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Search of human proteins with 239508792
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239508792 PREDICTED: NAC alpha domain containing [Homo
sapiens]
(1522 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens] 3006 0.0
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens] 3006 0.0
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens] 3004 0.0
gi|226437579 NAC alpha domain containing [Homo sapiens] 2986 0.0
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens] 2986 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 319 1e-86
gi|163965362 nascent polypeptide-associated complex alpha subuni... 243 8e-64
gi|5031931 nascent polypeptide-associated complex alpha subunit ... 243 8e-64
gi|163965364 nascent polypeptide-associated complex alpha subuni... 243 8e-64
gi|40548328 nascent-polypeptide-associated complex alpha polypep... 222 2e-57
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 107 7e-23
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 100 2e-20
gi|91982772 mucin 17 [Homo sapiens] 96 3e-19
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 91 9e-18
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 91 9e-18
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 89 3e-17
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 87 9e-17
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 87 9e-17
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 86 2e-16
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 83 2e-15
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 82 5e-15
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 81 9e-15
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 81 9e-15
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 81 9e-15
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 79 4e-14
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 79 4e-14
gi|167736355 mucin 4 isoform a [Homo sapiens] 77 1e-13
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 76 2e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 76 3e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 72 4e-12
>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 3006 bits (7793), Expect = 0.0
Identities = 1522/1522 (100%), Positives = 1522/1522 (100%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV
Sbjct: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL 900
AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL
Sbjct: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL 900
Query: 901 AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 960
AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ
Sbjct: 901 AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 960
Query: 961 DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT 1020
DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT
Sbjct: 961 DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT 1020
Query: 1021 GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL 1080
GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL
Sbjct: 1021 GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL 1080
Query: 1081 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ 1140
SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ
Sbjct: 1081 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ 1140
Query: 1141 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL 1200
QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL
Sbjct: 1141 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL 1200
Query: 1201 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS 1260
PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS
Sbjct: 1201 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS 1260
Query: 1261 PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP 1320
PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP
Sbjct: 1261 PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP 1320
Query: 1321 RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA 1380
RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA
Sbjct: 1321 RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA 1380
Query: 1381 MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA 1440
MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA
Sbjct: 1381 MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA 1440
Query: 1441 AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA 1500
AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA
Sbjct: 1441 AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA 1500
Query: 1501 KAVRALRDNHSDIVNAIMELTM 1522
KAVRALRDNHSDIVNAIMELTM
Sbjct: 1501 KAVRALRDNHSDIVNAIMELTM 1522
>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 3006 bits (7793), Expect = 0.0
Identities = 1522/1522 (100%), Positives = 1522/1522 (100%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV
Sbjct: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL 900
AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL
Sbjct: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL 900
Query: 901 AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 960
AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ
Sbjct: 901 AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 960
Query: 961 DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT 1020
DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT
Sbjct: 961 DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT 1020
Query: 1021 GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL 1080
GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL
Sbjct: 1021 GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL 1080
Query: 1081 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ 1140
SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ
Sbjct: 1081 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ 1140
Query: 1141 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL 1200
QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL
Sbjct: 1141 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL 1200
Query: 1201 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS 1260
PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS
Sbjct: 1201 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS 1260
Query: 1261 PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP 1320
PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP
Sbjct: 1261 PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP 1320
Query: 1321 RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA 1380
RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA
Sbjct: 1321 RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA 1380
Query: 1381 MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA 1440
MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA
Sbjct: 1381 MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA 1440
Query: 1441 AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA 1500
AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA
Sbjct: 1441 AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA 1500
Query: 1501 KAVRALRDNHSDIVNAIMELTM 1522
KAVRALRDNHSDIVNAIMELTM
Sbjct: 1501 KAVRALRDNHSDIVNAIMELTM 1522
>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 3004 bits (7787), Expect = 0.0
Identities = 1520/1522 (99%), Positives = 1522/1522 (100%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA+EDLTLPQDS
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAEEDLTLPQDS 600
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV
Sbjct: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT+VSQQAEEGLTLPQDS
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 840
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL 900
AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL
Sbjct: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPL 900
Query: 901 AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 960
AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ
Sbjct: 901 AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 960
Query: 961 DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT 1020
DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT
Sbjct: 961 DDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT 1020
Query: 1021 GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL 1080
GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL
Sbjct: 1021 GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL 1080
Query: 1081 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ 1140
SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ
Sbjct: 1081 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ 1140
Query: 1141 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL 1200
QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL
Sbjct: 1141 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL 1200
Query: 1201 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS 1260
PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS
Sbjct: 1201 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS 1260
Query: 1261 PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP 1320
PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP
Sbjct: 1261 PHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSP 1320
Query: 1321 RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA 1380
RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA
Sbjct: 1321 RALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKA 1380
Query: 1381 MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA 1440
MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA
Sbjct: 1381 MSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAA 1440
Query: 1441 AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA 1500
AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA
Sbjct: 1441 AEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRA 1500
Query: 1501 KAVRALRDNHSDIVNAIMELTM 1522
KAVRALRDNHSDIVNAIMELTM
Sbjct: 1501 KAVRALRDNHSDIVNAIMELTM 1522
>gi|226437579 NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 2986 bits (7742), Expect = 0.0
Identities = 1522/1562 (97%), Positives = 1522/1562 (97%), Gaps = 40/1562 (2%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV
Sbjct: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMT----------------- 883
AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMT
Sbjct: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
Query: 884 -----------------------APLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
APLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP
Sbjct: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
Query: 921 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 980
VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD
Sbjct: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
Query: 981 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1040
STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ
Sbjct: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
Query: 1041 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1100
EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP
Sbjct: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
Query: 1101 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1160
SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV
Sbjct: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
Query: 1161 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220
LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE
Sbjct: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
Query: 1221 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1280
DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL
Sbjct: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
Query: 1281 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1340
QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD
Sbjct: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
Query: 1341 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1400
EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS
Sbjct: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
Query: 1401 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1460
KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR
Sbjct: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
Query: 1461 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1520
PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL
Sbjct: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
Query: 1521 TM 1522
TM
Sbjct: 1561 TM 1562
>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 2986 bits (7742), Expect = 0.0
Identities = 1522/1562 (97%), Positives = 1522/1562 (97%), Gaps = 40/1562 (2%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV
Sbjct: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMT----------------- 883
AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMT
Sbjct: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
Query: 884 -----------------------APLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
APLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP
Sbjct: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
Query: 921 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 980
VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD
Sbjct: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
Query: 981 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1040
STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ
Sbjct: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
Query: 1041 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1100
EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP
Sbjct: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
Query: 1101 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1160
SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV
Sbjct: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
Query: 1161 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220
LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE
Sbjct: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
Query: 1221 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1280
DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL
Sbjct: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
Query: 1281 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1340
QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD
Sbjct: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
Query: 1341 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1400
EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS
Sbjct: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
Query: 1401 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1460
KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR
Sbjct: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
Query: 1461 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1520
PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL
Sbjct: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
Query: 1521 TM 1522
TM
Sbjct: 1561 TM 1562
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 319 bits (817), Expect = 1e-86
Identities = 442/1571 (28%), Positives = 589/1571 (37%), Gaps = 247/1571 (15%)
Query: 82 AWADPGEGGP---SPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTA 138
++A P GP S ++ P + A E+ PA + P G T SP T
Sbjct: 625 SYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
Query: 139 LRDQEG-----GHASPDPPPELCSQGDLSVPSPPPDPDSFFT---PPSTPTKTTYALLPA 190
+ G + P S+ PSP T P P LP
Sbjct: 682 SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741
Query: 191 CGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSG 250
G + + L +SP G S +S +L+ LA + P G
Sbjct: 742 AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS---PLG 798
Query: 251 WGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAAL 310
+SPQ T PP+ + S D+ G+ +P
Sbjct: 799 VSVSPQ-------------TKRPPTKKGSAGPDTPI-----GNLSSPVSPVEASFLPENS 840
Query: 311 LPFQGSLIFQVEAVEVTPLSPEEEEEEAVADP-DPGGDLAGEGEEDSTSASFLQSLSDLS 369
L FQGS TP SP+ + P P G E + S L +
Sbjct: 841 LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
Query: 370 ITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGG 429
T +A A S SS A A S P T GG
Sbjct: 901 ATPAPKQAPAL----SMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGG 953
Query: 430 GAKGLQAQDGTVSWAVE--AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHT 487
A + WA AA S +G + + + AT +P
Sbjct: 954 PATP------SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 488 LQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL----GQESVTA 543
P + T +P+ T G + A P PS +G G + A
Sbjct: 1008 APTPPAV-----TPPSPKGSPAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPA 1061
Query: 544 EKLPTPQ---EETSLTLCPDSPQNL--KEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQ 598
LP+P+ SL P P +GG PS + P K L P
Sbjct: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 599 DS------AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE 652
A TPP P + P P A T + P+ + TPP T
Sbjct: 1122 HKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPS----PKGGLATPPPKGAPTT 1174
Query: 653 LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ---Q 709
++ P P L + + T P A TPP P + P P A T +
Sbjct: 1175 PAATP-PSPKGGLATPSPKGAPTTP---AATPPSPKGGL---ATPSPKGAPTTPAATPPS 1227
Query: 710 AEEGLTLPQDS------AMTPPLPLQDTDL---SSAPKPVAAATLVSQQAEEGLTLP--- 757
+ GL P A TPP P AP P AA + GL P
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP---PSLKGGLATPPHK 1284
Query: 758 ---QDSAMTPPLPLQDTDLS---SAPKPVAAATIVSQQAEEGLTLPQDS----AMTPPLP 807
+ +TPP P S AP P AAT S + G P+ + A+TPP P
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 808 LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS-------AMTPPLPLQDTDLSS----- 855
+ T A P + + ++EG T P + AMTPP P + + S
Sbjct: 1344 -KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 856 --------APKPVAAATPVSQQAEEGLTLPQDSAMT----APLPLQDTGPTSGPEPLAVA 903
+PK A ATPV++ EG P +T P+ L+ TS P+ A
Sbjct: 1403 TSPAVIPLSPKK-APATPVTR---EGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPA 1457
Query: 904 TPQ-----TLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKN--------AALPTVP 950
TP TL A +P P A ++V + P+ AP A +P+ P
Sbjct: 1458 TPSSKGDPTLPAVTPPSPKEPP----APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
Query: 951 EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGR 1010
+ + DP A T + +TL + +P + + A+ P
Sbjct: 1514 KEVPATPSSRRDPI----APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK- 1568
Query: 1011 EACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA 1070
EA A T + SP T + +G P P +E P PPA
Sbjct: 1569 ----EAPA-TPSSKEASSPPAVT---PSTYKGAPSPKELLIPPAVTSPSPKEAP-TPPAV 1619
Query: 1071 CPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA-VSSLDRGCPD 1129
P + +PA + G T P PS++ + + +GA V +G P
Sbjct: 1620 TPPSPEKGPATPAPK-----GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
Query: 1130 APAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLA-KGQPSTPVDRPLGPD 1188
PT+ +++ P+ TP++ P + + S+ P+ PD
Sbjct: 1675 KKGPTA---------------LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
Query: 1189 PSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE-------DEEPPGSLGLPPPQAGVQPAA 1241
PSA G PL AP Q+DS + P G L PP P
Sbjct: 1720 PSAKNGSKG----PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA-PPESKASTPLT 1774
Query: 1242 AAVSGTTQPLGTGPRVSLSPHSPLLSP----KVASMDAKDLALQILPPCQVPPPSGPQSP 1297
AA P VS +P P+ P V ++ K L P + PS P +P
Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
Query: 1298 AG--------------------------PQGLSAPEQQEDEDSLEEDSPRALGSGQHSDS 1331
A P SA + + + GSG SDS
Sbjct: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1894
Query: 1332 HGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQG 1391
ES EL+EQD T Q A A EE ++KAKQSRSEKKARKAMSKLGLRQ+ G
Sbjct: 1895 D-ESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTG 1953
Query: 1392 VTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPS 1451
VTR+TI+KSKNILFVI KPDV+KSPASDTY+VFGEAKIEDLSQQ AAAEKFKV E
Sbjct: 1954 VTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAV 2013
Query: 1452 ALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHS 1511
+ + E+ P V +EE EEEEVDE G+E++DIELVM+QANVSRAKAVRAL++N +
Sbjct: 2014 SNIQENTQTPTV------QEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSN 2067
Query: 1512 DIVNAIMELTM 1522
DIVNAIMELTM
Sbjct: 2068 DIVNAIMELTM 2078
Score = 92.4 bits (228), Expect = 3e-18
Identities = 205/872 (23%), Positives = 299/872 (34%), Gaps = 154/872 (17%)
Query: 529 QEGISEILGQESVTAEKLPTPQ-EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVP 587
Q G++ + T + +PQ ++T+++ SPQN G L L P AA ++
Sbjct: 224 QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN---PGSLSLKGPVSPPAALSL-S 279
Query: 588 RQAKEDLTLPQDSA--MTPP----------LPLQDTDLSS----------APKPVAAATI 625
Q+ +T Q +A TPP PL + S A TI
Sbjct: 280 TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339
Query: 626 VSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 685
+ G + P + PPLP ++ + P VAA +V+ ++G + +P
Sbjct: 340 SVDHSSTGASYPSQRSVIPPLPSRNEVV---PATVAAFPVVAPSVDKGPSTISSITCSPS 396
Query: 686 -----------LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 734
P L S+P LV+Q +P S T PL + +
Sbjct: 397 GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ-------MPVSSVGTTPLVVTN---- 445
Query: 735 SAPKPVAAATLVSQQAEEGLTLPQDSAM------TPPLPLQDTDLSSAPKPVAAATIVSQ 788
P +AAA + + ++ P S T P L ++ AT +
Sbjct: 446 --PCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRI 503
Query: 789 QAEEGLTLPQD-----SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT 843
L P+D S++ P Q DL + P + A QA GLT +D +
Sbjct: 504 PVSPPLPDPEDLKNLPSSVLVKFPTQK-DLQTVPASLEGAPFSPAQA--GLTTKKDPTVL 560
Query: 844 PPLPLQDTDL----SSAPKPVAAATPVSQQAEEGLTLPQD-----SAMTAPLPLQDT--- 891
P + + S++ P +P + A++ L P S+MT+PL + +
Sbjct: 561 PLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV 620
Query: 892 -------GPTS-GP-------EPLAVATPQTLQAEAGCAP----GTEPVATMAQQ--EVG 930
GP S GP P A P AG AP GT T A E
Sbjct: 621 IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680
Query: 931 EALGPR--PAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEAL 988
+L P+ P E LP VP + V A T A E S + +
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKS---VPSP 737
Query: 989 SLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA 1048
SLP + G + + +S HT A S KE ++ G A
Sbjct: 738 SLPPAGTPPGTKKVDGIS------------HTSALAPVASSPKEC----PTEDSGASATA 781
Query: 1049 QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVA-TEA 1107
G + L D+P VS P + +G +G TP L S V+ EA
Sbjct: 782 SSKGTLTYLA------DSPSPLGVSVSPQTKRPPTK--KGSAGPDTPIGNLSSPVSPVEA 833
Query: 1108 SLDSCPESSVGAVSSLDRGC----PDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGT 1163
S PE+S+ S D P P+P APT P+ G P E P+
Sbjct: 834 SF--LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891
Query: 1164 PLLQPPENLAKGQPSTPVDRP---LGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220
L P E P+TP + L S+P P P +P P +
Sbjct: 892 NLPFPKEG-----PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946
Query: 1221 DEEPPGSLGLPPPQ------AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMD 1274
P G P P+ A P+ T P G + +P SP P S
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006
Query: 1275 AKDLALQILPPCQVPPPSGPQSPAGPQGLSAP 1306
+ PP P P + P+G S P
Sbjct: 1007 GAPTPPAVTPP---SPKGSPAATPFPKGASTP 1035
Score = 92.4 bits (228), Expect = 3e-18
Identities = 226/994 (22%), Positives = 338/994 (34%), Gaps = 184/994 (18%)
Query: 474 ALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM-PQPSQEGI 532
++G P T+ AP EVAT V+P + AA+ M P +E
Sbjct: 435 SVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494
Query: 533 SEILGQESV-TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA- 590
+++ + + LP P++ +L S +K DL + + A P QA
Sbjct: 495 TQVATTLRIPVSPPLPDPEDLKNL----PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
Query: 591 ----KEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA-AATIVSQQAEEGLTLPQD-SVMTP 644
K+ LP A P + SS P++ AT+ + E L + + S MT
Sbjct: 551 LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
Query: 645 PLPLQD------TELSSAPK---PVAAATLVS--------QQAEEGLTLP-----QDSAM 682
PL + T+ + P P+ ++L++ + A+ P +
Sbjct: 611 PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYT 670
Query: 683 TPPLPLQDTDLSSAPK--PVAAATLVS----QQAEEGLTL---PQDS-AMTPPLPLQDTD 732
T P + +S APK PV TL + A E + PQ++ A L L
Sbjct: 671 TTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEI 730
Query: 733 LSSAPKP--VAAATLVSQQAEEGLTLPQDSAMTP------PLPLQD-------------T 771
S P P A T + +G++ SA+ P P +D T
Sbjct: 731 PKSVPSPSLPPAGTPPGTKKVDGIS--HTSALAPVASSPKECPTEDSGASATASSKGTLT 788
Query: 772 DLSSAPKPVAAATI------VSQQAEEGLTLPQDSAMTPPLPLQDTDLSS---------- 815
L+ +P P+ + +++ G P + +P P++ + L
Sbjct: 789 YLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848
Query: 816 -----------APKPVAAATIVSQQAEEGLTLPQDSAMTP-----PLPLQDTDLSSAPKP 859
+PK + V+ + +G+TLP TP P P ++ + APK
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP-KEGPATPAPKQ 907
Query: 860 VAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAP--- 916
A + S ++ P + A P P P A P A +P
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPA-----SPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 917 GTEPVATMAQQEVGEAL-GPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAA 975
T P AT + G A P+ AP A T P P P A TP +
Sbjct: 963 PTPPAATPPSPKGGPATPSPKGAPTPPAA---TPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 976 QEDADSTLGMEALSLPEPAS---------------GAGEEIAEALSRP-GREACLEAR-A 1018
+ +T + S P A+ GA A L P G A + A
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 1019 HTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALG-----GAREVPDAPP----- 1068
T A P SP K + + + P A P+ L GA P A P
Sbjct: 1080 PTPPAATPPSP-KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 1069 -AACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGC 1127
A P A A G +TP P A T A+ P+ G + +G
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPP--KGAPTTPAATPPSPKG--GLATPSPKGA 1194
Query: 1128 PDAPAPT-----------------SAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPE 1170
P PA T + P + P P GL + P P+ TP PP
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL-ATPSPKGAPT---TPAATPPS 1250
Query: 1171 NLAKGQPSTPVDR--PLGPDPSAPGTLAGAALPPLE-PPAPCLCQDPQEDSVEDEEPPGS 1227
KG P+TP + P P + P G A PP + P P + P PP
Sbjct: 1251 --PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP-- 1306
Query: 1228 LGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQ 1287
G P P A P+ GT P G +++P SP +P L P
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP----------TLPATTPSS 1356
Query: 1288 VPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPR 1321
P+ P S GP +A + ++ SP+
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390
Score = 85.9 bits (211), Expect = 3e-16
Identities = 209/1020 (20%), Positives = 346/1020 (33%), Gaps = 145/1020 (14%)
Query: 13 PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72
P + + GP T A + + A TP P + + P + P
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 73 DAGPGGAPSAWADPGEGGPSPMLL-------------PEGLSSQALSTEAPL-PATLEPR 118
G P+A +GGP+ L P+G + AP+ PA P
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 119 IVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVP--SPPPDPDSFFTP 176
G T +P +GG A+P P +G + P +PP TP
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPP------KGAPTTPAATPPSPKGGLATP 1166
Query: 177 PSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSL 236
P TT A P G A S +PP SP G T ++P+ +
Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATP 1225
Query: 237 SLLAPAEGLDFPSGWGL---------SPQGSMVDERELHPAGTPEPPSSESSLSADSSSS 287
+P GL PS G SP+G P G P PP++ ++
Sbjct: 1226 P--SPKGGLATPSPKGAPTTPAATPPSPKGGPATP---PPKGAPTPPAATPPSLKGGLAT 1280
Query: 288 WGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGG- 346
+G A +P + P G + P + + + P P G
Sbjct: 1281 PPHKG--------APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
Query: 347 ---------DLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397
G +T+ S + S EG A + S
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
Query: 398 EADDERLYSGEPHAQATL-----LQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTS 452
A G+P + A + + T E + +KG +++ AP TS
Sbjct: 1393 PAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
Query: 453 -DRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEET 511
+G + + G + VTP + + P + +VAT +P+ T
Sbjct: 1451 APKGGPATPSSK------------GDPTLPAVTPPSPKEPPAPK-QVATSSSPKKA-PAT 1496
Query: 512 DSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGL 571
+ G + +P +E + + A ++T TL +P+ +
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL---APKEALIPPAM 1553
Query: 572 DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631
+PS +K A T P+++ TP + +S+P V +T +
Sbjct: 1554 TVPSPKKTPAIPT------------PKEAPATP-----SSKEASSPPAVTPSTYKGAPSP 1596
Query: 632 EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691
+ L +P +T P P AP P A + E+G P P+ +
Sbjct: 1597 KELLIP--PAVTSPSP------KEAPTPPA---VTPPSPEKGPATPAPKGTPTSPPVTPS 1645
Query: 692 DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSAPKPVAAATLVS 747
L +P A+ T + G T+PQ S P P L++ ++ AP+ + +++
Sbjct: 1646 SLKDSPTSPASVT-----CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIIT 1697
Query: 748 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP---VAAATIVSQQAEEGLTLP-QDSAMT 803
+G + SA +PP+ + + + P VA A ++ Q + T +D++ +
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 804 PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863
P PL AP A+T ++ A E + +SA P L AP PV
Sbjct: 1758 PKGPL-------APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
Query: 864 TPVSQ--QAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLA-----------VATPQTLQA 910
P Q + GL L S AP + P PEP++ + TP++
Sbjct: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI 1870
Query: 911 EAGCAPGTEPVATMAQQEVGEALGPRPAPE-EKNAALPTVPEPAALDQVQQDDPQPAAEA 969
+PV + E+ PE E+ + + A L + D +P ++A
Sbjct: 1871 PVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
Score = 66.2 bits (160), Expect = 2e-10
Identities = 224/1033 (21%), Positives = 329/1033 (31%), Gaps = 252/1033 (24%)
Query: 478 ESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------------------ES 519
E+T TV P T Q P Q E A V P + + GQ +
Sbjct: 4 EATETV-PATEQELPQPQAETA--VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
Query: 520 AAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTL----CPDSPQNLKEEGGLDL-- 573
A A P PS I+ T ++P PQ + L P++P L G +
Sbjct: 61 ANQASPFPSPSTIAS-------TPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113
Query: 574 -----------------PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA 616
PS P+A + P ++ P + +PP S
Sbjct: 114 AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP---SVAVAESG 170
Query: 617 PKPVAAATIVSQQAEEGLT-LPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLT 675
+A I + + L +P + V P P P + V +
Sbjct: 171 SVITLSAPIAPSEPKTNLNKVPSEVVPNP---------KGTPSPPCIVSTVPYHCVTPMA 221
Query: 676 LPQDSAMTPPLPLQDTDLSSAPKPVAAAT----LVSQQAEEGLTLPQDSAMTPPLPLQDT 731
Q + P T L+ A V T L+S Q L+L ++PP L
Sbjct: 222 SIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSL--KGPVSPPAAL--- 276
Query: 732 DLSSAPKPVAAATLVSQQAEEGLTLPQD---SAMTPPLPLQDTDLS----------SAPK 778
LS+ PV + S Q G P D S + PL + SA
Sbjct: 277 SLSTQSLPV----VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALS 332
Query: 779 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 838
TI + G + P ++ PPLP ++ P VAA +V+ ++G +
Sbjct: 333 DPTVKTISVDHSSTGASYPSQRSVIPPLPSRN---EVVPATVAAFPVVAPSVDKGPSTIS 389
Query: 839 DSAMTPP-----------LPLQDTDLSSAPK-----PVAAATPVSQQAEEGLTLPQDSAM 882
+P P L S+P P+ A PVS L + +
Sbjct: 390 SITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTI 449
Query: 883 -----------TAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGE 931
T P +GP S EP + A + A P T+ VAT + V
Sbjct: 450 AAAPTTTFEVATCVSPPMSSGPISNIEPTSPAA-LVMAPVAPKEPSTQ-VATTLRIPVSP 507
Query: 932 ALGPRPAPEE-KN-------------------------------AALPTVPEPAALDQVQ 959
P P PE+ KN A L T +P L VQ
Sbjct: 508 ---PLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQ 564
Query: 960 ---QDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEA 1016
++ P + + +P ++TL ++L P P + L + ++
Sbjct: 565 AAPKNSPSFQSTSSSP-EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKT 623
Query: 1017 RAHTG-DGAKP------DSPQKETLEVENQQEGGLKP----------------------L 1047
++ G D A P +P +E+ G+ P L
Sbjct: 624 DSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSL 683
Query: 1048 AQEHGP--RSALGGAREVPDA----PPAACPEVSQARLLSPAREERGLSGKSTPEPTLPS 1101
A ++ P L VP A P A P+ + A L + KS P P+LP
Sbjct: 684 APKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE--IPKSVPSPSLPP 741
Query: 1102 A---VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ---------PEPVLGLG 1149
A T+ S++ V+S + CP + SA S + P P LG+
Sbjct: 742 AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP-LGVS 800
Query: 1150 SVEQPHEVPSVLG-----TPL------LQP------PENLAKGQPS----------TPVD 1182
Q P+ G TP+ + P PEN Q S TP
Sbjct: 801 VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
Query: 1183 RPLGPDPSA--PGTLAGAALPPLEPPAPCLC------QDPQEDSVEDEEPPGSLGLPPPQ 1234
P PSA P + G LPP E P P + + P + + P +
Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
Query: 1235 AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP-PSG 1293
A PA + + P G + +P SP P S PP PP P G
Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP-----TPPAATPPSPKG 975
Query: 1294 PQSPAGPQGLSAP 1306
+ P+G P
Sbjct: 976 GPATPSPKGAPTP 988
Score = 46.2 bits (108), Expect = 2e-04
Identities = 68/283 (24%), Positives = 93/283 (32%), Gaps = 42/283 (14%)
Query: 18 PGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG 77
P P+ + AA + GG P P + P A P P+GAS
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS------ 1033
Query: 78 GAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAART 137
P+A +G P+ LP+G + PA P G T +P
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPT--------TPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 138 ALRDQEGGHASPDP-----PPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACG 192
+GG A+P P PP +PP TPP TT A P
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPP---------AATPPSPKGGLATPPHKGAPTTPAATPP-S 1135
Query: 193 PHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWG 252
P G + + P SP G T ++P+ + +P GL PS G
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATPSPKG 1193
Query: 253 L---------SPQGSMVDERELHPAGTP--EPPSSESSLSADS 284
SP+G + TP PPS + L+ S
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/240 (25%), Positives = 83/240 (34%), Gaps = 42/240 (17%)
Query: 46 TPGPSH---LALTFL-PSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS 101
TP P L++T P K A P P+G P GAP+ P PSP P S
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGGPATPS 958
Query: 102 SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP-----PPELC 156
+ T PA P G T +P +GG A+P P PP +
Sbjct: 959 PKWAPTP---PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
Query: 157 SQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASP 216
P+ P P TPP+ T + PA P L P +P
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAA-TPPSPKGSPAATP--------------LPKGAPTTP 1060
Query: 217 SGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSS 276
+ + + G ++PS + PA P G +P P G P PP++
Sbjct: 1061 AATLPSPKGG--PATPSLKGAPTPPAATPPSPKGGPATPS----------PKGAPMPPAA 1108
>gi|163965362 nascent polypeptide-associated complex alpha subunit
isoform b [Homo sapiens]
Length = 215
Score = 243 bits (621), Expect = 8e-64
Identities = 139/219 (63%), Positives = 162/219 (73%), Gaps = 10/219 (4%)
Query: 1307 EQQEDEDSLEEDSPRA---LGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1363
E E + E++ P+ GSG SDS ES EL+EQD T Q A A EE
Sbjct: 4 EATETVPATEQELPQPQAETGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEIDEE 62
Query: 1364 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVV 1423
++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDTY+V
Sbjct: 63 PVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIV 122
Query: 1424 FGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1483
FGEAKIEDLSQQ AAAEKFKV E + + E+ P V +EE EEEEVDE G+
Sbjct: 123 FGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDETGV 176
Query: 1484 ELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1522
E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 177 EVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215
>gi|5031931 nascent polypeptide-associated complex alpha subunit
isoform b [Homo sapiens]
Length = 215
Score = 243 bits (621), Expect = 8e-64
Identities = 139/219 (63%), Positives = 162/219 (73%), Gaps = 10/219 (4%)
Query: 1307 EQQEDEDSLEEDSPRA---LGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1363
E E + E++ P+ GSG SDS ES EL+EQD T Q A A EE
Sbjct: 4 EATETVPATEQELPQPQAETGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEIDEE 62
Query: 1364 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVV 1423
++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDTY+V
Sbjct: 63 PVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIV 122
Query: 1424 FGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1483
FGEAKIEDLSQQ AAAEKFKV E + + E+ P V +EE EEEEVDE G+
Sbjct: 123 FGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDETGV 176
Query: 1484 ELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1522
E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 177 EVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215
>gi|163965364 nascent polypeptide-associated complex alpha subunit
isoform b [Homo sapiens]
Length = 215
Score = 243 bits (621), Expect = 8e-64
Identities = 139/219 (63%), Positives = 162/219 (73%), Gaps = 10/219 (4%)
Query: 1307 EQQEDEDSLEEDSPRA---LGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1363
E E + E++ P+ GSG SDS ES EL+EQD T Q A A EE
Sbjct: 4 EATETVPATEQELPQPQAETGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEIDEE 62
Query: 1364 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVV 1423
++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDTY+V
Sbjct: 63 PVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIV 122
Query: 1424 FGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1483
FGEAKIEDLSQQ AAAEKFKV E + + E+ P V +EE EEEEVDE G+
Sbjct: 123 FGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDETGV 176
Query: 1484 ELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1522
E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 177 EVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215
>gi|40548328 nascent-polypeptide-associated complex alpha
polypeptide-like [Homo sapiens]
Length = 215
Score = 222 bits (566), Expect = 2e-57
Identities = 128/219 (58%), Positives = 157/219 (71%), Gaps = 10/219 (4%)
Query: 1307 EQQEDEDSLEEDSPRA---LGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1363
E E + E++ P++ GSG SDS GES ++EQD T + A A EE
Sbjct: 4 EATETVPATEQELPQSQAETGSGTASDS-GESVPGIEEQDSTQTTTQKAWLVAAAEIDEE 62
Query: 1364 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVV 1423
+ KAKQSRSEK+ARKAMSKLGL Q+ GVTR+TI KSKNILFVI K DV+KSPASD Y+V
Sbjct: 63 PVGKAKQSRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYIV 122
Query: 1424 FGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1483
FGEAKI+DLSQQ AAAEKF+V E + E+ P V +EE EEEEVDE G+
Sbjct: 123 FGEAKIQDLSQQAQLAAAEKFRVQGEAVGNIQENTQTPTV------QEESEEEEVDETGV 176
Query: 1484 ELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1522
E++D++LVM+QANVSRAKAVRAL++N +DIVNAIMELT+
Sbjct: 177 EVKDVKLVMSQANVSRAKAVRALKNNSNDIVNAIMELTV 215
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 107 bits (268), Expect = 7e-23
Identities = 201/825 (24%), Positives = 296/825 (35%), Gaps = 131/825 (15%)
Query: 597 PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSA 656
P+ +T P + L KP+ A + Q E L P + M P +++ LS
Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGV---QLEPQLEAPLNEEMPLLPPPEESPLSPP 452
Query: 657 PK-----PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK-----PVAAATLV 706
P+ P A+ +S EE P A+ PL+++ LS P+ P ++
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512
Query: 707 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL 766
S E L+ P++S PP P +T LS P+ A+ +S EE S ++PP
Sbjct: 513 SPLEESPLSPPEES---PPSPALETPLSPPPE----ASPLSPPFEE-------SPLSPP- 557
Query: 767 PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL-------PLQDTDLSSAPKP 819
+L ++P P A+ + P++S M+PP P +++ LS P P
Sbjct: 558 ---PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLS--PPP 612
Query: 820 VAAATIVSQQAEEGLTLPQDSAMTPPL-------PLQDTDLSSAP-----KPVAAATPVS 867
+ +A P+DS M+PP P + + LS P P +P+S
Sbjct: 613 EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 672
Query: 868 QQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQ- 926
EE T P A P +D+ PTS P + A+P + P+ + +
Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDS-PTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEE 731
Query: 927 -QEVGEALGPR--PAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 983
Q + GP P PEE + + P EP Q ++ P E A E+ +
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLS-PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790
Query: 984 GMEALSL---PEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQ- 1039
E L PE + + LS E CL SPQ E + Q
Sbjct: 791 QAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL-------------SPQPEESHLSPQS 837
Query: 1040 QEGGLKPLAQEHG-----PRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKST 1094
+E L P +E + L E P P CP + L P E
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 1095 PEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAP---TSQQPEPVLGLGSV 1151
P + P + P S G S + P P P T+ P + LG +
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 1152 EQPH--------EVP---SVLGTPLLQPPE-NLAKGQPSTPVDRPLGPDPSAPGTLAGAA 1199
E P E P +L TP+ PPE N +P P+ P +PG+ G A
Sbjct: 958 EYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILP-----PSPGSPVGPA 1012
Query: 1200 LPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSL 1259
P L P P C + S+ + P S PP +V P+ G V +
Sbjct: 1013 SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP------ALPLSVPSPLSPI--GKVVGV 1064
Query: 1260 SPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQG-LSAPEQQEDEDSLEED 1318
S + L + + P C PS P G LS P
Sbjct: 1065 SDEAELHEMETEKVSE--------PECPALEPSATSPLPSPMGDLSCP------------ 1104
Query: 1319 SPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1363
+P + GE +A LD D AP + P Q P + E
Sbjct: 1105 APSPAPALDDFSGLGEDTAPLDGID--APGSQPEPGQTPGSLASE 1147
Score = 75.5 bits (184), Expect = 4e-13
Identities = 212/900 (23%), Positives = 312/900 (34%), Gaps = 140/900 (15%)
Query: 503 TPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSP 562
+P + EE+ + E+ P+ S S E+LPT + L P
Sbjct: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 563 QNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 622
++ + P P A+ P + P++S ++PP + S P
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP---PEASRLSPP----- 629
Query: 623 ATIVSQQAEEGLTLPQDSVMTPP---LPLQDTELSSAPKPVAAATLVSQQAEEG-LTLPQ 678
P+DS M+PP P+ S P+ + +S EE L+ P
Sbjct: 630 --------------PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
Query: 679 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 738
+ + T P P + + LS P P + T + P+DS M+ LPL+++ L P+
Sbjct: 676 EESPTSP-PPEASRLS--PPPEDSPTSPPPEDSPASPPPEDSLMS--LPLEESPLLPLPE 730
Query: 739 -----PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATI-----VSQ 788
P + +S + EE P+ ++ LS P+ + +S
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790
Query: 789 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ-DSAMTPPLP 847
QAE PQ + ++ LS PV +S Q EE PQ + P P
Sbjct: 791 QAEGPHLSPQPEELHLSPQTEEPHLS----PVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 848 LQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQT 907
+++ LS P P+S + E+ P LPL P P +
Sbjct: 847 -EESHLS----PELEKPPLSPRPEKPPEEPGQCPAPEELPL-------FPPPGEPSLSPL 894
Query: 908 LQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVP--EPAALDQVQQDDPQP 965
L A PG P++ P PEE LP P EP+ Q+ DP P
Sbjct: 895 LGEPALSEPGEPPLS--------------PLPEE----LPLSPSGEPSLSPQLMPPDPLP 936
Query: 966 AAEAGTPWAAQEDADSTLG-----MEALSLPEPASGAGEEIAEALSRPGREACLEARAHT 1020
+ AA A S LG A +P S I E P EA
Sbjct: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
Query: 1021 GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPR--SALGGAREVP-DAPPAACP----E 1073
P SP G P+ E P S L VP ++PP+ C
Sbjct: 997 PPMILPPSP--------GSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALP 1048
Query: 1074 VSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSL-----DRGCP 1128
+S LSP + G+S E L + S CP A S L D CP
Sbjct: 1049 LSVPSPLSPIGKVVGVS----DEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCP 1104
Query: 1129 -DAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGP 1187
+PAP S E L ++ P P Q P +LA +PV L P
Sbjct: 1105 APSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP-----GQTPGSLASELKGSPV--LLDP 1157
Query: 1188 DPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGT 1247
+ AP T P+E C Q E++E P + P P ++ + +
Sbjct: 1158 EELAPVT-------PMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIK---SDIVNE 1207
Query: 1248 TQPLGTGPRVSLSPHS-PLL-SPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQG--- 1302
L G + P S PLL SP + + L + S SPA +G
Sbjct: 1208 ISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGV---------STDVSPARDEGSLR 1258
Query: 1303 LSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPA-QAPAGGS 1361
L E +DSL D+ A+ G+ G + I ++ P + P GG+
Sbjct: 1259 LCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGA 1318
Score = 71.6 bits (174), Expect = 5e-12
Identities = 141/522 (27%), Positives = 179/522 (34%), Gaps = 110/522 (21%)
Query: 877 PQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQ-------EV 929
P S + P P DT PT P+ L VA Q + G +P Q +
Sbjct: 367 PVCSRFSPPEP-GDT-PTDEPDALYVACQG--QPKGGHVTSMQPKEPGPLQCEAKPLGKA 422
Query: 930 GEALGPR-PAPEEKNAALPTVPEPAALDQVQQDDP-QPAAEAGTPWAAQEDADSTLGMEA 987
G L P+ AP + L PE + L ++ P P EA E+ ++ EA
Sbjct: 423 GVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA 482
Query: 988 LSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPL 1047
L L P + LS P E+ P SP E+ +E L P
Sbjct: 483 LHLSRPLEES------PLSPPPEES-------------PLSPPPESSPFSPLEESPLSP- 522
Query: 1048 AQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEA 1107
+E P AL E P +PP PE S LSP EE LS P LP++ EA
Sbjct: 523 PEESPPSPAL----ETPLSPP---PEASP---LSPPFEESPLS---PPPEELPTSPPPEA 569
Query: 1108 S-LDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLL 1166
S L PE S P +P P +P S PE E+ P +PL
Sbjct: 570 SRLSPPPEES-----------PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618
Query: 1167 QPPENLAKGQPSTPVDRPLGPDPS-------------APGTLAGAALPPLE--------- 1204
PPE P P D P+ P P +P + PP E
Sbjct: 619 PPPEASRLSPP--PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE 676
Query: 1205 ------PPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQ--------P 1250
PP P EDS P S PPP+ + S P
Sbjct: 677 ESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
Query: 1251 LGTGPRVSLSPHSPLLSPKV----ASMDAKDLALQILP--PCQVPPPSGPQ-SP--AGPQ 1301
GP +S P P LSP+ S A++ L P PC P P SP GP
Sbjct: 737 RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPH 796
Query: 1302 GLSAPEQ-----QEDEDSLEEDSPRALGSGQHSDSHGESSAE 1338
PE+ Q +E L S Q +SH +E
Sbjct: 797 LSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838
Score = 48.9 bits (115), Expect = 4e-05
Identities = 153/683 (22%), Positives = 232/683 (33%), Gaps = 101/683 (14%)
Query: 607 PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLV 666
P T+ + PKP ++ + +GL + Q S P P Q + P VA V
Sbjct: 3761 PGVQTNQALGPKPQG---LMPPSSHQGLLVQQLS----PQPPQGPQGMLGPAQVA----V 3809
Query: 667 SQQAEEGLTLPQDS----AMTPPLPLQDTDLSSAPKPVAAATLVS-QQAEEGLTLPQDSA 721
QQ G PQ MT L L+ + + LV+ QQ ++ Q +
Sbjct: 3810 LQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGS 3869
Query: 722 MTPPLPLQDTDLSSAPKPVAAATLVS--QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 779
M LQ + +S + +P +A + QQ ++ L Q L Q +
Sbjct: 3870 MAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ----LQQQQQQQLQQQQQ 3925
Query: 780 VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 839
+ + QQ ++ L Q L Q L + QQ ++ L Q
Sbjct: 3926 LQQQQLQQQQQQQQLQQQQQQQ----LQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981
Query: 840 SAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ----DSAMTAPLPLQDTGPTS 895
+ P Q ++ P A P+ + G P P + T
Sbjct: 3982 RTLLSPQQQQQQQVALGPG--MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
Query: 896 GPE-----PLAVAT-PQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTV 949
GP PLA+ T P+++ E G E +++ + P+P P+ + L
Sbjct: 4040 GPSTHQGGPLAIGTTPESMATEPG-----EVKPSLSGDSQLLLVQPQPQPQPSSLQLQP- 4093
Query: 950 PEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLP----EPASGAGEE---IA 1002
P L QQ AG Q + S+ EA S+P +P+ G++ +
Sbjct: 4094 --PLRLPGQQQQQVSLLHTAGGGSHGQLGSGSS--SEASSVPHLLAQPSVSLGDQPGSMT 4149
Query: 1003 EALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGARE 1062
+ L P ++ LE G +P P + G+ P + R+ L G
Sbjct: 4150 QNLLGP-QQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQL--RAQLQGVLA 4206
Query: 1063 VPDAPPAACPEVSQA--RLLSPAREERGLSGKSTP---EP-----TLPSAVATEASLDSC 1112
P+ Q LL + ++ + + TP EP L + + L
Sbjct: 4207 KNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF 4266
Query: 1113 PESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENL 1172
P G + L G P P P P L G V P V TP P+
Sbjct: 4267 PGPQTGPLQELGAG----PRPQGPPRLPAPPGALSTGPVLGP-----VHPTPPPSSPQ-- 4315
Query: 1173 AKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPP 1232
+P P P P P A LPP P P PQ ++E P
Sbjct: 4316 ---EPKRPSQLP-SPSSQLP---TEAQLPPTHPGTP----KPQGPTLE-----------P 4353
Query: 1233 PQAGVQPAAAAVSGTTQPLGTGP 1255
P V PAAA ++ T G GP
Sbjct: 4354 PPGRVSPAAAQLADTLFSKGLGP 4376
Score = 47.0 bits (110), Expect = 1e-04
Identities = 131/590 (22%), Positives = 191/590 (32%), Gaps = 70/590 (11%)
Query: 606 LPLQDTDLSSAPKPVAAATIV--SQQAEEGLTLPQDSVMTPPL-----PLQDTELSSAPK 658
+P Q L S P P AA TI S GL+ D + PP P EL
Sbjct: 2106 IPPQPGALGSPP-PAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
Query: 659 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT---LVSQQAEEGLT 715
P A + SQ + L + P P P P A ++ + G
Sbjct: 2165 PQVPAQVPSQ---DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221
Query: 716 LPQDSAMTPP-------------LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAM 762
P + TPP L + L + P + + +E L+ P
Sbjct: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGES 2281
Query: 763 TPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 822
L ++ +L ++ + + P L L+ D+ AP A
Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFVDS------PSSGTHLGGLELKTPDVFKAPLTPRA 2335
Query: 823 ATIVSQQAEEGLTL--PQDSAMTPPLPLQDTDL-------SSAPKPVAAATPVSQQAEEG 873
+ + Q GL P + P P D+ +P P E
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395
Query: 874 LTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEAL 933
LP S + P P S + TP+ L AEA C PV Q +
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFC---PSPVTPRFQSPDPYSR 2452
Query: 934 GP-RPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPE 992
P RP + A L P P P+ A +AG+ A ++LG
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRP--------QPPEVAFKAGSL------AHTSLGAGGFPAAL 2498
Query: 993 PASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHG 1052
PA AGE A+ S G+ TG SP + T + E LKP + G
Sbjct: 2499 PAGPAGELHAKVPS--GQPPNFVRSPGTGAFVGTPSPMRFTFP-QAVGEPSLKPPVPQPG 2555
Query: 1053 PRSALGGAREVPDAPPAACPEVSQARLLS----PAREERGLSGKSTPEPTLPSAVATEAS 1108
G P P+ + + + P+ G S ST E S + +
Sbjct: 2556 LPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV 2615
Query: 1109 LDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVP 1158
L P + G++ L G TS P ++ +P G+GS E+P
Sbjct: 2616 LP--PPAPDGSLPYLSHGASQRSGITS-PVEKREDPGTGMGSSLATAELP 2662
Score = 45.4 bits (106), Expect = 4e-04
Identities = 192/874 (21%), Positives = 301/874 (34%), Gaps = 149/874 (17%)
Query: 574 PSGRKPVAAATIVPRQAKEDLTLPQ-----DSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 628
P R P AA PR A LP+ + P P Q T + +P AA +
Sbjct: 3096 PEERPPPAADASEPRLAS---VLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGL 3152
Query: 629 QAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 688
+ G ++ + +DT + + P + T +++A G T + + P PL
Sbjct: 3153 GLKPGQSM---------MGSRDTRMGTGPFSSSGHT--AEKASFGATGGPPAHLLTPSPL 3201
Query: 689 QDTDLSSAPKPVAAATLVSQQAEEG-LTLPQDSAMT-PPLPLQDTDLSSAPKPVAAATLV 746
P ++ L + E G LTLP A + L ++ L ++ P+ L+
Sbjct: 3202 SG--------PGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLL 3253
Query: 747 SQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAATIVSQQA-------EEGL 794
+ +E Q SA P Q L SAP P A ++ + + ++ L
Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQL 3313
Query: 795 TLPQDSAMTP--PLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP-QDSAMTPPLPLQDT 851
+L A P P PL T + A ++ + +G L Q +P Q +
Sbjct: 3314 SLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSS 3373
Query: 852 DLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPE---PLAVATPQTL 908
+ KP+ P + L + Q A + P D + + P+A A L
Sbjct: 3374 QPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSF-FPDTDLDKFAAEDIIDPIAKAKMVAL 3432
Query: 909 --------QAEAGCAPGT--EPVATMAQQEVGEALGPRP---------APEEKNAALPTV 949
Q G APG + V+ +AQ+ G GP + +E++A P+
Sbjct: 3433 KGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSG---GPSSDLQNHVAAGSGQERSAGDPSQ 3489
Query: 950 PEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPG 1009
P P +P A+ A Q + L L E+I + R
Sbjct: 3490 PRP---------NPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIG--VHRKS 3538
Query: 1010 REA-CLEARAHTGDGAKPDSPQKETLEVENQQEGGL-KPLAQ------EHGPRSA--LGG 1059
R+A C + R G + E L++ +Q+ + K L Q EH A
Sbjct: 3539 RKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNK 3598
Query: 1060 AREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA 1119
++ + S LSP++ R L+ LP + L P+ G
Sbjct: 3599 QQQQQQQQQQQQQQHSAVLALSPSQSPRLLT-------KLPGQLLPGHGLQP-PQGPPGG 3650
Query: 1120 VSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPST 1179
+ R P A P P L +Q + S L P G +
Sbjct: 3651 QAGGLRLTPGGMALPGQPGG----PFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLAL 3706
Query: 1180 PVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQP 1239
R LGPD L L+ L Q Q+ + ++ LG Q +Q
Sbjct: 3707 ---RSLGPD----SRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLG----QVAIQQ 3755
Query: 1240 AAAAVSG--TTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1297
G T Q LG P+ + P S + L +Q L P PP GPQ
Sbjct: 3756 QQQQGPGVQTNQALGPKPQGLMPPSSH-----------QGLLVQQLSP---QPPQGPQGM 3801
Query: 1298 AGPQGLSAPEQQEDEDSLEEDSPRALG-SGQHSDSHGESSAELDEQDILAPQTVQCPAQA 1356
GP ++ +QQ P ALG G H S L + AQ
Sbjct: 3802 LGPAQVAVLQQQH---------PGALGPQGPHRQVLMTQSRVLSSPQL---------AQQ 3843
Query: 1357 PAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQ 1390
G + A+Q + +++ ++ S GL +Q
Sbjct: 3844 GQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQ 3877
Score = 45.1 bits (105), Expect = 5e-04
Identities = 78/294 (26%), Positives = 107/294 (36%), Gaps = 46/294 (15%)
Query: 45 LTPGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS--- 101
L+P P L +P +P PQ EG P P E SP LS
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEG----------PHLSPQPEELHLSPQTEEPHLSPVP 819
Query: 102 SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQ-EGGHASPDP--PPELCSQ 158
+ + P + L P+ EE C LSPR + L + E SP P PPE Q
Sbjct: 820 EEPCLSPQPEESHLSPQ---SEEPC---LSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873
Query: 159 GDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSG 218
P P+ F PP P+ + PA G+ S L +EL SP PS
Sbjct: 874 ------CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLS--PLPEELPLSPSGEPSL 925
Query: 219 SYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSES 278
S D S ++ AP LSP G + E G +P S +
Sbjct: 926 SPQLMPPDPLPPPLSPIITAAAPP---------ALSPLGEL--EYPFGAKGDSDPESPLA 974
Query: 279 SLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPE 332
+ ++ S E + D +P+ P L P GS + + + PL P+
Sbjct: 975 APILETPISPPPEANCTD-----PEPVPPMILPPSPGSPVGPASPILMEPLPPQ 1023
Score = 43.5 bits (101), Expect = 0.002
Identities = 136/604 (22%), Positives = 196/604 (32%), Gaps = 56/604 (9%)
Query: 727 PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 786
P T+ + PKP L+ + +GL + Q S P P Q P VA V
Sbjct: 3761 PGVQTNQALGPKPQG---LMPPSSHQGLLVQQLS----PQPPQGPQGMLGPAQVA----V 3809
Query: 787 SQQAEEGLTLPQDS----AMTPPLPLQDTDLSSAPKPVAAATIVS-QQAEEGLTLPQDSA 841
QQ G PQ MT L L+ + + +V+ QQ ++ Q +
Sbjct: 3810 LQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGS 3869
Query: 842 MTPPLPLQDTDLSSAPKPVAAATPVSQ----QAEEGLTLPQDSAMTAPLPLQDTGPTSGP 897
M LQ + +S + +P +A P+ Q ++ L Q LQ
Sbjct: 3870 MAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQ 3929
Query: 898 EPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQ 957
+ Q LQ + + QQ+ + + +++ L L
Sbjct: 3930 QLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQ--SRTLLSP 3987
Query: 958 VQQDDPQPAAEAGTPWAAQEDADS--TLGMEALSLPEPASGAGEEIAEALSRPGREACLE 1015
QQ Q A G P + S LG L G+E EA
Sbjct: 3988 QQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLL-------TGKEQNTVDPAVSSEATEG 4040
Query: 1016 ARAHTGD----GAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDA--PPA 1069
H G G P+S E EV+ G + L + P+ + P P
Sbjct: 4041 PSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQ 4100
Query: 1070 ACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEA-SLDSCPESSVGAVSSLDRGCP 1128
+VS + SG S+ ++P +A + SL P S + +
Sbjct: 4101 QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPML 4160
Query: 1129 DAPAPTSA-PTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGP 1187
+ P + P +P PVL G + +G Q LAK P R L P
Sbjct: 4161 ERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKN----PQLRHLSP 4216
Query: 1188 DPSAPGTLAGAALPPLEPPAPCLCQDP--QEDSVEDEEPPGSLGLPPPQAGVQPAAAAVS 1245
L + + + Q P QE + G LG P G +
Sbjct: 4217 QQQQQ--LQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFP---GPQT 4271
Query: 1246 GTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSA 1305
G Q LG GPR P P A A + P PPPS PQ P P L +
Sbjct: 4272 GPLQELGAGPRPQGPPRLP------APPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS 4325
Query: 1306 PEQQ 1309
P Q
Sbjct: 4326 PSSQ 4329
Score = 41.6 bits (96), Expect = 0.006
Identities = 121/517 (23%), Positives = 163/517 (31%), Gaps = 129/517 (24%)
Query: 806 LPLQDTDLSSAPKPVAAATIV--SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863
+P Q L S P P AA TI S GL+ D + PP S P P
Sbjct: 2106 IPPQPGALGSPP-PAAAPTIFIGSPTTPAGLSTSADGFLKPPA-------GSVPGP---- 2153
Query: 864 TPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVAT 923
E L LP + A +P QD P +A L+ AP T P
Sbjct: 2154 ---DSPGELFLKLPPQ--VPAQVPSQD--------PFGLAPAYPLEPRFPTAPPTYP--- 2197
Query: 924 MAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 983
P P+P A P + + Q + GTP D L
Sbjct: 2198 -----------PYPSPTGAPAQPPMLGASSRPGAGQPGEFH-TTPPGTPRHQPSTPDPFL 2245
Query: 984 -----GMEALSLPE-PASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVE 1037
++ L++PE P G G+ LS P P ++ LEV+
Sbjct: 2246 KPRCPSLDNLAVPESPGVGGGKASEPLLSPP-----------------PFGESRKALEVK 2288
Query: 1038 NQQEGGLKP------LAQEHGPRSA--LGGAR-EVPDAPPAAC-PEVSQARLLSPAREER 1087
++ G P L P S LGG + PD A P SQ SP
Sbjct: 2289 KEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSP----- 2343
Query: 1088 GLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLG 1147
GL G EP A+A P+P S P +P
Sbjct: 2344 GL-GLRPQEPPPAQALA--------------------------PSPPSHPDIFRP----- 2371
Query: 1148 LGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALP--PLEP 1205
GS P+ P + P PPE+ P + P P++P + + + P P
Sbjct: 2372 -GSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPL 2430
Query: 1206 PAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPL 1265
A C P + +P PP + + A PL PR P P
Sbjct: 2431 SAEAFCPSPVTPRFQSPDP---YSRPPSRPQSRDPFA-------PLHKPPR----PQPPE 2476
Query: 1266 LSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQG 1302
++ K S+ L P P+G P G
Sbjct: 2477 VAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSG 2513
Score = 40.8 bits (94), Expect = 0.010
Identities = 87/375 (23%), Positives = 133/375 (35%), Gaps = 54/375 (14%)
Query: 891 TGPTSGPEPLAVATPQTLQAEA--GCAP----GTEPVATMAQQEVGEALGPRPAPEEKN- 943
+ P + P L P ++Q + G P G P + ++ AL R E K+
Sbjct: 4617 SNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERAL--RDTSEVKSL 4674
Query: 944 ---AALPTVPEPAALD-QVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGE 999
AALPT P D +++ D+ + ++ P ++ E S LG EA P SG E
Sbjct: 4675 DLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPE---SILGEEAPRFPHLGSGRWE 4731
Query: 1000 EIAEALS-----------------RPGREACLEARA-------HTGDGAKPDSPQKETLE 1035
+ ALS +P LE G G++ +
Sbjct: 4732 QEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAA 4791
Query: 1036 VENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP 1095
G + +A+ + P++P A E + P +E+GL GKS P
Sbjct: 4792 AAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKS-P 4850
Query: 1096 EPTLPSAVATEASLDSCP-ESSVGAVSSLDRGCPDAPAPT----SAPTSQQPEPVLGLGS 1150
+ +A L +S + +S L + P PT + S L
Sbjct: 4851 DTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP 4910
Query: 1151 VEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCL 1210
E+P PS L PP P+ P+ +P P L A+ P P P
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPL-----AEPPVPSPLPLASSPESARPKP-R 4964
Query: 1211 CQDPQEDSVEDEEPP 1225
+ P+E ED PP
Sbjct: 4965 ARPPEEG--EDSRPP 4977
Score = 36.2 bits (82), Expect = 0.25
Identities = 159/773 (20%), Positives = 239/773 (30%), Gaps = 152/773 (19%)
Query: 686 LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 745
L L+ D+ AP A+ + Q GL PQ+ PP S P +
Sbjct: 2319 LELKTPDVFKAPLTPRASQVEPQSPGLGLR-PQEP---PPAQALAPSPPSHPDIFRPGSY 2374
Query: 746 VSQQAEEGLTL------PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 799
A+ LT P+ PP L S P A+ SQ + + P+
Sbjct: 2375 TDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVP-----ASPQSQSSSQSPLTPRP 2429
Query: 800 SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL------PLQDTDL 853
+ P T +P P + Q + L + PP L T L
Sbjct: 2430 LSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSL 2489
Query: 854 SSAPKPVAAATPVSQQAEEGLTLPQDSA------------MTAPLPLQDTGPTSGPEPL- 900
+ P AA P E +P + P P++ T P + EP
Sbjct: 2490 GAGGFP--AALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSL 2547
Query: 901 -------AVATPQTLQAEAGCAPG-------TEPVATMAQQEVGEALGPRPAPEEKNAAL 946
+ P + + G P VAT G LGP ++ L
Sbjct: 2548 KPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGL 2607
Query: 947 PTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD-STLGMEALSLPEPASGAGEEIAEAL 1005
+ P+ L P PA + P+ + + S + +P +G G +A A
Sbjct: 2608 SPLRPPSVL-------PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAE 2660
Query: 1006 SRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPD 1065
++ + + T + ++ E+ +Q+ L QE +A GA P
Sbjct: 2661 LPGTQDPGMSGLSQTE--LEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG 2718
Query: 1066 A------------------PPAACPEVSQARLLSPAREERGLSGK----STPEPTLPSAV 1103
+ P A + S L P++ + G S + P
Sbjct: 2719 SWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPP 2778
Query: 1104 ATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPV-----------------L 1146
AT +S+D VG + + AP P S P QQ + +
Sbjct: 2779 ATPSSMDVNSRQLVGGSQAFYQR---APYPGSLPLQQQQQQLWQQQQATAATSMRFAMSA 2835
Query: 1147 GLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDP------------SAPGT 1194
S P LG+PL L P PV P GP GT
Sbjct: 2836 RFPSTPGPELGRQALGSPLAGISTRLPG--PGEPVPGPAGPAQFIELRHNVQKGLGPGGT 2893
Query: 1195 LAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPA---------AAAVS 1245
PP P + +DP + E GLPP + PA
Sbjct: 2894 PFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTK 2953
Query: 1246 GTTQPLGTGPRVSLSPHSPLLS-PKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLS 1304
G T P G V+ P S L P +++A L PC + P
Sbjct: 2954 GPTLPTGL-ELVNRPPSSTELGRPNPLALEAGKL------PC--------EDPELDDDFD 2998
Query: 1305 APEQQEDEDSLE-----------EDSPRALGSGQHSDSHGESSAELDEQDILA 1346
A + ED++ L +D L + + +D H + DE D+LA
Sbjct: 2999 AHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLA 3051
Score = 35.8 bits (81), Expect = 0.32
Identities = 164/746 (21%), Positives = 240/746 (32%), Gaps = 114/746 (15%)
Query: 560 DSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKP 619
DSP + GGL+L + V A + PR ++ + PQ +P L L+ + P
Sbjct: 2308 DSPSSGTHLGGLELKT--PDVFKAPLTPRASQVE---PQ----SPGLGLRPQE-----PP 2353
Query: 620 VAAATIVSQQAEEGLTLP---QDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTL 676
A A S + + P D PPL T P P + L + +L
Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPL----TPRPQPPPPESCCALPPR------SL 2403
Query: 677 PQDSAMTPPLPLQDTDLSSAP---KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDL 733
P D P Q S +P +P++A P + P P
Sbjct: 2404 PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPF 2463
Query: 734 SSA-----PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDL---SSAP----KPVA 781
+ P+P A A L A P P + S P +
Sbjct: 2464 APLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPG 2523
Query: 782 AATIVSQQAEEGLTLPQ---DSAMTPPLPL------QDTDLSSAPKP-VAAATIVSQQAE 831
V + T PQ + ++ PP+P + P P + +
Sbjct: 2524 TGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVA 2583
Query: 832 EGLTLPQDSAMTPPL----------PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSA 881
G P S + P PL+ + P P + +S A Q S
Sbjct: 2584 TGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGAS------QRSG 2637
Query: 882 MTAPLPLQDTGPTSGPEPLAVAT-PQTLQAEAGCAPGTEPVATMAQQEVGEAL------- 933
+T+P+ ++ T LA A P T TE +Q + E L
Sbjct: 2638 ITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQR 2697
Query: 934 -GPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAE----AGTPWAAQEDADSTLGMEAL 988
R E AA V P + + PA E TP+A +D S +G+
Sbjct: 2698 NTLRQEKETAAAAAGAVGPPGSWGA---EPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPS 2754
Query: 989 SLPEPASGAGE-EIAEALSRPGREAC-----LEARAHTGDGAK--PDSPQKETLEVENQQ 1040
L P G G + LSRP A + +R G +P +L ++ QQ
Sbjct: 2755 KLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQ 2814
Query: 1041 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSP-AREERGLSGKSTPEPTL 1099
+ + + P P PE+ + L SP A L G P P
Sbjct: 2815 QQLWQQQQATAATSMRFAMSARFPSTPG---PELGRQALGSPLAGISTRLPGPGEPVPG- 2870
Query: 1100 PSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ-----PEPVLGLGSVEQP 1154
P+ A L + +G + G P P S+ PE + GL P
Sbjct: 2871 PAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLP 2930
Query: 1155 HEVPSVLGTPLLQ---PPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLC 1211
+ PS P L P KG P+ P L P + T G P C
Sbjct: 2931 PQKPSAPPAPELNNSLHPTPHTKG-PTLPTGLELVNRPPS-STELGRPNPLALEAGKLPC 2988
Query: 1212 QDPQED-------SVEDEEPPGSLGL 1230
+DP+ D ++ED+E LGL
Sbjct: 2989 EDPELDDDFDAHKALEDDEELAHLGL 3014
Score = 35.0 bits (79), Expect = 0.55
Identities = 36/128 (28%), Positives = 51/128 (39%), Gaps = 18/128 (14%)
Query: 132 PRAARTALRDQEGGHASPDPPP---ELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALL 188
P ++ LR G A P P +L ++ +LS P PP PPS K +
Sbjct: 4584 PVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVT 4643
Query: 189 PA--CGPH----GDARDSEAELRD-------ELLDSPPASPSGSY--ITADGDSWASSPS 233
P+ G H ARDSE LRD +LL + P P + + D + SP
Sbjct: 4644 PSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPD 4703
Query: 234 CSLSLLAP 241
+ +P
Sbjct: 4704 SIVPASSP 4711
Score = 34.7 bits (78), Expect = 0.72
Identities = 46/174 (26%), Positives = 63/174 (36%), Gaps = 16/174 (9%)
Query: 112 PATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPD 171
P P I +G T A LS +A L+ G PD P EL + VP+ P D
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLST-SADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQD 2175
Query: 172 SFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDS---PPASPSGSYITADGDSW 228
F P+ P + + P P + + A + +L + P A G + T +
Sbjct: 2176 PFGLAPAYPLEPRFPTAPPTYPPYPS-PTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTP 2234
Query: 229 ASSPSCSLSLLAP----AEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSES 278
PS L P + L P G+ G E L P PP ES
Sbjct: 2235 RHQPSTPDPFLKPRCPSLDNLAVPESPGVG--GGKASEPLLSP-----PPFGES 2281
Score = 32.3 bits (72), Expect = 3.6
Identities = 69/269 (25%), Positives = 96/269 (35%), Gaps = 57/269 (21%)
Query: 44 ALTPGPSHLALTFLP-------SKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPML- 95
AL P P F P ++P P+P+ P S A P PS
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ-------PPPPESCCALPPRSLPSDPFS 2409
Query: 96 -LPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP--- 151
+P SQ+ S+++PL PR + E C + ++PR SPDP
Sbjct: 2410 RVPASPQSQS-SSQSPLT----PRPLSAEAFCPSPVTPR------------FQSPDPYSR 2452
Query: 152 PPELCSQGD----LSVPSPPPDPDSFFTPPSTP-TKTTYALLPACGPHGDARDSEAELRD 206
PP D L P P P+ F S T PA P G A + A++
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512
Query: 207 ELLDSPPASP-SGSYITADGDSWASSPSC----SLSLLAPAEGLDFPSGWGL-------- 253
+ SP +G+++ + P SL P GL P G
Sbjct: 2513 GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTL 2572
Query: 254 -SPQGS--MVDERELHPAGTPEPPSSESS 279
PQ + V HP+G+P PSS S+
Sbjct: 2573 GKPQSTNYTVATGNFHPSGSPLGPSSGST 2601
Score = 31.2 bits (69), Expect = 8.0
Identities = 83/340 (24%), Positives = 111/340 (32%), Gaps = 37/340 (10%)
Query: 13 PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72
PEA R P + S + E L P L+ P + P PE +
Sbjct: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626
Query: 73 DAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSP 132
P +P + P E SP PE +S +PLP R+ E P
Sbjct: 627 SPPPEDSPMS-PPPEESPMSPP--PE------VSRLSPLPVV--SRLSPPPEESPLSPPP 675
Query: 133 RAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFT-----PPSTPTKTTYAL 187
+ T+ E SP P S P+ PP DS + P P L
Sbjct: 676 EESPTS-PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
Query: 188 LPAC-GPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLD 246
P GPH R E L + P SP A+ + P P E
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPR-PEEPHLSPQ-----AEEPHLSPQPEEPCLCAVPEEPHL 788
Query: 247 FPSGWG--LSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDP 304
P G LSPQ ELH + E P S +E H L + +P
Sbjct: 789 SPQAEGPHLSPQ-----PEELHLSPQTEEPHLSPVPEEPCLSPQPEESH---LSPQSEEP 840
Query: 305 MIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDP 344
+ P + L ++E ++P PE+ EE P P
Sbjct: 841 CLSPR--PEESHLSPELEKPPLSP-RPEKPPEEPGQCPAP 877
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 99.8 bits (247), Expect = 2e-20
Identities = 209/802 (26%), Positives = 275/802 (34%), Gaps = 134/802 (16%)
Query: 600 SAMTPPLPLQDTDLS-SAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPK 658
S T P PL L SA + VA L+ + P P P
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-------GTPS 173
Query: 659 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQ 718
P A + E GL P SA P P + S VS +E T P
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPRKS-----------VSSASEHSTTEPS 221
Query: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778
+A P ++ ++AT +S A G + TP P S PK
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----PSARGTPRAPAHP----SQPK 273
Query: 779 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS----------APKPVAAATIVSQ 828
P + Q +T P+ A PL + L++ P P AAT +
Sbjct: 274 PKGLQALRPPQ----VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA 329
Query: 829 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATPVSQQAEEGLTLPQDSAMTA 884
TLP + PLPL S+ P P ATP S QA +T P M A
Sbjct: 330 ------TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS-QAPPSMTTP---PMQA 379
Query: 885 PLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNA 944
P LQ P P L T +LQA P+A ++ + +LG P + ++
Sbjct: 380 PPSLQTIPPIQVPHSL---TSPSLQAP------PSPLA-LSSLQATTSLG-SPTLQATHS 428
Query: 945 ALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLP--EPASGAGEEIA 1002
L P Q Q P+ A TP DS LSLP P +
Sbjct: 429 FLTMSPR-----QTQASLTSPSRPASTP------PDSPPLQAPLSLPASPPLQTSLSPAV 477
Query: 1003 EALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGARE 1062
LS P L+A + + P +P + + + L P + + P S E
Sbjct: 478 SPLSSPLTIHPLQALSSLASHS-PQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
Query: 1063 -VPD---------APPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSC 1112
+P + P P + +P + S +TP P PS++AT
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP----- 591
Query: 1113 PESSVGAVSSLDRGCPDAP-APTSAPTSQQPEPVLGLGSVEQPHEVP-----SVLGTPLL 1166
P++ S +G P P +P + P Q P P L L ++ P P S L TP
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAP-PXLALPPLQAPPSPPASPPLSPLATPSP 650
Query: 1167 QPPENLA--------KGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDS 1218
Q P LA PS PV P P S P ++ +A PP + P Q
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQAPPSLAAPPLQVPP 708
Query: 1219 VEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDL 1278
PP S PP P AA PL P P SP +SP A+ +
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAA------PPLQVPPS---PPASPPMSPS-ATPPPRVP 758
Query: 1279 ALQILPPCQV---PPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGES 1335
L PP QV PP S P SP AP SP A GQ S
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS---P 815
Query: 1336 SAELDEQDILAPQTVQCPAQAP 1357
SA L + P P QAP
Sbjct: 816 SASLPMSPLATP-----PPQAP 832
Score = 91.3 bits (225), Expect = 7e-18
Identities = 199/776 (25%), Positives = 262/776 (33%), Gaps = 173/776 (22%)
Query: 483 VTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVT 542
+ P + P LQ + TP + + +T ++ PS + I I S+T
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP------PSLQTIPPIQVPHSLT 396
Query: 543 AEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAM 602
+ L P +L+ +L+ L P+ + + T+ PRQ + LT P A
Sbjct: 397 SPSLQAPPSPLALS-------SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449
Query: 603 TPP--LPLQ-----------DTDLSSAPKPVAAATIV------SQQAEEGLTLPQDSVMT 643
TPP PLQ T LS A P+++ + S A P S++
Sbjct: 450 TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIM 509
Query: 644 PPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 703
PPL +T+ S AP L P S TPPL + S AP P+
Sbjct: 510 PPL---ETQSSLAP--------------PSLQTPPASLTTPPL---ENLPSLAPPPL--- 546
Query: 704 TLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMT 763
Q A LT P TPP P AP P+ A P T
Sbjct: 547 ----QTASAPLTTPH--LETPPCP--------APCPLQA--------------PPSPLTT 578
Query: 764 PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM-TPP---------LPLQDTDL 813
PP +T S A P A ++ +GL P S + TPP PLQ
Sbjct: 579 PP---PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
Query: 814 SSAPKPVAAATIVSQQAEEGLT--LPQDSAMTPPLPLQDTDLS--SAPKPVAAATPVSQQ 869
A P++ S QA L L Q PP P S ++P +ATP SQ
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 695
Query: 870 ----AEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMA 925
A L +P + P+ T P P PLA A P + +P P AT
Sbjct: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-APPLQVPPSPPASPPMSPSATPP 754
Query: 926 QQEVG-EALGPRPAPEEKNAALP----TVPEPAALDQVQQDDPQ--PAAEAGTPWAAQED 978
+ A P P A+LP P P A + Q P+ A P A
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 979 ADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVEN 1038
++L M L+ P P + L+ P + P P TL+
Sbjct: 815 PSASLPMSPLATPPP------QAPPVLAAPLLQ------------VPPSPPASPTLQAPR 856
Query: 1039 QQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPT 1098
+ P GPR L A P PP+ P + L P S STPE
Sbjct: 857 RPPTP-GPDTSVSGPRLTLALA-PGPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEEL 911
Query: 1099 LPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPT--SQQPEPVLGLGSVEQPHE 1156
DS PE A PDA P S+ P P L
Sbjct: 912 --------RGYDSGPEGGAAASPP-----PDAELAACHPAAWSRGPAPPLAFRGAP---- 954
Query: 1157 VPSVLGTPLLQPP---ENLAKG----------QPSTPVDRPLGPDPSAPGTLAGAA 1199
G PL PP A G + +TP L P PS PGT G A
Sbjct: 955 -----GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS-PGTSGGKA 1004
Score = 89.0 bits (219), Expect = 3e-17
Identities = 243/992 (24%), Positives = 339/992 (34%), Gaps = 181/992 (18%)
Query: 498 VATRVTPQAGEEETDSTAGQESAAMAMP-QPSQEGISEILGQESVTAEKLPTPQEETSLT 556
+++ TP + + +A A A P QP +G+ +++ ++ P+++ +
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL------QALRPPQVTPPRKDAAPA 295
Query: 557 LCPDSPQNLKEEGGLDLPSGRK------PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQD 610
L P S L PSG K P AAT +P TLP + PLPL
Sbjct: 296 LGPLSSSPLATPS----PSGTKARPVPPPDNAATPLPA------TLPPSPPLATPLPLAP 345
Query: 611 TDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQA 670
S+ P + T+ S A P S+ TPP+ P + T+ Q
Sbjct: 346 PSPSAPP---SLQTLPSPPATPPSQAPP-SMTTPPMQA----------PPSLQTIPPIQV 391
Query: 671 EEGLTLPQDSAMTPPLPLQDTDL---SSAPKPVAAAT-----LVSQQAEEGLTLPQDSAM 722
LT P S PP PL + L +S P AT + +Q + LT P A
Sbjct: 392 PHSLTSP--SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449
Query: 723 TPP--LPLQ-----------DTDLSSAPKPVAAATLV------SQQAEEGLTLPQDSAMT 763
TPP PLQ T LS A P+++ + S A P S +
Sbjct: 450 TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIM 509
Query: 764 PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 823
PPL Q + L+ A++ + E +L T PL L + P P A
Sbjct: 510 PPLETQSS-LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP---A 565
Query: 824 TIVSQQAEEGLTLPQD---SAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDS 880
Q LT P S++ P P L+S P + P+S A P
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
Query: 881 AMTAPLPLQDTGPTSGP-EPLAVATPQTLQAEAGC---APGTEPVATMAQQEVGEALGPR 936
A+ PL + P S P PLA +PQ A A AP + P + Q P
Sbjct: 626 ALP-PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684
Query: 937 PAPEEKNAALPTVPEPA-ALDQVQQDDPQPAAEAGTPWAAQE-DADSTLGMEALSLPEPA 994
+P +A P+ P+ A +Q PA+ +P A A L L +P P+
Sbjct: 685 VSP---SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP-PS 740
Query: 995 SGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPR 1054
A ++ + + P R L A A P L+V L P
Sbjct: 741 PPASPPMSPSATPPPRVPPLLA-------APP-------LQVPPSPPASL--------PM 778
Query: 1055 SALGGAREVPDAPPAACPEVSQARLLSPAREERG-----------LSGKSTPEPTLPSAV 1103
S L A+ P APPA QA L SP G +S +TP P P +
Sbjct: 779 SPL--AKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
Query: 1104 ATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGT 1163
A A L P S +S P P PT P + P L L P PS +
Sbjct: 836 A--APLLQVPPSPP---ASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889
Query: 1164 PLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEE 1223
L P+ +T L S P A A+ PP A C
Sbjct: 890 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC-------------- 935
Query: 1224 PPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQIL 1283
PAA + G PL +P +PL P + D
Sbjct: 936 --------------HPAAWS-RGPAPPLA----FRGAPGAPLPWPPATGPGSAD------ 970
Query: 1284 PPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDE-- 1341
C + GP+S G P A G+G + S A L E
Sbjct: 971 GLCTIYETEGPESATPAPGALDPGPSPGTSG----GKAAAGAGAGASSRSPKQARLGELP 1026
Query: 1342 ---------QDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGV 1392
Q +L+ + A+ AGGS A+ AR A+S L + +
Sbjct: 1027 LGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAEL 1086
Query: 1393 TRITIQKSKNILFVIA-KPDVFKSPASDTYVV 1423
+ +I V + PD SP D VV
Sbjct: 1087 LSPLDESRASITSVTSFSPDDVASPQGDWTVV 1118
Score = 61.2 bits (147), Expect = 7e-09
Identities = 135/546 (24%), Positives = 178/546 (32%), Gaps = 55/546 (10%)
Query: 909 QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAE 968
+A+AG A T PRP P AAL + A+ + +
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 969 AGT-----PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDG 1023
T P A + T S P PASG GE A + RA
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRA--SGT 123
Query: 1024 AKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALG-GAREVPDAPPAACPEVSQARLLSP 1082
+P ++ L + + +E + A E RSAL GAR P P + AR
Sbjct: 124 TRPGPLGQKGLRI-SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 1083 AREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDA------PA---- 1132
A E GL + P S+ S E S S R P A PA
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 1133 -----PTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGP 1187
P S+P P G P G L+PP+ + + P PL
Sbjct: 243 SSSATPLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 1188 DPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAA-AAVSG 1246
P A + +G P+ PP P + PP L P P A P+A ++
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLP---ATLPPSPP--LATPLPLAPPSPSAPPSLQT 356
Query: 1247 TTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVP---PPSGPQSPAGPQGL 1303
P T P S +P S P A +LQ +PP QVP Q+P P L
Sbjct: 357 LPSPPATPP--SQAPPSMTTPPMQAPP-----SLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
Query: 1304 S---------APEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPA 1354
S +P Q L SPR + S S +S D + AP + PA
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTM-SPRQTQASLTSPSR-PASTPPDSPPLQAP--LSLPA 465
Query: 1355 QAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFK 1414
P S S +A+S L Q I +A P +
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525
Query: 1415 SPASDT 1420
PAS T
Sbjct: 526 PPASLT 531
Score = 37.4 bits (85), Expect = 0.11
Identities = 65/279 (23%), Positives = 87/279 (31%), Gaps = 45/279 (16%)
Query: 80 PSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTAL 139
PS P + +P+ P L + PL A P ET ++ +P
Sbjct: 539 PSLAPPPLQTASAPLTTPH-LETPPCPAPCPLQAPPSPLTTPPPETPSSIATP------- 590
Query: 140 RDQEGGHASPDPPPELCSQGDLSVPSPP------PDPDS--------FFTPPSTPTKTTY 185
P PP L S +PSPP P P + PPS P
Sbjct: 591 --------PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP-- 640
Query: 186 ALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGL 245
L P P A ++ A + SPP SP + S SPS + AP
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700
Query: 246 DFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPM 305
P SP S P PP + L S A+ PM
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP-------------ASPPM 747
Query: 306 IPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDP 344
P+A P + + ++V P P +A P P
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Score = 33.9 bits (76), Expect = 1.2
Identities = 76/309 (24%), Positives = 105/309 (33%), Gaps = 72/309 (23%)
Query: 13 PEADRPGPRTDLSCDAAAATT----------ILGGDRREPCA------LTP-------GP 49
P GPR +S + +TT GG + P + TP GP
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 50 SHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGP---SPMLLPEGLSSQAL- 105
S P+ P ++P+P+G P P GP SP+ P ++A
Sbjct: 258 SARGTPRAPAHP-SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 106 -----STEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGD 160
+ PLPATL P + T L P SP PP L Q
Sbjct: 317 VPPPDNAATPLPATLPPSPPLA--TPLPLAPP---------------SPSAPPSL--QTL 357
Query: 161 LSVPSPPPD--PDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSG 218
S P+ PP P S TPP + + P PH L L +PP+ +
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH--------SLTSPSLQAPPSPLAL 409
Query: 219 SYITADGDSWASSPSCSLSLLAPA-----EGLDFPSGWGLSPQGSMVDERELH-PAGTPE 272
S + A + + + S L + L PS P + D L P P
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS----RPASTPPDSPPLQAPLSLPA 465
Query: 273 PPSSESSLS 281
P ++SLS
Sbjct: 466 SPPLQTSLS 474
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 95.9 bits (237), Expect = 3e-19
Identities = 221/1073 (20%), Positives = 362/1073 (33%), Gaps = 158/1073 (14%)
Query: 468 VTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQP 527
V+ +A + ST + TP V+ + VT + +TA S ++ P
Sbjct: 2876 VSTTPVASSEASTLSTTP----------VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSE 2925
Query: 528 SQEGISEIL-------GQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSG---- 576
++ IL G E+ T P T +T ++ + G +P
Sbjct: 2926 VSTPLTSILVSTVPVAGSEASTLSTTPV-DTRTPVTTSAEASSSPTTAEGTSMPISTPGE 2984
Query: 577 -RKPVAAATI--VPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 633
R P+ + ++ +P + E TL + A T T+ SS+P I EG
Sbjct: 2985 RRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEG 3044
Query: 634 LT-LPQDSVMTPPLPLQDTE-LSSAP----KPVAAATLVSQQAE--EGLTLPQDSAMTPP 685
T L V T P+ + + LS+ P PV +T VS EG ++P +
Sbjct: 3045 STPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGS 3104
Query: 686 LPLQDTDLSSAP-----------KPVAAATLVSQQAE--------EGLTLPQDSAMTPPL 726
PL +S+ P PV +T V+ E EG ++P +
Sbjct: 3105 TPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGST 3164
Query: 727 PL-------------QDTDLSSAP----KPVAAAT-LVSQQAEEGLTLPQDSAMTPPLPL 768
PL +D+ LS+ P PV +T S EG ++P + PL
Sbjct: 3165 PLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPL 3224
Query: 769 QDTDLSSAPKPVAAATIVSQQAEEG---LTLPQDSAMTPP------LPLQDTDLSSAP-- 817
+S+ P + A+I+S + LT +++ +PP +P S P
Sbjct: 3225 TSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLT 3284
Query: 818 -KPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT--PVSQQAEEGL 874
PV+ T+ S + T P D++ P+ +S+ P+A T P S +E
Sbjct: 3285 SMPVSTTTVASSETSTLSTTPADTST----PVTTYSQASSSPPIADGTSMPTSTYSEGST 3340
Query: 875 TLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALG 934
L S T P+ + T P+ +TP T EA +P T ++ E
Sbjct: 3341 PLTNMSFSTTPV-VSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTT 3399
Query: 935 PRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPA 994
P A++P P +V P + E + S E SLP
Sbjct: 3400 PL-------ASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTST 3452
Query: 995 SGAG---------------EEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQ 1039
+ G A LS + + + P + + ++
Sbjct: 3453 TSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTA 3512
Query: 1040 QEGGL----KPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP 1095
EG P++ S P SQA SPA + STP
Sbjct: 3513 GEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQAS-SSPATLQVTTMRMSTP 3571
Query: 1096 EPTLPS--AVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQ 1153
S + ++ + E+S + S+DR P + S T PE +
Sbjct: 3572 SEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPE------VITL 3625
Query: 1154 PHEVPSVLGTPLLQPPENLAK------GQPST-PVDRPL-----GPDPSAPGTLAGAALP 1201
P PS + TPL P + G ST PVD S+P T G +P
Sbjct: 3626 PMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMP 3685
Query: 1202 ---PLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVS 1258
P E P V E GS P P V+ +T+ + + +
Sbjct: 3686 IWTPSEGSTPLTTMPVSTTRVTSSE--GSTLSTPSVVTSTP----VTTSTEAISSSATLD 3739
Query: 1259 LSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEED 1318
+ S + +++++ + + P + P S P P+ +S E
Sbjct: 3740 STTMSVSMPMEISTL-GTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEG-----SS 3793
Query: 1319 SPRAL-GSGQHSDSHGESSAELDEQDILAPQTVQCPAQA------PAGGSEETIAKAKQS 1371
SP L G+ S + L +++P +V P++A P S + K
Sbjct: 3794 SPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAG 3853
Query: 1372 RSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVF 1424
A ++ + + T+ S + + +P DT F
Sbjct: 3854 SFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTF 3906
Score = 93.6 bits (231), Expect = 1e-18
Identities = 214/972 (22%), Positives = 330/972 (33%), Gaps = 120/972 (12%)
Query: 384 TSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSW 443
TS S S + + S E +T+ DS S + A+D +++
Sbjct: 385 TSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIAT 444
Query: 444 AVEAAPQTSDRGAYLSQRQELISEVTEEGLA-LGQESTATVTPHTLQVAPGLQVEVATRV 502
+ + T +S SE + + ++ T + P +V
Sbjct: 445 STPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTS 504
Query: 503 TPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDS- 561
TP G ST + MP S E S + T+ + T E +S + P+
Sbjct: 505 TPSEG-----STPLTSMSVSTMPVASSEA-STLSTTPVDTSTPVTTSSEASSSSTTPEGT 558
Query: 562 --PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKP 619
P + EG L + PV+ +V +A T P DS + + S+ +
Sbjct: 559 SIPTSTPSEGSTPLTN--MPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEG 616
Query: 620 VAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE-LSSAPKPVAAATLVSQQAEEGLTLPQ 678
+ T S +E G T+ SV T + + LS+ P S +A T +
Sbjct: 617 TSMPT--STYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAE 674
Query: 679 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 738
++M P + PV + S +A T P D++ TP T+ SS+P
Sbjct: 675 GTSM-PTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTS-TPVTT--STEASSSPT 730
Query: 739 PVAAATLVSQQAEEGLTLPQDSAMTPPL--PLQDTDLSSAPKPVAAATIVSQQAEEGLTL 796
A++ + EG T ++ L + + LS+ P + S +A T
Sbjct: 731 TADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTT 790
Query: 797 PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 856
+ ++M P + + L ++ PV+ + S +A T P DS P+ T++SS+
Sbjct: 791 TEGTSMPISTPSEGSPLLTSI-PVSITPVTSPEASTLSTTPVDS--NSPVTTS-TEVSSS 846
Query: 857 PKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAP 916
P P + + EG T ++ L T P+ +TP T EA +P
Sbjct: 847 PTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSP 906
Query: 917 GTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQ 976
T +M P P E + L ++P+ P ++EA T A
Sbjct: 907 TTSEGTSM----------PTSTPGEGSTPLTSMPDSTT--------PVVSSEARTLSATP 948
Query: 977 EDADS--TLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETL 1034
D + T EA S P A G + S P G +P TL
Sbjct: 949 VDTSTPVTTSTEATSSPTTAEGT----SIPTSTPSE----------GTTPLTSTPVSHTL 994
Query: 1035 EVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKST 1094
V N + L + + L + E PP A G S
Sbjct: 995 -VANSEASTLSTTPVD--SNTPLTTSTEASSPPPTA-------------------EGTSM 1032
Query: 1095 PEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPT---SQQPEPVLGLGSV 1151
P T PS +T L P S+ SS PA TS P SQ
Sbjct: 1033 PTST-PSEGST--PLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGT 1089
Query: 1152 EQPHEVPSVLGTPLLQPP-------ENLAKGQPSTPVDRPL-----GPDPSAPGTLAGAA 1199
P S TPL P + A +TPVD + S+P T G +
Sbjct: 1090 SMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTS 1149
Query: 1200 L---PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSG--------TT 1248
+ PP E P L P ++ +L P + Q A + + T+
Sbjct: 1150 IPTSPPSEGTTP-LASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTS 1208
Query: 1249 QPLGT-GPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPP-----SGPQSPAGPQG 1302
P T G R + P+ VAS +A L+ P P SP +G
Sbjct: 1209 MPTSTPGERSTPLTSMPVRHTPVASSEASTLSTS---PVDTSTPVTTSAETSSSPTTAEG 1265
Query: 1303 LSAPEQQEDEDS 1314
S P E S
Sbjct: 1266 TSLPTSTTSEGS 1277
Score = 92.0 bits (227), Expect = 4e-18
Identities = 288/1427 (20%), Positives = 493/1427 (34%), Gaps = 186/1427 (13%)
Query: 12 LPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGAS 71
+P + RT L+ +TT++ + TP + +T + AR P +
Sbjct: 855 MPTSTYSEGRTPLT-SMPVSTTLVATSAISTLSTTPVDTSTPVT---NSTEARSSPTTSE 910
Query: 72 WDAGPGGAPSAWADPGEGGP---SPMLLPEG--LSSQALSTEAPLP----ATLEPRIVMG 122
+ P P + P P +P++ E LS+ + T P+ AT P G
Sbjct: 911 GTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEG 970
Query: 123 --------EETCQALLSPRAARTALRDQEGGHASPDPPPE---LCSQGDLSVPSPPPDPD 171
E L S + T + + E S P L + + S SPPP +
Sbjct: 971 TSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEAS--SPPPTAE 1028
Query: 172 SFFTPPSTPTK--TTYALLPACGPHGDARDSEAELRDELLDSPPASP----SGSYITADG 225
P STP++ T +P + ++ S P + S S TADG
Sbjct: 1029 GTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADG 1088
Query: 226 DSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSS 285
S +S S P + + +S + S + P T P ++ + S+ +
Sbjct: 1089 TSMPTSTYSEGS--TPLTSVPVSTRLVVSSEASTLSTT---PVDTSIPVTTSTEASSSPT 1143
Query: 286 SSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEA--VEVTPLSPEEEEEEAVADPD 343
++ G ++ P A +P +L+ EA + TP+ + + +
Sbjct: 1144 TAEGTSIPTSP----PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASS 1199
Query: 344 PGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDER 403
P ST L+ + + T ASS++ + S + D
Sbjct: 1200 PPPTAEVTSMPTSTPGERSTPLTSMPVRH-----------TPVASSEASTLSTSPVDTST 1248
Query: 404 --LYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSD-------- 453
S E + T + + T S G VS + +P+ S
Sbjct: 1249 PVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP---VSTTLVTSPEASTLLTTPVDT 1305
Query: 454 RGAYLSQRQELISEVTEEGLALGQES--------------TATVTPHTLQVAPGLQVEVA 499
+G ++ + S EG ++ + T V + + V+ +
Sbjct: 1306 KGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNS 1365
Query: 500 TRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCP 559
T VT E S E +M PS EG + + T + + S T
Sbjct: 1366 TPVTTST--EACSSPTTSEGTSMPNSNPS-EGTTPLTSIPVSTTPVVSSEASTLSATPVD 1422
Query: 560 DSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDL-TLPQDSAMTPPLPLQDTDLSSAP- 617
S P+ + ++ T P + K L ++P + TP + + LS+ P
Sbjct: 1423 TSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN--TPVANSEASTLSTTPV 1480
Query: 618 ---KPVAAATIVSQQAE--EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEE 672
PV +T VS EG ++ ++ TP T L+S P V+ T+ S +
Sbjct: 1481 DSNSPVVTSTAVSSSPTPAEGTSI---AISTPSEG--STALTSIP--VSTTTVASSEINS 1533
Query: 673 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTD 732
T P A+T + SS+P ++ + EG T ++ L +
Sbjct: 1534 LSTTP---AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEA 1590
Query: 733 LSSAPKPVAAATLVSQQAE-EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 791
+ + P+ + T V+ E T + S+MT P + + L ++ PV+ + S +A
Sbjct: 1591 NTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSI-PVSTTPVASPEAS 1649
Query: 792 EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDT 851
T P DS P+ + T++SS+P P ++ + EG T P S P+ +
Sbjct: 1650 TLSTTPVDS--NSPV-ITSTEVSSSPTPAEGTSMPTSTYTEGRT-PLTSITVRTTPVASS 1705
Query: 852 DLSS-APKPVAAATPVSQQAE--------EGLTLPQDSAMTAPLPLQDTGPTSGP----- 897
+S+ + PV +TPV+ E EG ++P + PL ++ P
Sbjct: 1706 AISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSE 1765
Query: 898 ------EPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPA--------PEEKN 943
P+ +TP T EA +P T ++ + E + P + +
Sbjct: 1766 ASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEA 1825
Query: 944 AALPTVP----EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGE 999
+ L T P P P PA GT A ++ + + S+P +
Sbjct: 1826 STLSTTPVDSNSPVVTSTAVSSSPTPA--EGTSIATSTPSEGSTAL--TSIPVSTTTVAS 1881
Query: 1000 EIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGG 1059
LS + + P + ++ +EG +P +
Sbjct: 1882 SETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREG--RPPLTSIPVSTTTVA 1939
Query: 1060 AREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPT-LPSAVATEAS--LDSCPESS 1116
+ E+ + S A S +T + T +P+ +E S L S P S+
Sbjct: 1940 SSEINTLSTTLADTRTPVTTYSQAS-----SSPTTADGTSMPTPAYSEGSTPLTSMPLST 1994
Query: 1117 VGAVSSLDRGCPDAPAPTSAPTSQQPE----PVLGLGSVEQPHEVPSVLGTPLLQPPENL 1172
VSS P TS P + E P G+ Q PS TPL P +
Sbjct: 1995 TLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQT-STPSERTTPLAGMPVST 2053
Query: 1173 -----AKGQ--PSTPVDRPL----GPDPSAPGTLAGAALPPLEPP--APCLCQDPQEDSV 1219
++G +TPVD + S+ T G+++ P +P L P +
Sbjct: 2054 TLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTP 2113
Query: 1220 EDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGT-GPRVSLSPHS----PLLSPKVASMD 1274
+L P + P + ++ P+ T G + S +S PL S V++
Sbjct: 2114 VASPEASTLSTTPVDSN-SPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTV 2172
Query: 1275 AKDLALQIL--PPCQVPPP-----SGPQSPAGPQGLSAPEQQEDEDS 1314
A+ L P P SP +G S P E S
Sbjct: 2173 VASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGS 2219
Score = 90.5 bits (223), Expect = 1e-17
Identities = 212/1036 (20%), Positives = 357/1036 (34%), Gaps = 173/1036 (16%)
Query: 384 TSAASSDSDSASYAEADDERLY-SGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVS 442
T +A++ + + + R+Y S + + T ++ SV G+ + T +
Sbjct: 61 TGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSD-------TPGVSSTRMTPT 113
Query: 443 WAVEAAPQTSDRGA-YLSQRQELISEVTEEG----LALGQESTATVTPHTLQVAPGLQVE 497
+ + TSD + S ++ S T EG ++ E + + T + AP E
Sbjct: 114 ESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFE 173
Query: 498 VATRVTPQAGEEETDSTAGQESAAMAMPQPS-------QEGISEILGQESVTAEK----- 545
T +T + +T+ Q S++ P+ + EG + + + T +
Sbjct: 174 AYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEA 233
Query: 546 ---LPTPQE-ETSLTLCPDSPQNLKEEGGLDL----PSG------RKPVAAATIVPRQAK 591
L TP E T +T+ + + G L PSG R P++ +V +A
Sbjct: 234 ITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEAS 293
Query: 592 EDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLT---------------- 635
TL A T + T+ SS+P +I + EG T
Sbjct: 294 ---TLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSE 350
Query: 636 ---LPQDSVMTPPLPLQDTELSSAP----------------------KPVAAATLVSQQA 670
L V T L TE SS P PV+ + S +A
Sbjct: 351 MSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEA 410
Query: 671 EEGLTLPQDS---------AMTPPLPLQDTDLSSA----------PKPVAAATLVSQQAE 711
T+P DS A + P +DT ++++ PV+ + S +A
Sbjct: 411 STTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEAS 470
Query: 712 EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 771
T P DS T+ SS+P ++ + EG T P S +P+ +
Sbjct: 471 NLSTTPVDSKTQ---VTTSTEASSSPPTAEVNSMPTSTPSEGST-PLTSMSVSTMPVASS 526
Query: 772 D---LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQ-DTDLSSAPKPVAAATIVS 827
+ LS+ P + S +A T P+ +++ P + T L++ PV+ +VS
Sbjct: 527 EASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTN--MPVSTRLVVS 584
Query: 828 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLP 887
+A T P DS + SS+ + P S +E G T+ S T L
Sbjct: 585 SEASTTSTTPADS--NTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTT-LV 641
Query: 888 LQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPA--------P 939
T P+ TP T EA + T +M E P +
Sbjct: 642 ASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVA 701
Query: 940 EEKNAALPTVP----EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPAS 995
+ + L T P P P A A P + + + L S+P +
Sbjct: 702 SSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPL----TSMPVSKT 757
Query: 996 GAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRS 1055
A LS + T P + + ++ + EG PL +
Sbjct: 758 LLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEG--SPLL------T 809
Query: 1056 ALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPE--PTLPSAVATE--ASLDS 1111
++ + +P A+ + SP +S TP ++P++ +E L S
Sbjct: 810 SIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTS 869
Query: 1112 CPES----SVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQ 1167
P S + A+S+L D P + T + P G+ P P TPL
Sbjct: 870 MPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGT-SMPTSTPGEGSTPLTS 928
Query: 1168 PPENL-------AKGQPSTPVD--RPLGPD---PSAPGTLAGAALP---PLEPPAPCLCQ 1212
P++ A+ +TPVD P+ S+P T G ++P P E P L
Sbjct: 929 MPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTP-LTS 987
Query: 1213 DPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHS--------- 1263
P ++ +L P + + + + P G + S S
Sbjct: 988 TPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRM 1047
Query: 1264 PLLSPKVASMDAKDLA 1279
P+ + VAS + L+
Sbjct: 1048 PVSTTMVASSETSTLS 1063
Score = 81.6 bits (200), Expect = 5e-15
Identities = 248/1216 (20%), Positives = 409/1216 (33%), Gaps = 147/1216 (12%)
Query: 88 EGGPSPMLLPEGLS---SQALSTEAPLPATLEPRI-VMGEETCQALLSPRAARTALRDQE 143
EG SP EG S S PL + L + V G E +P RT +
Sbjct: 2905 EGSSSPTTA-EGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTS- 2962
Query: 144 GGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAE 203
AS P + +S P P + + + P ++ A + P A S
Sbjct: 2963 -AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTP---ADTSTPV 3018
Query: 204 LRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGS---MV 260
S P + G+ I S S+P S+ + + S +P S +V
Sbjct: 3019 TTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVV 3078
Query: 261 DERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQ 320
E+ + TP +S +S S S G +P + P S I
Sbjct: 3079 TSTEVSSSPTPAEGTS-MPISTYSEGSTPLTG-------------VPVSTTPVTSSAIST 3124
Query: 321 VEAVEVTPLSPEEEEEEAVADPDPGGDLA---GEGEEDSTSASFLQSLSDLSITEGMDEA 377
+ V +P EA + P + E ST +++ + L ++
Sbjct: 3125 LSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTL 3184
Query: 378 FAFRDDTSA-ASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQA 436
A DTS ++ +++ S A+ + + P T L + A L
Sbjct: 3185 SATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILST 3244
Query: 437 QDG------TVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQV 490
T S ++P T++ G + + + + A+ TL
Sbjct: 3245 TPVDSNTPLTTSTEASSSPPTAE-GTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLST 3303
Query: 491 APGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQ 550
P + +T VT + + A S MP + S L S + + + +
Sbjct: 3304 TPA---DTSTPVTTYSQASSSPPIADGTS----MPTSTYSEGSTPLTNMSFSTTPVVSSE 3356
Query: 551 EETSLTLCPDS--PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPL 608
T T D+ P E L A T +P + + T P S P+
Sbjct: 3357 ASTLSTTPVDTSTPVTTSTEASLS-----PTTAEGTSIPTSSPSEGTTPLASMPVSTTPV 3411
Query: 609 QDTDLSS-APKPVAAATIVSQQAE--------EGLTLPQDSVMTPPLPLQDTELSSAPKP 659
+++++ + PV + T+V+ E EG +LP + PL LS+ P
Sbjct: 3412 VSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVA 3471
Query: 660 VAAATLVSQQAEEGLT-----LPQDSAMTPP----LPLQDTDLSSAP---KPVAAATLVS 707
+ A+ +S + T P +S+ T +P S P PV+ + S
Sbjct: 3472 SSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVAS 3531
Query: 708 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 767
+A T P DS + SS+P + T+ EG S++T L
Sbjct: 3532 SEASTLSTTPVDSNT---FVTSSSQASSSPATLQVTTMRMSTPSEG-----SSSLTTML- 3582
Query: 768 LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPP----LPLQDTDLSSAP---KPV 820
L T ++S+ + V + + +S TPP LP+ S P PV
Sbjct: 3583 LSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPV 3642
Query: 821 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDS 880
+ ++ +A TLP D++ TP + T +SS+P T EG T
Sbjct: 3643 STTSVTISEAGTASTLPVDTS-TPVIT--STQVSSSPVTPEGTTMPIWTPSEGSTPLTTM 3699
Query: 881 AMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGE--------A 932
++ G T + +TP T EA + T TM+ E
Sbjct: 3700 PVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTIL 3759
Query: 933 LGPRPA---PEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALS 989
+ P PE ++P+V ++ + P GT +
Sbjct: 3760 VSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTV 3819
Query: 990 LPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVE--NQQEGGLKPL 1047
L P S A LS P + T G+ + T+ + +++ L L
Sbjct: 3820 LISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTL 3879
Query: 1048 AQEHGPRSALGGAREVPDAPP-------------AACPEVSQARLLSPAREERGLSGKST 1094
++ GA + PP A+ P + A +S + G ST
Sbjct: 3880 LVSTTLPTSFPGA-SIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEG----ST 3934
Query: 1095 PEPT--LPSAVATEASLDSCPESSVGAVSS--LDRGCPDAPAPTSAPTSQQPEPVLGLGS 1150
P T +PS T ++ D P ++ GAVS+ + + P+ +S+ T+ +
Sbjct: 3935 PGTTIFIPSTPVTSSTADVFP-ATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTT 3993
Query: 1151 VEQPHEVPSVLGTPLLQP--PENLAKG---------QPSTP------VDRPLGP--DPSA 1191
P T P P ++G STP RP+ P + S
Sbjct: 3994 PAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSR 4053
Query: 1192 PGTLAGAALPPLEPPA 1207
P T+ +PP PPA
Sbjct: 4054 PSTITSHTIPPTFPPA 4069
Score = 77.8 bits (190), Expect = 7e-14
Identities = 257/1186 (21%), Positives = 400/1186 (33%), Gaps = 133/1186 (11%)
Query: 217 SGSYITADGDS-WASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPS 275
S S TA G S S+PS P G+ + +S +G+ + TP
Sbjct: 2023 SSSPTTAGGTSIQTSTPS---ERTTPLAGMPVSTTLVVSSEGNTLST-------TPVDSK 2072
Query: 276 SESSLSADSSSSWGQEGHFFDLDFLAN-DPM---IPAALLPFQGSLIFQVEAVEVTPLSP 331
++ + S ++SSS EG + + P+ IP + P + V SP
Sbjct: 2073 TQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSP 2132
Query: 332 EEEEEEAVADPDP--GGDLAGEGEED----------STSASFLQSLSDLSITEGMDEAFA 379
E + P P G + D ST+ ++S LS T +D +
Sbjct: 2133 VITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTP-VDTSTP 2191
Query: 380 FRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDG 439
+ T A SS + S + P + V +E + +
Sbjct: 2192 VTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPV 2251
Query: 440 TVSWAVEAAPQTSDRGAY----LSQRQELISE--VTEEGLALGQESTATVTPHTLQVAPG 493
T S ++P T++ + LS+ ++ V+ +A + ST + TP
Sbjct: 2252 TTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFT 2311
Query: 494 LQVEVATRVTPQAGEEETDSTAGQESAAMA-MPQPSQEGISEILGQESVTAEKLPTP--- 549
E ++ G ST+ + + + MP + S S T TP
Sbjct: 2312 TSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTT 2371
Query: 550 --QEETSLTLCPDS--PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPP 605
Q +S T D+ P + EG L S PV+ +V +A T P D++ TP
Sbjct: 2372 YSQAGSSPTTADDTSMPTSTYSEGSTPLTS--VPVSTMPVVSSEASTHSTTPVDTS-TPV 2428
Query: 606 LPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE---LSSAPKPVAA 662
T+ SS+P +I + EG T P S+ P+ +E LS+ P +
Sbjct: 2429 TT--STEASSSPTTAEGTSIPTSPPSEGTT-PLASMPVSTTPVVSSEAGTLSTTPVDTST 2485
Query: 663 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAM 722
S +A T +D + + + L ++ PV+ + S +A T P DS
Sbjct: 2486 PMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSI-PVSTTPVASPEASTLSTTPVDS-- 2542
Query: 723 TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTD---LSSAPKP 779
P+ + T++SS+ ++ + EG T P S PL ++ LS+ P
Sbjct: 2543 NSPV-VTSTEISSSATSAEGTSMPTSTYSEGST-PLRSMPVSTKPLASSEASTLSTTPVD 2600
Query: 780 VAAATIVSQQAEEGLTLPQDSAMTPPLPLQ-DTDLSSAPKPVAAATIVSQQAEEGLTLPQ 838
+ S + T +D++M P + T L+S V+ + S +A T P
Sbjct: 2601 TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSIL--VSTMPVASSEASTLSTTPV 2658
Query: 839 DSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPE 898
D T L T SS+P ++ + E T + ++ L T
Sbjct: 2659 D---TRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTT 2715
Query: 899 PLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQV 958
P+ +TP T AEA +P T +M + G P + LP A+
Sbjct: 2716 PVDTSTPVTTSAEASSSPTTAEGTSMRISTPSD--GSTPLTSILVSTLPVASSEASTVST 2773
Query: 959 QQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARA 1018
D T E + S E S+ P S E S P + A
Sbjct: 2774 TAVDTSIPVTTST-----EASSSPTTAEVTSM--PTSTPSETSTPLTSMPVNHTPV---A 2823
Query: 1019 HTGDGAKPDSPQKETLEVENQQEGGLKPLAQEH---GPRSALGGAREVPDAPPAACPEV- 1074
+ G +P + V + P E +A G+ + P + P
Sbjct: 2824 SSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVAS 2883
Query: 1075 SQARLLSP---------AREERGLSGKSTPEPT-LPSAVATEAS--LDSCPESSVGAVSS 1122
S+A LS G S +T E T +P + +E S L S S+V S
Sbjct: 2884 SEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGS 2943
Query: 1123 LDRGCPDAPAPTSAPTSQQPE-------------PVLGLGSVEQPHEVPSVLGTPLLQPP 1169
P T P + E P+ G P SV P+
Sbjct: 2944 EASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSE 3003
Query: 1170 ENLAKGQP---STPVDRPLGPDPSAPGTLAGAALP---PLEPPAPCLCQDP--------Q 1215
+ P STPV S+P T G +P P E P L P
Sbjct: 3004 ASTLSRTPADTSTPVTTSTEAS-SSPTTAEGTGIPISTPSEGSTP-LTSIPVSTTPVAIP 3061
Query: 1216 EDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDA 1275
E S P S V + GT+ P+ T S +PL V++
Sbjct: 3062 EASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGS----TPLTGVPVSTTPV 3117
Query: 1276 KDLALQIL--PPCQVPPP-----SGPQSPAGPQGLSAPEQQEDEDS 1314
A+ L P P SP +G S P E S
Sbjct: 3118 TSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGS 3163
Score = 46.6 bits (109), Expect = 2e-04
Identities = 88/411 (21%), Positives = 134/411 (32%), Gaps = 75/411 (18%)
Query: 479 STATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEG------- 531
ST VT P + + A E + T + + M M S+
Sbjct: 3761 STTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVL 3820
Query: 532 ISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAK 591
IS I A L TP +TS L + + G +P+ + + R
Sbjct: 3821 ISPISVMSPSEASTLSTPPGDTSTPLLTST-----KAGSFSIPAEVTTIRISITSERSTP 3875
Query: 592 -----EDLTLPQDS-----AMTPPLPLQ-----DTDLSSAPKPVAAATIVSQQAEEGLTL 636
TLP A TPPL TD +S P A TI EG T
Sbjct: 3876 LTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGST- 3934
Query: 637 PQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 696
P ++ P P+ + P A + TP + T+L++
Sbjct: 3935 PGTTIFIPSTPVTSSTADVFPATTGAVS------------------TPVIT--STELNT- 3973
Query: 697 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP---KPVAAATLVSQQAEEG 753
P +++T S + T P AMT PL +S+AP + + S
Sbjct: 3974 PSTSSSSTTTSFSTTKEFTTP---AMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSA 4030
Query: 754 LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL------- 806
+ P S P+ + SS P + + TI T P + TPP
Sbjct: 4031 TSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPP-------TFPPAHSSTPPTTSASSTT 4083
Query: 807 --PLQDTDLSSAPKP----VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDT 851
P T +++ KP + T+ + T+ + TP +P T
Sbjct: 4084 VNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTT 4134
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 90.9 bits (224), Expect = 9e-18
Identities = 198/908 (21%), Positives = 310/908 (34%), Gaps = 130/908 (14%)
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPD 560
+ P +G +T + + S P+++ +++ E +T E + +E+S +
Sbjct: 77 KAPPPSGASQTIKSTTKRSPK----PPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 132
Query: 561 SPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPV 620
S +++TI R+ K + + L ++D + K
Sbjct: 133 S-------------------SSSTI--RKIKSSKNSAANRELQKKLKVKDNKKNRTKKKP 171
Query: 621 AAATIVSQQAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATLVSQQA--------- 670
V +A GL V TP Q ++S++PK A + + +
Sbjct: 172 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 231
Query: 671 EEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 729
E LT+ +++ + T + S+ K + +Q E+ T +D A T + +
Sbjct: 232 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK--TSAKDLAPTSKVLAK 289
Query: 730 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK------PVAAA 783
T + A T + T P++ A T P T + SAP P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTP---TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 346
Query: 784 TIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT 843
+ + E T ++ A T P T + P P + + E T P+ A T
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 844 PPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVA 903
P T P P P E T P++ A TAP + PT+ EP A
Sbjct: 406 TPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KKPAPTTPKEP-APT 460
Query: 904 TPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALD----QVQ 959
TP+ EP T +E PAP +A T EPA
Sbjct: 461 TPK------------EPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 507
Query: 960 QDDPQP-AAEAGTPWAAQEDADSTLGMEALSLP-EPASGAGEEIAEALS-RPGREACLEA 1016
+P P + P +E A +T A + P EPA +E A + +P E
Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567
Query: 1017 RAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQ 1076
T P +P+K T P + A P+ P PE
Sbjct: 568 APTTPKETAPTTPKKLT-------------------PTTPEKLAPTTPEKPAPTTPE--- 605
Query: 1077 ARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSA 1136
L EE + P PT P A A + P + + P PAPT+
Sbjct: 606 -ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT----TPKEPAPTT- 659
Query: 1137 PTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLA----KGQPSTPVDRPLGPDPSAP 1192
P P G P+ TP P+ LA K ST D+P AP
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCDKP------AP 710
Query: 1193 GTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLG 1252
T G A + PAP ++P + + P +L P P +PA ++ TT
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT-TLKEPAPTTPKKPAPKELAPTTT--- 766
Query: 1253 TGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDE 1312
GP + S +PK + P + P P+ P++P + E
Sbjct: 767 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKE 824
Query: 1313 DSLEEDSPRALGSGQHSDSHGESSAELDEQDI-LAPQTVQCP-AQAPAGGSEETIAKAKQ 1370
+ SP +S E SAE + + +P+ P + PA E AK
Sbjct: 825 PTTIHKSP--------DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKD 876
Query: 1371 SRSEKKAR 1378
+E+ R
Sbjct: 877 KTTERDLR 884
Score = 63.2 bits (152), Expect = 2e-09
Identities = 109/516 (21%), Positives = 161/516 (31%), Gaps = 59/516 (11%)
Query: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505
E AP T A + ++ + E +E T T P T+ P
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491
Query: 506 AGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNL 565
+E +T P P+ T E PT +E + T
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPT------------TTKEPAPTTPKEPAPTTPKKPAPTT 539
Query: 566 KEEGGLDLPSGRKPVAAATIVPRQAKEDL-TLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 624
+E P P P KE T P+++A T P L T
Sbjct: 540 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599
Query: 625 IVSQQAEEGLTLPQDSV-MTPPLPLQDTELSSAPKPVA--AATLVSQQA-----EEGLTL 676
+ E T P++ TP P T ++AP A T + A E T
Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659
Query: 677 PQDSAMTPPL---------PLQDTDLSSAPKPVAAATLVSQQA----EEGLTLPQDSAMT 723
P+++A T P P T APK +A T + + T P+ +A T
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 719
Query: 724 PPL---------PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 774
P P T +AP + + + L + P D
Sbjct: 720 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779
Query: 775 SAPKPVAAATIVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 833
+ PK A T E T P+ A TP P T S P T + + +E
Sbjct: 780 TTPKETAPTT----PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE- 834
Query: 834 LTLPQDSAMTPPLPLQD---------TDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 884
+ P+ SA P L++ T +A KP T + E L ++ A
Sbjct: 835 -STPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 893
Query: 885 PLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
P ++T T+ + T T Q + T P
Sbjct: 894 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 929
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 90.9 bits (224), Expect = 9e-18
Identities = 198/908 (21%), Positives = 310/908 (34%), Gaps = 130/908 (14%)
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPD 560
+ P +G +T + + S P+++ +++ E +T E + +E+S +
Sbjct: 118 KAPPPSGASQTIKSTTKRSPK----PPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 173
Query: 561 SPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPV 620
S +++TI R+ K + + L ++D + K
Sbjct: 174 S-------------------SSSTI--RKIKSSKNSAANRELQKKLKVKDNKKNRTKKKP 212
Query: 621 AAATIVSQQAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATLVSQQA--------- 670
V +A GL V TP Q ++S++PK A + + +
Sbjct: 213 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 272
Query: 671 EEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 729
E LT+ +++ + T + S+ K + +Q E+ T +D A T + +
Sbjct: 273 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK--TSAKDLAPTSKVLAK 330
Query: 730 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK------PVAAA 783
T + A T + T P++ A T P T + SAP P
Sbjct: 331 PTPKAETTTKGPALTTPKEPTP---TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 387
Query: 784 TIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT 843
+ + E T ++ A T P T + P P + + E T P+ A T
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 844 PPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVA 903
P T P P P E T P++ A TAP + PT+ EP A
Sbjct: 447 TPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KKPAPTTPKEP-APT 501
Query: 904 TPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALD----QVQ 959
TP+ EP T +E PAP +A T EPA
Sbjct: 502 TPK------------EPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 548
Query: 960 QDDPQP-AAEAGTPWAAQEDADSTLGMEALSLP-EPASGAGEEIAEALS-RPGREACLEA 1016
+P P + P +E A +T A + P EPA +E A + +P E
Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608
Query: 1017 RAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQ 1076
T P +P+K T P + A P+ P PE
Sbjct: 609 APTTPKETAPTTPKKLT-------------------PTTPEKLAPTTPEKPAPTTPE--- 646
Query: 1077 ARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSA 1136
L EE + P PT P A A + P + + P PAPT+
Sbjct: 647 -ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT----TPKEPAPTT- 700
Query: 1137 PTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLA----KGQPSTPVDRPLGPDPSAP 1192
P P G P+ TP P+ LA K ST D+P AP
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCDKP------AP 751
Query: 1193 GTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLG 1252
T G A + PAP ++P + + P +L P P +PA ++ TT
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT-TLKEPAPTTPKKPAPKELAPTTT--- 807
Query: 1253 TGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDE 1312
GP + S +PK + P + P P+ P++P + E
Sbjct: 808 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKE 865
Query: 1313 DSLEEDSPRALGSGQHSDSHGESSAELDEQDI-LAPQTVQCP-AQAPAGGSEETIAKAKQ 1370
+ SP +S E SAE + + +P+ P + PA E AK
Sbjct: 866 PTTIHKSP--------DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKD 917
Query: 1371 SRSEKKAR 1378
+E+ R
Sbjct: 918 KTTERDLR 925
Score = 63.2 bits (152), Expect = 2e-09
Identities = 109/516 (21%), Positives = 161/516 (31%), Gaps = 59/516 (11%)
Query: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505
E AP T A + ++ + E +E T T P T+ P
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532
Query: 506 AGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNL 565
+E +T P P+ T E PT +E + T
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPT------------TTKEPAPTTPKEPAPTTPKKPAPTT 580
Query: 566 KEEGGLDLPSGRKPVAAATIVPRQAKEDL-TLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 624
+E P P P KE T P+++A T P L T
Sbjct: 581 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640
Query: 625 IVSQQAEEGLTLPQDSV-MTPPLPLQDTELSSAPKPVA--AATLVSQQA-----EEGLTL 676
+ E T P++ TP P T ++AP A T + A E T
Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700
Query: 677 PQDSAMTPPL---------PLQDTDLSSAPKPVAAATLVSQQA----EEGLTLPQDSAMT 723
P+++A T P P T APK +A T + + T P+ +A T
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 760
Query: 724 PPL---------PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 774
P P T +AP + + + L + P D
Sbjct: 761 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820
Query: 775 SAPKPVAAATIVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 833
+ PK A T E T P+ A TP P T S P T + + +E
Sbjct: 821 TTPKETAPTT----PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE- 875
Query: 834 LTLPQDSAMTPPLPLQD---------TDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 884
+ P+ SA P L++ T +A KP T + E L ++ A
Sbjct: 876 -STPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 934
Query: 885 PLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
P ++T T+ + T T Q + T P
Sbjct: 935 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 970
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 89.0 bits (219), Expect = 3e-17
Identities = 216/901 (23%), Positives = 316/901 (35%), Gaps = 180/901 (19%)
Query: 507 GEEETDSTAGQESAAMAMPQPSQEGISEIL---GQESVTAEKL---------PTPQEETS 554
G + T + A A+ P+P Q + ++ GQ + ++ PTP
Sbjct: 1213 GNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPV 1272
Query: 555 LTLCPDSPQNLKEEGGLDLPSGRKPV--------AAATIVPRQAKEDLTLPQDSAMTPPL 606
L +P GL LP V IV RQA D +TP
Sbjct: 1273 SVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRD-------GLTPVP 1325
Query: 607 PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP---PLPLQDTELSSAPKPVAAA 663
PL + AP+P ++ L +TP P P T + P P
Sbjct: 1326 PL-----APAPRPPSSGLPA--------VLNPRPTLTPGRLPTPTLGTARAPMPTPTLVR 1372
Query: 664 TLV----SQQAEEGLTLPQDSAMTPPLPLQDTDL----SSAPKPVAAATLVSQQAEEGLT 715
L+ S E + P + +T PL +S+P P+ ++ ++ ++
Sbjct: 1373 PLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVS 1432
Query: 716 LPQDSAMTPPLPLQDTDLSSAPK--PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDL 773
+P S++ +P +SAP P++A VS LT ++TPPL +
Sbjct: 1433 VPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLT-----SVTPPLA---PVV 1484
Query: 774 SSAPKPVAAATIVSQQAEEGLTL------PQDSAMTP--PLPLQDTD-----LSSAPKPV 820
+AP P + A + + LTL S+ TP PL L T L+S P
Sbjct: 1485 PAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPA 1544
Query: 821 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA-ATPVSQQA--EEGLTLP 877
+ +V A L P SA P P Q + L+ A A ATP++ A + + P
Sbjct: 1545 CSPVLVPASA---LASPFPSAPNPA-PAQASLLAPASSASQALATPLAPMAAPQTAILAP 1600
Query: 878 QDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRP 937
+ APLP+ P + P + TP + A P + P ++A A P
Sbjct: 1601 SPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMA-----PSSTPGTSLASASPVPAPTPVL 1655
Query: 938 APEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGA 997
AP LP P P+ L A A P TL + +
Sbjct: 1656 APSSTQTMLPA-PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGT------GNPQ 1708
Query: 998 GEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSAL 1057
G + LS + + A T A P P T Q L P A P S +
Sbjct: 1709 GPFPTQTLSLTPASSLVPTPAQTLSLA-PGPPLGPT------QTLSLAP-APPLAPASPV 1760
Query: 1058 GGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSV 1117
G A P P S A LL+PA + L+ P PTL A A +L
Sbjct: 1761 GPA---PAHTLTLAPASSSASLLAPASVQT-LTLSPAPVPTLGPAAAQTLAL-------- 1808
Query: 1118 GAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQP 1177
APA T +P SQ V+ S P V V P+ +K +P
Sbjct: 1809 ------------APASTQSPASQASSLVVS-ASGAAPLPVTMVSRLPV-------SKDEP 1848
Query: 1178 STPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQE----DSVEDE----------- 1222
T R P P + T G P +PP P P+ DS+E++
Sbjct: 1849 DTLTLRSGPPSPPSTATSFGGPRPRRQPPPP-----PRSPFYLDSLEEKRKRQRSERLER 1903
Query: 1223 -----EPPGSLG------------LPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPL 1265
E G+L LP P A P G + P T + + H +
Sbjct: 1904 IFQLSEAHGALAPVYGTEVLDFCTLPQPVAS--PIGPRSPGPSHP--TFWTYTEAAHRAV 1959
Query: 1266 LSPKVASMDAKDLA---LQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDS-PR 1321
L P+ ++ + ++PP + PPPS P AP Q ++ L + PR
Sbjct: 1960 LFPQQRLDQLSEIIERFIFVMPPVEAPPPS--LHACHPPPWLAPRQAAFQEQLASELWPR 2017
Query: 1322 A 1322
A
Sbjct: 2018 A 2018
Score = 86.3 bits (212), Expect = 2e-16
Identities = 225/932 (24%), Positives = 327/932 (35%), Gaps = 168/932 (18%)
Query: 526 QPSQEGISEIL----GQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVA 581
QP+ + ++L G S T+ PTP +L+L P P ++ L P +
Sbjct: 1076 QPNSGSLPQVLPSPLGVLSGTSRP-PTP----TLSLKPTPPAPVR------LSPAPPPGS 1124
Query: 582 AATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSV 641
++ + P T P +A T ++ P P A + + LP V
Sbjct: 1125 SSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEV 1184
Query: 642 MTPPLPLQDTELSS-APKPVAAA----TLVSQQAEEGLTLP----QDSAMTPPLPLQDTD 692
++ +L+S A +PVA A L Q LTL + A+ P PLQ +
Sbjct: 1185 VSIG------QLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQ-RN 1237
Query: 693 LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP-PLPLQDTDLSSAPKPVAAATLVSQQAE 751
+ L+SQ A + L Q A TP P P+ SS P A T
Sbjct: 1238 VVHLVSAGGQHHLISQPAH--VALIQAVAPTPGPTPVSVLP-SSTPSTTPAPT------- 1287
Query: 752 EGLTLPQDSAMTPPLPLQDTDL-----SSAPK----PVAAATIVSQQAEEGL--TLPQDS 800
GL+LP + PP + +T + AP+ PV + GL L
Sbjct: 1288 -GLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRP 1346
Query: 801 AMTP---PLPLQDTDLSSAPKPVAAATIV----SQQAEEGLTLPQDSAMTPPLPLQDTDL 853
+TP P P T + P P ++ S E + P + +T PL
Sbjct: 1347 TLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSS 1406
Query: 854 ----SSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQ 909
+S+P P+ ++P++ +++P S++ +P P S P + ++ P T+
Sbjct: 1407 LPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVS 1466
Query: 910 AE---------------AGCAPGTEPVATMAQQEVGEA--LGPRPAPEEKNAALPTVP-- 950
A APG +A A LG AP ++ P P
Sbjct: 1467 ASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLL 1526
Query: 951 -------------------EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLP 991
P + P P+A P A A ++ +AL+ P
Sbjct: 1527 LAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATP 1586
Query: 992 EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEH 1051
A + A S A L A GA P +T + +A
Sbjct: 1587 LAPMAAPQTAILAPSPAPPLAPLPVLA-PSPGAAPVLASSQT---------PVPVMAPSS 1636
Query: 1052 GPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATE----- 1106
P ++L A VP P P +Q L +P P P LPS +T+
Sbjct: 1637 TPGTSLASASPVPAPTPVLAPSSTQTMLPAP-----------VPSP-LPSPASTQTLALA 1684
Query: 1107 -ASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPL 1165
A + SS SL G P P PT S P L V P + S+ P
Sbjct: 1685 PALAPTLGGSSPSQTLSLGTGNPQGPFPTQT-LSLTPASSL----VPTPAQTLSLAPGPP 1739
Query: 1166 LQPPE--NLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEE 1223
L P + +LA P P P+GP P+ TLA P A L +
Sbjct: 1740 LGPTQTLSLAPAPPLAPAS-PVGPAPAHTLTLA-----PASSSASLLAPASVQTLTLSPA 1793
Query: 1224 PPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPR--VSLSPHSPL----LSPKVASMDAKD 1277
P +LG A Q A A + T P VS S +PL +S S D D
Sbjct: 1794 PVPTLG----PAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPD 1849
Query: 1278 -LALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDE----DSLEEDSPRALGSG-----Q 1327
L L+ PP PPS S GP+ P DSLEE R Q
Sbjct: 1850 TLTLRSGPP---SPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQ 1906
Query: 1328 HSDSHGESSAELDEQDILAPQTVQCPAQAPAG 1359
S++HG + A + ++L T+ P +P G
Sbjct: 1907 LSEAHG-ALAPVYGTEVLDFCTLPQPVASPIG 1937
Score = 69.7 bits (169), Expect = 2e-11
Identities = 186/861 (21%), Positives = 286/861 (33%), Gaps = 117/861 (13%)
Query: 499 ATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLC 558
A +V A E D E P E +S + + E+L TP E ++
Sbjct: 2262 AEQVAELAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQL-TPIERYAMKFL 2320
Query: 559 PDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDL-TLPQDSAMTPPLPLQDT------ 611
S + + E +L + V AA QAKE++ LPQ+ P + +
Sbjct: 2321 EASLEEVSRE---ELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGG 2377
Query: 612 ---DLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668
A P T VS++ Q + TP + T ++ P + A
Sbjct: 2378 THRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARE--- 2434
Query: 669 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLT-LPQDSAMTPPLP 727
+P+ + P P A PV + V A +T LP +PP P
Sbjct: 2435 ------RVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPP 2488
Query: 728 LQDTDLSS-APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 786
Q SS A P A T A TPP S+P + ++
Sbjct: 2489 SQIPPCSSPACTPPPACT-------------PPPAHTPPPAQTCLVTPSSPLLLGPPSVP 2535
Query: 787 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD--SAMTP 844
+ L L + P L L+S A+ S+ + L P+D
Sbjct: 2536 ISASVTNLPL----GLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVE 2591
Query: 845 PLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPE----PL 900
LP+ + +LS P + E ++P AP + T T PE PL
Sbjct: 2592 ILPVSEKNLSLTPSAPSLTL-------EAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPL 2644
Query: 901 AVATPQTLQAEAGCA---PGTEPV-ATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALD 956
V+ L+ A P EP+ A +E+ EA P +PE+ + +
Sbjct: 2645 CVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTS 2704
Query: 957 QVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEA 1016
P+ + A P + + + + P G ++ L PGR +
Sbjct: 2705 SSATSSPEGPSPARPP---RRRTSADVEIRGQGTGRPGQPPGPKVLRKL--PGRLVTVVE 2759
Query: 1017 RAHTGDGAKPDSPQKETLEV---ENQQEGGLKPLAQEHGPRSA--LGGAREVPDAPPAAC 1071
+ TL E G + GP S+ +GG E AP ++
Sbjct: 2760 EKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEA--APSSSL 2817
Query: 1072 PEVSQARLLSPAREERGLSGKSTPE-------PTLPSAVATEASLDSCPESSVGAVSSLD 1124
P Q ++ E G++G +PE P AV P + +
Sbjct: 2818 PTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGR---PPKKNRSPADAG 2874
Query: 1125 RGCPDAPAPTSAPTSQQPEPVLG------LGSVEQPHEVPSV--LG-------TPLLQPP 1169
RG +AP+ T + +PV G V +P +P LG PLL P
Sbjct: 2875 RGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPV 2934
Query: 1170 ENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLG 1229
E +G+P D P+ PGT++ A E + P L
Sbjct: 2935 EKRRRGRPPKARDLPI------PGTISSAG------------DGNSESRTQPPPHPSPLT 2976
Query: 1230 LPPPQAGVQPAAAAVSGTTQPLGTGP--RVSLSPHSPLLSPKVASMDAKDL-ALQILPPC 1286
PP A A + TT + T P R P SP+ + + D + +L C
Sbjct: 2977 PLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESC 3036
Query: 1287 QVPPPSGPQSPAGPQGLSAPE 1307
+ PQ +G S+ E
Sbjct: 3037 GLGRRRQPQGQGESEGSSSDE 3057
Score = 59.3 bits (142), Expect = 3e-08
Identities = 113/481 (23%), Positives = 173/481 (35%), Gaps = 79/481 (16%)
Query: 911 EAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAG 970
EAG + + A+QE+ AL + P E+ A A+L++V +++ + A E
Sbjct: 2284 EAGRPGAEDEEMSRAEQEIA-ALVEQLTPIERYAMKFL---EASLEEVSREELKQAEEQV 2339
Query: 971 TPWAAQEDADSTLGMEALSLP---EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD 1027
AA++D D E LP E GAG+E + TG G
Sbjct: 2340 E--AARKDLDQAKE-EVFRLPQEEEEGPGAGDE---------------SSCGTGGGT--- 2378
Query: 1028 SPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREER 1087
+ + + + + G + + G R+ GA P + SPARE R
Sbjct: 2379 --HRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARE-R 2435
Query: 1088 GLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLD-------RGCPDAPAPTSAPTSQ 1140
P PT SA A +L P S+ +S+ + P P P+ P
Sbjct: 2436 VPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCS 2495
Query: 1141 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPV-----DRPLGPDPSAPGTL 1195
P P P T L+ P L G PS P+ + PLG P A
Sbjct: 2496 SPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCA 2555
Query: 1196 AGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGP 1255
A P + + SV E SL L PP+ + P A + ++
Sbjct: 2556 QALASP----------ESLELASVASSE-TSSLSLVPPK-DLLPVAVEILPVSE-----K 2598
Query: 1256 RVSLSPHSPLLSPKVASM----------DAKDLALQILPPCQVPPPSGPQSPAGPQGLSA 1305
+SL+P +P L+ + S+ A+ L +LP + P +S GL
Sbjct: 2599 NLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSES----NGLEL 2654
Query: 1306 PEQQEDEDSLEED-----SPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGG 1360
P ++ L+E + L + S E EL ++ AP T +P G
Sbjct: 2655 PPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGP 2714
Query: 1361 S 1361
S
Sbjct: 2715 S 2715
Score = 54.3 bits (129), Expect = 9e-07
Identities = 182/895 (20%), Positives = 284/895 (31%), Gaps = 193/895 (21%)
Query: 606 LPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATL 665
+PL++ SS P ++ EE + Q ++ L + E A A
Sbjct: 2212 MPLEEPSSSSVPS-------APEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQ 2264
Query: 666 VSQQAE--EGLTLPQDSAMTPPLP-LQDTDLSSAPKPVAAA----TLVSQQAEEGLTLPQ 718
V++ AE E P P +D ++S A + +AA T + + A + L
Sbjct: 2265 VAELAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASL 2324
Query: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT------- 771
+ L + + +A K + Q EE LPQ+ P + +
Sbjct: 2325 EEVSREELKQAEEQVEAARKDL------DQAKEEVFRLPQEEEEGPGAGDESSCGTGGGT 2378
Query: 772 --DLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 829
A P T VS++ Q + TP + T ++ P + A
Sbjct: 2379 HRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARE---- 2434
Query: 830 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQ 889
+P+ + P P A PV + PV A +T+ + +P P
Sbjct: 2435 -----RVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPS 2489
Query: 890 DTGPTSGPE---------------------------------------------PLAVAT 904
P S P PL +
Sbjct: 2490 QIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRP 2549
Query: 905 PQTLQAEAGCAPGTEPVATMAQQEVGE------------ALGPRPAPEEKNAALPTVP-- 950
L A+A +P + +A++A E A+ P E+ + P+ P
Sbjct: 2550 EAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSL 2609
Query: 951 --EPAALDQVQQDDPQPAAEAGTPWAAQEDAD---------------STLGMEALSLPEP 993
E ++ Q+ + +AE T E + S E L P
Sbjct: 2610 TLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLE 2669
Query: 994 ASGAGEEIAEALS------RPGREACLEARAHTGDGAKPDSPQ----------KETLEVE 1037
A EE+ EA + +P E A + + SP+ + + +VE
Sbjct: 2670 ADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVE 2729
Query: 1038 NQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEP 1097
+ +G +P Q GP + + P V + L+ R++RG + P
Sbjct: 2730 IRGQGTGRP-GQPPGP-------KVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGV 2781
Query: 1098 TLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEP----------VLG 1147
+ SA S+ S G SS G P AP+S+ + +P V G
Sbjct: 2782 SETSASPGSPSV----RSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTG 2837
Query: 1148 LGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAG---------- 1197
GS E + P ++ + +P D G D + TL G
Sbjct: 2838 GGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPG 2897
Query: 1198 -----AALPPLEP----------PAPCLCQDPQEDSVEDE---EPPGSLGLPPPQAGVQP 1239
A P LEP P P +P VE PP + LP P
Sbjct: 2898 PETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSA 2957
Query: 1240 AAAAVSGTTQPLGTGPRVS-LSPHSPLLSPKVASM--DAKDLALQILPPCQV--PPPSGP 1294
TQP P S L+P PLL A++ + + PP + PP P
Sbjct: 2958 GDGNSESRTQP---PPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNP 3014
Query: 1295 QSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQT 1349
SP Q P D S+ E LG + GES ++D P T
Sbjct: 3015 PSPRPSQ---LPVLDRDSTSVLESC--GLGRRRQPQGQGESEGSSSDEDGSRPLT 3064
Score = 45.8 bits (107), Expect = 3e-04
Identities = 82/302 (27%), Positives = 113/302 (37%), Gaps = 58/302 (19%)
Query: 13 PEADRPGP-RTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGAS 71
P A P P + L A++A+ L P A P L P+ P A P P A
Sbjct: 1560 PSAPNPAPAQASLLAPASSASQALA----TPLAPMAAPQTAILAPSPAPPLA-PLPVLAP 1614
Query: 72 WDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALL- 130
PG AP + P P++ P +L++ +P+PA P V+ + Q +L
Sbjct: 1615 ---SPGAAPVLASSQT---PVPVMAPSSTPGTSLASASPVPA---PTPVLAPSSTQTMLP 1665
Query: 131 --------SPRAART-----ALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPP 177
SP + +T AL GG + P + S G + P P TP
Sbjct: 1666 APVPSPLPSPASTQTLALAPALAPTLGGSS----PSQTLSLGTGNPQGPFPTQTLSLTPA 1721
Query: 178 S----TPTKT-TYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSP 232
S TP +T + A P GP L +PP +P+ A + +P
Sbjct: 1722 SSLVPTPAQTLSLAPGPPLGPTQTL---------SLAPAPPLAPASPVGPAPAHTLTLAP 1772
Query: 233 -SCSLSLLAPAEGLDFPSGWGLSPQ------GSMVDERELHPAGTPEPPSSESSLSADSS 285
S S SLLAPA LSP + L PA T P S SSL +S
Sbjct: 1773 ASSSASLLAPASVQTLT----LSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSAS 1828
Query: 286 SS 287
+
Sbjct: 1829 GA 1830
Score = 36.2 bits (82), Expect = 0.25
Identities = 61/262 (23%), Positives = 100/262 (38%), Gaps = 47/262 (17%)
Query: 198 RDSEAELRDELLDSPP------ASPSGSYITADGDSWASSPSCSLSLLAPAEGLDF--PS 249
R+ E L + L PP +SPS + + D D+ P EG + P
Sbjct: 326 REGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDG----------PEEGAEEEPPQ 375
Query: 250 GWGLSPQGSMVDERELHP-----------AGTPEPPSSESSLSADSSSSWGQEGHFFDLD 298
+ P S V +R P A E E +++A+ G+ H +L
Sbjct: 376 VLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLE-GEVDHAMELS 434
Query: 299 FLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAV----ADPDPGGDLAGEGEE 354
LA + L + L A S E+E+E+ V +D +P G + E
Sbjct: 435 ELARE-----GELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPP 489
Query: 355 DSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS------DSASYAEADDERLYSGE 408
S+S S+ D S E + + S+AS +S D+ S ++AD+E +
Sbjct: 490 QEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEE--EDD 547
Query: 409 PHAQATLLQDSVQKTEEESGGG 430
LL +++E ++G G
Sbjct: 548 DFGVEYLLARDEEQSEADAGSG 569
Score = 36.2 bits (82), Expect = 0.25
Identities = 167/729 (22%), Positives = 234/729 (32%), Gaps = 128/729 (17%)
Query: 44 ALTPGPSHLALTFLPSK-PGARPQPEGASWDAGPGGAPSAWAD------------PGEG- 89
A TPGP+ +++ LPS P P P G S P + P +G
Sbjct: 1264 APTPGPTPVSV--LPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGL 1321
Query: 90 GPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGE-----ETCQALLSPRAARTALRDQEG 144
P P L P + LPA L PR + T +P T +R
Sbjct: 1322 TPVPPLAPA-----PRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLK 1376
Query: 145 GHASPDPPPELCSQG--DLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEA 202
SP P + G L++ SP P S P S+P +P P S
Sbjct: 1377 LVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMP-----IPNSSPLASPVSSTV 1431
Query: 203 ELR---------DELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGL--DFPSGW 251
+ L +P ++P I+A AS P+ S+ P + P
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP 1491
Query: 252 GLSPQGSMVDERELHPAGTPEPPSSESS-------LSADSSSSWGQEGHFFDLDFLANDP 304
L+P G+ L G PS SS L A +SS G + +
Sbjct: 1492 SLAPSGASPSASAL-TLGLATAPSLSSSQTPGHPLLLAPTSSH--VPGLNSTVAPACSPV 1548
Query: 305 MIPAALL-----------PFQGSLIFQVEAVE---VTPLSPEEEEEEAVADPDPGGDLAG 350
++PA+ L P Q SL+ + TPL+P + A+ P P LA
Sbjct: 1549 LVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLA- 1607
Query: 351 EGEEDSTSASFLQSLSDLSITEGMDEAFAFRDD--TSAASSDSDSASYAEADDERLYSGE 408
L L+ + G A A S + S A A S
Sbjct: 1608 -------------PLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA------SPV 1648
Query: 409 PHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQEL---- 464
P L S Q A T++ A AP G+ SQ L
Sbjct: 1649 PAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLG--GSSPSQTLSLGTGN 1706
Query: 465 -ISEVTEEGLALGQESTATVTP-HTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAM 522
+ L+L S+ TP TL +APG P G +T S A A
Sbjct: 1707 PQGPFPTQTLSLTPASSLVPTPAQTLSLAPG----------PPLGPTQTLSLAPAPPLAP 1756
Query: 523 AMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDL----PSGRK 578
A P + L S +A L P +LTL P L L S +
Sbjct: 1757 ASPVGPAPAHTLTLAPASSSASLL-APASVQTLTLSPAPVPTLGPAAAQTLALAPASTQS 1815
Query: 579 PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDL----SSAPKPVAAATIVSQQAEEGL 634
P + A+ + A LP P+ + D S P P + AT
Sbjct: 1816 PASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGG------ 1869
Query: 635 TLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQ-DSAMTPPLPLQDTDL 693
P+ PP P L S + S++ E L + A+ P + D
Sbjct: 1870 --PRPRRQPPPPPRSPFYLDSLEEKRKRQR--SERLERIFQLSEAHGALAPVYGTEVLDF 1925
Query: 694 SSAPKPVAA 702
+ P+PVA+
Sbjct: 1926 CTLPQPVAS 1934
Score = 33.1 bits (74), Expect = 2.1
Identities = 44/168 (26%), Positives = 58/168 (34%), Gaps = 26/168 (15%)
Query: 1184 PLGPDPSAPGTLAGAALPPLEPPAPCL--------CQDPQEDSVEDEEPPGSLGLPP--P 1233
PLGP P P + P P P + + PPG + LPP P
Sbjct: 1018 PLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQP 1077
Query: 1234 QAGVQPAA-----AAVSGTTQPLGTGPRVSLSPHSPL---LSPKVASMDAKDLALQILPP 1285
+G P +SGT++P P +SL P P LSP + L +PP
Sbjct: 1078 NSGSLPQVLPSPLGVLSGTSRP--PTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPP 1135
Query: 1286 CQVPPP------SGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQ 1327
PP S + A + AP L D L SG+
Sbjct: 1136 GYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGE 1183
Score = 31.6 bits (70), Expect = 6.1
Identities = 63/263 (23%), Positives = 83/263 (31%), Gaps = 57/263 (21%)
Query: 90 GPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASP 149
GP P+ P G A T P+P L +++ L P AS
Sbjct: 1020 GPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIP--------------ASR 1065
Query: 150 DPPPEL---CSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRD 206
P P L S+P P P + S P T +L P P R S
Sbjct: 1066 PPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPT--PPAPVRLS------ 1117
Query: 207 ELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELH 266
PA P G S SLL P L P G+ P +
Sbjct: 1118 ------PAPPPG----------------SSSLLKP---LTVPPGYTFPPAAATTTSTTTA 1152
Query: 267 PAGT-----PEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQV 321
A T P P LS D + G + LA+ P A L FQ+
Sbjct: 1153 TATTTAVPAPTPAPQRLILSPDMQARL-PSGEVVSIGQLASLAQRPVANAGGSKPLTFQI 1211
Query: 322 EAVEVTPLSPEEEEEEAVADPDP 344
+ ++T L+ + + AV P P
Sbjct: 1212 QGNKLT-LTGAQVRQLAVGQPRP 1233
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 87.4 bits (215), Expect = 9e-17
Identities = 184/798 (23%), Positives = 271/798 (33%), Gaps = 110/798 (13%)
Query: 611 TDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATLVSQQ 669
T PKP V +A GL V TP Q ++S++PK A + +
Sbjct: 74 TKKKPTPKPP-----VVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP 128
Query: 670 A---------EEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 719
+ E LT+ +++ + T + S+ K + +Q E+ T +D
Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK--TSAKD 186
Query: 720 SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK- 778
A T + + T + A T + T P++ A T P T + SAP
Sbjct: 187 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTP---TTPKEPASTTPKEPTPTTIKSAPTT 243
Query: 779 -----PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 833
P + + E T ++ A T P T + P P + + E
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPA 302
Query: 834 LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGP 893
T P+ A T P T P P P E T P++ A TAP + P
Sbjct: 303 PTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KKPAP 358
Query: 894 TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPA 953
T+ EP A TP+ EP T +E PAP +A T EPA
Sbjct: 359 TTPKEP-APTTPK------------EPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTKEPA 404
Query: 954 ALD----QVQQDDPQP-AAEAGTPWAAQEDADSTLGMEALSLP-EPASGAGEEIAEALS- 1006
+P P + P +E A +T A + P EPA +E A +
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 464
Query: 1007 RPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDA 1066
+P E T P +P+K T P + A P+
Sbjct: 465 KPAPTTPKEPAPTTPKETAPTTPKKLT-------------------PTTPEKLAPTTPEK 505
Query: 1067 PPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRG 1126
P PE L EE + P PT P A A + P + +
Sbjct: 506 PAPTTPE----ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT---- 557
Query: 1127 CPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLA----KGQPSTPVD 1182
P PAPT+ P P G P+ TP P+ LA K ST D
Sbjct: 558 TPKEPAPTT-PKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCD 613
Query: 1183 RPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAA 1242
+P AP T G A + PAP ++P + + P +L P P +PA
Sbjct: 614 KP------APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT-TLKEPAPTTPKKPAPK 666
Query: 1243 AVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQG 1302
++ TT GP + S +PK + P + P P+ P++P
Sbjct: 667 ELAPTTT---KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP--KKPAPTTPETPPPTTS 721
Query: 1303 LSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDI-LAPQTVQCP-AQAPAGG 1360
+ E + SP +S E SAE + + +P+ P + PA
Sbjct: 722 EVSTPTTTKEPTTIHKSP--------DESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 773
Query: 1361 SEETIAKAKQSRSEKKAR 1378
E AK +E+ R
Sbjct: 774 KPEMTTTAKDKTTERDLR 791
Score = 68.6 bits (166), Expect = 5e-11
Identities = 137/573 (23%), Positives = 193/573 (33%), Gaps = 85/573 (14%)
Query: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATV----TPHTLQVAPGLQVEVATR 501
++AP T A + ++ + E +E T T P T + AP E A
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351
Query: 502 VTPQAGE---EETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLC 558
+ +E T +E A +PS E T + PT +E + T
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE---PAPTTTKSAPTTTKEPAPTTT 408
Query: 559 PDSPQNLKEEGGLDL--PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPL-PLQDTDLSS 615
+P KE P+ P A P+ K T P++ A T P P T
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKP 466
Query: 616 APKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLT 675
AP + E T P+++ T P L T P+ +A T + T
Sbjct: 467 AP---------TTPKEPAPTTPKETAPTTPKKLTPT----TPEKLAPTT----PEKPAPT 509
Query: 676 LPQDSA-MTPPLPLQDTDLSSAPK-PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDL 733
P++ A TP P T AP P AAA + E T P++ A T P T
Sbjct: 510 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAP--NTPKEPAPTTPKEPAPTTPKEPAPT-- 565
Query: 734 SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 793
PK A T + TL + + TP P APK +A T
Sbjct: 566 --TPKETAPTT---PKGTAPTTLKEPAPTTPKKP--------APKELAPTTTKE------ 606
Query: 794 LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL 853
P + P P + PK A T E T P++ A T P T L
Sbjct: 607 ---PTSTTCDKPAP-------TTPKGTAPTT----PKEPAPTTPKEPAPTTPKGTAPTTL 652
Query: 854 SSAPKPVAAATPVSQQAEEGLTLPQDSAMT---APLPLQDTGPTSGPEPLAVATPQTLQA 910
P P P ++ T S + AP ++T PT+ EP P T +
Sbjct: 653 KE-PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP----APTTPKK 707
Query: 911 EAGCAPGTEPVATMAQQEVGEALGP---RPAPEEKNAALPTVPEPAALDQVQQDDPQPAA 967
A P T P T P +P+E L P P AL+ ++ P
Sbjct: 708 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTT 767
Query: 968 E---AGTPWAAQEDADSTLGMEALSLPEPASGA 997
+ A P D T + + PE + A
Sbjct: 768 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 800
Score = 63.2 bits (152), Expect = 2e-09
Identities = 109/516 (21%), Positives = 161/516 (31%), Gaps = 59/516 (11%)
Query: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505
E AP T A + ++ + E +E T T P T+ P
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398
Query: 506 AGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNL 565
+E +T P P+ T E PT +E + T
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPT------------TTKEPAPTTPKEPAPTTPKKPAPTT 446
Query: 566 KEEGGLDLPSGRKPVAAATIVPRQAKEDL-TLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 624
+E P P P KE T P+++A T P L T
Sbjct: 447 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506
Query: 625 IVSQQAEEGLTLPQDSV-MTPPLPLQDTELSSAPKPVA--AATLVSQQA-----EEGLTL 676
+ E T P++ TP P T ++AP A T + A E T
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566
Query: 677 PQDSAMTPPL---------PLQDTDLSSAPKPVAAATLVSQQA----EEGLTLPQDSAMT 723
P+++A T P P T APK +A T + + T P+ +A T
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 626
Query: 724 PPL---------PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 774
P P T +AP + + + L + P D
Sbjct: 627 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686
Query: 775 SAPKPVAAATIVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 833
+ PK A T E T P+ A TP P T S P T + + +E
Sbjct: 687 TTPKETAPTT----PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE- 741
Query: 834 LTLPQDSAMTPPLPLQD---------TDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 884
+ P+ SA P L++ T +A KP T + E L ++ A
Sbjct: 742 -STPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 800
Query: 885 PLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
P ++T T+ + T T Q + T P
Sbjct: 801 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 836
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 87.4 bits (215), Expect = 9e-17
Identities = 184/798 (23%), Positives = 271/798 (33%), Gaps = 110/798 (13%)
Query: 611 TDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATLVSQQ 669
T PKP V +A GL V TP Q ++S++PK A + +
Sbjct: 115 TKKKPTPKPP-----VVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP 169
Query: 670 A---------EEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 719
+ E LT+ +++ + T + S+ K + +Q E+ T +D
Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK--TSAKD 227
Query: 720 SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK- 778
A T + + T + A T + T P++ A T P T + SAP
Sbjct: 228 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTP---TTPKEPASTTPKEPTPTTIKSAPTT 284
Query: 779 -----PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 833
P + + E T ++ A T P T + P P + + E
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPA 343
Query: 834 LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGP 893
T P+ A T P T P P P E T P++ A TAP + P
Sbjct: 344 PTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KKPAP 399
Query: 894 TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPA 953
T+ EP A TP+ EP T +E PAP +A T EPA
Sbjct: 400 TTPKEP-APTTPK------------EPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTKEPA 445
Query: 954 ALD----QVQQDDPQP-AAEAGTPWAAQEDADSTLGMEALSLP-EPASGAGEEIAEALS- 1006
+P P + P +E A +T A + P EPA +E A +
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 505
Query: 1007 RPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDA 1066
+P E T P +P+K T P + A P+
Sbjct: 506 KPAPTTPKEPAPTTPKETAPTTPKKLT-------------------PTTPEKLAPTTPEK 546
Query: 1067 PPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRG 1126
P PE L EE + P PT P A A + P + +
Sbjct: 547 PAPTTPE----ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT---- 598
Query: 1127 CPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLA----KGQPSTPVD 1182
P PAPT+ P P G P+ TP P+ LA K ST D
Sbjct: 599 TPKEPAPTT-PKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCD 654
Query: 1183 RPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAA 1242
+P AP T G A + PAP ++P + + P +L P P +PA
Sbjct: 655 KP------APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT-TLKEPAPTTPKKPAPK 707
Query: 1243 AVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQG 1302
++ TT GP + S +PK + P + P P+ P++P
Sbjct: 708 ELAPTTT---KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP--KKPAPTTPETPPPTTS 762
Query: 1303 LSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDI-LAPQTVQCP-AQAPAGG 1360
+ E + SP +S E SAE + + +P+ P + PA
Sbjct: 763 EVSTPTTTKEPTTIHKSP--------DESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 814
Query: 1361 SEETIAKAKQSRSEKKAR 1378
E AK +E+ R
Sbjct: 815 KPEMTTTAKDKTTERDLR 832
Score = 68.6 bits (166), Expect = 5e-11
Identities = 137/573 (23%), Positives = 193/573 (33%), Gaps = 85/573 (14%)
Query: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATV----TPHTLQVAPGLQVEVATR 501
++AP T A + ++ + E +E T T P T + AP E A
Sbjct: 333 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392
Query: 502 VTPQAGE---EETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLC 558
+ +E T +E A +PS E T + PT +E + T
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE---PAPTTTKSAPTTTKEPAPTTT 449
Query: 559 PDSPQNLKEEGGLDL--PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPL-PLQDTDLSS 615
+P KE P+ P A P+ K T P++ A T P P T
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKP 507
Query: 616 APKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLT 675
AP + E T P+++ T P L T P+ +A T + T
Sbjct: 508 AP---------TTPKEPAPTTPKETAPTTPKKLTPT----TPEKLAPTT----PEKPAPT 550
Query: 676 LPQDSA-MTPPLPLQDTDLSSAPK-PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDL 733
P++ A TP P T AP P AAA + E T P++ A T P T
Sbjct: 551 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAP--NTPKEPAPTTPKEPAPTTPKEPAPT-- 606
Query: 734 SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 793
PK A T + TL + + TP P APK +A T
Sbjct: 607 --TPKETAPTT---PKGTAPTTLKEPAPTTPKKP--------APKELAPTTTKE------ 647
Query: 794 LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL 853
P + P P + PK A T E T P++ A T P T L
Sbjct: 648 ---PTSTTCDKPAP-------TTPKGTAPTT----PKEPAPTTPKEPAPTTPKGTAPTTL 693
Query: 854 SSAPKPVAAATPVSQQAEEGLTLPQDSAMT---APLPLQDTGPTSGPEPLAVATPQTLQA 910
P P P ++ T S + AP ++T PT+ EP P T +
Sbjct: 694 KE-PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP----APTTPKK 748
Query: 911 EAGCAPGTEPVATMAQQEVGEALGP---RPAPEEKNAALPTVPEPAALDQVQQDDPQPAA 967
A P T P T P +P+E L P P AL+ ++ P
Sbjct: 749 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTT 808
Query: 968 E---AGTPWAAQEDADSTLGMEALSLPEPASGA 997
+ A P D T + + PE + A
Sbjct: 809 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 841
Score = 63.2 bits (152), Expect = 2e-09
Identities = 109/516 (21%), Positives = 161/516 (31%), Gaps = 59/516 (11%)
Query: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505
E AP T A + ++ + E +E T T P T+ P
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 439
Query: 506 AGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNL 565
+E +T P P+ T E PT +E + T
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPT------------TTKEPAPTTPKEPAPTTPKKPAPTT 487
Query: 566 KEEGGLDLPSGRKPVAAATIVPRQAKEDL-TLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 624
+E P P P KE T P+++A T P L T
Sbjct: 488 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547
Query: 625 IVSQQAEEGLTLPQDSV-MTPPLPLQDTELSSAPKPVA--AATLVSQQA-----EEGLTL 676
+ E T P++ TP P T ++AP A T + A E T
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607
Query: 677 PQDSAMTPPL---------PLQDTDLSSAPKPVAAATLVSQQA----EEGLTLPQDSAMT 723
P+++A T P P T APK +A T + + T P+ +A T
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 667
Query: 724 PPL---------PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 774
P P T +AP + + + L + P D
Sbjct: 668 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727
Query: 775 SAPKPVAAATIVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 833
+ PK A T E T P+ A TP P T S P T + + +E
Sbjct: 728 TTPKETAPTT----PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE- 782
Query: 834 LTLPQDSAMTPPLPLQD---------TDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 884
+ P+ SA P L++ T +A KP T + E L ++ A
Sbjct: 783 -STPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 841
Query: 885 PLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
P ++T T+ + T T Q + T P
Sbjct: 842 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 877
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 86.3 bits (212), Expect = 2e-16
Identities = 230/1035 (22%), Positives = 347/1035 (33%), Gaps = 173/1035 (16%)
Query: 363 QSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQK 422
Q+L + ++ A R+ A + E D +R GEP + +
Sbjct: 908 QTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQR---GEPEGGSQDQKGQASS 964
Query: 423 TEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTAT 482
E G GA L G S V + Q+ RG+ +S R+ ++GL
Sbjct: 965 PTPEPGVGAGDLP---GPTSAPVPSGSQSGGRGSPVSPRRH------QKGLL-------- 1007
Query: 483 VTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVT 542
++ P E A+R+ E S QES +P T
Sbjct: 1008 ----NCKMPPA---EKASRIRAA----EKVSRGDQESPDACLPP---------------T 1041
Query: 543 AEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAM 602
+ P P P P N + + L P P+ + I P K T S
Sbjct: 1042 VPEAPAP---------PQKPLNSQSQKHLAPPPLLSPLLPS-IKPTVRK---TRQDGSQE 1088
Query: 603 TPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAA 662
P PL PKP I ++++ P S P P T PKP +
Sbjct: 1089 APEAPLSSELEPFHPKP----KIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQ 1144
Query: 663 ATLVSQQAEEGLTLPQDSAMTPP--LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AT S+ + P+ T P P TD +P + T +++ + P+
Sbjct: 1145 ATR-SRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTR-GRKSRSSVKTPETV 1202
Query: 721 AMTPP--LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP--LPLQDTDLSSA 776
T P TD +P + AT ++ + P+ T P P TD
Sbjct: 1203 VPTALELQPSTSTDRPVTSEPTSQATR-GRKNRSSVKTPEPVVPTAPELQPSTSTDQPVT 1261
Query: 777 PKPVAAATIVSQQAEEGLTLPQDSAMTPP--LPLQDTDLSSAPKPVAAATIVSQQAEEGL 834
+P AT ++ + P+ T P P TD PKP + T S+ +
Sbjct: 1262 SEPTYQATR-GRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTR-SRTNMSSV 1319
Query: 835 TLPQDSAMTPPLPLQ---DTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPL--PLQ 889
P+ T P LQ TD PKP + T S+ + P+ + AP P
Sbjct: 1320 KTPETVVPTAP-ELQISTSTDQPVTPKPTSRTTR-SRTNMSSVKNPESTVPIAPELPPST 1377
Query: 890 DTGPTSGPEPLAVATPQTLQAEAGCAPGT---------------EPVATMAQQEVGEALG 934
T PEP + AT +G P T +PV +
Sbjct: 1378 STEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRT 1437
Query: 935 PRPAPEEKNAALPTVPE---PAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLP 991
R + + +PT PE + DQ +P A G + T+ A L
Sbjct: 1438 NRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQ 1497
Query: 992 EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEH 1051
AS +E SR R + T + P +P+ + +Q P+ E
Sbjct: 1498 ASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQ------PVTPEP 1551
Query: 1052 GPRSALGGARE---------VPDAPPAACPEVSQARLLSPAREERGL------SGKSTPE 1096
R+ G VP AP P S+ +L++P R S TPE
Sbjct: 1552 TSRATRGRTNRSSVKTPESIVPIAPELQ-PSTSRNQLVTPEPTSRATRCRTNRSSVKTPE 1610
Query: 1097 PTLPSAV----ATEASLDSCPESSVGAV------SSLDRGCPDAPAPTS----APTSQQP 1142
P +P+A T P+ + A SS+ P PA + PT Q
Sbjct: 1611 PVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSV 1670
Query: 1143 EP-VLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSA---------- 1191
P + G + +V P+ PE Q D+P+ P+P
Sbjct: 1671 TPEAIAQGGQSKTLRSSTVRAMPVPTTPEF----QSPVTTDQPISPEPITQPSCIKRQRA 1726
Query: 1192 ---PGTLAGA-----ALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPP-PQAGVQPAAA 1242
PG+LA PLEP + ++ + +V E ++ P PQ P A
Sbjct: 1727 AGNPGSLAAPIDHKPCSAPLEPKSQA-SRNQRWGAVRAAESLTAIPEPASPQLLETPIHA 1785
Query: 1243 AVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQG 1302
+ +P G S +P L PK + + LA PP Q P G S
Sbjct: 1786 SQIQKVEPAGR------SRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQK---- 1835
Query: 1303 LSAPEQQEDEDSLEE 1317
+ ++E+ED+ E+
Sbjct: 1836 -TVIIKEEEEDTAEK 1849
Score = 70.1 bits (170), Expect = 2e-11
Identities = 170/812 (20%), Positives = 274/812 (33%), Gaps = 103/812 (12%)
Query: 487 TLQVAPGLQVEVATRVTPQAG--EEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAE 544
T+ G+ E A RV P+ G E ET+ + + + +G + ++ + +
Sbjct: 809 TVDKVMGIPKETAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARD 868
Query: 545 KLPTPQEETSLTLCPDSP-QNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMT 603
++ + P+ ++LK E K V T+ + + ++ P +
Sbjct: 869 TQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANREC 928
Query: 604 PPLPLQDTDLSSAPKPVAAATIVSQQAE-EGLTLPQDSVMTPPLPLQDTELSSAPKPVAA 662
P L++ PK + +Q+ E EG + Q + P P P P +A
Sbjct: 929 DPAELEE----KVPKVILERD--TQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSA 982
Query: 663 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP--VAAATLVSQQAEEG--LTLPQ 718
V ++ G S L + + A K + AA VS+ +E LP
Sbjct: 983 P--VPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPP 1040
Query: 719 DSAMTPPLPLQDTDLSS----APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 774
P P + + S AP P+ + L S + T S P PL
Sbjct: 1041 TVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEP 1100
Query: 775 SAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGL 834
PKP I ++++ P SA P P T PKP + AT S+ +
Sbjct: 1101 FHPKP----KIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR-SRTNRSSV 1155
Query: 835 TLPQDSAMTPP--LPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTG 892
P+ T P P TD +P + T +++ + P+ TA L LQ +
Sbjct: 1156 KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTR-GRKSRSSVKTPETVVPTA-LELQPST 1213
Query: 893 PTSGP---EPLAVATP--------QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEE 941
T P EP + AT +T + AP +P +T Q V +
Sbjct: 1214 STDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQP-STSTDQPVTSEPTYQATRGR 1272
Query: 942 KNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEI 1001
KN + PEP + TP S M ++ PE E
Sbjct: 1273 KNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPE- 1331
Query: 1002 AEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAR 1061
L+ T P + T N ++ P S + A
Sbjct: 1332 ------------LQISTSTDQPVTPKPTSRTTRSRTN--------MSSVKNPESTVPIAP 1371
Query: 1062 EVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVS 1121
E+P + P + + + SGK TPE +P+A E S +
Sbjct: 1372 ELPPSTSTEQPVTPEPTSRATRGRKNRSSGK-TPETLVPTAPKLEPSTST---------- 1420
Query: 1122 SLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPV 1181
D P T PTSQ SV+ P V V P LQP ST
Sbjct: 1421 -------DQPV-TPEPTSQATRGRTNRSSVKTPETV--VPTAPELQP---------STST 1461
Query: 1182 DRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQ-EDSVEDEEPPGSLGLPPPQAGVQPA 1240
D+P+ P+P++ T ++ P + P+ + S ++P S +P
Sbjct: 1462 DQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTS----------EPT 1511
Query: 1241 AAAVSGTTQPLGTGPRVSLSPHSPLLSPKVAS 1272
+ G ++ P +P L P ++
Sbjct: 1512 SRTTRGRKNRSSVKTPETVVPAAPELQPSTST 1543
Score = 57.0 bits (136), Expect = 1e-07
Identities = 185/904 (20%), Positives = 302/904 (33%), Gaps = 150/904 (16%)
Query: 470 EEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQP-S 528
EEG +L A V L E A V Q E + G A + P S
Sbjct: 582 EEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPIS 641
Query: 529 QEGISEILGQESVTAE---------KLPTPQE-ETSLTLCPDSPQNLKEEGGLDLPSGRK 578
+E +++++ E ++PT +E E + DS N + LDL + +
Sbjct: 642 RENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQC 701
Query: 579 PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 638
+ + Q+ ED Q +TPP L + S Q L P
Sbjct: 702 FLENQGLEAVQSMEDEPT-QAFMLTPPQELGPSHCSF-------------QTTGTLDEPW 747
Query: 639 DSVMTPPLPLQDTELSSAPK-----PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDL 693
+ + T P L+++E S L +A G P+ T P+ +Q
Sbjct: 748 EVLATQPFCLRESEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGR 807
Query: 694 SSAPKPVAAATLVSQQA--EEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAE 751
+ K + +++ E G P + LP + TD++ E
Sbjct: 808 QTVDKVMGIPKETAERVGPERG---PLERETEKLLPERQTDVTG---------------E 849
Query: 752 EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDT 811
E LT + L +DT + K +A+ ++ E L + + T
Sbjct: 850 EELTKGKQDREQKQLLARDTQRQESDKNGESAS--PERDRESLKVEIE-----------T 896
Query: 812 DLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAE 871
K V T+ S+ E + P + P L++ PK + +Q+ E
Sbjct: 897 SEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEE----KVPKVILERD--TQRGE 950
Query: 872 -EGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVG 930
EG + Q ++P P G P P + P Q+ +P V+ Q+
Sbjct: 951 PEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSP----VSPRRHQK-- 1004
Query: 931 EALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL 990
L + P EK + + + + DQ D P P Q+ +S + L+
Sbjct: 1005 GLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQ-SQKHLAP 1063
Query: 991 PEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQE 1050
P S I + + ++ EA P++P LE P +
Sbjct: 1064 PPLLSPLLPSIKPTVRKTRQDGSQEA---------PEAPLSSELEP-------FHPKPKI 1107
Query: 1051 HGPRSALGGAREVPDAPPAACPEVSQARLLSP------AREERGLSGKSTPEPTLPSAVA 1104
+S+ A P P S A+ ++P R S TPEP +P+A
Sbjct: 1108 RTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPE 1167
Query: 1105 TEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEV-PSVLGT 1163
+ S + D P TS PTSQ SV+ P V P+ L
Sbjct: 1168 LQPSTST-----------------DQPV-TSEPTSQVTRGRKSRSSVKTPETVVPTALEL 1209
Query: 1164 PLLQPPENLAKGQPSTPVDRPLGPDPSAPGT-----LAGAALP-PLEPPAPCLCQDPQED 1217
QPST DRP+ +P++ T + P P+ P AP L D
Sbjct: 1210 ------------QPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTD 1257
Query: 1218 SVEDEEPP----------GSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRV----SLSPHS 1263
EP S+ P P P + T +P+ P S + S
Sbjct: 1258 QPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMS 1317
Query: 1264 PLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRAL 1323
+ +P+ A +L + V P ++ +S+ + E + + P +
Sbjct: 1318 SVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPST 1377
Query: 1324 GSGQ 1327
+ Q
Sbjct: 1378 STEQ 1381
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 83.2 bits (204), Expect = 2e-15
Identities = 141/568 (24%), Positives = 201/568 (35%), Gaps = 53/568 (9%)
Query: 698 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA-PKPVAAATLVSQQAEEGLTL 756
K V A EE + + Q + T +P L +A P P ++ + A EG +
Sbjct: 812 KQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV 871
Query: 757 PQDSAMTPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 812
A P P +D ++S + V AA + A E T+P + P
Sbjct: 872 V---AALVPFPHEDILVASIVSLEEEDVTAAAV---SAPERATVPAVTVSVPEGTAAVAA 925
Query: 813 LSS----APKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQ 868
+SS AP AA T A G + P+ +A+ +P+ + D + PV AT V
Sbjct: 926 VSSPEETAPAVAAAITQEGMSAVAGFS-PEWAALAITVPITEED-GTPEGPVTPATTVHA 983
Query: 869 QAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQE 928
E P +A+ P + P + AV TP+ + A P E + A
Sbjct: 984 PEE-----PDTAAVRVSTPEEPASPAA-----AVPTPEEPTSPAAAVPTPEEPTSPAA-- 1031
Query: 929 VGEALGPRPAPEEKNAALPTVPEP---AALDQVQQDDPQPAAEAGTPWAAQEDADSTLGM 985
A+ P P AA+PT EP AA ++ PAA TP A +
Sbjct: 1032 ---AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
Query: 986 EALSLPEPASGAGEEI---AEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEG 1042
E + P A EE A A+ P A A T P+ P V +E
Sbjct: 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT-----PEEPASPAAAVPTPEEP 1143
Query: 1043 GLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKST-PEPTLPS 1101
P P + A VP +A P A + +PA + +T EPT P+
Sbjct: 1144 AF-PAPAVPTPEESASAAVAVPTPEESASPA---AAVPTPAESASFAAVVATLEEPTSPA 1199
Query: 1102 A-VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1160
A V T A++ + E +S+ + PA +A S EP +V E S
Sbjct: 1200 ASVPTPAAMVATLEEFTSPAASVPTS--EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSS 1257
Query: 1161 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220
L PE L+ S P +A L A P P P + P
Sbjct: 1258 AAAVLT--PEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPT 1315
Query: 1221 DEEPPGSLGLPPPQAGVQPAAAAVSGTT 1248
E P PP V P G +
Sbjct: 1316 PEVPAIPAAAVPPMEEVSPIGVPFLGVS 1343
Score = 83.2 bits (204), Expect = 2e-15
Identities = 140/587 (23%), Positives = 208/587 (35%), Gaps = 100/587 (17%)
Query: 658 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA-PKPVAAATLVSQQAEEGLTL 716
K V A EE + + Q + T +P L +A P P ++ + A EG +
Sbjct: 812 KQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV 871
Query: 717 PQDSAMTPPLPLQDTDLSSAPK-PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS 775
A P P +D ++S T + A E T+P + P +SS
Sbjct: 872 V---AALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSS 928
Query: 776 ----APKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 831
AP AA T A G + P+ +A+ +P+ + D + PV AT V E
Sbjct: 929 PEETAPAVAAAITQEGMSAVAGFS-PEWAALAITVPITEED-GTPEGPVTPATTVHAPEE 986
Query: 832 EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDT 891
P +A+ P + P AAA P ++ P A P P + T
Sbjct: 987 -----PDTAAVRVSTPEE-------PASPAAAVPTPEE-------PTSPAAAVPTPEEPT 1027
Query: 892 GPTSGPEP--------LAVATPQTLQAEAGCAP----GTEPVATM-AQQEVGEALGPRPA 938
P + P AV TP+ + A P T P A + +E P
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1087
Query: 939 PEEKN---AALPTVPE---PAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPE 992
PEE AA+PT E PAA ++ PAA TP A + E + P
Sbjct: 1088 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA 1147
Query: 993 PASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHG 1052
PA EE A A +P+ E+ P E
Sbjct: 1148 PAVPTPEESASA------------------AVAVPTPE------ESASPAAAVPTPAESA 1183
Query: 1053 PRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSC 1112
+A+ E P +P A+ P + + EE S P P+++A S
Sbjct: 1184 SFAAVVATLEEPTSPAASVPTPA---AMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE 1240
Query: 1113 PESSVGAVSSLDRGCPDAPA----------PTSAPTSQQP-EPVLGLGSVEQPHEVPSVL 1161
P S AV +L+ A A S PT ++P P + ++E+P + +
Sbjct: 1241 PTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAV 1300
Query: 1162 GTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAP 1208
TP + P+ V P P P + AA+PP+E +P
Sbjct: 1301 PTPEV-------AAIPAASV-----PTPEVP-AIPAAAVPPMEEVSP 1334
Score = 58.2 bits (139), Expect = 6e-08
Identities = 109/496 (21%), Positives = 177/496 (35%), Gaps = 84/496 (16%)
Query: 922 ATMAQQEVGEALGPRPAPEEKNAALPTVPEP------AALDQVQQDDPQPAA-----EAG 970
A + E G ++ PAPE VP P A++ ++++D AA A
Sbjct: 849 AALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERAT 908
Query: 971 TPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD--- 1027
P + T + A+S PE + A +A A+++ G A G P+
Sbjct: 909 VPAVTVSVPEGTAAVAAVSSPEETAPA---VAAAITQEGMSAVA--------GFSPEWAA 957
Query: 1028 -SPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREE 1086
+ E + EG + P H P P+ + R+ +P EE
Sbjct: 958 LAITVPITEEDGTPEGPVTPATTVHAPEE----------------PDTAAVRVSTP--EE 999
Query: 1087 RGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQP-EPV 1145
+ P P P++ A P S AV + P +PA + PT ++P P
Sbjct: 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEE--PTSPA-AAVPTPEEPTSPA 1056
Query: 1146 LGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALP-PLE 1204
+ + E+P + + TP +P++P P P P T AA+P P E
Sbjct: 1057 AAVPTPEEPTSPAAAVPTP----------EEPTSPAAAV--PTPEEP-TSPAAAVPTPEE 1103
Query: 1205 PPAPCLCQDPQED------SVEDEEPPGS--LGLPPPQAGVQPAAAA----VSGTTQPLG 1252
P +P E+ +V E P S +P P+ PA A S +
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163
Query: 1253 TGPRVSLSPHSPLLSPKVASMDAKDLAL---QILPPCQVPPPSGPQSPAGPQGLSAPEQQ 1309
P S SP + + +P ++ A +A P VP P+ A + ++P
Sbjct: 1164 PTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA--MVATLEEFTSPAAS 1221
Query: 1310 EDEDSLEEDSPRALGSGQHSDSHGESSAELDEQD-----ILAPQTVQCPAQAPAGGSEET 1364
A+ + + S + L+E +L P+ + PA + E
Sbjct: 1222 VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA 1281
Query: 1365 IAKAKQSRSEKKARKA 1380
A S E+ A A
Sbjct: 1282 SPAAAVSNLEEPASPA 1297
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 81.6 bits (200), Expect = 5e-15
Identities = 172/772 (22%), Positives = 264/772 (34%), Gaps = 121/772 (15%)
Query: 572 DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631
D P +A + +VP + +P A P +P+ D P A +VS +
Sbjct: 334 DSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASA 393
Query: 632 EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691
+ +P P + + + P A + L+ +G +P +A P +P+
Sbjct: 394 DSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPA 453
Query: 692 D-----LSSAPKPVAAAT-----LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 741
D ++SA PV T LV +G +P SA P P+ D P A
Sbjct: 454 DTPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPA 513
Query: 742 AATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSA 801
+ + + L +P A +P L + + + P A + IV G +P SA
Sbjct: 514 DSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSA 573
Query: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861
+P +P+ D P A + +V + L A +P +P+ D PV
Sbjct: 574 DSPFVPVIPADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPAD-----SPVV 628
Query: 862 AATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTE-- 919
TP +G +P SA + +P+ T +P+ TP AE+ P T+
Sbjct: 629 PVTPA-----DGPVVPVASADSPFVPV-----TPADDPIVSVTP----AESPAIPVTQAD 674
Query: 920 -PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQED 978
PV + + RP A VP AA D + P A TP +
Sbjct: 675 SPVVPVTSAD-------RPVIPVTTADGRIVPVTAAGDPI-----VPVTPADTPGSPVTS 722
Query: 979 ADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVEN 1038
AD + P + A P +P +
Sbjct: 723 ADGPV--------VPVTSADSPFV-----------------------PVTPPDGPVVPVT 751
Query: 1039 QQEGGLKPLAQEHGP----RSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKST 1094
+G + P++ GP SA G V A P V+ A PA
Sbjct: 752 SADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVP-VTPADTNGPAVPVTSADSPFV 810
Query: 1095 P-----EPTLPSAVATEASLDSCP-ESSVGAVSSLDRGC-----PDAPAPTSAPTSQQPE 1143
P P +P A + + P +SS V S D D P + T
Sbjct: 811 PVIPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVV 870
Query: 1144 PVLGLGSVEQPHEVPSVLGTPL---------LQPPENLAKGQPSTPVDRPLGPDPSA--- 1191
PV + + P + PL + PP++L P TP D P+ P SA
Sbjct: 871 PVFPVNCILVPAFADETV-VPLNPADSPVIPVTPPDDLV--VPVTPTDCPVAPVTSADCP 927
Query: 1192 --PGTLAGAALPPL-EPPAPCLCQDPQEDSVEDEEPPGS--LGLPPPQAGVQPAAAAVSG 1246
P T A + P+ P + P +D + P S + + P V P A+A S
Sbjct: 928 VVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVSVTPADGPVVPVASADS- 986
Query: 1247 TTQPLGTGPRVSLSP-HSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1297
P V ++P P++S A A + P V P SP
Sbjct: 987 --------PFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSP 1030
Score = 81.6 bits (200), Expect = 5e-15
Identities = 175/780 (22%), Positives = 260/780 (33%), Gaps = 113/780 (14%)
Query: 572 DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631
D P +A + VP + +P A P +P+ D P A IVS
Sbjct: 604 DSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADDPIVSVTPA 663
Query: 632 EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691
E +P +P +P+ + P A +V A +P A TP P+
Sbjct: 664 ESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSA 723
Query: 692 D-----LSSAPKPVAAAT-----LVSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSA 736
D ++SA P T +V + +G P SA P +P+ D +SSA
Sbjct: 724 DGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSA 783
Query: 737 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL 796
PV T G +P SA +P +P+ D P A IV + +
Sbjct: 784 DGPVVPVTPAD---TNGPAVPVTSADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFV 840
Query: 797 PQDSAMTPPLPL----------QDTDLSSAPKPVAAATIVSQQAEEGLT--LPQDS---A 841
P SA +P +P+ TD+ P +V A+E + P DS
Sbjct: 841 PVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIP 900
Query: 842 MTPP----LPLQDTD-----LSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTG 892
+TPP +P+ TD ++SA PV TP A+ P +A +P
Sbjct: 901 VTPPDDLVVPVTPTDCPVAPVTSADCPVVPVTPADSPAD-----PVTAADGPVVPF---- 951
Query: 893 PTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEP 952
T +P+ TP P PV +A +A P VP
Sbjct: 952 -TPADDPIVPVTPAD-SPVVSVTPADGPVVPVA-----------------SADSPFVPVT 992
Query: 953 AALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREA 1012
A D + P A +P ADS + P + A ++ + GR
Sbjct: 993 PADDPIVSVTP-----AESPAIPVTQADSPV--------VPVTSADRPVSPVTTADGRIV 1039
Query: 1013 CLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACP 1072
+ A GD P +P +G + P+ P VP PP P
Sbjct: 1040 PVTA---AGDPIVPVTPADTPGSPVTSADGPVVPVTSADSP--------FVPVTPPDG-P 1087
Query: 1073 EVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPA 1132
V P G P + VA +S D V V+ D P P
Sbjct: 1088 VVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSAD----GPVVPVTPAD--SPFIPV 1141
Query: 1133 PTS----APTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPD 1188
T+ P + PVL + + P + +P++ P P + D P P
Sbjct: 1142 TTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPV 1201
Query: 1189 PSAPGTL-----AGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLP--PPQAGVQPAA 1241
A G + + P+ P L D +D V S +P P + V P
Sbjct: 1202 IPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVPVT 1261
Query: 1242 AAVSGTTQPL-GTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGP 1300
+A S P + ++P P++S A ++ P V P P P
Sbjct: 1262 SADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPVVPVTP 1321
Score = 79.7 bits (195), Expect = 2e-14
Identities = 171/792 (21%), Positives = 263/792 (33%), Gaps = 90/792 (11%)
Query: 560 DSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTD-----LS 614
DSP D P A +VP + + L +P A P +P+ D +S
Sbjct: 1712 DSPVVPVTSADTDSPGSPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVS 1771
Query: 615 SAPKPVAAAT-----IVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQ 669
SA PV T +V + T+P +P +P+ P A + V
Sbjct: 1772 SADGPVVPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVI 1831
Query: 670 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 729
+GL + S +P+ TD P +A +VS + +P A +P + +
Sbjct: 1832 PADGLVVLDSSTDVLVVPVSPTDGILVP-DLADDPVVSVTIADSPVIPVTPADSPVVLVT 1890
Query: 730 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 789
D P +V + +P P +P+ D P A + IVS
Sbjct: 1891 PADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVT 1950
Query: 790 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQ 849
+ P A +P +P+ D P A +V +G +P A +P +P+
Sbjct: 1951 PADSPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVT 2010
Query: 850 DTD-----LSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVAT 904
TD ++SA PV PV+ + P DS + P D P V
Sbjct: 2011 PTDSPVVPVTSADSPV---IPVTADSPFVPVTPADSPVIPVTPPDDLVVPVTPIDCPV-V 2066
Query: 905 PQTLQ--AEAGCAPGTEPVATMAQQE-----VGEALGP-RPAPEEKNAALPTVPEPAALD 956
P TL P PV + + V A P P + +P P + +
Sbjct: 2067 PVTLVDCPVVSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIV 2126
Query: 957 QVQQDDPQ--PAAEAGTPWAAQEDADSTL----GMEALSLP-EPASGAGEEIAEALSRPG 1009
V D P A +P + ADS + + + +P PA G + A S
Sbjct: 2127 SVTPADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTPADGPVIPVTPAES--- 2183
Query: 1010 REACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPA 1069
A P +P + + + P+ P + PPA
Sbjct: 2184 -------------PAIPVTPADSPVVPVTPADDPVVPVTPADSP---------IVPVPPA 2221
Query: 1070 ACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPD 1129
+ P V +P G P + S + DS P V S
Sbjct: 2222 SDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPGDS-PVVPVTPADSPVFPVTS 2280
Query: 1130 APAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDP 1189
A P P + +PV + + P S +P++ P TP + P+ P P
Sbjct: 2281 ADGPV-FPVTLADDPVFPVTPADDPIFPVSPADSPVV----------PVTPANIPVVPVP 2329
Query: 1190 SA-----PGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAV 1244
A P T AG+ P+ P + D D + P G+P P P +
Sbjct: 2330 PANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPTD-GIPVPDLADDPVVSVT 2388
Query: 1245 SGTTQPLGTGPRVS-LSPHSPLLSP--KVASMDAKDLALQILPPCQVPPPSGPQSPAGP- 1300
+ + + P S + P +P P V S+D+ P V P P P P
Sbjct: 2389 TSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDS--------PVVPVTPADSPVIPVTPA 2440
Query: 1301 QGLSAPEQQEDE 1312
L P D+
Sbjct: 2441 DSLVVPATPADD 2452
Score = 79.3 bits (194), Expect = 3e-14
Identities = 185/836 (22%), Positives = 282/836 (33%), Gaps = 125/836 (14%)
Query: 548 TPQEETSLTLCPDS----PQNLKEEGGLDLPSGRKPVAAAT-----IVPRQAKEDLTLPQ 598
TP ++ +++ P P + + + S +PV+ T IVP A D +P
Sbjct: 992 TPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPV 1051
Query: 599 DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPK 658
A TP P+ D P A + V +G +P S P P+ + P
Sbjct: 1052 TPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPV 1111
Query: 659 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQ 718
A + + +G +P A +P +P+ D P A + ++S + +P
Sbjct: 1112 TSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPV 1171
Query: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778
A +P +P+ + P A + V +GL + S +P+ TD P
Sbjct: 1172 TPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVP- 1230
Query: 779 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAAT----IVSQQ 829
+A +VS + +P A +P +P+ D ++ A PV T +VS
Sbjct: 1231 DLADDPVVSVTIADSPVIPVTPADSPVVPVTSADSPVVPVTPADSPVILVTPVGPVVSVT 1290
Query: 830 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQ 889
+G + +A +P +P ++SA PV TP +G +P SA + +P+
Sbjct: 1291 TADGPVVLVSTADSPVIP-----VTSADSPVVPVTPA-----DGPVVPVTSADSPFVPV- 1339
Query: 890 DTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTV 949
T +P+ TP P P + + P +A P +
Sbjct: 1340 ----TPADDPIVPVTPAD-SPIVSVTPAESPAIPVTPAD-------SPVVPVTSADSPLI 1387
Query: 950 PEPAALDQVQQDDPQ-----PAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEA 1004
P A +V P P A TP + AD + P + AG+ I
Sbjct: 1388 PLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTSADGPV--------VPVTPAGDPIVPV 1439
Query: 1005 --LSRPGREACLE----ARAHTGDG-AKPDSPQKETLEVENQQEGGLKPLAQEHGPRSAL 1057
PG T DG P SP + +G + P+ P +
Sbjct: 1440 TPADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVTSADGPVVPVTPADSPFIPV 1499
Query: 1058 GGARE--VPDAP---------PAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATE 1106
A + VP P PA P V P P VA +
Sbjct: 1500 TTADDPIVPVTPADSPVVPVTPADIPVVPVTPANGPVIHVTSADCPFVPVIPADGLVALD 1559
Query: 1107 ASLD---------------SCPESSVGAVSSLDRG-CPDAPA-PTSAPTSQQPEPVLGLG 1149
+S D + V +V+ D P PA T P + PV+ +
Sbjct: 1560 SSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVT 1619
Query: 1150 SVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPC 1209
SV ++P V TP P P TPVD P+ A G++ +P P
Sbjct: 1620 SV----DIPVVPVTPANGPV------APVTPVDDPVVSVNPADGSV----VPVTSADCPV 1665
Query: 1210 LCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSL---------- 1259
+ P + V P S +P A P S + + P S
Sbjct: 1666 VPVTPADGLVVPVTPADSPIVPVTPAD-SPVVLVTSADSPVIPVTPADSPVVPVTSADTD 1724
Query: 1260 SPHSPLLS---PKVASMDAKDLALQILPPCQVPPPSGPQSP-AGPQGLSAPEQQED 1311
SP SP+ S P V A L P V P GP P G AP D
Sbjct: 1725 SPGSPVTSADGPVVPVTSADSL------PVPVTPADGPVVPVTSADGPVAPVSSAD 1774
Score = 73.9 bits (180), Expect = 1e-12
Identities = 168/768 (21%), Positives = 255/768 (33%), Gaps = 89/768 (11%)
Query: 585 IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP 644
+VP +DL P A +P +P+ D P A +V + G +P +P
Sbjct: 88 VVPVTPADDLVFPVTPADSPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSP 147
Query: 645 PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 704
P+ + P A + + + P A +P P+ D ++ P A
Sbjct: 148 VFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLFPVTPADSAAIPVTPADGP 207
Query: 705 LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP 764
+V G +P A +P + + TD P A +V + +P SA +P
Sbjct: 208 VVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIVPVTPADSSFVPVISADSP 267
Query: 765 PLPL----------QDTDLSSAPK-PV--------AAATIVSQQAEEGLTLPQDSAMTPP 805
+P+ TD+ P PV A TI L + +A P
Sbjct: 268 FVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXXXXXSLVVSVTTADDPI 327
Query: 806 LPLQDTD-----LSSAPKPVAAAT-----IVSQQAEEGLTLPQDSAMTPPLPLQDTD--- 852
+P+ D ++ A PV T V +G +P A +P +P+ D
Sbjct: 328 VPVTPADSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPV 387
Query: 853 --LSSAPKPVAAATP-----VSQQAEEGLTLPQDSAMTAPLPLQDTG-----PTSGPEPL 900
++SA P TP VS + +P SA + +P+ T+ +P+
Sbjct: 388 VSVASADSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPI 447
Query: 901 AVATPQTLQAEAGCAPGTE---PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQ 957
TP A+ +P T PV + ++ L P P+ + + P A
Sbjct: 448 VPVTP----ADTPGSPVTSADGPVVPVTSADI--PLVPVTPPDGPVVPVTSADGPVAPVS 501
Query: 958 VQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEAR 1017
P A +P+ AD L P + A + LS E+
Sbjct: 502 SADGPVVPVTPADSPFIPVTTAD--------DLIVPVTPADSPV---LSVTPAESPAIPV 550
Query: 1018 AHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGA-REVPDAPPAACPEVSQ 1076
P +P + + P+ GP + A V PA P +S
Sbjct: 551 TPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVTPADSPVVPVTPADSPVLSV 610
Query: 1077 ARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSA 1136
SPA P V AS DS V + D PA + A
Sbjct: 611 TLADSPAVPVTPADSPVVPVTPADGPVVPVASADS---PFVPVTPADDPIVSVTPAESPA 667
Query: 1137 -PTSQQPEPVLGLGSVEQP---------HEVP-SVLGTPLLQPPENLAKGQPSTPVDRPL 1185
P +Q PV+ + S ++P VP + G P++ G P T D P+
Sbjct: 668 IPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPV 727
Query: 1186 GPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPP--GSLGLPPPQAGVQPAAAA 1243
P SA PP P P D V + P P A V A
Sbjct: 728 VPVTSADSPFV-PVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGP 786
Query: 1244 VSGTTQPLGTGPRVSL----SPHSPLL---SPKVASMDAKDLALQILP 1284
V T GP V + SP P++ SP V A D + + P
Sbjct: 787 VVPVTPADTNGPAVPVTSADSPFVPVIPADSPVVPVTPADDPIVPVTP 834
Score = 72.4 bits (176), Expect = 3e-12
Identities = 164/777 (21%), Positives = 252/777 (32%), Gaps = 93/777 (11%)
Query: 585 IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP 644
+VP + + +P D A P + + D P A +T+V +G +P SV P
Sbjct: 1566 VVPVSPTDGVLVP-DLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVDIP 1624
Query: 645 PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKP 699
+P+ AP +VS +G +P SA P +P+ D ++ A P
Sbjct: 1625 VVPVTPANGPVAPVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSP 1684
Query: 700 VAAAT-----LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT---------- 744
+ T +V + + +P A +P +P+ D S PV +A
Sbjct: 1685 IVPVTPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPVTSADGPVVPVTSAD 1744
Query: 745 --LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM 802
V +G +P SA P P+ D P A + +V + T+P A
Sbjct: 1745 SLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDPTVPVTPAD 1804
Query: 803 TPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 862
+P +P+ + P A + V +GL + S +P+ TD P +A
Sbjct: 1805 SPVVPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVP-DLAD 1863
Query: 863 ATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVA 922
VS + +P A P+ P GP V P PV
Sbjct: 1864 DPVVSVTIADSPVIP---VTPADSPVVLVTPADGP---VVPVTSVDNPVVPVTPADNPVI 1917
Query: 923 TMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADST 982
+ V + + P ++ + + P P A +P ADS
Sbjct: 1918 PVT--PVDDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVTPADSPVIPVASADSP 1975
Query: 983 LGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKP-DSPQKETLEVENQQE 1041
L P + A + + G + P DSP + V +
Sbjct: 1976 L--------VPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSP---VVPVTSADS 2024
Query: 1042 GGLKPLAQEHGPRSALGGAREVPDAPP-------------------AACPEVSQARLLSP 1082
+ A + +P PP CP VS SP
Sbjct: 2025 PVIPVTADSPFVPVTPADSPVIPVTPPDDLVVPVTPIDCPVVPVTLVDCPVVSVTPANSP 2084
Query: 1083 AREERGLSGKSTP-----EPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAP 1137
G P P +P A + + P S+ + S+ D+P P
Sbjct: 2085 VDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSL--IVSVTPA--DSPV---VP 2137
Query: 1138 TSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQ--PSTPVDRPLGP-----DPS 1190
+ PV+ + S + P V V + P A G P TP + P P P
Sbjct: 2138 VTPADSPVISVASADSP--VVPVTPADTVVVPVTPADGPVIPVTPAESPAIPVTPADSPV 2195
Query: 1191 APGTLAGAALPPLEP-PAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQ 1249
P T A + P+ P +P + P D V P + G P A V+
Sbjct: 2196 VPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPG--SPVASADGPVVPVTSADS 2253
Query: 1250 PL-----GTGPRVSLSP-HSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGP 1300
PL G P V ++P SP+ A + L P V P P P P
Sbjct: 2254 PLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSP 2310
Score = 68.6 bits (166), Expect = 5e-11
Identities = 170/795 (21%), Positives = 259/795 (32%), Gaps = 108/795 (13%)
Query: 581 AAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 640
A + ++P +DL +P P +P+ D A + + +G +P
Sbjct: 2041 ADSPVIPVTPPDDLVVPVTPIDCPVVPVTLVDCPVVSVTPANSPVDPVTPADGPVVPVTP 2100
Query: 641 VMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 700
+P +P+ + P A + +VS + +P A +P + + D P
Sbjct: 2101 ADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISVASADSPVVPVTP 2160
Query: 701 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 760
A +V +G +P A +P +P+ D P A +V + +P
Sbjct: 2161 ADTVVVPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPVPP 2220
Query: 761 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 820
A P +P+ D + PVA+A +G +P SA +P +P+ D P
Sbjct: 2221 ASDPVVPVTPADTPGS--PVASA--------DGPVVPVTSADSPLVPVTPGDSPVVPVTP 2270
Query: 821 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAATP-----VSQQA 870
A + + + +G P A P P+ D +S A PV TP V
Sbjct: 2271 ADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTPANIPVVPVPP 2330
Query: 871 EEGLTLPQDSAMTAPLPLQD-----------------TGPTSGPEPLAVATPQTLQAEAG 913
G +P SA + +P+ PT G +A +
Sbjct: 2331 ANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPTDGIPVPDLADDPVVSVTTS 2390
Query: 914 CAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQ-----PAAE 968
+P PV V A P + P VP A V P PA
Sbjct: 2391 DSP-VIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPADSLVVPATP 2449
Query: 969 AGTPWAAQEDAD------STLGMEALSLPE---------PASGAGEEIAEALSRPGREAC 1013
A P + AD +T + +S+ PA G + A ++
Sbjct: 2450 ADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPADGLVVPVTSA------DSV 2503
Query: 1014 LEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGA-REVPDAPPAACP 1072
+ P P + + + + + + P + A V PA P
Sbjct: 2504 VVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFPVTPADSSVVPVTPAGVP 2563
Query: 1073 EVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGC-PDAP 1131
V ++P G P S V S D S V V+ D P +P
Sbjct: 2564 VVP----VTPG------DGPVVPVTPADSLVVPVTSAD----SPVFPVTPADSPVFPVSP 2609
Query: 1132 A-PTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQP--PENLAKGQ--PSTPVDRPLG 1186
A P + PV+ + P + P VL TP P P A G P T D P
Sbjct: 2610 ADDLVVPVTPGDSPVVPV----SPADSPVVLVTPADGPVVPVTPANGPVVPVTSADSPFV 2665
Query: 1187 PDPSAPGTL-----AGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAA 1241
P A G + + P+ P L D +D V PG + P G P
Sbjct: 2666 PVIPADGLVVLDSSTDVLVVPVFPTDGILVPDLADDPVV-PVTPGDDPVVPVTPGDDPVI 2724
Query: 1242 AAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQ 1301
P GP V P +P + P V + A D ++P P P
Sbjct: 2725 PVT-----PADDGPFV---PVTPAVGPVVPDLTADD---SVVPDSLTDDPVISVCP--DD 2771
Query: 1302 GLSAPEQQEDEDSLE 1316
GL P+ D D E
Sbjct: 2772 GLVVPDTVRDSDGPE 2786
Score = 67.8 bits (164), Expect = 8e-11
Identities = 172/864 (19%), Positives = 288/864 (33%), Gaps = 132/864 (15%)
Query: 548 TPQEETSLTLCP-DSPQNLKEEGGLDLPSGRKPVAAATIV-----PRQAKEDLTLPQDSA 601
TP ++ + + P DSP + +P PV T P + + +P SA
Sbjct: 2199 TPADDPVVPVTPADSPI-------VPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSA 2251
Query: 602 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP---QDSVMTPPLPLQDT--ELSSA 656
+P +P+ D P A + + + +G P D + P P D +S A
Sbjct: 2252 DSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPA 2311
Query: 657 PKPVAAAT-----LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAE 711
PV T +V G +P SA +P +P+ D +V
Sbjct: 2312 DSPVVPVTPANIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPT 2371
Query: 712 EGLTLPQ---------DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAM 762
+G+ +P ++ +P +P+ TD P A +V + + +P A
Sbjct: 2372 DGIPVPDLADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPAD 2431
Query: 763 TPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 822
+P +P+ D P A +VS +G +P +A P + + D P A
Sbjct: 2432 SPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPAD 2491
Query: 823 ATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATP-----VSQQAEEGLTLP 877
+V + + + +P A P +P+ D P+ TP VS +++ P
Sbjct: 2492 GLVVPVTSADSVVVPATPADCPLVPVDPAD-----SPIVLFTPYDNPVVSVTSDDSPVFP 2546
Query: 878 QDSAMTAPLPLQDTG-----PTSGPEPLAVATP------QTLQAEAGCAPGTE------P 920
A ++ +P+ G T G P+ TP A++ P T P
Sbjct: 2547 VTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSADSPVFPVTPADSPVFP 2606
Query: 921 VATMAQQEVGEALGPRP----APEEKNAALPTVPEPAALDQVQQDDP-QPAAEAGTPWAA 975
V+ V G P +P + L T + + + P P A +P+
Sbjct: 2607 VSPADDLVVPVTPGDSPVVPVSPADSPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVP 2666
Query: 976 QEDADSTLGMEALS--LPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKE- 1032
AD + +++ + L P + L+ + + D P +P +
Sbjct: 2667 VIPADGLVVLDSSTDVLVVPVFPTDGILVPDLA----DDPVVPVTPGDDPVVPVTPGDDP 2722
Query: 1033 TLEVENQQEGGLKPLAQEHGP--RSALGGAREVPDAPP-----AACPEVSQARLLSPARE 1085
+ V +G P+ GP VPD+ + CP+ L
Sbjct: 2723 VIPVTPADDGPFVPVTPAVGPVVPDLTADDSVVPDSLTDDPVISVCPDDG----LVVPDT 2778
Query: 1086 ERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPT----------- 1134
R G + V T+++ D CP SV L CP P
Sbjct: 2779 VRDSDGPEVSVYPVTGPVVTDSAAD-CPVVSVPLTDGLVVLCPPDEVPAVHDSVTNGLVV 2837
Query: 1135 -----SAPTSQQPE---PVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVD---- 1182
P P P++ + S + P + P++ P + STP D
Sbjct: 2838 PDPVIDGPVFSNPSVDGPIVPVASADNPGVPDPIRAFPVVPKPSTFSPVVTSTPADWIDV 2897
Query: 1183 --RPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEP------------PGSL 1228
P + G +P L P + P +D V P G +
Sbjct: 2898 IVTPADCADVPVNPVNGPVVPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPV 2957
Query: 1229 GLPPPQAGVQPAAAAVSGTTQP--LGTGPRVSLSPH-----SPLLSPKVASMDAKDLALQ 1281
P G+ +G+ P L P V+++P SP + V + D ++
Sbjct: 2958 VTDPATDGLMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVV 3017
Query: 1282 ILPPCQ---VPPP--SGPQSPAGP 1300
P VP P +GP P P
Sbjct: 3018 SNPTTDGLIVPNPLLAGPVVPVTP 3041
Score = 62.8 bits (151), Expect = 2e-09
Identities = 154/712 (21%), Positives = 241/712 (33%), Gaps = 99/712 (13%)
Query: 579 PVAAAT--IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL 636
PV +A ++P + P SA P +P+ D P A + +
Sbjct: 130 PVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFP-------VT 182
Query: 637 PQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 696
P DS P P+ + ++ P A +V G +P A +P + + TD
Sbjct: 183 PADS---PLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVV 239
Query: 697 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL----------QDTDLSSAPKPVAAATLV 746
P A +V + +P SA +P +P+ TD+ P LV
Sbjct: 240 PVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILV 299
Query: 747 SQQAEE---------GLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAAT-----IVS 787
A+E L + +A P +P+ D ++ A PV T V
Sbjct: 300 PAFADETIXXXXXXXSLVVSVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPFVP 359
Query: 788 QQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAAT-----IVSQQAEEGLTLP 837
+G +P A +P +P+ D ++SA P T IVS + +P
Sbjct: 360 AIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPVVP 419
Query: 838 QDSAMTPPLPLQDTD-----LSSAPKPVAAATPVSQ-----QAEEGLTLPQDSAMTAPLP 887
SA +P +P+ D +++A P+ TP + +G +P S A +P
Sbjct: 420 VTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTS---ADIP 476
Query: 888 LQDTGPTSGP-EPLAVA---TPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKN 943
L P GP P+ A A+ P T + + L P +
Sbjct: 477 LVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPVTPADSP 536
Query: 944 AALPTVPEPAALDQVQQDDP-QPAAEAGTPWAAQEDADSTLGMEALSLPE-PASGAGEEI 1001
T E A+ D P P A P ADS +P PA G +
Sbjct: 537 VLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPF------VPVIPADGPVVPV 590
Query: 1002 AEALS-----RPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSA 1056
A S P L A P +P + +G + P+A P
Sbjct: 591 TPADSPVVPVTPADSPVLSVTL-ADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVP 649
Query: 1057 LGGARE-VPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPES 1115
+ A + + PA P + + SP + S P +P T A P +
Sbjct: 650 VTPADDPIVSVTPAESPAIPVTQADSPV-----VPVTSADRPVIP---VTTADGRIVPVT 701
Query: 1116 SVGAVSSLDRGCPDAPAPT-SAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAK 1174
+ G D P PA T +P + PV+ + S + P + P++
Sbjct: 702 AAG-----DPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGP 756
Query: 1175 GQPSTPVDRPLGPDPSAPGTLA--GAALPPLEPPAPCLCQDPQEDSVEDEEP 1224
P + D P+ P SA G +A +A P+ P P P + P
Sbjct: 757 VAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAVPVTSADSP 808
Score = 62.0 bits (149), Expect = 4e-09
Identities = 172/815 (21%), Positives = 269/815 (33%), Gaps = 176/815 (21%)
Query: 549 PQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPL 608
P + + LCP ++P+ V +VP + S P +P+
Sbjct: 2810 PLTDGLVVLCPPD----------EVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPIVPV 2859
Query: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668
D P P+ A +V P+ S +P + + A V
Sbjct: 2860 ASADNPGVPDPIRAFPVV----------PKPSTFSPVVTSTPADWIDVIVTPADCADVPV 2909
Query: 669 QAEEGLTLPQDSAMTPPLPLQDTD-----------LSSAPKPVAAATLVSQQAEEGLTLP 717
G +P S P +P+ TD + PV +V+ A +GL +P
Sbjct: 2910 NPVNGPVVPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVP 2969
Query: 718 QDSAMTPPLPLQ-----DTDLSSA--------------PKPVAAATLVSQQAEEGLTLPQ 758
A P+ D ++ A P P A +++VS +GL +P
Sbjct: 2970 VTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSNPTTDGLIVPN 3029
Query: 759 DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 818
P +P+ TD AP +A V+ +G + + P P +
Sbjct: 3030 PLLAGPVVPVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTTGGPVFPDPTAEGLVVSN 3089
Query: 819 PVAAATIVSQQAEEGL--TLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTL 876
P +V+ + +GL P D A P +P D+ + L
Sbjct: 3090 PTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDVL-------------------VNL 3130
Query: 877 PQDSAM---TAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEAL 933
DS + TA + P P+ L P P PV + +
Sbjct: 3131 VNDSVVPDFTADWTVVSVSP---PDDLVAPDP----------PDEVPVVLVPITD----- 3172
Query: 934 GPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEP 993
GP P+ L PA V P P ADS + +P+P
Sbjct: 3173 GP-VVPDLTTDGLVVSVTPAGAPVV------PVFLTDCPDVTVTPADSPV------VPDP 3219
Query: 994 ASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGP 1053
+S G +A++L G L D PDSP + + +G + P GP
Sbjct: 3220 SSD-GPVVADSLDDDG----LVPVTPADDSVVPDSPANGLVVPDPTTDGPVAPDPSVDGP 3274
Query: 1054 RSALGGAREVPDAPP-----AACPEVSQARL--LSPAREERG---LSGKSTPEPTLPSAV 1103
+ A DAP A CP+V+ L + +RG ++G ST +P + +
Sbjct: 3275 VVPVTPA----DAPTVSVTLADCPDVTVTPPDGLVVSDSKRGGPVVTGLSTNDPVITATP 3330
Query: 1104 ATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ---------PEPVLGLGSVEQP 1154
A + + P + V CPD P +P P L +E P
Sbjct: 3331 ADFSDVTVTP-ADFEDVPVTPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDDLVVLEPP 3389
Query: 1155 HEVPSVLGTPLLQPPENLAKG-QPSTPV-DRPLGPDPSAPGTL--AGAALPPLEPPAPCL 1210
+VP V P+ ++ G S P+ + DPS G++ A P+ P
Sbjct: 3390 DKVPVV--------PDPISNGLVVSDPITNNTAATDPSVDGSVVPVSPADGPVAPVTLAD 3441
Query: 1211 CQD----PQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHS-PL 1265
C D P +DSV + A + P V ++P S P+
Sbjct: 3442 CPDVTITPADDSVVSD---------------SKIRAEFEDVPVTIADCPNVPVNPKSGPV 3486
Query: 1266 LSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGP 1300
+S DLA+ P +PPP +P P
Sbjct: 3487 VS---------DLAVD-CPVVPIPPPDDLVAPEPP 3511
Score = 60.8 bits (146), Expect = 9e-09
Identities = 193/917 (21%), Positives = 306/917 (33%), Gaps = 112/917 (12%)
Query: 438 DGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTA----TVTPHTLQVAPG 493
DGTV P D A S ++S T +GL + A VTP +AP
Sbjct: 2994 DGTVVSPTIGGPVVPDPSADSS----VVSNPTTDGLIVPNPLLAGPVVPVTPTDGPLAPV 3049
Query: 494 LQVEVA-TRVTPQAGEEETDSTAGQESAAMAMPQPSQEGI--------SEILGQESVTAE 544
+ + VTP G T G P P+ EG+ ++ S
Sbjct: 3050 ILADCPDVTVTPADGPVVCAFTTG----GPVFPDPTAEGLVVSNPTVDDPVVTNPSTKGL 3105
Query: 545 KLPTPQEETSLTL----CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
TP + + + CPD NL + + A T+V +DL P
Sbjct: 3106 VSATPADCADVPVIPADCPDVLVNLVNDSVVP-----DFTADWTVVSVSPPDDLVAPDPP 3160
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
P + + TD P +VS +P P + + + P P
Sbjct: 3161 DEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVVPVFLTDCPDVTVTPADSPVVPDPS 3220
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
+ +V+ + D + P P D+ + +P A +V +G P S
Sbjct: 3221 SDGPVVADSLD-------DDGLVPVTPADDSVVPDSP---ANGLVVPDPTTDGPVAPDPS 3270
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP---PLPLQDTDLSSAP 777
P +P+ D + +A V+ +GL + P L D +++ P
Sbjct: 3271 VDGPVVPVTPADAPTVSVTLADCPDVTVTPPDGLVVSDSKRGGPVVTGLSTNDPVITATP 3330
Query: 778 KPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL- 836
+ T+ E+ +P A P +P+ + V + +++ + L
Sbjct: 3331 ADFSDVTVTPADFED---VPVTPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDDLVVLE 3387
Query: 837 PQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSA--MTAPLPLQD-TGP 893
P D P P+ + + S P+ T + + +G +P A AP+ L D
Sbjct: 3388 PPDKVPVVPDPISNGLVVS--DPITNNTAATDPSVDGSVVPVSPADGPVAPVTLADCPDV 3445
Query: 894 TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPA 953
T P +V + ++AE P T +A V G P + P VP P
Sbjct: 3446 TITPADDSVVSDSKIRAEFEDVPVT--IADCPNVPVNPKSG--PVVSDLAVDCPVVPIPP 3501
Query: 954 ALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAG-EEIAEALSRPGREA 1012
D V P+P E P DS + + ++ AS + I + P
Sbjct: 3502 PDDLVA---PEPPDE--VPVVPDPITDSLVVSDPMTDGPVASDPSIDGIVVPVVSPSGLL 3556
Query: 1013 CLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACP 1072
L++ A PD+ + +G + VPD+ P CP
Sbjct: 3557 VLDSVADV--SILPDTSADVPVTPVTLADGSV------------------VPDSAP-DCP 3595
Query: 1073 EVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPA 1132
V + + G P P V + + D S+ + PD P
Sbjct: 3596 VVPVLPTDGFVVLDLLVDGVVVPNPADVGPVVPDPTTDG--PDSIKDFPLVPDPWPDCPV 3653
Query: 1133 PTSAPTSQQPEPVLGLGSVEQPHEVPSVLG---TPLLQPPENLAKGQPSTPVDRPLGPDP 1189
P ++ PV+ L S VP G L+ P +NL P D P+ PDP
Sbjct: 3654 ---VPVTRTDGPVV-LDSSADGVVVPVTPGDDSVALVTPTDNLV--VPDLTTDGPVVPDP 3707
Query: 1190 SAPG-----TLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAV 1244
SA G +LA L P P + + D+ +P L P +P+A +
Sbjct: 3708 SADGPVVLVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVTDCPLVP-----EPSANGL 3762
Query: 1245 SGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPA-GPQGL 1303
T L GP V P P V + + L ++P P P +P G
Sbjct: 3763 V-VTDSLDEGPVV---PDPSADDPVVLNPETNGL---VVPDISANGPVVPDTPTDGSDAT 3815
Query: 1304 SAPEQQEDEDSLEEDSP 1320
P+ + D P
Sbjct: 3816 VTPDDCSEVFVTATDGP 3832
Score = 60.1 bits (144), Expect = 2e-08
Identities = 99/432 (22%), Positives = 150/432 (34%), Gaps = 50/432 (11%)
Query: 541 VTAEKLPTPQEETSLTL--CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQ 598
V+ K+ E+ +T+ CP+ P N K P +VP +DL P+
Sbjct: 3455 VSDSKIRAEFEDVPVTIADCPNVPVNPKSG-----PVVSDLAVDCPVVPIPPPDDLVAPE 3509
Query: 599 DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP---------QDSVMTPPLPLQ 649
P +P TD P+ + S + +G+ +P DSV + L
Sbjct: 3510 PPDEVPVVPDPITDSLVVSDPMTDGPVASDPSIDGIVVPVVSPSGLLVLDSVADVSI-LP 3568
Query: 650 DTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQ 709
DT SA PV TL +G +P + P +P+ TD + +V
Sbjct: 3569 DT---SADVPVTPVTLA-----DGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVVPNP 3620
Query: 710 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 769
A+ G +P D P ++D L P P +V +G + SA +P+
Sbjct: 3621 ADVGPVVP-DPTTDGPDSIKDFPL--VPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPVT 3677
Query: 770 DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 829
D S A +V +G +P SA P + + D P P T+V
Sbjct: 3678 PGDDSVALVTPTDNLVVPDLTTDGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTVV--- 3734
Query: 830 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQ 889
P A P TD P+P A V+ +EG +P SA
Sbjct: 3735 -------PNSVADNPVALDPVTDCPLVPEPSANGLVVTDSLDEGPVVPDPSA-------- 3779
Query: 890 DTGPTSGPEPLAVATPQTLQAEAGCAPGTE---PVATMAQQEVGEALGPRPAPEEKNAAL 946
D PE + P + A P T AT+ + E + +
Sbjct: 3780 DDPVVLNPETNGLVVPD-ISANGPVVPDTPTDGSDATVTPDDCSEVFVTATDGPDVVSDC 3838
Query: 947 PTVPEPAALDQV 958
P VPE + D +
Sbjct: 3839 PIVPETSDDDLI 3850
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 80.9 bits (198), Expect = 9e-15
Identities = 197/972 (20%), Positives = 339/972 (34%), Gaps = 144/972 (14%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 ----------GLDLP------------SGRKPVAAA-----TIVPRQAKEDLTLPQDSAM 602
G +P SG+ P +A T + + +E+ ++P A
Sbjct: 126 KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 603 TPPLPLQDTDLSSAPKPVAAAT----IVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPK 658
P + S+ + ++++ + + + + + SV T P + +AP
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR----KAAPA 241
Query: 659 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQ 718
P V+ Q + G P A P + ++ S + A A SQ L
Sbjct: 242 PGKVGD-VTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778
+A P + AP A A V+ Q + G P++ + + + S + +
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGA--VASQTKAGK--PEEDSES-----SSEESSDSEE 351
Query: 779 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATIVSQQAEEGL 834
AA + Q G T +A P + AP P A ++ E+
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
Query: 835 TLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPT 894
+ ++S P Q AP+ AA+ P + +G AP P + TGP
Sbjct: 412 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAPAPPRKTGPA 462
Query: 895 -------------------SGPEPLAVATPQTLQAEA-GCAPGTEPVATMAQQEVGEALG 934
S + A+A Q + G +P +P +TM +G+ G
Sbjct: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Query: 935 PRPAPEEKNAALPT--VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLG--MEALSL 990
P P P + A P+ V + + ++ +++ P A + +LG ++A
Sbjct: 523 PVP-PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT 581
Query: 991 PEPASGAGEEIAEALSRPGREACL---EARAHTGDGAKPDSPQKETLEVENQQEGGLKPL 1047
PA G ++ + E + E+ + D A DS + Q + LK
Sbjct: 582 SSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIP 639
Query: 1048 AQEHGPR--SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVAT 1105
+ P+ + A+ P P + SPA ++G T P S+ +
Sbjct: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAG-GTQRPAEDSSSSE 697
Query: 1106 EASLDSCPESS-----VGAVSSLDRGCP--DAPAPTSAPTSQQPEPVL------------ 1146
E+ DS E + VG S+ +G A P Q PVL
Sbjct: 698 ES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK 755
Query: 1147 -----GLGSVEQPHEVPSVLGTPL---LQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGA 1198
S E+ + +P + AK P+ SAPG + A
Sbjct: 756 AEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTA 815
Query: 1199 ALPP-------LEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPL 1251
A ++PP ++PQ +V P +P V AA A +G +
Sbjct: 816 AAQAKQRSPSKVKPPV----RNPQNSTVLARGPAS---VPSVGKAVATAAQAQTGPEEDS 868
Query: 1252 GTGPRVSLSPH-SPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQE 1310
G+ S S + L+ S + + P + P +P G G SA + +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Query: 1311 DEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQ 1370
+DS S + SDS GE+ A + ++ P + G T A+A+
Sbjct: 929 QDDSGS--------SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQA 980
Query: 1371 SRSEKKARKAMS 1382
+ + +KAR + S
Sbjct: 981 ASTPRKARASES 992
Score = 77.8 bits (190), Expect = 7e-14
Identities = 242/1186 (20%), Positives = 408/1186 (34%), Gaps = 167/1186 (14%)
Query: 348 LAGEGEEDSTSASFLQSLSDLSITEGMDEAF---AFRDDTSAASSDSDSASYAEADDERL 404
L+G+ S S +L + EG AF A SA +DS S + + DE
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 405 YSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQEL 464
G+P + ++ S T+E A + G V+ V+ + A ++ E
Sbjct: 212 VEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA---KKPEE 268
Query: 465 ISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT---RVTPQAGEEETDSTAGQESAA 521
SE +EEG +E+ A LQV A+ + TP G+ T + G+ A
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP--GKGATPAPPGKAGAV 326
Query: 522 MAM-----PQPSQEGISEILGQESVTAEKLPTPQE--------ETSLTLCPDSP-QNLKE 567
+ P+ E SE + S + E+ P + +TS +P +
Sbjct: 327 ASQTKAGKPEEDSESSSE---ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR 383
Query: 568 EGGLDLPSGRK-PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 626
+G P G+ P A ++ ++ + ++S P Q AP+ AA+
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA 443
Query: 627 SQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDS-----A 681
+ +G P P + T P AA V +Q E+ + ++S A
Sbjct: 444 KESPRKG---------AAPAPPRKT------GPAAAQVQVGKQEEDSRSSSEESDSDREA 488
Query: 682 MTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL-------QDTDLS 734
+ Q L +P+ A+T+ +G + P P +D++ S
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 735 ------SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788
S+ V A +Q+ G L +P + P A V
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP---------AKGPPQKAGPVAVQV 599
Query: 789 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL 848
+AE+ P D++ + D AP + AA QA+ L +PQ A
Sbjct: 600 KAEK----PMDNSESSEESSDSADSEEAPAAMTAA-----QAKPALKIPQTKACPKK--- 647
Query: 849 QDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA---PLPLQDTGPTSGPEPLAVATP 905
+T S+ PV T ++A + S A P +D+ + + T
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707
Query: 906 QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQP 965
+ + G A V +LG AP PTV + A + Q+D
Sbjct: 708 LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA--EKQEDSESS 765
Query: 966 AAEAGTPWAAQEDAD-STLGMEALSLPEPASGAGEEIAEALSRPGR--EACLEARAHTGD 1022
E+ + AA A T + + PA+ +S PG+ A +A+ +
Sbjct: 766 EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
Query: 1023 GAKPD--SPQKETL------EVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA---- 1070
KP +PQ T+ V + + + GP G + E D+ A
Sbjct: 826 KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLA 885
Query: 1071 ----CPEVSQAR-LLSPAREE-RGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLD 1124
+ Q R L+PA+E R + + P T PSA DS SS +
Sbjct: 886 QVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS--------GSSSE 937
Query: 1125 RGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRP 1184
D AP + ++Q +P L P+ P+ P A+ Q ++ +
Sbjct: 938 ESDSDGEAPAAVTSAQVIKPPL---IFVDPNRSPA-------GPAATPAQAQAASTPRKA 987
Query: 1185 LGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPA--AA 1242
+ +A + + + + P CL + + V + AG + ++
Sbjct: 988 RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS 1047
Query: 1243 AVSGTTQPLGTGPRVSLSPHS-PLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQ 1301
+S + G +V + + P SP+ S+ AK P+ P Q
Sbjct: 1048 RISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKG----------TNKLRKPKLPEVQQ 1097
Query: 1302 GLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGS 1361
APE +D + + S SG D G A+ + P
Sbjct: 1098 ATKAPESSDDSEDSSDSS-----SGSEEDGEGPQGAKSAHTLV-----------GPTPSR 1141
Query: 1362 EETIAK--AKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASD 1419
ET+ + A +S + + S L G+T Q SK A P + SP+
Sbjct: 1142 TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK------ATPKLDSSPSVS 1195
Query: 1420 TYVVF---GEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPR 1462
+ + + K E QQ + K S P+ + +P+
Sbjct: 1196 STLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1241
Score = 66.2 bits (160), Expect = 2e-10
Identities = 155/802 (19%), Positives = 276/802 (34%), Gaps = 91/802 (11%)
Query: 729 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788
+D L + V+ S+ +EE ++A P L+S V A + S
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPR------LASTNSSVLGADLPSS 120
Query: 789 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL 848
E+ + + T +S P P T+ + + + + + L
Sbjct: 121 MKEKAKAETEKAGKTG---------NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVS 171
Query: 849 QDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTL 908
+ + S P AAA P A + + +D++ ++ + P+ P + ++ T
Sbjct: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
Query: 909 QAEAG-CAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAA 967
++ A AP V + Q G AL P ++ PE + + + + A
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK--------PEEESESSEEGSESEEEA 283
Query: 968 EAGTPWAAQEDADSTLGMEALSLPEPAS-GAGEEIAEALSRPGREACLEARAHTGDGAKP 1026
AGT + + ++ L + A S P + G G A PG+ + ++ G +
Sbjct: 284 PAGTR-SQVKASEKILQVRAASAPAKGTPGKGATPAP----PGKAGAVASQTKAGKPEED 338
Query: 1027 DSPQKETLEVENQQEGGLKPL--AQEHGPRSALGGA----REVP-----DAPPAAC-PEV 1074
E ++ K L A+ G S +G A +E P APP P V
Sbjct: 339 SESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 398
Query: 1075 SQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPT 1134
++A+ + + S +S E P+ +S A S +G AP
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRK 458
Query: 1135 SAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGT 1194
+ P + Q + +G E+ S + A + +PLG P
Sbjct: 459 TGPAAAQVQ----VGKQEEDSRSSSEESDS-----DREALAAMNAAQVKPLGKSPQVK-- 507
Query: 1195 LAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTG 1254
PA + P G+ +PP + G +A V + +
Sbjct: 508 -----------PASTMGMGPLGK--------GAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 1255 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDS 1314
S + VA K L + P GP AGP + ++ ++S
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
Query: 1315 LEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSE 1374
E S + S ++ +A + + PQT CP + S + +++
Sbjct: 609 --ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 666
Query: 1375 KKARKAMSKLGLRQ-IQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLS 1433
+KA A S G + G T+ + S + ++ + + V G+AK
Sbjct: 667 RKAGTATSPAGSSPAVAGGTQRPAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKG 721
Query: 1434 QQVHKAAAEKFK----------VPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1483
QV KAA+ K +P + V + + E EEE + EE
Sbjct: 722 LQV-KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 1484 ELRDIELVMAQANVSRAKAVRA 1505
++ A+AN + A+A A
Sbjct: 781 VKTSVKKTQAKANPAAARAPSA 802
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 80.9 bits (198), Expect = 9e-15
Identities = 197/972 (20%), Positives = 339/972 (34%), Gaps = 144/972 (14%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 ----------GLDLP------------SGRKPVAAA-----TIVPRQAKEDLTLPQDSAM 602
G +P SG+ P +A T + + +E+ ++P A
Sbjct: 126 KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 603 TPPLPLQDTDLSSAPKPVAAAT----IVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPK 658
P + S+ + ++++ + + + + + SV T P + +AP
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR----KAAPA 241
Query: 659 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQ 718
P V+ Q + G P A P + ++ S + A A SQ L
Sbjct: 242 PGKVGD-VTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778
+A P + AP A A V+ Q + G P++ + + + S + +
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGA--VASQTKAGK--PEEDSES-----SSEESSDSEE 351
Query: 779 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATIVSQQAEEGL 834
AA + Q G T +A P + AP P A ++ E+
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
Query: 835 TLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPT 894
+ ++S P Q AP+ AA+ P + +G AP P + TGP
Sbjct: 412 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAPAPPRKTGPA 462
Query: 895 -------------------SGPEPLAVATPQTLQAEA-GCAPGTEPVATMAQQEVGEALG 934
S + A+A Q + G +P +P +TM +G+ G
Sbjct: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Query: 935 PRPAPEEKNAALPT--VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLG--MEALSL 990
P P P + A P+ V + + ++ +++ P A + +LG ++A
Sbjct: 523 PVP-PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT 581
Query: 991 PEPASGAGEEIAEALSRPGREACL---EARAHTGDGAKPDSPQKETLEVENQQEGGLKPL 1047
PA G ++ + E + E+ + D A DS + Q + LK
Sbjct: 582 SSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIP 639
Query: 1048 AQEHGPR--SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVAT 1105
+ P+ + A+ P P + SPA ++G T P S+ +
Sbjct: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAG-GTQRPAEDSSSSE 697
Query: 1106 EASLDSCPESS-----VGAVSSLDRGCP--DAPAPTSAPTSQQPEPVL------------ 1146
E+ DS E + VG S+ +G A P Q PVL
Sbjct: 698 ES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK 755
Query: 1147 -----GLGSVEQPHEVPSVLGTPL---LQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGA 1198
S E+ + +P + AK P+ SAPG + A
Sbjct: 756 AEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTA 815
Query: 1199 ALPP-------LEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPL 1251
A ++PP ++PQ +V P +P V AA A +G +
Sbjct: 816 AAQAKQRSPSKVKPPV----RNPQNSTVLARGPAS---VPSVGKAVATAAQAQTGPEEDS 868
Query: 1252 GTGPRVSLSPH-SPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQE 1310
G+ S S + L+ S + + P + P +P G G SA + +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Query: 1311 DEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQ 1370
+DS S + SDS GE+ A + ++ P + G T A+A+
Sbjct: 929 QDDSGS--------SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQA 980
Query: 1371 SRSEKKARKAMS 1382
+ + +KAR + S
Sbjct: 981 ASTPRKARASES 992
Score = 80.1 bits (196), Expect = 2e-14
Identities = 247/1204 (20%), Positives = 419/1204 (34%), Gaps = 166/1204 (13%)
Query: 348 LAGEGEEDSTSASFLQSLSDLSITEGMDEAF---AFRDDTSAASSDSDSASYAEADDERL 404
L+G+ S S +L + EG AF A SA +DS S + + DE
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 405 YSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQEL 464
G+P + ++ S T+E A + G V+ V+ + A ++ E
Sbjct: 212 VEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA---KKPEE 268
Query: 465 ISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT---RVTPQAGEEETDSTAGQESAA 521
SE +EEG +E+ A LQV A+ + TP G+ T + G+ A
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP--GKGATPAPPGKAGAV 326
Query: 522 MAM-----PQPSQEGISEILGQESVTAEKLPTPQE--------ETSLTLCPDSP-QNLKE 567
+ P+ E SE + S + E+ P + +TS +P +
Sbjct: 327 ASQTKAGKPEEDSESSSE---ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR 383
Query: 568 EGGLDLPSGRK-PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 626
+G P G+ P A ++ ++ + ++S P Q AP+ AA+
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA 443
Query: 627 SQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDS-----A 681
+ +G P P + T P AA V +Q E+ + ++S A
Sbjct: 444 KESPRKG---------AAPAPPRKT------GPAAAQVQVGKQEEDSRSSSEESDSDREA 488
Query: 682 MTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL-------QDTDLS 734
+ Q L +P+ A+T+ +G + P P +D++ S
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 735 ------SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788
S+ V A +Q+ G L +P + P A V
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP---------AKGPPQKAGPVAVQV 599
Query: 789 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL 848
+AE+ P D++ + D AP + AA QA+ L +PQ A
Sbjct: 600 KAEK----PMDNSESSEESSDSADSEEAPAAMTAA-----QAKPALKIPQTKACPKK--- 647
Query: 849 QDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA---PLPLQDTGPTSGPEPLAVATP 905
+T S+ PV T ++A + S A P +D+ + + T
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707
Query: 906 QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQP 965
+ + G A V +LG AP PTV + A + Q+D
Sbjct: 708 LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA--EKQEDSESS 765
Query: 966 AAEAGTPWAAQEDAD-STLGMEALSLPEPASGAGEEIAEALSRPGR--EACLEARAHTGD 1022
E+ + AA A T + + PA+ +S PG+ A +A+ +
Sbjct: 766 EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
Query: 1023 GAKPD--SPQKETL------EVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA---- 1070
KP +PQ T+ V + + + GP G + E D+ A
Sbjct: 826 KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLA 885
Query: 1071 ----CPEVSQAR-LLSPAREE-RGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLD 1124
+ Q R L+PA+E R + + P T PSA DS SS +
Sbjct: 886 QVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS--------GSSSE 937
Query: 1125 RGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRP 1184
D AP + ++Q +P L P+ P+ P A+ Q ++ +
Sbjct: 938 ESDSDGEAPAAVTSAQVIKPPL---IFVDPNRSPA-------GPAATPAQAQAASTPRKA 987
Query: 1185 LGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAV 1244
+ +A + + + + P CL + + V + AG + +
Sbjct: 988 RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS 1047
Query: 1245 SGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQIL---------PPCQVPPPSGPQ 1295
+ GP +S +P AS+ AL++L P + P SG
Sbjct: 1048 RISDGKKQEGPATQVSKKNP------ASLPLTQAALKVLAQKASEAQPPVARTQPSSGVD 1101
Query: 1296 SPAGPQGLSAPE----QQEDEDSLE-------EDSPRALGSGQHSDSHGESSAELDEQDI 1344
S G ++P+ Q + + L + + +A S S+ +SS+ E+D
Sbjct: 1102 SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG-SEEDG 1160
Query: 1345 LAPQTVQ-CPAQAPAGGSEETIAK--AKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSK 1401
PQ + P ET+ + A +S + + S L G+T Q SK
Sbjct: 1161 EGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1220
Query: 1402 NILFVIAKPDVFKSPASDTYVVF---GEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESA 1458
A P + SP+ + + + K E QQ + K S P+ +
Sbjct: 1221 ------ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1274
Query: 1459 PRPR 1462
+P+
Sbjct: 1275 RKPK 1278
Score = 66.2 bits (160), Expect = 2e-10
Identities = 155/802 (19%), Positives = 276/802 (34%), Gaps = 91/802 (11%)
Query: 729 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788
+D L + V+ S+ +EE ++A P L+S V A + S
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPR------LASTNSSVLGADLPSS 120
Query: 789 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL 848
E+ + + T +S P P T+ + + + + + L
Sbjct: 121 MKEKAKAETEKAGKTG---------NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVS 171
Query: 849 QDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTL 908
+ + S P AAA P A + + +D++ ++ + P+ P + ++ T
Sbjct: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
Query: 909 QAEAG-CAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAA 967
++ A AP V + Q G AL P ++ PE + + + + A
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK--------PEEESESSEEGSESEEEA 283
Query: 968 EAGTPWAAQEDADSTLGMEALSLPEPAS-GAGEEIAEALSRPGREACLEARAHTGDGAKP 1026
AGT + + ++ L + A S P + G G A PG+ + ++ G +
Sbjct: 284 PAGTR-SQVKASEKILQVRAASAPAKGTPGKGATPAP----PGKAGAVASQTKAGKPEED 338
Query: 1027 DSPQKETLEVENQQEGGLKPL--AQEHGPRSALGGA----REVP-----DAPPAAC-PEV 1074
E ++ K L A+ G S +G A +E P APP P V
Sbjct: 339 SESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 398
Query: 1075 SQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPT 1134
++A+ + + S +S E P+ +S A S +G AP
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRK 458
Query: 1135 SAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGT 1194
+ P + Q + +G E+ S + A + +PLG P
Sbjct: 459 TGPAAAQVQ----VGKQEEDSRSSSEESDS-----DREALAAMNAAQVKPLGKSPQVK-- 507
Query: 1195 LAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTG 1254
PA + P G+ +PP + G +A V + +
Sbjct: 508 -----------PASTMGMGPLGK--------GAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 1255 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDS 1314
S + VA K L + P GP AGP + ++ ++S
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
Query: 1315 LEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSE 1374
E S + S ++ +A + + PQT CP + S + +++
Sbjct: 609 --ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 666
Query: 1375 KKARKAMSKLGLRQ-IQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLS 1433
+KA A S G + G T+ + S + ++ + + V G+AK
Sbjct: 667 RKAGTATSPAGSSPAVAGGTQRPAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKG 721
Query: 1434 QQVHKAAAEKFK----------VPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1483
QV KAA+ K +P + V + + E EEE + EE
Sbjct: 722 LQV-KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 1484 ELRDIELVMAQANVSRAKAVRA 1505
++ A+AN + A+A A
Sbjct: 781 VKTSVKKTQAKANPAAARAPSA 802
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 80.9 bits (198), Expect = 9e-15
Identities = 197/972 (20%), Positives = 339/972 (34%), Gaps = 144/972 (14%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 ----------GLDLP------------SGRKPVAAA-----TIVPRQAKEDLTLPQDSAM 602
G +P SG+ P +A T + + +E+ ++P A
Sbjct: 126 KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 603 TPPLPLQDTDLSSAPKPVAAAT----IVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPK 658
P + S+ + ++++ + + + + + SV T P + +AP
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR----KAAPA 241
Query: 659 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQ 718
P V+ Q + G P A P + ++ S + A A SQ L
Sbjct: 242 PGKVGD-VTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778
+A P + AP A A V+ Q + G P++ + + + S + +
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGA--VASQTKAGK--PEEDSES-----SSEESSDSEE 351
Query: 779 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATIVSQQAEEGL 834
AA + Q G T +A P + AP P A ++ E+
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
Query: 835 TLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPT 894
+ ++S P Q AP+ AA+ P + +G AP P + TGP
Sbjct: 412 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAPAPPRKTGPA 462
Query: 895 -------------------SGPEPLAVATPQTLQAEA-GCAPGTEPVATMAQQEVGEALG 934
S + A+A Q + G +P +P +TM +G+ G
Sbjct: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Query: 935 PRPAPEEKNAALPT--VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLG--MEALSL 990
P P P + A P+ V + + ++ +++ P A + +LG ++A
Sbjct: 523 PVP-PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT 581
Query: 991 PEPASGAGEEIAEALSRPGREACL---EARAHTGDGAKPDSPQKETLEVENQQEGGLKPL 1047
PA G ++ + E + E+ + D A DS + Q + LK
Sbjct: 582 SSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIP 639
Query: 1048 AQEHGPR--SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVAT 1105
+ P+ + A+ P P + SPA ++G T P S+ +
Sbjct: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAG-GTQRPAEDSSSSE 697
Query: 1106 EASLDSCPESS-----VGAVSSLDRGCP--DAPAPTSAPTSQQPEPVL------------ 1146
E+ DS E + VG S+ +G A P Q PVL
Sbjct: 698 ES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK 755
Query: 1147 -----GLGSVEQPHEVPSVLGTPL---LQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGA 1198
S E+ + +P + AK P+ SAPG + A
Sbjct: 756 AEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTA 815
Query: 1199 ALPP-------LEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPL 1251
A ++PP ++PQ +V P +P V AA A +G +
Sbjct: 816 AAQAKQRSPSKVKPPV----RNPQNSTVLARGPAS---VPSVGKAVATAAQAQTGPEEDS 868
Query: 1252 GTGPRVSLSPH-SPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQE 1310
G+ S S + L+ S + + P + P +P G G SA + +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Query: 1311 DEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQ 1370
+DS S + SDS GE+ A + ++ P + G T A+A+
Sbjct: 929 QDDSGS--------SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQA 980
Query: 1371 SRSEKKARKAMS 1382
+ + +KAR + S
Sbjct: 981 ASTPRKARASES 992
Score = 78.2 bits (191), Expect = 6e-14
Identities = 242/1186 (20%), Positives = 407/1186 (34%), Gaps = 168/1186 (14%)
Query: 348 LAGEGEEDSTSASFLQSLSDLSITEGMDEAF---AFRDDTSAASSDSDSASYAEADDERL 404
L+G+ S S +L + EG AF A SA +DS S + + DE
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 405 YSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQEL 464
G+P + ++ S T+E A + G V+ V+ + A ++ E
Sbjct: 212 VEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA---KKPEE 268
Query: 465 ISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT---RVTPQAGEEETDSTAGQESAA 521
SE +EEG +E+ A LQV A+ + TP G+ T + G+ A
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP--GKGATPAPPGKAGAV 326
Query: 522 MAM-----PQPSQEGISEILGQESVTAEKLPTPQE--------ETSLTLCPDSP-QNLKE 567
+ P+ E SE + S + E+ P + +TS +P +
Sbjct: 327 ASQTKAGKPEEDSESSSE---ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR 383
Query: 568 EGGLDLPSGRK-PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 626
+G P G+ P A ++ ++ + ++S P Q AP+ AA+
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA 443
Query: 627 SQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDS-----A 681
+ +G P P + T P AA V +Q E+ + ++S A
Sbjct: 444 KESPRKG---------AAPAPPRKT------GPAAAQVQVGKQEEDSRSSSEESDSDREA 488
Query: 682 MTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL-------QDTDLS 734
+ Q L +P+ A+T+ +G + P P +D++ S
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 735 ------SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788
S+ V A +Q+ G L +P + P A V
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP---------AKGPPQKAGPVAVQV 599
Query: 789 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL 848
+AE+ P D++ + D AP + AA QA+ L +PQ A
Sbjct: 600 KAEK----PMDNSESSEESSDSADSEEAPAAMTAA-----QAKPALKIPQTKACPKK--- 647
Query: 849 QDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA---PLPLQDTGPTSGPEPLAVATP 905
+T S+ PV T ++A + S A P +D+ + + T
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707
Query: 906 QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQP 965
+ + G A V +LG AP PTV + A + Q+D
Sbjct: 708 LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA--EKQEDSESS 765
Query: 966 AAEAGTPWAAQEDAD-STLGMEALSLPEPASGAGEEIAEALSRPGR--EACLEARAHTGD 1022
E+ + AA A T + + PA+ +S PG+ A +A+ +
Sbjct: 766 EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
Query: 1023 GAKPD--SPQKETL------EVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA---- 1070
KP +PQ T+ V + + + GP G + E D+ A
Sbjct: 826 KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLA 885
Query: 1071 ----CPEVSQAR-LLSPAREE-RGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLD 1124
+ Q R L+PA+E R + + P T PSA DS SS +
Sbjct: 886 QVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS--------GSSSE 937
Query: 1125 RGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRP 1184
D AP + ++Q +P L P+ P+ P A+ Q ++ +
Sbjct: 938 ESDSDGEAPAAVTSAQVIKPPL---IFVDPNRSPA-------GPAATPAQAQAASTPRKA 987
Query: 1185 LGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPA--AA 1242
+ +A + + + + P CL + + V + AG + ++
Sbjct: 988 RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS 1047
Query: 1243 AVSGTTQPLGTGPRVSLSPHS-PLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQ 1301
+S + G +V + + P SP+ S+ AK P+ P Q
Sbjct: 1048 RISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKG----------TNKLRKPKLPEVQQ 1097
Query: 1302 GLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGS 1361
APE +D + + S SG D G A+ P
Sbjct: 1098 ATKAPESSDDSEDSSDSS-----SGSEEDGEGPQGAK------------SAHTLGPTPSR 1140
Query: 1362 EETIAK--AKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASD 1419
ET+ + A +S + + S L G+T Q SK A P + SP+
Sbjct: 1141 TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK------ATPKLDSSPSVS 1194
Query: 1420 TYVVF---GEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPR 1462
+ + + K E QQ + K S P+ + +P+
Sbjct: 1195 STLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1240
Score = 66.2 bits (160), Expect = 2e-10
Identities = 155/802 (19%), Positives = 276/802 (34%), Gaps = 91/802 (11%)
Query: 729 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788
+D L + V+ S+ +EE ++A P L+S V A + S
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPR------LASTNSSVLGADLPSS 120
Query: 789 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL 848
E+ + + T +S P P T+ + + + + + L
Sbjct: 121 MKEKAKAETEKAGKTG---------NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVS 171
Query: 849 QDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTL 908
+ + S P AAA P A + + +D++ ++ + P+ P + ++ T
Sbjct: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
Query: 909 QAEAG-CAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAA 967
++ A AP V + Q G AL P ++ PE + + + + A
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK--------PEEESESSEEGSESEEEA 283
Query: 968 EAGTPWAAQEDADSTLGMEALSLPEPAS-GAGEEIAEALSRPGREACLEARAHTGDGAKP 1026
AGT + + ++ L + A S P + G G A PG+ + ++ G +
Sbjct: 284 PAGTR-SQVKASEKILQVRAASAPAKGTPGKGATPAP----PGKAGAVASQTKAGKPEED 338
Query: 1027 DSPQKETLEVENQQEGGLKPL--AQEHGPRSALGGA----REVP-----DAPPAAC-PEV 1074
E ++ K L A+ G S +G A +E P APP P V
Sbjct: 339 SESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 398
Query: 1075 SQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPT 1134
++A+ + + S +S E P+ +S A S +G AP
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRK 458
Query: 1135 SAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGT 1194
+ P + Q + +G E+ S + A + +PLG P
Sbjct: 459 TGPAAAQVQ----VGKQEEDSRSSSEESDS-----DREALAAMNAAQVKPLGKSPQVK-- 507
Query: 1195 LAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTG 1254
PA + P G+ +PP + G +A V + +
Sbjct: 508 -----------PASTMGMGPLGK--------GAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 1255 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDS 1314
S + VA K L + P GP AGP + ++ ++S
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
Query: 1315 LEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSE 1374
E S + S ++ +A + + PQT CP + S + +++
Sbjct: 609 --ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 666
Query: 1375 KKARKAMSKLGLRQ-IQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLS 1433
+KA A S G + G T+ + S + ++ + + V G+AK
Sbjct: 667 RKAGTATSPAGSSPAVAGGTQRPAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKG 721
Query: 1434 QQVHKAAAEKFK----------VPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1483
QV KAA+ K +P + V + + E EEE + EE
Sbjct: 722 LQV-KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 1484 ELRDIELVMAQANVSRAKAVRA 1505
++ A+AN + A+A A
Sbjct: 781 VKTSVKKTQAKANPAAARAPSA 802
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 78.6 bits (192), Expect = 4e-14
Identities = 187/925 (20%), Positives = 326/925 (35%), Gaps = 127/925 (13%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 629
+ K +P A S +P + +P A T+VS+
Sbjct: 126 KAETEKAGK---TGNSMPHPATGKTVANLLSGKSP---------RKSAEPSANTTLVSET 173
Query: 630 AEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAAT----LVSQQAEEGLTLPQDSAMTPP 685
EEG ++P P + + S+ + ++++ + + +E+ L + SA
Sbjct: 174 EEEG-SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232
Query: 686 LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 745
P + + P P A V+ Q + G P++ + + + S + + AA
Sbjct: 233 TPGK----GATPAPPGKAGAVASQTKAGK--PEEDSES-----SSEESSDSEEETPAAKA 281
Query: 746 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATIVSQQAEEGLTLPQDSA 801
+ Q G T +A P + AP P A ++ E+ + ++S
Sbjct: 282 LLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 341
Query: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861
P Q AP+ AA+ + +G P P + T P A
Sbjct: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA---------PAPPRKTG------PAA 386
Query: 862 AATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV 921
A V +Q E+ + ++S S E LA ++ G +P +P
Sbjct: 387 AQVQVGKQEEDSRSSSEES-------------DSDREALAAMNAAQVKP-LGKSPQVKPA 432
Query: 922 ATMAQQEVGEALGPRPAPEEKNAALPT--VPEPAALDQVQQDDPQPAAEAGTPWAAQEDA 979
+TM +G+ GP P P + A P+ V + + ++ +++ P A
Sbjct: 433 STMGMGPLGKGAGPVP-PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 491
Query: 980 DSTLG--MEALSLPEPASGAGEEIAEALSRPGREACL---EARAHTGDGAKPDSPQKETL 1034
+ +LG ++A PA G ++ + E + E+ + D A DS +
Sbjct: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA--DSEEAPAA 549
Query: 1035 EVENQQEGGLKPLAQEHGPR--SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGK 1092
Q + LK + P+ + A+ P P + SPA ++G
Sbjct: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAG- 607
Query: 1093 STPEPTLPSAVATEASLDSCPESS-----VGAVSSLDRGCP--DAPAPTSAPTSQQPEPV 1145
T P S+ + E+ DS E + VG S+ +G A P Q PV
Sbjct: 608 GTQRPAEDSSSSEES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV 665
Query: 1146 L-----------------GLGSVEQPHEVPSVLGTPL---LQPPENLAKGQPSTPVDRPL 1185
L S E+ + +P + AK P+
Sbjct: 666 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Query: 1186 GPDPSAPGTLAGAALPP-------LEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQ 1238
SAPG + AA ++PP ++PQ +V P +P V
Sbjct: 726 KGTISAPGKVVTAAAQAKQRSPSKVKPPV----RNPQNSTVLARGPAS---VPSVGKAVA 778
Query: 1239 PAAAAVSGTTQPLGTGPRVSLSPH-SPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1297
AA A +G + G+ S S + L+ S + + P + P +P
Sbjct: 779 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 838
Query: 1298 AGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAP 1357
G G SA + + +DS S + SDS GE+ A + ++ P +
Sbjct: 839 PGKTGPSAAQAGKQDDSGS--------SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRS 890
Query: 1358 AGGSEETIAKAKQSRSEKKARKAMS 1382
G T A+A+ + + +KAR + S
Sbjct: 891 PAGPAATPAQAQAASTPRKARASES 915
Score = 59.3 bits (142), Expect = 3e-08
Identities = 157/768 (20%), Positives = 261/768 (33%), Gaps = 76/768 (9%)
Query: 328 PLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDL----SITEGMDEAFAFRDD 383
P EE+ ++ + G G+ S + + S+ +G +
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTG 671
Query: 384 TSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVS- 442
+ ++ +E+ +E S E A ++ SV+KT+ ++ A + GT+S
Sbjct: 672 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 731
Query: 443 --WAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT 500
V AA Q R + + + LA G S +V VA Q +
Sbjct: 732 PGKVVTAAAQAKQRSP-SKVKPPVRNPQNSTVLARGPASVPSVGK---AVATAAQAQTGP 787
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL--GQESVTAEKLPTPQEETSLTLC 558
+ EEE+DS E+ A P I L +ES PTP +T +
Sbjct: 788 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA 847
Query: 559 ----PDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLS 614
D + EE D + +A I P D P S P +
Sbjct: 848 QAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD---PNRSPAGPAATPAQAQAA 904
Query: 615 SAPKPVAA----ATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSA-PK--PVAAATLVS 667
S P+ A A S ++E+ +P +TP + + +A P+ P A+ S
Sbjct: 905 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 964
Query: 668 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 727
E P + + +S P AA +++Q+A E A T P
Sbjct: 965 SSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEA---QPPVARTQPSS 1021
Query: 728 LQDTDLSSAPKPVAAATLVSQQAEEGLTLP-----QDSAMTPPLPLQDTDLSSAPKPVAA 782
D+ + + P +T V + L P Q + P D S +
Sbjct: 1022 GVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEE 1081
Query: 783 ATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA--ATIVSQQAEEGLTLPQDS 840
Q A+ TL + +++T S+ V A +++S GLT P +S
Sbjct: 1082 DGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLT-PANS 1140
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSA-MTAPLPLQDTGPTSGPEP 899
+ P D+ S + A P +Q + PQ +A M +P T G E
Sbjct: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAK----PQQAAGMLSP-------KTGGKEA 1189
Query: 900 LAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAP-------------------E 940
+ TPQ + A + Q + + L +P P +
Sbjct: 1190 ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQ 1249
Query: 941 EKNAALPTVPEPAALD----QVQQDDPQPAAEAGTPWA-AQEDADSTLGMEALSLPEPAS 995
E+ + T E + + + QPAA TP + ++ + G EA PE S
Sbjct: 1250 ERKKVVDTTKESSRKGWESRKRKLSGDQPAAR--TPRSKKKKKLGAGEGGEASVSPEKTS 1307
Query: 996 GAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGG 1043
+ A+ G + + G D P++E + EGG
Sbjct: 1308 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1355
Score = 58.9 bits (141), Expect = 4e-08
Identities = 166/766 (21%), Positives = 270/766 (35%), Gaps = 136/766 (17%)
Query: 769 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL------PLQDTDLSSAPKPVAA 822
+D L + V+ S+ +EE ++A P + DL S+ K A
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 823 ATIVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSA 881
A + + G ++P + T L + +P A T VS+ EEG ++P A
Sbjct: 127 AE-TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-SVPAFGA 184
Query: 882 MTAPLPL---------QDTGPTSGPEPLAV-ATPQTLQAEAGCAPGTEPVATMAQQEVGE 931
P + +DT +S + V A+ + LQ A AP A+ G+
Sbjct: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAP--------AKGTPGK 236
Query: 932 ALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLP 991
G PAP K A+ + Q + P+ +E+ + ++ + + T +AL L
Sbjct: 237 --GATPAPPGKAGAVAS--------QTKAGKPEEDSESSSEESSDSE-EETPAAKAL-LQ 284
Query: 992 EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEH 1051
ASG ++ A S P +E+ + GA P P K V Q G + +Q
Sbjct: 285 AKASGKTSQVGAA-SAPAKESPRK-------GAAPAPPGKTGPAVAKAQAGKREEDSQSS 336
Query: 1052 GPRSALGGAREVPDAPPAACPEVSQARLLSPAREE-RGLSGKSTPEPTLPSAVATEASLD 1110
S P P+V A +PA+E R + + P T P+A +
Sbjct: 337 SEESDSEEEAPAQAKPSGKAPQVRAAS--APAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 394
Query: 1111 SCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPE 1170
S S DR +A + Q +P LG +P ++P
Sbjct: 395 EEDSRSSSEESDSDREA------LAAMNAAQVKP---LGK------------SPQVKPAS 433
Query: 1171 NLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGL 1230
+ G P+ + GP P PG + P P A + +S +E S G
Sbjct: 434 TMGMG----PLGKGAGPVP--PGKVG-----PATPSAQVGKWEEDSESSSEESSDSSDGE 482
Query: 1231 PPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP 1290
P V PA G +L K S AK
Sbjct: 483 VP--TAVAPAQEKSLGN-----------------ILQAKPTSSPAK-------------- 509
Query: 1291 PSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTV 1350
GP AGP + ++ ++S E S + S ++ +A + + PQT
Sbjct: 510 --GPPQKAGPVAVQVKAEKPMDNS--ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 565
Query: 1351 QCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLR-QIQGVTRITIQKSKNILFVIAK 1409
CP + S + +++ +KA A S G + G T+ + S + ++
Sbjct: 566 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS-----SE 620
Query: 1410 PDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK----------VPSEPSALVPESAP 1459
+ + V G+AK QV KAA+ K +P + V +
Sbjct: 621 ESDSEEEKTGLAVTVGQAKSVGKGLQV-KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA 679
Query: 1460 RPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRA 1505
+ E EEE + EE ++ A+AN + A+A A
Sbjct: 680 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Score = 57.0 bits (136), Expect = 1e-07
Identities = 210/1044 (20%), Positives = 350/1044 (33%), Gaps = 181/1044 (17%)
Query: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLAN-DPMIPAALLPFQGSLIFQVEAVEVTP 328
TP PP ++++ + + +E + ++ + PAA Q + V
Sbjct: 239 TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS 298
Query: 329 LSPEEEEEEAVADPDPGGD-------LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFR 381
+E + A PG AG+ EEDS S+S + + + A +
Sbjct: 299 APAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQ 358
Query: 382 -DDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGT 440
SA + +S A A + Q ++ + + EES + L A +
Sbjct: 359 VRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAA 418
Query: 441 VSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT 500
+ +PQ + G G V P T P QV
Sbjct: 419 QVKPLGKSPQVKPASTM---------GMGPLGKGAGPVPPGKVGPAT----PSAQVGKWE 465
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEE--TSLTLC 558
+ + EE +DS+ G+ A+A Q ++ + IL + ++ PQ+ ++ +
Sbjct: 466 EDSESSSEESSDSSDGEVPTAVAPAQ--EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
Query: 559 PDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK 618
+ P + E S A A + QAK L +PQ T P + +SA
Sbjct: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQ----TKACPKKTNTTASAK- 578
Query: 619 PVAAATIVSQQAEEGLTLPQDSVMTPPL------PLQDTELSSAPKPVAAATLVSQQAEE 672
VA + +Q + T + +P + P +D+ S S++ +
Sbjct: 579 -VAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESD--------SEEEKT 629
Query: 673 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTD 732
GL + A + LQ + +A PV + L Q +A P LP
Sbjct: 630 GLAVTVGQAKSVGKGLQ---VKAASVPVKGS------------LGQGTA--PVLP----- 667
Query: 733 LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEE 792
V Q+ E DS P Q +S K A A + +A
Sbjct: 668 -GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK--TSVKKTQAKANPAAARA-- 722
Query: 793 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL--PLQD 850
P +S+ K V AA Q++ S + PP+ P
Sbjct: 723 --------------PSAKGTISAPGKVVTAAAQAKQRSP--------SKVKPPVRNPQNS 760
Query: 851 TDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP--QTL 908
T L+ P V + A + T P++ + ++ +++ E LA P +T
Sbjct: 761 TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE---EESDSEEEAETLAQVKPSGKTH 817
Query: 909 QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAE 968
Q A AP E G P P K P+A +QDD ++E
Sbjct: 818 QIRAALAPAKE----------SPRKGAAPTPPGKTG-------PSAAQAGKQDDSGSSSE 860
Query: 969 AGTPWAAQEDADSTLGMEALSLPEPA--------SGAGEEI----AEALSRPGREACLEA 1016
+ D ++ + + + +P S AG A+A S P + E+
Sbjct: 861 E-----SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 915
Query: 1017 RAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQ 1076
A + +S ++ + G++ +P A P P+ S
Sbjct: 916 TARSSSS---ESEDEDVIPATQCLTPGIRT------------NVVTMPTAHPRIAPKASM 960
Query: 1077 ARLLSPAREERGLSGKSTPEP----------TLP------SAVATEASLDSCPESSVGAV 1120
A S R GK P +LP +A +AS P +
Sbjct: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1020
Query: 1121 SSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTP 1180
S +D PA + TS Q + G + +P ++P V + PE+ + S+
Sbjct: 1021 SGVDSAVGTLPATSPQSTSVQAK---GTNKLRKP-KLPEV--QQATKAPESSDDSEDSS- 1073
Query: 1181 VDRPLGPDPSAPGTLAGAALPPLEPPAP----CLCQDPQEDSVEDE--EPPGSLGLPPPQ 1234
D G + G + L P P L ++ +S ED+ P SL
Sbjct: 1074 -DSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMT 1132
Query: 1235 AGVQPAAAAVSGTTQPLGTGPRVS 1258
G+ PA + S T L + P VS
Sbjct: 1133 PGLTPANSQASKATPKLDSSPSVS 1156
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 78.6 bits (192), Expect = 4e-14
Identities = 187/925 (20%), Positives = 326/925 (35%), Gaps = 127/925 (13%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 629
+ K +P A S +P + +P A T+VS+
Sbjct: 126 KAETEKAGK---TGNSMPHPATGKTVANLLSGKSP---------RKSAEPSANTTLVSET 173
Query: 630 AEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAAT----LVSQQAEEGLTLPQDSAMTPP 685
EEG ++P P + + S+ + ++++ + + +E+ L + SA
Sbjct: 174 EEEG-SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232
Query: 686 LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 745
P + + P P A V+ Q + G P++ + + + S + + AA
Sbjct: 233 TPGK----GATPAPPGKAGAVASQTKAGK--PEEDSES-----SSEESSDSEEETPAAKA 281
Query: 746 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATIVSQQAEEGLTLPQDSA 801
+ Q G T +A P + AP P A ++ E+ + ++S
Sbjct: 282 LLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 341
Query: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861
P Q AP+ AA+ + +G P P + T P A
Sbjct: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA---------PAPPRKTG------PAA 386
Query: 862 AATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV 921
A V +Q E+ + ++S S E LA ++ G +P +P
Sbjct: 387 AQVQVGKQEEDSRSSSEES-------------DSDREALAAMNAAQVKP-LGKSPQVKPA 432
Query: 922 ATMAQQEVGEALGPRPAPEEKNAALPT--VPEPAALDQVQQDDPQPAAEAGTPWAAQEDA 979
+TM +G+ GP P P + A P+ V + + ++ +++ P A
Sbjct: 433 STMGMGPLGKGAGPVP-PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 491
Query: 980 DSTLG--MEALSLPEPASGAGEEIAEALSRPGREACL---EARAHTGDGAKPDSPQKETL 1034
+ +LG ++A PA G ++ + E + E+ + D A DS +
Sbjct: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA--DSEEAPAA 549
Query: 1035 EVENQQEGGLKPLAQEHGPR--SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGK 1092
Q + LK + P+ + A+ P P + SPA ++G
Sbjct: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAG- 607
Query: 1093 STPEPTLPSAVATEASLDSCPESS-----VGAVSSLDRGCP--DAPAPTSAPTSQQPEPV 1145
T P S+ + E+ DS E + VG S+ +G A P Q PV
Sbjct: 608 GTQRPAEDSSSSEES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV 665
Query: 1146 L-----------------GLGSVEQPHEVPSVLGTPL---LQPPENLAKGQPSTPVDRPL 1185
L S E+ + +P + AK P+
Sbjct: 666 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Query: 1186 GPDPSAPGTLAGAALPP-------LEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQ 1238
SAPG + AA ++PP ++PQ +V P +P V
Sbjct: 726 KGTISAPGKVVTAAAQAKQRSPSKVKPPV----RNPQNSTVLARGPAS---VPSVGKAVA 778
Query: 1239 PAAAAVSGTTQPLGTGPRVSLSPH-SPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1297
AA A +G + G+ S S + L+ S + + P + P +P
Sbjct: 779 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 838
Query: 1298 AGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAP 1357
G G SA + + +DS S + SDS GE+ A + ++ P +
Sbjct: 839 PGKTGPSAAQAGKQDDSGS--------SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRS 890
Query: 1358 AGGSEETIAKAKQSRSEKKARKAMS 1382
G T A+A+ + + +KAR + S
Sbjct: 891 PAGPAATPAQAQAASTPRKARASES 915
Score = 60.5 bits (145), Expect = 1e-08
Identities = 159/768 (20%), Positives = 263/768 (34%), Gaps = 77/768 (10%)
Query: 328 PLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDL----SITEGMDEAFAFRDD 383
P EE+ ++ + G G+ S + + S+ +G +
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTG 671
Query: 384 TSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVS- 442
+ ++ +E+ +E S E A ++ SV+KT+ ++ A + GT+S
Sbjct: 672 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 731
Query: 443 --WAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT 500
V AA Q R + + + LA G S +V VA Q +
Sbjct: 732 PGKVVTAAAQAKQRSP-SKVKPPVRNPQNSTVLARGPASVPSVGK---AVATAAQAQTGP 787
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL--GQESVTAEKLPTPQEETSLTLC 558
+ EEE+DS E+ A P I L +ES PTP +T +
Sbjct: 788 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA 847
Query: 559 ----PDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLS 614
D + EE D + +A I P D P S P +
Sbjct: 848 QAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD---PNRSPAGPAATPAQAQAA 904
Query: 615 SAPKPVAA----ATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSA-PK--PVAAATLVS 667
S P+ A A S ++E+ +P +TP + + +A P+ P A+ S
Sbjct: 905 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 964
Query: 668 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 727
E P + + +S P AA +++Q+A E A T P
Sbjct: 965 SSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEA---QPPVARTQPSS 1021
Query: 728 LQDTDLSSAPKPVAAATLVSQQAEEGLTLP-----QDSAMTPPLPLQDTDLSSAPKPVAA 782
D+ + + P +T V + L P Q + P D S +
Sbjct: 1022 GVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEE 1081
Query: 783 ATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA--ATIVSQQAEEGLTLPQDS 840
Q A+ TL + T L +++T S+ V A +++S GLT P +S
Sbjct: 1082 DGEGPQGAKSAHTLGPTPSRTETL-VEETAAESSEDDVVAPSQSLLSGYMTPGLT-PANS 1139
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSA-MTAPLPLQDTGPTSGPEP 899
+ P D+ S + A P +Q + PQ +A M +P T G E
Sbjct: 1140 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAK----PQQAAGMLSP-------KTGGKEA 1188
Query: 900 LAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAP-------------------E 940
+ TPQ + A + Q + + L +P P +
Sbjct: 1189 ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQ 1248
Query: 941 EKNAALPTVPEPAALD----QVQQDDPQPAAEAGTPWA-AQEDADSTLGMEALSLPEPAS 995
E+ + T E + + + QPAA TP + ++ + G EA PE S
Sbjct: 1249 ERKKVVDTTKESSRKGWESRKRKLSGDQPAAR--TPRSKKKKKLGAGEGGEASVSPEKTS 1306
Query: 996 GAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGG 1043
+ A+ G + + G D P++E + EGG
Sbjct: 1307 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1354
Score = 58.9 bits (141), Expect = 4e-08
Identities = 166/766 (21%), Positives = 270/766 (35%), Gaps = 136/766 (17%)
Query: 769 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL------PLQDTDLSSAPKPVAA 822
+D L + V+ S+ +EE ++A P + DL S+ K A
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 823 ATIVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSA 881
A + + G ++P + T L + +P A T VS+ EEG ++P A
Sbjct: 127 AE-TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-SVPAFGA 184
Query: 882 MTAPLPL---------QDTGPTSGPEPLAV-ATPQTLQAEAGCAPGTEPVATMAQQEVGE 931
P + +DT +S + V A+ + LQ A AP A+ G+
Sbjct: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAP--------AKGTPGK 236
Query: 932 ALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLP 991
G PAP K A+ + Q + P+ +E+ + ++ + + T +AL L
Sbjct: 237 --GATPAPPGKAGAVAS--------QTKAGKPEEDSESSSEESSDSE-EETPAAKAL-LQ 284
Query: 992 EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEH 1051
ASG ++ A S P +E+ + GA P P K V Q G + +Q
Sbjct: 285 AKASGKTSQVGAA-SAPAKESPRK-------GAAPAPPGKTGPAVAKAQAGKREEDSQSS 336
Query: 1052 GPRSALGGAREVPDAPPAACPEVSQARLLSPAREE-RGLSGKSTPEPTLPSAVATEASLD 1110
S P P+V A +PA+E R + + P T P+A +
Sbjct: 337 SEESDSEEEAPAQAKPSGKAPQVRAAS--APAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 394
Query: 1111 SCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPE 1170
S S DR +A + Q +P LG +P ++P
Sbjct: 395 EEDSRSSSEESDSDREA------LAAMNAAQVKP---LGK------------SPQVKPAS 433
Query: 1171 NLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGL 1230
+ G P+ + GP P PG + P P A + +S +E S G
Sbjct: 434 TMGMG----PLGKGAGPVP--PGKVG-----PATPSAQVGKWEEDSESSSEESSDSSDGE 482
Query: 1231 PPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP 1290
P V PA G +L K S AK
Sbjct: 483 VP--TAVAPAQEKSLGN-----------------ILQAKPTSSPAK-------------- 509
Query: 1291 PSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTV 1350
GP AGP + ++ ++S E S + S ++ +A + + PQT
Sbjct: 510 --GPPQKAGPVAVQVKAEKPMDNS--ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 565
Query: 1351 QCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLR-QIQGVTRITIQKSKNILFVIAK 1409
CP + S + +++ +KA A S G + G T+ + S + ++
Sbjct: 566 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS-----SE 620
Query: 1410 PDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK----------VPSEPSALVPESAP 1459
+ + V G+AK QV KAA+ K +P + V +
Sbjct: 621 ESDSEEEKTGLAVTVGQAKSVGKGLQV-KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA 679
Query: 1460 RPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRA 1505
+ E EEE + EE ++ A+AN + A+A A
Sbjct: 680 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Score = 57.8 bits (138), Expect = 8e-08
Identities = 209/1041 (20%), Positives = 348/1041 (33%), Gaps = 176/1041 (16%)
Query: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLAN-DPMIPAALLPFQGSLIFQVEAVEVTP 328
TP PP ++++ + + +E + ++ + PAA Q + V
Sbjct: 239 TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS 298
Query: 329 LSPEEEEEEAVADPDPGGD-------LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFR 381
+E + A PG AG+ EEDS S+S + + + A +
Sbjct: 299 APAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQ 358
Query: 382 -DDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGT 440
SA + +S A A + Q ++ + + EES + L A +
Sbjct: 359 VRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAA 418
Query: 441 VSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT 500
+ +PQ + G G V P T P QV
Sbjct: 419 QVKPLGKSPQVKPASTM---------GMGPLGKGAGPVPPGKVGPAT----PSAQVGKWE 465
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEE--TSLTLC 558
+ + EE +DS+ G+ A+A Q ++ + IL + ++ PQ+ ++ +
Sbjct: 466 EDSESSSEESSDSSDGEVPTAVAPAQ--EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
Query: 559 PDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK 618
+ P + E S A A + QAK L +PQ T P + +SA
Sbjct: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQ----TKACPKKTNTTASAK- 578
Query: 619 PVAAATIVSQQAEEGLTLPQDSVMTPPL------PLQDTELSSAPKPVAAATLVSQQAEE 672
VA + +Q + T + +P + P +D+ S S++ +
Sbjct: 579 -VAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESD--------SEEEKT 629
Query: 673 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTD 732
GL + A + LQ + +A PV + L Q +A P LP
Sbjct: 630 GLAVTVGQAKSVGKGLQ---VKAASVPVKGS------------LGQGTA--PVLP----- 667
Query: 733 LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEE 792
V Q+ E DS P Q +S K A A + +A
Sbjct: 668 -GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK--TSVKKTQAKANPAAARA-- 722
Query: 793 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL--PLQD 850
P +S+ K V AA Q++ S + PP+ P
Sbjct: 723 --------------PSAKGTISAPGKVVTAAAQAKQRSP--------SKVKPPVRNPQNS 760
Query: 851 TDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP--QTL 908
T L+ P V + A + T P++ + ++ +++ E LA P +T
Sbjct: 761 TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE---EESDSEEEAETLAQVKPSGKTH 817
Query: 909 QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAE 968
Q A AP E G P P K P+A +QDD ++E
Sbjct: 818 QIRAALAPAKE----------SPRKGAAPTPPGKTG-------PSAAQAGKQDDSGSSSE 860
Query: 969 AGTPWAAQEDADSTLGMEALSLPEPA--------SGAGEEI----AEALSRPGREACLEA 1016
+ D ++ + + + +P S AG A+A S P + E+
Sbjct: 861 E-----SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 915
Query: 1017 RAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQ 1076
A + +S ++ + G++ +P A P P+ S
Sbjct: 916 TARSSSS---ESEDEDVIPATQCLTPGIRT------------NVVTMPTAHPRIAPKASM 960
Query: 1077 ARLLSPAREERGLSGKSTPEP----------TLP------SAVATEASLDSCPESSVGAV 1120
A S R GK P +LP +A +AS P +
Sbjct: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1020
Query: 1121 SSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTP 1180
S +D PA + TS Q + G + +P ++P V + PE+ + S+
Sbjct: 1021 SGVDSAVGTLPATSPQSTSVQAK---GTNKLRKP-KLPEV--QQATKAPESSDDSEDSSD 1074
Query: 1181 VDRPLGPDPSAP-GTLAGAALPPLEPPAPCLCQDPQEDSVEDE--EPPGSLGLPPPQAGV 1237
D P G + L P L ++ +S ED+ P SL G+
Sbjct: 1075 SSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGL 1134
Query: 1238 QPAAAAVSGTTQPLGTGPRVS 1258
PA + S T L + P VS
Sbjct: 1135 TPANSQASKATPKLDSSPSVS 1155
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 77.4 bits (189), Expect = 1e-13
Identities = 309/1430 (21%), Positives = 464/1430 (32%), Gaps = 205/1430 (14%)
Query: 66 QPEGASWDAGPGGAPSAWADPGEGGPSPM----LLPEGLSSQALSTEAPLPATLEPRIVM 121
+ G + + P + S G PS P G + S E ++ R
Sbjct: 780 EASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSH 839
Query: 122 GEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPT 181
++ LLS A+ A+ G +S P + + S P S +P ++P
Sbjct: 840 TTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQ 899
Query: 182 KTTYALLPA------CGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCS 235
+T A D ++ D PP PS IT+ G +SP
Sbjct: 900 ETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPS---ITSTG---LTSPQTE 953
Query: 236 LSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFF 295
L+P SG G + +++ TP P + SS S ++ H
Sbjct: 954 THTLSP-------SGSGKTFTTALISN------ATPLPVTYASSASTGHTTPL----HVT 996
Query: 296 DLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEED 355
D ++ P LP P++ E P P + D
Sbjct: 997 DASSVSTGHATP---LPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGD 1053
Query: 356 ST-------SASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGE 408
ST S++ ++ L +T + D T +D+ SAS A +
Sbjct: 1054 STPLPVTDTSSASTGHVTPLPVTSLSSASTG--DTTPLPVTDTSSASTGHATSLPVTDTS 1111
Query: 409 PHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEV 468
+ V T S G A L D + P + S Q V
Sbjct: 1112 SVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPV 1171
Query: 469 TEEGLALGQESTATVTP---------HTLQVAPGLQVEVATRVTPQAG-----EEETDST 514
T +L ST TP T P L + ++ T A + + ST
Sbjct: 1172 T----SLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVST 1227
Query: 515 AGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLP 574
S + +P + G + L VT + + TSL + S + + L +
Sbjct: 1228 DHATSLPVTIPSAASTGHTTPL---PVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVT 1284
Query: 575 SGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA------PKPVAAATIVSQ 628
S + + P +T P ++ PL T LSSA P PV + + S
Sbjct: 1285 S-TSSASTGHVTPLH----VTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAST 1339
Query: 629 QAEEGLTLPQDSVMTP--PLPLQDTELSSA------PKPVAAATLVSQQAEEGL--TLPQ 678
L + S ++ PL T+ SSA P PV + + VS L T P
Sbjct: 1340 GDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPS 1399
Query: 679 DSAMTPPLPLQDTDLSSA------PKPVAAATLVSQQAEEGL--TLPQDSAMTPPLPLQD 730
++ PL TD SSA P PV A+ VS L T+P ++ PL
Sbjct: 1400 SASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPV 1459
Query: 731 TDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK--PVAAATIVSQ 788
TD SSA A + LV+ T + T PLP+ T +S P+ + S
Sbjct: 1460 TDTSSASTGQATSLLVTD------TSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSA 1513
Query: 789 QAEEGLTLPQDSAM------TPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGL--TL 836
LP S T PLP+ +S P PV A+ VS L T
Sbjct: 1514 STGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTS 1573
Query: 837 PQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDT--GPT 894
P ++ PL TD SSA K PV+ + + T PLP+ DT T
Sbjct: 1574 PSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSS------ASTGHTTPLPVTDTSSAST 1627
Query: 895 SGPEPLAV----------ATPQTLQAEAGCAPGTE---PVATMAQQEVGEA-----LGPR 936
PL V ATP + + + + G PV + + G A G
Sbjct: 1628 GDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLS 1687
Query: 937 PAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAG-------TPWAAQEDADSTLGMEALS 989
A + LP +A Q P P TP + ++ G +
Sbjct: 1688 SATTDDTTRLPVTDVSSA--STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPL 1745
Query: 990 LPEPASGAGEEIAEALSRPGREACLEARAHT--------GDGAKPDSPQKETLEVENQQE 1041
L AS A +A P + + AH + D+ + +V +
Sbjct: 1746 LVTDASSA--STGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSAST 1803
Query: 1042 GGLKPLAQEHGPRSALGGAREVP--DAPPAACPEVSQARLLSPAREERGLSGKSTPEPTL 1099
G PL ++ G +P DA A+ + + + P+ SG +T P
Sbjct: 1804 GQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSAS---SGHTTSLPVT 1860
Query: 1100 PSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ-QPEPVLGLGSVEQPH--- 1155
++ + S + +VS+ D SA T P V SV H
Sbjct: 1861 DASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATS 1920
Query: 1156 -EVPSVLG------TPLLQPPENLAKGQPSTPV------DRPLGPDPSAPGTLAGAALPP 1202
V S+ TPL + A +TP+ P G S P T A +
Sbjct: 1921 LPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTG 1980
Query: 1203 LEPPAPCLCQDPQEDSVEDEEP-------PGSLGLPPPQAGVQPAAAAVSGTTQ-PLGTG 1254
P P D S P S G P ++A+ TT P+
Sbjct: 1981 HATPLP--VTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDT 2038
Query: 1255 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDS 1314
S +PL ++S+ D P V PS + G + P D S
Sbjct: 2039 SSASTGQDTPLPVTSLSSVSTGDTT-----PLPVTSPSSAST-----GHATPLLVTDASS 2088
Query: 1315 LEEDSPRAL---GSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGS 1361
+ +L + S H + D + T P +P+ S
Sbjct: 2089 VSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSAS 2138
Score = 73.2 bits (178), Expect = 2e-12
Identities = 235/1033 (22%), Positives = 343/1033 (33%), Gaps = 130/1033 (12%)
Query: 25 SCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPGGA---PS 81
S AT +L D P H+ S P P + G A P
Sbjct: 3176 SVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPV 3235
Query: 82 AWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRD 141
G + L +SS + PLP T + G+ + SP +A T
Sbjct: 3236 TGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSAST---- 3291
Query: 142 QEGGHASPDPPPELCSQGD-LSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDS 200
GHA+P P S + P P S T +TP T D +
Sbjct: 3292 ---GHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVT-----------DTSSA 3337
Query: 201 EAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMV 260
L + P+S S + T + SS S + P G S +P
Sbjct: 3338 STGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTD 3397
Query: 261 DERELHPAGTPEPPSSESSLSADSSS-------SWGQEGHFFDLDFLANDPMIPAALLPF 313
TP P +S SS+S ++ S G L + + P
Sbjct: 3398 TSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPL 3457
Query: 314 QGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEG 373
+ V TPL + + GD D++SAS Q+ + L +T
Sbjct: 3458 LVTDASSVSTGHATPLPVTDTSSAST------GDTTRLPVTDTSSASTGQA-TPLPVTSL 3510
Query: 374 MDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKG 433
+ + D T +D+ S S A + + + V T S G A
Sbjct: 3511 --SSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATP 3568
Query: 434 LQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPG 493
L + S + P + +S VT A ST VTP +
Sbjct: 3569 LPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSA----STGHVTPLPVTSTSS 3624
Query: 494 LQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQ 550
AT + + A S A P P + S G + VT +
Sbjct: 3625 ASTGHATPLLV--------TDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTG 3676
Query: 551 EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAA-ATIVPRQAKEDLTLPQDSAMTPPLPLQ 609
+ T L + S + + L + AT +P +T+P + +PL
Sbjct: 3677 QATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLP------VTIPSSVSTGDTMPLP 3730
Query: 610 DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSA----PKPVAAATL 665
T SSA A V+ GL+ TP LP+ DT +S P PV +
Sbjct: 3731 VTSPSSASTGHATPLPVT-----GLSSASTGDTTP-LPVTDTSSASTRHATPLPVTDTSS 3784
Query: 666 VSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSA----PKPVAAATLVSQQAEEGLTLP 717
S L + S+ + PLP+ T +S P PV + VS L +
Sbjct: 3785 ASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVT 3844
Query: 718 QDSAMTP----PLPLQDTDLSSA----PKPVAAATLVSQQAEEGLTLPQDSAMTP----P 765
S+ + PLP+ DT S P PV + + VS L + S+ + P
Sbjct: 3845 SRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATP 3904
Query: 766 LPLQDTDLSSA----PKPVAAATIVSQQAEEGL--TLPQDSAMTPPLPLQDTDLSSA--- 816
+P+ T +S P PV A+ +S L T P ++ L TD SSA
Sbjct: 3905 VPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTG 3964
Query: 817 ---PKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA------PKPVAAATPVS 867
P P+ + + VS + T PLP+ TD SSA P PV + + VS
Sbjct: 3965 HATPLPLTSLSSVS------------TGDTTPLPV--TDTSSASTGQATPLPVTSLSSVS 4010
Query: 868 QQAEEGL--TLPQ--DSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVAT 923
L T+P S T LP+ D S + T A G PV
Sbjct: 4011 TGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPL-PVTD 4069
Query: 924 MAQQEVGEALGPRPAPEEKNAAL-PTVPEP-AALDQVQQDDPQPAAEAGTPWAAQEDADS 981
+ G A P P + +A+ P P +L V P A + A+ +DS
Sbjct: 4070 TSSASTGHAT-PLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDS 4128
Query: 982 TLGMEALSLPEPA 994
L ME + P+
Sbjct: 4129 PLKMETPGMTTPS 4141
Score = 72.8 bits (177), Expect = 2e-12
Identities = 137/589 (23%), Positives = 206/589 (34%), Gaps = 91/589 (15%)
Query: 603 TPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSVM----TPPLPLQDTELS 654
T PLP DT S P V A+ VS L + S T PLP+ DT +
Sbjct: 2462 TTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSA 2521
Query: 655 SA----PKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSA----PKPVAA 702
S P PV A+ +S + L + S+ + LP+ DT +S P PV +
Sbjct: 2522 STGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTS 2581
Query: 703 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAM 762
+ S + T PLP+ DT +S + + A G
Sbjct: 2582 TSSAS------------TGDTTPLPVTDTYSASTGQATPLPVTDTSSASTG--------D 2621
Query: 763 TPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSAM----TPPLPLQDTD-- 812
T PLP+ DT +S P PV + VS L + S+ T PLP+ D
Sbjct: 2622 TTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSV 2681
Query: 813 ----LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQ 868
+S P A++ +T+P ++ PL TD SS A + PV+
Sbjct: 2682 STGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTD 2741
Query: 869 QAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTE---PVATMA 925
+ + PLP+ D S ATP L + + + G PV +
Sbjct: 2742 ASS------VSTGHATPLPVTDASSVS----TGHATPLPLTSLSSVSTGDTTPLPVTDTS 2791
Query: 926 QQEVGEALGPRPAPEEKNAAL-PTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLG 984
G+A P P + + T P P D A+ D S
Sbjct: 2792 SASTGQAT-PLPVTSLSSVSTGDTTPLPVT-------DTSSASTGHATSLPVTDTSSAST 2843
Query: 985 MEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGL 1044
A LP+ + S A L T + + + + G
Sbjct: 2844 GHATPLPD---------TDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHA 2894
Query: 1045 KPLAQEHGPRSALGGAREVP--DAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSA 1102
PL ++ G A +P D A+ + + SP+ +G +TP P ++
Sbjct: 2895 TPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSAS---TGHATPLPVTDTS 2951
Query: 1103 VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ-QPEPVLGLGS 1150
A+ P +S+ +VS+ D +P+SA T P PV S
Sbjct: 2952 SASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSS 3000
Score = 72.8 bits (177), Expect = 2e-12
Identities = 256/1186 (21%), Positives = 384/1186 (32%), Gaps = 178/1186 (15%)
Query: 90 GPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASP 149
G + +L SS ++ LP T I G T + SP +A T GHA+P
Sbjct: 2860 GHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSAST-------GHATP 2912
Query: 150 DPPPELCSQGDLSV-PSPPPDPDSFFTPPSTP---TKTTYALLPACGPHGDARDSEAELR 205
P + S P P S T +TP T T+ A P S
Sbjct: 2913 LPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTG 2972
Query: 206 DE--LLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDER 263
D L + P+S S + T + SS S + P S +P
Sbjct: 2973 DTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSS 3032
Query: 264 ELHPAGTPEPPSSESSLSAD-------SSSSWGQEGHFFDLDFLANDPMIPAALLPFQGS 316
TP P +S SS+S +S S GH L P +
Sbjct: 3033 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVT 3092
Query: 317 LIFQVEAVEVTPL---SPEEEEE-EAVADPDPGGDLAGEGEEDS-----TSASFLQSLSD 367
+ V + TPL SP A + P A G+ S TS+++ +
Sbjct: 3093 SLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTS 3152
Query: 368 LSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEES 427
L +T+ + D T +++ S S A + + V S
Sbjct: 3153 LPVTDTSSSSTG--DTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSAS 3210
Query: 428 GGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHT 487
G + D + A P + S VT+ A ++T +T
Sbjct: 3211 TGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNT 3270
Query: 488 LQVAPG--LQVEVATRVTPQAGEEE----TDSTAGQESAAMAMPQPSQEGISEILGQESV 541
V+ G + + V + + G T +++ A +P S S
Sbjct: 3271 SSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSAS-------- 3322
Query: 542 TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDL-TLPQDS 600
T P P +TS D+ L +G TI + D TLP
Sbjct: 3323 TGHTTPLPVTDTSSASTGDTTP-LPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTG 3381
Query: 601 AMTP------PLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQD 650
A + PLP+ DT S P PV + + VS T PLP+ D
Sbjct: 3382 ASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGD------------TTPLPVTD 3429
Query: 651 TELSSA----PKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDT----------- 691
+S P PV + + VS L + S+++ PLP+ DT
Sbjct: 3430 ASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRL 3489
Query: 692 ---DLSSA------PKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDT------D 732
D SSA P PV + + VS L + S+++ PLP+ DT D
Sbjct: 3490 PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGD 3549
Query: 733 LSSAPKPVAAATLVSQQAEEGLTLPQDSAM--TPPLPLQDTDLSSA-------------- 776
+ P ++ Q +T+P S+ T PLP+ T S
Sbjct: 3550 TTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSA 3609
Query: 777 ------PKPVAAATIVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSA----PKPVAA 822
P PV + + S L + S+++ PLP+ D +S P PV
Sbjct: 3610 STGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTD 3669
Query: 823 ATIVSQQAEEGLTLPQDSAM----TPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ 878
+ S L + S++ T PLP+ TD SSA A PV T+P
Sbjct: 3670 TSSASTGQATPLPVTSLSSVSTGDTTPLPV--TDASSASTGHATPLPV--------TIPS 3719
Query: 879 DSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPA 938
+ +PL T P+S A P T + A T T P P
Sbjct: 3720 SVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPV 3779
Query: 939 PEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAG 998
+ +A+ D T ++ D+T P P +
Sbjct: 3780 TDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTT--------PLPVTDTS 3831
Query: 999 E-EIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSAL 1057
A S P + +R+ G P +T V G PL +
Sbjct: 3832 SVSTGHATSLP-----VTSRSSASTGHATPLPVTDTSSVST---GHATPLPVTSTSSVST 3883
Query: 1058 GGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEP-----TLPSAVATEASLDSC 1112
G A +P P++ A + +G +TP P +L + AT + S
Sbjct: 3884 GHATPLPVTSPSSA-STGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSP 3942
Query: 1113 PESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVP 1158
+S G S+L P A +++ P P+ L SV P
Sbjct: 3943 SSASRGDTSTL----PVTDASSASTGHATPLPLTSLSSVSTGDTTP 3984
Score = 71.2 bits (173), Expect = 7e-12
Identities = 283/1283 (22%), Positives = 423/1283 (32%), Gaps = 171/1283 (13%)
Query: 84 ADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQE 143
A G+ P P+ P SS + PLP T + G T + +A T
Sbjct: 1321 ASTGDTMPLPVTSP---SSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSAST------ 1371
Query: 144 GGHASPDPPPELCS--QGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACG-----PHGD 196
G A+P P L S GD + P P P S T +TP T + G P D
Sbjct: 1372 -GQATPLPVTSLSSVSTGD-TTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTD 1429
Query: 197 ARDSEAELRDELLDSPPASPSGSYITA--DGDSWASSPSCSLSLLAP-----AEGLDFPS 249
A + L + P++ S + T D+ ++S + SLL + G P
Sbjct: 1430 ASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPL 1489
Query: 250 GWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAA 309
+ S LH + ++ +S S G L +
Sbjct: 1490 PVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGD 1549
Query: 310 LLPFQGSLIFQVEAVEVTPLSPEEEEEEAVAD--PDPGGDLAGEGEEDSTSASFLQSLSD 367
P + V TPL + P P D + + D+T L S
Sbjct: 1550 TTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTP---LPVTSP 1606
Query: 368 LSITEGMDEAFAFRDDTSAASSDS------DSASYAEADDERLYSGEPHAQAT--LLQDS 419
S + G D +SA++ D+ +++S + L+ P + +T
Sbjct: 1607 SSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLP 1666
Query: 420 VQKTEEESGGGAKGLQAQDGTVSWAVEAA--PQTSDRGAYLSQRQELISEVTEEGLALGQ 477
V T S G A L + + + P T A Q L VT +L
Sbjct: 1667 VTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPL--PVT----SLSS 1720
Query: 478 ESTATVTP---------HTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPS 528
ST TP T +P L + ++ T QA T+ S A A P P
Sbjct: 1721 VSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSV-STAHATPLP- 1778
Query: 529 QEGISEILGQESVTAEKLPTPQEETSLT-----LCPDSPQNLKEEGGLDLP---SGRKPV 580
++ + + +LP ++ T L SP + LP +
Sbjct: 1779 ---VTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSAST 1835
Query: 581 AAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 640
T +P +T+P ++ L TD SS A + +V+ + +
Sbjct: 1836 GDTTSLP------VTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVS------T 1883
Query: 641 VMTPPLPLQDTELSSA----PKPVAAATLVSQQAEEGLTLPQDSAM----TPPLPLQDTD 692
T PLP+ DT +S P V A+ VS L + S+ T PLP+
Sbjct: 1884 GDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPS 1943
Query: 693 LSSA----PKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSA----PKPV 740
+S+ P PV A+ V L + S+++ PLP+ D S P PV
Sbjct: 1944 SASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPV 2003
Query: 741 AAATLVSQQAEEGLTLPQDSAM----TPPLPLQDTDLSSA----PKPVAAATIVSQQAEE 792
+ VS L + S+ T PLP+ DT +S P PV + + VS
Sbjct: 2004 TDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTT 2063
Query: 793 GL--TLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQD 850
L T P ++ PL TD SS A + +V+ + +T L
Sbjct: 2064 PLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLST 2123
Query: 851 TDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQA 910
D + P PV + + S + T PLP+ DT S ++ T A
Sbjct: 2124 GD--TTPLPVTSPSSAS------------TGDTTPLPVTDTSSVSTGHATSLPVTDTSSA 2169
Query: 911 EAGCA---PGTE------------PVATMAQQEVGEALGPRPAPEEKNA----ALPTVPE 951
G A P T+ PV + G+A P P +A A+P +
Sbjct: 2170 STGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQAT-PLPVTSPSSASTGHAIPLLVT 2228
Query: 952 PAALDQVQQDDPQP------AAEAGTPWAAQEDADSTLGMEALSLPEPASGA---GEEIA 1002
+ Q P P A+ T DA S A SLP + + G+
Sbjct: 2229 DTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTP 2288
Query: 1003 EALSRPGREACLEAR-AHTGDGAKPDSPQKETLEV---ENQQEGGLKPLAQEHGPRSALG 1058
++ P + A H D + + L V + G PL P SA
Sbjct: 2289 LPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVT-SPSSAST 2347
Query: 1059 GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVG 1118
G A+ L SG +TP P ++ A+ P +
Sbjct: 2348 GHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTS 2407
Query: 1119 AVSSLDRGCPDAPAPTSAPTSQQPE-PVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQP 1177
+ S+ +SA T PV + S H TPL + A
Sbjct: 2408 SASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGH------ATPLPVTSTSSASTGD 2461
Query: 1178 STPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGV 1237
+TP+ G D S+ T G P L A + S G P V
Sbjct: 2462 TTPLP---GTDTSSVST--GHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTP-LPV 2515
Query: 1238 QPAAAAVSGTTQPLGTGPRVSLS 1260
+A +G T PL SLS
Sbjct: 2516 TDTPSASTGDTTPLPVTNASSLS 2538
Score = 69.3 bits (168), Expect = 3e-11
Identities = 257/1173 (21%), Positives = 380/1173 (32%), Gaps = 179/1173 (15%)
Query: 49 PSHLALTFLPSKPGARPQPEGASWDAGPGGAP------SAWADPGEGGPSPMLLPEGLSS 102
P + T S P P ++ A G A ++ A G+ P P+ SS
Sbjct: 2576 PLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVT---DTSS 2632
Query: 103 QALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLS 162
+ PLP T + G T + SP +A T GH +P P + S
Sbjct: 2633 ASTGHATPLPVTNTSSVSTGHATPLHVTSPSSAST-------GHTTPLPVTDASSVSTGH 2685
Query: 163 VPS-PPPDPDSFFTPPSTPTKTTYALLPACG-----PHGDARDSEAELRDELLDSPPASP 216
S P D S FT +T T + G P DA L + +S
Sbjct: 2686 ATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSV 2745
Query: 217 SGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSS 276
S + T + ASS S + P L S +P TP P +S
Sbjct: 2746 STGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTS 2805
Query: 277 ESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEE 336
SS+S ++ LP + P++
Sbjct: 2806 LSSVSTGDTTP-----------------------LPVTDTSSASTGHATSLPVTDTSSAS 2842
Query: 337 EAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASY 396
A P P D + ST + L ++D S + + TS +D+ S S
Sbjct: 2843 TGHATPLPDTDTSSA----STGHATLLPVTDTS-------SASIGHATSLPVTDTSSIST 2891
Query: 397 AEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGA 456
A + S + V T S G A L + + A P +
Sbjct: 2892 GHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTS 2951
Query: 457 YLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAG 516
S VT +L ST TP + +P T P TD+++
Sbjct: 2952 SASTGHATPLPVT----SLSSVSTGDTTPLPV-TSPSSASTGHTTPLP-----VTDTSSA 3001
Query: 517 QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLP-S 575
A A+P S S T + P P +TS + LP +
Sbjct: 3002 STGQATALPVTSTSSAS--------TGDTTPLPVTDTS---------SASTGQATPLPVT 3044
Query: 576 GRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA------PKPVAAATIVSQQ 629
V+ P +T P ++ PL TD SSA P PV + + VS
Sbjct: 3045 SLSSVSTGDTTPL----PVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTG 3100
Query: 630 AEEGLTLPQDSVMT----PPLPLQDTELSSAPKPVAAATLVSQQAEEG------LTLPQD 679
L + S + LP+ DT +S + + A G +T
Sbjct: 3101 DTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSS 3160
Query: 680 SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEG--------LTLPQDSAM--TPPLPLQ 729
S+ PL T+ SS A LV+ + +T P ++ T P+P+
Sbjct: 3161 SSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVT 3220
Query: 730 DTDLSS----APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA------PKP 779
DT S P PV + S + T LP+ TD+SSA P P
Sbjct: 3221 DTSSVSTGHATPLPVTGLSSAS------------TGDTTRLPV--TDISSASTGQATPLP 3266
Query: 780 VAAATIVSQQAEEGL--TLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP 837
V + VS L T P ++ PL T SSA A V+ T
Sbjct: 3267 VTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTS------TSS 3320
Query: 838 QDSAMTPPLPLQDTDLSS----APKPVAAATPVSQQAEEGL--TLPQDSAMTAPLPLQDT 891
+ T PLP+ DT +S P PV + + S L T+P ++ L T
Sbjct: 3321 ASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVT 3380
Query: 892 GPTSGPEPLAVATPQTLQAEAGCAPGTE-PVATMAQQEVGEALGPRPAPEEKNAAL-PTV 949
G +S A P T + T PV +++ G+ P P + +A+
Sbjct: 3381 GASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTT-PLPVTDASSASTGQAT 3439
Query: 950 PEP-AALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRP 1008
P P +L V D P DA S A LP + + S
Sbjct: 3440 PLPVTSLSSVSTGDTTPLLVT--------DASSVSTGHATPLP---------VTDTSSAS 3482
Query: 1009 GREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPP 1068
+ T + + + + G PL + G A +P
Sbjct: 3483 TGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDT 3542
Query: 1069 AACPEVSQARLLSPAREERGLS-GKSTPEP-TLPSAVATEASLDSCPESSVGAVSSLDRG 1126
++ RL P + S G++TP P T+PS+ ++ P +S +VS+
Sbjct: 3543 SSASTGDTTRL--PVTDTSSASTGQATPLPVTIPSS-SSSGHTTPLPVTSTSSVSTGHVT 3599
Query: 1127 CPDAPAPTSAPTSQ-QPEPVLGLGSVEQPHEVP 1158
+P+SA T P PV S H P
Sbjct: 3600 PLHVTSPSSASTGHVTPLPVTSTSSASTGHATP 3632
Score = 68.9 bits (167), Expect = 3e-11
Identities = 219/1005 (21%), Positives = 329/1005 (32%), Gaps = 160/1005 (15%)
Query: 382 DDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTV 441
D T +D+ SAS +A + S + V T S G A L D +
Sbjct: 2781 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSS 2840
Query: 442 SWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATR 501
+ A P + S + VT+ A +T+ T ++ G
Sbjct: 2841 ASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTG-------H 2893
Query: 502 VTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDS 561
TP + ++ G A P P + S G + P+ T P +
Sbjct: 2894 ATPLHVTSPSSASTGH-----ATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVT 2948
Query: 562 PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAM----TPPLPLQDTDLSSAP 617
+ G + PV + + V L + S+ T PLP+ DT +S
Sbjct: 2949 DTSSASTGH----ATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTG 3004
Query: 618 KPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSS----APKPVAAATLVSQQAEEG 673
+ A + A G T PLP+ DT +S P PV + + VS
Sbjct: 3005 QATALPVTSTSSASTG--------DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP 3056
Query: 674 L--TLPQDSAMTPPLPLQDTDLSSA------PKPVAAATLVSQQAEEGLTLPQDSAMT-- 723
L T P ++ PL TD SSA P PV + + VS L + S+ +
Sbjct: 3057 LPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTG 3116
Query: 724 --PPLPLQDT------DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS 775
LP+ DT D +S P ++ +T S+ PL T+ SS
Sbjct: 3117 HATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSS 3176
Query: 776 APKPVAAATIVSQQAEEG--------LTLPQDSAM--TPPLPLQDTDLSS----APKPVA 821
A +V+ + +T P ++ T P+P+ DT S P PV
Sbjct: 3177 VSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVT 3236
Query: 822 AATIVSQQAEEGLTLPQDSA----MTPPLPLQDTDLSSA----PKPVAA--------ATP 865
+ S L + S+ PLP+ +T S P PV + ATP
Sbjct: 3237 GLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATP 3296
Query: 866 V----SQQAEEGLTLP--------QDSAMTAPLPLQDT--GPTSGPEPLAVATPQ----- 906
+ + A G P + T PLP+ DT T PL V +P
Sbjct: 3297 LPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTG 3356
Query: 907 -------TLQAEAGCA-PGTEPVATMAQQEVGEALGPRPAPEEKNAALPT---VPEP-AA 954
T+ + A T PV + G A P P +++ T P P +
Sbjct: 3357 HTTPLHVTIPSSASTGDTSTLPVTGASSASTGHA---TPLPVTDTSSVSTGHATPLPVTS 3413
Query: 955 LDQVQQDD--PQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREA 1012
L V D P P +A + Q + L + +LS + +A S A
Sbjct: 3414 LSSVSTGDTTPLPVTDASSASTGQA---TPLPVTSLSSVSTGDTTPLLVTDASSVSTGHA 3470
Query: 1013 CLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACP 1072
T + D+ + + + G PL P ++L D P
Sbjct: 3471 TPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPL-----PVTSLSSV-STGDTTPLLVT 3524
Query: 1073 EVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPA 1132
+ S +G +TP P ++ A+ P + + S+ P
Sbjct: 3525 DASSVS-----------TGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQA----TPL 3569
Query: 1133 PTSAPTSQQ-----PEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGP 1187
P + P+S P PV SV H P + +P ST PL P
Sbjct: 3570 PVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSP----------SSASTGHVTPL-P 3618
Query: 1188 DPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGT 1247
S G A P L A + + S G P V ++A +G
Sbjct: 3619 VTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTP-LPVTDTSSASTGQ 3677
Query: 1248 TQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPS 1292
PL P SLS S + + DA + P V PS
Sbjct: 3678 ATPL---PVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPS 3719
Score = 39.3 bits (90), Expect = 0.029
Identities = 107/505 (21%), Positives = 159/505 (31%), Gaps = 97/505 (19%)
Query: 734 SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 793
++ PK A E G T ++ ++ P + +A P ++ + +++
Sbjct: 553 TTLPKTTGAGAQTQWTQETGTT--GEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQI 610
Query: 794 LTLPQDSAMTPPLPLQDTDLSSAPKPVAAA---TIVSQQAEEGLTLPQDSAMTPPLPLQD 850
T P + T + T S P + T Q +E T S MT
Sbjct: 611 TTAPSTNHST----IHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMT------- 659
Query: 851 TDLSSAPKPVAAATPVSQQAEEGLTLPQD----SAMT--APLPLQDTGPTSGPEPLAVAT 904
D + P ++ T E +PQD SA T AP P D T P A
Sbjct: 660 -DTKTVTTPGSSFTASGHSPSE--IVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAA 716
Query: 905 PQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEK--NAALPTVPEPAAL------- 955
P + A G + GT T A + PE + +A+ T P+ AA
Sbjct: 717 PSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQA 776
Query: 956 ------DQVQQDDPQPA----AEAGTPWAAQEDADSTL--GMEALSL----------PEP 993
Q Q +P + AGT + A T G E +S P
Sbjct: 777 ESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSR 836
Query: 994 ASGAGEEIAEALSRPGREACLEAR----------------AHTGDGAKPDSPQKETLEVE 1037
S + E LS + + +P T
Sbjct: 837 DSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSA 896
Query: 1038 NQQE-GGLKPLAQEHGPRSALGG--------AREVPDAPPAACPEVSQARLLSPAREERG 1088
+ QE + +AQ R++ G A + P P ++ L SP E
Sbjct: 897 SPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHT 956
Query: 1089 L----SGKS------TPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPT 1138
L SGK+ + LP A+ AS V SS+ G P P ++P+
Sbjct: 957 LSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTG-HATPLPVTSPS 1015
Query: 1139 S-----QQPEPVLGLGSVEQPHEVP 1158
S P PV S H P
Sbjct: 1016 SVSTGHTTPLPVTDTSSESTGHVTP 1040
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 76.3 bits (186), Expect = 2e-13
Identities = 128/560 (22%), Positives = 199/560 (35%), Gaps = 73/560 (13%)
Query: 520 AAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGL--DLPSGR 577
AA+ PS EG+ S+ A+ P+P+ E L P EG L DL +
Sbjct: 1870 AAVVTVTPSPEGVFS-----SLQAKPSPSPRAEL---LVPSL------EGALPPDLDTSE 1915
Query: 578 KPVAAATIVPRQAK--EDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLT 635
A A I+P + E L SA+ P++ S + A++++ +E ++
Sbjct: 1916 DQQATAAIIPPEPSYLEPLDEGPFSAVITEEPVEWAHPS---EQALASSLIGGTSENPVS 1972
Query: 636 LPQDSVMTPPLPLQDTEL-----------SSAPKPVAAATLVSQQAEEGLTLPQDSAMTP 684
P S + P + E S+AP P +A+ E P S
Sbjct: 1973 WPVGSDLLLKSPQRFPESPKRFCPADPLHSAAPGPFSAS-------EAPYPAPPASPAPY 2025
Query: 685 PLPLQDT---DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 741
LP+ + D+ V AA S+ A +S + L + L AP+P
Sbjct: 2026 ALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPSGLESFFSNCKSLPEAPLDVAPEPAC 2085
Query: 742 AATLVSQQAE--------EGLTLPQDSAMTPPLPLQDT------DLSSAPKPVAAATIVS 787
A + +A +G P+P D DL P + + +
Sbjct: 2086 VAAVAQVEALGPLENSFLDGSRGLSHLGQVEPVPWADAFAGPEDDLDLGPFSLPELPLQT 2145
Query: 788 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT---- 843
+ A +G P + ++ PP + AP + + + AEE LP D A T
Sbjct: 2146 KDAADGEAEPVEESLAPPEEMPP----GAPGVINGGDVSTVVAEEPPALPPDQASTRLPA 2201
Query: 844 --PPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLA 901
P P + L A + A V ++ G P S AP+P + SG +
Sbjct: 2202 ELEPEPSGEPKLDVALEAAVEAETVPEERARGD--PDSSVEPAPVPPEQRPLGSGDQGAE 2259
Query: 902 VATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQD 961
P A + CAP T+AQ + + GP E AA P P + Q +
Sbjct: 2260 AEGPP---AASLCAPDGPAPNTVAQAQAADGAGPEDDTEASRAAAPAEGPPGGI-QPEAA 2315
Query: 962 DPQPAAEA-GTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHT 1020
+P+P AEA P + T + + G E P +AR
Sbjct: 2316 EPKPTAEAPKAPRVEEIPQRMTRNRAQMLANQSKQGPPPSEKECAPTPAPVTRAKARGSE 2375
Query: 1021 GDGAKPDSPQKETLEVENQQ 1040
D A+ P+K + QQ
Sbjct: 2376 DDDAQAQHPRKRRFQRSTQQ 2395
Score = 60.1 bits (144), Expect = 2e-08
Identities = 164/751 (21%), Positives = 258/751 (34%), Gaps = 106/751 (14%)
Query: 694 SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS-SAPKPVAAATLV----SQ 748
S PK A ++GL +P P +D L S P P AA +
Sbjct: 1615 SGDPKLKEKAKPADDGRKKGLDIPAKKPPGLDPPFKDKKLKESTPIPPAAENKLHPASGA 1674
Query: 749 QAEEGLTLPQDSAMTPPLPLQDTDL-SSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLP 807
+++ L P + P P D + P P + + S EE + P+ TP
Sbjct: 1675 DSKDWLAGPHMKEVLPASPRPDQSRPTGVPTPTSVLSCPSY--EEVMHTPR----TPSCS 1728
Query: 808 LQD--------------TDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL 853
D T + +AP + + + + L ++++ P PL T+L
Sbjct: 1729 ADDYADLVFDCADSQHSTPVPTAPTSACSPSFFDRFSVASSGLSENASQAPARPLS-TNL 1787
Query: 854 SSAPKPVAAATP-----VSQQAEEGLTLPQDSAMTAPLP--LQDTGPTSG--PEPLAVAT 904
+ TP V + ++P S+ +P+P ++D P E A +
Sbjct: 1788 YRSVSVDIRRTPEEEFSVGDKLFRQQSVPAASSYDSPMPPSMEDRAPLPPVPAEKFACLS 1847
Query: 905 PQTLQAEAG----------CAPGTEPVATMAQQEVGEALGPRPAPEEKNAAL-PTVPEPA 953
P + G C P T + + V +L +P+P + L P++
Sbjct: 1848 PGYYSPDYGLPSPKVDALHCPPAAVVTVTPSPEGVFSSLQAKPSPSPRAELLVPSLEGAL 1907
Query: 954 ALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREAC 1013
D +D Q A P + + A+ EP A P +A
Sbjct: 1908 PPDLDTSEDQQATAAIIPPEPSYLEPLDEGPFSAVITEEPVEWA---------HPSEQA- 1957
Query: 1014 LEARAHTGDGAKPDS-PQKETLEVENQQEGGLKP--LAQEHGPRSALGGAREVPDAPPAA 1070
L + G P S P L +++ Q P SA G +AP A
Sbjct: 1958 LASSLIGGTSENPVSWPVGSDLLLKSPQRFPESPKRFCPADPLHSAAPGPFSASEAPYPA 2017
Query: 1071 CPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPD- 1129
P S A P E GL +P+A++T + P S + + S + P+
Sbjct: 2018 -PPASPAPYALPVAEP-GLEDVKDGVDAVPAAISTSEAAPYAPPSGLESFFSNCKSLPEA 2075
Query: 1130 ----APAPTSAPTSQQPEPV-----------LGLGSVEQPHEVPSVLGTPLLQPPENLAK 1174
AP P Q E + GL + Q VP P ++L
Sbjct: 2076 PLDVAPEPACVAAVAQVEALGPLENSFLDGSRGLSHLGQVEPVP--WADAFAGPEDDLDL 2133
Query: 1175 GQPSTPVDRPLGPDPSAPG---TLAGAALPPLE--PPAPCLCQDPQEDSVEDEEPPGSLG 1229
G S P + PL +A G + + PP E P AP + +V EEPP
Sbjct: 2134 GPFSLP-ELPLQTKDAADGEAEPVEESLAPPEEMPPGAPGVINGGDVSTVVAEEPP---A 2189
Query: 1230 LPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVP 1289
LPP QA + A +P G P++ ++ + + + V A+ + P VP
Sbjct: 2190 LPPDQASTRLPAEL---EPEPSGE-PKLDVALEAAVEAETVPEERARGDPDSSVEPAPVP 2245
Query: 1290 PPSGPQSPAGPQGLSAPEQQEDEDSL---EEDSPRALGSGQHSDSHGESSAELDEQDILA 1346
P Q P G A + SL + +P + Q +D G +D
Sbjct: 2246 P---EQRPLGSGDQGAEAEGPPAASLCAPDGPAPNTVAQAQAADGAG-------PEDDTE 2295
Query: 1347 PQTVQCPAQAPAGGSEETIAKAKQSRSEKKA 1377
PA+ P GG + A+ K + KA
Sbjct: 2296 ASRAAAPAEGPPGGIQPEAAEPKPTAEAPKA 2326
Score = 42.4 bits (98), Expect = 0.003
Identities = 88/374 (23%), Positives = 131/374 (35%), Gaps = 55/374 (14%)
Query: 13 PEADRPGPRTD-LSCDAAAATTILGGDRREPCALT--PGPSHLALTFLPSKPGARPQPEG 69
P+ P P+ D L C AA T+ +L P PS A +PS GA P
Sbjct: 1853 PDYGLPSPKVDALHCPPAAVVTVTPSPEGVFSSLQAKPSPSPRAELLVPSLEGALPPDLD 1912
Query: 70 ASWDAGPGGA----PSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEET 125
S D A ++ +P + GP ++ E A +E L ++L +G +
Sbjct: 1913 TSEDQQATAAIIPPEPSYLEPLDEGPFSAVITEEPVEWAHPSEQALASSL-----IGGTS 1967
Query: 126 CQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTY 185
+ P + L+ + P+ P C L +P P S P+ P
Sbjct: 1968 ENPVSWPVGSDLLLKSPQ---RFPESPKRFCPADPLHSAAPGPFSASEAPYPAPPASPAP 2024
Query: 186 ALLPACGPH-GDARDSEAELRDELLDS---PPASPSG---------SYITADGDSWASSP 232
LP P D +D + + S P A PSG S A D A P
Sbjct: 2025 YALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPSGLESFFSNCKSLPEAPLDV-APEP 2083
Query: 233 SC-----SLSLLAPAEGLDFPSGWGLSPQGSM------------VDERELHPAGTPEPPS 275
+C + L P E GLS G + D+ +L P PE P
Sbjct: 2084 ACVAAVAQVEALGPLENSFLDGSRGLSHLGQVEPVPWADAFAGPEDDLDLGPFSLPELP- 2142
Query: 276 SESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEE 335
++ +AD + +E + M P A G + V A E L P++
Sbjct: 2143 LQTKDAADGEAEPVEE------SLAPPEEMPPGAPGVINGGDVSTVVAEEPPALPPDQAS 2196
Query: 336 EE--AVADPDPGGD 347
A +P+P G+
Sbjct: 2197 TRLPAELEPEPSGE 2210
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 75.9 bits (185), Expect = 3e-13
Identities = 161/689 (23%), Positives = 225/689 (32%), Gaps = 126/689 (18%)
Query: 470 EEGLALGQEST-----ATVTPHTLQVAPGLQVEVA--TRVTPQAGEEETDSTAGQE---- 518
++GL + E T AT P ++ G + + + T TP AG E
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 519 -SAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGR 577
A A P+P EG + + S + P+P + GGL P+ R
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR----------RRPSAGGGLQRPASR 240
Query: 578 KPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP 637
++AT + A+ + TP P S PKP + Q +T P
Sbjct: 241 SLSSSATPLSSPARSG----PSARGTPRAPAHP----SQPKPKGLQALRPPQ----VTPP 288
Query: 638 QDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMT----------PPLP 687
+ PL + L++ P +A L SQ P S++T PP P
Sbjct: 289 RKDAAPALGPLSSSPLAT---PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 688 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVS 747
L + P P A QA L P A LP + P P A L
Sbjct: 346 SAPPSLQTLPSPPATPP---SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL-- 400
Query: 748 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATI---VSQQAEEGLTLPQDSAMTP 804
A L P +PPL T AP +A + S + P +P
Sbjct: 401 --ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
Query: 805 PLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 864
P+ T S AP +AA L +P +PP+ T AP P+AA
Sbjct: 459 PVSPSATPPSQAPPSLAAPP---------LQVPPSPPASPPMSPSATPPPQAPPPLAAP- 508
Query: 865 PVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP--QTLQAEAGCAPGTEPVA 922
PL L P + P A+ATP Q L + PG P +
Sbjct: 509 --------------------PLQLAKPPPQAPP---ALATPPLQALPSPPASFPGQAPFS 545
Query: 923 TMAQQEVGEALGPRP-APEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADS 981
A + P P AP A L VP Q +P P + + S
Sbjct: 546 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP------PTPGPDTSVS 599
Query: 982 TLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQE 1041
+ P P + LS P G + S +E ++ E
Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGPDL---------AGHSSSATSTPEELRGYDSGPE 650
Query: 1042 GGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEP--TL 1099
GG A PDA AAC + +R +P RG G P P T
Sbjct: 651 GG--------------AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 696
Query: 1100 PSAVATEASL--DSCPESSVGAVSSLDRG 1126
P + ++ PES+ A +LD G
Sbjct: 697 PGSADGLCTIYETEGPESATPAPGALDPG 725
Score = 72.4 bits (176), Expect = 3e-12
Identities = 129/535 (24%), Positives = 180/535 (33%), Gaps = 93/535 (17%)
Query: 800 SAMTPPLPLQDTDLS-SAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 858
S T P PL L SA + VA L+ + P P P
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-------GTPS 173
Query: 859 PVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT 918
P A + E GL P SA P PT GP + + E A
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRP-------PTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 919 EPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQED 978
P A Q RPA +++ + PA + P+ A P
Sbjct: 227 RPSAGGGLQ--------RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP------ 272
Query: 979 ADSTLGMEALSLPE-------PASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQK 1031
G++AL P+ A G + L+ P A L+++A P +P
Sbjct: 273 --KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP---TLPATPHS 327
Query: 1032 ETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERG--- 1088
+L + L P P + + + +PPA P + L SP +
Sbjct: 328 SSLTCQLATPLPLAP------PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381
Query: 1089 ----LSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTS-----APTS 1139
LS +TP P P A+A + +S L P AP + AP S
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441
Query: 1140 QQPEPVLGLGSVEQPHEVP-----SVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGT 1194
P P V+ P P S TP Q P +LA + P+ P P P A
Sbjct: 442 PPPSP-----PVQAPFSPPASPPVSPSATPPSQAPPSLA----APPLQVP--PSPPASPP 490
Query: 1195 LAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTG 1254
++ +A PP + P P PP L PPPQA A + P +
Sbjct: 491 MSPSATPPPQAPPPLAA------------PPLQLAKPPPQAPPALATPPLQALPSPPASF 538
Query: 1255 P-RVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQ 1308
P + SP + L +A+ + + P QV PPS P SP L AP +
Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV-PPSPPASPT----LQAPRR 588
Score = 71.6 bits (174), Expect = 5e-12
Identities = 148/579 (25%), Positives = 189/579 (32%), Gaps = 82/579 (14%)
Query: 480 TATVTPHTLQVAP-GLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQ 538
T H Q P GLQ +VTP ++ + S+ +A P PS
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPR-KDAAPALGPLSSSPLATPSPSA-------AL 313
Query: 539 ESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQ 598
+S LP +SLT +P L PS + + P QA L P
Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373
Query: 599 DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPK 658
A LP + P P A + A L P +PPL T AP
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPAL----ALPPLQAPPSPPASPPLSPLATPSPQAPN 429
Query: 659 PVAAATL---VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLT 715
+A L S + P +PP+ T S AP +AA L
Sbjct: 430 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL---------Q 480
Query: 716 LPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS 775
+P +PP+ T AP P+AA L Q A+ P A TPPL L S
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPL--QLAKPPPQAPPALA-TPPLQA----LPS 533
Query: 776 APKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLT 835
P S A +LP TPP AP PV AA ++ +
Sbjct: 534 PPASFPGQAPFSPSA----SLPMSPLATPP--------PQAP-PVLAAPLLQVPPSPPAS 580
Query: 836 LPQDSAMTPPLPLQDTDLSS---------APKPVAAATPVSQQAEEGLTLPQDSAMTAPL 886
+ PP P DT +S P P + +P S + L SA + P
Sbjct: 581 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 640
Query: 887 PLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT---EPVATMAQQEVGEALGPRPAPE--- 940
L+ G SGPE A A+P A C P P +A + G P P P
Sbjct: 641 ELR--GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR--GAPGAPLPWPPATG 696
Query: 941 -----------EKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALS 989
E P P ALD P P G A S+ +
Sbjct: 697 PGSADGLCTIYETEGPESATPAPGALD----PGPSPGTSGGKAAAGAGAGASSRSPKQAR 752
Query: 990 LPEPASGA--GEEIAEALSRPGREACLEARAHTGDGAKP 1026
L E GA + LSR A E A G G P
Sbjct: 753 LGELPLGALQASVVQHLLSRTLLLAAAEGAA-GGSGGGP 790
Score = 59.3 bits (142), Expect = 3e-08
Identities = 201/856 (23%), Positives = 278/856 (32%), Gaps = 159/856 (18%)
Query: 600 SAMTPPLPLQDTDLS-SAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPK 658
S T P PL L SA + VA L+ + P P P
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-------GTPS 173
Query: 659 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQ 718
P A + E GL P SA P P + S VS +E T P
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPRKS-----------VSSASEHSTTEPS 221
Query: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778
+A P ++ ++AT +S A G + TP P S PK
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----PSARGTPRAPAHP----SQPK 273
Query: 779 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 838
P + Q +T P+ A PL + L++ P +A + SQ P
Sbjct: 274 PKGLQALRPPQ----VTPPRKDAAPALGPLSSSPLAT---PSPSAALQSQAPPTLPATPH 326
Query: 839 DSAMT----PPLPLQDTDLSSAPK----PVAAATPVSQQAEEGLTLPQDSAMTAPLPLQD 890
S++T PLPL S+ P P ATP SQ A L P A + LP
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ-ATTSLGSPTLQATHSFLPSPP 385
Query: 891 TGPTSGPEPLA---VATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAAL- 946
P + P P A +A P LQA P + P++ +A P+P+ NA
Sbjct: 386 LSPLATPPPQAPPALALPP-LQAPPS-PPASPPLSPLAT----------PSPQAPNALAV 433
Query: 947 -----PTVPEPAALDQVQQDDPQ--PAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGE 999
P P P+ Q P P + + TP A +L L +P P+ A
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP---PSQAPPSLAAPPLQVP-PSPPASP 489
Query: 1000 EIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGG 1059
++ + + P +A A AKP L PL P ++ G
Sbjct: 490 PMSPSATPPP-QAPPPLAAPPLQLAKPPPQAPPALATP--------PLQALPSPPASFPG 540
Query: 1060 AREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA 1119
+ P +P A+ P +S +TP P P +A A L P S
Sbjct: 541 --QAPFSPSASLP----------------MSPLATPPPQAPPVLA--APLLQVPPSPP-- 578
Query: 1120 VSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPST 1179
+S P P PT P + P L L P PS + L P+ +T
Sbjct: 579 -ASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 636
Query: 1180 PVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQP 1239
L S P A A+ PP A C P
Sbjct: 637 STPEELRGYDSGPEGGAAASPPPDAELAAC----------------------------HP 668
Query: 1240 AAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAG 1299
AA + G PL +P +PL P + D C + GP+S
Sbjct: 669 AAWS-RGPAPPLA----FRGAPGAPLPWPPATGPGSAD------GLCTIYETEGPESATP 717
Query: 1300 PQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDE-----------QDILAPQ 1348
G P A G+G + S A L E Q +L+
Sbjct: 718 APGALDPGPSPGTSG----GKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRT 773
Query: 1349 TVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIA 1408
+ A+ AGGS A+ AR A+S L + + + +I V +
Sbjct: 774 LLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTS 833
Query: 1409 -KPDVFKSPASDTYVV 1423
PD SP D VV
Sbjct: 834 FSPDDVASPQGDWTVV 849
Score = 43.5 bits (101), Expect = 0.002
Identities = 72/295 (24%), Positives = 98/295 (33%), Gaps = 25/295 (8%)
Query: 1043 GLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSA 1102
G KPLA+ G +GGA +P++ P A P S SG+ P +
Sbjct: 54 GRKPLAERAG---GIGGAT-IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT 109
Query: 1103 VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLG 1162
P SS G S R P E V + E P S L
Sbjct: 110 -------SPGPVSSPGRASGTTR---PGPLGQKGLRISAEETVARGKATEAPKR--SALS 157
Query: 1163 TPLLQPPENLAKGQPSTPV---DRPLGPDPSAPGTLAGAA-LPPLEPPAPCLCQDPQEDS 1218
+ G PS + R G + P A PP E P + + +
Sbjct: 158 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 217
Query: 1219 VEDEEPPGSLGLPPPQAGVQ-PAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKD 1277
E P + P G+Q PA+ ++S + PL + R S +P S K
Sbjct: 218 TEPS--PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KP 274
Query: 1278 LALQIL-PPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDS 1331
LQ L PP PP GP S +L+ +P L + HS S
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
Score = 38.1 bits (87), Expect = 0.065
Identities = 86/368 (23%), Positives = 120/368 (32%), Gaps = 67/368 (18%)
Query: 27 DAAAATTILGGDRREPCALTPGPSHLALTF----------LPSK-PGARPQP-------- 67
+A + + G RR+ TPG A+ LP P ARP+P
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 68 -EGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETC 126
AS + +P+A P GG LSS A +P + R
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 127 QALLSPRAARTALRDQEGGHASPDPPPEL--CSQGDLSVPSPPPDPDSFFTP--PSTPTK 182
+ P+ + ALR + D P L S L+ PSP S P P+TP
Sbjct: 269 PSQPKPKGLQ-ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHS 327
Query: 183 TTYAL-----LPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGD-------SWAS 230
++ LP P A S + L SPPA+P T+ G S+
Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPSL-----QTLPSPPATPPSQATTSLGSPTLQATHSFLP 382
Query: 231 SPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQ 290
SP S P + P L P + PA P P + S A ++ +
Sbjct: 383 SPPLSPLATPPPQA---PPALALPP----LQAPPSPPASPPLSPLATPSPQAPNALAV-- 433
Query: 291 EGHFFDLDFL--------------ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEE 336
H F A+ P+ P+A P Q ++V P P
Sbjct: 434 --HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491
Query: 337 EAVADPDP 344
A P P
Sbjct: 492 SPSATPPP 499
Score = 34.3 bits (77), Expect = 0.94
Identities = 74/262 (28%), Positives = 90/262 (34%), Gaps = 41/262 (15%)
Query: 31 ATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG--GAPSAWADPGE 88
ATT LG T +H L P P A P P+ A P PS A P
Sbjct: 365 ATTSLGSP-------TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417
Query: 89 GGPSPMLLPEGLSSQALST---EAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGG 145
SP+ P + AL+ +AP P + QA SP A+
Sbjct: 418 ---SPLATPSPQAPNALAVHLLQAPFSPPPSPPV-------QAPFSPPASPPV-----SP 462
Query: 146 HASP--DPPPELCSQGDLSVPSPPPDPD---SFFTPPSTPTKTTYALLPACGPHGDARDS 200
A+P PP L + PSPP P S PP P L P A +
Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522
Query: 201 EAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAP----AEGLDFPSGWGLSPQ 256
A + L SPPAS G + S SP + AP A L P SP
Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP----SPP 578
Query: 257 GSMVDERELHPAGTPEPPSSES 278
S + P TP P +S S
Sbjct: 579 ASPTLQAPRRPP-TPGPDTSVS 599
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 72.0 bits (175), Expect = 4e-12
Identities = 160/615 (26%), Positives = 211/615 (34%), Gaps = 118/615 (19%)
Query: 738 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ--AEE--- 792
K AAA + +A LT + PP P+ L + + AA V ++ AE
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAAL----RVLGAAGAVGRKPLAERAGG 64
Query: 793 --GLTLPQDSAMTPPLPLQDTDLSSAPK--PVAAATIVSQQAEEGLTLPQDSAMTPPLPL 848
G T+P+ + P S + P A T + G + S T P PL
Sbjct: 65 IGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG----RASGTTRPGPL 120
Query: 849 QDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTL 908
L + + A ++ P+ SA++A +GPT G TP
Sbjct: 121 GQKGLRISAEETVARGKATEA-------PKRSALSAGARRDTSGPTPG-------TPSPA 166
Query: 909 QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAE 968
A A GTE VG PRPAP +A P P V E
Sbjct: 167 MARRSRAAGTE---------VGL---PRPAP----SARPRPPTEGPRKSVSSASEHSTTE 210
Query: 969 AGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDS 1028
P A S G L PAS + A LS P R AR A P
Sbjct: 211 ---PSPAARRRPSAGG----GLQRPASRSLSSSATPLSSPARSGP-SARGTPRAPAHPSQ 262
Query: 1029 PQKETLEVEN--QQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSP---- 1082
P+ + L+ Q K A GP S+ A P APP+ S L SP
Sbjct: 263 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATP 322
Query: 1083 ---AREERG---------------LSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLD 1124
A G LS +TP P P A+A + +S L
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382
Query: 1125 RGCPDAPAPTS-----APTSQQPEPVLGLGSVEQPHEVP-----SVLGTPLLQPPENLAK 1174
P AP + AP S P P V+ P P S TP Q P +LA
Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSP-----PVQAPFSPPASPPVSPSATPPSQAPPSLA- 436
Query: 1175 GQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ 1234
+ P+ P P P A ++ +A PP + P P PP L PPPQ
Sbjct: 437 ---APPLQVP--PSPPASPPMSPSATPPPQAPPPLAA------------PPLQLAKPPPQ 479
Query: 1235 AGVQPAAAAVSGTTQPLGTGP-RVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSG 1293
A A + P + P + SP + L +A+ + + P QV PPS
Sbjct: 480 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV-PPSP 538
Query: 1294 PQSPAGPQGLSAPEQ 1308
P SP L AP +
Sbjct: 539 PASPT----LQAPRR 549
Score = 70.5 bits (171), Expect = 1e-11
Identities = 158/679 (23%), Positives = 218/679 (32%), Gaps = 136/679 (20%)
Query: 470 EEGLALGQEST-----ATVTPHTLQVAPGLQVEVA--TRVTPQAGEEETDSTAGQE---- 518
++GL + E T AT P ++ G + + + T TP AG E
Sbjct: 122 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 181
Query: 519 -SAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGR 577
A A P+P EG + + S + P+P + GGL P+ R
Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR----------RRPSAGGGLQRPASR 231
Query: 578 KPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP 637
++AT + A+ + TP P S PKP +GL
Sbjct: 232 SLSSSATPLSSPARSG----PSARGTPRAPAHP----SQPKP------------KGLQAL 271
Query: 638 QDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP 697
+ +TPP AA + + L P SA PP P L + P
Sbjct: 272 RPPQVTPPRK-------------DAAPALGPLSSSPLATPSPSA--PPSPSAPPSLQTLP 316
Query: 698 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLP 757
P A QA L P A LP + P P A L A L P
Sbjct: 317 SPPATPP---SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL----ALPPLQAP 369
Query: 758 QDSAMTPPLPLQDTDLSSAPKPVAAATI---VSQQAEEGLTLPQDSAMTPPLPLQDTDLS 814
+PPL T AP +A + S + P +PP+ T S
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429
Query: 815 SAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGL 874
AP +AA L +P +PP+ T AP P+AA
Sbjct: 430 QAPPSLAAPP---------LQVPPSPPASPPMSPSATPPPQAPPPLAAP----------- 469
Query: 875 TLPQDSAMTAPLPLQDTGPTSGPEPLAVATP--QTLQAEAGCAPGTEPVATMAQQEVGEA 932
PL L P + P A+ATP Q L + PG P + A +
Sbjct: 470 ----------PLQLAKPPPQAPP---ALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516
Query: 933 LGPRP-APEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLP 991
P P AP A L VP Q +P P + + S + P
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP------PTPGPDTSVSGPRLTLALAP 570
Query: 992 EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEH 1051
P + LS P G + S +E ++ EGG
Sbjct: 571 GPPPPPSRSPSSTLSGPDL---------AGHSSSATSTPEELRGYDSGPEGG-------- 613
Query: 1052 GPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEP--TLPSAVATEASL 1109
A PDA AAC + +R +P RG G P P T P + ++
Sbjct: 614 ------AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI 667
Query: 1110 --DSCPESSVGAVSSLDRG 1126
PES+ A +LD G
Sbjct: 668 YETEGPESATPAPGALDPG 686
Score = 68.2 bits (165), Expect = 6e-11
Identities = 141/567 (24%), Positives = 190/567 (33%), Gaps = 86/567 (15%)
Query: 498 VATRVTPQAGEEETDSTAGQESAAMAMP-QPSQEGISEILGQESVTAEKLPTPQEETSLT 556
+++ TP + + +A A A P QP +G+ +++ ++ P+++ +
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL------QALRPPQVTPPRKDAAPA 286
Query: 557 LCPDSPQNLKEEGGLDLPSGRKPVAAATIV------PRQAKEDLTLPQDSAMTPPLPLQD 610
L P S L PS P + T+ P QA L P A LP
Sbjct: 287 LGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346
Query: 611 TDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATL---VS 667
+ P P A + A L P +PPL T AP +A L S
Sbjct: 347 LSPLATPPPQAPPAL----ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402
Query: 668 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 727
+ P +PP+ T S AP +AA L +P +PP+
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL---------QVPPSPPASPPMS 453
Query: 728 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS 787
T AP P+AA L Q A+ P A TPPL L S P S
Sbjct: 454 PSATPPPQAPPPLAAPPL--QLAKPPPQAPPALA-TPPLQA----LPSPPASFPGQAPFS 506
Query: 788 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLP 847
A +LP TPP AP PV AA ++ + + PP P
Sbjct: 507 PSA----SLPMSPLATPP--------PQAP-PVLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Query: 848 LQDTDLSS---------APKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPE 898
DT +S P P + +P S + L SA + P L+ G SGPE
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR--GYDSGPE 611
Query: 899 PLAVATPQTLQAEAGCAPGT---EPVATMAQQEVGEALGPRPAPE--------------E 941
A A+P A C P P +A + G P P P E
Sbjct: 612 GGAAASPPPDAELAACHPAAWSRGPAPPLAFR--GAPGAPLPWPPATGPGSADGLCTIYE 669
Query: 942 KNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGA--GE 999
P P ALD P P G A S+ + L E GA
Sbjct: 670 TEGPESATPAPGALD----PGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQAS 725
Query: 1000 EIAEALSRPGREACLEARAHTGDGAKP 1026
+ LSR A E A G G P
Sbjct: 726 VVQHLLSRTLLLAAAEGAA-GGSGGGP 751
Score = 54.3 bits (129), Expect = 9e-07
Identities = 194/816 (23%), Positives = 264/816 (32%), Gaps = 155/816 (18%)
Query: 643 TPPLPLQDTELS-SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 701
T P PL L SA + VA L+ + P P P P
Sbjct: 115 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-------GTPSPAM 167
Query: 702 AATLVSQQAEEGLTLPQDSAMT-PPLPLQDTDLSSA-------PKPVAAATLVSQQAEEG 753
A + E GL P SA PP +SSA P P A A G
Sbjct: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR---PSAGGG 224
Query: 754 LTLPQD---SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQD 810
L P S+ PL SA A SQ +GL + +TPP
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK--- 281
Query: 811 TDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQA 870
D + A P++++ + + P SA PP P L + P P ATP SQ A
Sbjct: 282 -DAAPALGPLSSSPLAT---------PSPSA--PPSPSAPPSLQTLPSP--PATPPSQ-A 326
Query: 871 EEGLTLPQDSAMTAPLPLQDTGPTSGPEPLA---VATPQTLQAEAGCAPGTEPVATMAQQ 927
L P A + LP P + P P A +A P LQA P + P++ +A
Sbjct: 327 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP-LQAPPS-PPASPPLSPLAT- 383
Query: 928 EVGEALGPRPAPEEKNAAL------PTVPEPAALDQVQQDDPQ--PAAEAGTPWAAQEDA 979
P+P+ NA P P P+ Q P P + + TP A
Sbjct: 384 ---------PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP---PSQA 431
Query: 980 DSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQ 1039
+L L +P P+ A ++ + + P +A A AKP L
Sbjct: 432 PPSLAAPPLQVP-PSPPASPPMSPSATPPP-QAPPPLAAPPLQLAKPPPQAPPALATP-- 487
Query: 1040 QEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTL 1099
PL P ++ G + P +P A+ P +S +TP P
Sbjct: 488 ------PLQALPSPPASFPG--QAPFSPSASLP----------------MSPLATPPPQA 523
Query: 1100 PSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPS 1159
P +A A L P S +S P P PT P + P L L P PS
Sbjct: 524 PPVLA--APLLQVPPSPP---ASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPPPPPS 577
Query: 1160 VLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSV 1219
+ L P+ +T L S P A A+ PP A C
Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC---------- 627
Query: 1220 EDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLA 1279
PAA + G PL +P +PL P + D
Sbjct: 628 ------------------HPAAWS-RGPAPPLA----FRGAPGAPLPWPPATGPGSAD-- 662
Query: 1280 LQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAEL 1339
C + GP+S G P A G+G + S A L
Sbjct: 663 ----GLCTIYETEGPESATPAPGALDPGPSPGTSG----GKAAAGAGAGASSRSPKQARL 714
Query: 1340 DE-----------QDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQ 1388
E Q +L+ + A+ AGGS A+ AR A+S L +
Sbjct: 715 GELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGR 774
Query: 1389 IQGVTRITIQKSKNILFVIA-KPDVFKSPASDTYVV 1423
+ + +I V + PD SP D VV
Sbjct: 775 WAELLSPLDESRASITSVTSFSPDDVASPQGDWTVV 810
Score = 38.1 bits (87), Expect = 0.065
Identities = 76/342 (22%), Positives = 108/342 (31%), Gaps = 45/342 (13%)
Query: 27 DAAAATTILGGDRREPCALTPGPSHLALTF----------LPSK-PGARPQP-------- 67
+A + + G RR+ TPG A+ LP P ARP+P
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199
Query: 68 -EGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETC 126
AS + +P+A P GG LSS A +P + R
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 259
Query: 127 QALLSPRAARTALRDQEGGHASPDPPPEL--CSQGDLSVPSP--PPDPDSFFTPPSTPTK 182
+ P+ + ALR + D P L S L+ PSP PP P + PPS T
Sbjct: 260 PSQPKPKGLQ-ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA---PPSLQTL 315
Query: 183 TTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPA 242
+ P + L SPP SP + + A P + P+
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA----PPS 371
Query: 243 EGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLAN 302
P +P + +H P P + A S A+
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP-------------AS 418
Query: 303 DPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDP 344
P+ P+A P Q ++V P P A P P
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Score = 38.1 bits (87), Expect = 0.065
Identities = 51/212 (24%), Positives = 75/212 (35%), Gaps = 32/212 (15%)
Query: 13 PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72
P GPR +S + +TT P P A PS G +P S
Sbjct: 189 PRPPTEGPRKSVSSASEHSTT------------EPSP---AARRRPSAGGGLQRPASRSL 233
Query: 73 DAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSP 132
+ + + + P GPS P + + L A P++ + L P
Sbjct: 234 SS----SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 289
Query: 133 RAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPP-STPT-KTTYALLPA 190
++ SP PP L ++PSPP P S T +PT + T++ LP+
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSL-----QTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 191 ------CGPHGDARDSEAELRDELLDSPPASP 216
P A + A + SPPASP
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASP 376
Score = 34.3 bits (77), Expect = 0.94
Identities = 74/262 (28%), Positives = 90/262 (34%), Gaps = 41/262 (15%)
Query: 31 ATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG--GAPSAWADPGE 88
ATT LG T +H L P P A P P+ A P PS A P
Sbjct: 326 ATTSLGSP-------TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378
Query: 89 GGPSPMLLPEGLSSQALST---EAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGG 145
SP+ P + AL+ +AP P + QA SP A+
Sbjct: 379 ---SPLATPSPQAPNALAVHLLQAPFSPPPSPPV-------QAPFSPPASPPV-----SP 423
Query: 146 HASP--DPPPELCSQGDLSVPSPPPDPD---SFFTPPSTPTKTTYALLPACGPHGDARDS 200
A+P PP L + PSPP P S PP P L P A +
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 483
Query: 201 EAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAP----AEGLDFPSGWGLSPQ 256
A + L SPPAS G + S SP + AP A L P SP
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP----SPP 539
Query: 257 GSMVDERELHPAGTPEPPSSES 278
S + P TP P +S S
Sbjct: 540 ASPTLQAPRRPP-TPGPDTSVS 560
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,094,302
Number of Sequences: 37866
Number of extensions: 5114355
Number of successful extensions: 37660
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 1742
Number of HSP's that attempted gapping in prelim test: 21451
Number of HSP's gapped (non-prelim): 13159
length of query: 1522
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1407
effective length of database: 13,892,928
effective search space: 19547349696
effective search space used: 19547349696
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.