BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116256363 transmembrane protease, serine 13 [Homo sapiens] (567 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 1169 0.0 gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 278 7e-75 gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 277 2e-74 gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 277 2e-74 gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 263 4e-70 gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 261 1e-69 gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 243 3e-64 gi|33695155 hepsin [Homo sapiens] 231 2e-60 gi|4504481 hepsin [Homo sapiens] 231 2e-60 gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 217 2e-56 gi|223942069 enterokinase precursor [Homo sapiens] 213 5e-55 gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 211 2e-54 gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 208 1e-53 gi|58218970 protease, serine, 36 [Homo sapiens] 204 1e-52 gi|4503627 coagulation factor XI precursor [Homo sapiens] 201 2e-51 gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 200 3e-51 gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 199 4e-51 gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 199 6e-51 gi|21614531 testisin isoform 2 [Homo sapiens] 197 2e-50 gi|4506153 prostasin preproprotein [Homo sapiens] 196 4e-50 gi|5803197 testisin isoform 1 [Homo sapiens] 196 4e-50 gi|29244926 corin [Homo sapiens] 196 6e-50 gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 195 8e-50 gi|11415040 matriptase [Homo sapiens] 187 2e-47 gi|4506143 neurotrypsin precursor [Homo sapiens] 187 2e-47 gi|4505881 plasminogen [Homo sapiens] 185 8e-47 gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 185 8e-47 gi|68508970 tryptase beta 2 precursor [Homo sapiens] 184 1e-46 gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 184 2e-46 gi|13994276 marapsin [Homo sapiens] 183 3e-46 >gi|116256363 transmembrane protease, serine 13 [Homo sapiens] Length = 567 Score = 1169 bits (3023), Expect = 0.0 Identities = 567/567 (100%), Positives = 567/567 (100%) Query: 1 MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQAS 60 MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQAS Sbjct: 1 MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQAS 60 Query: 61 PAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVY 120 PAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVY Sbjct: 61 PAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVY 120 Query: 121 LVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVV 180 LVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVV Sbjct: 121 LVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVV 180 Query: 181 SLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYS 240 SLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYS Sbjct: 181 SLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYS 240 Query: 241 GSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLH 300 GSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLH Sbjct: 241 GSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLH 300 Query: 301 RSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQW 360 RSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQW Sbjct: 301 RSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQW 360 Query: 361 VLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRL 420 VLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRL Sbjct: 361 VLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRL 420 Query: 421 SKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKC 480 SKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKC Sbjct: 421 SKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKC 480 Query: 481 NDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNK 540 NDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNK Sbjct: 481 NDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNK 540 Query: 541 PGVYTKVTEVLPWIYSKMESEVRFRKS 567 PGVYTKVTEVLPWIYSKMESEVRFRKS Sbjct: 541 PGVYTKVTEVLPWIYSKMESEVRFRKS 567 >gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sapiens] Length = 454 Score = 278 bits (712), Expect = 7e-75 Identities = 154/409 (37%), Positives = 221/409 (54%), Gaps = 21/409 (5%) Query: 168 LIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCV 227 +IG + L++AL + L I F +G C + RCDGV DCK DE CV Sbjct: 53 VIGIIALILALAIGLGIHFDC----SGKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCV 108 Query: 228 RFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSF- 286 R ++L++++ +S W +CS +W Y+ C QLGF S + + F Sbjct: 109 RVGGQNAVLQVFTAAS--WKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQFR 166 Query: 287 -SILRYNSTIQE----SLH-----RSECPSQRYISLQCSHCG-LRAMTGRIVGGALASDS 335 + + + + +LH R C S ++LQC+ CG R + RIVGG ++ S Sbjct: 167 EEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLS 226 Query: 336 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA 395 +WPWQ SL F H+CGG++I W++TAAHC + + + W + G +L P + Sbjct: 227 QWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLY--LPKSWTIQVGLVSLLDNPAPS 284 Query: 396 SIAE-IIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFG 454 + E I+ +S Y + DIALM+L+ PLT + I P CLP + F + CW +G+G Sbjct: 285 HLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWG 344 Query: 455 KTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGP 514 T + SP L V LI K CN VY ++P M+CAG L GG DSCQGDSGGP Sbjct: 345 ATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGP 404 Query: 515 LVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVR 563 LVC++ W L G TS+G GC + NKPGVYT+VT L WI+ +ME +++ Sbjct: 405 LVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLK 453 >gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sapiens] Length = 529 Score = 277 bits (709), Expect = 2e-74 Identities = 162/462 (35%), Positives = 241/462 (52%), Gaps = 32/462 (6%) Query: 115 SPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLL 174 SP Y R + P+ + +S T T ++ T +G L+ Sbjct: 84 SPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLT----------LGTFLV 133 Query: 175 LIALVVSLIILFQFWQ-GHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDK 233 AL L+ F + ++GI + +C + CDGV C DE CVR Sbjct: 134 GAALAAGLLWKFMGSKCSNSGIEC-DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPN 192 Query: 234 SLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNS 293 +L++YS W P+C +WN++Y C+ +G+++ +++ D + S S ++ N+ Sbjct: 193 FILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD-SGSTSFMKLNT 251 Query: 294 T-----IQESLHRSE-CPSQRYISLQCSHCGLR---AMTGRIVGGALASDSKWPWQVSLH 344 + I + L+ S+ C S+ +SL+C CG+ + RIVGG A WPWQVSLH Sbjct: 252 SAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLH 311 Query: 345 FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEG---WKVYAGTSNLHQLPEAAS--IAE 399 H+CGG++I +W++TAAHC EK L W +AG + A + + Sbjct: 312 VQNVHVCGGSIITPEWIVTAAHCV----EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEK 367 Query: 400 IIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRET 459 +I + NY + + DIALM+L KPLT + + P CLP G + CWI+G+G T E Sbjct: 368 VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK 427 Query: 460 DDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQ 519 KTS L +V LI+ ++CN VYD+ +TP M+CAG L+G DSCQGDSGGPLV + Sbjct: 428 G-KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSK 486 Query: 520 NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESE 561 NN W+L G TSWG+GC + +PGVY V WIY +M ++ Sbjct: 487 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRAD 528 >gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sapiens] Length = 492 Score = 277 bits (709), Expect = 2e-74 Identities = 162/462 (35%), Positives = 241/462 (52%), Gaps = 32/462 (6%) Query: 115 SPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLL 174 SP Y R + P+ + +S T T ++ T +G L+ Sbjct: 47 SPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLT----------LGTFLV 96 Query: 175 LIALVVSLIILFQFWQ-GHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDK 233 AL L+ F + ++GI + +C + CDGV C DE CVR Sbjct: 97 GAALAAGLLWKFMGSKCSNSGIEC-DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPN 155 Query: 234 SLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNS 293 +L++YS W P+C +WN++Y C+ +G+++ +++ D + S S ++ N+ Sbjct: 156 FILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD-SGSTSFMKLNT 214 Query: 294 T-----IQESLHRSE-CPSQRYISLQCSHCGLR---AMTGRIVGGALASDSKWPWQVSLH 344 + I + L+ S+ C S+ +SL+C CG+ + RIVGG A WPWQVSLH Sbjct: 215 SAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLH 274 Query: 345 FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEG---WKVYAGTSNLHQLPEAAS--IAE 399 H+CGG++I +W++TAAHC EK L W +AG + A + + Sbjct: 275 VQNVHVCGGSIITPEWIVTAAHCV----EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEK 330 Query: 400 IIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRET 459 +I + NY + + DIALM+L KPLT + + P CLP G + CWI+G+G T E Sbjct: 331 VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK 390 Query: 460 DDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQ 519 KTS L +V LI+ ++CN VYD+ +TP M+CAG L+G DSCQGDSGGPLV + Sbjct: 391 G-KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSK 449 Query: 520 NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESE 561 NN W+L G TSWG+GC + +PGVY V WIY +M ++ Sbjct: 450 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRAD 491 >gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sapiens] Length = 437 Score = 263 bits (671), Expect = 4e-70 Identities = 146/410 (35%), Positives = 215/410 (52%), Gaps = 19/410 (4%) Query: 166 LPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELG 225 +P+I LL +A ++ +++L + + P+ + CDG +DC L DE Sbjct: 34 IPII-IALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQL-CDGELDCPLGEDEEH 91 Query: 226 CV-----------RFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFES--AH 272 CV R D+S L++ ++ W C N+ ++ +E C+Q+G+ S Sbjct: 92 CVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYSSKPTF 151 Query: 273 RTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALA 332 R E+ + I + ++ C S +SL C CG T R+VGG A Sbjct: 152 RAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGGEEA 211 Query: 333 SDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLP 392 S WPWQVS+ + H+CGG+++D WVLTAAHCF + + WKV AG+ L P Sbjct: 212 SVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCF--RKHTDVFNWKVRAGSDKLGSFP 269 Query: 393 EAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITG 452 A III N +D+ DIALM+L PLT S + P CLP + + WI G Sbjct: 270 SLAVAKIIIIEFNPMYPKDN-DIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIG 328 Query: 453 FGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSG 512 +G T++ K S L + V +ID +CN Y +T +MMCAG GG D+CQGDSG Sbjct: 329 WGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSG 388 Query: 513 GPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEV 562 GPL+ Q+++W++ G+ SWG GCG + PGVYTKV+ L WIY+ ++E+ Sbjct: 389 GPLM-YQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL 437 >gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sapiens] Length = 432 Score = 261 bits (667), Expect = 1e-69 Identities = 145/408 (35%), Positives = 214/408 (52%), Gaps = 20/408 (4%) Query: 166 LPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELG 225 +P+I LL +A ++ +++L + + P+ + CDG +DC L DE Sbjct: 34 IPII-IALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQL-CDGELDCPLGEDEEH 91 Query: 226 CV-----------RFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRT 274 CV R D+S L++ ++ W C N+ ++ +E C+Q+G+ R Sbjct: 92 CVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYS---RA 148 Query: 275 TEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASD 334 E+ + I + ++ C S +SL C CG T R+VGG AS Sbjct: 149 VEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGGEEASV 208 Query: 335 SKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEA 394 WPWQVS+ + H+CGG+++D WVLTAAHCF + + WKV AG+ L P Sbjct: 209 DSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCF--RKHTDVFNWKVRAGSDKLGSFPSL 266 Query: 395 ASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFG 454 A III N +D+ DIALM+L PLT S + P CLP + + WI G+G Sbjct: 267 AVAKIIIIEFNPMYPKDN-DIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWG 325 Query: 455 KTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGP 514 T++ K S L + V +ID +CN Y +T +MMCAG GG D+CQGDSGGP Sbjct: 326 FTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGP 385 Query: 515 LVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEV 562 L+ Q+++W++ G+ SWG GCG + PGVYTKV+ L WIY+ ++E+ Sbjct: 386 LM-YQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL 432 >gi|170932492 transmembrane protease, serine 5 [Homo sapiens] Length = 457 Score = 243 bits (621), Expect = 3e-64 Identities = 129/344 (37%), Positives = 181/344 (52%), Gaps = 9/344 (2%) Query: 228 RFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDF----A 283 R + + LL+ +WL +C W+ + + C LG V D + Sbjct: 113 RINSEDFLLEAQVRDQPRWLLVCHEGWSPALGLQICWSLGHLRLTHHKGVNLTDIKLNSS 172 Query: 284 NSFSIL--RYNSTIQESLH-RSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQ 340 F+ L R ++E+ R+ C S + +SL+CS CG R + RIVGG + +WPWQ Sbjct: 173 QEFAQLSPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQ 232 Query: 341 VSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAG-TSNLHQLPEAASIAE 399 S+ G H CGG+++ +WV+TAAHC R L W+V+AG S+ P ++ E Sbjct: 233 ASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALVE 292 Query: 400 III-NSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRE 458 II + Y+ + DYD+AL+RL L S + CLP Q F CW++G+G T Sbjct: 293 RIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHP 352 Query: 459 TDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCE 518 + +S L++ V L + CN VY LTPRM+CAG L G D+CQGDSGGPLVC Sbjct: 353 SHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCP 412 Query: 519 QNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEV 562 + W L GV SWG GC + N PGVY KV E L WI+ + + Sbjct: 413 DGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHDTAQDSL 456 >gi|33695155 hepsin [Homo sapiens] Length = 417 Score = 231 bits (588), Expect = 2e-60 Identities = 134/372 (36%), Positives = 196/372 (52%), Gaps = 29/372 (7%) Query: 214 VVDCKLKSDE--LGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESA 271 +V L+SD+ L V+ + L ++ + W +CSS N + +C+++GF A Sbjct: 39 IVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRA 98 Query: 272 HRTTEVAHRD---------FANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAM 322 +E+ R F L + + E + +CP R+++ C CG R + Sbjct: 99 LTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKL 158 Query: 323 -TGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKV 381 RIVGG S +WPWQVSL + H+CGG+L+ WVLTAAHC F R +VL W+V Sbjct: 159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRV 217 Query: 382 YAGT---SNLHQLPEAASIAEIIINSNY------TDEEDDYDIALMRLSKPLTLSAHIHP 432 +AG ++ H L + ++ + Y EE+ DIAL+ LS PL L+ +I P Sbjct: 218 FAGAVAQASPHGL--QLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 275 Query: 433 ACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTP 492 CLP GQ + C +TG+G T+ + L+E +V +I CN Y + + P Sbjct: 276 VCLPAAGQALVDGKICTVTGWGNTQYYGQQAG-VLQEARVPIISNDVCNGADFYGNQIKP 334 Query: 493 RMMCAGDLRGGRDSCQGDSGGPLVCE----QNNRWYLAGVTSWGTGCGQRNKPGVYTKVT 548 +M CAG GG D+CQGDSGGP VCE + RW L G+ SWGTGC KPGVYTKV+ Sbjct: 335 KMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVS 394 Query: 549 EVLPWIYSKMES 560 + WI+ +++ Sbjct: 395 DFREWIFQAIKT 406 >gi|4504481 hepsin [Homo sapiens] Length = 417 Score = 231 bits (588), Expect = 2e-60 Identities = 134/372 (36%), Positives = 196/372 (52%), Gaps = 29/372 (7%) Query: 214 VVDCKLKSDE--LGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESA 271 +V L+SD+ L V+ + L ++ + W +CSS N + +C+++GF A Sbjct: 39 IVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRA 98 Query: 272 HRTTEVAHRD---------FANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAM 322 +E+ R F L + + E + +CP R+++ C CG R + Sbjct: 99 LTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKL 158 Query: 323 -TGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKV 381 RIVGG S +WPWQVSL + H+CGG+L+ WVLTAAHC F R +VL W+V Sbjct: 159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRV 217 Query: 382 YAGT---SNLHQLPEAASIAEIIINSNY------TDEEDDYDIALMRLSKPLTLSAHIHP 432 +AG ++ H L + ++ + Y EE+ DIAL+ LS PL L+ +I P Sbjct: 218 FAGAVAQASPHGL--QLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 275 Query: 433 ACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTP 492 CLP GQ + C +TG+G T+ + L+E +V +I CN Y + + P Sbjct: 276 VCLPAAGQALVDGKICTVTGWGNTQYYGQQAG-VLQEARVPIISNDVCNGADFYGNQIKP 334 Query: 493 RMMCAGDLRGGRDSCQGDSGGPLVCE----QNNRWYLAGVTSWGTGCGQRNKPGVYTKVT 548 +M CAG GG D+CQGDSGGP VCE + RW L G+ SWGTGC KPGVYTKV+ Sbjct: 335 KMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVS 394 Query: 549 EVLPWIYSKMES 560 + WI+ +++ Sbjct: 395 DFREWIFQAIKT 406 >gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] Length = 638 Score = 217 bits (553), Expect = 2e-56 Identities = 113/253 (44%), Positives = 157/253 (62%), Gaps = 13/253 (5%) Query: 315 SHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTT---HICGGTLIDAQWVLTAAHCFFVT 371 S C + T RIVGG +S +WPWQVSL T H+CGG+LI QWVLTAAHCF Sbjct: 381 SVCTTKTST-RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF--D 437 Query: 372 REKVLEGWKVYAGTSNLHQLPEA---ASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSA 428 + + W++Y+G NL + + + I EIII+ NY E ++DIAL++L PL + Sbjct: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE 497 Query: 429 HIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDS 488 P CLP G T ++ CW+TG+G ++E + + L++V + L+ ++C Y Sbjct: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQN-ILQKVNIPLVTNEECQKR--YQD 554 Query: 489 Y-LTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKV 547 Y +T RM+CAG GG+D+C+GDSGGPLVC+ N W L G+TSWG GC +R +PGVYTKV Sbjct: 555 YKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKV 614 Query: 548 TEVLPWIYSKMES 560 E + WI K +S Sbjct: 615 AEYMDWILEKTQS 627 >gi|223942069 enterokinase precursor [Homo sapiens] Length = 1019 Score = 213 bits (541), Expect = 5e-55 Identities = 126/370 (34%), Positives = 183/370 (49%), Gaps = 39/370 (10%) Query: 211 CDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQ-----------WLPICSSNWNDSYS 259 CDG + C+ SDE CVRF ++G+++ W C+ NW S Sbjct: 662 CDGHLHCEDGSDEADCVRF---------FNGTTNNNGLVRFRIQSIWHTACAENWTTQIS 712 Query: 260 EKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESL---HRSECPSQRYISLQCSH 316 CQ LG S + + + D ++ N+ L +C I LQC+H Sbjct: 713 NDVCQLLGLGSGNSSKPIFSTDGG---PFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNH 769 Query: 317 --CGLRA----MTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFV 370 CG + +T +IVGG+ A + WPW V L++G +CG +L+ + W+++AAHC + Sbjct: 770 KSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVY- 828 Query: 371 TREKVLEGWKVYAGTSNLHQLPEAASIA----EIIINSNYTDEEDDYDIALMRLSKPLTL 426 R W G L ++ EI+IN +Y D DIA+M L + Sbjct: 829 GRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNY 888 Query: 427 SAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVY 486 + +I P CLP Q F C I G+G T T+ L+E V L+ ++C + Sbjct: 889 TDYIQPICLPEENQVFPPGRNCSIAGWG-TVVYQGTTANILQEADVPLLSNERCQQQMP- 946 Query: 487 DSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTK 546 + +T M+CAG GG DSCQGDSGGPL+C++NNRW+LAGVTS+G C N+PGVY + Sbjct: 947 EYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYAR 1006 Query: 547 VTEVLPWIYS 556 V+ WI S Sbjct: 1007 VSRFTEWIQS 1016 >gi|23957702 transmembrane protease, serine 6 [Homo sapiens] Length = 811 Score = 211 bits (536), Expect = 2e-54 Identities = 107/242 (44%), Positives = 149/242 (61%), Gaps = 7/242 (2%) Query: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376 CGL+ + RIVGGA++S+ +WPWQ SL HICGG LI +WV+TAAHCF Sbjct: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627 Query: 377 EGWKVYAGT--SNLHQLPEAA-SIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433 W V+ G N E + ++ ++++ + ++ DYD+AL++L P+ SA + P Sbjct: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPV 687 Query: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPR 493 CLP F CWITG+G RE S L++V V LI C++ VY +TPR Sbjct: 688 CLPARSHFFEPGLHCWITGWGALRE-GGPISNALQKVDVQLIPQDLCSE--VYRYQVTPR 744 Query: 494 MMCAGDLRGGRDSCQGDSGGPLVCEQ-NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLP 552 M+CAG +G +D+CQGDSGGPLVC+ + RW+LAG+ SWG GCG+ N GVYT++T V+ Sbjct: 745 MLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVIS 804 Query: 553 WI 554 WI Sbjct: 805 WI 806 >gi|222831592 transmembrane protease, serine 7 [Homo sapiens] Length = 717 Score = 208 bits (529), Expect = 1e-53 Identities = 127/364 (34%), Positives = 182/364 (50%), Gaps = 25/364 (6%) Query: 204 CPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWND---SYSE 260 C A RCDGV DC +SDEL CV + S Q P+ + D E Sbjct: 370 CVPQAQRCDGVNDCFDESDELFCV-----SPQPACNTSSFRQHGPLICDGFRDCENGRDE 424 Query: 261 KTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLR 320 + C Q +RT + N + N+ ++ +CP C+ Sbjct: 425 QNCTQ-SIPCNNRTFKC-----GNDICFRKQNAKCDGTV---DCPDGS-DEEGCTCSRSS 474 Query: 321 AMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWK 380 + RI+GG + WPWQVSLHF + CG ++I +W+L+AAHCF R W Sbjct: 475 SALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWT 534 Query: 381 VYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLS--KPLTLSAHIHPACLPMH 438 + G + + I+++ Y + DYDIAL++LS P TL I P C+P Sbjct: 535 AHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPT 594 Query: 439 GQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAG 498 GQ E CW+TG+G+ E D+K S L++ +V LID C + +T RM+CAG Sbjct: 595 GQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLC---VSTYGIITSRMLCAG 651 Query: 499 DLRGGRDSCQGDSGGPLVC--EQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYS 556 + G RD+C+GDSGGPL C + + +W L G+ SWG G G+ N PGVYT+V+ +PWI+ Sbjct: 652 IMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWIHK 711 Query: 557 KMES 560 + S Sbjct: 712 YVPS 715 >gi|58218970 protease, serine, 36 [Homo sapiens] Length = 855 Score = 204 bits (520), Expect = 1e-52 Identities = 109/252 (43%), Positives = 144/252 (57%), Gaps = 17/252 (6%) Query: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFV--TREK 374 CG + RIVGG+ A WPWQVSLH G HICGG+LI WVL+AAHCF T E Sbjct: 38 CGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEP 97 Query: 375 VLEGWKVYAGTSNLHQLPEAA---SIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIH 431 E W V G + + A ++A I++ +NY+ E D+AL+RL+ P +L + Sbjct: 98 AAE-WSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVW 156 Query: 432 PACLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDS-- 488 P CLP F CW TG+G +E D P+ L+EV++ L+ C +Y Sbjct: 157 PVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQ--CLYSQPG 214 Query: 489 ------YLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPG 542 + P M+CAG G RD+CQGDSGGPLVCE+ RW+ AG+TS+G GCG+RN+PG Sbjct: 215 PFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPG 274 Query: 543 VYTKVTEVLPWI 554 V+T V WI Sbjct: 275 VFTAVATYEAWI 286 Score = 75.1 bits (183), Expect = 2e-13 Identities = 55/219 (25%), Positives = 89/219 (40%), Gaps = 19/219 (8%) Query: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376 CGLR + G L WPW +H +C G L+ WVL A HC + Sbjct: 588 CGLRLEAAPV--GVL-----WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTV 640 Query: 377 EGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEED-DYDIALMRLSKPLTLSAHIHPACL 435 +VY G + LP+ ++ ++I+ +AL+ LS + S P CL Sbjct: 641 PYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICL 700 Query: 436 PMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMM 495 H +CW+ G+ +E D+ V+++ + C+ +Y L P + Sbjct: 701 --HPAGIPPGASCWVLGW---KEPQDRVPV---AAAVSILTQRICD--CLYQGILPPGTL 750 Query: 496 CAGDLRGGRDSCQGDSGGPLVCEQ-NNRWYLAGVTSWGT 533 C G + C+ S PL+C+ W L G+ G+ Sbjct: 751 CVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGS 789 Score = 71.2 bits (173), Expect = 2e-12 Identities = 56/230 (24%), Positives = 93/230 (40%), Gaps = 25/230 (10%) Query: 337 WPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTRE-----KVLEGWKVYAGTSNLHQL 391 WPW+ + + C G L+ WVL A CF + L+ W+V L Sbjct: 334 WPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVL-----LPSR 388 Query: 392 PEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWIT 451 P A +A ++ + N ++ D+AL++L P+ LSA P CLP F C + Sbjct: 389 PRAERVARLVQHEN-ASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLA 447 Query: 452 GFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLT------PRMMC-AGDLRGGR 504 +G+ + ++ L+ C+ P +C A + Sbjct: 448 RWGRGEPALGPGA----LLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEV 503 Query: 505 DSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554 SC DS L+C++ W+LAG+ + +GC +P + + PWI Sbjct: 504 GSCWNDSRWSLLCQEEGTWFLAGIRDFPSGC---LRPRAFFPLQTHGPWI 550 >gi|4503627 coagulation factor XI precursor [Homo sapiens] Length = 625 Score = 201 bits (510), Expect = 2e-51 Identities = 103/244 (42%), Positives = 148/244 (60%), Gaps = 14/244 (5%) Query: 325 RIVGGALASDSKWPWQVSLHFGTT---HICGGTLIDAQWVLTAAHCFF-VTREKVLEGWK 380 RIVGG + +WPWQV+LH + H+CGG++I QW+LTAAHCF+ V K+L + Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKIL---R 443 Query: 381 VYAGTSNLHQLPEAAS---IAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPM 437 VY+G N ++ E S + EIII+ Y E YDIAL++L + + P CLP Sbjct: 444 VYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPS 503 Query: 438 HGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSY-LTPRMMC 496 G + CW+TG+G R+ DK L++ ++ L+ ++C Y + +T +M+C Sbjct: 504 KGDRNVIYTDCWVTGWGY-RKLRDKIQNTLQKAKIPLVTNEECQKR--YRGHKITHKMIC 560 Query: 497 AGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYS 556 AG GG+D+C+GDSGGPL C+ N W+L G+TSWG GC QR +PGVYT V E + WI Sbjct: 561 AGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILE 620 Query: 557 KMES 560 K ++ Sbjct: 621 KTQA 624 >gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] Length = 321 Score = 200 bits (508), Expect = 3e-51 Identities = 109/253 (43%), Positives = 148/253 (58%), Gaps = 9/253 (3%) Query: 306 SQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAA 365 S R + C + GRIVGG A WPWQ SL H+CGG+L+ QWVLTAA Sbjct: 18 SLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAA 77 Query: 366 HCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDY-DIALMRLSKPL 424 HCF + ++V+ G + P +++ +II++S+ + + DIAL+ LS P+ Sbjct: 78 HCFSGSLNS--SDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPV 135 Query: 425 TLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCN-D 482 TLS+ I P CLP F CW+TG+G TRE + P+ LREV+V+++D + C D Sbjct: 136 TLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRD 195 Query: 483 YL-VYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKP 541 Y S L P M+CA RG D+CQ DSGGPLVC+ N W AG+ SWG GCG+ N+P Sbjct: 196 YPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRP 252 Query: 542 GVYTKVTEVLPWI 554 GVYT+V + WI Sbjct: 253 GVYTRVPAYVNWI 265 >gi|40254871 transmembrane protease, serine 11E [Homo sapiens] Length = 423 Score = 199 bits (507), Expect = 4e-51 Identities = 109/275 (39%), Positives = 150/275 (54%), Gaps = 13/275 (4%) Query: 284 NSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSL 343 +S I + N T +S C ++R +L + RIVGG + +WPWQ SL Sbjct: 158 HSVKIKKINKTETDSYLNHCCGTRRSKTL--------GQSLRIVGGTEVEEGEWPWQASL 209 Query: 344 HFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIIN 403 + +H CG TLI+A W+++AAHCF T K W G + + + II++ Sbjct: 210 QWDGSHRCGATLINATWLVSAAHCF--TTYKNPARWTASFGVT-IKPSKMKRGLRRIIVH 266 Query: 404 SNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKT 463 Y DYDI+L LS P+ + +H CLP F + ++TGFG + D + Sbjct: 267 EKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKN-DGYS 325 Query: 464 SPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLV-CEQNNR 522 LR+ QV LID CN+ Y+ +TPRM+CAG L G D+CQGDSGGPLV + + Sbjct: 326 QNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDI 385 Query: 523 WYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSK 557 WYLAG+ SWG C + NKPGVYT+VT + WI SK Sbjct: 386 WYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK 420 >gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] Length = 423 Score = 199 bits (506), Expect = 6e-51 Identities = 109/274 (39%), Positives = 149/274 (54%), Gaps = 13/274 (4%) Query: 285 SFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLH 344 S I + N T +S C ++R +L + RIVGG + +WPWQ SL Sbjct: 159 SVKIKKINKTETDSYLNHCCGTRRSKTL--------GQSLRIVGGTEVEEGEWPWQASLQ 210 Query: 345 FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINS 404 + +H CG TLI+A W+++AAHCF T K W G + + + II++ Sbjct: 211 WDGSHRCGATLINATWLVSAAHCF--TTYKNPARWTASFGVT-IKPSKMKRGLRRIIVHE 267 Query: 405 NYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTS 464 Y DYDI+L LS P+ + +H CLP F + ++TGFG + D + Sbjct: 268 KYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKN-DGYSQ 326 Query: 465 PFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLV-CEQNNRW 523 LR+ QV LID CN+ Y+ +TPRM+CAG L G D+CQGDSGGPLV + + W Sbjct: 327 NHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIW 386 Query: 524 YLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSK 557 YLAG+ SWG C + NKPGVYT+VT + WI SK Sbjct: 387 YLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK 420 >gi|21614531 testisin isoform 2 [Homo sapiens] Length = 312 Score = 197 bits (501), Expect = 2e-50 Identities = 106/255 (41%), Positives = 142/255 (55%), Gaps = 17/255 (6%) Query: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376 CG R +T RIVGG A +WPWQ SL +H+CG +L+ +W LTAAHCF T Sbjct: 33 CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCF-ETDLSDP 91 Query: 377 EGWKVYAGTSNLHQLPEAAS---------IAEIIINSNYTDEEDDYDIALMRLSKPLTLS 427 GW V G L +P S ++ I ++ Y YDIAL++LS P+T + Sbjct: 92 SGWMVQFG--QLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSP-YDIALVKLSAPVTYT 148 Query: 428 AHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVY 486 HI P CL F CW+TG+G +E + SP L+EVQV +I+ CN + Sbjct: 149 KHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK 208 Query: 487 DSY---LTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGV 543 S+ + M+CAG+ +GG+D+C GDSGGPL C +N WY GV SWG GCG+ N+PGV Sbjct: 209 YSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGV 268 Query: 544 YTKVTEVLPWIYSKM 558 YT ++ WI M Sbjct: 269 YTNISHHFEWIQKLM 283 >gi|4506153 prostasin preproprotein [Homo sapiens] Length = 343 Score = 196 bits (499), Expect = 4e-50 Identities = 103/252 (40%), Positives = 145/252 (57%), Gaps = 13/252 (5%) Query: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376 CG+ A RI GG+ A +WPWQVS+ + H+CGG+L+ QWVL+AAHCF K Sbjct: 37 CGV-APQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHK-- 93 Query: 377 EGWKVYAGTSNLHQLPEAASIA---EIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433 E ++V G L E A ++ +II + +Y E DIAL++LS+P+T S +I P Sbjct: 94 EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPI 153 Query: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDS---- 488 CLP +F C +TG+G + +P L++++V LI + CN D+ Sbjct: 154 CLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEE 213 Query: 489 --YLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTK 546 ++ M+CAG + GG+D+CQGDSGGPL C WYL G+ SWG CG RN+PGVYT Sbjct: 214 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTL 273 Query: 547 VTEVLPWIYSKM 558 + WI SK+ Sbjct: 274 ASSYASWIQSKV 285 >gi|5803197 testisin isoform 1 [Homo sapiens] Length = 314 Score = 196 bits (499), Expect = 4e-50 Identities = 105/256 (41%), Positives = 142/256 (55%), Gaps = 17/256 (6%) Query: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTRE-KV 375 CG R +T RIVGG A +WPWQ SL +H+CG +L+ +W LTAAHCF + Sbjct: 33 CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92 Query: 376 LEGWKVYAGTSNLHQLPEAAS---------IAEIIINSNYTDEEDDYDIALMRLSKPLTL 426 GW V G L +P S ++ I ++ Y YDIAL++LS P+T Sbjct: 93 PSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSP-YDIALVKLSAPVTY 149 Query: 427 SAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLV 485 + HI P CL F CW+TG+G +E + SP L+EVQV +I+ CN + Sbjct: 150 TKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFL 209 Query: 486 YDSY---LTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPG 542 S+ + M+CAG+ +GG+D+C GDSGGPL C +N WY GV SWG GCG+ N+PG Sbjct: 210 KYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPG 269 Query: 543 VYTKVTEVLPWIYSKM 558 VYT ++ WI M Sbjct: 270 VYTNISHHFEWIQKLM 285 >gi|29244926 corin [Homo sapiens] Length = 1042 Score = 196 bits (497), Expect = 6e-50 Identities = 128/374 (34%), Positives = 188/374 (50%), Gaps = 31/374 (8%) Query: 203 SCPKHAVRCDGVVDCKLKSDELGCVRFDWD---KSLLKIYSGSSHQWLPICSSNWNDSYS 259 +C + CDG DC SDE CV + S L ++ ++ +C+ W + S Sbjct: 666 ACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHH--VCADGWQEILS 723 Query: 260 EKTCQQLGFESAHRTTEVAHRDFANSFSILRYN------STIQESLHRSE-CPSQRYISL 312 + C+Q+G T + ++ + L N +T+ E L + C S+ ISL Sbjct: 724 QLACKQMGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISL 783 Query: 313 QCSH--CGLRA---MTGRIVGGALASDSKWPWQVSLHFGTT-HICGGTLIDAQWVLTAAH 366 C+ CG R M RI+GG + +WPWQ SL + HICG LI +WVLT AH Sbjct: 784 LCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAH 843 Query: 367 CFFVTREKVLEGWKVYAGTSNLHQ---LPEAASIAEIIINSNYTDEEDDYDIALMRLSKP 423 CF + WKV G +NL + + II++ Y+ DYDI+++ LS+ Sbjct: 844 CFEGRENAAV--WKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSED 901 Query: 424 LTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCND 482 ++ + ++ P CLP Q + C+ITG+G PF L+E +V +I + C Sbjct: 902 ISETGYVRPVCLPNPEQWLEPDTYCYITGWGHM----GNKMPFKLQEGEVRIISLEHCQS 957 Query: 483 YLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQ-NNRWYLAGVTSWGTGCGQR-NK 540 Y + +T RM+CAG G DSC GDSGGPLVCE+ RW L G+TSWG+ C + Sbjct: 958 YFDMKT-ITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLG 1016 Query: 541 PGVYTKVTEVLPWI 554 PGVY+ V+ + WI Sbjct: 1017 PGVYSNVSYFVEWI 1030 >gi|33667063 transmembrane protease, serine 9 [Homo sapiens] Length = 1059 Score = 195 bits (496), Expect = 8e-50 Identities = 100/241 (41%), Positives = 148/241 (61%), Gaps = 9/241 (3%) Query: 325 RIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAG 384 R+VGG A+ + PWQVSL G+ H CG T++ +W+L+AAHCF T+ +E + + G Sbjct: 503 RVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTK---VEQVRAHLG 559 Query: 385 TSNLHQL---PEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQT 441 T++L L P + ++++ Y D+D+A++ L+ PL + +I P CLP+ Q Sbjct: 560 TASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQK 619 Query: 442 FSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLR 501 F + C I+G+G T+E + L++ V +ID K C+ ++Y+ LT RM+CAG L Sbjct: 620 FPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCS--VLYNFSLTDRMICAGFLE 677 Query: 502 GGRDSCQGDSGGPLVCEQ-NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560 G DSCQGDSGGPL CE+ +YLAG+ SWG GC Q KPGVYT++T + WI M S Sbjct: 678 GKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSS 737 Query: 561 E 561 + Sbjct: 738 Q 738 Score = 187 bits (476), Expect = 2e-47 Identities = 99/245 (40%), Positives = 141/245 (57%), Gaps = 11/245 (4%) Query: 317 CGLRA---MTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTRE 373 CGL+ M GRIVGG AS ++PWQ SL H CG +I+A+W+++AAHCF ++ Sbjct: 191 CGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQD 250 Query: 374 KVLEGWKVYAGTSNLHQLPEA---ASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHI 430 W Y G + L + A + +I+ + Y + D+D+A++ L+ PL HI Sbjct: 251 PT--KWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHI 308 Query: 431 HPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYL 490 P CLP F ++ C I+G+G +E L++ V L+D C +Y L Sbjct: 309 QPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCAS--LYGHSL 366 Query: 491 TPRMMCAGDLRGGRDSCQGDSGGPLVCEQ-NNRWYLAGVTSWGTGCGQRNKPGVYTKVTE 549 T RM+CAG L G DSCQGDSGGPLVCE+ + R++LAG+ SWG GC + +PGVY +VT Sbjct: 367 TDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTR 426 Query: 550 VLPWI 554 + WI Sbjct: 427 LRDWI 431 Score = 167 bits (424), Expect = 2e-41 Identities = 100/246 (40%), Positives = 132/246 (53%), Gaps = 9/246 (3%) Query: 313 QCSHCGLR-AMTGRIVGGALASDSKWPWQVSLHFGTT-HICGGTLIDAQWVLTAAHCFFV 370 Q CGL A RIVGG+ A +WPWQVSL H CG L+ +W+L+AAHCF V Sbjct: 813 QLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDV 872 Query: 371 TREKVLEGWKVYAGTSNLHQLP-EAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAH 429 + + W + GT L + +A I + Y DYD+AL+ L+ P+ S Sbjct: 873 YGDP--KQWAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRL 930 Query: 430 IHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSY 489 + P CLP C ITG+G RE L++ V L+ + C + Y Sbjct: 931 VRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQ-LQKAAVRLLSEQTCRRF--YPVQ 987 Query: 490 LTPRMMCAGDLRGGRDSCQGDSGGPLVC-EQNNRWYLAGVTSWGTGCGQRNKPGVYTKVT 548 ++ RM+CAG +GG DSC GD+GGPL C E + RW L GVTSWG GCG+ + PGVYT+V Sbjct: 988 ISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVA 1047 Query: 549 EVLPWI 554 V WI Sbjct: 1048 AVRGWI 1053 Score = 30.8 bits (68), Expect = 3.5 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 2/76 (2%) Query: 39 ASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSR 98 + P SP T A+ + + AG A+P R +P AS PA ++ L+++S Sbjct: 737 SQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANST--LSAVST 794 Query: 99 SSSGRSSSARSASVTT 114 ++ G++ + TT Sbjct: 795 TARGQTPFPDAPEATT 810 >gi|11415040 matriptase [Homo sapiens] Length = 855 Score = 187 bits (476), Expect = 2e-47 Identities = 123/357 (34%), Positives = 172/357 (48%), Gaps = 28/357 (7%) Query: 211 CDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSS--NWNDSYSEKTCQQLGF 268 CD V DC SDE GC + +G C+ + D E +C ++ Sbjct: 508 CDSVNDCGDNSDEQGC---SCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNV 564 Query: 269 ESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMT--GRI 326 + + T N + + N S+ ++ C CGLR+ T R+ Sbjct: 565 VTCTKHTYRC----LNGLCLSKGNPECDGKEDCSDGSDEK----DCD-CGLRSFTRQARV 615 Query: 327 VGGALASDSKWPWQVSLH-FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEG---WKVY 382 VGG A + +WPWQVSLH G HICG +LI W+++AAHC+ R W + Sbjct: 616 VGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAF 675 Query: 383 AGTSNLHQLP----EAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMH 438 G + Q + + II + + D DYDIAL+ L KP S+ + P CLP Sbjct: 676 LGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDA 735 Query: 439 GQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAG 498 F + W+TG+G T + + L++ ++ +I+ C + L +TPRMMC G Sbjct: 736 SHVFPAGKAIWVTGWGHT-QYGGTGALILQKGEIRVINQTTCENLL--PQQITPRMMCVG 792 Query: 499 DLRGGRDSCQGDSGGPL-VCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554 L GG DSCQGDSGGPL E + R + AGV SWG GC QRNKPGVYT++ WI Sbjct: 793 FLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWI 849 >gi|4506143 neurotrypsin precursor [Homo sapiens] Length = 875 Score = 187 bits (476), Expect = 2e-47 Identities = 122/363 (33%), Positives = 177/363 (48%), Gaps = 62/363 (17%) Query: 245 QWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNST---------- 294 QW IC W D + C+QLG++ R +A+ F + ++ Sbjct: 520 QWGTICDDGWTDKDAAVICRQLGYKGPARARTMAY--FGEGKGPIHVDNVKCTGNERSLA 577 Query: 295 --IQESLHRSECPSQRYISLQCSH-----------------CGLRAM---TGRIVGGALA 332 I++ + R C + C + CGLR + RI+GG + Sbjct: 578 DCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNS 637 Query: 333 SDSKWPWQVSLHFGTTH-----ICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYA-GTS 386 WPWQVSL ++H +CG TL+ + WVLTAAHCF ++ + YA Sbjct: 638 LRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCF----KRYGNSTRSYAVRVG 693 Query: 387 NLHQL-----PEAASIAEIIINSNYTDEEDDYDIALMRLSKP----LTLSAHIHPACLPM 437 + H L E + +I+I+ Y + DYDIAL+RL P S+H+ PACLP+ Sbjct: 694 DYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPACLPL 753 Query: 438 -HGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMC 496 + C+ITG+G T +T L++ + L+ + C + Y T RM+C Sbjct: 754 WRERPQKTASNCYITGWGDTGRAYSRT---LQQAAIPLLPKRFCEER--YKGRFTGRMLC 808 Query: 497 AGDLRGGR--DSCQGDSGGPLVCEQ-NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPW 553 AG+L + DSCQGDSGGPL+CE+ W + GVTSWG GCG ++ PGVYTKV+ +PW Sbjct: 809 AGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPW 868 Query: 554 IYS 556 I S Sbjct: 869 IKS 871 Score = 34.7 bits (78), Expect = 0.24 Identities = 17/72 (23%), Positives = 28/72 (38%) Query: 245 QWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSEC 304 QW +C W+D+ +E C+QLG + A+ + +L L +C Sbjct: 300 QWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQC 359 Query: 305 PSQRYISLQCSH 316 P + C H Sbjct: 360 PKSSWGEHNCGH 371 Score = 30.0 bits (66), Expect = 5.9 Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 3/54 (5%) Query: 213 GVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQL 266 G DC+ S L + +++ ++ ++Y+ S W +CSS+W+DS + C QL Sbjct: 161 GYCDCRHGSVRLRGGKNEFEGTV-EVYA--SGVWGTVCSSHWDDSDASVICHQL 211 >gi|4505881 plasminogen [Homo sapiens] Length = 810 Score = 185 bits (470), Expect = 8e-47 Identities = 103/239 (43%), Positives = 137/239 (57%), Gaps = 10/239 (4%) Query: 324 GRIVGGALASDSKWPWQVSLH--FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKV 381 GR+VGG +A WPWQVSL FG H CGGTLI +WVLTAAHC + + +KV Sbjct: 579 GRVVGGCVAHPHSWPWQVSLRTRFGM-HFCGGTLISPEWVLTAAHC--LEKSPRPSSYKV 635 Query: 382 YAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQT 441 G HQ + I S E DIAL++LS P ++ + PACLP Sbjct: 636 ILGA---HQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYV 692 Query: 442 FSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLR 501 + C+ITG+G+T+ T + L+E Q+ +I+ K CN Y + + +CAG L Sbjct: 693 VADRTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLA 750 Query: 502 GGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560 GG DSCQGDSGGPLVC + +++ L GVTSWG GC + NKPGVY +V+ + WI M + Sbjct: 751 GGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRN 809 >gi|4758508 transmembrane protease, serine 11D [Homo sapiens] Length = 418 Score = 185 bits (470), Expect = 8e-47 Identities = 99/232 (42%), Positives = 131/232 (56%), Gaps = 7/232 (3%) Query: 325 RIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAG 384 RI+GG A + WPWQVSL H CGG+LI+ W+LTAAHCF W +G Sbjct: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNP--RDWIATSG 243 Query: 385 TSNLHQLPE-AASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFS 443 S P+ + I+I++NY + DIAL+RL +T + IH CLP Q Sbjct: 244 IST--TFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIP 301 Query: 444 LNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGG 503 T ++TG+G +E T P LR+ QV +I CN Y+ + M+CAG +GG Sbjct: 302 PGSTAYVTGWG-AQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGG 360 Query: 504 RDSCQGDSGGPLVCEQNNR-WYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554 D+CQGDSGGPLV E + R W++ G+ SWG CG +KPGVYT+VT L WI Sbjct: 361 VDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412 >gi|68508970 tryptase beta 2 precursor [Homo sapiens] Length = 275 Score = 184 bits (468), Expect = 1e-46 Identities = 100/241 (41%), Positives = 137/241 (56%), Gaps = 14/241 (5%) Query: 326 IVGGALASDSKWPWQVSLHFGTT---HICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVY 382 IVGG A SKWPWQVSL H CGG+LI QWVLTAAHC K L +V Sbjct: 31 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPD-VKDLAALRVQ 89 Query: 383 AGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTF 442 +L+ + ++ II++ + + DIAL+ L +P+ +S+H+H LP +TF Sbjct: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 Query: 443 SLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDSY-------LTPRM 494 CW+TG+G + PF L++V+V +++ C+ +Y + M Sbjct: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 Query: 495 MCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554 +CAG+ R RDSCQGDSGGPLVC+ N W AGV SWG GC Q N+PG+YT+VT L WI Sbjct: 210 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 Query: 555 Y 555 + Sbjct: 268 H 268 >gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] Length = 275 Score = 184 bits (467), Expect = 2e-46 Identities = 100/241 (41%), Positives = 137/241 (56%), Gaps = 14/241 (5%) Query: 326 IVGGALASDSKWPWQVSLHFGTT---HICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVY 382 IVGG A SKWPWQVSL H CGG+LI QWVLTAAHC K L +V Sbjct: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPD-VKDLAALRVQ 89 Query: 383 AGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTF 442 +L+ + ++ II++ + + DIAL+ L +P+ +S+H+H LP +TF Sbjct: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149 Query: 443 SLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDSY-------LTPRM 494 CW+TG+G + PF L++V+V +++ C+ +Y + M Sbjct: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209 Query: 495 MCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554 +CAG+ R RDSCQGDSGGPLVC+ N W AGV SWG GC Q N+PG+YT+VT L WI Sbjct: 210 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267 Query: 555 Y 555 + Sbjct: 268 H 268 >gi|13994276 marapsin [Homo sapiens] Length = 290 Score = 183 bits (465), Expect = 3e-46 Identities = 101/250 (40%), Positives = 135/250 (54%), Gaps = 13/250 (5%) Query: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376 CG M R+VGG + +WPWQVS+ +H CGG+LI QWVLTAAHCF T E L Sbjct: 26 CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSL 85 Query: 377 EGWKVYAGTSNLHQL-PEA--ASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433 ++V G L Q P A A + ++ N Y D+AL+ L P+ + +I P Sbjct: 86 --YQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPV 143 Query: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSP-FLREVQVNLIDFKKCN-------DYLV 485 CLP F CW+TG+G E D P L+++ V +ID KCN ++ Sbjct: 144 CLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGY 203 Query: 486 YDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYT 545 + M+CAG G +D+C+GDSGGPLVC W AGV SWG GC ++N+PGVY Sbjct: 204 QPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYI 263 Query: 546 KVTEVLPWIY 555 +VT WI+ Sbjct: 264 RVTAHHNWIH 273 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.130 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,536,904 Number of Sequences: 37866 Number of extensions: 1494171 Number of successful extensions: 36856 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 788 Number of HSP's successfully gapped in prelim test: 1680 Number of HSP's that attempted gapping in prelim test: 13895 Number of HSP's gapped (non-prelim): 13294 length of query: 567 length of database: 18,247,518 effective HSP length: 108 effective length of query: 459 effective length of database: 14,157,990 effective search space: 6498517410 effective search space used: 6498517410 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.