Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 23503303
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]
(436 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens] 879 0.0
gi|38569460 SNF1-like kinase 2 [Homo sapiens] 265 6e-71
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens] 261 7e-70
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor... 256 4e-68
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor... 256 4e-68
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform... 256 4e-68
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor... 255 5e-68
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor... 255 5e-68
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor... 255 5e-68
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor... 255 5e-68
gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform... 255 5e-68
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor... 255 5e-68
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s... 255 5e-68
gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo ... 255 6e-68
gi|116256471 SNF1-like kinase [Homo sapiens] 254 8e-68
gi|156105707 SNF related kinase [Homo sapiens] 220 2e-57
gi|156105705 SNF related kinase [Homo sapiens] 220 2e-57
gi|46877068 AMP-activated protein kinase alpha 2 catalytic subun... 213 3e-55
gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic sub... 213 4e-55
gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic sub... 202 4e-52
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 200 2e-51
gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens] 200 2e-51
gi|116089335 BR serine/threonine kinase 2 [Homo sapiens] 198 9e-51
gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens] 195 6e-50
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens] 192 4e-49
gi|7657214 hormonally upregulated Neu-associated kinase [Homo sa... 176 5e-44
gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca... 164 2e-40
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 164 2e-40
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 163 2e-40
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 160 2e-39
>gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]
Length = 436
Score = 879 bits (2272), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MTAVYMNGGGLVNPHYARWDRRDSVESGCQTESSKEGEEGQPRQLTPFEKLTQDMSQDEK 60
MTAVYMNGGGLVNPHYARWDRRDSVESGCQTESSKEGEEGQPRQLTPFEKLTQDMSQDEK
Sbjct: 1 MTAVYMNGGGLVNPHYARWDRRDSVESGCQTESSKEGEEGQPRQLTPFEKLTQDMSQDEK 60
Query: 61 VVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSR 120
VVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSR
Sbjct: 61 VVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSR 120
Query: 121 EISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQI 180
EISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQI
Sbjct: 121 EISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQI 180
Query: 181 VSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPE 240
VSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPE
Sbjct: 181 VSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPE 240
Query: 241 LFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHR 300
LFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHR
Sbjct: 241 LFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHR 300
Query: 301 LIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKST 360
LIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKST
Sbjct: 301 LIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKST 360
Query: 361 LEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKERDLKKGS 420
LEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKERDLKKGS
Sbjct: 361 LEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKERDLKKGS 420
Query: 421 RVYRGIRHTSKFCSIL 436
RVYRGIRHTSKFCSIL
Sbjct: 421 RVYRGIRHTSKFCSIL 436
>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
Length = 926
Score = 265 bits (677), Expect = 6e-71
Identities = 140/346 (40%), Positives = 213/346 (61%), Gaps = 7/346 (2%)
Query: 70 RIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLH 129
R+GFY I G +G GNF+ VKLG H +TK +VAIKI+DK++LD + RE+ M+ L
Sbjct: 16 RVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLD 75
Query: 130 HPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHE 189
HP+II+LY+V+ET S L+LV EYA GE+F ++ G+L+E E++ F QI+SAV + H
Sbjct: 76 HPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHG 135
Query: 190 NQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIG 249
+I+HRDLKAEN+ +N +K+ DFGF K GE+L T+CGSPPYAAPE+F + Y G
Sbjct: 136 RKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEG 195
Query: 250 IYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQI 309
+DIW++GV+LY +V G +PF T+ L++ +LEG + +P +SE C LIR +L
Sbjct: 196 PQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLD 255
Query: 310 PTERYGIDCIMNDEWMQ-GVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITE 368
P++R I I +WM VP P+ L P+ ++ E +V + LGI +
Sbjct: 256 PSKRLTIAQIKEHKWMLIEVPVQRPV----LYPQEQENEPSIGEFNEQVLRLMHSLGIDQ 311
Query: 369 EHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKER 414
+ + + + +Y +++ R++ ++ S PV D ++R
Sbjct: 312 QKTIESLQNKSYNHFAAIYFLLVERLKSHRS--SFPVEQRLDGRQR 355
>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
Length = 1263
Score = 261 bits (668), Expect = 7e-70
Identities = 135/340 (39%), Positives = 202/340 (59%)
Query: 70 RIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLH 129
RIG+Y I IG GNF+ VK H +TK KVAIKI+DKT+LD++ + + RE+ M+ L
Sbjct: 4 RIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLC 63
Query: 130 HPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHE 189
HP+IIRLY+V+ET ++LV EYA GGE+F + G+++E E++ F QIV+AV H
Sbjct: 64 HPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHC 123
Query: 190 NQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIG 249
I+HRDLKAEN+ +N +K+ DFGFS + G++L T+CGSPPYAAPELF + Y G
Sbjct: 124 RNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDG 183
Query: 250 IYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQI 309
VDIW+LGV+LY +V G +PF T+ L+ +L G + +P +S C LIR +L
Sbjct: 184 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLD 243
Query: 310 PTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEE 369
P +R ++ I +WM+ + + + L E + +V +E +G+ +E
Sbjct: 244 PNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKE 303
Query: 370 HIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLP 409
+ DA + +Y ++ R +R K L + +P
Sbjct: 304 QTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRLGALPSMP 343
>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
[Homo sapiens]
Length = 744
Score = 256 bits (653), Expect = 4e-68
Identities = 131/332 (39%), Positives = 205/332 (61%), Gaps = 8/332 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT +VAIKI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNH 112
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+L+MEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
+I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
Query: 311 TERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEH 370
+R ++ IM D W+ L+PF +S+ + + +G ++E
Sbjct: 293 IKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRI--------DIMVGMGYSQEE 344
Query: 371 IRNNQGRDARSSITGVYRIILHRVQRKKALES 402
I+ + + IT Y ++ + A +S
Sbjct: 345 IQESLSKMKYDEITATYLLLGRKSSELDASDS 376
>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
[Homo sapiens]
Length = 753
Score = 256 bits (653), Expect = 4e-68
Identities = 131/332 (39%), Positives = 205/332 (61%), Gaps = 8/332 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT +VAIKI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNH 112
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+L+MEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
+I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
Query: 311 TERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEH 370
+R ++ IM D W+ L+PF +S+ + + +G ++E
Sbjct: 293 IKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRI--------DIMVGMGYSQEE 344
Query: 371 IRNNQGRDARSSITGVYRIILHRVQRKKALES 402
I+ + + IT Y ++ + A +S
Sbjct: 345 IQESLSKMKYDEITATYLLLGRKSSELDASDS 376
>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
[Homo sapiens]
Length = 729
Score = 256 bits (653), Expect = 4e-68
Identities = 131/332 (39%), Positives = 205/332 (61%), Gaps = 8/332 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT +VAIKI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNH 112
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+L+MEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
+I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
Query: 311 TERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEH 370
+R ++ IM D W+ L+PF +S+ + + +G ++E
Sbjct: 293 IKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRI--------DIMVGMGYSQEE 344
Query: 371 IRNNQGRDARSSITGVYRIILHRVQRKKALES 402
I+ + + IT Y ++ + A +S
Sbjct: 345 IQESLSKMKYDEITATYLLLGRKSSELDASDS 376
>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
[Homo sapiens]
Length = 709
Score = 255 bits (652), Expect = 5e-68
Identities = 128/298 (42%), Positives = 196/298 (65%), Gaps = 8/298 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT ++VA+KI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNH 109
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+LVMEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 169
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 170 FIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGP 229
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 230 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNP 289
Query: 311 TERYGIDCIMNDEWM-------QGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTL 361
++R ++ IM D WM + PY PL ++ DP+ ++ E++ +L
Sbjct: 290 SKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYK-DPRRTELMVSMGYTREEIQDSL 346
>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
[Homo sapiens]
Length = 719
Score = 255 bits (652), Expect = 5e-68
Identities = 128/298 (42%), Positives = 196/298 (65%), Gaps = 8/298 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT ++VA+KI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNH 109
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+LVMEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 169
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 170 FIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGP 229
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 230 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNP 289
Query: 311 TERYGIDCIMNDEWM-------QGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTL 361
++R ++ IM D WM + PY PL ++ DP+ ++ E++ +L
Sbjct: 290 SKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYK-DPRRTELMVSMGYTREEIQDSL 346
>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
[Homo sapiens]
Length = 788
Score = 255 bits (652), Expect = 5e-68
Identities = 128/298 (42%), Positives = 196/298 (65%), Gaps = 8/298 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT ++VA+KI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNH 109
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+LVMEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 169
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 170 FIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGP 229
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 230 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNP 289
Query: 311 TERYGIDCIMNDEWM-------QGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTL 361
++R ++ IM D WM + PY PL ++ DP+ ++ E++ +L
Sbjct: 290 SKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYK-DPRRTELMVSMGYTREEIQDSL 346
>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
[Homo sapiens]
Length = 724
Score = 255 bits (652), Expect = 5e-68
Identities = 128/298 (42%), Positives = 196/298 (65%), Gaps = 8/298 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT ++VA+KI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNH 109
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+LVMEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 169
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 170 FIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGP 229
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 230 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNP 289
Query: 311 TERYGIDCIMNDEWM-------QGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTL 361
++R ++ IM D WM + PY PL ++ DP+ ++ E++ +L
Sbjct: 290 SKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYK-DPRRTELMVSMGYTREEIQDSL 346
>gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform a
[Homo sapiens]
Length = 745
Score = 255 bits (652), Expect = 5e-68
Identities = 128/298 (42%), Positives = 196/298 (65%), Gaps = 8/298 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT ++VA+KI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNH 76
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+LVMEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 77 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 136
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 137 FIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGP 196
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 197 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNP 256
Query: 311 TERYGIDCIMNDEWM-------QGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTL 361
++R ++ IM D WM + PY PL ++ DP+ ++ E++ +L
Sbjct: 257 SKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYK-DPRRTELMVSMGYTREEIQDSL 313
>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
[Homo sapiens]
Length = 713
Score = 255 bits (652), Expect = 5e-68
Identities = 129/320 (40%), Positives = 201/320 (62%), Gaps = 8/320 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR+ IG GNF++VKL H LT +VAIKI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNH 112
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+L+MEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
+I+HRDLKAEN+ ++ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ L P
Sbjct: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
Query: 311 TERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEH 370
+R ++ IM D W+ L+PF +S+ + + +G ++E
Sbjct: 293 IKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRI--------DIMVGMGYSQEE 344
Query: 371 IRNNQGRDARSSITGVYRII 390
I+ + + IT Y ++
Sbjct: 345 IQESLSKMKYDEITATYLLL 364
>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
sapiens]
Length = 688
Score = 255 bits (652), Expect = 5e-68
Identities = 137/360 (38%), Positives = 212/360 (58%), Gaps = 10/360 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
+G YR+ IG GNF++VKL H LT +VAIKI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 56 VGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNH 115
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+LVMEYA GE+F + + G++ E E++ F QIVSAV + H+
Sbjct: 116 PNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQK 175
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I+HRDLKAEN+ + +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 176 NIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGP 235
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VDIW+LGV+LY +V+G++PF + +L++ +L G Y VP ++S C ++R L P
Sbjct: 236 EVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNP 295
Query: 311 TERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEH 370
+R ++ IM D+W+ L+P+ + +T ++ + +G T E
Sbjct: 296 AKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIE--------VMVGMGYTREE 347
Query: 371 IRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPK-ERDLKKGSRVYRGIRHT 429
I+ + + +T Y ++L R + P + L + D G+ +G H+
Sbjct: 348 IKESLTSQKYNEVTATY-LLLGRKTEEGGDRGAPGLALARVRAPSDTTNGTSSSKGTSHS 406
>gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo
sapiens]
Length = 795
Score = 255 bits (651), Expect = 6e-68
Identities = 129/298 (43%), Positives = 193/298 (64%), Gaps = 8/298 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
IG YR++ IG GNF++VKL H LT +VA+KI+DKT+L+ + + L RE+ M+ L+H
Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNH 116
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
PNI++L+EV+ET L+LVMEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I+HRDLKAEN+ + +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 177 YIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGP 236
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
VD+W+LGV+LY +V+G++PF + + +L++ +L G Y +P ++S C L++ +L P
Sbjct: 237 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNP 296
Query: 311 TERYGIDCIMNDEWM-------QGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTL 361
+R ++ IM D WM + PY P +P D K + T+ +E+ L
Sbjct: 297 IKRGSLEQIMKDRWMNVGHEEEELKPYTEP-DPDFNDTKRIDIMVTMGFARDEINDAL 353
>gi|116256471 SNF1-like kinase [Homo sapiens]
Length = 783
Score = 254 bits (650), Expect = 8e-68
Identities = 137/352 (38%), Positives = 208/352 (59%), Gaps = 10/352 (2%)
Query: 70 RIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLH 129
R+GFY I +G GNF+ VKL H +TK +VAIKI+DKT+LD + RE+ M+ L+
Sbjct: 23 RVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLN 82
Query: 130 HPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHE 189
HP+II+LY+V+ET L++V E+A GE+F +++ G LSE E++ F QI+SAV++ H+
Sbjct: 83 HPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHD 142
Query: 190 NQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIG 249
+ I+HRDLK EN+ N +K+ DFGF K GE L+T+CGSPPYAAPE+F + Y G
Sbjct: 143 HHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEG 202
Query: 250 IYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQI 309
+DIW+LGV+LY +V G++PF + L++ +LEG + +P +S+ C LIR +L
Sbjct: 203 PQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVD 262
Query: 310 PTERYGIDCIMNDEWMQGVP-YPTPLEP-FQLDPKHLSETSTLKEEENEVKSTLEHLGIT 367
P R I I WM+ P P P P F S TS L + + + ++ LG+
Sbjct: 263 PARRITIAQIRQHRWMRAEPCLPGPACPAFSAH----SYTSNLGDYDEQALGIMQTLGVD 318
Query: 368 EEHIRNNQGRDARSSITGVYRIILHRVQRKKALESV---PVMMLPDPKERDL 416
+ + + + +Y ++L R++ + + P P P+ DL
Sbjct: 319 RQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQCARPGPARQ-PRPRSSDL 369
>gi|156105707 SNF related kinase [Homo sapiens]
Length = 765
Score = 220 bits (561), Expect = 2e-57
Identities = 130/337 (38%), Positives = 195/337 (57%), Gaps = 12/337 (3%)
Query: 68 GKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEK 127
GK G Y + +G G+F+ VKL H T EKVA+K++DKTKLD L +E+ M+
Sbjct: 10 GKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKL 69
Query: 128 LHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKIST-EGKLSEPESKLIFSQIVSAVKH 186
+ HPNI+RLYEV++T +KL+L++E GG++F I E L+E +K F+QIV A+ +
Sbjct: 70 VQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISY 129
Query: 187 MHENQIIHRDLKAENV-FYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDE 245
H+ ++HRDLK ENV F+ VK+ DFGFS + G+ L T CGS Y+APE+ +
Sbjct: 130 CHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGD 189
Query: 246 HYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGV 305
Y VDIW+LGV+L+ +V G PF+ ++ I++ Y+VP HVS+ C LI +
Sbjct: 190 EYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRM 249
Query: 306 LQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQL---DPKHLSETSTLKEEENEVKSTLE 362
LQ+ P R ++ I N W+QGV P+P + + K+LSE EE N + +
Sbjct: 250 LQRDPKRRASLEEIENHPWLQGVD-PSPATKYNIPLVSYKNLSE-----EEHNSIIQRMV 303
Query: 363 HLGITE-EHIRNNQGRDARSSITGVYRIILHRVQRKK 398
I + + I + + IT Y ++ R+ R+K
Sbjct: 304 LGDIADRDAIVEALETNRYNHITATYFLLAERILREK 340
>gi|156105705 SNF related kinase [Homo sapiens]
Length = 765
Score = 220 bits (561), Expect = 2e-57
Identities = 130/337 (38%), Positives = 195/337 (57%), Gaps = 12/337 (3%)
Query: 68 GKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEK 127
GK G Y + +G G+F+ VKL H T EKVA+K++DKTKLD L +E+ M+
Sbjct: 10 GKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKL 69
Query: 128 LHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKIST-EGKLSEPESKLIFSQIVSAVKH 186
+ HPNI+RLYEV++T +KL+L++E GG++F I E L+E +K F+QIV A+ +
Sbjct: 70 VQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISY 129
Query: 187 MHENQIIHRDLKAENV-FYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDE 245
H+ ++HRDLK ENV F+ VK+ DFGFS + G+ L T CGS Y+APE+ +
Sbjct: 130 CHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGD 189
Query: 246 HYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGV 305
Y VDIW+LGV+L+ +V G PF+ ++ I++ Y+VP HVS+ C LI +
Sbjct: 190 EYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRM 249
Query: 306 LQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQL---DPKHLSETSTLKEEENEVKSTLE 362
LQ+ P R ++ I N W+QGV P+P + + K+LSE EE N + +
Sbjct: 250 LQRDPKRRASLEEIENHPWLQGVD-PSPATKYNIPLVSYKNLSE-----EEHNSIIQRMV 303
Query: 363 HLGITE-EHIRNNQGRDARSSITGVYRIILHRVQRKK 398
I + + I + + IT Y ++ R+ R+K
Sbjct: 304 LGDIADRDAIVEALETNRYNHITATYFLLAERILREK 340
>gi|46877068 AMP-activated protein kinase alpha 2 catalytic subunit
[Homo sapiens]
Length = 552
Score = 213 bits (542), Expect = 3e-55
Identities = 120/324 (37%), Positives = 179/324 (55%), Gaps = 9/324 (2%)
Query: 70 RIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQ-KTQRLLSREISSMEKL 128
+IG Y + +G G F +VK+G H LT KVA+KIL++ K+ + REI +++
Sbjct: 12 KIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 129 HHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMH 188
HP+II+LY+V+ T + +VMEY GGELF I G++ E E++ +F QI+SAV + H
Sbjct: 72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
Query: 189 ENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYI 248
+ ++HRDLK ENV ++ K+ DFG S + GE L T CGSP YAAPE+ Y
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 191
Query: 249 GIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQ 308
G VDIW+ GV+LY ++ GT+PF E V L K I G + +P +++ L+ +LQ
Sbjct: 192 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQV 251
Query: 309 IPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITE 368
P +R I I EW + P F DP + + + + +E VK E TE
Sbjct: 252 DPLKRATIKDIREHEWFK---QDLPSYLFPEDPSY--DANVIDDE--AVKEVCEKFECTE 304
Query: 369 EHIRNN-QGRDARSSITGVYRIIL 391
+ N+ D + + Y +I+
Sbjct: 305 SEVMNSLYSGDPQDQLAVAYHLII 328
>gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic
subunit isoform 1 [Homo sapiens]
Length = 559
Score = 213 bits (541), Expect = 4e-55
Identities = 122/324 (37%), Positives = 183/324 (56%), Gaps = 9/324 (2%)
Query: 70 RIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQ-KTQRLLSREISSMEKL 128
+IG Y + +G G F +VK+G H LT KVA+KIL++ K+ + REI +++
Sbjct: 23 KIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLF 82
Query: 129 HHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMH 188
HP+II+LY+V+ T S + +VMEY GGELF I G+L E ES+ +F QI+S V + H
Sbjct: 83 RHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCH 142
Query: 189 ENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYI 248
+ ++HRDLK ENV ++ K+ DFG S + GE L T CGSP YAAPE+ Y
Sbjct: 143 RHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 202
Query: 249 GIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQ 308
G VDIW+ GV+LY ++ GT+PF + V L K I +G + P +++ L++ +LQ
Sbjct: 203 GPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQV 262
Query: 309 IPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITE 368
P +R I I EW + P F DP S +ST+ ++E +K E +E
Sbjct: 263 DPMKRATIKDIREHEWFK---QDLPKYLFPEDP---SYSSTMIDDE-ALKEVCEKFECSE 315
Query: 369 EHIRN-NQGRDARSSITGVYRIIL 391
E + + R+ + + Y +I+
Sbjct: 316 EEVLSCLYNRNHQDPLAVAYHLII 339
>gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic
subunit isoform 2 [Homo sapiens]
Length = 574
Score = 202 bits (515), Expect = 4e-52
Identities = 122/339 (35%), Positives = 183/339 (53%), Gaps = 24/339 (7%)
Query: 70 RIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQ-KTQRLLSREISSMEKL 128
+IG Y + +G G F +VK+G H LT KVA+KIL++ K+ + REI +++
Sbjct: 23 KIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLF 82
Query: 129 HHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGK---------------LSEPES 173
HP+II+LY+V+ T S + +VMEY GGELF I G+ L E ES
Sbjct: 83 RHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKES 142
Query: 174 KLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGS 233
+ +F QI+S V + H + ++HRDLK ENV ++ K+ DFG S + GE L T CGS
Sbjct: 143 RRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGS 202
Query: 234 PPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPH 293
P YAAPE+ Y G VDIW+ GV+LY ++ GT+PF + V L K I +G + P +
Sbjct: 203 PNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQY 262
Query: 294 VSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEE 353
++ L++ +LQ P +R I I EW + P F DP S +ST+ ++
Sbjct: 263 LNPSVISLLKHMLQVDPMKRATIKDIREHEWFK---QDLPKYLFPEDP---SYSSTMIDD 316
Query: 354 ENEVKSTLEHLGITEEHIRN-NQGRDARSSITGVYRIIL 391
E +K E +EE + + R+ + + Y +I+
Sbjct: 317 E-ALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLII 354
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 200 bits (509), Expect = 2e-51
Identities = 108/337 (32%), Positives = 185/337 (54%), Gaps = 8/337 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
+G YR+ +G G VKLG+H +T +KVAIKI+++ KL + + REI+ ++ + H
Sbjct: 31 VGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEH 90
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
P++++L++V E L+LV+E+ GGELF + +G+L+ E++ F QIVSA+ H
Sbjct: 91 PHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSY 150
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I HRDLK EN+ +++ DFG +++ +L T CGSP YA PE+ + E Y G
Sbjct: 151 SICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGR 210
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
D+W+ GV+L+ ++ G +PF + + +L + + G + +P + C L+RG+++ P
Sbjct: 211 RADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEP 270
Query: 311 TERYGIDCIMNDEWMQGVPY-PTP-LEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITE 368
+R ++ I W G + P P LEP + + E + +V ++ LG
Sbjct: 271 EKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFR 330
Query: 369 EHIRNNQGRDARSSITG----VYRIILHRVQRKKALE 401
+ R R+ RS +Y ++L R +R + E
Sbjct: 331 D--RERLHRELRSEEENQEKMIYYLLLDRKERYPSCE 365
>gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]
Length = 651
Score = 200 bits (509), Expect = 2e-51
Identities = 114/283 (40%), Positives = 168/283 (59%), Gaps = 8/283 (2%)
Query: 73 FYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPN 132
+Y + IG+G F++VKL H LT E VAIKI+DK L R+ + EI +++ L H +
Sbjct: 10 YYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKT-EIEALKNLRHQH 68
Query: 133 IIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQI 192
I +LY V+ET +K+ +V+EY GGELF I ++ +LSE E++++F QIVSAV ++H
Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 128
Query: 193 IHRDLKAENVFYTSNTCVKVGDFGFSTVSK--KGEMLNTFCGSPPYAAPELFRDEHYIGI 250
HRDLK EN+ + +K+ DFG K K L T CGS YAAPEL + + Y+G
Sbjct: 129 AHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 188
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
D+W++G+LLY ++ G +PF + V L K I+ G Y VP +S L++ +LQ P
Sbjct: 189 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDP 248
Query: 311 TERYGIDCIMNDEW-MQGVPYPTPLE---PF-QLDPKHLSETS 348
+R + ++N W MQ YP + PF LD ++E S
Sbjct: 249 KKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELS 291
>gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]
Length = 668
Score = 198 bits (503), Expect = 9e-51
Identities = 105/336 (31%), Positives = 186/336 (55%), Gaps = 8/336 (2%)
Query: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
+G YR+ +G G VKLG+H +T +KVAIKI+++ KL + + REI+ ++ + H
Sbjct: 16 VGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEH 75
Query: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
P++++L++V E L+LV+E+ GGELF + +G+L+ E++ F QI+SA+ H +
Sbjct: 76 PHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSH 135
Query: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
I HRDLK EN+ +++ DFG +++ +L T CGSP YA PE+ R E Y G
Sbjct: 136 SICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGR 195
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
D+W+ GV+L+ ++ G +PF + + +L + + G + +P + C L+RG+++
Sbjct: 196 KADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDA 255
Query: 311 TERYGIDCIMNDEW-MQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEE 369
R ++ I W + G P P +P + + +L++ + +V ++ LG +
Sbjct: 256 ARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQ-IRSLPSLEDIDPDVLDSMHSLGCFRD 314
Query: 370 HIRNNQGRDARSSITG----VYRIILHRVQRKKALE 401
RN +D S +Y ++L R +R + E
Sbjct: 315 --RNKLLQDLLSEEENQEKMIYFLLLDRKERYPSQE 348
>gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
Length = 628
Score = 195 bits (496), Expect = 6e-50
Identities = 108/253 (42%), Positives = 152/253 (60%), Gaps = 3/253 (1%)
Query: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKL-DQKTQRLLSREISSMEKLHHPN 132
Y +G G + +VK S + VAIK + K K+ D++ + REI M L+HP+
Sbjct: 53 YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
Query: 133 IIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQI 192
II ++EV E SK+ +VMEYA G+L+ IS +LSE E++ F QIVSAV + H+N++
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
Query: 193 IHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYV 252
+HRDLK EN+ +N +K+ DFG S + +G+ L TFCGSP YA+PE+ + Y G V
Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
Query: 253 DIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTE 312
D W+LGVLLY +V GTMPF L K I G Y PP S+ C LIR +L PT
Sbjct: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
Query: 313 RYGIDCIMNDEWM 325
R ++ + + W+
Sbjct: 291 RATLEDVASHWWV 303
>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
Length = 661
Score = 192 bits (489), Expect = 4e-49
Identities = 107/253 (42%), Positives = 146/253 (57%), Gaps = 2/253 (0%)
Query: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKL-DQKTQRLLSREISSMEKLHHPN 132
Y ++ +G G + +VK + VAIK + K K+ D++ + REI M L+HP+
Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114
Query: 133 IIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQI 192
II +YEV E K+ ++MEYA GEL+ IS +LSE E++ F QIVSAV + H+N +
Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174
Query: 193 IHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYV 252
+HRDLK EN+ N +K+ DFG S + +K + L TFCGSP YA+PE+ Y G V
Sbjct: 175 VHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEV 234
Query: 253 DIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTE 312
D WALGVLLY +V GTMPF L + I G Y P S+ LIR +L P
Sbjct: 235 DSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSD-ARGLIRWMLMVNPDR 293
Query: 313 RYGIDCIMNDEWM 325
R I+ I N W+
Sbjct: 294 RATIEDIANHWWV 306
>gi|7657214 hormonally upregulated Neu-associated kinase [Homo
sapiens]
Length = 714
Score = 176 bits (445), Expect = 5e-44
Identities = 107/314 (34%), Positives = 169/314 (53%), Gaps = 22/314 (7%)
Query: 62 VREITLGKRIGFYRIRG-EIGSGNFSQVKLGIHSLTKEKVAIKILDK--TKLDQKTQRLL 118
+R+ KR+G Y I ++G G+F++V+ G+H LT EKVAIK++DK K D + L
Sbjct: 49 LRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNL 108
Query: 119 SREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFS 178
RE + + HPNI +L +++ET + +LVME GG L KI + +L E E++
Sbjct: 109 RREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIR 168
Query: 179 QIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFST---VSKKGEMLNTFCGSPP 235
Q++SAV+H+H ++HRDLK EN+ + +K+ DFG S + + +T CGSP
Sbjct: 169 QLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPA 228
Query: 236 YAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETV---AKLKKSILEGTYSVPP 292
YAAPEL + Y G +D+W++GV +Y M+TGT+PF E A +K + + +P
Sbjct: 229 YAAPELLARKKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPT 287
Query: 293 HVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQ---------GVPYPTPLEPFQLDPK- 342
+S +R +L+ P +R I + + W+ V YP + L P
Sbjct: 288 QLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSV 347
Query: 343 --HLSETSTLKEEE 354
H++E K +
Sbjct: 348 VLHMTEKLGYKNSD 361
>gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform a [Homo sapiens]
Length = 426
Score = 164 bits (414), Expect = 2e-40
Identities = 101/282 (35%), Positives = 153/282 (54%), Gaps = 15/282 (5%)
Query: 53 QDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQ 112
QDM +K +I+ Y IR +GSG FS+V L + VA+K + K L
Sbjct: 82 QDMLLLKKHTEDIS-----SVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRG 136
Query: 113 KTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPE 172
K + L+ EI+ + ++ HPNI+ L +V E+ S L+L ME GGELF +I G +E +
Sbjct: 137 K-EALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKD 195
Query: 173 SKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTS---NTCVKVGDFGFSTVSKKGEMLNT 229
+ + Q++ AV ++H I+HRDLK EN+ Y + ++ + V DFG S + + G ML T
Sbjct: 196 ASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGT 254
Query: 230 FCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYS 289
CG+P Y APEL + Y G VD+WALGV+ Y ++ G PF E+ +L IL +Y
Sbjct: 255 ACGTPGYVAPELLEQKPY-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYE 313
Query: 290 VP----PHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQG 327
+SE IR +L++ P +R+ + W+ G
Sbjct: 314 FDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISG 355
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 164 bits (414), Expect = 2e-40
Identities = 92/255 (36%), Positives = 149/255 (58%), Gaps = 11/255 (4%)
Query: 80 IGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEV 139
+GSG FS+V L LT + A+K + K+ + + L EI+ ++K+ H NI+ L ++
Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSS--LENEIAVLKKIKHENIVTLEDI 86
Query: 140 VETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKA 199
E+ + +LVM+ GGELF +I G +E ++ L+ Q++SAVK++HEN I+HRDLK
Sbjct: 87 YESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKP 146
Query: 200 ENVFYTS---NTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWA 256
EN+ Y + N+ + + DFG S + + G +++T CG+P Y APE+ + Y VD W+
Sbjct: 147 ENLLYLTPEENSKIMITDFGLSKMEQNG-IMSTACGTPGYVAPEVLAQKPY-SKAVDCWS 204
Query: 257 LGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVP----PHVSEPCHRLIRGVLQQIPTE 312
+GV+ Y ++ G PF ET +KL + I EG Y +SE I +L++ P E
Sbjct: 205 IGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNE 264
Query: 313 RYGIDCIMNDEWMQG 327
RY + ++ W+ G
Sbjct: 265 RYTCEKALSHPWIDG 279
>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform b [Homo sapiens]
Length = 360
Score = 163 bits (413), Expect = 2e-40
Identities = 96/261 (36%), Positives = 145/261 (55%), Gaps = 10/261 (3%)
Query: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNI 133
Y IR +GSG FS+V L + VA+K + K L K + L+ EI+ + ++ HPNI
Sbjct: 32 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGK-EALVENEIAVLRRISHPNI 90
Query: 134 IRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQII 193
+ L +V E+ S L+L ME GGELF +I G +E ++ + Q++ AV ++H I+
Sbjct: 91 VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 150
Query: 194 HRDLKAENVFYTS---NTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
HRDLK EN+ Y + ++ + V DFG S + + G ML T CG+P Y APEL + Y G
Sbjct: 151 HRDLKPENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVAPELLEQKPY-GK 208
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVP----PHVSEPCHRLIRGVL 306
VD+WALGV+ Y ++ G PF E+ +L IL +Y +SE IR +L
Sbjct: 209 AVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLL 268
Query: 307 QQIPTERYGIDCIMNDEWMQG 327
++ P +R+ + W+ G
Sbjct: 269 ERDPQKRFTCQQALRHLWISG 289
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 160 bits (406), Expect = 2e-39
Identities = 89/261 (34%), Positives = 149/261 (57%), Gaps = 9/261 (3%)
Query: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNI 133
Y R +G+G FS+V L T++ VAIK + K L+ K + + EI+ + K+ HPNI
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGK-EGSMENEIAVLHKIKHPNI 78
Query: 134 IRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQII 193
+ L ++ E+ L+L+M+ GGELF +I +G +E ++ + Q++ AVK++H+ I+
Sbjct: 79 VALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIV 138
Query: 194 HRDLKAENVFYTS---NTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
HRDLK EN+ Y S ++ + + DFG S + G +L+T CG+P Y APE+ + Y
Sbjct: 139 HRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY-SK 197
Query: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVP----PHVSEPCHRLIRGVL 306
VD W++GV+ Y ++ G PF E AKL + IL+ Y +S+ IR ++
Sbjct: 198 AVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLM 257
Query: 307 QQIPTERYGIDCIMNDEWMQG 327
++ P +R+ + + W+ G
Sbjct: 258 EKDPEKRFTCEQALQHPWIAG 278
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,636,922
Number of Sequences: 37866
Number of extensions: 735338
Number of successful extensions: 4291
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 712
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 2028
Number of HSP's gapped (non-prelim): 976
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.