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Search of human proteins with 116235472
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116235472 SH3-domain GRB2-like (endophilin) interacting
protein 1 [Homo sapiens]
(828 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 1695 0.0
gi|226371725 FCH domain only 2 isoform b [Homo sapiens] 480 e-135
gi|226371723 FCH domain only 2 isoform a [Homo sapiens] 480 e-135
gi|239049540 FCH domain only 1 isoform c [Homo sapiens] 312 7e-85
gi|239049457 FCH domain only 1 isoform b [Homo sapiens] 312 7e-85
gi|29789054 FCH domain only 1 isoform b [Homo sapiens] 312 7e-85
gi|239049440 FCH domain only 1 isoform a [Homo sapiens] 306 5e-83
gi|116284392 mucin 2 precursor [Homo sapiens] 85 3e-16
gi|150170670 piccolo isoform 2 [Homo sapiens] 84 4e-16
gi|150378539 piccolo isoform 1 [Homo sapiens] 84 4e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 84 5e-16
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 82 2e-15
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 82 2e-15
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 81 5e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 81 5e-15
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 80 6e-15
gi|163965366 nascent polypeptide-associated complex alpha subuni... 79 1e-14
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 78 4e-14
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 78 4e-14
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 77 5e-14
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 77 5e-14
gi|11386183 WAS protein family, member 2 [Homo sapiens] 77 7e-14
gi|160707881 formin 2 [Homo sapiens] 76 1e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 2e-13
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 74 4e-13
gi|150417989 cyclin K isoform 1 [Homo sapiens] 72 2e-12
gi|7706501 WW domain binding protein 11 [Homo sapiens] 72 2e-12
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 72 2e-12
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 71 5e-12
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 71 5e-12
>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
1 [Homo sapiens]
Length = 828
Score = 1695 bits (4389), Expect = 0.0
Identities = 828/828 (100%), Positives = 828/828 (100%)
Query: 1 MMEGLKKRTRKAFGIRKKEKDTDSTGSPDRDGIQPSPHEPPYNSKAECAREGGKKVSKKS 60
MMEGLKKRTRKAFGIRKKEKDTDSTGSPDRDGIQPSPHEPPYNSKAECAREGGKKVSKKS
Sbjct: 1 MMEGLKKRTRKAFGIRKKEKDTDSTGSPDRDGIQPSPHEPPYNSKAECAREGGKKVSKKS 60
Query: 61 NGAPNGFYAEIDWERYNSPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIK 120
NGAPNGFYAEIDWERYNSPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIK
Sbjct: 61 NGAPNGFYAEIDWERYNSPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIK 120
Query: 121 IKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRST 180
IKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRST
Sbjct: 121 IKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRST 180
Query: 181 PTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLT 240
PTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLT
Sbjct: 181 PTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLT 240
Query: 241 RPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLS 300
RPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLS
Sbjct: 241 RPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLS 300
Query: 301 PKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGP 360
PKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGP
Sbjct: 301 PKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGP 360
Query: 361 PGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYR 420
PGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYR
Sbjct: 361 PGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYR 420
Query: 421 TVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGD 480
TVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGD
Sbjct: 421 TVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGD 480
Query: 481 VSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPSLVWFDRGKFYL 540
VSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPSLVWFDRGKFYL
Sbjct: 481 VSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPSLVWFDRGKFYL 540
Query: 541 TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGADPSKCIVKITGEMVLSFPAGITR 600
TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGADPSKCIVKITGEMVLSFPAGITR
Sbjct: 541 TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGADPSKCIVKITGEMVLSFPAGITR 600
Query: 601 HFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQNDANTKEFWVNMPNLMTHLKKVS 660
HFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQNDANTKEFWVNMPNLMTHLKKVS
Sbjct: 601 HFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQNDANTKEFWVNMPNLMTHLKKVS 660
Query: 661 EQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDLRIDYKYNTDAMTTAVAL 720
EQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDLRIDYKYNTDAMTTAVAL
Sbjct: 661 EQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDLRIDYKYNTDAMTTAVAL 720
Query: 721 NNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKSENGGVGSLLARFQLSEG 780
NNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKSENGGVGSLLARFQLSEG
Sbjct: 721 NNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKSENGGVGSLLARFQLSEG 780
Query: 781 PSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKKRFAAGKYLADN 828
PSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKKRFAAGKYLADN
Sbjct: 781 PSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKKRFAAGKYLADN 828
>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
Length = 777
Score = 480 bits (1235), Expect = e-135
Identities = 251/424 (59%), Positives = 304/424 (71%), Gaps = 29/424 (6%)
Query: 408 RATPPPPPPPTYRTVVSSP--GPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRP 465
+ + PP T + P GP ++ +SS ARP TPL S PPPRP
Sbjct: 378 KPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPL----SVGTIVPPPRP 433
Query: 466 PSRPKLPPGK-PGVGDVSRPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAATTPTV 523
SRPKL GK G+ ++ RPFSPP+ S+ SPPP APLARAES+SSISS+ SLSAA TPTV
Sbjct: 434 ASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTV 493
Query: 524 ENEQPSLVWFDRGKFYLTFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGADPSKCI 583
G SRGPSP+++G QDTLPVA A TE+VNAYFKGADP+KCI
Sbjct: 494 --------------------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCI 533
Query: 584 VKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQNDANTK 643
VKITG+M +SFP+GI + F +NP+PA L FRV N SRLE +LPN QL+ D +Q D+NTK
Sbjct: 534 VKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTK 593
Query: 644 EFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDL 703
+FW+NM + +LKK+SEQ P A+YYNVD+LKYQVS+ GIQSTPLNLA W+C S+TDL
Sbjct: 594 DFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDL 653
Query: 704 RIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKS 763
R+DYKYN +AM L+N+Q +VP+DGGVT +Q+ LPPA+WNAEQ + WK+ IS+KS
Sbjct: 654 RVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQS-LPPAIWNAEQMKAFWKLSSISEKS 712
Query: 764 ENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKKRFAAGK 823
ENGG GSL A+F LSEGPSKP+ L VQF SEGSTLSG D ELVG GYR SLIKKRFA G+
Sbjct: 713 ENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGR 772
Query: 824 YLAD 827
YLAD
Sbjct: 773 YLAD 776
Score = 128 bits (321), Expect = 2e-29
Identities = 113/360 (31%), Positives = 150/360 (41%), Gaps = 108/360 (30%)
Query: 2 MEGLKKRTRKAF---GIRKKEKDTDSTGSPDRDGIQPSPHEPPYNSKAECAREGGKKVSK 58
+EG+K R RK F GI KKEKD +S PD D +
Sbjct: 246 VEGIKPRKRKTFALPGIIKKEKDAESVECPDADSL------------------------- 280
Query: 59 KSNGAPNGFYAEIDWERYNSPELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKF 117
N P++DEEGYSI+PE TK HFYSSS+S+ E+E KK+
Sbjct: 281 ------------------NIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKY 322
Query: 118 NIKIKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPR 177
I+IKP+ + A++DELK SIGNI LSP+ R SP + RNLS+EE+ + +
Sbjct: 323 RIEIKPMHPNNSHHTMASLDELKVSIGNITLSPA----ISRHSPVQMNRNLSNEELTKSK 378
Query: 178 RSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESP 237
S P E K D A PLFGP L+S+ T S S
Sbjct: 379 PSAPPNE----KGTSDLLAWDPLFGPSLDSSSSSSLT------------------SSSSA 416
Query: 238 KLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGP 297
+ T P GT P PP+ PA+ P+ LT G KL IN++ F P
Sbjct: 417 RPTTPLSVGTIVP-PPR--PASRPK----LTSG-------------KLSGINEIPRPFSP 456
Query: 298 VLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGP 357
++ S+TSP P + + A++P G P P
Sbjct: 457 PVT---------------SNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSP 501
>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
Length = 810
Score = 480 bits (1235), Expect = e-135
Identities = 251/424 (59%), Positives = 304/424 (71%), Gaps = 29/424 (6%)
Query: 408 RATPPPPPPPTYRTVVSSP--GPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRP 465
+ + PP T + P GP ++ +SS ARP TPL S PPPRP
Sbjct: 411 KPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPL----SVGTIVPPPRP 466
Query: 466 PSRPKLPPGK-PGVGDVSRPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAATTPTV 523
SRPKL GK G+ ++ RPFSPP+ S+ SPPP APLARAES+SSISS+ SLSAA TPTV
Sbjct: 467 ASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTV 526
Query: 524 ENEQPSLVWFDRGKFYLTFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGADPSKCI 583
G SRGPSP+++G QDTLPVA A TE+VNAYFKGADP+KCI
Sbjct: 527 --------------------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCI 566
Query: 584 VKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQNDANTK 643
VKITG+M +SFP+GI + F +NP+PA L FRV N SRLE +LPN QL+ D +Q D+NTK
Sbjct: 567 VKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTK 626
Query: 644 EFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDL 703
+FW+NM + +LKK+SEQ P A+YYNVD+LKYQVS+ GIQSTPLNLA W+C S+TDL
Sbjct: 627 DFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDL 686
Query: 704 RIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKS 763
R+DYKYN +AM L+N+Q +VP+DGGVT +Q+ LPPA+WNAEQ + WK+ IS+KS
Sbjct: 687 RVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQS-LPPAIWNAEQMKAFWKLSSISEKS 745
Query: 764 ENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKKRFAAGK 823
ENGG GSL A+F LSEGPSKP+ L VQF SEGSTLSG D ELVG GYR SLIKKRFA G+
Sbjct: 746 ENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGR 805
Query: 824 YLAD 827
YLAD
Sbjct: 806 YLAD 809
Score = 128 bits (321), Expect = 2e-29
Identities = 113/360 (31%), Positives = 150/360 (41%), Gaps = 108/360 (30%)
Query: 2 MEGLKKRTRKAF---GIRKKEKDTDSTGSPDRDGIQPSPHEPPYNSKAECAREGGKKVSK 58
+EG+K R RK F GI KKEKD +S PD D +
Sbjct: 279 VEGIKPRKRKTFALPGIIKKEKDAESVECPDADSL------------------------- 313
Query: 59 KSNGAPNGFYAEIDWERYNSPELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKF 117
N P++DEEGYSI+PE TK HFYSSS+S+ E+E KK+
Sbjct: 314 ------------------NIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKY 355
Query: 118 NIKIKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPR 177
I+IKP+ + A++DELK SIGNI LSP+ R SP + RNLS+EE+ + +
Sbjct: 356 RIEIKPMHPNNSHHTMASLDELKVSIGNITLSPA----ISRHSPVQMNRNLSNEELTKSK 411
Query: 178 RSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESP 237
S P E K D A PLFGP L+S+ T S S
Sbjct: 412 PSAPPNE----KGTSDLLAWDPLFGPSLDSSSSSSLT------------------SSSSA 449
Query: 238 KLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGP 297
+ T P GT P PP+ PA+ P+ LT G KL IN++ F P
Sbjct: 450 RPTTPLSVGTIVP-PPR--PASRPK----LTSG-------------KLSGINEIPRPFSP 489
Query: 298 VLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGP 357
++ S+TSP P + + A++P G P P
Sbjct: 490 PVT---------------SNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSP 534
>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
Length = 839
Score = 312 bits (800), Expect = 7e-85
Identities = 201/548 (36%), Positives = 288/548 (52%), Gaps = 47/548 (8%)
Query: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPAD---SPAPGPLGPPGPTGP---------PG 362
F D P + P +P +P+ A + A + PPGP G G
Sbjct: 299 FDDEEPRKFYVHIKPAP-ARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAG 357
Query: 363 PPGPPRNVLSPLNLEEVQKKVAEQTFIKDDY---LETISSPKDF----GLGQRATPPP-- 413
P PR+ +P ++ +E+ K+ + LE+ +DF LG ++P P
Sbjct: 358 KPQRPRS--APRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 415
Query: 414 --PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPP------PPPPRP 465
P + + SP + PGP S P P +P CR+ P PP P
Sbjct: 416 SSSPENVEDSGLDSPSHAA-PGPSPDSWVPRPGTPQSP-PSCRAPPPEARGIRAPPLPDS 473
Query: 466 PSRPKLPPGKPGV-----GDVS-RPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAA 518
P PG G+ GD+ P P + PP +R S S LS +
Sbjct: 474 PQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRS 533
Query: 519 TTPTVENEQPSLVWFDRGKFYL-TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGA 577
+P+ + +R F T G SRGPSP+ +G+QD LP+A AFTE V+AYF+G
Sbjct: 534 LSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGH 593
Query: 578 DPSKCIVKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQ 637
PS C+ ++TGE+ ++FPAGI R F+ P P L+FR+++ + +EH PN LL D +Q
Sbjct: 594 SPS-CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQ 652
Query: 638 NDANTKEFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCE 697
+D TK+FW+NM L L++ +EQ P A+YYNV +L+YQ S G QS PL L+ +W+C
Sbjct: 653 SDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCG 712
Query: 698 PSSTDLRIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIP 757
+ T + ++Y Y A L NVQ L+P+ VT ++ + P A WN E++R+ W++P
Sbjct: 713 ATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVR-LQPAATWNLEEKRLTWRLP 771
Query: 758 DISQKSENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKK 817
D+ SE GG G L A ++ GPS PSP+ QFTSEG+TLSG D+ELVG+GYR SL+K+
Sbjct: 772 DV---SEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKR 828
Query: 818 RFAAGKYL 825
RFA G YL
Sbjct: 829 RFATGMYL 836
Score = 84.3 bits (207), Expect = 4e-16
Identities = 81/294 (27%), Positives = 127/294 (43%), Gaps = 40/294 (13%)
Query: 79 PELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSK-DILKNAATV 136
PE+DEEG+++RP+ ST +SSS+S+ ++E +KF + IKP ++ A
Sbjct: 268 PEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAA 327
Query: 137 DELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRR--STPTPELISKKPPDDT 194
+L+A+ G++ L P P G +KR+ S + +P+R S P +++ +
Sbjct: 328 AQLRATAGSLILPPGP--------GGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEE 379
Query: 195 TALAPLFGPPLESAFDEQ-----KTEVLLDQPEIWGSGQPIN---PSMESPKLTRPFP-- 244
LFGPPLESAFD + + P + S P N ++SP P P
Sbjct: 380 QVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSP 439
Query: 245 -TGTPPPLPPKNVPA--TPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSP 301
+ P P P++ P+ PP + P D + + P L+++ G L P
Sbjct: 440 DSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPD---SPQPLASSPGPWGLEALAGGDLMP 496
Query: 302 KSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNP--ADSPAPGPLG 353
A E P R + VS P T N + S +P PLG
Sbjct: 497 APADPTAREGL----------AAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 540
>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 312 bits (800), Expect = 7e-85
Identities = 201/548 (36%), Positives = 288/548 (52%), Gaps = 47/548 (8%)
Query: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPAD---SPAPGPLGPPGPTGP---------PG 362
F D P + P +P +P+ A + A + PPGP G G
Sbjct: 349 FDDEEPRKFYVHIKPAP-ARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAG 407
Query: 363 PPGPPRNVLSPLNLEEVQKKVAEQTFIKDDY---LETISSPKDF----GLGQRATPPP-- 413
P PR+ +P ++ +E+ K+ + LE+ +DF LG ++P P
Sbjct: 408 KPQRPRS--APRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 465
Query: 414 --PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPP------PPPPRP 465
P + + SP + PGP S P P +P CR+ P PP P
Sbjct: 466 SSSPENVEDSGLDSPSHAA-PGPSPDSWVPRPGTPQSP-PSCRAPPPEARGIRAPPLPDS 523
Query: 466 PSRPKLPPGKPGV-----GDVS-RPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAA 518
P PG G+ GD+ P P + PP +R S S LS +
Sbjct: 524 PQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRS 583
Query: 519 TTPTVENEQPSLVWFDRGKFYL-TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGA 577
+P+ + +R F T G SRGPSP+ +G+QD LP+A AFTE V+AYF+G
Sbjct: 584 LSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGH 643
Query: 578 DPSKCIVKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQ 637
PS C+ ++TGE+ ++FPAGI R F+ P P L+FR+++ + +EH PN LL D +Q
Sbjct: 644 SPS-CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQ 702
Query: 638 NDANTKEFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCE 697
+D TK+FW+NM L L++ +EQ P A+YYNV +L+YQ S G QS PL L+ +W+C
Sbjct: 703 SDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCG 762
Query: 698 PSSTDLRIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIP 757
+ T + ++Y Y A L NVQ L+P+ VT ++ + P A WN E++R+ W++P
Sbjct: 763 ATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVR-LQPAATWNLEEKRLTWRLP 821
Query: 758 DISQKSENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKK 817
D+ SE GG G L A ++ GPS PSP+ QFTSEG+TLSG D+ELVG+GYR SL+K+
Sbjct: 822 DV---SEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKR 878
Query: 818 RFAAGKYL 825
RFA G YL
Sbjct: 879 RFATGMYL 886
Score = 84.3 bits (207), Expect = 4e-16
Identities = 81/294 (27%), Positives = 127/294 (43%), Gaps = 40/294 (13%)
Query: 79 PELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSK-DILKNAATV 136
PE+DEEG+++RP+ ST +SSS+S+ ++E +KF + IKP ++ A
Sbjct: 318 PEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAA 377
Query: 137 DELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRR--STPTPELISKKPPDDT 194
+L+A+ G++ L P P G +KR+ S + +P+R S P +++ +
Sbjct: 378 AQLRATAGSLILPPGP--------GGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEE 429
Query: 195 TALAPLFGPPLESAFDEQ-----KTEVLLDQPEIWGSGQPIN---PSMESPKLTRPFP-- 244
LFGPPLESAFD + + P + S P N ++SP P P
Sbjct: 430 QVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSP 489
Query: 245 -TGTPPPLPPKNVPA--TPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSP 301
+ P P P++ P+ PP + P D + + P L+++ G L P
Sbjct: 490 DSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPD---SPQPLASSPGPWGLEALAGGDLMP 546
Query: 302 KSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNP--ADSPAPGPLG 353
A E P R + VS P T N + S +P PLG
Sbjct: 547 APADPTAREGL----------AAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 590
>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 312 bits (800), Expect = 7e-85
Identities = 201/548 (36%), Positives = 288/548 (52%), Gaps = 47/548 (8%)
Query: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPAD---SPAPGPLGPPGPTGP---------PG 362
F D P + P +P +P+ A + A + PPGP G G
Sbjct: 349 FDDEEPRKFYVHIKPAP-ARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAG 407
Query: 363 PPGPPRNVLSPLNLEEVQKKVAEQTFIKDDY---LETISSPKDF----GLGQRATPPP-- 413
P PR+ +P ++ +E+ K+ + LE+ +DF LG ++P P
Sbjct: 408 KPQRPRS--APRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 465
Query: 414 --PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPP------PPPPRP 465
P + + SP + PGP S P P +P CR+ P PP P
Sbjct: 466 SSSPENVEDSGLDSPSHAA-PGPSPDSWVPRPGTPQSP-PSCRAPPPEARGIRAPPLPDS 523
Query: 466 PSRPKLPPGKPGV-----GDVS-RPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAA 518
P PG G+ GD+ P P + PP +R S S LS +
Sbjct: 524 PQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRS 583
Query: 519 TTPTVENEQPSLVWFDRGKFYL-TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGA 577
+P+ + +R F T G SRGPSP+ +G+QD LP+A AFTE V+AYF+G
Sbjct: 584 LSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGH 643
Query: 578 DPSKCIVKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQ 637
PS C+ ++TGE+ ++FPAGI R F+ P P L+FR+++ + +EH PN LL D +Q
Sbjct: 644 SPS-CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQ 702
Query: 638 NDANTKEFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCE 697
+D TK+FW+NM L L++ +EQ P A+YYNV +L+YQ S G QS PL L+ +W+C
Sbjct: 703 SDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCG 762
Query: 698 PSSTDLRIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIP 757
+ T + ++Y Y A L NVQ L+P+ VT ++ + P A WN E++R+ W++P
Sbjct: 763 ATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVR-LQPAATWNLEEKRLTWRLP 821
Query: 758 DISQKSENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKK 817
D+ SE GG G L A ++ GPS PSP+ QFTSEG+TLSG D+ELVG+GYR SL+K+
Sbjct: 822 DV---SEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKR 878
Query: 818 RFAAGKYL 825
RFA G YL
Sbjct: 879 RFATGMYL 886
Score = 84.3 bits (207), Expect = 4e-16
Identities = 81/294 (27%), Positives = 127/294 (43%), Gaps = 40/294 (13%)
Query: 79 PELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSK-DILKNAATV 136
PE+DEEG+++RP+ ST +SSS+S+ ++E +KF + IKP ++ A
Sbjct: 318 PEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAA 377
Query: 137 DELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRR--STPTPELISKKPPDDT 194
+L+A+ G++ L P P G +KR+ S + +P+R S P +++ +
Sbjct: 378 AQLRATAGSLILPPGP--------GGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEE 429
Query: 195 TALAPLFGPPLESAFDEQ-----KTEVLLDQPEIWGSGQPIN---PSMESPKLTRPFP-- 244
LFGPPLESAFD + + P + S P N ++SP P P
Sbjct: 430 QVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSP 489
Query: 245 -TGTPPPLPPKNVPA--TPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSP 301
+ P P P++ P+ PP + P D + + P L+++ G L P
Sbjct: 490 DSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPD---SPQPLASSPGPWGLEALAGGDLMP 546
Query: 302 KSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNP--ADSPAPGPLG 353
A E P R + VS P T N + S +P PLG
Sbjct: 547 APADPTAREGL----------AAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 590
>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
Length = 891
Score = 306 bits (784), Expect = 5e-83
Identities = 198/543 (36%), Positives = 285/543 (52%), Gaps = 47/543 (8%)
Query: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPAD---SPAPGPLGPPGPTGP---------PG 362
F D P + P +P +P+ A + A + PPGP G G
Sbjct: 349 FDDEEPRKFYVHIKPAP-ARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAG 407
Query: 363 PPGPPRNVLSPLNLEEVQKKVAEQTFIKDDY---LETISSPKDF----GLGQRATPPP-- 413
P PR+ +P ++ +E+ K+ + LE+ +DF LG ++P P
Sbjct: 408 KPQRPRS--APRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 465
Query: 414 --PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPP------PPPPRP 465
P + + SP + PGP S P P +P CR+ P PP P
Sbjct: 466 SSSPENVEDSGLDSPSHAA-PGPSPDSWVPRPGTPQSP-PSCRAPPPEARGIRAPPLPDS 523
Query: 466 PSRPKLPPGKPGV-----GDVS-RPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAA 518
P PG G+ GD+ P P + PP +R S S LS +
Sbjct: 524 PQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRS 583
Query: 519 TTPTVENEQPSLVWFDRGKFYL-TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGA 577
+P+ + +R F T G SRGPSP+ +G+QD LP+A AFTE V+AYF+G
Sbjct: 584 LSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGH 643
Query: 578 DPSKCIVKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQ 637
PS C+ ++TGE+ ++FPAGI R F+ P P L+FR+++ + +EH PN LL D +Q
Sbjct: 644 SPS-CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQ 702
Query: 638 NDANTKEFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCE 697
+D TK+FW+NM L L++ +EQ P A+YYNV +L+YQ S G QS PL L+ +W+C
Sbjct: 703 SDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCG 762
Query: 698 PSSTDLRIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIP 757
+ T + ++Y Y A L NVQ L+P+ VT ++ + P A WN E++R+ W++P
Sbjct: 763 ATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVR-LQPAATWNLEEKRLTWRLP 821
Query: 758 DISQKSENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKK 817
D+ SE GG G L A ++ GPS PSP+ QFTSEG+TLSG D+ELVG+GYR SL+K+
Sbjct: 822 DV---SEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKR 878
Query: 818 RFA 820
RFA
Sbjct: 879 RFA 881
Score = 84.3 bits (207), Expect = 4e-16
Identities = 81/294 (27%), Positives = 127/294 (43%), Gaps = 40/294 (13%)
Query: 79 PELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSK-DILKNAATV 136
PE+DEEG+++RP+ ST +SSS+S+ ++E +KF + IKP ++ A
Sbjct: 318 PEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAA 377
Query: 137 DELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRR--STPTPELISKKPPDDT 194
+L+A+ G++ L P P G +KR+ S + +P+R S P +++ +
Sbjct: 378 AQLRATAGSLILPPGP--------GGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEE 429
Query: 195 TALAPLFGPPLESAFDEQ-----KTEVLLDQPEIWGSGQPIN---PSMESPKLTRPFP-- 244
LFGPPLESAFD + + P + S P N ++SP P P
Sbjct: 430 QVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSP 489
Query: 245 -TGTPPPLPPKNVPA--TPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSP 301
+ P P P++ P+ PP + P D + + P L+++ G L P
Sbjct: 490 DSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPD---SPQPLASSPGPWGLEALAGGDLMP 546
Query: 302 KSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNP--ADSPAPGPLG 353
A E P R + VS P T N + S +P PLG
Sbjct: 547 APADPTAREGL----------AAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 590
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 84.7 bits (208), Expect = 3e-16
Identities = 100/396 (25%), Positives = 129/396 (32%), Gaps = 67/396 (16%)
Query: 149 SPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAP----LFGPP 204
+PSP +P P + + + P +T TP + P TT P PP
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457
Query: 205 LESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTG 264
+ + T P S PS + T P PT TP P P P TPP
Sbjct: 1458 ISTTTTPPPTTTP-SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP--PTTTPITPP--A 1512
Query: 265 SPLTIGPGNDQSA-TEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHV 323
S T+ P S T P+ P+ P S T P
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT------------TLPPTT 1560
Query: 324 TPELTPREKVVSPPATPDNPADSPAPGP----LGPPGPTGPPGPPG------PPRNVLSP 373
TP P PP T +P + P P P PT P PP PP SP
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620
Query: 374 LNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPG 433
+ + T L TP PPP T ++P P + P
Sbjct: 1621 PTTTPITPPTSTTT-----------------LPPTTTPSPPP-----TTTTTPPPTTTPS 1658
Query: 434 PGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSS 493
P TT+ S P +TT PPP PS P P ++ P SP SS
Sbjct: 1659 PPTTTTPSPPI----------TTTTTPPPTTTPSSPITTTPSPPTTTMTTP-SPTTTPSS 1707
Query: 494 PPPIAPLARAESTSSISSTNSLSAATTPTVENEQPS 529
PI ST++ S + +PT P+
Sbjct: 1708 --PITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741
Score = 75.9 bits (185), Expect = 1e-13
Identities = 101/375 (26%), Positives = 119/375 (31%), Gaps = 63/375 (16%)
Query: 176 PRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPIN-PSM 234
P +TP+P + PP TT P P T + P + P PS
Sbjct: 1472 PPTTTPSPPTTTPSPPTTTTTTPPPTTTP------SPPTTTPITPPASTTTLPPTTTPSP 1525
Query: 235 ESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSI 294
+ T P PT TP P P P TPP S T+ P S P
Sbjct: 1526 PTTTTTTPPPTTTPSP--PTTTPITPPT--STTTLPPTTTPSPPPTTTTTPP-------- 1573
Query: 295 FGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGP 354
P +P + T P TP PP T +P P P+ P
Sbjct: 1574 --PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP---PTTTPITP 1628
Query: 355 PG------PTGPPGPPG------PPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKD 402
P PT P PP PP SP + T T SSP
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT--TPPPTTTPSSP-- 1684
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPP 462
T P PP T T P P TT P+ P T STT P PP
Sbjct: 1685 ------ITTTPSPPTTTMTT---------PSPTTT-----PSSPITTTTTPSSTTTPSPP 1724
Query: 463 PRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPT 522
P + P P P + PP +SSP PL T S S + TTP
Sbjct: 1725 PTTMTTPS-PTTTPSPPTTTMTTLPPTTTSSPLTTTPLP-PSITPPTFSPFSTTTPTTPC 1782
Query: 523 VENEQPSLVWFDRGK 537
V + W D GK
Sbjct: 1783 VPLCNWT-GWLDSGK 1796
Score = 62.0 bits (149), Expect = 2e-09
Identities = 59/206 (28%), Positives = 80/206 (38%), Gaps = 45/206 (21%)
Query: 329 PREKVVSPPATPDNPADSPAPGPLGPPG--PTGPPGPPGPPRNVLSPLNLEEVQKKVAEQ 386
P +K ++ TP P +P+P P PT P PP P
Sbjct: 1391 PMDKCIT---TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPT------------ 1435
Query: 387 TFIKDDYLETISSPKDFGLGQRATPPP---PPPPTYRTVVSSPGPGSGPGPGTTSGASSP 443
T SP + TPPP P PP T ++P P + P P TT+ P
Sbjct: 1436 ---------TTPSPP---ITTTTTPPPTTTPSPPISTT--TTPPPTTTPSPPTTT----P 1477
Query: 444 ARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPF----SPPIHSSSPPPIAP 499
+ P T P +TT PPP PS P P P + P SPP +++ PP
Sbjct: 1478 SPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTT 1537
Query: 500 LARAESTSSI---SSTNSLSAATTPT 522
+T+ I +ST +L TTP+
Sbjct: 1538 TPSPPTTTPITPPTSTTTLPPTTTPS 1563
Score = 56.2 bits (134), Expect = 1e-07
Identities = 87/372 (23%), Positives = 124/372 (33%), Gaps = 38/372 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3957 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4016
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 4017 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 4074
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 4075 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4134
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 4135 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4188
Query: 403 FGLGQRATPPP--PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPP 460
G + PP P S+P P S P T+ SSP +T L+ ST PP
Sbjct: 4189 TPTGTQTGPPTHTSTAPIAELTTSNPPPESST-PQTSRSTSSPLTESTTLL---STLPPA 4244
Query: 461 ---PPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSA 517
PPS P P G SPP +++ PP P + SS + T S
Sbjct: 4245 IEMTSTAPPSTPTAPTTTSG----GHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQ 4300
Query: 518 ATTPTVENEQPS 529
TT + P+
Sbjct: 4301 TTTTSAWTPTPT 4312
Score = 51.6 bits (122), Expect = 3e-06
Identities = 75/312 (24%), Positives = 107/312 (34%), Gaps = 38/312 (12%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 4026 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 4086 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 4143
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADS 346
G P+ + +V T+P T +TP +P T P
Sbjct: 4144 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTGPPTH 4200
Query: 347 PAPGPLGPPGPTGPPGPPGPP---RNVLSPLN----LEEVQKKVAEQTFIKDDYLETISS 399
+ P+ + PP P R+ SPL L E T T ++
Sbjct: 4201 TSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP--STPTA 4258
Query: 400 PKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPP 459
P G +PPP T S PG P GTT+G+SS P+T V +T+
Sbjct: 4259 PTTTSGGHTLSPPPS------TTTSPPGT---PTRGTTTGSSSAPTPST--VQTTTTSAW 4307
Query: 460 PPPPRPPSRPKL 471
P P P S P +
Sbjct: 4308 TPTPTPLSTPSI 4319
Score = 47.0 bits (110), Expect = 7e-05
Identities = 83/375 (22%), Positives = 121/375 (32%), Gaps = 32/375 (8%)
Query: 176 PRRSTPTPELISK-KPPDDTTALAPLFGP-PLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
P +TP+P + PP TT L P P P + P PI +
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT 1672
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT-IGPGNDQSATEVKIEKLPSINDLD 292
P T P T P PP TP T +P + I S+T ++
Sbjct: 1673 TTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS 1732
Query: 293 SIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPA-------- 344
P SP + + S + + P +TP TP P
Sbjct: 1733 PTTTP--SPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTG 1790
Query: 345 --DSPAPGPLGPPGPT---GPPGPPGPPRNVLSPLNL-EEVQKKVAEQTFIKDDYLETIS 398
DS P P G T G PG N+ + +V QT + D + I
Sbjct: 1791 WLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLIC 1850
Query: 399 SPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTP 458
+D G P Y V + P TT+ +P P T + +T
Sbjct: 1851 KNEDQKPG--GVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVT 1908
Query: 459 PPPPPRPPSRPKLPP--------GKPGVGDVSRPFSPPIHSS---SPPPIAPLARAESTS 507
P P P P P P P + PI ++ +P P + +T+
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1968
Query: 508 SISSTNSLSAATTPT 522
I++T +++ TPT
Sbjct: 1969 PITTTTTVTPTPTPT 1983
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 1979 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2038
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2039 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2096
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2156
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2157 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2210
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2211 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 2267
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 2268 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2327
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPT 2351
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2131 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2188
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2249 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2302
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2303 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 2359
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 2360 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2419
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPT 2443
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2223 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2280
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2340
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2341 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2394
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2395 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 2451
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2511
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPT 2535
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2315 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2372
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2432
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2433 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2486
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2487 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 2543
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 2544 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2603
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPT 2627
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2407 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2464
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2525 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2578
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2579 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 2635
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 2636 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2695
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPT 2719
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2499 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2556
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2616
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2617 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2670
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2671 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 2727
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 2728 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2787
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPT 2811
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2591 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2648
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2709 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2763 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 2819
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 2820 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2879
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 2880 TGTQTPTTTPITTTTTVTPTPTPT 2903
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2683 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2740
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2801 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2854
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2855 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 2911
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 2912 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2971
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPT 2995
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2775 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2832
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2893 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2946
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 2947 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3003
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3063
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3064 TGTQTPTTTPITTTTTVTPTPTPT 3087
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2867 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2924
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2985 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3038
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3039 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3095
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3096 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3155
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPT 3179
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3016
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3076
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3077 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3130
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3131 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3187
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3188 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3247
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPT 3271
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3051 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3108
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3169 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3222
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3223 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3279
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3339
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPT 3363
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3143 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3200
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3261 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3314
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3315 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3371
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3372 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3431
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3432 TGTQTPTTTPITTTTTVTPTPTPT 3455
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3235 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3292
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3352
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3353 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3406
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3407 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3463
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3464 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3523
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3524 TGTQTPTTTPITTTTTVTPTPTPT 3547
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3327 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3384
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3445 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3498
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3499 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3555
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3556 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3615
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPT 3639
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3419 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3476
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3536
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3537 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3591 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3647
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3648 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3707
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3708 TGTQTPTTTPITTTTTVTPTPTPT 3731
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3511 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3568
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3629 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3682
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3683 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3739
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3740 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3799
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPT 3823
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3603 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3660
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3720
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3721 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3774
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3775 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3831
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3832 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3891
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPT 3915
Score = 46.6 bits (109), Expect = 9e-05
Identities = 82/384 (21%), Positives = 126/384 (32%), Gaps = 52/384 (13%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3695 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3752
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3812
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3813 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3866
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPAT 448
G + TP P T TV +P P P TT +G +P T
Sbjct: 3867 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 3923
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIA 498
P+ + TP P P + P P P + PI ++ +P P
Sbjct: 3924 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3983
Query: 499 PLARAESTSSISSTNSLSAATTPT 522
+ +T+ I++T +++ TPT
Sbjct: 3984 TGTQTPTTTPITTTTTVTPTPTPT 4007
Score = 46.2 bits (108), Expect = 1e-04
Identities = 66/299 (22%), Positives = 102/299 (34%), Gaps = 40/299 (13%)
Query: 245 TGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFG-------P 297
T T P PP P T T +P T P Q+ T I ++ + G P
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1946
Query: 298 VLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNPADSPAPGPLGP 354
+ + +V T+P T +TP +P TP + P P
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-- 2004
Query: 355 PGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKDFGLGQRATPPP 413
PTG P P + + + QT T + +P G + TP
Sbjct: 2005 --PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2059
Query: 414 PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLP- 472
P T TV +P P +G +P TP+ + TP P P + P
Sbjct: 2060 TPITTTTTVTPTPTP---------TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPI 2108
Query: 473 ------PGKPGVGDVSRPFSPPIHSS---SPPPIAPLARAESTSSISSTNSLSAATTPT 522
P P + PI ++ +P P + +T+ I++T +++ TPT
Sbjct: 2109 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2167
Score = 45.4 bits (106), Expect = 2e-04
Identities = 81/380 (21%), Positives = 124/380 (32%), Gaps = 51/380 (13%)
Query: 181 PTPELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESP 237
PTP + P TT + P G + T + P G+ P + +
Sbjct: 1893 PTPPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1950
Query: 238 KLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFG- 296
P PT T P P T T +P T P Q+ T I ++ + G
Sbjct: 1951 TTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2008
Query: 297 ------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNPADSP 347
P+ + +V T+P T +TP +P TP +
Sbjct: 2009 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2068
Query: 348 APGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKDFGLG 406
P P PTG P P + + + QT T + +P G
Sbjct: 2069 TPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2122
Query: 407 QRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------------SGASSPARPATPLVP 452
+ TP P T TV +P P P TT +G +P TP+
Sbjct: 2123 TQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITT 2179
Query: 453 CRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS---SPPPIAPLAR 502
+ TP P P + P P P + PI ++ +P P +
Sbjct: 2180 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2239
Query: 503 AESTSSISSTNSLSAATTPT 522
+T+ I++T +++ TPT
Sbjct: 2240 TPTTTPITTTTTVTPTPTPT 2259
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 1910 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1969
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 1970 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2027
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2028 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2087
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2088 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2141
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2142 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2200
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2201 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2257
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2258 PTGTQTPT 2265
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 1933 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2050
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2111 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2164
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2165 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2223
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2224 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2280
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2281 PTGTQTPT 2288
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 1956 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2016 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2073
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2134 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2188 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2246
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2247 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2303
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2304 PTGTQTPT 2311
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2002 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2119
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2120 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2179
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2180 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2234 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2293 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2349
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2350 PTGTQTPT 2357
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2025 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2084
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2085 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2142
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2203 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2257 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2315
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2316 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2372
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2373 PTGTQTPT 2380
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2048 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2107
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2108 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2165
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2225
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2226 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2280 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2338
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2339 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2395
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2396 PTGTQTPT 2403
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2211
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2271
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2272 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2325
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2326 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2384
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2385 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2441
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2442 PTGTQTPT 2449
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2177 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2234
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2294
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2295 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2348
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2349 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2407
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2408 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2464
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2465 PTGTQTPT 2472
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2140 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2200 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2257
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2258 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2317
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2318 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2371
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2372 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2431 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2487
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2488 PTGTQTPT 2495
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2186 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2246 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2303
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2363
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2364 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2418 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2533
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2534 PTGTQTPT 2541
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2269 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2326
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2386
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2387 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2441 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2556
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2557 PTGTQTPT 2564
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2232 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2349
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2410 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2464 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2523 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2579
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2580 PTGTQTPT 2587
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2338 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2395
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2455
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2456 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2509
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2510 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2569 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2625
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2626 PTGTQTPT 2633
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2361 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2418
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2479 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2532
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2533 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2591
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2648
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2649 PTGTQTPT 2656
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2384 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2441
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2501
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2502 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2556 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2671
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2672 PTGTQTPT 2679
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2370 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2429
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2430 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2487
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2548 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2601
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2602 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2660
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2661 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2717
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2718 PTGTQTPT 2725
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2393 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2453 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2510
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2570
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2571 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2624
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2625 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2683
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2684 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2740
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2741 PTGTQTPT 2748
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2533
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2594 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2648 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2763
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2764 PTGTQTPT 2771
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2579
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2639
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2640 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2693
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2694 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2753 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2809
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2810 PTGTQTPT 2817
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2545 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2602
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2663 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2716
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2717 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2776 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2832
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2833 PTGTQTPT 2840
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2568 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2625
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2686 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2739
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2740 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2799 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2855
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2856 PTGTQTPT 2863
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2671
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2732 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2785
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2786 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2901
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2902 PTGTQTPT 2909
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2637 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2694
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2754
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2755 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2808
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2809 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2867
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2868 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2924
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2925 PTGTQTPT 2932
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2660 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2717
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2777
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2778 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2831
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2832 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2891 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2947
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2948 PTGTQTPT 2955
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2706 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2763
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2824 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2877
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2878 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2937 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 2993
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 2994 PTGTQTPT 3001
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2729 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2786
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2847 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2901 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3016
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3017 PTGTQTPT 3024
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2809
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2869
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2870 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2924 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 2983 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3039
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3040 PTGTQTPT 3047
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2798 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2855
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2915
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2916 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2969
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2970 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3028
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3029 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3085
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3086 PTGTQTPT 3093
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2878
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2939 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2992
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 2993 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3108
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3109 PTGTQTPT 3116
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2843
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2844 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2901
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 2962 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3016 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3131
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3132 PTGTQTPT 3139
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2947
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3007
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3008 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3061
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3062 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3177
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3178 PTGTQTPT 3185
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2913 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2970
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3031 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3084
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3085 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3143
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3144 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3200
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3201 PTGTQTPT 3208
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2936 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 2993
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3054 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3107
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3108 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3166
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3167 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3223
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3224 PTGTQTPT 3231
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2981
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 2982 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3039
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3100 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3153
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3154 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3213 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3269
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3270 PTGTQTPT 3277
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3005 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3062
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3123 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3177 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3236 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3292
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3293 PTGTQTPT 3300
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3027
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3028 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3085
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3146 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3199
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3200 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3259 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3315
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3316 PTGTQTPT 3323
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3131
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3191
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3192 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3246 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3361
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3362 PTGTQTPT 3369
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3096
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3154
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3214
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3215 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3268
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3269 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3328 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3384
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3385 PTGTQTPT 3392
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3120 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3177
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3238 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3291
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3292 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3351 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3407
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3408 PTGTQTPT 3415
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3166 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3223
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3284 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3337
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3338 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3453
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3454 PTGTQTPT 3461
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3189 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3246
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3307 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3360
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3361 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3420 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3476
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3477 PTGTQTPT 3484
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3212 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3269
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3329
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3330 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3383
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3384 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3443 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3499
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3500 PTGTQTPT 3507
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3258 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3315
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3376 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3429
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3430 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3489 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3545
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3546 PTGTQTPT 3553
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3281 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3338
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3399 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3453 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3511
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3512 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3568
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3569 PTGTQTPT 3576
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3304 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3361
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3421
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3422 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3475
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3476 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3535 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3591
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3592 PTGTQTPT 3599
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3350 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3407
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3467
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3468 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3521
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3522 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3581 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3637
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3638 PTGTQTPT 3645
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3373 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3430
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3490
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3491 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3544
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3545 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3604 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3660
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3661 PTGTQTPT 3668
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3396 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3453
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3514 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3568 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3627 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3683
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3684 PTGTQTPT 3691
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3499
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3559
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3560 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3613
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3614 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3673 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3729
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3730 PTGTQTPT 3737
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3465 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3522
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3583 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3636
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3637 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3695
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3696 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3752
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3753 PTGTQTPT 3760
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3488 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3545
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3605
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3606 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3659
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3660 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3719 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3775
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3776 PTGTQTPT 3783
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3534 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3591
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3652 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3705
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3706 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3765 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3821
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3822 PTGTQTPT 3829
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3557 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3614
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3675 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3728
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3729 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3788 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3844
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3845 PTGTQTPT 3852
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3579
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3580 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3637
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3698 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3751
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3752 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3810
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3811 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3867
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3868 PTGTQTPT 3875
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3626 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3683
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3744 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3797
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3798 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3913
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3914 PTGTQTPT 3921
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3648
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3649 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3706
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3766
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3767 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3820
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3821 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3936
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3937 PTGTQTPT 3944
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3672 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3729
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3790 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3843
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3844 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3903 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 3959
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 3960 PTGTQTPT 3967
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3717
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3718 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3775
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3835
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3836 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3890 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3949 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 4005
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 4006 PTGTQTPT 4013
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/368 (21%), Positives = 121/368 (32%), Gaps = 37/368 (10%)
Query: 180 TPTP---ELISKKPPDDTTALAPL---FGPPLESAFDEQKTEVLLDQPEIWGSGQPINPS 233
TPTP + + P TT + P G + T + P G+ P
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740
Query: 234 MESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
+ + P PT T P P T T +P T P Q+ T I ++ +
Sbjct: 3741 ITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 3798
Query: 294 IFG-------PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---SPPATPDNP 343
G P+ + +V T+P T +TP +P TP
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETIS-SPKD 402
+ P P PTG P P + + + QT T + +P
Sbjct: 3859 TTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3912
Query: 403 FGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT--------SGASSPARPATPLVPCR 454
G + TP P T TV +P P P TT + +P TP
Sbjct: 3913 TPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971
Query: 455 STTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNS 514
+TT P P+ + P P + +P + P P+ +T++++ T +
Sbjct: 3972 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPT 4028
Query: 515 LSAATTPT 522
+ TPT
Sbjct: 4029 PTGTQTPT 4036
Score = 43.9 bits (102), Expect = 6e-04
Identities = 84/377 (22%), Positives = 123/377 (32%), Gaps = 54/377 (14%)
Query: 176 PRRSTPTPELISKK-PPDDTTALAPLF---GPPLESAFDEQKTEVLLDQPEIWGSGQPIN 231
P +TP+P + + PP TT +P+ PP + T I + P +
Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTT--PSSPITTTTTPSS 1717
Query: 232 PSMESPK---LTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSI 288
+ SP +T P PT TP P P T SPLT P LP
Sbjct: 1718 TTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTP-------------LPP- 1763
Query: 289 NDLDSIFGPVLSPKSVAVNAEE-----KWVHFSDTSPEHVTPELTPREKVVSPPATPDNP 343
SI P SP S W + D+ + E ++ P
Sbjct: 1764 ----SITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTE-LIGDVCGPGWA 1818
Query: 344 ADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKK--VAEQTF-----IKDDYLET 396
A+ + P P G G + + E QK V F I E
Sbjct: 1819 ANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCEC 1878
Query: 397 ISSPKDFGLGQRATPPPP---PPPTYRTVVSSPGPGSGPGPGTT--------SGASSPAR 445
++ P P PP P T TV +P P P TT + +P
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1938
Query: 446 PATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAES 505
TP +TT P P+ + P P + +P + P P+ +
Sbjct: 1939 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT---T 1995
Query: 506 TSSISSTNSLSAATTPT 522
T++++ T + + TPT
Sbjct: 1996 TTTVTPTPTPTGTQTPT 2012
Score = 37.4 bits (85), Expect = 0.057
Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 7/88 (7%)
Query: 449 PLVPCRSTTPPP---PPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAES 505
P+ C +T PP P P P S LPP + +PP ++ PPI
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Query: 506 TSS----ISSTNSLSAATTPTVENEQPS 529
T++ IS+T + TTP+ PS
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPS 1478
Score = 35.4 bits (80), Expect = 0.22
Identities = 47/210 (22%), Positives = 72/210 (34%), Gaps = 29/210 (13%)
Query: 324 TPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKV 383
T T E P TP + P P PTG P P + + +
Sbjct: 1884 TMTTTTTENPTPPTTTPITTTTTVTPTPT----PTGTQTPTTTP--ITTTTTVTPTPTPT 1937
Query: 384 AEQTFIKDDYLETIS-SPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASS 442
QT T + +P G + TP P T TV +P P +G +
Sbjct: 1938 GTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTP---------TGTQT 1987
Query: 443 PARPATPLVPCRSTTPPPPPPRPPSRPKLP-------PGKPGVGDVSRPFSPPIHSS--- 492
P TP+ + TP P P + P P P + PI ++
Sbjct: 1988 PT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2045
Query: 493 SPPPIAPLARAESTSSISSTNSLSAATTPT 522
+P P + +T+ I++T +++ TPT
Sbjct: 2046 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2075
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 84.3 bits (207), Expect = 4e-16
Identities = 113/485 (23%), Positives = 167/485 (34%), Gaps = 93/485 (19%)
Query: 103 SSSESEEEEESHKKFNIKIKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPG 162
S SE+ +EE + K+ ++ + + + I+K K P P ++ P R P
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK---------PIPKQQGPGRDP- 229
Query: 163 AIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPE 222
+ TP+ IS + P+ + P G P++ +T D +
Sbjct: 230 --------------LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQT----DHAK 271
Query: 223 IWGSGQPINPSMESPKLTRPFPTGTPPPLP-PKNVPATPPRTGSPLTIGPGNDQSATEVK 281
+ P + + R P LP P P P G P PG+++S
Sbjct: 272 LPLQRDASRPQTKQADIVRG--ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP--- 326
Query: 282 IEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPD 341
GP P P +T L + V PP P
Sbjct: 327 --------------GPAKPP----------------AQPSGLTKPLAQQPGTVKPPVQPP 356
Query: 342 NPADSPAPGPLGPPGP----TGPPGP----PGPPRNVLSPLNLEEVQKKVAEQTFIKDDY 393
PA PLGP P TG P PGP P V K A+Q
Sbjct: 357 GTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGPKALAQPP----GVGKTPAQQPGPAKPP 411
Query: 394 LETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGP----GPGTTSG-ASSPARPAT 448
+ + +PK P P +T V PGPG P GPG TS + P +P
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-- 469
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSS 508
P + P PPP+ P K PP +PG ++P S S+ PPP P S
Sbjct: 470 ---PSQLPGPAKPPPQQPGPAKPPPQQPG---SAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523
Query: 509 ISSTNSLS---AATTPTVENEQPSLVWFDRGKFYLTFEGSSRGPSPLTMGAQDTLPVAAA 565
ST S + P+ + P+ + ++ GS + P T+ P +
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQG 583
Query: 566 FTETV 570
+T+
Sbjct: 584 LPKTI 588
Score = 50.4 bits (119), Expect = 7e-06
Identities = 83/385 (21%), Positives = 131/385 (34%), Gaps = 56/385 (14%)
Query: 149 SPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTP---------TPELISKKPPDDTTALAP 199
SP P + SP++ A K++LS + P++ P +P +K+PP+ + P
Sbjct: 676 SPQPQQTSPKKD-AAPKQDLS--KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 200 LFGPPLESAF--DEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVP 257
PP E + ++ K V D+P+ +P + S T T P +P V
Sbjct: 733 --APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT------TKPDIPSSKVQ 784
Query: 258 A-TPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFS 316
+ +T PL + EK+ D +I P K ++ H
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-DSKAIPRPASDSKIIS--------HPG 835
Query: 317 DTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNL 376
+S ++ P +K P +P P P P G P PPGP +
Sbjct: 836 PSSESKGQKQVDPVQK----KEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGT 436
+ K EQ S LG P P T + V+ G G +
Sbjct: 892 PQQSPKPQEQ-----------SRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFS 940
Query: 437 -------TSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPI 489
T+G P + P P + P PP PK P S P
Sbjct: 941 QASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET 1000
Query: 490 HSSSPPPIAPLARAESTSSISSTNS 514
+ + + P +AE ++ T +
Sbjct: 1001 KAPAAEKLEP--KAEQAPTVKRTET 1023
Score = 47.0 bits (110), Expect = 7e-05
Identities = 60/223 (26%), Positives = 77/223 (34%), Gaps = 33/223 (14%)
Query: 315 FSDTSPEHVTPELTPREKVVSPPATP---------DNPADSPAPGPLGPPGPTGPPGPPG 365
F P P +P V S PA P D A P P P PP P PP PP
Sbjct: 2367 FGQEKPASQLPSGSP--SVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Query: 366 P-------PRNVLSPLNLEEVQKKVAEQTFIKD--DYLETISSPKDFGLGQR---ATPPP 413
P P+ + P V V T + D LET + + GL T PP
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484
Query: 414 PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPP 473
P PP ++ S P P S P P++P TT P P P
Sbjct: 2485 PVPPKPSSIPSGLVFTHRPEP------SKPPIAPKPVIPQLPTTTQKPTDIHPK----PT 2534
Query: 474 GKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLS 516
G ++ P P +PL+ + SS + SL+
Sbjct: 2535 GLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT 2577
Score = 45.8 bits (107), Expect = 2e-04
Identities = 94/406 (23%), Positives = 135/406 (33%), Gaps = 67/406 (16%)
Query: 156 SPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPL--------ES 207
SP ++P S+ + R ++ T ++S D+T+ A L P + E
Sbjct: 2081 SPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEE 2140
Query: 208 AFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPL 267
DE T+ + EI ES LT P+ + +PP + P+ S
Sbjct: 2141 IEDEYVTDYTREIQEIIAH--------ESLILTYSEPSESATSVPPSDTPSLTSSVSSVC 2192
Query: 268 TIGPGND----QSATEVKIEKLPSIN---DLDSIFGPVLSPKSVAVNAEEKWVHFSDTSP 320
T + S T V E + I D + I P S+ EE V T+P
Sbjct: 2193 TTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAP 2252
Query: 321 EHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQ 380
+ V+S + +S P P GP T ++ + E
Sbjct: 2253 PD--GRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGN 2310
Query: 381 KKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPP-----------PTYRTVVSSPG-- 427
+ E D E + L + PP TY T + G
Sbjct: 2311 GIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQE 2370
Query: 428 -PGSGPGPGTTSGASSPARP------------ATPLVPCRSTTPPPPPPRPPSRPKLPPG 474
P S G+ S +S PA+P A P P PPPPPP PP P LPP
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP- 2429
Query: 475 KPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATT 520
P SP P I P + S +++ L A T
Sbjct: 2430 ---------PTSP------KPTILPKKKLTVASPVTTATPLFDAVT 2460
Score = 40.0 bits (92), Expect = 0.009
Identities = 80/389 (20%), Positives = 123/389 (31%), Gaps = 86/389 (22%)
Query: 155 KSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALA-PLFGPPLESAFDEQK 213
K P + PG+ K A+P P S KPP A P P + Q+
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPSQQPGSAKPSAQQPSPAKPSAQQ 553
Query: 214 TEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGN 273
+ + Q GSG+P+ P SP + PP G P TI P
Sbjct: 554 STKPVSQT---GSGKPLQPPTVSPSAKQ------------------PPSQGLPKTICPLC 592
Query: 274 DQSATEVKIEKLPSINDLDSIFGPVLS-------------PKSVAVNAEEKWVHFSDTSP 320
+ + + + + + N V S + + +N + K D +P
Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652
Query: 321 EHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQ 380
P +P+ K+ + P T + +P P
Sbjct: 653 ---VPS-SPQPKLKTAPVTTTSAVSKSSPQP----------------------------- 679
Query: 381 KKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGA 440
+QT K D ++PK L + P PPP + + P
Sbjct: 680 ----QQTSPKKD-----AAPKQ-DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL 729
Query: 441 SSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPL 500
S PA P P VP P +P + P V S P I SS +
Sbjct: 730 SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK---VQSQ 786
Query: 501 ARAESTSSISSTNSL-SAATTPTVENEQP 528
A ++T + + ++ S + PT E P
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815
Score = 34.7 bits (78), Expect = 0.37
Identities = 81/363 (22%), Positives = 124/363 (34%), Gaps = 92/363 (25%)
Query: 152 PVRKSPRRSPGAIKRNL-----SSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLE 206
PV+K+ + + I + +E+ R + E + PP AL P++
Sbjct: 2300 PVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIAL------PMK 2353
Query: 207 SAFDEQKTEVLLDQPEIWGSGQPIN------PSMES-PKLTRPF---------------- 243
EQ + E +G +P + PS+ S P RPF
Sbjct: 2354 ----EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP 2409
Query: 244 ---PTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLS 300
P PPP PP P PP + P TI P + K+ + +F V +
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKP-TILP-------KKKLTVASPVTTATPLFDAVTT 2461
Query: 301 PKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPL-GPPGPTG 359
++ AV S+ P R +PP P P+ P+ P P+
Sbjct: 2462 LETTAVLR-------SNGLP-------VTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSK 2507
Query: 360 PPGPPGP--PRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPP-- 415
PP P P P+ + ++ K + L ++S D+ L +P P
Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTS-ADYKLPSPTSPLSPHSN 2566
Query: 416 ----------PPTYRTVVSSPGPGSGPGPGTTSGAS---------SPARPATPLVPCRST 456
TY V++ P S PG T S AS SP++ + P S
Sbjct: 2567 KSSPRFSKSLTETY-VVITLP---SEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSV 2622
Query: 457 TPP 459
PP
Sbjct: 2623 VPP 2625
Score = 30.0 bits (66), Expect = 9.2
Identities = 43/204 (21%), Positives = 75/204 (36%), Gaps = 29/204 (14%)
Query: 53 GKKVSKKSNGAPNGFYAEIDWERYNSPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEE 112
GK+ K G P+G + E + + +E +P+ P + K E E+E+
Sbjct: 1288 GKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKE----QPQPPCTAKPDQVEPGKEKTEKED 1343
Query: 113 SHKKFNIKIKPLQSKDILKNAATVDELKASIGNI-ALSPSPVR--------------KSP 157
+ +P + + + D + +S+G I +L P+ + SP
Sbjct: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 158 RRSPGAIKRNLSSEEVARPRRSTPTPELISKK-PPDDTTALAPLFGPPLESAFDEQKTEV 216
K + + + ST E KK P + + E D++KT+
Sbjct: 1404 SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSP---------EQPKDQEKTQS 1454
Query: 217 LLDQPEIWGSGQPINPSMESPKLT 240
L + EI S + I S E K T
Sbjct: 1455 LSETLEITISEEEIKESQEERKDT 1478
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 84.3 bits (207), Expect = 4e-16
Identities = 113/485 (23%), Positives = 167/485 (34%), Gaps = 93/485 (19%)
Query: 103 SSSESEEEEESHKKFNIKIKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPG 162
S SE+ +EE + K+ ++ + + + I+K K P P ++ P R P
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK---------PIPKQQGPGRDP- 229
Query: 163 AIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPE 222
+ TP+ IS + P+ + P G P++ +T D +
Sbjct: 230 --------------LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQT----DHAK 271
Query: 223 IWGSGQPINPSMESPKLTRPFPTGTPPPLP-PKNVPATPPRTGSPLTIGPGNDQSATEVK 281
+ P + + R P LP P P P G P PG+++S
Sbjct: 272 LPLQRDASRPQTKQADIVRG--ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP--- 326
Query: 282 IEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPD 341
GP P P +T L + V PP P
Sbjct: 327 --------------GPAKPP----------------AQPSGLTKPLAQQPGTVKPPVQPP 356
Query: 342 NPADSPAPGPLGPPGP----TGPPGP----PGPPRNVLSPLNLEEVQKKVAEQTFIKDDY 393
PA PLGP P TG P PGP P V K A+Q
Sbjct: 357 GTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGPKALAQPP----GVGKTPAQQPGPAKPP 411
Query: 394 LETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGP----GPGTTSG-ASSPARPAT 448
+ + +PK P P +T V PGPG P GPG TS + P +P
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-- 469
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSS 508
P + P PPP+ P K PP +PG ++P S S+ PPP P S
Sbjct: 470 ---PSQLPGPAKPPPQQPGPAKPPPQQPG---SAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523
Query: 509 ISSTNSLS---AATTPTVENEQPSLVWFDRGKFYLTFEGSSRGPSPLTMGAQDTLPVAAA 565
ST S + P+ + P+ + ++ GS + P T+ P +
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQG 583
Query: 566 FTETV 570
+T+
Sbjct: 584 LPKTI 588
Score = 50.4 bits (119), Expect = 7e-06
Identities = 83/385 (21%), Positives = 131/385 (34%), Gaps = 56/385 (14%)
Query: 149 SPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTP---------TPELISKKPPDDTTALAP 199
SP P + SP++ A K++LS + P++ P +P +K+PP+ + P
Sbjct: 676 SPQPQQTSPKKD-AAPKQDLS--KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 200 LFGPPLESAF--DEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVP 257
PP E + ++ K V D+P+ +P + S T T P +P V
Sbjct: 733 --APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT------TKPDIPSSKVQ 784
Query: 258 A-TPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFS 316
+ +T PL + EK+ D +I P K ++ H
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-DSKAIPRPASDSKIIS--------HPG 835
Query: 317 DTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNL 376
+S ++ P +K P +P P P P G P PPGP +
Sbjct: 836 PSSESKGQKQVDPVQK----KEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGT 436
+ K EQ S LG P P T + V+ G G +
Sbjct: 892 PQQSPKPQEQ-----------SRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFS 940
Query: 437 -------TSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPI 489
T+G P + P P + P PP PK P S P
Sbjct: 941 QASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET 1000
Query: 490 HSSSPPPIAPLARAESTSSISSTNS 514
+ + + P +AE ++ T +
Sbjct: 1001 KAPAAEKLEP--KAEQAPTVKRTET 1023
Score = 47.0 bits (110), Expect = 7e-05
Identities = 60/223 (26%), Positives = 77/223 (34%), Gaps = 33/223 (14%)
Query: 315 FSDTSPEHVTPELTPREKVVSPPATP---------DNPADSPAPGPLGPPGPTGPPGPPG 365
F P P +P V S PA P D A P P P PP P PP PP
Sbjct: 2367 FGQEKPASQLPSGSP--SVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Query: 366 P-------PRNVLSPLNLEEVQKKVAEQTFIKD--DYLETISSPKDFGLGQR---ATPPP 413
P P+ + P V V T + D LET + + GL T PP
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484
Query: 414 PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPP 473
P PP ++ S P P S P P++P TT P P P
Sbjct: 2485 PVPPKPSSIPSGLVFTHRPEP------SKPPIAPKPVIPQLPTTTQKPTDIHPK----PT 2534
Query: 474 GKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLS 516
G ++ P P +PL+ + SS + SL+
Sbjct: 2535 GLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT 2577
Score = 45.8 bits (107), Expect = 2e-04
Identities = 94/406 (23%), Positives = 135/406 (33%), Gaps = 67/406 (16%)
Query: 156 SPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPL--------ES 207
SP ++P S+ + R ++ T ++S D+T+ A L P + E
Sbjct: 2081 SPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEE 2140
Query: 208 AFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPL 267
DE T+ + EI ES LT P+ + +PP + P+ S
Sbjct: 2141 IEDEYVTDYTREIQEIIAH--------ESLILTYSEPSESATSVPPSDTPSLTSSVSSVC 2192
Query: 268 TIGPGND----QSATEVKIEKLPSIN---DLDSIFGPVLSPKSVAVNAEEKWVHFSDTSP 320
T + S T V E + I D + I P S+ EE V T+P
Sbjct: 2193 TTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAP 2252
Query: 321 EHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQ 380
+ V+S + +S P P GP T ++ + E
Sbjct: 2253 PD--GRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGN 2310
Query: 381 KKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPP-----------PTYRTVVSSPG-- 427
+ E D E + L + PP TY T + G
Sbjct: 2311 GIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQE 2370
Query: 428 -PGSGPGPGTTSGASSPARP------------ATPLVPCRSTTPPPPPPRPPSRPKLPPG 474
P S G+ S +S PA+P A P P PPPPPP PP P LPP
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP- 2429
Query: 475 KPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATT 520
P SP P I P + S +++ L A T
Sbjct: 2430 ---------PTSP------KPTILPKKKLTVASPVTTATPLFDAVT 2460
Score = 40.0 bits (92), Expect = 0.009
Identities = 80/389 (20%), Positives = 123/389 (31%), Gaps = 86/389 (22%)
Query: 155 KSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALA-PLFGPPLESAFDEQK 213
K P + PG+ K A+P P S KPP A P P + Q+
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPSQQPGSAKPSAQQPSPAKPSAQQ 553
Query: 214 TEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGN 273
+ + Q GSG+P+ P SP + PP G P TI P
Sbjct: 554 STKPVSQT---GSGKPLQPPTVSPSAKQ------------------PPSQGLPKTICPLC 592
Query: 274 DQSATEVKIEKLPSINDLDSIFGPVLS-------------PKSVAVNAEEKWVHFSDTSP 320
+ + + + + + N V S + + +N + K D +P
Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652
Query: 321 EHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQ 380
P +P+ K+ + P T + +P P
Sbjct: 653 ---VPS-SPQPKLKTAPVTTTSAVSKSSPQP----------------------------- 679
Query: 381 KKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGA 440
+QT K D ++PK L + P PPP + + P
Sbjct: 680 ----QQTSPKKD-----AAPKQ-DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL 729
Query: 441 SSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPL 500
S PA P P VP P +P + P V S P I SS +
Sbjct: 730 SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK---VQSQ 786
Query: 501 ARAESTSSISSTNSL-SAATTPTVENEQP 528
A ++T + + ++ S + PT E P
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815
Score = 34.7 bits (78), Expect = 0.37
Identities = 81/363 (22%), Positives = 124/363 (34%), Gaps = 92/363 (25%)
Query: 152 PVRKSPRRSPGAIKRNL-----SSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLE 206
PV+K+ + + I + +E+ R + E + PP AL P++
Sbjct: 2300 PVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIAL------PMK 2353
Query: 207 SAFDEQKTEVLLDQPEIWGSGQPIN------PSMES-PKLTRPF---------------- 243
EQ + E +G +P + PS+ S P RPF
Sbjct: 2354 ----EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP 2409
Query: 244 ---PTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLS 300
P PPP PP P PP + P TI P + K+ + +F V +
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKP-TILP-------KKKLTVASPVTTATPLFDAVTT 2461
Query: 301 PKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPL-GPPGPTG 359
++ AV S+ P R +PP P P+ P+ P P+
Sbjct: 2462 LETTAVLR-------SNGLP-------VTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSK 2507
Query: 360 PPGPPGP--PRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPP-- 415
PP P P P+ + ++ K + L ++S D+ L +P P
Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTS-ADYKLPSPTSPLSPHSN 2566
Query: 416 ----------PPTYRTVVSSPGPGSGPGPGTTSGAS---------SPARPATPLVPCRST 456
TY V++ P S PG T S AS SP++ + P S
Sbjct: 2567 KSSPRFSKSLTETY-VVITLP---SEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSV 2622
Query: 457 TPP 459
PP
Sbjct: 2623 VPP 2625
Score = 30.0 bits (66), Expect = 9.2
Identities = 43/204 (21%), Positives = 75/204 (36%), Gaps = 29/204 (14%)
Query: 53 GKKVSKKSNGAPNGFYAEIDWERYNSPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEE 112
GK+ K G P+G + E + + +E +P+ P + K E E+E+
Sbjct: 1288 GKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKE----QPQPPCTAKPDQVEPGKEKTEKED 1343
Query: 113 SHKKFNIKIKPLQSKDILKNAATVDELKASIGNI-ALSPSPVR--------------KSP 157
+ +P + + + D + +S+G I +L P+ + SP
Sbjct: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 158 RRSPGAIKRNLSSEEVARPRRSTPTPELISKK-PPDDTTALAPLFGPPLESAFDEQKTEV 216
K + + + ST E KK P + + E D++KT+
Sbjct: 1404 SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSP---------EQPKDQEKTQS 1454
Query: 217 LLDQPEIWGSGQPINPSMESPKLT 240
L + EI S + I S E K T
Sbjct: 1455 LSETLEITISEEEIKESQEERKDT 1478
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 84.0 bits (206), Expect = 5e-16
Identities = 115/440 (26%), Positives = 151/440 (34%), Gaps = 56/440 (12%)
Query: 130 LKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTP---ELI 186
L + T+ L+A + SP S P + +L+ + P S TP L
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539
Query: 187 SKKPPDDTTALAPLFGPPLESAFD------EQKTEVLLDQPEIWGSGQPINPSMESPKLT 240
S PP TA APL P LE+ + L P S P P L
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 241 RP----------FPTGTPPP-------LPPKNVPATPPRTG--SPLTIGPGNDQSATEVK 281
P P TPPP LPP P +PP + SPL +A V
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 282 IEKLP-SINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELT--PREKVVSPPA 338
+ + P S + P P S V+ S T P P L P + SPPA
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSP-------SATPPSQAPPSLAAPPLQVPPSPPA 712
Query: 339 TPD-NPADSP---APGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYL 394
+P +P+ +P AP PL P PP PP P P++
Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-----PMSPSATPPPRVPPLLAAPPLQ 767
Query: 395 ETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCR 454
S P + A PPP PP T P + P P + +P P+ L
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALAT----PPLQALPSPPASFPGQAPFSPSASLPMSP 823
Query: 455 STTPPPPPPRPPSRPKL-----PPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSI 509
TPPP P + P L PP P + RP +P +S P LA A
Sbjct: 824 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 883
Query: 510 SSTNSLSAATTPTVENEQPS 529
S + S + P + S
Sbjct: 884 PSRSPSSTLSGPDLAGHSSS 903
Score = 71.2 bits (173), Expect = 4e-12
Identities = 116/523 (22%), Positives = 176/523 (33%), Gaps = 108/523 (20%)
Query: 87 SIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSKDILKNAA-TVDELKASIGN 145
S RP P K S+SE E S + +P + + A+ ++ + +
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAA---RRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 146 IALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPL 205
A S R +PR + + RP + TP + D AL PL PL
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPALGPLSSSPL 304
Query: 206 ESAFDEQKTEVLLDQPEIWGSGQPINPSME-SPKLTRPFPTGTPPPLPPKNV------PA 258
+ + P+ + P+ ++ SP L P P P P P ++ PA
Sbjct: 305 ATPSPSGTKARPVPPPD--NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 259 TPPRTGSPLTIGPGND--------------QSATEVKIEKLPS------INDLDSIFGPV 298
TPP P P S T ++ PS + S+ P
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 299 LSPKSVAVNAEEKWVHFSDTSPEH---VTPELTPREKVVSPPATPD-----NPADSPAPG 350
L + + S TSP P+ P + +S PA+P +PA SP
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 351 PLG------------------------PPGPT----GPPGPPGPPRNVLSPL--NLEEVQ 380
PL PP T PP PP ++ +P NL +
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Query: 381 KKVAEQTF--IKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTS 438
+ + +LET P L +P PPP + +++P P + P +
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 439 GASSPARPATPLVPCRSTTPPPPPPR----PPSRPKLPPGKPGVGDV------------- 481
P+ P +PL +T PP PP P P PP P + +
Sbjct: 603 LQGLPSPPLSPL----ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 658
Query: 482 -------SRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSA 517
S P SPP+ + PP +P +T + SL+A
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701
Score = 70.1 bits (170), Expect = 8e-12
Identities = 102/397 (25%), Positives = 138/397 (34%), Gaps = 81/397 (20%)
Query: 150 PSPVRKSPRRSPGAIKRNLSSEEVAR---PRRSTPTPEL--ISKKPPD--DTTALAPLFG 202
PSP+ P +P +I A P + P+P L ++ PP AL PL
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632
Query: 203 PPLESAFDEQKTEVLLDQPEIWGSGQPI-NPSMESPK------LTRPFPTGTPPPLPPKN 255
PP A P + P+ PS ++P L PF +PPP PP
Sbjct: 633 PPSPPA-----------SPPL----SPLATPSPQAPNALAVHLLQAPF---SPPPSPPVQ 674
Query: 256 VPATPPRTG--SPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVA---VNAEE 310
P +PP + SP P + ++P P +P A + A
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 311 KWVHFSDTSPEHVTPELTPREKV----VSPPA-TPDNPADSPAPGPLGPPGPTGPPGPPG 365
V S + ++P TP +V +PP P +P S PL P P PP
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 366 PPRNVL-SPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVS 424
PP L SP Q S + ATPPP PP V++
Sbjct: 795 PPLQALPSPPASFPGQ--------------APFSPSASLPMSPLATPPPQAPP----VLA 836
Query: 425 SPGPGSGPGPGTTSGASSPARPATP----------LVPCRSTTPPPPPPRPPSRPKLPPG 474
+P P P + +P RP TP L + PPPPP R PS P
Sbjct: 837 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 896
Query: 475 KPGVGDVSRPFSPPIH----------SSSPPPIAPLA 501
G + + ++SPPP A LA
Sbjct: 897 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 933
Score = 66.6 bits (161), Expect = 9e-11
Identities = 103/416 (24%), Positives = 138/416 (33%), Gaps = 87/416 (20%)
Query: 138 ELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSE-------EVARPRRSTPTPELISKKP 190
E IG + S R P RS G RN +S E A P ++T + S
Sbjct: 60 ERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
Query: 191 PDDTTALAPLFGPPLESAFDEQ----------KTEVLLDQPEIWGSGQ-PINPSMESPKL 239
TT PL L + +E K L SG P PS +
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 240 TRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVL 299
+R T P P + PP G ++ ++ S TE P+ S G +
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS----PAARRRPSAGGGLQ 235
Query: 300 SPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLG-----P 354
P S ++++ TP +P S TP PA P P G P
Sbjct: 236 RPASRSLSSS-------------ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 355 PGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPP- 413
P T P P L PL+ +++P G R PPP
Sbjct: 283 PQVTPPRKDAAP---ALGPLSSSP------------------LATPSPSGTKARPVPPPD 321
Query: 414 ----------PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPP 463
PP P T + P P + S PA P + P +T PP
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT---PPMQ 378
Query: 464 RPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAAT 519
PPS +PP + P S S PP +PLA SS+ +T SL + T
Sbjct: 379 APPSLQTIPP-------IQVPHSLTSPSLQAPP-SPLA----LSSLQATTSLGSPT 422
Score = 53.5 bits (127), Expect = 8e-07
Identities = 92/392 (23%), Positives = 132/392 (33%), Gaps = 106/392 (27%)
Query: 232 PSMESPKLTRPFPTGTPPPLPP-----------------------------KNVPATPPR 262
P+ +P L P P G+P P PP +P + PR
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 263 TGSPLTIGPGNDQSATEV----KIEKLPSINDLDSIFGPVLSP--------------KSV 304
G + G + A+ + E+ P + GPV SP K +
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP--GPVSSPGRASGTTRPGPLGQKGL 134
Query: 305 AVNAEEKWVHFSDT-SPEHVTPELTPREKVVSP-PATPDNPA---DSPAPGP---LGPPG 356
++AEE T +P+ R P P TP +PA S A G L P
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPA 193
Query: 357 PTGPPGPP--GPPRNVLSPLNLEEVQKKVAEQ-------------TFIKDDYLETISSPK 401
P+ P PP GP ++V S + A + + +SSP
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 402 DFGLGQRATP------------------PPPPPPTYRTVVSSPGPGSGPGPGTTSGASSP 443
G R TP PP P + + GP S T S + +
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313
Query: 444 ARPATP----LVPCRSTTPPPPP-----PRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSP 494
ARP P P +T PP PP P P P PP + S P +PP S +P
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL--PSPPATPP--SQAP 369
Query: 495 PPIA--PLARAESTSSISSTNSLSAATTPTVE 524
P + P+ S +I + T+P+++
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401
Score = 49.3 bits (116), Expect = 1e-05
Identities = 62/246 (25%), Positives = 86/246 (34%), Gaps = 42/246 (17%)
Query: 146 IALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTP---TPELISKKPPDDTTALAPLFG 202
+A P V SP SP S P R P P L P + ++PL
Sbjct: 730 LAAPPLQVPPSPPASPPM------SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783
Query: 203 PPLES--AFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPK------ 254
PP ++ A + L P + P +PS P P TPPP P
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS----PLATPPPQAPPVLAAPL 839
Query: 255 -NVPATPPRTGS------PLTIGPGNDQSATEVKIEKLP------SINDLDSIFGPVLSP 301
VP +PP + + P T GP S + + P S + ++ GP L+
Sbjct: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
Query: 302 KSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPP 361
S + + + + D+ PE SPP + A PA GP P
Sbjct: 900 HSSSATSTPEELRGYDSGPEGGA--------AASPPPDAELAACHPAAWSRGPAPPLAFR 951
Query: 362 GPPGPP 367
G PG P
Sbjct: 952 GAPGAP 957
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 82.0 bits (201), Expect = 2e-15
Identities = 128/551 (23%), Positives = 183/551 (33%), Gaps = 81/551 (14%)
Query: 36 SPHEPPYNSKA---ECAREGGKKVSKKSNGAPNG------FYAEIDWERYNSPELDEEGY 86
+P PP + KA A + K +K+S PN +E E ++ E E
Sbjct: 68 NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127
Query: 87 SIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIKI--------KPLQSKDILKNAA---- 134
S ST K SS S E KK +K KP ++ A
Sbjct: 128 SSSSSSSSSTIRK-IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLD 186
Query: 135 -------TVDELKASIGNIALSPS-----PVRKSPRRSPGA-----IKRNLSSEEVARPR 177
T D ++ SP P+ P P + ++ E +
Sbjct: 187 NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 246
Query: 178 RSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESP 237
+T T + S + TT+ SA D T +L +P P++ +P
Sbjct: 247 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 306
Query: 238 KLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGP 297
K P P PK +T P+ +P TI +SA E P+
Sbjct: 307 K--------EPTPTTPKEPASTTPKEPTPTTI-----KSAPTTPKEPAPTTTK-----SA 348
Query: 298 VLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADS----PAPGPLG 353
+PK A ++ + P T + S P TP PA + PAP
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 354 PPGPTGPPGP-------PGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLG 406
P PT P P P P +P +E ++ ++PK+
Sbjct: 409 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 468
Query: 407 QRATPPPPPP--PTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPR 464
P P P P T S+P P P TT A P TP P +TT P P
Sbjct: 469 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-----PTTPKEPSPTTTKEPAPTT 523
Query: 465 P----PSRPKLP-PGKPGVGDVSRPFSP-PIHSSSPPPIAPLARAESTSSISSTNSLSAA 518
P P+ PK P P P + P P P + P P P A +T ++ +
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583
Query: 519 TTPTVENEQPS 529
T T E P+
Sbjct: 584 TPTTPEKLAPT 594
Score = 72.8 bits (177), Expect = 1e-12
Identities = 100/414 (24%), Positives = 130/414 (31%), Gaps = 69/414 (16%)
Query: 150 PSPVR-KSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESA 208
PSP K P + + E +S PT + K P TT P P E A
Sbjct: 473 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT----TPKEPSPTTTKEPAPTTPKEPA 528
Query: 209 FDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT 268
K P P+ +PK P T P P PK T P+ +P T
Sbjct: 529 PTTPKKPA---------PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579
Query: 269 IGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELT 328
+ T EKL P K EE + T+PE TP
Sbjct: 580 -----PKKLTPTTPEKL----------APTTPEKPAPTTPEE----LAPTTPEEPTPTTP 620
Query: 329 PREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGP-PGPPRNV-------LSPLNLEEVQ 380
+P A N PAP P PT P P P P+ +P L+E
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 680
Query: 381 KKVAEQTFIKDDYLETISSPKDFGLGQRA----------TPPPPPPPTYRTVVSSPGPGS 430
++ K+ T P + A TP P P T + + G+
Sbjct: 681 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 740
Query: 431 GPGPGTTSGASSPARPA-------TPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSR 483
P ++P +PA T P +T+ P P P P +P +
Sbjct: 741 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 800
Query: 484 PFSPPIHSSSPPPI-----APLARAEST----SSISSTNSLSAATTPTVENEQP 528
P P +PPP P E T S ST LSA TP P
Sbjct: 801 P--APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 852
Score = 56.2 bits (134), Expect = 1e-07
Identities = 87/365 (23%), Positives = 133/365 (36%), Gaps = 59/365 (16%)
Query: 176 PRRSTPT-PELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQP-----EIWGSGQP 229
P++ TPT PE ++ P+ AP L E+ T ++P + P
Sbjct: 580 PKKLTPTTPEKLAPTTPEKP---APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 636
Query: 230 INPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSIN 289
P+ +PK P P P PK T P+ +P T+ + + T K P+
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL---KEPAPTT---PKKPAPK 690
Query: 290 DLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSP-- 347
+L P + + + ++ + T+P+ P TP+E P TP PA +
Sbjct: 691 EL----APTTTKEPTSTTCDKP----APTTPKGTAPT-TPKEPA---PTTPKEPAPTTPK 738
Query: 348 --APGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGL 405
AP L P PT P P +P L K T D T +PK+
Sbjct: 739 GTAPTTLKEPAPTTPKKP--------APKELAPTTTKGPTST-TSDKPAPT--TPKETA- 786
Query: 406 GQRATPPPPPPPTYRTVVSSPGPGS-GPGPGTTSGASSPARPATPLVPCRS---TTPPPP 461
TP P P T P P + P TTS S+P P +S +TP
Sbjct: 787 --PTTPKEPAP----TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 840
Query: 462 PPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTP 521
P + P +PGV P +++ P + A+ ++T T + P
Sbjct: 841 AEPTPKALENSPKEPGVPTTKTP------AATKPEMTTTAKDKTTERDLRTTPETTTAAP 894
Query: 522 TVENE 526
+ E
Sbjct: 895 KMTKE 899
Score = 50.4 bits (119), Expect = 7e-06
Identities = 91/403 (22%), Positives = 130/403 (32%), Gaps = 36/403 (8%)
Query: 78 SPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIK-IKPLQSKDILKNAATV 136
+P +E P+E T K ++ E + KK K + P +K+
Sbjct: 648 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707
Query: 137 DELKASIGNIALSPS-PVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTT 195
G +P P +P+ + + + P +TP KKP
Sbjct: 708 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP------KKPAPKEL 761
Query: 196 ALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKN 255
A GP ++ T P+ P P+ +PK +P PT P P +
Sbjct: 762 APTTTKGPTSTTSDKPAPTT-----PKETAPTTPKEPAPTTPK--KPAPTTPETPPPTTS 814
Query: 256 VPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHF 315
+TP T P TI D+S E+ E P + V + K+ A E
Sbjct: 815 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 874
Query: 316 SD--------TSPEHVT--PELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPG 365
D T+PE T P++T + T + T P
Sbjct: 875 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 934
Query: 366 PPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSS 425
L+P KK T I + ET + PKD +AT P P PT +
Sbjct: 935 LKTTTLAPK--VTTTKKTITTTEIMNKPEET-AKPKDRATNSKATTPKPQKPT----KAP 987
Query: 426 PGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSR 468
P S P T P TP R T P P SR
Sbjct: 988 KKPTSTKKPKTMPRVRKPKTTPTP----RKMTSTMPELNPTSR 1026
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 82.0 bits (201), Expect = 2e-15
Identities = 128/551 (23%), Positives = 183/551 (33%), Gaps = 81/551 (14%)
Query: 36 SPHEPPYNSKA---ECAREGGKKVSKKSNGAPNG------FYAEIDWERYNSPELDEEGY 86
+P PP + KA A + K +K+S PN +E E ++ E E
Sbjct: 109 NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168
Query: 87 SIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIKI--------KPLQSKDILKNAA---- 134
S ST K SS S E KK +K KP ++ A
Sbjct: 169 SSSSSSSSSTIRK-IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLD 227
Query: 135 -------TVDELKASIGNIALSPS-----PVRKSPRRSPGA-----IKRNLSSEEVARPR 177
T D ++ SP P+ P P + ++ E +
Sbjct: 228 NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 287
Query: 178 RSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESP 237
+T T + S + TT+ SA D T +L +P P++ +P
Sbjct: 288 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 347
Query: 238 KLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGP 297
K P P PK +T P+ +P TI +SA E P+
Sbjct: 348 K--------EPTPTTPKEPASTTPKEPTPTTI-----KSAPTTPKEPAPTTTK-----SA 389
Query: 298 VLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADS----PAPGPLG 353
+PK A ++ + P T + S P TP PA + PAP
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 354 PPGPTGPPGP-------PGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLG 406
P PT P P P P +P +E ++ ++PK+
Sbjct: 450 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 509
Query: 407 QRATPPPPPP--PTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPR 464
P P P P T S+P P P TT A P TP P +TT P P
Sbjct: 510 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-----PTTPKEPSPTTTKEPAPTT 564
Query: 465 P----PSRPKLP-PGKPGVGDVSRPFSP-PIHSSSPPPIAPLARAESTSSISSTNSLSAA 518
P P+ PK P P P + P P P + P P P A +T ++ +
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624
Query: 519 TTPTVENEQPS 529
T T E P+
Sbjct: 625 TPTTPEKLAPT 635
Score = 72.8 bits (177), Expect = 1e-12
Identities = 100/414 (24%), Positives = 130/414 (31%), Gaps = 69/414 (16%)
Query: 150 PSPVR-KSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESA 208
PSP K P + + E +S PT + K P TT P P E A
Sbjct: 514 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT----TPKEPSPTTTKEPAPTTPKEPA 569
Query: 209 FDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT 268
K P P+ +PK P T P P PK T P+ +P T
Sbjct: 570 PTTPKKPA---------PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 620
Query: 269 IGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELT 328
+ T EKL P K EE + T+PE TP
Sbjct: 621 -----PKKLTPTTPEKL----------APTTPEKPAPTTPEE----LAPTTPEEPTPTTP 661
Query: 329 PREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGP-PGPPRNV-------LSPLNLEEVQ 380
+P A N PAP P PT P P P P+ +P L+E
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 721
Query: 381 KKVAEQTFIKDDYLETISSPKDFGLGQRA----------TPPPPPPPTYRTVVSSPGPGS 430
++ K+ T P + A TP P P T + + G+
Sbjct: 722 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 781
Query: 431 GPGPGTTSGASSPARPA-------TPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSR 483
P ++P +PA T P +T+ P P P P +P +
Sbjct: 782 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 841
Query: 484 PFSPPIHSSSPPPI-----APLARAEST----SSISSTNSLSAATTPTVENEQP 528
P P +PPP P E T S ST LSA TP P
Sbjct: 842 P--APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 893
Score = 56.2 bits (134), Expect = 1e-07
Identities = 87/365 (23%), Positives = 133/365 (36%), Gaps = 59/365 (16%)
Query: 176 PRRSTPT-PELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQP-----EIWGSGQP 229
P++ TPT PE ++ P+ AP L E+ T ++P + P
Sbjct: 621 PKKLTPTTPEKLAPTTPEKP---APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 677
Query: 230 INPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSIN 289
P+ +PK P P P PK T P+ +P T+ + + T K P+
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL---KEPAPTT---PKKPAPK 731
Query: 290 DLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSP-- 347
+L P + + + ++ + T+P+ P TP+E P TP PA +
Sbjct: 732 EL----APTTTKEPTSTTCDKP----APTTPKGTAPT-TPKEPA---PTTPKEPAPTTPK 779
Query: 348 --APGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGL 405
AP L P PT P P +P L K T D T +PK+
Sbjct: 780 GTAPTTLKEPAPTTPKKP--------APKELAPTTTKGPTST-TSDKPAPT--TPKETA- 827
Query: 406 GQRATPPPPPPPTYRTVVSSPGPGS-GPGPGTTSGASSPARPATPLVPCRS---TTPPPP 461
TP P P T P P + P TTS S+P P +S +TP
Sbjct: 828 --PTTPKEPAP----TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 881
Query: 462 PPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTP 521
P + P +PGV P +++ P + A+ ++T T + P
Sbjct: 882 AEPTPKALENSPKEPGVPTTKTP------AATKPEMTTTAKDKTTERDLRTTPETTTAAP 935
Query: 522 TVENE 526
+ E
Sbjct: 936 KMTKE 940
Score = 50.4 bits (119), Expect = 7e-06
Identities = 91/403 (22%), Positives = 130/403 (32%), Gaps = 36/403 (8%)
Query: 78 SPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIK-IKPLQSKDILKNAATV 136
+P +E P+E T K ++ E + KK K + P +K+
Sbjct: 689 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 748
Query: 137 DELKASIGNIALSPS-PVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTT 195
G +P P +P+ + + + P +TP KKP
Sbjct: 749 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP------KKPAPKEL 802
Query: 196 ALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKN 255
A GP ++ T P+ P P+ +PK +P PT P P +
Sbjct: 803 APTTTKGPTSTTSDKPAPTT-----PKETAPTTPKEPAPTTPK--KPAPTTPETPPPTTS 855
Query: 256 VPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHF 315
+TP T P TI D+S E+ E P + V + K+ A E
Sbjct: 856 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 915
Query: 316 SD--------TSPEHVT--PELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPG 365
D T+PE T P++T + T + T P
Sbjct: 916 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 975
Query: 366 PPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSS 425
L+P KK T I + ET + PKD +AT P P PT +
Sbjct: 976 LKTTTLAPK--VTTTKKTITTTEIMNKPEET-AKPKDRATNSKATTPKPQKPT----KAP 1028
Query: 426 PGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSR 468
P S P T P TP R T P P SR
Sbjct: 1029 KKPTSTKKPKTMPRVRKPKTTPTP----RKMTSTMPELNPTSR 1067
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 80.9 bits (198), Expect = 5e-15
Identities = 109/446 (24%), Positives = 157/446 (35%), Gaps = 80/446 (17%)
Query: 122 KPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTP 181
KPL + AT+ E G S P R+P A +N S V+ P R++
Sbjct: 56 KPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPA--KNTSPGPVSSPGRASG 113
Query: 182 T--PELISKK----PPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSME 235
T P + +K ++T A P SA P PS
Sbjct: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT-------SGPTPGTPSPA 166
Query: 236 SPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIE-----------K 284
+ +R T P P + PP G ++ ++ S TE +
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226
Query: 285 LPSINDLDSIFGPVLSPKSVAVNAE---EKWVHFSDTSPEHV----TPELTPREKVVSPP 337
P+ L S P+ SP +A H S P+ + P++TP K +P
Sbjct: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 286
Query: 338 ATPDNPADSPAPGPLGPPGPTGPPG-------PPGPPRNVLSPLNLEEVQKKVAEQTFIK 390
P + + P P PP P+ PP P PP + L +Q A +F+
Sbjct: 287 LGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ---ATHSFLP 343
Query: 391 DDYLETISSPKDFGLGQRATPP---PPPPPTYRTV--VSSPGP---------------GS 430
L +++P A PP PP PP + +++P P
Sbjct: 344 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 403
Query: 431 GPGPGTTSGASSPARPATPLVPCRSTTPP---PP---------PPRPPSRPKLPPGKPGV 478
P P + S PA P P+ P S TPP PP PP PP+ P + P
Sbjct: 404 PPSPPVQAPFSPPASP--PVSP--SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459
Query: 479 GDVSRPF-SPPIHSSSPPPIAPLARA 503
P +PP+ + PPP AP A A
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALA 485
Score = 75.9 bits (185), Expect = 1e-13
Identities = 103/398 (25%), Positives = 134/398 (33%), Gaps = 87/398 (21%)
Query: 147 ALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLE 206
AL P V PR+ LSS +A P S P PP T +P PP +
Sbjct: 270 ALRPPQVTP-PRKDAAPALGPLSSSPLATPSPSAPPSP---SAPPSLQTLPSPPATPPSQ 325
Query: 207 SAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPP-------LPPKNVPAT 259
+ L P + Q + + SP L+ P TPPP LPP P +
Sbjct: 326 ATTS-------LGSPTL----QATHSFLPSPPLS---PLATPPPQAPPALALPPLQAPPS 371
Query: 260 PPRTG--SPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSD 317
PP + SPL +A V + + P F P SP A FS
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAP--------FSPPPSPPVQAP--------FSP 415
Query: 318 TSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPP-GPTGPPGPPGPPRNVLSPLNL 376
+ V+P TP + +PP+ P P P PP P+ P P PP PL L
Sbjct: 416 PASPPVSPSATPPSQ--APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGT 436
A PPP PP T P + P P
Sbjct: 474 --------------------------------AKPPPQAPPALAT----PPLQALPSPPA 497
Query: 437 TSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKL-----PPGKPGVGDVSRPFSPPIHS 491
+ +P P+ L TPPP P + P L PP P + RP +P +
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 557
Query: 492 SSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPS 529
S P LA A S + S + P + S
Sbjct: 558 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595
Score = 73.9 bits (180), Expect = 6e-13
Identities = 115/470 (24%), Positives = 154/470 (32%), Gaps = 85/470 (18%)
Query: 87 SIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSKDILKNAA-TVDELKASIGN 145
S RP P K S+SE E S + +P + + A+ ++ + +
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAA---RRRPSAGGGLQRPASRSLSSSATPLSS 242
Query: 146 IALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPL 205
A S R +PR + + RP + TP + D AL PL PL
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPALGPLSSSPL 295
Query: 206 ESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPP-----LPPKNVPAT- 259
+ P +PS T P P TPP L + AT
Sbjct: 296 ATP----------------SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 339
Query: 260 ---PPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFS 316
P SPL P A + + P P+ +P A NA + +
Sbjct: 340 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 399
Query: 317 DTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPG---------PP 367
SP P P SPP +P S AP L P PP PP PP
Sbjct: 400 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459
Query: 368 RNVLSPLNLEEVQ-KKVAEQT--FIKDDYLETISSPKDFGLGQR-------------ATP 411
PL +Q K Q + L+ + SP GQ ATP
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Query: 412 PPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATP----------LVPCRSTTPPPP 461
PP PP V+++P P P + +P RP TP L + PPPP
Sbjct: 520 PPQAPP----VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575
Query: 462 PPRPPSRPKLPPGKPGVGDVSRPFSPPIH----------SSSPPPIAPLA 501
P R PS P G + + ++SPPP A LA
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 625
Score = 50.8 bits (120), Expect = 5e-06
Identities = 63/242 (26%), Positives = 90/242 (37%), Gaps = 45/242 (18%)
Query: 145 NIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPP 204
++A P V SP SP + + + A P + P P ++K PP ALA PP
Sbjct: 434 SLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALAT---PP 488
Query: 205 LESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPK-------NVP 257
L++ L P + P +PS P P TPPP P VP
Sbjct: 489 LQA---------LPSPPASFPGQAPFSPSASLPMS----PLATPPPQAPPVLAAPLLQVP 535
Query: 258 ATPPRTGS------PLTIGPGNDQSATEVKIEKLP------SINDLDSIFGPVLSPKSVA 305
+PP + + P T GP S + + P S + ++ GP L+ S +
Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595
Query: 306 VNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPG 365
+ + + D+ PE SPP + A PA GP P G PG
Sbjct: 596 ATSTPEELRGYDSGPEGGA--------AASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 647
Query: 366 PP 367
P
Sbjct: 648 AP 649
Score = 47.0 bits (110), Expect = 7e-05
Identities = 87/367 (23%), Positives = 117/367 (31%), Gaps = 108/367 (29%)
Query: 232 PSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDL 291
P+ +P L P P G+P P PP PA G+ +G + P
Sbjct: 17 PAARAPGLLTPRPPGSPRP-PPPVTPAALRVLGAAGAVG-------------RKPLAERA 62
Query: 292 DSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPRE---KVVSPPATPDN----PA 344
I G + PE PR + PPA+ PA
Sbjct: 63 GGIGGATI-------------------------PESAPRAGPTRTSRPPASGRGERAPPA 97
Query: 345 DSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEV----------QKKVAEQTFIKDDYL 394
+ +PGP+ PG PGP ++ EE ++ +D
Sbjct: 98 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 157
Query: 395 ETISSPK------------DFGLGQRATPPPPPPPTY--RTVVSS--------PGPGSGP 432
T +P + GL + A P PPT R VSS P P +
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 433 GPGTTSGASSPA-----RPATPL-VPCRSTTPPPPPPRPPSRPKLPPGK----------- 475
P G PA ATPL P RS PR P+ P P K
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277
Query: 476 -------PGVGDV-SRPFSPPIHSSSPPPIAP-----LARAESTSSISSTNSLSAATTPT 522
P +G + S P + P S+ P P AP L +T +T SL + T
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337
Query: 523 VENEQPS 529
+ PS
Sbjct: 338 THSFLPS 344
Score = 30.4 bits (67), Expect = 7.0
Identities = 31/106 (29%), Positives = 41/106 (38%), Gaps = 22/106 (20%)
Query: 438 SGASSPARPATPLVPCRST-TPPPPPPRPPS------------RPKLPPGKPGVGDV--- 481
+ A +PA A L+ R +P PPPP P+ R L G+G
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 482 -SRPFSPPIHSSSPPPI-----APLARAESTSSISSTNSLSAATTP 521
S P + P +S PP AP A+ S +SS S T P
Sbjct: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 117
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 80.9 bits (198), Expect = 5e-15
Identities = 117/442 (26%), Positives = 167/442 (37%), Gaps = 44/442 (9%)
Query: 78 SPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSKDILKNAATVD 137
SP +E S PEE ++ +S S EES + P + +
Sbjct: 546 SPPFEESPLSPPPEELPTSPPPE--ASRLSPPPEES------PMSPPPEESPMSPPPEAS 597
Query: 138 ELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTAL 197
L LSP P +SP P R LS P +P PE PP + + L
Sbjct: 598 RLFPPFEESPLSPPP-EESPLSPPPEASR-LSPPPEDSPM--SPPPEESPMSPPPEVSRL 653
Query: 198 APLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVP 257
+PL P+ S E L P P +P E+ +L+ P P +P PP++ P
Sbjct: 654 SPL---PVVSRLSPPPEESPLSPPP---EESPTSPPPEASRLSPP-PEDSPTSPPPEDSP 706
Query: 258 ATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDL-DSIFGPVLSPKSVAVNAEEKWVHFS 316
A+PP S +++ E + LP L GP LSP+ + +
Sbjct: 707 ASPPPEDSLMSL------PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPR-PEEP 759
Query: 317 DTSPEHVTPELTPREKVVSPPATPDNPADSP-APGPLGPPGPTGPPGPPGPPRNVLSPLN 375
SP+ P L+P+ + A P+ P SP A GP P P P LSP+
Sbjct: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819
Query: 376 LEEVQKKVAEQTFIKDDYLETISSPK--DFGLGQRATPPPPPPPTYRTVVSSPGPGSGPG 433
E E++ + E SP+ + L PP P R PG P
Sbjct: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSP---RPEKPPEEPGQCPA 876
Query: 434 PGTTSGASSPARPA-TPLV--PCRSTTPPPP-PPRPPSRPKLPPGKPGVGD-------VS 482
P P P+ +PL+ P S PP P P P P G+P + +
Sbjct: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
Query: 483 RPFSPPIHSSSPPPIAPLARAE 504
P SP I +++PP ++PL E
Sbjct: 937 PPLSPIITAAAPPALSPLGELE 958
Score = 75.1 bits (183), Expect = 2e-13
Identities = 134/560 (23%), Positives = 188/560 (33%), Gaps = 140/560 (25%)
Query: 28 PDRDGIQPSPHEPPYNSKAE-------------CAREGGKKVSKKSNGAPNGFYAEIDWE 74
P+ + P P EP + +AE CA +S ++ G E E
Sbjct: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPE---E 803
Query: 75 RYNSPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSKDILKNAA 134
+ SP+ +E S PEEP S + EESH + P + L
Sbjct: 804 LHLSPQTEEPHLSPVPEEP-----------CLSPQPEESH------LSPQSEEPCLSPRP 846
Query: 135 TVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDT 194
L + LSP P + P PG P PE + PP
Sbjct: 847 EESHLSPELEKPPLSPRP--EKPPEEPG----------------QCPAPEELPLFPPPGE 888
Query: 195 TALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPK 254
+L+PL G P S E L ++ + SG+P SP+L P P PPPL P
Sbjct: 889 PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP----SLSPQLMPPDPL--PPPLSPI 942
Query: 255 NVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVH 314
A PP SPL G + K + P I +SP A
Sbjct: 943 ITAAAPPAL-SPL----GELEYPFGAKGDSDPESPLAAPILETPISPPPEA--------- 988
Query: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPP-------------GPTGPP 361
+ T PE V P + P P +P PA PL P P
Sbjct: 989 -NCTDPEPVPPMILPPS-----PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQC 1042
Query: 362 GPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPP----- 416
PP P +V SPL+ V+++ + + E +S P+ L AT P P P
Sbjct: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLS 1102
Query: 417 ---PTYRTVVSS--------------PGPGSGPGPGTTSGA------SSPA-------RP 446
P+ + PGS P PG T G+ SP P
Sbjct: 1103 CPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAP 1162
Query: 447 ATPL---VPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPP--IHSSSPPPIAPLA 501
TP+ C+ T P P+ P +PP I S I+ L+
Sbjct: 1163 VTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP----------TPPTLIKSDIVNEISNLS 1212
Query: 502 RAESTSSISSTNSLSAATTP 521
+ ++++S + L + P
Sbjct: 1213 QGDASASFPGSEPLLGSPDP 1232
Score = 70.5 bits (171), Expect = 6e-12
Identities = 90/353 (25%), Positives = 126/353 (35%), Gaps = 61/353 (17%)
Query: 148 LSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLES 207
LSP P P A+ + EE +P PE PP +++ +PL PL
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPL----SPPPEESPLSPPPESSPFSPLEESPLSP 522
Query: 208 AFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPL 267
+ + L P++P E+ L+ PF P PP+ +P +PP S L
Sbjct: 523 PEESPPSPAL---------ETPLSPPPEASPLSPPFEESPLSP-PPEELPTSPPPEASRL 572
Query: 268 TIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPEL 327
+ P + P SP S A + F + SP PE
Sbjct: 573 SPPPEESPMSPP-----------------PEESPMSPPPEASRLFPPFEE-SPLSPPPEE 614
Query: 328 TPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQT 387
+P +SPP + P P+ PP P PP P + LSPL + E++
Sbjct: 615 SP----LSPPPEASRLSPPPEDSPMSPPPEESPMSPP-PEVSRLSPLPVVSRLSPPPEES 669
Query: 388 FIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGP-GPGTTSGASSPARP 446
+ E+ +SP R +PPP PT SP P P P S
Sbjct: 670 PLSPPPEESPTSPPP--EASRLSPPPEDSPT------SPPPEDSPASPPPEDSLMSLPLE 721
Query: 447 ATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAP 499
+PL+P P P+L P G RP P + SP P P
Sbjct: 722 ESPLLPL------------PEEPQLCPRSEGPHLSPRPEEPHL---SPRPEEP 759
Score = 63.2 bits (152), Expect = 1e-09
Identities = 90/355 (25%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 176 PRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSME 235
P+ P E + PP + + L+P PP ES L P P +P E
Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLSP---PPEESPTSPPPEASRLSPPP---EELPASPLPE 481
Query: 236 SPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIF 295
+ L+RP P PP+ P +PP SP + +E+ P +S
Sbjct: 482 ALHLSRPLEESPLSP-PPEESPLSPPPESSPFS------------PLEESPLSPPEESPP 528
Query: 296 GPVL-SPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGP 354
P L +P S A F + SP PE P SPP + P P+ P
Sbjct: 529 SPALETPLSPPPEASPLSPPFEE-SPLSPPPEELP----TSPPPEASRLSPPPEESPMSP 583
Query: 355 PGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPP 414
P P PP + P + E +S P + R +PPP
Sbjct: 584 PPEESPMSPPPEASRLFPPFEESPLSPPPEESP---------LSPPPE---ASRLSPPPE 631
Query: 415 PPPTYRTVVSSPGPGSGP-GPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPP 473
P SP P P P SP + L P PP P P + P
Sbjct: 632 DSPM------SPPPEESPMSPPPEVSRLSPLPVVSRLSP-----PPEESPLSPPPEESPT 680
Query: 474 GKPGVGDVSRPFSPPIHS-SSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQ 527
P + SR PP S +SPPP A S+ S + P E Q
Sbjct: 681 SPP--PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ 733
Score = 55.5 bits (132), Expect = 2e-07
Identities = 98/382 (25%), Positives = 131/382 (34%), Gaps = 94/382 (24%)
Query: 183 PELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSM----ESPK 238
P++ ++ P D LAP + PLE F T P +G P P M P
Sbjct: 2165 PQVPAQVPSQDPFGLAPAY--PLEPRFP---TAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219
Query: 239 LTRPFPTGTPPPLPPKNVPATP-----PRTGS-------------------PLTIGP--G 272
+P T PP P++ P+TP PR S PL P G
Sbjct: 2220 AGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFG 2279
Query: 273 NDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDT---SPEHVTPELTP 329
+ A EVK E+L + + +GP P V++ H +P+ LTP
Sbjct: 2280 ESRKALEVKKEELGASSPS---YGP---PNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP 2333
Query: 330 REKVVSPPAT-----PDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVA 384
R V P + P P PP P PP P
Sbjct: 2334 RASQVEPQSPGLGLRPQEP----------PPAQALAPSPPSHP----------------- 2366
Query: 385 EQTFIKDDYLETISSPKDFGLGQRATPPPPP-----PPTYRTVVSSPGPGSGPGPGTTSG 439
F Y + + P L R PPPP PP R++ S P P + S
Sbjct: 2367 -DIFRPGSYTDPYAQPP---LTPRPQPPPPESCCALPP--RSLPSDPFSRVPASPQSQSS 2420
Query: 440 ASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAP 499
+ SP P +P P + P PP +P D PF+ P+H PP P
Sbjct: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRD---PFA-PLH--KPPRPQP 2474
Query: 500 LARAESTSSISSTNSLSAATTP 521
A S++ T SL A P
Sbjct: 2475 PEVAFKAGSLAHT-SLGAGGFP 2495
Score = 46.6 bits (109), Expect = 9e-05
Identities = 91/387 (23%), Positives = 128/387 (33%), Gaps = 96/387 (24%)
Query: 144 GNIALSPSPVRKSPRRSPGAIKRNLSSEE---VARPRRSTPTPELISKKPP-------DD 193
G +A+ +P +S PG +K +LS + + +P+ P P + +PP
Sbjct: 4047 GPLAIGTTP--ESMATEPGEVKPSLSGDSQLLLVQPQPQ-PQPSSLQLQPPLRLPGQQQQ 4103
Query: 194 TTALAPLFGP----PLESAFDEQKTEV--LLDQPEIWGSGQPINPSM-----ESPKLTRP 242
+L G L S + + V LL QP + QP + + + P L RP
Sbjct: 4104 QVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERP 4163
Query: 243 FPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPK 302
T P PP+ G L G G LP + + ++ G + +
Sbjct: 4164 MQNNTGPQ---------PPKPGPVLQSGQG------------LPGVGIMPTV-GQLRAQL 4201
Query: 303 SVAVNAEEKWVHFSDTSPEHVTPELTPREKVVS------PPATPDNPADSPAPGPLGPPG 356
+ + H S + + L R+ S PP SP G LG
Sbjct: 4202 QGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQP 4261
Query: 357 PTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPP--P 414
G G PGP L L G G R PP P
Sbjct: 4262 QLG--GFPGPQTGPLQEL-----------------------------GAGPRPQGPPRLP 4290
Query: 415 PPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPG 474
PP S GP GP T P++P P R + P P + P+ +LPP
Sbjct: 4291 APPG----ALSTGPVLGPVHPTPP-------PSSPQEPKRPSQLPSPSSQLPTEAQLPPT 4339
Query: 475 KPGVGDVSRPFSPPIHSSSPPPIAPLA 501
PG P P P A LA
Sbjct: 4340 HPGTPKPQGPTLEPPPGRVSPAAAQLA 4366
Score = 45.4 bits (106), Expect = 2e-04
Identities = 54/210 (25%), Positives = 73/210 (34%), Gaps = 18/210 (8%)
Query: 323 VTPELTPREKVVSPPATPDNPADSPAP-------GPLGPPGPTGPPGPPGPPRNVLSPLN 375
V + TP SPP D P D P P G + P PGP + PL
Sbjct: 361 VAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG 420
Query: 376 LEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPG 435
VQ + + + ++ + + P++ L +PPP PT S P S P
Sbjct: 421 KAGVQLEPQLEAPLNEE-MPLLPPPEESPL----SPPPEESPT-----SPPPEASRLSPP 470
Query: 436 TTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPP 495
+SP A L +P PPP P P P SPP S P
Sbjct: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530
Query: 496 PI-APLARAESTSSISSTNSLSAATTPTVE 524
+ PL+ S +S S + P E
Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEE 560
Score = 44.7 bits (104), Expect = 4e-04
Identities = 52/193 (26%), Positives = 69/193 (35%), Gaps = 19/193 (9%)
Query: 347 PAPGPLGPPGPTGPP----GPPGPPRNV-------LSPLNLEEVQKKVAEQTFIK--DDY 393
P PG LG P P P G P P + L P + F+K
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
Query: 394 LETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPC 453
+ S FGL P P T P P P GASS RP
Sbjct: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASS--RPGAGQPGE 2225
Query: 454 RSTTPPPPPPRPPSRPK--LPPGKPGVGDVSRPFSPPI--HSSSPPPIAPLARAESTSSI 509
TTPP P PS P L P P + +++ P SP + +S P ++P ES ++
Sbjct: 2226 FHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKAL 2285
Query: 510 SSTNSLSAATTPT 522
A++P+
Sbjct: 2286 EVKKEELGASSPS 2298
Score = 42.0 bits (97), Expect = 0.002
Identities = 66/299 (22%), Positives = 91/299 (30%), Gaps = 79/299 (26%)
Query: 182 TPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTR 241
TP +P L P PP ++ + P+I+ G +P + P R
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSH-----PDIFRPGSYTDPYAQPPLTPR 2386
Query: 242 PFPTGTPPP-----LPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFG 296
P P PPP LPP+++P+ P ++P+ S
Sbjct: 2387 PQP---PPPESCCALPPRSLPSDP---------------------FSRVPASPQSQSSSQ 2422
Query: 297 PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPG 356
L+P+ ++ A P VTP + PP+ P + P
Sbjct: 2423 SPLTPRPLSAEA---------FCPSPVTPRFQSPDPYSRPPSRPQSR---------DPFA 2464
Query: 357 PTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPP 416
P P P PP E F T F A P P
Sbjct: 2465 PLHKPPRPQPP-----------------EVAFKAGSLAHTSLGAGGF---PAALPAGPAG 2504
Query: 417 PTYRTVVSSPGPG--SGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPP 473
+ V S P PG G G SP R P + PP P +P LPP
Sbjct: 2505 ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP-----QPGLPP 2558
Score = 37.7 bits (86), Expect = 0.044
Identities = 81/375 (21%), Positives = 118/375 (31%), Gaps = 64/375 (17%)
Query: 151 SPVRKSPRRSPGAIKRNLSSEEVA----RPRRSTPTPELISKKPPDDTTALAPLFGPPLE 206
SP +S +SP R LS+E PR +P P P APL PP
Sbjct: 2414 SPQSQSSSQSP-LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP 2472
Query: 207 SAFDEQKTEVLLDQPEIWGSGQPIN-------------PSMESPKLTRPFPTG----TPP 249
+ L + G P PS + P R TG TP
Sbjct: 2473 QPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPS 2532
Query: 250 PL--------------PPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIF 295
P+ PP P PP G GPG + + + N F
Sbjct: 2533 PMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGN-----F 2587
Query: 296 GPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVV---------SPPATPDNPADS 346
P SP + + + S P V P P + S +P +
Sbjct: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647
Query: 347 PAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLG 406
P G PG P + LS LE+ +++ + + ++ + ++
Sbjct: 2648 PGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETA 2707
Query: 407 QRATPPPPPPPTYRTVVSSP-----GPGSGPGPGTTSGAS----SPARPATPLV-----P 452
A PP ++ SSP G P GT +S P++ + P++ P
Sbjct: 2708 AAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFP 2767
Query: 453 CRSTTPPPPPPRPPS 467
PPPP PS
Sbjct: 2768 SDDRLSRPPPPATPS 2782
Score = 34.7 bits (78), Expect = 0.37
Identities = 35/110 (31%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query: 396 TISSPKDFGLGQRATPPPPPPPTYRTV-----------VSSPGPGSGPGPGTTSGASSPA 444
T+ S D + P P PPT + +S+P P P P + A SPA
Sbjct: 4868 TLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEE-PSPPPSPLAPSPA 4926
Query: 445 RPAT-PLVPCRS---TTPPPPPPRP------PSRPKLPPGKPGVGDVSRP 484
P T PLV + PP P P P +RPK P G+ SRP
Sbjct: 4927 SPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRP 4976
Score = 33.5 bits (75), Expect = 0.83
Identities = 34/130 (26%), Positives = 52/130 (40%), Gaps = 25/130 (19%)
Query: 147 ALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLE 206
A + P+ P+R A R +SS + R E + K+ + + L PL P +
Sbjct: 4512 AAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLL-PLTEPAIT 4570
Query: 207 SAFDEQKTEVLLDQPEIWGSGQPIN--PSMESPKLTRPFPTG-------------TPPPL 251
+ F L P +GSG P+N + + PTG + PP
Sbjct: 4571 ANFS-------LFAP--FGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPT 4621
Query: 252 PPKNVPATPP 261
PP ++P TPP
Sbjct: 4622 PPSSLPPTPP 4631
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 80.5 bits (197), Expect = 6e-15
Identities = 65/177 (36%), Positives = 71/177 (40%), Gaps = 27/177 (15%)
Query: 337 PATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLET 396
P P +P PLGPPGP GPPGPP PP VL P +A D
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPP-PPGQVLPP--------PLAGPPNRGDRPPPP 276
Query: 397 ISSP-KDFG---LGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVP 452
+ P + FG LG PPPP P Y P P GP P P RP PL P
Sbjct: 277 VLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPP---PPGPFPPRPPGPLGP 333
Query: 453 CRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSS-------SPPPIAPLAR 502
+ PPP P PP P PP P V F PP +S PPP P R
Sbjct: 334 PLTLAPPPHLPGPP--PGAPPPAPHVNPAF--FPPPTNSGMPTSDSRGPPPTDPYGR 386
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/285 (27%), Positives = 88/285 (30%), Gaps = 79/285 (27%)
Query: 244 PTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPS-INDLDSIFGPVLSPK 302
P G PPP P P PP G P GP +V L N D PVL P
Sbjct: 223 PGGPPPPFPAGQTPPRPP-LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP- 280
Query: 303 SVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTG--- 359
P L P PP P P P GPP P G
Sbjct: 281 ----------------GQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFP 324
Query: 360 --PPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPP 417
PPGP GPP + P +L PPP PP
Sbjct: 325 PRPPGPLGPPLTLAPPPHL--------------------------------PGPPPGAPP 352
Query: 418 TYRTVVSSPGPGSGPG---PGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPG 474
P P P P T SG P R P P RPP + G
Sbjct: 353 --------PAPHVNPAFFPPPTNSG--------MPTSDSRGPPPTDPYGRPPPYDRGDYG 396
Query: 475 KPG-VGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAA 518
PG D +R P+ + I RA S+S+IS S ++A
Sbjct: 397 PPGREMDTAR---TPLSEAEFEEIMNRNRAISSSAISRAVSDASA 438
Score = 47.8 bits (112), Expect = 4e-05
Identities = 35/94 (37%), Positives = 36/94 (38%), Gaps = 17/94 (18%)
Query: 414 PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPP------PPRPPS 467
PP + R G G G PG G PA P PPPP PPRPP
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP------GGPPPPFPAGQTPPRPPL 241
Query: 468 RPKLPPGKPG---VGDVSRP--FSPPIHSSSPPP 496
P PPG PG G V P PP PPP
Sbjct: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPP 275
Score = 41.2 bits (95), Expect = 0.004
Identities = 62/226 (27%), Positives = 71/226 (31%), Gaps = 61/226 (26%)
Query: 175 RPRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSM 234
RP P P PP PL GPP D VL GQP
Sbjct: 238 RPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRG--DRPPPPVLFP-------GQPFG--- 285
Query: 235 ESPKLTRPFPTGTPPPLPPKNVP--ATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLD 292
P L P P G PPP+P P PP+ G P GP +
Sbjct: 286 -QPPLG-PLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPP--------------- 328
Query: 293 SIFGPVLSPKSVAVNAEEKWVHFSDTSP------EHVTPELTPREKVVSPPATPDNP-AD 345
GP+ P ++A H P HV P P PP P +D
Sbjct: 329 ---GPLGPPLTLAPPP-----HLPGPPPGAPPPAPHVNPAFFP------PPTNSGMPTSD 374
Query: 346 SPAPGPLG-----PPGPTGPPGPPG----PPRNVLSPLNLEEVQKK 382
S P P PP G GPPG R LS EE+ +
Sbjct: 375 SRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNR 420
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 79.3 bits (194), Expect = 1e-14
Identities = 112/422 (26%), Positives = 147/422 (34%), Gaps = 60/422 (14%)
Query: 150 PSPVRKSPRRSPGA--IKRNLSSEEVARPR--RSTPTPELISKKPPDDTTALAPL-FGPP 204
P+ SP+ SP A + S+ A P + +P + K P A P G P
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071
Query: 205 LESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTG 264
+ T P G P+ SPK P TPP PK ATPP G
Sbjct: 1072 ATPSLKGAPTPPAATPPSPKGG-----PATPSPKGAPMPPAATPPS--PKGGLATPPHKG 1124
Query: 265 SPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVT 324
+P T P + + + P + SPK K + T+P
Sbjct: 1125 APTT--PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG---APTTPAATP 1179
Query: 325 PELTPREKVVSPPATPDNPADSPAP--GPLGPPGPTGPPG-----PPGPPRNVLSPLNLE 377
P SP P PA +P G L P P G P PP P + +P
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP---- 1235
Query: 378 EVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPP-----PP---PPTYRTVVSSPGPG 429
K A T T SPK G ATPPP PP PP+ + +++P
Sbjct: 1236 --SPKGAPTT-----PAATPPSPK----GGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 430 SGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPP-SRPKLPPGKPGVGDVSRPFSPP 488
P P + S PA T+PP P PP + P P G PG +PP
Sbjct: 1285 GAPNPAVVTPPSPKGGPA--------TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
Query: 489 IHSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPSLVWFDRGKFYLTFEGSSRG 548
+ P P A + SS + S+ PT PS +G +T RG
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS----HKGGPAMTPPSPKRG 1392
Query: 549 PS 550
P+
Sbjct: 1393 PA 1394
Score = 77.8 bits (190), Expect = 4e-14
Identities = 104/411 (25%), Positives = 138/411 (33%), Gaps = 80/411 (19%)
Query: 150 PSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLF----GPPL 205
P+ SP+ SPG P + PTP ++ P T L G P
Sbjct: 1313 PAATPPSPKGSPGT-----------PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 206 ESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTR----PFPTGTPP-----PLPPKNV 256
+ E T P P+M P R P P G P PL PK
Sbjct: 1362 TPSSKEGPT------PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
Query: 257 PATPPRTGSPLTIGPGN--DQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVH 314
PATP T G+ + T V ++K P+ + +PK K
Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS----------APKGGPATPSSK--- 1462
Query: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPADSPA-PGPLGPPG-----PTGPPGPPGPPR 368
D + VTP AT +P +PA P P+G P P+ P P P
Sbjct: 1463 -GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
Query: 369 NVLSPL--NLEEVQKKVAEQTFIKDDYLE---TISSPKDFGLGQRATPPPPPPPTYRTVV 423
+ P+ + KK K+ + T+ SPK TP P P
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK-------TPAIPTPKEAPATP 1574
Query: 424 SSPGPGSGPG--PGTTSGASSPAR---PATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGV 478
SS S P P T GA SP P P P PP PPS P+ P P
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS-PEKGPATPA- 1632
Query: 479 GDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPS 529
P + + PP+ P + +S +S +S AT P P+
Sbjct: 1633 ---------PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
Score = 75.1 bits (183), Expect = 2e-13
Identities = 103/418 (24%), Positives = 152/418 (36%), Gaps = 66/418 (15%)
Query: 149 SPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELIS----KKPPDDTTALAPLFGPP 204
SP+ + SP+++P ++ E A P + TP ++ KK P + AP GP
Sbjct: 1404 SPAVIPLSPKKAPAT---PVTREGAATPSKGDLTPPAVTPVSLKKAPATS---APKGGPA 1457
Query: 205 LESAF-DEQKTEVLLDQPEIWGSGQPINPSMESPKL-TRPFPTGTPP-----PLPPKNVP 257
S+ D V P+ + + + S K P P G P P PK VP
Sbjct: 1458 TPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517
Query: 258 ATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVL---SPKSVAVNAEEKWVH 314
ATP P+ +AT + + ++ +++ P + SPK K
Sbjct: 1518 ATPSSRRDPIA------PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP 1571
Query: 315 FSDTS-----PEHVTPEL-----TPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPP 364
+ +S P VTP +P+E ++ P T +P ++P P + PP P P P
Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP 1631
Query: 365 GPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGL----GQRATPPPPPPPTYR 420
P SP + +KD S G + P P +
Sbjct: 1632 APKGTPTSP---------PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALK 1682
Query: 421 TVVSSPGPGSGP--------GPGT-TSGASSPARPATPLV------PCRSTTPPPPPPRP 465
V+ +P P S P GP T S A+SP P P + P P P
Sbjct: 1683 EVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742
Query: 466 PSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPTV 523
K GK P +PP +S P A A E + S+SAA +P V
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTPLTA--AAFEKVLPKPESASVSAAPSPPV 1798
Score = 72.0 bits (175), Expect = 2e-12
Identities = 106/417 (25%), Positives = 141/417 (33%), Gaps = 80/417 (19%)
Query: 151 SPVRKSPRRSP---GAIKRNLSSEEVARPRRSTPTPELIS-----KKPPDDTTALAP--- 199
+PV SP+ P SS+ +P+P +S K+PP + P
Sbjct: 761 APVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820
Query: 200 ---LFGP--PLESAFDEQKTEVLLDQPEIWGSGQPINPSM-ESPKLTRPFPTGTPPP--- 250
L P P+E++F L + + G +P+ SP T P P G P P
Sbjct: 821 IGNLSSPVSPVEASF--------LPENSLSFQGSKDSPATTHSP--TPPSPKGAPTPSAV 870
Query: 251 --LPPKNVPATPPRTGSPLTIG-PGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVN 307
L PK V P T +P + P + ++ P+++ S SPK
Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSS------SPKKARAT 924
Query: 308 AEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPP 367
K + S + TP PATP +P +P P PP P G P P P
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATP-SPKWAPTPPAATPPSPKGGPATPSPK 983
Query: 368 RNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPP---PPPPTYRTVVS 424
P T SPK G ATP P P PP
Sbjct: 984 GAPTPPA--------------------ATPPSPK----GGPATPSPKGAPTPPAVTPPSP 1019
Query: 425 SPGPGSGPGP--GTTSGASSPARP-----ATPLVPCRSTTPPPPPPRPPSRPKLP----- 472
P + P P +T A++P P ATPL TTP P P P P
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 473 PGKPGVGDVSRPFSPPIHSSSPPPIAPLARAES-TSSISSTNSLSAATTPTVENEQP 528
P P S P S P+ P A S +++ A TTP P
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Score = 70.5 bits (171), Expect = 6e-12
Identities = 95/382 (24%), Positives = 129/382 (33%), Gaps = 66/382 (17%)
Query: 151 SPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAFD 210
+P K P A +L P + P P +++ P A +P G P A
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 211 EQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRT-GSPLTI 269
+ P G+ P P +T P P GTP +PAT P + G P T
Sbjct: 1317 PPSPKGSPGTPPPKGAPTP-------PAVTPPSPKGTP------TLPATTPSSKGGPTT- 1362
Query: 270 GPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTP 329
P + + T P GP ++P S P+ P
Sbjct: 1363 -PSSKEGPT-------PPAATPSHKGGPAMTPPS---------------------PKRGP 1393
Query: 330 REKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFI 389
+ SP P +PA P P P G P + L+P + V K A T
Sbjct: 1394 A--IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT-- 1449
Query: 390 KDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPAR-PAT 448
S+PK G ATP PT V+ P P P P + +SSP + PAT
Sbjct: 1450 --------SAPK----GGPATPSSKGDPTL-PAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Query: 449 PLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPL-ARAESTS 507
P T P P P P P + D P + + +P +AP A
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSR---RDPIAPTATLLSKKTPATLAPKEALIPPAM 1553
Query: 508 SISSTNSLSAATTPTVENEQPS 529
++ S A TP PS
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPS 1575
Score = 60.8 bits (146), Expect = 5e-09
Identities = 95/346 (27%), Positives = 127/346 (36%), Gaps = 62/346 (17%)
Query: 230 INPSMESPKLTRPFPTGTPPPLPP----KNVPATPPRTGSPLTIGPGNDQSATEVKIEK- 284
I S+ SP L P GTPP + A P SP P D A+ K
Sbjct: 730 IPKSVPSPSLP---PAGTPPGTKKVDGISHTSALAPVASSPKEC-PTEDSGASATASSKG 785
Query: 285 -LPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPP------ 337
L + D S G +SP++ + K DT +++ ++P E P
Sbjct: 786 TLTYLADSPSPLGVSVSPQTKRPPTK-KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ 844
Query: 338 ATPDNPADSPAPGPLGPPG--------PTGPPGPPGPPRNVLSP--LNLEEVQKKVAEQT 387
+ D+PA + +P P P G P P G PP+ +P +NL ++ A
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 388 FIKDDYLE-TISSPKDFGLGQRATPPP------PPPPTYRTVVSSPGPGSGPGPGTTSGA 440
+ L T SSPK RATP P P P T ++ P GP T S
Sbjct: 905 PKQAPALSMTSSSPKK----ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
Query: 441 SSPARPAT--------PLVPCRSTTPPPPPPRPPS--------RPKLPPGKPGVGDVSRP 484
+P PA P P P PP PPS PK P P V S
Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Query: 485 FSP-----PIHSSSPP---PIAPLARAESTSSISSTNSLSAATTPT 522
SP P +S+PP P +P +T + AAT P+
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Score = 58.5 bits (140), Expect = 2e-08
Identities = 98/419 (23%), Positives = 141/419 (33%), Gaps = 67/419 (15%)
Query: 131 KNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKP 190
K AT+ +A I PSP + +P SS+E + P TP+ + P
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596
Query: 191 PDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPP 250
+ LL P + P+ P +T P P P
Sbjct: 1597 KE------------------------LLIPPAVTSPSPKEAPT--PPAVTPPSPEKGPAT 1630
Query: 251 LPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSIN-DLDSIFGPVLSPKSVAVNAE 309
PK P +PP T S L P + S T +P + L + GP + + A
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690
Query: 310 EKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPT----------- 358
E T+P P+ T + SPP PD A + + GPL P
Sbjct: 1691 ESTPII--TAPTRKGPQ-TKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747
Query: 359 ---------GPPGPPGPPRNVLS-PLNLEEVQKKVAEQTFIKDDYLETISSPK-DFGLGQ 407
P GP PP + S PL +K + K + ++P L
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP-----KPESASVSAAPSPPVSLPL 1802
Query: 408 RATPPPPPPPTYRTVVSSPG----PGSGPGPGTTSGASSPARPATPL---VPCRSTTPPP 460
+P P PP + + SSPG S P P P P+ VP +S
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNM 1862
Query: 461 PPPRPPSRP-KLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAA 518
P P+ P P K V ++ S S + L +ST + + L+AA
Sbjct: 1863 PTPKSAGIPVPTPSAKQPVTKNNK--GSGTESDSDESVPELEEQDSTQATTQQAQLAAA 1919
Score = 55.8 bits (133), Expect = 2e-07
Identities = 90/369 (24%), Positives = 132/369 (35%), Gaps = 60/369 (16%)
Query: 152 PVRKSPRRSPGAIKRNLSSEEVAR---PRRSTPTPELISKKPPDDTTALAPLFGPPLESA 208
P S RR P A L S++ P+ + P + P P P S+
Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS 1576
Query: 209 FDEQKTEVLLDQPEIWGSGQP----INPSMESPKLTR-PFPTGTPPPLP--------PKN 255
E + + G+ P I P++ SP P P PP P PK
Sbjct: 1577 -KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635
Query: 256 VPATPPRTGSPLTIGPGNDQSATEVKIEKLPSIND-LDSIFGPVLSPKSVAVNAEEKWVH 314
P +PP T S L P + S T +P + L + GP + + A E
Sbjct: 1636 TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI 1695
Query: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPL 374
T+P P+ T + SPP PD A + + GPL + ++P
Sbjct: 1696 I--TAPTRKGPQ-TKKSSATSPPICPDPSAKNGSKGPL----------------STVAPA 1736
Query: 375 NLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSG-PG 433
L VQK ++ KD SPK P PP T +++ P
Sbjct: 1737 PLLPVQKDSSKTAKGKD----ASHSPKG--------PLAPPESKASTPLTAAAFEKVLPK 1784
Query: 434 PGTTSGASSPARPAT-PLVPCRSTTPPPPPPRPPSRPKLPPGKPG--VGDVSRPFSPPIH 490
P + S +++P+ P + PL P P P P + + P PG + S+P +P
Sbjct: 1785 PESASVSAAPSPPVSLPLAPS-------PVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
Query: 491 SSSPPPIAP 499
P I P
Sbjct: 1838 DELLPLIPP 1846
Score = 42.0 bits (97), Expect = 0.002
Identities = 105/503 (20%), Positives = 177/503 (35%), Gaps = 86/503 (17%)
Query: 133 AATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPD 192
A +VD+ ++I +I SPS S VA +PT LI K P+
Sbjct: 378 APSVDKGPSTISSITCSPS-----------------GSLNVATSFSLSPTTSLILKSSPN 420
Query: 193 DTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQP--------INPSMESPKLTRPFP 244
T + P+ S T +++ P + ++P M S ++ P
Sbjct: 421 ATYHYPLVAQMPVSSV---GTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEP 477
Query: 245 TGTPP----PLPPKNVPATPPRTG-----SPLTIGPGNDQSATEVKIEKLPSINDLD--- 292
T P+ PK P+T T SP P + ++ + K P+ DL
Sbjct: 478 TSPAALVMAPVAPKE-PSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVP 536
Query: 293 -SIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPR-EKVVSPPATPDNPADSPAPG 350
S+ G SP + ++ P+ +P + S P P +P + A
Sbjct: 537 ASLEGAPFSPAQAGLTTKKDPTVLPLVQ---AAPKNSPSFQSTSSSPEIPLSPEATLAKK 593
Query: 351 PLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDD-----YLETISSPKDFGL 405
LG P P G P ++ SPL + + ++ D ++ +P
Sbjct: 594 SLGEPLPIGKPA-----SSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAF 648
Query: 406 GQRATPPPPPPPTYRTVVSSPGPGSGP---GPGTTSGASSPARPAT----PLVPCRSTTP 458
+ P PT S+ + P G + + + P + T PLVP S
Sbjct: 649 PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENC 708
Query: 459 PPPP------------------PRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPL 500
P P P+ P LPP G ++ H+S+ P+A
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPA--GTPPGTKKVDGISHTSALAPVASS 766
Query: 501 ARAESTSSISSTNSLSAATTPTVENEQPSLVWFD---RGKFYLTFEGSSRGPSPLTMGAQ 557
+ T ++ + S+ T T + PS + + K T +GS+ +P+ +
Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826
Query: 558 DTLPVAAAFTETVNAYFKGADPS 580
PV A+F + F+G+ S
Sbjct: 827 PVSPVEASFLPENSLSFQGSKDS 849
Score = 34.7 bits (78), Expect = 0.37
Identities = 38/137 (27%), Positives = 54/137 (39%), Gaps = 9/137 (6%)
Query: 405 LGQRA-TPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPP 463
LGQ T PPP P + S + P P ++ AS+P P + P P
Sbjct: 38 LGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP 97
Query: 464 RPPS-RPKL--PPGKPGVGDVSRPFSPPIHSSSPPPIAPLAR-AESTSSISSTNSLSAAT 519
P+ P L PP P ++ P P +P APLA A + S+ S+A
Sbjct: 98 EAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQK----SSAF 153
Query: 520 TPTVENEQPSLVWFDRG 536
P + PS+ + G
Sbjct: 154 PPNLLTSPPSVAVAESG 170
Score = 33.5 bits (75), Expect = 0.83
Identities = 49/196 (25%), Positives = 65/196 (33%), Gaps = 54/196 (27%)
Query: 352 LGPPGPT-GPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRAT 410
LG PGPT PP P P + LS N +A+
Sbjct: 38 LGQPGPTLPPPCSPAPQQCPLSAAN--------------------------------QAS 65
Query: 411 PPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPK 470
P P P T + P P S G G A A +P P P + P
Sbjct: 66 PFPSPSTIASTPLEVPFPQSSSGTALPLGT---APEAPTFLPNLIGPPISPAALALASPM 122
Query: 471 LPPGKPGVGDVSRPFS---------------PPIHSSSPPPIAPLARAESTSSISSTNSL 515
+ P G S P + PP +SPP +A AES S I+ + +
Sbjct: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAV---AESGSVITLSAPI 179
Query: 516 SAATTPTVENEQPSLV 531
+ + T N+ PS V
Sbjct: 180 APSEPKTNLNKVPSEV 195
Score = 30.8 bits (68), Expect = 5.4
Identities = 84/348 (24%), Positives = 120/348 (34%), Gaps = 88/348 (25%)
Query: 156 SPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTE 215
SP SP I + EV P+ S+ T L P+ T L L GPP+ A
Sbjct: 65 SPFPSPSTIAS--TPLEVPFPQSSSGTA-LPLGTAPEAPTFLPNLIGPPISPA------A 115
Query: 216 VLLDQPEIWGS--GQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPP-----RTGSPLT 268
+ L P I + G P + + + P PP N+ +PP +GS +T
Sbjct: 116 LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP-NLLTSPPSVAVAESGSVIT 174
Query: 269 IGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEH-VTPEL 327
+ S + + K+PS + + P +P + + T P H VTP
Sbjct: 175 LSAPIAPSEPKTNLNKVPS----EVVPNPKGTPSPPCIVS---------TVPYHCVTPMA 221
Query: 328 TPREKVVSPPAT------------------------PDNPADSPAPGPLGPP-------- 355
+ + V S P T P NP GP+ PP
Sbjct: 222 SIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQ 281
Query: 356 ------------GPTGPPGPPGPPRNVLSPLNLEEV-QKKVAEQT---FIKDDYLETI-- 397
GP PP P + L+PL+ ++ QT + D ++TI
Sbjct: 282 SLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISV 341
Query: 398 --SSPKDFGLGQRATPPPPPPPTY---RTVVSSP--GPGSGPGPGTTS 438
SS QR+ PP P TV + P P GP T S
Sbjct: 342 DHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTIS 389
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 77.8 bits (190), Expect = 4e-14
Identities = 94/351 (26%), Positives = 130/351 (37%), Gaps = 66/351 (18%)
Query: 150 PSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAF 209
PS + P SPG E R R P P++ SK PD P P++S+
Sbjct: 144 PSGPGRFPVPSPG---HRSGPPEPQRNRMPPPRPDVGSK--PDSIPPPVPSTPRPIQSSP 198
Query: 210 DEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTI 269
+ + P + G + +P P PFP L ++ +P + SP +
Sbjct: 199 HNRGS------PPVPGGPRQPSPGPTPP----PFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 270 GPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTP 329
P + + +K P PV + S+ A P P
Sbjct: 249 RPPLPPTPSRALDDKPPPPPP------PVGNRPSIHREA---------------VPPPPP 287
Query: 330 REKVVSPPATPDNPADSPAPGPLGPPGPTGPPG-PPGPPRNVLSPLNLEEVQKKVAEQTF 388
+ P+TP A S AP P PP GPP PP N +P ++ ++
Sbjct: 288 QNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP--------RLPQRNL 339
Query: 389 IKDDYLETISSPKDFGLGQRATPPPP---PPPTYRTVVSSPGPGSGPGPGTTSGASSPAR 445
+ SP G PPPP PPP R GP P P + +G++S A
Sbjct: 340 SLSSSTPPLPSPGRSG----PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRAL 395
Query: 446 PATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPP 496
PATP +P RS PR RP LPP +P G +PP PPP
Sbjct: 396 PATPQLPSRSGV---DSPRSGPRPPLPPDRPSAG------APP-----PPP 432
Score = 60.5 bits (145), Expect = 6e-09
Identities = 70/237 (29%), Positives = 87/237 (36%), Gaps = 55/237 (23%)
Query: 325 PELTP---REKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQK 381
P L P R P + P P P P P GPP P RN + P + K
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPG------HRSGPPEPQRNRMPPPRPDVGSK 179
Query: 382 KVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGA- 440
+ + SSP + R +PP P P SPGP P PG A
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHN-----RGSPPVPGGPRQ----PSPGPTPPPFPGNRGTAL 230
Query: 441 ------------SSP--ARPATPLVPCRSTTPPPPPPRPP--SRPKL-----PP-----G 474
SSP RP P P R+ PPPP PP +RP + PP
Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN 290
Query: 475 KPGVGDVSRPFS--------PPIHSSSPPPIAPLARA-ESTSSISSTN-SLSAATTP 521
KP V RP + PP PPP+ P + + T + N SLS++T P
Sbjct: 291 KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP 347
Score = 33.1 bits (74), Expect = 1.1
Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)
Query: 155 KSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPP----DDTTALAPLFGPPLESAFD 210
++PR + + S+ + P RS P P S++PP D PL PP S +
Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR-N 388
Query: 211 EQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT 268
+ L P++ P ++SP+ +G PPLPP A P P T
Sbjct: 389 GSTSRALPATPQL-----PSRSGVDSPR------SGPRPPLPPDRPSAGAPPPPPPST 435
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 77.8 bits (190), Expect = 4e-14
Identities = 94/351 (26%), Positives = 130/351 (37%), Gaps = 66/351 (18%)
Query: 150 PSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAF 209
PS + P SPG E R R P P++ SK PD P P++S+
Sbjct: 144 PSGPGRFPVPSPG---HRSGPPEPQRNRMPPPRPDVGSK--PDSIPPPVPSTPRPIQSSP 198
Query: 210 DEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTI 269
+ + P + G + +P P PFP L ++ +P + SP +
Sbjct: 199 HNRGS------PPVPGGPRQPSPGPTPP----PFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 270 GPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTP 329
P + + +K P PV + S+ A P P
Sbjct: 249 RPPLPPTPSRALDDKPPPPPP------PVGNRPSIHREA---------------VPPPPP 287
Query: 330 REKVVSPPATPDNPADSPAPGPLGPPGPTGPPG-PPGPPRNVLSPLNLEEVQKKVAEQTF 388
+ P+TP A S AP P PP GPP PP N +P ++ ++
Sbjct: 288 QNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP--------RLPQRNL 339
Query: 389 IKDDYLETISSPKDFGLGQRATPPPP---PPPTYRTVVSSPGPGSGPGPGTTSGASSPAR 445
+ SP G PPPP PPP R GP P P + +G++S A
Sbjct: 340 SLSSSTPPLPSPGRSG----PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRAL 395
Query: 446 PATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPP 496
PATP +P RS PR RP LPP +P G +PP PPP
Sbjct: 396 PATPQLPSRSGV---DSPRSGPRPPLPPDRPSAG------APP-----PPP 432
Score = 60.5 bits (145), Expect = 6e-09
Identities = 70/237 (29%), Positives = 87/237 (36%), Gaps = 55/237 (23%)
Query: 325 PELTP---REKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQK 381
P L P R P + P P P P P GPP P RN + P + K
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPG------HRSGPPEPQRNRMPPPRPDVGSK 179
Query: 382 KVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGA- 440
+ + SSP + R +PP P P SPGP P PG A
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHN-----RGSPPVPGGPRQ----PSPGPTPPPFPGNRGTAL 230
Query: 441 ------------SSP--ARPATPLVPCRSTTPPPPPPRPP--SRPKL-----PP-----G 474
SSP RP P P R+ PPPP PP +RP + PP
Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN 290
Query: 475 KPGVGDVSRPFS--------PPIHSSSPPPIAPLARA-ESTSSISSTN-SLSAATTP 521
KP V RP + PP PPP+ P + + T + N SLS++T P
Sbjct: 291 KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP 347
Score = 33.1 bits (74), Expect = 1.1
Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)
Query: 155 KSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPP----DDTTALAPLFGPPLESAFD 210
++PR + + S+ + P RS P P S++PP D PL PP S +
Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR-N 388
Query: 211 EQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT 268
+ L P++ P ++SP+ +G PPLPP A P P T
Sbjct: 389 GSTSRALPATPQL-----PSRSGVDSPR------SGPRPPLPPDRPSAGAPPPPPPST 435
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 77.4 bits (189), Expect = 5e-14
Identities = 106/460 (23%), Positives = 154/460 (33%), Gaps = 63/460 (13%)
Query: 110 EEESHKKFNIKIKPLQSKDILKNAA-----------TVDELKASIGNIALSPS-----PV 153
E + +KK K KP ++ A T D ++ SP P+
Sbjct: 65 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 124
Query: 154 RKSPRRSPGA-----IKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESA 208
P P + ++ E + +T T + S + TT+ SA
Sbjct: 125 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 184
Query: 209 FDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT 268
D T +L +P P++ +PK P P PK +T P+ +P T
Sbjct: 185 KDLAPTSKVLAKPTPKAETTTKGPALTTPK--------EPTPTTPKEPASTTPKEPTPTT 236
Query: 269 IGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELT 328
I +SA E P+ +PK A ++ + P T +
Sbjct: 237 I-----KSAPTTPKEPAPTTTK-----SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 286
Query: 329 PREKVVSPPATPDNPADS----PAPGPLGPPGPTGPPGP-------PGPPRNVLSPLNLE 377
S P TP PA + PAP P PT P P P P +P +
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346
Query: 378 EVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPP--PTYRTVVSSPGPGSGPGPG 435
E ++ ++PK+ P P P P T S+P P P
Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406
Query: 436 TTSGASSPARPATPLVPCRSTTPPPPPPRP----PSRPKLP-PGKPGVGDVSRPFSP-PI 489
TT A P TP P +TT P P P P+ PK P P P + P P P
Sbjct: 407 TTKSA-----PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 461
Query: 490 HSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPS 529
+ P P P A +T ++ + T T E P+
Sbjct: 462 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501
Score = 72.8 bits (177), Expect = 1e-12
Identities = 100/414 (24%), Positives = 130/414 (31%), Gaps = 69/414 (16%)
Query: 150 PSPVR-KSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESA 208
PSP K P + + E +S PT + K P TT P P E A
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT----TPKEPSPTTTKEPAPTTPKEPA 435
Query: 209 FDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT 268
K P P+ +PK P T P P PK T P+ +P T
Sbjct: 436 PTTPKKPA---------PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 486
Query: 269 IGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELT 328
+ T EKL P K EE + T+PE TP
Sbjct: 487 -----PKKLTPTTPEKL----------APTTPEKPAPTTPEE----LAPTTPEEPTPTTP 527
Query: 329 PREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGP-PGPPRNV-------LSPLNLEEVQ 380
+P A N PAP P PT P P P P+ +P L+E
Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 587
Query: 381 KKVAEQTFIKDDYLETISSPKDFGLGQRA----------TPPPPPPPTYRTVVSSPGPGS 430
++ K+ T P + A TP P P T + + G+
Sbjct: 588 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 647
Query: 431 GPGPGTTSGASSPARPA-------TPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSR 483
P ++P +PA T P +T+ P P P P +P +
Sbjct: 648 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 707
Query: 484 PFSPPIHSSSPPPI-----APLARAEST----SSISSTNSLSAATTPTVENEQP 528
P P +PPP P E T S ST LSA TP P
Sbjct: 708 P--APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 759
Score = 56.2 bits (134), Expect = 1e-07
Identities = 87/365 (23%), Positives = 133/365 (36%), Gaps = 59/365 (16%)
Query: 176 PRRSTPT-PELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQP-----EIWGSGQP 229
P++ TPT PE ++ P+ AP L E+ T ++P + P
Sbjct: 487 PKKLTPTTPEKLAPTTPEKP---APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 543
Query: 230 INPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSIN 289
P+ +PK P P P PK T P+ +P T+ + + T K P+
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL---KEPAPTT---PKKPAPK 597
Query: 290 DLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSP-- 347
+L P + + + ++ + T+P+ P TP+E P TP PA +
Sbjct: 598 EL----APTTTKEPTSTTCDKP----APTTPKGTAPT-TPKEPA---PTTPKEPAPTTPK 645
Query: 348 --APGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGL 405
AP L P PT P P +P L K T D T +PK+
Sbjct: 646 GTAPTTLKEPAPTTPKKP--------APKELAPTTTKGPTST-TSDKPAPT--TPKETA- 693
Query: 406 GQRATPPPPPPPTYRTVVSSPGPGS-GPGPGTTSGASSPARPATPLVPCRS---TTPPPP 461
TP P P T P P + P TTS S+P P +S +TP
Sbjct: 694 --PTTPKEPAP----TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 747
Query: 462 PPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTP 521
P + P +PGV P +++ P + A+ ++T T + P
Sbjct: 748 AEPTPKALENSPKEPGVPTTKTP------AATKPEMTTTAKDKTTERDLRTTPETTTAAP 801
Query: 522 TVENE 526
+ E
Sbjct: 802 KMTKE 806
Score = 50.4 bits (119), Expect = 7e-06
Identities = 91/403 (22%), Positives = 130/403 (32%), Gaps = 36/403 (8%)
Query: 78 SPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIK-IKPLQSKDILKNAATV 136
+P +E P+E T K ++ E + KK K + P +K+
Sbjct: 555 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 614
Query: 137 DELKASIGNIALSPS-PVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTT 195
G +P P +P+ + + + P +TP KKP
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP------KKPAPKEL 668
Query: 196 ALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKN 255
A GP ++ T P+ P P+ +PK +P PT P P +
Sbjct: 669 APTTTKGPTSTTSDKPAPTT-----PKETAPTTPKEPAPTTPK--KPAPTTPETPPPTTS 721
Query: 256 VPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHF 315
+TP T P TI D+S E+ E P + V + K+ A E
Sbjct: 722 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 781
Query: 316 SD--------TSPEHVT--PELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPG 365
D T+PE T P++T + T + T P
Sbjct: 782 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 841
Query: 366 PPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSS 425
L+P KK T I + ET + PKD +AT P P PT +
Sbjct: 842 LKTTTLAPK--VTTTKKTITTTEIMNKPEET-AKPKDRATNSKATTPKPQKPT----KAP 894
Query: 426 PGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSR 468
P S P T P TP R T P P SR
Sbjct: 895 KKPTSTKKPKTMPRVRKPKTTPTP----RKMTSTMPELNPTSR 933
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 77.4 bits (189), Expect = 5e-14
Identities = 106/460 (23%), Positives = 154/460 (33%), Gaps = 63/460 (13%)
Query: 110 EEESHKKFNIKIKPLQSKDILKNAA-----------TVDELKASIGNIALSPS-----PV 153
E + +KK K KP ++ A T D ++ SP P+
Sbjct: 106 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 165
Query: 154 RKSPRRSPGA-----IKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESA 208
P P + ++ E + +T T + S + TT+ SA
Sbjct: 166 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 225
Query: 209 FDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT 268
D T +L +P P++ +PK P P PK +T P+ +P T
Sbjct: 226 KDLAPTSKVLAKPTPKAETTTKGPALTTPK--------EPTPTTPKEPASTTPKEPTPTT 277
Query: 269 IGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELT 328
I +SA E P+ +PK A ++ + P T +
Sbjct: 278 I-----KSAPTTPKEPAPTTTK-----SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 327
Query: 329 PREKVVSPPATPDNPADS----PAPGPLGPPGPTGPPGP-------PGPPRNVLSPLNLE 377
S P TP PA + PAP P PT P P P P +P +
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387
Query: 378 EVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPP--PTYRTVVSSPGPGSGPGPG 435
E ++ ++PK+ P P P P T S+P P P
Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447
Query: 436 TTSGASSPARPATPLVPCRSTTPPPPPPRP----PSRPKLP-PGKPGVGDVSRPFSP-PI 489
TT A P TP P +TT P P P P+ PK P P P + P P P
Sbjct: 448 TTKSA-----PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 502
Query: 490 HSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPS 529
+ P P P A +T ++ + T T E P+
Sbjct: 503 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542
Score = 72.8 bits (177), Expect = 1e-12
Identities = 100/414 (24%), Positives = 130/414 (31%), Gaps = 69/414 (16%)
Query: 150 PSPVR-KSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESA 208
PSP K P + + E +S PT + K P TT P P E A
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT----TPKEPSPTTTKEPAPTTPKEPA 476
Query: 209 FDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLT 268
K P P+ +PK P T P P PK T P+ +P T
Sbjct: 477 PTTPKKPA---------PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 527
Query: 269 IGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELT 328
+ T EKL P K EE + T+PE TP
Sbjct: 528 -----PKKLTPTTPEKL----------APTTPEKPAPTTPEE----LAPTTPEEPTPTTP 568
Query: 329 PREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGP-PGPPRNV-------LSPLNLEEVQ 380
+P A N PAP P PT P P P P+ +P L+E
Sbjct: 569 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 628
Query: 381 KKVAEQTFIKDDYLETISSPKDFGLGQRA----------TPPPPPPPTYRTVVSSPGPGS 430
++ K+ T P + A TP P P T + + G+
Sbjct: 629 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 688
Query: 431 GPGPGTTSGASSPARPA-------TPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSR 483
P ++P +PA T P +T+ P P P P +P +
Sbjct: 689 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 748
Query: 484 PFSPPIHSSSPPPI-----APLARAEST----SSISSTNSLSAATTPTVENEQP 528
P P +PPP P E T S ST LSA TP P
Sbjct: 749 P--APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 800
Score = 56.2 bits (134), Expect = 1e-07
Identities = 87/365 (23%), Positives = 133/365 (36%), Gaps = 59/365 (16%)
Query: 176 PRRSTPT-PELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQP-----EIWGSGQP 229
P++ TPT PE ++ P+ AP L E+ T ++P + P
Sbjct: 528 PKKLTPTTPEKLAPTTPEKP---APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 584
Query: 230 INPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSIN 289
P+ +PK P P P PK T P+ +P T+ + + T K P+
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL---KEPAPTT---PKKPAPK 638
Query: 290 DLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSP-- 347
+L P + + + ++ + T+P+ P TP+E P TP PA +
Sbjct: 639 EL----APTTTKEPTSTTCDKP----APTTPKGTAPT-TPKEPA---PTTPKEPAPTTPK 686
Query: 348 --APGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGL 405
AP L P PT P P +P L K T D T +PK+
Sbjct: 687 GTAPTTLKEPAPTTPKKP--------APKELAPTTTKGPTST-TSDKPAPT--TPKETA- 734
Query: 406 GQRATPPPPPPPTYRTVVSSPGPGS-GPGPGTTSGASSPARPATPLVPCRS---TTPPPP 461
TP P P T P P + P TTS S+P P +S +TP
Sbjct: 735 --PTTPKEPAP----TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 788
Query: 462 PPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTP 521
P + P +PGV P +++ P + A+ ++T T + P
Sbjct: 789 AEPTPKALENSPKEPGVPTTKTP------AATKPEMTTTAKDKTTERDLRTTPETTTAAP 842
Query: 522 TVENE 526
+ E
Sbjct: 843 KMTKE 847
Score = 50.4 bits (119), Expect = 7e-06
Identities = 91/403 (22%), Positives = 130/403 (32%), Gaps = 36/403 (8%)
Query: 78 SPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIK-IKPLQSKDILKNAATV 136
+P +E P+E T K ++ E + KK K + P +K+
Sbjct: 596 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 655
Query: 137 DELKASIGNIALSPS-PVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTT 195
G +P P +P+ + + + P +TP KKP
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP------KKPAPKEL 709
Query: 196 ALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKN 255
A GP ++ T P+ P P+ +PK +P PT P P +
Sbjct: 710 APTTTKGPTSTTSDKPAPTT-----PKETAPTTPKEPAPTTPK--KPAPTTPETPPPTTS 762
Query: 256 VPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHF 315
+TP T P TI D+S E+ E P + V + K+ A E
Sbjct: 763 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 822
Query: 316 SD--------TSPEHVT--PELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPG 365
D T+PE T P++T + T + T P
Sbjct: 823 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 882
Query: 366 PPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSS 425
L+P KK T I + ET + PKD +AT P P PT +
Sbjct: 883 LKTTTLAPK--VTTTKKTITTTEIMNKPEET-AKPKDRATNSKATTPKPQKPT----KAP 935
Query: 426 PGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSR 468
P S P T P TP R T P P SR
Sbjct: 936 KKPTSTKKPKTMPRVRKPKTTPTP----RKMTSTMPELNPTSR 974
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 77.0 bits (188), Expect = 7e-14
Identities = 57/182 (31%), Positives = 66/182 (36%), Gaps = 30/182 (16%)
Query: 330 REKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFI 389
R VVSP P P PGP PG PP PP PP ++
Sbjct: 291 RSSVVSPSHPPPAPPLGSPPGP--KPGFAPPPAPPPPPPPMIG----------------- 331
Query: 390 KDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATP 449
P G G TPPPP PP++ P + P P A P P P
Sbjct: 332 ------IPPPPPPVGFGSPGTPPPPSPPSF---PPHPDFAAPPPPPPPPAADYPTLPPPP 382
Query: 450 LVPCRSTTPPPPPPRPPSRPKLPP--GKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTS 507
L PPPPPP PP P PP G G + P S S P AR++ S
Sbjct: 383 LSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLS 442
Query: 508 SI 509
+I
Sbjct: 443 AI 444
Score = 59.7 bits (143), Expect = 1e-08
Identities = 62/234 (26%), Positives = 79/234 (33%), Gaps = 48/234 (20%)
Query: 316 SDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPP------GPTGPPGPPGPPRN 369
S SP L P PPA P D+ L P P+ PP P PP
Sbjct: 256 SSPSPSFSEDNLPP------PPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPP--PAPP-- 305
Query: 370 VLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPG 429
L + PK G PPPPPPP ++ P P
Sbjct: 306 ------------------------LGSPPGPKP-GFAPPPAPPPPPPP----MIGIPPPP 336
Query: 430 SGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPP---GKPGVGDVSRPFS 486
G G+ P+ P+ P P + PPPPPP P LPP +P G P
Sbjct: 337 PPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPP 396
Query: 487 PPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPSLVWFDRGKFYL 540
PP PPP + S + ++ P V + + L+ R F L
Sbjct: 397 PPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQL 450
Score = 35.8 bits (81), Expect = 0.17
Identities = 31/100 (31%), Positives = 34/100 (34%), Gaps = 17/100 (17%)
Query: 411 PPPP-------PPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPP 463
PPPP P P++ P P P S A P V S PP PP
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
Query: 464 RPPSRPK---LPPGKPGVGDVSRPFSPPIHSSSPPPIAPL 500
P PK PP P P PP PPP P+
Sbjct: 307 GSPPGPKPGFAPPPAP-------PPPPPPMIGIPPPPPPV 339
Score = 32.3 bits (72), Expect = 1.8
Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 14/152 (9%)
Query: 148 LSPS-PVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLE 206
+SPS P P SP K + P P P +I PP PP
Sbjct: 295 VSPSHPPPAPPLGSPPGPKPGFAPPPAPPP----PPPPMIGIPPPPPPVGFGSPGTPPPP 350
Query: 207 SAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPP----- 261
S P P++ P L++P G PPP PP P PP
Sbjct: 351 SPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQP-TGGAPPPPPPPPPPGPPPPPFTG 409
Query: 262 RTGSPLTIGPGNDQSATEVKIEKLPSINDLDS 293
G P P +D + + LP+++D S
Sbjct: 410 ADGQPAIPPPLSDTTKPK---SSLPAVSDARS 438
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 76.3 bits (186), Expect = 1e-13
Identities = 109/415 (26%), Positives = 138/415 (33%), Gaps = 49/415 (11%)
Query: 138 ELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTAL 197
E +S+ + + P P P PG L S + +P T L PP +
Sbjct: 865 ESSSSMPGLGMVPPP----PPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI 920
Query: 198 APLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTG-----TPPPLP 252
P PPL A +L P + G+G P P + + P P PPPLP
Sbjct: 921 PP--PPPLPGAG-------ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLP 971
Query: 253 PKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPS--INDLDSIFGPVLSPKSVAVNA-- 308
+P PP G+ + P + LP I + G + P A
Sbjct: 972 GAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030
Query: 309 ------EEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPG 362
+ P P P PP P A P P PL PG PP
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPP 1088
Query: 363 PPGPPRNVLSPLNLEEV----QKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPT 418
PP P + P L V + L P L PPPPP P
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPR 1148
Query: 419 YRTVVSSPGPGSG-PGPGTTSGASSPARPATPLVPCRSTTP------PPPPPRPPSRPKL 471
P PG+G P P GA P P P V P PPPPP P +
Sbjct: 1149 VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208
Query: 472 PPGKPGVG---DVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPTV 523
PP PG+G + P PP PPP+ P++ + S S TP V
Sbjct: 1209 PPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGS----STLPTPQV 1259
Score = 59.3 bits (142), Expect = 1e-08
Identities = 56/187 (29%), Positives = 67/187 (35%), Gaps = 31/187 (16%)
Query: 318 TSPEH-VTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNL 376
TS EH V+ + SPP P + S PG G PP PP P V +
Sbjct: 839 TSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL----GMVPPPPPPLPGMTVPT---- 890
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGT 436
L + + P+ L PPPPPP + P P PG G
Sbjct: 891 -----------------LPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL--PGAGI 931
Query: 437 TSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPP 496
P P P PPPPP P + LPP PG G P PP+ + PP
Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG---IPPPPPLPGAGIPP 988
Query: 497 IAPLARA 503
PL A
Sbjct: 989 PPPLPGA 995
Score = 42.7 bits (99), Expect = 0.001
Identities = 48/181 (26%), Positives = 69/181 (38%), Gaps = 49/181 (27%)
Query: 357 PTGPPGPPG----PPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPP 412
P PP PPG P S ++L ++++ Q D + T S +
Sbjct: 764 PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQL---DSHQPTQSISQ----------- 809
Query: 413 PPPPPTYRTVVSSPGPGSGPGPGTTS--------GASSPAR-----PATPLVPCRSTT-- 457
PPPPP+ PGS P ++ SS + P+ P +PC ++
Sbjct: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSS 869
Query: 458 -------PPPPPPRP----PSRPKL----PPGKPGVGDVSRPFSPPIHSSSPPPIAPLAR 502
PPPPPP P P+ P PP G ++ P PP+ + PP PL
Sbjct: 870 MPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT-EMLPPPPPPLPGAGIPPPPPLPG 928
Query: 503 A 503
A
Sbjct: 929 A 929
Score = 38.5 bits (88), Expect = 0.026
Identities = 57/235 (24%), Positives = 73/235 (31%), Gaps = 32/235 (13%)
Query: 221 PEIWGSGQPINPSMESPKLTRPFPTG-----TPPPLPPKNVPATPPRTGSPLTIGPGNDQ 275
P + G+G P P + + P P PPPLP +P PP G+ + P
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---- 1144
Query: 276 SATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVS 335
V I P + P L + P P P V
Sbjct: 1145 PLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP---------PPPLPGVGIPPPPPLPGVGI 1195
Query: 336 PPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLE 395
PP P A P P PL G P PP PP P V+ +
Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP---PPPLLPVSGPPLLPQVGSS 1252
Query: 396 TISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPL 450
T+ +P+ G PPP P + G G G+ P RP PL
Sbjct: 1253 TLPTPQVCGF----LPPPLPSGLF-------GLGMNQDKGSRKQPIEPCRPMKPL 1296
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 75.1 bits (183), Expect = 2e-13
Identities = 110/472 (23%), Positives = 159/472 (33%), Gaps = 113/472 (23%)
Query: 138 ELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSE-------EVARPRRSTPTPELISKKP 190
E IG + S R P RS G RN +S E A P ++T + S
Sbjct: 60 ERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
Query: 191 PDDTTALAPLFGPPLESAFDE-----------QKTEVLLDQPEIWGSGQPINPSMESPKL 239
TT PL L + +E +++ + P PS +
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 240 TRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIE-----------KLPSI 288
+R T P P + PP G ++ ++ S TE + P+
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 289 NDLDSIFGPVLSPKSVAVNAE---EKWVHFSDTSPEHV----TPELTPREKVVSPPATP- 340
L S P+ SP +A H S P+ + P++TP K +P P
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 341 -DNPADSPAPG----------------------------PLGPPGPTGPPG-------PP 364
+P +P+P PL PP P+ PP P
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359
Query: 365 GPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPP---PPPPPTYRT 421
PP + L +Q A +F+ L +++P A PP PP PP
Sbjct: 360 TPPSQATTSLGSPTLQ---ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
Query: 422 V--VSSPGP---------------GSGPGPGTTSGASSPARPATPLVPCRSTTPP---PP 461
+ +++P P P P + S PA P P+ P S TPP PP
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP--PVSP--SATPPSQAPP 472
Query: 462 ---------PPRPPSRPKLPPGKPGVGDVSRPF-SPPIHSSSPPPIAPLARA 503
PP PP+ P + P P +PP+ + PPP AP A A
Sbjct: 473 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524
Score = 73.9 bits (180), Expect = 6e-13
Identities = 117/488 (23%), Positives = 160/488 (32%), Gaps = 91/488 (18%)
Query: 87 SIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSKDILKNAA-TVDELKASIGN 145
S RP P K S+SE E S + +P + + A+ ++ + +
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAA---RRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 146 IALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPL 205
A S R +PR + + RP + TP + D AL PL PL
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPALGPLSSSPL 304
Query: 206 ESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNV------PAT 259
+ + L Q P + S+ +L P P P P P ++ PAT
Sbjct: 305 ATP---SPSAALQSQAPPTLPATPHSSSLTC-QLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 260 PPRTG---------------------SPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPV 298
PP SPL P A + + P P+
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
Query: 299 LSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPT 358
+P A NA + + SP P P SPP +P S AP L P
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
Query: 359 GPPGPPG---------PPRNVLSPLNLEEVQ-KKVAEQT--FIKDDYLETISSPKDFGLG 406
PP PP PP PL +Q K Q + L+ + SP G
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540
Query: 407 QR-------------ATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATP---- 449
Q ATPPP PP V+++P P P + +P RP TP
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPP----VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596
Query: 450 ------LVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIH----------SSS 493
L + PPPPP R PS P G + + ++S
Sbjct: 597 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 656
Query: 494 PPPIAPLA 501
PPP A LA
Sbjct: 657 PPPDAELA 664
Score = 73.2 bits (178), Expect = 9e-13
Identities = 100/398 (25%), Positives = 135/398 (33%), Gaps = 81/398 (20%)
Query: 152 PVRKSPRRSPG---AIKRNLSSEEVARPRRSTPTPELISKKP--PDDTTALAPLFGPPLE 206
P+ SP +P A++ A P S+ T +L + P P +A L P
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357
Query: 207 SAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPP-------LPPKNVPAT 259
A + L P + Q + + SP L+ P TPPP LPP P +
Sbjct: 358 PATPPSQATTSLGSPTL----QATHSFLPSPPLS---PLATPPPQAPPALALPPLQAPPS 410
Query: 260 PPRTG--SPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSD 317
PP + SPL +A V + + P F P SP A FS
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAP--------FSPPPSPPVQAP--------FSP 454
Query: 318 TSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPP-GPTGPPGPPGPPRNVLSPLNL 376
+ V+P TP + +PP+ P P P PP P+ P P PP PL L
Sbjct: 455 PASPPVSPSATPPSQ--APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGT 436
A PPP PP T P + P P
Sbjct: 513 --------------------------------AKPPPQAPPALAT----PPLQALPSPPA 536
Query: 437 TSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKL-----PPGKPGVGDVSRPFSPPIHS 491
+ +P P+ L TPPP P + P L PP P + RP +P +
Sbjct: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596
Query: 492 SSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPS 529
S P LA A S + S + P + S
Sbjct: 597 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
Score = 51.2 bits (121), Expect = 4e-06
Identities = 91/377 (24%), Positives = 125/377 (33%), Gaps = 110/377 (29%)
Query: 232 PSMESPKLTRPFPTGTPPPLPP-----------------------------KNVPATPPR 262
P+ +P L P P G+P P PP +P + PR
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 263 TGSPLTIGPGNDQSATEV----KIEKLPSINDLDSIFGPVLSP--------------KSV 304
G + G + A+ + E+ P + GPV SP K +
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP--GPVSSPGRASGTTRPGPLGQKGL 134
Query: 305 AVNAEEKWVHFSDT-SPEHVTPELTPREKVVSP-PATPDNPA---DSPAPGP---LGPPG 356
++AEE T +P+ R P P TP +PA S A G L P
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPA 193
Query: 357 PTGPPGPP--GPPRNVLSPLNLEEVQKKVAEQ-------------TFIKDDYLETISSPK 401
P+ P PP GP ++V S + A + + +SSP
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 402 DFGLGQRATP------------------PPPPPPTYRTVVSSPGPGSGPGPGTTSGASS- 442
G R TP PP P + + GP S T S +++
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAAL 313
Query: 443 -----PARPATP---LVPCRSTTP----PPPPPRPPSRPKLP-----PGKPGVGDVSRPF 485
P PATP + C+ TP PP P PPS LP P + P
Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373
Query: 486 SPPIHSSSP-PPIAPLA 501
HS P PP++PLA
Sbjct: 374 LQATHSFLPSPPLSPLA 390
Score = 50.8 bits (120), Expect = 5e-06
Identities = 63/242 (26%), Positives = 90/242 (37%), Gaps = 45/242 (18%)
Query: 145 NIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPP 204
++A P V SP SP + + + A P + P P ++K PP ALA PP
Sbjct: 473 SLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALAT---PP 527
Query: 205 LESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPK-------NVP 257
L++ L P + P +PS P P TPPP P VP
Sbjct: 528 LQA---------LPSPPASFPGQAPFSPSASLPMS----PLATPPPQAPPVLAAPLLQVP 574
Query: 258 ATPPRTGS------PLTIGPGNDQSATEVKIEKLP------SINDLDSIFGPVLSPKSVA 305
+PP + + P T GP S + + P S + ++ GP L+ S +
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
Query: 306 VNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPG 365
+ + + D+ PE SPP + A PA GP P G PG
Sbjct: 635 ATSTPEELRGYDSGPEGGA--------AASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686
Query: 366 PP 367
P
Sbjct: 687 AP 688
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 74.3 bits (181), Expect = 4e-13
Identities = 98/335 (29%), Positives = 125/335 (37%), Gaps = 78/335 (23%)
Query: 237 PKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFG 296
P L F G P P +TG GPG+ + +LP+ +I G
Sbjct: 96 PTLGDLFAGGFPVLRPAGQRDVAGGKTGQ----GPGSRAPSP-----RLPN----KTISG 142
Query: 297 PVLSPKSVAVNAEEKWVHFSDTSPE--HVTPELTPREKVVSPPATPDNPADSPA------ 348
P++ P S + + + T+P +V P PP P P+ SP
Sbjct: 143 PLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVS 202
Query: 349 -PGPL--------GPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISS 399
PGPL PP P PP PP PP PL V A + + +L I
Sbjct: 203 PPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262
Query: 400 PKDF-------GL-------GQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPAR 445
P GL Q A PP PPP P P P + AS PA
Sbjct: 263 PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP--------PLP---PYASCSPRASLPA- 310
Query: 446 PATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSP----------- 494
P P V S TPPP PP+ PS + PP K G + P +PP S P
Sbjct: 311 PPLPGVNSSSETPPPLPPKSPSF-QAPPQKAGAQALPAPPAPP--GSQPFLQKKRHGRPG 367
Query: 495 -------PPIAPLARAESTSSISSTNSLSAATTPT 522
PP AP AR+ T+ +SS + + A TPT
Sbjct: 368 AGGGKLNPPPAPPARS-PTTELSSKSQQATAWTPT 401
Score = 53.1 bits (126), Expect = 1e-06
Identities = 62/230 (26%), Positives = 76/230 (33%), Gaps = 67/230 (29%)
Query: 334 VSPPATPDNPADSPAPGPLGPPGPTGPPGPP----------GPPRNVLSPLNLEEVQKKV 383
V PP P P P P PLG P P P PP P+ + L + ++
Sbjct: 3 VPPPPPPPLP---PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRL 59
Query: 384 AEQTFIKDDYLETISSPKDF---GLGQRATPPPPPPPTYRTVVSSPGP-----------G 429
+ T I D I S K G G T PPT + + P G
Sbjct: 60 RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119
Query: 430 SGPGPGTTSGASSPARP----ATPLVPCRS--------------TTP-------PPPPPR 464
G G S A SP P + PL+P S T P PPPP
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
Query: 465 PPSRPKLPPGKPGVGDVSRPF---------------SPPIHSSSPPPIAP 499
PP P LPP P + P +PP+ + PPP P
Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPP 229
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/77 (24%), Positives = 30/77 (38%)
Query: 451 VPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSIS 510
+P PPP PP PP PP P VS S + A LA + + +
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
Query: 511 STNSLSAATTPTVENEQ 527
++ + P +E+ +
Sbjct: 61 KVTQINDRSAPQIESSK 77
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 72.4 bits (176), Expect = 2e-12
Identities = 89/341 (26%), Positives = 111/341 (32%), Gaps = 95/341 (27%)
Query: 150 PSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAF 209
PSP SPR+ A+ + E A P++ + PP P PPL +A
Sbjct: 323 PSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAAL 382
Query: 210 DEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPP------RT 263
E + +D ++ P ++ P P P PPPLP + P P T
Sbjct: 383 GEAEPPGPVDATDL--------PKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMST 434
Query: 264 GSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHV 323
S G G + +K E PS L +GP P + + HV
Sbjct: 435 TSSYMSGEGYQSLQSMMKTEG-PSYGALPPAYGP---PAHLPYH-------------PHV 477
Query: 324 TPELTPREKVVSPPATPDNPA-DSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKK 382
P P V PPA+ PA P PG PP P PP PPR L P +
Sbjct: 478 YPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPR--LPPTH------- 528
Query: 383 VAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASS 442
A PP PPP S P P PG
Sbjct: 529 --------------------------AVPPHPPPGLGLPPASYPPPAVPPG--------- 553
Query: 443 PARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSR 483
PP PPP P PPG P VG + R
Sbjct: 554 -------------GQPPVPPPIP------PPGMPPVGGLGR 575
Score = 65.9 bits (159), Expect = 2e-10
Identities = 73/311 (23%), Positives = 103/311 (33%), Gaps = 37/311 (11%)
Query: 212 QKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGP 271
Q +V QP S +P P + P+ P P P++P + + + P
Sbjct: 284 QVPQVQQSQPS--QSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSP 341
Query: 272 GNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPRE 331
+ A E K+P I P L P + + + + T
Sbjct: 342 KEENKAAEPPPPKIPKIETTH----PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLP 397
Query: 332 KVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKD 391
KV PP P P P P PP PP P + + + + + Q+ +K
Sbjct: 398 KVQIPPPAHPAPVHQPPPLPHRPP----PPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKT 453
Query: 392 DYLETISSPKDFG-----------LGQRATPPPPPPPTYR---TVVSSPGPGSGPGPGTT 437
+ + P +G PPP PPP + P PG P P T
Sbjct: 454 EGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTY 513
Query: 438 SGASSPARPATPLVPCRSTTPPPP-----PPRPPSRPKLPPGKPGVGDVSRPFSPPIHSS 492
+ P P P P + P PP PP P +PPG P PPI
Sbjct: 514 NPNFPPPPPRLP--PTHAVPPHPPPGLGLPPASYPPPAVPPGG------QPPVPPPIPPP 565
Query: 493 SPPPIAPLARA 503
PP+ L RA
Sbjct: 566 GMPPVGGLGRA 576
Score = 35.0 bits (79), Expect = 0.29
Identities = 33/124 (26%), Positives = 42/124 (33%), Gaps = 17/124 (13%)
Query: 407 QRATPPP--PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPR 464
Q PP P P + S P S P PA+ P + +P P PR
Sbjct: 272 QLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPR 331
Query: 465 PPSR-----PK-------LPPGKPGVGDVSRPFSPPIH---SSSPPPIAPLARAESTSSI 509
R PK PP K + + P PP H PP A L AE +
Sbjct: 332 QVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPV 391
Query: 510 SSTN 513
+T+
Sbjct: 392 DATD 395
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 72.4 bits (176), Expect = 2e-12
Identities = 70/255 (27%), Positives = 95/255 (37%), Gaps = 37/255 (14%)
Query: 318 TSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPG-PPGPPRNVLSPLNL 376
+S + P+ P ++ +PP P P PL PPGP P G PPGPP
Sbjct: 387 SSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGP--PTGLPPGPPPGA------ 438
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGT 436
+L P G R PP PPP PGP GP PG
Sbjct: 439 --------------PPFLRPPGMPGLRGPLPRLLPPGPPPGR------PPGPPPGPPPGL 478
Query: 437 TSGASSPARPATPLVPCRSTTPPPPPPR---PPSRPKLPPGKPGVGDVSRPFSPPIHSSS 493
G P P L P PPP P PP P L P PG+ + P P S+
Sbjct: 479 PPGPP-PRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPA-PLPNPGVLSA 536
Query: 494 PPPIAPLARAESTS--SISSTNSLSAATTPTVENEQPSLVWFDRGKFYLTFEGSSRGPSP 551
PP + +A+ TS +I + + + P + N + + F + E +P
Sbjct: 537 PPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAP 596
Query: 552 LTMGAQDT-LPVAAA 565
D+ +P+A A
Sbjct: 597 QRKSEDDSAVPLAKA 611
Score = 37.7 bits (86), Expect = 0.044
Identities = 68/312 (21%), Positives = 97/312 (31%), Gaps = 91/312 (29%)
Query: 75 RYNSPELDEEGYSIRPEEPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSKDILKNAA 134
R E+ EEG + + S +SE E++S K+ K D A+
Sbjct: 336 RMAGQEIPEEGREVEEFSEDDDED----DSDDSEAEKQSQKQH----KEESHSDGTSTAS 387
Query: 135 TVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDT 194
+ + ++ PS ++ P P P P P L +PP
Sbjct: 388 SQQQAPPQ----SVPPSQIQAPPMPGPP-------------PLGPPPAPPL---RPPGPP 427
Query: 195 TALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPK 254
T L P GPP L P + G P+ P + P P G PPP PP
Sbjct: 428 TGLPP--GPP-------PGAPPFLRPPGMPGLRGPL-PRLLPPGPPPGRPPG-PPPGPPP 476
Query: 255 NVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVH 314
+P PP G P + P
Sbjct: 477 GLPPGPPPRGPPPRLPP------------------------------------------- 493
Query: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPL 374
+P + P PR ++ PP P PAP L PP P PG P N++
Sbjct: 494 ---PAPPGIPP---PRPGMMRPPLVPPL---GPAPPGLFPPAPLPNPGVLSAPPNLIQRP 544
Query: 375 NLEEVQKKVAEQ 386
++ E+
Sbjct: 545 KADDTSAATIEK 556
Score = 36.2 bits (82), Expect = 0.13
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 2/65 (3%)
Query: 435 GTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSP 494
GT++ +S P + P + PP P P P P PP +P P PP +P
Sbjct: 382 GTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPP--PGAP 439
Query: 495 PPIAP 499
P + P
Sbjct: 440 PFLRP 444
Score = 30.0 bits (66), Expect = 9.2
Identities = 28/108 (25%), Positives = 39/108 (36%), Gaps = 9/108 (8%)
Query: 371 LSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGS 430
L L +E QK+ Y + + + + + P P P+ + P PG+
Sbjct: 107 LRKLEVEYEQKRAQ-----LSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGA 161
Query: 431 GPGP--GTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKP 476
P TS P R + L P PP R P P PPG P
Sbjct: 162 QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGP--PPGPP 207
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 72.0 bits (175), Expect = 2e-12
Identities = 92/375 (24%), Positives = 132/375 (35%), Gaps = 39/375 (10%)
Query: 143 IGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFG 202
+G ++ P P SP I + A PRRS P ++ +PP A PL
Sbjct: 1877 LGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSR-RPSPLAPRPPPSRWASPPL-- 1933
Query: 203 PPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPPKNVPATPPR 262
KT L P + P+ S +L P P +PPP
Sbjct: 1934 ----------KTSPQLRVPPPTSVVTALTPT--SGELAPPGPAPSPPPPEDLGPDFEDME 1981
Query: 263 TGSPLTIGPGNDQSA---TEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDT- 318
S L+ + ++ TE E++ + + S G + +++HF T
Sbjct: 1982 VVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTV 2041
Query: 319 -SPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLE 377
S + P TP + D+ DS A P G PP PG R + +
Sbjct: 2042 VSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGD 2101
Query: 378 EVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTT 437
+ + I D L+ + P D G G R PP PP GS P G T
Sbjct: 2102 RARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPL--------ANGSQPSQGLT 2153
Query: 438 SGASSPAR-----PATPLVPCRSTTPPPPPPRPPSRPKLPPGKPG-----VGDVSRPFSP 487
+ + P R P P V S P P PP+P + + K G + P P
Sbjct: 2154 ASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPP 2213
Query: 488 PIHSSS-PPPIAPLA 501
P+ PP I+P A
Sbjct: 2214 PVKQPPLPPTISPTA 2228
Score = 68.9 bits (167), Expect = 2e-11
Identities = 104/442 (23%), Positives = 149/442 (33%), Gaps = 108/442 (24%)
Query: 108 EEEEESHKKFNIKIKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRN 167
++EEE K+ K K + K+ + A + + A+ A P P P SP
Sbjct: 362 DDEEEEKKEEEEKDKEGEEKE--ERAVAEEMMPAAEKEEAKLPPPPLTPPAPSP------ 413
Query: 168 LSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSG 227
P ++P P L PP + PL PP A +EQ+ P
Sbjct: 414 ---PPPLPPPSTSPPPPLCPPPPPP--VSPPPLPSPPPPPAQEEQEESPPPVVPATCSRK 468
Query: 228 Q---PINPSMESPK-LTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIE 283
+ P+ PS + + R P GT PP P + P SP T+ P +S T +K
Sbjct: 469 RGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSP-TVAP---KSTTFLK-- 522
Query: 284 KLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPE-----HVTPELTPREKVVSPPA 338
++ PV+S +S V + F D P V+P L P + + P
Sbjct: 523 ------NIRQFIMPVVSARSSRVIKTPR--RFMDEDPPKPPKVEVSPVLRP--PITTSPP 572
Query: 339 TPDNPADSPAPG-------------------------------------PLGPPGPTGPP 361
P PA P+P P PP P P
Sbjct: 573 VPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPS 632
Query: 362 GPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPP----- 416
PP P + PL L Q +E E++ +P G + P PPP
Sbjct: 633 PPPAPATSSRRPLLLRAPQFTPSEAHL---KIYESVLTPPPLGAPEAPEPEPPPADDSPA 689
Query: 417 ---------------PTYRTVVSSP---------GPGSGPGPGTTSGASSPARP-ATPLV 451
P + VV++P P GP T + P + T L+
Sbjct: 690 EPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLL 749
Query: 452 PCRSTTPPPPPPRPPSRPKLPP 473
P P P PPS ++PP
Sbjct: 750 PQALPPPQPQLQPPPSPQQMPP 771
Score = 48.9 bits (115), Expect = 2e-05
Identities = 52/190 (27%), Positives = 70/190 (36%), Gaps = 25/190 (13%)
Query: 320 PEHVTPELTPREKVVSPPAT-PDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNL-- 376
P +TP + PP+T P P P P P+ PP PP PP SP +
Sbjct: 403 PPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP 462
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGP--GP 434
+K E ++ G T PP P P+ T P P P P
Sbjct: 463 ATCSRKRGRPPLTPSQRAEREAA----RAGPEGTSPPTPTPS--TATGGP-PEDSPTVAP 515
Query: 435 GTTSGASSPARPATPLVPCRSTTPPPPPPR-----PPSRPKLPPGKPGVGDVSRPFSPPI 489
+T+ + + P+V RS+ P R PP PK+ +VS PPI
Sbjct: 516 KSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKV--------EVSPVLRPPI 567
Query: 490 HSSSPPPIAP 499
+S P P P
Sbjct: 568 TTSPPVPQEP 577
Score = 44.7 bits (104), Expect = 4e-04
Identities = 40/148 (27%), Positives = 59/148 (39%), Gaps = 17/148 (11%)
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGT 436
E+ ++ VAE+ + E P + PPP PPP+ S P P P P
Sbjct: 380 EKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPS----TSPPPPLCPPPPPP 435
Query: 437 TSGASSPARPATPLVPCRSTTPPPPPP----RPPSRPKLPPGKPGVGDVSRP----FSPP 488
S P+ P P + +PPP P R RP L P + + +R SPP
Sbjct: 436 VSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPP 495
Query: 489 IHSSS-----PPPIAPLARAESTSSISS 511
+ S PP +P +ST+ + +
Sbjct: 496 TPTPSTATGGPPEDSPTVAPKSTTFLKN 523
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/153 (24%), Positives = 56/153 (36%), Gaps = 12/153 (7%)
Query: 377 EEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGT 436
EE +K+ E+ ++ E + + ++ PPPP S P P P P T
Sbjct: 365 EEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPL--PPPST 422
Query: 437 TSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSSPPP 496
+ P P+ P +PPPPP + PP P R PP
Sbjct: 423 SPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKR---------GRPP 473
Query: 497 IAPLARAESTSSISSTNSLSAAT-TPTVENEQP 528
+ P RAE ++ + S T TP+ P
Sbjct: 474 LTPSQRAEREAARAGPEGTSPPTPTPSTATGGP 506
Score = 41.6 bits (96), Expect = 0.003
Identities = 71/273 (26%), Positives = 90/273 (32%), Gaps = 69/273 (25%)
Query: 249 PPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNA 308
PP PP A + LT P D + T + P + L GP P A +
Sbjct: 2137 PPAPPL---ANGSQPSQGLTASPA-DPTRTFAWLPGAPGVRVLS--LGPAPEPPKPATS- 2189
Query: 309 EEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPR 368
K + + V ++ + V PP P P + P PT PPGP
Sbjct: 2190 --KIILVNKLGQVFV--KMAGEGEPVPPPVK-----QPPLPPTISPTAPTSWTLPPGPLL 2240
Query: 369 NVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGP 428
VL + + R PPPPPPP T+V S GP
Sbjct: 2241 GVLPVVGVV------------------------------RPAPPPPPPPL--TLVLSSGP 2268
Query: 429 GSGPGP-------GTTSGASSPARP--ATPLVPCRSTTPPPPPPRPP------SRPKL-P 472
S P T SG S PA P P + P P SR ++
Sbjct: 2269 ASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKT 2328
Query: 473 PGKPGVGDVSRPFSPPIHSSSPP-----PIAPL 500
P GV D+ RP P S P P+ PL
Sbjct: 2329 PTVRGVLDLDRPGEPAGEESPGPLQERSPLLPL 2361
Score = 36.2 bits (82), Expect = 0.13
Identities = 62/252 (24%), Positives = 89/252 (35%), Gaps = 25/252 (9%)
Query: 232 PSMESPKLTRPFPTGTPPPLPPKNVPATPPRT-----GSP----LTIGPGNDQSATEVKI 282
P ES P G+ P PA P RT G+P L++GP +
Sbjct: 2131 PREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATS- 2189
Query: 283 EKLPSINDLDSIFGPVLS---PKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPAT 339
K+ +N L +F + P V S T+P T P V+ P
Sbjct: 2190 -KIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVL-PVVG 2247
Query: 340 PDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTF----IKDDYLE 395
PA P P PL +GP PP V ++ + A + + +D
Sbjct: 2248 VVRPAPPPPPPPLTLVLSSGPASPPRQAIRV-KRVSTFSGRSPPAPPPYKAPRLDEDGEA 2306
Query: 396 TISSPKDFGLGQRA-TPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCR 454
+ +P+ GLG + PT R V+ PG G + P + +PL+P
Sbjct: 2307 SEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAG----EESPGPLQERSPLLPLP 2362
Query: 455 STTPPPPPPRPP 466
PP P PP
Sbjct: 2363 EDGPPQVPDGPP 2374
Score = 35.8 bits (81), Expect = 0.17
Identities = 50/189 (26%), Positives = 71/189 (37%), Gaps = 31/189 (16%)
Query: 329 PREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPP--RNVLSPLNLEEVQKKVAEQ 386
PRE+ A +N +P P + PPG PP +VL P E
Sbjct: 1788 PREEPAHLEAAEENQTIVHSPAP-----SSEPPGGEDPPLDTDVLVPGAPE--------- 1833
Query: 387 TFIKDDYLETISSPKDFGLGQRATPPPPPPPTY---RTVVSSPGPGSGPGPGTTSGA-SS 442
+ ++ + P G + PPP P ++ R V + P P G + G S
Sbjct: 1834 ---RHSPIQNLDPPLRPDSG---SAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS 1887
Query: 443 PARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSPPIHSSS----PPPIA 498
P P++ L T P P PP R + P SR SPP+ +S PPP +
Sbjct: 1888 PGSPSS-LTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTS 1946
Query: 499 PLARAESTS 507
+ TS
Sbjct: 1947 VVTALTPTS 1955
Score = 32.3 bits (72), Expect = 1.8
Identities = 52/236 (22%), Positives = 78/236 (33%), Gaps = 55/236 (23%)
Query: 146 IALSPSPVRKSPRRSPGAIKRNLSSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPL 205
++L P+P P S + L V P P + K+PP L P P
Sbjct: 2175 LSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPV-KQPP-----LPPTISPTA 2228
Query: 206 ESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLTRPFPTGTPPPLPP--KNVPATPPRT 263
+++ +L P + + RP P PPPL + PA+PPR
Sbjct: 2229 PTSWTLPPGPLLGVLPVVG--------------VVRPAPPPPPPPLTLVLSSGPASPPRQ 2274
Query: 264 GSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHV 323
++++++ + + P P A +E DT
Sbjct: 2275 A---------------IRVKRVSTFSGRS----PPAPPPYKAPRLDEDGEASEDTPQ--- 2312
Query: 324 TPEL-----------TPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPR 368
P L TP + V P PA +PGPL P P GPP+
Sbjct: 2313 VPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQ 2368
Score = 30.4 bits (67), Expect = 7.0
Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 11/99 (11%)
Query: 327 LTPREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEE----VQKK 382
L + + + P + +SP P GPPGP G GP V++ EE +Q+K
Sbjct: 1016 LAKKGRTIVKTLLPWDSDESPEASP-GPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRK 1074
Query: 383 VAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRT 421
A + + + D + P PP P RT
Sbjct: 1075 SARRCVKQRPSYDIFEDSDD------SEPGGPPAPRRRT 1107
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 70.9 bits (172), Expect = 5e-12
Identities = 67/194 (34%), Positives = 73/194 (37%), Gaps = 51/194 (26%)
Query: 323 VTPELTPREKVVSPPATPDNPADS-------PAPGPLGPPGPTGPPGPPGPPRNVLSPLN 375
V P + R V PPA P P DS PAPG P P PP PP PP P
Sbjct: 563 VPPSVPSRAPV--PPAPP-LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPL----PGG 615
Query: 376 LEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPP--------PPPTYRTVVSSPG 427
+ ISSP G +PPPP PPP V P
Sbjct: 616 V-------------------CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS 656
Query: 428 PGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSP 487
P S PG GT A P P +P + PPPPPP P S PP P G+ P P
Sbjct: 657 PSSLPG-GT-------AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP 708
Query: 488 PIHSSSP--PPIAP 499
P P PP P
Sbjct: 709 PPLPGGPGIPPPPP 722
Score = 50.8 bits (120), Expect = 5e-06
Identities = 47/161 (29%), Positives = 53/161 (32%), Gaps = 33/161 (20%)
Query: 324 TPELTPREKVVSPPATPDNPADSPAPGPL----GPPGPTGPPG----PPGPPRNVLSPLN 375
+P P +SPP A P P PL G P P+ PG PP PP +
Sbjct: 620 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSA--- 676
Query: 376 LEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPG 435
I P G PPPPPP + P P GPG
Sbjct: 677 --------------------RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 716
Query: 436 TTSGASSPARPATPLVPCRSTTPPPPP--PRPPSRPKLPPG 474
P P P P PPPPP P+ P LP G
Sbjct: 717 IPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFG 757
Score = 47.4 bits (111), Expect = 6e-05
Identities = 45/126 (35%), Positives = 52/126 (41%), Gaps = 21/126 (16%)
Query: 405 LGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPP-PP 463
L A PP P+ +P P + P PG SG P PA P STTPPPP PP
Sbjct: 556 LSAAAITVPPSVPS-----RAPVPPAPPLPGD-SGTIIPPPPA----PGDSTTPPPPPPP 605
Query: 464 RPPSRP-------KLPPGKPGVGDVSRPFSPPIHSSSP-PPIAPLARAESTSSISSTNSL 515
PP P PP PG +S P PP+ + PP PL S SS
Sbjct: 606 PPPPPPLPGGVCISSPPSLPGGTAISPP--PPLSGDATIPPPPPLPEGVGIPSPSSLPGG 663
Query: 516 SAATTP 521
+A P
Sbjct: 664 TAIPPP 669
Score = 37.0 bits (84), Expect = 0.075
Identities = 61/267 (22%), Positives = 86/267 (32%), Gaps = 23/267 (8%)
Query: 109 EEEESHKKFNIKIKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNL 168
E ++ F K++ LQ + D L + IA + + G + +
Sbjct: 492 EMKKMESDFEQKLQDLQGEK--------DALHSEKQQIATEKQDLEAEVSQLTGEVAKLT 543
Query: 169 SSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQ 228
E A+ ++ + I+ P + A P PPL + ++ P G
Sbjct: 544 KELEDAKKEMASLSAAAITVPPSVPSRAPVPP-APPLPG-----DSGTIIPPPPAPGDST 597
Query: 229 PINPSMESPKLTRPFPTG----TPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEK 284
P P P P G +PP LP + PP TI P V I
Sbjct: 598 TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP-PPLPEGVGIPS 656
Query: 285 LPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPA 344
S+ +I P P S + + S P P PP P P
Sbjct: 657 PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 716
Query: 345 DSPAP----GPLGPPGPTGPPGPPGPP 367
P P GP PP P G PP PP
Sbjct: 717 IPPPPPFPGGPGIPPPPPGMGMPPPPP 743
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 70.9 bits (172), Expect = 5e-12
Identities = 67/194 (34%), Positives = 73/194 (37%), Gaps = 51/194 (26%)
Query: 323 VTPELTPREKVVSPPATPDNPADS-------PAPGPLGPPGPTGPPGPPGPPRNVLSPLN 375
V P + R V PPA P P DS PAPG P P PP PP PP P
Sbjct: 572 VPPSVPSRAPV--PPAPP-LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPL----PGG 624
Query: 376 LEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPP--------PPPTYRTVVSSPG 427
+ ISSP G +PPPP PPP V P
Sbjct: 625 V-------------------CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS 665
Query: 428 PGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFSP 487
P S PG GT A P P +P + PPPPPP P S PP P G+ P P
Sbjct: 666 PSSLPG-GT-------AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP 717
Query: 488 PIHSSSP--PPIAP 499
P P PP P
Sbjct: 718 PPLPGGPGIPPPPP 731
Score = 50.8 bits (120), Expect = 5e-06
Identities = 47/161 (29%), Positives = 53/161 (32%), Gaps = 33/161 (20%)
Query: 324 TPELTPREKVVSPPATPDNPADSPAPGPL----GPPGPTGPPG----PPGPPRNVLSPLN 375
+P P +SPP A P P PL G P P+ PG PP PP +
Sbjct: 629 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSA--- 685
Query: 376 LEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPG 435
I P G PPPPPP + P P GPG
Sbjct: 686 --------------------RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 725
Query: 436 TTSGASSPARPATPLVPCRSTTPPPPP--PRPPSRPKLPPG 474
P P P P PPPPP P+ P LP G
Sbjct: 726 IPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFG 766
Score = 47.4 bits (111), Expect = 6e-05
Identities = 45/126 (35%), Positives = 52/126 (41%), Gaps = 21/126 (16%)
Query: 405 LGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPP-PP 463
L A PP P+ +P P + P PG SG P PA P STTPPPP PP
Sbjct: 565 LSAAAITVPPSVPS-----RAPVPPAPPLPGD-SGTIIPPPPA----PGDSTTPPPPPPP 614
Query: 464 RPPSRP-------KLPPGKPGVGDVSRPFSPPIHSSSP-PPIAPLARAESTSSISSTNSL 515
PP P PP PG +S P PP+ + PP PL S SS
Sbjct: 615 PPPPPPLPGGVCISSPPSLPGGTAISPP--PPLSGDATIPPPPPLPEGVGIPSPSSLPGG 672
Query: 516 SAATTP 521
+A P
Sbjct: 673 TAIPPP 678
Score = 37.0 bits (84), Expect = 0.075
Identities = 61/267 (22%), Positives = 86/267 (32%), Gaps = 23/267 (8%)
Query: 109 EEEESHKKFNIKIKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNL 168
E ++ F K++ LQ + D L + IA + + G + +
Sbjct: 501 EMKKMESDFEQKLQDLQGEK--------DALHSEKQQIATEKQDLEAEVSQLTGEVAKLT 552
Query: 169 SSEEVARPRRSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQ 228
E A+ ++ + I+ P + A P PPL + ++ P G
Sbjct: 553 KELEDAKKEMASLSAAAITVPPSVPSRAPVPP-APPLPG-----DSGTIIPPPPAPGDST 606
Query: 229 PINPSMESPKLTRPFPTG----TPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEK 284
P P P P G +PP LP + PP TI P V I
Sbjct: 607 TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP-PPLPEGVGIPS 665
Query: 285 LPSINDLDSIFGPVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPA 344
S+ +I P P S + + S P P PP P P
Sbjct: 666 PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 725
Query: 345 DSPAP----GPLGPPGPTGPPGPPGPP 367
P P GP PP P G PP PP
Sbjct: 726 IPPPPPFPGGPGIPPPPPGMGMPPPPP 752
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.131 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,511,823
Number of Sequences: 37866
Number of extensions: 3369178
Number of successful extensions: 80942
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 889
Number of HSP's successfully gapped in prelim test: 1952
Number of HSP's that attempted gapping in prelim test: 19872
Number of HSP's gapped (non-prelim): 25215
length of query: 828
length of database: 18,247,518
effective HSP length: 111
effective length of query: 717
effective length of database: 14,044,392
effective search space: 10069829064
effective search space used: 10069829064
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.