Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 23111062
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23111062 splicing factor, arginine/serine-rich 8 [Homo
sapiens]
(951 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 1886 0.0
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 97 5e-20
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 93 1e-18
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 92 2e-18
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 92 2e-18
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 83 1e-15
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 83 1e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 81 4e-15
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 80 1e-14
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 77 6e-14
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 77 8e-14
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 77 1e-13
gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo... 75 2e-13
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 75 2e-13
gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Hom... 75 4e-13
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 74 6e-13
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 74 6e-13
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 74 6e-13
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 73 1e-12
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 73 1e-12
gi|122937227 U2-associated SR140 protein [Homo sapiens] 73 1e-12
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 73 1e-12
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 73 1e-12
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 72 2e-12
gi|50962882 G patch domain containing 8 [Homo sapiens] 72 2e-12
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 70 7e-12
gi|50083281 KIAA1853 protein [Homo sapiens] 70 9e-12
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 68 5e-11
gi|116812577 LUC7-like 2 [Homo sapiens] 67 8e-11
gi|52426743 cisplatin resistance-associated overexpressed protei... 67 8e-11
>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
Length = 951
Score = 1886 bits (4885), Expect = 0.0
Identities = 951/951 (100%), Positives = 951/951 (100%)
Query: 1 MYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHL 60
MYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHL
Sbjct: 1 MYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHL 60
Query: 61 IPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHT 120
IPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHT
Sbjct: 61 IPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHT 120
Query: 121 DLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAEN 180
DLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAEN
Sbjct: 121 DLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAEN 180
Query: 181 LEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQF 240
LEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQF
Sbjct: 181 LEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQF 240
Query: 241 DFLRFDHYLNPYYKFIQKAMKEGRYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPS 300
DFLRFDHYLNPYYKFIQKAMKEGRYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPS
Sbjct: 241 DFLRFDHYLNPYYKFIQKAMKEGRYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPS 300
Query: 301 LFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPSQVEYTAD 360
LFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPSQVEYTAD
Sbjct: 301 LFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPSQVEYTAD 360
Query: 361 STVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTP 420
STVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTP
Sbjct: 361 STVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTP 420
Query: 421 LPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRA 480
LPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRA
Sbjct: 421 LPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRA 480
Query: 481 KNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDG 540
KNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDG
Sbjct: 481 KNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDG 540
Query: 541 APEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKL 600
APEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKL
Sbjct: 541 APEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKL 600
Query: 601 DDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLA 660
DDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLA
Sbjct: 601 DDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLA 660
Query: 661 AAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTP 720
AAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTP
Sbjct: 661 AAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTP 720
Query: 721 CPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKS 780
CPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKS
Sbjct: 721 CPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKS 780
Query: 781 RSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRK 840
RSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRK
Sbjct: 781 RSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRK 840
Query: 841 RTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGS 900
RTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGS
Sbjct: 841 RTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGS 900
Query: 901 SQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS 951
SQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS
Sbjct: 901 SQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS 951
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 97.4 bits (241), Expect = 5e-20
Identities = 96/317 (30%), Positives = 142/317 (44%), Gaps = 51/317 (16%)
Query: 630 PCVVVEEKKPQLTQEELEA-KQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAA 688
P +E KK ++ Q ++E K A K +D ++ ++S+E +E+ R++ +
Sbjct: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRS 179
Query: 689 LFLQTLKNPLPEAEAGKIEESP-FSVEESSTTPCPLL---TGGRPLPTLEVKPPDRPSSK 744
+ +P+ SP + S +P P T P P+++VK P +
Sbjct: 180 PSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEAT 239
Query: 745 SKDP------------PREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSL 792
S P+E EK KK K++ +TR RS S SKSRSR+ S++
Sbjct: 240 STSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRS---RSRSKSRSRTRSRS---- 292
Query: 793 PSAYRTVRRSRSRSR--SPRRRAH-----SPERRREERSV--PTAYRVSRSPGASRKR-- 841
PS R RR RSRSR SPRRR SP RR R + P +R SRSP R+R
Sbjct: 293 PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS 352
Query: 842 ------------TRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQ--AAPRPAAPAAHSA 887
+RSRSP +K KR S K++ S S SP ++ PA P +
Sbjct: 353 ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412
Query: 888 HSASVSPVESRGSSQER 904
HS +P +S + + R
Sbjct: 413 HSP--TPQQSNRTRKSR 427
Score = 69.7 bits (169), Expect = 1e-11
Identities = 108/533 (20%), Positives = 191/533 (35%), Gaps = 37/533 (6%)
Query: 393 YSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAPVAAIIPP 452
+S P T S SP + AP TP P + + + T+TS + V P
Sbjct: 197 HSRSPRHRTKSRSP---SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPI 253
Query: 453 PPDVQPVIDKLA-EYVARNGLKFETSVRAKNDQRFEFLQPWH-QYNAYYEFKKQFFLQKE 510
P +P +K + + + + + R+K+ R P H + + + + + +
Sbjct: 254 PEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR 313
Query: 511 GGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGK 570
+ S P P P A +SS P K
Sbjct: 314 RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK 373
Query: 571 LVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPP 630
K + +P + + P ++R + S+ + +V+P
Sbjct: 374 PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPG 433
Query: 631 CVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAARE---KLAQASKESKEKQLQAERKRK- 686
+ K + T++ A + + L+ + + K+A A + +Q + + ++
Sbjct: 434 RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSS 493
Query: 687 ----AALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPS 742
++ + + + G++ S +P P E P R
Sbjct: 494 SDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKR------QKETSPRGRRR 547
Query: 743 SKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHS-SSKSRSRSHSKAKHSLPSAYRTVRR 801
PP + +R RT + P+ + S R RS S ++S P ++R
Sbjct: 548 RSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP-----IQR 602
Query: 802 SRSRSRSPRRRAHS---PERRREERSVPTAYRVSRSPGASRKR---TRSRSPHEKKKKRR 855
S S P+RR S P +RR S P RVS SP ++ T+ RSP K R+
Sbjct: 603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRK 662
Query: 856 SRSRTKSKARSQSVSPSKQ--AAPRPAAPAAHSAHSASVSPVESRGSSQERSR 906
S ++S ++S P+K+ +PRP AP S+S PV SS + R
Sbjct: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQT----SSSPPPVRRGASSSPQRR 711
Score = 58.5 bits (140), Expect = 3e-08
Identities = 78/328 (23%), Positives = 117/328 (35%), Gaps = 26/328 (7%)
Query: 611 KEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAK----QAKQKLEDRLAAAAREK 666
++ S S T P +EK P+L + ++ K Q D L E
Sbjct: 193 RKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP 252
Query: 667 LAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTG 726
+ + + S EK + E++++ K K S S T P
Sbjct: 253 IPEPKEPSPEKNSKKEKEKE--------KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRS 304
Query: 727 GRPL--PTLEVKPPDRPSSKSKDPPRE-----EEKEKKKKKHKKRSRTRSRSPKYHSSSK 779
P P RPS + + PPR + + ++R + S S SSS
Sbjct: 305 RSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSS 364
Query: 780 SRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASR 839
SRSRS K S+ R S S SP RR H P + P R S +P S
Sbjct: 365 SRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS---PPATPPPKTRHSPTPQQSN 421
Query: 840 KRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRG 899
+ +SR R S TK K + SPS AP+P + + +
Sbjct: 422 RTRKSRV--SVSPGRTSGKVTKHKGTEKRESPS--PAPKPRKVELSESEEDKGGKMAAAD 477
Query: 900 SSQERSRGVSQEKEAQISSAIVSSVQSK 927
S Q+R + Q +++ S SS + +
Sbjct: 478 SVQQRRQYRRQNQQSSSDSGSSSSSEDE 505
Score = 55.8 bits (133), Expect = 2e-07
Identities = 82/328 (25%), Positives = 126/328 (38%), Gaps = 55/328 (16%)
Query: 616 SSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESK 675
SSSS+ + +P PP P L + + R + A ++ S
Sbjct: 361 SSSSSRSRSPPKKPP---KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP--PKTRHSP 415
Query: 676 EKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEV 735
Q Q+ R RK+ + + P +GK+ + + + S +P P
Sbjct: 416 TPQ-QSNRTRKSRVSVS------PGRTSGKVTKHKGTEKRESPSPAP------------- 455
Query: 736 KPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSA 795
+P E++ K + R + R SSS S S S S+ + S
Sbjct: 456 ----KPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSH 511
Query: 796 YRTVRRSRSRSRSPRRRAH-SPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKR 854
+ R R SP R A SP +R++E S R S SP +R+R RS SP ++R
Sbjct: 512 VKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRR-RSPSPAPPPRRR 570
Query: 855 RS-----RSRTKS-KARSQSVSPSKQAAP-------------RPAAPAAHSAHSASVSPV 895
R+ R RT S R +S SP + + P R A+P AS SP
Sbjct: 571 RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP 630
Query: 896 ESRGSS-----QERSRGVSQEKEAQISS 918
R S ++RS V++ + +SS
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSS 658
Score = 53.9 bits (128), Expect = 7e-07
Identities = 76/332 (22%), Positives = 126/332 (37%), Gaps = 60/332 (18%)
Query: 611 KEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQA 670
++ Q+SSS + +++ + E+++P+ + K R + + A
Sbjct: 487 RQNQQSSSDSGSSSSS--------EDERPKRSH-------VKNGEVGRRRRHSPSRSASP 531
Query: 671 SKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPL 730
S ++K+ +R+ ++P P + SP TP P P
Sbjct: 532 SPRKRQKETSPRGRRR--------RSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPS 583
Query: 731 PTLEVKPPDR----------------PSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKY 774
P + P P ++ PP ++ KR + S PK
Sbjct: 584 PPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQ 643
Query: 775 HSSSKSRSRSHS-KAKHSLPSAYRTVRRSRSRSRSPR-RRAHSPERR-REERSVPTAYRV 831
SS ++ RS S +KH S+ RS +RSP+ + HSP R R ++ + V
Sbjct: 644 RSSPVTKRRSPSLSSKHRKGSS---PSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700
Query: 832 SRSPGASRKRTRSRSPH-----------EKKKKRRSRSRTKSKARSQSVSPSKQAAPRPA 880
R +S +R +S SP E KK +++ S + R S S S +P PA
Sbjct: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760
Query: 881 APAAHSAHSASVSPVESRGSSQERSRGVSQEK 912
A A SPV+S+ S S V +K
Sbjct: 761 A----KKPPAPPSPVQSQSPSTNWSPAVPVKK 788
Score = 50.1 bits (118), Expect = 1e-05
Identities = 50/190 (26%), Positives = 83/190 (43%), Gaps = 11/190 (5%)
Query: 715 ESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKY 774
++S++P P+ G P P S S P R + + KK KK + +S +
Sbjct: 692 QTSSSPPPVRRGASSSPQRRQSP-----SPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746
Query: 775 HSSSKSRSRSHSKAKHSLPSAYRTVR-RSRSRSRSPRRRAHSPERRREERSVPTAYRVSR 833
SSS+S S S A P+ V+ +S S + SP A ++ + P+ R S
Sbjct: 747 VSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSP---AVPVKKAKSPTPSPSPPRNSD 803
Query: 834 SPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVS 893
G +K+ + + KK K+ + + K ++ V+ + AA PAA AA + A
Sbjct: 804 QEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKA--VAAAAAAAVTPAAIAAATTTLAQEE 861
Query: 894 PVESRGSSQE 903
PV + +E
Sbjct: 862 PVAAPEPKKE 871
Score = 36.2 bits (82), Expect = 0.15
Identities = 44/222 (19%), Positives = 81/222 (36%), Gaps = 21/222 (9%)
Query: 610 SKEGQESSSSAANT--NPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAR-EK 666
S+ +E+ S N +P+ P P + + + Q +Q R +
Sbjct: 667 SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
Query: 667 LAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTG 726
+ K K + R+ + +P P A+ SP + ST P +
Sbjct: 727 TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAV-- 784
Query: 727 GRPLPTLEVKPPDRPSSKSKDPPREEEKE----KKKKKHKKRSRTRSRSPKYHSSSKSRS 782
P + K P + S PPR ++E KKKKK K+ + + K+ K ++
Sbjct: 785 ----PVKKAKSP----TPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKA 836
Query: 783 RSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERS 824
+ + A P+A + ++ +PE ++E S
Sbjct: 837 VAAAAAAAVTPAAIAAATTTLAQEEP----VAAPEPKKETES 874
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 92.8 bits (229), Expect = 1e-18
Identities = 74/203 (36%), Positives = 106/203 (52%), Gaps = 20/203 (9%)
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
R S+S+ P + ++ + + +K R +RSRSP Y + +SRSRS +KA+ S
Sbjct: 411 RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSP-YKARDRSRSRSPNKARDHSRSRSPNK 469
Query: 800 RRSRSRSRSP-RRRAHS----PERRREER-----SVPTAYRVSRSPGASRKRTRSRSPHE 849
R RSRSRSP + R HS P + R+ R S R SRS R RSRSP +
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSK 529
Query: 850 KKKKRRSRSRTKSKARSQSVSPSKQAAPRPA-APAAHSAHSASVSPV------ESRGSSQ 902
++++R+SRS K + RSQS SPS++ R + +P+ SP +SR SS+
Sbjct: 530 ERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSE 589
Query: 903 ER--SRGVSQEKEAQISSAIVSS 923
ER SR S K++ S SS
Sbjct: 590 ERDHSRSRSPNKQSGYSRPRASS 612
Score = 80.9 bits (198), Expect = 5e-15
Identities = 92/358 (25%), Positives = 141/358 (39%), Gaps = 66/358 (18%)
Query: 637 KKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKN 696
+ P + ++ + ++ + R +++ R++ ++ S KQ R R ++
Sbjct: 357 RNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRS 416
Query: 697 PLP-EAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPD----------RPSSKS 745
P +A SP + S + P R K D R S+S
Sbjct: 417 RSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRS 476
Query: 746 KDPPREEEKEKKKKKHKKRSRTRSRSP-------KYHSSSKSR----SRSHSKAKHSLPS 794
+ P +E + + K+R RSRSP + SSSK R SRS SK + S
Sbjct: 477 RSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQS 536
Query: 795 AYRTVRRSRSRSRSP-----RRRAHSPERRREER-----SVPTAYRVSRSPGASRKRTRS 844
R RS+SRSP R++ SP + R+ R S R SRS R +RS
Sbjct: 537 RSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRS 596
Query: 845 RSPHEK----------KKKRRSRSRTKSKARSQSVS--------PSKQAAPRP------- 879
RSP+++ K+K SRSRT SK + S S PS+ PR
Sbjct: 597 RSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSP 656
Query: 880 ---------AAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAIVSSVQSKI 928
P+ S+HS S P + SQ+ S+ + +A + SS SK+
Sbjct: 657 TRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKL 714
Score = 75.1 bits (183), Expect = 3e-13
Identities = 75/235 (31%), Positives = 108/235 (45%), Gaps = 40/235 (17%)
Query: 715 ESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKR--------SR 766
E S +P + + + + + S+S+ P R +K+ + R SR
Sbjct: 254 EKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSR 313
Query: 767 TRSRSPK---YHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSR--SRSP-RRRAHSPERR- 819
RSR+ K S+SRSHSK K S RT RR RS SR+P + R+HS R
Sbjct: 314 ARSRTRKGILSQMGRHSQSRSHSKGKSQNQS--RTPRRGRSHNWSRNPSKERSHSHSRSS 371
Query: 820 -----------------REERSVPTAYR---VSRSPGASRKRTRSRSPHEKKKKRRSRSR 859
R + P R SRSP +R R+RSRSP++ + + RSRS
Sbjct: 372 SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSP 431
Query: 860 TKSKARSQSVSPSK-QAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKE 913
K++ S+S SP K + R +P HS S SP ++R S RSR S+E++
Sbjct: 432 NKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRS--RSRSPSKERD 484
Score = 55.5 bits (132), Expect = 2e-07
Identities = 63/199 (31%), Positives = 80/199 (40%), Gaps = 30/199 (15%)
Query: 712 SVEESSTTPCPLLTGGRPLPTLEVKPP-DRPSSKSKDPPREEEKEKKKKKHKKRSRTRSR 770
S + SS L G +PT + KPP S+KS P R K SR
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPAT-----SRNSVM 57
Query: 771 SPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYR 830
SP SS ++S S +A + PS SRSR RS +A +P R V T R
Sbjct: 58 SPS--SSKSTKSTSTKRAPSNRPS-------SRSRVRS---KARTPSR------VSTDTR 99
Query: 831 VSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSA 890
S++ AS R R + SR RT + S+S S A P H A
Sbjct: 100 TSKASKASDVRCHQR------RGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPG 153
Query: 891 SVSPVESRGSSQERSRGVS 909
S V + S Q+ SRG S
Sbjct: 154 MASRVRTPTSQQKGSRGKS 172
Score = 53.9 bits (128), Expect = 7e-07
Identities = 51/176 (28%), Positives = 81/176 (46%), Gaps = 21/176 (11%)
Query: 737 PPDRPSSKSKDPPREEEKEKKKKKHKK--RSRTRSRSPKYHSSSKSRSRSHSKAKHSLPS 794
P PS + D P K K + SR +S SP + SR +S+++A
Sbjct: 222 PTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSP---TEMSSRVKSYNQA------ 272
Query: 795 AYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKR 854
+ R+ +S S+SRSPRR ++R R +++ + S R R+R+R + R
Sbjct: 273 STRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHS----RARSRTRKGILSQMGR 328
Query: 855 RSRSRTKSKARSQSVS------PSKQAAPRPAAPAAHSAHSASVSPVESRGSSQER 904
S+SR+ SK +SQ+ S S + P+ +HS +S + RGSS R
Sbjct: 329 HSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR 384
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 92.0 bits (227), Expect = 2e-18
Identities = 72/206 (34%), Positives = 105/206 (50%), Gaps = 36/206 (17%)
Query: 742 SSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSS----KSRSRSHS----------- 786
SS SK R + + K + RS++RSRS K S S KSRSRSHS
Sbjct: 213 SSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQ 272
Query: 787 ------------KAKHSLPSAYRTVRRSRSRSRSPRRRAHSPER------RREERSVPTA 828
K K PS +++ +S+SRSRS RR +R R +E+S+ +
Sbjct: 273 AEEKIQNNDNVGKPKSRSPSRHKS--KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
Query: 829 YRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAH 888
SRS G SR R+RSRS + K+K R RSR +S++RS+S S S+++ R + + +
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS 390
Query: 889 SASVSPVES-RGSSQERSRGVSQEKE 913
S ++ R S+ SR VS+E+E
Sbjct: 391 SKKKKKEDTDRSQSRSPSRSVSKERE 416
Score = 78.2 bits (191), Expect = 3e-14
Identities = 62/202 (30%), Positives = 99/202 (49%), Gaps = 31/202 (15%)
Query: 727 GRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKY-HSSSKSRSRSH 785
GR + +E KP R +S R + + + +H ++SR+RS S K HS S+SRSRS
Sbjct: 167 GRKIRLVEDKPGSR-RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225
Query: 786 SKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSR 845
S+++ S RS+SRSRS + ++ SP + + SRS A + R++S+
Sbjct: 226 SRSRSKSRS------RSQSRSRSKKEKSRSPSKEKSR---------SRSHSAGKSRSKSK 270
Query: 846 SPHEKK-----------KKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSA---S 891
E+K + SR ++KSK+RS+S + R + S + S
Sbjct: 271 DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
Query: 892 VSPVESRGSSQERSRGVSQEKE 913
S S+G S+ RSR S+ K+
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKD 352
Score = 72.4 bits (176), Expect = 2e-12
Identities = 62/180 (34%), Positives = 88/180 (48%), Gaps = 40/180 (22%)
Query: 755 EKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAH 814
E K ++RS +RSRS HS S+SRSR K++ S+ + +SRSRSRS R
Sbjct: 174 EDKPGSRRRRSYSRSRS---HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR--- 227
Query: 815 SPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEK-----KKKRRSRSRTKSKARSQSV 869
SRS SR ++RSRS EK K+K RSRS + K+RS+S
Sbjct: 228 -----------------SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSK 270
Query: 870 SPSKQ--------AAPRPAAPAAHSAHSASVSPVESRGSSQER----SRGVSQEKEAQIS 917
+++ P+ +P+ H + S S S + R +E+ SRG SQEK + S
Sbjct: 271 DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
Score = 68.6 bits (166), Expect = 3e-11
Identities = 64/193 (33%), Positives = 94/193 (48%), Gaps = 33/193 (17%)
Query: 743 SKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSS-SKSRSRSHSKAKHSLP-------- 793
SKSKD + E+K + + + +SRSP H S SKSRSRS +
Sbjct: 267 SKSKD-----QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGR 321
Query: 794 SAYRTVRRSRSRSRS---PRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEK 850
S +++R+SRSRSRS R R+ S + +++R RS SR R+RSRS E+
Sbjct: 322 SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK-----GRKRSREESRSRSRSRSKSER 376
Query: 851 KKKRRSRSRTKSKA----------RSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGS 900
+KR S+ +K+ + RSQS SPS+ + + S+ E+ G+
Sbjct: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
Query: 901 SQE-RSRGVSQEK 912
+QE RSR S K
Sbjct: 437 NQETRSRSRSNSK 449
Score = 66.6 bits (161), Expect = 1e-10
Identities = 54/170 (31%), Positives = 76/170 (44%), Gaps = 24/170 (14%)
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
R S+SK R + + K K K++ R RSR S+SRSRS SK++ S +
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSR-----EESRSRSRSRSKSERSRKRGSKRD 385
Query: 800 RRS------------RSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSP 847
++ RS+SRSP R + S R + + TRSRS
Sbjct: 386 SKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSR 445
Query: 848 HEKKKK------RRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSAS 891
K K RSRS++ SK RS+S S S+ A+ P+ + S HS S
Sbjct: 446 SNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS-HSRS 494
Score = 63.9 bits (154), Expect = 7e-10
Identities = 49/159 (30%), Positives = 80/159 (50%), Gaps = 11/159 (6%)
Query: 736 KPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSA 795
K R S+S+ +++ K +K+ + + RSR+RSRS K S K S+ SKA S
Sbjct: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS-KSERSRKRGSKRDSKAGSSKKKK 395
Query: 796 YRTVRRSRSRSRS-----PRRRAHSPERRREERSVPT---AYRVSRSPGASRKRTRSRSP 847
RS+SRS S R A S +RE R + +RS S +++ P
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
Query: 848 HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHS 886
E + + +S S+T+S+++S+S S S+ +P + +HS
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASR--SPSRSRSRSHS 492
Score = 55.8 bits (133), Expect = 2e-07
Identities = 54/229 (23%), Positives = 97/229 (42%), Gaps = 46/229 (20%)
Query: 633 VVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQ 692
V EEK+ +++ + K +Q + +++ +SK+K+ +R R+ + +
Sbjct: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES---R 365
Query: 693 TLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREE 752
+ ++E + S + S+ + K D S+S+ P R
Sbjct: 366 SRSRSRSKSERSRKRGSKRDSKAGSSK--------------KKKKEDTDRSQSRSPSRSV 411
Query: 753 EKEK---KKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSP 809
KE+ K + ++ R S + + ++SRSRS+SK+K +LPS SRSRS+S
Sbjct: 412 SKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPS------ESRSRSKSA 465
Query: 810 RRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRS 858
+ +RS SR R+ SRSP + + SRS
Sbjct: 466 SK--------------------TRSRSKSRSRSASRSPSRSRSRSHSRS 494
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 92.0 bits (227), Expect = 2e-18
Identities = 94/333 (28%), Positives = 145/333 (43%), Gaps = 40/333 (12%)
Query: 601 DDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEK---KPQ------LTQEELEAKQA 651
D D D E+S S ++T P P ++ E+ PQ L+QE +
Sbjct: 337 DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396
Query: 652 KQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPF 711
DR + EKL Q+S S E + + K + ++ E+ K +P
Sbjct: 397 ASPTRDRSPPKSPEKLPQSS--SSESSPPSPQPTKVS------RHASSSPESPKPAPAPG 448
Query: 712 SVEESSTTPCPL-LTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSR 770
S E S++P + GR R S S P R + + KR R+RSR
Sbjct: 449 SHREISSSPTSKNRSHGRA---------KRDKSHSHTPSRRMGRSRSPAT-AKRGRSRSR 498
Query: 771 SPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRR----RAHSPERRREERSVP 826
+P S+SRS +++ + + R RSRSP+R R+ + +RR RS
Sbjct: 499 TPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR 558
Query: 827 TAYRVSRSPGASRKRTRSRSPHEKKK-------KRRSRSRTKSKARSQSVSPSKQAAPRP 879
SRSP A+R R+RSR+P + + +RRSRSRT ++ RS+S +P+++ R
Sbjct: 559 RGRSHSRSP-ATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617
Query: 880 AAPAAHSAHSASVSPVESRGSSQERSRGVSQEK 912
PA + + S SR S R G S+ +
Sbjct: 618 RTPARRRSRTRSPVRRRSRSRSPARRSGRSRSR 650
Score = 81.6 bits (200), Expect = 3e-15
Identities = 109/441 (24%), Positives = 176/441 (39%), Gaps = 65/441 (14%)
Query: 527 DSAPEK---PSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAI 583
DS+PE P + E+ + + ++ + S +V + + S +
Sbjct: 1481 DSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSG 1540
Query: 584 KAKENDLLPLEKNRVKLDDDSDDDEESKEGQE-SSSSAANTNPAVAPPCVVVEEKKPQLT 642
++E D+ P + + + DS D ++K S + ++P V + K +L+
Sbjct: 1541 SSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV--------DSKSRLS 1592
Query: 643 QEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAE 702
+ + + + AA + + +S E K +A +R + + P PE
Sbjct: 1593 PRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGS 1652
Query: 703 AGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVK---PPDRPSSKSK-DPPREEEKEKKK 758
+ E SP +S T G R P + K PP R SS+S + R+ ++
Sbjct: 1653 SST-ESSPEHPPKSRTAR----RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
Query: 759 KKHKKRSRTRSRSPKYHSSS----------KSRSRSHSKAKHSLPSAYRTVRRSRSRSRS 808
+ TRSR+P H S KSRS S + S P T RR RS S
Sbjct: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS-SRRRRSASSPRTKTTSRRGRSPSPK 1766
Query: 809 PR--RRAHSPERRREERSVPTAYRVSRSPGASRKRTRSR--------------------- 845
PR +R+ S RR + R+ R S SR+R RSR
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA 1826
Query: 846 ---SPHEKKKKRRSRSRTKSKARSQSVS-----PSKQAAPRPAAPAAHSAHSASVSPVES 897
S ++RR RSRT +R +S S P K++ R A+PA H S S +P+ S
Sbjct: 1827 RQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR-ASPATH-RRSRSRTPLIS 1884
Query: 898 RGSSQERSRGVSQEKEAQISS 918
R S+ R+ VS+ + +S
Sbjct: 1885 RRRSRSRTSPVSRRRSRSRTS 1905
Score = 81.3 bits (199), Expect = 4e-15
Identities = 108/430 (25%), Positives = 160/430 (37%), Gaps = 53/430 (12%)
Query: 509 KEGGDSMQAVSAPE-EAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVP 567
+ G S +PE + T+S+PE P + AR GS E + P
Sbjct: 1637 RSGSSSKGRGPSPEGSSSTESSPEHPPKSRT-----------ARRGSRSSPEPKTKSRTP 1685
Query: 568 DGKLVKASFAPIS----FAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANT 623
+ S ++ + +++ P ++R S E E S S+
Sbjct: 1686 PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR 1745
Query: 624 NPAVAPPCVVVEEK--KPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQA 681
A +P + P L+ +++ + E R++ + S+ +Q
Sbjct: 1746 RSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR 1805
Query: 682 ERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRP 741
R R +G SP E S T+ R PT + R
Sbjct: 1806 SRSRVTRR---------RRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT 1856
Query: 742 S------SKSKDPPREEEKEKKK----KKHKKRSRT----RSRSPKYHSSSKSRSRSHSK 787
S S+S+ P + + + + + RSRT R RS S ++ RSRS +
Sbjct: 1857 SPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRAS 1916
Query: 788 AKHSLPSAYRT--VRRSRSRSRSP--RRRAHS-----PERRREERSVPTAYRVSRSPGAS 838
S RT V R RSRSR+P RRR+ S RR R+ P R SRS +
Sbjct: 1917 PVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP 1976
Query: 839 RKRTRSRSPHEKKKKRRSRSRTKSKARSQS---VSPSKQAAPRPAAPAAHSAHSASVSPV 895
R RSRS +RRSRSRT R +S SP + R P A S S +P+
Sbjct: 1977 ITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPL 2036
Query: 896 ESRGSSQERS 905
R S+ RS
Sbjct: 2037 LPRKRSRSRS 2046
Score = 80.5 bits (197), Expect = 7e-15
Identities = 95/431 (22%), Positives = 168/431 (38%), Gaps = 45/431 (10%)
Query: 507 LQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTV 566
++K G S Q++S+P D+ P PS A + G + + SS +
Sbjct: 1391 VEKAGMSSNQSISSPV---LDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGL 1447
Query: 567 PDGKLVKASFAPISFAIKAKENDL--LPLEKNRVKLDDDSDDDEESKEGQESSSSAANTN 624
DG S P ++ + +P +R + + DS + ++ S + ++
Sbjct: 1448 RDG-----SGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSS 1502
Query: 625 PAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAER- 683
P + C+ + ++ + A+ L R + + ++L S +++ +++
Sbjct: 1503 PELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSS 1562
Query: 684 -----KRKAALFLQTLKNPLPEAEA------------------GKIEESPFSVEESSTTP 720
K + L ++ PE ++ K +P + S ++P
Sbjct: 1563 PDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSP 1622
Query: 721 CPLLTGGRPLPTLEVKPPDRPSSKSKDP-PREEEKEKKKKKHKKRSRTRSRSPKYHSSSK 779
P R LP + SSK + P P + +H +SRT R + K
Sbjct: 1623 EPKAPAPRALPR---RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPK 1679
Query: 780 SRSRS-----HSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRS 834
++SR+ S++ L R RRSRS S SP R+ +P R R SV + +S
Sbjct: 1680 TKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKS 1739
Query: 835 PGASRKRTRSRSPHEKKKKRRSRSRT-KSKARSQSVSPSKQAAPRPAAPAAHSAHSASVS 893
+ R+R+ S SP K RR RS + K + +S S S++ R S S S S
Sbjct: 1740 RSSRRRRSAS-SPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTS 1798
Query: 894 PVESRGSSQER 904
R S+ R
Sbjct: 1799 RRRQRSRSRSR 1809
Score = 78.6 bits (192), Expect = 3e-14
Identities = 65/220 (29%), Positives = 106/220 (48%), Gaps = 20/220 (9%)
Query: 737 PPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAY 796
P R S+S+ P R + + + + RSRT +R + S + +R RS +++ S
Sbjct: 578 PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS 637
Query: 797 RT-VRRS-RSRSRSPRRR----AHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEK 850
R+ RRS RSRSR+P RR + +P RR R SR+P R+RSR+P
Sbjct: 638 RSPARRSGRSRSRTPARRGRSRSRTPARRGRSR--------SRTPARRSGRSRSRTP--- 686
Query: 851 KKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQ 910
++ RSRSRT + RS+S S ++ P +S +SQ RSR S
Sbjct: 687 ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNS- 745
Query: 911 EKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSA 950
++ + +SS +S+ +K ++ L+ ++L S+
Sbjct: 746 --SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783
Score = 76.6 bits (187), Expect = 1e-13
Identities = 97/467 (20%), Positives = 178/467 (38%), Gaps = 67/467 (14%)
Query: 508 QKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVP 567
+ G S + P +P + + SD+ D + + R+ SG E S +
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSE---SDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLS 1592
Query: 568 DGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQ----ESSSSAANT 623
+ S S +K K P R + DS + ++ + S S +++
Sbjct: 1593 PRRSRSGS----SPEVKDK-----PRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK 1643
Query: 624 NPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLED---RLAAAAREKLAQASKESKEKQLQ 680
+P E P+ + A++ + + + R + +++S E K
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 681 AERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDR 740
+ R R A+ +T P SP E+S ++ + P +
Sbjct: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR-RRRSASSPRTKTTSRRGRS 1762
Query: 741 PSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRS--------------HS 786
PS K + R + +++K R R RS S + S + RSRS HS
Sbjct: 1763 PSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
Query: 787 KAKHSLPSAYRTVRRSRSRSRSP---RRRAHS-----PERRREERSVPTAYRVSRS---- 834
++ S+ + RR R RSR+P R+R+ S P +R R+ P +R SRS
Sbjct: 1823 RSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPL 1882
Query: 835 ---------------------PGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSK 873
+R+R+RSR+ +++ RSR+ ++ RS+S +P+
Sbjct: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTT 1942
Query: 874 QAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAI 920
+ R P S S +P +R S+ R+ +++ + +S +
Sbjct: 1943 RRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPV 1989
Score = 74.3 bits (181), Expect = 5e-13
Identities = 62/176 (35%), Positives = 86/176 (48%), Gaps = 12/176 (6%)
Query: 737 PPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAY 796
P R S+S+ PP + + + R R+RSR+ + +SRSR+ + S
Sbjct: 1940 PTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPI-TRRRSRSRTSPVTRRRSRSRT 1998
Query: 797 RTVRRSRSRSRSP---RRRAHS---PERRREERS----VPTAYRVSRSPGASRKRTRSRS 846
V R RSRSR+ RRR+ S P RR RS +P SRSP A R+R+RSR+
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
Query: 847 PHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQ 902
P + K RS +R+ R +S S S R A P A HS S +P + SS+
Sbjct: 2059 PRTARGK-RSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSR 2113
Score = 66.2 bits (160), Expect = 1e-10
Identities = 87/329 (26%), Positives = 129/329 (39%), Gaps = 70/329 (21%)
Query: 637 KKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKN 696
++P +T+ + + +K +RL AA + S + Q R R+A K
Sbjct: 114 QRPAVTETH-QLAELNEKKNERLRAAFGISDSYVDGSSFDPQ---RRAREA-------KQ 162
Query: 697 PLPEAEAGKIEESPFS-VEESSTTPCPLLTGGRPLPTLEVKPPDRPS-SKSKDPPREEEK 754
P PE P+S V ESS++ P P + K DR S+S P RE +K
Sbjct: 163 PAPEPP------KPYSLVRESSSSRSPT-----PKQKKKKKKKDRGRRSESSSPRRERKK 211
Query: 755 EKKKKKHK-----KRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRR-------- 801
KKKKH+ K+ + RS +PK SK + R S++ P + R R
Sbjct: 212 SSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASS 271
Query: 802 ---SRSRSRSPRRRAHSP----------ERRREERSVP-------TAYRVSRSPGASRKR 841
SRSRSRS + H+ RR E P + R S A+++
Sbjct: 272 SDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP 331
Query: 842 TRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQA-----------APRPAAPAAHSAHSA 890
+ +K KK +S +R S P A +P+P A S
Sbjct: 332 SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP- 390
Query: 891 SVSPVESRGSSQERSRGVSQEKEAQISSA 919
V+P +++RS S EK Q SS+
Sbjct: 391 -VNPPSEASPTRDRSPPKSPEKLPQSSSS 418
Score = 65.9 bits (159), Expect = 2e-10
Identities = 73/248 (29%), Positives = 104/248 (41%), Gaps = 27/248 (10%)
Query: 672 KESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLP 731
K S+ + A +R + + PL + SP S S + R
Sbjct: 1862 KRSRSRASPATHRRSRS------RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS-- 1913
Query: 732 TLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHS 791
P R S+S+ PP + + + +R R+RSR+P + +SRSR+ +
Sbjct: 1914 --RASPVSRRRSRSRTPPVTRRRSRSRTPTTRR-RSRSRTPPV-TRRRSRSRTPPVTRRR 1969
Query: 792 LPSAYRTVRRSRSRSR-SPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEK 850
S + R RSRSR SP R RR R+ P R SRS + R RSRS
Sbjct: 1970 SRSRTSPITRRRSRSRTSPVTR-----RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPP 2024
Query: 851 KKKRRSRSRTK--SKARSQSVSP------SKQAAPRPAAPAAHSAHS-ASVSPVESRGSS 901
+RRSRSRT + RS+S SP S+ PR A S ++ + GSS
Sbjct: 2025 AIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS 2084
Query: 902 QERSRGVS 909
+RSR +
Sbjct: 2085 SDRSRSAT 2092
Score = 63.2 bits (152), Expect = 1e-09
Identities = 48/184 (26%), Positives = 81/184 (44%), Gaps = 10/184 (5%)
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSR---SPKYHSSS----KSRSRSHS 786
+V P + + + P E + + KK R R+ S Y S + R+R
Sbjct: 102 DVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAK 161
Query: 787 KAKHSLPSAYRTVRRSRS-RSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSR 845
+ P Y VR S S RS +P+++ ++ R RS ++ R R + +K+ RS
Sbjct: 162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE 221
Query: 846 SPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERS 905
S +K+K R ++K K++ + S+ P P + AH S S S +S+ RS
Sbjct: 222 SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH--RSTSADSASSSDTSRSRS 279
Query: 906 RGVS 909
R +
Sbjct: 280 RSAA 283
Score = 63.2 bits (152), Expect = 1e-09
Identities = 62/224 (27%), Positives = 98/224 (43%), Gaps = 46/224 (20%)
Query: 736 KPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSA 795
+ P R S+S+ P R + + + +R R+RSR+P + + RSRS + A+ S S
Sbjct: 628 RSPVRRRSRSRSPARRSGRSRSRTP-ARRGRSRSRTP----ARRGRSRSRTPARRSGRSR 682
Query: 796 YRT-VRRSRSRSRSPRR------------RAHS------------PERRREERSVPTAYR 830
RT RR RSRSR+PRR R+HS ER+ + R+ R
Sbjct: 683 SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR 742
Query: 831 VSRSPGASRKRTRSR------SPHEKKKKRRSRSRTKSKA----RSQSVSPSKQAAPRPA 880
+ SP + R SR SP K K R S R+ S + + +S +P +++ +
Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS 802
Query: 881 APAAHS------AHSASVSPVESRGSSQERSRGVSQEKEAQISS 918
P A S + S+S P + + + R S ++ S
Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846
Score = 62.8 bits (151), Expect = 1e-09
Identities = 66/247 (26%), Positives = 104/247 (42%), Gaps = 25/247 (10%)
Query: 670 ASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRP 729
+S E K K ++R+ ++ + K+ + + + SP S +S + L+G P
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLS-SPRSKAKSRLSLRRSLSGSSP 784
Query: 730 LPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAK 789
P KS+ PPR + K K R+ R K +S++ S+
Sbjct: 785 C----------PKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
Query: 790 HSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHE 849
HS S + V +S +P R+ + E+SV T R S + +SR+P
Sbjct: 835 HSSSSPHPKV-----KSGTPPRQGSITSPQANEQSV-TPQRRSCFESSPDPELKSRTPSR 888
Query: 850 KKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHS----AHSASVSPVESRGSSQ--- 902
S R KS + SPS+ ++P+P A S +HS S SP SR +S+
Sbjct: 889 HSCSGSSPPRVKSSTPPRQ-SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP 947
Query: 903 ERSRGVS 909
RSR VS
Sbjct: 948 RRSRSVS 954
Score = 62.4 bits (150), Expect = 2e-09
Identities = 79/303 (26%), Positives = 122/303 (40%), Gaps = 27/303 (8%)
Query: 636 EKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQL------QAERKRKAAL 689
E P L +E + + + L+ A EK +S +S + R+R ++
Sbjct: 1364 ETDPSLDMKEQSTRSSGHSSSE-LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSA 1422
Query: 690 FLQTLKNPLPEAEAGKIEE--SPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKD 747
+K+ LP + + SP + S T L+G P + P R S+
Sbjct: 1423 SSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDS 1482
Query: 748 PPREEEKEKKKKKHKKRSRTRS-RSPKYHSS--SKSRSRSHSKAKHSLPSAYRTVRRSRS 804
P E K R R+RS SP+ ++ + R RS S++ + RT RS
Sbjct: 1483 SP-----EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537
Query: 805 RSRSPR----RRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRT 860
RS S + + + SP+ R E S P + +R+P R+R+RS S E K R R
Sbjct: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP--LRQRSRSGSSPEVDSKSRLSPRR 1595
Query: 861 KSKARSQSVSPSKQAAPRPAAPAAHS----AHSASVSPVESRGSSQERSRGVSQEKEAQI 916
S V +AAPR + + S A + P SR S + RG S E +
Sbjct: 1596 SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSST 1655
Query: 917 SSA 919
S+
Sbjct: 1656 ESS 1658
Score = 59.7 bits (143), Expect = 1e-08
Identities = 72/275 (26%), Positives = 113/275 (41%), Gaps = 41/275 (14%)
Query: 631 CVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALF 690
C+ +EE + ++ E +Q ++K+ + + KE Q A +
Sbjct: 70 CLELEE---MMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAE 126
Query: 691 LQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPD--RPSSKSKDP 748
L KN A G I +S V+ SS P + KP R SS S+ P
Sbjct: 127 LNEKKNERLRAAFG-ISDS--YVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSP 183
Query: 749 PREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRS 808
+++K+KKKK +RS S SP+ + R +S K KH RS S S+
Sbjct: 184 TPKQKKKKKKKDRGRRS--ESSSPR-----RERKKSSKKKKH----------RSESESKK 226
Query: 809 PRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQS 868
+ R+ +P+ +R +S RKR+RS +P K + R+ + A S S
Sbjct: 227 RKHRSPTPKSKR------------KSKDKKRKRSRSTTPAPKSR----RAHRSTSADSAS 270
Query: 869 VSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQE 903
S + ++ R AA H+ A SP + G E
Sbjct: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGE 305
Score = 58.2 bits (139), Expect = 4e-08
Identities = 60/266 (22%), Positives = 101/266 (37%), Gaps = 19/266 (7%)
Query: 656 EDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEE 715
+++ + R + +S E K+ ++ + R R + K+ L SP ++
Sbjct: 731 KNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL-SLRRSLSGSSPCPKQK 789
Query: 716 SSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYH 775
S T P +G PP R S S PP+++ K ++ H + S PK
Sbjct: 790 SQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHS----SSSPHPKVK 845
Query: 776 SSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSP 835
S + R S + + + S R S P ++ +P R S P + S P
Sbjct: 846 SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP 905
Query: 836 GASRKRTRSRSPHEK---KKKRRSRSRTKSKA-----------RSQSVSPSKQAAPRPAA 881
S R+ S P K ++RS S + S + RS+SVSP R
Sbjct: 906 RQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLP 965
Query: 882 PAAHSAHSASVSPVESRGSSQERSRG 907
+HS S+ + V+ ++ G
Sbjct: 966 RYSHSGSSSPDTKVKPETPPRQSHSG 991
Score = 53.1 bits (126), Expect = 1e-06
Identities = 98/412 (23%), Positives = 147/412 (35%), Gaps = 104/412 (25%)
Query: 603 DSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRL--A 660
DS D S + Q + A P P +V E + + K+ K+K R +
Sbjct: 143 DSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSES 202
Query: 661 AAAREKLAQASKESKEKQLQAERKRKAALFLQTLK--------------NPLPEAEAGKI 706
++ R + ++SK+ K + +KRK K P P++
Sbjct: 203 SSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHR 262
Query: 707 EESPFSVEESST-----------TPCPLLTGGRPLP----------------TLEVKPPD 739
S S S T T L G P P T + P
Sbjct: 263 STSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPS 322
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHS----------------------- 776
P + +K P E + K KK K +R S SP+ S
Sbjct: 323 SPETATKQPSSPYEDKDKDKKEKSATRP-SPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381
Query: 777 ---------------SSKSRSRSHSKAKHSLPSAY---------RTVRRSRSRSRSPR-- 810
+S +R RS K+ LP + + + SR S SP
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441
Query: 811 RRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRS-RTKSKARSQSV 869
+ A +P RE S PT+ +RS G + KR +S S ++ RSRS T + RS+S
Sbjct: 442 KPAPAPGSHREISSSPTS--KNRSHGRA-KRDKSHSHTPSRRMGRSRSPATAKRGRSRSR 498
Query: 870 SPSKQAAPRPAAPAAHSAHSA-----SVSPVESRGSSQERSR-GVSQEKEAQ 915
+P+K+ R +P + SA S SP + RG S+ R G S+ + Q
Sbjct: 499 TPTKRGHSRSRSPQWRRSRSAQRWGRSRSP-QRRGRSRSPQRPGWSRSRNTQ 549
Score = 51.2 bits (121), Expect = 4e-06
Identities = 68/287 (23%), Positives = 105/287 (36%), Gaps = 25/287 (8%)
Query: 616 SSSSAANTN-----PAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQA 670
++SSA + N PA P V E ++ A A Q ++R ++++ + +
Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542
Query: 671 SKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPL 730
S S + ++ + P+ A K SP TP P
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP--------TPAPKEA----- 2589
Query: 731 PTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKH 790
E +PP+ +K K R S + S S SSS S S S S +
Sbjct: 2590 -VREGRPPEPTPAKRKR--RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 791 SLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEK 850
S PS + ++ + SP++ R R R + R SRS S R SP
Sbjct: 2647 SSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS 2706
Query: 851 KKKRRSRSRTKSKARSQ---SVSPSKQAAPRPAAPAAHSAHSASVSP 894
+ ++S S + R Q S SPS + +P H +S SP
Sbjct: 2707 PRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP-MRHRSSRSP 2752
Score = 48.5 bits (114), Expect = 3e-05
Identities = 74/326 (22%), Positives = 121/326 (37%), Gaps = 48/326 (14%)
Query: 630 PCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAAL 689
PC ++K Q + ++ K + R R + +S K+K R+ ++
Sbjct: 784 PC---PKQKSQTPPRRSRSGSSQPKAKSR--TPPRRSRSSSSPPPKQKSKTPSRQSHSS- 837
Query: 690 FLQTLKNPLPEAEAGKIEE-----SPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSK 744
+P P+ ++G SP + E+S T P P L+ + P R S
Sbjct: 838 -----SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892
Query: 745 SKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPS---AYRTVRR 801
PPR + ++ SR+ S PK + R RSHS + PS + T RR
Sbjct: 893 GSSPPRVKSSTPPRQSP---SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949
Query: 802 SRS-------RSRSPRRRAHS-------------PERRREERSVPTAYRVSRSPGASRKR 841
SRS SR R +HS P R+ S+ +V
Sbjct: 950 SRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSL 1009
Query: 842 TRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSS 901
+ S+SP ++K + S +S S S A + + P S S ++ + +
Sbjct: 1010 SGSKSPCPQEKSK------DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQT 1063
Query: 902 QERSRGVSQEKEAQISSAIVSSVQSK 927
R + E + S + S+QSK
Sbjct: 1064 SPDHRSDTSSPEVRQSHSESPSLQSK 1089
Score = 48.5 bits (114), Expect = 3e-05
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 13/177 (7%)
Query: 731 PTLEVKPPDRPSSKSKDPPRE-EEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAK 789
P + +K P+ K+ RE E K K+RS + S S SSS S S S S +
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631
Query: 790 HSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHE 849
S S+ + S S S SP + +++P + P R+ R P +
Sbjct: 2632 SSSSSSSSSSSSSSSSSPSPAKPG--------PQALPKPASPKKPPPGERRSRSPRKPID 2683
Query: 850 KKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSR 906
+ RS S + + R PS Q +PR ++ S +SR S +R R
Sbjct: 2684 SLRDSRSLSYSPVERRR----PSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
Score = 45.1 bits (105), Expect = 3e-04
Identities = 51/211 (24%), Positives = 78/211 (36%), Gaps = 13/211 (6%)
Query: 709 SPFSVEESSTTPCPLLTGG-RPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHK----- 762
SP + + T P +G P P ++ + P PS P +EK K
Sbjct: 974 SPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSL 1033
Query: 763 ------KRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAH-S 815
K S S SS + + +S + H ++ VR+S S S S + ++ S
Sbjct: 1034 SLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTS 1093
Query: 816 PERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQA 875
P+ R S P SRSP + S SP K +SR +S + S S
Sbjct: 1094 PKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSL 1153
Query: 876 APRPAAPAAHSAHSASVSPVESRGSSQERSR 906
+ A S ++ P E +S R +
Sbjct: 1154 LGQSRLETAESKEKMALPPQEDATASPPRQK 1184
Score = 44.7 bits (104), Expect = 4e-04
Identities = 67/269 (24%), Positives = 108/269 (40%), Gaps = 34/269 (12%)
Query: 695 KNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDR-----PSS------ 743
+ P ++ +G I SP+ ++ T P P L+G + P + K D P S
Sbjct: 982 ETPPRQSHSGSI--SPYPKVKAQTPPGPSLSGSKS-PCPQEKSKDSLVQSCPGSLSLCAG 1038
Query: 744 -KSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRS--RSHSKAKHSLPSAYRTVR 800
KS PP E + K +S+T SP + S + S +SHS++ + + +
Sbjct: 1039 VKSSTPPGESYFGVSSLQLKGQSQT---SPDHRSDTSSPEVRQSHSESPSLQSKSQTSPK 1095
Query: 801 RSRSRSRSP--RRRAHSPERR-REERSVPTAYRVSRSPGASRKRTRSRS---PHEKKKKR 854
RSRS SP + SP R+ R E S + SP SR ++ S S
Sbjct: 1096 GGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLG 1155
Query: 855 RSRSRTKSKARSQSVSPSKQAAPRPAA--------PAAHSAHSASVSPVESRGSSQERSR 906
+SR T ++ P + A P P S+ V R +ERS
Sbjct: 1156 QSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSG 1215
Query: 907 GVSQEKEAQISSAIVSSVQSKITQDLMAK 935
S + + +SA+ +S Q + +++ K
Sbjct: 1216 AGSSPETKEQNSALPTSSQDEELMEVVEK 1244
Score = 43.9 bits (102), Expect = 7e-04
Identities = 47/211 (22%), Positives = 71/211 (33%), Gaps = 40/211 (18%)
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKH--------- 790
+PS+ + P +E + S + S S SSS S S S+
Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL 2576
Query: 791 -----SLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSR 845
P+ VR R +P +R+ RS ++ S S +S + S
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTP--------AKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628
Query: 846 SPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAP------------------AAHSA 887
S S S + S + P QA P+PA+P + +
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688
Query: 888 HSASVSPVESRGSSQERSRGVSQEKEAQISS 918
S S SPVE R S + S Q ++ S
Sbjct: 2689 RSLSYSPVERRRPSPQPSPRDQQSSSSERGS 2719
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 10/165 (6%)
Query: 733 LEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSL 792
L V P P S +PP ++ + RS SSS S S S S + S
Sbjct: 2494 LSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSS 2553
Query: 793 PSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKK 852
S+ + S S + PE + PT +P + + R P K+
Sbjct: 2554 SSSGSSSSDSEGSSLPVQ-----PEVALKRVPSPTP-----APKEAVREGRPPEPTPAKR 2603
Query: 853 KRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVES 897
KRRS S + S + S S S S ++ ++ ++ S+ S+S S S
Sbjct: 2604 KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Score = 34.7 bits (78), Expect = 0.43
Identities = 40/125 (32%), Positives = 53/125 (42%), Gaps = 13/125 (10%)
Query: 788 AKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRV-SRSPGASRKRTRSRS 846
A SL SA S + SPR + ER S P R SR+P ++ ++R S
Sbjct: 2362 APASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTS 2421
Query: 847 PHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHS----ASVSPVESRGSSQ 902
++ S S +A SQS+ P Q PR P+A S S A +PV SQ
Sbjct: 2422 -----ERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV---AGSQ 2473
Query: 903 ERSRG 907
S G
Sbjct: 2474 SLSSG 2478
Score = 33.9 bits (76), Expect = 0.74
Identities = 49/192 (25%), Positives = 67/192 (34%), Gaps = 7/192 (3%)
Query: 724 LTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSR 783
LT R P L P R + + RSRT +P + R+
Sbjct: 2366 LTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAP 2425
Query: 784 SHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERR-REERSVPTAYRVSRSPGASRKRT 842
S S PS + ++ + RSP A S + R ++ P A S S GA T
Sbjct: 2426 SPSSRMGQAPSQ-SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTT 2484
Query: 843 RSRSPHEKKKKRRSRSRTKSK-----ARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVES 897
S H + S A + + PS AA +PA S+ S+S S S
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
Query: 898 RGSSQERSRGVS 909
SS S S
Sbjct: 2545 SSSSSSSSSSSS 2556
Score = 33.9 bits (76), Expect = 0.74
Identities = 42/164 (25%), Positives = 67/164 (40%), Gaps = 16/164 (9%)
Query: 803 RSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASR---KRTRSRSPHEKKKKRRSR-- 857
R+RSR+P A S R ER+ + R+ ++P S + + RSP +SR
Sbjct: 2404 RARSRTPPS-APSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCL 2462
Query: 858 -SRTKSKARSQSVSPSKQAAPRPAA---------PAAHSAHSASVSPVESRGSSQERSRG 907
++T A SQS+S A +A PA HS P S G+ Q +
Sbjct: 2463 IAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALA 2522
Query: 908 VSQEKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS 951
Q + + SS+ SS S + + + + S + + S
Sbjct: 2523 ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS 2566
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 82.8 bits (203), Expect = 1e-15
Identities = 97/374 (25%), Positives = 158/374 (42%), Gaps = 44/374 (11%)
Query: 545 AAEVGARAGSGGKKEASS--SKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDD 602
AA + + SGG+KE +T+PD A+ I+ A + LLP + R+
Sbjct: 1693 AALLSPKESSGGEKEVPPPPKETLPDSGF-SANIEDINEADLVRP--LLPKDMERLT--- 1746
Query: 603 DSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAA 662
EG +S A +P + E+ + + EE + + K++D +
Sbjct: 1747 ---SLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKS 1803
Query: 663 AREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCP 722
+ K +++ EK E+KR ++L ++ ++ E ++ K ES +
Sbjct: 1804 KKNK----NRDKGEK----EKKRDSSLRSRSKRSKSSEHKSRK------RTSESRSR--- 1846
Query: 723 LLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRS---RTRSRSPKYHSSSK 779
R + + S+S+ R + K +RS R RSPK+ S S+
Sbjct: 1847 ----ARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSR 1902
Query: 780 SRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASR 839
R R S ++ + R R+RSR+ S R R+H+P RRR RSV S SP + R
Sbjct: 1903 ERKRKRSSSRDN-----RKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP-SRR 1956
Query: 840 KRT---RSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVE 896
RT RSR+P + + RSRT S+ S+ + R + + S S+SPV
Sbjct: 1957 SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVR 2016
Query: 897 SRGSSQERSRGVSQ 910
R S R S+
Sbjct: 2017 LRRSRTPLRRRFSR 2030
Score = 73.6 bits (179), Expect = 8e-13
Identities = 58/185 (31%), Positives = 85/185 (45%), Gaps = 17/185 (9%)
Query: 736 KPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSA 795
K + S K R +++ K RS+TRSRS SRSRS S+ + S+
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSV--- 1886
Query: 796 YRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRR 855
R RSP+ R+ S ER+R+ S R +R +R RT SR RR
Sbjct: 1887 -----SKEKRKRSPKHRSKSRERKRKRSS----SRDNRKTVRARSRTPSRRSRSHTPSRR 1937
Query: 856 SRSRTKSKARSQSVSPSKQA---APRPAAPAAHSAHSASVSPVESRGS--SQERSRGVSQ 910
RSR+ + RS S+SPS+++ + R P+ S + S SR S RSR S+
Sbjct: 1938 RRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1997
Query: 911 EKEAQ 915
+ ++
Sbjct: 1998 RRRSR 2002
Score = 53.5 bits (127), Expect = 9e-07
Identities = 70/283 (24%), Positives = 119/283 (42%), Gaps = 38/283 (13%)
Query: 584 KAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQ 643
K+K+N KNR K + + D + + S S+ + + E + + +
Sbjct: 1802 KSKKN------KNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT------SESRSRARK 1849
Query: 644 EELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEA 703
++K + + R + R + +++ +S+ ++ ++ KRK + ++ K+ + +
Sbjct: 1850 RSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRS-KSRERKRKR 1908
Query: 704 GKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKK 763
++ +V S TP P + R S S P R + + +
Sbjct: 1909 SSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSR------RSRTPSR 1962
Query: 764 RSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREER 823
RSRT SR RSR+ S+ + RT R RSR+ S RRR+ S RRR
Sbjct: 1963 RSRTPSR----------RSRTPSRRSRTPSRRSRTPSR-RSRTPSRRRRSRSVVRRRSFS 2011
Query: 824 SVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARS 866
P R SR+P +R SRSP RR RSR+ + RS
Sbjct: 2012 ISPVRLRRSRTP---LRRRFSRSP-----IRRKRSRSSERGRS 2046
Score = 41.2 bits (95), Expect = 0.005
Identities = 56/241 (23%), Positives = 102/241 (42%), Gaps = 32/241 (13%)
Query: 705 KIEESPFSVEESSTTPCPLLT-----GGR---PLPTLEVKPPDRPSSKSKDPPREEEKEK 756
K E P V+ES T LL+ GG P P E P S+ +D +
Sbjct: 1677 KDTEEPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRP 1736
Query: 757 KKKKHKKR-----------------SRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
K +R R RS + SS R+ S + + V
Sbjct: 1737 LLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKV 1796
Query: 800 RRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSR 859
+ + +S+ + R + ++ + S+ + + S+S S ++R R+ + + R+ S+
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKS---SEHKSRKRTSESRSRARKRSSK 1853
Query: 860 TKSKARSQSVSPSKQAAPRPAAPA-AHSAHSASVSPVESRGSSQERSRGVSQEKEAQISS 918
+KS RSQ+ S S+ R ++ + + S SVS + + S + RS+ S+E++ + SS
Sbjct: 1854 SKSH-RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSK--SRERKRKRSS 1910
Query: 919 A 919
+
Sbjct: 1911 S 1911
Score = 34.3 bits (77), Expect = 0.57
Identities = 44/159 (27%), Positives = 64/159 (40%), Gaps = 20/159 (12%)
Query: 648 AKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRK--------AALFLQTLKNPLP 699
A +Q + + RE + S E QL E AA ++L N
Sbjct: 2 ATNIEQIFRSFVVSKFREIQQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPN--- 58
Query: 700 EAEAGKIEESPFSVEESSTTPCP-LLTGGRPLPTLEVK--PPDR-PSSKSKDPPREEEKE 755
E KIEE V ++ P L G R + V+ P D P+ KSK + + K+
Sbjct: 59 EEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKK 118
Query: 756 KKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPS 794
KKKKK K++ R S+S+++SH L S
Sbjct: 119 KKKKKEKEKKYKRQ-----PEESESKTKSHDDGNIDLES 152
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 82.8 bits (203), Expect = 1e-15
Identities = 97/374 (25%), Positives = 158/374 (42%), Gaps = 44/374 (11%)
Query: 545 AAEVGARAGSGGKKEASS--SKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDD 602
AA + + SGG+KE +T+PD A+ I+ A + LLP + R+
Sbjct: 1693 AALLSPKESSGGEKEVPPPPKETLPDSGF-SANIEDINEADLVRP--LLPKDMERLT--- 1746
Query: 603 DSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAA 662
EG +S A +P + E+ + + EE + + K++D +
Sbjct: 1747 ---SLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKS 1803
Query: 663 AREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCP 722
+ K +++ EK E+KR ++L ++ ++ E ++ K ES +
Sbjct: 1804 KKNK----NRDKGEK----EKKRDSSLRSRSKRSKSSEHKSRK------RTSESRSR--- 1846
Query: 723 LLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRS---RTRSRSPKYHSSSK 779
R + + S+S+ R + K +RS R RSPK+ S S+
Sbjct: 1847 ----ARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSR 1902
Query: 780 SRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASR 839
R R S ++ + R R+RSR+ S R R+H+P RRR RSV S SP + R
Sbjct: 1903 ERKRKRSSSRDN-----RKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP-SRR 1956
Query: 840 KRT---RSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVE 896
RT RSR+P + + RSRT S+ S+ + R + + S S+SPV
Sbjct: 1957 SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVR 2016
Query: 897 SRGSSQERSRGVSQ 910
R S R S+
Sbjct: 2017 LRRSRTPLRRRFSR 2030
Score = 73.6 bits (179), Expect = 8e-13
Identities = 58/185 (31%), Positives = 85/185 (45%), Gaps = 17/185 (9%)
Query: 736 KPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSA 795
K + S K R +++ K RS+TRSRS SRSRS S+ + S+
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSV--- 1886
Query: 796 YRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRR 855
R RSP+ R+ S ER+R+ S R +R +R RT SR RR
Sbjct: 1887 -----SKEKRKRSPKHRSKSRERKRKRSS----SRDNRKTVRARSRTPSRRSRSHTPSRR 1937
Query: 856 SRSRTKSKARSQSVSPSKQA---APRPAAPAAHSAHSASVSPVESRGS--SQERSRGVSQ 910
RSR+ + RS S+SPS+++ + R P+ S + S SR S RSR S+
Sbjct: 1938 RRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1997
Query: 911 EKEAQ 915
+ ++
Sbjct: 1998 RRRSR 2002
Score = 53.5 bits (127), Expect = 9e-07
Identities = 70/283 (24%), Positives = 119/283 (42%), Gaps = 38/283 (13%)
Query: 584 KAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQ 643
K+K+N KNR K + + D + + S S+ + + E + + +
Sbjct: 1802 KSKKN------KNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT------SESRSRARK 1849
Query: 644 EELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEA 703
++K + + R + R + +++ +S+ ++ ++ KRK + ++ K+ + +
Sbjct: 1850 RSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRS-KSRERKRKR 1908
Query: 704 GKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKK 763
++ +V S TP P + R S S P R + + +
Sbjct: 1909 SSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSR------RSRTPSR 1962
Query: 764 RSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREER 823
RSRT SR RSR+ S+ + RT R RSR+ S RRR+ S RRR
Sbjct: 1963 RSRTPSR----------RSRTPSRRSRTPSRRSRTPSR-RSRTPSRRRRSRSVVRRRSFS 2011
Query: 824 SVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARS 866
P R SR+P +R SRSP RR RSR+ + RS
Sbjct: 2012 ISPVRLRRSRTP---LRRRFSRSP-----IRRKRSRSSERGRS 2046
Score = 41.2 bits (95), Expect = 0.005
Identities = 56/241 (23%), Positives = 102/241 (42%), Gaps = 32/241 (13%)
Query: 705 KIEESPFSVEESSTTPCPLLT-----GGR---PLPTLEVKPPDRPSSKSKDPPREEEKEK 756
K E P V+ES T LL+ GG P P E P S+ +D +
Sbjct: 1677 KDTEEPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRP 1736
Query: 757 KKKKHKKR-----------------SRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
K +R R RS + SS R+ S + + V
Sbjct: 1737 LLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKV 1796
Query: 800 RRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSR 859
+ + +S+ + R + ++ + S+ + + S+S S ++R R+ + + R+ S+
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKS---SEHKSRKRTSESRSRARKRSSK 1853
Query: 860 TKSKARSQSVSPSKQAAPRPAAPA-AHSAHSASVSPVESRGSSQERSRGVSQEKEAQISS 918
+KS RSQ+ S S+ R ++ + + S SVS + + S + RS+ S+E++ + SS
Sbjct: 1854 SKSH-RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSK--SRERKRKRSS 1910
Query: 919 A 919
+
Sbjct: 1911 S 1911
Score = 34.3 bits (77), Expect = 0.57
Identities = 44/159 (27%), Positives = 64/159 (40%), Gaps = 20/159 (12%)
Query: 648 AKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRK--------AALFLQTLKNPLP 699
A +Q + + RE + S E QL E AA ++L N
Sbjct: 2 ATNIEQIFRSFVVSKFREIQQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPN--- 58
Query: 700 EAEAGKIEESPFSVEESSTTPCP-LLTGGRPLPTLEVK--PPDR-PSSKSKDPPREEEKE 755
E KIEE V ++ P L G R + V+ P D P+ KSK + + K+
Sbjct: 59 EEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKK 118
Query: 756 KKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPS 794
KKKKK K++ R S+S+++SH L S
Sbjct: 119 KKKKKEKEKKYKRQ-----PEESESKTKSHDDGNIDLES 152
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 81.3 bits (199), Expect = 4e-15
Identities = 103/448 (22%), Positives = 182/448 (40%), Gaps = 51/448 (11%)
Query: 500 EFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAP-EDAAEVGARAGSGGKK 558
E K++ ++EGG+ +A EE + A E S E +P ++ A+ A A S K+
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 559 EASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLE-KNRVKLDDDSDDDEESKEGQESS 617
EA S V + K+ AKE P E K+ K + S + +S E +S
Sbjct: 537 EAKSPAEVKSPEKAKSP---------AKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587
Query: 618 SSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEK 677
+ +PA A E+ K + +E +AK +++ + A K + +K ++
Sbjct: 588 AKEEAKSPAEAKS---PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644
Query: 678 QLQAERKRKAALFLQTLKNPLPEAEAGKIEE---SPFSVEESSTTPCPLLTGGRPLPTLE 734
+ ++ K K+ PE E K E SP E S P+ E
Sbjct: 645 EAKSPEKAKS-----------PEKEEAKSPEKAKSPVKAEAKSPEKAK-----SPVKA-E 687
Query: 735 VKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSP---------KYHSSSKSRSRSH 785
K P++ S K+ + EK K K + +S +++SP K S K ++S
Sbjct: 688 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747
Query: 786 SKAKHSLPSAYRTVRRSRSRSRSP-RRRAHSPERRREERSVPTAYRVSRSPGASRK--RT 842
KAK P +T+ +++P + A SP + E++ +SP ++ +
Sbjct: 748 EKAKS--PEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE 805
Query: 843 RSRSPHE---KKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRG 899
+++P + KK++ +S + + K + V + A APA S E
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865
Query: 900 SSQERSRGVSQEKEAQISSAIVSSVQSK 927
+ V ++KE + S V++K
Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKESKVEAK 893
Score = 80.1 bits (196), Expect = 9e-15
Identities = 91/437 (20%), Positives = 177/437 (40%), Gaps = 66/437 (15%)
Query: 476 TSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSD 535
T ++ K++++ + ++ + +K+ + +E + Q E A E+
Sbjct: 434 THIKVKSEEKIKVVE---------KSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGK 484
Query: 536 AGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEK 595
E G E+A GG++E S K + +P+ KE P E
Sbjct: 485 EEEGGEEEEA--------EGGEEETKSPPAEEAASPEKEAKSPV------KEEAKSPAEA 530
Query: 596 NRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKL 655
S + EE+K E S +PA EE K + E ++AK
Sbjct: 531 K-------SPEKEEAKSPAEVKSPEKAKSPAK-------EEAKSPPEAKSPEKEEAKSPA 576
Query: 656 EDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEE 715
E + + EK +KE + +A+ KA K+P+ E EA E+ V+E
Sbjct: 577 EVK----SPEKAKSPAKEEAKSPAEAKSPEKA-------KSPVKE-EAKSPAEAKSPVKE 624
Query: 716 SSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSP-KY 774
+ +P EVK P++ S +K+ + EK K +K + +S +++SP K
Sbjct: 625 EAKSPA------------EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672
Query: 775 HSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRS 834
+ S +++S KA+ P ++ + ++S + E + E++ +++
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732
Query: 835 PGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSP 894
P ++ + + +K K +++T ++ +P+K+ A PA A S P
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS----P 788
Query: 895 VESRGSSQERSRGVSQE 911
V+ S E+++ +E
Sbjct: 789 VKEEVKSPEKAKSPLKE 805
Score = 71.6 bits (174), Expect = 3e-12
Identities = 90/387 (23%), Positives = 169/387 (43%), Gaps = 43/387 (11%)
Query: 559 EASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSS 618
E ++ + + +G+ + F PI F++ + +P +K+ + K +E+
Sbjct: 398 EIAAYRKLLEGEECRIGFGPIPFSLP-EGLPKIPSVSTHIKVKSEEKIKVVEKSEKET-- 454
Query: 619 SAANTNPAVAPPCVVVEEK--KPQLTQE--ELEAKQAKQKLEDRLAAAAREKLAQASKES 674
V+VEE+ + Q+T+E E E K+AK++ E+ +E+
Sbjct: 455 -------------VIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEET 501
Query: 675 K----EKQLQAERKRKAALFLQTLKNPLPEAEAGKIEE--SPFSVEESSTTPCPLLTGGR 728
K E+ E++ K+ + + K+P EA++ + EE SP V+ P +
Sbjct: 502 KSPPAEEAASPEKEAKSPV-KEEAKSPA-EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559
Query: 729 PLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKA 788
P E K P++ +KS + EK K K + +S ++SP+ +KS + +K+
Sbjct: 560 SPP--EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE---KAKSPVKEEAKS 614
Query: 789 KHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPH 848
S + +S + +SP + A SP + EE P ++SP ++ ++
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEK-AKSPTK--EEAKSPEK---AKSPEKEEAKSPEKAKS 668
Query: 849 EKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGV 908
K + +S + KS ++++ SP K A P A S A SPV+ S E+++
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEK--AKSPVKEEAKSPEKAK-SPVKEEAKSPEKAKSP 725
Query: 909 SQEKEAQISSAIVSSVQSKITQDLMAK 935
+E EA+ S V+ + AK
Sbjct: 726 VKE-EAKTPEKAKSPVKEEAKSPEKAK 751
Score = 70.5 bits (171), Expect = 7e-12
Identities = 84/395 (21%), Positives = 150/395 (37%), Gaps = 31/395 (7%)
Query: 509 KEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPD 568
KE S V +PE+A + + E S ++ A+ +A S K EA S +
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK- 681
Query: 569 GKLVKASFAPISFAIKAKENDLLPLE---KNRVKLDDDSDDDEESKEGQESSSSAANTNP 625
+P+ K+ E P++ K+ K ++ +S E +S P
Sbjct: 682 --------SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733
Query: 626 AVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKR 685
A V E K P+ + +AK K + A E + A K ++ + + +
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Query: 686 KAALFLQTLKNPL------PEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPD 739
K+ + K+PL PE E K EE V+E P + P E K P
Sbjct: 794 KSP---EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK-PQEVKVKEPPKKAEEEKAPA 849
Query: 740 RPSSKSKDPPREEEKEKK---KKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAY 796
P ++ K ++EE KK K K +++ PK + + K K P
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE 909
Query: 797 RTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRS 856
+ P+ + ++ ++ + + A+ ++ ++ EK KK
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK--EEKAKKPEE 967
Query: 857 RSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSAS 891
+ +T++KA+ + SK+ P+ P A A +S
Sbjct: 968 KPKTEAKAKEDDKTLSKE----PSKPKAEKAEKSS 998
Score = 65.9 bits (159), Expect = 2e-10
Identities = 90/429 (20%), Positives = 167/429 (38%), Gaps = 50/429 (11%)
Query: 508 QKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDA-------AEVGARAGSGGKKEA 560
+KE S V +PE+A + + E S A E +PE A A+ A A S K+EA
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPA-EAKSPEKAKSPVKEEAKSPAEAKSPVKEEA 626
Query: 561 SSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDD----DEESKEGQES 616
S V + K+ P K+ E P EK K + + + +S E +S
Sbjct: 627 KSPAEVKSPEKAKS---PTKEEAKSPEKAKSP-EKEEAKSPEKAKSPVKAEAKSPEKAKS 682
Query: 617 SSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKE 676
A +P A V E K P+ + ++ ++AK + + K + +K +
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK-EEAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 677 KQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVE---ESSTTPCPLLTGGRPLPTL 733
++ ++ K K+ +TL PEA+ EE+ + E + +P
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKE---------- 791
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLP 793
EVK P++ S K+ + EKE KK+ K P+ + ++ + + P
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851
Query: 794 SAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRT---RSRSP--- 847
++ + +P++ A P+ + EE+ P + S ++K + + P
Sbjct: 852 KTEE--KKDSKKEEAPKKEA--PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907
Query: 848 ----------HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVES 897
+ K K ++ K +++ PSK A + AAP E
Sbjct: 908 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE 967
Query: 898 RGSSQERSR 906
+ ++ +++
Sbjct: 968 KPKTEAKAK 976
Score = 62.4 bits (150), Expect = 2e-09
Identities = 66/325 (20%), Positives = 132/325 (40%), Gaps = 30/325 (9%)
Query: 509 KEGGDSMQAVSAP--EEAPTDSAPEKP-----SDAGEDGAPEDAAEVGARAGSGGKKEAS 561
KE S + +P EEA T + P + +PE A + ++ K A
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA-KTPAK 771
Query: 562 SSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAA 621
P K + + +P+ +K+ E PL+++ + + EE K +
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831
Query: 622 NTNPAVAPPCVVVEEKKPQL--TQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQL 679
PP EEK P T+E+ ++K+ + ++ EK A ++ KE ++
Sbjct: 832 EVK-VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV 890
Query: 680 QAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPD 739
+A+++ K P PE EA P VE +P EV +
Sbjct: 891 EAKKEEAE----DKKKVPTPEKEA------PAKVEVKEDA--------KPKEKTEVAKKE 932
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
+K+K+P + EK++ + K +++ P+ ++++++ K PS +
Sbjct: 933 PDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAE 992
Query: 800 RRSRSRSRSPRRRAHSPERRREERS 824
+ +S S + ++ + PE+ E+++
Sbjct: 993 KAEKS-SSTDQKDSKPPEKATEDKA 1016
Score = 51.2 bits (121), Expect = 4e-06
Identities = 69/329 (20%), Positives = 130/329 (39%), Gaps = 29/329 (8%)
Query: 516 QAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKAS 575
+ +PE+A + E S ++ A+ +A S K+EA S + + K
Sbjct: 700 EEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759
Query: 576 FAPISFA-IKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPP---- 630
A AKE P +K K ++ +S E +S P P
Sbjct: 760 DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEE 819
Query: 631 --CVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAA 688
V EE+KPQ E++ K+ +K E+ A A + + K+SK+++ A +K
Sbjct: 820 VKSPVKEEEKPQ----EVKVKEPPKKAEEEKAPATPK--TEEKKDSKKEE--APKKEAPK 871
Query: 689 LFLQTLKNPLPEA-EAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKD 747
++ K P E + K+E E+ P P E + P + K
Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTP-----------EKEAPAKVEVKEDA 920
Query: 748 PPREEEKEKKKKKHKKRSRTRSR-SPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRS 806
P+E+ + KK+ +++ S+ + K ++ + + KAK +T +++
Sbjct: 921 KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP-EEKPKTEAKAKEDD 979
Query: 807 RSPRRRAHSPERRREERSVPTAYRVSRSP 835
++ + P+ + E+S T + S+ P
Sbjct: 980 KTLSKEPSKPKAEKAEKSSSTDQKDSKPP 1008
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 79.7 bits (195), Expect = 1e-14
Identities = 63/188 (33%), Positives = 95/188 (50%), Gaps = 19/188 (10%)
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHS----KAKHSLPSA 795
R S+SK+ R E K+K KKHK + + K HSS K R R +S + +H
Sbjct: 62 RSRSRSKEGRRHESKDKSSKKHK----SEEHNDKEHSSDKGRERLNSSENGEDRHKRKER 117
Query: 796 YRTVRRSRSRSRSPRRRAHSPER-RREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKR 854
+ RS SRSRS RR S R R++ RS + SRS RK++RSRS E+K++
Sbjct: 118 KSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRS-RERKRRI 176
Query: 855 RSRSRTKS------KARSQSVSPSKQAAPRPAAPAAHS---AHSASVSPVESRGSSQERS 905
RSRSR++S ++RS++ S S+ R P S + + S P R ++ +
Sbjct: 177 RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ 236
Query: 906 RGVSQEKE 913
+++ E
Sbjct: 237 EALARRLE 244
Score = 73.2 bits (178), Expect = 1e-12
Identities = 55/184 (29%), Positives = 91/184 (49%), Gaps = 11/184 (5%)
Query: 736 KPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSA 795
K +R +S R + KE+K + + SR+RSR ++ S S+ R +S S+++ S
Sbjct: 97 KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156
Query: 796 YRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRR 855
R+ R +SRSR S ER+R RS + R SR RTRSRS KK+ +
Sbjct: 157 SRSRERKKSRSR-------SRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 209
Query: 856 SRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQ 915
R ++S +R+ S P + R A A A + + + +E+ V ++K+ +
Sbjct: 210 PRRFSRSLSRTPSPPPFR---GRNTAMDAQEALARRLERAKKLQEQREKEM-VEKQKQQE 265
Query: 916 ISSA 919
I++A
Sbjct: 266 IAAA 269
Score = 72.8 bits (177), Expect = 1e-12
Identities = 65/208 (31%), Positives = 94/208 (45%), Gaps = 16/208 (7%)
Query: 739 DRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSH-SKAKHSLPSAYR 797
D+ S K R E + +HK++ R SR + HS S+SR R H S+++ S R
Sbjct: 90 DKEHSSDKGRERLNSSENGEDRHKRKERKSSRG-RSHSRSRSRERRHRSRSRERKKSRSR 148
Query: 798 TVRRSRSRSRSPRR---RAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKR 854
+ R +SRSRS R R+ S ER+R RS SRS R RTRSRS + +
Sbjct: 149 SRERKKSRSRSRERKKSRSRSRERKRRIRSR------SRSRSRHRHRTRSRSRTRSRSRD 202
Query: 855 RSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEA 914
R + K + S+S+S + P A A A +E QE+ EK+
Sbjct: 203 RKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQK 262
Query: 915 QISSAIVSSVQSKITQDLMAKVRAMLAA 942
Q A ++ T + V A+LA+
Sbjct: 263 QQEIAAAAA-----TGGSVLNVAALLAS 285
Score = 72.4 bits (176), Expect = 2e-12
Identities = 60/203 (29%), Positives = 90/203 (44%), Gaps = 29/203 (14%)
Query: 733 LEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRS-------PKYHSSSKSRSRSH 785
+ V P S+ R E+++K ++ R+RSRS K SS K +S H
Sbjct: 29 VSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEH 88
Query: 786 SKAKHSLPSAYRTV--------RRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGA 837
+ +HS + R R +S R R+HS R RE R RS
Sbjct: 89 NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR--------HRSRSR 140
Query: 838 SRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVES 897
RK++RSRS ++KK RSRSR + K+RS+S ++ R + + H + S S
Sbjct: 141 ERKKSRSRS--RERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS----RS 194
Query: 898 RGSSQERSRGVSQEKEAQISSAI 920
R S+ R R EK + S ++
Sbjct: 195 RTRSRSRDRKKRIEKPRRFSRSL 217
Score = 65.1 bits (157), Expect = 3e-10
Identities = 57/199 (28%), Positives = 91/199 (45%), Gaps = 21/199 (10%)
Query: 739 DRPSSKSKDPPREEEKEKKK--------KKHKKRSRTRSRSPKYHSSS---KSRSRSHSK 787
D + + P R+++KE+ + K H RSR+RSR K S + K RSRS SK
Sbjct: 9 DGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSK 68
Query: 788 AKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRR-------EERSVPTAYRVSRSPGASRK 840
S ++ ++ +S + + + R R E+R + SR SR
Sbjct: 69 EGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 128
Query: 841 RTRS---RSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVES 897
R+R RS ++KK RSRSR + K+RS+S K + + S S S
Sbjct: 129 RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 188
Query: 898 RGSSQERSRGVSQEKEAQI 916
R S+ R+R S++++ +I
Sbjct: 189 RTRSRSRTRSRSRDRKKRI 207
Score = 60.8 bits (146), Expect = 6e-09
Identities = 50/179 (27%), Positives = 75/179 (41%), Gaps = 11/179 (6%)
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRS-RSHSKAKHSL 792
E PDR K K+ + K H RSR+RSR K S ++ R RS S++K
Sbjct: 14 EKTSPDR--DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
Query: 793 PSAYRTVRRSRSRSRSPRRRAHSPERRRE-----ERSVPTAYRVSRSPGASRKRTRSRSP 847
+ + +S + HS ++ RE E R R R +RSRS
Sbjct: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS- 130
Query: 848 HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSR 906
++++ RSRSR + K+RS+S K + + S + SR S+ R R
Sbjct: 131 --RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 187
Score = 49.7 bits (117), Expect = 1e-05
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 19/167 (11%)
Query: 771 SPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYR 830
+P+ S + + + S+ S ++ RSRSRSR +R++ + R+ RS R
Sbjct: 12 APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
Query: 831 VSRSPGASRKRTRSRSPHEK-----------------KKKRRSRSRTKSKARSQSVSPSK 873
S S K+ +S ++K + + + + R S+ RS S S S+
Sbjct: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
Query: 874 QAAPRPAAPAAHSAHSASVSPVESRGSSQER--SRGVSQEKEAQISS 918
+ R + + S S +SR S+ER SR S+E++ +I S
Sbjct: 132 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS 178
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 77.4 bits (189), Expect = 6e-14
Identities = 58/162 (35%), Positives = 83/162 (51%), Gaps = 25/162 (15%)
Query: 751 EEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPR 810
EE + K+KKKH++RS SSS S SR++S+ K ++ +SRS SR +
Sbjct: 10 EESRSKRKKKHRRRS---------SSSSSSDSRTYSRKK----GGRKSRSKSRSWSRDLQ 56
Query: 811 RRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVS 870
R+HS +RRR RS S S G+ RKR+RSRS K R RSR+KS+ R
Sbjct: 57 PRSHSYDRRRRHRS-----SSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSR 111
Query: 871 PSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEK 912
P ++ R + ++H SR +ER +G +EK
Sbjct: 112 PRLRSHSRSSERSSHRR-------TRSRSRDRERRKGRDKEK 146
Score = 60.5 bits (145), Expect = 7e-09
Identities = 47/133 (35%), Positives = 64/133 (48%), Gaps = 5/133 (3%)
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
R SS S R ++K +K + +SR+ SR + S S R R H + S + R
Sbjct: 23 RSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRRRHRSSSSSSYGSRRKR 82
Query: 800 RRSRSRSRSPR---RRAHSPERRREERSVPTAYRVSR-SPGASRKRTRSRS-PHEKKKKR 854
RSRSR R +R+ S R R RS P SR S +S +RTRSRS E++K R
Sbjct: 83 SRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERRKGR 142
Query: 855 RSRSRTKSKARSQ 867
R K K + +
Sbjct: 143 DKEKREKEKDKGK 155
Score = 58.9 bits (141), Expect = 2e-08
Identities = 56/199 (28%), Positives = 91/199 (45%), Gaps = 24/199 (12%)
Query: 743 SKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRS 802
S+SK + + + + +R R RS S + S + RSRS S+ + +YR V+RS
Sbjct: 44 SRSKSRSWSRDLQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGR---GKSYR-VQRS 99
Query: 803 RSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKS 862
RS+SR+ R R+ R S +++R +RS R+R + R EK++K + + + K
Sbjct: 100 RSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERRKGRD-KEKREKEKDKGKDKE 158
Query: 863 ------------KARSQSVSPSKQAAPR-----PAAPAAHSAHSASVSPVE--SRGSSQE 903
KA + + P++QA R AA A A A E R ++
Sbjct: 159 LHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKERNEEEAKRRKEED 218
Query: 904 RSRGVSQEKEAQISSAIVS 922
++ V Q K + AI S
Sbjct: 219 QATLVEQVKRVKEIEAIES 237
Score = 41.6 bits (96), Expect = 0.004
Identities = 28/133 (21%), Positives = 56/133 (42%), Gaps = 5/133 (3%)
Query: 742 SSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRR 801
S + + R + K + + RS++R+R + +S SRS ++ H RT R
Sbjct: 78 SRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHR-----RTRSR 132
Query: 802 SRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTK 861
SR R R R E+ +++ + + R + K P ++ K R + +
Sbjct: 133 SRDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLE 192
Query: 862 SKARSQSVSPSKQ 874
+ A++ +K+
Sbjct: 193 AAAKADEALKAKE 205
Score = 40.8 bits (94), Expect = 0.006
Identities = 40/144 (27%), Positives = 61/144 (42%), Gaps = 31/144 (21%)
Query: 800 RRSRSRSRSPRRRAHSPERRREERSVPTAYRV-SRSPGASRKRTRSRS------PH---- 848
RRS R + RRR S + R SR G + R++SRS P
Sbjct: 3 RRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSY 62
Query: 849 ---------------EKKKKRRSRSRTKSKA----RSQSVSPSKQAAPRPAAPAAHSAHS 889
++K+ RSRSR + K+ RS+S S ++++ RP +HS S
Sbjct: 63 DRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRL-RSHSRSS 121
Query: 890 ASVSPVESRGSSQERSRGVSQEKE 913
S +R S++R R ++KE
Sbjct: 122 ERSSHRRTRSRSRDRERRKGRDKE 145
Score = 35.4 bits (80), Expect = 0.25
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 4/107 (3%)
Query: 648 AKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIE 707
A+QAK +L+ L AAA+ A +KE E++ + ++ A ++ +K + E EA IE
Sbjct: 180 AEQAKARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQATLVEQVKR-VKEIEA--IE 236
Query: 708 ESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEK 754
F V+++ + + P + P+S DPP E++
Sbjct: 237 SDSF-VQQTFRSSKEVKKSVEPSEVKQATSTSGPASAVADPPSTEKE 282
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 77.0 bits (188), Expect = 8e-14
Identities = 64/175 (36%), Positives = 90/175 (51%), Gaps = 22/175 (12%)
Query: 755 EKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAH 814
E K + +RS + SRS S+SR RS S+++ S S R++ +SRSRSRS R +
Sbjct: 180 EDKPRTSHRRSYSGSRS-----RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRS-RSKGR 233
Query: 815 SPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKR-RSRSRT---------KSKA 864
S R + +S + +S S +RSRS E +K R RSRSR+ KSK+
Sbjct: 234 SRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293
Query: 865 RSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSA 919
RS+S S S P P + A SVSP R +S+ RSR S+ + SS+
Sbjct: 294 RSRSQSRSNSPLPVPPSKAR------SVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
Score = 68.6 bits (166), Expect = 3e-11
Identities = 82/276 (29%), Positives = 121/276 (43%), Gaps = 46/276 (16%)
Query: 640 QLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLP 699
+L E L ++ + Q L+D + A A A KE + + R +K L
Sbjct: 111 RLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRS------YSDMKRALD 164
Query: 700 EAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKK 759
+ + +I + E P + R + R S+S+ R + + +
Sbjct: 165 KLDGTEINGRNIRLIEDK----PRTSHRRSYSGSRSRSRSRRRSRSRS--RRSSRSRSRS 218
Query: 760 KHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRS-PR--RRAHSP 816
K RSR+RSR SK RSRS SK R+SRS+S+S P+ R +HS
Sbjct: 219 ISKSRSRSRSR-------SKGRSRSRSKG-----------RKSRSKSKSKPKSDRGSHSH 260
Query: 817 ERRREERSVPTAYRVSRSPGASRKRTRSRSPHEK-KKKRRSRSRTKSKARSQSVSPSKQA 875
R R + Y SRS R+RSRSP E K +S+SR++S++RS S P +
Sbjct: 261 SRSRSK----DEYEKSRS------RSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPS 310
Query: 876 APRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQE 911
R +P A S S S SR S+ RSR S++
Sbjct: 311 KARSVSPPPKRATSRSRS--RSRSKSRSRSRSSSRD 344
Score = 48.5 bits (114), Expect = 3e-05
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 15/121 (12%)
Query: 827 TAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSK------------- 873
T++R S S SR R+R RS ++ RSRSR+ SK+RS+S S SK
Sbjct: 185 TSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSR 244
Query: 874 -QAAPRPAAPAAHSAHSASVSPVE-SRGSSQERSRGVSQEKEAQISSAIVSSVQSKITQD 931
++ +P + +HS S S E + S+ RSR + + I S S QS+
Sbjct: 245 SKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSP 304
Query: 932 L 932
L
Sbjct: 305 L 305
Score = 37.0 bits (84), Expect = 0.088
Identities = 36/130 (27%), Positives = 55/130 (42%), Gaps = 5/130 (3%)
Query: 820 REERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSK---QAA 876
R R + R S S R+RSRS + + R SR++S++ S+S S S+ +
Sbjct: 174 RNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR 233
Query: 877 PRPAAPAAHSAHSASVSPVESRGS-SQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAK 935
R + S + P RGS S RSR E E S + S + D+ +K
Sbjct: 234 SRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRS-KDEYEKSRSRSRSRSPKENGKGDIKSK 292
Query: 936 VRAMLAASKN 945
R+ + N
Sbjct: 293 SRSRSQSRSN 302
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 76.6 bits (187), Expect = 1e-13
Identities = 52/174 (29%), Positives = 86/174 (49%), Gaps = 6/174 (3%)
Query: 743 SKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRS 802
S + +P ++EEK + + + R R+ S H S+SRSR S +K ++ RR
Sbjct: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR 293
Query: 803 RSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRT-RSRSPHEKKKKRRSRSRTK 861
RS SR RR+ S + R+++ + S++P S RSRS ++++RRSRS T+
Sbjct: 294 RSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTR 353
Query: 862 SKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQ 915
S + +S K+ R +P H E S ER R S++K+++
Sbjct: 354 SPKKPRS---PKRKLSRSPSPRRHKKEKKKDKDKER--SRDERERSTSKKKKSK 402
Score = 65.9 bits (159), Expect = 2e-10
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 4/130 (3%)
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRS----HSKAKHSLPSA 795
R S+ + + + + K ++RS +R R + S+SK+R + K + P +
Sbjct: 270 RSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKS 329
Query: 796 YRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRR 855
Y T RRSRS SR RRR R ++ ++SRSP R + + +K++ R
Sbjct: 330 YSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD 389
Query: 856 SRSRTKSKAR 865
R R+ SK +
Sbjct: 390 ERERSTSKKK 399
Score = 56.6 bits (135), Expect = 1e-07
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 16/144 (11%)
Query: 736 KPPDRPSSKSKDPPREEEKEKK----KKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHS 791
K P R S S++ R K KK+ K++ R+++ Y ++ +SRS S + +
Sbjct: 288 KSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR-- 345
Query: 792 LPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKK 851
RRSRS +RSP ++ SP+R+ P ++ + ++R+R
Sbjct: 346 --------RRSRSGTRSP-KKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS 396
Query: 852 KKRRSRSRTKSKAR-SQSVSPSKQ 874
KK++S+ + K + R S+S KQ
Sbjct: 397 KKKKSKDKEKDRERKSESDKDVKQ 420
Score = 46.2 bits (108), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 12/149 (8%)
Query: 732 TLEVKPPDRPSSKSKDPP-------REEEKEKKKKKHKKRSRTRS----RSPKYHSSSKS 780
T + K D+ +SK PP R +++++ + RS TRS RSPK S
Sbjct: 310 TRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSP 369
Query: 781 RSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRK 840
R H K K R+ R R RS S ++++ E+ RE +S + +
Sbjct: 370 SPRRHKKEKKKDKDKERS-RDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE 428
Query: 841 RTRSRSPHEKKKKRRSRSRTKSKARSQSV 869
S EKK++++ K + SV
Sbjct: 429 EQGYDSEKEKKEEKKPIETGSPKTKECSV 457
Score = 43.9 bits (102), Expect = 7e-04
Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 8/144 (5%)
Query: 780 SRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASR 839
S S + + A + VR ++S + E+RR RS + R R+P +SR
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRR-RRTPSSSR 265
Query: 840 -KRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPA-----AHSAHSASVS 893
+R+RSRS K RSR R+KS R +S S + R + S +
Sbjct: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKT 325
Query: 894 PVESRGSSQERSRGVSQEKEAQIS 917
P +S S+ RSR S+E+ + S
Sbjct: 326 PPKSY-STARRSRSASRERRRRRS 348
Score = 34.7 bits (78), Expect = 0.43
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 8/123 (6%)
Query: 732 TLEVKPPDRPSSK-SKDP-PREEEKEKKKKKHKKRSRTRSRSPKYHSSS-KSRSRSHSKA 788
T K P P K S+ P PR +KEKKK K + RSR + S+S K +S+ K
Sbjct: 352 TRSPKKPRSPKRKLSRSPSPRRHKKEKKKDK----DKERSRDERERSTSKKKKSKDKEKD 407
Query: 789 KHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPH 848
+ + + V++ +R + + E+ ++E P ++ S ++ S
Sbjct: 408 RERKSESDKDVKQV-TRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLR 466
Query: 849 EKK 851
E K
Sbjct: 467 ESK 469
Score = 30.4 bits (67), Expect = 8.2
Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 10/97 (10%)
Query: 637 KKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKN 696
+ P + + E K+ K K R RE+ K+SK+K+ ERK ++ ++ +
Sbjct: 367 RSPSPRRHKKEKKKDKDKERSR---DERERSTSKKKKSKDKEKDRERKSESDKDVKQVTR 423
Query: 697 PLPEAEAG-------KIEESPFSVEESSTTPCPLLTG 726
E E G K E+ P T C + G
Sbjct: 424 DYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKG 460
>gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo
sapiens]
Length = 793
Score = 75.5 bits (184), Expect = 2e-13
Identities = 46/117 (39%), Positives = 60/117 (51%), Gaps = 9/117 (7%)
Query: 408 VTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYV 467
V PPPP T PT E SS S + PV II PPP+V+ ++DK A +V
Sbjct: 6 VQAVPPPPPVPTEPKQPTEEEASSKEDSAPSK-----PVVGIIYPPPEVRNIVDKTASFV 60
Query: 468 ARNGLKFETSVRAK--NDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPE 522
ARNG +FE +R N+ +F FL P Y+AYY K F KEG + + P+
Sbjct: 61 ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEF--KEGKAQEPSAAIPK 115
Score = 53.5 bits (127), Expect = 9e-07
Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 18/106 (16%)
Query: 159 DPSEPTEEEEPSKQREKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASF 218
+P +PTEEE SK E+ P +G+ P PP ++ I+++TASF
Sbjct: 18 EPKQPTEEEASSK-----------EDSAPSKPVVGIIYP-----PP--EVRNIVDKTASF 59
Query: 219 VCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGR 264
V R G +FE ++ + N +F+FL + + YY+ KEG+
Sbjct: 60 VARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK 105
Score = 49.3 bits (116), Expect = 2e-05
Identities = 108/497 (21%), Positives = 178/497 (35%), Gaps = 56/497 (11%)
Query: 160 PSEPTEEEEPSKQR--EKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHA--IIERT 215
P ++++ ++Q+ +K +A+ ++E P P +D PP+ +++ T
Sbjct: 114 PKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIAD---PPSISAFDLDVVKLT 170
Query: 216 ASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYY-KFIQKAMKEGRYTVLAENKSD 274
A FV R G QF L K+ RN QFDFLR H L Y+ K ++ +YT +
Sbjct: 171 AQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVE------QYTKILIPPKG 224
Query: 275 EKKKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLEELMKPLKVVDPD---HPLAALVR 331
K ++N + ++ + + F ++ + EE + +V H +
Sbjct: 225 LFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVET 284
Query: 332 -----KAQADSSTPTPHNADGAPVQ-PSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPP 385
Q + PT GA + + E +S M D PP
Sbjct: 285 VDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPS 344
Query: 386 GIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAP 445
+D T + G S+ PPPP TP+PPP A P
Sbjct: 345 QLDQDTQVQDMDEG---SDDEEEGQKVPPPP-ETPMPPPLPPTPDQVIVRKDYDPKASKP 400
Query: 446 VAAIIPPPPDVQPVIDKLAEYVAR--NGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKK 503
+PP P EY+ G K S + + R L P + E +
Sbjct: 401 ----LPPAPAPD-------EYLVSPITGEKIPAS-KMQEHMRIGLLDP-----RWLEQRD 443
Query: 504 QFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSG--GKKEAS 561
+ +K+ D + A E+ E+ +D G E A +G + G K E
Sbjct: 444 RSIREKQSDDEVYAPGLDIESSLKQLAERRTDI--FGVEETA--IGKKIGEEEIQKPEEK 499
Query: 562 SSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEG----QESS 617
+ G + + A + ++ + + K V DD + SK Q
Sbjct: 500 VTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPP 559
Query: 618 SSAANTNPAVAPPCVVV 634
S+A P+ APP V
Sbjct: 560 PSSATNIPSSAPPITSV 576
Score = 39.3 bits (90), Expect = 0.018
Identities = 43/165 (26%), Positives = 58/165 (35%), Gaps = 34/165 (20%)
Query: 337 SSTPTPHNADGAPVQPSQVEYTADSTVAAM----YYSYYMLPDGTYCLAPPPPGIDVTTY 392
SS P + P P V T S V M S LP G+ +AP PP
Sbjct: 568 SSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSV-IAPMPP------- 619
Query: 393 YSTLPAGVTVSNSPGVTTTAPPP---PGTTPLPPPTTAETSSGATSTTTTTSALAPVAAI 449
+ ++P + PP P P PPP T+ A AP+ +
Sbjct: 620 ---------IIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPV 670
Query: 450 IPPPP-DVQPVIDKL---------AEYVARNGLKFETSVRAKNDQ 484
PPPP + +P KL E++ RN V+ N Q
Sbjct: 671 HPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQ 715
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 75.5 bits (184), Expect = 2e-13
Identities = 55/140 (39%), Positives = 77/140 (55%), Gaps = 11/140 (7%)
Query: 752 EEKEKKKKKHKKRSRTRSRSPKYH--------SSSKSRSRSHSKAKHSLPSAYRTVRRSR 803
EE++ KKK +RSR++SRS SSS+SRSRS S++ S S R+ R R
Sbjct: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
Query: 804 SRSRSPRRRAHSPERRREERSVPTAY-RVSRSPGASRKRTRSRSPHE-KKKKRRSRSRTK 861
SRSR + R+ S R +Y S SP +RKR+RSRS +KKRR+RSR+
Sbjct: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP 308
Query: 862 SKARSQSVSPSKQAAPRPAA 881
+ R +S S S + R ++
Sbjct: 309 ER-RHRSSSGSSHSGSRSSS 327
Score = 60.5 bits (145), Expect = 7e-09
Identities = 57/175 (32%), Positives = 84/175 (48%), Gaps = 21/175 (12%)
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKH--- 790
E + D SK K E+E + K+ + S K S RSRS S++ H
Sbjct: 156 EEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNK--KKSNRRSRSKSRSSHSRS 213
Query: 791 ----SLPSAYRTVRRSRSRSRS---PRRRAHSPERRR----EERSVPTAYRVSRSPGASR 839
S PS+ R+ RSRSRS S R R+ S ER R + RS ++R S SP
Sbjct: 214 SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRS 273
Query: 840 KRTRSRSPHEKKKKRRSRSRT---KSKARSQSVSPSKQAAPRPAAPAAHSAHSAS 891
+ S SP +K+ RSRS + + K R++S SP ++ R ++ ++HS +S
Sbjct: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERR--HRSSSGSSHSGSRSS 326
Score = 55.8 bits (133), Expect = 2e-07
Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 22/168 (13%)
Query: 751 EEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPR 810
E+E K K + + KY+ + S+ K + RRSRS+SRS
Sbjct: 160 EDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSN---------RRSRSKSRSSH 210
Query: 811 RRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVS 870
R+ S S P++ R SR R+RSRS + + RS SR +S++R
Sbjct: 211 SRSSS------RSSSPSSSR-------SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSR 257
Query: 871 PSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISS 918
S ++ ++P S S+S SP +R S+ RS K+ + S
Sbjct: 258 SSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS 305
Score = 55.8 bits (133), Expect = 2e-07
Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 738 PDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYR 797
P S+S+ R + + + R R+RSR K SSS+S S S K S S+
Sbjct: 220 PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS 279
Query: 798 TVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSR 857
+ R+R RSRS R S S ++RTRSRSP + +
Sbjct: 280 SPERNRKRSRS---------------------RSSSSGDRKKRRTRSRSPERRHRSSSGS 318
Query: 858 SRTKSKARSQ 867
S + S++ S+
Sbjct: 319 SHSGSRSSSK 328
Score = 38.9 bits (89), Expect = 0.023
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 848 HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHS-AHSASVSPVESRGSSQERSR 906
++KK RRSRS+++S S S S S+ ++P + + S + S+S S SR SS+ERSR
Sbjct: 194 NKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSR 250
Query: 907 GVSQEKEAQISSAIVSSVQSK 927
+ + S SS K
Sbjct: 251 SRGSKSRSSSRSHRGSSSPRK 271
Score = 36.6 bits (83), Expect = 0.11
Identities = 52/270 (19%), Positives = 91/270 (33%), Gaps = 72/270 (26%)
Query: 555 GGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQ 614
G KK+ K V ++K S + E++ L K ++ D+D DD + SK
Sbjct: 128 GRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDE--DLSKYKLDEDEDEDDADLSKYNL 185
Query: 615 ESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKES 674
++S +E+ K++ ++ + ++ +++S S
Sbjct: 186 DASE------------------------EEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPS 221
Query: 675 KEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLE 734
+ R R ++
Sbjct: 222 SSRSRSRSRSRSSS---------------------------------------------S 236
Query: 735 VKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPS 794
+ R SS+ + R + + H+ S R RS SSS R+R S+++ S S
Sbjct: 237 SQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-SS 295
Query: 795 AYRTVRRSRSRSRSPRRRAHSPERRREERS 824
R RR+RSRS R R+ S RS
Sbjct: 296 GDRKKRRTRSRSPERRHRSSSGSSHSGSRS 325
>gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Homo
sapiens]
Length = 728
Score = 74.7 bits (182), Expect = 4e-13
Identities = 45/106 (42%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 408 VTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYV 467
V PPPP T PT E SS S + PV II PPP+V+ ++DK A +V
Sbjct: 6 VQAVPPPPPVPTEPKQPTEEEASSKEDSAPSK-----PVVGIIYPPPEVRNIVDKTASFV 60
Query: 468 ARNGLKFETSVRAK--NDQRFEFLQPWHQYNAYYEFKKQFFLQKEG 511
ARNG +FE +R N+ +F FL P Y+AYY K F KEG
Sbjct: 61 ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEF--KEG 104
Score = 56.2 bits (134), Expect = 1e-07
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 18/113 (15%)
Query: 159 DPSEPTEEEEPSKQREKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASF 218
+P +PTEEE SK E+ P +G+ P PP ++ I+++TASF
Sbjct: 18 EPKQPTEEEASSK-----------EDSAPSKPVVGIIYP-----PP--EVRNIVDKTASF 59
Query: 219 VCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAEN 271
V R G +FE ++ + N +F+FL + + YY+ KEG+ +A N
Sbjct: 60 VARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQFVARN 112
Score = 39.3 bits (90), Expect = 0.018
Identities = 43/165 (26%), Positives = 58/165 (35%), Gaps = 34/165 (20%)
Query: 337 SSTPTPHNADGAPVQPSQVEYTADSTVAAM----YYSYYMLPDGTYCLAPPPPGIDVTTY 392
SS P + P P V T S V M S LP G+ +AP PP
Sbjct: 503 SSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSV-IAPMPP------- 554
Query: 393 YSTLPAGVTVSNSPGVTTTAPPP---PGTTPLPPPTTAETSSGATSTTTTTSALAPVAAI 449
+ ++P + PP P P PPP T+ A AP+ +
Sbjct: 555 ---------IIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPV 605
Query: 450 IPPPP-DVQPVIDKL---------AEYVARNGLKFETSVRAKNDQ 484
PPPP + +P KL E++ RN V+ N Q
Sbjct: 606 HPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQ 650
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 73.9 bits (180), Expect = 6e-13
Identities = 58/197 (29%), Positives = 86/197 (43%), Gaps = 6/197 (3%)
Query: 735 VKPPDRPS-SKSKDPPREEEKEKKKK---KHKKRSRTRSRSPKYHSSSKSRSRSHSKAKH 790
VK ++ S SK KD R KEK K+ K + ++S+ + S+SR +K KH
Sbjct: 497 VKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKH 556
Query: 791 SLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSP--H 848
S S R RSR RSR R R H +R R + + R G SR R R P
Sbjct: 557 SYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRS 616
Query: 849 EKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGV 908
K +RR R ++S R +S S +K + ++H ++ S S
Sbjct: 617 RSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNN 676
Query: 909 SQEKEAQISSAIVSSVQ 925
S+EK+A + S ++
Sbjct: 677 SREKKADRDQSPFSKIK 693
Score = 72.4 bits (176), Expect = 2e-12
Identities = 90/358 (25%), Positives = 149/358 (41%), Gaps = 50/358 (13%)
Query: 586 KENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEE 645
KEN P+ K+ D + E E + K+ + +
Sbjct: 392 KENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKS---------NSKERDIRRNS 442
Query: 646 LEAKQAKQKLEDRLAAAAREKLAQASK----ESKEKQLQAERKRKAALFL--QTLKNPLP 699
+ + K K++ R + +R K + SK +SK + + +R R + + +K
Sbjct: 443 EKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEK 502
Query: 700 EAEA-GKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKK- 757
++++ GK +E S E+S LE K + SKSK+ R + +
Sbjct: 503 QSDSKGKDQERSRSKEKSKQ--------------LESKSNEHDHSKSKEKDRRAQSRSRE 548
Query: 758 ----KKKH------KKRSRTRSRSPKYHSSSKSRSRSHSKAKHSL-PSAYRTVRRSRSRS 806
K KH ++RSR+R RS + S + R RS SK H YR RSRSR
Sbjct: 549 CDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRE 608
Query: 807 -RSPRRRAHSPERRREERSVPTAYR-VSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKA 864
R+P R+ S +RRR R ++ R S+S + R + +K+ S R SK+
Sbjct: 609 RRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKS 668
Query: 865 RSQSVSPS--KQAAPRPAAPAAHSAHSASVSPVES---RGSSQERSRGVSQEKEAQIS 917
R + S + ++ A R +P + S+ + ++S + E+ R S EKE Q S
Sbjct: 669 RDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRS-SVEKENQKS 725
Score = 67.8 bits (164), Expect = 5e-11
Identities = 86/422 (20%), Positives = 167/422 (39%), Gaps = 49/422 (11%)
Query: 507 LQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTV 566
++KE ++ S+ + +DS S + D + ++A K +S K
Sbjct: 183 VKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHK 242
Query: 567 PDGKLVKASFAPISFAIKAKE-----------NDLLPLEKNRVKLDDDSDDDEESKEGQE 615
+ K K S S +A+ ++ P+ +NR + +E +
Sbjct: 243 KEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNR 302
Query: 616 SSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQ-KLEDRLAAAAREKLAQASKES 674
NP + P + +++ + ++ + R + R + ++
Sbjct: 303 ERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHW 362
Query: 675 KEKQLQAERKRKAA--LFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPT 732
+++ +A+R R ++ +++ K+ L E + + SP V+E T
Sbjct: 363 RQEMQRAQRMRVSSGERWIKGDKSELNEIKEN--QRSPVRVKERKITD------------ 408
Query: 733 LEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTR------SRSPKYHSSSKSRSRSHS 786
+ S+ P R+ EKEKK K HK S+ R + KY + K R++S S
Sbjct: 409 --------HRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKS 460
Query: 787 KAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRS 846
++K S ++ R +R+ +R S + R+ +V + S S G ++R+RS+
Sbjct: 461 RSKSKEKS--KSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK- 517
Query: 847 PHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSR 906
EK K+ S+S ++S+ Q+ R HS + S R S++RSR
Sbjct: 518 --EKSKQLESKSNEHDHSKSKEKDRRAQSRSR-ECDITKGKHSYN-SRTRERSRSRDRSR 573
Query: 907 GV 908
V
Sbjct: 574 RV 575
Score = 67.0 bits (162), Expect = 8e-11
Identities = 81/377 (21%), Positives = 139/377 (36%), Gaps = 103/377 (27%)
Query: 608 EESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKL 667
EE K + SSSS+++++ + +Q ++ ++ E++ ++
Sbjct: 186 EEKKRHKSSSSSSSSSS----------DSDSSSDSQSSSDSSDSESATEEKSKKRKKKHR 235
Query: 668 AQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGG 727
+ K KEK+ + + K+ A+ E+EA +E P S P
Sbjct: 236 KNSRKHKKEKKKRKKSKKSAS----------SESEAENLEAQPQSTVRPEEIP------- 278
Query: 728 RPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTR--SRSPKYHSSSKSRSRSH 785
P+P + K PP+ +EKE+K ++ ++ + P + +RS
Sbjct: 279 -PIP-------ENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSG 330
Query: 786 SKAKHSLPSAYRTVRRSRSRSR----------------SPRRRAHSPER----------- 818
K K P YRT RSRSR R + R R S ER
Sbjct: 331 RKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNE 390
Query: 819 ---------RREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRS-----------RS 858
R +ER + VS SP ++ + H+ K R ++
Sbjct: 391 IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKN 450
Query: 859 RTKSKARSQSVSPSKQAAPRPAAPAAHSAH-----------------SASVSPVESRGSS 901
+ K +A+S+S S SK+ + + H+ + +S+G
Sbjct: 451 KVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKD 510
Query: 902 QERSRGVSQEKEAQISS 918
QERSR S+EK Q+ S
Sbjct: 511 QERSR--SKEKSKQLES 525
Score = 47.0 bits (110), Expect = 8e-05
Identities = 36/173 (20%), Positives = 73/173 (42%), Gaps = 8/173 (4%)
Query: 749 PREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRS 808
P+ + K+++KK+HK S + S S SSS S+S S S S R+ + R S
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 809 PRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRS----PHEKKKKRRSRSRTKSKA 864
+ + +R++ ++S + + R P + R+S + K
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKE 298
Query: 865 R-SQSVSPSKQAAPRPAAPAAHSAH---SASVSPVESRGSSQERSRGVSQEKE 913
R ++ ++ P + PA++ + S ++ RG + R+ S+ ++
Sbjct: 299 RKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRD 351
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 73.9 bits (180), Expect = 6e-13
Identities = 70/275 (25%), Positives = 114/275 (41%), Gaps = 33/275 (12%)
Query: 642 TQEELEAKQAKQKLEDRLAAAAREKLAQASKE-SKEKQLQAERKRKAALFLQTLKNPLPE 700
T+E+++ K+ + K +DR REK + KE K K ER++ + K E
Sbjct: 380 TREKIKEKE-RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR----EKDKEKDRE 434
Query: 701 AEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPRE-EEKEKKKK 759
E K E E+ K D+ + KD +E +EK KK K
Sbjct: 435 REREKEHEKDRDKEKE-------------------KEQDKEKEREKDRSKEIDEKRKKDK 475
Query: 760 KHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERR 819
K + R+ + S + SSS+ R R S++ P +T++R SRS SPR R ++R
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 535
Query: 820 REERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRP 879
+ER + R + RK + R EK +K + + K + S SK+ +
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK- 594
Query: 880 AAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEA 914
A + ++ G+ Q +S + EA
Sbjct: 595 ------DAPRTEENKIQHNGNCQLNEENLSTKTEA 623
Score = 59.7 bits (143), Expect = 1e-08
Identities = 55/198 (27%), Positives = 84/198 (42%), Gaps = 36/198 (18%)
Query: 723 LLTGGRPLPTLE-----VKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSS 777
++ G RPL VKPP+ + E K ++ + + S K +
Sbjct: 244 VMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNER 303
Query: 778 SKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGA 837
RSRSH+++K RS S+S S R+R+ S R R +RS
Sbjct: 304 KGGRSRSHTRSK----------SRSSSKSHSRRKRSQSKHRSRSH---------NRSRSR 344
Query: 838 SRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVES 897
+ R RS+SPH K+RS+SR + K+RS+S S K+ R V+
Sbjct: 345 QKDRRRSKSPH----KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER--------VKE 392
Query: 898 RGSSQERSRGVSQEKEAQ 915
+ +ER R +EKE +
Sbjct: 393 KDREKEREREKEREKEKE 410
Score = 58.5 bits (140), Expect = 3e-08
Identities = 56/265 (21%), Positives = 102/265 (38%), Gaps = 11/265 (4%)
Query: 674 SKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTL 733
+KE + +R R+A F+ P E+GK E S T +
Sbjct: 272 AKELEEVMKRVREAQSFISAAIEP----ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRK 327
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKHKKRS----RTRSRSPKYHSSSKSRSRSHSKAK 789
+ R S ++ R++++ + K HKKRS R +SRS + + +R K K
Sbjct: 328 RSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK 387
Query: 790 HSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHE 849
+ R R R + R + + R +ER + R++ + +
Sbjct: 388 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 447
Query: 850 KKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAH---SAHSASVSPVESRGSSQERSR 906
+K+K + + + + K RS+ + ++ + P S S S S R S+ SR
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 507
Query: 907 GVSQEKEAQISSAIVSSVQSKITQD 931
K + S+ S +S+ +D
Sbjct: 508 SPRTSKTIKRKSSRSPSPRSRNKKD 532
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 73.9 bits (180), Expect = 6e-13
Identities = 70/275 (25%), Positives = 114/275 (41%), Gaps = 33/275 (12%)
Query: 642 TQEELEAKQAKQKLEDRLAAAAREKLAQASKE-SKEKQLQAERKRKAALFLQTLKNPLPE 700
T+E+++ K+ + K +DR REK + KE K K ER++ + K E
Sbjct: 264 TREKIKEKE-RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR----EKDKEKDRE 318
Query: 701 AEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPRE-EEKEKKKK 759
E K E E+ K D+ + KD +E +EK KK K
Sbjct: 319 REREKEHEKDRDKEKE-------------------KEQDKEKEREKDRSKEIDEKRKKDK 359
Query: 760 KHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERR 819
K + R+ + S + SSS+ R R S++ P +T++R SRS SPR R ++R
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 419
Query: 820 REERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRP 879
+ER + R + RK + R EK +K + + K + S SK+ +
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK- 478
Query: 880 AAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEA 914
A + ++ G+ Q +S + EA
Sbjct: 479 ------DAPRTEENKIQHNGNCQLNEENLSTKTEA 507
Score = 59.7 bits (143), Expect = 1e-08
Identities = 55/198 (27%), Positives = 84/198 (42%), Gaps = 36/198 (18%)
Query: 723 LLTGGRPLPTLE-----VKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSS 777
++ G RPL VKPP+ + E K ++ + + S K +
Sbjct: 128 VMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNER 187
Query: 778 SKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGA 837
RSRSH+++K RS S+S S R+R+ S R R +RS
Sbjct: 188 KGGRSRSHTRSK----------SRSSSKSHSRRKRSQSKHRSRSH---------NRSRSR 228
Query: 838 SRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVES 897
+ R RS+SPH K+RS+SR + K+RS+S S K+ R V+
Sbjct: 229 QKDRRRSKSPH----KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER--------VKE 276
Query: 898 RGSSQERSRGVSQEKEAQ 915
+ +ER R +EKE +
Sbjct: 277 KDREKEREREKEREKEKE 294
Score = 58.5 bits (140), Expect = 3e-08
Identities = 56/265 (21%), Positives = 102/265 (38%), Gaps = 11/265 (4%)
Query: 674 SKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTL 733
+KE + +R R+A F+ P E+GK E S T +
Sbjct: 156 AKELEEVMKRVREAQSFISAAIEP----ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRK 211
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKHKKRS----RTRSRSPKYHSSSKSRSRSHSKAK 789
+ R S ++ R++++ + K HKKRS R +SRS + + +R K K
Sbjct: 212 RSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK 271
Query: 790 HSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHE 849
+ R R R + R + + R +ER + R++ + +
Sbjct: 272 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 331
Query: 850 KKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAH---SAHSASVSPVESRGSSQERSR 906
+K+K + + + + K RS+ + ++ + P S S S S R S+ SR
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 391
Query: 907 GVSQEKEAQISSAIVSSVQSKITQD 931
K + S+ S +S+ +D
Sbjct: 392 SPRTSKTIKRKSSRSPSPRSRNKKD 416
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 73.2 bits (178), Expect = 1e-12
Identities = 138/589 (23%), Positives = 204/589 (34%), Gaps = 136/589 (23%)
Query: 420 PLPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVR 479
P PPP + SS + + +++S P PPPP P
Sbjct: 184 PAPPPAPSSASSSPSPSPSSSSPSPPP----PPPPPAPP--------------------- 218
Query: 480 AKNDQRFEFLQPWHQYNAYYE---FKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDA 536
A RF+ P+H + Y +Q + E S + SA +P + E+ +
Sbjct: 219 APPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEE 278
Query: 537 GEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKN 596
E+ ED E + S + + + D L + S A+ P
Sbjct: 279 EEE---EDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGT 335
Query: 597 RVKLDDDSDDD-------------EESKEGQESSSSAANTNPAVAPPCVVV---EEKKPQ 640
++D D E +EG+ S A+ PP + E ++ +
Sbjct: 336 PPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGE 395
Query: 641 LTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEK---------------QLQAERKR 685
+ Q E E + A AA A A+ ++ L AE
Sbjct: 396 IVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDG 455
Query: 686 KAALFLQTLKNPLPEAEAGK------------IEESPFSVEESSTTPCPLLTGGRPLPTL 733
+ AL + L P P A + + + S +P P P P
Sbjct: 456 EGALQVD-LGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPA-----PAPAA 509
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKH--------------KKRSRTRSRSPKYHSSSK 779
PP R S+ + E KE K+ R+R R P H+SS
Sbjct: 510 AAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSS 569
Query: 780 SR--SRSHSKAKHSLPSAYRTVRRSRS--RSRSPRRRAHSPERRREERSVPTAYRVSRSP 835
+R SRS S+++ T RRSRS R R RR+ S E+RR R + + S
Sbjct: 570 ARRRSRSRSRSR-------STRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSS 622
Query: 836 GASRKRTRSRSPH-----EKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSA 890
+SR R R R H KKKK+RSRSR + ++ S + AP PA P + S
Sbjct: 623 SSSR-RERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGS-----EKAPAPAPPPSGST--- 673
Query: 891 SVSPVESRGSSQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAKVRAM 939
S G R RG A+ S+Q DL A R +
Sbjct: 674 ------SCGDRDSRRRG-----------AVPPSIQDLTDHDLFAIKRTI 705
Score = 45.1 bits (105), Expect = 3e-04
Identities = 74/370 (20%), Positives = 125/370 (33%), Gaps = 83/370 (22%)
Query: 608 EESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKL 667
+ S E +E++SS++ T PA P + KK + +++ A R + +R +
Sbjct: 524 KRSGEAKEAASSSSGTQPAPPAPASPWDSKKHR-SRDRKPGSHASSSARRRSRSRSRSRS 582
Query: 668 AQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGG 727
+ S +++ R+ ++ + + SP
Sbjct: 583 TRRRSRSTDRRRGGSRRSRSR----------EKRRRRRRSASP----------------- 615
Query: 728 RPLPTLEVKPPDRPSSKSKDPPREEEKEKK---KKKHKKRSRTRSRSPKYHSSSK----- 779
PP SS S R K + KK KKRSR+R S K
Sbjct: 616 ---------PPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPA 666
Query: 780 -------------SRSRS------HSKAKHSLPSAYRTVRRSRSRSRSPR----RRAHSP 816
SR R H L + RT+ R PR A SP
Sbjct: 667 PPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSP 726
Query: 817 ERR---------REERSVPTAYRVSRSPGASRKRTRSRSPHEKKK--KRRSRSRTKSKAR 865
+R EER ++ + R GA+ + SR ++K R R + + R
Sbjct: 727 KREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDR 786
Query: 866 SQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAIVSSVQ 925
+ S K P+ +AP++ P S GS S ++ ++ S + ++
Sbjct: 787 DRDRSSKKARPPKESAPSS----GPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIR 842
Query: 926 SKITQDLMAK 935
++ AK
Sbjct: 843 EGVSSTTPAK 852
Score = 34.7 bits (78), Expect = 0.43
Identities = 88/419 (21%), Positives = 147/419 (35%), Gaps = 75/419 (17%)
Query: 512 GDSMQAVSAPE-EAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGK 570
G S S+P+ E DS + G + +D GA + S +E S + DG
Sbjct: 717 GPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGG 776
Query: 571 LVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPP 630
+++R + D D D D SK+ + SA ++ P PP
Sbjct: 777 -----------------------DRDRDR-DRDRDRDRSSKKARPPKESAPSSGPPPKPP 812
Query: 631 CVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALF 690
+ K KL+ ++A RE ++ + A+ A L
Sbjct: 813 V----SSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTT--------PAKDAASAGLG 860
Query: 691 LQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPR 750
+K FS + S +P P + P K+K +
Sbjct: 861 SIGVK---------------FSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAK 905
Query: 751 EEEKEKKKKKHK-KRSRTRSR---------SPKYHSSSKSRSRSHSKA---KHSLPSAYR 797
K+ K K K K S+TR + S S KS++ S S+A K + +++
Sbjct: 906 AGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWS 965
Query: 798 TVRRSRSRSRSPRRRAH------SPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKK 851
R+ +P +A +P+ + + S T VS P + + R E++
Sbjct: 966 GEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTP-EVSFLPEEATEEAGVRGGAEEE 1024
Query: 852 KKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQ 910
++ + + Q P+ A AA A +A SA + +S SR VSQ
Sbjct: 1025 EEEEEEEEEEEEEEEQ--QPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASR-VSQ 1080
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 73.2 bits (178), Expect = 1e-12
Identities = 69/238 (28%), Positives = 110/238 (46%), Gaps = 28/238 (11%)
Query: 636 EKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLK 695
+K P + + + K + L ++++ ++ SKE K K+ + ++++K +K
Sbjct: 275 KKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSR-SKERKSKRSETDKEKKP------IK 327
Query: 696 NPLPEAEAGKIEESPF-----SVEESSTTPCPLLTGGR---PLPTLEVKPPDRPSSKSKD 747
+P +A +GK SP S + S +P P R PL + S++
Sbjct: 328 SPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLS 387
Query: 748 PPREEEKEKKKKKHKKRSRTRSRSPKYHS-----SSKSRSRSHSKAKHSLPSAYRTV--- 799
P R + ++K ++ R R SP+ S + RS+ S P+ R+
Sbjct: 388 PGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPI 447
Query: 800 -RRSRS---RSRSPRRRAHSPERR-REERSVPTAYRVSRSPGASRKRTRSRSPHEKKK 852
RRSRS RSRSPRRR+ SP RR R RS R SRS G R+R+RS+ +K K
Sbjct: 448 RRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFK 505
Score = 63.2 bits (152), Expect = 1e-09
Identities = 67/272 (24%), Positives = 128/272 (47%), Gaps = 31/272 (11%)
Query: 649 KQAKQKLEDRLAAAAREKLAQASKESKEK-QLQAERKRKAALFLQTLKNPLPEAEAGKIE 707
K K K ++ + A+ +E ++ A + + L + +++ AL L N L E GK++
Sbjct: 74 KHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELME---GKVQ 130
Query: 708 ESPFSVEESSTTPCPLLTGGRPLPTLEVKPPD--RPSSKSKDPPREEEKEKKKKKHKKRS 765
+ + + G + K + R S++S + E K KKRS
Sbjct: 131 SGMGLILQGYES------GSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRS 184
Query: 766 RTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSV 825
++RS+ H S K +S+ + + R+ + R +S+SP +R+ S ++ R+ +S
Sbjct: 185 KSRSKERTRHRSDKKKSKGGIEIVKEKTT--RSKSKERKKSKSPSKRSKSQDQARKSKS- 241
Query: 826 PTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAH 885
PT R S+ K ++RSP + K K +S++K + +S ++ S+ +
Sbjct: 242 PTLRRRSQ-----EKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESR----------SR 286
Query: 886 SAHSASVSPVESRGSSQERSRGVSQEKEAQIS 917
S SPV+ RG S++R R S+E++++ S
Sbjct: 287 DRGKKSRSPVDLRGKSKDR-RSRSKERKSKRS 317
Score = 63.2 bits (152), Expect = 1e-09
Identities = 100/416 (24%), Positives = 161/416 (38%), Gaps = 54/416 (12%)
Query: 537 GEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKN 596
G + E+ E+ +A +G + SS T +LV K + E+
Sbjct: 139 GYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITT------KKRSKSRSKERT 192
Query: 597 RVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAK-QAKQKL 655
R + D ++SK G E + + E KK + + +++ QA++
Sbjct: 193 RHR-----SDKKKSKGGIEIVKEKTTRSKSK-------ERKKSKSPSKRSKSQDQARKSK 240
Query: 656 EDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEE 715
L ++EK+ +A + +K ++ + + N + GK SP +
Sbjct: 241 SPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRG 300
Query: 716 SSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKK-KKHKKRSRTRSRSPKY 774
S R + E K + K K P + K+ K+++ SR RSPK
Sbjct: 301 KSKD--------RRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKR 352
Query: 775 HS-SSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHS---------PERRR--EE 822
S S K R +S L +S SR+ SP RRA S PERRR
Sbjct: 353 RSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSP 412
Query: 823 RSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSP---SKQAAPRP 879
R+ P +SR R+R++ SP + R RSR S R +S SP S+ R
Sbjct: 413 RTRPRDDILSR-----RERSKDASPINRWSPTRRRSR--SPIRRRSRSPLRRSRSPRRRS 465
Query: 880 AAPAAHSAHSASVSPV----ESRGSSQERSRGVSQEKEAQISSAIVSSVQSKITQD 931
+P S S + SRG + RSR +E + + S + V+ + + D
Sbjct: 466 RSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSD 521
Score = 39.3 bits (90), Expect = 0.018
Identities = 46/215 (21%), Positives = 82/215 (38%), Gaps = 28/215 (13%)
Query: 745 SKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHS-KAKHSLPSAYRTVRRSR 803
S+D + + KKKKHK RS+ + HSS + + + H K KH + S
Sbjct: 32 SEDQSQNKHSRHKKKKHKHRSKHKKHK---HSSEEDKDKKHKHKHKHKKHKRKEIIDASD 88
Query: 804 SRSRSPRRRAHSP-----ERRREERSVPTAY--------RVSRSPGASRKRTRSRSPHEK 850
SP +R E ++R++ A +V G + S S E
Sbjct: 89 KEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEG 148
Query: 851 KKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQ 910
+ ++R+ +S RS S + + + S+ S+ER+R S
Sbjct: 149 EIHEKARNGNRSSTRSSSTKGKLEL-----------VDNKITTKKRSKSRSKERTRHRSD 197
Query: 911 EKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKN 945
+K+++ IV ++ K ++ SK+
Sbjct: 198 KKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKS 232
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 73.2 bits (178), Expect = 1e-12
Identities = 90/351 (25%), Positives = 140/351 (39%), Gaps = 60/351 (17%)
Query: 527 DSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAK 586
D P K D DG P DA E S K P K+ + + A+
Sbjct: 725 DGVPIKSLDDDLDGVPLDATE-------------DSKKNEPIFKVAPSKWE----AVDES 767
Query: 587 ENDLLPLEKNRVKL-DDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEE 645
E + + ++ +L D + +EE + QE S E+
Sbjct: 768 ELEAQAVTTSKWELFDQHEESEEEENQNQEEES-------------------------ED 802
Query: 646 LEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGK 705
E Q+ + E L + ++ SK SK ++ E++ K + E E+GK
Sbjct: 803 EEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGK 862
Query: 706 IEESPF-SVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKR 764
+ P S +E L LE +R K KD + E + K KK+ +
Sbjct: 863 RPKKPGQSFQEQVEHYRDKLLQREKEKELE---RERERDK-KDKEKLESRSKDKKEKDEC 918
Query: 765 SRTRSRSPKYHSSSKSRSRSHS--KAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREE 822
+ TR + HS+S S SRS S + K P + R+ R RS S R R+ + R+
Sbjct: 919 TPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRD- 977
Query: 823 RSVPTAYRVSRSPGASR-----KRTRSRSPHEKKKKRRSRSRTKSKARSQS 868
+ + RSP SR +R+RSRSP + KK RS+SR+ ++ +S
Sbjct: 978 ----VSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKS 1024
Score = 64.7 bits (156), Expect = 4e-10
Identities = 76/321 (23%), Positives = 136/321 (42%), Gaps = 43/321 (13%)
Query: 600 LDDDSDD-----DEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQ---A 651
LDDD D E+SK+ + P V K + + ELEA+ +
Sbjct: 732 LDDDLDGVPLDATEDSKKNE--------------PIFKVAPSKWEAVDESELEAQAVTTS 777
Query: 652 KQKLEDRLAAAAREKLAQASKESK-EKQLQAERKRKAALFLQTLKNPLPEAEAGKI---- 706
K +L D+ + E+ +ES+ E+ Q+ + + L+ +K + E++ K
Sbjct: 778 KWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMS 837
Query: 707 EESPFSVEESSTTPCP----LLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHK 762
EE + E L +G RP K P + + + R++ +++K+K
Sbjct: 838 EEKRAKLREIELKVMKFQDELESGKRP------KKPGQSFQEQVEHYRDKLLQREKEKEL 891
Query: 763 KRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREE 822
+R R R + K S+S+ + K K + +R S S SP R S RR +
Sbjct: 892 ERERERDKKDKEKLESRSKDK---KEKDECTPTRKERKRRHSTSPSPSR---SSSGRRVK 945
Query: 823 RSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAP 882
P + R RS + ++ +RSRS H+ + S+ +S + S++ S+++ R
Sbjct: 946 SPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKK 1005
Query: 883 AAHSAHSASVSPVESRGSSQE 903
+ + S S SP S S++
Sbjct: 1006 SGKKSRSQSRSPHRSHKKSKK 1026
Score = 53.5 bits (127), Expect = 9e-07
Identities = 66/283 (23%), Positives = 118/283 (41%), Gaps = 38/283 (13%)
Query: 516 QAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKAS 575
QAV+ + D E + ++ E E ++ + S+ + + ++
Sbjct: 772 QAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE--MTESK 829
Query: 576 FAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVE 635
F+ S + K L +E +K D+ + + K+ +S VE
Sbjct: 830 FSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQ-------------VE 876
Query: 636 EKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQ----LQAERKRKAALFL 691
+ +L Q E E + +++ D+ +EKL SK+ KEK + ERKR+ +
Sbjct: 877 HYRDKLLQREKEKELERERERDK---KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSP 933
Query: 692 --------QTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSS 743
+ +K+P P++E + E S S +ESS + + + P K R S
Sbjct: 934 SPSRSSSGRRVKSPSPKSE--RSERSERSHKESSRSR----SSHKDSPRDVSKKAKRSPS 987
Query: 744 KSKDPPREEE-KEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSH 785
S+ P R + + KK K+SR++SRSP + S KS+ H
Sbjct: 988 GSRTPKRSRRSRSRSPKKSGKKSRSQSRSP-HRSHKKSKKNKH 1029
Score = 37.7 bits (86), Expect = 0.051
Identities = 36/123 (29%), Positives = 49/123 (39%), Gaps = 29/123 (23%)
Query: 411 TAPPPPGTTP----------------LPPPTTAETSSGATSTTTTTSALAPVAAIIPPPP 454
T PPPP P LPPP E T + A V +IP
Sbjct: 373 TLPPPPSGLPFNAQPRERLKNPNAPMLPPPKNKEDFE-------KTLSQAIVKVVIPTER 425
Query: 455 DVQPVIDKLAEYVARNGLKFETSV--RAKNDQRFEFL-QPWHQYNAYYEFKKQFFLQKEG 511
++ +I ++ E+V R G FE + R N+ F FL + + YY +K LQ
Sbjct: 426 NLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSILQ--- 482
Query: 512 GDS 514
GDS
Sbjct: 483 GDS 485
Score = 36.6 bits (83), Expect = 0.11
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 183 ENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDF 242
+N+E F L ++ V +P + A+I R FV R+G FE M+ ++ N F F
Sbjct: 403 KNKEDFEKTLSQAIVK-VVIPTERNLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRF 461
Query: 243 L 243
L
Sbjct: 462 L 462
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 73.2 bits (178), Expect = 1e-12
Identities = 55/184 (29%), Positives = 91/184 (49%), Gaps = 11/184 (5%)
Query: 736 KPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSA 795
K +R +S R + KE+K + + SR+RSR ++ S S+ R +S S+++ S
Sbjct: 38 KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97
Query: 796 YRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRR 855
R+ R +SRSR S ER+R RS + R SR RTRSRS KK+ +
Sbjct: 98 SRSRERKKSRSR-------SRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 150
Query: 856 SRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQ 915
R ++S +R+ S P + R A A A + + + +E+ V ++K+ +
Sbjct: 151 PRRFSRSLSRTPSPPPFR---GRNTAMDAQEALARRLERAKKLQEQREKEM-VEKQKQQE 206
Query: 916 ISSA 919
I++A
Sbjct: 207 IAAA 210
Score = 72.8 bits (177), Expect = 1e-12
Identities = 58/194 (29%), Positives = 90/194 (46%), Gaps = 27/194 (13%)
Query: 746 KDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKA----KHSLPSAYRTVRR 801
K R E K+K KKHK + + K HSS K R R +S +H + R
Sbjct: 9 KQGRRHESKDKSSKKHK----SEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 64
Query: 802 SRSRSRSPRRRAHSPER-RREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKR------ 854
S SRSRS RR S R R++ RS + SRS RK++RSRS K++ R
Sbjct: 65 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 124
Query: 855 -------RSRSRTKSKARSQSVSPSK-----QAAPRPAAPAAHSAHSASVSPVESRGSSQ 902
RSRSRT+S++R + K ++ R +P + ++ E+
Sbjct: 125 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRL 184
Query: 903 ERSRGVSQEKEAQI 916
ER++ + +++E ++
Sbjct: 185 ERAKKLQEQREKEM 198
Score = 72.8 bits (177), Expect = 1e-12
Identities = 65/208 (31%), Positives = 94/208 (45%), Gaps = 16/208 (7%)
Query: 739 DRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSH-SKAKHSLPSAYR 797
D+ S K R E + +HK++ R SR + HS S+SR R H S+++ S R
Sbjct: 31 DKEHSSDKGRERLNSSENGEDRHKRKERKSSRG-RSHSRSRSRERRHRSRSRERKKSRSR 89
Query: 798 TVRRSRSRSRSPRR---RAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKR 854
+ R +SRSRS R R+ S ER+R RS SRS R RTRSRS + +
Sbjct: 90 SRERKKSRSRSRERKKSRSRSRERKRRIRSR------SRSRSRHRHRTRSRSRTRSRSRD 143
Query: 855 RSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEA 914
R + K + S+S+S + P A A A +E QE+ EK+
Sbjct: 144 RKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQK 203
Query: 915 QISSAIVSSVQSKITQDLMAKVRAMLAA 942
Q A ++ T + V A+LA+
Sbjct: 204 QQEIAAAAA-----TGGSVLNVAALLAS 226
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 72.8 bits (177), Expect = 1e-12
Identities = 106/439 (24%), Positives = 166/439 (37%), Gaps = 64/439 (14%)
Query: 528 SAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKAS----------FA 577
S P PS G A +G G G S + G + +S F
Sbjct: 747 SRPPAPSSHGS------LAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFR 800
Query: 578 PISFAIKAKEND--LLPLEKN---RVKLDDDSDD--DEESKEGQESSSSAANTNPAVAPP 630
P+ + KEN L ++K R ++ D SD + S G S P+
Sbjct: 801 PVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITR 860
Query: 631 CVVVEEKKPQ-------LTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAER 683
+ + K Q +T +E+ + ++A KL A + E
Sbjct: 861 TISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREE 920
Query: 684 KRKAALFLQTLKNPLP----EAEAGKIEESPFSVEESSTT----------PCPLLTGGRP 729
++ L+ P P + E G + F EE + T P P +
Sbjct: 921 PTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAAT 980
Query: 730 LPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAK 789
+E++PP R S+S R +K K+K+ ++ RTRS + S+SR RS A
Sbjct: 981 HRVVELRPPSR--SRSTSSSRSRKKAKRKRVSREHGRTRS-----GTRSESRDRSSRSAS 1033
Query: 790 HSLPSAYRTVRRSRSRS-RSPRRRAHSPERRREERSVPTAYRVSRSP-GASRKRTRSRS- 846
S+ +RS+++S RS R+ S ER + +++ + R P G SR+ +RSRS
Sbjct: 1034 PSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSG 1093
Query: 847 ----------PHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVE 896
KKKKRRS SR + + S + S + + +H S
Sbjct: 1094 SPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAW 1153
Query: 897 SRGSSQERSRGVSQEKEAQ 915
R + RSR S E A+
Sbjct: 1154 PRDRRKRRSRSPSSEHRAR 1172
Score = 65.5 bits (158), Expect = 2e-10
Identities = 66/238 (27%), Positives = 100/238 (42%), Gaps = 28/238 (11%)
Query: 662 AAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSV--EESSTT 719
AA ++ + S+ + + R RK A K E G+ S + SS +
Sbjct: 978 AATHRVVELRPPSRSRSTSSSRSRKKA------KRKRVSREHGRTRSGTRSESRDRSSRS 1031
Query: 720 PCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEK-KKKKHKKRSRTRSRSPKYHSSS 778
P + RP + + S+ R +E+ K+KK K +SR R P HS
Sbjct: 1032 ASPSVGEERPR-----RQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRR 1086
Query: 779 KSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSP----------ERRREERSVPTA 828
SRSRS S S ++ R + PR R SP + +RE
Sbjct: 1087 TSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPD 1146
Query: 829 YRVSRSPGASRKRTRSRSP---HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPA 883
+ S + R++ RSRSP H ++ RR RSR K +++S SP ++ A R A+PA
Sbjct: 1147 RKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREK-WPQTRSHSPERKGAVREASPA 1203
Score = 43.9 bits (102), Expect = 7e-04
Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
RP + P E+ + K ++RS R + + + R + S++ S A R
Sbjct: 1116 RPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRA-REH 1174
Query: 800 RRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTR 843
RR RSR + P+ R+HSPER+ R A PG TR
Sbjct: 1175 RRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTR 1218
Score = 37.7 bits (86), Expect = 0.051
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 805 RSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKA 864
R +PR A + R + VP + P A K + +RS KK++ R + R K
Sbjct: 327 RPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRS---KKRQHRVKKRRGKKV 383
Query: 865 RSQSVSPSKQAAPRPAAPAAHSAHSASV-SPVE 896
+S++ + S+ A HS+ SV PVE
Sbjct: 384 KSEATTRSRIARTLGLRRPVHSSCIPSVLKPVE 416
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 72.4 bits (176), Expect = 2e-12
Identities = 50/119 (42%), Positives = 67/119 (56%), Gaps = 10/119 (8%)
Query: 752 EEKEKKKKKHKKRSRTRSRSPKYH--------SSSKSRSRSHSKAKHSLPSAYRTVRRSR 803
EE++ KKK +RSR++SRS SSS+SRSRS S++ S S R+ R R
Sbjct: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
Query: 804 SRSRSPRRRAHSPERRREERSVPTAY-RVSRSPGASRKRTRSRSPHE-KKKKRRSRSRT 860
SRSR + R+ S R +Y S SP +RKR+RSRS +KKRR+RSR+
Sbjct: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS 307
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/158 (34%), Positives = 74/158 (46%), Gaps = 19/158 (12%)
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKH--- 790
E + D SK K E+E + K+ + S K S RSRS S++ H
Sbjct: 156 EEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNK--KKSNRRSRSKSRSSHSRS 213
Query: 791 ----SLPSAYRTVRRSRSRSRS---PRRRAHSPERRR----EERSVPTAYRVSRSPGASR 839
S PS+ R+ RSRSRS S R R+ S ER R + RS ++R S SP
Sbjct: 214 SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRS 273
Query: 840 KRTRSRSPHEKKKKRRSRSRT---KSKARSQSVSPSKQ 874
+ S SP +K+ RSRS + + K R++S SP Q
Sbjct: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPESQ 311
Score = 55.8 bits (133), Expect = 2e-07
Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 22/168 (13%)
Query: 751 EEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPR 810
E+E K K + + KY+ + S+ K + RRSRS+SRS
Sbjct: 160 EDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSN---------RRSRSKSRSSH 210
Query: 811 RRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVS 870
R+ S S P++ R SR R+RSRS + + RS SR +S++R
Sbjct: 211 SRSSS------RSSSPSSSR-------SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSR 257
Query: 871 PSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISS 918
S ++ ++P S S+S SP +R S+ RS K+ + S
Sbjct: 258 SSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS 305
Score = 38.9 bits (89), Expect = 0.023
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 848 HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHS-AHSASVSPVESRGSSQERSR 906
++KK RRSRS+++S S S S S+ ++P + + S + S+S S SR SS+ERSR
Sbjct: 194 NKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSR 250
Query: 907 GVSQEKEAQISSAIVSSVQSK 927
+ + S SS K
Sbjct: 251 SRGSKSRSSSRSHRGSSSPRK 271
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 72.0 bits (175), Expect = 2e-12
Identities = 107/453 (23%), Positives = 170/453 (37%), Gaps = 67/453 (14%)
Query: 531 EKPSDAG----------EDGAPEDAAEVGARA---GSGGKKEASSSKTVPDGKLVKASFA 577
EKP D G + G P + EVG SGG+ +A +S + G L K
Sbjct: 590 EKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSG-LNKQEPG 648
Query: 578 PISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEK 637
+ LP +K R S K+ ++ S+ + A EEK
Sbjct: 649 GSHGSETEDTGRSLPSKKER------SGKSHRHKKKKKHKKSSKHKRKHKAD----TEEK 698
Query: 638 --KPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLK 695
K + ++ + K+ K+K A A E+ + R+R+A Q
Sbjct: 699 SSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRS 758
Query: 696 NPLPEAEAGKIEES-------------------PFSVEESSTTPCPLLTGGRPLPTLEVK 736
P E +GK +E P S + + T + R P+ +
Sbjct: 759 LPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDE 818
Query: 737 PPDRPSSK---SKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLP 793
D SS K P + E+E+++ + SR+RSRS + HSS +S RS+S + +
Sbjct: 819 DSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDA-S 877
Query: 794 SAYRTVRRSRS-----------RSRSPRRRAHSPE-------RRREERSVPTAYRVSRSP 835
S R RS RSR +R+H + + R +R ++ S
Sbjct: 878 SDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSL 937
Query: 836 GASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPV 895
S+ R+RSRS ++ + R RSR+ S +RS+S S+ + + S S
Sbjct: 938 SCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTR 997
Query: 896 ESRGSSQERSRGVSQEKEAQISSAIVSSVQSKI 928
S R R E + S ++SKI
Sbjct: 998 SPSQRSGSRKRSWGHESPEERHSGRRDFIRSKI 1030
Score = 36.6 bits (83), Expect = 0.11
Identities = 79/412 (19%), Positives = 134/412 (32%), Gaps = 60/412 (14%)
Query: 519 SAPEEAPTDSAPEKPSDAGEDGAPE---------DAAEVGARAGSGGKKE---ASSSKTV 566
SAP ++ PE P +G P + A GS GKK+ SS
Sbjct: 722 SAPADSERGPKPEPPG-SGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD 780
Query: 567 PDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPA 626
G+ K P S +A K S + G E S A++
Sbjct: 781 HGGRKHKGELPPSSCQRRAG-----------TKRSSRSSHRSQPSSGDEDSDDASSHRLH 829
Query: 627 VAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQA----- 681
P EE++ + + E +++ ++R + +S S ++ +
Sbjct: 830 QKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSY 889
Query: 682 ---------ERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPT 732
+R R+ + + + + + +S + + + R
Sbjct: 890 SDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSH 949
Query: 733 LEVKPPDRPSSKSKDPPREEEKEK---------KKKKHKKRSRTRS-RSPKYHSSSKSRS 782
+ R S+S R K + ++ + R R+RS RSP S S+ RS
Sbjct: 950 TRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRS 1009
Query: 783 RSHSKAKHSLPSAYRTVRRSRSRSRSPR----RRAHSPERRREERSVPTAYRVSRSP--- 835
H + +R RS+SP R P ++ + R + S
Sbjct: 1010 WGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSN 1069
Query: 836 -GASRKRTRSRSPHEKK----KKRRSRSRTKSKARSQSVSPSKQAAPRPAAP 882
G R SP +K K + +++ R SVS QA P A P
Sbjct: 1070 IGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGP 1121
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 70.5 bits (171), Expect = 7e-12
Identities = 72/248 (29%), Positives = 104/248 (41%), Gaps = 17/248 (6%)
Query: 676 EKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEV 735
+++ A AA + T K P P G S S++ + R T
Sbjct: 336 DEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASR---TSSS 392
Query: 736 KPPDRPSSKSKDPPREEEKEKKKKKHKKR-SRTRSRSPKYHSSSKSRSRSHSKA------ 788
+ R SS+S+ + + + SR+RSRS +Y S S+SR R HS
Sbjct: 393 RSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRY-SRSRSRGRRHSGGGSRDGH 451
Query: 789 KHSLPSA----YRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRS 844
++S A Y RRSRSRS S R R S + S SP SR TRS
Sbjct: 452 RYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRS 511
Query: 845 RSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQER 904
RS +SRSR++S+++S S SP+++ RPAA A P + + +
Sbjct: 512 RS--HSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAK 569
Query: 905 SRGVSQEK 912
+ QEK
Sbjct: 570 PKLTPQEK 577
Score = 65.5 bits (158), Expect = 2e-10
Identities = 51/169 (30%), Positives = 76/169 (44%), Gaps = 34/169 (20%)
Query: 35 LLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWN 94
L V G ACK+ D ALA E +++PW GD +IDR+D R HL + +Y T
Sbjct: 41 LQVHGRACKVHLDSAVALAAESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTPPLLT-- 98
Query: 95 RDYQLSEEEARIEALCDEERYLAL----HTDLLEEEA---------------RQEEEYKR 135
+S E+ E C+ ERY L + EE+ E+E K+
Sbjct: 99 ---TISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGGLQRPSEDEKKK 155
Query: 136 LSEALAEDGSYNAVGFTYG----SDYYDPSEPTEEEEPSKQREKNEAEN 180
L+E A ++G+TY ++ +E EEEE + + E N E+
Sbjct: 156 LAEKKA------SIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDED 198
Score = 50.4 bits (119), Expect = 8e-06
Identities = 47/187 (25%), Positives = 77/187 (41%), Gaps = 18/187 (9%)
Query: 741 PSSKSKDPPREEEKEKKKKKHKKRSRTRSRSP------------KYHSSSKSRSRSHSKA 788
PS +D P + ++ + SR+RSRSP + S + + + + A
Sbjct: 287 PSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAA 346
Query: 789 KHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRS-- 846
S + + + +P R A + R S +A R S S +SR +RSR
Sbjct: 347 AASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGG 406
Query: 847 ---PHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRG-SSQ 902
+ + RSRS ++S++RS+ S S+ R + + H S SP G +
Sbjct: 407 GYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPR 466
Query: 903 ERSRGVS 909
RSR S
Sbjct: 467 RRSRSRS 473
Score = 41.6 bits (96), Expect = 0.004
Identities = 35/142 (24%), Positives = 51/142 (35%), Gaps = 5/142 (3%)
Query: 709 SPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTR 768
SP E T P G L E P P+ +EK K + +K +
Sbjct: 533 SPSPAREKLTRPAASPAVGEKLKKTE---PAAGKETGAAKPKLTPQEKLKLRMQKALNRQ 589
Query: 769 SRSPKYHSSSKSRSRSHSKAKHS--LPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVP 826
++ K + K + H + + L + R +R R R + R+ RS
Sbjct: 590 FKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPS 649
Query: 827 TAYRVSRSPGASRKRTRSRSPH 848
Y S R R+RSRSPH
Sbjct: 650 PRYSREYSSSRRRSRSRSRSPH 671
Score = 37.7 bits (86), Expect = 0.051
Identities = 39/145 (26%), Positives = 59/145 (40%), Gaps = 15/145 (10%)
Query: 785 HSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRS 844
H+KA + Y S RSR +RR +R R + P +Y SP +
Sbjct: 251 HAKALEEEKAMY-----SGRRSRR-QRREFREKRLRGRKISPPSYARRDSPTYDPYK--- 301
Query: 845 RSPHEKKKKRRSRSRTKSKARSQSVS------PSKQAAPRPAAPAAHSAHSASVSPVESR 898
RSP E + RSRSR+ + R + ++ S + A AA AA S + P +
Sbjct: 302 RSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQ 361
Query: 899 GSSQERSRGVSQEKEAQISSAIVSS 923
R S + + SS+ S+
Sbjct: 362 PGGPAPGRNASARRRSSSSSSSSSA 386
Score = 35.0 bits (79), Expect = 0.33
Identities = 61/264 (23%), Positives = 101/264 (38%), Gaps = 72/264 (27%)
Query: 551 RAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEES 610
R G G + SSS++ L + ++ + + ++R + S
Sbjct: 480 RRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPARE 539
Query: 611 KEGQESSSSAANTNPAVAPPCVVVEE--KKPQLTQEELEAKQAKQKLEDRLAAAAREKLA 668
K + ++S A P E KP+LT +E KL+ R+ A +
Sbjct: 540 KLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQE--------KLKLRMQKALNRQFK 591
Query: 669 QASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGR 728
K ++EK +Q E +R Q ++ L A A KI
Sbjct: 592 ADKKAAQEKMIQQEHER------QEREDEL-RAMARKIR--------------------- 623
Query: 729 PLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKA 788
+K +R RE+E+E+ ++++ ++SR S SP+Y SR +S +
Sbjct: 624 ------MKERER---------REKEREEWERQYSRQSR--SPSPRY-------SREYSSS 659
Query: 789 KHSLPSAYRTVRRSRSRSRSPRRR 812
+ RRSRSRSRSP R
Sbjct: 660 R----------RRSRSRSRSPHYR 673
Score = 30.4 bits (67), Expect = 8.2
Identities = 36/176 (20%), Positives = 69/176 (39%), Gaps = 8/176 (4%)
Query: 742 SSKSKDPPREEEKEKKKKKH----KKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYR 797
SS S P R + + + RSR+RSRS S S S +R + P+
Sbjct: 496 SSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRS---QSPSPSPAREKLTRPAASPAVGE 552
Query: 798 TVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSR 857
++++ + A +E+ + ++R A +K + + ++ +++
Sbjct: 553 KLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERE 612
Query: 858 SRTKSKARS-QSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEK 912
++ AR + ++ R +S S S SP SR S R R S+ +
Sbjct: 613 DELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 70.1 bits (170), Expect = 9e-12
Identities = 62/211 (29%), Positives = 90/211 (42%), Gaps = 28/211 (13%)
Query: 734 EVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSP-------KYHSSSKSRSRSHS 786
++ PP PSS+ K K+KKK KKR R+ S SP K S R RS S
Sbjct: 99 DLTPP--PSSRGK-------KKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFS 149
Query: 787 KAKHSLPSAYRTVRRSRSR-SRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSR 845
K + S+ ++ RR R + R R R R R + P + R R R
Sbjct: 150 KKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGR 209
Query: 846 SPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQE-- 903
SP E +K RR SR SK + SP Q++ P+ P + ++ + GS+ +
Sbjct: 210 SPEEGQKSRRRHSRRCSKTLCKD-SPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLF 268
Query: 904 --------RSRGVSQEKEAQISSAIVSSVQS 926
SRG SQE ++ ++ S Q+
Sbjct: 269 TKTASPLTTSRGRSQEYDSGNDTSSPPSTQT 299
Score = 65.5 bits (158), Expect = 2e-10
Identities = 83/342 (24%), Positives = 133/342 (38%), Gaps = 44/342 (12%)
Query: 592 PLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQA 651
PL +R + + ++ S +SSA + P + + + + ++ +
Sbjct: 274 PLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS 333
Query: 652 KQKLEDRLAAAAREKLAQASKESKEKQLQ------AERKRKAALFLQTLKNPLPEAEAGK 705
+ A E L+ S+ + + Q AE K+ + + +P+
Sbjct: 334 FTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSS 393
Query: 706 IEESPFSVEESSTTP----CPLLTGGRPLPTLEVKPPDRPSSKSKD----PPREEEKEKK 757
S S SS +P P T R + + PS SK PP + ++
Sbjct: 394 SYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRR 453
Query: 758 KKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSP- 816
+ + S +R R PKY S S+ R +A+ RR RS S +RR SP
Sbjct: 454 SPSYSRYSPSRERDPKY-SEKDSQQRERERAR----------RRRRSYSPMRKRRRDSPS 502
Query: 817 --ERRR----EERSVPTAYRVSRSPGASRKRTRS-------RSPHEKKKKRRSRSRTKSK 863
E RR +R +P YR S S S T S RS + RSRSR++ +
Sbjct: 503 HLEARRITSARKRPIPY-YRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRR 561
Query: 864 ARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERS 905
+R+++ S S +P P + + S S S SR SQ RS
Sbjct: 562 SRTRTSSSSSSRSPSPGS----RSRSRSRSRSRSRSRSQSRS 599
Score = 58.5 bits (140), Expect = 3e-08
Identities = 59/210 (28%), Positives = 85/210 (40%), Gaps = 9/210 (4%)
Query: 742 SSKSKDP-PREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVR 800
S S+ P PR + + + R+ SRSP Y S S RS ++ +Y R
Sbjct: 402 SHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYS--R 459
Query: 801 RSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRT 860
S SR R P+ ++R ER A R RS RKR R H + RR S
Sbjct: 460 YSPSRERDPKYSEKDSQQRERER----ARRRRRSYSPMRKRRRDSPSH--LEARRITSAR 513
Query: 861 KSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAI 920
K SPS + + S+ S S S SR S+ RSR S+ + + SS+
Sbjct: 514 KRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSR 573
Query: 921 VSSVQSKITQDLMAKVRAMLAASKNLQTSA 950
S S+ ++ R+ + +SA
Sbjct: 574 SPSPGSRSRSRSRSRSRSRSRSQSRSYSSA 603
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/210 (27%), Positives = 92/210 (43%), Gaps = 34/210 (16%)
Query: 695 KNPLPEAEAGKIEESPFSVEESSTTPCPLLT---GGRPLPTLEVKPPDRPS------SKS 745
++P P A + S E+ S + P + G R P+ + PS S+
Sbjct: 406 RSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRE 465
Query: 746 KDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRS-----RSHSKAKHSLP------- 793
+DP E+ +++++ + R R RS SP S S R S K +P
Sbjct: 466 RDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPS 525
Query: 794 --------SAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPG-ASRKRTRS 844
S++ + SRS SRS R RR R+ ++ SRSP SR R+RS
Sbjct: 526 SSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRS 585
Query: 845 RSPHEKKKKRRSRSRTKSKARSQSVSPSKQ 874
RS + + RSRS+++S + + S S +++
Sbjct: 586 RS----RSRSRSRSQSRSYSSADSYSSTRR 611
Score = 50.4 bits (119), Expect = 8e-06
Identities = 46/195 (23%), Positives = 89/195 (45%), Gaps = 11/195 (5%)
Query: 724 LTGGRPLPTLEVKPPDRPSSKSKDPPREE-EKEKKKKKHKKRSRTRSRSPKYHSSSKSRS 782
+T +PLP E P + P ++D P E+ + + S R ++ + +++ S
Sbjct: 36 ITARKPLPRTE--PQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHS 93
Query: 783 RSHSKAKHSLPSAYRTVRRSRSRSRSPRRRA--HSPERRREERSVPTAYRVSRSPGASRK 840
SH K PS+ R ++ + +R RRR+ +SP ++++ + R + ++
Sbjct: 94 ASHDKDLTPPPSS-RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKR 152
Query: 841 RTRSRSPH-----EKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPV 895
R S SP EK+ K++SRSR + R + ++ + P++ + SP
Sbjct: 153 RHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPE 212
Query: 896 ESRGSSQERSRGVSQ 910
E + S + SR S+
Sbjct: 213 EGQKSRRRHSRRCSK 227
Score = 50.4 bits (119), Expect = 8e-06
Identities = 74/338 (21%), Positives = 122/338 (36%), Gaps = 66/338 (19%)
Query: 513 DSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPD---- 568
DS S+P T SA + E G+P SG ++ +S T
Sbjct: 286 DSGNDTSSPPSTQTSSARSRGQ---EKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNK 342
Query: 569 ------------GKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQES 616
G+ + +P + K++ L+P + S + + S
Sbjct: 343 GAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAST-RSS 401
Query: 617 SSSAANTNPAVAPPCV----VVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASK 672
S S+ + NP +P EK+ +K K+ R + + R
Sbjct: 402 SHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYS 461
Query: 673 ESKEKQLQ------AERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTG 726
S+E+ + +R+R+ A + +P+ + +SP +E T
Sbjct: 462 PSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRR----RDSPSHLEARRITSARK--- 514
Query: 727 GRPLPTLEVKPPDR----------PSSKSKDPPREEEKEKKKKKHKKRSRTR------SR 770
RP+P P SS S+ R + + + + ++RSRTR SR
Sbjct: 515 -RPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSR 573
Query: 771 SPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRS 808
SP S S+SRSRS S++ RSRS+SRS
Sbjct: 574 SPSPGSRSRSRSRSRSRS------------RSRSQSRS 599
Score = 31.6 bits (70), Expect = 3.7
Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 1/86 (1%)
Query: 832 SRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSAS 891
+R AS + + P + KK++ +S K + RS S SPS + + H S
Sbjct: 89 TRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK-RRRS 147
Query: 892 VSPVESRGSSQERSRGVSQEKEAQIS 917
S SS +S+ +++ + S
Sbjct: 148 FSKKRRHSSSSPKSKRRDEKRHKKQS 173
Score = 31.6 bits (70), Expect = 3.7
Identities = 47/241 (19%), Positives = 85/241 (35%), Gaps = 4/241 (1%)
Query: 680 QAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPD 739
Q R+R + +TL PEA++ + P + + + G
Sbjct: 215 QKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASP 274
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
+S+ + + + + S RSR + S S S+S + + +
Sbjct: 275 LTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSF 334
Query: 800 RRSRSRSRSPRRRAHSPERR-REERSV--PTAYRVSRSPGASRKRTRSRSPHEKKKKRRS 856
S +++ SP R RE R P + T SP + + S
Sbjct: 335 TTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSS 394
Query: 857 RSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQI 916
+ T+S + S S SP+ +A+PR + S+ S S S S + S+ ++
Sbjct: 395 YASTRSSSHS-SRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRR 453
Query: 917 S 917
S
Sbjct: 454 S 454
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 67.8 bits (164), Expect = 5e-11
Identities = 97/449 (21%), Positives = 172/449 (38%), Gaps = 51/449 (11%)
Query: 518 VSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKE---ASSSKTVPDGKLVKA 574
V A +AP A P A A ++ + + ++E A+ KTVP ++V
Sbjct: 192 VKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAK 251
Query: 575 SFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSA-ANTNPAVAPPCVV 633
AP+ A P K+ D SD++EE K+ ++ ++ P APP
Sbjct: 252 --APVKAATT-------PTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPP--- 299
Query: 634 VEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERK--RKAALFL 691
KK TQ +A + +Q +E ++ S + + + E+K KA +
Sbjct: 300 --PKKSLGTQPPKKAVEKQQPVES----------SEDSSDESDSSSEEEKKPPTKAVVSK 347
Query: 692 QTLKNPLPEAEAGKIEESPFSV----EESSTTPCPLLTGGRPLPTLEVKPPD-RPSSKSK 746
T K P + A +S S +E+ + P P + K P +P++ K
Sbjct: 348 ATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK 407
Query: 747 DPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSK----SRSRSHSKAKHSLPSAYRTVRRS 802
P +K +K S S S + + K ++ ++ +KA SLP A + + S
Sbjct: 408 QPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLP-AKQAPQGS 466
Query: 803 RSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKS 862
R S + E + +S V + P P KK + S + S
Sbjct: 467 RDSSSDSDSSSSEEEEEKTSKSA-----VKKKPQKVAGGAAPSKPASAKKGKAESSNSSS 521
Query: 863 KARSQSVSPSK---QAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSA 919
S K + +PRP AP A+ + + ++ +S+E ++K+A + +
Sbjct: 522 SDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEE---EEKKKAAVVVS 578
Query: 920 IVSSVQSKITQDLMAKVRAMLAASKNLQT 948
S++ + + + A LQT
Sbjct: 579 KSGSLKKRKQNEAAKEAETPQAKKIKLQT 607
Score = 63.2 bits (152), Expect = 1e-09
Identities = 142/674 (21%), Positives = 235/674 (34%), Gaps = 111/674 (16%)
Query: 253 YKFIQKAMKEGRYTVLAENKSDEK-KKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLE 311
Y F K+ K + A +K KK SSD+ED +EE+ P+ A+ R+
Sbjct: 54 YSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRV- 112
Query: 312 ELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPSQVEYTADSTVAAMYYSYY 371
P KA SS+ + D Q Q
Sbjct: 113 -----------GLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKG------------ 149
Query: 372 MLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNS-PGVT-------TTAPPPPGTTP--L 421
+ P APP + + N P +T T APP P +
Sbjct: 150 VKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKI 209
Query: 422 PPPTTAETSSGATSTTTTTSALAPVAAIIPPP--PDVQPVIDKLAEYVARNGLKFETSVR 479
A +SS ++S++++ + AA P P Q V + K +S
Sbjct: 210 ANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSED 269
Query: 480 AKNDQRFEFLQPWHQYNAYYEF---------KKQFFLQ--KEGGDSMQAVSAPEEAPTDS 528
+ +D+ E +P Y KK Q K+ + Q P E+ DS
Sbjct: 270 SSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQ----PVESSEDS 325
Query: 529 APEKPSDAGEDGAP----------------EDAAEVGARAGSGGKKEASSSKTVPDGKLV 572
+ E S + E+ P + AAE + + E + + P G
Sbjct: 326 SDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTK 385
Query: 573 KASFAPI----SFAIKAKENDLLPL---EKNRVKLDDDSDDDEESKEGQESSSSAANTNP 625
+S P S A+K P+ +K + D S +EES +E +
Sbjct: 386 NSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKK----- 440
Query: 626 AVAPPCVVVEEKKPQLTQE---ELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAE 682
+V KP+ T + L AKQA Q D ++ + + +S+E +EK ++
Sbjct: 441 -------MVATTKPKATAKAALSLPAKQAPQGSRD----SSSDSDSSSSEEEEEKTSKSA 489
Query: 683 RKRKAALFLQTLKNPLP-EAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRP 741
K+K P A+ GK E S S + S+ G+ P + +
Sbjct: 490 VKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGT 549
Query: 742 SS-------KSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPS 794
S+ +K+ EEE++KK +S + + + ++ ++ + K K P+
Sbjct: 550 SALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPN 609
Query: 795 AYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGAS--------RKRTRSRS 846
+ ++ R+ SP RR E + R ++ R K T+ +S
Sbjct: 610 TFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKS 669
Query: 847 -PHEKKKKRRSRSR 859
HEK KK+R R
Sbjct: 670 FRHEKTKKKRGSYR 683
Score = 60.1 bits (144), Expect = 1e-08
Identities = 95/444 (21%), Positives = 162/444 (36%), Gaps = 68/444 (15%)
Query: 529 APEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTV--PDGKLVKASFAPISFAIKAK 586
A +K S + + + E+ EV G KK A +K V P GK A KA
Sbjct: 78 AKKKASSSDSEDSSEEEEEV---QGPPAKKAAVPAKRVGLPPGKA----------AAKAS 124
Query: 587 ENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVV------------- 633
E+ + + D DD+E+ K+ A APP
Sbjct: 125 ES-------SSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED 177
Query: 634 --VEEKKPQLTQEELEAK--------QAKQKLEDRLAAAAREKLAQASK--ESKEKQLQA 681
+ +KP++T ++A+ +A K+ + AA++ + +S +S+E++ A
Sbjct: 178 EPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAA 237
Query: 682 ERKRKAALFLQTLKNPL-----PEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVK 736
K+ K P+ P ++ E+S EE P +P P V
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMK----NKPGPYSSVP 293
Query: 737 PPDRPSSKSK---DPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLP 793
PP P K PP++ ++++ + + S S S SKA P
Sbjct: 294 PPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPP 353
Query: 794 SAYRTVRRSRSRSRS--------PRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSR 845
A + S S S P + A + + + +V T + A ++
Sbjct: 354 PAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG 413
Query: 846 SPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPA-AHSAHSASVSPVESRGSSQER 904
+K S S +S + + + A +P A A A + A +P SR SS +
Sbjct: 414 QKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDS 473
Query: 905 SRGVSQEKEAQISSAIVSSVQSKI 928
S+E+E + S + V K+
Sbjct: 474 DSSSSEEEEEKTSKSAVKKKPQKV 497
Score = 55.8 bits (133), Expect = 2e-07
Identities = 69/312 (22%), Positives = 126/312 (40%), Gaps = 53/312 (16%)
Query: 648 AKQAKQKLEDRLAAAAREKLAQASKESK-----EKQLQAERKRKAALFLQTLKNPLPEA- 701
AK ++KL+ A + K +S +S+ E+++Q +KAA+ + + P +A
Sbjct: 61 AKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAA 120
Query: 702 ----EAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKK 757
E+ EES +E P+ G +P PP + S D E E
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPP 180
Query: 758 KKKHKK------RSRTRS------RSPKY---------HSSSKSRSRSHSKAKHSLPSAY 796
K + K +++T++ +PK SSS S S S+ + + +
Sbjct: 181 KNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPK 240
Query: 797 RTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRS 856
+TV + + +++P + A +P R+ +S + + S E+KK ++
Sbjct: 241 KTVPKKQVVAKAPVKAATTPTRK----------------SSSSEDSSSDEEEEQKKPMKN 284
Query: 857 RSRTKSKARSQSVSPSKQA-APRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQ 915
+ S S P K++ +P A PVES S + S S+E++
Sbjct: 285 KPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQ-----QPVESSEDSSDESDSSSEEEKKP 339
Query: 916 ISSAIVSSVQSK 927
+ A+VS +K
Sbjct: 340 PTKAVVSKATTK 351
Score = 53.5 bits (127), Expect = 9e-07
Identities = 83/388 (21%), Positives = 136/388 (35%), Gaps = 55/388 (14%)
Query: 602 DDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEEL-----EAKQAKQKLE 656
+DS ++EE +G + +A PP + + EE E Q KQ ++
Sbjct: 88 EDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQ 147
Query: 657 DRL-----AAAAREKLAQASKESKEKQLQAERKRK-------AALFLQTLKNPLPEAEAG 704
+ AA A K A++S + + E + + QT P P A
Sbjct: 148 KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAP 207
Query: 705 KI--------------EESPFSVEESSTTPCPLLTGGR-----PLPTLEVKPPDRPSSKS 745
KI S EE P T + P P R SS S
Sbjct: 208 KIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSS 267
Query: 746 KDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSR 805
+D +EE+E+KK K P +SS S K + V + +
Sbjct: 268 EDSSSDEEEEQKKPMKNK--------PGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPV 319
Query: 806 SRSPRRRAHSPERRREERSVPTAYRVSRS---PGASRKRTRSRSPHEKKKKRRSRSRTKS 862
S S EE+ PT VS++ P ++K S S S S
Sbjct: 320 ESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD-----SDSSEDD 374
Query: 863 KARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAIVS 922
+A S+ +K ++ +PA A + +P + G Q+ ++++ ++ S S
Sbjct: 375 EAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL---LTRKADSSSSEEESS 431
Query: 923 SVQSKITQDLMAKVRAMLAASKNLQTSA 950
S + + T+ ++A + A L A
Sbjct: 432 SSEEEKTKKMVATTKPKATAKAALSLPA 459
>gi|116812577 LUC7-like 2 [Homo sapiens]
Length = 392
Score = 67.0 bits (162), Expect = 8e-11
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 22/173 (12%)
Query: 746 KDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSR 805
K R +E+ K++++ ++ R + R + HS + RSRS +H RSRS
Sbjct: 235 KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH----------RSRSM 284
Query: 806 SRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSR---TKS 862
SR +RR S R + R SRS SR R+ RS H + + R RS+ +K
Sbjct: 285 SRERKRRTRSKSREKRHR------HRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKE 338
Query: 863 KARSQSV-SPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEA 914
+ R Q + S + + R +P S + G S++R S+E+EA
Sbjct: 339 RFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRS--SEEREA 389
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/140 (32%), Positives = 67/140 (47%), Gaps = 18/140 (12%)
Query: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
R S SK+P R +E ++ RSR+ SR K + SKSR + H +R+
Sbjct: 260 RSRSHSKNPKRSRSREHRRH----RSRSMSRERKRRTRSKSREKRH---------RHRSR 306
Query: 800 RRSRSRSRSPRRRAHSPERRREERSVPTA----YRVSRSPGASRKR-TRSRSPHEKKKKR 854
SRSRSRS +R HS R ERS + +R R R +R RSP ++ +K
Sbjct: 307 SSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKD 366
Query: 855 RSRSRTKSKARSQSVSPSKQ 874
+ RS + RS+ S++
Sbjct: 367 KKRSYESANGRSEDRRSSEE 386
Score = 46.6 bits (109), Expect = 1e-04
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Query: 797 RTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRS 856
+ V + R+ R ER REER R SRS + KR+RSR + RR
Sbjct: 229 KRVVAEKQEKRNQERLKRREEREREERE---KLRRSRSHSKNPKRSRSR------EHRRH 279
Query: 857 RSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQ 915
RSR+ S+ R + + SK R + S+ S S S SR SS++RSR S+ + ++
Sbjct: 280 RSRSMSRERKRR-TRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK 337
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 67.0 bits (162), Expect = 8e-11
Identities = 59/192 (30%), Positives = 97/192 (50%), Gaps = 21/192 (10%)
Query: 738 PDRPSSKSKDPPREEEKEKKKKKHKK-RSRTRSRSPKYHSSSKSRSR-----SHSKAKHS 791
PDR K+ EE+EK++++ ++ R R R R + ++R R S S+++HS
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 792 LPSAYRTVRRSR----SRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSP 847
++ R RSR SRSR RRR+ S +RRR RS + R RS R+R++SR
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRE-RRRSRSRDRRR-SRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 848 HEKKKKRRSRSR---TKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPV-----ESRG 899
K + +SR R KSK + + S K+++ + + S + + S E G
Sbjct: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNG 418
Query: 900 SSQE-RSRGVSQ 910
+S++ +S G +Q
Sbjct: 419 TSEDIKSEGDTQ 430
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/183 (28%), Positives = 84/183 (45%), Gaps = 31/183 (16%)
Query: 744 KSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSR 803
K ++ REE + K++++ ++R + R+R + S+SRSR S+ S R +RSR
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSR 318
Query: 804 SRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSK 863
SR R RR+ S +RRR SRS S ++ RSRS + +RRS+SR +
Sbjct: 319 SRER---RRSRSRDRRR-----------SRSHDRSERKHRSRS----RDRRRSKSRDRKS 360
Query: 864 ARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAIVSS 923
+ +S S ++ E RGS ++S S +E Q S
Sbjct: 361 YKHRSKSRDRE-------------QDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407
Query: 924 VQS 926
+S
Sbjct: 408 KES 410
Score = 57.4 bits (137), Expect = 6e-08
Identities = 57/234 (24%), Positives = 99/234 (42%), Gaps = 27/234 (11%)
Query: 638 KPQLTQEELEAKQAKQKLE-DRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKN 696
K + T EEL+ K K+ E DR +EK + +E + ++ + ER+RK + +
Sbjct: 222 KIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREK 281
Query: 697 PLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEK 756
+ S S T+ DR S+S+D R +E+
Sbjct: 282 ERARDRERRKRSRSRSRHSSRTS-------------------DRRCSRSRDHKRSRSRER 322
Query: 757 KKKKHKKRSRTRS--RSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAH 814
++ + + R R+RS RS + H +SRSR ++K +Y+ RS+SR R R++
Sbjct: 323 RRSRSRDRRRSRSHDRSERKH---RSRSRDRRRSKSRDRKSYK--HRSKSRDREQDRKSK 377
Query: 815 SPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQS 868
E+R + + SR + T S+ K + + KS+ +QS
Sbjct: 378 EKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
Score = 51.2 bits (121), Expect = 4e-06
Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 10/170 (5%)
Query: 755 EKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAH 814
E+ K+K +KR+ R + + R + + R +R R + RA
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERER--KRRREEEEREKERAR 285
Query: 815 SPERRREER------SVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQS 868
ERR+ R S + R SRS R R+R R + +RRSRS +S+ + +S
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS 345
Query: 869 VSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISS 918
S ++ + + ++ S S + R S ++ RG S +K++ + S
Sbjct: 346 RSRDRRRS-KSRDRKSYKHRSKSRDREQDRKSKEKEKRG-SDDKKSSVKS 393
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,859,137
Number of Sequences: 37866
Number of extensions: 2541501
Number of successful extensions: 47466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 515
Number of HSP's successfully gapped in prelim test: 1411
Number of HSP's that attempted gapping in prelim test: 22336
Number of HSP's gapped (non-prelim): 14792
length of query: 951
length of database: 18,247,518
effective HSP length: 112
effective length of query: 839
effective length of database: 14,006,526
effective search space: 11751475314
effective search space used: 11751475314
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.