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Search of human proteins with 238550098
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238550098 transmembrane channel-like 7 isoform a [Homo
sapiens]
(723 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] 1448 0.0
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] 1234 0.0
gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] 434 e-121
gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] 434 e-121
gi|23943900 transmembrane channel-like 8 [Homo sapiens] 366 e-101
gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] 234 3e-61
gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] 234 3e-61
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 229 7e-60
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap... 216 5e-56
gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] 207 3e-53
gi|187608784 transmembrane channel-like 6 [Homo sapiens] 199 6e-51
gi|187608791 transmembrane channel-like 6 [Homo sapiens] 199 6e-51
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 146 6e-35
gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo... 38 0.029
gi|83700231 cytotoxic T-lymphocyte-associated protein 4 isoform ... 33 0.71
gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform ... 33 0.71
gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens] 33 0.93
gi|106067657 luteinizing hormone/choriogonadotropin receptor pre... 32 2.1
gi|153945816 Nanog homeobox [Homo sapiens] 30 6.0
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 30 6.0
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 30 6.0
gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 30 6.0
gi|90421313 cystic fibrosis transmembrane conductance regulator ... 30 7.9
gi|21536376 ATP-binding cassette, sub-family A member 1 [Homo sa... 30 7.9
>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
Length = 723
Score = 1448 bits (3748), Expect = 0.0
Identities = 723/723 (100%), Positives = 723/723 (100%)
Query: 1 MSESSGSALQPGRPSRQPAVHPENLSLDSSCFSSPPVNFLQELPSYRSIARRRTTVHSRD 60
MSESSGSALQPGRPSRQPAVHPENLSLDSSCFSSPPVNFLQELPSYRSIARRRTTVHSRD
Sbjct: 1 MSESSGSALQPGRPSRQPAVHPENLSLDSSCFSSPPVNFLQELPSYRSIARRRTTVHSRD 60
Query: 61 KQSGTLLKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQW 120
KQSGTLLKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQW
Sbjct: 61 KQSGTLLKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQW 120
Query: 121 KRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLI 180
KRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLI
Sbjct: 121 KRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLI 180
Query: 181 IFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFL 240
IFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFL
Sbjct: 181 IFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFL 240
Query: 241 EETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEE 300
EETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEE
Sbjct: 241 EETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEE 300
Query: 301 HFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYS 360
HFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYS
Sbjct: 301 HFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYS 360
Query: 361 LRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFI 420
LRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFI
Sbjct: 361 LRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFI 420
Query: 421 TPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYN 480
TPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYN
Sbjct: 421 TPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYN 480
Query: 481 QKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAI 540
QKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAI
Sbjct: 481 QKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAI 540
Query: 541 PDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSN 600
PDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSN
Sbjct: 541 PDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSN 600
Query: 601 FFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPSSLQSFIH 660
FFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPSSLQSFIH
Sbjct: 601 FFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPSSLQSFIH 660
Query: 661 GVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQRD 720
GVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQRD
Sbjct: 661 GVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQRD 720
Query: 721 MRN 723
MRN
Sbjct: 721 MRN 723
>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
Length = 613
Score = 1234 bits (3193), Expect = 0.0
Identities = 613/613 (100%), Positives = 613/613 (100%)
Query: 111 MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL 170
MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL
Sbjct: 1 MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL 60
Query: 171 VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI 230
VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI
Sbjct: 61 VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI 120
Query: 231 IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG 290
IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG
Sbjct: 121 IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG 180
Query: 291 FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER 350
FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER
Sbjct: 181 FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER 240
Query: 351 TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP 410
TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP
Sbjct: 241 TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP 300
Query: 411 SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD 470
SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD
Sbjct: 301 SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD 360
Query: 471 DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI 530
DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI
Sbjct: 361 DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI 420
Query: 531 QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS 590
QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS
Sbjct: 421 QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS 480
Query: 591 PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST 650
PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST
Sbjct: 481 PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST 540
Query: 651 FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL 710
FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL
Sbjct: 541 FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL 600
Query: 711 IQKLTEAQRDMRN 723
IQKLTEAQRDMRN
Sbjct: 601 IQKLTEAQRDMRN 613
>gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]
Length = 706
Score = 434 bits (1117), Expect = e-121
Identities = 257/688 (37%), Positives = 392/688 (56%), Gaps = 40/688 (5%)
Query: 40 LQELPSYRSIARRRTTV------HSRDKQSGTLLKP-TDSYSSQLEDRIAENLSSHSLRN 92
L ELPS ++ R V ++ G K T+ ++L+D H R
Sbjct: 34 LNELPSAATLRYRDPGVLPWGALEEEEEDGGRSRKAFTEVTQTELQD-------PHPSRE 86
Query: 93 YALNISEKR--RLRDIQETQMKYLS--EWDQWKRYSSKSWKRFLEKAREMTTHLELWRED 148
+ +R R R+ Q+ Y S + D+W R +S EK +E L+ W
Sbjct: 87 LPWPMQARRAHRQRNASRDQVVYGSGTKTDRWARLLRRS----KEKTKEGLRSLQPWAWT 142
Query: 149 IRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKD 208
++ I G+FG G +SYFS LRFL+LLN++ +++ + LLP L + P D
Sbjct: 143 LKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWL------GGAPPGPPGPD 196
Query: 209 MDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAY 268
+ C Y S GL+ F + + +LLSG G+LE + LFYG Y L + Y
Sbjct: 197 ISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP--------RLAVTY 248
Query: 269 LLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHS 328
L A + LL I+ RSV G K L+ E SY +++F+ WDF + L+
Sbjct: 249 LCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQR 308
Query: 329 SLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQ 388
+ YEL+ +LEE +R++ A RT + R++ +R+ LN +V+A+LGA FY +Y AT +
Sbjct: 309 IILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGCTV 368
Query: 389 EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCV 448
E + + + + L + YLPSI I NF+ P +F I E Y+ +I +LR V
Sbjct: 369 ELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTV 428
Query: 449 FMRLATICVLVFTLGSKITSCDD---DTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFII 505
F+RLA++ VL+F+L ++IT D + C CGYN K PCWET +GQEMYKL++FD +
Sbjct: 429 FLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLT 488
Query: 506 ILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLP 565
+LAV L + FPRKLL C L + G QEF +PD VLG++Y QT+ W+G+FF PLLP
Sbjct: 489 VLAVALLIQFPRKLLCGLCPGA-LGRLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLP 547
Query: 566 AIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRI 625
+ T+KF+++FY+K+ +L TC P+ R FRAS +NFFF LVLL+GL ++ +PL SI I
Sbjct: 548 LLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPLLYSIFLI 607
Query: 626 PSSKACGPFTNFNTTWEVIPKTVSTFPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIAL 685
P SK CGPF ++ W IP+++S+ P + Q+F+ + ++AFAVP +I ++M Y +AL
Sbjct: 608 PPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLLLISSILMAYTVAL 667
Query: 686 AGAHKRVVIQLREQLSLESRDKCYLIQK 713
A ++ R++ +L+ Q E+++K +L ++
Sbjct: 668 ANSYGRLISELKRQRQTEAQNKVFLARR 695
>gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]
Length = 712
Score = 434 bits (1117), Expect = e-121
Identities = 257/688 (37%), Positives = 392/688 (56%), Gaps = 40/688 (5%)
Query: 40 LQELPSYRSIARRRTTV------HSRDKQSGTLLKP-TDSYSSQLEDRIAENLSSHSLRN 92
L ELPS ++ R V ++ G K T+ ++L+D H R
Sbjct: 40 LNELPSAATLRYRDPGVLPWGALEEEEEDGGRSRKAFTEVTQTELQD-------PHPSRE 92
Query: 93 YALNISEKR--RLRDIQETQMKYLS--EWDQWKRYSSKSWKRFLEKAREMTTHLELWRED 148
+ +R R R+ Q+ Y S + D+W R +S EK +E L+ W
Sbjct: 93 LPWPMQARRAHRQRNASRDQVVYGSGTKTDRWARLLRRS----KEKTKEGLRSLQPWAWT 148
Query: 149 IRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKD 208
++ I G+FG G +SYFS LRFL+LLN++ +++ + LLP L + P D
Sbjct: 149 LKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWL------GGAPPGPPGPD 202
Query: 209 MDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAY 268
+ C Y S GL+ F + + +LLSG G+LE + LFYG Y L + Y
Sbjct: 203 ISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP--------RLAVTY 254
Query: 269 LLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHS 328
L A + LL I+ RSV G K L+ E SY +++F+ WDF + L+
Sbjct: 255 LCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQR 314
Query: 329 SLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQ 388
+ YEL+ +LEE +R++ A RT + R++ +R+ LN +V+A+LGA FY +Y AT +
Sbjct: 315 IILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGCTV 374
Query: 389 EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCV 448
E + + + + L + YLPSI I NF+ P +F I E Y+ +I +LR V
Sbjct: 375 ELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTV 434
Query: 449 FMRLATICVLVFTLGSKITSCDD---DTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFII 505
F+RLA++ VL+F+L ++IT D + C CGYN K PCWET +GQEMYKL++FD +
Sbjct: 435 FLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLT 494
Query: 506 ILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLP 565
+LAV L + FPRKLL C L + G QEF +PD VLG++Y QT+ W+G+FF PLLP
Sbjct: 495 VLAVALLIQFPRKLLCGLCPGA-LGRLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLP 553
Query: 566 AIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRI 625
+ T+KF+++FY+K+ +L TC P+ R FRAS +NFFF LVLL+GL ++ +PL SI I
Sbjct: 554 LLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPLLYSIFLI 613
Query: 626 PSSKACGPFTNFNTTWEVIPKTVSTFPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIAL 685
P SK CGPF ++ W IP+++S+ P + Q+F+ + ++AFAVP +I ++M Y +AL
Sbjct: 614 PPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLLLISSILMAYTVAL 673
Query: 686 AGAHKRVVIQLREQLSLESRDKCYLIQK 713
A ++ R++ +L+ Q E+++K +L ++
Sbjct: 674 ANSYGRLISELKRQRQTEAQNKVFLARR 701
>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
Length = 726
Score = 366 bits (940), Expect = e-101
Identities = 220/638 (34%), Positives = 352/638 (55%), Gaps = 30/638 (4%)
Query: 86 SSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELW 145
S +R + +KR + ++E W +W+R +R E A+ + L LW
Sbjct: 32 SGTPVRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLW 91
Query: 146 REDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIP 205
+ I G FGTGI+SYF+FLRFL+LLNL+ L+ VLLP++ + P
Sbjct: 92 EGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPG------P 145
Query: 206 FKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLP 265
++ QC S G++ F++ + +L+G F T LFYG Y + + Y +
Sbjct: 146 TLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYRVGPES--SSVYSIR 202
Query: 266 LAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADL 325
LAYLLS +A L L ++R V+G + + + K+F+ WDFCI + A +
Sbjct: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262
Query: 326 KHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATV 385
K + E + +LEE R Q + ++T +T L +N + ++ AI+ AT
Sbjct: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322
Query: 386 FSQEHMKKEIDKMVFGENLFIL--YLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLT 443
+SQ++ + E+LF+L YLP VI L NF+ P++F +++ E+Y P E+ LT
Sbjct: 323 YSQDNKE---------ESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT 373
Query: 444 ILRCVFMRLATICVLVFTLGSKITSC--DDDTCDLCGYNQKLYPCWETQVGQEMYKLMIF 501
++ CV ++LA++ + +LG I D +C+ GYN Y CWE VG+E+YKL IF
Sbjct: 374 LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF 433
Query: 502 DFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWG---QQEFAIPDNVLGIVYGQTICWIGA 558
+F++ +A V PR+LLV S + W ++EF +P NVL IV GQT+ W+G
Sbjct: 434 NFLLTVAFAFLVTLPRRLLVDRFSG----RFWAWLEREEFLVPKNVLDIVAGQTVTWMGL 489
Query: 559 FFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAIIPL 618
F+ PLLP + ++ + FY+K+++LL R S RPFRAS+S FFF LVLL+GL LA +PL
Sbjct: 490 FYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPL 549
Query: 619 TISISRIPSSKACGPFTNFNTTWEVIPKTVST-FPSSLQSFIHGVTSEAFAVPFFMIICL 677
+S I SS CG FTN++ W+V+P+ V+ P Q +H + S AF+ P +++ L
Sbjct: 550 GYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSL 609
Query: 678 IMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLT 715
++ ++ A+ R + +LR+QL + ++K +L++ L+
Sbjct: 610 VLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLS 647
>gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]
Length = 1006
Score = 234 bits (596), Expect = 3e-61
Identities = 177/647 (27%), Positives = 308/647 (47%), Gaps = 73/647 (11%)
Query: 89 SLRNYALNISEKRRLRDI-------QETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTH 141
++RN + EKR LR I Q ++ L+ Q S++++R E+
Sbjct: 368 AIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNSLSEILNS 427
Query: 142 LELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSF 201
+ LW++ ++ I GKFGT + SYF+FLR+L+ N+ F++ N SF
Sbjct: 428 ISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFIL-----------------NFSF 470
Query: 202 VLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNF- 260
++IP + K+ T+ +GL +F +G G+ +T ++YG YT ++ N
Sbjct: 471 IIIPQFTVAKKNTL---QFTGLEFF--------TGVGYFRDTVMYYGFYTNSTIQHGNSG 519
Query: 261 -TYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITN 319
+Y++ LAY+ + A L ++ + F+ N I + IF WDF +T+
Sbjct: 520 ASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-WDFTVTH 578
Query: 320 RSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYA 379
LK +L E+R +L E +RQ+ ++ T + + +S + + V AC A
Sbjct: 579 EKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAA 636
Query: 380 IYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYS-PGF 438
+Y ++ E +K + +L LP V++ N P I++ E Y P
Sbjct: 637 VYYLAEYNLEFLKTHSNPGA------VLLLP-FVVSCINLAVPCIYSMFRLVERYEMPRH 689
Query: 439 EIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEMYKL 498
E+ + ++R +F++++ I +L + + + ++ CWET +GQ++Y+L
Sbjct: 690 EVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE-------------CWETLIGQDIYRL 736
Query: 499 MIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGA 558
++ DF+ L + +F R+++ +LI G QEF I NVL ++Y QT+ WIG
Sbjct: 737 LLMDFVFSLVNSFLGEFLRRII-----GMQLITSLGLQEFDIARNVLELIYAQTLVWIGI 791
Query: 559 FFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAII-P 617
FF PLLP I + I+FY K SL+ +P + +RAS FF+ +L ++
Sbjct: 792 FFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCT 851
Query: 618 LTISISRIPSSKACGPFTNFNTTWEVIPK---TVSTFPSSL---QSFIHGVTSEAFAVPF 671
L I+I R+ S CGPF I T+ST P L + + + S F
Sbjct: 852 LAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIYRNLIGSVHFFFIL 911
Query: 672 FMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQ 718
+I+ +I + + + K ++ L EQ+ E +DK +LI+KL + Q
Sbjct: 912 TLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQ 958
>gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]
Length = 760
Score = 234 bits (596), Expect = 3e-61
Identities = 177/647 (27%), Positives = 308/647 (47%), Gaps = 73/647 (11%)
Query: 89 SLRNYALNISEKRRLRDI-------QETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTH 141
++RN + EKR LR I Q ++ L+ Q S++++R E+
Sbjct: 122 AIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNSLSEILNS 181
Query: 142 LELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSF 201
+ LW++ ++ I GKFGT + SYF+FLR+L+ N+ F++ N SF
Sbjct: 182 ISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFIL-----------------NFSF 224
Query: 202 VLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNF- 260
++IP + K+ T+ +GL +F +G G+ +T ++YG YT ++ N
Sbjct: 225 IIIPQFTVAKKNTL---QFTGLEFF--------TGVGYFRDTVMYYGFYTNSTIQHGNSG 273
Query: 261 -TYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITN 319
+Y++ LAY+ + A L ++ + F+ N I + IF WDF +T+
Sbjct: 274 ASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-WDFTVTH 332
Query: 320 RSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYA 379
LK +L E+R +L E +RQ+ ++ T + + +S + + V AC A
Sbjct: 333 EKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAA 390
Query: 380 IYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYS-PGF 438
+Y ++ E +K + +L LP V++ N P I++ E Y P
Sbjct: 391 VYYLAEYNLEFLKTHSNPGA------VLLLP-FVVSCINLAVPCIYSMFRLVERYEMPRH 443
Query: 439 EIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEMYKL 498
E+ + ++R +F++++ I +L + + + ++ CWET +GQ++Y+L
Sbjct: 444 EVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE-------------CWETLIGQDIYRL 490
Query: 499 MIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGA 558
++ DF+ L + +F R+++ +LI G QEF I NVL ++Y QT+ WIG
Sbjct: 491 LLMDFVFSLVNSFLGEFLRRII-----GMQLITSLGLQEFDIARNVLELIYAQTLVWIGI 545
Query: 559 FFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAII-P 617
FF PLLP I + I+FY K SL+ +P + +RAS FF+ +L ++
Sbjct: 546 FFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCT 605
Query: 618 LTISISRIPSSKACGPFTNFNTTWEVIPK---TVSTFPSSL---QSFIHGVTSEAFAVPF 671
L I+I R+ S CGPF I T+ST P L + + + S F
Sbjct: 606 LAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIYRNLIGSVHFFFIL 665
Query: 672 FMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQ 718
+I+ +I + + + K ++ L EQ+ E +DK +LI+KL + Q
Sbjct: 666 TLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQ 712
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 229 bits (584), Expect = 7e-60
Identities = 168/645 (26%), Positives = 292/645 (45%), Gaps = 77/645 (11%)
Query: 117 WDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLV 176
W +K +K W +FL W I++IE +FG+ + SYF FLR++ +N+V
Sbjct: 142 WFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMV 201
Query: 177 IFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSG 236
+F++ F L++LP L + +P + ++ G++Y ++
Sbjct: 202 LFILTFSLIMLPEYLWGLPYGSLPRKTVP------RAEEASAANFGVLYDFN-------- 247
Query: 237 TGFLEETSLFYGHY----TIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFK 292
G + + LFYG+Y TI + F+ LPL+Y L I + S L ++K +
Sbjct: 248 -GLAQYSVLFYGYYDNKRTIGWMNFR-----LPLSYFLVGIMCIGYSFLVVLKAMTKNIG 301
Query: 293 INLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTS 352
+ + F ++ K+F WD+ I N AD K +S+ + + EE+ A +
Sbjct: 302 DDGGGDDNTF-NFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEK-----AAQVE 355
Query: 353 EETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSI 412
E I LR N V LG Y I+ A SQE +++ D + + E + ++
Sbjct: 356 ENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEM----NM 411
Query: 413 VITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDD 472
V++L P +F EDY P ++ + R + L + V + L +I + ++
Sbjct: 412 VMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEE 471
Query: 473 TCDLCGYNQKLY-------------------------------PCWETQVGQEMYKLMIF 501
L N L+ PCWET VGQE +L +
Sbjct: 472 E-KLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVS 530
Query: 502 DFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EFAIPDNVLGIVYGQTIC 554
D + L DF R V +C+ C CW + EF I NVL +++ Q +
Sbjct: 531 DVLTTYVTILIGDFLRACFVRFCNYC---WCWDLEYGYPSYTEFDISGNVLALIFNQGMI 587
Query: 555 WIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLA 614
W+G+FF+P LP I L+ Y + W+++ P R F+AS SN F+L +LL+ L L+
Sbjct: 588 WMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLS 647
Query: 615 IIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVS-TFPSSLQSFIHGVTSEAFAVPFFM 673
+P+ I +P S CGPF+ N +EVI +T+ FPS + + +++ + +
Sbjct: 648 TMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVIL 707
Query: 674 IICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQ 718
++ L ++Y A A K + L++++ +++ + +K+ A+
Sbjct: 708 VMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAAR 752
>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
sapiens]
Length = 906
Score = 216 bits (551), Expect = 5e-56
Identities = 184/774 (23%), Positives = 335/774 (43%), Gaps = 110/774 (14%)
Query: 3 ESSGSALQPGRPSRQPAV---HPENLS------LDSSCFSSPPVNFLQELPSYRSIARRR 53
E +G + PG P R+ H E L + +C + + +R
Sbjct: 58 ERAGGSPSPGSPRRKQTGRRRHREELGEQERGEAERTCEGRRKRDERASFQERTAAPKRE 117
Query: 54 TTVHSRDKQSGTLLKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRL---------- 103
+ R+++S KP S + E+LS L + EK++L
Sbjct: 118 KEIPRREEKSKRQKKPRSSSLASSASG-GESLSEEELAQILEQVEEKKKLIATMRSKPWP 176
Query: 104 --------RDIQETQMKYLSEWDQ--------WKRYSSKSWKRFLEKAREMTTHLELWRE 147
R+ QE KY + +K +K W +F T W
Sbjct: 177 MAKKLTELREAQEFVEKYEGALGKGKGKQLYAYKMLMAKKWVKFKRDFDNFKTQCIPWEM 236
Query: 148 DIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFK 207
I+ IE FG+ + SYF FLR++ +NLV+F +IF LV++P +L + +P
Sbjct: 237 KIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSIPRKTVPRA 296
Query: 208 DMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHY----TIDGVKFQNFTYD 263
+ +K +S + D G+++ ++LFYG+Y TI ++ Y
Sbjct: 297 EEEKAMD------------FSVLWDF---EGYIKYSALFYGYYNNQRTIGWLR-----YR 336
Query: 264 LPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMA 323
LP+AY + ++ SL+ +++ + + E ++ K+F WD+ I N A
Sbjct: 337 LPMAYFMVGVSVFGYSLIIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLIGNSETA 396
Query: 324 DLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYS-LRLFLNCIVLAVLGACFYAIYV 382
D K++S+ + + +E+ E EE I + LR+ N +++ L Y IY
Sbjct: 397 DNKYASITTSFKESIVDEQ------ESNKEENIHLTRFLRVLANFLIICCLCGSGYLIYF 450
Query: 383 ATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRL 442
SQ+ K + + IV++L P +F I E+Y P ++
Sbjct: 451 VVKRSQQFSKMQNVSWYERNEV------EIVMSLLGMFCPPLFETIAALENYHPRTGLKW 504
Query: 443 TILRCVFMRLATICVLVFTLGSKI--TSCDDDTC------------DLCGYNQK-----L 483
+ R + L + + L + +++T + G+N+ L
Sbjct: 505 QLGRIFALFLGNLYTFLLALMDDVHLKLANEETIKNITHWTLFNYYNSSGWNESVPRPPL 564
Query: 484 YP-------CWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ 536
+P CWET VG E +L + D ++ L DF R V + + C CW +
Sbjct: 565 HPADVPRGSCWETAVGIEFMRLTVSDMLVTYITILLGDFLRACFVRFMNYC---WCWDLE 621
Query: 537 -------EFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRP 589
EF I NVLG+++ Q + W+G+F++P L I L+ + Y + W+++ + P
Sbjct: 622 AGFPSYAEFDISGNVLGLIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVP 681
Query: 590 SPRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTV- 648
R F+AS SN F++ +LL+ L L+++P+ +I +P S CGPF+ N ++V+ +T+
Sbjct: 682 HERVFKASRSNNFYMGLLLLVLFLSLLPVAYTIMSLPPSFDCGPFSGKNRMYDVLQETIE 741
Query: 649 STFPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSL 702
+ FP+ L + + +P +++ L ++Y +++ + R QLR+++ +
Sbjct: 742 NDFPTFLGKIFAFLANPGLIIPAILLMFLAIYYLNSVSKSLSRANAQLRKKIQV 795
>gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]
Length = 948
Score = 207 bits (527), Expect = 3e-53
Identities = 151/548 (27%), Positives = 264/548 (48%), Gaps = 67/548 (12%)
Query: 89 SLRNYALNISEKRRLRDI-------QETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTH 141
++RN + EKR LR I Q ++ L+ Q S++++R E+
Sbjct: 368 AIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNSLSEILNS 427
Query: 142 LELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSF 201
+ LW++ ++ I GKFGT + SYF+FLR+L+ N+ F++ N SF
Sbjct: 428 ISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFIL-----------------NFSF 470
Query: 202 VLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNF- 260
++IP + K+ T+ +GL +F +G G+ +T ++YG YT ++ N
Sbjct: 471 IIIPQFTVAKKNTL---QFTGLEFF--------TGVGYFRDTVMYYGFYTNSTIQHGNSG 519
Query: 261 -TYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITN 319
+Y++ LAY+ + A L ++ + F+ N I + IF WDF +T+
Sbjct: 520 ASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-WDFTVTH 578
Query: 320 RSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYA 379
LK +L E+R +L E +RQ+ ++ T + + +S + + V AC A
Sbjct: 579 EKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAA 636
Query: 380 IYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYS-PGF 438
+Y ++ E +K + +L LP V++ N P I++ E Y P
Sbjct: 637 VYYLAEYNLEFLKTHSNPGA------VLLLP-FVVSCINLAVPCIYSMFRLVERYEMPRH 689
Query: 439 EIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEMYKL 498
E+ + ++R +F++++ I +L + + + ++ CWET +GQ++Y+L
Sbjct: 690 EVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE-------------CWETLIGQDIYRL 736
Query: 499 MIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGA 558
++ DF+ L + +F R+++ +LI G QEF I NVL ++Y QT+ WIG
Sbjct: 737 LLMDFVFSLVNSFLGEFLRRII-----GMQLITSLGLQEFDIARNVLELIYAQTLVWIGI 791
Query: 559 FFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAII-P 617
FF PLLP I + I+FY K SL+ +P + +RAS FF+ +L ++
Sbjct: 792 FFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCT 851
Query: 618 LTISISRI 625
L I+I RI
Sbjct: 852 LAITIWRI 859
>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 199 bits (507), Expect = 6e-51
Identities = 189/740 (25%), Positives = 326/740 (44%), Gaps = 120/740 (16%)
Query: 24 NLSLDSSCFSSPPV--NFLQEL-PSYR--SIARRRTTVHSRDKQSGTLLKPTDSYSSQLE 78
N ++ C SS P+ NF++ PS R + T + +KQS L+K S +
Sbjct: 103 NRTVQLRCRSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEEKQS-LLVKELQSLAVAQR 161
Query: 79 DRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQWKRYSSK----SWKRFLEK 134
D H LR L+++EKR LR+ T +W+ S L
Sbjct: 162 D--------HMLRGMPLSLAEKRSLREKSRTPR------GKWRGQPGSGGVCSCCGRLRY 207
Query: 135 AREMTTH------------LELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIF 182
A + H L WR ++ I G+FG+ + SYF FL+ L+ N ++ L++
Sbjct: 208 ACVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLV 267
Query: 183 MLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEE 242
++ P + + + V CT ++LL+G G
Sbjct: 268 AFIMGPQVAFPPALPGPAPV----------CTG---------------LELLTGAGCFTH 302
Query: 243 TSLFYGHYT-----------IDGV----KFQNFTYDLPLAYLLSTIASLALSLLWIVKRS 287
T ++YGHY+ +DG + Y++PLAYL + S ++ + +V
Sbjct: 303 TVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSM 362
Query: 288 VEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMR--- 344
F + R + +F WD+ +T + + L+ ++R L+ L E ++R
Sbjct: 363 AHSFGESY-RVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSP 421
Query: 345 QKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENL 404
+ + R + + L + L LG VFS+ ++ G+
Sbjct: 422 RSVCGRLRQAAV--------LGLVWLLCLGTALGCAVAVHVFSEFMIQSP---EAAGQEA 470
Query: 405 FILYLPSIVITLANFITPMIFAKIIRYEDY-SPGFEIRLTILRCVFMRLATICVLVFT-L 462
+L LP +V+ L N P + + E + SP E+ + I R + ++LA + L + L
Sbjct: 471 VLLVLP-LVVGLLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWL 529
Query: 463 GSKITSCDDDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVT 522
G ++ CWE VGQE+Y+ ++ DF+++L TLF + +++
Sbjct: 530 GRRVGVLQGQ-------------CWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRII-- 574
Query: 523 YCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWS 582
S K ++ + EF I NVL ++YGQT+ W+G FSPLLPA+ +K +++FYVK+ S
Sbjct: 575 ---SEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTS 631
Query: 583 LLYTCRPSPRPFRASNSNFFFLLVLLIGLCL-AIIPLTISISRIPSSKACGPFTNFNTTW 641
LL C+ RP+ AS+ + FL +L L A + L ++ ++ S CGPF +T +
Sbjct: 632 LLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMY 691
Query: 642 EVIPKTVSTFPS-----SLQSFIHGVTSEAFAVPFFM--IICLIMFYFIALAGAHKRVVI 694
E V + S ++H E F + ++ +++ I + ++V+
Sbjct: 692 EAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVIC 751
Query: 695 QLREQLSLESRDKCYLIQKL 714
L+EQ+S E DK +LI KL
Sbjct: 752 LLKEQISNEGEDKIFLINKL 771
>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 199 bits (507), Expect = 6e-51
Identities = 189/740 (25%), Positives = 326/740 (44%), Gaps = 120/740 (16%)
Query: 24 NLSLDSSCFSSPPV--NFLQEL-PSYR--SIARRRTTVHSRDKQSGTLLKPTDSYSSQLE 78
N ++ C SS P+ NF++ PS R + T + +KQS L+K S +
Sbjct: 103 NRTVQLRCRSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEEKQS-LLVKELQSLAVAQR 161
Query: 79 DRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQWKRYSSK----SWKRFLEK 134
D H LR L+++EKR LR+ T +W+ S L
Sbjct: 162 D--------HMLRGMPLSLAEKRSLREKSRTPR------GKWRGQPGSGGVCSCCGRLRY 207
Query: 135 AREMTTH------------LELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIF 182
A + H L WR ++ I G+FG+ + SYF FL+ L+ N ++ L++
Sbjct: 208 ACVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLV 267
Query: 183 MLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEE 242
++ P + + + V CT ++LL+G G
Sbjct: 268 AFIMGPQVAFPPALPGPAPV----------CTG---------------LELLTGAGCFTH 302
Query: 243 TSLFYGHYT-----------IDGV----KFQNFTYDLPLAYLLSTIASLALSLLWIVKRS 287
T ++YGHY+ +DG + Y++PLAYL + S ++ + +V
Sbjct: 303 TVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSM 362
Query: 288 VEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMR--- 344
F + R + +F WD+ +T + + L+ ++R L+ L E ++R
Sbjct: 363 AHSFGESY-RVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSP 421
Query: 345 QKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENL 404
+ + R + + L + L LG VFS+ ++ G+
Sbjct: 422 RSVCGRLRQAAV--------LGLVWLLCLGTALGCAVAVHVFSEFMIQSP---EAAGQEA 470
Query: 405 FILYLPSIVITLANFITPMIFAKIIRYEDY-SPGFEIRLTILRCVFMRLATICVLVFT-L 462
+L LP +V+ L N P + + E + SP E+ + I R + ++LA + L + L
Sbjct: 471 VLLVLP-LVVGLLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWL 529
Query: 463 GSKITSCDDDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVT 522
G ++ CWE VGQE+Y+ ++ DF+++L TLF + +++
Sbjct: 530 GRRVGVLQGQ-------------CWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRII-- 574
Query: 523 YCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWS 582
S K ++ + EF I NVL ++YGQT+ W+G FSPLLPA+ +K +++FYVK+ S
Sbjct: 575 ---SEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTS 631
Query: 583 LLYTCRPSPRPFRASNSNFFFLLVLLIGLCL-AIIPLTISISRIPSSKACGPFTNFNTTW 641
LL C+ RP+ AS+ + FL +L L A + L ++ ++ S CGPF +T +
Sbjct: 632 LLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMY 691
Query: 642 EVIPKTVSTFPS-----SLQSFIHGVTSEAFAVPFFM--IICLIMFYFIALAGAHKRVVI 694
E V + S ++H E F + ++ +++ I + ++V+
Sbjct: 692 EAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVIC 751
Query: 695 QLREQLSLESRDKCYLIQKL 714
L+EQ+S E DK +LI KL
Sbjct: 752 LLKEQISNEGEDKIFLINKL 771
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 146 bits (369), Expect = 6e-35
Identities = 85/231 (36%), Positives = 128/231 (55%), Gaps = 12/231 (5%)
Query: 486 CWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EF 538
CWET VGQEM KL I D + +A L +DF R L V Y S CW + EF
Sbjct: 499 CWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSD---YWCWDLESKFPEYGEF 555
Query: 539 AIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASN 598
I +NVL +VY Q + W+GAFFSP LPA LK I + Y++ W++L P + FRAS
Sbjct: 556 KIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASR 615
Query: 599 SNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST-FPSSLQS 657
SN F+L +LL L L ++P +I R S CGPF+ ++++ +T+ FP S
Sbjct: 616 SNNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGS 675
Query: 658 FIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQL-SLESRDK 707
+ ++S +P +++ ++++Y ++A + K QL+ Q+ + S DK
Sbjct: 676 VVGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDK 726
Score = 127 bits (320), Expect = 3e-29
Identities = 97/373 (26%), Positives = 166/373 (44%), Gaps = 33/373 (8%)
Query: 101 RRLRDIQETQMKYLSEWDQWKRYSSKS---WKRFLEKAREMTTHLELWREDIRSIEGKFG 157
R LR + +K+ + + Y + W++F A W I+ IE FG
Sbjct: 76 RALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIFIPWEMRIKKIESHFG 135
Query: 158 TGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYP 217
+G+ SYF FLR+L +N+V+ ++ +++P L+ +++ IP + + +
Sbjct: 136 SGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARKTIPKEQVSSAQDLDT 195
Query: 218 VSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLA 277
V S G G+L+ + LFYG+Y + K Y LPLAY L +A A
Sbjct: 196 VWSLG---------------GYLQYSVLFYGYYGRER-KIGRAGYRLPLAYFLVGMAVFA 239
Query: 278 LSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRAD 337
S + ++K+ + + +L + ++C ++F WD+ I N A+ K +++ +R
Sbjct: 240 YSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREA 299
Query: 338 LEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQ--EHMKKEI 395
+ EE+ ++K S+ LR+ N +VL L Y IY SQ E KKE+
Sbjct: 300 ILEEQEKKK-----SKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKEL 354
Query: 396 DKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATI 455
E S+V++L I P F I E Y P +R + R + + L +
Sbjct: 355 TLWEKNE-------VSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVLYLGNL 407
Query: 456 CVLVFTLGSKITS 468
L+ L K+ S
Sbjct: 408 YSLIIALLDKVNS 420
>gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo
sapiens]
Length = 754
Score = 38.1 bits (87), Expect = 0.029
Identities = 44/185 (23%), Positives = 76/185 (41%), Gaps = 30/185 (16%)
Query: 412 IVITLANFITPMIFAKII-RYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD 470
+ + L ++T F I+ + + PG IL C++M I V+ F
Sbjct: 508 VSVLLLTYLTLEKFLVIVFPFSNIRPGKRQTSVILICIWMAGFLIAVIPFWN-------K 560
Query: 471 DDTCDLCGYNQKLYPCWETQ---VGQEMYKLMIFDFIIILA--------VTLFVDFPRKL 519
D + G N +P + Q +G + Y L IF + +LA +T+F +
Sbjct: 561 DYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYITMFCSIQKTA 620
Query: 520 LVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAI------ATLKFI 573
L T ++ C+G+ E A+ + IV+ ICWI F +L +I
Sbjct: 621 LQT----TEVRNCFGR-EVAVANRFFFIVFSDAICWIPVFVVKILSLFRVEIPDTMTSWI 675
Query: 574 IIFYV 578
+IF++
Sbjct: 676 VIFFL 680
>gi|83700231 cytotoxic T-lymphocyte-associated protein 4 isoform b
precursor [Homo sapiens]
Length = 174
Score = 33.5 bits (75), Expect = 0.71
Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 410 PSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSC 469
P++V+ + I + Y E+R+T+LR ++ +C + +G+++T
Sbjct: 43 PAVVLASSRGIASFV----CEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFL 98
Query: 470 DDDTC 474
DD C
Sbjct: 99 DDSIC 103
>gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform a
precursor [Homo sapiens]
Length = 223
Score = 33.5 bits (75), Expect = 0.71
Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 410 PSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSC 469
P++V+ + I + Y E+R+T+LR ++ +C + +G+++T
Sbjct: 43 PAVVLASSRGIASFV----CEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFL 98
Query: 470 DDDTC 474
DD C
Sbjct: 99 DDSIC 103
>gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]
Length = 778
Score = 33.1 bits (74), Expect = 0.93
Identities = 23/106 (21%), Positives = 48/106 (45%), Gaps = 12/106 (11%)
Query: 43 LPSYRSIARRRTTVHSRDKQSGTLLKPTDSYSSQLEDRIAENLSSHSLR-NYALNISEKR 101
LP R RR++ H +K TL PT S L+ + SH + +Y + +++K
Sbjct: 240 LPGSRGPRRRKSKQHFVEKNKLTLGLPTPKTDSYLQLHNKKRGESHPEQISYPVRVTDKT 299
Query: 102 RLRDIQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWRE 147
+++ +E + + D+W ++A+++ + E W +
Sbjct: 300 SIQNAKEMENAAIDPEDKWH-----------QRAQQLKNYQEHWSQ 334
>gi|106067657 luteinizing hormone/choriogonadotropin receptor
precursor [Homo sapiens]
Length = 699
Score = 32.0 bits (71), Expect = 2.1
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 164 FSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVY-----PV 218
+ FLR L+ L ++ ++ M VL +L ++YK+T F++ D +Y V
Sbjct: 359 YDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASV 418
Query: 219 SSSGLIYFYSYIIDLLSGTG 238
S +Y++ ID +G+G
Sbjct: 419 DSQTKGQYYNHAIDWQTGSG 438
>gi|153945816 Nanog homeobox [Homo sapiens]
Length = 305
Score = 30.4 bits (67), Expect = 6.0
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 7 SALQPGRPSRQPAVHPENLSLDSSCFSSPPVNFLQELPSYRSIARRRTTVHSRDKQSGTL 66
SA P + P +L + S SS Q + +S+A++ V + +++ T+
Sbjct: 42 SAEMPHTETVSPLPSSMDLLIQDSPDSSTSPKGKQPTSAEKSVAKKEDKVPVKKQKTRTV 101
Query: 67 LKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQWKRYSSK 126
T L DR R L++ + + L +I K + W Q +R SK
Sbjct: 102 FSSTQL--CVLNDRFQ--------RQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSK 151
Query: 127 SWKR 130
W++
Sbjct: 152 RWQK 155
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 30.4 bits (67), Expect = 6.0
Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 11/110 (10%)
Query: 60 DKQSGTLLKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQ 119
+K+ L + + +LED + +L S RN LN+ +++ + + E+Q K S+
Sbjct: 3225 EKEKAKLGRSEERDKEELED-LKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRML 3283
Query: 120 WKRYSSKSWKRFLE----------KAREMTTHLELWREDIRSIEGKFGTG 159
+ S+ R LE + REM++ L+ RE ++ GTG
Sbjct: 3284 YDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTG 3333
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 30.4 bits (67), Expect = 6.0
Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 11/110 (10%)
Query: 60 DKQSGTLLKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQ 119
+K+ L + + +LED + +L S RN LN+ +++ + + E+Q K S+
Sbjct: 3217 EKEKAKLGRSEERDKEELED-LKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRML 3275
Query: 120 WKRYSSKSWKRFLE----------KAREMTTHLELWREDIRSIEGKFGTG 159
+ S+ R LE + REM++ L+ RE ++ GTG
Sbjct: 3276 YDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTG 3325
>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
Length = 478
Score = 30.4 bits (67), Expect = 6.0
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 389 EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIF----AKIIRYEDYSPGFEIRLTI 444
E + K +D +F F++YL VI F P+IF AK ++YS F + +
Sbjct: 231 EKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMA 290
Query: 445 LRCVFMR 451
+F R
Sbjct: 291 FVDMFAR 297
>gi|90421313 cystic fibrosis transmembrane conductance regulator
[Homo sapiens]
Length = 1480
Score = 30.0 bits (66), Expect = 7.9
Identities = 43/204 (21%), Positives = 81/204 (39%), Gaps = 18/204 (8%)
Query: 84 NLSSHSLRNYALNISEKRRL--RDIQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTH 141
NL +HS+ N NI K R + L+E D + R S+ + +
Sbjct: 771 NLMTHSV-NQGQNIHRKTTASTRKVSLAPQANLTELDIYSRRLSQETGLEISEEINEEDL 829
Query: 142 LELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSF 201
E + +D+ SI + ++ ++LR++ + +IF++I+ LV+ + +
Sbjct: 830 KECFFDDMESIPA-----VTTWNTYLRYITVHKSLIFVLIWCLVIFLAEVAASLVVLWLL 884
Query: 202 VLIPFKD-------MDKQCTVYPVSSSGLIYFYSY--IIDLLSGTGFLEETSLFYGHYTI 252
P +D + V S+S FY Y + D L GF L + T+
Sbjct: 885 GNTPLQDKGNSTHSRNNSYAVIITSTSSYYVFYIYVGVADTLLAMGFFRGLPLVHTLITV 944
Query: 253 DGVKFQNFTYDLPLAYLLSTIASL 276
+ + + L +ST+ +L
Sbjct: 945 SKILHHKMLHSV-LQAPMSTLNTL 967
>gi|21536376 ATP-binding cassette, sub-family A member 1 [Homo
sapiens]
Length = 2261
Score = 30.0 bits (66), Expect = 7.9
Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 18/127 (14%)
Query: 552 TICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGL 611
+I W F S L+P + + +++ +K +LL P+ + F FL V +
Sbjct: 679 SILWFSWFISSLIPLLVSAGLLVVI-LKLGNLL--------PYSDPSVVFVFLSVFAVVT 729
Query: 612 CLAIIPLTISISRIPSSKACGPFTNFN--------TTW-EVIPKTVSTFPSSLQSFIHGV 662
L ++ SR + ACG F W + + T+ F S L G
Sbjct: 730 ILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGF 789
Query: 663 TSEAFAV 669
E FA+
Sbjct: 790 GCEYFAL 796
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.140 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,536,977
Number of Sequences: 37866
Number of extensions: 1097411
Number of successful extensions: 3971
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3878
Number of HSP's gapped (non-prelim): 40
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.