Guide to the Human Genome
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Search of human proteins with 23510360

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23510360 Ras association domain family 4 [Homo sapiens]
         (321 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23510360 Ras association domain family 4 [Homo sapiens]            647   0.0  
gi|25777677 Ras association domain family 2 [Homo sapiens]            350   1e-96
gi|7661964 Ras association domain family 2 [Homo sapiens]             350   1e-96
gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isofor...   196   2e-50
gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isofor...   196   2e-50
gi|30039698 Ras association (RalGDS/AF-6) domain family member 3...    64   2e-10
gi|25777684 Ras association domain family 1 isoform D [Homo sapi...    62   7e-10
gi|25777682 Ras association domain family 1 isoform C [Homo sapi...    62   7e-10
gi|20149588 Ras association domain family 1 isoform A [Homo sapi...    62   7e-10
gi|25777680 Ras association domain family 1 isoform B [Homo sapi...    62   7e-10
gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isofor...    61   2e-09
gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isofor...    61   2e-09
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora...    38   0.014
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora...    38   0.014
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora...    38   0.014
gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isofor...    37   0.031
gi|110815800 WD repeat domain 32 [Homo sapiens]                        35   0.089
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         34   0.15 
gi|18104959 thioredoxin domain containing 9 [Homo sapiens]             33   0.44 
gi|119943093 glycogenin 2 isoform a [Homo sapiens]                     32   0.58 
gi|119964690 glycogenin 2 isoform b [Homo sapiens]                     32   0.58 
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]                32   0.76 
gi|118918411 zinc finger protein 777 [Homo sapiens]                    32   0.76 
gi|188536004 zinc finger protein 469 [Homo sapiens]                    32   0.99 
gi|37622341 zinc finger protein 42 isoform 2 [Homo sapiens]            32   0.99 
gi|37622345 zinc finger protein 42 isoform 1 [Homo sapiens]            32   0.99 
gi|169214072 PREDICTED: zinc finger and SCAN domain containing 5...    31   1.3  
gi|169214427 PREDICTED: zinc finger and SCAN domain containing 5...    31   1.3  
gi|169213343 PREDICTED: zinc finger and SCAN domain containing 5...    31   1.3  
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1...    31   1.7  

>gi|23510360 Ras association domain family 4 [Homo sapiens]
          Length = 321

 Score =  647 bits (1668), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIA 60
           MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIA
Sbjct: 1   MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIA 60

Query: 61  WGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESS 120
           WGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESS
Sbjct: 61  WGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESS 120

Query: 121 TDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSV 180
           TDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSV
Sbjct: 121 TDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSV 180

Query: 181 FTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPL 240
           FTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPL
Sbjct: 181 FTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPL 240

Query: 241 ISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLT 300
           ISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLT
Sbjct: 241 ISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLT 300

Query: 301 MKFQALRLTMLQRLEQLVEAK 321
           MKFQALRLTMLQRLEQLVEAK
Sbjct: 301 MKFQALRLTMLQRLEQLVEAK 321


>gi|25777677 Ras association domain family 2 [Homo sapiens]
          Length = 326

 Score =  350 bits (898), Expect = 1e-96
 Identities = 188/330 (56%), Positives = 232/330 (70%), Gaps = 33/330 (10%)

Query: 8   SSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPI 67
           +S VP    K I K+ELL  LKTYN Y+EG++ QLRHREEE   I+EGLLNI+WGLRRPI
Sbjct: 7   TSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISWGLRRPI 66

Query: 68  RLQMQDDREQVHLP--STSWMPRRPSCPLKEPSPQNGNITAQGPSIQPV----------- 114
           RLQMQDD E++  P  S+SW      C          N+ AQG +++P+           
Sbjct: 67  RLQMQDDNERIRPPPSSSSW---HSGC----------NLGAQGTTLKPLTVPKVQISEVD 113

Query: 115 -----HKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSI 169
                 +  SSTDS G     E+ PQLMRT+SD     +RR   R P + +RIRRHRFSI
Sbjct: 114 APPEGDQMPSSTDSRGLKPLQEDTPQLMRTRSDVGV--RRRGNVRTPSDQRRIRRHRFSI 171

Query: 170 NGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGE 229
           NGHFYNHKTSVFTPAYGSVTNVR+NSTMTT QVL LLLNKF++E+   EFALY+VH SGE
Sbjct: 172 NGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGE 231

Query: 230 RTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLK 289
           + KLK  +YPLI+RIL GPCE+I+++FLME D   EV ++VAQYIKFEMPVL SF++KL+
Sbjct: 232 KQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQ 291

Query: 290 EEEEREIIKLTMKFQALRLTMLQRLEQLVE 319
           EEE+RE+ KL  K+  LRL + QRLE++ E
Sbjct: 292 EEEDREVKKLMRKYTVLRLMIRQRLEEIAE 321


>gi|7661964 Ras association domain family 2 [Homo sapiens]
          Length = 326

 Score =  350 bits (898), Expect = 1e-96
 Identities = 188/330 (56%), Positives = 232/330 (70%), Gaps = 33/330 (10%)

Query: 8   SSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPI 67
           +S VP    K I K+ELL  LKTYN Y+EG++ QLRHREEE   I+EGLLNI+WGLRRPI
Sbjct: 7   TSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISWGLRRPI 66

Query: 68  RLQMQDDREQVHLP--STSWMPRRPSCPLKEPSPQNGNITAQGPSIQPV----------- 114
           RLQMQDD E++  P  S+SW      C          N+ AQG +++P+           
Sbjct: 67  RLQMQDDNERIRPPPSSSSW---HSGC----------NLGAQGTTLKPLTVPKVQISEVD 113

Query: 115 -----HKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSI 169
                 +  SSTDS G     E+ PQLMRT+SD     +RR   R P + +RIRRHRFSI
Sbjct: 114 APPEGDQMPSSTDSRGLKPLQEDTPQLMRTRSDVGV--RRRGNVRTPSDQRRIRRHRFSI 171

Query: 170 NGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGE 229
           NGHFYNHKTSVFTPAYGSVTNVR+NSTMTT QVL LLLNKF++E+   EFALY+VH SGE
Sbjct: 172 NGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGE 231

Query: 230 RTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLK 289
           + KLK  +YPLI+RIL GPCE+I+++FLME D   EV ++VAQYIKFEMPVL SF++KL+
Sbjct: 232 KQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQ 291

Query: 290 EEEEREIIKLTMKFQALRLTMLQRLEQLVE 319
           EEE+RE+ KL  K+  LRL + QRLE++ E
Sbjct: 292 EEEDREVKKLMRKYTVLRLMIRQRLEEIAE 321


>gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isoform b
           [Homo sapiens]
          Length = 369

 Score =  196 bits (499), Expect = 2e-50
 Identities = 124/339 (36%), Positives = 197/339 (58%), Gaps = 42/339 (12%)

Query: 9   SHVPISDSKSIQKSELLGLLKTYNCYHEG-KSFQLRHRE-EEGTLIIEGLLNIAWGLRRP 66
           S + I++   I + +L  LLKTYN ++E  K+  + + E E+G LI+EG+L+I WG++RP
Sbjct: 42  SWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFWGVKRP 101

Query: 67  IRLQMQDDR--------EQVHLPSTSWMPR--------------RPSCPLKEP-SPQNGN 103
           I+L++QD++        +   + S+  M R              R   P+ E  + Q   
Sbjct: 102 IQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMSEKRNSQEDY 161

Query: 104 ITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQR-RPKCRAPGEAQRI 162
           ++    +++P  K E             ++P L RT S+A+ + +R +P      E Q+ 
Sbjct: 162 LSYHSNTLKPHAKDEP------------DSPVLYRTMSEAALVRKRMKPLMMDRKERQK- 208

Query: 163 RRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY 222
             +R SINGHFYNH+TS+F PA+ S T VRVNS M T +V+  LL KF++E+ P +FAL+
Sbjct: 209 --NRASINGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALH 266

Query: 223 IVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLD 282
           I+  +GE+ +LK  + PL+ R+L GP EK ARIFLM+ D   E+  +VAQYI F   +L+
Sbjct: 267 IIFATGEQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKD-AEEISSDVAQYINFHFSLLE 325

Query: 283 SFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK 321
           S +++L EEE+REI ++  KF   +  +L+ L+  +  K
Sbjct: 326 SILQRLNEEEKREIQRIVTKFNKEKAIILKCLQNKLVIK 364


>gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isoform a
           [Homo sapiens]
          Length = 337

 Score =  196 bits (499), Expect = 2e-50
 Identities = 124/339 (36%), Positives = 197/339 (58%), Gaps = 42/339 (12%)

Query: 9   SHVPISDSKSIQKSELLGLLKTYNCYHEG-KSFQLRHRE-EEGTLIIEGLLNIAWGLRRP 66
           S + I++   I + +L  LLKTYN ++E  K+  + + E E+G LI+EG+L+I WG++RP
Sbjct: 10  SWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFWGVKRP 69

Query: 67  IRLQMQDDR--------EQVHLPSTSWMPR--------------RPSCPLKEP-SPQNGN 103
           I+L++QD++        +   + S+  M R              R   P+ E  + Q   
Sbjct: 70  IQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMSEKRNSQEDY 129

Query: 104 ITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQR-RPKCRAPGEAQRI 162
           ++    +++P  K E             ++P L RT S+A+ + +R +P      E Q+ 
Sbjct: 130 LSYHSNTLKPHAKDEP------------DSPVLYRTMSEAALVRKRMKPLMMDRKERQK- 176

Query: 163 RRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY 222
             +R SINGHFYNH+TS+F PA+ S T VRVNS M T +V+  LL KF++E+ P +FAL+
Sbjct: 177 --NRASINGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALH 234

Query: 223 IVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLD 282
           I+  +GE+ +LK  + PL+ R+L GP EK ARIFLM+ D   E+  +VAQYI F   +L+
Sbjct: 235 IIFATGEQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKD-AEEISSDVAQYINFHFSLLE 293

Query: 283 SFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK 321
           S +++L EEE+REI ++  KF   +  +L+ L+  +  K
Sbjct: 294 SILQRLNEEEKREIQRIVTKFNKEKAIILKCLQNKLVIK 332


>gi|30039698 Ras association (RalGDS/AF-6) domain family member 3
           [Homo sapiens]
          Length = 238

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 11/135 (8%)

Query: 186 GSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY-IVHESGE--RTKLKDCEYPLIS 242
           G +  + ++ST T  +V+  LL KF V + P++FALY   H   +    KL D E+PL  
Sbjct: 108 GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYL 167

Query: 243 RILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMK 302
           R++ GP        L E        HE+ ++  F +P L +F+  L +EE+ ++  L  +
Sbjct: 168 RLVAGPRTDTLSFVLRE--------HEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRR 219

Query: 303 FQALRLTMLQRLEQL 317
           + A R  + + L ++
Sbjct: 220 YTAYRQKLEEALREV 234


>gi|25777684 Ras association domain family 1 isoform D [Homo
           sapiens]
          Length = 344

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 53/173 (30%), Positives = 78/173 (45%), Gaps = 32/173 (18%)

Query: 154 RAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVE 213
           R PG    +RR            +TS + P   +V ++ V S     +V+  LL KF V 
Sbjct: 194 RGPGRGTSVRR------------RTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVV 240

Query: 214 DGPSEFALYIVHESGER------TKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVP 267
           D P +FAL+   E  ER       KL D E PL  R+L GP +K     L E D G    
Sbjct: 241 DDPRKFALF---ERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSG---- 293

Query: 268 HEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEA 320
                +  F MP L +F+  L+ EEE  + ++  K+   R    Q++++ + A
Sbjct: 294 --EVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCR----QKIQEALHA 340


>gi|25777682 Ras association domain family 1 isoform C [Homo
           sapiens]
          Length = 270

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 53/173 (30%), Positives = 78/173 (45%), Gaps = 32/173 (18%)

Query: 154 RAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVE 213
           R PG    +RR            +TS + P   +V ++ V S     +V+  LL KF V 
Sbjct: 120 RGPGRGTSVRR------------RTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVV 166

Query: 214 DGPSEFALYIVHESGER------TKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVP 267
           D P +FAL+   E  ER       KL D E PL  R+L GP +K     L E D G    
Sbjct: 167 DDPRKFALF---ERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSG---- 219

Query: 268 HEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEA 320
                +  F MP L +F+  L+ EEE  + ++  K+   R    Q++++ + A
Sbjct: 220 --EVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCR----QKIQEALHA 266


>gi|20149588 Ras association domain family 1 isoform A [Homo
           sapiens]
          Length = 340

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 53/173 (30%), Positives = 78/173 (45%), Gaps = 32/173 (18%)

Query: 154 RAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVE 213
           R PG    +RR            +TS + P   +V ++ V S     +V+  LL KF V 
Sbjct: 190 RGPGRGTSVRR------------RTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVV 236

Query: 214 DGPSEFALYIVHESGER------TKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVP 267
           D P +FAL+   E  ER       KL D E PL  R+L GP +K     L E D G    
Sbjct: 237 DDPRKFALF---ERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSG---- 289

Query: 268 HEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEA 320
                +  F MP L +F+  L+ EEE  + ++  K+   R    Q++++ + A
Sbjct: 290 --EVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCR----QKIQEALHA 336


>gi|25777680 Ras association domain family 1 isoform B [Homo
           sapiens]
          Length = 189

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 53/173 (30%), Positives = 78/173 (45%), Gaps = 32/173 (18%)

Query: 154 RAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVE 213
           R PG    +RR            +TS + P   +V ++ V S     +V+  LL KF V 
Sbjct: 39  RGPGRGTSVRR------------RTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVV 85

Query: 214 DGPSEFALYIVHESGER------TKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVP 267
           D P +FAL+   E  ER       KL D E PL  R+L GP +K     L E D G    
Sbjct: 86  DDPRKFALF---ERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSG---- 138

Query: 268 HEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEA 320
                +  F MP L +F+  L+ EEE  + ++  K+   R    Q++++ + A
Sbjct: 139 --EVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCR----QKIQEALHA 185


>gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isoform C
           [Homo sapiens]
          Length = 265

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 14/143 (9%)

Query: 177 KTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY-IVHESGE--RTKL 233
           +TS + P   ++  + ++ST T  +V+  LL KF V D P +FAL+  +H+ G+    KL
Sbjct: 124 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKL 182

Query: 234 KDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEE 293
              + PL  R+L GP  ++    L E + G        ++  F +P L +F+  L++EE+
Sbjct: 183 SIADRPLYLRLLAGPDTEVLSFVLKENETG------EVEWDAFSIPELQNFLTILEKEEQ 236

Query: 294 REIIKLTMKFQALRLTMLQRLEQ 316
            +I ++  K+   R    Q+LE+
Sbjct: 237 DKIQQVQKKYDKFR----QKLEE 255


>gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isoform A
           [Homo sapiens]
          Length = 418

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 14/143 (9%)

Query: 177 KTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY-IVHESGE--RTKL 233
           +TS + P   ++  + ++ST T  +V+  LL KF V D P +FAL+  +H+ G+    KL
Sbjct: 277 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKL 335

Query: 234 KDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEE 293
              + PL  R+L GP  ++    L E + G        ++  F +P L +F+  L++EE+
Sbjct: 336 SIADRPLYLRLLAGPDTEVLSFVLKENETG------EVEWDAFSIPELQNFLTILEKEEQ 389

Query: 294 REIIKLTMKFQALRLTMLQRLEQ 316
            +I ++  K+   R    Q+LE+
Sbjct: 390 DKIQQVQKKYDKFR----QKLEE 408


>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 1 [Homo
           sapiens]
          Length = 1834

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 191 VRVNSTMTTLQVLTLLLNKFRVED---GPSEFALYIVHESGERTKLKDCEYPLISRILHG 247
           +RV+ST TT  V+  L  KFR +       +++LY VH SGER +L   E PL+ ++   
Sbjct: 60  IRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGER-RLDIDEKPLVVQLNWN 118

Query: 248 PCEKIARIFLMEADLGVEVPHEVAQYIKFEMP-VLDSFVEKLKEEEEREIIKLTMKFQAL 306
             ++  R  L   +  +    +     K E   V+ +F   L ++E++E  K   + +AL
Sbjct: 119 KDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKE--KKKREKEAL 176

Query: 307 R 307
           R
Sbjct: 177 R 177


>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 2 [Homo
           sapiens]
          Length = 1651

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 38/124 (30%), Positives = 62/124 (50%), Gaps = 12/124 (9%)

Query: 191 VRVNSTMTTLQVLTLLLNKFRVED---GPSEFALYIVHESGERTKLKDCEYPLISRILHG 247
           +RV+ST TT  V+  L  KFR +       +++LY VH SGER +L   E PL+ ++   
Sbjct: 60  IRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGER-RLDIDEKPLVVQLNWN 118

Query: 248 PCEKIARIFLMEADLGVEVPHEVAQYIKFEMP----VLDSFVEKLKEEEEREIIKLTMKF 303
             ++  R  L   +    +P + AQ    E      V+ +F   L ++E++E  K   + 
Sbjct: 119 KDDREGRFVLKNEN--DAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKE--KKKREK 174

Query: 304 QALR 307
           +ALR
Sbjct: 175 EALR 178


>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 3 [Homo
           sapiens]
          Length = 1612

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 191 VRVNSTMTTLQVLTLLLNKFRVED---GPSEFALYIVHESGERTKLKDCEYPLISRILHG 247
           +RV+ST TT  V+  L  KFR +       +++LY VH SGER +L   E PL+ ++   
Sbjct: 60  IRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGER-RLDIDEKPLVVQLNWN 118

Query: 248 PCEKIARIFLMEADLGVEVPHEVAQYIKFEMP-VLDSFVEKLKEEEEREIIKLTMKFQAL 306
             ++  R  L   +  +    +     K E   V+ +F   L ++E++E  K   + +AL
Sbjct: 119 KDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKE--KKKREKEAL 176

Query: 307 R 307
           R
Sbjct: 177 R 177


>gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isoform B
           [Homo sapiens]
          Length = 336

 Score = 36.6 bits (83), Expect = 0.031
 Identities = 19/54 (35%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 177 KTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY-IVHESGE 229
           +TS + P   ++  + ++ST T  +V+  LL KF V D P +FAL+  +H+ G+
Sbjct: 277 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQ 329


>gi|110815800 WD repeat domain 32 [Homo sapiens]
          Length = 559

 Score = 35.0 bits (79), Expect = 0.089
 Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 8/75 (10%)

Query: 76  EQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQ 135
           +  H P  +  PRRP  P   P+P++G +   G        A  S+ +S P E +  +P 
Sbjct: 43  DATHPPPPARSPRRPGAPSLSPAPRSGELGLPG--------APESSTASAPGEPSPPSPP 94

Query: 136 LMRTKSDASCMSQRR 150
             R   D    S+ R
Sbjct: 95  CRRPGPDCRAKSRGR 109


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 5/80 (6%)

Query: 90  PSCPLKEPSPQNGNITA---QGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCM 146
           PS  +KEPS Q    T+   + P  +P+ + +  +      +E E+  +  R +S +   
Sbjct: 226 PSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK--EKTRPRSRSRSK 283

Query: 147 SQRRPKCRAPGEAQRIRRHR 166
           S+ R + R+P   +  RRHR
Sbjct: 284 SRSRTRSRSPSHTRPRRRHR 303


>gi|18104959 thioredoxin domain containing 9 [Homo sapiens]
          Length = 226

 Score = 32.7 bits (73), Expect = 0.44
 Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query: 258 MEADLGVEV-----PHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMK-FQALRLTML 311
           MEAD  V++      H++ Q  K     LDS ++KL + +E E+ +L  K  QALR    
Sbjct: 1   MEADASVDMFSKVLEHQLLQTTKLVEEHLDSEIQKLDQMDEDELERLKEKRLQALRKAQQ 60

Query: 312 QRLEQL 317
           Q+ E L
Sbjct: 61  QKQEWL 66


>gi|119943093 glycogenin 2 isoform a [Homo sapiens]
          Length = 470

 Score = 32.3 bits (72), Expect = 0.58
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 12/88 (13%)

Query: 48  EGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSC-PLKEPSPQNGNITA 106
           E T I++  L++  G R           + +  P T   P   +C PL +PSPQ  + T 
Sbjct: 327 EPTQIVDETLSLPEGRR---------SEDMIACPETE-TPAVITCDPLSQPSPQPADFTE 376

Query: 107 QGPSIQPVHKAESSTDSSGPLEEAEEAP 134
               +QP +K E S  S    E ++E P
Sbjct: 377 TETILQPANKVE-SVSSEETFEPSQELP 403


>gi|119964690 glycogenin 2 isoform b [Homo sapiens]
          Length = 501

 Score = 32.3 bits (72), Expect = 0.58
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 12/88 (13%)

Query: 48  EGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSC-PLKEPSPQNGNITA 106
           E T I++  L++  G R           + +  P T   P   +C PL +PSPQ  + T 
Sbjct: 358 EPTQIVDETLSLPEGRR---------SEDMIACPETE-TPAVITCDPLSQPSPQPADFTE 407

Query: 107 QGPSIQPVHKAESSTDSSGPLEEAEEAP 134
               +QP +K E S  S    E ++E P
Sbjct: 408 TETILQPANKVE-SVSSEETFEPSQELP 434


>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
          Length = 1103

 Score = 32.0 bits (71), Expect = 0.76
 Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 22/149 (14%)

Query: 40   FQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSP 99
            F+LR R++    +IE  +  A      ++ Q Q   +    P T   P  PS    + +P
Sbjct: 940  FKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQV-LQSTQSPRTKNAPSLPSRTCYKTAP 998

Query: 100  QNGNI---------TAQGPSIQPVHKAESSTDSSGP-------LEEAEEAPQLMRTKSDA 143
              G I         T +GPS+QP    E +  +  P       +E+ E      R + D 
Sbjct: 999  --GKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDD 1056

Query: 144  SCMSQRRPKCRAPG---EAQRIRRHRFSI 169
            S  + +   C+      EA R+ R + ++
Sbjct: 1057 SSYTSKLLSCKVTSEVLEATRVNRRKSAL 1085


>gi|118918411 zinc finger protein 777 [Homo sapiens]
          Length = 831

 Score = 32.0 bits (71), Expect = 0.76
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 2/79 (2%)

Query: 80  LPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPL--EEAEEAPQLM 137
           +P    +P+  S P +E S +  ++  +GPS+     +E  T   GPL  +E  + P   
Sbjct: 50  IPRQGSLPQTSSAPKQETSGRMPHVLQKGPSLLCSAASEQETSLQGPLASQEGTQYPPPA 109

Query: 138 RTKSDASCMSQRRPKCRAP 156
             + + S +S       AP
Sbjct: 110 AAEQEVSLLSHSPHHQEAP 128


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 31.6 bits (70), Expect = 0.99
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 11/78 (14%)

Query: 83   TSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSD 142
            T+  P +PS P + P+P+     AQ  S            + GP E  E+ P       +
Sbjct: 3733 TATTPAKPSFPSRSPAPERLPARAQAKSC-----------TKGPREAGEQGPHGSLGPKE 3781

Query: 143  ASCMSQRRPKCRAPGEAQ 160
                S +R K + PG A+
Sbjct: 3782 KGESSTKRKKGQVPGPAR 3799


>gi|37622341 zinc finger protein 42 isoform 2 [Homo sapiens]
          Length = 734

 Score = 31.6 bits (70), Expect = 0.99
 Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 16/151 (10%)

Query: 47  EEGTLIIEGLLNIAWGLRRPIRLQMQDDR---EQVHLPSTSWMPRRPSCPLKEPSPQNGN 103
           EE   +++GL     G RR + +Q+Q      E++   S   +P     P  EP P+   
Sbjct: 113 EEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEKMEPSSFQPLPETEP-PTPEPGPKTPP 171

Query: 104 ITAQGP--SIQPVHKAESSTDS----SGPLEEAEEAPQLMRTKSDASC---MSQRRPKCR 154
            T Q     +Q   ++E + DS    SGPL   +E+   +  +    C   + Q  P  +
Sbjct: 172 RTMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSK 231

Query: 155 APGEAQRIRRHRFSINGHFYNHKTSVFTPAY 185
              E    R H  ++   ++     +F+P +
Sbjct: 232 TGPEGPSWREHPRAL---WHEEAGGIFSPGF 259


>gi|37622345 zinc finger protein 42 isoform 1 [Homo sapiens]
          Length = 734

 Score = 31.6 bits (70), Expect = 0.99
 Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 16/151 (10%)

Query: 47  EEGTLIIEGLLNIAWGLRRPIRLQMQDDR---EQVHLPSTSWMPRRPSCPLKEPSPQNGN 103
           EE   +++GL     G RR + +Q+Q      E++   S   +P     P  EP P+   
Sbjct: 113 EEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEKMEPSSFQPLPETEP-PTPEPGPKTPP 171

Query: 104 ITAQGP--SIQPVHKAESSTDS----SGPLEEAEEAPQLMRTKSDASC---MSQRRPKCR 154
            T Q     +Q   ++E + DS    SGPL   +E+   +  +    C   + Q  P  +
Sbjct: 172 RTMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSK 231

Query: 155 APGEAQRIRRHRFSINGHFYNHKTSVFTPAY 185
              E    R H  ++   ++     +F+P +
Sbjct: 232 TGPEGPSWREHPRAL---WHEEAGGIFSPGF 259


>gi|169214072 PREDICTED: zinc finger and SCAN domain containing 5C
           [Homo sapiens]
          Length = 495

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 20/107 (18%)

Query: 71  MQDDREQVHLPSTSWMPRRPSCPL-------KEPSPQNG--NITAQGPSIQPVHKAESST 121
           +++DRE+ +   TS  P+ P+ P        KEP  +    N+ A  PS   V + E+ST
Sbjct: 225 LEEDREE-NPGLTSPEPQLPNSPSVVGAKEGKEPKKRASVENVDADTPSACVVER-EAST 282

Query: 122 DSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRA--------PGEAQ 160
            S G   +A     L R+K DA+ +SQ  P+  A        PG+A+
Sbjct: 283 HS-GSRGDALNLRGLKRSKPDATSISQEEPQGEATPVGNRESPGQAE 328


>gi|169214427 PREDICTED: zinc finger and SCAN domain containing 5C
           [Homo sapiens]
          Length = 495

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 20/107 (18%)

Query: 71  MQDDREQVHLPSTSWMPRRPSCPL-------KEPSPQNG--NITAQGPSIQPVHKAESST 121
           +++DRE+ +   TS  P+ P+ P        KEP  +    N+ A  PS   V + E+ST
Sbjct: 225 LEEDREE-NPGLTSPEPQLPNSPSVVGAKEGKEPKKRASVENVDADTPSACVVER-EAST 282

Query: 122 DSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRA--------PGEAQ 160
            S G   +A     L R+K DA+ +SQ  P+  A        PG+A+
Sbjct: 283 HS-GSRGDALNLRGLKRSKPDATSISQEEPQGEATPVGNRESPGQAE 328


>gi|169213343 PREDICTED: zinc finger and SCAN domain containing 5C
           [Homo sapiens]
          Length = 496

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 21/108 (19%)

Query: 71  MQDDREQVHLPSTSWMPRRPSCPL--------KEPSPQNG--NITAQGPSIQPVHKAESS 120
           +++DRE+ +   TS  P+ P+ P         KEP  +    N+ A  PS   V + E+S
Sbjct: 225 LEEDREE-NPGLTSPEPQLPNSPTGVVGAKEGKEPQKRASVENVDADTPSACVVER-EAS 282

Query: 121 TDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRA--------PGEAQ 160
           T S G   +A     L R+K DA+ +SQ  P+  A        PG+A+
Sbjct: 283 THS-GSRGDALNLRGLKRSKPDATSISQEEPQGEATPVGNRESPGQAE 329


>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
            [Homo sapiens]
          Length = 1849

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 29/106 (27%), Positives = 40/106 (37%), Gaps = 22/106 (20%)

Query: 72   QDDREQVHLPSTSWMPRRP----------SCPLKEPSPQNGNITAQGPSIQPVHKAESST 121
            +D  EQ+  P  S  PR P          S P +   P N    AQGP   P   + SS 
Sbjct: 1135 EDSAEQLSSPMPSATPREPENHFVGGAEASAPGEAGRPLNSTSKAQGPESSPAVPSASS- 1193

Query: 122  DSSGP-----------LEEAEEAPQLMRTKSDASCMSQRRPKCRAP 156
             ++GP           L+ +      +  +  A   SQ+ PK  AP
Sbjct: 1194 GTAGPGNYVHPLTGRLLDPSSPLALALSARDRAMKESQQGPKGEAP 1239


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,749,367
Number of Sequences: 37866
Number of extensions: 600196
Number of successful extensions: 2517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 2437
Number of HSP's gapped (non-prelim): 122
length of query: 321
length of database: 18,247,518
effective HSP length: 102
effective length of query: 219
effective length of database: 14,385,186
effective search space: 3150355734
effective search space used: 3150355734
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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