BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo sapiens] (985 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo sa... 1959 0.0 gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo sa... 1775 0.0 gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo ... 209 1e-53 gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo ... 209 1e-53 gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens] 67 8e-11 gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens] 63 1e-09 gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens] 59 3e-08 gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens] 51 6e-06 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 50 1e-05 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 46 2e-04 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 46 2e-04 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 2e-04 gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 46 2e-04 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 44 7e-04 gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 44 0.001 gi|210032580 SET domain containing 1B [Homo sapiens] 43 0.002 gi|156104908 myosin heavy chain 6 [Homo sapiens] 42 0.002 gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 42 0.003 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 41 0.005 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 41 0.005 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 41 0.005 gi|109255234 centrosomal protein 290kDa [Homo sapiens] 41 0.005 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 41 0.005 gi|87299628 biorientation of chromosomes in cell division 1-like... 41 0.006 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.008 gi|38044112 restin isoform b [Homo sapiens] 40 0.011 gi|4506751 restin isoform a [Homo sapiens] 40 0.011 gi|20070262 TNF receptor-associated factor 3 interacting protein... 40 0.011 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.011 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.011 >gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo sapiens] Length = 985 Score = 1959 bits (5074), Expect = 0.0 Identities = 985/985 (100%), Positives = 985/985 (100%) Query: 1 MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLP 60 MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLP Sbjct: 1 MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLP 60 Query: 61 LQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRN 120 LQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRN Sbjct: 61 LQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRN 120 Query: 121 DANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHN 180 DANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHN Sbjct: 121 DANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHN 180 Query: 181 KEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRR 240 KEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRR Sbjct: 181 KEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRR 240 Query: 241 LRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDF 300 LRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDF Sbjct: 241 LRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDF 300 Query: 301 TKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILR 360 TKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILR Sbjct: 301 TKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILR 360 Query: 361 GHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPL 420 GHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPL Sbjct: 361 GHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPL 420 Query: 421 ITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKK 480 ITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKK Sbjct: 421 ITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKK 480 Query: 481 YIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLE 540 YIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLE Sbjct: 481 YIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLE 540 Query: 541 HSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQ 600 HSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQ Sbjct: 541 HSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQ 600 Query: 601 NLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQSSGCYS 660 NLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQSSGCYS Sbjct: 601 NLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQSSGCYS 660 Query: 661 LSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYL 720 LSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYL Sbjct: 661 LSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYL 720 Query: 721 KYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINI 780 KYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINI Sbjct: 721 KYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINI 780 Query: 781 FNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDNDLRT 840 FNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDNDLRT Sbjct: 781 FNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDNDLRT 840 Query: 841 TSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKL 900 TSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKL Sbjct: 841 TSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKL 900 Query: 901 KTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHV 960 KTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHV Sbjct: 901 KTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHV 960 Query: 961 IKTKREDIRELILKLHLQQQKGSSS 985 IKTKREDIRELILKLHLQQQKGSSS Sbjct: 961 IKTKREDIRELILKLHLQQQKGSSS 985 >gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo sapiens] Length = 1050 Score = 1775 bits (4598), Expect = 0.0 Identities = 924/1051 (87%), Positives = 942/1051 (89%), Gaps = 67/1051 (6%) Query: 1 MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSER---- 56 MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSER Sbjct: 1 MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLP 60 Query: 57 ---------------------------------------------WT-LPLQWERSLRNK 70 WT L ++ ++L Sbjct: 61 LQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRN 120 Query: 71 VISLDHKNKKHIRGCPVTSKSS----------------PERQLKVMLTNVLWTDLGRKFR 114 +L NK P TS S ER +V+LTNVL T+LGRK+ Sbjct: 121 DANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERIPRVILTNVLGTELGRKYI 180 Query: 115 KTLPRNDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSA 174 +T P + +L D + +QS+ L S+S SLE+ Q L P +S LSERGSQRSKTVDDNSA Sbjct: 181 RTPPVTEGSLSDTDNLQSEQLSSSSDGSLESYQNLNP-HKSCYLSERGSQRSKTVDDNSA 239 Query: 175 KQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLIS 234 KQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLIS Sbjct: 240 KQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLIS 299 Query: 235 RKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTK 294 RKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTK Sbjct: 300 RKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTK 359 Query: 295 PTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTI 354 PTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTI Sbjct: 360 PTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTI 419 Query: 355 EKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESA 414 EKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESA Sbjct: 420 EKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESA 479 Query: 415 LLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGC 474 LLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGC Sbjct: 480 LLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGC 539 Query: 475 VTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQE 534 VTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQE Sbjct: 540 VTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQE 599 Query: 535 IQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQ 594 IQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQ Sbjct: 600 IQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQ 659 Query: 595 AFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQ 654 AFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQ Sbjct: 660 AFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQ 719 Query: 655 SSGCYSLSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDV 714 SSGCYSLSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDV Sbjct: 720 SSGCYSLSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDV 779 Query: 715 IIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTW 774 IIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTW Sbjct: 780 IIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTW 839 Query: 775 TRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTI 834 TRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTI Sbjct: 840 TRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTI 899 Query: 835 DNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEV 894 DNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEV Sbjct: 900 DNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEV 959 Query: 895 EWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEK 954 EWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEK Sbjct: 960 EWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEK 1019 Query: 955 WFPRHVIKTKREDIRELILKLHLQQQKGSSS 985 WFPRHVIKTKREDIRELILKLHLQQQKGSSS Sbjct: 1020 WFPRHVIKTKREDIRELILKLHLQQQKGSSS 1050 >gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo sapiens] Length = 1105 Score = 209 bits (532), Expect = 1e-53 Identities = 207/731 (28%), Positives = 317/731 (43%), Gaps = 142/731 (19%) Query: 262 KKQEDDSTISTEFE-KPSENYHQDPKLPEEITTKPTKSDFTKLSSLNS---QELTLSNAT 317 K +E +S + E + K + H P + +K T L L Q +TL+ +T Sbjct: 182 KTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNEST 241 Query: 318 ---------------KSASAGSTTETVENSNSIDIVGISSLVEKDENE---LNTIEKPIL 359 KS + G TT+ +N ++ V I +V D+++ L T K IL Sbjct: 242 GPLLRTSIHQNSGGQKSQNTGLTTKKFYGNN-VEKVPIDIIVNCDDSKHTYLQTNGKVIL 300 Query: 360 RGHN--------EGNQSLISA-EPIVVSSDEEG--------------PVEHKSSEILKLQ 396 G E SL +PI++SSD++ P + S Sbjct: 301 PGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPST 360 Query: 397 SKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMEN--------------- 441 K + NEN +E L +P E ++++ P M++ Sbjct: 361 GKVEA-ALNENTCRAERELRSIP----EDSELNTVTLPRKARMKDQFGNSIINTPLKRRK 415 Query: 442 ISSIMPSNEMDLQLDFIFTSVY-------IGKIKGASKGCVTITKKYIKIPF-QVSLNEI 493 + S P + + L F SV +G + V +IKI + + + Sbjct: 416 VFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPV 475 Query: 494 SLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLEHS----------- 542 ++++T+ L +K + + R ++F Q++ QL+ + Sbjct: 476 EIILNTSDL-------TKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKG 528 Query: 543 VLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQNL 602 V + ++I L N + + + I+ EI I + + F F + Sbjct: 529 VNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNN----------ISNF--FAKI 576 Query: 603 SSKESSFIHYYCVSTCSFPA-GVAVAEEMKLKSVSQPSNTDA-AKPTYTFLQKQSSGCYS 660 +E++ C T G +E K+K+VS S +K + F Sbjct: 577 PFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFD-------- 628 Query: 661 LSITSNPDEEWREVRHT---GLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIID 717 +EE HT G V+KLIVYPPPP KGG+ VTNEDL CL EGEFLNDVIID Sbjct: 629 -------EEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIID 681 Query: 718 FYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRH 777 FYLKYL+LEK E +R HIFSSFFYK L ++E + NLS+ Q+RH RV+TWTRH Sbjct: 682 FYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERR-NHETTNLSIQQKRHGRVKTWTRH 740 Query: 778 INIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDN- 836 ++IF KD+IFVP+NE++HW+LAV+CFP LE+ YE P ++N I Sbjct: 741 VDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPH-----------YHENAVIQKC 789 Query: 837 DLRTTSTLSLSAEDSQSTESNMS----VPKKMCKRPCILILDSLKAASVQNTVQNLREYL 892 S +S SA + +S N S + K + K+ CI ++DS ++ + R Sbjct: 790 STVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDS-NPGQEESDPRYKRNIC 848 Query: 893 EVEWEVKLKTH 903 V++ VK H Sbjct: 849 SVKYSVKKINH 859 Score = 149 bits (376), Expect = 1e-35 Identities = 75/135 (55%), Positives = 99/135 (73%), Gaps = 1/135 (0%) Query: 848 AEDSQSTE-SNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQF 906 A+D+ S+E + +CK+PCIL++DSL+ S N V+ LREYLEVEWEVK + R F Sbjct: 943 ADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSF 1002 Query: 907 SKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHVIKTKRE 966 SK M PKVP+Q+N SDCGVY+LQYVESFF++PI++FELP++L WFP ++TKRE Sbjct: 1003 SKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKRE 1062 Query: 967 DIRELILKLHLQQQK 981 +IR +ILKL Q K Sbjct: 1063 EIRNIILKLQEDQSK 1077 >gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo sapiens] Length = 1112 Score = 209 bits (532), Expect = 1e-53 Identities = 207/731 (28%), Positives = 317/731 (43%), Gaps = 142/731 (19%) Query: 262 KKQEDDSTISTEFE-KPSENYHQDPKLPEEITTKPTKSDFTKLSSLNS---QELTLSNAT 317 K +E +S + E + K + H P + +K T L L Q +TL+ +T Sbjct: 189 KTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNEST 248 Query: 318 ---------------KSASAGSTTETVENSNSIDIVGISSLVEKDENE---LNTIEKPIL 359 KS + G TT+ +N ++ V I +V D+++ L T K IL Sbjct: 249 GPLLRTSIHQNSGGQKSQNTGLTTKKFYGNN-VEKVPIDIIVNCDDSKHTYLQTNGKVIL 307 Query: 360 RGHN--------EGNQSLISA-EPIVVSSDEEG--------------PVEHKSSEILKLQ 396 G E SL +PI++SSD++ P + S Sbjct: 308 PGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPST 367 Query: 397 SKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMEN--------------- 441 K + NEN +E L +P E ++++ P M++ Sbjct: 368 GKVEA-ALNENTCRAERELRSIP----EDSELNTVTLPRKARMKDQFGNSIINTPLKRRK 422 Query: 442 ISSIMPSNEMDLQLDFIFTSVY-------IGKIKGASKGCVTITKKYIKIPF-QVSLNEI 493 + S P + + L F SV +G + V +IKI + + + Sbjct: 423 VFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPV 482 Query: 494 SLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLEHS----------- 542 ++++T+ L +K + + R ++F Q++ QL+ + Sbjct: 483 EIILNTSDL-------TKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKG 535 Query: 543 VLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQNL 602 V + ++I L N + + + I+ EI I + + F F + Sbjct: 536 VNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNN----------ISNF--FAKI 583 Query: 603 SSKESSFIHYYCVSTCSFPA-GVAVAEEMKLKSVSQPSNTDA-AKPTYTFLQKQSSGCYS 660 +E++ C T G +E K+K+VS S +K + F Sbjct: 584 PFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFD-------- 635 Query: 661 LSITSNPDEEWREVRHT---GLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIID 717 +EE HT G V+KLIVYPPPP KGG+ VTNEDL CL EGEFLNDVIID Sbjct: 636 -------EEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIID 688 Query: 718 FYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRH 777 FYLKYL+LEK E +R HIFSSFFYK L ++E + NLS+ Q+RH RV+TWTRH Sbjct: 689 FYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERR-NHETTNLSIQQKRHGRVKTWTRH 747 Query: 778 INIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDN- 836 ++IF KD+IFVP+NE++HW+LAV+CFP LE+ YE P ++N I Sbjct: 748 VDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPH-----------YHENAVIQKC 796 Query: 837 DLRTTSTLSLSAEDSQSTESNMS----VPKKMCKRPCILILDSLKAASVQNTVQNLREYL 892 S +S SA + +S N S + K + K+ CI ++DS ++ + R Sbjct: 797 STVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDS-NPGQEESDPRYKRNIC 855 Query: 893 EVEWEVKLKTH 903 V++ VK H Sbjct: 856 SVKYSVKKINH 866 Score = 149 bits (376), Expect = 1e-35 Identities = 75/135 (55%), Positives = 99/135 (73%), Gaps = 1/135 (0%) Query: 848 AEDSQSTE-SNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQF 906 A+D+ S+E + +CK+PCIL++DSL+ S N V+ LREYLEVEWEVK + R F Sbjct: 950 ADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSF 1009 Query: 907 SKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHVIKTKRE 966 SK M PKVP+Q+N SDCGVY+LQYVESFF++PI++FELP++L WFP ++TKRE Sbjct: 1010 SKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKRE 1069 Query: 967 DIRELILKLHLQQQK 981 +IR +ILKL Q K Sbjct: 1070 EIRNIILKLQEDQSK 1084 >gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens] Length = 643 Score = 67.0 bits (162), Expect = 8e-11 Identities = 54/252 (21%), Positives = 106/252 (42%), Gaps = 80/252 (31%) Query: 695 LGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNL 754 L +T +D++ L +LND II+FY+ +++E++ ++ + H F++FF+ Sbjct: 450 LTITRKDIQTLNHLNWLNDEIINFYMN-MLMERSKEKGLPSVHAFNTFFFT--------- 499 Query: 755 TEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDF 814 + ++ V+ WT+ +++F+ D + VP++ HW LAV+ F Sbjct: 500 -------KLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDF----------- 541 Query: 815 PQTVSQQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILD 874 +++ DS +N C ++L Sbjct: 542 ---------------------------RKKNITYYDSMGGINN---------EACRILLQ 565 Query: 875 SLKAASVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQY 934 LK S+ + +E+ W++ FSK + ++P+Q N SDCG++ +Y Sbjct: 566 YLKQESID---KKRKEFDTNGWQL-------FSKKS------QIPQQMNGSDCGMFACKY 609 Query: 935 VESFFKDPIVNF 946 + KD +NF Sbjct: 610 ADCITKDRPINF 621 >gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens] Length = 589 Score = 63.2 bits (152), Expect = 1e-09 Identities = 62/265 (23%), Positives = 109/265 (41%), Gaps = 86/265 (32%) Query: 695 LGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNL 754 L +T D++ L+ +LND +I+FY+ L++E+ + H+FS+FFY Sbjct: 395 LRITRGDIQTLKNYHWLNDEVINFYMN-LLVERNKKQGYPALHVFSTFFY---------- 443 Query: 755 TEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDF 814 P L ++ V+ WT+ +N+F ++ I VP++ HW L VI Sbjct: 444 ----PKLKSGG--YQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVI------------- 484 Query: 815 PQTVSQQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILD 874 DLR L DS + + R C ++L Sbjct: 485 ----------------------DLRKK---CLKYLDSMGQKGH---------RICEILLQ 510 Query: 875 SL--KAASVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLL 932 L ++ + +N+ NL +EW TH ++P+Q N SDCG++ Sbjct: 511 YLQDESKTKRNSDLNL-----LEW-----THHSMKP-------HEIPQQLNGSDCGMFTC 553 Query: 933 QYVESFFKDPIVNF---ELPIHLEK 954 +Y + +D + F ++P+ +K Sbjct: 554 KYADYISRDKPITFTQHQMPLFRKK 578 >gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens] Length = 755 Score = 58.5 bits (140), Expect = 3e-08 Identities = 53/235 (22%), Positives = 90/235 (38%), Gaps = 86/235 (36%) Query: 700 EDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNP 759 +DL L+ +LND +I+ Y + ++ D + ++ H F+SFF++ L K N Sbjct: 572 DDLATLDGQNWLNDQVINMYGELIM-----DAVPDKVHFFNSFFHRQLVTKGYN------ 620 Query: 760 NLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVS 819 V+ WT+ +++F K + +P++ HW L + Sbjct: 621 ----------GVKRWTKKVDLFKKSLLLIPIHLEVHWSLITV------------------ 652 Query: 820 QQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAA 879 T S +S DSQ + K C Sbjct: 653 --------------------TLSNRIISFYDSQ------GIHFKFC-------------- 672 Query: 880 SVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQY 934 V+N+R+YL E + K +F + + +P+Q N SDCGV++LQY Sbjct: 673 -----VENIRKYLLT--EAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY 720 >gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens] Length = 574 Score = 50.8 bits (120), Expect = 6e-06 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 21/102 (20%) Query: 697 VTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTE 756 +T +DL L +LND +++ Y ++ D + E+ H F+SFFY L K Sbjct: 388 LTMDDLGTLYGQNWLNDQVMNMYGDLVM-----DTVPEKVHFFNSFFYDKLRTKG----- 437 Query: 757 DNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYL 798 + V+ WT++++IFNK+ + +P++ HW L Sbjct: 438 -----------YDGVKRWTKNVDIFNKELLLIPIHLEVHWSL 468 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 49.7 bits (117), Expect = 1e-05 Identities = 56/297 (18%), Positives = 117/297 (39%), Gaps = 12/297 (4%) Query: 120 NDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQS-LNLSERGSQRSKTVDDNSAKQTA 178 + +N D++ S S S DS ++ + S N S S S + + + + ++ Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807 Query: 179 HNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTK 238 + + D S SD+ +S S S + D SDS +R Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS------NRSDS 861 Query: 239 RRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKS 298 ++ S S D S + +S+ S++ S++ D + + S Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921 Query: 299 DFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGIS-SLVEKDENELNTIEKP 357 D SS +S SN++ S+++ ++++ ++SNS D S S D ++ N+ + Sbjct: 922 D----SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977 Query: 358 ILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESA 414 ++ + S S++ S SS+ + D ++++ ++S+S+ Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034 Score = 45.4 bits (106), Expect = 3e-04 Identities = 52/289 (17%), Positives = 105/289 (36%), Gaps = 19/289 (6%) Query: 126 DANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRR 185 D++ SDS S+ DS ++ + S + S S +S+K + + + Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638 Query: 186 KDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNL 245 K D SD+ D + S D + + SDS + ++ Sbjct: 639 KSDS-----SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693 Query: 246 PDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSS 305 S S D S D S S S++ + ++ + S + SS Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753 Query: 306 LNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNEG 365 +S SN++ S+ + ++++ ++SNS D + N+ + ++ Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD----------SNDSSNSSDSSDSSNSSDS 803 Query: 366 NQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESA 414 + S S++ SSD SS+ D ++++ +S+S+ Sbjct: 804 SNSSDSSD----SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848 Score = 39.7 bits (91), Expect = 0.014 Identities = 55/303 (18%), Positives = 111/303 (36%), Gaps = 12/303 (3%) Query: 120 NDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAH 179 +D++ + SDS S S DS ++ S N S+ + + +S+ + Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752 Query: 180 NKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKR 239 + D S SD+ +S S S + D S + + + S + Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812 Query: 240 RLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSD 299 ++ DS S D S +S+ S++ S+ D + + SD Sbjct: 813 ---SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869 Query: 300 FTKLS-------SLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDE--NE 350 + S S +S E + S+ + +S S +++ ++SNS D S+ + E N Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929 Query: 351 LNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENEST 410 + ++ + S S+ S+ + SS+ S +++ ++S+ Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989 Query: 411 SES 413 S Sbjct: 990 DSS 992 Score = 39.3 bits (90), Expect = 0.018 Identities = 53/296 (17%), Positives = 108/296 (36%), Gaps = 10/296 (3%) Query: 120 NDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAH 179 + +N D++ SDS S S DS ++ + S + S S D+S + Sbjct: 955 DSSNSSDSSN-SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013 Query: 180 NKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKR 239 + S + + D + S D + + SDS Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073 Query: 240 RLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENY-HQDPKLPEEITTKPTKS 298 ++ S+ S D S DS+ S++ S++ D + + S Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133 Query: 299 DFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPI 358 D SS +S S++++S+ + ++++ ++S+S D SS + N+ + Sbjct: 1134 D----SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD----SSDSSDSSDSSNSSDSSD 1185 Query: 359 LRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESA 414 ++ + S S++ S + SS+ D +NE+ +S+S+ Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241 Score = 38.1 bits (87), Expect = 0.041 Identities = 52/290 (17%), Positives = 109/290 (37%), Gaps = 17/290 (5%) Query: 131 QSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGI 190 +SDS S S DS + + S S S S + D +S+ ++++ + D Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSSN--SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696 Query: 191 -SLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQ 249 S SD+ + S D S + D S + + S + +N DS Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756 Query: 250 YCTSLDKSTEQTKKQE-----DDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLS 304 + S++ + + D S S + + + D + + SD + S Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816 Query: 305 SLNSQELT-LSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHN 363 +S + SN++ S+ + +++++ ++S+S D D + N + + Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD--------GSDSDSSNRSDSSNSSDSS 868 Query: 364 EGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSES 413 + + S S++ S E SS+ +++N ++S+ S Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918 Score = 37.7 bits (86), Expect = 0.053 Identities = 46/260 (17%), Positives = 98/260 (37%), Gaps = 11/260 (4%) Query: 159 SERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRN 218 S+ G +S + D +S+ + + D SD+ + +S S D +S + Sbjct: 540 SDSGKGKSDSSDSDSSDSSNSSDSSDSSD-------SDSSDSNSSSDSDSSDSDSSDSSD 592 Query: 219 KDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPS 278 D S + + + S + ++ DS+ +S +S + DS+ S + Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652 Query: 279 ENYHQDPKLPEEITTKPTKSDFTKLS----SLNSQELTLSNATKSASAGSTTETVENSNS 334 + D + SD + S S NS + + S+ + ++S S + +S+S Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712 Query: 335 IDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILK 394 D S+ D + N+ + ++ + S S+ S + SS+ Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772 Query: 395 LQSKQDRETTNENESTSESA 414 D ++++ +S S+ Sbjct: 773 SSDSSDSSNSSDSNDSSNSS 792 Score = 37.7 bits (86), Expect = 0.053 Identities = 54/293 (18%), Positives = 111/293 (37%), Gaps = 11/293 (3%) Query: 122 ANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNK 181 +N D + S S S DS ++ + S N S+ S S + D NS+ + + Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSD----SSNSSD-SSNSSDSSDSNSSDSSDSSN 981 Query: 182 EKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRL 241 D S SD+ +S S S + D S + S + Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041 Query: 242 RNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFT 301 ++ DS S D S DS+ S++ S++ ++ + S + Sbjct: 1042 SSDSSDSS--DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099 Query: 302 KLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRG 361 SS +S S+++ S+ + +++++ ++S+S D SS + ++ E Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD----SSDSSNSSDSSDSSESSDSSD 1155 Query: 362 HNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESA 414 ++ + S S++ S + SS+ D ++++ +S+S+ Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208 Score = 36.2 bits (82), Expect = 0.16 Identities = 51/268 (19%), Positives = 104/268 (38%), Gaps = 19/268 (7%) Query: 126 DANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRR 185 D++ S S S DS ++ + S S S+ S + D +++ ++ + + Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD--SSDSSESSDSSDSSNSSDSSDSSDSSD 1104 Query: 186 KDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNL 245 D SD+ +S S S + D S + + + S + ++ Sbjct: 1105 SSDS-----SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159 Query: 246 PDSQYCT-SLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLS 304 DS + S D S DS+ S++ S++ ++ + S + S Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1219 Query: 305 SLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEK--DENELNTIEKPILRGH 362 S +S S++ +S+ + ++++ ++SNS D S + D N+ + + G+ Sbjct: 1220 SDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGN 1279 Query: 363 NEGNQSLISAEPIVVSSDEEGPVEHKSS 390 N G+ S SD EG + S+ Sbjct: 1280 NNGSDS---------DSDSEGSDSNHST 1298 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 46.2 bits (108), Expect = 2e-04 Identities = 67/321 (20%), Positives = 128/321 (39%), Gaps = 77/321 (23%) Query: 144 ETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLN 203 E C + ++Q N + G ++SK + D ++K +KD+ +SD + Sbjct: 986 EICHFPKGIKQIKNGTTDGEKKSKKIRDKTSK---------KKDE-----LSDYAEKSTG 1031 Query: 204 SGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQY-------CTSLDK 256 G CD E + ++K+ Y K L+ + +++R + D++ C S DK Sbjct: 1032 KGD-SCDSSE-DKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDK 1089 Query: 257 -------------STEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKL 303 S+++ K+ + S++ E+ SE D K ++ T+ K+ K Sbjct: 1090 RLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSE----DNKKKKQRTSSKKKAVIVKE 1145 Query: 304 SSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTI-EKPILRGH 362 NS L S K A S++ + + + +G S DE ++ + E +L H Sbjct: 1146 KKRNS--LRTSTKRKQADITSSSSSDIEDDDQNSIGEGS---SDEQKIKPVTENLVLSSH 1200 Query: 363 -----NEGNQSLISAEPIVV--------------------------SSDEEGPVEHKSSE 391 + G+++L + P+ V SSDE+G + + E Sbjct: 1201 TGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE 1260 Query: 392 ILKLQSKQDRETTNENESTSE 412 K KQ+ E + E+ ++ Sbjct: 1261 GKKRTGKQNEENPGDEEAKNQ 1281 Score = 37.4 bits (85), Expect = 0.070 Identities = 64/299 (21%), Positives = 119/299 (39%), Gaps = 62/299 (20%) Query: 118 PRNDANLCDANKVQSDSLPSTSV-----------DSLETCQKLEPLRQSLNLSERGSQRS 166 P+ ++ C+ + + D S SV + ++ +KL + + N++ + Sbjct: 279 PKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKL--IETTANMNSSYVKFL 336 Query: 167 KTVDDNSAKQTAHNKEKRRKDDGISLLISDTQP------EDLNSGSRGCDHLEQESRNKD 220 K DNS +A K R+ +++D + EDLNS R D + +E K+ Sbjct: 337 KQATDNSEISSA---TKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKE 393 Query: 221 VKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSEN 280 K D+K E TK R + P + + KS + +++ D SE+ Sbjct: 394 HKVIDAKFE-------TKAR-KGEKPCALEKKDISKSEAKLSRKQVD----------SEH 435 Query: 281 YHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGI 340 HQ+ E+ T K T + K + +N T+E ++ +DIV + Sbjct: 436 MHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPAN---------TSEDLD----MDIVSV 482 Query: 341 SSLVEKD--ENELNTIEKPILRGH----NEGNQSLISAEPI---VVSSDEEGPVEHKSS 390 S V +D EN +E H + G + + + + + S D G ++ K++ Sbjct: 483 PSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTT 541 Score = 35.0 bits (79), Expect = 0.35 Identities = 43/179 (24%), Positives = 74/179 (41%), Gaps = 10/179 (5%) Query: 114 RKTLPRNDANLCDA---NKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVD 170 ++T +N+ N D N+V S+S S S +S + + LR L +S+ S K Sbjct: 1263 KRTGKQNEENPGDEEAKNQVNSES-DSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1321 Query: 171 DNSAKQT-AHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVE 229 K+ N+ K +D SD Q ++ + EQ R + K ++ + Sbjct: 1322 PKEHKEVKGRNRRKVSSEDSED---SDFQESGVSEEVSESED-EQRPRTRSAKKAELEEN 1377 Query: 230 LTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLP 288 +K KRR DS + E+ +K+E++ E E+ E+ + D K P Sbjct: 1378 QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE-EEEEEEEEEDENDDSKSP 1435 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 46.2 bits (108), Expect = 2e-04 Identities = 67/321 (20%), Positives = 128/321 (39%), Gaps = 77/321 (23%) Query: 144 ETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLN 203 E C + ++Q N + G ++SK + D ++K +KD+ +SD + Sbjct: 1024 EICHFPKGIKQIKNGTTDGEKKSKKIRDKTSK---------KKDE-----LSDYAEKSTG 1069 Query: 204 SGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQY-------CTSLDK 256 G CD E + ++K+ Y K L+ + +++R + D++ C S DK Sbjct: 1070 KGD-SCDSSE-DKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDK 1127 Query: 257 -------------STEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKL 303 S+++ K+ + S++ E+ SE D K ++ T+ K+ K Sbjct: 1128 RLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSE----DNKKKKQRTSSKKKAVIVKE 1183 Query: 304 SSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTI-EKPILRGH 362 NS L S K A S++ + + + +G S DE ++ + E +L H Sbjct: 1184 KKRNS--LRTSTKRKQADITSSSSSDIEDDDQNSIGEGS---SDEQKIKPVTENLVLSSH 1238 Query: 363 -----NEGNQSLISAEPIVV--------------------------SSDEEGPVEHKSSE 391 + G+++L + P+ V SSDE+G + + E Sbjct: 1239 TGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE 1298 Query: 392 ILKLQSKQDRETTNENESTSE 412 K KQ+ E + E+ ++ Sbjct: 1299 GKKRTGKQNEENPGDEEAKNQ 1319 Score = 37.4 bits (85), Expect = 0.070 Identities = 64/299 (21%), Positives = 119/299 (39%), Gaps = 62/299 (20%) Query: 118 PRNDANLCDANKVQSDSLPSTSV-----------DSLETCQKLEPLRQSLNLSERGSQRS 166 P+ ++ C+ + + D S SV + ++ +KL + + N++ + Sbjct: 317 PKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKL--IETTANMNSSYVKFL 374 Query: 167 KTVDDNSAKQTAHNKEKRRKDDGISLLISDTQP------EDLNSGSRGCDHLEQESRNKD 220 K DNS +A K R+ +++D + EDLNS R D + +E K+ Sbjct: 375 KQATDNSEISSA---TKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKE 431 Query: 221 VKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSEN 280 K D+K E TK R + P + + KS + +++ D SE+ Sbjct: 432 HKVIDAKFE-------TKAR-KGEKPCALEKKDISKSEAKLSRKQVD----------SEH 473 Query: 281 YHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGI 340 HQ+ E+ T K T + K + +N T+E ++ +DIV + Sbjct: 474 MHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPAN---------TSEDLD----MDIVSV 520 Query: 341 SSLVEKD--ENELNTIEKPILRGH----NEGNQSLISAEPI---VVSSDEEGPVEHKSS 390 S V +D EN +E H + G + + + + + S D G ++ K++ Sbjct: 521 PSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTT 579 Score = 35.0 bits (79), Expect = 0.35 Identities = 43/179 (24%), Positives = 74/179 (41%), Gaps = 10/179 (5%) Query: 114 RKTLPRNDANLCDA---NKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVD 170 ++T +N+ N D N+V S+S S S +S + + LR L +S+ S K Sbjct: 1301 KRTGKQNEENPGDEEAKNQVNSES-DSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1359 Query: 171 DNSAKQT-AHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVE 229 K+ N+ K +D SD Q ++ + EQ R + K ++ + Sbjct: 1360 PKEHKEVKGRNRRKVSSEDSED---SDFQESGVSEEVSESED-EQRPRTRSAKKAELEEN 1415 Query: 230 LTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLP 288 +K KRR DS + E+ +K+E++ E E+ E+ + D K P Sbjct: 1416 QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE-EEEEEEEEEDENDDSKSP 1473 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 46.2 bits (108), Expect = 2e-04 Identities = 102/521 (19%), Positives = 193/521 (37%), Gaps = 65/521 (12%) Query: 2 DKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPL 61 D++ + + EI+ E KR+K + +EI+++ N+ D SK S E Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD-------SKRDSLE------ 49 Query: 62 QWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRND 121 E LR+ + + +N + R + + + L + + RK K R D Sbjct: 50 --EGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQ----QMSRK-EKVHHRKD 102 Query: 122 ANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNK 181 + + ++ E R+ + E+ R + + + Sbjct: 103 EKRKEKKHARVKE------------KEREHERRKRHREEQDKARREWERQKRREMAREHS 150 Query: 182 EKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRL 241 + R +DG+ L D + R EQ+ ++ K + + E R+ +R Sbjct: 151 RRERGNDGVCLF-RDRLEQLERKRERERKMREQQKEQREQKERERRAE----ERRKEREA 205 Query: 242 RNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFT 301 R + D S + S E+ + P E++ + SD Sbjct: 206 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 265 Query: 302 KLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRG 361 +S +S+ T S + SA +GS +E E + S+ E +E E E+ G Sbjct: 266 DIS--DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 323 Query: 362 HNEGNQSLISAEPI---VVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSE------ 412 N S SAE + +S DEE E+++ ++ +S+ DR++ E+ E Sbjct: 324 SNSEEASEQSAEEVSEEEMSEDEER--ENENHLLVVPESRFDRDSGESEEAEEEVGEGTP 381 Query: 413 --SALLELPLI----TCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGK 466 SAL E + +++ EL Y P ++ S+ ++ + + VY K Sbjct: 382 QSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 441 Query: 467 IKGASKGCVTITKKYIKIPFQ------VSLNEISLLVDTTH 501 K + + K +K+ + SL EI+ ++ H Sbjct: 442 DKKTDE---IVALKRLKMEKEKEGFPITSLREINTILKAQH 479 >gi|56676335 RAP1 interacting factor 1 [Homo sapiens] Length = 2472 Score = 45.8 bits (107), Expect = 2e-04 Identities = 67/329 (20%), Positives = 135/329 (41%), Gaps = 53/329 (16%) Query: 124 LCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNL-------SERGSQRSKTVDDNSAKQ 176 L D+ V +SL T + E K+E +++ + +E +++KT++ N + Sbjct: 1866 LGDSKNVSQESL-ETKEEKPEETPKMELSLENVTVEGNACKVTESNLEKAKTMELNVGNE 1924 Query: 177 TAHNKEKRRKDDGIS--LLISDTQPED---LNSGSRGCDHLEQESRNKDVKYSDSK--VE 229 + + ++R K GIS I + + D ++ + E N D+ SD+ V+ Sbjct: 1925 ASFHGQERTKT-GISEEAAIEENKRNDDSEADTAKLNAKEVATEEFNSDISLSDNTTPVK 1983 Query: 230 LTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPE 289 L + +++ L + L S E K +++ + E +E H E Sbjct: 1984 LNAQTEISEQTAAGELDGGNDVSDLHSSEETNTKMKNNEEMMIG-EAMAETGHDGETENE 2042 Query: 290 EITTKPTKSDFTKLSSLN-------------SQELTLSNATKSASAGSTTETVENSNSID 336 ITTK +K D + + L S E + +A K+ + +++ E ++ Sbjct: 2043 GITTKTSKPDEAETNMLTAEMDNFVCDTVEMSTEEGIIDANKTETNTEYSKSEEKLDNNQ 2102 Query: 337 IVGISSLVEKDENELNTIEKP-------------ILRGHNEGNQSLISAEPIVVSSDEE- 382 +V S ++++D + +E+P I+ +N Q L +P +VS+++ Sbjct: 2103 MVMESDILQEDHHTSQKVEEPSQCLASGTAISELIIEDNNASPQKLRELDPSLVSANDSP 2162 Query: 383 ---------GPVEHKSSEILKLQSKQDRE 402 P+ S+ ILK K+ +E Sbjct: 2163 SGMQTRCVWSPLASPSTSILKRGLKRSQE 2191 Score = 37.4 bits (85), Expect = 0.070 Identities = 62/292 (21%), Positives = 119/292 (40%), Gaps = 47/292 (16%) Query: 148 KLEPLRQSLNLSERGSQRSKTVD---DNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNS 204 ++ P +++L S R +RS+ V+ ++ K+ +H K++RRK++ L S Sbjct: 1406 QITPNQKTLRRSSR--RRSEVVESTTESQDKENSHQKKERRKEEEKPLQKSPL------- 1456 Query: 205 GSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYC-TSLDKSTEQTKK 263 H++ + K ++ ++ LI + +NL + TS + TEQ KK Sbjct: 1457 ------HIKDDVLPKQKLIAEQTLQENLIEK------GSNLHEKTLGETSANAETEQNKK 1504 Query: 264 QEDDSTISTEFEKPSENYHQ-DPKLPEEITTKPT-KSDFTKLSSLNSQELTLSNATKSAS 321 + D I +E + + + KL T T ++ LSS+ + E S A + S Sbjct: 1505 KADPENIKSEGDGTQDIVDKSSEKLVRGRTRYQTRRASQGLLSSIENSESDSSEAKEEGS 1564 Query: 322 AGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAE-------P 374 + +N + + V+ + E +++ ++ N+ + ++E P Sbjct: 1565 RKKRSGKWKNKS-------NESVDIQDQEEKVVKQECIKAENQSHDYKATSEEDVSIKSP 1617 Query: 375 IVVSSDEEGPVEHKSSEILK--LQSKQDR----ETTNENESTSESALLELPL 420 I DE V + S + LQ D E NE +E + LP+ Sbjct: 1618 ICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPV 1669 Score = 35.0 bits (79), Expect = 0.35 Identities = 73/382 (19%), Positives = 151/382 (39%), Gaps = 39/382 (10%) Query: 70 KVISLDHKNKKHIR---GCPVTS-KSSPERQLKVMLTNVLWTDLG----RKFRKTLPRND 121 + + HK + +R GC KS P+ + + L N D+ +K P + Sbjct: 1714 QTLECQHKRSRRVRRSKGCDCCGEKSQPQEKSLIGLKNTENNDVEISETKKADVQAPVSP 1773 Query: 122 ANLCDANKVQSDSLPST--SVD-SLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTA 178 + AN SV+ L + + + SL +SE S+ + T+ ++ Sbjct: 1774 SETSQANPYSEGQFLDEHHSVNFHLGLKEDNDTINDSLIVSETKSKEN-TMQESLPSGIV 1832 Query: 179 HNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTK 238 + +E+ D + ++Q E N + +S+N + ++K E + K + Sbjct: 1833 NFREEICDMDSSEAMSLESQ-ESPNENFKTVGPCLGDSKNVSQESLETKEEKPEETPKME 1891 Query: 239 RRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEF---EKPSENYHQDPKLPEEITTKP 295 L N + C + + E+ K E + F E+ ++ + E Sbjct: 1892 LSLENVTVEGNACKVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDD 1951 Query: 296 TKSDFTKLSSLN------SQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDEN 349 +++D KL++ + +++LS+ T + TE E + + ++ G D + Sbjct: 1952 SEADTAKLNAKEVATEEFNSDISLSDNTTPVKLNAQTEISEQTAAGELDG-----GNDVS 2006 Query: 350 ELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENES 409 +L++ E+ + N N+ ++ E + + +G E++ I SK D TN Sbjct: 2007 DLHSSEETNTKMKN--NEEMMIGEAMA-ETGHDGETENEG--ITTKTSKPDEAETN---- 2057 Query: 410 TSESALLELPLITCESVQMSSE 431 E+ C++V+MS+E Sbjct: 2058 ---MLTAEMDNFVCDTVEMSTE 2076 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 43.9 bits (102), Expect = 7e-04 Identities = 111/545 (20%), Positives = 202/545 (37%), Gaps = 111/545 (20%) Query: 2 DKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPL 61 D++ + + EI+ E KR+K + +EI+++ N+ D SK S E Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD-------SKRDSLE------ 49 Query: 62 QWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRND 121 E LR DH+ + IR P + S E D G + + Sbjct: 50 --EGELR------DHRMEITIRNSPYRREDSME-------------DRGEEDDSLAIKPP 88 Query: 122 ANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNK 181 + KV +K + R+ + S G + ++ + K+ H + Sbjct: 89 QQMSRKEKVHH-----------RKDEKRKEKRRHRSHSAEGGKHARVKE----KEREHER 133 Query: 182 EKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRL 241 KR +++ D + R E R +D ++E R+ +R++ Sbjct: 134 RKRHREE------QDKARREWERQKRREMAREHSRRERD------RLEQLERKRERERKM 181 Query: 242 RNNLPDSQYCTSLDKSTEQTKKQ-EDDSTISTEFEKPSENY----------HQDPKLPEE 290 R + + ++ E+ +K+ E +S E+Y P+ P E Sbjct: 182 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE 241 Query: 291 ITT-----KPTKSDFTK----LSSL----NSQELTLSNATKSASAGSTTETVENSNSIDI 337 KP K + + LS L +S+ T S + SA +GS +E E + Sbjct: 242 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 301 Query: 338 VGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPI---VVSSDEEGPVEHKSSEILK 394 S+ E +E E E+ G N S SAE + +S DEE E+++ ++ Sbjct: 302 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER--ENENHLLVV 359 Query: 395 LQSKQDRETTNENESTSE--------SALLELPLI----TCESVQMSSELCPYNPVMENI 442 +S+ DR++ E+ E SAL E + +++ EL Y P ++ Sbjct: 360 PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 419 Query: 443 SSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKKYIKIPFQ------VSLNEISLL 496 S+ ++ + + VY K K + + K +K+ + SL EI+ + Sbjct: 420 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDE---IVALKRLKMEKEKEGFPITSLREINTI 476 Query: 497 VDTTH 501 + H Sbjct: 477 LKAQH 481 >gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] Length = 1462 Score = 43.5 bits (101), Expect = 0.001 Identities = 89/432 (20%), Positives = 160/432 (37%), Gaps = 38/432 (8%) Query: 20 KRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKNK 79 + K S SD S K + E SP S+ RSS + + RS R+ S Sbjct: 667 REKNSESDQSTYSKYSDRSSES----SPRSRSRSSRSRSYSRSYTRS-RSLASSHSRSRS 721 Query: 80 KHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRNDANLCDANKVQSDSLPST- 138 R S + + + +D GR+ ++ L + ++K S S T Sbjct: 722 PSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTL 781 Query: 139 ------SVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISL 192 D +K R SL+ S Q S A Q+A KEK+ + + Sbjct: 782 HSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSV-----QATQSAQEKEKQGQMERTHN 836 Query: 193 LISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCT 252 + E+ + R C H ++ + +++ SD R + R N S++ + Sbjct: 837 KQEKNRGEEKSKSERECPHSKKRTLKENL--SDHL-------RNGSKPKRKNYAGSKWDS 887 Query: 253 SLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPE-EITTKPT--KSDFTKLSSLNSQ 309 + + TK ++DS S++ E+ + ++ E I KPT S T L N Sbjct: 888 ESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGA 947 Query: 310 ELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNE----- 364 + T ++ + + EN+ E + E K L+G + Sbjct: 948 WKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKA 1007 Query: 365 --GNQSLISAEPIVVSSDEEGPVEHK--SSEILKLQSKQDRETTNENESTSESALLELPL 420 Q+ P+ +EE ++ K + E + + ++ ET +N +E + E Sbjct: 1008 PKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLS 1067 Query: 421 ITCESVQMSSEL 432 ++V +SS+L Sbjct: 1068 GKHDTVTVSSDL 1079 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 42.7 bits (99), Expect = 0.002 Identities = 61/260 (23%), Positives = 100/260 (38%), Gaps = 31/260 (11%) Query: 213 EQESRNKDVKYSDSKVELTL-------ISRKTKRRL----------RNNLPDSQYCTSLD 255 E+ R +D +D+ EL + R+ R L + +L + Q T + Sbjct: 992 EESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEE 1051 Query: 256 KSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSN 315 + E+ +++EDD ++ SEN +D L E SD +E T+S Sbjct: 1052 EEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSD---------EEETVSI 1102 Query: 316 ATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNE--GNQSLISAE 373 T A A S++E+ E+S S +DE E+ E+ E +S+ SA Sbjct: 1103 VTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAG 1162 Query: 374 PIVVSSD-EEGPVEHKSSEI--LKLQSKQDRETTNENESTSESALLELPLITCESVQMSS 430 P D EE + + + L ++ + D ET S L E PL S Sbjct: 1163 PEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADS 1222 Query: 431 ELCPYNPVMENISSIMPSNE 450 P P + +++ S E Sbjct: 1223 REPPEEPGLSQEGAMLLSPE 1242 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 42.4 bits (98), Expect = 0.002 Identities = 92/473 (19%), Positives = 183/473 (38%), Gaps = 74/473 (15%) Query: 124 LCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEK 183 L AN + D+++ ++LE ++ L ++R + V+ +AK ++ K K Sbjct: 1363 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKL--AQRLQDAEEAVEAVNAKCSSLEKTK 1420 Query: 184 RRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRN 243 R + I L+ D + + + + L+++ RN D K + Sbjct: 1421 HRLQNEIEDLMVDVERSNAAAAA-----LDKKQRNFD---------------KILAEWKQ 1460 Query: 244 NLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKL 303 +SQ +E Q++ ++STE K Y + + E K Sbjct: 1461 KYEESQ--------SELESSQKEARSLSTELFKLKNAYEESLEHLETF----------KR 1502 Query: 304 SSLNSQELTLSNATKSASAGSTT----ETVENSNSIDIVGISSLVEKDENELNTIEKPIL 359 + N QE +S+ T+ G E V ++ + + S +E+ E L E IL Sbjct: 1503 ENKNLQE-EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKIL 1561 Query: 360 RGHNEGNQSLISAEPIVVSSDEEGPVEHKSSE--ILKLQSKQDRETTNENE-----STSE 412 R E NQ E + DEE ++ + + LQ+ D ET + NE E Sbjct: 1562 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621 Query: 413 SALLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASK 472 L E+ + + +M++E ++++ S++ ++ L D + + K Sbjct: 1622 GDLNEMEIQLSHANRMAAEA---QKQVKSLQSLLKDTQIQLD-DAV-------RANDDLK 1670 Query: 473 GCVTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYL 532 + I ++ + Q L E+ +V+ T R K + + S + + L Sbjct: 1671 ENIAIVERRNNL-LQAELEELRAVVEQTERSR----KLAEQELIETSERVQLLHSQNTSL 1725 Query: 533 QEIQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELE 585 + ++E + QS+ E + + E K K +T+ ++++ EL+ Sbjct: 1726 INQKKKMESDLTQLQSEVEEAV------QECRNAEEKAKKAITDAAMMAEELK 1772 >gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo sapiens] Length = 1393 Score = 42.0 bits (97), Expect = 0.003 Identities = 53/202 (26%), Positives = 83/202 (41%), Gaps = 28/202 (13%) Query: 229 ELTLISRKTKRRLRNNLPDSQYCTSLDKSTE--QTKKQEDDSTISTEFEKPSENYHQDPK 286 E+T SR + + + S K TE +T ED + S E P+EN + P Sbjct: 933 EITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAE---PTENGERTPL 989 Query: 287 LPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEK 346 E TT PT+S T+ + E T + + G E ++N I + E Sbjct: 990 ANENTTTSPTES--TEHGERTANEKTTPSPAEPTEHG---ERTPSANEKTIPSPAKPTEH 1044 Query: 347 DE-----NELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEH---------KSSEI 392 +E NE NT P+ + G ++ ++ E I +S EGP EH K + Sbjct: 1045 EEMTPSANE-NTTPSPV-KPTEHGEKTTLANEKITLS--PEGPTEHGAKTTSANEKITPS 1100 Query: 393 LKLQSKQDRETTNENESTSESA 414 L ++ TT+ N+ + SA Sbjct: 1101 LAKPTEHGERTTSPNDKITSSA 1122 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 41.2 bits (95), Expect = 0.005 Identities = 70/313 (22%), Positives = 121/313 (38%), Gaps = 50/313 (15%) Query: 124 LCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEK 183 L AN + D+++ ++LE ++ L ++R + + V+ +AK ++ K K Sbjct: 1361 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKL--AQRLQEAEEAVEAVNAKCSSLEKTK 1418 Query: 184 RRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRN 243 R + I L+ D + + + + L+++ RN D K + Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAA-----LDKKQRNFD---------------KILAEWKQ 1458 Query: 244 NLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKL 303 +SQ +E Q++ ++STE K Y + + E K Sbjct: 1459 KYEESQ--------SELESSQKEARSLSTELFKLKNAYEESLEHLETF----------KR 1500 Query: 304 SSLNSQELTLSNATKSASAGSTT---ETVENSNSIDIVGISSLVEKDENELNTIEKPILR 360 + N QE + S+G T E V + + + S +E+ E L E ILR Sbjct: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560 Query: 361 GHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILK----LQSKQDRETTNENESTSESALL 416 E NQ E + DEE +E L+ LQ+ D ET + NE+ + Sbjct: 1561 AQLEFNQIKAEIERKLAEKDEE--MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKM 1618 Query: 417 ELPLITCESVQMS 429 E L E +Q+S Sbjct: 1619 EGDLNEME-IQLS 1630 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 41.2 bits (95), Expect = 0.005 Identities = 85/417 (20%), Positives = 164/417 (39%), Gaps = 63/417 (15%) Query: 143 LETCQKLEPLRQSLNLSERGSQRS----KTVDDNSAKQTAHN-KEKRRKDDGISLLISDT 197 +E + P R+ ++ +RG + K S K+ H+ K+++RK+ + + Sbjct: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKER 117 Query: 198 QPEDLNSGSRGCDHLEQE---SRNKDVKYSDSKVELTLIS-----RKTKRRLRNNLPDSQ 249 + E D +E + +++ S+ E + R+ +R++R + + Sbjct: 118 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 177 Query: 250 YCTSLDKSTEQTKKQ-EDDSTISTEFEKPSENY----------HQDPKLPEEITT----- 293 ++ E+ +K+ E +S E+Y P+ P E Sbjct: 178 EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGR 237 Query: 294 KPTKSDFTK----LSSL----NSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVE 345 KP K + + LS L +S+ T S + SA +GS +E E + S+ E Sbjct: 238 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 297 Query: 346 KDENELNTIEKPILRGHNEGNQSLISAEPI---VVSSDEEGPVEHKSSEILKLQSKQDRE 402 +E E E+ G N S SAE + +S DEE E+++ ++ +S+ DR+ Sbjct: 298 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER--ENENHLLVVPESRFDRD 355 Query: 403 TTNENESTSE--------SALLELPLI----TCESVQMSSELCPYNPVMENISSIMPSNE 450 + E+ E SAL E + +++ EL Y P ++ S+ Sbjct: 356 SGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQC 415 Query: 451 MDLQLDFIFTSVYIGKIKGASKGCVTITKKYIKIPFQ------VSLNEISLLVDTTH 501 ++ + + VY K K + + K +K+ + SL EI+ ++ H Sbjct: 416 LNRIEEGTYGVVYRAKDKKTDE---IVALKRLKMEKEKEGFPITSLREINTILKAQH 469 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 41.2 bits (95), Expect = 0.005 Identities = 102/521 (19%), Positives = 196/521 (37%), Gaps = 65/521 (12%) Query: 2 DKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPL 61 D++ + + EI+ E KR+K + +EI+++ N+ D SK S E Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD-------SKRDSLE------ 49 Query: 62 QWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRND 121 E LR+ + + +N + R + + + L + + RK R + Sbjct: 50 --EGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKE 107 Query: 122 ANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNK 181 C + ++ V E ++ + R+ + + R +R K ++ + Sbjct: 108 K--CRHHSHSAEGGKHARVKEREH-ERRKRHREEQDKARREWERQK-------RREMARE 157 Query: 182 EKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRL 241 RR+ D + L + E EQ+ ++ K + + E R+ +R Sbjct: 158 HSRRERDRLEQLERKRERERKMR--------EQQKEQREQKERERRAE----ERRKEREA 205 Query: 242 RNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFT 301 R + D S + S E+ + P E++ + SD Sbjct: 206 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 265 Query: 302 KLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRG 361 +S +S+ T S + SA +GS +E E + S+ E +E E E+ G Sbjct: 266 DIS--DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 323 Query: 362 HNEGNQSLISAEPI---VVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSE------ 412 N S SAE + +S DEE E+++ ++ +S+ DR++ E+ E Sbjct: 324 SNSEEASEQSAEEVSEEEMSEDEER--ENENHLLVVPESRFDRDSGESEEAEEEVGEGTP 381 Query: 413 --SALLELPLI----TCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGK 466 SAL E + +++ EL Y P ++ S+ ++ + + VY K Sbjct: 382 QSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 441 Query: 467 IKGASKGCVTITKKYIKIPFQ------VSLNEISLLVDTTH 501 K + + K +K+ + SL EI+ ++ H Sbjct: 442 DKKTDE---IVALKRLKMEKEKEGFPITSLREINTILKAQH 479 >gi|109255234 centrosomal protein 290kDa [Homo sapiens] Length = 2479 Score = 41.2 bits (95), Expect = 0.005 Identities = 93/455 (20%), Positives = 189/455 (41%), Gaps = 46/455 (10%) Query: 13 SEIITEGKR-KKSSSDLSEIRKMLNAKPEDVHVQSPL-SKFRSSERWTLPLQWERSLRNK 70 +E I++G R + DL ++ M A+ ++ + L K R ER + +NK Sbjct: 580 TENISQGDRISERKLDLLSLKNMSEAQSKNEFLSRELIEKERDLERSRTVIA---KFQNK 636 Query: 71 VISLDHKNKKHIRGCPVTSKSSPERQ----LKVMLTNVLWTDLGRKFRKTLPRNDANLCD 126 + L +NK+ G ++ E Q +K T+++ L R +N + D Sbjct: 637 LKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFD 696 Query: 127 AN---KVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEK 183 A+ K Q D L + + + + E ++++N S++ ++ + +D + K+T+ ++ Sbjct: 697 ASLHLKAQVDQLTGRNEELRQELR--ESRKEAINYSQQLAKANLKID-HLEKETSLLRQS 753 Query: 184 RRKD---DGISLL--ISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRK-T 237 + GI L I+ + +NS + HL QE NK+ K + + L +RK Sbjct: 754 EGSNVVFKGIDLPDGIAPSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFA 813 Query: 238 KRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITT---- 293 R + +L +Y + +K T +T + TI E K + QD +E Sbjct: 814 VIRHQQSLLYKEYLS--EKETWKT----ESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNA 867 Query: 294 -KPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELN 352 + + K+ + NS+++T+ + + T VE + EK +NEL Sbjct: 868 LQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQ-----LRKENEKQKNELL 922 Query: 353 TIEKPIL-------RGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTN 405 ++E + R + + + +V +S +E + + +L +K Sbjct: 923 SMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSELELANKQYNELTAKYRDILQK 982 Query: 406 ENESTSESALLELPLITCESVQMSSELCPYNPVME 440 +N ++ LE + CE++ + ++ N +E Sbjct: 983 DNMLVQRTSNLE--HLECENISLKEQVESINKELE 1015 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 41.2 bits (95), Expect = 0.005 Identities = 67/306 (21%), Positives = 118/306 (38%), Gaps = 36/306 (11%) Query: 115 KTLPRNDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSA 174 KT +N+A+ + S S ET + + S +S+ SQ+ K NS Sbjct: 151 KTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQ---NSKTVSKNCSQKDKKDSKNSK 207 Query: 175 KQTA---HNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHL------EQESRNKDV---- 221 K H K +KD S +D E + S D L + ES N D Sbjct: 208 KTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRN 267 Query: 222 -KYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSEN 280 ++SK ++ TK+ + N S D +E +K + DS +K +N Sbjct: 268 YSQNNSKNYSLKYTKYTKKDTKKNAKKSS-----DAESEDSKDAKKDS------KKVKKN 316 Query: 281 YHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGI 340 +D K +++ +D S + ++ T + K +T + S D Sbjct: 317 VKKDDK-KKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTE-- 373 Query: 341 SSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQD 400 S + N+ ++K ++ + A+ I S+D E +E K S+ + + K+D Sbjct: 374 SGDAKDARNDSRNLKKA-----SKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKD 428 Query: 401 RETTNE 406 +T N+ Sbjct: 429 SKTDNK 434 Score = 40.8 bits (94), Expect = 0.006 Identities = 66/340 (19%), Positives = 129/340 (37%), Gaps = 54/340 (15%) Query: 2 DKRKLG----RRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERW 57 D +K G P S +I+ E ++++ +D + ++ H K +SS Sbjct: 130 DSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSS--------HENEQSKKSKSSSET 181 Query: 58 TLPLQWERSLRNKVISLDHKNKKHIRGCPVT---SKSSPERQLKVMLTNVLWTDLGRKFR 114 Q +++ D K+ K+ + +K++P++ LK T+ Sbjct: 182 NPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTS----------- 230 Query: 115 KTLPRND--ANLCDANKVQSDSL--------PSTSVDS-LETCQKLEPLRQSLNLSE--- 160 ND + +C N + D L S + D+ L + SL ++ Sbjct: 231 -----NDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTK 285 Query: 161 -------RGSQRSKTVDDNSAKQTAHNKEKR-RKDDGISLLISDTQPEDLNSGSRGCDHL 212 + S +++ D AK+ + +K +KDD + DT+ D SG + Sbjct: 286 KDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERK 345 Query: 213 EQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTIST 272 + + K +K D K + T + +L K+++ K++D I+ Sbjct: 346 DTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITF 405 Query: 273 EFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQELT 312 + SE ++ + E+ K +K+D K S N +E T Sbjct: 406 STDSESELESKESQKDEKKDKKDSKTD-NKKSVKNDEEST 444 >gi|87299628 biorientation of chromosomes in cell division 1-like [Homo sapiens] Length = 3051 Score = 40.8 bits (94), Expect = 0.006 Identities = 86/431 (19%), Positives = 165/431 (38%), Gaps = 57/431 (13%) Query: 2 DKRKLGRRPSSSEIITEGKRKKSSSDLSEIRK-MLNAKPEDVHVQSPLSKFRSSERWTLP 60 + K RR S+ + E K ++SS S+I+K L +K + +Q + + Sbjct: 823 ENNKKERRLSAEKTKAEHKSRRSSD--SKIQKDSLGSKQHGITLQRRSESYSEDKCDMDS 880 Query: 61 LQWERSLRNKVISLDHKNKKHIRGC-----PVTSKSSPE-RQLKVMLTNVLWTDLGRKFR 114 + +L+ + + HK K+ + + SKS + +Q+KV+ T + G + Sbjct: 881 TNMDSNLKPEEVV--HKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETEL---QEGATKQ 935 Query: 115 KTLPR---------NDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQR 165 T P+ ND+ +KV+ T V EP+ ++ + S +Q+ Sbjct: 936 ATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGV---------EPVLETASSSAHSTQK 986 Query: 166 SKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSD 225 D + + KEK + D + + + D + SR H ++ + KD SD Sbjct: 987 ----DSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHK-SRSLKHSSKDIKKKDENKSD 1041 Query: 226 SKVELTLISRKTKRRLRNNLPDS----QYCTSLDKSTEQTKKQEDDSTISTEFEKPSENY 281 K + S K R ++L + + C + S Q + ++ + PS + Sbjct: 1042 DKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSS 1101 Query: 282 HQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGIS 341 Q PK D T + E+ ++ S T+ N+NS + Sbjct: 1102 LQRPK---------KSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQDIDSE 1152 Query: 342 SLVEKDENELNTIEKPILRGHNEGNQSLISA----EPIVVSSDEEGPVEHKSSEILKLQS 397 ++ +K T++K LR +++ A V+S+ E +H+S+ K+ Sbjct: 1153 NMKQKTS---ATVQKDELRTCTADSKATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHI 1209 Query: 398 KQDRETTNENE 408 + N E Sbjct: 1210 QSAVSKMNPGE 1220 Score = 36.2 bits (82), Expect = 0.16 Identities = 36/196 (18%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 157 NLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQES 216 +LS+ ++ + + N+ + + +R K G LI + +P +++S G +++ + S Sbjct: 1077 SLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDS-EPGVENVFEVS 1135 Query: 217 RNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEK 276 + +D + ++S+ ++ + K K + + CT+ K+T K + +++ EK Sbjct: 1136 KTQDNRNNNSQQDIDSENMKQKTSATVQKDELRTCTADSKATAPAYKPGRGTGVNSNSEK 1195 Query: 277 PSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSID 336 +++ +S TK + S ++ K TTE +S ++ Sbjct: 1196 HADH----------------RSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVNIDSETVH 1239 Query: 337 IVGISSLVEKDENELN 352 + +S+ E D + N Sbjct: 1240 RMLLSAPSENDRVQKN 1255 Score = 33.5 bits (75), Expect = 1.0 Identities = 86/441 (19%), Positives = 168/441 (38%), Gaps = 58/441 (13%) Query: 8 RRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPLQWERSL 67 ++P S+E +G+RKK + +E + + K ED + + E +L L E++ Sbjct: 324 KKPDSNE---KGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKN- 379 Query: 68 RNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRNDANLCDA 127 NK +++ + S + + +++V +DL T + Sbjct: 380 SNKAKTVEGTKEDFS-----LIDSDVDGLTDITVSSVHTSDLSSFEEDT---------EE 425 Query: 128 NKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSA-KQTAHNKEKRRK 186 V SDS+ + S + +K + + S+ ++K+V K ++K Sbjct: 426 EVVTSDSMEEGEITSDDE-EKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDS 484 Query: 187 DDGISL-----LISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSK--------VELTLI 233 DD +++ I+ + E L + LE++ + K K SK V+L Sbjct: 485 DDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEES 544 Query: 234 SRKTKR----RLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPK--- 286 S K+ R++ L + + L+K +KK++ DS E K + Y +D K Sbjct: 545 STKSLEPKAARIKEVLKERKV---LEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETL 601 Query: 287 ------------LPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNS 334 +E+ KS+ +K + S+ L + + K+ S S Sbjct: 602 KTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTP 661 Query: 335 IDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILK 394 + + G+ + + + I + +S + E + D E P H S +LK Sbjct: 662 VIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETP--HLKS-LLK 718 Query: 395 LQSKQDRETTNENESTSESAL 415 + K +E ++ SE L Sbjct: 719 KEVKSSKEKPEREKTPSEDKL 739 Score = 31.2 bits (69), Expect = 5.0 Identities = 36/195 (18%), Positives = 70/195 (35%), Gaps = 24/195 (12%) Query: 126 DANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHN----- 180 + N + LP TS ++ T ++ + + SE ++ + DD++ K + Sbjct: 2812 EENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIII 2871 Query: 181 KEKR-------------RKDDG---ISLLISDTQPEDLNSGSRGCDHLEQESRN---KDV 221 K KR KDD ++ + P D +E+ N + + Sbjct: 2872 KRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSI 2931 Query: 222 KYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENY 281 D + ++ R+ R+ + +L S S + ++ K D E E E Sbjct: 2932 SNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEE 2991 Query: 282 HQDPKLPEEITTKPT 296 ++ P TT+ T Sbjct: 2992 EEEEDEPSGATTRST 3006 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 40.4 bits (93), Expect = 0.008 Identities = 99/521 (19%), Positives = 193/521 (37%), Gaps = 74/521 (14%) Query: 2 DKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPL 61 D++ + + EI+ E KR+K + +EI+++ N+ D SK S E Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD-------SKRDSLE------ 49 Query: 62 QWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRND 121 E LR+ + + +N + R + + + L + + RK R + Sbjct: 50 --EGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKE 107 Query: 122 ANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNK 181 + + + ++ + R+ + + R +R K ++ + Sbjct: 108 KKHARVKEKEREH------------ERRKRHREEQDKARREWERQK-------RREMARE 148 Query: 182 EKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRL 241 RR+ D + L + E EQ+ ++ K + + E R+ +R Sbjct: 149 HSRRERDRLEQLERKRERERKMR--------EQQKEQREQKERERRAE----ERRKEREA 196 Query: 242 RNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFT 301 R + D S + S E+ + P E++ + SD Sbjct: 197 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 256 Query: 302 KLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRG 361 +S +S+ T S + SA +GS +E E + S+ E +E E E+ G Sbjct: 257 DIS--DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 314 Query: 362 HNEGNQSLISAEPI---VVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSE------ 412 N S SAE + +S DEE E+++ ++ +S+ DR++ E+ E Sbjct: 315 SNSEEASEQSAEEVSEEEMSEDEER--ENENHLLVVPESRFDRDSGESEEAEEEVGEGTP 372 Query: 413 --SALLELPLI----TCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGK 466 SAL E + +++ EL Y P ++ S+ ++ + + VY K Sbjct: 373 QSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 432 Query: 467 IKGASKGCVTITKKYIKIPFQ------VSLNEISLLVDTTH 501 K + + K +K+ + SL EI+ ++ H Sbjct: 433 DKKTDE---IVALKRLKMEKEKEGFPITSLREINTILKAQH 470 >gi|38044112 restin isoform b [Homo sapiens] Length = 1392 Score = 40.0 bits (92), Expect = 0.011 Identities = 81/400 (20%), Positives = 160/400 (40%), Gaps = 42/400 (10%) Query: 24 SSSDLSEIRKMLNAKPEDVH-VQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKN---- 78 +SS L+++ L K DV +Q L+K + + ++S+ + + + Sbjct: 894 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFL-----QKSIEDMTVKAEQSQQEAA 948 Query: 79 KKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRK----TLPRNDANLCDANKV---Q 131 KKH + + + K+ ++ +L ++ + T +++ L + K Sbjct: 949 KKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDT 1008 Query: 132 SDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGIS 191 D L ++ Q+LE LR+ + ++ ++T +D A Q K + + S Sbjct: 1009 EDKLKGAREENSGLLQELEELRKQADKAKA----AQTAED--AMQIMEQMTKEKTETLAS 1062 Query: 192 LLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYC 251 L DT+ + + D L+ E+ K+V+ + EL + + R + + Sbjct: 1063 L--EDTKQTNAKLQNE-LDTLK-ENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQA 1118 Query: 252 TSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQEL 311 + KS + + QE++ ++ E + + KL EE S LN+Q L Sbjct: 1119 AA-QKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEE------------RSVLNNQLL 1165 Query: 312 TLSNATKSASAGSTTETVENSNSIDIVGISSLVEKD-ENELNTIEKPILRGHNEGNQSLI 370 + + E SI I + L EKD E E E +LRG N +SL Sbjct: 1166 EMKKRESKFIKDADEEKASLQKSISITS-ALLTEKDAELEKLRNEVTVLRGENASAKSLH 1224 Query: 371 SAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENEST 410 S + S + ++ K+ E+ ++K+ +++ N T Sbjct: 1225 SVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDT 1264 >gi|4506751 restin isoform a [Homo sapiens] Length = 1427 Score = 40.0 bits (92), Expect = 0.011 Identities = 81/400 (20%), Positives = 160/400 (40%), Gaps = 42/400 (10%) Query: 24 SSSDLSEIRKMLNAKPEDVH-VQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKN---- 78 +SS L+++ L K DV +Q L+K + + ++S+ + + + Sbjct: 929 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFL-----QKSIEDMTVKAEQSQQEAA 983 Query: 79 KKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRK----TLPRNDANLCDANKV---Q 131 KKH + + + K+ ++ +L ++ + T +++ L + K Sbjct: 984 KKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDT 1043 Query: 132 SDSLPSTSVDSLETCQKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGIS 191 D L ++ Q+LE LR+ + ++ ++T +D A Q K + + S Sbjct: 1044 EDKLKGAREENSGLLQELEELRKQADKAKA----AQTAED--AMQIMEQMTKEKTETLAS 1097 Query: 192 LLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYC 251 L DT+ + + D L+ E+ K+V+ + EL + + R + + Sbjct: 1098 L--EDTKQTNAKLQNE-LDTLK-ENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQA 1153 Query: 252 TSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQEL 311 + KS + + QE++ ++ E + + KL EE S LN+Q L Sbjct: 1154 AA-QKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEE------------RSVLNNQLL 1200 Query: 312 TLSNATKSASAGSTTETVENSNSIDIVGISSLVEKD-ENELNTIEKPILRGHNEGNQSLI 370 + + E SI I + L EKD E E E +LRG N +SL Sbjct: 1201 EMKKRESKFIKDADEEKASLQKSISITS-ALLTEKDAELEKLRNEVTVLRGENASAKSLH 1259 Query: 371 SAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENEST 410 S + S + ++ K+ E+ ++K+ +++ N T Sbjct: 1260 SVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDT 1299 >gi|20070262 TNF receptor-associated factor 3 interacting protein 1 isoform 1 [Homo sapiens] Length = 691 Score = 40.0 bits (92), Expect = 0.011 Identities = 43/193 (22%), Positives = 73/193 (37%), Gaps = 11/193 (5%) Query: 153 RQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHL 212 +Q L E R K D AK+ N+ + + + + G+R D Sbjct: 183 KQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRD 242 Query: 213 EQESRNKDVKYSDSKVELTLISR-------KTKRRLRNNLPDSQYCTSLD--KSTEQTKK 263 + + + K K + L R K K R R + + ++ LD K+ E K Sbjct: 243 SERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKP 302 Query: 264 QEDDSTISTEFEKPSENYHQDPK--LPEEITTKPTKSDFTKLSSLNSQELTLSNATKSAS 321 ++ ++ +K S+ +D K EI+T+ +KS TK S S+ + S Sbjct: 303 EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNIS 362 Query: 322 AGSTTETVENSNS 334 A S V N+ Sbjct: 363 AKSLDSIVSGINN 375 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 40.0 bits (92), Expect = 0.011 Identities = 82/400 (20%), Positives = 155/400 (38%), Gaps = 66/400 (16%) Query: 147 QKLEPLRQSLNLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGS 206 +K + R+ + S G + ++ + K+ H + KR +++ D + Sbjct: 69 EKRKEKRRHRSHSAEGGKHARVKE----KEREHERRKRHREE------QDKARREWERQK 118 Query: 207 RGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQ-E 265 R E R +D ++E R+ +R++R + + ++ E+ +K+ E Sbjct: 119 RREMAREHSRRERD------RLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 172 Query: 266 DDSTISTEFEKPSENY----------HQDPKLPEEITT-----KPTKSDFTK----LSSL 306 +S E+Y P+ P E KP K + + LS L Sbjct: 173 ARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDL 232 Query: 307 ----NSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGH 362 +S+ T S + SA +GS +E E + S+ E +E E E+ G Sbjct: 233 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 292 Query: 363 NEGNQSLISAEPI---VVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSE------- 412 N S SAE + +S DEE E+++ ++ +S+ DR++ E+ E Sbjct: 293 NSEEASEQSAEEVSEEEMSEDEER--ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 350 Query: 413 -SALLELPLI----TCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKI 467 SAL E + +++ EL Y P ++ S+ ++ + + VY K Sbjct: 351 SSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKD 410 Query: 468 KGASKGCVTITKKYIKIPFQ------VSLNEISLLVDTTH 501 K + + K +K+ + SL EI+ ++ H Sbjct: 411 KKTDE---IVALKRLKMEKEKEGFPITSLREINTILKAQH 447 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 40.0 bits (92), Expect = 0.011 Identities = 85/418 (20%), Positives = 163/418 (38%), Gaps = 64/418 (15%) Query: 143 LETCQKLEPLRQSLNLSERGSQRS----KTVDDNSAKQTAHNK--EKRRKDDGISLLISD 196 +E + P R+ ++ +RG + K S K+ H++ EKR++ + + Sbjct: 24 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKE 83 Query: 197 TQPEDLNSGSRGCDHLEQE---SRNKDVKYSDSKVELTLIS-----RKTKRRLRNNLPDS 248 + E D +E + +++ S+ E + R+ +R++R + Sbjct: 84 REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ 143 Query: 249 QYCTSLDKSTEQTKKQ-EDDSTISTEFEKPSENY----------HQDPKLPEEITT---- 293 + ++ E+ +K+ E +S E+Y P+ P E Sbjct: 144 REQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDG 203 Query: 294 -KPTKSDFTK----LSSL----NSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLV 344 KP K + + LS L +S+ T S + SA +GS +E E + S+ Sbjct: 204 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 263 Query: 345 EKDENELNTIEKPILRGHNEGNQSLISAEPI---VVSSDEEGPVEHKSSEILKLQSKQDR 401 E +E E E+ G N S SAE + +S DEE E+++ ++ +S+ DR Sbjct: 264 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER--ENENHLLVVPESRFDR 321 Query: 402 ETTNENESTSE--------SALLELPLI----TCESVQMSSELCPYNPVMENISSIMPSN 449 ++ E+ E SAL E + +++ EL Y P ++ S+ Sbjct: 322 DSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQ 381 Query: 450 EMDLQLDFIFTSVYIGKIKGASKGCVTITKKYIKIPFQ------VSLNEISLLVDTTH 501 ++ + + VY K K + + K +K+ + SL EI+ ++ H Sbjct: 382 CLNRIEEGTYGVVYRAKDKKTDE---IVALKRLKMEKEKEGFPITSLREINTILKAQH 436 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.360 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,192,652 Number of Sequences: 37866 Number of extensions: 1591149 Number of successful extensions: 5005 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 175 Number of HSP's that attempted gapping in prelim test: 4771 Number of HSP's gapped (non-prelim): 411 length of query: 985 length of database: 18,247,518 effective HSP length: 112 effective length of query: 873 effective length of database: 14,006,526 effective search space: 12227697198 effective search space used: 12227697198 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.