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Search of human proteins with 116284398
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116284398 WAS/WASL interacting protein family, member 1
[Homo sapiens]
(503 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 1084 0.0
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 1084 0.0
gi|18959210 WIRE protein [Homo sapiens] 304 1e-82
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 202 8e-52
gi|160707881 formin 2 [Homo sapiens] 152 9e-37
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 151 1e-36
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 135 1e-31
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 127 2e-29
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 119 8e-27
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 119 8e-27
gi|47132519 Ras association and pleckstrin homology domains 1 is... 118 1e-26
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 116 5e-26
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 115 9e-26
gi|163965366 nascent polypeptide-associated complex alpha subuni... 115 9e-26
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 115 1e-25
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 114 2e-25
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 114 3e-25
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 111 1e-24
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 111 2e-24
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 111 2e-24
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 111 2e-24
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 111 2e-24
gi|116284392 mucin 2 precursor [Homo sapiens] 110 4e-24
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 109 7e-24
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 108 9e-24
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 104 2e-22
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 104 2e-22
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 104 2e-22
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 103 5e-22
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 103 5e-22
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 1084 bits (2804), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD 60
MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD
Sbjct: 1 MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD 60
Query: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDND 120
KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDND
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDND 120
Query: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
Query: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
Query: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP
Sbjct: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420
PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP
Sbjct: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420
Query: 421 DRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA 480
DRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA
Sbjct: 421 DRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA 480
Query: 481 RNESRSGSNRRERGAPPLPPIPR 503
RNESRSGSNRRERGAPPLPPIPR
Sbjct: 481 RNESRSGSNRRERGAPPLPPIPR 503
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 1084 bits (2804), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD 60
MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD
Sbjct: 1 MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD 60
Query: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDND 120
KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDND
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDND 120
Query: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
Query: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
Query: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP
Sbjct: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420
PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP
Sbjct: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420
Query: 421 DRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA 480
DRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA
Sbjct: 421 DRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA 480
Query: 481 RNESRSGSNRRERGAPPLPPIPR 503
RNESRSGSNRRERGAPPLPPIPR
Sbjct: 481 RNESRSGSNRRERGAPPLPPIPR 503
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 304 bits (779), Expect = 1e-82
Identities = 210/519 (40%), Positives = 251/519 (48%), Gaps = 101/519 (19%)
Query: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKK-TVTNDRSAPILD 60
P PPPP PPPPPTF ANTE+P L++ EQ GR ALL DI KG KLKK T NDRSAPIL+
Sbjct: 6 PPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSAPILE 65
Query: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDND 120
KPKG+ GG+G GG GGLFQ G+ KLR +D
Sbjct: 66 KPKGSS-----------GGYGSGGAA----------LQPKGGLFQGGVLKLRPVGAKDGS 104
Query: 121 SG-GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
+P L P R+ + +P + GR + R+ PE R + P S
Sbjct: 105 ENLAGKPALQIPSSRAAAPRP-PVSAASGRPQDDTDSSRASLPELPRMQRP-------SL 156
Query: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSP 239
PD P S+ H+ +PP P R+ + PTP P ++ A
Sbjct: 157 PDLSRPNTTSST----GMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPA---------- 202
Query: 240 LSSSSPFSNRPPLPPTPSRALDD--KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST 297
++ PLPPTP + L + PP PPPV PPP P N +
Sbjct: 203 ------YNREKPLPPTPGQRLHPGREGPPAPPPVK----------PPPSPVNIRTG---- 242
Query: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL 357
PS S APPPPP PG P PSS N+ P LPQR+ SL TP P R G
Sbjct: 243 --PSGQSLAPPPPPYRQPPGVPN-GPSSPTNESAPELPQRHNSLHRKTP---GPVR-GLA 295
Query: 358 PPPP--------SERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDS 409
PPPP S RPPPP RDPP R PPPPPV RNG +R P P P R
Sbjct: 296 PPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNG--ARDAPPPPP-PYRMHGSE 352
Query: 410 PRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCE-----DEWESRFYFHPISDLPP 464
P S +PP PP R AG PPPPPP +RNG +DS D++ES++ FHP+ D P
Sbjct: 353 PPSRGKPPPPPSRTPAGPPPPPPP--PLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPA 410
Query: 465 PEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
PE Y + YPSK +NR RGAPPLPPI R
Sbjct: 411 PEEYKHFQRIYPSK---------TNRAARGAPPLPPILR 440
Score = 212 bits (540), Expect = 6e-55
Identities = 173/484 (35%), Positives = 213/484 (44%), Gaps = 99/484 (20%)
Query: 1 MPVPPP----PAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKK-TVTNDRS 55
MP+PPP P PPPPPTF ANTE+P L++ EQ GR ALL DI KG KLKK T NDRS
Sbjct: 1 MPIPPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRS 60
Query: 56 APILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTA 115
APIL+KPKG+ GG+G GG GGLFQ G+ KLR
Sbjct: 61 APILEKPKGS-----SGGYGS----------------GGAALQPKGGLFQGGVLKLRPVG 99
Query: 116 NRD-NDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPP--- 171
+D +++ +P L P R+ + +P + GR + R+ PE R + P
Sbjct: 100 AKDGSENLAGKPALQIPSSRAAAPRP-PVSAASGRPQDDTDSSRASLPELPRMQRPSLPD 158
Query: 172 -PRPDVGSK-----PDSIPPP--------VPSTPRPIQSS---PHNRGS--PPVPG---- 208
RP+ S S PPP P TP P+ SS +NR PP PG
Sbjct: 159 LSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLH 218
Query: 209 ----GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP 264
GP P P PPP P N T G S+ P P+ P +P PS ++
Sbjct: 219 PGREGPPAPPP-VKPPPSPVNIRTGPSGQSLAPPP----PPYRQPPGVPNGPSSPTNESA 273
Query: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP--PPPSRPGPPPLP 322
P P S+HR+ P P + PP P++ PS S PPPP PPSR PP P
Sbjct: 274 PELPQ---RHNSLHRKT--PGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPP 328
Query: 323 PSSSGNDETPRLPQRNLSLSSSTPPLPSPGR-SGPLPPPPSERPPPPVRDPPGRSGPLPP 381
P N + PP P P R G PP + PPPP R P +GP PP
Sbjct: 329 PPVIRNG------------ARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTP---AGPPPP 373
Query: 382 PPPVSRNG---STSRALPATPQLPSRSGVDSPRSGPRP----------PLPPDRPSAGAP 428
PPP RNG S + S+ P P P +R + GAP
Sbjct: 374 PPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHFQRIYPSKTNRAARGAP 433
Query: 429 PPPP 432
P PP
Sbjct: 434 PLPP 437
Score = 57.0 bits (136), Expect = 4e-08
Identities = 57/218 (26%), Positives = 80/218 (36%), Gaps = 31/218 (14%)
Query: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPP 366
P PPPPP PGPPP P N E P+L + + G ++R
Sbjct: 2 PIPPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSA 61
Query: 367 PPVRDPPGRSG-------PLPPP------------PPVSRNGSTSRALPATPQLPSRSGV 407
P + P G SG L P P +++GS + A Q+PS
Sbjct: 62 PILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPS---- 117
Query: 408 DSPRSGPRPPL------PPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISD 461
S + PRPP+ P D + P R D + S H S
Sbjct: 118 -SRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHS-SS 175
Query: 462 LPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLP 499
PPP P + + P+ L + S++ + RE+ PP P
Sbjct: 176 APPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTP 213
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 202 bits (513), Expect = 8e-52
Identities = 168/515 (32%), Positives = 223/515 (43%), Gaps = 103/515 (20%)
Query: 1 MPVPPPPA---PPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKK-TVTNDRSA 56
+P PPPP PPPPP+ +T+ +L + + GR+ALL+DI +G +L+K T NDRSA
Sbjct: 11 LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSA 70
Query: 57 PILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTAN 116
P ++ KG GGG + G PP LG LF G P LR
Sbjct: 71 PQIESSKGTNK----------------EGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQ 114
Query: 117 RDNDSG------GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH---RSGPPEPQRN 167
RD G GSR P P T + P PP+ P R S H R+ PP P
Sbjct: 115 RDVAGGKTGQGPGSRAP-SPRLPNKTISGPLIPPASP-RLGNTSEAHGAARTAPPRPNVP 172
Query: 168 RMPPPRPDVGSKPDSIPPPVPS-----TPRPIQSSPHNRG-----SPPVPGGPRQPSPGP 217
PPP P P +PPP+PS TP P +G +PPVP P P P P
Sbjct: 173 APPPPTPP--PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP--PPPPP 228
Query: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP--PPVGNRP 275
PPP P PL +S S++ P L PPP P PP G P
Sbjct: 229 PPPPTP--------------PPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCG-YP 273
Query: 276 SIHREAVPPPPPQN-NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
+ +A P P Q+ +PP P P P +S +P P PPLP +S ++ P L
Sbjct: 274 GL--KAEPASPAQDAQEPPAPPPPLPPYASCSPRASLP-----APPLPGVNSSSETPPPL 326
Query: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGP-----LPPPPPVSRNG 389
P + S S PP + ++ P PP P P + GR G PPP P +R+
Sbjct: 327 PPK--SPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
Query: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449
+T +L S+S + + P P +RNG D+
Sbjct: 385 TT--------ELSSKS----------------QQATAWTPTQQPGGQLRNG--SLHIIDD 418
Query: 450 WESRFYFHPISDLPPPEPYVQTTKSYPSKLARNES 484
+ES+F FH + D PPP+ Y K YPSK+ R+ +
Sbjct: 419 FESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRT 453
Score = 102 bits (255), Expect = 6e-22
Identities = 122/423 (28%), Positives = 153/423 (36%), Gaps = 106/423 (25%)
Query: 140 PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP- 198
P PP P P+P P G P P PP D S + P + IQ
Sbjct: 2 PVPPPPPP---PLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
Query: 199 -------HNRGSPPVP--------GGPRQPSPGPTPPP---------FP-----GNRGTA 229
++R +P + GG + G + PP FP G R A
Sbjct: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118
Query: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP-PPPPPPVGNRPSIHREAVPPPPPQ 288
GG Q P +R P P P++ + PP P +GN H A PP
Sbjct: 119 --GGKTGQGP-------GSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP-- 167
Query: 289 NNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP--SSSGNDETPRL----PQRNLSLS 342
+P VP APPPP PP P PPPLPP SS +TP + P +L
Sbjct: 168 --RPNVP----------APPPPTPP--PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
Query: 343 SSTPPLPSPGRSGPLPPPPSERPPPPV----------RDPPGRSGPLPPP----PPVSRN 388
PP+P P PPPP+ P PP + P P+PPP PP
Sbjct: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
Query: 389 G-STSRALPA---------TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIR 438
G A PA P LP + S P PPLP S+ PPP PP +
Sbjct: 274 GLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSP-- 331
Query: 439 NGFQDSPCEDEWESRFYFHPISDLP-PPEPYVQTTKSYPSKLARNESRSGSNRRERGAPP 497
FQ P + ++ LP PP P S P + R G+ + PP
Sbjct: 332 -SFQAPPQKAGAQA---------LPAPPAP----PGSQPFLQKKRHGRPGAGGGKLNPPP 377
Query: 498 LPP 500
PP
Sbjct: 378 APP 380
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 152 bits (383), Expect = 9e-37
Identities = 141/451 (31%), Positives = 172/451 (38%), Gaps = 94/451 (20%)
Query: 88 GGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF------ 141
G G G P + FQ S+A +++ + S PPL P S+S+ P
Sbjct: 821 GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL--PCTESSSSMPGLGMVPP 878
Query: 142 SPPSGPGRF--PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTP-RPIQSSP 198
PP PG +PS PP +PPP P + PPP+P P+
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL---- 934
Query: 199 HNRGSPPVPGG---PRQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPL 252
PP+PG P P PG P PPP PG PL P + PP
Sbjct: 935 -----PPLPGAGIPPPPPLPGAAIPPPPPLPG-----------AGIPLPPPLPGAGIPPP 978
Query: 253 PPTPSRALDDKPPPPPPP---VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP 309
PP P + PPPPP P + P + +PPPPP P P P A PPP
Sbjct: 979 PPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035
Query: 310 ------PPPPSRPG---PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
PPPP PG PPP P +G P LP + PPLP G P P P
Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLP 1092
Query: 361 PSERPPPP------VRDPPGRSGP-LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
+ PPPP + PP G +PPPPP+ G +P P LP +G+ P
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG-----IPPPPPLPG-AGIPPPPPL 1146
Query: 414 PRP--PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQT 471
PR P PP P AG PPPPP P + +PPP P
Sbjct: 1147 PRVGIPPPPPLPGAGIPPPPP------------------------LPGAGIPPPPPLPGV 1182
Query: 472 TKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
P L G PP PP+P
Sbjct: 1183 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213
Score = 150 bits (380), Expect = 2e-36
Identities = 129/377 (34%), Positives = 151/377 (40%), Gaps = 62/377 (16%)
Query: 97 PPGLGGLFQAGMPKLRSTANRDND--SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS 154
PP L G+ +P L STA G P PP P P G G P+P
Sbjct: 880 PPPLPGMT---VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936
Query: 155 -PGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRG---SPPVPGG- 209
PG PP P PP P + +PPP+P P G PP+PG
Sbjct: 937 LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 996
Query: 210 --PRQPSPG---PTPPPFPGNR---GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD 261
P P PG P PPP PG L G I P P + PP PP P +
Sbjct: 997 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIP 1053
Query: 262 DKPP------PPPPPVGNR-----PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP- 309
PP PPPPP+ P + +PPPPP P P P PPP
Sbjct: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113
Query: 310 -----PPPPSRPG---PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
PPPP PG PPP P +G P LP+ + PPLP G P P P
Sbjct: 1114 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIP---PPPPLPGAGIPPPPPLPG 1170
Query: 362 SERPPPP------VRDPPGRSGP-LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414
+ PPPP + PP G +PPPPP+ G +P P LP G+ P + P
Sbjct: 1171 AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAG-----IPPPPPLP---GMGIPPA-P 1221
Query: 415 RPPLPPDRPSAGAPPPP 431
PPLPP P G PPPP
Sbjct: 1222 APPLPP--PGTGIPPPP 1236
Score = 144 bits (363), Expect = 2e-34
Identities = 131/411 (31%), Positives = 154/411 (37%), Gaps = 110/411 (26%)
Query: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRF--------PVPSPGHRSGPPEPQRNRMPPP 172
+G +P PP ST + S F P P P S P +PPP
Sbjct: 820 AGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP 879
Query: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG---PTPPPFPGNRGTA 229
P + P P +PST P P +G+ +P P P PG P PPP PG
Sbjct: 880 PPPL---PGMTVPTLPSTAIP--QPPPLQGTEMLPPPP-PPLPGAGIPPPPPLPG----- 928
Query: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP---VGNRPSIHREAVPPPP 286
G + PL P + PP PP P A+ PPPPP P + P + +PPPP
Sbjct: 929 --AGILPLPPL----PGAGIPPPPPLPGAAI---PPPPPLPGAGIPLPPPLPGAGIPPPP 979
Query: 287 PQNNKPPVPSTPRPSASSQAPPP------PPPPSRPG---PPPLPPSSSGNDETPRLPQR 337
P P P P A PPP PPPP PG PPP P +G P LP
Sbjct: 980 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1039
Query: 338 NLSLSSSTPPLPSPGRSGPLPPP-PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
+ PP P PG P PPP P PPP PP +PPPPP+ G +P
Sbjct: 1040 GIP-----PPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAG-----IP 1086
Query: 397 ATPQLPSRSGVDSPRSGPRP----PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
P LP G P P P P PP P AG PPPPP
Sbjct: 1087 PPPPLP---GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL------------------- 1124
Query: 453 RFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
P + +PPP P G PP PP+PR
Sbjct: 1125 -----PGAGIPPPPPLPGA----------------------GIPPPPPLPR 1148
Score = 128 bits (322), Expect = 1e-29
Identities = 113/340 (33%), Positives = 137/340 (40%), Gaps = 57/340 (16%)
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPSG-PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
G PP P G P P +G P P+P G PP P +PPP P G+
Sbjct: 972 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGA-- 1028
Query: 181 DSIPPPVPSTPRPIQSSPHNRGS-----PPVPGG---PRQPSPG---PTPPPFPGNR--- 226
IPPP P I P G+ PP+PG P P PG P PPP PG
Sbjct: 1029 -GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
Query: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP------PPPPPVGNR-----P 275
L G I P P PP PP P + PP PPPPP+ P
Sbjct: 1088 PPPLPGAGIPPPP---PLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1144
Query: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
+ R +PPPPP P P P A PPPPP P PPP P G P LP
Sbjct: 1145 PLPRVGIPPPPPLPGAGIPPPPPLPGAG--IPPPPPLPGVGIPPPPPLPGVGIPPPPPLP 1202
Query: 336 QRNLSLSSSTPPLPS----PGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGST 391
+ PPLP P + PLPPP + PPPP+ P+ PP + + GS+
Sbjct: 1203 GAGI---PPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLL-------PVSGPPLLPQVGSS 1252
Query: 392 SRALPAT-----PQLPS---RSGVDSPRSGPRPPLPPDRP 423
+ P P LPS G++ + + P+ P RP
Sbjct: 1253 TLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
Score = 66.2 bits (160), Expect = 6e-11
Identities = 86/326 (26%), Positives = 108/326 (33%), Gaps = 88/326 (26%)
Query: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
SI+ SP + LPP +D P PP P G E+ P +
Sbjct: 743 SIQTSPTEEGGVLT----LPP-----VDGLPGRPPCPPG------AESGPQTKFCSEISL 787
Query: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST-------- 345
+ S R S + P S+P PPP S+G + P ++S T
Sbjct: 788 IVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSS 847
Query: 346 -----------PPLPSPGRS------GPLPPPPSERP--------------PPPVR---- 370
PPLP S G +PPPP P PPP++
Sbjct: 848 AFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEM 907
Query: 371 ----DPPGRSGPLPPPPPVSRNG------STSRALPATPQLPSRSGVDSPRSGPRP---- 416
PP +PPPPP+ G +P P LP G P P P
Sbjct: 908 LPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP---GAAIPPPPPLPGAGI 964
Query: 417 PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYP 476
PLPP P AG PPPPP + G P P + +PPP P P
Sbjct: 965 PLPPPLPGAGIPPPPPLPGA---GIPPPPP----------LPGAGIPPPPPLPGAGIPPP 1011
Query: 477 SKLARNESRSGSNRRERGAPPLPPIP 502
L G PP PP+P
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLP 1037
Score = 36.6 bits (83), Expect = 0.055
Identities = 98/429 (22%), Positives = 131/429 (30%), Gaps = 99/429 (23%)
Query: 68 GGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP 127
G GG G G GGGGGGGGG S + + ++R ++ +GGSR
Sbjct: 38 GSGGKKALGKHGKGGGGGGGGGESGKKKSKSDSRASVFSNL-RIRKNLSKGKGAGGSRED 96
Query: 128 LLPPGGRSTS-----------------------------AKPF--SPPSGPGRFPVPSPG 156
+L T A PF + P GPG P+
Sbjct: 97 VLDSQALQTGELDSAHSLLTKTPDLSLSADEAGLSDTECADPFEVTGPGGPG----PAEA 152
Query: 157 HRSGPP-----EPQRNRMPPPRPDVGSKPD---------------SIPPPV---PSTPRP 193
G P E R GS D I + +
Sbjct: 153 RVGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQ 212
Query: 194 IQSSPHNRGSPPVPGGPRQPSPGPTP-PPFPGN--------RGTALGGGSIRQSPLSSSS 244
+Q + G +P+ PT P PG G + G G SP +
Sbjct: 213 LQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSP-DTEQ 271
Query: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP-PPPPQNNKPPVPSTPRPSAS 303
S LP S A + + P PP G P ++P P + P + P P A
Sbjct: 272 ALSALSDLP--ESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAG 329
Query: 304 SQAPPPPPPPSRPGP----------PPLPPSSSGNDETPRL----PQRNLSLSSSTPPLP 349
P G P S G + P + PQR P
Sbjct: 330 PGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
Query: 350 SPGRSGPLP--PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407
+ LP P PS+R P PL P + +T+R L + PS+S
Sbjct: 390 DAPAAASLPGSPAPSQRCFKPY--------PLITPCYIK---TTTRQLSSPNHSPSQSPN 438
Query: 408 DSPRSGPRP 416
SPR RP
Sbjct: 439 QSPRIKRRP 447
Score = 31.6 bits (70), Expect = 1.8
Identities = 60/251 (23%), Positives = 80/251 (31%), Gaps = 49/251 (19%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-PSPGHRSGPPEPQRN-------------- 167
G+ P PP S F G RF + PS G P P
Sbjct: 228 GAEEPAAPPTAVSPQPGAFL---GLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLA 284
Query: 168 ---RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224
R P P G P S P +P+ + SP + P GP + + G
Sbjct: 285 AEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAG-------- 336
Query: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284
G G + F + P P A + P +G P EA P
Sbjct: 337 --APVRGAGDTDEE--GEEDAFEDAPRGSPGEEWA-PEVGEDAPQRLGEEP--EEEAQGP 389
Query: 285 PPPQNNKPPVPSTPRPSASSQAPPPPPPP-------SRPGPPPLPPSSSGNDETPRL--- 334
P +P +P PS P P P + P PS S N ++PR+
Sbjct: 390 DAPA--AASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPN-QSPRIKRR 446
Query: 335 PQRNLSLSSST 345
P+ +LS S T
Sbjct: 447 PEPSLSRGSRT 457
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 151 bits (382), Expect = 1e-36
Identities = 134/425 (31%), Positives = 167/425 (39%), Gaps = 53/425 (12%)
Query: 35 ALLSDISKGKKLKKTVTNDRSAPIL-DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFG 93
ALL+ +S + L + V+ + S ++ P+GA GG G G G G
Sbjct: 9 ALLA-LSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQ 67
Query: 94 GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGR--------STSAKPFSPPS 145
GPP G Q P+ GG++P PP G+ S P SPP
Sbjct: 68 PQGPPPPPGKPQGPPPQ-----------GGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 116
Query: 146 GPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPP 205
P P GPP P PP P G+KP PPP P Q +R S
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRS 175
Query: 206 VPGGPRQPSP-------GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPS- 257
PG P+ P P GP PPP +G GG+ Q P P PP S
Sbjct: 176 PPGKPQGPPPQGGNQPQGPPPPP-GKPQGPPPQGGNKPQGPPPPGKP-QGPPPQGDNKSQ 233
Query: 258 --RALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
R+ KP PPP GN+P PPPPP P P P ++ PPPP
Sbjct: 234 SARSPPGKPQGPPPQGGNQPQ-----GPPPPPGK-----PQGPPPQGGNKPQGPPPPGKP 283
Query: 316 PGPPPLPPSSSGNDET-PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPG 374
GPPP S S + + P PQ + P P P P PPP P PPG
Sbjct: 284 QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343
Query: 375 RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP----PLPPDRPSAGAP-- 428
+ P PPP ++R+ P PQ P + ++P+ P P P P P AG P
Sbjct: 344 K--PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 401
Query: 429 PPPPP 433
PP PP
Sbjct: 402 PPRPP 406
Score = 142 bits (357), Expect = 9e-34
Identities = 123/381 (32%), Positives = 149/381 (39%), Gaps = 61/381 (16%)
Query: 103 LFQAGMPKLRSTANRDNDSGGSRPPLL--------PPGGRSTSAKPFSPPSGPGR--FPV 152
L + L S N + D P L PP G + KP PPS PG+ P
Sbjct: 5 LLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGN---KPQGPPSPPGKPQGPP 61
Query: 153 PSPGHR-SGPPEPQRNRMPPPRPDVGSKPDSIPPP-VPSTPRP------IQSSPHNRGSP 204
P G++ GPP P PP P G+KP PPP P P P SP +
Sbjct: 62 PQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 120
Query: 205 PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP-------TPS 257
P P G QP P PP P +G GG+ Q P P +P PP S
Sbjct: 121 PPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGP-----PPPGKPQGPPPQGDNKSRSS 173
Query: 258 RALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG 317
R+ KP PPP GN+P PPPPP P P P ++ PPPP G
Sbjct: 174 RSPPGKPQGPPPQGGNQPQ-----GPPPPPGK-----PQGPPPQGGNKPQGPPPPGKPQG 223
Query: 318 PPPLPPSSSGNDET-PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS 376
PPP + S + + P PQ + P P P P PPP P PPG+
Sbjct: 224 PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK- 282
Query: 377 GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP-------SAGAPP 429
P PPP +SR+ P PQ P G + P+ P PP P P G PP
Sbjct: 283 -PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 341
Query: 430 P-----PPPSTSIRNGFQDSP 445
P PPP ++ SP
Sbjct: 342 PGKPQGPPPQGGSKSRSARSP 362
Score = 124 bits (312), Expect = 2e-28
Identities = 119/390 (30%), Positives = 151/390 (38%), Gaps = 58/390 (14%)
Query: 4 PPPPAPP--PPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
PPPP P PPP P K + +G K + + RS P K
Sbjct: 72 PPPPGKPQGPPPQGGNKPQGPPPPGKPQ--------GPPPQGDKSR----SPRSPP--GK 117
Query: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121
P+G GG G G G G GPP G G P +R + S
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPPQGDNKSRSSRS 175
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHR-SGPPEPQRNRMPPPRPDVGSKP 180
+P PP G + P PP G + P P G++ GPP P + + PPP+ D S+
Sbjct: 176 PPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQS 234
Query: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP----GPTPPPFPGN-RGTALGGGSI 235
PP P P P Q +G PP PG P+ P P P PP PG +G GGS
Sbjct: 235 ARSPPGKPQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 293
Query: 236 RQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVP 295
+S SR+ KP PPP GN+P PPPPP P
Sbjct: 294 SRS------------------SRSPPGKPQGPPPQGGNQPQ-----GPPPPPGK-----P 325
Query: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET----PRLPQRNLSLSSSTPPLPSP 351
P P ++ PPPP GPPP S S + + P+ P + + PP P+
Sbjct: 326 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAG 385
Query: 352 GRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
G PP+ +P P R P G PP
Sbjct: 386 GNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 135 bits (339), Expect = 1e-31
Identities = 114/362 (31%), Positives = 138/362 (38%), Gaps = 68/362 (18%)
Query: 103 LFQAGMPKLRSTANRDNDSGGSRPPLL---------PPGGRSTSAKPFSPPSGPGRFPVP 153
L + L S N + D P L P GG P PP G + P P
Sbjct: 5 LLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPP--PPPGKPQGPPP 62
Query: 154 SPGHR-SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ 212
G++ GPP P + + PPP+ D P S PP P P P Q +G PP PG P+
Sbjct: 63 QGGNKPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPP-QGGNQPQGPPPPPGKPQG 120
Query: 213 PSPG----PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP 268
P P P PP PG G +SP S PP KP PP
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS-----------PP-------GKPQGPP 162
Query: 269 PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRP-GPPPLPPSSSG 327
P GN+P PPPPP KP P P + P PPPP +P GPPP S
Sbjct: 163 PQGGNQPQ-----GPPPPP--GKPQGP----PPQGGKKPQGPPPPGKPQGPPPQGDKSRS 211
Query: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387
+ P PQ + P P P P PPP P PPG+ P PP
Sbjct: 212 SQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPAQGGS 269
Query: 388 NGSTSRALPATPQLPSRSGVDSPRSGPRPPL-----------------PPDRPSAGAPPP 430
++R+ P PQ P + ++P+ GP PP PP P G P
Sbjct: 270 KSQSARSPPGKPQGPPQQEGNNPQ-GPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328
Query: 431 PP 432
PP
Sbjct: 329 PP 330
Score = 115 bits (288), Expect = 9e-26
Identities = 107/345 (31%), Positives = 139/345 (40%), Gaps = 35/345 (10%)
Query: 35 ALLSDISKGKKLKKTVTNDRSAPIL-DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFG 93
ALL+ +S + L + V+ + S ++ P+G GG G G G G
Sbjct: 9 ALLA-LSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK 67
Query: 94 GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP 153
GPP G + P + +R S +P PP G + P PP G + P P
Sbjct: 68 PQGPPPPG---KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPP 123
Query: 154 SPGHR-SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ 212
G+R GPP P + + PPP+ D P S PP P P P Q +G PP PG P+
Sbjct: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPP-QGGNQPQGPPPPPGKPQG 181
Query: 213 PSPG----PTPPPFPGN-RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267
P P P PP PG +G G R SS SP PP PPPP
Sbjct: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDKSR----SSQSPPGKPQGPPPQGGNQPQGPPPPP 237
Query: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP--PPPPPSRPG--PPPLPP 323
P G P + PPPP + P S S+++PP P PP + G P PP
Sbjct: 238 GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 297
Query: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
+ GN + P+ P P+ GP PP RP P
Sbjct: 298 PAGGNPQQPQAP-------------PAGQPQGPPRPPQGGRPSRP 329
Score = 108 bits (269), Expect = 1e-23
Identities = 87/271 (32%), Positives = 100/271 (36%), Gaps = 61/271 (22%)
Query: 172 PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALG 231
P P G+KP PPP P P+ G PP G Q P P P P +G
Sbjct: 39 PSPQGGNKPQG-PPPPPGKPQ---------GPPPQGGNKPQGPPPPGKPQGPPPQGDK-- 86
Query: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291
S P PP KP PPP GN+P PPPPP
Sbjct: 87 ---------------SRSPRSPP-------GKPQGPPPQGGNQPQ-----GPPPPPGK-- 117
Query: 292 PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP 351
P P P ++ PPPP GPPP S P PQ PP
Sbjct: 118 ---PQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ-------GPPPQGGN 167
Query: 352 GRSGPLPPPPSERPPPPVRDPPGRSGPLPP-----PPPVSRNGSTSRALPATPQLPSRSG 406
GP PPPP + PP + GP PP PPP +S++ P PQ P G
Sbjct: 168 QPQGP-PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226
Query: 407 VDSPRSGPRPPLPPD--RPSAGAPP--PPPP 433
+ P+ P PP P P G P PPPP
Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257
Score = 103 bits (257), Expect = 4e-22
Identities = 82/247 (33%), Positives = 91/247 (36%), Gaps = 37/247 (14%)
Query: 96 GPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGR--------STSAKPFSPPSGP 147
GPP GG G P GG+RP PP G+ S P SPP P
Sbjct: 99 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 158
Query: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPP-VPSTPRP------IQSSPHN 200
P GPP P PP P G KP PPP P P P SP
Sbjct: 159 QGPPPQGGNQPQGPPPPPGKPQGPP-PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217
Query: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTP---- 256
+ P P G QP P PP P +G GG+ Q P P +P PP
Sbjct: 218 KPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGP-----PPPGKPQGPPAQGGSK 270
Query: 257 ---SRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313
+R+ KP PP GN P PPPP P P P P+ Q PP PP
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQ------GPPPPAGGNPQQPQAP-PAGQPQGPPRPPQG 323
Query: 314 SRPGPPP 320
RP PP
Sbjct: 324 GRPSRPP 330
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/220 (27%), Positives = 76/220 (34%), Gaps = 50/220 (22%)
Query: 295 PSTPRPSASSQAPPPPPPPSRP-GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353
P P P ++ PPPPP +P GPPP + P PQ PP R
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ-------GPPPQGDKSR 88
Query: 354 SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
S PP + PPP G + P PPPP P PQ P G + P+ G
Sbjct: 89 SPRSPPGKPQGPPPQ-----GGNQPQGPPPP-----------PGKPQGPPPQGGNRPQ-G 131
Query: 414 PRPPLPPDRP--------SAGAPP-----PPPPSTSIRNGFQDSPCEDEWESRFYFHPIS 460
P PP P P S +PP PPP + G P + +
Sbjct: 132 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG---------- 181
Query: 461 DLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPP 500
PPP+ + P + G R +PP P
Sbjct: 182 --PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219
Score = 47.4 bits (111), Expect = 3e-05
Identities = 40/116 (34%), Positives = 46/116 (39%), Gaps = 20/116 (17%)
Query: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSP--GRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
SS+ N + + SL + P PSP G PPPP +P P P G + P P
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP--PPQGGNKPQGP 71
Query: 382 PPPVSRNGSTSRALPATPQLPSRSG--VDSPRSGPRPPLPPDRPSAGAP--PPPPP 433
PPP PQ P G SPRS P P P P PPPPP
Sbjct: 72 PPP------------GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 127 bits (319), Expect = 2e-29
Identities = 105/312 (33%), Positives = 122/312 (39%), Gaps = 58/312 (18%)
Query: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPS 189
P GG P P GR P + PP P + PPP+ G PPP P
Sbjct: 41 PQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQ---GGNQSQGPPPRPG 97
Query: 190 TP--RPIQSSPHNRGSPPVPGGPRQPSP-----GPTPPPFPGN-RGTALGGGSIRQSPLS 241
P +P Q ++G PP PG P P P PPP PG G GG+ Q P
Sbjct: 98 KPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP-- 155
Query: 242 SSSPFSNRPPLPPTPSRALDDKPPPPP-PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
P +P PP PPP P P G P ++ PPP +P P P P
Sbjct: 156 --PPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPP----RPGKPEGPPP 209
Query: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
+Q+ PPP RPG P PPS GN PQ P P PG+ P PP
Sbjct: 210 QGGNQSQGPPP---RPGKPEGPPSQGGNK-----PQG---------PPPHPGK--PQGPP 250
Query: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420
P E P PPGR P PPPP G+ + LP P P+ P PP
Sbjct: 251 PQEGNKPQRPPPPGR--PQGPPPP---GGNPQQPLPP------------PAGKPQGPPPP 293
Query: 421 DRPSAGAPPPPP 432
P G P PP
Sbjct: 294 --PQGGRPHRPP 303
Score = 111 bits (278), Expect = 1e-24
Identities = 110/362 (30%), Positives = 133/362 (36%), Gaps = 81/362 (22%)
Query: 35 ALLSDISKGKKLKKTVTNDRSAPILD-KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFG 93
ALL+ +S + L + V+ + S ++ KP+G GG G G G
Sbjct: 9 ALLA-LSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQ 67
Query: 94 GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP 153
GPP + G P+ PP P GG + P P G+ P
Sbjct: 68 SQGPPP-----RPGKPE--------------GPP--PQGGNQSQGPPPRPGKPEGQPPQG 106
Query: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPR--PIQSSPHNRGSPPVPGGPR 211
+ PP P + PPP+ G PPP P P P Q ++G PP PG P
Sbjct: 107 GNQSQGPPPRPGKPEGPPPQ---GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 163
Query: 212 QPSP-----GPTPPPFPGN-RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265
P P PPP PG G GG+ Q P PP P KP
Sbjct: 164 GPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGP-------------PPRPG-----KPE 205
Query: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325
PPP GN+ PPP+ KP P PS P PPP PG P PP
Sbjct: 206 GPPPQGGNQSQ-------GPPPRPGKPEGP----PSQGGNKPQGPPP--HPGKPQGPPPQ 252
Query: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
GN PQR P PGR PPPP P P+ P G+ PPPP
Sbjct: 253 EGNK-----PQRP----------PPPGRPQG-PPPPGGNPQQPLPPPAGKPQGPPPPPQG 296
Query: 386 SR 387
R
Sbjct: 297 GR 298
Score = 51.2 bits (121), Expect = 2e-06
Identities = 42/136 (30%), Positives = 49/136 (36%), Gaps = 24/136 (17%)
Query: 96 GPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPG---RFPV 152
GPP GG G P GG++ PP KP PPS G + P
Sbjct: 185 GPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP----RPGKPEGPPSQGGNKPQGPP 240
Query: 153 PSPGHRSGPPEPQRN---RMPPPR------PDVGSKPDSIPPPVPSTPRPIQSSPHNRGS 203
P PG GPP + N R PPP P G+ +PPP P
Sbjct: 241 PHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPA--------GKPQGPPP 292
Query: 204 PPVPGGPRQPSPGPTP 219
PP G P +P G P
Sbjct: 293 PPQGGRPHRPPQGQPP 308
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 119 bits (297), Expect = 8e-27
Identities = 110/358 (30%), Positives = 144/358 (40%), Gaps = 61/358 (17%)
Query: 115 ANRDNDSGGSRPPLLPPGGRS--TSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPP 172
A R +GG L P RS +SA P S P+ G P R P P P P
Sbjct: 215 ARRRPSAGGG---LQRPASRSLSSSATPLSSPARSG------PSARGTPRAPAHPSQPKP 265
Query: 173 RPDVGSKPDSIPPPVPSTPR---PIQSSPHNRGSPPVPGGPRQP---SPGPTPPPFPGNR 226
+ +P + PP P+ SSP SP P P P P+PP P ++
Sbjct: 266 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325
Query: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPP 286
T S+ L ++ F PPL P + PPP PP P + PP
Sbjct: 326 ATT----SLGSPTLQATHSFLPSPPLSPLAT------PPPQAPPALALPPLQAPPSPPAS 375
Query: 287 PQNNKPPVPSTPRPSASS----QAP--PPPPPP-----SRPGPPPLPPSSSGNDETPRLP 335
P + PS P+A + QAP PPP PP S P PP+ PS++ + P
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP-- 433
Query: 336 QRNLSLSSSTPPL---PSPGRSGPLPPP--PSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
S + PPL PSP S P+ P P + PPP+ PP + PP P +
Sbjct: 434 ------SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487
Query: 391 TSRALPATPQ--------LPSRSGVDSPRSGPRPPLPP--DRPSAGAPPPPPPSTSIR 438
+ALP+ P PS S SP + P P PP P PP PP S +++
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 545
Score = 102 bits (255), Expect = 6e-22
Identities = 114/386 (29%), Positives = 138/386 (35%), Gaps = 51/386 (13%)
Query: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGS--KPDSI 183
P L P ++ + P SPP P P P + Q PPP P V + P +
Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418
Query: 184 PPPVPSTPRPIQSSPHNRGSPPV---PGGPRQP--SPGPTPPPFPGNRGTALGGGSIRQS 238
PP PS P Q+ P + +PP+ P P P SP TPPP Q+
Sbjct: 419 PPVSPSATPPSQAPP-SLAAPPLQVPPSPPASPPMSPSATPPP---------------QA 462
Query: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP 298
P PPL P + KPPP PP P + PP P PS
Sbjct: 463 P----------PPLAAPPLQLA--KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510
Query: 299 RPSASSQAPPPPPPPSRPGP----PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354
P + PPP PP P PP PP+S R P S S P L
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 570
Query: 355 GPLPPPPSERPPPPVRDP--PGRSGPLPPPPPVSR--NGSTSRALPATPQLPSRSGVDSP 410
GP PPPPS P + P G S P R + A+P + P
Sbjct: 571 GP-PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 629
Query: 411 RSGPRPPLPP--DRPSAGAPPPPPPSTSIRNGFQDSPC---EDEWESRFYFHPISDLPPP 465
+ R P PP R + GAP P PP+T G D C E E P + P P
Sbjct: 630 AAWSRGPAPPLAFRGAPGAPLPWPPATG--PGSADGLCTIYETEGPESATPAPGALDPGP 687
Query: 466 EPYVQTTKSYPSKLARNESRSGSNRR 491
P K+ A SRS R
Sbjct: 688 SPGTSGGKAAAGAGAGASSRSPKQAR 713
Score = 100 bits (249), Expect = 3e-21
Identities = 115/389 (29%), Positives = 144/389 (37%), Gaps = 72/389 (18%)
Query: 101 GGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160
GG+ A +P+ +A R + SRPP G R+ AK SP PV SPG SG
Sbjct: 63 GGIGGATIPE---SAPRAGPTRTSRPPASGRGERAPPAKNTSPG------PVSSPGRASG 113
Query: 161 PPEPQ------------------RNRMPPPRP--DVGSKPDSIPPPVPSTPRPIQSSPHN 200
P + P R G++ D+ P P TP P + +
Sbjct: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT-SGPTPGTPSPAMAR-RS 171
Query: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP-----LPPT 255
R + G PR P P+ P P G S + + SP + R P L
Sbjct: 172 RAAGTEVGLPR---PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228
Query: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP--------PVPSTPRPSAS---- 303
SR+L P P + PS P P KP P + PR A+
Sbjct: 229 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288
Query: 304 --SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP-------LPSPGRS 354
S +P P PS P P PPS P P + S +P LPSP S
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348
Query: 355 GPLPPPPSERPP----PPVRDPPG--RSGPLPP---PPPVSRNGSTSRALPATPQLPSRS 405
PL PP + PP PP++ PP S PL P P P + N L A P
Sbjct: 349 -PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407
Query: 406 GVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
V +P S P PP PSA P PPS
Sbjct: 408 PVQAPFSPPAS--PPVSPSATPPSQAPPS 434
Score = 77.0 bits (188), Expect = 4e-14
Identities = 116/426 (27%), Positives = 148/426 (34%), Gaps = 139/426 (32%)
Query: 210 PRQP-SPGPTPPPFP-----------------GNRGTALGGGSIRQSPLSSSSPFSNRPP 251
PR P SP P PP P R +GG +I +S + ++RPP
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86
Query: 252 -------LPP----------TPSRALDDKPPPPPPPVGNRPSIH-------------REA 281
PP +P RA P P G R S R A
Sbjct: 87 ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 146
Query: 282 VPPPPPQNNKPPVPSTPRPSASSQAP--------PPPPPPSRPGPP-------------- 319
+ ++ P P TP P+ + ++ P P P +RP PP
Sbjct: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 206
Query: 320 ----PLP-----PSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP-------LPPPPSE 363
P P PS+ G + P + SLSSS PL SP RSGP P PS+
Sbjct: 207 STTEPSPAARRRPSAGGGLQRP----ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262
Query: 364 ---------RPP---PPVRDPPGRSGPL------------PPPPPVSRNGSTSRALPATP 399
RPP PP +D GPL PP P + T + PATP
Sbjct: 263 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATP 322
Query: 400 QLPSRSGVDSPRSG------PRPPL------PPDRPSA------GAPPPPPPSTSIRNGF 441
+ + + SP P PPL PP P A APP PP S +
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382
Query: 442 QDSP-CEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRR--ERGAPPL 498
SP + P S PPP P VQ S P+ + S + ++ APPL
Sbjct: 383 TPSPQAPNALAVHLLQAPFS--PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440
Query: 499 --PPIP 502
PP P
Sbjct: 441 QVPPSP 446
Score = 45.8 bits (107), Expect = 9e-05
Identities = 62/252 (24%), Positives = 88/252 (34%), Gaps = 53/252 (21%)
Query: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPS------SSGNDETPRLPQRNLSLSSSTPPLPS 350
TP A P PP RP PPP+ P+ ++G L +R + +T P +
Sbjct: 16 TPAARAPGLLTPRPPGSPRP-PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 351 PGRSGPL----PP--------PPSERPPPPVRDPPGRSGPLPPPPPVSRNG--------- 389
P R+GP PP PP++ P PGR+ P P+ + G
Sbjct: 75 P-RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPP----------------DRPSAGAPPPPP- 432
+ +A A + +G SGP P P RP+ A P PP
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193
Query: 433 --PSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNR 490
P S+ + + S E +R L P ++S S S + S
Sbjct: 194 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP-----ASRSLSSSATPLSSPARSGP 248
Query: 491 RERGAPPLPPIP 502
RG P P P
Sbjct: 249 SARGTPRAPAHP 260
Score = 36.2 bits (82), Expect = 0.071
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 14/99 (14%)
Query: 342 SSSTPPLPSPGRSGPLPPPPSERPPPPVRDPP----GRSGPLPPPPPVSRNGSTSRALPA 397
++ TP +PG P PP RPPPPV G +G + P R G A
Sbjct: 13 AARTPAARAPGLLTPRPPGS-PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA--T 69
Query: 398 TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTS 436
P+ +PR+GP P G PP +TS
Sbjct: 70 IPE-------SAPRAGPTRTSRPPASGRGERAPPAKNTS 101
Score = 29.6 bits (65), Expect = 6.7
Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 8/90 (8%)
Query: 2 PVPPPPAP------PPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRS 55
P PAP P P T + ++ + A L ++ G V + S
Sbjct: 673 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLS 732
Query: 56 APILDKPKGAGAGGGGGGFGG--GGGFGGG 83
+L AGG GGG GG GGG GG
Sbjct: 733 RTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 762
Score = 29.3 bits (64), Expect = 8.7
Identities = 14/25 (56%), Positives = 14/25 (56%)
Query: 65 AGAGGGGGGFGGGGGFGGGGGGGGG 89
A A G GG GGG G GGG GG
Sbjct: 738 AAAEGAAGGSGGGPGGAEGGGVTGG 762
Score = 29.3 bits (64), Expect = 8.7
Identities = 13/26 (50%), Positives = 13/26 (50%)
Query: 75 GGGGGFGGGGGGGGGGSFGGGGPPGL 100
G GG GGG GG GG GG L
Sbjct: 742 GAAGGSGGGPGGAEGGGVTGGARAAL 767
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 119 bits (297), Expect = 8e-27
Identities = 120/418 (28%), Positives = 153/418 (36%), Gaps = 78/418 (18%)
Query: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPP-------GGRSTSAKPF 141
GGS G G P + +P L + G RPP P G S S P
Sbjct: 540 GGSEGAGAAPCPPNPANSWVPGL-------SPGGSRRPPRSPERTLSPSSGYSSQSGTPT 592
Query: 142 SPPSGPGRFPVPSPGHRSGPPEPQR-NRMPPPRPDVGSKPDSI----PPPVPST---PRP 193
PP G P SPG ++ PP+P+R + P V S S+ P PS P+
Sbjct: 593 LPPKGLAG-PPASPG-KAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650
Query: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253
+ PP P P SP P+ P P AL ++ P+S++ PP P
Sbjct: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP 710
Query: 254 PTPSRALDDKP-------PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
T L + P PPP PP PS H PPPPP V P S +++
Sbjct: 711 QTTLTPLQESPVISKDQSPPPSPP----PSYH----PPPPPTKKPEVVVEAPSASETAEE 762
Query: 307 P------PPPPPPSRPG--------PPP-------LPPSSSGNDETPRLPQRNLSLSSST 345
P PPPPPP+ PPP P +G +P L + SSS
Sbjct: 763 PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822
Query: 346 PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV--SRNGSTSR-------ALP 396
L P PPP+ P P PG LP PV S+ G R P
Sbjct: 823 TALQIQPPGSP-DPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881
Query: 397 ATPQLPSRSGVDSPRSGPRPPLPPDRP--------SAGAPPPPPPSTSIRNGFQDSPC 446
+ Q+ V +P P P L P P S A P P PS+ + + C
Sbjct: 882 SLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKAC 939
Score = 89.0 bits (219), Expect = 9e-18
Identities = 118/419 (28%), Positives = 152/419 (36%), Gaps = 95/419 (22%)
Query: 85 GGGGGGSFGGGGPPGLG---GLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF 141
GG G GS GG + +G RS + R RPP P S +
Sbjct: 457 GGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKL----KRPPPPPRRTHSLHQRGL 512
Query: 142 SPPSGPGRFP----------VPSPGHRSG---------PPEPQRNRMPPPRPDVGSKPDS 182
+ P GP P +P P G PP P + +P P +P
Sbjct: 513 AVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPR 572
Query: 183 IPPPVPSTPRPIQSSPHNRGSPPVP----GGPRQPSPGPTPPPFPGNRGTALG--GGSIR 236
P T P G+P +P GP SPG PP P R T+L G S+
Sbjct: 573 SPE---RTLSPSSGYSSQSGTPTLPPKGLAGP-PASPGKAQPPKP-ERVTSLRSPGASVS 627
Query: 237 QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS 296
S S S S+ P PS D P P+G+R +PP P K P P
Sbjct: 628 SSLTSLCSSSSD-----PAPS---DRSGPQILTPLGDR-----FVIPPHP----KVPAPF 670
Query: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSS-GNDETPRLPQRNLSLSSSTPPLPSPGRSG 355
+P PS P P + P P P S++ + ++P PQ L+ +P +
Sbjct: 671 SPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPP 730
Query: 356 PLPPPPSERPPPPVRDP------PGRS----GPL------PPPPPVSRNGSTSRA----- 394
P PPP PPPP + P P S PL PPPPP S A
Sbjct: 731 PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPP 790
Query: 395 -----LPATPQLPSRSG----VDSPRSGP--------RPPLPPDRPSAGAPPPPPPSTS 436
A+P+ SG V SP + +PP PD P APP P P++S
Sbjct: 791 EEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP--APPAPAPASS 847
Score = 77.0 bits (188), Expect = 4e-14
Identities = 102/425 (24%), Positives = 143/425 (33%), Gaps = 73/425 (17%)
Query: 121 SGGSRPPLLPPGGRSTSAKPF--SPPSGPGRFPVPSPGHRSGPPEPQRN-RMPPPRP--- 174
S S + PP G S P S + S G SG R + PPP P
Sbjct: 445 STASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRT 504
Query: 175 -DVGSKPDSIPP-PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGG 232
+ + ++P P+ P+P + PP GG P PP + L
Sbjct: 505 HSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSP 564
Query: 233 GSIRQSP------LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPP 286
G R+ P LS SS +S++ P P + L P P +A PP P
Sbjct: 565 GGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPG-----------KAQPPKP 613
Query: 287 PQNNKPPVPSTPRPSASSQ---APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSS 343
+ P S+ + + P P R GP L P P
Sbjct: 614 ERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPH---------- 663
Query: 344 STPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPS 403
P +P+P PPP R P P P + P P PVS ++ ++ P TPQ
Sbjct: 664 --PKVPAPFS----PPPSKPRSPNPA--APALAAPAVVPGPVSTTDASPQS-PPTPQTTL 714
Query: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPPP---PSTSIRNGFQDSPCEDEWESRFYFHP-- 458
+SP PP P + PPPPP P + E+ + + P
Sbjct: 715 TPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP 774
Query: 459 ---------ISDLPPPEPYVQTTKS------------YPSKLARNESRSGSNRRERGAPP 497
++D PPPE + S S A + S + + G+P
Sbjct: 775 PAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPD 834
Query: 498 LPPIP 502
PP P
Sbjct: 835 PPPAP 839
Score = 68.2 bits (165), Expect = 2e-11
Identities = 81/306 (26%), Positives = 112/306 (36%), Gaps = 61/306 (19%)
Query: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRS------GPPEPQRNRMPPPRPDVGS-KPDSI 183
P T+ +P P+ P P P+P + PPE + P P S P+ +
Sbjct: 754 PSASETAEEPLQDPNWPPP-PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV 812
Query: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP------PFPGNRGTALGGGSIRQ 237
P S+ GSP P P P+P + P P G + GGG R+
Sbjct: 813 SSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPRE 872
Query: 238 ---SPLSSSSPFS-------NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP 287
+PL + S P PTP+ P P P+ R ++ A P P P
Sbjct: 873 DVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG----PSAPQKPL--RRALSGRASPVPAP 926
Query: 288 QNN-----KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG--------------- 327
+ + S S A P PP + P PP P S++
Sbjct: 927 SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERP 986
Query: 328 -NDETPRLPQRNL-----SLSSSTPPLPSPGRSGPLPPPPSERP----PPPVRDPPGRSG 377
+ ET QRNL S+S PP +P +S PPP + +P PPP R+
Sbjct: 987 VSPETQADLQRNLVAELRSISEQRPP-QAPKKSPKAPPPVARKPSVGVPPPASPSYPRAE 1045
Query: 378 PLPPPP 383
PL PP
Sbjct: 1046 PLTAPP 1051
Score = 53.9 bits (128), Expect = 3e-07
Identities = 73/295 (24%), Positives = 104/295 (35%), Gaps = 45/295 (15%)
Query: 106 AGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEP 164
+G P+L S+ + S + + PPG P PP+ P P S PGH + P+
Sbjct: 806 SGSPELVSSPAASSSSATALQ-IQPPGS------PDPPPAPPAPAPASSAPGHVAKLPQK 858
Query: 165 Q----RNRMPPPRPDVGSK-----------------PDSIPPPV--PSTP-RPIQSSPHN 200
+ PPR DVG+ P P P PS P +P++ +
Sbjct: 859 EPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSG 918
Query: 201 RGSP-PVPGGPRQPSPGPTPPPFPGNRG--TALGGGSIRQSPLSSSSPFSNRPPLPPTPS 257
R SP P P + + G +A G P SP S + S
Sbjct: 919 RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGS 978
Query: 258 RALDDKPPPPPPP--------VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP 309
R L + P P V SI + P P ++ K P P +PS PPP
Sbjct: 979 RKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVG--VPPP 1036
Query: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER 364
P P P ++G T +R L+ + L P LP S++
Sbjct: 1037 ASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQK 1091
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 118 bits (296), Expect = 1e-26
Identities = 115/366 (31%), Positives = 146/366 (39%), Gaps = 63/366 (17%)
Query: 116 NRDNDSGGSRPPLLPPGGRSTSAKP--FSPPSGPGRFPVPSPGHRSGPPEP-QRNRMPPP 172
N SG P PP +S S KP PP+G VP P PP P P
Sbjct: 675 NASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV----VPPPPPPPPPPTPGSAMAQLKP 730
Query: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGG 232
P S P PP P +Q + +PP P P P P P PP P +
Sbjct: 731 APCAPSLPQFSAPPPPLKIHQVQHI--TQVAPPTPPPP-PPIPAPLPPQAPPKPLVTIPA 787
Query: 233 GSIRQSP---LSSSSPFSNRPPLPPT------PSRALDDKPPPPPPPVGNRPSIHRE--- 280
+ ++ ++ ++P + PP+PP P+ + PP PP PV P++ ++
Sbjct: 788 PTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP-PTLPKQQSF 846
Query: 281 -AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP--PLP--------------- 322
A PPP P + PVPS + AS Q PPPP PP+ P P+P
Sbjct: 847 CAKPPPSPLS---PVPSVVKQIAS-QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKP 902
Query: 323 ---PSS---SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS 376
PSS D P P+ +L PP PSP + P PPPP+ P P PG+
Sbjct: 903 KWQPSSIPVPSPDFPPPPPESSLVF---PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKK 959
Query: 377 -------GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP 429
G PPP RN S + A P R VDS S PP PS P
Sbjct: 960 TSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLP 1019
Query: 430 PP--PP 433
PP PP
Sbjct: 1020 PPAAPP 1025
Score = 110 bits (274), Expect = 4e-24
Identities = 125/490 (25%), Positives = 167/490 (34%), Gaps = 119/490 (24%)
Query: 102 GLFQAGMPKLRSTANRDNDSGGS-RPPLLPPGGRSTSAKPFSPPSGPG-RFPVPSPGHRS 159
G + +P+ +S + +DSG S P +S + FS G + S
Sbjct: 537 GSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARME 596
Query: 160 GPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTP 219
P + +PP P +P + P S P P P P P P P P P P
Sbjct: 597 SMNRPYTSLVPPLSP----QPKIVTPYTASQPSPPLPPP------PPPPPPPPPPPPPPP 646
Query: 220 PPFPGNRGTALGGGS---------IRQSPLSSSSPFSNRPPLPPT-------------PS 257
PP P + G + R S S +PP PP P+
Sbjct: 647 PPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPN 706
Query: 258 RALDDKPPPPPPPVGN-----------RPSIHREAVPPPPPQNNK--------PPVPSTP 298
+ PPPPPPP PS+ + + PPPP + ++ PP P P
Sbjct: 707 GVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766
Query: 299 RPSASSQAPPPPPPP--SRPGP-------------------PPLPPSSSGNDETPRLPQR 337
P + P PP P + P P PP+PP+ + P P
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK----KQPAFPAS 822
Query: 338 NLSLSSSTPPLPSPGRSGP------LPPPPSERPP------------PPVRDPPGRSGPL 379
+ S TPP+P P + P PPPS P PP PP
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP 882
Query: 380 PPPPPVSRNGSTSRALPATPQ-LPSRSGVDSPRSGPRP-------PLPPDRPSAGAPPPP 431
P P + + A+ A P+ PS V SP P P P PP P PPPP
Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP 942
Query: 432 PPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRR 491
PP+ S SP + ++ P PPP P RN S S+
Sbjct: 943 PPTASPTPDKSGSPGKKTSKTS---SPGGKKPPPTP------------QRNSSIKSSSGA 987
Query: 492 ERGAPPLPPI 501
E P P +
Sbjct: 988 EHPEPKRPSV 997
Score = 83.2 bits (204), Expect = 5e-16
Identities = 94/345 (27%), Positives = 118/345 (34%), Gaps = 47/345 (13%)
Query: 126 PPLLPPGGRSTSAKPF-------SPPS-------GPGRFPVPSPGHRSGPPEPQRNRMPP 171
PP PP S KP SPP+ P PVPSP PPE PP
Sbjct: 871 PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930
Query: 172 PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALG 231
P P +P P P P +P GSP G PPP P R +++
Sbjct: 931 P-------PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP-QRNSSIK 982
Query: 232 GGSIRQSPL----SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG--------NRPSIHR 279
S + P S S S P + S + + PPP PP N P + +
Sbjct: 983 SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042
Query: 280 E----AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL- 334
+ A P K V P P + S PPPPP P PP P+ + +P++
Sbjct: 1043 QGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA 1102
Query: 335 -----PQRNLSLS-SSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN 388
PQ+ +S PP P R+ +E P P P +S
Sbjct: 1103 VVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQ 1162
Query: 389 GSTSRALPATPQLPS--RSGVDSPRSGPRPPLPPDRPSAGAPPPP 431
L T Q S R G S R P A PPPP
Sbjct: 1163 PGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPP 1207
Score = 75.5 bits (184), Expect = 1e-13
Identities = 78/253 (30%), Positives = 93/253 (36%), Gaps = 40/253 (15%)
Query: 273 NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLP---PSSSGND 329
NRP + VPP PQ + +PS PPPPPPP P PPP P PS S
Sbjct: 599 NRP--YTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPS 656
Query: 330 ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP------SERPPPPVRDPP-GRSGPLPPP 382
P + S+ T + SG L PP S+ P + PP G P PPP
Sbjct: 657 AGSAAPM-FVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP 715
Query: 383 PPVSRNGSTSRAL---PATPQLPSRSGVDSPR--------SGPRPPLPPDRPSAGAPPPP 431
PP GS L P P LP S P + PP PP P AP PP
Sbjct: 716 PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPP 775
Query: 432 --PPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSN 489
PP + P ++ + P P P V K P+ A S
Sbjct: 776 QAPPKPLV-----TIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS--- 827
Query: 490 RRERGAPPLPPIP 502
PP PP+P
Sbjct: 828 ------PPTPPVP 834
Score = 53.1 bits (126), Expect = 6e-07
Identities = 59/199 (29%), Positives = 72/199 (36%), Gaps = 55/199 (27%)
Query: 333 RLPQRNLSLSSSTPPL-PSPGRSGPL----PPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387
R+ N +S PPL P P P P PP PPPP PP P PPPPP
Sbjct: 594 RMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPP---PPPPPPPPPPPPPPLP 650
Query: 388 NGSTSRALPATPQLPSRSGVD-----SPRSG-----PRPP------------LPPDRPSA 425
+ S A A P S + S SG P PP +PP+
Sbjct: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710
Query: 426 GAPPPPPPST--SIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNE 483
PPPPPP T S + +PC P PPP P K+ + +
Sbjct: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSL-------PQFSAPPP----------PLKIHQVQ 753
Query: 484 SRSGSNRRERGAPPLPPIP 502
+ + APP PP P
Sbjct: 754 HIT------QVAPPTPPPP 766
Score = 49.3 bits (116), Expect = 8e-06
Identities = 109/435 (25%), Positives = 140/435 (32%), Gaps = 136/435 (31%)
Query: 2 PVPPP---PAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58
P PPP PAPPPPP T PT +K+ S GKK KT S+P
Sbjct: 928 PPPPPSPVPAPPPPP----PPTASPTPDKSG-----------SPGKKTSKT-----SSP- 966
Query: 59 LDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRD 118
GG PP P + ++
Sbjct: 967 ----------------------------------GGKKPP----------PTPQRNSSIK 982
Query: 119 NDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGS 178
+ SG P P S +K F+PP+ G P + +PPP
Sbjct: 983 SSSGAEHPEPKRPSVDSLVSK-FTPPAESG--------------SPSKETLPPP------ 1021
Query: 179 KPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
PP P N +PG +Q P G G S+ +
Sbjct: 1022 ----AAPPKP--------GKLNLSGVNLPGVLQQGCVSAKAPVLSGR-----GKDSVVEF 1064
Query: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQN------NKP 292
P S S+ PP PP L PP P V + + + AV P PQ K
Sbjct: 1065 PSPPSD--SDFPPPPPETELPL---PPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKA 1119
Query: 293 PVPSTPRPSAS---SQAPPPPPPPSRPGPPPLP--PSSSGNDETPRLPQRNLSLSSSTPP 347
P P+ P+ + S +QA P P +P P SS + + L N +L
Sbjct: 1120 PPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK--- 1176
Query: 348 LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407
S R G L S P D LPPPPP + + SG
Sbjct: 1177 --SITRHGSLSSRMSRAEPTATMDDMA----LPPPPPELLSDQQKAGYGGS----HISGY 1226
Query: 408 DSPRSGPRPPLPPDR 422
+ R GP PP PP R
Sbjct: 1227 ATLRRGP-PPAPPKR 1240
Score = 32.0 bits (71), Expect = 1.3
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 2 PVPPPPAPPPPPTFALANTEKPT 24
P PPPP PPPPP L + P+
Sbjct: 634 PPPPPPPPPPPPPPPLPSQSAPS 656
Score = 32.0 bits (71), Expect = 1.3
Identities = 11/12 (91%), Positives = 11/12 (91%)
Query: 3 VPPPPAPPPPPT 14
VPPPP PPPPPT
Sbjct: 709 VPPPPPPPPPPT 720
Score = 31.2 bits (69), Expect = 2.3
Identities = 10/13 (76%), Positives = 11/13 (84%)
Query: 1 MPVPPPPAPPPPP 13
+P PPPP PPPPP
Sbjct: 628 LPPPPPPPPPPPP 640
Score = 30.4 bits (67), Expect = 3.9
Identities = 10/12 (83%), Positives = 10/12 (83%)
Query: 2 PVPPPPAPPPPP 13
P PPPP PPPPP
Sbjct: 630 PPPPPPPPPPPP 641
Score = 30.4 bits (67), Expect = 3.9
Identities = 10/12 (83%), Positives = 10/12 (83%)
Query: 2 PVPPPPAPPPPP 13
P PPPP PPPPP
Sbjct: 631 PPPPPPPPPPPP 642
Score = 30.4 bits (67), Expect = 3.9
Identities = 10/12 (83%), Positives = 10/12 (83%)
Query: 2 PVPPPPAPPPPP 13
P PPPP PPPPP
Sbjct: 632 PPPPPPPPPPPP 643
Score = 30.4 bits (67), Expect = 3.9
Identities = 10/12 (83%), Positives = 10/12 (83%)
Query: 2 PVPPPPAPPPPP 13
P PPPP PPPPP
Sbjct: 633 PPPPPPPPPPPP 644
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/18 (61%), Positives = 13/18 (72%)
Query: 1 MPVPPPPAPPPPPTFALA 18
+P PPPP PPP P A+A
Sbjct: 709 VPPPPPPPPPPTPGSAMA 726
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 116 bits (290), Expect = 5e-26
Identities = 107/337 (31%), Positives = 129/337 (38%), Gaps = 71/337 (21%)
Query: 148 GRFPVP-SPGHRSGP--------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
G PVP S G SGP P P PP P + S S PP + S P +S P
Sbjct: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS--ESRP 378
Query: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT--P 256
++ PGGP P P P P G GG ++ +P P+ PP P P
Sbjct: 379 YHGMHGGGPGGP-GGGPHSFPHPLPSLTG-GHGGHPMQHNPNGPPPPWMQPPPPPMNQGP 436
Query: 257 SRALDDKPPP------------------------PPPPVGNRPSIHREAVPPPPPQNNKP 292
PPP PPPP+G P PPPPP P
Sbjct: 437 HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP------PPPPPSGQPP 490
Query: 293 PVPSTPRP--SASSQAPPPPPPP--SRPGPPPLP--------PSSSGNDETPRLPQRNLS 340
P PS P P Q PPPPPPP S PLP +S+G P Q+ +
Sbjct: 491 PPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAA 550
Query: 341 LSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400
++S G +P PP +PP PPG P PPPPP S + P P
Sbjct: 551 AAASPGAPQMQGNPTMVPLPPGVQPPL----PPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606
Query: 401 LPSRSGVDSPRSG--PRPP--LPPDRPSAGAPPPPPP 433
+ + V G PP +PP APPPPPP
Sbjct: 607 MDPSNFVTMMGMGVAGMPPFGMPP------APPPPPP 637
Score = 89.0 bits (219), Expect = 9e-18
Identities = 99/361 (27%), Positives = 120/361 (33%), Gaps = 104/361 (28%)
Query: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
P P PPPP + + P +N S P +
Sbjct: 346 PAAPANNPPPPSLMSTTQSRPPWMN----------------------------SGPSESR 377
Query: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121
P + G G G GG GGG SF P GG G P + N +
Sbjct: 378 P-----------YHGMHGGGPGGPGGGPHSFPHPLPSLTGG--HGGHPM------QHNPN 418
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQ---------------- 165
G P + PP PP G P PGH PP Q
Sbjct: 419 GPPPPWMQPP----------PPPMNQGPHP---PGHHGPPPMDQYLGSTPVGSGVYRLHQ 465
Query: 166 -RNRMPPP----RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220
+ MPPP P P PPP PS P P + PP P P TP
Sbjct: 466 GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPP--PSSSMASSTPL 523
Query: 221 PFPGNRGT---ALGGGSI----RQSPLSSSSP----FSNRP---PLPP--TPSRALDDKP 264
P+ N T + G GSI +Q +++SP P PLPP P P
Sbjct: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583
Query: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324
PPPPPP G+ ++ PPPPP + PS PP P PPP PP
Sbjct: 584 PPPPPPPGSAGMMYAPPPPPPPPMD-----PSNFVTMMGMGVAGMPPFGMPPAPPPPPPQ 638
Query: 325 S 325
+
Sbjct: 639 N 639
Score = 82.4 bits (202), Expect = 9e-16
Identities = 90/342 (26%), Positives = 117/342 (34%), Gaps = 95/342 (27%)
Query: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP--------PPPVGNRPSIHR-- 279
LG + S S+S P + P P+ ++ PPP PP + + PS R
Sbjct: 320 LGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
Query: 280 ---------------EAVPPPPPQ----NNKPPVPSTPR-PSASSQAPPPPP------PP 313
+ P P P + P+ P P PPPPP PP
Sbjct: 380 HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP 439
Query: 314 SRPGPPPL------PPSSSG----NDETPRLPQRNLSLSSSTPPLPS----PGRSGPLPP 359
GPPP+ P SG + +P + + PP PS P SGPLPP
Sbjct: 440 GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPP 499
Query: 360 PPSER----PPPPVRDPPGRSGPLP---------------PPPPVSRNGSTSRALPATPQ 400
++ PPPP S PLP PP + + + A P PQ
Sbjct: 500 WQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQ 559
Query: 401 LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPIS 460
+ + G +PPLPP GAPPPPPP G +P
Sbjct: 560 MQGNPTMVPLPPGVQPPLPP-----GAPPPPPPPPPGSAGMMYAP--------------- 599
Query: 461 DLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
PPP P + PS + G PP PP P
Sbjct: 600 -PPPPPPPMD-----PSNFVTMMGMGVAGMPPFGMPPAPPPP 635
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 115 bits (288), Expect = 9e-26
Identities = 125/432 (28%), Positives = 148/432 (34%), Gaps = 65/432 (15%)
Query: 47 KKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGG-GGGGGGGGSFGGGGPPGLGGLFQ 105
+K +R AP P+GA G G GG G G G GG GS G GPPG G
Sbjct: 502 EKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQG--- 558
Query: 106 AGMPKLRSTANRDNDSGGSRPPLLP-----PGGRSTSAKP-----FSPPSGPGRFPVPSP 155
+ R G S P P PG + P P GPG P
Sbjct: 559 --------ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610
Query: 156 GHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP 215
+GP P P P G K D+ PP P+ +Q P G P G P +P P
Sbjct: 611 NGETGPQGP-----PGPTGPGGDKGDTGPP----GPQGLQGLPGTGGPPGENGKPGEPGP 661
Query: 216 --GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGN 273
P PG +G A G R P + +P PP P PP PP
Sbjct: 662 KGDAGAPGAPGGKGDA-GAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAG 720
Query: 274 RPSI-----HREAVPPPPPQNNKPPVPSTPRPSA--SSQAPPPPPPPSRPGPPPLPPSSS 326
P + R + P P+ +K P P P P P P P P
Sbjct: 721 TPGLQGMPGERGGLGSPGPKGDKGE-PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK 779
Query: 327 GNDETPRLPQRNLSLSS------STPPLP-----SPGRSGP--------LPPPPSERPPP 367
G P LP S + PP P +PG++G P E PP
Sbjct: 780 GEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP 839
Query: 368 PVRDPPGRSGPLPPPPPVSRNGST-SRALPATPQLPSRSGVDSP---RSGPRPPLPPDRP 423
V PPG SGP PP P G S P P G+ P P PP P P
Sbjct: 840 GVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSP 899
Query: 424 SAGAPPPPPPST 435
PP P +T
Sbjct: 900 GKDGPPGPAGNT 911
Score = 100 bits (249), Expect = 3e-21
Identities = 120/405 (29%), Positives = 136/405 (33%), Gaps = 61/405 (15%)
Query: 56 APILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPG-LGGLFQAGMPKLRST 114
A I P GA G G G G G GG G G G G PG G +AG+P +
Sbjct: 401 AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460
Query: 115 ANRDNDSGGSRPP---LLPPGGRSTSAKPFSPPSGPGRFP----------VPSP-GHRSG 160
D G P LP A F P+GP P P P G R
Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520
Query: 161 PPEPQRNRMP-------PPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR-Q 212
EP R+ +P P G D P P P R PP P GPR Q
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP------PGSQGESGRPGPPGPSGPRGQ 574
Query: 213 PS----PGPT----PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP 264
P PGP P G RG GG + P + PP P P D
Sbjct: 575 PGVMGFPGPKGNDGAPGKNGERG-GPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTG 633
Query: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324
PP P + P PP +N K P P P + AP P G P
Sbjct: 634 PPGPQGLQGLP-----GTGGPPGENGK---PGEPGPKGDAGAPGAPGGKGDAGAP----- 680
Query: 325 SSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP-PPSERPPPPVRDPPGRSGPLPPPP 383
G P L + PP P G+ PP PP P ++ PG G L P
Sbjct: 681 --GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738
Query: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428
P G P P G D PR GP P+ P P AG P
Sbjct: 739 PKGDKGE-----PGGPGADGVPGKDGPR-GPTGPIGPPGP-AGQP 776
Score = 100 bits (249), Expect = 3e-21
Identities = 121/406 (29%), Positives = 143/406 (35%), Gaps = 84/406 (20%)
Query: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121
P G G G G G G GG G G+ G GPPGL AG P LR
Sbjct: 650 PGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL-----AGAPGLR--------- 695
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS----PGHRS--GPPEPQRNRMPPPRPD 175
GG+ PP P GG+ + PP PG P PG R G P P+ ++ P P
Sbjct: 696 GGAGPP-GPEGGKGAA----GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPG 750
Query: 176 VGSKPDSIPP-----PV-PSTPRPIQSSPHNRGSPPVPG--GPRQPSPG-------PTPP 220
P P P+ P P G+P +PG GPR SPG P P
Sbjct: 751 ADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPR-GSPGERGETGPPGPA 809
Query: 221 PFPGNRGT--ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278
FPG G GG R +P P + P + PP P G R S
Sbjct: 810 GFPGAPGQNGEPGGKGERGAPGEKGE--GGPPGVAGPPGGSGPAGPPGPQGVKGERGS-- 865
Query: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN 338
P P P P P S+ P PP P PG PP +GN P
Sbjct: 866 ----PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG-PPGPAGNTGAP------ 914
Query: 339 LSLSSSTPPLPSPGRSGPL--PPPPSERPPPPVRDPPGRSGPL-------------PPPP 383
SPG SGP P E+ P + PPG GPL PP
Sbjct: 915 ----------GSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGM 964
Query: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP-LPPDRPSAGAP 428
P R + + P +G+ R P P LP +AG P
Sbjct: 965 PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP 1010
Score = 94.0 bits (232), Expect = 3e-19
Identities = 127/476 (26%), Positives = 164/476 (34%), Gaps = 75/476 (15%)
Query: 32 GRNALLSDI-SKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGGGG-GGG 89
GRN + + G K + + + AP P+GA G G G G G G G
Sbjct: 270 GRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD 329
Query: 90 GSFGGGGPPGLGG----------LFQAGMPKLRSTANRDNDSG-----GSRPPLLPPG-- 132
G G GPPG G + AG P + + G G++ P PPG
Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN 389
Query: 133 ---GRSTSAKPFSPPSGPGRF-----PVP-----SPGHRSGPPEPQRNRM---PPPRPDV 176
G P P PG P P +PG R G EP +N P PR
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR--- 446
Query: 177 GSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP----------GPT-PPPFPGN 225
G + ++ P VP + GSP PG P GP P PG
Sbjct: 447 GERGEAGIPGVPGA----KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE 502
Query: 226 RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPS-RALDDKPPPP-----PPPVGNRPSIHR 279
+G A G+ + ++ R +P P R + P P P P G++ R
Sbjct: 503 KGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGR 562
Query: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRP-GPPPLPPSSSGNDETPRLPQRN 338
P P +P V P P + AP P GP P P + P+ P
Sbjct: 563 PGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGP--- 619
Query: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSG-PLPPPP------PVSRNGST 391
T P G +GP P P + P PPG +G P P P P + G
Sbjct: 620 ---PGPTGPGGDKGDTGP-PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG 675
Query: 392 SRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCE 447
P P +G R G PP P+ A PP PP + G Q P E
Sbjct: 676 DAGAPGERGPPGLAGAPGLRGGAGPP-GPEGGKGAAGPPGPPGAAGTPGLQGMPGE 730
Score = 87.0 bits (214), Expect = 4e-17
Identities = 119/417 (28%), Positives = 146/417 (35%), Gaps = 70/417 (16%)
Query: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121
P G G G G G G G G G G GPPG G P A +D +S
Sbjct: 179 PGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGP-----AGKDGES 233
Query: 122 GGSRPPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPGHR--SGPPEPQRNRMPPPRPDVGS 178
G RP PG R P P+G FP GHR G + P
Sbjct: 234 G--RPG--RPGERGLPGPPGIKGPAGIPGFP-GMKGHRGFDGRNGEKGETGAPGLKGENG 288
Query: 179 KPDSIPPPVPSTPRPIQSSPHNRGSPPVPG--GPR--------QPSPGPTPPP----FPG 224
P P P PR +P RG P +PG G R PGP PP FPG
Sbjct: 289 LPGENGAPGPMGPR---GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPG 345
Query: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP- 283
+ G A G SP S+ +P P P + A + PP PP + P E P
Sbjct: 346 SPG-AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGA---QGPPGPPGINGSPGGKGEMGPA 401
Query: 284 -------------PPPP--QNNKPPV---PSTPRPSASSQAPPPPPPPSRPGPPPLP--P 323
PP P N P + P + + P P G P +P
Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461
Query: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP--PSERPPPPVRDPPGRSGPLPP 381
G D +P P N L + +PG GP P P E+ P R PG +GP
Sbjct: 462 GEDGKDGSPGEPGAN-GLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520
Query: 382 PPPVSRNGSTS----RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
R+G R +P +P P G +P P + +G P PP PS
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSPGGPGSDG--------KPGPPGSQGESGRPGPPGPS 569
Score = 87.0 bits (214), Expect = 4e-17
Identities = 114/405 (28%), Positives = 135/405 (33%), Gaps = 70/405 (17%)
Query: 66 GAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGL----GGLFQAGMPKLRSTANRDNDS 121
G G G G G GG G G G G GGPPG+ GG AG P +
Sbjct: 807 GPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP 866
Query: 122 GGSRPPLLPPGGRSTSAKPFSP--PSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
GG P G R P S P PG P SPG + GPP P N P P V
Sbjct: 867 GGPGAAGFP-GARGLPGPPGSNGNPGPPG--PSGSPG-KDGPPGPAGNTGAPGSPGV--- 919
Query: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP----GPT-------PPPFPGNRGT 228
S P+ P +GSP G P P P G T PP PG RG+
Sbjct: 920 ---------SGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGS 970
Query: 229 ALGGGSIRQSPLSSSSPFSNR--PPLPP-TPSRALDDKPPPPPPPVGNRPSIHREAVP-- 283
G +S ++ S PP P P A P G+ R+ P
Sbjct: 971 PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030
Query: 284 ------------PPPPQNNKPPVPSTPRPSASSQ--------APPPPPPPSRPGPPPLPP 323
P P + PP P P + + A P P SR P P P
Sbjct: 1031 KGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090
Query: 324 SSSGNDETPR-----LPQRNLSLSSSTPPLPSP-GRSGPL--PPPPSERPPPPVRDPPGR 375
+ R R + P P P G+ G + P P R P PPG+
Sbjct: 1091 RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGK 1150
Query: 376 SG----PLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP 416
G P P PP R R +P P + G P P P
Sbjct: 1151 DGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195
Score = 69.7 bits (169), Expect = 6e-12
Identities = 91/318 (28%), Positives = 103/318 (32%), Gaps = 75/318 (23%)
Query: 56 APILDKPKG-AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGG-LFQAGMPKLRS 113
+P D P G AG G G G G G G G GS G GPPG G L AG+ R
Sbjct: 898 SPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG 957
Query: 114 TANRDNDSGGSRPPLLPPGGRSTSAKPFSP-------PSGPGRFP-----VPSPGHRSGP 161
A G P P G + S KP + P GP P PG P
Sbjct: 958 LAGPPGMPGPRGSPG-PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016
Query: 162 PE---PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPI-------------QSSPHNRGSPP 205
P R+ P + D G P P P P +S P P
Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAP 1076
Query: 206 VPGGPRQPSPGPTPPP-------------------FPGNRGTALGGGSI-RQSPLSSSSP 245
P G R +PGP P FPGN G G +Q + S P
Sbjct: 1077 GPAGSRG-APGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGP 1135
Query: 246 FSNRPPLPPTPSRALDDK-----PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
R P+ P+ D P PP P GNR E P P Q
Sbjct: 1136 AGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQ------------ 1183
Query: 301 SASSQAPPPPPPPSRPGP 318
P PP PP PGP
Sbjct: 1184 ------PGPPGPPGAPGP 1195
Score = 63.9 bits (154), Expect = 3e-10
Identities = 80/282 (28%), Positives = 96/282 (34%), Gaps = 45/282 (15%)
Query: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGP-RQPSPG-PTPPPFPGNRGTALGGGSIRQSPLS 241
PP P+ P Q +G P PG P R PG P P PG+ G S P +
Sbjct: 91 PPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQN 150
Query: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301
S + + L P P PP P PP + P P +P
Sbjct: 151 YSPQYDSYDVKSGVAVGGLAGYPGPAGPP----------GPPGPPGTSGHPGSPGSP--- 197
Query: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
Q PP P + P PP PP + G P + PG G LP PP
Sbjct: 198 -GYQGPPGEPGQAGPSGPPGPPGAIG-------PSGPAGKDGESGRPGRPGERG-LPGPP 248
Query: 362 SERPPPPVRDPPGRSGPLPPPPPVSRNGST-SRALPATPQLPSRSGVD---SPRSGP--- 414
+ P + PG G G T + L LP +G PR P
Sbjct: 249 GIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGER 308
Query: 415 -RPPLP---------PDRPSAGAP-PPPPPSTSIRNGFQDSP 445
RP LP R S G P PP PP T+ GF SP
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQPGPPGPPGTA---GFPGSP 347
Score = 56.6 bits (135), Expect = 5e-08
Identities = 57/175 (32%), Positives = 64/175 (36%), Gaps = 10/175 (5%)
Query: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121
P GA G G G G G G G G G G PG G A P+ D
Sbjct: 1040 PGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ---GPRGDKGE 1096
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPS-GPG--RFPVPSPGHRSGPPEPQRNRMPPPRPDVGS 178
G R G R P +P S GP + + SPG +GP P PP +
Sbjct: 1097 TGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGP-AGPRGPVGPSGPPGKDGTSG 1155
Query: 179 KPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
P I PP P R + S GSP PG P P P P P G G A G
Sbjct: 1156 HPGPIGPPGPRGNRGERGS---EGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAG 1207
Score = 47.8 bits (112), Expect = 2e-05
Identities = 44/162 (27%), Positives = 53/162 (32%), Gaps = 33/162 (20%)
Query: 293 PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLP--- 349
P P P + P PP P+RP P G+ P +P RN P +P
Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRN-----GDPGIPGQP 129
Query: 350 -SPGRSGP------LPPPPSERPPP-------------PVRDPPGRSGPLPPPPPVSRNG 389
SPG GP P P P + PG +GP PP P +G
Sbjct: 130 GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG 189
Query: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPP 431
P +P P G P PP P A P P
Sbjct: 190 H-----PGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGP 226
Score = 47.0 bits (110), Expect = 4e-05
Identities = 56/186 (30%), Positives = 71/186 (38%), Gaps = 31/186 (16%)
Query: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLP-- 322
P P P G ++ P PP +P P+ P P PP P R G P +P
Sbjct: 75 PNPEIPFGECCAV----CPQPPTAPTRP--PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQ 128
Query: 323 PSSSGNDETPRLPQ------RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS 376
P S G+ P + + +N S + + S G L P PP PPG S
Sbjct: 129 PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS 188
Query: 377 G-PLPPPPPVSRN--GSTSRALPATPQLPSRSGVDSPRSGP--------RPPLPPDRPSA 425
G P P P + G +A P+ P P G P SGP RP P +R
Sbjct: 189 GHPGSPGSPGYQGPPGEPGQAGPSGP--PGPPGAIGP-SGPAGKDGESGRPGRPGER--- 242
Query: 426 GAPPPP 431
G P PP
Sbjct: 243 GLPGPP 248
Score = 31.6 bits (70), Expect = 1.8
Identities = 41/170 (24%), Positives = 56/170 (32%), Gaps = 32/170 (18%)
Query: 341 LSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400
L P +P P PP+ P R PP GP P + P P
Sbjct: 72 LDCPNPEIPFGECCAVCPQPPTA----PTR-PPNGQGPQGP-----------KGDPGPPG 115
Query: 401 LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD-SPCEDEWESR------ 453
+P R+G P +P S G+P PP S G Q+ SP D ++ +
Sbjct: 116 IPGRNG--------DPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVG 167
Query: 454 -FYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
+P PP P T +P + + P PP P
Sbjct: 168 GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP 217
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 115 bits (288), Expect = 9e-26
Identities = 139/529 (26%), Positives = 179/529 (33%), Gaps = 87/529 (16%)
Query: 5 PPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKG 64
PP A PP P + A T P T A T+ + + P KG
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAA----------------TLPSPKGGPATPSLKG 1078
Query: 65 AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLF---QAGMPKLRSTANRDNDS 121
A GG G P GGL G P +
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
G + PP P G +T A +PPS G P P + P P PP P G
Sbjct: 1139 GLATPP--PKGAPTTPAA--TPPSPKGGLATPPP--KGAPTTPAAT---PPSPKGGLATP 1189
Query: 182 SIPPPVPSTPRPIQSSPHNRGSPPVP-GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
S P P+TP SP + P P G P P+ P P GG SP
Sbjct: 1190 S-PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK----------GGLATPSPK 1238
Query: 241 SSSSPFSNRPPLPPTPSRALDDKPPP---PPPPVGNRPSIHREAVPPP-----------P 286
+ + + PP P + PPP P PP PS+ PP P
Sbjct: 1239 GAPTTPAATPPSP----KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 287 PQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346
P P S P+ + + A PP P PG PP + + TP P+ +L ++TP
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354
Query: 347 PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSG 406
+ GP P E P PP P + GP PP R A+P+ P+
Sbjct: 1355 S----SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR----GPAIPSPKGDPTSPA 1406
Query: 407 VD--SPRSGPRPPLPPD---RPSAGAPPPP---------PPSTSIRNGFQDSPCEDEWES 452
V SP+ P P+ + PS G PP P+TS G +P +
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT 1466
Query: 453 RFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPI 501
P S PP P T S P K + + GAP LP +
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKK-------APATPAPMGAPTLPAV 1508
Score = 104 bits (260), Expect = 2e-22
Identities = 105/374 (28%), Positives = 137/374 (36%), Gaps = 72/374 (19%)
Query: 109 PKLRSTANRDNDSGGSRPPLLP-------------PGGRSTSAKPFSP-PSGPGRFPVPS 154
P + +A D G P+ P G + + A SP P P P PS
Sbjct: 809 PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPS 868
Query: 155 PGHRSGPPEPQRNRMPP---PRPDVGSKPDSIPPPVPSTPRPIQ--------SSPHNRGS 203
P P+ +PP P P V + P P P+TP P Q SSP +
Sbjct: 869 A---VTPLSPKGVTLPPKETPTPSVVNLP--FPKEGPATPAPKQAPALSMTSSSPKKARA 923
Query: 204 PPVPGG-PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262
P P G P PSP P P P + GG SP + +P + PP P
Sbjct: 924 TPAPKGIPASPSPKGAPTP-PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
Query: 263 KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG----- 317
K P PP A PP P+ P+TP P + PP PPS G
Sbjct: 983 KGAPTPP-----------AATPPSPKGG----PATPSPKGAP-TPPAVTPPSPKGSPAAT 1026
Query: 318 ---------PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP----LPPPPSER 364
P PPS G+ LP+ + ++T P P G + P P PP+
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 365 PPPP---VRDPPGRSGPLPP--PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLP 419
PP P P + P+PP PP + G + P P+ + SP+ G P P
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT-PPSPKGGLATPPP 1145
Query: 420 PDRPSAGAPPPPPP 433
P+ A PP P
Sbjct: 1146 KGAPTTPAATPPSP 1159
Score = 100 bits (250), Expect = 2e-21
Identities = 139/564 (24%), Positives = 190/564 (33%), Gaps = 93/564 (16%)
Query: 5 PPPAPPPPPTFALANTEKP----TLNKTEQAGRNALLSDISKGKKLKKTVT--NDRSAPI 58
PP A PP P LA T T + + L + KG T + +
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1164
Query: 59 LDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRST--AN 116
PKGA GG G + P GGL +T A
Sbjct: 1165 TPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224
Query: 117 RDNDSGGSRPPLLPPGGRST-SAKPFSPPSGPGRFP---VPSP---------GHRSGPPE 163
+ GG P P G +T +A P SP GP P P+P G + PP
Sbjct: 1225 PPSPKGGLATPS-PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 164 ---PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220
P + PP P G P + PP TP P + P +GSP P P+P P
Sbjct: 1284 KGAPNPAVVTPPSPKGG--PATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 221 PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP--TPSRALDDKPPPPPPPVGNRPSIH 278
P P +GT + S ++P S P PP TPS PP P G
Sbjct: 1341 PSP--KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG------ 1392
Query: 279 REAVPPPPPQNNKPPV--------PSTP-------RPSASSQAPPP-------------- 309
A+P P P V P+TP PS PP
Sbjct: 1393 -PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Query: 310 ----PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSS--STPPLPSPGRSGPLPPPPSE 363
P PS G P LP + + + P P++ + SS P P+P + LP
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511
Query: 364 RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP 423
P P R P+ P + + + P +P V SP+ P P P + P
Sbjct: 1512 SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP 1571
Query: 424 S------AGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477
+ A +PP PST ++ +P E P P P + + P+
Sbjct: 1572 ATPSSKEASSPPAVTPST-----YKGAPSPKE----LLIPPAVTSPSP----KEAPTPPA 1618
Query: 478 KLARNESRSGSNRRERGAPPLPPI 501
+ + + +G P PP+
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPV 1642
Score = 85.9 bits (211), Expect = 8e-17
Identities = 83/306 (27%), Positives = 110/306 (35%), Gaps = 34/306 (11%)
Query: 153 PSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSS--PHN-------RGS 203
PSP S P+ +R PP + PD+ + S P+++S P N + S
Sbjct: 794 PSPLGVSVSPQTKR----PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849
Query: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263
P P PSP P P + T L + P + +P P P K
Sbjct: 850 PATTHSPTPPSPKGAPTP---SAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906
Query: 264 PPPPPPPVGNRPSIHREAVPPPP-----PQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP 318
P + P R A P P P P P P + P P P P P
Sbjct: 907 QAPALSMTSSSPKKAR-ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
Query: 319 PPL-PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP----LPPPPSERPPPPVRD-- 371
P PPS G TP P+ + ++TPP P G + P P PP+ PP P
Sbjct: 966 PAATPPSPKGGPATPS-PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 372 ----PPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGA 427
P G S P PP + + LP + + SP+ GP P P+ A
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084
Query: 428 PPPPPP 433
PP P
Sbjct: 1085 ATPPSP 1090
Score = 74.7 bits (182), Expect = 2e-13
Identities = 109/418 (26%), Positives = 142/418 (33%), Gaps = 81/418 (19%)
Query: 128 LLPPGGRSTSAKPFSPPSG--PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI-- 183
+L P + P PP+G PG V H S + P D G+ +
Sbjct: 725 VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
Query: 184 ---------PPPV-----PSTPRPIQSSPHNRGS--PPVPGGPRQPSPGPTPPPFPGNRG 227
P P+ P T RP P +GS P P G P F
Sbjct: 785 GTLTYLADSPSPLGVSVSPQTKRP----PTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
Query: 228 TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP-----PP---PPPPVGNRPSIHR 279
+ G + SP ++ SP P PTPS P PP P P V N P +
Sbjct: 841 LSFQGS--KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP-FPK 897
Query: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP--PLPPSSSGNDETPRLPQR 337
E P P+ ++ P + P P P+ P P P PP++ TP P+
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA-----TPPSPKG 952
Query: 338 NLSLSSSTPPLPSPGRSGPLPP---PPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394
P PSP + P PP PPS + P P G P PP + G
Sbjct: 953 G-------PATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG----- 999
Query: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRPSA-----GAPPPP---PPSTSIRNGFQDSPC 446
P PS G +P PP P P+A GA PP PPS + SP
Sbjct: 1000 ----PATPSPKGAPTP-PAVTPPSPKGSPAATPFPKGASTPPAATPPSP------KGSPA 1048
Query: 447 EDEWESRFYFHPISDLPPPE--PYVQTTKSYPSKLARN--ESRSGSNRRERGAPPLPP 500
P + LP P+ P + K P+ A + G P+PP
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106
Score = 73.6 bits (179), Expect = 4e-13
Identities = 109/457 (23%), Positives = 159/457 (34%), Gaps = 115/457 (25%)
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGR--------FPVPSPGHRSGPPEPQR------N 167
G PP + P + +P GP P +P PP P++
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490
Query: 168 RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG------------PRQ--- 212
+ P P P ++P +PS+P+ + ++P +R P P P++
Sbjct: 1491 KKAPATPAPMGAP-TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549
Query: 213 ------PSPGPTPP-PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265
PSP TP P P +++P + SS ++ PP TPS K
Sbjct: 1550 PPAMTVPSPKKTPAIPTP------------KEAPATPSSKEASSPPAV-TPSTY---KGA 1593
Query: 266 PPP-----PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPP 320
P P PP PS PP + P+TP P + +PP P + P
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS--P 1651
Query: 321 LPPSSSGNDETPRLPQRNLSLSS-----------------STPPLPSPGRSGPLPPPPSE 363
P+S +PQ + L + STP + +P R GP S
Sbjct: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSA 1711
Query: 364 RPPPPVRDPP---GRSGPL---PPPP--PVSRN------GSTSRALPATPQLPSRSGVDS 409
PP DP G GPL P P PV ++ G + P P P S +
Sbjct: 1712 TSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST 1771
Query: 410 PRSGP--RPPLP-PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPE 466
P + LP P+ S A P PP S + P+ LPP +
Sbjct: 1772 PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS-----------------PVPTLPPKQ 1814
Query: 467 PYVQTTKSYPSKLARNESRSGSNRRERGAPPL-PPIP 502
++ S P + + S+ + E PL PP P
Sbjct: 1815 QFL---PSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848
Score = 50.8 bits (120), Expect = 3e-06
Identities = 77/327 (23%), Positives = 114/327 (34%), Gaps = 49/327 (14%)
Query: 128 LLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPP-----RPDVGSKPDS 182
L+PP TS P P+ P P PSP P P+ PP D + P S
Sbjct: 1600 LIPPA--VTSPSPKEAPTPPAVTP-PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656
Query: 183 IPPPVPST-PRPIQSSPHNRGSPPVPGGPRQPSPGPTPP-PFPGNRGTALGGGSIRQSPL 240
+ + +T P+ + P +G + P+P TP P +G S P+
Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI 1716
Query: 241 --------SSSSPFSNRPPLPPTPSRALDDK-------------PPPPPPPVGNRP--SI 277
S P S P P P + K P PP + P +
Sbjct: 1717 CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAA 1776
Query: 278 HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP------PSRPG----PPPLPPSSSG 327
E V P P + PS P + +P P P PS PG P P + +
Sbjct: 1777 AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPAD 1836
Query: 328 NDE-TPRLPQRNLS----LSSSTPPLPSPGRSG-PLPPPPSERPPPPVRDPPGRSGPLPP 381
DE P +P +S S +P+P +G P+P P +++P G
Sbjct: 1837 EDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDE 1896
Query: 382 PPPVSRNGSTSRALPATPQLPSRSGVD 408
P +++A QL + + +D
Sbjct: 1897 SVPELEEQDSTQATTQQAQLAAAAEID 1923
Score = 42.4 bits (98), Expect = 0.001
Identities = 73/304 (24%), Positives = 102/304 (33%), Gaps = 65/304 (21%)
Query: 147 PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV 206
PG P P+PQ P S ++ P P+ P P +P
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 207 PGGPRQPSPG-----PTPPPFP-GNRGTALGGGSIRQSP---------------LSSSSP 245
PSP P PFP + GTAL G+ ++P L+ +SP
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 246 FSNRPPLPPTPSRAL---------------DDKPP-----PPPPPVGNRPSIHREAVP-- 283
P L TPS + PP PP V S+ + P
Sbjct: 122 MI-APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180
Query: 284 PPPPQNNKPPVPSTPRPSASSQAPPP------------PPPPSRPGPPPLP---PSSSGN 328
P P+ N VPS P+ PP P + G LP P+++
Sbjct: 181 PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA 240
Query: 329 DETPRLPQRNLSLSSSTPPLP-SPGRSGPLPPPP----SERPPPPVRDPPGRSGPLPPPP 383
+P++ +S +P P S GP+ PP S + P V +GP PP
Sbjct: 241 IASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300
Query: 384 -PVS 386
P+S
Sbjct: 301 FPIS 304
Score = 32.7 bits (73), Expect = 0.79
Identities = 81/367 (22%), Positives = 121/367 (32%), Gaps = 52/367 (14%)
Query: 93 GGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP---------LLPPGGRSTSAKPFSP 143
G PP L +P + S+ +G + PP L P S +
Sbjct: 268 GPVSPPAALSLSTQSLPVVTSS---QKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLG 324
Query: 144 PSGPGRFPVP-----SPGHRS-GPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSS 197
+GP P S H S G P + + PP P S+ + +P V + P
Sbjct: 325 QTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLP---SRNEVVPATVAAFPVV---- 377
Query: 198 PHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP---P 254
+P V GP S P N T+ L SS + PL P
Sbjct: 378 -----APSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMP 432
Query: 255 TPSRALDDKPPPPPPPVGNRPSIHRE-AVPPPPPQNNKPPVPSTPR-PSASSQAPPPPPP 312
S P + P+ E A PP ++ P P P+A AP P
Sbjct: 433 VSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKE 492
Query: 313 PSR--------PGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS-PGRSGPLPPPPSE 363
PS P PPLP ++ LP L + L + P P P++
Sbjct: 493 PSTQVATTLRIPVSPPLPDP----EDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQ 548
Query: 364 RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP 423
+DP LP +N + ++ ++P++P + PLP +P
Sbjct: 549 AGLTTKKDPT----VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP 604
Query: 424 SAGAPPP 430
++ P
Sbjct: 605 ASSMTSP 611
Score = 32.7 bits (73), Expect = 0.79
Identities = 71/295 (24%), Positives = 103/295 (34%), Gaps = 46/295 (15%)
Query: 91 SFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP---LLPPGGRSTSAKPFSPPSGP 147
SFG G G P +++ + + +G S P ++PP ++ P+
Sbjct: 316 SFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPP----LPSRNEVVPATV 371
Query: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP 207
FPV +P GP P + S+ P +T ++SSP+ P+
Sbjct: 372 AAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSP---TTSLILKSSPNATYHYPLV 428
Query: 208 GGPRQPSPGPTP-----PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262
S G TP P T + SP SS P SN + PT AL
Sbjct: 429 AQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISN---IEPTSPAALVM 485
Query: 263 KPPPPPPPVGNRPSIHREAVPPP------------------PPQNNKPPVPSTPR--PSA 302
P P P + R V PP P Q + VP++ P +
Sbjct: 486 APVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS 545
Query: 303 SSQA------PPPPPPPSRPGPPPLPP--SSSGNDETPRLPQRNLSLSSSTPPLP 349
+QA P P + P P S+S + E P P+ L+ S PLP
Sbjct: 546 PAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLP 600
Score = 31.2 bits (69), Expect = 2.3
Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 6/122 (4%)
Query: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPP-PPPSRPGPPPLPPSSSGNDETPRLPQRN 338
+ +P P + P+ S +A+ P P PPP P P P S++ P +
Sbjct: 14 QELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS----PFPS 69
Query: 339 LSLSSSTP-PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
S +STP +P P S P P P P P+ P + + L
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
Query: 398 TP 399
TP
Sbjct: 130 TP 131
Score = 30.4 bits (67), Expect = 3.9
Identities = 34/132 (25%), Positives = 46/132 (34%), Gaps = 18/132 (13%)
Query: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS--- 376
PL P++S N PQ + ++ P +S P P P PP + G S
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758
Query: 377 --GPLPPPP---PVSRNGSTSRA-----LPATPQLPSRSGVDSPRSGPRPPLP-----PD 421
P+ P P +G+++ A L PS GV RPP PD
Sbjct: 759 ALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
Query: 422 RPSAGAPPPPPP 433
P P P
Sbjct: 819 TPIGNLSSPVSP 830
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 115 bits (287), Expect = 1e-25
Identities = 117/382 (30%), Positives = 155/382 (40%), Gaps = 79/382 (20%)
Query: 115 ANRDNDSGGSRPPLLPPGGRS--TSAKPFSPP--SGPGRFPVP-SPGHRSGPPEP--QRN 167
A R +GG L P RS +SA P S P SGP P +P H S P Q
Sbjct: 224 ARRRPSAGGG---LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
Query: 168 RMP---PPRPD-------VGSKPDSIPPPVPS----TPRPIQSSPHNRG----------- 202
R P PPR D + S P + P P + P + ++PH+
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
Query: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262
+PP P P P+PP P ++ T S+ L ++ F PPL P +
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATT----SLGSPTLQATHSFLPSPPLSPLAT----- 391
Query: 263 KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS----QAP--PPPPPP--- 313
PPP PP P + PP P + PS P+A + QAP PPP PP
Sbjct: 392 -PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 314 --SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL---PSPGRSGPLPPP--PSERPP 366
S P PP+ PS++ + P S + PPL PSP S P+ P P + P
Sbjct: 451 PFSPPASPPVSPSATPPSQAPP--------SLAAPPLQVPPSPPASPPMSPSATPPPQAP 502
Query: 367 PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ--------LPSRSGVDSPRSGPRPPL 418
PP+ PP + PP P + +ALP+ P PS S SP + P P
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562
Query: 419 PP--DRPSAGAPPPPPPSTSIR 438
PP P PP PP S +++
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQ 584
Score = 102 bits (255), Expect = 6e-22
Identities = 114/386 (29%), Positives = 138/386 (35%), Gaps = 51/386 (13%)
Query: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGS--KPDSI 183
P L P ++ + P SPP P P P + Q PPP P V + P +
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 184 PPPVPSTPRPIQSSPHNRGSPPV---PGGPRQP--SPGPTPPPFPGNRGTALGGGSIRQS 238
PP PS P Q+ P + +PP+ P P P SP TPPP Q+
Sbjct: 458 PPVSPSATPPSQAPP-SLAAPPLQVPPSPPASPPMSPSATPPP---------------QA 501
Query: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP 298
P PPL P + KPPP PP P + PP P PS
Sbjct: 502 P----------PPLAAPPLQLA--KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549
Query: 299 RPSASSQAPPPPPPPSRPGP----PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354
P + PPP PP P PP PP+S R P S S P L
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609
Query: 355 GPLPPPPSERPPPPVRDP--PGRSGPLPPPPPVSR--NGSTSRALPATPQLPSRSGVDSP 410
GP PPPPS P + P G S P R + A+P + P
Sbjct: 610 GP-PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 668
Query: 411 RSGPRPPLPP--DRPSAGAPPPPPPSTSIRNGFQDSPC---EDEWESRFYFHPISDLPPP 465
+ R P PP R + GAP P PP+T G D C E E P + P P
Sbjct: 669 AAWSRGPAPPLAFRGAPGAPLPWPPATG--PGSADGLCTIYETEGPESATPAPGALDPGP 726
Query: 466 EPYVQTTKSYPSKLARNESRSGSNRR 491
P K+ A SRS R
Sbjct: 727 SPGTSGGKAAAGAGAGASSRSPKQAR 752
Score = 96.7 bits (239), Expect = 4e-20
Identities = 125/447 (27%), Positives = 157/447 (35%), Gaps = 103/447 (23%)
Query: 70 GGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLL 129
G G G GG GG + P +AG + T++R+ SRPP
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAP-------RAGPTRSAGTSSRNP---ASRPPAS 97
Query: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQ------------------RNRMPP 171
G R+ AK SP PV SPG SG P + P
Sbjct: 98 GRGERAPPAKNTSPG------PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 151
Query: 172 PRP--DVGSKPDSIPP----PVPSTPRPIQSSPHNRGSP-PVPGG-PRQPSPGP------ 217
R G++ D+ P P P+ R +++ G P P P PR P+ GP
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211
Query: 218 ------TPPPFPGNRGTALGGG-------SIRQSPLSSSSPFSNRPPLPPTPSRALDDKP 264
T P R + GGG S+ S SSP + P TP
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
Query: 265 PPPP------PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP------ 312
P P PP P ++A P P ++ P +P + SQAPP P
Sbjct: 272 PKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
Query: 313 ---------PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP-------LPSPGRSGP 356
P P P PPS P P + S +P LPSP S P
Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS-P 388
Query: 357 LPPPPSERPP----PPVRDPPG--RSGPLPP---PPPVSRNGSTSRALPATPQLPSRSGV 407
L PP + PP PP++ PP S PL P P P + N L A P V
Sbjct: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 448
Query: 408 DSPRSGPRPPLPPDRPSAGAPPPPPPS 434
+P S P PP PSA P PPS
Sbjct: 449 QAPFSPPAS--PPVSPSATPPSQAPPS 473
Score = 84.3 bits (207), Expect = 2e-16
Identities = 130/462 (28%), Positives = 163/462 (35%), Gaps = 73/462 (15%)
Query: 97 PPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPG 156
P L L AG + A R GG+ P P T + S + R P G
Sbjct: 41 PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG 100
Query: 157 HRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN---RGS-------PPV 206
R+ P +N P P G + P P + ++ S RG +
Sbjct: 101 ERA---PPAKNTSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 156
Query: 207 PGGPRQPSPGP---TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP---PTPSRAL 260
G R+ + GP TP P R A G P S+ P RPP + S A
Sbjct: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSSAS 213
Query: 261 DDKPPPPPPPVGNRP------------SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
+ P P RP S+ A P P + P TPR A P
Sbjct: 214 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273
Query: 309 P-------PP---PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP-LPSPGRSG-- 355
P PP PP + P L P SS T P + +L S PP LP+ S
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT---PSPSAALQSQAPPTLPATPHSSSL 330
Query: 356 ------PLP-PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ-LPSRSGV 407
PLP PPS PP ++ P P PP + S L AT LPS
Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLP---SPPATPPSQATTSLGSPTLQATHSFLPSPP-- 385
Query: 408 DSPRSGPRPPLPP--DRPSAGAPPPPPPSTSIRNGFQDSP-CEDEWESRFYFHPISDLPP 464
SP + P P PP P APP PP S + SP + P S PP
Sbjct: 386 LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS--PP 443
Query: 465 PEPYVQTTKSYPSKLARNESRSGSNRR--ERGAPPL--PPIP 502
P P VQ S P+ + S + ++ APPL PP P
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485
Score = 74.3 bits (181), Expect = 2e-13
Identities = 107/409 (26%), Positives = 139/409 (33%), Gaps = 132/409 (32%)
Query: 210 PRQP-SPGPTPPPFP-----------------GNRGTALGGGSI----------RQSPLS 241
PR P SP P PP P R +GG +I R + S
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86
Query: 242 SSSPFSNRPP-------LPP----------TPSRALDDKPPPPPPPVGNRPSIH------ 278
S +P ++RPP PP +P RA P P G R S
Sbjct: 87 SRNP-ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 145
Query: 279 -------REAVPPPPPQNNKPPVPSTPRPSASSQAP--------PPPPPPSRPGPP---- 319
R A+ ++ P P TP P+ + ++ P P P +RP PP
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
Query: 320 --------------PLP-----PSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP---- 356
P P PS+ G + P + SLSSS PL SP RSGP
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRP----ASRSLSSSATPLSSPARSGPSARG 261
Query: 357 ---LPPPPSE---------RPP---PPVRDPPGRSGPL------PPPPPVSRNGSTSRAL 395
P PS+ RPP PP +D GPL P P + L
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321
Query: 396 PATP---QLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
PATP L + P + P P PP + +PP PPS + + SP S
Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS--LGSPTLQATHS 379
Query: 453 RFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPI 501
P+S L P P + P A + +PPL P+
Sbjct: 380 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA--------SPPLSPL 420
Score = 29.6 bits (65), Expect = 6.7
Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 8/90 (8%)
Query: 2 PVPPPPAP------PPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRS 55
P PAP P P T + ++ + A L ++ G V + S
Sbjct: 712 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLS 771
Query: 56 APILDKPKGAGAGGGGGGFGG--GGGFGGG 83
+L AGG GGG GG GGG GG
Sbjct: 772 RTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 801
Score = 29.3 bits (64), Expect = 8.7
Identities = 14/25 (56%), Positives = 14/25 (56%)
Query: 65 AGAGGGGGGFGGGGGFGGGGGGGGG 89
A A G GG GGG G GGG GG
Sbjct: 777 AAAEGAAGGSGGGPGGAEGGGVTGG 801
Score = 29.3 bits (64), Expect = 8.7
Identities = 13/26 (50%), Positives = 13/26 (50%)
Query: 75 GGGGGFGGGGGGGGGGSFGGGGPPGL 100
G GG GGG GG GG GG L
Sbjct: 781 GAAGGSGGGPGGAEGGGVTGGARAAL 806
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 114 bits (286), Expect = 2e-25
Identities = 114/385 (29%), Positives = 145/385 (37%), Gaps = 71/385 (18%)
Query: 127 PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPP 186
PLLPP S P SPP P SP + PP P+ +R+ PP ++ + P P
Sbjct: 439 PLLPPPEES----PLSPP------PEESP---TSPP-PEASRLSPPPEELPASP---LPE 481
Query: 187 VPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPF 246
RP++ SP SPP P P P +P + +SPLS
Sbjct: 482 ALHLSRPLEESPL---SPPPEESPLSPPPESSP------------FSPLEESPLS----- 521
Query: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
PP PS AL+ PPP P + PPP + +P++P P AS +
Sbjct: 522 ---PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE-----LPTSPPPEASRLS 573
Query: 307 PPPPPPPSRPGPP--PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER 364
PPP P P P P+ P + P + LS PL P + L PPP +
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633
Query: 365 P--PPPVRDP---PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLP 419
P PPP P P L P P VSR P +P P S P R P
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP-PEESPTSPPPEASRLSPP 692
Query: 420 PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLP----PPEPYVQTTKSY 475
P+ +P PPP +DSP E P+ + P P EP +
Sbjct: 693 PE----DSPTSPPP--------EDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740
Query: 476 PSKLARNESRSGSNRRERGAPPLPP 500
P R E S R E P L P
Sbjct: 741 PHLSPRPEEPHLSPRPEE--PHLSP 763
Score = 94.7 bits (234), Expect = 2e-19
Identities = 119/392 (30%), Positives = 142/392 (36%), Gaps = 61/392 (15%)
Query: 127 PLLPPGGRSTSAKPF-----SPPSGPGRFPVPSP--GHRSGPPEPQRNRMPPPRPDVGSK 179
PL PP S + PF SPP P P P R PP + PPP S
Sbjct: 535 PLSPPPEASPLSPPFEESPLSPP--PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592
Query: 180 P---DSIPPPVPSTP--RPIQSSP------HNRGSPPVPGGPRQPSP--GPTPPPFPGNR 226
P + PP +P P + SP +R SPP P P P P PP +R
Sbjct: 593 PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Query: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPT--PSRALDDKPPPPPPPVGNRPSIHREAVPP 284
+ L S R SP SP S P PT P A PPP P P A PP
Sbjct: 653 LSPLPVVS-RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPE-DSPASPP 710
Query: 285 PP------PQNNKP--PVPSTPRPSASSQAPPPPPPPSRP--GPPPLPPSSSGNDETPRL 334
P P P P+P P+ S+ P P P P P P P S E P L
Sbjct: 711 PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL 770
Query: 335 -PQRNLSLSSSTPPLP--SPGRSGP-LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
PQ + P P SP GP L P P E P + P S P+P P +S
Sbjct: 771 SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS-PVPEEPCLSPQPE 829
Query: 391 TSRALPAT--PQLPSR-------SGVDSPRSGPRPPLPPDRPSAGAPP------PPPPST 435
S P + P L R ++ P PRP PP+ P P PPP
Sbjct: 830 ESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEP 889
Query: 436 SIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
S+ + + E P+S LP P
Sbjct: 890 SLSPLLGEPALSEPGEP-----PLSPLPEELP 916
Score = 90.5 bits (223), Expect = 3e-18
Identities = 110/418 (26%), Positives = 138/418 (33%), Gaps = 66/418 (15%)
Query: 127 PLLPPGGRSTSAK---PFSPPSGPGRFPVPSPGHRSG---PPEPQRNRMPPPRPDVGSKP 180
PL PP S P SPP P P+ P S PPE PP + P
Sbjct: 519 PLSPPEESPPSPALETPLSPP--PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576
Query: 181 DSIPPPVPSTPRPIQSSPH-NRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSP 239
+ P P P+ P +R PP P P P +P P + R SP
Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE--------ASRLSP 628
Query: 240 LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP--VPST 297
SP S PP +P PPP + P + R + PP + PP P++
Sbjct: 629 PPEDSPMS--PPPEESPM-----SPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681
Query: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP-QRNLSLSSSTPPLPSPGRSGP 356
P P AS +PPP P+ P P P S D LP + + L P P GP
Sbjct: 682 PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP 741
Query: 357 -LPPPPSE-----RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS-GVDS 409
L P P E RP P P L P P L A P+ P S +
Sbjct: 742 HLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP-------EEPCLCAVPEEPHLSPQAEG 794
Query: 410 PRSGPRPP---LPPDRPSAGAPP-------PPPPSTSIRNGFQDSPCEDEWESRFYFHPI 459
P P+P L P P P P S + + PC + P
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
Query: 460 SDLPPPEPYVQTTKSYPSKLARNES---------------RSGSNRRERGAPPLPPIP 502
+ PP P + P + E E G PPL P+P
Sbjct: 855 LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP 912
Score = 78.6 bits (192), Expect = 1e-14
Identities = 79/282 (28%), Positives = 103/282 (36%), Gaps = 62/282 (21%)
Query: 213 PSPGPTPPPFPGN-----RGTALGGGSIRQSPLSSSSPFSNRPPL-------PPTPSRAL 260
P PG TP P +G GG P PL P L
Sbjct: 375 PEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPL 434
Query: 261 DDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPP 320
+++ P PPP E+ PPP+ + P++P P AS +PPP P+ P P
Sbjct: 435 NEEMPLLPPP--------EESPLSPPPEES----PTSPPPEASRLSPPPEELPASPLPEA 482
Query: 321 LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP---------PPPVRD 371
L +LS PL P PL PPP P PP
Sbjct: 483 L----------------HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 372 PPGRS--GPLPPPP---PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAG 426
PP + PL PPP P+S S P +LP+ ++ R P P P P
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586
Query: 427 APP--PPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPE 466
P PPP ++ + F++SP E P+S PPPE
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEE----SPLS--PPPE 622
Score = 78.6 bits (192), Expect = 1e-14
Identities = 101/344 (29%), Positives = 126/344 (36%), Gaps = 52/344 (15%)
Query: 127 PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP- 185
PL PP S P SPP R P + PP PPP + S P P
Sbjct: 670 PLSPPPEES----PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725
Query: 186 -PVPSTPR--PIQSSPHNRGSPPVPG-GPRQPSPGPTP---PPFPGNRGTALGGGSIRQS 238
P+P P+ P PH P P PR P +P P + ++ +
Sbjct: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785
Query: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPP---PVGNRPSIHREAVPPP-----PPQNN 290
P SP + P L P P L P P PV P + P P PQ+
Sbjct: 786 P--HLSPQAEGPHLSPQPEE-LHLSPQTEEPHLSPVPEEPCLS----PQPEESHLSPQSE 838
Query: 291 KPPVPSTPRPSASSQAP---PPPPPPSRPGPPPLPPSSSGNDETPRLP---QRNLSLSSS 344
+P + +PRP S +P PP P PP P +E P P + +LS
Sbjct: 839 EPCL--SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG 896
Query: 345 TPPLPSPGRSGPLPPPPSERPPPPVRDP---PGRSGPLPPPPPVSRNGSTSRALPATPQL 401
P L PG PL P P E P P +P P P P PPP+S T+ A PA L
Sbjct: 897 EPALSEPGEP-PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPI-ITAAAPPALSPL 954
Query: 402 ---------PSRSGVDSPRSGP---RPPLPPDRPSAGAPPPPPP 433
S +SP + P P PP + P P PP
Sbjct: 955 GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPP 998
Score = 73.2 bits (178), Expect = 5e-13
Identities = 101/387 (26%), Positives = 134/387 (34%), Gaps = 65/387 (16%)
Query: 84 GGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSP 143
G GGG S PP G ++ + + G S P PP SP
Sbjct: 2262 GVGGGKASEPLLSPPPFG-------ESRKALEVKKEELGASSPSYGPPNLGFVD----SP 2310
Query: 144 PSGP--GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNR 201
SG G + +P P P+ +++ P P +G +P PP P P R
Sbjct: 2311 SSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFR 2370
Query: 202 -GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRAL 260
GS P QP P P P P AL S+ S PFS P P + S +
Sbjct: 2371 PGSYTDPYA--QPPLTPRPQPPPPESCCALPPRSL------PSDPFSRVPASPQSQSSSQ 2422
Query: 261 DDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS---RPG 317
P P PS P P + P P + P A PP P PP + G
Sbjct: 2423 SPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAG 2482
Query: 318 ------------PPPLPPSSSGNDETPRLPQRNLSLSSSTPP--LPSPGRSGPLPPP--- 360
P LP +G + + + S PP + SPG + P
Sbjct: 2483 SLAHTSLGAGGFPAALPAGPAG--------ELHAKVPSGQPPNFVRSPGTGAFVGTPSPM 2534
Query: 361 ----------PSERPP---PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS-- 405
PS +PP P + P G + P P + + ST+ + PS S
Sbjct: 2535 RFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPL 2594
Query: 406 GVDSPRSGPRPPLPPDRPSAGAPPPPP 432
G S +G L P RP + PPP P
Sbjct: 2595 GPSSGSTGESYGLSPLRPPSVLPPPAP 2621
Score = 72.8 bits (177), Expect = 7e-13
Identities = 112/379 (29%), Positives = 135/379 (35%), Gaps = 54/379 (14%)
Query: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRF-PVPSPGHRSGPPEP--------QRNRMPPPRP 174
S PP P P SPP R P+P S PPE + PPP
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEA 686
Query: 175 D-VGSKPDSIPPPVPSTPRPIQSSPHNR-GSPPVPGGPRQPSPGPTPPPFPGNRGTALGG 232
+ P+ P P P P + S P+ P P P P P + G L
Sbjct: 687 SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP-EEPQLCPRSEGPHL-- 743
Query: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPP---PQN 289
SP S RP P +A + P P P + AVP P PQ
Sbjct: 744 -----SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP----EEPCLC--AVPEEPHLSPQA 792
Query: 290 NKP---PVPSTPRPSASSQAPPPPPPPSRP--GPPP----LPPSSSGNDETPRLPQRNLS 340
P P P S ++ P P P P P P L P S +PR + +LS
Sbjct: 793 EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLS 852
Query: 341 LSSSTPPLPSPGRSGPLPPPPSERPPP---PVRDPPGRS--GPLPPPPPVSRNGSTSRA- 394
PPL SP P P P + P P P+ PPG PL P +S G +
Sbjct: 853 PELEKPPL-SPRPEKP-PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP 910
Query: 395 LP-ATPQLPSRSGVDSPRSGPRPPLPPDRP---SAGAPPPPPPSTSIRNGF---QDSPCE 447
LP P PS SP+ P PLPP +A APP P + F DS E
Sbjct: 911 LPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPE 970
Query: 448 DEWESRFYFHPISDLPPPE 466
+ PIS PPPE
Sbjct: 971 SPLAAPILETPIS--PPPE 987
Score = 57.0 bits (136), Expect = 4e-08
Identities = 94/370 (25%), Positives = 119/370 (32%), Gaps = 80/370 (21%)
Query: 168 RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRG 227
R+PP +GS P + P + GSP P G + G PP
Sbjct: 2105 RIPPQPGALGSPPPAAAPTIFI------------GSPTTPAGLSTSADGFLKPP------ 2146
Query: 228 TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP 287
GS+ P S F PP P P P G P+ E P P
Sbjct: 2147 ----AGSV-PGPDSPGELFLKLPPQVPA--------QVPSQDPFGLAPAYPLEPRFPTAP 2193
Query: 288 QNNKPPVPSTPRPSASSQAPPPPPPPSRPG---------PPPLPPSSSGNDETPRLPQRN 338
P P P P+ + PP SRPG PP P + P L R
Sbjct: 2194 ----PTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC 2249
Query: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPP---------PVRDPPGRSGPLPPPPPVSRNG 389
SL + P SPG G P PPP ++ G S P PP +
Sbjct: 2250 PSLDNLAVP-ESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVD 2308
Query: 390 STSRA---------------LPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
S S P TP+ S+ SP G RP PP A AP PP
Sbjct: 2309 SPSSGTHLGGLELKTPDVFKAPLTPR-ASQVEPQSPGLGLRPQEPPP-AQALAPSPPSHP 2366
Query: 435 TSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNE-SRSGSNRRER 493
R G P + P++ P P P P L + SR ++ + +
Sbjct: 2367 DIFRPGSYTDP--------YAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQ 2418
Query: 494 GAPPLPPIPR 503
+ P PR
Sbjct: 2419 SSSQSPLTPR 2428
Score = 56.6 bits (135), Expect = 5e-08
Identities = 92/364 (25%), Positives = 118/364 (32%), Gaps = 85/364 (23%)
Query: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPR----QPSPGPTP------PPF--PGNRGTAL- 230
P + +TP + + P P + G + QP P P P PP PG + +
Sbjct: 4048 PLAIGTTPESMATEP-GEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVS 4106
Query: 231 -----GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP-------PPPPVGNRPSIH 278
GGGS Q SSS S+ P L PS +L D+P P P+ RP +
Sbjct: 4107 LLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQN 4166
Query: 279 REAVPPPPPQ------NNKPPVPSTP---------------------------------- 298
PP P P V P
Sbjct: 4167 NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALL 4226
Query: 299 --RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
R SQA PP PG P + PQ T PL G +GP
Sbjct: 4227 MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQ----PQLGGFPGPQTGPLQELG-AGP 4281
Query: 357 LPPPPSERPPPPVRDPPGRS-GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR 415
P P P PP G GP+ P PP S P P+ PS+ S +
Sbjct: 4282 RPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS--------PQEPKRPSQLPSPSSQLPTE 4333
Query: 416 PPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSY 475
LPP P G P P P+ G + SP + + + PP+ +T K
Sbjct: 4334 AQLPPTHP--GTPKPQGPTLEPPPG-RVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE 4390
Query: 476 PSKL 479
S L
Sbjct: 4391 QSSL 4394
Score = 55.1 bits (131), Expect = 1e-07
Identities = 70/282 (24%), Positives = 93/282 (32%), Gaps = 41/282 (14%)
Query: 125 RPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP 184
+PPL PG + G + S P + + P +G +P S+
Sbjct: 4092 QPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVP--HLLAQPSVSLGDQPGSMT 4149
Query: 185 -----PPVPSTPRPIQSSPHNRGSPPVPGGP----RQPSPGPTPPPFPGNRGTALGGGSI 235
P P RP+Q+ N G P GP Q PG P G L G
Sbjct: 4150 QNLLGPQQPMLERPMQN---NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA 4206
Query: 236 RQSPLSSSSPFSNRP------PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQN 289
+ L SP + S+A+ PP P P + + PQ
Sbjct: 4207 KNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPL---QGLLGCQPQL 4263
Query: 290 NKPPVPSTPRPSASSQAPPPPPPPSRPGPP-------------PLPPSSSGNDETPRLPQ 336
P P T P P PP P PP P PP SS P+ P+
Sbjct: 4264 GGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS-----PQEPK 4318
Query: 337 RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGP 378
R L S + LP+ + P P + P + PPGR P
Sbjct: 4319 RPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSP 4360
Score = 47.4 bits (111), Expect = 3e-05
Identities = 53/179 (29%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG--NRGTALGGGSIRQ 237
P+S P +P + P +G PGG + G +P P + A+ G +
Sbjct: 4812 PNSYEVLFPESPARAGTEP-KKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLK 4870
Query: 238 SPLSSSSPFSNRPPLPPTPS-------------RALDDKPP--PPPPPVGNRPSIHREAV 282
S L S P P P+ R L PP P PPP PS A
Sbjct: 4871 SQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS---PAS 4927
Query: 283 PPPPPQNN-------KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
PP P +PPVPS P P ASS P +RP P PP + PRL
Sbjct: 4928 PPTEPLVELPTEPLAEPPVPS-PLPLASS------PESARPKPRARPPEEGEDSRPPRL 4979
Score = 43.5 bits (101), Expect = 4e-04
Identities = 33/109 (30%), Positives = 39/109 (35%), Gaps = 11/109 (10%)
Query: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
S+ ++ P P P + + PPP PS P P PL PS P P
Sbjct: 4877 SLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPP-PSPLAPS-------PASP 4928
Query: 336 QRNLSLSSSTPPLPSPGRSGPLP---PPPSERPPPPVRDPPGRSGPLPP 381
+ T PL P PLP P S RP P R P PP
Sbjct: 4929 PTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 43.1 bits (100), Expect = 6e-04
Identities = 69/296 (23%), Positives = 92/296 (31%), Gaps = 46/296 (15%)
Query: 97 PPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPG 156
PP L L + P + + D +S + P L P A P P PSPG
Sbjct: 948 PPALSPLGELEYP-FGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006
Query: 157 HRSGPPEP--------------QRNRMPPPRPDVGSKPDSIPPPVPSTPRPI-------- 194
GP P Q + +P P P ++P VPS PI
Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSD 1066
Query: 195 QSSPHNRGS--------PPVPGGPRQPSPGP-----TPPPFPGNRGTALGGGSIRQSPLS 241
++ H + P + P P P P P P G +PL
Sbjct: 1067 EAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLD 1126
Query: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301
++P TP + G+ + E + P P P T
Sbjct: 1127 GIDAPGSQPEPGQTPGSLASELK-------GSPVLLDPEELAPVTPMEVYPECKQTAGQG 1179
Query: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS--SSTPPLPSPGRSG 355
+ + P P P PP L S N E L Q + S S S P L SP G
Sbjct: 1180 SPCEEQEEPRAPVAPTPPTLIKSDIVN-EISNLSQGDASASFPGSEPLLGSPDPEG 1234
Score = 40.8 bits (94), Expect = 0.003
Identities = 95/343 (27%), Positives = 117/343 (34%), Gaps = 87/343 (25%)
Query: 160 GPPEPQRNRMPPPRP------DVGSKPDSIPPPVPSTPRPIQS---SPHNRGS--PPVPG 208
G P + +R P RP +G+ P S P+ S P QS RG P PG
Sbjct: 1910 GTPGLEGSRTPLQRPFLQGGLPLGNLPSS--SPMDSYPGLCQSPFLDSRERGGFFSPEPG 1967
Query: 209 GPRQPSPG-----PTPPPFPGNRGTALGGGSIRQS-----------PLSSSSP------- 245
P P G P+ P P G G ++S LS+ SP
Sbjct: 1968 EPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANIN 2027
Query: 246 FSN-RPPLPPTPSRALD-----------DKPPPPPPPVGNRPSIHR--EAVPPPPPQNNK 291
F N + P SR DK P NR + HR + Q NK
Sbjct: 2028 FPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAA-HRINKVQKQAESQINK 2086
Query: 292 PP-----VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS-- 344
T RP+ + PP P P P P G+ TP LS S+
Sbjct: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTP----AGLSTSADGF 2142
Query: 345 -TPPLPS-PGRSGP----LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
PP S PG P L PP P +DP G L P P+ T A P
Sbjct: 2143 LKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFG----LAPAYPLEPRFPT--APPTY 2196
Query: 399 PQLPSRSGVDSPRSGPRPPL--PPDRPSAGAP------PPPPP 433
P PS +G + +PP+ RP AG P PP P
Sbjct: 2197 PPYPSPTGAPA-----QPPMLGASSRPGAGQPGEFHTTPPGTP 2234
Score = 38.5 bits (88), Expect = 0.014
Identities = 30/101 (29%), Positives = 38/101 (37%), Gaps = 8/101 (7%)
Query: 318 PPPLPPSS-SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS 376
P P PP+ S L R LS P P P P P P P + P
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 377 GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP 417
P+P P P++ + ++R P P G DS RPP
Sbjct: 4944 PPVPSPLPLASSPESARPKPRA--RPPEEGEDS-----RPP 4977
Score = 34.7 bits (78), Expect = 0.21
Identities = 80/343 (23%), Positives = 110/343 (32%), Gaps = 82/343 (23%)
Query: 85 GGGGGGSFG-----GGGPPGLGGLFQAGMPKLR----------------STANRDNDSGG 123
G G G S G PG+ GL Q + K R +T ++ ++
Sbjct: 2649 GTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAA 2708
Query: 124 SRPPLLPPGGRSTSAKPFSPPS---GPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
+ + P G S A+P SP G+ P +S +++ P GS P
Sbjct: 2709 AAAGAVGPPG-SWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFP 2767
Query: 181 D----SIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTP----------------- 219
S PPP P+TP + + R P PG P
Sbjct: 2768 SDDRLSRPPP-PATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA 2826
Query: 220 --------PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPV 271
FP G LG RQ+ S + S R P P P P P +
Sbjct: 2827 TSMRFAMSARFPSTPGPELG----RQALGSPLAGISTRLPGPGEPVPG----PAGPAQFI 2878
Query: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP------------PSRPGPP 319
R ++ + P P + P P PR S+ P P P +P P
Sbjct: 2879 ELRHNVQKGLGPGGTPFPGQGP-PQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAP 2937
Query: 320 PLPPSSSGNDETPR-----LPQRNLSLSSSTPPLPSPGRSGPL 357
P P ++ TP LP L L + P GR PL
Sbjct: 2938 PAPELNNSLHPTPHTKGPTLP-TGLELVNRPPSSTELGRPNPL 2979
Score = 34.3 bits (77), Expect = 0.27
Identities = 51/191 (26%), Positives = 64/191 (33%), Gaps = 58/191 (30%)
Query: 149 RFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQ--SSPHNRGSPPV 206
RFP +PG PE R + P + ++ PVP P Q HN
Sbjct: 2836 RFP-STPG-----PELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLG 2889
Query: 207 PGGPRQPSPGPTPPP--FP-----------GNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253
PGG P GP P +P G RG A+ G LP
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSG-------------------LP 2930
Query: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS----TPRPSASSQAPPP 309
P KP PP P N S+H P P P +P+ RP +S++ P
Sbjct: 2931 P-------QKPSAPPAPELNN-SLH------PTPHTKGPTLPTGLELVNRPPSSTELGRP 2976
Query: 310 PPPPSRPGPPP 320
P G P
Sbjct: 2977 NPLALEAGKLP 2987
Score = 34.3 bits (77), Expect = 0.27
Identities = 38/159 (23%), Positives = 51/159 (32%), Gaps = 43/159 (27%)
Query: 131 PGGRSTSAKPFSPPSGPG---RFPVPSPGHRSGPP----EPQRNRMPPPRP--------- 174
PGG+ + SP +GP +F PG+ + P P P
Sbjct: 4838 PGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYN 4897
Query: 175 -------DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRG 227
+ + P P P PS P +SP +P P P P+P P
Sbjct: 4898 VSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPL----- 4952
Query: 228 TALGGGSIRQSPLSSSSPFSNRP-PLPPTPSRALDDKPP 265
+SSP S RP P P D +PP
Sbjct: 4953 --------------ASSPESARPKPRARPPEEGEDSRPP 4977
Score = 33.9 bits (76), Expect = 0.35
Identities = 48/197 (24%), Positives = 61/197 (30%), Gaps = 23/197 (11%)
Query: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279
P F A G G + L +S + P + SR L+ K P P G
Sbjct: 1797 PSFGLGTPKAKGDGGSERKELPTSQKGDDGPDIADEESRGLEGKADTPGPEDGG------ 1850
Query: 280 EAVPPPPPQNNKPPVPSTPRPSASSQ--APPPPPPPSRPGPPPLPPSSSGNDETPRLPQR 337
P P KP P S+ + P L G++ L
Sbjct: 1851 VKASPVPSDPEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCG 1910
Query: 338 NLSLSSSTPPLPSPGRSG--PLPPPPSERP--------PPPVRDPPGRSGPLPPPP---- 383
L S PL P G PL PS P P D R G P P
Sbjct: 1911 TPGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPD 1970
Query: 384 -PVSRNGSTSRALPATP 399
P + +G T+ + P TP
Sbjct: 1971 SPWTGSGGTTPSTPTTP 1987
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 114 bits (284), Expect = 3e-25
Identities = 143/513 (27%), Positives = 183/513 (35%), Gaps = 126/513 (24%)
Query: 2 PVPPPPAPPPPPT------------------FALANTEKPTLNKT--------------E 29
PVPP P+P P P A E N+ E
Sbjct: 1206 PVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDE 1265
Query: 30 QAGRNALLSDISKGKKLKKTVTNDR---SAPILDKPKGAGAGGGGGGFGGGG-GFGGGGG 85
G L + + G +L+ + + D SA + + AG+G G GG+G G +GGGGG
Sbjct: 1266 DGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGG 1325
Query: 86 GGGGGSFGGGGP---PGLGGLFQAGMP-----KLRSTANRDNDSGGSRPPLLPPGGRSTS 137
SF P P G P R A +++ GG P
Sbjct: 1326 SSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQ---------- 1375
Query: 138 AKPFSPPSGPGRFPVPSPGHRS--------------GPPEPQRNRMPPPRPDVGSKPDSI 183
P PPS P P+P H S PP+P R + R +GS+ S+
Sbjct: 1376 -PPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGY-RAGLGSQEKSL 1433
Query: 184 PPPVPSTPRPIQSSPHNRGSPPVPG-GPRQPSPGPTPP-PFPGNRGTALGGGSIRQSPLS 241
P P+ R + +R P PG GP G PP P PG P
Sbjct: 1434 PASPPAARRSLL----HRLPPTAPGVGPLLLQLGTEPPAPHPGV-----------SKPWR 1478
Query: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRP-SIHREAVPPPPPQNNKPPVPSTPRP 300
S++P P P R L++ P P G P S VPPP P+ + PP P++PR
Sbjct: 1479 SAAP--EEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRA 1536
Query: 301 SASSQAPP---PPPPPS-----------RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346
S + P PPP PS P PPPL S+S E P P
Sbjct: 1537 SEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSF--EKPESPL---------- 1584
Query: 347 PLPSPGRSGPLPPPPSERPP-PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS 405
+PG PLP P+ P PPV PP PP + + TS S
Sbjct: 1585 ---TPGPPHPLPDTPAPATPLPPV--PPPAVAAAPPTLDSTASSLTSYDSEVATLTQGAS 1639
Query: 406 GVDSPRSGPRPPLPPDRPSAGAP---PPPPPST 435
P PP P P+ AP P PPP T
Sbjct: 1640 AAPGDPHPPGPPAPA-APAPAAPQPGPDPPPGT 1671
Score = 91.7 bits (226), Expect = 1e-18
Identities = 115/424 (27%), Positives = 144/424 (33%), Gaps = 117/424 (27%)
Query: 85 GGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPP 144
G GG S G P G + P R+ + + RP LPPG
Sbjct: 840 GPGGLASLGKHRPKGFFATESSFDPHHRAQPSYE------RPSFLPPG------------ 881
Query: 145 SGPGRFPVPSPGHRSGPPEPQRNRMPPPRP------DVGSKPDSIPPPVPSTPRPIQSSP 198
PG + G E R + PP V D PPP S P P S+P
Sbjct: 882 --PG---LMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTP 936
Query: 199 HNRGSPPVPGGPRQPSPGPTPPPF-PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPS 257
PVP + +P P PF PG+ G PL +SSP S P PP
Sbjct: 937 ------PVPSSSGRLTPSPRGGPFNPGSGG-----------PLPASSPASFDGPSPPDTR 979
Query: 258 RALDDKP----PPPPPPVGNRPSIHREAVPPPPPQNNK--PPVPSTPRPSASSQAPPP-- 309
+K P PP + P H PPP P ++ PP P S PPP
Sbjct: 980 VGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRL 1039
Query: 310 ---PPPPSR------PGPPPLPPSSS---------GNDETP-----RLPQRNLSLSSSTP 346
P P R P P P PS S G+ + P +LP R S + P
Sbjct: 1040 ALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVP 1099
Query: 347 PLPSPGRSGPL----------------PPPPSERPPPPVRDPPGRSGP-----LPPPPPV 385
GR GPL PP PS P + PP + P +P P +
Sbjct: 1100 ARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTII 1159
Query: 386 -----------SRNGSTSRALPATPQLPSRSG-------VDSPRSGPRPPLPPDRPSAGA 427
S GS++ A P T P+ G +P P PP P P+ +
Sbjct: 1160 IKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPAS 1219
Query: 428 PPPP 431
P P
Sbjct: 1220 PSGP 1223
Score = 79.7 bits (195), Expect = 6e-15
Identities = 131/494 (26%), Positives = 154/494 (31%), Gaps = 124/494 (25%)
Query: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
P P P P PPP T+ ++ + L IS L
Sbjct: 1658 PAAPQPGPDPPP-----GTDSGIEEVDSRSSSDHPLETISSASTLSSL------------ 1700
Query: 62 PKGAGAGGGGGGFGGGGGFGGGGGGG-----------GGGSFGGGGPPGLGGLFQAGMP- 109
+ GGG GGGGG G G G G +FGG PG Q P
Sbjct: 1701 -----SAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPS 1755
Query: 110 KLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRM 169
KLR A SGG RP P GG P SP V G + R
Sbjct: 1756 KLRGRAL--GASGGLRPG--PSGGLRDPVTPTSP-------TVSVTGAGTDGLLALRACS 1804
Query: 170 PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSP--PVPGGPRQPSPGPTPPP------ 221
PP V P ++ P VP P P SS + P PG P P PGP P
Sbjct: 1805 GPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALA 1864
Query: 222 --------------------------FPGNRGTALGGG---------------SIRQSPL 240
P RG + GGG S+++ L
Sbjct: 1865 TVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRL 1924
Query: 241 SSSSPFSNRPPLPPTPSRALDD---KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST 297
S S S L P +L KPP PP P G S A P + ST
Sbjct: 1925 SDDSQSS----LLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTST 1980
Query: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL 357
PP P P LP S PR SS P LP SGPL
Sbjct: 1981 RHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPR--------PSSLPILP----SGPL 2028
Query: 358 PPPPSERPPPPVRDPPGRSGPLPP---PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414
P + P G + P P PP +G AL + S + + S
Sbjct: 2029 YPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLS----- 2083
Query: 415 RPPLPPDRPSAGAP 428
LPPD+P P
Sbjct: 2084 ---LPPDKPFGAKP 2094
Score = 76.6 bits (187), Expect = 5e-14
Identities = 116/449 (25%), Positives = 146/449 (32%), Gaps = 53/449 (11%)
Query: 4 PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPK 63
P P PP PP A P G ++ + ++ + SA L
Sbjct: 1642 PGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLS 1701
Query: 64 GAGAGGGGGGFGGGGGFGGGG-------GGGGGGSFGGGGPPGLGGLFQAGMP-KLRSTA 115
G G GGG G G G G G +FGG PG Q P KLR A
Sbjct: 1702 AEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRA 1761
Query: 116 NRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPD 175
SGG RP P GG P SP V G + R PP
Sbjct: 1762 L--GASGGLRPG--PSGGLRDPVTPTSPT-------VSVTGAGTDGLLALRACSGPPTAG 1810
Query: 176 VGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGN---------- 225
V P ++ P VP P P SS + P G PGP PPP PG
Sbjct: 1811 VAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEG------PGPPPPPLPGPLAQPQASALA 1864
Query: 226 --RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS-IHREAV 282
+ + + S + SS P S D V R S + R+ +
Sbjct: 1865 TVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRL 1924
Query: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342
+++ + S P S P PP PP G P +++ T P + S
Sbjct: 1925 S----DDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATS--PSAS---S 1975
Query: 343 SSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402
SST G + PP R P P P P P P S+ LP+ P P
Sbjct: 1976 SSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRP-----SSLPILPSGPLYP 2030
Query: 403 SRSGV-DSPRSGPRPPLPPDRPSAGAPPP 430
+ SP G P P P P
Sbjct: 2031 GLFDIRGSPTGGAGGSADPFAPVFVPPHP 2059
Score = 62.4 bits (150), Expect = 9e-10
Identities = 83/320 (25%), Positives = 107/320 (33%), Gaps = 84/320 (26%)
Query: 157 HRSGPPEPQRNRMPPPRPDVGSKP----------DSIPPPVPSTP--RPIQSSPHNRGSP 204
H+ P Q R+PPP + SK + P PVPS R + N+
Sbjct: 767 HKKAPQ--QAKRLPPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDE 824
Query: 205 PVPGGPRQPSPGPTPPP-----FPGNRGTALGGGSIRQSPLSSSSPFSNRPP-LPPTPSR 258
+ + S +P P +R P + P RP LPP P
Sbjct: 825 ILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGL 884
Query: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP 318
L K +G PP + VP S+ PPPP S P P
Sbjct: 885 MLRQKS------IGAAEDDRPYLAPPAMKFSRSLSVPG-------SEDIPPPPTTSPPEP 931
Query: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGP 378
P STPP+PS SG L P P P PG GP
Sbjct: 932 P-----------------------YSTPPVPSS--SGRLTPSPRGGP-----FNPGSGGP 961
Query: 379 LP---------PPPPVSRNGSTSRAL-------PATPQLPSRSGVDSPRSGPR-----PP 417
LP P PP +R GS ++L PA P +P P PP
Sbjct: 962 LPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPP 1021
Query: 418 LPPDRPSAGAPPPPPPSTSI 437
PP+ + G+P PPP ++
Sbjct: 1022 HPPEMETGGSPDDPPPRLAL 1041
Score = 55.8 bits (133), Expect = 9e-08
Identities = 69/285 (24%), Positives = 86/285 (30%), Gaps = 86/285 (30%)
Query: 95 GGP--PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
GGP PG GG A P A+ D G PP G R S P P
Sbjct: 951 GGPFNPGSGGPLPASSP-----ASFD----GPSPPDTRVGSREKSLYHSGPLPPAHHHPP 1001
Query: 153 PSPGHRSGPPEPQRNRMPPPRP---DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG 209
H + PP+P + PP P + G PD PP + P+P G P PG
Sbjct: 1002 HHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGA 1061
Query: 210 PRQPSPGPTPPPFPGNRGTALG------------------GGSIRQSPLSSSSPFSNRPP 251
P G ++G AL G R+ PL + P
Sbjct: 1062 PSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQ 1121
Query: 252 ----LPPTPSRALDDKPPPPP--------------------------------------P 269
LPP PS P PPP P
Sbjct: 1122 KGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEP 1181
Query: 270 PV-----------GNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303
P G+ PS A+ P PP + P P++P A+
Sbjct: 1182 PTQPEPTGGGGGGGSSPS-PAPAMSPVPPSPSPVPTPASPSGPAT 1225
Score = 53.5 bits (127), Expect = 4e-07
Identities = 89/354 (25%), Positives = 112/354 (31%), Gaps = 77/354 (21%)
Query: 94 GGGPPGLGGLFQAGMPKLRS-----TANRDNDSGGSRPPLLPPGGRSTSAK--------P 140
G GPP G RS T+ R ++ G +LPP S + P
Sbjct: 1507 GRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEP 1566
Query: 141 FSPP-SGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI---PPPVPSTPRPIQS 196
PP F P GPP P + P P P ++ PP + ST + S
Sbjct: 1567 LPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTS 1626
Query: 197 -----------------SPHNRGSP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
PH G P P P P PGP PPP + + S
Sbjct: 1627 YDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDH 1686
Query: 239 PL---SSSSPFSNR---------------------PPLPPTPSRALDDK-------PPPP 267
PL SS+S S+ P L T LD + P PP
Sbjct: 1687 PLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPP 1746
Query: 268 PPPVGNRPSIHREAV--------PPPPPQNNKPPVPSTPRPSASSQAPPPPPP-PSRPGP 318
PP PS R P P P P++P S + + GP
Sbjct: 1747 YPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGP 1806
Query: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372
P + P +P L +SS P P GP PPPP P P+ P
Sbjct: 1807 PTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPP--LPGPLAQP 1858
Score = 50.8 bits (120), Expect = 3e-06
Identities = 66/214 (30%), Positives = 80/214 (37%), Gaps = 43/214 (20%)
Query: 63 KGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANR--DND 120
+G GG G G GGGGGS G P L FQ P+ S A
Sbjct: 1048 RGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQG---PALR-YFQLP-PRAASAAMYVPARS 1102
Query: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
G + PL+ + T + P G G P PSP + P PQ PPP S+
Sbjct: 1103 GRGRKGPLV----KQTKVEG-EPQKGGGLPPAPSP---TSPASPQ----PPPAVAAPSEK 1150
Query: 181 DSIPPP--VPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
+SIP P + P S ++GS P QP P G GGGS
Sbjct: 1151 NSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEP----------TGGGGGGGS---- 1196
Query: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
S SP P+PP+PS P P P G
Sbjct: 1197 ---SPSPAPAMSPVPPSPSPV-----PTPASPSG 1222
Score = 43.5 bits (101), Expect = 4e-04
Identities = 73/275 (26%), Positives = 92/275 (33%), Gaps = 43/275 (15%)
Query: 1 MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD 60
+P P PPPPP + + T +A +++S++S L
Sbjct: 1838 LPWEEGPGPPPPPLPGPLAQPQASALATVKA---SIISELSSK---------------LQ 1879
Query: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGL--GGLFQAGMPKLRSTANRD 118
+ G+ A GG + GG GGG GG S+ L L L S
Sbjct: 1880 QFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSS 1939
Query: 119 NDSGGSRPPLLP-PGGRSTSAKPFSPP---SGPGRFPVPSPGHRSGPP----EPQRNRMP 170
+PPL P P G S + P S S H G P R P
Sbjct: 1940 LFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAP 1999
Query: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSP------HNRGSPP-VPGGPRQPSPGPTPPPFP 223
P S+ P P PS+ + S P RGSP GG P PP P
Sbjct: 2000 SPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHP 2059
Query: 224 ---GNRGTALGGGSIRQSP-----LSSSSPFSNRP 250
G G AL G S SP L PF +P
Sbjct: 2060 GISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKP 2094
Score = 30.8 bits (68), Expect = 3.0
Identities = 21/84 (25%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 11 PPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGAGGG 70
P PT +P+ T+ + + +G + + +P+G + G
Sbjct: 462 PGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSG 521
Query: 71 GGGFGGGGGFGGGGGGGGG-GSFG 93
G GG GG GG GG GS G
Sbjct: 522 TPREGPAGGTGGSGGPGGSLGSRG 545
Score = 30.4 bits (67), Expect = 3.9
Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 17/76 (22%)
Query: 370 RDPPGRSGPLPPPPPVSRNGSTSRALP-----ATPQLPSRSGVDSPRSGPRPPLPPDRPS 424
R PPG +G PP + N TS ALP + P S SG P SG S
Sbjct: 421 RGPPG-TGLTVPPALLRANSDTSMALPDWMVFSAPGAAS-SGAPGPTSG----------S 468
Query: 425 AGAPPPPPPSTSIRNG 440
G P P+T + +G
Sbjct: 469 QGQSQPSAPTTKLSSG 484
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 111 bits (278), Expect = 1e-24
Identities = 114/378 (30%), Positives = 142/378 (37%), Gaps = 85/378 (22%)
Query: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPV--PSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI 183
PPL PP + P PPS P+ P P S PP P PPP P + +S
Sbjct: 404 PPLTPPA--PSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPS----PPPPPAQEEQEESP 457
Query: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPR------QPSPGPTPPPFPGNRGTALGG----- 232
PP VP+T RG PP+ R + P T PP P TA GG
Sbjct: 458 PPVVPAT------CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP-TPSTATGGPPEDS 510
Query: 233 -----------GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP---------PPVG 272
+IRQ + S S+R + TP R +D+ PP PP PP+
Sbjct: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSR--VIKTPRRFMDEDPPKPPKVEVSPVLRPPIT 568
Query: 273 NRPSIHREAVPPPPPQNNKPPVPSTPRP-----------------SASSQAPPP---PPP 312
P + +E P P P P PSTP P S + + PPP PPP
Sbjct: 569 TSPPVPQEPAPVPSPP-RAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPP 627
Query: 313 PSRPGPPPLPPSSSGNDETPRLPQ-----RNLSLSSST---PPLPSPGRSGPLPPPPSER 364
P P PPP P +SS R PQ +L + S PPL +P P PPP +
Sbjct: 628 PPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDS 687
Query: 365 PPPPVRDPPGRSGPLPPP---PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPD 421
P P GR+ L P P V+ + P L + + P L
Sbjct: 688 PAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQ 747
Query: 422 RPSAGAPPP-----PPPS 434
PPP PPPS
Sbjct: 748 LLPQALPPPQPQLQPPPS 765
Score = 85.5 bits (210), Expect = 1e-16
Identities = 130/519 (25%), Positives = 169/519 (32%), Gaps = 134/519 (25%)
Query: 4 PPPPAPPPPPTFALANTEKPTLNKTEQ-AGRNALLSDISKGKKLKKTVTNDRSAPILDKP 62
PP PAP PPP L P E +G +A +D+ L T P ++
Sbjct: 1960 PPGPAPSPPPPEDLG----PDFEDMEVVSGLSA--ADLDFAASLLGT------EPFQEEI 2007
Query: 63 KGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGP--------------PGLGGLFQAGM 108
AGA G GG G S P PGL G
Sbjct: 2008 VAAGA------------MGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA 2055
Query: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNR 168
P++ D+ + + P G+ T PPSGPG R+G
Sbjct: 2056 PRIEQLDGVDDGTDSEAEAVQQPRGQGT------PPSGPGVV-------RAGV------- 2095
Query: 169 MPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG-GPRQPSPGPTPPPFPGNRG 227
+G+ D PP + N G P G GPR+ S P PP G++
Sbjct: 2096 -------LGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQP 2148
Query: 228 TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR-------- 279
+ + SP + F+ P P +L P PP P +++
Sbjct: 2149 SQ----GLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKM 2204
Query: 280 --EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP---------PSRPGPPPLPPSSSGN 328
E P PPP +PP+P T P+A + PP P RP PPP PP
Sbjct: 2205 AGEGEPVPPPVK-QPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPP----- 2258
Query: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP---PPV 385
PL SGP PP V GRS P PPP P +
Sbjct: 2259 ------------------PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRL 2300
Query: 386 SRNGSTSRALPATPQL------------PSRSGV---DSP--RSGPRPPLPPDRPSAGAP 428
+G S P P L P+ GV D P +G P P S P
Sbjct: 2301 DEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
Query: 429 PPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
P + +G D E +W S+ PP P
Sbjct: 2361 LPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSP 2399
Score = 83.2 bits (204), Expect = 5e-16
Identities = 76/272 (27%), Positives = 94/272 (34%), Gaps = 60/272 (22%)
Query: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPP 311
LPP P PPPP PP P PPPPP + PP+PS P P A + PP
Sbjct: 401 LPPPPLTPPAPSPPPPLPPPSTSPP--PPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP 458
Query: 312 P------PSRPGPPPLPPSSSGNDETPRL-------PQRNLSLSSSTPPLPSP------- 351
P + G PPL PS E R P S ++ PP SP
Sbjct: 459 PVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKST 518
Query: 352 ---------------GRSGPL------------PPPPSERPPPPVRDP-------PGRSG 377
RS + P PP P +R P P
Sbjct: 519 TFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA 578
Query: 378 PLPPPPPVSRNGSTSRALP----ATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433
P+P PP ST LP + + P+ R P PP P P A +PPP P
Sbjct: 579 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA 638
Query: 434 STSIRNGFQDSPCEDEWESRFYFHPISDLPPP 465
++S R +P E+ + PPP
Sbjct: 639 TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP 670
Score = 78.2 bits (191), Expect = 2e-14
Identities = 85/315 (26%), Positives = 116/315 (36%), Gaps = 53/315 (16%)
Query: 107 GMPKLRSTANRDNDSG-----GSRPPLLPPGGRSTSAKPFSPPSGPG---------RFPV 152
G P L + + ++ G+ PP P + SP P +F +
Sbjct: 470 GRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM 529
Query: 153 PSPGHRSG----PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG 208
P RS P + PP P V P + PP+ ++P P+ P PVP
Sbjct: 530 PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSP-VLRPPITTSP-PVPQEP-----APVPS 582
Query: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS-SPFSNRPPLPPTPSRALDDKPPPP 267
PR P+P TP P P R + L + R + L+ P PP PP PS PPP
Sbjct: 583 PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPS------PPPA 636
Query: 268 PPPVGNRPSIHREAVPPPPPQNNK-PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSS 326
P RP + R P + K TP P + +AP P PPP+ P P +
Sbjct: 637 PATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAV 696
Query: 327 GNDETPRLPQ----RNLSLSSSTPPLPSPGRS-GP------LPP---------PPSERPP 366
G LP+ + + P +P S GP L P P + PP
Sbjct: 697 GRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPP 756
Query: 367 PPVRDPPGRSGPLPP 381
P PP +PP
Sbjct: 757 QPQLQPPPSPQQMPP 771
Score = 75.9 bits (185), Expect = 8e-14
Identities = 90/351 (25%), Positives = 112/351 (31%), Gaps = 77/351 (21%)
Query: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPS 189
P RS + +P +P GR PG +GP ++ + V PPPV
Sbjct: 203 PQAPRSRACEPSTPRRSRGR----PPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
Query: 190 TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG------------SIRQ 237
S G P PG PR+ G + G RG GGG ++
Sbjct: 259 VKHQTGSWKCKEGPGPGPGTPRRG--GQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKM 316
Query: 238 SPLS-----SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI--------HREAVPP 284
LS + P R + P + E
Sbjct: 317 GQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDK 376
Query: 285 PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344
+ + V P+A + PPPP P P P PP
Sbjct: 377 EGEEKEERAVAEEMMPAAEKEEAKLPPPPLTP-PAPSPP--------------------- 414
Query: 345 TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSR 404
PPLP P S P PP PPPPV PP P PPPPP S P P S
Sbjct: 415 -PPLPPPSTSPP--PPLCPPPPPPVSPPP---LPSPPPPPAQEEQEESPP-PVVPATCS- 466
Query: 405 SGVDSPRSGPRPPLPPDR----------PSAGAPPPPPPSTSIRNGFQDSP 445
R RPPL P + P +PP P PST+ +DSP
Sbjct: 467 ------RKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSP 511
Score = 73.2 bits (178), Expect = 5e-13
Identities = 125/483 (25%), Positives = 151/483 (31%), Gaps = 158/483 (32%)
Query: 93 GGGGPPGLGGLFQAGMPKLRSTA-NRD---NDSGGSRPPLLPPG--GRSTSAKPFSP--- 143
GG PP + G P+ S N D GS PP P G +SP
Sbjct: 1816 GGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRR 1875
Query: 144 PSGPGRF-PVPSPGHRSG-------------PPEPQRNRMPPPRPDVGSKPDSIPPPVPS 189
P G F P+PSPG S P P+R+R P P PPP
Sbjct: 1876 PLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPR-------PPPSRW 1928
Query: 190 TPRPIQSSPHNRGSPPVP---------GGPRQPSPGPTPPP------------------- 221
P+++SP R PP G P P P+PPP
Sbjct: 1929 ASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSA 1988
Query: 222 --------------------FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD 261
G G++ GG S SSP S P T A
Sbjct: 1989 ADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPG--DSSEEESSPTSRYIHFPVTVVSAPG 2046
Query: 262 DKPPPPPPP--------VGNRPSIHREAVPPPPPQNNKPPVPSTPRP----SASSQAPPP 309
P P V + EAV P Q P P R +A +A PP
Sbjct: 2047 LAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPP 2106
Query: 310 PPPPSR----------------PGP-----PPLPPSSSGNDETPRLPQRNLSLSSSTPP- 347
PS GP PP PP ++G+ P + L+ S + P
Sbjct: 2107 EDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQ-----PSQGLTASPADPTR 2161
Query: 348 ----LP-SPG----RSGPLPPPPS-----------------------ERPPPPVRDPPGR 375
LP +PG GP P PP E PPPV+ PP
Sbjct: 2162 TFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPP-- 2219
Query: 376 SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST 435
PP +S TS LP P L V R P PP PP + P PP
Sbjct: 2220 -----LPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQ 2274
Query: 436 SIR 438
+IR
Sbjct: 2275 AIR 2277
Score = 70.9 bits (172), Expect = 3e-12
Identities = 72/240 (30%), Positives = 84/240 (35%), Gaps = 55/240 (22%)
Query: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323
PPP PP + P PP PP + PP P P P PPP PP P PPP P
Sbjct: 403 PPPLTPPAPSPP-------PPLPPPSTSPPPPLCPPP------PPPVSPPPLPSPPPPPA 449
Query: 324 SSSGNDETPRLPQRNLSLSSSTPPL-PS------PGRSGPL-PPPPSERPPPPVRDPPGR 375
+ P + S PPL PS R+GP PP+ P PP
Sbjct: 450 QEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPED 509
Query: 376 SGPLPPP-------------PPVSRNGS----TSRAL----PATPQLPSRSGVDSPRSGP 414
S + P P VS S T R P P S V P
Sbjct: 510 SPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
Query: 415 RPPLPPDRPSAGAPP--PPPPSTSI-----RNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
PP+P + +PP P PPST + R P W S +LPPP P
Sbjct: 570 SPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP-TFRWTSL-----TRELPPPPP 623
Score = 68.2 bits (165), Expect = 2e-11
Identities = 102/381 (26%), Positives = 129/381 (33%), Gaps = 61/381 (16%)
Query: 137 SAKPFSPPSGPGRFPVPSPGHRSGPPE---PQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
S P S P G P+ + G PE P +N PP RPD G S PPP P
Sbjct: 1807 SPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSG----SAPPPAP----- 1857
Query: 194 IQSSPHNRGSPPVPGGPRQPSPGPT--PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251
+S R P R+P G + P P PG+ S L+ P P
Sbjct: 1858 -RSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGS-----------PSSLTHHIPTVGDPD 1905
Query: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP--PPPQNNKPPVPS--TPRPSASSQAP 307
P P R+ P P PP PS R A PP PQ PP S T S +
Sbjct: 1906 FPAPPRRSRRPSPLAPRPP----PS--RWASPPLKTSPQLRVPPPTSVVTALTPTSGELA 1959
Query: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS---TPP----LPSPGRSGPLPPP 360
PP P PS P P L P + L +L ++S T P + + G G
Sbjct: 1960 PPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGG 2019
Query: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420
P + P R P VS G A P P++ GVD +
Sbjct: 2020 PGDSSEEE-SSPTSRYIHF-PVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV-- 2075
Query: 421 DRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA 480
+P PP P +R G + + PPE + K
Sbjct: 2076 QQPRGQGTPPSGPGV-VRAGVLGAAGD-------------RARPPEDLPSEIVDFVLKNL 2121
Query: 481 RNESRSGSNRRERGAPPLPPI 501
G+ RE PP PP+
Sbjct: 2122 GGPGDGGAGPREESLPPAPPL 2142
Score = 67.0 bits (162), Expect = 4e-11
Identities = 56/161 (34%), Positives = 66/161 (40%), Gaps = 48/161 (29%)
Query: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339
EA PPPP PP PS P PP PPP + P PP PP P P
Sbjct: 398 EAKLPPPPLT--PPAPSPP--------PPLPPPSTSPPPPLCPP--------PPPP---- 435
Query: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP 399
S PPLPSP PPPP ++ S PPP V S R P P
Sbjct: 436 ---VSPPPLPSP-------------PPPPAQEEQEES----PPPVVPATCSRKRGRP--P 473
Query: 400 QLPS-RSGVDSPRSGPR---PPLPPDRPSAGAPPPPPPSTS 436
PS R+ ++ R+GP PP P + G PP P+ +
Sbjct: 474 LTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVA 514
Score = 58.9 bits (141), Expect = 1e-08
Identities = 126/513 (24%), Positives = 172/513 (33%), Gaps = 126/513 (24%)
Query: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFG-GGGPPG-------LGGLFQAGMPKLR 112
+P+GAG GGG GG G G GGG+ G GG PG L GL + G+ +LR
Sbjct: 23 RPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAEPGEDTALLRLLGL-RRGLRRLR 81
Query: 113 STANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPP 172
+ P + GR GP R VP G + + +
Sbjct: 82 RL--------WAGPRVQRGRGRGRGR-----GWGPSRGCVPEEESSDGESDEEEFQ---- 124
Query: 173 RPDVGSKPDSIPPPVPSTPRPIQS-SPHNRG----SPPVPGGPRQPSPGPTPPPFP---- 223
S D P + S R + +P RG + P+P PR PTPP P
Sbjct: 125 --GFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLP-PPRLADVAPTPPKTPARKR 181
Query: 224 GNRGTALGGGSIRQSPLSSSSPFS--NRPPLPPTPSRALDDKPPPPPPPVGNRPS---IH 278
G GT ++ + + +P + +R P TP R+ P P P + +
Sbjct: 182 GEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVA 241
Query: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRP-------------------GPP 319
AV P P+ P VP + + P P P P G
Sbjct: 242 EAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGL 301
Query: 320 PLPPSSSGNDETPRLPQRNLSLSS---------STPPLP----SPGRSG---------PL 357
P + ++ Q +L L S S +P G+ G L
Sbjct: 302 PFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKL 361
Query: 358 PPPPSERPPPPVRDPPG-----RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
E+ +D G R+ P + + P TP PS
Sbjct: 362 DDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS--------- 412
Query: 413 GPRPPLPPDRPSAGAPPP--PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQ 470
P PPLPP PS PPP PPP + SP P+ PPP +
Sbjct: 413 -PPPPLPP--PSTSPPPPLCPPPPPPV------SP-----------PPLPSPPPPPAQEE 452
Query: 471 TTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
+S P + S R+RG PPL P R
Sbjct: 453 QEESPPPVVPATCS------RKRGRPPLTPSQR 479
Score = 32.7 bits (73), Expect = 0.79
Identities = 41/153 (26%), Positives = 51/153 (33%), Gaps = 7/153 (4%)
Query: 303 SSQAPPPPPPPSRP----GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
S +A P PP P R GP + G +E L QR S PS
Sbjct: 1035 SPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRK-SARRCVKQRPSYDIFEDSD 1093
Query: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418
PP P R P R LP P P ++ L QL +R +D P P
Sbjct: 1094 DSEPGGPPAPRRRTP-RENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFA 1152
Query: 419 PPDRPSAGAPPPPPPSTSIRNGF-QDSPCEDEW 450
G P +R F +D E+ W
Sbjct: 1153 SFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVW 1185
Score = 30.4 bits (67), Expect = 3.9
Identities = 10/10 (100%), Positives = 10/10 (100%)
Query: 4 PPPPAPPPPP 13
PPPPAPPPPP
Sbjct: 620 PPPPAPPPPP 629
Score = 29.6 bits (65), Expect = 6.7
Identities = 11/29 (37%), Positives = 15/29 (51%)
Query: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQ 30
P PPPP P PP ++ +P L + Q
Sbjct: 623 PAPPPPPAPSPPPAPATSSRRPLLLRAPQ 651
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 111 bits (277), Expect = 2e-24
Identities = 99/325 (30%), Positives = 123/325 (37%), Gaps = 61/325 (18%)
Query: 60 DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDN 119
D+ + G GGGG GGGGG GG PPG+ G+ + R
Sbjct: 4 DRFRSRGGGGGGFH------RRGGGGGRGGLHDFRSPPPGM------GLNQNRGPMGPGP 51
Query: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP-PEPQRNRMPPPRPDVGS 178
G +PP+ PP +P PP P P P H+ P P+P + + PPP P S
Sbjct: 52 GQSGPKPPIPPPPPHQQQQQP--PPQQPP--PQQPPPHQPPPHPQPHQQQQPPPPPQDSS 107
Query: 179 KPDSIPPPVPST---PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSI 235
KP P P+ P SS +PP G P PGPTP P
Sbjct: 108 KPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP-------------- 153
Query: 236 RQSPLSSSSPFSNRPPLPPTPSRALDDKPP----PPPPPVGNRPSIHREAVPPPPPQNNK 291
P +S+P PP P PS + PP PPPPP AVP P P +
Sbjct: 154 --PPAVTSAPPGAPPPTP--PSSGVPTTPPQAGGPPPPPA---------AVPGPGPGPKQ 200
Query: 292 PPVPSTPRPSASSQAPPPPPPP--SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLP 349
P P P+ P P P S PG P PP G + PR +++ PP
Sbjct: 201 GPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE--PRGGRQH------HPPYH 252
Query: 350 SPGRSGPLPPPPSERPPPPVRDPPG 374
GP P P R + D G
Sbjct: 253 QQHHQGPPPGGPGGRSEEKISDSEG 277
Score = 97.8 bits (242), Expect = 2e-20
Identities = 86/262 (32%), Positives = 109/262 (41%), Gaps = 63/262 (24%)
Query: 190 TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNR 249
+P P NRG P+ GP Q P P PP P ++ +Q P
Sbjct: 33 SPPPGMGLNQNRG--PMGPGPGQSGPKPPIPPPPPHQQ--------QQQP---------- 72
Query: 250 PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN-KPPVPSTPRPS------- 301
PP P P + +PPP P P H++ PPPPPQ++ KP V P P+
Sbjct: 73 PPQQPPPQQPPPHQPPPHPQP-------HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAP 125
Query: 302 -ASSQAPP--PP----PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP--PLPSPG 352
ASS APP PP PP S PGP P PP +++S+ P P P+P
Sbjct: 126 PASSSAPPATPPTSGAPPGSGPGPTPTPPP---------------AVTSAPPGAPPPTPP 170
Query: 353 RSG-PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPR 411
SG P PP + PPPP PG GP P P G +P P+ G+ +P
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVPG-PGPGPKQGP-GPGGPKGGKMPGGPKPGGGPGLSTPG 228
Query: 412 SGPRPP-LPPDRPSAGAPPPPP 432
P+PP P G PP
Sbjct: 229 GHPKPPHRGGGEPRGGRQHHPP 250
Score = 97.4 bits (241), Expect = 3e-20
Identities = 110/334 (32%), Positives = 124/334 (37%), Gaps = 92/334 (27%)
Query: 83 GGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPG-GRSTSAKPF 141
GGGGGG GGGG G GGL P PPG G + + P
Sbjct: 10 GGGGGGFHRRGGGG--GRGGLHDFRSP--------------------PPGMGLNQNRGPM 47
Query: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNR 201
P GPG+ SGP P +PPP P + P P P P Q PH
Sbjct: 48 GP--GPGQ---------SGPKPP----IPPPPPHQQQQQ-----PPPQQPPPQQPPPHQ- 86
Query: 202 GSPPVPGGPRQPSPGPTPPPFPGNR---------GTALGGGSIRQSPLSSSSPFSNRPPL 252
PP P QP PPP P + G A G GS P SSS+P P
Sbjct: 87 -PPPHP----QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGS--APPASSSAP----PAT 135
Query: 253 PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP 312
PPT P P P P S A PP PP + VP+TP P A PPPPP
Sbjct: 136 PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSG---VPTTP-PQAGG---PPPPP 188
Query: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR-- 370
+ PGP P P G P P+ P P PG GP P P PP R
Sbjct: 189 AAVPGPGPGPKQGPG----PGGPK-----GGKMPGGPKPG-GGPGLSTPGGHPKPPHRGG 238
Query: 371 -DPPGRSGPLPP--------PPPVSRNGSTSRAL 395
+P G PP PPP G + +
Sbjct: 239 GEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKI 272
Score = 85.1 bits (209), Expect = 1e-16
Identities = 59/169 (34%), Positives = 69/169 (40%), Gaps = 20/169 (11%)
Query: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP-PPPPPSRPGPPPLPPSSSGNDE 330
G R +H PPP N+ P P P S PP PPPPP + P P
Sbjct: 23 GGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP 82
Query: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
P P PP P P + PPPP + P V PG + + PP S
Sbjct: 83 PPHQP----------PPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPAS---- 128
Query: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA--GAPPPPPPSTSI 437
S A PATP P+ GP P PP SA GAPPP PPS+ +
Sbjct: 129 -SSAPPATP--PTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174
Score = 32.7 bits (73), Expect = 0.79
Identities = 26/93 (27%), Positives = 34/93 (36%), Gaps = 10/93 (10%)
Query: 69 GGGGGFGGGGGFGGGGGG----GGGGSFGGGGPPGL------GGLFQAGMPKLRSTANRD 118
GGGG G +G GG GGGG G PG+ G + + M R
Sbjct: 613 GGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFGQGGA 672
Query: 119 NDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP 151
GG P + PG + + GP + P
Sbjct: 673 GPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKP 705
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 111 bits (277), Expect = 2e-24
Identities = 121/421 (28%), Positives = 146/421 (34%), Gaps = 83/421 (19%)
Query: 103 LFQAGMPKLRSTANRDNDSGGSRP--PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160
+ QA P L++ + P P LP G + SA P P P+
Sbjct: 179 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 238
Query: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207
P P + P P PPP PS P+Q + G P P
Sbjct: 239 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298
Query: 208 ------GGPRQPSPGPTPP---PFPGNRGTALGGGS--------IRQSPLSSSSPFSNRP 250
GP PGP P P ++G A G S Q P S S+ S +P
Sbjct: 299 GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP 358
Query: 251 ----PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
PLPP P KPPP P P + P P + PP S P P + +
Sbjct: 359 PREQPLPPAPLAMPHIKPPPTTP----IPQL------PAPQAHKHPPHLSGPSPFSMNAN 408
Query: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS-----PG--RSGPLPP 359
PPPP P SS P L L + PLPS PG +S LPP
Sbjct: 409 LPPPPALK-------PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 461
Query: 360 PPSERP----------PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV-- 407
PP+ P PP + P GP P PP + ST A P T P SG
Sbjct: 462 PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAA 521
Query: 408 --DSPRSGPRPPLP---------PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYF 456
S G PLP D +PPPPP S S D+P +RFY
Sbjct: 522 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 581
Query: 457 H 457
H
Sbjct: 582 H 582
Score = 78.2 bits (191), Expect = 2e-14
Identities = 94/325 (28%), Positives = 114/325 (35%), Gaps = 58/325 (17%)
Query: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277
T P P + S Q + + P + + P TP+ + P P G PS
Sbjct: 157 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS- 215
Query: 278 HREAVPPP----------PPQNNKPPVPST---PRPSASSQAPPPPPPPSRPGP-PPLPP 323
AVPP PQ PVP T P+ Q PP P PP P P PPL P
Sbjct: 216 -ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 274
Query: 324 --SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
S+G P Q L PP P ++GPL P PP P PP S P
Sbjct: 275 LTGSAGQPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPG--PPQPFGLPPQASQGQAP 330
Query: 382 --PPPVSRNGSTSRALPATPQLPSRSGVDS---PRSGPRPPLPPDRPSAGAPP------- 429
P + TS LPA S+S + S PR P PP P P PP
Sbjct: 331 LGTSPAAAYPHTSLQLPA-----SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 385
Query: 430 --------PP----PPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477
PP P S+ P S HP S PPP + ++ PS
Sbjct: 386 PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 445
Query: 478 KLARNESRSGSNRRERGAPPLPPIP 502
A+ + S LPP P
Sbjct: 446 SPAQPPGLTQSQN-------LPPPP 463
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 111 bits (277), Expect = 2e-24
Identities = 121/421 (28%), Positives = 146/421 (34%), Gaps = 83/421 (19%)
Query: 103 LFQAGMPKLRSTANRDNDSGGSRP--PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160
+ QA P L++ + P P LP G + SA P P P+
Sbjct: 733 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792
Query: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207
P P + P P PPP PS P+Q + G P P
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852
Query: 208 ------GGPRQPSPGPTPP---PFPGNRGTALGGGS--------IRQSPLSSSSPFSNRP 250
GP PGP P P ++G A G S Q P S S+ S +P
Sbjct: 853 GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP 912
Query: 251 ----PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
PLPP P KPPP P P + P P + PP S P P + +
Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTP----IPQL------PAPQAHKHPPHLSGPSPFSMNAN 962
Query: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS-----PG--RSGPLPP 359
PPPP P SS P L L + PLPS PG +S LPP
Sbjct: 963 LPPPPALK-------PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015
Query: 360 PPSERP----------PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV-- 407
PP+ P PP + P GP P PP + ST A P T P SG
Sbjct: 1016 PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAA 1075
Query: 408 --DSPRSGPRPPLP---------PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYF 456
S G PLP D +PPPPP S S D+P +RFY
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135
Query: 457 H 457
H
Sbjct: 1136 H 1136
Score = 78.2 bits (191), Expect = 2e-14
Identities = 94/325 (28%), Positives = 114/325 (35%), Gaps = 58/325 (17%)
Query: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277
T P P + S Q + + P + + P TP+ + P P G PS
Sbjct: 711 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS- 769
Query: 278 HREAVPPP----------PPQNNKPPVPST---PRPSASSQAPPPPPPPSRPGP-PPLPP 323
AVPP PQ PVP T P+ Q PP P PP P P PPL P
Sbjct: 770 -ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 828
Query: 324 --SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
S+G P Q L PP P ++GPL P PP P PP S P
Sbjct: 829 LTGSAGQPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPG--PPQPFGLPPQASQGQAP 884
Query: 382 --PPPVSRNGSTSRALPATPQLPSRSGVDS---PRSGPRPPLPPDRPSAGAPP------- 429
P + TS LPA S+S + S PR P PP P P PP
Sbjct: 885 LGTSPAAAYPHTSLQLPA-----SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 939
Query: 430 --------PP----PPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477
PP P S+ P S HP S PPP + ++ PS
Sbjct: 940 PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 999
Query: 478 KLARNESRSGSNRRERGAPPLPPIP 502
A+ + S LPP P
Sbjct: 1000 SPAQPPGLTQSQN-------LPPPP 1017
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 111 bits (277), Expect = 2e-24
Identities = 121/421 (28%), Positives = 146/421 (34%), Gaps = 83/421 (19%)
Query: 103 LFQAGMPKLRSTANRDNDSGGSRP--PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160
+ QA P L++ + P P LP G + SA P P P+
Sbjct: 733 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792
Query: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207
P P + P P PPP PS P+Q + G P P
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852
Query: 208 ------GGPRQPSPGPTPP---PFPGNRGTALGGGS--------IRQSPLSSSSPFSNRP 250
GP PGP P P ++G A G S Q P S S+ S +P
Sbjct: 853 GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP 912
Query: 251 ----PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
PLPP P KPPP P P + P P + PP S P P + +
Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTP----IPQL------PAPQAHKHPPHLSGPSPFSMNAN 962
Query: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS-----PG--RSGPLPP 359
PPPP P SS P L L + PLPS PG +S LPP
Sbjct: 963 LPPPPALK-------PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015
Query: 360 PPSERP----------PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV-- 407
PP+ P PP + P GP P PP + ST A P T P SG
Sbjct: 1016 PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAA 1075
Query: 408 --DSPRSGPRPPLP---------PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYF 456
S G PLP D +PPPPP S S D+P +RFY
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135
Query: 457 H 457
H
Sbjct: 1136 H 1136
Score = 78.2 bits (191), Expect = 2e-14
Identities = 94/325 (28%), Positives = 114/325 (35%), Gaps = 58/325 (17%)
Query: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277
T P P + S Q + + P + + P TP+ + P P G PS
Sbjct: 711 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS- 769
Query: 278 HREAVPPP----------PPQNNKPPVPST---PRPSASSQAPPPPPPPSRPGP-PPLPP 323
AVPP PQ PVP T P+ Q PP P PP P P PPL P
Sbjct: 770 -ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 828
Query: 324 --SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
S+G P Q L PP P ++GPL P PP P PP S P
Sbjct: 829 LTGSAGQPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPG--PPQPFGLPPQASQGQAP 884
Query: 382 --PPPVSRNGSTSRALPATPQLPSRSGVDS---PRSGPRPPLPPDRPSAGAPP------- 429
P + TS LPA S+S + S PR P PP P P PP
Sbjct: 885 LGTSPAAAYPHTSLQLPA-----SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 939
Query: 430 --------PP----PPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477
PP P S+ P S HP S PPP + ++ PS
Sbjct: 940 PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 999
Query: 478 KLARNESRSGSNRRERGAPPLPPIP 502
A+ + S LPP P
Sbjct: 1000 SPAQPPGLTQSQN-------LPPPP 1017
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 110 bits (274), Expect = 4e-24
Identities = 96/341 (28%), Positives = 124/341 (36%), Gaps = 56/341 (16%)
Query: 130 PPGGRSTSAKPFSPPSGPGRFPV-PSPGHRSGPPEPQRNRMPP---PRPDVGSKPDSIPP 185
PP +T+ P + PS P P P PP PP P P + + P
Sbjct: 1408 PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPT 1467
Query: 186 PVPSTPRPIQSSPHNRGSPPV-----PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
PS P S P SPP P PSP T P P T L + P
Sbjct: 1468 TTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPT 1527
Query: 241 SSS---------SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291
+++ SP + P PPT + L P PPP PPP
Sbjct: 1528 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT--------TTTTPPPTTTPS 1579
Query: 292 PPVPSTPRP-SASSQAPPP-------------PPPPSRPGPPPLPPSSSGNDETPRLPQR 337
PP +TP P + ++ PPP PPP + P PP P TP P
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI------TP--PTS 1631
Query: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR---DPPGRSGPLPPPPPVSRNGSTSRA 394
+L +T P P P + PPP+ P PP PP + PPP + T+
Sbjct: 1632 TTTLPPTTTPSPPP--TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689
Query: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST 435
P T + + S +P S P PS+ P PPP+T
Sbjct: 1690 SPPTTTMTTPSPTTTPSS---PITTTTTPSSTTTPSPPPTT 1727
Score = 94.7 bits (234), Expect = 2e-19
Identities = 87/339 (25%), Positives = 122/339 (35%), Gaps = 43/339 (12%)
Query: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRS--GPPEPQR 166
P + +T + S P P +T + P + + P PSP + PP
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTT 1515
Query: 167 NRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNR 226
P P + + PPP +TP P ++P +PP P+ P+PPP
Sbjct: 1516 TLPPTTTPSPPTTTTTTPPPT-TTPSPPTTTPI---TPPTSTTTLPPTTTPSPPPTT--- 1568
Query: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPP 286
+ P ++ SP + P PPT + P PP + P PP
Sbjct: 1569 -------TTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP 1621
Query: 287 PQNN-KPPVPSTPRPSASSQAPPP-----PPPPSRPGPP----PLPPSSSGNDETPRLPQ 336
PP +T P ++ +PPP PPP + P PP P PP + T P
Sbjct: 1622 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT-----TTTTPP 1676
Query: 337 RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
+ SS PSP + P P+ P P+ S P PP P
Sbjct: 1677 PTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPP-----------P 1725
Query: 397 ATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPP-PPS 434
T PS + SP + LPP S+ P PPS
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764
Score = 89.7 bits (221), Expect = 5e-18
Identities = 85/329 (25%), Positives = 119/329 (36%), Gaps = 53/329 (16%)
Query: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG------PPEPQRNRMPPPRPDVGSKPDSI 183
PP +T+ P + PS P P+ P + P P PP S P +
Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545
Query: 184 P--PPVPSTPRPIQSSPHNRGSPP-----VPGGPRQPSPGPTPPPFPGNRGTALGGGSIR 236
P PP +T P ++P SPP P PSP T P P T +
Sbjct: 1546 PITPPTSTTTLPPTTTP----SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601
Query: 237 QSP--LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPV 294
SP ++++P P PPT + P PP PPP PP
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTT--------PITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653
Query: 295 PSTPRPSASSQAPPP------PPPPSRPGPP----PLPPSSSGNDETPRLPQRNLSLSSS 344
+TP P ++ PP PPP + P P P PP+++ +P + +++
Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT 1713
Query: 345 TP---PLPSPGRSGPLPPPPSERP----------PPPVRDPPGRSGPLPP---PPPVSRN 388
TP PSP + P P+ P PP P + PLPP PP S
Sbjct: 1714 TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPF 1773
Query: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPP 417
+T+ P P +DS + P
Sbjct: 1774 STTTPTTPCVPLCNWTGWLDSGKPNFHKP 1802
Score = 89.4 bits (220), Expect = 7e-18
Identities = 78/296 (26%), Positives = 106/296 (35%), Gaps = 41/296 (13%)
Query: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP-PPVP 188
PP +T+ P + PS P P+ P + P P PPP P + P PP
Sbjct: 1525 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP-PTTTPSPPPTTTTTPPPTTTPSPPTT 1583
Query: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
+TP P + +PP P P+ T PP P ++ SP +
Sbjct: 1584 TTPSPPTITTT---TPPPTTTPSPPTTTTTTPP-----------------PTTTPSPPTT 1623
Query: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
P PPT + L P PPP PPP PP +TP P ++ P
Sbjct: 1624 TPITPPTSTTTLPPTTTPSPPPT--------TTTTPPPTTTPSPPTTTTPSPPITTTTTP 1675
Query: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP-GRSGPLPPPPSERPPP 367
PP + P+ + S T P + SS +P + P PPP + P
Sbjct: 1676 PP---TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS 1732
Query: 368 PVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP 423
P P + + PP +TS L TP PS + P P P P
Sbjct: 1733 PTTTPSPPTTTMTTLPPT----TTSSPLTTTPLPPS---ITPPTFSPFSTTTPTTP 1781
Score = 88.6 bits (218), Expect = 1e-17
Identities = 69/256 (26%), Positives = 100/256 (39%), Gaps = 38/256 (14%)
Query: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP---- 268
PSP T P P T L + P ++++ PP TPS + PPP
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTT----PPPTTTPSPPITTTTTPPPTTTP 1454
Query: 269 -PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
PP+ + P PP PP + P+ ++ PPP PS P P+ P +S
Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 328 NDETPRLPQRNLSLSSSTPP---LPSPGRSGPLPPP-------PSERPPPP---VRDPPG 374
P + +++TPP PSP + P+ PP P+ P PP PP
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574
Query: 375 RSGPLPP------PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP-----LPPDRP 423
+ P PP PP ++ P+ P + + P + P PP PP
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPP--TTTTTTPPPTTTPSPPTTTPITPPTST 1632
Query: 424 SAGAP---PPPPPSTS 436
+ P P PPP+T+
Sbjct: 1633 TTLPPTTTPSPPPTTT 1648
Score = 68.2 bits (165), Expect = 2e-11
Identities = 60/195 (30%), Positives = 78/195 (40%), Gaps = 30/195 (15%)
Query: 262 DKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---PPPP---SR 315
DK P P PS PPP PP + P+ ++ PPP P PP +
Sbjct: 1393 DKCITTPSPPTTTPS------PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTT 1446
Query: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSSTP----PLPSPGRSGPLPPPPSERPPPPVR- 370
PP PS + T P S ++TP PSP + PPP+ P PP
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1506
Query: 371 --DPPGRSGPLPPPPPVSRNGSTSRALP--ATPQLPSRSGVDSPRSGPRPPLPPDRPSAG 426
PP + LPP S +T+ P TP P+ + + P S P P PS
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP-PTTTPS-- 1563
Query: 427 APPP-----PPPSTS 436
PPP PPP+T+
Sbjct: 1564 -PPPTTTTTPPPTTT 1577
Score = 66.2 bits (160), Expect = 6e-11
Identities = 79/335 (23%), Positives = 122/335 (36%), Gaps = 42/335 (12%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 3962 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 4020
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 4021 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 4078
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN 290
Q+P +++P + + PTP+ P P+ ++ P P P
Sbjct: 4079 ------QTP--TTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTV----TPTPTPTGT 4124
Query: 291 KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350
+ P T P ++ P P P+ P P ++ TP P + + +T P+ +
Sbjct: 4125 QTP---TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITT 4180
Query: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPLPP--PPPVSRNGSTSRAL--PATPQLPSRSG 406
P P P + PP L PPP S TSR+ P T S
Sbjct: 4181 TTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST 4240
Query: 407 VD-----SPRSGPRPPLPPDRPSAGAPPPPPPSTS 436
+ + + P P P S G PPPST+
Sbjct: 4241 LPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT 4275
Score = 59.3 bits (142), Expect = 8e-09
Identities = 69/296 (23%), Positives = 107/296 (36%), Gaps = 34/296 (11%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 4031 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 4089
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 4090 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 4147
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN 290
Q+P +++P + + PTP+ P P+ ++ P P
Sbjct: 4148 ------QTP--TTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTV--TPTPTPTGTQT 4195
Query: 291 KPPVPSTPRPSASSQAPPPPPPPSRPGPP-----PLPPSSSGNDETPRLPQRNLSLSSST 345
PP ++ P A PPP S P PL S++ P + + ST
Sbjct: 4196 GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255
Query: 346 PPLPSPGRSGPL--PPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP 399
P P+ G PPP + PP +G P P + +T+ A TP
Sbjct: 4256 PTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTP 4311
Score = 56.6 bits (135), Expect = 5e-08
Identities = 82/350 (23%), Positives = 113/350 (32%), Gaps = 88/350 (25%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 4077 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 4135
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 4136 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4195
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRA-------------LDDKPP--------PPPP 269
G + + + SN PP TP + L PP PP
Sbjct: 4196 GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255
Query: 270 PVGNRPSIHREAVPPPPPQNNKPP---------------VPSTPRPSASSQAPPPPPPPS 314
P + + PPP PP PST + + +S P P P S
Sbjct: 4256 PTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS 4315
Query: 315 RP------GPPPLPPS------------SSGNDE----------------TPRLPQRNLS 340
P G P P S + G + + L N S
Sbjct: 4316 TPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWS 4375
Query: 341 LSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP--PPPVSRN 388
S+ P P+P +S P P PS P P PG P P PP N
Sbjct: 4376 CPSTPSPTPTPSKSTPTPSKPSSTPSKPT---PGTKPPECPDFDPPRQEN 4422
Score = 51.2 bits (121), Expect = 2e-06
Identities = 74/349 (21%), Positives = 122/349 (34%), Gaps = 49/349 (14%)
Query: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQ 165
P +T +N + PP P +T+ P P+G P P+ + + P P
Sbjct: 1882 PTTMTTTTTENPT----PPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1937
Query: 166 RNRMPPPRPDVGSKPDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP---- 217
+ P P + + P P P+ TP + +P P P G + P+ P
Sbjct: 1938 GTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1996
Query: 218 -TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS 276
T P P GT Q+P +++P + + PTP+ P P
Sbjct: 1997 TTVTPTPTPTGT--------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTP-------- 2038
Query: 277 IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQ 336
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 2039 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TPT 2096
Query: 337 RNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSRA 394
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTP 2153
Query: 395 LPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 2007 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 2065
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 2066 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 2123
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 2124 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2175
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 2233
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 2290
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2340
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 2145 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 2203
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 2204 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 2261
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 2262 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2313
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 2314 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 2371
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 2372 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 2428
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 2429 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 2283 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 2341
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 2399
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 2400 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 2509
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 2510 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 2566
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 2567 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2616
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 2421 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 2479
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 2480 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 2537
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 2538 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2589
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 2590 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 2647
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 2648 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 2704
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 2705 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2754
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 2559 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 2617
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 2618 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 2675
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 2676 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2727
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 2728 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 2785
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 2786 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 2842
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 2843 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 2697 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 2755
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 2756 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 2813
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 2814 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2865
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 2866 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 2923
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 2980
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 2981 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 2835 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 2893
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 2951
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 2952 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3003
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 3061
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 3062 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 3118
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 3119 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 2973 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 3031
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 3032 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 3089
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 3090 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3141
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 3142 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 3199
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 3200 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 3256
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 3257 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 3111 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 3169
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 3227
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 3228 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 3337
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 3338 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 3394
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 3395 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 3249 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 3307
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 3308 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 3365
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 3366 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 3418 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 3475
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 3476 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 3532
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 3533 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 3387 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 3445
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 3503
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 3504 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3555
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 3556 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 3613
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 3614 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 3670
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 3671 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3720
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 3525 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 3583
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 3641
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 3642 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3693
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 3694 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 3751
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 3752 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 3808
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 3809 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 3663 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 3721
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 3779
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 3780 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3831
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 3832 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 3889
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 3890 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 3946
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 3947 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3996
Score = 50.8 bits (120), Expect = 3e-06
Identities = 74/350 (21%), Positives = 122/350 (34%), Gaps = 52/350 (14%)
Query: 123 GSRPPLLPPGGRSTSAKPFSPPSG---PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
G++ P P +T+ P P+G P P+ + + P P + P P + +
Sbjct: 3801 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 3859
Query: 180 PDSIPPPVPS---TPRPIQSSPHNRGSP-PVPGGPRQPSPGP-----TPPPFPGNRGTAL 230
P P P+ TP + +P P P G + P+ P T P P GT
Sbjct: 3860 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-- 3917
Query: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----------PPPPPVGNRPS--- 276
Q+P +++P + + PTP+ P P P P G +
Sbjct: 3918 ------QTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3969
Query: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
I P P P+T + ++ P P P P P +++ TP P
Sbjct: 3970 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTP-TP 4027
Query: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--PPVRDPPGRSGPLPPPPPVSRNGSTSR 393
+ + +T P+ + P P P + P P+ + P P P T+
Sbjct: 4028 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTT 4084
Query: 394 ALPATPQL---PSRSGVDSPRSGP----RPPLPPDRPSAGAPPPPPPSTS 436
+ T + P+ +G +P + P P P+ P P T+
Sbjct: 4085 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4134
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 109 bits (272), Expect = 7e-24
Identities = 111/382 (29%), Positives = 134/382 (35%), Gaps = 41/382 (10%)
Query: 127 PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPP 186
P PP A PFSPP+ P P +P ++ P PP P P
Sbjct: 664 PFSPPPSPPVQA-PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722
Query: 187 VPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPF 246
P P P+ + P PP P SP TPPP R PL ++ P
Sbjct: 723 PPQAPPPLAAPPLQ--VPPSPPASPPMSPSATPPP--------------RVPPLLAAPPL 766
Query: 247 SNRPPLPPTPSRALD----DKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSA 302
+PP+P +L KPPP PP P + PP P PS P +
Sbjct: 767 Q----VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
Query: 303 SSQAPPPPPPPSRPGP----PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
PPP PP P PP PP+S R P S S P L GP P
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP-P 881
Query: 359 PPPSERPPPPVRDP--PGRSGPLPPPPPVSR--NGSTSRALPATPQLPSRSGVDSPRSGP 414
PPPS P + P G S P R + A+P + P +
Sbjct: 882 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 941
Query: 415 RPPLPP--DRPSAGAPPPPPPSTSIRNGFQDSPC---EDEWESRFYFHPISDLPPPEPYV 469
R P PP R + GAP P PP+T G D C E E P + P P P
Sbjct: 942 RGPAPPLAFRGAPGAPLPWPPATG--PGSADGLCTIYETEGPESATPAPGALDPGPSPGT 999
Query: 470 QTTKSYPSKLARNESRSGSNRR 491
K+ A SRS R
Sbjct: 1000 SGGKAAAGAGAGASSRSPKQAR 1021
Score = 104 bits (259), Expect = 2e-22
Identities = 102/336 (30%), Positives = 129/336 (38%), Gaps = 49/336 (14%)
Query: 155 PGHRSGPPEPQRNRMPPPRPDVGSKPDSIP----PPVPSTPRPIQSSPHNRGSPPVPGGP 210
P + PP + PP S P + P PP P+ P P+Q+ P +PP P
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPLTTPP----P 581
Query: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270
PS TPPP Q+P + +SP P PP A PPP PP
Sbjct: 582 ETPSSIATPPP---------------QAPPALASPPLQGLPSPPLSPLAT---PPPQAPP 623
Query: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ---APPPPPPPSRPGPPPLPPSSSG 327
P + PP P + PS P+A + P PPPS P P P +S
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Query: 328 NDETPRLPQRNLSLSSSTPPL---PSPGRSGPLPP--PPSERPPPPVRDPPGRSGPLPP- 381
P S + PPL PSP S P+ P P + PPP+ PP + P PP
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 382 PPPVSRNGS-TSRALPATPQLPSRSGVDSPRSGPRPPL---PPDRPSAGAPPP----PPP 433
PP+S + + R P P + P S P PL PP P A A PP P P
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Query: 434 STSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYV 469
S SP + P++ PP P V
Sbjct: 804 PASFPGQAPFSP-----SASLPMSPLATPPPQAPPV 834
Score = 103 bits (257), Expect = 4e-22
Identities = 119/405 (29%), Positives = 154/405 (38%), Gaps = 63/405 (15%)
Query: 126 PPLLPPGGRSTSAKPF-SPPSGPGRFPVP-SPGHRSGPPEPQRNRMPPPRPDVGSKPDSI 183
PP PP S + SPP P P P +P + PP PP P +
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----LQAPPSPPASPPLSPL 645
Query: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQP--SPGPTPPPFPGNRGTALGGGSIRQSPLS 241
P P P + P P P Q SP +PP P + Q+P S
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-------QAPPS 698
Query: 242 SSSPFSNRPPLPP-TPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
++P PP PP +P + PPP PP P + VPP PP + +TP P
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ---VPPSPPASPPMSPSATPPP 755
Query: 301 SASS--QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR----- 353
APP PPS P P+ P + + P + +PP PG+
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 815
Query: 354 SGPLPPPPSERPPPPVRDPPGRSGPL---PPPPPVSRNGSTSRALPATPQLPSRSGVDSP 410
S LP P PPP + PP + PL PP PP S T +A P+ P G D+
Sbjct: 816 SASLPMSPLATPPP--QAPPVLAAPLLQVPPSPPAS---PTLQA----PRRPPTPGPDTS 866
Query: 411 RSGPRPPLPPDRPSAGAPPPPP---PSTSIRN----GFQDSPCEDEWESRFYFHPISDLP 463
SGPR L A PPPPP PS+++ G S E R Y D
Sbjct: 867 VSGPRLTL----ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-----DSG 917
Query: 464 P-------PEPYVQTTKSYPSKLARNESRSGSNRRERGAP-PLPP 500
P P P + +P+ +R + + R GAP P PP
Sbjct: 918 PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962
Score = 93.6 bits (231), Expect = 4e-19
Identities = 152/643 (23%), Positives = 196/643 (30%), Gaps = 167/643 (25%)
Query: 2 PVPP-PPAPPPPPTFALANT--------EKPTLNKTEQAGRNALLSDISKGKKLKKTVTN 52
P PP P PPPP T A KP + G + + + T+
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86
Query: 53 DRSAPILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGL----------GG 102
R+ G G G G G G G GL G
Sbjct: 87 SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146
Query: 103 LFQAGMPKLRSTANRDNDSG---GSRPPLLPPGGRST-----------SAKPFSPPSGPG 148
+A S R + SG G+ P + R+ SA+P P GP
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 149 RFPVPSPGHRSGPPEPQRNRMPPPRPDVGS---KPDSIPPPVPSTP--RPIQSSPHNRGS 203
+ + H + P P R RP G +P S +TP P +S P RG+
Sbjct: 207 KSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 204 PPVPGGPRQPSPGPT-----PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258
P P P QP P P P + A G + SPL++ SP + P P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322
Query: 259 ALDDKPP--PPPPPVGNR-----------PSIHREAVPPPPPQNNKPPVPSTPRPSA--- 302
A P PP PP+ PS+ PP P + PP +TP A
Sbjct: 323 AATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS 382
Query: 303 ----------------SSQAPPPP-----------------------------------P 311
S QAPP P
Sbjct: 383 LQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT 442
Query: 312 PPSRPGP-PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP------------ 358
PSRP PP P P P SLS + PL SP PL
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502
Query: 359 -----------------PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP--ATP 399
PP + PP + PP + P PPP+ + S P TP
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL-QTASAPLTTPHLETP 561
Query: 400 QLPSRSGVDSPRSGPRPPLPPDRPSAGA-PPPPPPSTSIRNGFQDSPCEDEWESRFYFHP 458
P+ + +P S P PP+ PS+ A PPP P Q P P
Sbjct: 562 PCPAPCPLQAPPSPLTTP-PPETPSSIATPPPQAPPALASPPLQGLPSP----------P 610
Query: 459 ISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPI 501
+S L P P + P A + +PPL P+
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPA--------SPPLSPL 645
Score = 92.4 bits (228), Expect = 8e-19
Identities = 119/404 (29%), Positives = 143/404 (35%), Gaps = 105/404 (25%)
Query: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP-SPGHRSGPPEPQRNRMPPPRPDVGSK 179
SG P+ PP +T PPS P P+P +P S PP Q PP P +
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 180 PDSIPPPVPSTPR-----PIQSSPHNRGSPPVPG-------------------------- 208
P PP+ + P PIQ PH+ SP +
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQV-PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS 428
Query: 209 ----GPRQ-------PS-PGPTPPPFPGNRG-----------TALGGG-SIRQSPL---- 240
PRQ PS P TPP P + T+L S SPL
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488
Query: 241 ----------SSSSPFSN--RPPLPPTPSRALDDKPPPPP----PPVGNRPSIHREAVPP 284
S +P S+ PPL S A PP PP+ N PS+ P
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL-----AP 543
Query: 285 PPPQNNKPPV-------PSTPRPSASSQAPPPP---PPPSRPG----PPPLPPSSSGNDE 330
PP Q P+ P P P QAPP P PPP P PPP P + +
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAP-CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
LP LS ++ PP P + LPP + PP P PP PL P P + N
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLA--LPPLQA--PPSPPASPP--LSPLATPSPQAPNAL 656
Query: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
L A P V +P S P PP PSA P PPS
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPFSPPAS--PPVSPSATPPSQAPPS 698
Score = 54.7 bits (130), Expect = 2e-07
Identities = 87/348 (25%), Positives = 113/348 (32%), Gaps = 87/348 (25%)
Query: 226 RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP-----------VGNR 274
R A G + R + + RPP P +PPPP P VG +
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSP--------RPPPPVTPAALRVLGAAGAVGRK 56
Query: 275 PSIHR----------EAVPPPPPQNNKPPVPSTP--RPSASSQAP-PPPPPPSRPGPPPL 321
P R E+ P P + P RP AS + PP + PGP
Sbjct: 57 PLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
Query: 322 PPSSSGNDETPRLPQRNLSLSSS----------------------------TPPLPSP-- 351
P +SG L Q+ L +S+ TP PSP
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 352 -------GRSGPLP-PPPSERPPPPVRDP------PGRSGPLPPPPPVSRNGSTSRAL-- 395
G LP P PS RP PP P P P R S L
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 396 PATPQL-PSRSGVDSP-RSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESR 453
PA+ L S + + SP RSGP P P+ + P P ++R P +D +
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA- 295
Query: 454 FYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPI 501
P+S P P TK+ P N + PP PP+
Sbjct: 296 --LGPLSSSPLATPSPSGTKARPVPPPDN----AATPLPATLPPSPPL 337
Score = 29.6 bits (65), Expect = 6.7
Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 8/90 (8%)
Query: 2 PVPPPPAP------PPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRS 55
P PAP P P T + ++ + A L ++ G V + S
Sbjct: 981 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLS 1040
Query: 56 APILDKPKGAGAGGGGGGFGG--GGGFGGG 83
+L AGG GGG GG GGG GG
Sbjct: 1041 RTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 1070
Score = 29.3 bits (64), Expect = 8.7
Identities = 14/25 (56%), Positives = 14/25 (56%)
Query: 65 AGAGGGGGGFGGGGGFGGGGGGGGG 89
A A G GG GGG G GGG GG
Sbjct: 1046 AAAEGAAGGSGGGPGGAEGGGVTGG 1070
Score = 29.3 bits (64), Expect = 8.7
Identities = 13/26 (50%), Positives = 13/26 (50%)
Query: 75 GGGGGFGGGGGGGGGGSFGGGGPPGL 100
G GG GGG GG GG GG L
Sbjct: 1050 GAAGGSGGGPGGAEGGGVTGGARAAL 1075
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 108 bits (271), Expect = 9e-24
Identities = 103/324 (31%), Positives = 123/324 (37%), Gaps = 68/324 (20%)
Query: 148 GRFPVP-SPGHRSGP--------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
G PVP S G SGP P P PP P + S S PP + S P +S P
Sbjct: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS--ESRP 378
Query: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT--P 256
++ PGGP P P P P G GG ++ +P P+ PP P P
Sbjct: 379 YHGMHGGGPGGP-GGGPHSFPHPLPSLTG-GHGGHPMQHNPNGPPPPWMQPPPPPMNQGP 436
Query: 257 SRALDDKPPP------------------------PPPPVGNRPSIHREAVPPPPPQNNKP 292
PPP PPPP+G P PPPPP P
Sbjct: 437 HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP------PPPPPSGQPP 490
Query: 293 PVPSTPRP--SASSQAPPPPPPP--SRPGPPPLP--------PSSSGNDETPRLPQRNLS 340
P PS P P Q PPPPPPP S PLP +S+G P Q+ +
Sbjct: 491 PPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAA 550
Query: 341 LSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT-P 399
++S G +P PP +PP PPG P PPPPP GS +P
Sbjct: 551 AAASPGAPQMQGNPTMVPLPPGVQPPL----PPGAPPPPPPPPP----GSAGMMIPPRGG 602
Query: 400 QLPSRSGVDSPRSGPRPPLPPDRP 423
PS D PR P LP +P
Sbjct: 603 DGPSHESEDFPR--PLVTLPGRQP 624
Score = 83.6 bits (205), Expect = 4e-16
Identities = 97/348 (27%), Positives = 115/348 (33%), Gaps = 98/348 (28%)
Query: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP-----GPTPP-PFPG 224
P VGS P+ S PRP ++P N PP Q P GP+ P+ G
Sbjct: 324 PVPASVGSTSGPATTPLASAPRP--AAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
Query: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPS----RALDDKPPPPPPPVGNRPSIHRE 280
G GG P S PLP + P PPPP
Sbjct: 382 MHGGGPGG--------PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ------- 426
Query: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP---SSSGNDETPRLPQR 337
PPPPP N P PP GPPP+ S+ RL Q
Sbjct: 427 --PPPPPMNQGPH------------------PPGHHGPPPMDQYLGSTPVGSGVYRLHQ- 465
Query: 338 NLSLSSSTPPLPSPGRSGPLPPPPS--ERPPPPVRDPP---GRSGPLPPPPPVSRNGST- 391
P P G P PPPPS PPP PP + P PPPPP S S+
Sbjct: 466 ----GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST 521
Query: 392 -----------------------------SRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
+ A P PQ+ + G +PPLPP
Sbjct: 522 PLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP-- 579
Query: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDE---WESRFYFHPISDLPPPEP 467
GAPPPPPP G P + ES + P+ LP +P
Sbjct: 580 ---GAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQP 624
Score = 72.8 bits (177), Expect = 7e-13
Identities = 102/398 (25%), Positives = 123/398 (30%), Gaps = 145/398 (36%)
Query: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
P P PPPP + + P +N S P +
Sbjct: 346 PAAPANNPPPPSLMSTTQSRPPWMN----------------------------SGPSESR 377
Query: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121
P + G G G GG GGG SF P GG G P + N +
Sbjct: 378 P-----------YHGMHGGGPGGPGGGPHSFPHPLPSLTGG--HGGHPM------QHNPN 418
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQ---------------- 165
G P + PP PP G P PGH PP Q
Sbjct: 419 GPPPPWMQPP----------PPPMNQGPHP---PGHHGPPPMDQYLGSTPVGSGVYRLHQ 465
Query: 166 -RNRMPPP----RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220
+ MPPP P P PPP PS P P + PP P P TP
Sbjct: 466 GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPP--PSSSMASSTPL 523
Query: 221 PFPGN---RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277
P+ N T+ G GSI PP + P P + P++
Sbjct: 524 PWQQNTTTTTTSAGTGSI-----------------PPWQQQQAAAAASPGAPQMQGNPTM 566
Query: 278 HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQR 337
VP PP +PP+P APPPPPPP PP S+G
Sbjct: 567 ----VPLPP--GVQPPLP--------PGAPPPPPPP--------PPGSAG---------- 594
Query: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGR 375
+ P R G P SE P P+ PGR
Sbjct: 595 ----------MMIPPRGGDGPSHESEDFPRPLVTLPGR 622
Score = 29.3 bits (64), Expect = 8.7
Identities = 38/130 (29%), Positives = 44/130 (33%), Gaps = 22/130 (16%)
Query: 97 PPGLGGLFQAGMPKLRSTANRDNDSG-GSRPP--------LLPPGGRSTSAKPFSPPSGP 147
PP +P ++T +G GS PP PG P P P
Sbjct: 512 PPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP 571
Query: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP 207
G P PG PP PPP P GS IPP P +S R +P
Sbjct: 572 GVQPPLPPG---APPP------PPP-PPPGSAGMMIPPRGGDGPSH-ESEDFPRPLVTLP 620
Query: 208 GGPRQPSPGP 217
G RQP P
Sbjct: 621 G--RQPQQRP 628
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 104 bits (260), Expect = 2e-22
Identities = 78/228 (34%), Positives = 93/228 (40%), Gaps = 54/228 (23%)
Query: 210 PRQPSPGPTPP--PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267
P PS P PP P PG+ GT + PP P+ PPPP
Sbjct: 565 PSVPSRAPVPPAPPLPGDSGTII----------------------PPPPAPGDSTTPPPP 602
Query: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR-PSASSQAPPPPPPPSRPGPPPLP-PSS 325
PPP PPPPP + S P P ++ +PPPP PPP P P
Sbjct: 603 PPP-----------PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 651
Query: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
G LP ++ PP P PG S +PP PPPP+ PG +G PPPPP+
Sbjct: 652 VGIPSPSSLP----GGTAIPPPPPLPG-SARIPP-----PPPPL---PGSAGIPPPPPPL 698
Query: 386 SRNGSTSRALPATPQLPSRSGVDSPRSGP-RPPLPPDRPSAGAPPPPP 432
P P LP G+ P P P +PP P G PPPPP
Sbjct: 699 PGEAGMP---PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743
Score = 98.2 bits (243), Expect = 2e-20
Identities = 73/201 (36%), Positives = 83/201 (41%), Gaps = 42/201 (20%)
Query: 253 PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP 312
P PSRA P PP PP+ P +PPPP + P P PPPPPP
Sbjct: 565 PSVPSRA----PVPPAPPL---PGDSGTIIPPPPAPGDSTTPPPPP--------PPPPPP 609
Query: 313 PSRPG------PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS----------PGRSGP 356
P PG PP LP G +P P + PPLP PG +
Sbjct: 610 PPLPGGVCISSPPSLP---GGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 666
Query: 357 LPPPP---SERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
PPPP S R PPP PG +G PPPPP+ P P LP G+ P
Sbjct: 667 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP---PPPPPLPGGPGIPPPPPF 723
Query: 414 PRPP-LPPDRPSAGAPPPPPP 433
P P +PP P G PPPPP
Sbjct: 724 PGGPGIPPPPPGMGM-PPPPP 743
Score = 97.8 bits (242), Expect = 2e-20
Identities = 76/208 (36%), Positives = 84/208 (40%), Gaps = 31/208 (14%)
Query: 143 PPSGPGRFPVPSPGHRSGPPEPQRNRM---PPPRPDVGSKPDSIPPPVPSTPRPIQSSPH 199
PPS P R PVP PP P + PPP P + P PPP P P P+
Sbjct: 564 PPSVPSRAPVPP-----APPLPGDSGTIIPPPPAPGDSTTPPP-PPPPPPPPPPLPGGVC 617
Query: 200 NRGSPPVPGG----PRQPSPG----PTPPPFPGNRG----TALGGGSIRQSPLSSSSPFS 247
P +PGG P P G P PPP P G ++L GG+ P P S
Sbjct: 618 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP--PPLPGS 675
Query: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307
R P PP P PPPPPP G +PPPPP P P P P P
Sbjct: 676 ARIPPPPPPLPGSAGIPPPPPPLPGEA------GMPPPPPP--LPGGPGIPPPPPFPGGP 727
Query: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLP 335
PPPP G PP PP G P LP
Sbjct: 728 GIPPPPPGMGMPPPPPFGFGVPAAPVLP 755
Score = 95.5 bits (236), Expect = 1e-19
Identities = 83/231 (35%), Positives = 97/231 (41%), Gaps = 46/231 (19%)
Query: 182 SIPPPVPS-TPRPIQSSPHNRGSPPVPGG-----PRQPSPGP--T--PPPFPGNRGTALG 231
++PP VPS P P +PP+PG P P+PG T PPP P L
Sbjct: 562 TVPPSVPSRAPVP--------PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 613
Query: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG-NRPSIHR----EAVPPPP 286
GG SP S + PP P + + PPPPP P G PS A+PPPP
Sbjct: 614 GGVCISSPPSLPGGTAISPPPPLSGDATI---PPPPPLPEGVGIPSPSSLPGGTAIPPPP 670
Query: 287 --PQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344
P + + P P P P ++ PPPPP P G PP PP G P
Sbjct: 671 PLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP------------ 718
Query: 345 TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRAL 395
PP P PG G PPPP PPP PP G P PV G T + L
Sbjct: 719 -PPPPFPGGPGIPPPPPGMGMPPP---PPFGFG--VPAAPVLPFGLTPKKL 763
Score = 92.4 bits (228), Expect = 8e-19
Identities = 71/209 (33%), Positives = 81/209 (38%), Gaps = 41/209 (19%)
Query: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE-PQRNRMPPPRPDVGS 178
DSG PP PG +T P PP P P+P S PP P + PP P G
Sbjct: 582 DSGTIIPPPPAPGDSTTPPPPPPPPPPPP--PLPGGVCISSPPSLPGGTAISPPPPLSGD 639
Query: 179 KPDSIPPPVPS-----TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
PPP+P +P + PP+PG R P P PPP PG+ G
Sbjct: 640 ATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP---PPPPPLPGSAGIP---- 692
Query: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
PP PP P A PPPPPP+ P I PPPPP P
Sbjct: 693 ----------------PPPPPLPGEA---GMPPPPPPLPGGPGI-----PPPPPFPGGPG 728
Query: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLP 322
+P P P PPPP P P LP
Sbjct: 729 IP--PPPPGMGMPPPPPFGFGVPAAPVLP 755
Score = 80.5 bits (197), Expect = 3e-15
Identities = 58/158 (36%), Positives = 71/158 (44%), Gaps = 40/158 (25%)
Query: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
AS A PPS P P+PP+ P LP + ++ PP P+PG S PPPP
Sbjct: 554 ASLSAAAITVPPSVPSRAPVPPA-------PPLPGDSGTI---IPPPPAPGDSTTPPPPP 603
Query: 362 SERPPPP-------VRDPPGRSG--PLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
PPPP + PP G + PPPP+S + + +P P LP G+ SP S
Sbjct: 604 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDAT----IPPPPPLPEGVGIPSPSS 659
Query: 413 GPR----------------PPLPPDRP-SAGAPPPPPP 433
P PP PP P SAG PPPPPP
Sbjct: 660 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP 697
Score = 57.0 bits (136), Expect = 4e-08
Identities = 46/138 (33%), Positives = 56/138 (40%), Gaps = 34/138 (24%)
Query: 330 ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP------SERPPPPV----RDPPGRSGPL 379
E + +LS ++ T P P R+ P PP + PPPP PP P
Sbjct: 547 EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP 606
Query: 380 PPPPPV----------SRNGSTS----------RALPATPQLPSRSGVDSPRSGPR---- 415
PPPPP+ S G T+ +P P LP G+ SP S P
Sbjct: 607 PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 666
Query: 416 PPLPPDRPSAGAPPPPPP 433
PP PP SA PPPPPP
Sbjct: 667 PPPPPLPGSARIPPPPPP 684
Score = 43.1 bits (100), Expect = 6e-04
Identities = 61/212 (28%), Positives = 73/212 (34%), Gaps = 49/212 (23%)
Query: 2 PVPPPPAPPPPPTF--ALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPIL 59
P PPPP PPPPP + + P+L G A IS L T P+
Sbjct: 599 PPPPPPPPPPPPPLPGGVCISSPPSL-----PGGTA----ISPPPPLSGDATIPPPPPL- 648
Query: 60 DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDN 119
P+G G GG PP L G + P
Sbjct: 649 --PEGVGIPSPSSLPGG---------------TAIPPPPPLPGSARIPPPPPPLPG---- 687
Query: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
S G PP PP + P PP PG +P P PP P +PPP P +G
Sbjct: 688 -SAGIPPP--PPPLPGEAGMPPPPPPLPGGPGIPPP-----PPFPGGPGIPPPPPGMGMP 739
Query: 180 PDSIPPP----VPSTP-RPIQSSPHNRGSPPV 206
P PPP VP+ P P +P P V
Sbjct: 740 P---PPPFGFGVPAAPVLPFGLTPKKLYKPEV 768
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 104 bits (260), Expect = 2e-22
Identities = 78/228 (34%), Positives = 93/228 (40%), Gaps = 54/228 (23%)
Query: 210 PRQPSPGPTPP--PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267
P PS P PP P PG+ GT + PP P+ PPPP
Sbjct: 574 PSVPSRAPVPPAPPLPGDSGTII----------------------PPPPAPGDSTTPPPP 611
Query: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR-PSASSQAPPPPPPPSRPGPPPLP-PSS 325
PPP PPPPP + S P P ++ +PPPP PPP P P
Sbjct: 612 PPP-----------PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 660
Query: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
G LP ++ PP P PG S +PP PPPP+ PG +G PPPPP+
Sbjct: 661 VGIPSPSSLP----GGTAIPPPPPLPG-SARIPP-----PPPPL---PGSAGIPPPPPPL 707
Query: 386 SRNGSTSRALPATPQLPSRSGVDSPRSGP-RPPLPPDRPSAGAPPPPP 432
P P LP G+ P P P +PP P G PPPPP
Sbjct: 708 PGEAGMP---PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 752
Score = 98.2 bits (243), Expect = 2e-20
Identities = 73/201 (36%), Positives = 83/201 (41%), Gaps = 42/201 (20%)
Query: 253 PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP 312
P PSRA P PP PP+ P +PPPP + P P PPPPPP
Sbjct: 574 PSVPSRA----PVPPAPPL---PGDSGTIIPPPPAPGDSTTPPPPP--------PPPPPP 618
Query: 313 PSRPG------PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS----------PGRSGP 356
P PG PP LP G +P P + PPLP PG +
Sbjct: 619 PPLPGGVCISSPPSLP---GGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 675
Query: 357 LPPPP---SERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
PPPP S R PPP PG +G PPPPP+ P P LP G+ P
Sbjct: 676 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP---PPPPPLPGGPGIPPPPPF 732
Query: 414 PRPP-LPPDRPSAGAPPPPPP 433
P P +PP P G PPPPP
Sbjct: 733 PGGPGIPPPPPGMGM-PPPPP 752
Score = 97.8 bits (242), Expect = 2e-20
Identities = 76/208 (36%), Positives = 84/208 (40%), Gaps = 31/208 (14%)
Query: 143 PPSGPGRFPVPSPGHRSGPPEPQRNRM---PPPRPDVGSKPDSIPPPVPSTPRPIQSSPH 199
PPS P R PVP PP P + PPP P + P PPP P P P+
Sbjct: 573 PPSVPSRAPVPP-----APPLPGDSGTIIPPPPAPGDSTTPPP-PPPPPPPPPPLPGGVC 626
Query: 200 NRGSPPVPGG----PRQPSPG----PTPPPFPGNRG----TALGGGSIRQSPLSSSSPFS 247
P +PGG P P G P PPP P G ++L GG+ P P S
Sbjct: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP--PPLPGS 684
Query: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307
R P PP P PPPPPP G +PPPPP P P P P P
Sbjct: 685 ARIPPPPPPLPGSAGIPPPPPPLPGEA------GMPPPPPP--LPGGPGIPPPPPFPGGP 736
Query: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLP 335
PPPP G PP PP G P LP
Sbjct: 737 GIPPPPPGMGMPPPPPFGFGVPAAPVLP 764
Score = 95.5 bits (236), Expect = 1e-19
Identities = 83/231 (35%), Positives = 97/231 (41%), Gaps = 46/231 (19%)
Query: 182 SIPPPVPS-TPRPIQSSPHNRGSPPVPGG-----PRQPSPGP--T--PPPFPGNRGTALG 231
++PP VPS P P +PP+PG P P+PG T PPP P L
Sbjct: 571 TVPPSVPSRAPVP--------PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 622
Query: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG-NRPSIHR----EAVPPPP 286
GG SP S + PP P + + PPPPP P G PS A+PPPP
Sbjct: 623 GGVCISSPPSLPGGTAISPPPPLSGDATI---PPPPPLPEGVGIPSPSSLPGGTAIPPPP 679
Query: 287 --PQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344
P + + P P P P ++ PPPPP P G PP PP G P
Sbjct: 680 PLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP------------ 727
Query: 345 TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRAL 395
PP P PG G PPPP PPP PP G P PV G T + L
Sbjct: 728 -PPPPFPGGPGIPPPPPGMGMPPP---PPFGFG--VPAAPVLPFGLTPKKL 772
Score = 92.4 bits (228), Expect = 8e-19
Identities = 71/209 (33%), Positives = 81/209 (38%), Gaps = 41/209 (19%)
Query: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE-PQRNRMPPPRPDVGS 178
DSG PP PG +T P PP P P+P S PP P + PP P G
Sbjct: 591 DSGTIIPPPPAPGDSTTPPPPPPPPPPPP--PLPGGVCISSPPSLPGGTAISPPPPLSGD 648
Query: 179 KPDSIPPPVPS-----TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
PPP+P +P + PP+PG R P P PPP PG+ G
Sbjct: 649 ATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP---PPPPPLPGSAGIP---- 701
Query: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
PP PP P A PPPPPP+ P I PPPPP P
Sbjct: 702 ----------------PPPPPLPGEA---GMPPPPPPLPGGPGI-----PPPPPFPGGPG 737
Query: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLP 322
+P P P PPPP P P LP
Sbjct: 738 IP--PPPPGMGMPPPPPFGFGVPAAPVLP 764
Score = 80.5 bits (197), Expect = 3e-15
Identities = 58/158 (36%), Positives = 71/158 (44%), Gaps = 40/158 (25%)
Query: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
AS A PPS P P+PP+ P LP + ++ PP P+PG S PPPP
Sbjct: 563 ASLSAAAITVPPSVPSRAPVPPA-------PPLPGDSGTI---IPPPPAPGDSTTPPPPP 612
Query: 362 SERPPPP-------VRDPPGRSG--PLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
PPPP + PP G + PPPP+S + + +P P LP G+ SP S
Sbjct: 613 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDAT----IPPPPPLPEGVGIPSPSS 668
Query: 413 GPR----------------PPLPPDRP-SAGAPPPPPP 433
P PP PP P SAG PPPPPP
Sbjct: 669 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP 706
Score = 57.0 bits (136), Expect = 4e-08
Identities = 46/138 (33%), Positives = 56/138 (40%), Gaps = 34/138 (24%)
Query: 330 ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP------SERPPPPV----RDPPGRSGPL 379
E + +LS ++ T P P R+ P PP + PPPP PP P
Sbjct: 556 EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP 615
Query: 380 PPPPPV----------SRNGSTS----------RALPATPQLPSRSGVDSPRSGPR---- 415
PPPPP+ S G T+ +P P LP G+ SP S P
Sbjct: 616 PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 675
Query: 416 PPLPPDRPSAGAPPPPPP 433
PP PP SA PPPPPP
Sbjct: 676 PPPPPLPGSARIPPPPPP 693
Score = 43.1 bits (100), Expect = 6e-04
Identities = 61/212 (28%), Positives = 73/212 (34%), Gaps = 49/212 (23%)
Query: 2 PVPPPPAPPPPPTF--ALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPIL 59
P PPPP PPPPP + + P+L G A IS L T P+
Sbjct: 608 PPPPPPPPPPPPPLPGGVCISSPPSL-----PGGTA----ISPPPPLSGDATIPPPPPL- 657
Query: 60 DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDN 119
P+G G GG PP L G + P
Sbjct: 658 --PEGVGIPSPSSLPGG---------------TAIPPPPPLPGSARIPPPPPPLPG---- 696
Query: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSK 179
S G PP PP + P PP PG +P P PP P +PPP P +G
Sbjct: 697 -SAGIPPP--PPPLPGEAGMPPPPPPLPGGPGIPPP-----PPFPGGPGIPPPPPGMGMP 748
Query: 180 PDSIPPP----VPSTP-RPIQSSPHNRGSPPV 206
P PPP VP+ P P +P P V
Sbjct: 749 P---PPPFGFGVPAAPVLPFGLTPKKLYKPEV 777
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 104 bits (260), Expect = 2e-22
Identities = 87/262 (33%), Positives = 99/262 (37%), Gaps = 59/262 (22%)
Query: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEPQRNRMPPPRPDVGSKP 180
GGS P GGR P + P G RFP P+ PG GPP P PPRP +G
Sbjct: 190 GGSSRAAFPQGGRGRGRFPGAVPGGD-RFPGPAGPG---GPPPPFPAGQTPPRPPLGPPG 245
Query: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
PP P P P Q P PP+ G P + P P FPG
Sbjct: 246 ---PPGPPGPPPPGQVLP-----PPLAGPPNRGDRPPPPVLFPGQP-------------- 283
Query: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
P PP PP P P PPPP G PPPP PP P P
Sbjct: 284 FGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQG-----------PPPPPGPFPPRPPGPLG 332
Query: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP----LPSPGRSGP 356
+ APPP P PG PP P +++ + PP +P+ GP
Sbjct: 333 PPLTLAPPPHLPGPPPGAPP--------------PAPHVNPAFFPPPTNSGMPTSDSRGP 378
Query: 357 LPPPPSERPPPPVR---DPPGR 375
P P RPPP R PPGR
Sbjct: 379 PPTDPYGRPPPYDRGDYGPPGR 400
Score = 99.0 bits (245), Expect = 9e-21
Identities = 93/303 (30%), Positives = 110/303 (36%), Gaps = 66/303 (21%)
Query: 25 LNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGG 84
L K E G+N +++ +K + L + R + G G G GG F GG
Sbjct: 144 LPKRELHGQNPVVTPCNK-QFLSQFEMQSRKTTQSGQMSGEGKAGPPGG-SSRAAFPQGG 201
Query: 85 GGGG---GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF 141
G G G GG PG G GG PP P G++ P
Sbjct: 202 RGRGRFPGAVPGGDRFPGPAG------------------PGGPPPPF--PAGQTPPRPPL 241
Query: 142 SPPSGPGRFPVPSPGHRSGPP---EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
PP PG P PG PP P R PPP +P PP P P P
Sbjct: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP----- 296
Query: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258
PPVPG P PGP PP +Q P PF RPP P P
Sbjct: 297 ----PPPVPG--YGPPPGPPPP---------------QQGPPPPPGPFPPRPPGPLGPPL 335
Query: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK---PPVPSTPRPSASSQAPPPPPPPSR 315
L P P PP G PPP P N PP ++ P++ S+ PPP P R
Sbjct: 336 TLAPPPHLPGPPPG---------APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386
Query: 316 PGP 318
P P
Sbjct: 387 PPP 389
Score = 88.6 bits (218), Expect = 1e-17
Identities = 84/259 (32%), Positives = 98/259 (37%), Gaps = 70/259 (27%)
Query: 185 PPVPSTPRPIQSSPHNRGSPP--VPGGPRQPSP---GPTPPPFPGNRGTALGGGSIRQSP 239
PP S+ RG P VPGG R P P G PPPFP G + + P
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPA-------GQTPPRPP 240
Query: 240 LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPP------PQNNKP- 292
L P PP PP P + L PPP+ P+ R PPPP P P
Sbjct: 241 LGPPGPPG--PPGPPPPGQVL-------PPPLAGPPN--RGDRPPPPVLFPGQPFGQPPL 289
Query: 293 -PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP 351
P+P P P PPP PPP + GPPP P
Sbjct: 290 GPLPPGPPPPVPGYGPPPGPPPPQQGPPP-----------------------------PP 320
Query: 352 GRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPR 411
G P PP P PP + PP GP P PP + + + PA P+ SG+ P
Sbjct: 321 GPFPPRPPGPL-GPPLTLAPPPHLPGPPPGAPPPAPHVN-----PAFFPPPTNSGM--PT 372
Query: 412 SGPRPPLPPDRPSAGAPPP 430
S R P P D G PPP
Sbjct: 373 SDSRGPPPTD--PYGRPPP 389
Score = 78.2 bits (191), Expect = 2e-14
Identities = 72/213 (33%), Positives = 80/213 (37%), Gaps = 55/213 (25%)
Query: 279 REAVPPPPPQNNKPPVPS----TPRPSASSQAPPPPP--PPSRPGPPPLPPSSSGNDETP 332
R P P ++ P P+ P P + Q PP PP PP PGPP PP
Sbjct: 204 RGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQV----- 258
Query: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLP--PPPPVSRNGS 390
LP PPL P G PPPP P P PP GPLP PPPPV G
Sbjct: 259 -LP----------PPLAGPPNRGDRPPPPVLFPGQPFGQPP--LGPLPPGPPPPVPGYGP 305
Query: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPP---DRPSAGAPPP---------PPPSTSIR 438
P P P + P GP PP PP P APPP PPP+ +
Sbjct: 306 -----PPGPPPPQQG--PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVN 358
Query: 439 NGFQDSPCEDEWESRFYFHPISDL---PPPEPY 468
F P P SD PP +PY
Sbjct: 359 PAFFPPPTNSGM-------PTSDSRGPPPTDPY 384
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 103 bits (256), Expect = 5e-22
Identities = 124/422 (29%), Positives = 148/422 (35%), Gaps = 69/422 (16%)
Query: 66 GAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSR 125
GA G G G G G G G G+ G GPPG G P LR T +D + G
Sbjct: 383 GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-----SVGAPGLRGTPGKDGERGEK- 436
Query: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
G S P P PG +P P + EP P +G+K D P
Sbjct: 437 ----GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAP 492
Query: 186 PVPSTPRPIQSSPHNRGSPPVPGGP--RQPSPGPTP-PPFPGNRGTA-LGGGSIRQSP-- 239
+P +P PP P GP + SPG P FPG +G A G S SP
Sbjct: 493 GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGD 552
Query: 240 --LSSSSPFSNRPPLPP-TPSRA--LDDKPPPPPPPVGNRPSIHREAVPP--PPPQNNKP 292
L + ++ PP PP P DK P P EA PP P P
Sbjct: 553 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAG 612
Query: 293 PVPSTPRPSA-------SSQAPPPPP----PPSRPGPPPL-------------------- 321
P S A Q P P PP PGPP
Sbjct: 613 PQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEG 672
Query: 322 PPSSSGNDETPRLPQRNLSLSSSTPPLP--SPGRSGP--LPPPPSERPPPPVRDPPGRSG 377
PP G P +P P P PG++G LP P R PP + G SG
Sbjct: 673 PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSG 732
Query: 378 PLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP-----SAGAPPPPP 432
P R S + LP LP + G D+ +GP+ P P P S G+P P
Sbjct: 733 -----APGPRGESGAMGLPGQEGLPGKDG-DTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 786
Query: 433 PS 434
PS
Sbjct: 787 PS 788
Score = 88.6 bits (218), Expect = 1e-17
Identities = 125/478 (26%), Positives = 154/478 (32%), Gaps = 100/478 (20%)
Query: 54 RSAPILDKPKGAGAGGGGGGFGGGGGFGGGGGGGG-GGSFGGGGPPGLGGLFQAGMPKLR 112
++AP L + G G G G G G G G G G G GL G G P +R
Sbjct: 240 KTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA--PGFPGVR 297
Query: 113 STANRDNDSGG-SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHR----SGPPEPQRN 167
+ G P L G A P PP PG + +P R GP + +
Sbjct: 298 GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGD 357
Query: 168 RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP----SPGPTPPP-- 221
P P + +P + P P+ P + G+P G P P +PGP+ PP
Sbjct: 358 PGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGS 417
Query: 222 --FPGNRGTALGGGSIRQSPLS----SSSPFSNR-----PPLPPTPSRALDDKP-----P 265
PG RGT G + + S P R P LP P + D +P P
Sbjct: 418 VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSP 477
Query: 266 PPPPPVGNRPSIHREAVPPPPPQNNK-------PPVPSTPRPSASSQA-------PPPPP 311
P P+G + +P P PP PS P S P P
Sbjct: 478 GLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 537
Query: 312 PPSR------------------------PGPPPLP--PSSSGNDETPRLPQR----NLSL 341
P R PGPP LP P G+ P P R
Sbjct: 538 PAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 597
Query: 342 SSSTPPLPS-PGRSGPL--------------------PPPPSERPPPPVRDPPGRSGPLP 380
+ P LP PG +GP P P PP PPG G
Sbjct: 598 EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 657
Query: 381 PPPPVSRNGSTSRALPATPQ----LPSRSGVDSPRSGPRPPLPPDRP-SAGAPPPPPP 433
P GS + P PQ LP G + P PP P AG P P P
Sbjct: 658 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP 715
Score = 82.4 bits (202), Expect = 9e-16
Identities = 142/551 (25%), Positives = 181/551 (32%), Gaps = 114/551 (20%)
Query: 6 PPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGA 65
PP PP P +K K + G ++GKK + P + P+G+
Sbjct: 565 PPGPPGLPGLPGFKGDKGVPGKPGREG--------TEGKKGEAGPPGLPGPPGIAGPQGS 616
Query: 66 -GAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLF-QAGMPKLRSTANRDNDSGG 123
G G G G G G G G G G GPPG G+ AG P ++ + ++ G
Sbjct: 617 QGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGP 676
Query: 124 SRPPLLP-----PGGRSTSAKPFSPPSGPGRFPVP----------------------SPG 156
P LP G KP PP PG+ P +PG
Sbjct: 677 QGPSGLPGIPGEEGKEGRDGKP-GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPG 735
Query: 157 HR--------------------SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQS 196
R +GP PQ + P P P S P PS +
Sbjct: 736 PRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKG 795
Query: 197 SPHNRGSPPVPG--GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP-FSNRPPLP 253
S GSP +PG GPR P P PG G P P F P
Sbjct: 796 SKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGV----------PGKPGEPGFKGERGDP 845
Query: 254 PTPSRALDDKPPPPPPPVGNRPSI--HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPP 311
DK PP P I H+ PQ +P P PP
Sbjct: 846 GIKG----DKGPPGGKGQPGDPGIPGHKGHTGLMGPQG----LPGENGPVG------PPG 891
Query: 312 PPSRPGPPPLPPSSSGNDETPRLPQRNLS---------LSSSTPPL---PSPGRSGPLPP 359
PP +PG P L S + RL Q L L + PP S GR GP
Sbjct: 892 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGP--- 948
Query: 360 PPSERPPPPVRDP-PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418
P PP +D PGR+GP+ P + G + P P+ G P L
Sbjct: 949 -----PGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPK--GERGAKGDPGAPGVGL 1001
Query: 419 PPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLP-PPEPYVQTTKSYPS 477
+ G P P ++G P + E+ HP LP PP P Q S +
Sbjct: 1002 RGEMGPPGIPGQPGEPGYAKDGLPGIP-GPQGETGPAGHP--GLPGPPGPPGQCDPSQCA 1058
Query: 478 KLARNESRSGS 488
A +R G+
Sbjct: 1059 YFASLAARPGN 1069
Score = 82.0 bits (201), Expect = 1e-15
Identities = 112/402 (27%), Positives = 139/402 (34%), Gaps = 62/402 (15%)
Query: 54 RSAPILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPG----LGGLFQAGMP 109
R +P L P G G G G G G G G G G GPPG G G P
Sbjct: 474 RGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFP 533
Query: 110 KLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF---SPPSGPGRFPVPS-PGHRSGPPEPQ 165
+ A RD S LL PG + AK PP PG +P G + P +P
Sbjct: 534 GPQGPAGRDGLSS-----LLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 588
Query: 166 RNRMPPPRPDVGSKPDSIP-PPVPSTPRPIQ---------SSPHNRGSPPVPGGPRQP-S 214
R + + G P +P PP + P+ Q ++G P VPG P +
Sbjct: 589 REGTEGKKGEAG--PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 646
Query: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274
PGP PG G A G P SP PP P PS P G
Sbjct: 647 PGP-----PGADGIAGAAG----PPGIQGSPGKEGPPGPQGPSGL--------PGIPGEE 689
Query: 275 PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
R+ P PP + K P P P ++ PP + P P SG P
Sbjct: 690 GKEGRDGKPGPPGEPGKAGEPGLPGPE-GARGPPGFKGHTGDSGAPGPRGESGAMGLP-- 746
Query: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSG----PLPPPPPVSRNGS 390
Q L PG+ G P + P P R PPG++G P P P +
Sbjct: 747 GQEGL-----------PGKDGDTGPTGPQGPQGP-RGPPGKNGSPGSPGEPGPSGTPGQK 794
Query: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
S+ +P LP G P P P + P P
Sbjct: 795 GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP 836
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 103 bits (256), Expect = 5e-22
Identities = 78/275 (28%), Positives = 108/275 (39%), Gaps = 40/275 (14%)
Query: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
PP PP + P PPS P + +P +S PP ++P P + P S+
Sbjct: 765 PPPPPPQQQQQPPPPPPPPSMPQQ---AAPAMKSSPPPFIATQVPVLEPQL---PGSVFD 818
Query: 186 PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG-----------------PTPPPFPGNRGT 228
P+ +PI P P +P P +P P P P NR
Sbjct: 819 PIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAA 878
Query: 229 ALGGGSIRQ---SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA---V 282
AL R SP + +P +PP+ P L+D+ PP PP + ++ + V
Sbjct: 879 ALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKV 938
Query: 283 PPPPP--------QNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPR- 333
PP P PP+P P PS Q PPPP P P P PP + PR
Sbjct: 939 QPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPP--PPPQPQPPPQQQHQPPPRP 996
Query: 334 LPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
+ + + S+ P P P PPP ++PPPP
Sbjct: 997 VHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPP 1031
Score = 82.0 bits (201), Expect = 1e-15
Identities = 76/257 (29%), Positives = 98/257 (38%), Gaps = 51/257 (19%)
Query: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP----PPPPPSRPGPPPL 321
PPPPP ++ PPPPPQ + P P P PS QA P PPP P L
Sbjct: 757 PPPPP--------QQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVL 808
Query: 322 PPSSSGNDETPRLPQRNLSLSSSTPP---LPSPGRSGPLPPPPSERPPP-----PVRDPP 373
P G+ P + T P LP P LP PP PP V PP
Sbjct: 809 EPQLPGSVFDP--------IGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPP 860
Query: 374 GRSGPLPPPPPVSRNGSTSRALPATPQLP---SRSGVDSPRSGPRPPL--PPDRPSAGAP 428
LP P SR + + ALP P P S + +P P+PP+ PP
Sbjct: 861 ALHNALPQQP--SRPSNRAAALPPKPARPPAVSPALTQTPLL-PQPPMAQPPQVLLEDEE 917
Query: 429 PPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTK--SYPSKLARNESRS 486
PP PP TS+ + + Y + + PP P + + K S P
Sbjct: 918 PPAPPLTSM-------------QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHP 964
Query: 487 GSNRRERGAPPLPPIPR 503
++ + PP PP P+
Sbjct: 965 SVQQQLQQQPPPPPPPQ 981
Score = 59.7 bits (143), Expect = 6e-09
Identities = 61/226 (26%), Positives = 80/226 (35%), Gaps = 29/226 (12%)
Query: 126 PPLLPPGGRSTSAKPFSPPSGPGRF-PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP 184
PP PP + + PP P P+ H PP PQ + PP P G +P P
Sbjct: 975 PPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQ--PPHPPPGQQP---P 1029
Query: 185 PPVPSTPRPI---QSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLS 241
PP P+ P+ + SP + S P G + +P P P S QS
Sbjct: 1030 PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQM--------SQFQSLTH 1081
Query: 242 SSSPFSNRPPLPPTPSRALDDKPPP---------PPPPVGNRP-SIHREAVPPPPPQNNK 291
S P N P A +P P P + + P S PP P++ K
Sbjct: 1082 QSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIK 1141
Query: 292 PPV--PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
PV P P P PP + PPP P + P+ P
Sbjct: 1142 APVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTP 1187
Score = 51.6 bits (122), Expect = 2e-06
Identities = 47/167 (28%), Positives = 63/167 (37%), Gaps = 26/167 (15%)
Query: 291 KPPVPSTPRPSASS-----QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345
KP V + P + +S Q P P PPP + P P P TP L + ++
Sbjct: 190 KPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAV------TPDLIVQTPVMTVVP 243
Query: 346 P-PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPP----VSRNGSTSRAL----- 395
P PL +P P P PP P PV+ P P P V R T+
Sbjct: 244 PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI 303
Query: 396 ---PATPQLPSRSGVDSPRSGPRPPLPP--DRPSAGAPPPPPPSTSI 437
P+ P P + + R RP PP D P + P P S+ +
Sbjct: 304 HEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKV 350
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/169 (27%), Positives = 67/169 (39%), Gaps = 36/169 (21%)
Query: 269 PPVGNRPSIHREAVPPPP--PQNNKPPVPSTPRPSAS------------SQAPP-----P 309
P V P+ + + PP PQ N PPV +TP P + + PP P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
Query: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPP-- 367
PP P +P PPP P P+ Q + + ++TP P + G + P
Sbjct: 251 PPVPPQPQPPPAP--------APQPVQSHPPIIAATPQ-PVKTKKGVKRKADTTTPTTID 301
Query: 368 PVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP 416
P+ +PP LPP P ++ G R + P P + V + P P
Sbjct: 302 PIHEPPS----LPPEPKTTKLG--QRRESSRPVKPPKKDVPDSQQHPAP 344
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/182 (26%), Positives = 68/182 (37%), Gaps = 36/182 (19%)
Query: 190 TPRPIQSSPHNRGSPPVPGGPRQPSPGP-----TPPPFPGNRGTALGGGSIRQSPLSS-- 242
T +P S+ N P + P P P TP PFP A+ I Q+P+ +
Sbjct: 188 TAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP-----AVTPDLIVQTPVMTVV 242
Query: 243 -SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301
P PP+PP +P PPP P P P Q++ P + +TP+P
Sbjct: 243 PPQPLQTPPPVPP--------QPQPPPAPA------------PQPVQSHPPIIAATPQPV 282
Query: 302 ASSQA---PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
+ + P+ P PPS +T +L QR S PP S P
Sbjct: 283 KTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHP 342
Query: 359 PP 360
P
Sbjct: 343 AP 344
Score = 43.1 bits (100), Expect = 6e-04
Identities = 47/181 (25%), Positives = 60/181 (33%), Gaps = 44/181 (24%)
Query: 147 PGRFPVPSPGHRSGPPEPQRNRMPPP------------RPD----------VGSKPDSIP 184
PG VP+ S PP+ Q + PP PD V +P P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
Query: 185 PPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSS 244
PPVP P+P P PV P P TP P +G + + +
Sbjct: 251 PPVPPQPQP----PPAPAPQPVQSHP--PIIAATPQPVKTKKGVKRKADTTTPTTI---D 301
Query: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS 304
P P LPP P +G R R P PP+ + P P P SS
Sbjct: 302 PIHEPPSLPPEPKTT----------KLGQRRESSR---PVKPPKKDVPDSQQHPAPEKSS 348
Query: 305 Q 305
+
Sbjct: 349 K 349
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/210 (26%), Positives = 76/210 (36%), Gaps = 31/210 (14%)
Query: 125 RPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRM-----PPPRP----- 174
RP L P ST + PP G + P P PG + PP+P + + PR
Sbjct: 995 RPVHLQPMQFSTHIQQPPPPQGQ-QPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDP 1053
Query: 175 -DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG-GPR----QPSPGPTPPPFPGNRGT 228
G ++ P + +P+ Q SPP P+ + + P P +
Sbjct: 1054 YSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEE 1113
Query: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA---LDDKPPPPPPPVGNRPSIHREAVPPP 285
+ IR P S S PP P +A L +P P VG RP I
Sbjct: 1114 KIHSPIIRSEPFSPS--LRPEPPKHPESIKAPVHLPQRPEMKPVDVG-RPVIR------- 1163
Query: 286 PPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
PP+ N PP P P Q P P P +
Sbjct: 1164 PPEQNAPP-PGAPDKDKQKQEPKTPVAPKK 1192
Score = 38.5 bits (88), Expect = 0.014
Identities = 37/158 (23%), Positives = 53/158 (33%), Gaps = 30/158 (18%)
Query: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355
S S+ S + + P G ++ + + + P+P
Sbjct: 701 SESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPP 760
Query: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT-------------PQLP 402
P PPP PPPP + + P PPPPP S + A+ ++ PQLP
Sbjct: 761 PQQPPP---PPPPQQ----QQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
Query: 403 SRSGVDSPRSG--------PRPPLPPDRPSAGAPPPPP 432
V P P+P LPP P PP
Sbjct: 814 --GSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPP 849
Score = 34.3 bits (77), Expect = 0.27
Identities = 26/75 (34%), Positives = 28/75 (37%), Gaps = 8/75 (10%)
Query: 372 PPGRSGPLPPPPPVSRNGSTSRALPA-TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
PP P P PPPV +T PA TP L V +P PP P P P P
Sbjct: 205 PPQTQTPQPNPPPVQ---ATPHPFPAVTPDLI----VQTPVMTVVPPQPLQTPPPVPPQP 257
Query: 431 PPPSTSIRNGFQDSP 445
PP Q P
Sbjct: 258 QPPPAPAPQPVQSHP 272
Score = 30.4 bits (67), Expect = 3.9
Identities = 18/61 (29%), Positives = 24/61 (39%), Gaps = 6/61 (9%)
Query: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
PVPP P PPP P + P + T Q + KG K K T + + +
Sbjct: 252 PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKT------KKGVKRKADTTTPTTIDPIHE 305
Query: 62 P 62
P
Sbjct: 306 P 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.137 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,224,320
Number of Sequences: 37866
Number of extensions: 4541116
Number of successful extensions: 164694
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2281
Number of HSP's successfully gapped in prelim test: 2764
Number of HSP's that attempted gapping in prelim test: 20951
Number of HSP's gapped (non-prelim): 49465
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.