATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPS 235
E + + S +E+ Q +P+G T Q R + + P G ++ PS
Sbjct: 866 EDSGSSEEESD---SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPS 922
Query: 236 ADQQRAQD----REEEAAQPQRRPAGGT 259
A Q QD EE+ PA T
Sbjct: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVT 950
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 56.2 bits (134), Expect = 3e-08
Identities = 70/275 (25%), Positives = 98/275 (35%), Gaps = 38/275 (13%)
Query: 36 QQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 95
Q P+ QP G G++R +G SA Q + A A SRG + + P R
Sbjct: 1412 QGPPRDQPGGPAGRQRPTGRPTSARQAMGHRHKAGGAGRSAEQSRGAGKNRAGLELPLGR 1471
Query: 96 PAGGTGQRRGSRSSSSADQ-------------------QGAQDREEEAAAAPAPTSSGHR 136
P + GS+ + G EE AAAP PT HR
Sbjct: 1472 PPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAAAPTPT---HR 1528
Query: 137 TEKRKP-----QQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTE 191
P ++PQ R A + P A Q + +E + +S+ +E
Sbjct: 1529 RTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSSSASSLSE 1588
Query: 192 KRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQP 251
P RG + ++ P G G R S SP A ++ Q R +A P
Sbjct: 1589 PEPSEPPAVHP-------RGREPAVTKDPGPGGG--RDSSPSPRAAEELLQ-RCISSALP 1638
Query: 252 QRRPAGGTGQRRGTAAAPVPTTGGTGQR-RGTAAA 285
+RRP +RR A + G R RG AA
Sbjct: 1639 RRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAA 1673
Score = 38.1 bits (87), Expect = 0.010
Identities = 59/279 (21%), Positives = 96/279 (34%), Gaps = 26/279 (9%)
Query: 36 QQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 95
+++PQ + + + P A Q + +E +S +E + P
Sbjct: 1539 RERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSSSASSLSEPEPSEPPAVH 1598
Query: 96 PAG---------GTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQ 146
P G G G R S S A ++ Q A P SG R K + +
Sbjct: 1599 PRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLD 1658
Query: 147 CRPAAGTGQR--RGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAG 204
RPA G+ +R +G ++D + R + A + T + +
Sbjct: 1659 ERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESDSIL 1718
Query: 205 G--TGQRRGSRSSP-----SRQPAGGTG-----QRRGSRSSPSADQQRAQDREEEAAQPQ 252
+G GS P RQ G G ++RG+ S ++ R+ E+ Q
Sbjct: 1719 SFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQ 1778
Query: 253 RRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTST 291
+ G RG VP+ Q +GT P P +T
Sbjct: 1779 KTTPGVPAVLRGRTVIYVPSPAPRAQPKGT---PGPRAT 1814
Score = 37.0 bits (84), Expect = 0.022
Identities = 64/301 (21%), Positives = 103/301 (34%), Gaps = 32/301 (10%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR RL K SS + ++PL P+++P A G G+ P +
Sbjct: 1859 PRSATPPARLAKTPSSSSSQT---SPASQPL-PRKRPPVTQAAGALPGPGASPVPKTPAR 1914
Query: 63 GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR-PAGGTGQRRGSRSSSSADQQGAQDRE 121
++ + +P R +R P R P G R G+ + A + G
Sbjct: 1915 TLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGA-RGGRLGLV 1973
Query: 122 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRG--SGCSPSADQQRAQDREEEATA 179
A+A + + S R+ R+ Q + + G +RR S +A + A
Sbjct: 1974 RVASALSSGSESSDRSGFRR-QLTFIKESPGLRRRRSELSSAESAASAPQGASPRRGRPA 2032
Query: 180 APVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQ 239
P R E+ R++P + PA + +R SP
Sbjct: 2033 LPAVFLCSSRCEEL-------------------RAAPRQGPAPARQRPPAARPSPGERPA 2073
Query: 240 RAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGS 299
R E + P R PA + A+ P + RR A PA ++ RR S
Sbjct: 2074 RRTTSESPSRLPVRAPAARPETVKRYASLPHISVA----RRPDGAVPAAPASADAARRSS 2129
Query: 300 E 300
+
Sbjct: 2130 D 2130
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 55.1 bits (131), Expect = 8e-08
Identities = 61/293 (20%), Positives = 110/293 (37%), Gaps = 20/293 (6%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76
E S D E++K +P++ +PQ + A ++ S S D + + E P
Sbjct: 130 EESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDS---DSDSSSEDEPPKNQKPK 186
Query: 77 PTSRGHRTEKRKPQQPQRR-PAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGH 135
T + + + P +P R P G+ S SSSS+ EE+AAA P T
Sbjct: 187 ITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKK 246
Query: 136 RTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREE------EATAAPVPTSSGHR 189
+ + P + P + S +Q++ + +AP P S
Sbjct: 247 QVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGT 306
Query: 190 TEKRKRLQLQCQPAGGTGQRRGSRSSPSRQ----PAGGTGQRRGSRSSPS--ADQQRAQD 243
+K ++ Q QP + S S + P + ++ P+ A + +
Sbjct: 307 QPPKKAVEKQ-QPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDS 365
Query: 244 REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQR 296
+ ++++ P+ G + ++ P TT + AAAP G GQ+
Sbjct: 366 SDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVK--PAAAP-KQPVGGGQK 415
Score = 50.8 bits (120), Expect = 1e-06
Identities = 66/301 (21%), Positives = 117/301 (38%), Gaps = 46/301 (15%)
Query: 18 SSEGDQWLENEK---TKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAA 74
S E D E EK TK + + + PA ++ SS S+D ++D +EA +
Sbjct: 326 SDESDSSSEEEKKPPTKAVVSKATTKPPPA----KKAAESSSDSSDSDSSED--DEAPSK 379
Query: 75 PAPTSRGHRTEKR--------KPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAA 126
PA T++ + KP ++P GG + ++ SS+ ++ + EEE
Sbjct: 380 PAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTK 439
Query: 127 APAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSS 186
T+ T K P + +GS S S + + EEE T+
Sbjct: 440 KMVATTKPKATAKAALSLPAKQAP------QGSRDSSSDSDSSSSEEEEEKTS------- 486
Query: 187 GHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDRE- 245
++ +K+ Q + AGG ++PS+ + G+ S SS S D ++ +
Sbjct: 487 --KSAVKKKPQ---KVAGG--------AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533
Query: 246 --EEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSEEME 303
+ + +PQ A GT + + + AA S +R+ +E +
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAK 593
Query: 304 E 304
E
Sbjct: 594 E 594
Score = 48.9 bits (115), Expect = 6e-06
Identities = 64/306 (20%), Positives = 111/306 (36%), Gaps = 51/306 (16%)
Query: 24 WLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR 83
WL++ K P+++ Q A G ++ + S+D + + + EEE PA
Sbjct: 57 WLKSAKV----PERKLQ---ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPA------- 102
Query: 84 TEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEE--------------AAAAPA 129
+K P +R G+ S SS+ ++ + D +EE A AA A
Sbjct: 103 ---KKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKA 159
Query: 130 P----------TSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATA 179
P + S E K Q+P+ P Q + A + A + +++
Sbjct: 160 PPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSS 219
Query: 180 APVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQ 239
+ +SS +E+ K P +++ +P + A T R+ S S S
Sbjct: 220 SSSSSSSSDDSEEEK---AAATPKKTVPKKQVVAKAPVK--AATTPTRKSSSSEDS---- 270
Query: 240 RAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGS 299
+ D EEE +P + G +A P + GT + P + S
Sbjct: 271 -SSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDES 329
Query: 300 EEMEEE 305
+ EE
Sbjct: 330 DSSSEE 335
Score = 33.1 bits (74), Expect = 0.32
Identities = 34/159 (21%), Positives = 65/159 (40%), Gaps = 26/159 (16%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76
+SS ++ E EKT +++PQ + AGG S P++ ++G + +++ +
Sbjct: 474 DSSSSEE--EEEKTSKSAVKKKPQ-KVAGGAAP-----SKPASAKKGKAESSNSSSSDDS 525
Query: 77 PTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGH- 135
+ + + +PQ A GT + + A + ++ EE+ AA + SG
Sbjct: 526 SEEEEEKLKGKGSPRPQAPKANGTSAL--TAQNGKAAKNSEEEEEEKKKAAVVVSKSGSL 583
Query: 136 ---------------RTEKRKPQQPQCRPAAGTGQRRGS 159
+ +K K Q P P G++R S
Sbjct: 584 KKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRAS 622
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 53.1 bits (126), Expect = 3e-07
Identities = 73/323 (22%), Positives = 125/323 (38%), Gaps = 41/323 (12%)
Query: 5 QKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGA 64
+ E +T R +S L + ++ + + + + AG TG ++
Sbjct: 93 EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLL 152
Query: 65 QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEA 124
+ +A P+ + T + ++ PA G + G S+ AD E+ +
Sbjct: 153 SGKSPRKSAEPSANT----TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSS----EDTS 204
Query: 125 AAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS--------ADQQRAQDREEE 176
+++ +EK + PA GT G G +P+ A Q +A EE+
Sbjct: 205 SSSDETDVEVKASEKILQVRAASAPAKGTP---GKGATPAPPGKAGAVASQTKAGKPEED 261
Query: 177 ATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQ---------PAGGTGQ- 226
+ ++ +S + LQ + +G T Q G+ S+P+++ P G TG
Sbjct: 262 SESSSEESSDSEEETPAAKALLQAKASGKTSQV-GAASAPAKESPRKGAAPAPPGKTGPA 320
Query: 227 ----RRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGT 282
+ G R S D EEE A Q +P+G Q R A+AP + R+G
Sbjct: 321 VAKAQAGKREEDSQSSSEESDSEEE-APAQAKPSGKAPQVR-AASAPAKES----PRKGA 374
Query: 283 AAAPAPTSTGTGQRRGSEEMEEE 305
A AP P TG + +EE
Sbjct: 375 APAP-PRKTGPAAAQVQVGKQEE 396
Score = 46.6 bits (109), Expect = 3e-05
Identities = 55/263 (20%), Positives = 95/263 (36%), Gaps = 21/263 (7%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEE------AAAAPAPTSRGHRTEKRKPQQPQRRPA 97
+ G +S S+D+ + + E AA+APA + G + P P + A
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPG---KGATPAPPGKAGA 248
Query: 98 GGTGQRRGS-RSSSSADQQGAQDREEEAAAAPA---PTSSGHRTEKRKPQQPQCR-PAAG 152
+ + G S + + + D EEE AA A +SG ++ P P G
Sbjct: 249 VASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG 308
Query: 153 TGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGS 212
P+ + +A REE++ SS ++ + Q +P+G Q R +
Sbjct: 309 AAPAPPGKTGPAVAKAQAGKREEDSQ------SSSEESDSEEEAPAQAKPSGKAPQVRAA 362
Query: 213 RSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPT 272
+ P G ++ P+A Q + +EE++ AA V
Sbjct: 363 SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKP 422
Query: 273 TGGTGQ-RRGTAAAPAPTSTGTG 294
G + Q + + P G G
Sbjct: 423 LGKSPQVKPASTMGMGPLGKGAG 445
Score = 45.4 bits (106), Expect = 6e-05
Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 42/280 (15%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAG-GTGQ 102
AGGT QR SS S + +++ A S G + + P + G GT
Sbjct: 606 AGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 664
Query: 103 RRGSRSSSSADQQGAQDRE-----------EEAAAAPAPTSSGHRTEKRKPQQPQCRPAA 151
++ + Q A+ +E EEAAA+PA + + + K R +
Sbjct: 665 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 724
Query: 152 GTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
G G +A Q A+ R PV P T RG
Sbjct: 725 AKGTISAPGKVVTAAAQ-AKQRSPSKVKPPVR-----------------NPQNSTVLARG 766
Query: 212 SRSSPSRQPAGGT-GQRRGSRSSPSADQQRAQDREEEA-AQPQRRPAGGTGQRRGTAAAP 269
S PS A T Q + S + D EEEA Q +P+G T Q R A AP
Sbjct: 767 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR-AALAP 825
Query: 270 VPTTGGTGQRRGTAAAP----APTSTGTGQRRGSEEMEEE 305
+ R+G A P P++ G++ S EE
Sbjct: 826 AKES----PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 861
Score = 43.5 bits (101), Expect = 2e-04
Identities = 63/308 (20%), Positives = 102/308 (33%), Gaps = 52/308 (16%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPT-SRGHRTEKRKPQ 90
P+ P + P+ G+ S S + + D E A APA S G+ + +
Sbjct: 446 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 505
Query: 91 QPQRRPAGGTG--------QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKP 142
P + P G ++ S SS + + D EE AA T++ + + P
Sbjct: 506 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM---TAAQAKPALKIP 562
Query: 143 QQPQCRPAAGTG---------------QRRGSGCSPS----------------ADQQRAQ 171
Q C T ++ G+ SP+ +
Sbjct: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 622
Query: 172 DREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSR 231
D EEE T V K +++ P G+ + + P + T Q + +
Sbjct: 623 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT-QVKAEK 681
Query: 232 SSPSADQQRAQDREEEAAQPQ--RRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
S + D EE AA P + T + AAA P+ +GT +AP
Sbjct: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA------KGTISAPGKV 735
Query: 290 STGTGQRR 297
T Q +
Sbjct: 736 VTAAAQAK 743
Score = 42.4 bits (98), Expect = 5e-04
Identities = 56/292 (19%), Positives = 97/292 (33%), Gaps = 20/292 (6%)
Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 88
+TK +P++ + + + ++ + Q A + + AA AP R +
Sbjct: 252 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR-KGAA 310
Query: 89 PQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRK-PQQPQC 147
P P + + G R S D EEEA A P+ + P +
Sbjct: 311 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
Query: 148 RPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
R A R +G P+A Q + +EE++ ++ S R Q +P G +
Sbjct: 371 RKGAAPAPPRKTG--PAAAQVQVGKQEEDSRSSS-EESDSDREALAAMNAAQVKPLGKSP 427
Query: 208 QRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAA 267
Q + + + G G + P+ + EE++ + + TA
Sbjct: 428 QVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 487
Query: 268 APV------------PTTG---GTGQRRGTAAAPAPTSTGTGQRRGSEEMEE 304
AP PT+ G Q+ G A SEE +
Sbjct: 488 APAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 539
Score = 41.2 bits (95), Expect = 0.001
Identities = 58/246 (23%), Positives = 85/246 (34%), Gaps = 27/246 (10%)
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
Q+ ++ EEE+ + A S K Q + PA +R+ S+ A +
Sbjct: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA-------ARAPSAKGTISAPGK 734
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS-----ADQQRAQDREE 175
AAA S K + P P T RG PS A +AQ E
Sbjct: 735 VVTAAAQAKQRSPS------KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
Query: 176 EATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPS 235
E + + S +E+ Q +P+G T Q R + + P G ++ PS
Sbjct: 789 EDSGSSEEESD---SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPS 845
Query: 236 ADQQRAQD----REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTST 291
A Q QD EE+ PA T + P+ G AA PA
Sbjct: 846 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ--VIKPPLIFVDPNRSPAGPAATPAQAQA 903
Query: 292 GTGQRR 297
+ R+
Sbjct: 904 ASTPRK 909
Score = 34.3 bits (77), Expect = 0.14
Identities = 57/276 (20%), Positives = 110/276 (39%), Gaps = 36/276 (13%)
Query: 17 ESSEGD------QWLENEKTKPLRP--QQQPQCQPAGGTGQRRGSGSSPSADQQGAQD-R 67
ESSE D L T L P Q + P + S + D G Q+ +
Sbjct: 1113 ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1172
Query: 68 EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSAD------QQGAQDRE 121
++AA +P + G Q R+P G G + S + ++ Q E
Sbjct: 1173 PQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNE 1232
Query: 122 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTG----QRRGSGCSPSADQQRAQDREE-- 175
+ A+ + ++RK + ++ G +R+ SG P+A R++ +++
Sbjct: 1233 AQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLG 1292
Query: 176 -----EATAAPVPTSSGHRTE-KRKRLQLQCQPAGGTGQ--RRGSRSSPSRQPAGGTGQ- 226
EA+ +P TS+ + + KR + + G G +G++ P + G G
Sbjct: 1293 AGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTV 1352
Query: 227 RRGSRSSPSADQQ------RAQDREEEAAQPQRRPA 256
G +S+P + ++ R +D+E++ + + + A
Sbjct: 1353 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKA 1388
Score = 32.3 bits (72), Expect = 0.54
Identities = 27/128 (21%), Positives = 57/128 (44%), Gaps = 14/128 (10%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1283 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1335
Query: 63 GAQDREEEAAAAPAPTSRG-------HRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQ 115
GA+D EE T G + EK+K + ++ +++ ++S+ +
Sbjct: 1336 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1395
Query: 116 GAQDREEE 123
+Q ++++
Sbjct: 1396 PSQKKKKK 1403
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 53.1 bits (126), Expect = 3e-07
Identities = 73/323 (22%), Positives = 125/323 (38%), Gaps = 41/323 (12%)
Query: 5 QKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGA 64
+ E +T R +S L + ++ + + + + AG TG ++
Sbjct: 93 EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLL 152
Query: 65 QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEA 124
+ +A P+ + T + ++ PA G + G S+ AD E+ +
Sbjct: 153 SGKSPRKSAEPSANT----TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSS----EDTS 204
Query: 125 AAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS--------ADQQRAQDREEE 176
+++ +EK + PA GT G G +P+ A Q +A EE+
Sbjct: 205 SSSDETDVEVKASEKILQVRAASAPAKGTP---GKGATPAPPGKAGAVASQTKAGKPEED 261
Query: 177 ATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQ---------PAGGTGQ- 226
+ ++ +S + LQ + +G T Q G+ S+P+++ P G TG
Sbjct: 262 SESSSEESSDSEEETPAAKALLQAKASGKTSQV-GAASAPAKESPRKGAAPAPPGKTGPA 320
Query: 227 ----RRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGT 282
+ G R S D EEE A Q +P+G Q R A+AP + R+G
Sbjct: 321 VAKAQAGKREEDSQSSSEESDSEEE-APAQAKPSGKAPQVR-AASAPAKES----PRKGA 374
Query: 283 AAAPAPTSTGTGQRRGSEEMEEE 305
A AP P TG + +EE
Sbjct: 375 APAP-PRKTGPAAAQVQVGKQEE 396
Score = 46.6 bits (109), Expect = 3e-05
Identities = 55/263 (20%), Positives = 95/263 (36%), Gaps = 21/263 (7%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEE------AAAAPAPTSRGHRTEKRKPQQPQRRPA 97
+ G +S S+D+ + + E AA+APA + G + P P + A
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPG---KGATPAPPGKAGA 248
Query: 98 GGTGQRRGS-RSSSSADQQGAQDREEEAAAAPA---PTSSGHRTEKRKPQQPQCR-PAAG 152
+ + G S + + + D EEE AA A +SG ++ P P G
Sbjct: 249 VASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG 308
Query: 153 TGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGS 212
P+ + +A REE++ SS ++ + Q +P+G Q R +
Sbjct: 309 AAPAPPGKTGPAVAKAQAGKREEDSQ------SSSEESDSEEEAPAQAKPSGKAPQVRAA 362
Query: 213 RSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPT 272
+ P G ++ P+A Q + +EE++ AA V
Sbjct: 363 SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKP 422
Query: 273 TGGTGQ-RRGTAAAPAPTSTGTG 294
G + Q + + P G G
Sbjct: 423 LGKSPQVKPASTMGMGPLGKGAG 445
Score = 45.4 bits (106), Expect = 6e-05
Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 42/280 (15%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAG-GTGQ 102
AGGT QR SS S + +++ A S G + + P + G GT
Sbjct: 606 AGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 664
Query: 103 RRGSRSSSSADQQGAQDRE-----------EEAAAAPAPTSSGHRTEKRKPQQPQCRPAA 151
++ + Q A+ +E EEAAA+PA + + + K R +
Sbjct: 665 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 724
Query: 152 GTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
G G +A Q A+ R PV P T RG
Sbjct: 725 AKGTISAPGKVVTAAAQ-AKQRSPSKVKPPVR-----------------NPQNSTVLARG 766
Query: 212 SRSSPSRQPAGGT-GQRRGSRSSPSADQQRAQDREEEA-AQPQRRPAGGTGQRRGTAAAP 269
S PS A T Q + S + D EEEA Q +P+G T Q R A AP
Sbjct: 767 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR-AALAP 825
Query: 270 VPTTGGTGQRRGTAAAP----APTSTGTGQRRGSEEMEEE 305
+ R+G A P P++ G++ S EE
Sbjct: 826 AKES----PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEE 861
Score = 43.5 bits (101), Expect = 2e-04
Identities = 63/308 (20%), Positives = 102/308 (33%), Gaps = 52/308 (16%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPT-SRGHRTEKRKPQ 90
P+ P + P+ G+ S S + + D E A APA S G+ + +
Sbjct: 446 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 505
Query: 91 QPQRRPAGGTG--------QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKP 142
P + P G ++ S SS + + D EE AA T++ + + P
Sbjct: 506 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM---TAAQAKPALKIP 562
Query: 143 QQPQCRPAAGTG---------------QRRGSGCSPS----------------ADQQRAQ 171
Q C T ++ G+ SP+ +
Sbjct: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 622
Query: 172 DREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSR 231
D EEE T V K +++ P G+ + + P + T Q + +
Sbjct: 623 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT-QVKAEK 681
Query: 232 SSPSADQQRAQDREEEAAQPQ--RRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
S + D EE AA P + T + AAA P+ +GT +AP
Sbjct: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA------KGTISAPGKV 735
Query: 290 STGTGQRR 297
T Q +
Sbjct: 736 VTAAAQAK 743
Score = 42.4 bits (98), Expect = 5e-04
Identities = 56/292 (19%), Positives = 97/292 (33%), Gaps = 20/292 (6%)
Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 88
+TK +P++ + + + ++ + Q A + + AA AP R +
Sbjct: 252 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR-KGAA 310
Query: 89 PQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRK-PQQPQC 147
P P + + G R S D EEEA A P+ + P +
Sbjct: 311 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
Query: 148 RPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
R A R +G P+A Q + +EE++ ++ S R Q +P G +
Sbjct: 371 RKGAAPAPPRKTG--PAAAQVQVGKQEEDSRSSS-EESDSDREALAAMNAAQVKPLGKSP 427
Query: 208 QRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAA 267
Q + + + G G + P+ + EE++ + + TA
Sbjct: 428 QVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 487
Query: 268 APV------------PTTG---GTGQRRGTAAAPAPTSTGTGQRRGSEEMEE 304
AP PT+ G Q+ G A SEE +
Sbjct: 488 APAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 539
Score = 41.2 bits (95), Expect = 0.001
Identities = 58/246 (23%), Positives = 85/246 (34%), Gaps = 27/246 (10%)
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
Q+ ++ EEE+ + A S K Q + PA +R+ S+ A +
Sbjct: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA-------ARAPSAKGTISAPGK 734
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS-----ADQQRAQDREE 175
AAA S K + P P T RG PS A +AQ E
Sbjct: 735 VVTAAAQAKQRSPS------KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
Query: 176 EATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPS 235
E + + S +E+ Q +P+G T Q R + + P G ++ PS
Sbjct: 789 EDSGSSEEESD---SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPS 845
Query: 236 ADQQRAQD----REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTST 291
A Q QD EE+ PA T + P+ G AA PA
Sbjct: 846 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ--VIKPPLIFVDPNRSPAGPAATPAQAQA 903
Query: 292 GTGQRR 297
+ R+
Sbjct: 904 ASTPRK 909
Score = 34.3 bits (77), Expect = 0.14
Identities = 57/276 (20%), Positives = 110/276 (39%), Gaps = 36/276 (13%)
Query: 17 ESSEGD------QWLENEKTKPLRP--QQQPQCQPAGGTGQRRGSGSSPSADQQGAQD-R 67
ESSE D L T L P Q + P + S + D G Q+ +
Sbjct: 1112 ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1171
Query: 68 EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSAD------QQGAQDRE 121
++AA +P + G Q R+P G G + S + ++ Q E
Sbjct: 1172 PQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNE 1231
Query: 122 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTG----QRRGSGCSPSADQQRAQDREE-- 175
+ A+ + ++RK + ++ G +R+ SG P+A R++ +++
Sbjct: 1232 AQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLG 1291
Query: 176 -----EATAAPVPTSSGHRTE-KRKRLQLQCQPAGGTGQ--RRGSRSSPSRQPAGGTGQ- 226
EA+ +P TS+ + + KR + + G G +G++ P + G G
Sbjct: 1292 AGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTV 1351
Query: 227 RRGSRSSPSADQQ------RAQDREEEAAQPQRRPA 256
G +S+P + ++ R +D+E++ + + + A
Sbjct: 1352 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKA 1387
Score = 32.3 bits (72), Expect = 0.54
Identities = 27/128 (21%), Positives = 57/128 (44%), Gaps = 14/128 (10%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1282 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1334
Query: 63 GAQDREEEAAAAPAPTSRG-------HRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQ 115
GA+D EE T G + EK+K + ++ +++ ++S+ +
Sbjct: 1335 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1394
Query: 116 GAQDREEE 123
+Q ++++
Sbjct: 1395 PSQKKKKK 1402
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 52.4 bits (124), Expect = 5e-07
Identities = 50/260 (19%), Positives = 94/260 (36%), Gaps = 11/260 (4%)
Query: 50 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH---RTEKRKPQQPQRRPAGGTGQRRGS 106
R SGSS S+ + + + SR R++K K + P + + G
Sbjct: 205 RSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGK 264
Query: 107 RSSSSADQQGAQDREEEAAAAPAPTS-SGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSA 165
S S DQ + + + P S S H+++ + + Q R ++RGS
Sbjct: 265 SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEE--EKRGS-----V 317
Query: 166 DQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTG 225
+ R+Q++ + + + G R+ R R + + + G R SRS +
Sbjct: 318 SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS 377
Query: 226 QRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAA 285
++RGS+ A + + +E+ R P+ + R A + G G+
Sbjct: 378 RKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTN 437
Query: 286 PAPTSTGTGQRRGSEEMEEE 305
S + + E
Sbjct: 438 QETRSRSRSNSKSKPNLPSE 457
Score = 50.4 bits (119), Expect = 2e-06
Identities = 51/267 (19%), Positives = 107/267 (40%), Gaps = 23/267 (8%)
Query: 46 GTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRG 105
G+ +RR S S + ++ R + + + +S+ ++ R + R + R
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 106 SRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSA 165
SRS S ++ + +E+ + + + S +++ + ++ Q G + R SPS
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR----SPSR 293
Query: 166 DQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTG 225
+ +++ R S R E+ KR + + G Q + R S SR + G
Sbjct: 294 HKSKSKSRSR---------SQERRVEEEKRGSV----SRGRSQEKSLRQSRSRSRSKGGS 340
Query: 226 QRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGT------GQRRGTAAAPVPTTGGTGQR 279
+ R S S D+++ + R E ++ + R + G +R + A
Sbjct: 341 RSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
Query: 280 RGTAAAPAPTSTGTGQRRGSEEMEEEG 306
R + +P+ + + + SE + EG
Sbjct: 401 RSQSRSPSRSVSKEREHAKSESSQREG 427
Score = 37.7 bits (86), Expect = 0.013
Identities = 47/245 (19%), Positives = 92/245 (37%), Gaps = 17/245 (6%)
Query: 2 KPRQKEQDTRLRKLRESSE-GDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
K R K +D K++ + G + + + + + Q ++RGS S +
Sbjct: 264 KSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQ 323
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
++ + + + SR K K ++ R+ + R SRS S + + + R
Sbjct: 324 EKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS-----REESRSRSRSRSKSERSR 378
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCR-PAAGTGQRRGSGCSPSADQQRAQDREEEATA 179
+ + + S + +K + Q R P+ + R S S+ ++ + E T
Sbjct: 379 -KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT- 436
Query: 180 APVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQ 239
T R R + +P + R S+S+ + + R SR SPS +
Sbjct: 437 -------NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASR-SPSRSRS 488
Query: 240 RAQDR 244
R+ R
Sbjct: 489 RSHSR 493
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 52.4 bits (124), Expect = 5e-07
Identities = 64/269 (23%), Positives = 95/269 (35%), Gaps = 45/269 (16%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
RP QP PA P Q G E + + A ++ H ++ +K
Sbjct: 3680 RPHSQPSSAPA-----------MPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK----- 3723
Query: 94 RRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGT 153
G G + S + AQ + + AAP P S + ++ P R
Sbjct: 3724 ----GSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQ 3779
Query: 154 GQRRGSGCSP---SADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRR 210
Q++G G P + Q R Q + + T P +S QPAG +
Sbjct: 3780 QQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAAS--------------QPAGKP--QP 3823
Query: 211 GSRSSPSRQPAGG--TGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRR--GTA 266
G ++ QPAG Q GS+ + A QQ + + A P PAG R GT
Sbjct: 3824 GPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGP--GPAGVKAGARPGGTP 3881
Query: 267 AAPVPTTGGTGQRRGTAAAPAPTSTGTGQ 295
AP G G+ + P + G+
Sbjct: 3882 GAPAGQPGADGESVFSKILPGGAAEQAGK 3910
Score = 40.8 bits (94), Expect = 0.002
Identities = 75/332 (22%), Positives = 109/332 (32%), Gaps = 77/332 (23%)
Query: 43 PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQ 102
P G G G+G PSA G Q AA A S P P G+
Sbjct: 23 PGPGPGPGPGAGKPPSAPAGGGQ-----LPAAGAARSTAVPPVPGPGPGPGPGPGPGSTS 77
Query: 103 RRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKR-KPQQPQCRPAAG-------TG 154
RR +Q+ A ++A+A T+ GH + + + Q P + A G
Sbjct: 78 RRLDPKEPLGNQRAASPTPKQASA----TTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
Query: 155 QRRGSGCSPSADQQRAQDREEEATA---APVPTS-------------------------- 185
+ + SG SPS R + AP+P+S
Sbjct: 134 RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQC 193
Query: 186 ------------SGHRTEKRKRLQLQC--QPAGGTGQRRGSRS---------------SP 216
+ H T+ ++ L L C Q A G RS SP
Sbjct: 194 HNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSP 253
Query: 217 SRQPAGGTGQRRG-SRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGG 275
++QP G Q R P ++A+ + + A R + P PT
Sbjct: 254 AKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPS 313
Query: 276 TGQRRGTAA-APAPTSTGTGQRRGSEEMEEEG 306
T + R A APA ++T G+ E +EG
Sbjct: 314 TAEPRPPAGEAPAKSATAVPAGLGATEQTQEG 345
Score = 36.6 bits (83), Expect = 0.029
Identities = 59/253 (23%), Positives = 86/253 (33%), Gaps = 36/253 (14%)
Query: 52 GSGSSPSADQ--QGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ----RRPAGGTGQRRG 105
GS ++PS+ + + A++ EE + E + QQ Q R P GG Q G
Sbjct: 1170 GSSTTPSSGRPLKSAEEAYEEMM---------RKAELLQRQQGQAAGARGPHGGPSQPTG 1220
Query: 106 SRSSSSADQQGAQDREEEAAAAPA----PTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGC 161
R S + Q DRE AA PA P S G + Q Q R
Sbjct: 1221 PRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAF 1280
Query: 162 SPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPA 221
+ +++ E A P+ + G T QL S S+P+
Sbjct: 1281 AEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPV---------SFSTPT---- 1327
Query: 222 GGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRG 281
+ G R P D + Q +E P + + + +P + G G
Sbjct: 1328 --SSDSSGGRVIP--DVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPAT 1383
Query: 282 TAAAPAPTSTGTG 294
TA AP P G
Sbjct: 1384 TAVAPCPAGLPRG 1396
Score = 34.7 bits (78), Expect = 0.11
Identities = 51/229 (22%), Positives = 80/229 (34%), Gaps = 35/229 (15%)
Query: 58 SADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP-QRRPAGGTGQRRGSRSSSSADQQG 116
+A + +Q + A +PA H K+ +P Q R G G + GSR + +A
Sbjct: 232 TAPRSKSQQQLHSPALSPA-----HSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATS 286
Query: 117 AQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEE 176
+ AA S + KP + RP AG +
Sbjct: 287 VPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAK------------------- 327
Query: 177 ATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSA 236
+A VP G + ++ L + G + + S + A GQ S+ +P
Sbjct: 328 -SATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKI 386
Query: 237 ---DQQRAQDREEEAAQPQRRPAGGT----GQRRGTAAAP--VPTTGGT 276
D + + + P PA G G R G + P +P TGGT
Sbjct: 387 VFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGT 435
Score = 33.1 bits (74), Expect = 0.32
Identities = 50/238 (21%), Positives = 87/238 (36%), Gaps = 18/238 (7%)
Query: 53 SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG----TGQRRGSRS 108
SG+SP++ EE++ ++P SR R E+ K Q+ R + G T +
Sbjct: 992 SGTSPTS----LSSLEEDSDSSP---SRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEE 1044
Query: 109 SSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQ 168
+++ +++E+ S R +R ++ + + + S SP D
Sbjct: 1045 ELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDAS 1104
Query: 169 RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPA-----GG 223
++ + A + SS L + + G R S P
Sbjct: 1105 PTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSP 1164
Query: 224 TGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRG 281
T GS ++PS+ R EEA + R A +++G AA GG Q G
Sbjct: 1165 TETPSGSSTTPSSG--RPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTG 1220
Score = 32.0 bits (71), Expect = 0.70
Identities = 50/218 (22%), Positives = 71/218 (32%), Gaps = 29/218 (13%)
Query: 96 PAGGTGQRRGSRSSSSADQQGAQDREEEA---------AAAPAPTSSGHRTEKRKPQQPQ 146
P G G+ R S S +Q Q A AAAPA S ++ + Q P
Sbjct: 3001 PLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPA 3060
Query: 147 CRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGT 206
+ +AG+G +G A Q A P + + E Q +P T
Sbjct: 3061 PQYSAGSGGPTQNGFP--AHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRP---T 3115
Query: 207 GQRRGSRSSPSRQ------PAGGTGQRRGSRSSPSADQQRAQDREEE---------AAQP 251
G G P+ Q PA + R + AD ++ E ++ P
Sbjct: 3116 GHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAP 3175
Query: 252 QRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
G G VP G R + +PAPT
Sbjct: 3176 SETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPT 3213
Score = 30.8 bits (68), Expect = 1.6
Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 12/86 (13%)
Query: 210 RGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAP 269
RG R P P G G+ R S +Q R Q A Q PA TAAAP
Sbjct: 2994 RGGRDYP---PLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPA--------TAAAP 3042
Query: 270 VPTTGGTGQRRGTAAAPAPT-STGTG 294
+G T ++ PAP S G+G
Sbjct: 3043 ATPSGPTAFQQPRFQPPAPQYSAGSG 3068
Score = 30.4 bits (67), Expect = 2.0
Identities = 25/76 (32%), Positives = 26/76 (34%), Gaps = 20/76 (26%)
Query: 220 PAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGG-----TGQRRGTAAAPVPTTG 274
P GG G G P A +P PAGG G R TA PVP
Sbjct: 17 PPGGAGPGPGPGPGPGA------------GKPPSAPAGGGQLPAAGAARSTAVPPVP--- 61
Query: 275 GTGQRRGTAAAPAPTS 290
G G G P TS
Sbjct: 62 GPGPGPGPGPGPGSTS 77
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 52.0 bits (123), Expect = 7e-07
Identities = 61/264 (23%), Positives = 94/264 (35%), Gaps = 16/264 (6%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ-PQRRPAGGT 100
Q G+GQ G S + + + + A +S H + R+ Q A
Sbjct: 350 QHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRH 409
Query: 101 GQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSG 160
RG SS S G R + +P+ G + P +G+G G G
Sbjct: 410 SSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPY---VSGSGYSSGFG 466
Query: 161 CSPSADQQRAQDREEEATAAPVPTSSGH-----RTEKRKRLQLQCQPAGGTGQRRGSRSS 215
S+ + + + + + SSGH R+ + R + Q AG + G S
Sbjct: 467 HHESSSEHSSGYTQHGSGSGH---SSGHGQHGSRSGQSSRGERQGSSAGSSSSY-GQHGS 522
Query: 216 PSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGG 275
SRQ G + GS SPS + R E + Q G G R ++ P + G
Sbjct: 523 GSRQSLGHSRHGSGSGQSPSPSRGR---HESGSRQSSSYGPHGYGSGRSSSRGPYESGSG 579
Query: 276 TGQRRGTAAAPAPTSTGTGQRRGS 299
G + + S+G GQ S
Sbjct: 580 HSSGLGHQESRSGQSSGYGQHGSS 603
Score = 47.8 bits (112), Expect = 1e-05
Identities = 64/280 (22%), Positives = 103/280 (36%), Gaps = 32/280 (11%)
Query: 46 GTGQR-RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
G GQR GSG SPS + G+ ++ S K Q +G T
Sbjct: 892 GHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQS--SGYTQHGS 949
Query: 105 GSRSSSSADQQGAQD-----REEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQ---- 155
GS SSS +Q G++ E+ +++ + +S G + + +G+GQ
Sbjct: 950 GSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009
Query: 156 ---RRGSGCSPSADQQRAQDREE-EATAAPVPTSSGHRTEKRKRLQLQCQPAG------- 204
R GSG S+ + ++ P + SGH + R Q +G
Sbjct: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS 1069
Query: 205 -GTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQ-- 261
G G S S Q + GQ S S+ Q + + R G+GQ
Sbjct: 1070 SGHSSTHGQHGSTSGQ-SSSCGQHGASSGQSSSHGQHGSGSSQSSGYG--RQGSGSGQSP 1126
Query: 262 ---RRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRG 298
+RG+ + P+ G G G +++ +G G+ G
Sbjct: 1127 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG 1166
Score = 47.8 bits (112), Expect = 1e-05
Identities = 61/284 (21%), Positives = 98/284 (34%), Gaps = 40/284 (14%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTG 101
Q +G Q GSG SPS + G+ + S R+ R P + + + G
Sbjct: 1228 QSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHG--SGSGRSSSRGPYESRSGHSSVFG 1285
Query: 102 QRR-GSRSSSSADQQGAQDR------------------EEEAAAAPAPTSSGHRTEKRKP 142
Q GS SS+ Q G+ ++E ++ +S GHR
Sbjct: 1286 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ 1345
Query: 143 QQPQCRPAAGTGQ-----RRGSGCSPSADQQR-------AQDREEEATAAPVPTSSGHRT 190
R AG+GQ R GSG S+ + + + + + GH
Sbjct: 1346 SSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 1405
Query: 191 EKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQ 250
+ Q G+G SR G+R GS S S+ +
Sbjct: 1406 SSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG-------QHGS 1458
Query: 251 PQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTG 294
R+ G G+ +P P+ G G G +++ +P +G+G
Sbjct: 1459 GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG 1502
Score = 47.4 bits (111), Expect = 2e-05
Identities = 66/312 (21%), Positives = 110/312 (35%), Gaps = 35/312 (11%)
Query: 16 RESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRR-GSGSSPSADQQGAQDREEEAAAA 74
R+SS Q + R Q + G GQR GSG SPS+ Q G +++
Sbjct: 395 RQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGT-GFGRSSSSG 453
Query: 75 PAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQD-----REEEAAAAPA 129
P + G+ + + +G T GS SS Q G++ E + ++A +
Sbjct: 454 PYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGS 513
Query: 130 PTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDRE------------EEA 177
+S G + R +G+GQ SPS + + R+ +
Sbjct: 514 SSSYGQHGSGSRQSLGHSRHGSGSGQ----SPSPSRGRHESGSRQSSSYGPHGYGSGRSS 569
Query: 178 TAAPVPTSSGHRTEKRKRLQLQCQPAG--------GTGQRRGSRSSPSRQPAGGTGQRRG 229
+ P + SGH + + Q +G G G S S Q + GQ
Sbjct: 570 SRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQ-SSSCGQHGA 628
Query: 230 SRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQR---RGTAAAP 286
+ S+ Q + + Q+ G RG + + GQ G +++
Sbjct: 629 TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSN 688
Query: 287 APTSTGTGQRRG 298
P + +GQ G
Sbjct: 689 GPHGSVSGQSSG 700
Score = 47.0 bits (110), Expect = 2e-05
Identities = 61/280 (21%), Positives = 104/280 (37%), Gaps = 35/280 (12%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDRE-----EEAAAAPAPTSRGHRTEKRKPQQPQRRP 96
Q +G Q GSG SPS + G+ + + +S GH +
Sbjct: 761 QSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQH 820
Query: 97 AGGTGQ---RRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGT 153
G+GQ + GS S + Q +++++ SS ++ + A+G
Sbjct: 821 ESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGR 880
Query: 154 GQR-RGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG- 211
G+ GSG SP Q+ + + S G R + G+GQ G
Sbjct: 881 GRHGSGSGQSPGHGQRGSGSGQSP--------SYGRHGSGSGRSSSSGRHGSGSGQSSGF 932
Query: 212 SRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAG--------GTGQRR 263
S S Q +G T GS S S +Q ++ + ++ +G G+G R+
Sbjct: 933 GHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQ 992
Query: 264 ---------GTAAAPVPTTGGTGQRRGTAAAPAPTSTGTG 294
G+ +P P+ G G G +++ P +G+G
Sbjct: 993 SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSG 1032
Score = 45.8 bits (107), Expect = 5e-05
Identities = 56/272 (20%), Positives = 89/272 (32%), Gaps = 27/272 (9%)
Query: 46 GTGQRRGSGSSPSADQQG-AQDREEEAAAAPAPTSRGHRTEKRKPQQP---QRRPAGGTG 101
G+G + S SP G + R + + + GHR E R Q Q + G
Sbjct: 1485 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHR-ESRSGQSSGYGQHGSSSGHS 1543
Query: 102 QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGC 161
G S+S + A++ +S G R +G+GQ G G
Sbjct: 1544 STHGQHGSTSGQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1600
Query: 162 SPSADQQ------------RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQR 209
S +Q R+ + + + GH + Q G+G
Sbjct: 1601 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1660
Query: 210 RGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAP 269
G SR G+R GS S R+ R + R+ +G Q G+ +P
Sbjct: 1661 SGYGQHGSRSGQSSRGERHGSSS-------RSSSRYGQHGSGSRQSSGHGRQGSGSGQSP 1713
Query: 270 VPTTGGTGQRRGTAAAPAPTSTGTGQRRGSEE 301
G+G ++ + +G RG E
Sbjct: 1714 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1745
Score = 43.5 bits (101), Expect = 2e-04
Identities = 57/284 (20%), Positives = 96/284 (33%), Gaps = 40/284 (14%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTG 101
Q +G Q GSG SPS + G+ + S R+ R P + + + G
Sbjct: 2168 QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHG--SGSGRSSSRGPYESRSGHSSVFG 2225
Query: 102 QRR-GSRSSSSADQQGAQDR------------------EEEAAAAPAPTSSGHRTEKRKP 142
Q GS SS+ Q G+ ++E ++ +S G
Sbjct: 2226 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 2285
Query: 143 QQPQCRPAAGTGQ-----RRGSGCSPSADQQR-------AQDREEEATAAPVPTSSGHRT 190
+ +G+GQ R GSG S+ + + + + + GH
Sbjct: 2286 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 2345
Query: 191 EKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQ 250
+ Q G+G SR G+R GS S S+ +
Sbjct: 2346 SSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG-------QHGS 2398
Query: 251 PQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTG 294
R+ G G+ +P P+ G G G +++ +P +G+G
Sbjct: 2399 GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG 2442
Score = 43.5 bits (101), Expect = 2e-04
Identities = 55/266 (20%), Positives = 90/266 (33%), Gaps = 29/266 (10%)
Query: 46 GTGQRRGSGSSPSADQQG-AQDREEEAAAAPAPTSRGHRTEKRKPQQP---QRRPAGGTG 101
G+G + S SP G + R + + + GHR E R Q Q + G
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHR-ESRSGQSSGYGQHGSSSGHS 2483
Query: 102 QRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGC 161
G S+S + A++ +S G R +G+GQ G G
Sbjct: 2484 STHGQHGSTSGQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 2540
Query: 162 SPSADQQ------------RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQR 209
S +Q R+ + + + GH + Q G+G
Sbjct: 2541 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 2600
Query: 210 RGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAP 269
G SR G+R GS S S+ + R + G G R+G+ +
Sbjct: 2601 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS--------RQSSGHG-RQGSGSGQ 2651
Query: 270 VPTTGGTGQRRGTAAAPAPTSTGTGQ 295
P+ G G G +++ +G+G+
Sbjct: 2652 SPSRGRHGSGLGHSSSHGQHGSGSGR 2677
Score = 43.1 bits (100), Expect = 3e-04
Identities = 68/292 (23%), Positives = 105/292 (35%), Gaps = 41/292 (14%)
Query: 42 QPAGGTGQ-----RRGSGS--SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR 94
Q G+GQ R GSGS S S Q G+ ++ S G + +
Sbjct: 2291 QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS-GQSSGFGHHESSSW 2349
Query: 95 RPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTG 154
+ +G T GS SSS +Q G+ R +++ SS + R + G G
Sbjct: 2350 QSSGYTQHGSGSGHSSSYEQHGS--RSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407
Query: 155 QR-RGSGCSPSADQQRAQDREEEATA--------------APVPTSSGHRTEKRKRLQLQ 199
Q GSG SPS + R ++++ P + SGH + R
Sbjct: 2408 QHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS 2467
Query: 200 CQPAG--------GTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQP 251
Q +G G G S S Q + GQ S S+ Q + +
Sbjct: 2468 GQSSGYGQHGSSSGHSSTHGQHGSTSGQ-SSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 2526
Query: 252 QRRPAGGTGQ-----RRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRG 298
R G+GQ +RG+ + P+ G G G +++ +G G+ G
Sbjct: 2527 --RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG 2576
Score = 42.7 bits (99), Expect = 4e-04
Identities = 63/305 (20%), Positives = 112/305 (36%), Gaps = 31/305 (10%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTG-QRRGSGSSPSADQQGAQDREEEAAAAP 75
+SS G++ + ++ Q + + G G Q GSG SPS + G+ +
Sbjct: 1672 QSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQH 1731
Query: 76 APTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGH 135
S R+ R P + + + GQ SSA Q + ++SG
Sbjct: 1732 G--SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 1789
Query: 136 RTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQ-QRAQDREEEATAAPVPTSSGHRTEKRK 194
+ Q+ + + + GSG S S+ Q+ + + + SGH + +
Sbjct: 1790 SSTF--DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ 1847
Query: 195 R------LQLQCQPAGGTGQRRG--SRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREE 246
+ G+GQ G S S Q +G T GS S S +Q ++ +
Sbjct: 1848 HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS 1907
Query: 247 EAAQPQRRPAG--------GTGQRR---------GTAAAPVPTTGGTGQRRGTAAAPAPT 289
+ +G G+G R+ G+ +P P+ G G G +++ P
Sbjct: 1908 SRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY 1967
Query: 290 STGTG 294
+G+G
Sbjct: 1968 GSGSG 1972
Score = 42.4 bits (98), Expect = 5e-04
Identities = 65/290 (22%), Positives = 102/290 (35%), Gaps = 34/290 (11%)
Query: 49 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRS 108
Q GSG SPS + G+ D ++ + G + P + G G + GS
Sbjct: 652 QGSGSGQSPSRGRHGS-DFGHSSSYGQHGSGSGW-SSSNGPHGSVSGQSSGFGHKSGSGQ 709
Query: 109 SSSADQQGAQD-----------REEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTG-QR 156
SS Q G+ R +++ + SS + ++G G Q
Sbjct: 710 SSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQG 769
Query: 157 RGSGCSPS-----ADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
GSG SPS + + + + +S GH + Q G+GQ
Sbjct: 770 SGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYS 829
Query: 212 SRSSPSRQ--PAGGTGQRRGSRSSP-----SADQQRAQDREEEA---AQPQRRPAGGTGQ 261
S S G G G SS S+ Q + + E A A + R G+GQ
Sbjct: 830 QHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ 889
Query: 262 -----RRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEEG 306
+RG+ + P+ G G G +++ +G+GQ G G
Sbjct: 890 SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSG 939
Score = 41.6 bits (96), Expect = 9e-04
Identities = 56/279 (20%), Positives = 96/279 (34%), Gaps = 34/279 (12%)
Query: 42 QPAGGTGQ-------RRGSGSSPSADQQGAQDREE-EAAAAPAPTSRGHRTEKRKPQQPQ 93
Q G+GQ R GSGS S+ + ++ P + GH + +
Sbjct: 998 QHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRS 1057
Query: 94 RRPAGGTGQRRGSRSSSSADQQGAQDRE-----EEAAAAPAPTSSGHRTEKRKPQQPQCR 148
+ +G S SS+ Q G+ + + A++ +S G R
Sbjct: 1058 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 1117
Query: 149 PAAGTGQRRGSGCSPSADQQ------------RAQDREEEATAAPVPTSSGHRTEKRKRL 196
+G+GQ G G S +Q R+ + + + GH +
Sbjct: 1118 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 1177
Query: 197 QLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPA 256
Q G+G G SR G+R GS S S+ + R +
Sbjct: 1178 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS--------RQS 1229
Query: 257 GGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQ 295
G G R+G+ + P+ G G G +++ +G+G+
Sbjct: 1230 SGHG-RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGR 1267
Score = 39.7 bits (91), Expect = 0.003
Identities = 58/295 (19%), Positives = 96/295 (32%), Gaps = 43/295 (14%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDRE------------------EEAAAAPAPTSRGHR 83
Q +G Q GSG SP Q+G+ R+ + + + GH
Sbjct: 1581 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1640
Query: 84 TEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQ 143
+ G+G G S Q ++ E +++ + + G +
Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG-ERHGSSSRSSSRYGQHGSGSRQS 1699
Query: 144 QPQCRPAAGTGQ-----RRGSGCSPSADQ-QRAQDREEEATAAPVPTSSGHRT------E 191
R +G+GQ R GSG S+ Q ++ P + SGH +
Sbjct: 1700 SGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 1759
Query: 192 KRKRLQLQCQPAGGTGQ-----RRGSRSSPSR---QPAGGTGQRRGSRSSPSADQQRAQD 243
Q G+G + GS S S Q TGQ S Q +
Sbjct: 1760 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSY 1819
Query: 244 REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRG 298
++ + Q G R G+ + + G G G +++ +G+GQ G
Sbjct: 1820 GQQGSGSGQSPSRG----RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG 1870
Score = 37.0 bits (84), Expect = 0.022
Identities = 57/295 (19%), Positives = 94/295 (31%), Gaps = 43/295 (14%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDRE------------------EEAAAAPAPTSRGHR 83
Q +G Q GSG SP Q+G+ R+ + + GH
Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH 2110
Query: 84 TEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQ 143
+ G+G G S Q ++ E +++ + + G +
Sbjct: 2111 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG-ERHGSSSGSSSRYGQHGSGSRQS 2169
Query: 144 QPQCRPAAGTGQ-----RRGSGCSPSADQ-QRAQDREEEATAAPVPTSSGHRT------E 191
R +G+G R GSG S+ Q ++ P + SGH +
Sbjct: 2170 SGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 2229
Query: 192 KRKRLQLQCQPAGGTGQ-----RRGSRSSPSR---QPAGGTGQRRGSRSSPSADQQRAQD 243
Q G+G + GS S S Q TGQ S Q +
Sbjct: 2230 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSY 2289
Query: 244 REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRG 298
++ + Q G R G+ + + G G G +++ +G+GQ G
Sbjct: 2290 GQQGSGSGQSPSRG----RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG 2340
Score = 36.6 bits (83), Expect = 0.029
Identities = 45/232 (19%), Positives = 75/232 (32%), Gaps = 12/232 (5%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQR 103
+ G GQ S S Q + ++ S G + + + +G Q
Sbjct: 2000 SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
Query: 104 RGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSP 163
GS S Q+G+ R+ + S R+ P ++G G S
Sbjct: 2060 SGSGQSPGHGQRGSGSRQSPSYGRHG--SGSGRSSSSGQHGPGLGESSGFGHHESSSGQS 2117
Query: 164 SADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGG 223
S+ Q + + SG + + + G+ R G S SRQ +G
Sbjct: 2118 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH-----GSSSGSSSRYGQHGSGSRQSSGH 2172
Query: 224 TGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGG 275
Q GS SPS + + + G+G R ++ P + G
Sbjct: 2173 GRQGSGSGHSPSRGRHGS-----GSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
Score = 35.8 bits (81), Expect = 0.049
Identities = 56/292 (19%), Positives = 91/292 (31%), Gaps = 21/292 (7%)
Query: 14 KLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA 73
KLR+ + Q + E K +Q+ S SS SA + + R +
Sbjct: 100 KLRDDTHQHQEEQEETEKEENKRQESSF-----------SHSSWSAGENDSYSRNVRGSL 148
Query: 74 APAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSS 133
P S R ++ Q G G ++S S G + +P
Sbjct: 149 KPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQH 208
Query: 134 GHRTEKRKPQQPQ---CRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRT 190
G + + ++G Q + S S Q + + SG +
Sbjct: 209 GSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSS 268
Query: 191 EKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQ 250
+ + + G+ G S SRQ G Q GSR SPS + ++
Sbjct: 269 RGERH-----RSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPS-HVRHGSGSGHSSSH 322
Query: 251 PQRRPAGGTGQRRGTAAAPVPTTGGTGQRR-GTAAAPAPTSTGTGQRRGSEE 301
Q RG + T G GQ G+ + + G+G S +
Sbjct: 323 GQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQ 374
Score = 35.8 bits (81), Expect = 0.049
Identities = 57/291 (19%), Positives = 98/291 (33%), Gaps = 41/291 (14%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDRE------------------EEAAAAPAPTSRGHR 83
Q +G Q GSG SP Q+G+ R+ + + + GH
Sbjct: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580
Query: 84 TEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQ 143
+ G+G G S Q ++ E +++ + + G +
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG-ERHGSSSGSSSHYGQHGSGSRQS 2639
Query: 144 QPQCRPAAGTGQ-----RRGSGCSPSADQ-QRAQDREEEATAAPVPTSSGHRT------E 191
R +G+GQ R GSG S+ Q ++ P + GH +
Sbjct: 2640 SGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHES 2699
Query: 192 KRKRLQLQCQPAGGTGQ--RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAA 249
Q G+G +G S S Q T + GS + S+ +++
Sbjct: 2700 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ--SSTFDQEGSSTGQSSSYGHRGSGSSQSS 2757
Query: 250 QPQRRPAGGTGQ-----RRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQ 295
R A G+GQ R G+ + + G G G ++ + +G+GQ
Sbjct: 2758 GYGRHGA-GSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQ 2807
>gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
sapiens]
Length = 351
Score = 51.6 bits (122), Expect = 9e-07
Identities = 54/233 (23%), Positives = 89/233 (38%), Gaps = 26/233 (11%)
Query: 56 SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ-----PQRRPAGGTG-QRRGSRSS 109
SP + G + R E+ AP ++ R + PQ R G +RRG +++
Sbjct: 94 SPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAA 153
Query: 110 SSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQR 169
S G + R ++AA A A + RKP++ R AA G++ Q+
Sbjct: 154 KSRGGGGKKPRGQKAAGAGAK-------KHRKPRRRGERAAAAGGKKL----------QK 196
Query: 170 AQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRG 229
A + ++G + +R+R Q + GG G ++ R + G ++
Sbjct: 197 AAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGG-GDKKLERQKAALTGVKSRGDKKP 255
Query: 230 SRSSPSADQ--QRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRR 280
R + Q + R +PQ+ A G R G P G GQ R
Sbjct: 256 LRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308
Score = 33.5 bits (75), Expect = 0.24
Identities = 59/231 (25%), Positives = 87/231 (37%), Gaps = 47/231 (20%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQ--RRGSGSSPSA 59
+PR++E TR R D + RPQ + GG + RRG ++ S
Sbjct: 103 EPRRRESWTRSAP-RRCPYQDASRAGSRVCRSRPQNR-----GGGDKKPRRRGQKAAKSR 156
Query: 60 DQQGAQDREEEAAAAPA-----PTSRGHRTEKRKPQQPQRRPA----GGTGQR------- 103
G + R ++AA A A P RG R ++ Q+ A GG G++
Sbjct: 157 GGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGK 216
Query: 104 --RGSRSSSSADQQGAQDR--EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGS 159
R R +A +G D+ E + AA S G + R ++ + R T R G
Sbjct: 217 KPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRER-GQNTKSRGGG 275
Query: 160 GCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRR 210
G P + AA S G R EK ++ + G GQ R
Sbjct: 276 GEKP------------QKAAAAGAKSRGGRGEKPQKAE------AGQGQNR 308
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/286 (23%), Positives = 103/286 (36%), Gaps = 43/286 (15%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 91
P RP + + +PA G+ A + A P PT G E R+ ++
Sbjct: 614 PHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKER 673
Query: 92 PQRRP-------AGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQ 144
P R P G+G SSS + + ++A + +SS H +
Sbjct: 674 PARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYA 733
Query: 145 PQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKR------LQL 198
P + R SP+ AQ R+E+ + G + EKRKR +
Sbjct: 734 DLASPVSSASSR-----SPAP----AQTRKEKGKS---KKEDGVKEEKRKRDSSTQPPKS 781
Query: 199 QCQPAGGTGQRRGS--RSSPSRQPAGGTG-----------QRRGSRSSPSADQQRAQDRE 245
PAGG ++ S + +P QP GT + + S + +DR+
Sbjct: 782 AKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQ 841
Query: 246 E--EAAQPQRRPAGGTGQRR--GTAAAPVPTTGGTGQRRGTAAAPA 287
A +P P G+ R+ G +P P GQ AAPA
Sbjct: 842 SPPPAKRPNTSPDRGSRDRKSGGRLGSPKPER-QRGQNSKAPAAPA 886
Score = 50.8 bits (120), Expect = 1e-06
Identities = 68/334 (20%), Positives = 117/334 (35%), Gaps = 52/334 (15%)
Query: 5 QKEQDTRLRKLRESSEGDQWLENEKTK---------PLRPQQQPQCQPAGGTG------- 48
++E+ R K R+ + D+ E EK K P Q +P + A TG
Sbjct: 454 ERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRAD 513
Query: 49 -------------QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 95
++ G SPS ++ + A+A+ + S + + R
Sbjct: 514 EWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSR 573
Query: 96 PAGGTGQRRGSRSSSSADQQGAQDREEEAAA--APAPTSSGHRTEKRKPQQPQCRPAAGT 153
+ SRSS + G++ R ++ +P+PT S HR R +P P
Sbjct: 574 SRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAG 633
Query: 154 GQRRGSGCSPSADQQRAQDREEEATAAPV--PTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
+ P A Q + T APV PT G E R++ R
Sbjct: 634 EKSVKKPAPPPAPPQATK------TTAPVPEPTKPGDPREARRK-------------ERP 674
Query: 212 SRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVP 271
+R+ P R+ G+G GS S S+ + R+ ++ + + +
Sbjct: 675 ARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYAD 734
Query: 272 TTGGTGQRRGTAAAPAPTSTGTGQRRGSEEMEEE 305
+ APA T G+ + + ++EE
Sbjct: 735 LASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEE 768
Score = 42.7 bits (99), Expect = 4e-04
Identities = 50/260 (19%), Positives = 91/260 (35%), Gaps = 19/260 (7%)
Query: 49 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRS 108
+R +++ +DRE E R H E+ K +Q ++ +R +
Sbjct: 407 ERERENRQRERERERERDRERERRQREREREREH--ERDKERQRRKEEWERERAKRDEKD 464
Query: 109 SSSADQQGAQDREEEAA----AAPAPTS------------SGHRTEKRKPQQPQCRPAAG 152
D+ ++RE+E +P P S +G + ++ + R +
Sbjct: 465 RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKS 524
Query: 153 TGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGS 212
++ G SPS ++R + A+A+ SS + + + + S
Sbjct: 525 PKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSS 584
Query: 213 RSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPT 272
RSS +G + R SSPS + R + + P G + + P P
Sbjct: 585 RSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEK-SVKKPAPP 643
Query: 273 TGGTGQRRGTAAAPAPTSTG 292
+ TA P PT G
Sbjct: 644 PAPPQATKTTAPVPEPTKPG 663
Score = 30.4 bits (67), Expect = 2.0
Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 27/180 (15%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGT----GQRRGSGSSPSA 59
R+++ T+ K + G + +P PQQ P QP GT + + + + +A
Sbjct: 770 RKRDSSTQPPKSAKPPAGGK----SSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAA 825
Query: 60 DQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGA-- 117
D +G++ R E + + R+ P +RP T RGSR S + G+
Sbjct: 826 D-KGSRKRYEPS------------DKDRQSPPPAKRP--NTSPDRGSRDRKSGGRLGSPK 870
Query: 118 --QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREE 175
+ R + + A AP + + + G G+ + S REE
Sbjct: 871 PERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREE 930
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 51.2 bits (121), Expect = 1e-06
Identities = 70/293 (23%), Positives = 98/293 (33%), Gaps = 31/293 (10%)
Query: 32 PLRPQQQPQCQP-------AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPT-----S 79
P Q P P AG R+ G+S + QGA + E + T S
Sbjct: 999 PAALQSMPTLDPRLHRAATAGPPNARQRPGASTDSSTQGANLPDFELLSRILKTVNATGS 1058
Query: 80 RGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEK 139
KP P+ R A T R + S+A + A+ EA + A S
Sbjct: 1059 SAAPGSSDKPSDPRVRKAP-TDPRLQKPTDSTASSRAAKPGPAEAPSPTASPSGDASPPA 1117
Query: 140 RKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQ 199
P P+ A G GQ G G S D P + G TE Q
Sbjct: 1118 TAPYDPRVLAAGGLGQGGGGGQSSVLSGISLYDPR-------TPNAGGKATEPAADTGAQ 1170
Query: 200 CQPAGGTGQRRGS--------RSSPSRQPAGGTGQRRGSRSSP---SADQQRAQDREEEA 248
+ A G G+ S R S QP G G + S ++ R + A
Sbjct: 1171 PKGAEGNGKSSASKAKEPPFVRKSALEQPETGKAGADGGTPTDRYNSYNRPRPKAAAAPA 1230
Query: 249 AQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSEE 301
A P G + G PVPT GT ++ + +P + + R G ++
Sbjct: 1231 ATTATPPPEGAPPQPGVHNLPVPTLFGTVKQTPKTGSGSPFAGNSPAREGEQD 1283
Score = 38.5 bits (88), Expect = 0.008
Identities = 74/332 (22%), Positives = 114/332 (34%), Gaps = 61/332 (18%)
Query: 8 QDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAG-------GTGQRRGSGSSPSAD 60
+D RL + E+S G ++ + P + P +P G G +GSG P+ +
Sbjct: 866 RDPRLTRHVEASGGSGPGDSGPSDPRLARALPTSKPEGSLHSSPVGPSSSKGSGPPPTEE 925
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
++G + E+A P GH + Q Q + ++ S + +
Sbjct: 926 EEGERALREKAVNIPLDPLPGHPLRDPRSQLQQ-----FSHIKKDVTLSKPSFARTVLWN 980
Query: 121 EEEAAAAPAPTSSG------------------HRTEKRKPQQPQCRPAAGTGQRRGSGCS 162
E+ P P HR P + RP A T
Sbjct: 981 PEDLIPLPIPKQDAVPPVPAALQSMPTLDPRLHRAATAGPPNARQRPGASTDSSTQGANL 1040
Query: 163 PSADQQRAQDREEEAT-AAPVPTSSGHRTEKRKRL-----QLQCQPAGGTGQRRGSRSSP 216
P + + AT ++ P SS ++ R R +LQ +P T R ++ P
Sbjct: 1041 PDFELLSRILKTVNATGSSAAPGSSDKPSDPRVRKAPTDPRLQ-KPTDSTASSRAAKPGP 1099
Query: 217 SRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPV------ 270
+ P+ +SPS D A P+ AGG GQ G + V
Sbjct: 1100 AEAPS--------PTASPSGD---ASPPATAPYDPRVLAAGGLGQGGGGGQSSVLSGISL 1148
Query: 271 --PTTGGTGQRRGTAAAPAPTSTGTGQRRGSE 300
P T G G A PA TG Q +G+E
Sbjct: 1149 YDPRTPNAG---GKATEPA-ADTG-AQPKGAE 1175
Score = 37.7 bits (86), Expect = 0.013
Identities = 50/213 (23%), Positives = 82/213 (38%), Gaps = 44/213 (20%)
Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
++ +Q+E++ R R+L ESS+ D+ ENE+ G TG S
Sbjct: 773 IQQKQQEEEERARRLAESSKQDR--ENEE---------------GDTGNWYSSD------ 809
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRS----SSSADQQG 116
+D + + T R +T R P + G G R + S AD +
Sbjct: 810 ----EDEGGSSVTSILKTLR-QQTSSRPPASVGELSSSGLGDPRLQKGHPTGSRLADPRL 864
Query: 117 AQD----REEEAAAAPAPTSSGHRTEKRKPQQPQCRPAA-------GTGQRRGSGCSPSA 165
++D R EA+ P SG + P +P G +GSG P+
Sbjct: 865 SRDPRLTRHVEASGGSGPGDSGPSDPRLARALPTSKPEGSLHSSPVGPSSSKGSGPPPTE 924
Query: 166 DQQRAQDREEEATAAPVPTSSGH-RTEKRKRLQ 197
+++ + E+A P+ GH + R +LQ
Sbjct: 925 EEEGERALREKAVNIPLDPLPGHPLRDPRSQLQ 957
Score = 37.0 bits (84), Expect = 0.022
Identities = 48/226 (21%), Positives = 79/226 (34%), Gaps = 31/226 (13%)
Query: 48 GQRRGSGSSPSADQQGAQDREE----EAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQR 103
G+ G+ + D G +R E + + + HR KRK ++ + + + +R
Sbjct: 62 GELEDDGAEETQDTSGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKR 121
Query: 104 RGSR----SSSSADQQGAQDREEEAAAAPAPTSSGHRTEKR-----KPQQPQCRPAAGT- 153
R S+ +SSS D D + + P+ GHR + P Q P+ T
Sbjct: 122 RKSKHKRHASSSDDFSDFSDDSDFS-----PSEKGHRKYREYSPPYAPSHQQYPPSHATP 176
Query: 154 ------GQRRGSGCSPSADQQRAQ------DREEEATAAPVPTSSGHRTEKRKRLQLQCQ 201
+ D + Q D EE+ + + R+ + +
Sbjct: 177 LPKKAYSKMDSKSYGMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKEGSSR 236
Query: 202 PAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEE 247
G G+ RG R SR + G G RGSR +EE
Sbjct: 237 GRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDEE 282
Score = 34.3 bits (77), Expect = 0.14
Identities = 41/177 (23%), Positives = 67/177 (37%), Gaps = 27/177 (15%)
Query: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSS-------------PSADQQGAQDREEEAAAA 74
+ + P P+ AGG GQ G G S P+A + + + A
Sbjct: 1112 DASPPATAPYDPRVLAAGGLGQGGGGGQSSVLSGISLYDPRTPNAGGKATEPAADTGAQP 1171
Query: 75 PAPTSRGHRTEKRKPQQPQRRPAG----GTGQRRGSRSSSSADQQGAQDR-EEEAAAAPA 129
G + + + P R + TG + G+ + D+ + +R +AAAAPA
Sbjct: 1172 KGAEGNGKSSASKAKEPPFVRKSALEQPETG-KAGADGGTPTDRYNSYNRPRPKAAAAPA 1230
Query: 130 PTSSGHRTEKRKPQQ-------PQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATA 179
T++ E PQ P + GSG SP A A++ E++A +
Sbjct: 1231 ATTATPPPEGAPPQPGVHNLPVPTLFGTVKQTPKTGSG-SPFAGNSPAREGEQDAAS 1286
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 50.8 bits (120), Expect = 1e-06
Identities = 50/280 (17%), Positives = 100/280 (35%), Gaps = 5/280 (1%)
Query: 4 RQKEQDTRLRKLRESSEGDQW-LENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
+++E+ T + R++ Q E EK + R +++ Q + T R ++
Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216
Query: 63 GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREE 122
+ E R +TE+ + +Q +R A R D+ +DR +
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
Query: 123 EAAAAPAPTSSGHRTEK-RKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAP 181
+ RTE+ R+ ++ + R +R + +++R ++RE E
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERER---NRKRERERERERERERQRET 333
Query: 182 VPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRA 241
R KRKR + R G R + + R+ +R ++ R
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRD 393
Query: 242 QDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRG 281
+DR++E + + G + G+ RG
Sbjct: 394 RDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERG 433
Score = 42.0 bits (97), Expect = 7e-04
Identities = 45/254 (17%), Positives = 95/254 (37%), Gaps = 8/254 (3%)
Query: 2 KPRQKEQDTRLRKLRE-SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
K R +++D + R+ E ++ + E+ + ++ Q + T + G D
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Query: 61 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDR 120
Q ++R+ +A + R + + + + R Q R R + +DR
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
Query: 121 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAA 180
E +RK Q + R +R A+++RA +RE E
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTERER---EKQAERERASERETERDKE 261
Query: 181 PVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQR 240
R R++ + + Q T ++R R+ R+ ++R +++R
Sbjct: 262 RERERDRDRDRDRRQKERERQ----TDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 241 AQDREEEAAQPQRR 254
++RE E + ++R
Sbjct: 318 ERERERERERERQR 331
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/216 (19%), Positives = 82/216 (37%), Gaps = 14/216 (6%)
Query: 50 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRS- 108
RR GS S ++G ++A +R E+R+ ++ R +RR +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 109 --SSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSAD 166
++ +DRE+E R ++R Q+ + R G+R G D
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER---GRDRQTD 144
Query: 167 QQRAQDREEEA--------TAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSR 218
QR ++R+ +A + +R ++R+R + + + QR + R
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
Query: 219 QPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRR 254
G + R + +++R DRE + + R
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTER 240
Score = 37.0 bits (84), Expect = 0.022
Identities = 49/323 (15%), Positives = 112/323 (34%), Gaps = 18/323 (5%)
Query: 2 KPRQKEQDTRLRKLRESSEG-----DQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSS 56
K R ++++ RE G D E E+ + +++ Q R
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 57 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQG 116
++ + RE E + +E+ + ++ +R T ++R + ++
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 117 AQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEE 176
++RE++A A R ++R+ ++ + R + R ++ +DRE E
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Query: 177 ATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQR-------------RGSRSSPSRQPAGG 223
R RKR + + + QR R ++ R+
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 224 TGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTA 283
TG+ ++ +++R +DR+ + +R +++ G +
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418
Query: 284 AAPAPTSTGTGQRRGSEEMEEEG 306
+ G+ RG E +++G
Sbjct: 419 EREKDRESERGRERGREREKQKG 441
>gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]
Length = 235
Score = 50.4 bits (119), Expect = 2e-06
Identities = 45/149 (30%), Positives = 62/149 (41%), Gaps = 16/149 (10%)
Query: 163 PSADQQRAQDREEEATAAPVPTSSGHRTE-KRKRLQLQCQPAGGTGQRR----------G 211
P+ + A R T A HR +R+ +Q AG G+RR
Sbjct: 51 PAGRRPCASHRGRRITPATALLLLSHRGRAERRSMQAAAAKAGSPGRRRVGKGPPSRESW 110
Query: 212 SRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVP 271
+RS+P R P+ G R GSR S Q R + + +R G +R+ AAA
Sbjct: 111 TRSAPQRCPSQDAG-RAGSRVCRSRPQSRGGQKAAASGAKRRGVGGKEPRRQKPAAAGAK 169
Query: 272 TTGGTG----QRRGTAAAPAPTSTGTGQR 296
+ GG +RRG AAPA S G G +
Sbjct: 170 SRGGKSHKKPRRRGQKAAPAKNSGGGGNK 198
Score = 35.8 bits (81), Expect = 0.049
Identities = 50/200 (25%), Positives = 74/200 (37%), Gaps = 39/200 (19%)
Query: 94 RRPAGGT--GQRRGSRSSSSA-----DQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQ 146
+RPAG RG R + + +G +R AAA S G R + P
Sbjct: 49 QRPAGRRPCASHRGRRITPATALLLLSHRGRAERRSMQAAAAKAGSPGRRRVGKGP---- 104
Query: 147 CRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGT 206
P+ + R PS D RA R P S G Q A +
Sbjct: 105 --PSRESWTRSAPQRCPSQDAGRAGSR----VCRSRPQSRGG------------QKAAAS 146
Query: 207 GQRR---GSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRR 263
G +R G + ++PA + RG +S ++ + R ++AA + GG ++
Sbjct: 147 GAKRRGVGGKEPRRQKPAAAGAKSRGGKS-----HKKPRRRGQKAAPAKNSGGGGNKPQK 201
Query: 264 GTAAAPVPTTGGTGQ--RRG 281
AA GG G+ RRG
Sbjct: 202 AAAAGAKNRGGGGGKKPRRG 221
Score = 34.7 bits (78), Expect = 0.11
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 28/144 (19%)
Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP--APTSRGHRTEKRKPQQ 91
R Q AG G+RR PS RE +AP P+ R R +
Sbjct: 82 RRSMQAAAAKAGSPGRRRVGKGPPS--------RESWTRSAPQRCPSQDAGRAGSRVCRS 133
Query: 92 PQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSG--HRTEKRKPQ------ 143
RP GQ+ + + G + R ++ AAA A + G H+ +R+ Q
Sbjct: 134 ---RPQSRGGQKAAASGAKRRGVGGKEPRRQKPAAAGAKSRGGKSHKKPRRRGQKAAPAK 190
Query: 144 -------QPQCRPAAGTGQRRGSG 160
+PQ AAG R G G
Sbjct: 191 NSGGGGNKPQKAAAAGAKNRGGGG 214
>gi|42821110 hypothetical protein LOC340602 [Homo sapiens]
Length = 503
Score = 50.4 bits (119), Expect = 2e-06
Identities = 70/257 (27%), Positives = 91/257 (35%), Gaps = 35/257 (13%)
Query: 45 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 104
G + SP ++ Q +AA A P R E P P RP+
Sbjct: 130 GHADEHLAQTKSPGNSRRRKQPCRNQAAPAQKPPGRRLFPEPLPPSSPGFRPSSYPCS-- 187
Query: 105 GSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPS 164
G+ +SS A Q P P H +E R + + A +RR SG P
Sbjct: 188 GASTSSQATQ-------------PGPALLSHASEARPATRSRITLVASALRRRASGPGPV 234
Query: 165 ADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGT 224
TA P P HR +L + A G RRG S P PA
Sbjct: 235 I---------RGCTAQPGPAFP-HRATHLDPARLSPESAPGPA-RRGRASVPG--PA--- 278
Query: 225 GQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAA 284
RRG S+P +R +D +A R A G+ RRG +AP P R
Sbjct: 279 --RRGCDSAPGP-ARRGRDSAPVSAPRGRDSAPGSA-RRGRDSAPGPALRVRTARSDAGH 334
Query: 285 APAPTSTGTGQRRGSEE 301
T+ GTG R S +
Sbjct: 335 RSTSTTPGTGLRSRSTQ 351
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 50.4 bits (119), Expect = 2e-06
Identities = 65/254 (25%), Positives = 90/254 (35%), Gaps = 41/254 (16%)
Query: 52 GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSS 111
G+ S A D E+ +P +S E P P+ R G G R + +++
Sbjct: 45 GAAQSLPAPLTSRADPEKAVQGSPKSSSAPFEAELHLP--PKLRRLYGPGGGRLLQGAAA 102
Query: 112 ADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQR---RGSGCSPSADQQ 168
A A AAAA A ++G R E P P RP G+R G+ + +A
Sbjct: 103 AAAAAAA-----AAAAAATATAGPRGEAPPPPPPTARP----GERPDGAGAAAAAAAAAA 153
Query: 169 RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPA----GGTG------QRRGSRSSPSR 218
A D + + A V S + + PA GG G +R G P
Sbjct: 154 AAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVTHPEERLGVAGGPGS 213
Query: 219 QPAGGTGQRRGSRSSPSADQQRAQDREEEAAQ-----------------PQRRPAGGTGQ 261
PA G G + + +D EEE + P+R P TG
Sbjct: 214 APAAGGGTGTEDDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCPVAATGA 273
Query: 262 RRGTAAAPVPTTGG 275
AAA V T GG
Sbjct: 274 VAAAAAAAVATEGG 287
>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
sapiens]
Length = 2506
Score = 49.7 bits (117), Expect = 3e-06
Identities = 65/288 (22%), Positives = 99/288 (34%), Gaps = 46/288 (15%)
Query: 53 SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP---QRRPAGGTGQRRGSRSS 109
SG PS ++ + R ++ H P + Q RP G + R R S
Sbjct: 2187 SGDLPSKERDQERGRPKDRKHRQHHHHHHHHHHPPPPDKDRYAQERPDHGRARARDQRWS 2246
Query: 110 SSADQ----QGAQDREEEAAAAPAPTSSGHRTEKR----KPQQPQC-RPAAGTG---QRR 157
S + + + +PAP++SG T +R PQ P RP ++
Sbjct: 2247 RSPSEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHVSYSPVIRKA 2306
Query: 158 GSGCSPSADQQRAQDREEEATAAP----------------------VPTSSGHRTEKRKR 195
G P QQ+ Q ++++A A P P + GH + + R
Sbjct: 2307 GGSGPPQQQQQQQQQQQQQAVARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSSGRSPR 2366
Query: 196 LQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRP 255
++ + + R R +R PA G G R D +E
Sbjct: 2367 MERRVPGPARSESPRACRHGGARWPASGPHVSEGPPGPRHHGYYRGSDYDEADGPGS--- 2423
Query: 256 AGGTGQRRGTAAAPVP----TTGGTGQ--RRGTAAAPAPTSTGTGQRR 297
GG G AP P ++G TG+ R A+ PA S RR
Sbjct: 2424 GGGEEAMAGAYDAPPPVRHASSGATGRSPRTPRASGPACASPSRHGRR 2471
Score = 42.7 bits (99), Expect = 4e-04
Identities = 60/248 (24%), Positives = 86/248 (34%), Gaps = 19/248 (7%)
Query: 21 GDQWLENEKTKPLRPQQQPQCQPAGGTG--QRRGSGSSPSAD--QQGAQDREEEAAAAPA 76
G Q E+ K R + + P+G G RR S A+ ++G RE + A
Sbjct: 850 GQQRAEDFLRKQARYHDRAR-DPSGSAGLDARRPWAGSQEAELSREGPYGRESDHHAREG 908
Query: 77 ----PTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTS 132
P E+ K P RR G R SRS S + R A P
Sbjct: 909 SLEQPGFWEGEAERGKAGDPHRRHVHRQGGSRESRSGSPRTGADGEHRRHRAHRRPGEEG 968
Query: 133 SGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEK 192
+ E+R + RPA G G+ G G P ++R + R AP R E
Sbjct: 969 PEDKAERRARHREGSRPARG-GEGEGEG--PDGGERRRRHRH----GAPATYEGDARRED 1021
Query: 193 RKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQ 252
++R + + G+G S P+ Q G + P A+ + A
Sbjct: 1022 KERRHRRRKENQGSGV---PVSGPNLSTTRPIQQDLGRQDPPLAEDIDNMKNNKLATAES 1078
Query: 253 RRPAGGTG 260
P G G
Sbjct: 1079 AAPHGSLG 1086
Score = 34.3 bits (77), Expect = 0.14
Identities = 53/212 (25%), Positives = 74/212 (34%), Gaps = 18/212 (8%)
Query: 92 PQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAA 151
PQ T + R + + DQ+ Q R E+ A R RP A
Sbjct: 827 PQENRNNNTNKSRAAEPT--VDQRLGQQRAEDFLRKQARYHDRARDPSGSAGLDARRPWA 884
Query: 152 GTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 211
G+ + S P R D + P E+ K + G R
Sbjct: 885 GSQEAELSREGPYG---RESDHHAREGSLEQPGFWEGEAERGKAGDPHRRHVHRQGGSRE 941
Query: 212 SRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQR--RPA-GGTGQRRGTAAA 268
SRS R G G+ R R+ ++ +D+ E A+ + RPA GG G+ G
Sbjct: 942 SRSGSPR--TGADGEHRRHRAHRRPGEEGPEDKAERRARHREGSRPARGGEGEGEGP--- 996
Query: 269 PVPTTGGTGQRRGTAAAPAPTSTGTGQRRGSE 300
GG +RR APA T G +R E
Sbjct: 997 ----DGGERRRRHRHGAPA-TYEGDARREDKE 1023
>gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo
sapiens]
Length = 647
Score = 49.7 bits (117), Expect = 3e-06
Identities = 69/251 (27%), Positives = 88/251 (35%), Gaps = 38/251 (15%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQR 103
AGGT R A Q G + + A + +R R+ Q+P+R P Q
Sbjct: 338 AGGTWTSRFEAQRGCAHQDGQRRTRDGAGNHASEPARVWSPPPRR-QRPRRLPRASL-QE 395
Query: 104 RGSRSSSSADQQGAQDREEEAAAAP--APTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGC 161
R A GA E AA P APT R R+ Q P+ P A G SG
Sbjct: 396 EPKRRPPCARPSGAGPAREGPAAWPGGAPTPPHARPTGRR-QDPEPGPRAPRGGPASSGW 454
Query: 162 SPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPA 221
+ R D G R +R A G G R +RSSP +P
Sbjct: 455 HAGSAAGRGWD-----------PGGGSRARRRA--------ARGRGCLRSARSSPHARPL 495
Query: 222 GGTGQRRGSRSS----PSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTG 277
G + R RS+ PS D + + E Q G TTG
Sbjct: 496 GSSRSVRLLRSAAGRGPSLDSREVRVLIERGCQWWFLSRNGVDY----------TTGPRS 545
Query: 278 QRRGTAAAPAP 288
++RG A AP P
Sbjct: 546 EQRGLARAPLP 556
Score = 35.8 bits (81), Expect = 0.049
Identities = 58/209 (27%), Positives = 69/209 (33%), Gaps = 33/209 (15%)
Query: 94 RRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGT 153
RR G GQ RG R +AD A APA + E P A
Sbjct: 141 RRSCGREGQGRGGRRRRAADTLFQLGPAWPALPAPAAGRALGTDE----------PLALR 190
Query: 154 GQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ----- 208
GQ C P+A + AQ++ A AP H R L L P G G+
Sbjct: 191 GQ-----CGPAARRGCAQEQLRNAPWAP----RAHSPAGRLALGL-IAPRRGAGRAGAGA 240
Query: 209 ----RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQR----RPAGGTG 260
RRG ++P R A R AA P+ RP G G
Sbjct: 241 AACGRRGRIAAPLSGVVQKASYLRPKNLPRLLSMPSAAARPCGAALPRSGFSGRPRGRGG 300
Query: 261 QRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
G + G G RGTA PA T
Sbjct: 301 AAAGRGSRGEHPACGVGLARGTAPQPAST 329
>gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo
sapiens]
Length = 647
Score = 49.7 bits (117), Expect = 3e-06
Identities = 69/251 (27%), Positives = 88/251 (35%), Gaps = 38/251 (15%)
Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQR 103
AGGT R A Q G + + A + +R R+ Q+P+R P Q
Sbjct: 338 AGGTWTSRFEAQRGCAHQDGQRRTRDGAGNHASEPARVWSPPPRR-QRPRRLPRASL-QE 395
Query: 104 RGSRSSSSADQQGAQDREEEAAAAP--APTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGC 161
R A GA E AA P APT R R+ Q P+ P A G SG
Sbjct: 396 EPKRRPPCARPSGAGPAREGPAAWPGGAPTPPHARPTGRR-QDPEPGPRAPRGGPASSGW 454
Query: 162 SPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPA 221
+ R D G R +R A G G R +RSSP +P
Sbjct: 455 HAGSAAGRGWD-----------PGGGSRARRRA--------ARGRGCLRSARSSPHARPL 495
Query: 222 GGTGQRRGSRSS----PSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTG 277
G + R RS+ PS D + + E Q G TTG
Sbjct: 496 GSSRSVRLLRSAAGKGPSLDSREVRVLIERGCQWWFLSRNGVDY----------TTGPRS 545
Query: 278 QRRGTAAAPAP 288
++RG A AP P
Sbjct: 546 EQRGLARAPLP 556
Score = 35.8 bits (81), Expect = 0.049
Identities = 58/209 (27%), Positives = 69/209 (33%), Gaps = 33/209 (15%)
Query: 94 RRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGT 153
RR G GQ RG R +AD A APA + E P A
Sbjct: 141 RRSCGREGQGRGGRRRRAADTLFQLGPAWPALPAPAAGRALGTDE----------PLALR 190
Query: 154 GQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ----- 208
GQ C P+A + AQ++ A AP H R L L P G G+
Sbjct: 191 GQ-----CGPAARRGCAQEQLRNAPWAP----RAHSPAGRLALGL-IAPRRGAGRAGAGA 240
Query: 209 ----RRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQR----RPAGGTG 260
RRG ++P R A R AA P+ RP G G
Sbjct: 241 AACGRRGRIAAPLSGVVQKASYLRPKNLPRLLSMPSAAARPCGAALPRSGFSGRPRGRGG 300
Query: 261 QRRGTAAAPVPTTGGTGQRRGTAAAPAPT 289
G + G G RGTA PA T
Sbjct: 301 AAAGRGSRGEHPACGVGLARGTAPQPAST 329
>gi|239750916 PREDICTED: similar to hCG1803335 [Homo sapiens]
Length = 246
Score = 49.3 bits (116), Expect = 4e-06
Identities = 58/212 (27%), Positives = 75/212 (35%), Gaps = 32/212 (15%)
Query: 107 RSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQ---PQCRPAAGTGQRRGSGCSP 163
++ S Q+ A R E+ P GHR R + PQ + R + P
Sbjct: 34 KAHDSLHQRSA--RATESVPGPQSQCQGHRVSSRATESVPGPQSQFQGHRVSARATESVP 91
Query: 164 SADQQ----RAQDREEEATAAPVPTSSGHR-----TEKRKRLQLQCQPAGGTGQRRGSRS 214
Q R R E+ P GHR TE Q QCQ G R +R+
Sbjct: 92 GPQSQCQGHRVSSRATESVPGPQSQRQGHRVSARATESAPGPQSQCQ-----GHRVSARA 146
Query: 215 SPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTG 274
+ S G QR+G R S A E A PQ + G R T + P P +
Sbjct: 147 TES--VPGPQSQRQGHRVSSRA--------TESAPGPQSQFQGHRVSARATESVPGPQSQ 196
Query: 275 GTGQR---RGTAAAPAPTSTGTGQRRGSEEME 303
G R R T + P P S G R + E
Sbjct: 197 RQGHRVSSRATESVPGPQSQFQGHRVSARATE 228
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/192 (24%), Positives = 67/192 (34%), Gaps = 22/192 (11%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSR--GHRTEKRKPQQP 92
P Q QCQ + + S P + QG + + P P S+ GHR R +
Sbjct: 51 PGPQSQCQGHRVSSRATESVPGPQSQFQGHRVSARATESVPGPQSQCQGHRVSSRATES- 109
Query: 93 QRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQ---PQCRP 149
G QR+G R S+ R E+A P GHR R + PQ +
Sbjct: 110 ---VPGPQSQRQGHRVSA---------RATESAPGPQSQCQGHRVSARATESVPGPQSQR 157
Query: 150 AAGTGQRRGSGCSPSADQQ----RAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGG 205
R + +P Q R R E+ P GHR R + +
Sbjct: 158 QGHRVSSRATESAPGPQSQFQGHRVSARATESVPGPQSQRQGHRVSSRATESVPGPQSQF 217
Query: 206 TGQRRGSRSSPS 217
G R +R++ S
Sbjct: 218 QGHRVSARATES 229
Score = 46.2 bits (108), Expect = 4e-05
Identities = 59/234 (25%), Positives = 77/234 (32%), Gaps = 45/234 (19%)
Query: 67 REEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAA 126
R E+ P +GHR R + G Q +G R S+ R E+
Sbjct: 45 RATESVPGPQSQCQGHRVSSRATES----VPGPQSQFQGHRVSA---------RATESVP 91
Query: 127 APAPTSSGHRTEKRKPQQ---PQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVP 183
P GHR R + PQ QR+G R R E+ P
Sbjct: 92 GPQSQCQGHRVSSRATESVPGPQ-------SQRQG---------HRVSARATESAPGPQS 135
Query: 184 TSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQD 243
GHR R + + G R SR++ S G Q +G R S A
Sbjct: 136 QCQGHRVSARATESVPGPQSQRQGHRVSSRATES--APGPQSQFQGHRVSARA------- 186
Query: 244 REEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQR---RGTAAAPAPTSTGTG 294
E PQ + G R T + P P + G R R T + P P S G
Sbjct: 187 -TESVPGPQSQRQGHRVSSRATESVPGPQSQFQGHRVSARATESVPGPQSQFQG 239
Score = 45.1 bits (105), Expect = 8e-05
Identities = 52/183 (28%), Positives = 65/183 (35%), Gaps = 39/183 (21%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSR--GHRTEKRKPQQP 92
P Q QCQ + + S P + +QG + +AP P S+ GHR R +
Sbjct: 91 PGPQSQCQGHRVSSRATESVPGPQSQRQGHRVSARATESAPGPQSQCQGHRVSARATES- 149
Query: 93 QRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQ---PQCRP 149
G QR+G R SS R E+A P GHR R + PQ
Sbjct: 150 ---VPGPQSQRQGHRVSS---------RATESAPGPQSQFQGHRVSARATESVPGPQ--- 194
Query: 150 AAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHR-----TEKRKRLQLQCQPAG 204
QR+G R R E+ P GHR TE Q Q Q AG
Sbjct: 195 ----SQRQG---------HRVSSRATESVPGPQSQFQGHRVSARATESVPGPQSQFQGAG 241
Query: 205 GTG 207
G
Sbjct: 242 LPG 244
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.121 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,394,799
Number of Sequences: 37866
Number of extensions: 1107961
Number of successful extensions: 11855
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 268
Number of HSP's successfully gapped in prelim test: 1381
Number of HSP's that attempted gapping in prelim test: 7009
Number of HSP's gapped (non-prelim): 4679
length of query: 306
length of database: 18,247,518
effective HSP length: 102
effective length of query: 204
effective length of database: 14,385,186
effective search space: 2934577944
effective search space used: 2934577944
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.