BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|238814389 zinc finger, MYND domain containing 11 isoform a [Homo sapiens] (602 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|238814389 zinc finger, MYND domain containing 11 isoform a [H... 1263 0.0 gi|238814385 zinc finger, MYND domain containing 11 isoform a [H... 1263 0.0 gi|238814387 zinc finger, MYND domain containing 11 isoform b [H... 1159 0.0 gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 186 5e-47 gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 186 5e-47 gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 186 7e-47 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 5e-07 gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 53 7e-07 gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 53 7e-07 gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 53 7e-07 gi|74027251 tripartite motif-containing 33 protein isoform beta ... 52 1e-06 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 51 3e-06 gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 49 1e-05 gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo... 49 1e-05 gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 49 1e-05 gi|21071070 transmembrane channel-like 1 [Homo sapiens] 49 2e-05 gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 49 2e-05 gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 48 3e-05 gi|115648142 centrosomal protein 164kDa [Homo sapiens] 47 5e-05 gi|148746195 trichohyalin [Homo sapiens] 46 9e-05 gi|74027249 tripartite motif-containing 33 protein isoform alpha... 45 1e-04 gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens] 45 2e-04 gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 44 3e-04 gi|58530840 desmoplakin isoform I [Homo sapiens] 44 4e-04 gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] 44 4e-04 gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 44 6e-04 gi|92859701 myosin VI [Homo sapiens] 43 7e-04 gi|153945728 microtubule-associated protein 1B [Homo sapiens] 43 7e-04 gi|28329422 acute myelogenous leukemia 1 translocation 1 protein... 43 0.001 gi|28329419 acute myelogenous leukemia 1 translocation 1 protein... 43 0.001 >gi|238814389 zinc finger, MYND domain containing 11 isoform a [Homo sapiens] Length = 602 Score = 1263 bits (3269), Expect = 0.0 Identities = 602/602 (100%), Positives = 602/602 (100%) Query: 1 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV 60 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV Sbjct: 1 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV 60 Query: 61 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR 120 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR Sbjct: 61 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR 120 Query: 121 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG 180 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG Sbjct: 121 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG 180 Query: 181 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADI 240 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADI Sbjct: 181 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADI 240 Query: 241 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ 300 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ Sbjct: 241 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ 300 Query: 301 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG 360 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG Sbjct: 301 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG 360 Query: 361 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS 420 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS Sbjct: 361 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS 420 Query: 421 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD 480 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD Sbjct: 421 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD 480 Query: 481 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV 540 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV Sbjct: 481 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV 540 Query: 541 EEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRR 600 EEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRR Sbjct: 541 EEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRR 600 Query: 601 KR 602 KR Sbjct: 601 KR 602 >gi|238814385 zinc finger, MYND domain containing 11 isoform a [Homo sapiens] Length = 602 Score = 1263 bits (3269), Expect = 0.0 Identities = 602/602 (100%), Positives = 602/602 (100%) Query: 1 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV 60 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV Sbjct: 1 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV 60 Query: 61 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR 120 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR Sbjct: 61 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR 120 Query: 121 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG 180 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG Sbjct: 121 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG 180 Query: 181 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADI 240 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADI Sbjct: 181 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADI 240 Query: 241 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ 300 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ Sbjct: 241 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ 300 Query: 301 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG 360 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG Sbjct: 301 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG 360 Query: 361 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS 420 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS Sbjct: 361 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS 420 Query: 421 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD 480 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD Sbjct: 421 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD 480 Query: 481 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV 540 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV Sbjct: 481 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV 540 Query: 541 EEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRR 600 EEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRR Sbjct: 541 EEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRR 600 Query: 601 KR 602 KR Sbjct: 601 KR 602 >gi|238814387 zinc finger, MYND domain containing 11 isoform b [Homo sapiens] Length = 567 Score = 1159 bits (2998), Expect = 0.0 Identities = 561/562 (99%), Positives = 561/562 (99%), Gaps = 1/562 (0%) Query: 1 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV 60 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV Sbjct: 1 MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAV 60 Query: 61 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR 120 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR Sbjct: 61 KDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFR 120 Query: 121 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG 180 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG Sbjct: 121 VYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKG 180 Query: 181 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADI 240 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYG DSEQADI Sbjct: 181 KDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYG-DSEQADI 239 Query: 241 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ 300 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ Sbjct: 240 ARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQ 299 Query: 301 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG 360 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG Sbjct: 300 KEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREG 359 Query: 361 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS 420 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS Sbjct: 360 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS 419 Query: 421 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD 480 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD Sbjct: 420 SQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKD 479 Query: 481 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV 540 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV Sbjct: 480 RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFV 539 Query: 541 EEIKKLATQHKQLISQTKKKQW 562 EEIKKLATQHKQLISQTKKKQW Sbjct: 540 EEIKKLATQHKQLISQTKKKQW 561 >gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo sapiens] Length = 1188 Score = 186 bits (472), Expect = 5e-47 Identities = 100/286 (34%), Positives = 154/286 (53%), Gaps = 23/286 (8%) Query: 88 PGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPV 144 P D + + N D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP Sbjct: 97 PVDVVPQDGRN-DFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPE 149 Query: 145 CRSIKKKNTNK-----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLV 192 C I + +++ L+F + +MK+ D +K +HP Y + Sbjct: 150 CEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYI 209 Query: 193 HSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHEL 252 +D+ T+++ + Y E F ADA+ +LHN +I+ G + + IA+++ K HE+ Sbjct: 210 FHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEM 269 Query: 253 DELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFG 312 +E+++C C+ + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG Sbjct: 270 NEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG 329 Query: 313 HHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358 H RAW+P N ++ I K + A E+E++ +R Sbjct: 330 -QHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 374 Score = 95.9 bits (237), Expect = 9e-20 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%) Query: 401 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460 + +V+ K+ P T ++ + P S+ST ++A P + + Sbjct: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900 Query: 461 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513 S D T+I+ND K T + E + +LR E+E+ + +Q + Sbjct: 901 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 952 Query: 514 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572 ++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQWC NC++EA++ Sbjct: 953 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 1011 Query: 573 HCCWNTSYCSIKCQQEHWHAEHKRTC 598 +CCWNTSYC CQQ HW EH ++C Sbjct: 1012 YCCWNTSYCDYPCQQAHW-PEHMKSC 1036 >gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo sapiens] Length = 1160 Score = 186 bits (472), Expect = 5e-47 Identities = 100/286 (34%), Positives = 154/286 (53%), Gaps = 23/286 (8%) Query: 88 PGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPV 144 P D + + N D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP Sbjct: 97 PVDVVPQDGRN-DFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPE 149 Query: 145 CRSIKKKNTNK-----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLV 192 C I + +++ L+F + +MK+ D +K +HP Y + Sbjct: 150 CEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYI 209 Query: 193 HSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHEL 252 +D+ T+++ + Y E F ADA+ +LHN +I+ G + + IA+++ K HE+ Sbjct: 210 FHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEM 269 Query: 253 DELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFG 312 +E+++C C+ + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG Sbjct: 270 NEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG 329 Query: 313 HHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358 H RAW+P N ++ I K + A E+E++ +R Sbjct: 330 -QHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 374 Score = 95.9 bits (237), Expect = 9e-20 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%) Query: 401 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460 + +V+ K+ P T ++ + P S+ST ++A P + + Sbjct: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900 Query: 461 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513 S D T+I+ND K T + E + +LR E+E+ + +Q + Sbjct: 901 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 952 Query: 514 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572 ++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQWC NC++EA++ Sbjct: 953 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 1011 Query: 573 HCCWNTSYCSIKCQQEHWHAEHKRTC 598 +CCWNTSYC CQQ HW EH ++C Sbjct: 1012 YCCWNTSYCDYPCQQAHW-PEHMKSC 1036 >gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo sapiens] Length = 1135 Score = 186 bits (471), Expect = 7e-47 Identities = 97/275 (35%), Positives = 150/275 (54%), Gaps = 22/275 (8%) Query: 99 HDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPVCRSIKKKNTNK 155 +D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP C I + Sbjct: 82 NDFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPECEKITVAECIE 135 Query: 156 -----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLVHSAVDVPTIQE 203 +++ L+F + +MK+ D +K +HP Y + +D+ T+++ Sbjct: 136 TQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEK 195 Query: 204 KVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFY 263 + Y E F ADA+ +LHN +I+ G + + IA+++ K HE++E+++C C+ Sbjct: 196 NAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYL 255 Query: 264 LSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSE 323 + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG H RAW+P Sbjct: 256 AACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG-QHDRAWVPIN 314 Query: 324 NIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358 N ++ I K + A E+E++ +R Sbjct: 315 NCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 349 Score = 95.9 bits (237), Expect = 9e-20 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%) Query: 401 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460 + +V+ K+ P T ++ + P S+ST ++A P + + Sbjct: 816 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875 Query: 461 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513 S D T+I+ND K T + E + +LR E+E+ + +Q + Sbjct: 876 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 927 Query: 514 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572 ++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQWC NC++EA++ Sbjct: 928 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 986 Query: 573 HCCWNTSYCSIKCQQEHWHAEHKRTC 598 +CCWNTSYC CQQ HW EH ++C Sbjct: 987 YCCWNTSYCDYPCQQAHW-PEHMKSC 1011 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 53.5 bits (127), Expect = 5e-07 Identities = 67/340 (19%), Positives = 137/340 (40%), Gaps = 62/340 (18%) Query: 282 ELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSM 341 E++W K + + +KE+ + + W E I+++ +H R Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRLE------EMMWEKEEKIRELEEKMHEQEKIREQ 395 Query: 342 GWKKACDEL--ELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGR 399 K+ +E E +R +E + W+ + + R +EE I + + ++ ++ Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE---KIREQEKKMWRQEEKIHEQEKI 452 Query: 400 RNQSVEPKKEEPEPETEAVSSSQEIPTMPQPI-EKVSVSTQTKKLSASSPRMLHRSTQTT 458 R + ++EE + E + +EI + + E+ + Q +K+ +M Sbjct: 453 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM-------- 504 Query: 459 NDGVCQSMCHDKYTKIFNDFKDRMKSDHK-RETERVVREALEKLRS--EMEEEKRQAVNK 515 HD+ KI + + + K RE E +RE EK+R EM +E+ + + + Sbjct: 505 ---------HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555 Query: 516 AVANMQG------------EMDRKCKQVKEKCK--EEFVEEIKKLATQHKQLISQTKKKQ 561 MQ E + K ++ KEK + EE + E ++ + ++++ + ++K Sbjct: 556 QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615 Query: 562 WCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRK 601 W +EE M C+QE E + RR+ Sbjct: 616 W---EQEEKM-------------CEQEEKMQEQEEKMRRQ 639 Score = 38.5 bits (88), Expect = 0.018 Identities = 43/214 (20%), Positives = 96/214 (44%), Gaps = 19/214 (8%) Query: 361 RFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSS 420 R+ + ++R E ++ ++E+LK E AK + Q VE +K E + + + Sbjct: 193 RYIEELTKERDALSLELYRNTITDEELK---EKNAKLQEKLQLVESEKSEIQLNVKELKR 249 Query: 421 SQEIPTMPQPIEKVSVSTQT--KKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDF 478 E + P +++ K+L + S ++ Q + + + + K++ Sbjct: 250 KLERAKLLLPQQQLQAEADHLGKELQSVSAKL---QAQVEENELWNRLNQQQEEKMWRQE 306 Query: 479 KDRMKSDHK-RETERVVREALEKLRSEMEEEKRQ--------AVNKAVANMQGEMDRKCK 529 + + + K +E E +RE EK+R + E+ +RQ + M E + K + Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366 Query: 530 QVKEKC--KEEFVEEIKKLATQHKQLISQTKKKQ 561 +++E KEE + E+++ + +++ Q +K+Q Sbjct: 367 RLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 400 >gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1 [Homo sapiens] Length = 2000 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 9/102 (8%) Query: 90 DEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVCRSIK 149 +E+D +H YC C GE+++CD C R YH CL E R W CP C Sbjct: 369 EEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELD-RAPEGKWSCPHCEKEG 427 Query: 150 KKNTNKQEMGTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRL 191 + K+E Y +E + +K +++ H Y R+ Sbjct: 428 VQWEAKEEEEEY--------EEEGEEEGEKEEEDDHMEYCRV 461 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Query: 81 EQEGYWLPGDEIDW--ETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRD-SS 137 E+E Y G+E E ++H YC C GE+L CD C YH CL+ L D + Sbjct: 435 EEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP--LPDIPN 492 Query: 138 SPWQCPVC 145 W CP C Sbjct: 493 GEWLCPRC 500 >gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2 [Homo sapiens] Length = 1966 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 9/102 (8%) Query: 90 DEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVCRSIK 149 +E+D +H YC C GE+++CD C R YH CL E R W CP C Sbjct: 369 EEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELD-RAPEGKWSCPHCEKEG 427 Query: 150 KKNTNKQEMGTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRL 191 + K+E Y +E + +K +++ H Y R+ Sbjct: 428 VQWEAKEEEEEY--------EEEGEEEGEKEEEDDHMEYCRV 461 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Query: 81 EQEGYWLPGDEIDW--ETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRD-SS 137 E+E Y G+E E ++H YC C GE+L CD C YH CL+ L D + Sbjct: 435 EEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP--LPDIPN 492 Query: 138 SPWQCPVC 145 W CP C Sbjct: 493 GEWLCPRC 500 >gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3 [Homo sapiens] Length = 2059 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 9/102 (8%) Query: 90 DEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVCRSIK 149 +E+D +H YC C GE+++CD C R YH CL E R W CP C Sbjct: 428 EEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELD-RAPEGKWSCPHCEKEG 486 Query: 150 KKNTNKQEMGTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRL 191 + K+E Y +E + +K +++ H Y R+ Sbjct: 487 VQWEAKEEEEEY--------EEEGEEEGEKEEEDDHMEYCRV 520 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Query: 81 EQEGYWLPGDEIDW--ETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRD-SS 137 E+E Y G+E E ++H YC C GE+L CD C YH CL+ L D + Sbjct: 494 EEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP--LPDIPN 551 Query: 138 SPWQCPVC 145 W CP C Sbjct: 552 GEWLCPRC 559 >gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo sapiens] Length = 1110 Score = 52.4 bits (124), Expect = 1e-06 Identities = 43/167 (25%), Positives = 75/167 (44%), Gaps = 24/167 (14%) Query: 98 NHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVCRSIKK------- 150 N DW C C G++L C+ C +V+H C L S W C CR I K Sbjct: 886 NEDW-CAVCQNGGDLLCCEKCPKVFHLTCHVPTL-LSFPSGDWICTFCRDIGKPEVEYDC 943 Query: 151 ---KNTNKQEMGTYLRFIVSRMKERAI------DLNKKGKD---NKHPMYRRLVHSAVDV 198 +++ K + L + R ER + +L+ + ++ P Y +++ +D+ Sbjct: 944 DNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDL 1003 Query: 199 PTIQEKVNEGKYRSY---EEFKADAQLLLHNTVIFYGADSEQADIAR 242 T+++K+ + + Y ++F AD +L+ N F ADSE A + Sbjct: 1004 STVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGK 1050 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 51.2 bits (121), Expect = 3e-06 Identities = 53/247 (21%), Positives = 107/247 (43%), Gaps = 22/247 (8%) Query: 319 WIPSENIQDITVNIHRLHVKRSMGWKKACDEL--ELHQRFLREGRFWKSKNEDRGEEEAE 376 W E I+++ +H R K+ +E E +R +E + W+ + + R +EE Sbjct: 340 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK- 398 Query: 377 SSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSV 436 EQ ++ QE K G + + + ++EE + + E + +E ++ + Sbjct: 399 ------IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE----QEKKI 448 Query: 437 STQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVRE 496 Q +K+ M + + MC + + K R + + RE E+ +RE Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQE--GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506 Query: 497 ALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVK--EKCKEEFVEEIKKLATQHKQLI 554 EK+R E EE ++ K M + ++ C+Q + ++ +E+ + +K+ Q +L Sbjct: 507 QEEKIR-EQEEMMQEQEEK----MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLR 561 Query: 555 SQTKKKQ 561 Q +K Q Sbjct: 562 QQEEKMQ 568 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/175 (17%), Positives = 77/175 (44%), Gaps = 34/175 (19%) Query: 388 KVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASS 447 ++ Q+ K R+ + ++ ++E+ + + E + +E K+ Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE------------------KMRRQE 322 Query: 448 PRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEE 507 M + + + M +K KI + +++M K + R+ EK+R E+ Sbjct: 323 EMMWEKEEKMRRQ---EEMMWEKEEKI-RELEEKMHEQEKIREQEEKRQEEEKIR---EQ 375 Query: 508 EKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQW 562 EKRQ + +M R+ ++++E+ EE + E +++ + ++ + + ++K W Sbjct: 376 EKRQ-------EQEAKMWRQEEKIREQ--EEKIREQEEMMQEQEEKMGEQEEKMW 421 >gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo sapiens] Length = 530 Score = 49.3 bits (116), Expect = 1e-05 Identities = 66/312 (21%), Positives = 137/312 (43%), Gaps = 34/312 (10%) Query: 282 ELVWAKMKGFGFWPAKVMQKED-------NQVDVRFFGHHHQRAWIPSENIQDITVNIHR 334 +L++AKMKG+ WPA+V + D N++ + FFG H+ A++ ++I + N + Sbjct: 9 DLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFG-THETAFLGPKDIFPYSENKEK 67 Query: 335 L-HVKRSMGWKKACDELELHQ--RFLREGRFWKSKN--EDRGEEEAESSIS--------S 381 + G+ + E++ + +F + K N D EE E+S+S Sbjct: 68 YGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEK 127 Query: 382 TSNEQ----LKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVS 437 SNE + +T A++GR+ ++ + + E ++S + P+ + Sbjct: 128 ASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATE 187 Query: 438 TQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDH--KRETERVVR 495 + K P+M+ + + +D + + K + K + K D ++E ++ + Sbjct: 188 VKIPK-PRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRK 246 Query: 496 EALEKLRSEMEEEKRQAVNK----AVANMQGEMDRKCKQVKEKCKEEFVEEIKK--LATQ 549 E +K + E KR+ + K + ++ + E D + + K K F ++ L Q Sbjct: 247 EPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQ 306 Query: 550 HKQLISQTKKKQ 561 H++ + K+KQ Sbjct: 307 HEKEAADRKRKQ 318 >gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo sapiens] Length = 333 Score = 49.3 bits (116), Expect = 1e-05 Identities = 66/312 (21%), Positives = 137/312 (43%), Gaps = 34/312 (10%) Query: 282 ELVWAKMKGFGFWPAKVMQKED-------NQVDVRFFGHHHQRAWIPSENIQDITVNIHR 334 +L++AKMKG+ WPA+V + D N++ + FFG H+ A++ ++I + N + Sbjct: 9 DLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFG-THETAFLGPKDIFPYSENKEK 67 Query: 335 L-HVKRSMGWKKACDELELHQ--RFLREGRFWKSKN--EDRGEEEAESSIS--------S 381 + G+ + E++ + +F + K N D EE E+S+S Sbjct: 68 YGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEK 127 Query: 382 TSNEQ----LKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVS 437 SNE + +T A++GR+ ++ + + E ++S + P+ + Sbjct: 128 ASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATE 187 Query: 438 TQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDH--KRETERVVR 495 + K P+M+ + + +D + + K + K + K D ++E ++ + Sbjct: 188 VKIPK-PRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRK 246 Query: 496 EALEKLRSEMEEEKRQAVNK----AVANMQGEMDRKCKQVKEKCKEEFVEEIKK--LATQ 549 E +K + E KR+ + K + ++ + E D + + K K F ++ L Q Sbjct: 247 EPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQ 306 Query: 550 HKQLISQTKKKQ 561 H++ + K+KQ Sbjct: 307 HEKEAADRKRKQ 318 >gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo sapiens] Length = 530 Score = 49.3 bits (116), Expect = 1e-05 Identities = 66/312 (21%), Positives = 137/312 (43%), Gaps = 34/312 (10%) Query: 282 ELVWAKMKGFGFWPAKVMQKED-------NQVDVRFFGHHHQRAWIPSENIQDITVNIHR 334 +L++AKMKG+ WPA+V + D N++ + FFG H+ A++ ++I + N + Sbjct: 9 DLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFG-THETAFLGPKDIFPYSENKEK 67 Query: 335 L-HVKRSMGWKKACDELELHQ--RFLREGRFWKSKN--EDRGEEEAESSIS--------S 381 + G+ + E++ + +F + K N D EE E+S+S Sbjct: 68 YGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEK 127 Query: 382 TSNEQ----LKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVS 437 SNE + +T A++GR+ ++ + + E ++S + P+ + Sbjct: 128 ASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATE 187 Query: 438 TQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDH--KRETERVVR 495 + K P+M+ + + +D + + K + K + K D ++E ++ + Sbjct: 188 VKIPK-PRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRK 246 Query: 496 EALEKLRSEMEEEKRQAVNK----AVANMQGEMDRKCKQVKEKCKEEFVEEIKK--LATQ 549 E +K + E KR+ + K + ++ + E D + + K K F ++ L Q Sbjct: 247 EPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQ 306 Query: 550 HKQLISQTKKKQ 561 H++ + K+KQ Sbjct: 307 HEKEAADRKRKQ 318 >gi|21071070 transmembrane channel-like 1 [Homo sapiens] Length = 760 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 22/161 (13%) Query: 402 QSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDG 461 + V+ K EE E ETE SS +E + + S+ + K R+ N+ Sbjct: 4 KKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRK-----------RTRDVINED 52 Query: 462 VCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQ 521 + D+ T+ + + R + E E + E LE+L++E++E KRQ + Sbjct: 53 DPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDE-KRQIIATV----- 106 Query: 522 GEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQW 562 KCK K + K E ++E KK ++++ + + K K+W Sbjct: 107 -----KCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKRW 142 >gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sapiens] Length = 1954 Score = 48.5 bits (114), Expect = 2e-05 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 94 WETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVC 145 +ET++ D YC C GE+++CD C R YH CL E + W CP C Sbjct: 338 YETDHQD-YCEVCQQGGEIILCDTCPRAYHLVCLDPELE-KAPEGKWSCPHC 387 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 10/74 (13%) Query: 81 EQEGY-WLPGDEIDWETE--------NHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEF 131 E+EG W P D+ D E E +H +C C GE+L CD C YH CL+ Sbjct: 388 EKEGIQWEPKDDDDEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPL 447 Query: 132 RLRDSSSPWQCPVC 145 + W CP C Sbjct: 448 P-EIPNGEWLCPRC 460 >gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sapiens] Length = 1912 Score = 47.8 bits (112), Expect = 3e-05 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 94 WETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVC 145 +ET++ D YC C GE+++CD C R YH CL + + W CP C Sbjct: 365 YETDHQD-YCEVCQQGGEIILCDTCPRAYHMVCLDPDME-KAPEGKWSCPHC 414 Score = 40.8 bits (94), Expect = 0.004 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 89 GDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVC 145 G +++ E ++H +C C GE+L CD C YH CL+ + W CP C Sbjct: 438 GGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLP-EIPNGEWLCPRC 493 >gi|115648142 centrosomal protein 164kDa [Homo sapiens] Length = 1460 Score = 47.0 bits (110), Expect = 5e-05 Identities = 55/283 (19%), Positives = 121/283 (42%), Gaps = 28/283 (9%) Query: 299 MQKEDNQVDVRFFGHHHQR-AWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFL 357 +QK + + R QR +W+ ++ + ++ ++ +K +ELE Q+ Sbjct: 651 LQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAE 710 Query: 358 REGRFWKS-------KNEDRGEEEAESSISSTSNEQLKVTQEPRAK-KGRRNQSVEPKKE 409 R K+ K E E++E + + + E K Q+ R + +G R ++V ++ Sbjct: 711 RASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKE--KALQQLREQLEGERKEAVATLEK 768 Query: 410 EPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPR---MLHRSTQTTNDGVCQSM 466 E E E + SS E + VS+ KK+ + + L + V Q Sbjct: 769 EHSAELERLCSSLEAK------HREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKS 822 Query: 467 CH-----DKYTKIFNDFKDRMKSDHKRETERVVRE---ALEKLRSEMEEEKRQAVNKAVA 518 H + + + + + ++ +H+R +++ E + K R + E E+R+ + + Sbjct: 823 YHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLG 882 Query: 519 NMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQ 561 ++ GE++R + + + + E+ K+L ++ Q +K Q Sbjct: 883 HLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQ 925 Score = 38.5 bits (88), Expect = 0.018 Identities = 47/233 (20%), Positives = 94/233 (40%), Gaps = 32/233 (13%) Query: 350 LELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKE 409 LE QR L E + +++ ++ E E L++ Q+ K + S+ + + Sbjct: 603 LEQDQRHLLESK------QEKMQQLREKLCQEEEEEILRLHQQ----KEQSLSSLRERLQ 652 Query: 410 EPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKK--LSASSPRMLH--RSTQTTNDGVCQS 465 + E EA +E + +V STQ + + A L R + ++ Sbjct: 653 KAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERA 712 Query: 466 MCHDKYTKIFNDFKDRMKSDHKRETERV---VREALEKLRSEMEEEKRQAVNKAVANMQG 522 K ++ K+ +++ K E + +AL++LR ++E E+++AV Sbjct: 713 SLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSA 772 Query: 523 EMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCC 575 E++R C ++ K H++++S +KK +EEA C Sbjct: 773 ELERLCSSLEAK---------------HREVVSSLQKKIQEAQQKEEAQLQKC 810 Score = 36.6 bits (83), Expect = 0.068 Identities = 48/206 (23%), Positives = 82/206 (39%), Gaps = 8/206 (3%) Query: 372 EEEAESSISSTSNEQLK--VTQEPRAKKGRRNQSVE---PKKEEPEPETEAVSSSQEIPT 426 ++E +S S E+L + E RA+ R+ + E P+ E +PE + E Sbjct: 456 QDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSA 515 Query: 427 MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDH 486 ++ Q A+ + + +Q G Q D K+ + S Sbjct: 516 ASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPV-SPE 574 Query: 487 KRETERVV--REALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIK 544 R TE V + E MEE Q + + ++ K +Q++EK +E EEI Sbjct: 575 VRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEIL 634 Query: 545 KLATQHKQLISQTKKKQWCYNCEEEA 570 +L Q +Q +S +++ EEEA Sbjct: 635 RLHQQKEQSLSSLRERLQKAIEEEEA 660 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 46.2 bits (108), Expect = 9e-05 Identities = 44/225 (19%), Positives = 105/225 (46%), Gaps = 12/225 (5%) Query: 343 WKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQ 402 W K +E E H++ R+ + + + E+R E + +Q + Q+ R ++ R + Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516 Query: 403 SVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPR--MLHRSTQTTND 460 ++EE E + + S Q++ + + + + +K R L R + D Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576 Query: 461 GVCQSMCHDKYTKIFNDFKDRMKSDHKR-ETERVVREALEK---LRSEMEEEKRQAVNKA 516 + + + ++ + ++R++ KR E ER+ +E + R E EEE+RQ + K+ Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636 Query: 517 VANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQ 561 + + +R+ +Q++ + +E + +K+ + ++ + Q K++ Sbjct: 637 ----EEQEERRQQQLRREQQERREQRLKR--EEEEERLEQRLKRE 675 Score = 43.9 bits (102), Expect = 4e-04 Identities = 44/221 (19%), Positives = 98/221 (44%), Gaps = 13/221 (5%) Query: 348 DELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEP---RAKKGRRNQSV 404 +E + QR RE + + + E+R E++ E EQ + +E R ++ RR Q + Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351 Query: 405 EPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSP----RMLHRSTQTTND 460 ++EE E + + QE Q + + + ++L + L R Q + Sbjct: 352 RREQEEERREQQ-LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410 Query: 461 GVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANM 520 Q + ++ + + + R + + +R ++ +E E+ +EE+R + + Sbjct: 411 ---QQLRREQQLR--REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465 Query: 521 QGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQ 561 + E +R+ +Q+K +EE E KL + ++ + +++Q Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506 Score = 37.7 bits (86), Expect = 0.031 Identities = 38/219 (17%), Positives = 90/219 (41%), Gaps = 7/219 (3%) Query: 348 DELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKK--GRRNQSVE 405 D + R+ + W+ + E R EEE S E+ ++ R ++ R + E Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224 Query: 406 PKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSP---RMLHRSTQTTNDGV 462 K+++ + V +E + + + + +KL P R L + Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRK--RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282 Query: 463 CQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQG 522 Q + ++ + + R + +R+ E RE E+ R + E ++Q + + Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342 Query: 523 EMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQ 561 + +R+ +Q++ + +EE E+ + + ++ Q +++Q Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381 Score = 33.9 bits (76), Expect = 0.44 Identities = 42/208 (20%), Positives = 90/208 (43%), Gaps = 18/208 (8%) Query: 351 ELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEE 410 E ++FL+E + + + +R E E T EQL+ ++ R +K + + P++EE Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR--RQERYRKILEEEQLRPEREE 1761 Query: 411 PE-PETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHD 469 + E +E + Q E+ + +Q S R Q + Q + Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLRSQ------ESDRKFREEEQLRQEREEQQLRPQ 1815 Query: 470 KYTKIFNDFKDRMKSDH---KRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDR 526 + D K R + + + + +R+ +E + R+E + ++ + + E ++ Sbjct: 1816 Q-----RDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ 1870 Query: 527 KCKQVKE-KCKEEFVEEIKKLATQHKQL 553 K +Q +E K +EE + +K +H+Q+ Sbjct: 1871 KRRQERERKLREEHIRRQQKEEQRHRQV 1898 Score = 33.5 bits (75), Expect = 0.58 Identities = 56/280 (20%), Positives = 107/280 (38%), Gaps = 25/280 (8%) Query: 338 KRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKK 397 +R K+ E E Q+ L+ + + + E+ E E+ + E R K+ Sbjct: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674 Query: 398 GRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQT 457 + E + E E E IP +E + + Q+K S + R Q Sbjct: 675 EHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734 Query: 458 TND----------GVCQSMCH--DKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEM 505 + + H + + DF + +++ K E R A LR + Sbjct: 735 QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794 Query: 506 EE----EKRQAVNKAVANMQGEMDRKCKQVKEKCKE-EFVEEIKKLATQHKQLISQTKKK 560 E E+RQ + + E +++ +Q +E+ KE +F+EE ++L Q ++ Q +++ Sbjct: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL--QRRERAQQLQEE 852 Query: 561 QWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRR 600 + ++E S + Q+ W E +R RR Sbjct: 853 EDGLQEDQER------RRSQEQRRDQKWRWQLEEERKRRR 886 Score = 33.1 bits (74), Expect = 0.75 Identities = 41/221 (18%), Positives = 90/221 (40%), Gaps = 16/221 (7%) Query: 351 ELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEE 410 E + RE R + + E + E + + L+ +E R ++ R Q + KK + Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967 Query: 411 PEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDK 470 + E E P + E+ + ++L ++L + + + Sbjct: 968 QKEE----QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR----RQEWERQ 1019 Query: 471 YTKIFNDFKDRMKSDHKR--ETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKC 528 Y K KD ++ + ++ ER R E+ R EEE+ Q + + + E R+ Sbjct: 1020 YRK-----KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074 Query: 529 KQVKE-KCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEE 568 + ++ + +EE +E ++L + + + ++++ C EE Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115 Score = 32.7 bits (73), Expect = 0.98 Identities = 36/213 (16%), Positives = 87/213 (40%), Gaps = 15/213 (7%) Query: 357 LREGRFWKSKNEDRG-EEEAESSISSTSNEQLKVTQEPRAKKGRRNQSV-EPKKEEPEPE 414 LR+ R K + E++ +E E + ++ + +E + ++ R++ E + EPE Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514 Query: 415 TEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKI 474 + + Q++ + + + Q ++ R R + + + ++ Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLS- 1573 Query: 475 FNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEK 534 R + D K E E+ R ME+E++ + ++ E DRK ++ ++ Sbjct: 1574 ------RQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627 Query: 535 CKEEFVEEI------KKLATQHKQLISQTKKKQ 561 +E +++ +K + QL Q +++Q Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660 Score = 31.6 bits (70), Expect = 2.2 Identities = 44/228 (19%), Positives = 96/228 (42%), Gaps = 26/228 (11%) Query: 348 DELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPK 407 +E E +R RE ++ K K + EE+ E K ++ R KK R + ++ + Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQL------LGEEPEKRRRQEREKKYREEEELQQE 999 Query: 408 KEEPEPETEAVSSSQEIPTMP------QPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDG 461 +E+ E QE Q E+ + + +K +R + Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059 Query: 462 VCQSMCHDKYTKIFNDFKDRMKSDHK--RETERVVREALEKLRSE------MEEEKRQAV 513 Q + ++ T+ + + + + + + +E E+++RE EK R + EEE+ Q Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119 Query: 514 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQ 561 + + + E R+ + ++ +EE V++ + +QL+ + +K+ Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQ------EEEQLLREEPEKR 1161 Score = 31.6 bits (70), Expect = 2.2 Identities = 51/247 (20%), Positives = 102/247 (41%), Gaps = 43/247 (17%) Query: 367 NEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPT 426 + DR E E + +QL+ + R + Q ++E + E QE+ Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723 Query: 427 MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSD- 485 + E++ T+ ++L ++Y KI + + R + + Sbjct: 1724 KFREEEQLRQETEQEQLRR----------------------QERYRKILEEEQLRPEREE 1761 Query: 486 ---HKRETERVVREALEKLRSEMEEEK---RQAVNKAVANMQGEMDRKCKQVKEKCKE-- 537 ++E +R RE E+LR E EE++ +++ K Q +R+ +Q++ + ++ Sbjct: 1762 QQLRRQERDRKFREE-EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820 Query: 538 -EFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHW-HAEHK 595 + EE +L Q ++L + ++ Y EE+ + T S + +QE W E K Sbjct: 1821 YRWEEEQLQLEEQEQRLRQERDRQ---YRAEEQ------FATQEKSRREEQELWQEEEQK 1871 Query: 596 RTCRRKR 602 R R+R Sbjct: 1872 RRQERER 1878 >gi|74027249 tripartite motif-containing 33 protein isoform alpha [Homo sapiens] Length = 1127 Score = 45.4 bits (106), Expect = 1e-04 Identities = 37/151 (24%), Positives = 68/151 (45%), Gaps = 24/151 (15%) Query: 98 NHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVCRSIKK------- 150 N DW C C G++L C+ C +V+H C L S W C CR I K Sbjct: 886 NEDW-CAVCQNGGDLLCCEKCPKVFHLTCHVPTL-LSFPSGDWICTFCRDIGKPEVEYDC 943 Query: 151 ---KNTNKQEMGTYLRFIVSRMKERAI------DLNKKGKD---NKHPMYRRLVHSAVDV 198 +++ K + L + R ER + +L+ + ++ P Y +++ +D+ Sbjct: 944 DNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDL 1003 Query: 199 PTIQEKVNEGKYRSY---EEFKADAQLLLHN 226 T+++K+ + + Y ++F AD +L+ N Sbjct: 1004 STVKKKLQKKHSQHYQIPDDFVADVRLIFKN 1034 >gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens] Length = 634 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 8/64 (12%) Query: 83 EGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQC 142 E +W GD H+ +C C G++L+CD C RVYH CL + W C Sbjct: 432 EEHWPKGDI-------HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGM-WIC 483 Query: 143 PVCR 146 P C+ Sbjct: 484 PRCQ 487 >gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] Length = 840 Score = 44.3 bits (103), Expect = 3e-04 Identities = 48/221 (21%), Positives = 87/221 (39%), Gaps = 24/221 (10%) Query: 369 DRGEEEAESSISSTSNEQLKVTQE-PRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTM 427 + EE E+ ++ E+++V QE P ++ ++ E K E E ET S + Sbjct: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563 Query: 428 PQPIEKVSVSTQTKKLSASSPRMLHRSTQTTN---DGVCQSMCHDKYTKIFNDFKD---- 480 P +K V T T L + + + N + + + DK K ND K+ Sbjct: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEE 623 Query: 481 ---RMKSDHKRETERVVRE--------ALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCK 529 M+ E E+ V E LE + + E+ + + E+ + Sbjct: 624 YVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQ 683 Query: 530 QVKEKCKE-----EFVEEIKKLATQHKQLISQTKKKQWCYN 565 +K + +E + EE+ K Q+ ++IS K K+ Y+ Sbjct: 684 PIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYD 724 >gi|58530840 desmoplakin isoform I [Homo sapiens] Length = 2871 Score = 43.9 bits (102), Expect = 4e-04 Identities = 61/306 (19%), Positives = 125/306 (40%), Gaps = 39/306 (12%) Query: 297 KVMQKEDNQVDVRFFGHHHQRAW-----------IPSENIQDITVNIHRLHVKRSMGWKK 345 +++Q++++ H Q+A I E +Q +T N+ + H+ ++ Sbjct: 1667 QLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLML----EE 1722 Query: 346 ACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLK----VTQEPRAKKGRRN 401 L L LR GR +++ E S + ++N L+ + R ++ R Sbjct: 1723 ELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQ 1782 Query: 402 QSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLH--------R 453 + + +K+ E S + + Q E+ S+ + K L R+ + Sbjct: 1783 EIEKFQKQALEASNRIQESKNQCTQVVQ--ERESLLVKIKVLEQDKARLQRLEDELNRAK 1840 Query: 454 STQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQ-- 511 ST V Q + +K +I ND ++ K+ + R+ EA+ K+ SE E+ +R+ Sbjct: 1841 STLEAETRVKQRLECEKQ-QIQNDL-NQWKTQYSRK-----EEAIRKIESEREKSEREKN 1893 Query: 512 AVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKK-KQWCYNCEEEA 570 ++ + +Q E+ R ++ + K ++ E +L T+ + + K +Q Y E Sbjct: 1894 SLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRET 1953 Query: 571 MYHCCW 576 C W Sbjct: 1954 QTECEW 1959 >gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] Length = 680 Score = 43.9 bits (102), Expect = 4e-04 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 99 HDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVCR 146 H+ +C C G++L+CD C RVYH CL + W CP C+ Sbjct: 487 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGM-WICPRCQ 533 >gi|4758528 hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens] Length = 777 Score = 43.5 bits (101), Expect = 6e-04 Identities = 56/230 (24%), Positives = 95/230 (41%), Gaps = 49/230 (21%) Query: 362 FWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSS 421 +W+ K E E+ S T + + +T EP A+ G + + E P PET+ S Sbjct: 334 YWEKKQE-------EARKSPTPSAPVPLT-EPAAQPGEGHAAPTNVVENPLPETD----S 381 Query: 422 QEIPTMPQPIEKV--------------------SVSTQTKKLSASSPRMLHRSTQTTNDG 461 Q IP P + +V+T ++ ++ R TND Sbjct: 382 QPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNH----MRGRSITNDS 437 Query: 462 VCQSM------CHDKYTKIFNDFKDRM----KSDHKRETERVVREALEKLRSEMEEEKRQ 511 S+ H + ++ N +R K R R AL LR E E+ R+ Sbjct: 438 AVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRR 497 Query: 512 AVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQ 561 A +A Q ++ +K + +++K K+E++E ++LA Q Q Q K++Q Sbjct: 498 AAEEAERQRQIQLAQKLEIMRQK-KQEYLEVQRQLAIQRLQ--EQEKERQ 544 >gi|92859701 myosin VI [Homo sapiens] Length = 1285 Score = 43.1 bits (100), Expect = 7e-04 Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%) Query: 425 PTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKS 484 P M + I+ + +S T S M Q D + +S ++ + + + + Sbjct: 865 PEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSS-----EELLSALQKKKQQ 919 Query: 485 DHKRETERVVREALEKLRSEMEE-EKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEI 543 + + E R ++E +EK R EE EKR+ + M+ EM+ K KQ +E+ K+ +E Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEK 979 Query: 544 KKLATQHKQLISQTKKK 560 + A QL Q +++ Sbjct: 980 RIQAEVEAQLARQKEEE 996 >gi|153945728 microtubule-associated protein 1B [Homo sapiens] Length = 2468 Score = 43.1 bits (100), Expect = 7e-04 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 23/185 (12%) Query: 383 SNEQLKVTQEPRAKKGRRNQSVE---PKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQ 439 S E++ V ++ K + E P KEEP P V+ Q P+ ++ +V + Sbjct: 582 SKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKE 641 Query: 440 TKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALE 499 TK P + V + + K +K + K + E V +E + Sbjct: 642 TK----VKPEDKKEEKEKPKKEVAK-----------KEDKTPIKKEEKPKKEEVKKEVKK 686 Query: 500 KLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEF--VEEIKKLATQHKQL---I 554 +++ E ++E ++ V K + + + K ++ KE KEE +EIKKL K+ + Sbjct: 687 EIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPL 746 Query: 555 SQTKK 559 S+ KK Sbjct: 747 SEAKK 751 Score = 35.4 bits (80), Expect = 0.15 Identities = 38/178 (21%), Positives = 76/178 (42%), Gaps = 19/178 (10%) Query: 385 EQLKVTQEPRAKKGRRNQSVEPKKEEP-EPETEAVSSSQEIPTMPQPIEKVSVSTQTKKL 443 E KV + K + V KK++P + ET+ + +E+P+ +P V K+ Sbjct: 567 EVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEP-SPVKAEVAEKQA 625 Query: 444 SASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRS 503 + P+ T K TK+ K K + K + ++ V + +K Sbjct: 626 TDVKPKAAKEKTVK------------KETKV----KPEDKKEEKEKPKKEVAKKEDKTPI 669 Query: 504 EMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKK 560 + EE+ ++ K + + + K + KE KE +E+KK + + K+ + + +K+ Sbjct: 670 KKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKE 727 Score = 33.1 bits (74), Expect = 0.75 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 4/95 (4%) Query: 356 FLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAK-KGRRNQSVEPKKEEPEPE 414 ++RE R + +DR EE+ + +I EQ + + K + R + EP+K E E Sbjct: 985 YIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDY 1044 Query: 415 TEA-VSSSQEIPTMPQPIEKVSVSTQTKKLSASSP 448 A V + E + + ++T TK+L A SP Sbjct: 1045 VMAVVDKAAEAGGAEE--QYGFLTTPTKQLGAQSP 1077 Score = 31.2 bits (69), Expect = 2.9 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 14/107 (13%) Query: 366 KNEDRGEEEAESSISSTSNEQLKVTQEPRAKKG-RRNQSVEPKKEEPEPETEAVSSSQEI 424 K E + EE+ E E K T KK ++ + E KKEE EP+ +EI Sbjct: 685 KKEIKKEEKKEPK-----KEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK-------KEI 732 Query: 425 PTMPQPIEKVSVS-TQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDK 470 +P+ +K S ++ KK +A P++ + D V +K Sbjct: 733 KKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEK 779 >gi|28329422 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c [Homo sapiens] Length = 567 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 8/116 (6%) Query: 486 HKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQV--KEKCK-EEFVEE 542 H+ + V E +K + E KRQA+ + + E +RK + E+ K E V E Sbjct: 397 HRPASGYVPEEIWKKAEEAVNEVKRQAMTE-LQKAVSEAERKAHDMITTERAKMERTVAE 455 Query: 543 IKKLATQHKQLI--SQTKKKQWCYNCEEEAMYHC--CWNTSYCSIKCQQEHWHAEH 594 K+ A + + Q + C+NC +A C C YC CQ + W H Sbjct: 456 AKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHH 511 >gi|28329419 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c [Homo sapiens] Length = 567 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 8/116 (6%) Query: 486 HKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQV--KEKCK-EEFVEE 542 H+ + V E +K + E KRQA+ + + E +RK + E+ K E V E Sbjct: 397 HRPASGYVPEEIWKKAEEAVNEVKRQAMTE-LQKAVSEAERKAHDMITTERAKMERTVAE 455 Query: 543 IKKLATQHKQLI--SQTKKKQWCYNCEEEAMYHC--CWNTSYCSIKCQQEHWHAEH 594 K+ A + + Q + C+NC +A C C YC CQ + W H Sbjct: 456 AKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHH 511 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.130 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,484,212 Number of Sequences: 37866 Number of extensions: 1118774 Number of successful extensions: 8797 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 161 Number of HSP's successfully gapped in prelim test: 536 Number of HSP's that attempted gapping in prelim test: 6978 Number of HSP's gapped (non-prelim): 2075 length of query: 602 length of database: 18,247,518 effective HSP length: 108 effective length of query: 494 effective length of database: 14,157,990 effective search space: 6994047060 effective search space used: 6994047060 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.