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Search of human proteins with 116063573
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
(2639 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens] 5385 0.0
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens] 5378 0.0
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s... 3802 0.0
gi|116805322 gamma filamin isoform a [Homo sapiens] 3331 0.0
gi|188595687 gamma filamin isoform b [Homo sapiens] 3311 0.0
gi|239755812 PREDICTED: similar to spectrin, beta, non-erythrocy... 191 8e-48
gi|12025678 actinin, alpha 4 [Homo sapiens] 166 4e-40
gi|4557241 actinin, alpha 3 [Homo sapiens] 159 5e-38
gi|4501893 actinin, alpha 2 [Homo sapiens] 153 2e-36
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 152 3e-36
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] 152 3e-36
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] 152 3e-36
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 144 1e-33
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 144 1e-33
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 143 3e-33
gi|67782321 spectrin beta isoform a [Homo sapiens] 142 3e-33
gi|67782319 spectrin beta isoform b [Homo sapiens] 142 3e-33
gi|33188445 microfilament and actin filament cross-linker protei... 139 4e-32
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 139 5e-32
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 139 5e-32
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 139 5e-32
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 139 5e-32
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 139 5e-32
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 139 5e-32
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 139 5e-32
gi|221316624 dystonin isoform 4 [Homo sapiens] 138 8e-32
gi|221316622 dystonin isoform 3 [Homo sapiens] 138 8e-32
gi|221316618 dystonin isoform 2 [Homo sapiens] 138 8e-32
gi|34577047 dystonin isoform 1 [Homo sapiens] 137 1e-31
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 137 2e-31
>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
Length = 2639
Score = 5385 bits (13969), Expect = 0.0
Identities = 2639/2639 (100%), Positives = 2639/2639 (100%)
Query: 1 MSSSHSRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCV 60
MSSSHSRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCV
Sbjct: 1 MSSSHSRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCV 60
Query: 61 SKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIK 120
SKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIK
Sbjct: 61 SKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIK 120
Query: 121 LVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL 180
LVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL
Sbjct: 121 LVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL 180
Query: 181 PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQ 240
PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQ
Sbjct: 181 PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQ 240
Query: 241 VITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKK 300
VITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKK
Sbjct: 241 VITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKK 300
Query: 301 RAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLF 360
RAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLF
Sbjct: 301 RAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLF 360
Query: 361 AGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVI 420
AGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVI
Sbjct: 361 AGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVI 420
Query: 421 QDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNP 480
QDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNP
Sbjct: 421 QDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNP 480
Query: 481 SACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGF 540
SACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGF
Sbjct: 481 SACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGF 540
Query: 541 EYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVE 600
EYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVE
Sbjct: 541 EYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVE 600
Query: 601 AIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFM 660
AIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFM
Sbjct: 601 AIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFM 660
Query: 661 ADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVE 720
ADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVE
Sbjct: 661 ADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVE 720
Query: 721 ALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVA 780
ALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVA
Sbjct: 721 ALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVA 780
Query: 781 KTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTP 840
KTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTP
Sbjct: 781 KTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTP 840
Query: 841 RGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAK 900
RGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAK
Sbjct: 841 RGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAK 900
Query: 901 AAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSP 960
AAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSP
Sbjct: 901 AAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSP 960
Query: 961 FSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKV 1020
FSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKV
Sbjct: 961 FSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKV 1020
Query: 1021 EPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGG 1080
EPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGG
Sbjct: 1021 EPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGG 1080
Query: 1081 SAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILF 1140
SAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILF
Sbjct: 1081 SAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILF 1140
Query: 1141 ADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSE 1200
ADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSE
Sbjct: 1141 ADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSE 1200
Query: 1201 AGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQC 1260
AGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQC
Sbjct: 1201 AGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQC 1260
Query: 1261 YGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVE 1320
YGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVE
Sbjct: 1261 YGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVE 1320
Query: 1321 YTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVET 1380
YTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVET
Sbjct: 1321 YTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVET 1380
Query: 1381 RGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKV 1440
RGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKV
Sbjct: 1381 RGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKV 1440
Query: 1441 PVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVV 1500
PVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVV
Sbjct: 1441 PVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVV 1500
Query: 1501 DNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGV 1560
DNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGV
Sbjct: 1501 DNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGV 1560
Query: 1561 PASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILI 1620
PASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILI
Sbjct: 1561 PASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILI 1620
Query: 1621 KYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTV 1680
KYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTV
Sbjct: 1621 KYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTV 1680
Query: 1681 CTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSV 1740
CTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSV
Sbjct: 1681 CTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSV 1740
Query: 1741 QPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEV 1800
QPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEV
Sbjct: 1741 QPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEV 1800
Query: 1801 RMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHV 1860
RMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHV
Sbjct: 1801 RMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHV 1860
Query: 1861 TAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVL 1920
TAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVL
Sbjct: 1861 TAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVL 1920
Query: 1921 PGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVV 1980
PGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVV
Sbjct: 1921 PGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVV 1980
Query: 1981 PPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDAS 2040
PPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDAS
Sbjct: 1981 PPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDAS 2040
Query: 2041 RVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCP 2100
RVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCP
Sbjct: 2041 RVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCP 2100
Query: 2101 TEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLSLKIPE 2160
TEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLSLKIPE
Sbjct: 2101 TEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLSLKIPE 2160
Query: 2161 ISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQF 2220
ISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQF
Sbjct: 2161 ISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQF 2220
Query: 2221 TVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDR 2280
TVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDR
Sbjct: 2221 TVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDR 2280
Query: 2281 KDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVN 2340
KDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVN
Sbjct: 2281 KDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVN 2340
Query: 2341 QPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG 2400
QPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG
Sbjct: 2341 QPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG 2400
Query: 2401 THIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDG 2460
THIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDG
Sbjct: 2401 THIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDG 2460
Query: 2461 PSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLH 2520
PSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLH
Sbjct: 2461 PSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLH 2520
Query: 2521 ETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNN 2580
ETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNN
Sbjct: 2521 ETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNN 2580
Query: 2581 MLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2639
MLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP
Sbjct: 2581 MLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2639
>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
Length = 2647
Score = 5378 bits (13950), Expect = 0.0
Identities = 2639/2647 (99%), Positives = 2639/2647 (99%), Gaps = 8/2647 (0%)
Query: 1 MSSSHSRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCV 60
MSSSHSRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCV
Sbjct: 1 MSSSHSRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCV 60
Query: 61 SKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIK 120
SKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIK
Sbjct: 61 SKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIK 120
Query: 121 LVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL 180
LVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL
Sbjct: 121 LVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL 180
Query: 181 PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQ 240
PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQ
Sbjct: 181 PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQ 240
Query: 241 VITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKK 300
VITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKK
Sbjct: 241 VITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKK 300
Query: 301 RAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLF 360
RAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLF
Sbjct: 301 RAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLF 360
Query: 361 AGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVI 420
AGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVI
Sbjct: 361 AGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVI 420
Query: 421 QDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNP 480
QDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNP
Sbjct: 421 QDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNP 480
Query: 481 SACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGF 540
SACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGF
Sbjct: 481 SACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGF 540
Query: 541 EYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVE 600
EYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVE
Sbjct: 541 EYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVE 600
Query: 601 AIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFM 660
AIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFM
Sbjct: 601 AIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFM 660
Query: 661 ADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVE 720
ADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVE
Sbjct: 661 ADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVE 720
Query: 721 ALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVA 780
ALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVA
Sbjct: 721 ALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVA 780
Query: 781 KTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTP 840
KTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTP
Sbjct: 781 KTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTP 840
Query: 841 RGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAK 900
RGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAK
Sbjct: 841 RGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAK 900
Query: 901 AAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSP 960
AAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSP
Sbjct: 901 AAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSP 960
Query: 961 FSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKV 1020
FSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKV
Sbjct: 961 FSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKV 1020
Query: 1021 EPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGG 1080
EPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGG
Sbjct: 1021 EPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGG 1080
Query: 1081 SAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILF 1140
SAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILF
Sbjct: 1081 SAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILF 1140
Query: 1141 ADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSE 1200
ADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSE
Sbjct: 1141 ADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSE 1200
Query: 1201 AGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQC 1260
AGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQC
Sbjct: 1201 AGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQC 1260
Query: 1261 YGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVE 1320
YGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVE
Sbjct: 1261 YGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVE 1320
Query: 1321 YTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVET 1380
YTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVET
Sbjct: 1321 YTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVET 1380
Query: 1381 RGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKV 1440
RGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKV
Sbjct: 1381 RGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKV 1440
Query: 1441 PVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVV 1500
PVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVV
Sbjct: 1441 PVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVV 1500
Query: 1501 DNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGV 1560
DNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGV
Sbjct: 1501 DNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGV 1560
Query: 1561 PASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILI 1620
PASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILI
Sbjct: 1561 PASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILI 1620
Query: 1621 KYGGDEIPFSPYRVRAVPTGDASKCTVT--------GAGIGPTIQIGEETVITVDTKAAG 1672
KYGGDEIPFSPYRVRAVPTGDASKCTVT GAGIGPTIQIGEETVITVDTKAAG
Sbjct: 1621 KYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAG 1680
Query: 1673 KGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTA 1732
KGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTA
Sbjct: 1681 KGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTA 1740
Query: 1733 LAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIK 1792
LAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIK
Sbjct: 1741 LAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIK 1800
Query: 1793 KGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1852
KGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV
Sbjct: 1801 KGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1860
Query: 1853 DYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTC 1912
DYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTC
Sbjct: 1861 DYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTC 1920
Query: 1913 SVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDL 1972
SVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDL
Sbjct: 1921 SVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDL 1980
Query: 1973 SLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2032
SLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVIS
Sbjct: 1981 SLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2040
Query: 2033 QSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDG 2092
QSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDG
Sbjct: 2041 QSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDG 2100
Query: 2093 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHC 2152
TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHC
Sbjct: 2101 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHC 2160
Query: 2153 DLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQH 2212
DLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQH
Sbjct: 2161 DLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQH 2220
Query: 2213 VPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSK 2272
VPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSK
Sbjct: 2221 VPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSK 2280
Query: 2273 AEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSL 2332
AEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSL
Sbjct: 2281 AEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSL 2340
Query: 2333 QESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVY 2392
QESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVY
Sbjct: 2341 QESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVY 2400
Query: 2393 LIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAG 2452
LIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAG
Sbjct: 2401 LIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAG 2460
Query: 2453 ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPR 2512
ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPR
Sbjct: 2461 ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPR 2520
Query: 2513 LVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTV 2572
LVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTV
Sbjct: 2521 LVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTV 2580
Query: 2573 DCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGS 2632
DCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGS
Sbjct: 2581 DCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGS 2640
Query: 2633 PYRVVVP 2639
PYRVVVP
Sbjct: 2641 PYRVVVP 2647
>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
sapiens]
Length = 2602
Score = 3802 bits (9860), Expect = 0.0
Identities = 1827/2613 (69%), Positives = 2164/2613 (82%), Gaps = 12/2613 (0%)
Query: 28 MPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQK 87
MP TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV+KRI NLQTDLSDGLRLIALLEVLSQK
Sbjct: 1 MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQK 60
Query: 88 KMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILH 147
+M+RK++QRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGL+WTLILH
Sbjct: 61 RMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILH 120
Query: 148 YSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAP 207
YSISMP+W++E D++AKKQTPKQRLLGWIQNK+P LPITNF+++WQ G+ALGALVDSCAP
Sbjct: 121 YSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAP 180
Query: 208 GLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKA 267
GLCPDW+SWD KPV NAREAMQQADDWLG+PQVITPEEI+ P+VDEHSVMTYLSQFPKA
Sbjct: 181 GLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKA 240
Query: 268 KLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQ 327
KLKPGAPL+PKLNPKKARAYG GIEPTGNMVK+ A+FTV+T SAGQG+V+V+VEDP G++
Sbjct: 241 KLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNK 300
Query: 328 EEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQ 387
EEA+VT ++DKN+T+SV Y+P+VTG HKVTVLFAGQHI+KSPFEV VDK+QGDASKVTA+
Sbjct: 301 EEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAK 360
Query: 388 GPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEARGDSTYRCSYQ 447
GPGLE GNIANK TYF+I+TAGAG G++ V ++DP G K TVE +E +G+ YRC Y+
Sbjct: 361 GPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYK 419
Query: 448 PTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYT 507
P G H V + FAG IP+SP+ V VG+ACNP+ACRA GRGLQPKGVR++ET DFKV T
Sbjct: 420 PMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDT 479
Query: 508 KGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPF 566
K AGSGEL VT+KGPKG EE VKQKD DGVY FEYYP PG Y + ITWGG +I +SPF
Sbjct: 480 KAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPF 539
Query: 567 EVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDK 626
EV+VG E G QKVRAWGPGL GG+VG+SADFVVE+IG +VG+LGF++EGPSQAKIE +D+
Sbjct: 540 EVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQ 599
Query: 627 GDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTG 686
DGSCDV+YWP+E GEYAVH++C+ EDI+ SP+MA I A ++PD V+A GPGLEK+G
Sbjct: 600 NDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSG 659
Query: 687 VAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALVKDNGNGTYSCSYVPRKPVKHTAM 746
VN AEFTVD K GKAPL++ QD EG ++ +K+ +GTY+CSY P K +KHT
Sbjct: 660 CIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIA 719
Query: 747 VSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSI 806
V WGGV+IP+SP+RVN+G GSHP KVKV+GPGV ++GLKA+EPT+FTVDC EAG+GDVS+
Sbjct: 720 VVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSV 779
Query: 807 GIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKV 866
GIKC V+ E D+DFDII N NDTFTVKY P AG YTI VLFA Q P SP RVKV
Sbjct: 780 GIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKV 839
Query: 867 EPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGLTKGDAVRDVDII 926
+PSHDASKVKAEGPGLS+ GVE GKPTHFTV K AGK L+VQF+ GDAV+D+DII
Sbjct: 840 DPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDII 899
Query: 927 DHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVG 986
D++D ++TVKYTP QQG + V VTYGGDPIPKSPF+V V+ LDLSKIK++GL +V+VG
Sbjct: 900 DNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVG 959
Query: 987 KDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVEVT 1046
KDQEFTV ++GAGGQGK+ I+ PS VPC V P G +NS +F+PREEG Y V+VT
Sbjct: 960 KDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVT 1019
Query: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
YDG PVPGSP+ +EA P PSKVKA GPGL+GG G PA FTIDTKGAGTGGLGLTVEG
Sbjct: 1020 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG 1079
Query: 1107 PCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCS 1166
PCEA++EC DNGDGTCSVSY+PT+PG+Y +NILF + HIPGSPFKA + FD SKV S
Sbjct: 1080 PCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVAS 1139
Query: 1167 GPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCP 1226
GPGLE GE G VDCS AG L +E S++G AEV IQ++ DGT+ +TY+PL
Sbjct: 1140 GPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTA 1199
Query: 1227 GAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALT 1286
G YT+T+KYGG+ VP+FP++++VEPAVDTS ++ +GPGIEG+ VFREATT+F+VD+R LT
Sbjct: 1200 GMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLT 1259
Query: 1287 QTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQ 1346
Q GG H+KA +ANPSG TE +V D DG Y+VEYTP+E+GLH V+VTYD P+P+SPF+
Sbjct: 1260 QVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFK 1319
Query: 1347 VPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNK 1406
V VTEGC PSRV+ GPG++ TNKPN FTV TRGAG GGLG+ VEGPSE+K++C DNK
Sbjct: 1320 VAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNK 1379
Query: 1407 DGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRAN 1466
DGSCS EYIP+ G Y +N+TYGG +PGSPF+VPV DV D SKVK +GPGL G VRA
Sbjct: 1380 DGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSG-VRAR 1438
Query: 1467 LPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYG 1526
+ QSF VD+SKAG+APL+V+V GP+GLVEPV+VVDN DGT TV Y PS+EGPY +SV Y
Sbjct: 1439 VLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYA 1498
Query: 1527 DEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITD 1586
DEE+PRSPFKVKVLPT+DASKV ASGPGL++ GVPASLPV+F IDA+DAGEGLLAVQITD
Sbjct: 1499 DEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITD 1558
Query: 1587 PEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCT 1646
EGKPK+ + DN DGTY V Y+PD TGRY I + YGGD+IP SPYR+RA TGDASKC
Sbjct: 1559 QEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCL 1618
Query: 1647 VTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTA 1706
TG GI T++ GEE VD K AGKGKVTCTV TPDG+E + DV+ENEDGT+DIFYTA
Sbjct: 1619 ATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTA 1678
Query: 1707 PQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPE 1766
+PG YVI VRFGG +PNSPF V A G+ +V+ AP G + W E
Sbjct: 1679 AKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEE-------AP-VNACPPGFRPWVTE 1730
Query: 1767 RPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAP 1826
V V+ ++ +PFDLVIPF ++KGEITGEV MPSGK A P I DNKDGTVTVRYAP
Sbjct: 1731 EAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAP 1790
Query: 1827 SEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAG 1886
+E GLHEM I+Y HIP SPLQFYV+Y N G V+AYGPGL +GV NK ATFT+ T+DAG
Sbjct: 1791 TEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAG 1850
Query: 1887 EGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTG 1946
EGGL LAIEGPSKAEISC DN+DGTC+V+YLP LPGDYSILVKYN++H+PGSPFTA++T
Sbjct: 1851 EGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKIT- 1909
Query: 1947 DDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPK 2006
DDS R S +K+GSAAD ++ISETDLS LTA++ PSGR+EPCLLKRL N H+GISF+P+
Sbjct: 1910 DDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPR 1969
Query: 2007 ETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRD 2066
E GEHLV +KKNG HVA+SP+ +++ QSEIGDA R +V G+GL EG TFE ++FI+DTRD
Sbjct: 1970 EVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRD 2029
Query: 2067 AGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV 2126
AGYGG+SL++EGPSKVDI TEDLEDGTC+V+Y PT PG YI++ KFAD+HVPGSPF+VK+
Sbjct: 2030 AGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKI 2089
Query: 2127 TGEGRVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGE 2186
+GEGRVKESITR RAPSVA VGS CDL+LKIPEI+ DM+A VTSPSG+ EAEIV
Sbjct: 2090 SGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMG 2149
Query: 2187 NHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAG 2246
+++C+RFVP EMG HTVSVKY+GQHV GSPFQFTVGPLGEGGAHKVRAGGPGLER EAG
Sbjct: 2150 KNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAG 2209
Query: 2247 VPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEE 2306
VPAEFSIWTREAGAGGL+IAVEGPSKAEI+F+D K+GSCGV+Y+ QEPG+YEVS+KFN+E
Sbjct: 2210 VPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE 2269
Query: 2307 HIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGA 2366
HIP+SP++VPV +PS DARRLTV SLQESGLKVNQPASFA+ LNGAKG IDAKVHSPSGA
Sbjct: 2270 HIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGA 2329
Query: 2367 LEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSA 2426
+EEC+V+E++ DKYAVRFIP ENGV+ IDVKFNG+H+ GSPFK+RVGEPG G+P LVSA
Sbjct: 2330 VEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSA 2389
Query: 2427 YGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGS 2486
YG GLEGG TG +EF +NT+ AG G LSVTI+GPSKVKMDCQE PEGY+V YTPMAPG+
Sbjct: 2390 YGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGN 2449
Query: 2487 YLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGP 2546
YLIS+KYGGP HI GSPFKAKVTG RLVS S +ETSS+ V+S+T+++ + A
Sbjct: 2450 YLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKAS 2509
Query: 2547 ADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLY 2606
+DASKV +KG GLSKA+VGQKSSF VDCSKAG+NMLL+GVHGP TPCEE+ +KHVG++ Y
Sbjct: 2510 SDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQY 2569
Query: 2607 SVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2639
+V+Y++K++G+Y L VKWG+EHIPGSP+ V VP
Sbjct: 2570 NVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2602
>gi|116805322 gamma filamin isoform a [Homo sapiens]
Length = 2725
Score = 3331 bits (8637), Expect = 0.0
Identities = 1684/2660 (63%), Positives = 2003/2660 (75%), Gaps = 97/2660 (3%)
Query: 6 SRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIA 65
+ +G S AG G D EMP+TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV KR+
Sbjct: 3 NNSGYSDAGLGLGDETD----EMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLT 58
Query: 66 NLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSID 125
+LQ DLSDGLRLIALLEVLSQK+M+RK + RP FRQM+LENVSVALEFL+RE IKLVSID
Sbjct: 59 DLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSID 118
Query: 126 SKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPI 185
SKAIVDGNLKLILGLIWTLILHYSISMPMW++E+DE+A+KQTPKQRLLGWIQNK+PQLPI
Sbjct: 119 SKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPI 178
Query: 186 TNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPE 245
TNF+RDWQ G+ALGALVD+CAPGLCPDW++WD ++PV NAREAMQQADDWLG+PQVI PE
Sbjct: 179 TNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPE 238
Query: 246 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPK-LNPKKARAYGPGIEPTGNMVKKRAEF 304
EIVDPNVDEHSVMTYLSQFPKAKLKPGAP+R K LNPKKA AYGPGIEP GN V + A F
Sbjct: 239 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHF 298
Query: 305 TVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQH 364
TV+T AG GEVLVY+EDP GH EEAKV NNDK+RT++V YVP+V G HKVTVLFAGQ+
Sbjct: 299 TVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQN 358
Query: 365 IAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPM 424
I +SPFEV V + GDA+KV+A+GPGLEP GN+ANK TYF+I+TAGAGTG+V VVI DP
Sbjct: 359 IERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQ 418
Query: 425 GQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACR 484
G++ TVE LE +GDST+RC+Y+P MEG HTVHV FAG PI RSP+ V V +ACNP+ACR
Sbjct: 419 GRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACR 478
Query: 485 AVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYY 543
A GRGLQPKGVRVKE ADFKV+TKGAGSGELKVTVKGPKG EE VK ++ GDGV+ EYY
Sbjct: 479 ASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYY 538
Query: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
P+VPG Y+VTITWGG I RSPFEV+V E G QKVRAWGPGLE G VGKSADFVVEAIG
Sbjct: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIG 598
Query: 604 DDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADI 663
+VGTLGFS+EGPSQAKIECDDKGDGSCDVRYWP E GEYAVHV+C+ EDIR SPF+A I
Sbjct: 599 TEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHI 658
Query: 664 RDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALV 723
AP D PD+VKA GPGLE TG V+KPAEFT+DA+ GK L++ QD +GCP++ V
Sbjct: 659 LPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKV 718
Query: 724 KDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTG 783
NG+GT+ CSYVP KP+KHT ++SWGGV++P SPFRVNVG GSHP +VKVYGPGV KTG
Sbjct: 719 IPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTG 778
Query: 784 LKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGA 843
LKA+EPTYFTVDC+EAGQGDVSIGIKCAPGVVGPAEADIDFDII+NDNDTFTVKYTP GA
Sbjct: 779 LKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGA 838
Query: 844 GSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG 903
G YTIMVLFA+Q P SP +KV+PSHDASKVKAEGPGL+RTGVE+GKPTHFTV K AG
Sbjct: 839 GRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAG 898
Query: 904 KGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSV 963
K KLDVQF+G KG+ VRD +IID+HD +YTVKYT VQQG + V VTYGGDP+PKSPF V
Sbjct: 899 KAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVV 958
Query: 964 AVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPG 1023
V+P LDLSKIKV GL KV VG++Q F+V ++GAGGQG++ ++ PS +PCK+EPG
Sbjct: 959 NVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPG 1018
Query: 1024 LGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAG 1083
GA+ VR++P EEGPY+V++TYDG PVPGSPF +E V P PSKV A+GPGL+GG G
Sbjct: 1019 GGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVG 1078
Query: 1084 SPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADT 1143
+PA F+IDTKGAGTGGLGLTVEGPCEA++EC DNGDG+C+VSY+PTEPG+Y INILFA+
Sbjct: 1079 TPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEA 1138
Query: 1144 HIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGL 1203
HIPGSPFKA + P FD SKV+ SGPGLER GE F VDCS AG AELTIEI S+AG+
Sbjct: 1139 HIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGV 1198
Query: 1204 PAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGP 1263
AEV I ++ DGT+ ITY P PG YT+TIKYGG PVP FP+++ V+PAVDTSGV+ GP
Sbjct: 1199 KAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGP 1258
Query: 1264 GIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTP 1323
G+E GV RE TTEF+VDAR+LT TGG HV ARV NPSG T+TYV D GDG Y+V+YT
Sbjct: 1259 GVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTA 1318
Query: 1324 YEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGA 1383
YEEG+H V+V YD VP SPF+V VTEGCDP+RVR GPG++ G NK N+FTVETRGA
Sbjct: 1319 YEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGA 1378
Query: 1384 GTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVH 1443
GTGGLGLA+EGPSEAKMSC DNKDGSC+VEYIP+ G Y +N+T+GG +PGSPF+VPV
Sbjct: 1379 GTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVK 1438
Query: 1444 DVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNA 1503
DV D KVKCSGPGL G VRA +PQ+F VD S+AG APLQV V GP G+ EPV+V DN
Sbjct: 1439 DVVDPGKVKCSGPGLGAG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNG 1497
Query: 1504 DGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPAS 1563
DGT TV+Y P+ +GPY+++V Y D+EVPRSPFK+KVLP HDASKV+ASGPGLN +G+PAS
Sbjct: 1498 DGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPAS 1557
Query: 1564 LPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYG 1623
LPVEFTIDA+DAGEGLL VQI DPEGKPKK +I+DN DGTYTV+Y+PD++GRYTI IKYG
Sbjct: 1558 LPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYG 1617
Query: 1624 GDEIPFSPYRVRAVPTGDASKCTVT--------GAGIGPTIQIGEETVITVDTKAAGKGK 1675
GDEIP+SP+R+ A+PTGDASKC VT GA +GP IQIG+ETVITVD KAAG+GK
Sbjct: 1618 GDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGK 1677
Query: 1676 VTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTAL-- 1733
VTCTV TPDG+E+DVDVVEN DGTFDI+YTAP+PGKYVI +RFGGEH+PNSPF V A
Sbjct: 1678 VTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDP 1737
Query: 1734 --AGDQPSVQPPLRSQQLAPQYTYAQGGQQT-WAPERPLVGVNGLDVTSLRPFDLVIPFT 1790
++PS P LR P+ G + T WA E P+V V ++ + LRPF+LVIPF
Sbjct: 1738 LPHEEEPSEVPQLRQPYAPPR----PGARPTHWATEEPVVPVEPME-SMLRPFNLVIPFA 1792
Query: 1791 IKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQF 1850
++KGE+TGEVRMPSGK A+P ITDNKDGT+TVRYAP+E GLH+M I+YD HIPGSPLQF
Sbjct: 1793 VQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQF 1852
Query: 1851 YVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDG 1910
YVD +N HV+AYGPGL+HG+VNKPATFT+ TKDAGEGGLSLA+EGPSKAEI+C DN+DG
Sbjct: 1853 YVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDG 1912
Query: 1911 TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISET 1970
TC+VSYLP PGDYSI+V+++++H+PGSPFTA++TGDDSMR S L VG++ D+ + I+E+
Sbjct: 1913 TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITES 1972
Query: 1971 DLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVV 2030
DLS LTA++ PSG EEPCLLKRL N H+GISF PKE GEH+V V+K+G+HV +SP ++
Sbjct: 1973 DLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKIL 2032
Query: 2031 ISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLE 2090
+ SEIGDAS+VRV G+GL EGHTF+ AEFI+DTR+AGYGGL LSIEGPSKVDIN ED+E
Sbjct: 2033 VGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDME 2092
Query: 2091 DGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGS 2150
DGTC+VTYCPTEPG YIINIKFAD+HVPGSPF+VKVTGEGR+KESITRRR+APS+A +GS
Sbjct: 2093 DGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGS 2152
Query: 2151 HCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKG 2210
CDL+LKIP Q ++AQ T + T + E V V+
Sbjct: 2153 TCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGET-KREVRVEEST 2211
Query: 2211 QHVPGSPFQFTVGPLGEGGAHKVRAGGPG-LERAEAGVPAEFSIWTREAGAGGLAIAVEG 2269
Q V G PF G + R G G + R + G EA + + V
Sbjct: 2212 Q-VGGDPFPAVFGDF----LGRERLGSFGSITRQQEG----------EASSQDMTAQVTS 2256
Query: 2270 PS-KAEIS-FEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVAS-PSGDARR 2326
PS K E + + +D + V +V QE G + V+VK+ +H+P SPF V G A +
Sbjct: 2257 PSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHK 2316
Query: 2327 LTVSSLQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFI 2385
+ PA F++ + G + V PS A E + V ++
Sbjct: 2317 VRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKA--EIAFEDRKDGSCGVSYV 2374
Query: 2386 PRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVN 2445
+E G Y + +KFN HIP SPF + V D ++ G PA F V
Sbjct: 2375 VQEPGDYEVSIKFNDEHIPDSPFVVPVA--SLSDDARRLTVTSLQETGLKVNQPASFAVQ 2432
Query: 2446 TSNAGAGALSVTIDGPSKVKMDC---QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGS 2502
N G + + PS +C + + + + + P G + I +K+ G HI GS
Sbjct: 2433 L-NGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGA-HIPGS 2490
Query: 2503 PFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKA 2562
PFK +V E S Q G PG V A G GL
Sbjct: 2491 PFKIRV-----------GEQS--------------QAGDPG-------LVSAYGPGLEGG 2518
Query: 2563 YVGQKSSFTVDCSKAGNNMLLVGVHGP---RTPCEEILVKHVGSRLYSVSYLLKDKGEYT 2619
G S F V+ AG+ L V + GP + C E HV V+Y G Y
Sbjct: 2519 TTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHV------VTYTPMAPGNYL 2572
Query: 2620 LVVKW-GDEHIPGSPYRVVV 2638
+ +K+ G +HI GSP++ V
Sbjct: 2573 IAIKYGGPQHIVGSPFKAKV 2592
Score = 1590 bits (4117), Expect = 0.0
Identities = 967/2450 (39%), Positives = 1351/2450 (55%), Gaps = 194/2450 (7%)
Query: 283 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTF 342
K A GPG+EP GN+ K F + T AG G+V V + DP G ++ +V + + TF
Sbjct: 377 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTF 436
Query: 343 SVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTT 402
Y P + G H V V FAG I +SPF V+V ++ + + A G GL+P G +
Sbjct: 437 RCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEAC-NPNACRASGRGLQPKGVRVKEVA 495
Query: 403 YFEIFTAGAGTGEVEVVIQDPMGQKGTVEP-QLEARGDSTYRCSYQPTMEGVHTVHVTFA 461
F++FT GAG+GE++V ++ P KGT EP ++ GD + C Y P + G + V +T+
Sbjct: 496 DFKVFTKGAGSGELKVTVKGP---KGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWG 552
Query: 462 GVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKG 521
G IPRSP+ V V RA G GL+ +V ++ADF V G G L +++G
Sbjct: 553 GYAIPRSPFEVQVSPEAGVQKVRAWGPGLETG--QVGKSADFVVEAIGTEVGTLGFSIEG 610
Query: 522 PKGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKV---GTECGNQK 578
P + +++ D GDG Y+P PG Y V + ++I SPF + +C K
Sbjct: 611 PS-QAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDK 669
Query: 579 VRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECD--DKGDGSCDVR 634
V+A+GPGLE G +V K A+F ++A G L + I+ GDG+
Sbjct: 670 VKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCS 729
Query: 635 YWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAE 694
Y P + ++ + + ++ SPF ++ + HP+RVK GPG+EKTG+ N+P
Sbjct: 730 YVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGS---HPERVKVYGPGVEKTGLKANEPTY 786
Query: 695 FTVDAKHGGKAPLRVQVQDNEGC--PVEALVK----DNGNGTYSCSYVPRKPVKHTAMVS 748
FTVD G+ + + ++ G P EA + N N T++ Y P ++T MV
Sbjct: 787 FTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVL 846
Query: 749 WGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGI 808
+ IP SPF + V +KVK GPG+ +TG++ +PT+FTV AG+ + +
Sbjct: 847 FANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQF 906
Query: 809 KCAPGVVGPAEADI--DFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKV 866
G A+ ++ DF+II N + ++TVKYT G+ + V + P SP V V
Sbjct: 907 ------AGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
Query: 867 EPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG-KGKLDVQFSGLTKGDAVRDVDI 925
P D SK+K +G + V +G+ F+VN + AG +G+LDV+ + ++ ++
Sbjct: 961 APPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEP 1017
Query: 926 IDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVD- 984
+ V+Y P ++GP V++TY G P+P SPF+V D SK+ G G K
Sbjct: 1018 GGGAE-AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL 1076
Query: 985 VGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVE 1044
VG F++ +KGAG G + + GP A + C+ G + V +LP E G Y +
Sbjct: 1077 VGTPAPFSIDTKGAG-TGGLGLTVEGPCEAKIECQDN---GDGSCAVSYLPTEPGEYTIN 1132
Query: 1045 VTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTV 1104
+ + +PGSPF PSKV+A GPGL+ G G A FT+D AG L + +
Sbjct: 1133 ILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEI 1192
Query: 1105 EGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASK 1162
+ E L +N DGT ++Y P PG Y I I + +P P + HV P D S
Sbjct: 1193 LSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSG 1252
Query: 1163 VKCSGPGLE-RATAGEVG-QFQVDCSS---AGSAELTIEICSEAGLPAEVYIQDHGDGTH 1217
VK SGPG+E EV +F VD S G +T + + +G + Y+ D+GDGT+
Sbjct: 1253 VKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTY 1312
Query: 1218 TITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTE 1277
+ Y G + V + Y VP P ++ V D + V+ +GPG+EG G+ +A
Sbjct: 1313 RVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEG-GLVNKAN-R 1370
Query: 1278 FSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDG 1337
F+V+ R TGG + + PS + +D DG VEY P+ G + V++T+ G
Sbjct: 1371 FTVETRG-AGTGG--LGLAIEGPSE--AKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGG 1425
Query: 1338 SPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNK-PNKFTVETRGAGTGGLGLAVEGPS 1396
P+P SPF+VPV + DP +V+ GPG+ +G + P FTV+ AG L +AV GP+
Sbjct: 1426 RPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPT 1485
Query: 1397 EAK--MSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCS 1454
+ DN DG+ +V Y P G Y++ V Y +VP SPFK+ V DASKV+ S
Sbjct: 1486 GVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRAS 1545
Query: 1455 GPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPS 1514
GPGL+ + A+LP F +D AG L V++ P+G + ++ DN DGT TV+Y+P
Sbjct: 1546 GPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPD 1605
Query: 1515 REGPYSISVLYGDEEVPRSPFKVKVLPTHDASK----VKASGPGLNTTGVPA---SLPVE 1567
G Y+I++ YG +E+P SPF++ LPT DASK V G GL P
Sbjct: 1606 MSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETV 1665
Query: 1568 FTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEI 1627
T+DAK AGEG + ++ P+G + +NHDGT+ + Y G+Y I I++GG+ I
Sbjct: 1666 ITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHI 1725
Query: 1628 PFSPYRVRA---VPTGDASK--------CTVTGAGIGPTIQIGEETVITVDTK------- 1669
P SP+ V A +P + G PT EE V+ V+
Sbjct: 1726 PNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPF 1785
Query: 1670 ------AAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHV 1723
A KG++T V P G ++ +N+DGT + Y + G + + +++ G H+
Sbjct: 1786 NLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHI 1845
Query: 1724 PNSPFQ--VTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLR 1781
P SP Q V A+ S P G++ V
Sbjct: 1846 PGSPLQFYVDAINSRHVSAYGP---------------------------GLSHGMVNKPA 1878
Query: 1782 PFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNM 1841
F +V T GE + + A+ T DNKDGT TV Y P+ G + + +R+D+
Sbjct: 1879 TFTIV---TKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDK 1935
Query: 1842 HIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAE 1901
HIPGSP + + + G + V K + D + L+ +I PS E
Sbjct: 1936 HIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLK-----ITESDLSQ--LTASIRAPSGNE 1988
Query: 1902 ISCTDNQ--DGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGS 1959
C + + +S+ P G++ + V+ + +HV SPF V + S ++V
Sbjct: 1989 EPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWG 2048
Query: 1960 ----------AADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETG 2009
A+ ++ L ++ PS + C + + +G +++ P E G
Sbjct: 2049 KGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINC--EDMEDGTCKVTYCPTEPG 2106
Query: 2010 EHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGY 2069
+++++K +HV SP V +V+G+G + +
Sbjct: 2107 TYIINIKFADKHVPGSPFTV-------------KVTGEGRMKESITRRRQAPSIATIGST 2153
Query: 2070 GGLSLSIEGP-----------SKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQ-HV 2117
L+L I G ++ + T R T G ++ + V
Sbjct: 2154 CDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQV 2213
Query: 2118 PGSPFSVKVTGEGRVKE------SITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVT 2171
G PF V G+ +E SITR++ E S QDMTAQVT
Sbjct: 2214 GGDPFPA-VFGDFLGRERLGSFGSITRQQEG-----------------EASSQDMTAQVT 2255
Query: 2172 SPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAH 2231
SPSGK AEIVEGE+ Y +RFVP EMG HTV+VKY+GQHVPGSPFQFTVGPLGEGGAH
Sbjct: 2256 SPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAH 2315
Query: 2232 KVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVV 2291
KVRAGG GLER AGVPAEFSIWTREAGAGGL+IAVEGPSKAEI+FEDRKDGSCGV+YVV
Sbjct: 2316 KVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVV 2375
Query: 2292 QEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNG 2351
QEPGDYEVS+KFN+EHIPDSPFVVPVAS S DARRLTV+SLQE+GLKVNQPASFAV LNG
Sbjct: 2376 QEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNG 2435
Query: 2352 AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIR 2411
A+G IDA+VH+PSGA+EECYV+E+D DK+ +RFIP ENGV+ IDVKFNG HIPGSPFKIR
Sbjct: 2436 ARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIR 2495
Query: 2412 VGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQEC 2471
VGE GDPGLVSAYG GLEGG TG +EF+VNT NAG+GALSVTIDGPSKV++DC+EC
Sbjct: 2496 VGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCREC 2555
Query: 2472 PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLT 2531
PEG+ VTYTPMAPG+YLI+IKYGGP HI GSPFKAKVTGPRL HSLHETS+V V+++T
Sbjct: 2556 PEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVT 2615
Query: 2532 KATCA--PQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGP 2589
K++ + + + +DASKVV +G GLS+A+VGQK+SFTVDCSKAG NM++VGVHGP
Sbjct: 2616 KSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGP 2675
Query: 2590 RTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2639
+TPCEE+ VKH+G+R+Y+V+Y +K+KG+Y L+VKWGDE +PGSP++V VP
Sbjct: 2676 KTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2725
>gi|188595687 gamma filamin isoform b [Homo sapiens]
Length = 2692
Score = 3311 bits (8586), Expect = 0.0
Identities = 1674/2655 (63%), Positives = 1989/2655 (74%), Gaps = 120/2655 (4%)
Query: 6 SRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIA 65
+ +G S AG G D EMP+TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV KR+
Sbjct: 3 NNSGYSDAGLGLGDETD----EMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLT 58
Query: 66 NLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSID 125
+LQ DLSDGLRLIALLEVLSQK+M+RK + RP FRQM+LENVSVALEFL+RE IKLVSID
Sbjct: 59 DLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSID 118
Query: 126 SKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPI 185
SKAIVDGNLKLILGLIWTLILHYSISMPMW++E+DE+A+KQTPKQRLLGWIQNK+PQLPI
Sbjct: 119 SKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPI 178
Query: 186 TNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPE 245
TNF+RDWQ G+ALGALVD+CAPGLCPDW++WD ++PV NAREAMQQADDWLG+PQVI PE
Sbjct: 179 TNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPE 238
Query: 246 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPK-LNPKKARAYGPGIEPTGNMVKKRAEF 304
EIVDPNVDEHSVMTYLSQFPKAKLKPGAP+R K LNPKKA AYGPGIEP GN V + A F
Sbjct: 239 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHF 298
Query: 305 TVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQH 364
TV+T AG GEVLVY+EDP GH EEAKV NNDK+RT++V YVP+V G HKVTVLFAGQ+
Sbjct: 299 TVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQN 358
Query: 365 IAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPM 424
I +SPFEV V + GDA+KV+A+GPGLEP GN+ANK TYF+I+TAGAGTG+V VVI DP
Sbjct: 359 IERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQ 418
Query: 425 GQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACR 484
G++ TVE LE +GDST+RC+Y+P MEG HTVHV FAG PI RSP+ V V +ACNP+ACR
Sbjct: 419 GRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACR 478
Query: 485 AVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYY 543
A GRGLQPKGVRVKE ADFKV+TKGAGSGELKVTVKGPKG EE VK ++ GDGV+ EYY
Sbjct: 479 ASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYY 538
Query: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
P+VPG Y+VTITWGG I RSPFEV+V E G QKVRAWGPGLE G VGKSADFVVEAIG
Sbjct: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIG 598
Query: 604 DDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADI 663
+VGTLGFS+EGPSQAKIECDDKGDGSCDVRYWP E GEYAVHV+C+ EDIR SPF+A I
Sbjct: 599 TEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHI 658
Query: 664 RDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALV 723
AP D PD+VKA GPGLE TG V+KPAEFT+DA+ GK L++ QD +GCP++ V
Sbjct: 659 LPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKV 718
Query: 724 KDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTG 783
NG+GT+ CSYVP KP+KHT ++SWGGV++P SPFRVNVG GSHP +VKVYGPGV KTG
Sbjct: 719 IPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTG 778
Query: 784 LKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGA 843
LKA+EPTYFTVDC+EAGQGDVSIGIKCAPGVVGPAEADIDFDII+NDNDTFTVKYTP GA
Sbjct: 779 LKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGA 838
Query: 844 GSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG 903
G YTIMVLFA+Q P SP +KV+PSHDASKVKAEGPGL+RTGVE+GKPTHFTV K AG
Sbjct: 839 GRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAG 898
Query: 904 KGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSV 963
K KLDVQF+G KG+ VRD +IID+HD +YTVKYT VQQG + V VTYGGDP+PKSPF V
Sbjct: 899 KAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVV 958
Query: 964 AVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPG 1023
V+P LDLSKIKV GL KV VG++Q F+V ++GAGGQG++ ++ PS +PCK+EPG
Sbjct: 959 NVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPG 1018
Query: 1024 LGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAG 1083
GA+ VR++P EEGPY+V++TYDG PVPGSPF +E V P PSKV A+GPGL+GG G
Sbjct: 1019 GGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVG 1078
Query: 1084 SPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADT 1143
+PA F+IDTKGAGTGGLGLTVEGPCEA++EC DNGDG+C+VSY+PTEPG+Y INILFA+
Sbjct: 1079 TPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEA 1138
Query: 1144 HIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGL 1203
HIPGSPFKA + P FD SKV+ SGPGLER GE F VDCS AG AELTIEI S+AG+
Sbjct: 1139 HIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGV 1198
Query: 1204 PAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGP 1263
AEV I ++ DGT+ ITY P PG YT+TIKYGG PVP FP+++ V+PAVDTSGV+ GP
Sbjct: 1199 KAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGP 1258
Query: 1264 GIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTP 1323
G+E GV RE TTEF+VDAR+LT TGG HV ARV NPSG T+TYV D GDG Y+V+YT
Sbjct: 1259 GVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTA 1318
Query: 1324 YEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGA 1383
YEEG+H V+V YD VP SPF+V VTEGCDP+RVR GPG++ G NK N+FTVETRGA
Sbjct: 1319 YEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGA 1378
Query: 1384 GTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVH 1443
GTGGLGLA+EGPSEAKMSC DNKDGSC+VEYIP+ G Y +N+T+GG +PGSPF+VPV
Sbjct: 1379 GTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVK 1438
Query: 1444 DVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNA 1503
DV D KVKCSGPGL G VRA +PQ+F VD S+AG APLQV V GP G+ EPV+V DN
Sbjct: 1439 DVVDPGKVKCSGPGLGAG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNG 1497
Query: 1504 DGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPAS 1563
DGT TV+Y P+ +GPY+++V Y D+EVPRSPFK+KVLP HDASKV+ASGPGLN +G+PAS
Sbjct: 1498 DGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPAS 1557
Query: 1564 LPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYG 1623
LPVEFTIDA+DAGEGLL VQI DPEGKPKK +I+DN DGTYTV+Y+PD++GRYTI IKYG
Sbjct: 1558 LPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYG 1617
Query: 1624 GDEIPFSPYRVRAVPTGDASKCTVT--------GAGIGPTIQIGEETVITVDTKAAGKGK 1675
GDEIP+SP+R+ A+PTGDASKC VT GA +GP IQIG+ETVITVD KAAG+GK
Sbjct: 1618 GDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGK 1677
Query: 1676 VTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAG 1735
VTCTV TPDG+E+DVDVVEN DGTFDI+YTAP+PGKYVI +RFGGEH+PNSPF V
Sbjct: 1678 VTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL---- 1733
Query: 1736 DQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGE 1795
A E P+V V ++ + LRPF+LVIPF ++KGE
Sbjct: 1734 ----------------------------ATEEPVVPVEPME-SMLRPFNLVIPFAVQKGE 1764
Query: 1796 ITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYV 1855
+TGEVRMPSGK A+P ITDNKDGT+TVRYAP+E GLH+M I+YD HIPGSPLQFYVD +
Sbjct: 1765 LTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAI 1824
Query: 1856 NCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVS 1915
N HV+AYGPGL+HG+VNKPATFT+ TKDAGEGGLSLA+EGPSKAEI+C DN+DGTC+VS
Sbjct: 1825 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVS 1884
Query: 1916 YLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLL 1975
YLP PGDYSI+V+++++H+PGSPFTA++TGDDSMR S L VG++ D+ + I+E+DLS L
Sbjct: 1885 YLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQL 1944
Query: 1976 TATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSE 2035
TA++ PSG EEPCLLKRL N H+GISF PKE GEH+V V+K+G+HV +SP +++ SE
Sbjct: 1945 TASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSE 2004
Query: 2036 IGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCR 2095
IGDAS+VRV G+GL EGHTF+ AEFI+DTR+AGYGGL LSIEGPSKVDIN ED+EDGTC+
Sbjct: 2005 IGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCK 2064
Query: 2096 VTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLS 2155
VTYCPTEPG YIINIKFAD+HVPGSPF+VKVTGEGR+KESITRRR+APS+A +GS CDL+
Sbjct: 2065 VTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLN 2124
Query: 2156 LKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPG 2215
LKIP Q ++AQ T + T + E V V+ Q V G
Sbjct: 2125 LKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGET-KREVRVEESTQ-VGG 2182
Query: 2216 SPFQFTVGPLGEGGAHKVRAGGPG-LERAEAGVPAEFSIWTREAGAGGLAIAVEGPS-KA 2273
PF G + R G G + R + G EA + + V PS K
Sbjct: 2183 DPFPAVFGDF----LGRERLGSFGSITRQQEG----------EASSQDMTAQVTSPSGKV 2228
Query: 2274 EIS-FEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVAS-PSGDARRLTVSS 2331
E + + +D + V +V QE G + V+VK+ +H+P SPF V G A ++
Sbjct: 2229 EAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGG 2288
Query: 2332 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENG 2390
PA F++ + G + V PS A E + V ++ +E G
Sbjct: 2289 TGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKA--EIAFEDRKDGSCGVSYVVQEPG 2346
Query: 2391 VYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAG 2450
Y + +KFN HIP SPF + V D ++ G PA F V N
Sbjct: 2347 DYEVSIKFNDEHIPDSPFVVPVA--SLSDDARRLTVTSLQETGLKVNQPASFAVQL-NGA 2403
Query: 2451 AGALSVTIDGPSKVKMDC---QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAK 2507
G + + PS +C + + + + + P G + I +K+ G HI GSPFK +
Sbjct: 2404 RGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGA-HIPGSPFKIR 2462
Query: 2508 VTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQK 2567
V E S Q G PG V A G GL G
Sbjct: 2463 V-----------GEQS--------------QAGDPG-------LVSAYGPGLEGGTTGVS 2490
Query: 2568 SSFTVDCSKAGNNMLLVGVHGP---RTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKW 2624
S F V+ AG+ L V + GP + C E HV V+Y G Y + +K+
Sbjct: 2491 SEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHV------VTYTPMAPGNYLIAIKY 2544
Query: 2625 -GDEHIPGSPYRVVV 2638
G +HI GSP++ V
Sbjct: 2545 GGPQHIVGSPFKAKV 2559
Score = 1589 bits (4114), Expect = 0.0
Identities = 963/2439 (39%), Positives = 1345/2439 (55%), Gaps = 205/2439 (8%)
Query: 283 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTF 342
K A GPG+EP GN+ K F + T AG G+V V + DP G ++ +V + + TF
Sbjct: 377 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTF 436
Query: 343 SVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTT 402
Y P + G H V V FAG I +SPF V+V ++ + + A G GL+P G +
Sbjct: 437 RCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEAC-NPNACRASGRGLQPKGVRVKEVA 495
Query: 403 YFEIFTAGAGTGEVEVVIQDPMGQKGTVEP-QLEARGDSTYRCSYQPTMEGVHTVHVTFA 461
F++FT GAG+GE++V ++ P KGT EP ++ GD + C Y P + G + V +T+
Sbjct: 496 DFKVFTKGAGSGELKVTVKGP---KGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWG 552
Query: 462 GVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKG 521
G IPRSP+ V V RA G GL+ +V ++ADF V G G L +++G
Sbjct: 553 GYAIPRSPFEVQVSPEAGVQKVRAWGPGLETG--QVGKSADFVVEAIGTEVGTLGFSIEG 610
Query: 522 PKGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKV---GTECGNQK 578
P + +++ D GDG Y+P PG Y V + ++I SPF + +C K
Sbjct: 611 PS-QAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDK 669
Query: 579 VRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECD--DKGDGSCDVR 634
V+A+GPGLE G +V K A+F ++A G L + I+ GDG+
Sbjct: 670 VKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCS 729
Query: 635 YWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAE 694
Y P + ++ + + ++ SPF ++ + HP+RVK GPG+EKTG+ N+P
Sbjct: 730 YVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGS---HPERVKVYGPGVEKTGLKANEPTY 786
Query: 695 FTVDAKHGGKAPLRVQVQDNEGC--PVEALVK----DNGNGTYSCSYVPRKPVKHTAMVS 748
FTVD G+ + + ++ G P EA + N N T++ Y P ++T MV
Sbjct: 787 FTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVL 846
Query: 749 WGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGI 808
+ IP SPF + V +KVK GPG+ +TG++ +PT+FTV AG+ + +
Sbjct: 847 FANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQF 906
Query: 809 KCAPGVVGPAEADI--DFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKV 866
G A+ ++ DF+II N + ++TVKYT G+ + V + P SP V V
Sbjct: 907 ------AGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
Query: 867 EPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG-KGKLDVQFSGLTKGDAVRDVDI 925
P D SK+K +G + V +G+ F+VN + AG +G+LDV+ + ++ ++
Sbjct: 961 APPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEP 1017
Query: 926 IDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVD- 984
+ V+Y P ++GP V++TY G P+P SPF+V D SK+ G G K
Sbjct: 1018 GGGAE-AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL 1076
Query: 985 VGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVE 1044
VG F++ +KGAG G + + GP A + C+ G + V +LP E G Y +
Sbjct: 1077 VGTPAPFSIDTKGAG-TGGLGLTVEGPCEAKIECQDN---GDGSCAVSYLPTEPGEYTIN 1132
Query: 1045 VTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTV 1104
+ + +PGSPF PSKV+A GPGL+ G G A FT+D AG L + +
Sbjct: 1133 ILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEI 1192
Query: 1105 EGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASK 1162
+ E L +N DGT ++Y P PG Y I I + +P P + HV P D S
Sbjct: 1193 LSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSG 1252
Query: 1163 VKCSGPGLE-RATAGEVG-QFQVDCSS---AGSAELTIEICSEAGLPAEVYIQDHGDGTH 1217
VK SGPG+E EV +F VD S G +T + + +G + Y+ D+GDGT+
Sbjct: 1253 VKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTY 1312
Query: 1218 TITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTE 1277
+ Y G + V + Y VP P ++ V D + V+ +GPG+EG G+ +A
Sbjct: 1313 RVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEG-GLVNKAN-R 1370
Query: 1278 FSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDG 1337
F+V+ R TGG + + PS + +D DG VEY P+ G + V++T+ G
Sbjct: 1371 FTVETRG-AGTGG--LGLAIEGPSE--AKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGG 1425
Query: 1338 SPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNK-PNKFTVETRGAGTGGLGLAVEGPS 1396
P+P SPF+VPV + DP +V+ GPG+ +G + P FTV+ AG L +AV GP+
Sbjct: 1426 RPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPT 1485
Query: 1397 EAK--MSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCS 1454
+ DN DG+ +V Y P G Y++ V Y +VP SPFK+ V DASKV+ S
Sbjct: 1486 GVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRAS 1545
Query: 1455 GPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPS 1514
GPGL+ + A+LP F +D AG L V++ P+G + ++ DN DGT TV+Y+P
Sbjct: 1546 GPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPD 1605
Query: 1515 REGPYSISVLYGDEEVPRSPFKVKVLPTHDASK----VKASGPGLNTTGVPA---SLPVE 1567
G Y+I++ YG +E+P SPF++ LPT DASK V G GL P
Sbjct: 1606 MSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETV 1665
Query: 1568 FTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEI 1627
T+DAK AGEG + ++ P+G + +NHDGT+ + Y G+Y I I++GG+ I
Sbjct: 1666 ITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHI 1725
Query: 1628 PFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTK-------------AAGKG 1674
P SP+ V A EE V+ V+ A KG
Sbjct: 1726 PNSPFHVLAT----------------------EEPVVPVEPMESMLRPFNLVIPFAVQKG 1763
Query: 1675 KVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQ--VTA 1732
++T V P G ++ +N+DGT + Y + G + + +++ G H+P SP Q V A
Sbjct: 1764 ELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDA 1823
Query: 1733 LAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIK 1792
+ S P G++ V F +V T
Sbjct: 1824 INSRHVSAYGP---------------------------GLSHGMVNKPATFTIV---TKD 1853
Query: 1793 KGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1852
GE + + A+ T DNKDGT TV Y P+ G + + +R+D+ HIPGSP +
Sbjct: 1854 AGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKI 1913
Query: 1853 DYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQ--DG 1910
+ + G + V K + D + L+ +I PS E C + +
Sbjct: 1914 TGDDSMRTSQLNVGTSTDVSLK-----ITESDLSQ--LTASIRAPSGNEEPCLLKRLPNR 1966
Query: 1911 TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGS----------A 1960
+S+ P G++ + V+ + +HV SPF V + S ++V
Sbjct: 1967 HIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQV 2026
Query: 1961 ADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQ 2020
A+ ++ L ++ PS + C + + +G +++ P E G +++++K +
Sbjct: 2027 AEFIVDTRNAGYGGLGLSIEGPSKVDINC--EDMEDGTCKVTYCPTEPGTYIINIKFADK 2084
Query: 2021 HVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGP- 2079
HV SP V +V+G+G + + L+L I G
Sbjct: 2085 HVPGSPFTV-------------KVTGEGRMKESITRRRQAPSIATIGSTCDLNLKIPGNW 2131
Query: 2080 ----------SKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQ-HVPGSPFSVKVTG 2128
++ + T R T G ++ + V G PF V G
Sbjct: 2132 FQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA-VFG 2190
Query: 2129 EGRVKE------SITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEI 2182
+ +E SITR++ E S QDMTAQVTSPSGK AEI
Sbjct: 2191 DFLGRERLGSFGSITRQQEG-----------------EASSQDMTAQVTSPSGKVEAAEI 2233
Query: 2183 VEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLER 2242
VEGE+ Y +RFVP EMG HTV+VKY+GQHVPGSPFQFTVGPLGEGGAHKVRAGG GLER
Sbjct: 2234 VEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLER 2293
Query: 2243 AEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVK 2302
AGVPAEFSIWTREAGAGGL+IAVEGPSKAEI+FEDRKDGSCGV+YVVQEPGDYEVS+K
Sbjct: 2294 GVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIK 2353
Query: 2303 FNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHS 2362
FN+EHIPDSPFVVPVAS S DARRLTV+SLQE+GLKVNQPASFAV LNGA+G IDA+VH+
Sbjct: 2354 FNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHT 2413
Query: 2363 PSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPG 2422
PSGA+EECYV+E+D DK+ +RFIP ENGV+ IDVKFNG HIPGSPFKIRVGE GDPG
Sbjct: 2414 PSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPG 2473
Query: 2423 LVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPM 2482
LVSAYG GLEGG TG +EF+VNT NAG+GALSVTIDGPSKV++DC+ECPEG+ VTYTPM
Sbjct: 2474 LVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPM 2533
Query: 2483 APGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCA--PQHG 2540
APG+YLI+IKYGGP HI GSPFKAKVTGPRL HSLHETS+V V+++TK++ + +
Sbjct: 2534 APGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYS 2593
Query: 2541 APGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKH 2600
+ +DASKVV +G GLS+A+VGQK+SFTVDCSKAG NM++VGVHGP+TPCEE+ VKH
Sbjct: 2594 SIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKH 2653
Query: 2601 VGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2639
+G+R+Y+V+Y +K+KG+Y L+VKWGDE +PGSP++V VP
Sbjct: 2654 MGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2692
Score = 905 bits (2340), Expect = 0.0
Identities = 727/2351 (30%), Positives = 1066/2351 (45%), Gaps = 254/2351 (10%)
Query: 280 NPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKN 339
NP RA G G++P G VK+ A+F V T+ AG GE+ V V+ P G +E KV D
Sbjct: 473 NPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDG- 531
Query: 340 RTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIAN 399
F Y P V G + VT+ + G I +SPFEV V G KV A GPGLE +G +
Sbjct: 532 -VFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPEAG-VQKVRAWGPGLE-TGQVG- 587
Query: 400 KTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVT 459
K+ F + G G + I+ P K + + +GD + Y PT G + VHV
Sbjct: 588 KSADFVVEAIGTEVGTLGFSIEGPSQAK----IECDDKGDGSCDVRYWPTEPGEYAVHVI 643
Query: 460 FAGVPIPRSPYTVTVGQA---CNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELK 516
I SP+ + A C P +A G GL+P G V + A+F + + AG G+LK
Sbjct: 644 CDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLK 703
Query: 517 VTVKGPKG-EERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECG 575
+ + G +K GDG + Y P P + + I+WGG N+ +SPF V VG
Sbjct: 704 LYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSH 763
Query: 576 NQKVRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVE------GPSQAKIECD--D 625
++V+ +GPG+E G + F V+ G + ++ GP++A I+ D
Sbjct: 764 PERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIK 823
Query: 626 KGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKT 685
+ + V+Y P AG Y + VL +++I SPF + D D +VKA GPGL +T
Sbjct: 824 NDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKV-DPSHD--ASKVKAEGPGLNRT 880
Query: 686 GVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPV--EALVKDNGNGTYSCSYVPRKPVKH 743
GV V KP FTV K GKA L VQ V + + DN + +Y+ Y +
Sbjct: 881 GVEVGKPTHFTVLTKGAGKAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNM 940
Query: 744 TAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAG-QG 802
V++GG +P SPF VNV +K+KV G + + + F+V+ AG QG
Sbjct: 941 AVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQG 997
Query: 803 DVSIGI----------KCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLF 852
+ + + K PG G AEA V+Y P G Y + + +
Sbjct: 998 QLDVRMTSPSRRPIPCKLEPG--GGAEAQ-------------AVRYMPPEEGPYKVDITY 1042
Query: 853 ADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFS 912
P SP V+ D SKV A GPGL G +G P F+++ K AG G L
Sbjct: 1043 DGHPVPGSPFAVEGVLPPDPSKVCAYGPGLK--GGLVGTPAPFSIDTKGAGTGGL----- 1095
Query: 913 GLT-KGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDL 971
GLT +G ++ D+ D + V Y P + G +N+ + IP SPF + P D
Sbjct: 1096 GLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDP 1155
Query: 972 SKIKVSGLG-EKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSV 1030
SK++ SG G E+ VG+ FTV AG + ++ +I+ S A V +V AD +
Sbjct: 1156 SKVRASGPGLERGKVGEAATFTVDCSEAG-EAELTIEIL--SDAGVKAEVLIHNNADGTY 1212
Query: 1031 -VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQ--GGSAGSPAR 1087
+ + P G Y + + Y G PVP P + S VK GPG++ G
Sbjct: 1213 HITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGVEPHGVLREVTTE 1272
Query: 1088 FTIDTKG-AGTGGLGLT--VEGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFAD 1142
FT+D + TGG +T V P A+ + DNGDGT V Y E G + + +L+ +
Sbjct: 1273 FTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDE 1332
Query: 1143 THIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAG 1202
+P SPF+ V D ++V+ GPGLE + +F V+ AG+ L + I E
Sbjct: 1333 VAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAI--EGP 1390
Query: 1203 LPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYG 1262
A++ +D+ DG+ T+ YIP PG Y V I +GG+P+P P ++ V+ VD V+C G
Sbjct: 1391 SEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSG 1450
Query: 1263 PGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYT 1322
PG+ G GV F+VD +Q G ++ V P+G V+D GDG + V YT
Sbjct: 1451 PGL-GAGVRARVPQTFTVDC---SQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYT 1506
Query: 1323 PYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSG--TTNKPNKFTVET 1380
P +G ++V V Y VP SPF++ V D S+VR GPG+ + + P +FT++
Sbjct: 1507 PATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDA 1566
Query: 1381 RGAGTGGLGLAVEGPS--EAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPF 1438
R AG G L + + P K + DN DG+ +V Y+P +G Y++ + YGG ++P SPF
Sbjct: 1567 RDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPF 1626
Query: 1439 KVPVHDVTDASK----VKCSGPGLSPGM---VRANLPQSFQVDTSKAGVAPLQVKVQGPK 1491
++ DASK V G GL + ++ VD AG + V P
Sbjct: 1627 RIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPD 1686
Query: 1492 GLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKAS 1551
G VDVV+N DGT + Y G Y I++ +G E +P SPF V L T + V
Sbjct: 1687 GAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHV--LATEEP--VVPV 1742
Query: 1552 GPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPD 1611
P + + P +L + F + +G L ++ P GK + +I DN DGT TV Y P
Sbjct: 1743 EP-MESMLRPFNLVIPFAVQ-----KGELTGEVRMPSGKTARPNITDNKDGTITVRYAPT 1796
Query: 1612 VTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAA 1671
G + + IKY G+ IP SP + V ++ + G G+ + + + T+ TK A
Sbjct: 1797 EKGLHQMGIKYDGNHIPGSPLQFY-VDAINSRHVSAYGPGLSHGM-VNKPATFTIVTKDA 1854
Query: 1672 GKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVT 1731
G+G ++ V P S+ ++ +N+DGT + Y PG Y I VRF +H+P SPF
Sbjct: 1855 GEGGLSLAVEGP--SKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPF-TA 1911
Query: 1732 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1791
+ GD +R+ QL VG + + DL
Sbjct: 1912 KITGDD-----SMRTSQLN-------------------VGTSTDVSLKITESDL------ 1941
Query: 1792 KKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFY 1851
++T +R PSG + + + + + P E G H + +R H+ SP +
Sbjct: 1942 --SQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKIL 1999
Query: 1852 V---DYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQ 1908
V + + V +G GL+ G + A F V+T++AG GGL L+IEGPSK +I+C D +
Sbjct: 2000 VGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDME 2059
Query: 1909 DGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINIS 1968
DGTC V+Y P PG Y I +K+ ++HVPGSPFT +VTG+ M+ S + A I S
Sbjct: 2060 DGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGS 2119
Query: 1969 ETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIP 2028
DL+L +P G F E L H +
Sbjct: 2120 TCDLNL----KIP------------------GNWFQMVSAQERLTRTFTRSSHTYTRTER 2157
Query: 2029 VVISQSEIGDASR-VRVSGQGLHEGHTFEP--AEFIIDTRDAGYGGLSLSIEGPSKVDIN 2085
IS++ G+ R VRV G F +F+ R +G ++ EG +
Sbjct: 2158 TEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGSITRQQEGEASSQDM 2217
Query: 2086 TEDL---------------EDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV--TG 2128
T + ED V + P E G + + +K+ QHVPGSPF V G
Sbjct: 2218 TAQVTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLG 2277
Query: 2129 EG---RVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIV-E 2184
EG +V+ T R + G + S+ E ++ V PS +AEI E
Sbjct: 2278 EGGAHKVRAGGTGLERGVA----GVPAEFSIWTREAGAGGLSIAVEGPS----KAEIAFE 2329
Query: 2185 GENHTYC-IRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERA 2243
C + +V E G + VS+K+ +H+P SPF V L + A ++
Sbjct: 2330 DRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSD-DARRLTVTSLQETGL 2388
Query: 2244 EAGVPAEFSIWTREAGAGGLAIAVEGPSKA--EISFEDRKDGSCGVAYVVQEPGDYEVSV 2301
+ PA F++ A G + V PS A E + + ++ E G + + V
Sbjct: 2389 KVNQPASFAVQLNGA-RGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDV 2447
Query: 2302 KFNEEHIPDSPFVVPVA--SPSGDARRLTVSSLQESGLKVNQPASFAV-SLNGAKGAIDA 2358
KFN HIP SPF + V S +GD ++ G + F V +LN GA+
Sbjct: 2448 KFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSV 2507
Query: 2359 KVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG-THIPGSPFKIRVGEP-- 2415
+ PS +C + + V + P G YLI +K+ G HI GSPFK +V P
Sbjct: 2508 TIDGPSKVQLDCREC---PEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRL 2564
Query: 2416 --GH------------------------------GGDPGLVSAYGAGLEGGVTGNPAEFV 2443
GH D V G GL G F
Sbjct: 2565 SGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFT 2624
Query: 2444 VNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPMAPGSYLISIKYGGPY 2497
V+ S AG + V + GP K C+E Y VTYT G Y++ +K+G
Sbjct: 2625 VDCSKAGTNMMMVGVHGP---KTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDE- 2680
Query: 2498 HIGGSPFKAKV 2508
+ GSPFK KV
Sbjct: 2681 SVPGSPFKVKV 2691
>gi|239755812 PREDICTED: similar to spectrin, beta, non-erythrocytic
2 [Homo sapiens]
Length = 158
Score = 191 bits (485), Expect = 8e-48
Identities = 93/120 (77%), Positives = 108/120 (90%)
Query: 89 MHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHY 148
M+ K++QRPTFRQMQL+NVSVALEFLDR+SIKLVSIDSKA VDGNLKLILGL+WTLIL Y
Sbjct: 1 MYLKYHQRPTFRQMQLKNVSVALEFLDRDSIKLVSIDSKATVDGNLKLILGLVWTLILRY 60
Query: 149 SISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPG 208
SIS P+ ++E D++AKKQ KQRLLGWIQNK+P LPITNFS++WQ +AL ALVDSCAPG
Sbjct: 61 SISTPVCEDEGDDDAKKQMRKQRLLGWIQNKVPYLPITNFSQNWQDSKALRALVDSCAPG 120
>gi|12025678 actinin, alpha 4 [Homo sapiens]
Length = 911
Score = 166 bits (419), Expect = 4e-40
Identities = 97/262 (37%), Positives = 150/262 (57%), Gaps = 17/262 (6%)
Query: 9 GQSAAGAAPGGGVDTRD--AEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIAN 66
G S+AG GGG D A+ ++DL D W+K Q+ TFT WCN HL+ +I N
Sbjct: 14 GPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIEN 73
Query: 67 LQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDS 126
+ D DGL+L+ LLEV+S +++ + +R R ++ NV+ AL+F+ + +KLVSI +
Sbjct: 74 IDEDFRDGLKLMLLLEVISGERLPKP--ERGKMRVHKINNVNKALDFIASKGVKLVSIGA 131
Query: 127 KAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNK---LPQL 183
+ IVDGN K+ LG+IWT+IL ++I +D ++ + K+ LL W Q K +
Sbjct: 132 EEIVDGNAKMTLGMIWTIILRFAI--------QDISVEETSAKEGLLLWCQRKTAPYKNV 183
Query: 184 PITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVIT 243
+ NF W+ G A AL+ P L ++D PVTN A + A+ +L IP+++
Sbjct: 184 NVQNFHISWKDGLAFNALIHRHRPELI-EYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLD 242
Query: 244 PEEIVD-PNVDEHSVMTYLSQF 264
E+IV+ DE ++MTY+S F
Sbjct: 243 AEDIVNTARPDEKAIMTYVSSF 264
>gi|4557241 actinin, alpha 3 [Homo sapiens]
Length = 901
Score = 159 bits (401), Expect = 5e-38
Identities = 94/261 (36%), Positives = 147/261 (56%), Gaps = 17/261 (6%)
Query: 8 AGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANL 67
AG+ GGG E ++DL D W+K Q+ TFT WCN HL+ +I N+
Sbjct: 12 AGEGRFAGGGGGGEYMEQEE--DWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENI 69
Query: 68 QTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSK 127
+ D +GL+L+ LLEV+S +++ R + F ++ NV+ AL+F+ + +KLVSI ++
Sbjct: 70 EEDFRNGLKLMLLLEVISGERLPRPDKGKMRFH--KIANVNKALDFIASKGVKLVSIGAE 127
Query: 128 AIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLP---QLP 184
IVDGNLK+ LG+IWT+IL ++I +D ++ + K+ LL W Q K +
Sbjct: 128 EIVDGNLKMTLGMIWTIILRFAI--------QDISVEETSAKEGLLLWCQRKTAPYRNVN 179
Query: 185 ITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITP 244
+ NF W+ G AL AL+ P L D+ P+ N A + A+ +L IP+++
Sbjct: 180 VQNFHTSWKDGLALCALIHRHRPDLI-DYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDA 238
Query: 245 EEIVD-PNVDEHSVMTYLSQF 264
E+IV+ P DE ++MTY+S F
Sbjct: 239 EDIVNTPKPDEKAIMTYVSCF 259
>gi|4501893 actinin, alpha 2 [Homo sapiens]
Length = 894
Score = 153 bits (387), Expect = 2e-36
Identities = 87/237 (36%), Positives = 140/237 (59%), Gaps = 15/237 (6%)
Query: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHR 91
++DL D W+K Q+ TFT WCN HL+ +I N++ D +GL+L+ LLEV+S +++ +
Sbjct: 27 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPK 86
Query: 92 KHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 151
R R ++ NV+ AL+++ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 87 P--DRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 143
Query: 152 MPMWDEEEDEEAKKQTPKQRLLGWIQNKLP---QLPITNFSRDWQSGRALGALVDSCAPG 208
+D ++ + K+ LL W Q K + I NF W+ G L AL+ P
Sbjct: 144 -------QDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPD 196
Query: 209 LCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVD-PNVDEHSVMTYLSQF 264
L D+ + P+ N AM+ A+ L IP+++ E+IV+ P DE ++MTY+S F
Sbjct: 197 LI-DYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCF 252
>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
Length = 887
Score = 152 bits (385), Expect = 3e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHR 91
++DL D W+K Q+ TFT WCN HL+ +I N++ D DGL+L+ LLEV+S +++ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 92 KHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 151
+R R ++ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 152 MPMWDEEEDEEAKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPG 208
+D ++ + K+ LL W Q K + I NF W+ G AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 209 LCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIV-DPNVDEHSVMTYLSQF 264
L D+ P+TN A A+ +L IP+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
Length = 914
Score = 152 bits (385), Expect = 3e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHR 91
++DL D W+K Q+ TFT WCN HL+ +I N++ D DGL+L+ LLEV+S +++ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 92 KHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 151
+R R ++ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 152 MPMWDEEEDEEAKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPG 208
+D ++ + K+ LL W Q K + I NF W+ G AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 209 LCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIV-DPNVDEHSVMTYLSQF 264
L D+ P+TN A A+ +L IP+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
Length = 892
Score = 152 bits (385), Expect = 3e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHR 91
++DL D W+K Q+ TFT WCN HL+ +I N++ D DGL+L+ LLEV+S +++ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 92 KHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 151
+R R ++ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 152 MPMWDEEEDEEAKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPG 208
+D ++ + K+ LL W Q K + I NF W+ G AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 209 LCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIV-DPNVDEHSVMTYLSQF 264
L D+ P+TN A A+ +L IP+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 144 bits (363), Expect = 1e-33
Identities = 93/235 (39%), Positives = 136/235 (57%), Gaps = 16/235 (6%)
Query: 33 KDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRK 92
K LA++ + +Q+ TFT+W N HL VS RI +L TDL DG LI LLEVLS +++
Sbjct: 46 KALADER--EAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL--- 100
Query: 93 HNQRPTFRQMQ---LENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYS 149
+PT +M+ LENV AL+FL + + L ++ S IVDGN +L LGLIWT+IL +
Sbjct: 101 --PKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQ 158
Query: 150 ISMPMWDEEEDEEAKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCA 206
I + E+++E K++ K LL W Q K P + I NF+ W+ G A AL+
Sbjct: 159 IQDISVETEDNKE--KKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHR 216
Query: 207 PGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYL 261
P L D+D S N + A A+ LG+ +++ PE+I + DE S++TY+
Sbjct: 217 PDLI-DFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYV 270
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 144 bits (362), Expect = 1e-33
Identities = 90/224 (40%), Positives = 130/224 (58%), Gaps = 14/224 (6%)
Query: 44 IQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQ 103
+Q+ TFT+W N HL VS RI +L TDL DG LI LLEVLS +++ +PT +M+
Sbjct: 42 VQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL-----PKPTKGRMR 96
Query: 104 ---LENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEED 160
LENV AL+FL + + L ++ S IVDGN +L LGLIWT+IL + I + E++
Sbjct: 97 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDN 156
Query: 161 EEAKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWD 217
+E K++ K LL W Q K P + I NF+ W+ G A AL+ P L D+D
Sbjct: 157 KE--KKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLI-DFDKLK 213
Query: 218 ASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYL 261
S N + A A+ LG+ +++ PE+I + DE S++TY+
Sbjct: 214 KSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYV 257
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 143 bits (360), Expect = 3e-33
Identities = 88/258 (34%), Positives = 142/258 (55%), Gaps = 12/258 (4%)
Query: 9 GQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWK-KIQQNTFTRWCNEHLKCVSKRIANL 67
G++ GGG + + + E+ + A + ++Q+ TFT+W N+HL + I++L
Sbjct: 34 GKTQRSRRSGGGAGSNGSVLDPAERAVIRIADERDRVQKKTFTKWVNKHLIKAQRHISDL 93
Query: 68 QTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSK 127
DL DG LI+LLEVLS + R+ + R +L+NV +AL++L +KLV+I +
Sbjct: 94 YEDLRDGHNLISLLEVLSGDSLPREKGR---MRFHKLQNVQIALDYLRHRQVKLVNIRND 150
Query: 128 AIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL---PQLP 184
I DGN KL LGLIWT+ILH+ IS D + +++ T K++LL W Q + L
Sbjct: 151 DIADGNPKLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLR 206
Query: 185 ITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITP 244
NF+ W+ GR A++ P L D + + N +A A+ LG+ +++ P
Sbjct: 207 CDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDP 265
Query: 245 EEIVDPNVDEHSVMTYLS 262
E++ P DE S++TY+S
Sbjct: 266 EDVDVPQPDEKSIITYVS 283
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 142 bits (359), Expect = 3e-33
Identities = 90/227 (39%), Positives = 126/227 (55%), Gaps = 14/227 (6%)
Query: 44 IQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQ 103
+Q+ TFT+W N HL VS RI +L DL DG LI LLEVLS + + +PT +M+
Sbjct: 55 VQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEML-----PKPTKGKMR 109
Query: 104 ---LENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEED 160
LENV AL+FL + + L ++ S IVDGN +L+LGLIWT+IL + I + +E
Sbjct: 110 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEG 169
Query: 161 EEAKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWD 217
E + + K LL W Q K P + +TNF+ W+ G A AL+ P L D+D
Sbjct: 170 RETR--SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLI-DFDKLK 226
Query: 218 ASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQF 264
S N A A+ LGI ++ PE++ N DE S++TY+ F
Sbjct: 227 DSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAF 273
>gi|67782319 spectrin beta isoform b [Homo sapiens]
Length = 2137
Score = 142 bits (359), Expect = 3e-33
Identities = 90/227 (39%), Positives = 126/227 (55%), Gaps = 14/227 (6%)
Query: 44 IQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQ 103
+Q+ TFT+W N HL VS RI +L DL DG LI LLEVLS + + +PT +M+
Sbjct: 55 VQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEML-----PKPTKGKMR 109
Query: 104 ---LENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEED 160
LENV AL+FL + + L ++ S IVDGN +L+LGLIWT+IL + I + +E
Sbjct: 110 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEG 169
Query: 161 EEAKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWD 217
E + + K LL W Q K P + +TNF+ W+ G A AL+ P L D+D
Sbjct: 170 RETR--SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLI-DFDKLK 226
Query: 218 ASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQF 264
S N A A+ LGI ++ PE++ N DE S++TY+ F
Sbjct: 227 DSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAF 273
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 139 bits (350), Expect = 4e-32
Identities = 90/231 (38%), Positives = 130/231 (56%), Gaps = 16/231 (6%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
++Q+ TFT+W N+HL V K I +L DL DG LI+LLEVLS K+ R+ + R
Sbjct: 78 RVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGR---MRFH 134
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL+FL + +KLV+I + I DGN KL LGLIWT+ILH+ IS D E
Sbjct: 135 RLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS----DIYISGE 190
Query: 163 AKKQTPKQRLLGWIQN---KLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
+ + K++LL W Q + TNFS W G+ AL+ P L D +
Sbjct: 191 SGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLV-DMERVQIQ 249
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQ----FPK 266
N +A + A+ LG+ +++ E++ P+ DE SV+TY+S FPK
Sbjct: 250 SNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPK 299
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 139 bits (349), Expect = 5e-32
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
++Q+ TFT+W N+HL + I++L DL DG LI+LLEVLS + R+ + R
Sbjct: 42 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR---MRFH 98
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS D + +
Sbjct: 99 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 154
Query: 163 AKKQTPKQRLLGWIQNKL---PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
++ T K++LL W Q + L NF+ W+ GR A++ P L D +
Sbjct: 155 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 213
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLS 262
+ N +A A+ LG+ +++ PE++ P DE S++TY+S
Sbjct: 214 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 256
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 139 bits (349), Expect = 5e-32
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
++Q+ TFT+W N+HL + I++L DL DG LI+LLEVLS + R+ + R
Sbjct: 46 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR---MRFH 102
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS D + +
Sbjct: 103 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 158
Query: 163 AKKQTPKQRLLGWIQNKL---PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
++ T K++LL W Q + L NF+ W+ GR A++ P L D +
Sbjct: 159 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 217
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLS 262
+ N +A A+ LG+ +++ PE++ P DE S++TY+S
Sbjct: 218 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 260
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 139 bits (349), Expect = 5e-32
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
++Q+ TFT+W N+HL + I++L DL DG LI+LLEVLS + R+ + R
Sbjct: 42 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR---MRFH 98
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS D + +
Sbjct: 99 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 154
Query: 163 AKKQTPKQRLLGWIQNKL---PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
++ T K++LL W Q + L NF+ W+ GR A++ P L D +
Sbjct: 155 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 213
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLS 262
+ N +A A+ LG+ +++ PE++ P DE S++TY+S
Sbjct: 214 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 256
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 139 bits (349), Expect = 5e-32
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
++Q+ TFT+W N+HL + I++L DL DG LI+LLEVLS + R+ + R
Sbjct: 10 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR---MRFH 66
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS D + +
Sbjct: 67 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 122
Query: 163 AKKQTPKQRLLGWIQNKL---PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
++ T K++LL W Q + L NF+ W+ GR A++ P L D +
Sbjct: 123 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 181
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLS 262
+ N +A A+ LG+ +++ PE++ P DE S++TY+S
Sbjct: 182 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 224
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 139 bits (349), Expect = 5e-32
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
++Q+ TFT+W N+HL + I++L DL DG LI+LLEVLS + R+ + R
Sbjct: 179 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR---MRFH 235
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS D + +
Sbjct: 236 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 291
Query: 163 AKKQTPKQRLLGWIQNKL---PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
++ T K++LL W Q + L NF+ W+ GR A++ P L D +
Sbjct: 292 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 350
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLS 262
+ N +A A+ LG+ +++ PE++ P DE S++TY+S
Sbjct: 351 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 393
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 139 bits (349), Expect = 5e-32
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
++Q+ TFT+W N+HL + I++L DL DG LI+LLEVLS + R+ + R
Sbjct: 20 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR---MRFH 76
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS D + +
Sbjct: 77 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 132
Query: 163 AKKQTPKQRLLGWIQNKL---PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
++ T K++LL W Q + L NF+ W+ GR A++ P L D +
Sbjct: 133 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 191
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLS 262
+ N +A A+ LG+ +++ PE++ P DE S++TY+S
Sbjct: 192 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 234
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 139 bits (349), Expect = 5e-32
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
++Q+ TFT+W N+HL + I++L DL DG LI+LLEVLS + R+ + R
Sbjct: 28 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR---MRFH 84
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS D + +
Sbjct: 85 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 140
Query: 163 AKKQTPKQRLLGWIQNKL---PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
++ T K++LL W Q + L NF+ W+ GR A++ P L D +
Sbjct: 141 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 199
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLS 262
+ N +A A+ LG+ +++ PE++ P DE S++TY+S
Sbjct: 200 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 242
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 138 bits (347), Expect = 8e-32
Identities = 98/281 (34%), Positives = 147/281 (52%), Gaps = 34/281 (12%)
Query: 10 QSAAGAAPGGGVDTRDAEMPATEK-----------DLAEDAPWK------KIQQNTFTRW 52
Q + A+P G DT +P E+ D AE A + K+Q+ TFT+W
Sbjct: 15 QKSGSASPAPG-DTLPWNLPKHERSKRKIQGGSVLDPAERAVLRIADERDKVQKKTFTKW 73
Query: 53 CNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALE 112
N+HL V K + +L DL DG LI+LLEVLS + R+ + R +L+NV +AL+
Sbjct: 74 INQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGR---MRFHRLQNVQIALD 130
Query: 113 FLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRL 172
+L R +KLV+I + I DGN KL LGLIWT+ILH+ IS D E++ + K+RL
Sbjct: 131 YLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS----DIHVTGESEDMSAKERL 186
Query: 173 LGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAM 229
L W Q + NF+ W+ G+ A++ P L D ++ + N A
Sbjct: 187 LLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQSNLANLEHAF 245
Query: 230 QQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQ----FPK 266
A+ +G+ +++ PE++ + DE SV+TY+S FPK
Sbjct: 246 YVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 285
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 138 bits (347), Expect = 8e-32
Identities = 98/281 (34%), Positives = 147/281 (52%), Gaps = 34/281 (12%)
Query: 10 QSAAGAAPGGGVDTRDAEMPATEK-----------DLAEDAPWK------KIQQNTFTRW 52
Q + A+P G DT +P E+ D AE A + K+Q+ TFT+W
Sbjct: 26 QKSGSASPAPG-DTLPWNLPKHERSKRKIQGGSVLDPAERAVLRIADERDKVQKKTFTKW 84
Query: 53 CNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALE 112
N+HL V K + +L DL DG LI+LLEVLS + R+ + R +L+NV +AL+
Sbjct: 85 INQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGR---MRFHRLQNVQIALD 141
Query: 113 FLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRL 172
+L R +KLV+I + I DGN KL LGLIWT+ILH+ IS D E++ + K+RL
Sbjct: 142 YLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS----DIHVTGESEDMSAKERL 197
Query: 173 LGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAM 229
L W Q + NF+ W+ G+ A++ P L D ++ + N A
Sbjct: 198 LLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQSNLANLEHAF 256
Query: 230 QQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQ----FPK 266
A+ +G+ +++ PE++ + DE SV+TY+S FPK
Sbjct: 257 YVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 296
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 138 bits (347), Expect = 8e-32
Identities = 98/281 (34%), Positives = 147/281 (52%), Gaps = 34/281 (12%)
Query: 10 QSAAGAAPGGGVDTRDAEMPATEK-----------DLAEDAPWK------KIQQNTFTRW 52
Q + A+P G DT +P E+ D AE A + K+Q+ TFT+W
Sbjct: 164 QKSGSASPAPG-DTLPWNLPKHERSKRKIQGGSVLDPAERAVLRIADERDKVQKKTFTKW 222
Query: 53 CNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALE 112
N+HL V K + +L DL DG LI+LLEVLS + R+ + R +L+NV +AL+
Sbjct: 223 INQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGR---MRFHRLQNVQIALD 279
Query: 113 FLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRL 172
+L R +KLV+I + I DGN KL LGLIWT+ILH+ IS D E++ + K+RL
Sbjct: 280 YLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS----DIHVTGESEDMSAKERL 335
Query: 173 LGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAM 229
L W Q + NF+ W+ G+ A++ P L D ++ + N A
Sbjct: 336 LLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQSNLANLEHAF 394
Query: 230 QQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQ----FPK 266
A+ +G+ +++ PE++ + DE SV+TY+S FPK
Sbjct: 395 YVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 434
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 137 bits (346), Expect = 1e-31
Identities = 86/231 (37%), Positives = 130/231 (56%), Gaps = 16/231 (6%)
Query: 43 KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQM 102
K+Q+ TFT+W N+HL V K + +L DL DG LI+LLEVLS + R+ + R
Sbjct: 35 KVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGR---MRFH 91
Query: 103 QLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEE 162
+L+NV +AL++L R +KLV+I + I DGN KL LGLIWT+ILH+ IS D E
Sbjct: 92 RLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS----DIHVTGE 147
Query: 163 AKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDAS 219
++ + K+RLL W Q + NF+ W+ G+ A++ P L D ++
Sbjct: 148 SEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQ 206
Query: 220 KPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQ----FPK 266
+ N A A+ +G+ +++ PE++ + DE SV+TY+S FPK
Sbjct: 207 SNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 256
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
[Homo sapiens]
Length = 2564
Score = 137 bits (344), Expect = 2e-31
Identities = 86/235 (36%), Positives = 129/235 (54%), Gaps = 10/235 (4%)
Query: 33 KDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRK 92
K LA++ + +Q+ TFT+W N HL V I +L DL DG L LLEVLS +++ R
Sbjct: 53 KALADER--EAVQKKTFTKWVNSHLARVGCHIGDLYVDLRDGFVLTRLLEVLSGEQLPRP 110
Query: 93 HNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISM 152
R R LENV AL+FL + + L ++ S IVDGN +L LGL+WT+IL + I +
Sbjct: 111 TRGR--MRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQV 168
Query: 153 PMWDEEEDEEAKKQTPKQRLLGWIQNK---LPQLPITNFSRDWQSGRALGALVDSCAPGL 209
+ E++ E + + K LL W Q K P++ I NF+ W+ G A AL+ P L
Sbjct: 169 IKIETEDNRETR--SAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDL 226
Query: 210 CPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQF 264
D+ S N + A + A+ LG+ +++ PE++ DE S++TY+ F
Sbjct: 227 V-DFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSF 280
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 118,221,939
Number of Sequences: 37866
Number of extensions: 6476026
Number of successful extensions: 17602
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 13356
Number of HSP's gapped (non-prelim): 646
length of query: 2639
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2520
effective length of database: 13,741,464
effective search space: 34628489280
effective search space used: 34628489280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.