Guide to the Human Genome
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Search of human proteins with 23110964

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23110964 cathepsin W preproprotein [Homo sapiens]
         (376 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23110964 cathepsin W preproprotein [Homo sapiens]                  791   0.0  
gi|6042196 cathepsin F [Homo sapiens]                                 238   5e-63
gi|23110957 cathepsin H isoform b precursor [Homo sapiens]            153   2e-37
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]        153   3e-37
gi|23110962 cathepsin S preproprotein [Homo sapiens]                  137   2e-32
gi|23110960 cathepsin L2 preproprotein [Homo sapiens]                 129   4e-30
gi|4557501 cathepsin O preproprotein [Homo sapiens]                   128   1e-29
gi|22202619 cathepsin L1 preproprotein [Homo sapiens]                 127   2e-29
gi|4503155 cathepsin L1 preproprotein [Homo sapiens]                  127   2e-29
gi|4503151 cathepsin K preproprotein [Homo sapiens]                   125   5e-29
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]       107   2e-23
gi|22538437 cathepsin B preproprotein [Homo sapiens]                   74   3e-13
gi|22538435 cathepsin B preproprotein [Homo sapiens]                   74   3e-13
gi|22538433 cathepsin B preproprotein [Homo sapiens]                   74   3e-13
gi|22538431 cathepsin B preproprotein [Homo sapiens]                   74   3e-13
gi|4503139 cathepsin B preproprotein [Homo sapiens]                    74   3e-13
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]       71   2e-12
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa...    69   5e-12
gi|22538442 cathepsin Z preproprotein [Homo sapiens]                   69   7e-12
gi|41281943 hypothetical protein LOC753 isoform alpha 1 [Homo sa...    35   0.14 
gi|41281957 hypothetical protein LOC753 isoform alpha 2 [Homo sa...    35   0.14 
gi|4757884 hypothetical protein LOC753 isoform beta 1 [Homo sapi...    35   0.14 
gi|41281948 hypothetical protein LOC753 isoform beta 2 [Homo sap...    35   0.14 
gi|51093710 hypothetical protein LOC753 isoform gamma 2 [Homo sa...    35   0.14 
gi|51093708 hypothetical protein LOC753 isoform gamma 1 [Homo sa...    35   0.14 
gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]       32   0.93 
gi|239755930 PREDICTED: hypothetical protein XP_002344747 [Homo ...    30   3.5  
gi|239750450 PREDICTED: hypothetical protein [Homo sapiens]            30   3.5  
gi|239744752 PREDICTED: hypothetical protein XP_002343247 [Homo ...    30   3.5  
gi|109638751 ubiquitin specific protease 6 [Homo sapiens]              30   3.5  

>gi|23110964 cathepsin W preproprotein [Homo sapiens]
          Length = 376

 Score =  791 bits (2044), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MALTAHPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHA 60
           MALTAHPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHA
Sbjct: 1   MALTAHPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHA 60

Query: 61  HRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIR 120
           HRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIR
Sbjct: 61  HRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIR 120

Query: 121 SEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQE 180
           SEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQE
Sbjct: 121 SEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQE 180

Query: 181 LLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDF 240
           LLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDF
Sbjct: 181 LLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDF 240

Query: 241 IMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGS 300
           IMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGS
Sbjct: 241 IMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGS 300

Query: 301 VKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLT 360
           VKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLT
Sbjct: 301 VKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLT 360

Query: 361 ARVQKPDMKPRVSCPP 376
           ARVQKPDMKPRVSCPP
Sbjct: 361 ARVQKPDMKPRVSCPP 376


>gi|6042196 cathepsin F [Homo sapiens]
          Length = 484

 Score =  238 bits (608), Expect = 5e-63
 Identities = 129/339 (38%), Positives = 185/339 (54%), Gaps = 34/339 (10%)

Query: 28  AQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFG 87
           +QDL   P+++   FK F I +NR+Y S EE   RL +F +N+ +AQ++Q  D GTA++G
Sbjct: 176 SQDL---PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYG 232

Query: 88  VTPFSDLTEEEFGQLY---GYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPI 144
           VT FSDLTEEEF  +Y     R+  G      + +    P E      DWR   GA++ +
Sbjct: 233 VTKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPE-----WDWRS-KGAVTKV 286

Query: 145 KDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFITVL 204
           KDQ  C  CWA +  GN+E  W ++    + +S QELLDC +    C GG   +A+  + 
Sbjct: 287 KDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIK 346

Query: 205 NNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTI 264
           N  GL +E DY +QG +++  C+    +   +I D + L  NE ++A +LA  GPI+V I
Sbjct: 347 NLGGLETEDDYSYQGHMQS--CNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAI 404

Query: 265 NMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPT 324
           N   +Q YR G+ +     C P L+DH+VLLVG+G+                        
Sbjct: 405 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSD--------------------V 444

Query: 325 PYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTARV 363
           P+W +KNSWG  WGEKGY+ LHRGS  CG+     +A V
Sbjct: 445 PFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVV 483


>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
          Length = 323

 Score =  153 bits (387), Expect = 2e-37
 Identities = 103/335 (30%), Positives = 160/335 (47%), Gaps = 36/335 (10%)

Query: 26  LRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLG--T 83
           L A +L    LE K  FK +  +  ++Y S EE+ HRL  FA N    +++   + G  T
Sbjct: 8   LCAAELCVNSLE-KFHFKSWMSKHRKTY-STEEYHHRLQTFASNW---RKINAHNNGNHT 62

Query: 84  AEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISP 143
            +  +  FSD++  E    Y +        +    +R   P    P S DWRK    +SP
Sbjct: 63  FKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGP---YPPSVDWRKKGNFVSP 119

Query: 144 IKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRC--GDGCHGGFVWDAFI 201
           +K+Q  C  CW  +  G +E+   I+    + ++ Q+L+DC +     GC GG    AF 
Sbjct: 120 VKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFE 179

Query: 202 TVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQ-NNEHRIAQYLATYGPI 260
            +L N G+  E  YP+QGK    +  P K   + +++D   +   +E  + + +A Y P+
Sbjct: 180 YILYNKGIMGEDTYPYQGKDGYCKFQPGK--AIGFVKDVANITIYDEEAMVEAVALYNPV 237

Query: 261 TVTINM-KPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQ 319
           +    + +   +YR G+  +T     P  V+H+VL VG+G    + GI            
Sbjct: 238 SFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGE---KNGI------------ 282

Query: 320 PPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGI 354
                PYWI+KNSWG QWG  GYF + RG N CG+
Sbjct: 283 -----PYWIVKNSWGPQWGMNGYFLIERGKNMCGL 312


>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
          Length = 335

 Score =  153 bits (386), Expect = 3e-37
 Identities = 97/319 (30%), Positives = 153/319 (47%), Gaps = 35/319 (10%)

Query: 42  FKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLG--TAEFGVTPFSDLTEEEF 99
           FK +  +  ++Y S EE+ HRL  FA N    +++   + G  T +  +  FSD++  E 
Sbjct: 35  FKSWMSKHRKTY-STEEYHHRLQTFASNW---RKINAHNNGNHTFKMALNQFSDMSFAEI 90

Query: 100 GQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAA 159
              Y +        +    +R   P    P S DWRK    +SP+K+Q  C  CW  +  
Sbjct: 91  KHKYLWSEPQNCSATKSNYLRGTGP---YPPSVDWRKKGNFVSPVKNQGACGSCWTFSTT 147

Query: 160 GNIETLWRISFWDFVDVSVQELLDCGRC--GDGCHGGFVWDAFITVLNNSGLASEKDYPF 217
           G +E+   I+    + ++ Q+L+DC +     GC GG    AF  +L N G+  E  YP+
Sbjct: 148 GALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPY 207

Query: 218 QGKVRAHRCHPKKYQKVAWIQDFIMLQ-NNEHRIAQYLATYGPITVTINM-KPLQLYRKG 275
           QGK    +  P K   + +++D   +   +E  + + +A Y P++    + +   +YR G
Sbjct: 208 QGKDGYCKFQPGK--AIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTG 265

Query: 276 VIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGA 335
           +  +T     P  V+H+VL VG+G    + GI                 PYWI+KNSWG 
Sbjct: 266 IYSSTSCHKTPDKVNHAVLAVGYGE---KNGI-----------------PYWIVKNSWGP 305

Query: 336 QWGEKGYFRLHRGSNTCGI 354
           QWG  GYF + RG N CG+
Sbjct: 306 QWGMNGYFLIERGKNMCGL 324


>gi|23110962 cathepsin S preproprotein [Homo sapiens]
          Length = 331

 Score =  137 bits (345), Expect = 2e-32
 Identities = 94/303 (31%), Positives = 144/303 (47%), Gaps = 44/303 (14%)

Query: 65  IFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGRE--IRSE 122
           +  HNL  +  +   DLG    G     D+T EE   L    R    VPS  +       
Sbjct: 59  VMLHNLEHSMGMHSYDLGMNHLG-----DMTSEEVMSLMSSLR----VPSQWQRNITYKS 109

Query: 123 EPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELL 182
            P   +P S DWR+  G ++ +K Q +C  CWA +A G +E   ++     V +S Q L+
Sbjct: 110 NPNRILPDSVDWRE-KGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV 168

Query: 183 DCG--RCGD-GCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRC-HPKKYQKVAWIQ 238
           DC   + G+ GC+GGF+  AF  +++N G+ S+  YP+  K    +C +  KY+     +
Sbjct: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPY--KAMDQKCQYDSKYRAATCSK 226

Query: 239 DFIMLQNNEHRIAQYLATYGPITVTINMK--PLQLYRKGVIKATPTTCDPQLVDHSVLLV 296
              +    E  + + +A  GP++V ++ +     LYR GV      T   Q V+H VL+V
Sbjct: 227 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT---QNVNHGVLVV 283

Query: 297 GFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRG-SNTCGIT 355
           G+G +  +E                    YW++KNSWG  +GE+GY R+ R   N CGI 
Sbjct: 284 GYGDLNGKE--------------------YWLVKNSWGHNFGEEGYIRMARNKGNHCGIA 323

Query: 356 KFP 358
            FP
Sbjct: 324 SFP 326


>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
          Length = 334

 Score =  129 bits (324), Expect = 4e-30
 Identities = 91/270 (33%), Positives = 132/270 (48%), Gaps = 30/270 (11%)

Query: 91  FSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNC 150
           F D+T EEF Q+ G  R        G+  R E     +P S DWRK  G ++P+K+QK C
Sbjct: 80  FGDMTNEEFRQMMGCFRNQKF--RKGKVFR-EPLFLDLPKSVDWRK-KGYVTPVKNQKQC 135

Query: 151 NCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRC--GDGCHGGFVWDAFITVLNNSG 208
             CWA +A G +E          V +S Q L+DC R     GC+GGF+  AF  V  N G
Sbjct: 136 GSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGG 195

Query: 209 LASEKDYPFQGKVRAHRCHPKKYQKVAWIQDF-IMLQNNEHRIAQYLATYGPITVTINM- 266
           L SE+ YP+       +  P+    VA    F ++    E  + + +AT GPI+V ++  
Sbjct: 196 LDSEESYPYVAVDEICKYRPEN--SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAG 253

Query: 267 -KPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTP 325
               Q Y+ G+       C  + +DH VL+VG+G          E  +S +       + 
Sbjct: 254 HSSFQFYKSGIY--FEPDCSSKNLDHGVLVVGYGF---------EGANSNN-------SK 295

Query: 326 YWILKNSWGAQWGEKGYFRLHRGSNT-CGI 354
           YW++KNSWG +WG  GY ++ +  N  CGI
Sbjct: 296 YWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325


>gi|4557501 cathepsin O preproprotein [Homo sapiens]
          Length = 321

 Score =  128 bits (321), Expect = 1e-29
 Identities = 84/278 (30%), Positives = 126/278 (45%), Gaps = 35/278 (12%)

Query: 83  TAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAIS 142
           TA +G+  FS L  EEF  +Y  R      P    E+    P  S+P   DWR     ++
Sbjct: 64  TAFYGINQFSYLFPEEFKAIY-LRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQ-VVT 121

Query: 143 PIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFIT 202
            +++Q+ C  CWA +  G +E+ + I      D+SVQ+++DC     GC+GG   +A + 
Sbjct: 122 QVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCSYNNYGCNGGSTLNA-LN 180

Query: 203 VLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAW------IQDFIMLQNNEHRIAQYLAT 256
            LN   +   KD  +  K +   CH        +        DF    + E  +A+ L T
Sbjct: 181 WLNKMQVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAYDF---SDQEDEMAKALLT 237

Query: 257 YGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQS 316
           +GP+ V ++    Q Y  G+I+     C     +H+VL+ GF    S             
Sbjct: 238 FGPLVVIVDAVSWQDYLGGIIQHH---CSSGEANHAVLITGFDKTGS------------- 281

Query: 317 QPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGI 354
                  TPYWI++NSWG+ WG  GY  +  GSN CGI
Sbjct: 282 -------TPYWIVRNSWGSSWGVDGYAHVKMGSNVCGI 312


>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  127 bits (319), Expect = 2e-29
 Identities = 97/326 (29%), Positives = 155/326 (47%), Gaps = 35/326 (10%)

Query: 38  LKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQ-RLQEEDLGTAEF--GVTPFSDL 94
           L+  +  ++   NR Y   EE   R  ++  N+   +   QE   G   F   +  F D+
Sbjct: 25  LEAQWTKWKAMHNRLYGMNEEGWRRA-VWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 83

Query: 95  TEEEFGQLY-GYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCC 153
           T EEF Q+  G++      P  G+ +  E      P S DWR+  G ++P+K+Q  C  C
Sbjct: 84  TSEEFRQVMNGFQNRK---PRKGK-VFQEPLFYEAPRSVDWRE-KGYVTPVKNQGQCGSC 138

Query: 154 WAMAAAGNIETLWRISFWDFVDVSVQELLDCG--RCGDGCHGGFVWDAFITVLNNSGLAS 211
           WA +A G +E          + +S Q L+DC   +  +GC+GG +  AF  V +N GL S
Sbjct: 139 WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS 198

Query: 212 EKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM--KPL 269
           E+ YP++    + + +PK    VA    F+ +   E  + + +AT GPI+V I+   +  
Sbjct: 199 EESYPYEATEESCKYNPK--YSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESF 256

Query: 270 QLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWIL 329
             Y++G+       C  + +DH VL+VG+G   +E                     YW++
Sbjct: 257 LFYKEGIY--FEPDCSSEDMDHGVLVVGYGFESTES----------------DNNKYWLV 298

Query: 330 KNSWGAQWGEKGYFRLHRG-SNTCGI 354
           KNSWG +WG  GY ++ +   N CGI
Sbjct: 299 KNSWGEEWGMGGYVKMAKDRRNHCGI 324


>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  127 bits (319), Expect = 2e-29
 Identities = 97/326 (29%), Positives = 155/326 (47%), Gaps = 35/326 (10%)

Query: 38  LKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQ-RLQEEDLGTAEF--GVTPFSDL 94
           L+  +  ++   NR Y   EE   R  ++  N+   +   QE   G   F   +  F D+
Sbjct: 25  LEAQWTKWKAMHNRLYGMNEEGWRRA-VWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 83

Query: 95  TEEEFGQLY-GYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCC 153
           T EEF Q+  G++      P  G+ +  E      P S DWR+  G ++P+K+Q  C  C
Sbjct: 84  TSEEFRQVMNGFQNRK---PRKGK-VFQEPLFYEAPRSVDWRE-KGYVTPVKNQGQCGSC 138

Query: 154 WAMAAAGNIETLWRISFWDFVDVSVQELLDCG--RCGDGCHGGFVWDAFITVLNNSGLAS 211
           WA +A G +E          + +S Q L+DC   +  +GC+GG +  AF  V +N GL S
Sbjct: 139 WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS 198

Query: 212 EKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM--KPL 269
           E+ YP++    + + +PK    VA    F+ +   E  + + +AT GPI+V I+   +  
Sbjct: 199 EESYPYEATEESCKYNPK--YSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESF 256

Query: 270 QLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWIL 329
             Y++G+       C  + +DH VL+VG+G   +E                     YW++
Sbjct: 257 LFYKEGIY--FEPDCSSEDMDHGVLVVGYGFESTES----------------DNNKYWLV 298

Query: 330 KNSWGAQWGEKGYFRLHRG-SNTCGI 354
           KNSWG +WG  GY ++ +   N CGI
Sbjct: 299 KNSWGEEWGMGGYVKMAKDRRNHCGI 324


>gi|4503151 cathepsin K preproprotein [Homo sapiens]
          Length = 329

 Score =  125 bits (315), Expect = 5e-29
 Identities = 91/296 (30%), Positives = 138/296 (46%), Gaps = 38/296 (12%)

Query: 65  IFAHNLAQAQRLQEEDLG--TAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSE 122
           I  HNL       E  LG  T E  +    D+T EE  Q     +           +   
Sbjct: 57  ISIHNL-------EASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIP 109

Query: 123 EPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELL 182
           E E   P S D+RK  G ++P+K+Q  C  CWA ++ G +E   +      +++S Q L+
Sbjct: 110 EWEGRAPDSVDYRK-KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLV 168

Query: 183 DCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPK-KYQKVAWIQDFI 241
           DC    DGC GG++ +AF  V  N G+ SE  YP+ G+  +   +P  K  K    ++  
Sbjct: 169 DCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYRE-- 226

Query: 242 MLQNNEHRIAQYLATYGPITVTI--NMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFG 299
           + + NE  + + +A  GP++V I  ++   Q Y KGV      +C+   ++H+VL VG+G
Sbjct: 227 IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVY--YDESCNSDNLNHAVLAVGYG 284

Query: 300 SVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRG-SNTCGI 354
             K  +                    +WI+KNSWG  WG KGY  + R  +N CGI
Sbjct: 285 IQKGNK--------------------HWIIKNSWGENWGNKGYILMARNKNNACGI 320


>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
          Length = 463

 Score =  107 bits (267), Expect = 2e-23
 Identities = 92/330 (27%), Positives = 147/330 (44%), Gaps = 54/330 (16%)

Query: 55  SPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGG--- 111
           S E++++RL  + HN  +A    ++      +  T + +      G +    R +GG   
Sbjct: 159 SQEKYSNRLYKYDHNFVKAINAIQKS-----WTATTYMEYETLTLGDMI---RRSGGHSR 210

Query: 112 -VPSMGREIRSEEPEESV---PFSCDWRKVAGA--ISPIKDQKNCNCCWAMAAAGNIETL 165
            +P       + E ++ +   P S DWR V G   +SP+++Q +C  C++ A+ G +E  
Sbjct: 211 KIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEAR 270

Query: 166 WRISFWDFVD--VSVQELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQG---- 219
            RI   +     +S QE++ C +   GC GGF +        + GL  E  +P+ G    
Sbjct: 271 IRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSP 330

Query: 220 ---KVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINMKPLQL-YRKG 275
              K    R +  +Y  V           NE  +   L  +GP+ V   +    L Y+KG
Sbjct: 331 CKMKEDCFRYYSSEYHYVGGFYGGC----NEALMKLELVHHGPMAVAFEVYDDFLHYKKG 386

Query: 276 VIKATPTTCDP----QLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKN 331
           +   T    DP    +L +H+VLLVG+G+  S  G+                  YWI+KN
Sbjct: 387 IYHHTGLR-DPFNPFELTNHAVLLVGYGT-DSASGM-----------------DYWIVKN 427

Query: 332 SWGAQWGEKGYFRLHRGSNTCGITKFPLTA 361
           SWG  WGE GYFR+ RG++ C I    + A
Sbjct: 428 SWGTGWGENGYFRIRRGTDECAIESIAVAA 457


>gi|22538437 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 64/250 (25%), Positives = 98/250 (39%), Gaps = 60/250 (24%)

Query: 141 ISPIKDQKNCNCCWAMAAAGNIETLWRI--SFWDFVDVSVQELLDC--GRCGDGCHGGFV 196
           I  I+DQ +C  CWA  A   I     I  +    V+VS ++LL C    CGDGC+GG+ 
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 197 WDAFITVLNNSGLAS-------------------------------EKDYPFQGKVRAHR 225
            +A+       GL S                               E D P   K+    
Sbjct: 156 AEAW-NFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 226 CHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM-KPLQLYRKGVIKATPTTC 284
             P   Q   +  +   + N+E  I   +   GP+    ++     LY+ GV +      
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVT--- 271

Query: 285 DPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFR 344
              +  H++ ++G+G    E G                 TPYW++ NSW   WG+ G+F+
Sbjct: 272 GEMMGGHAIRILGWGV---ENG-----------------TPYWLVANSWNTDWGDNGFFK 311

Query: 345 LHRGSNTCGI 354
           + RG + CGI
Sbjct: 312 ILRGQDHCGI 321


>gi|22538435 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 64/250 (25%), Positives = 98/250 (39%), Gaps = 60/250 (24%)

Query: 141 ISPIKDQKNCNCCWAMAAAGNIETLWRI--SFWDFVDVSVQELLDC--GRCGDGCHGGFV 196
           I  I+DQ +C  CWA  A   I     I  +    V+VS ++LL C    CGDGC+GG+ 
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 197 WDAFITVLNNSGLAS-------------------------------EKDYPFQGKVRAHR 225
            +A+       GL S                               E D P   K+    
Sbjct: 156 AEAW-NFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 226 CHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM-KPLQLYRKGVIKATPTTC 284
             P   Q   +  +   + N+E  I   +   GP+    ++     LY+ GV +      
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVT--- 271

Query: 285 DPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFR 344
              +  H++ ++G+G    E G                 TPYW++ NSW   WG+ G+F+
Sbjct: 272 GEMMGGHAIRILGWGV---ENG-----------------TPYWLVANSWNTDWGDNGFFK 311

Query: 345 LHRGSNTCGI 354
           + RG + CGI
Sbjct: 312 ILRGQDHCGI 321


>gi|22538433 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 64/250 (25%), Positives = 98/250 (39%), Gaps = 60/250 (24%)

Query: 141 ISPIKDQKNCNCCWAMAAAGNIETLWRI--SFWDFVDVSVQELLDC--GRCGDGCHGGFV 196
           I  I+DQ +C  CWA  A   I     I  +    V+VS ++LL C    CGDGC+GG+ 
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 197 WDAFITVLNNSGLAS-------------------------------EKDYPFQGKVRAHR 225
            +A+       GL S                               E D P   K+    
Sbjct: 156 AEAW-NFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 226 CHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM-KPLQLYRKGVIKATPTTC 284
             P   Q   +  +   + N+E  I   +   GP+    ++     LY+ GV +      
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVT--- 271

Query: 285 DPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFR 344
              +  H++ ++G+G    E G                 TPYW++ NSW   WG+ G+F+
Sbjct: 272 GEMMGGHAIRILGWGV---ENG-----------------TPYWLVANSWNTDWGDNGFFK 311

Query: 345 LHRGSNTCGI 354
           + RG + CGI
Sbjct: 312 ILRGQDHCGI 321


>gi|22538431 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 64/250 (25%), Positives = 98/250 (39%), Gaps = 60/250 (24%)

Query: 141 ISPIKDQKNCNCCWAMAAAGNIETLWRI--SFWDFVDVSVQELLDC--GRCGDGCHGGFV 196
           I  I+DQ +C  CWA  A   I     I  +    V+VS ++LL C    CGDGC+GG+ 
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 197 WDAFITVLNNSGLAS-------------------------------EKDYPFQGKVRAHR 225
            +A+       GL S                               E D P   K+    
Sbjct: 156 AEAW-NFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 226 CHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM-KPLQLYRKGVIKATPTTC 284
             P   Q   +  +   + N+E  I   +   GP+    ++     LY+ GV +      
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVT--- 271

Query: 285 DPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFR 344
              +  H++ ++G+G    E G                 TPYW++ NSW   WG+ G+F+
Sbjct: 272 GEMMGGHAIRILGWGV---ENG-----------------TPYWLVANSWNTDWGDNGFFK 311

Query: 345 LHRGSNTCGI 354
           + RG + CGI
Sbjct: 312 ILRGQDHCGI 321


>gi|4503139 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 64/250 (25%), Positives = 98/250 (39%), Gaps = 60/250 (24%)

Query: 141 ISPIKDQKNCNCCWAMAAAGNIETLWRI--SFWDFVDVSVQELLDC--GRCGDGCHGGFV 196
           I  I+DQ +C  CWA  A   I     I  +    V+VS ++LL C    CGDGC+GG+ 
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 197 WDAFITVLNNSGLAS-------------------------------EKDYPFQGKVRAHR 225
            +A+       GL S                               E D P   K+    
Sbjct: 156 AEAW-NFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 226 CHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM-KPLQLYRKGVIKATPTTC 284
             P   Q   +  +   + N+E  I   +   GP+    ++     LY+ GV +      
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVT--- 271

Query: 285 DPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFR 344
              +  H++ ++G+G    E G                 TPYW++ NSW   WG+ G+F+
Sbjct: 272 GEMMGGHAIRILGWGV---ENG-----------------TPYWLVANSWNTDWGDNGFFK 311

Query: 345 LHRGSNTCGI 354
           + RG + CGI
Sbjct: 312 ILRGQDHCGI 321


>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
          Length = 476

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 76/330 (23%), Positives = 126/330 (38%), Gaps = 67/330 (20%)

Query: 74  QRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCD 133
           +++ + D G      + F  +T E+     G++   G +P     +   E   S+P + D
Sbjct: 162 EQVNKGDYGWTAQNYSQFWGMTLED-----GFKFRLGTLPPSPMLLSMNEMTASLPATTD 216

Query: 134 WR-------KVAGAISPIKDQKNCNCCWAMAAAG------NIETLWRISFWDFVDVSVQE 180
                    K  G      DQKNC   WA + A        I++  R +     ++S Q 
Sbjct: 217 LPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYT----ANLSPQN 272

Query: 181 LLDC-GRCGDGCHGGFVWDAFITVLNNSGLASEKDYPF-----------------QGKVR 222
           L+ C  +   GC+ G + D     L   GL S   YP                   G+ +
Sbjct: 273 LISCCAKNRHGCNSGSI-DRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGK 331

Query: 223 AHRCHP-----KKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINMKP-LQLYRKGV 276
            H   P     +K  ++        + +NE  I + +   GP+   + ++     Y+ G+
Sbjct: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGI 391

Query: 277 IKATPTTCDP-----QLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKN 331
            +   +T        +L  H+V L G+G+++  +G                   +WI  N
Sbjct: 392 YRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQG---------------QKEKFWIAAN 436

Query: 332 SWGAQWGEKGYFRLHRGSNTCGITKFPLTA 361
           SWG  WGE GYFR+ RG N   I K  + A
Sbjct: 437 SWGKSWGENGYFRILRGVNESDIEKLIIAA 466


>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
           sapiens]
          Length = 467

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 71/259 (27%), Positives = 97/259 (37%), Gaps = 52/259 (20%)

Query: 146 DQKNCNCCWAMAAAGNIETLWRISFWDFVD--VSVQELLDCG-RCGDGCHGGFVWDAFIT 202
           DQ NC   WA + A        I     +   +S Q LL C      GC GG + D    
Sbjct: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRL-DGAWW 280

Query: 203 VLNNSGLASEKDYPFQGKVR-----AHRCH-----------------PKKY---QKVAWI 237
            L   G+ S+  YPF G+ R     A  C                  P  Y     +  +
Sbjct: 281 FLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQV 340

Query: 238 QDFIMLQNNEHRIAQYLATYGPITVTINM-KPLQLYRKGVIKATPTTCD-PQLV----DH 291
                L +N+  I + L   GP+   + + +   LY+ G+   TP +   P+       H
Sbjct: 341 TPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTH 400

Query: 292 SVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNT 351
           SV + G+G     +G                   YW   NSWG  WGE+G+FR+ RG N 
Sbjct: 401 SVKITGWGEETLPDG---------------RTLKYWTAANSWGPAWGERGHFRIVRGVNE 445

Query: 352 CGITKFPL--TARVQKPDM 368
           C I  F L    RV   DM
Sbjct: 446 CDIESFVLGVWGRVGMEDM 464


>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
          Length = 303

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 72/271 (26%), Positives = 106/271 (39%), Gaps = 59/271 (21%)

Query: 105 YRRAAG-GVPSMGREIRSEEPE----ESVPFSCDWRKVAGA--ISPIKDQ---KNCNCCW 154
           YR   G G+  +GR       E      +P S DWR V G    S  ++Q   + C  CW
Sbjct: 34  YRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCW 93

Query: 155 AMAAAGNIE---TLWRISFWDFVDVSVQELLDCGRCGDGCHGG---FVWDAFITVLNNSG 208
           A A+   +     + R   W    +SVQ ++DCG  G  C GG    VWD      +  G
Sbjct: 94  AHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGS-CEGGNDLSVWD----YAHQHG 148

Query: 209 LASEKDYPFQGKVRA-------------HRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLA 255
           +  E    +Q K +                CH  +   +  + D+  L   E  +A+  A
Sbjct: 149 IPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYA 208

Query: 256 TYGPITVTINM-KPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSS 314
             GPI+  I   + L  Y  G+        D   ++H V + G+G     E         
Sbjct: 209 N-GPISCGIMATERLANYTGGIYAEYQ---DTTYINHVVSVAGWGISDGTE--------- 255

Query: 315 QSQPQPPHPTPYWILKNSWGAQWGEKGYFRL 345
                      YWI++NSWG  WGE+G+ R+
Sbjct: 256 -----------YWIVRNSWGEPWGERGWLRI 275


>gi|41281943 hypothetical protein LOC753 isoform alpha 1 [Homo
           sapiens]
          Length = 306

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 258 GPITVTIN--MKPLQLYRKGVIKATP--TTCDPQLVDHSVLLVGFGSVKSEEGIWAETVS 313
           GP T+ +    + ++L R+ V +A P  T  D  L+D ++   G     S  GI A T S
Sbjct: 185 GPCTLQLRDPEQQMELNRESV-RAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCS 243

Query: 314 SQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGS------NTCGITKFPLTARVQKP 366
           S  + + P PT   ++ +  GA +        HRGS      N    T  P+  + +KP
Sbjct: 244 SNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTIVPIKGKDRKP 302


>gi|41281957 hypothetical protein LOC753 isoform alpha 2 [Homo
           sapiens]
          Length = 288

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 258 GPITVTIN--MKPLQLYRKGVIKATP--TTCDPQLVDHSVLLVGFGSVKSEEGIWAETVS 313
           GP T+ +    + ++L R+ V +A P  T  D  L+D ++   G     S  GI A T S
Sbjct: 167 GPCTLQLRDPEQQMELNRESV-RAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCS 225

Query: 314 SQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGS------NTCGITKFPLTARVQKP 366
           S  + + P PT   ++ +  GA +        HRGS      N    T  P+  + +KP
Sbjct: 226 SNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTIVPIKGKDRKP 284


>gi|4757884 hypothetical protein LOC753 isoform beta 1 [Homo
           sapiens]
          Length = 248

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 258 GPITVTIN--MKPLQLYRKGVIKATP--TTCDPQLVDHSVLLVGFGSVKSEEGIWAETVS 313
           GP T+ +    + ++L R+ V +A P  T  D  L+D ++   G     S  GI A T S
Sbjct: 127 GPCTLQLRDPEQQMELNRESV-RAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCS 185

Query: 314 SQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGS------NTCGITKFPLTARVQKP 366
           S  + + P PT   ++ +  GA +        HRGS      N    T  P+  + +KP
Sbjct: 186 SNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTIVPIKGKDRKP 244


>gi|41281948 hypothetical protein LOC753 isoform beta 2 [Homo
           sapiens]
          Length = 230

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 258 GPITVTIN--MKPLQLYRKGVIKATP--TTCDPQLVDHSVLLVGFGSVKSEEGIWAETVS 313
           GP T+ +    + ++L R+ V +A P  T  D  L+D ++   G     S  GI A T S
Sbjct: 109 GPCTLQLRDPEQQMELNRESV-RAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCS 167

Query: 314 SQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGS------NTCGITKFPLTARVQKP 366
           S  + + P PT   ++ +  GA +        HRGS      N    T  P+  + +KP
Sbjct: 168 SNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTIVPIKGKDRKP 226


>gi|51093710 hypothetical protein LOC753 isoform gamma 2 [Homo
           sapiens]
          Length = 251

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 258 GPITVTIN--MKPLQLYRKGVIKATP--TTCDPQLVDHSVLLVGFGSVKSEEGIWAETVS 313
           GP T+ +    + ++L R+ V +A P  T  D  L+D ++   G     S  GI A T S
Sbjct: 130 GPCTLQLRDPEQQMELNRESV-RAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCS 188

Query: 314 SQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGS------NTCGITKFPLTARVQKP 366
           S  + + P PT   ++ +  GA +        HRGS      N    T  P+  + +KP
Sbjct: 189 SNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTIVPIKGKDRKP 247


>gi|51093708 hypothetical protein LOC753 isoform gamma 1 [Homo
           sapiens]
          Length = 269

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 258 GPITVTIN--MKPLQLYRKGVIKATP--TTCDPQLVDHSVLLVGFGSVKSEEGIWAETVS 313
           GP T+ +    + ++L R+ V +A P  T  D  L+D ++   G     S  GI A T S
Sbjct: 148 GPCTLQLRDPEQQMELNRESV-RAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCS 206

Query: 314 SQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGS------NTCGITKFPLTARVQKP 366
           S  + + P PT   ++ +  GA +        HRGS      N    T  P+  + +KP
Sbjct: 207 SNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTIVPIKGKDRKP 265


>gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]
          Length = 1117

 Score = 32.0 bits (71), Expect = 0.93
 Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 26/95 (27%)

Query: 276 VIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQ----------PQPPH--- 322
           V+   PTT   QL+   +LL G   +  EEG+  + V+  S           P PP    
Sbjct: 91  VLTPQPTTVGAQLLGAPLLLTGLVGMNEEEGVQEDVVAEASSAIQPGTKTPGPPPPRGAQ 150

Query: 323 ---PTPYWILKNSW----------GAQWGEKGYFR 344
              P P ++ + S            A WG  GY+R
Sbjct: 151 PLLPLPRYLRRASSHLLPADAVYDHALWGLHGYYR 185


>gi|239755930 PREDICTED: hypothetical protein XP_002344747 [Homo
           sapiens]
          Length = 64

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 299 GSVKSEEGIWAETVSSQSQPQPPHPT 324
           G   + EG W  T+SS+  PQPP PT
Sbjct: 2   GRSAAGEGPWLYTMSSEVLPQPPSPT 27


>gi|239750450 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 64

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 299 GSVKSEEGIWAETVSSQSQPQPPHPT 324
           G   + EG W  T+SS+  PQPP PT
Sbjct: 2   GRSAAGEGPWLYTMSSEVLPQPPSPT 27


>gi|239744752 PREDICTED: hypothetical protein XP_002343247 [Homo
           sapiens]
          Length = 64

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 299 GSVKSEEGIWAETVSSQSQPQPPHPT 324
           G   + EG W  T+SS+  PQPP PT
Sbjct: 2   GRSAAGEGPWLYTMSSEVLPQPPSPT 27


>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
          Length = 1406

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)

Query: 6   HPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDI 65
           H S L+  +  G+   IRGP+ +  L  Q ++LK   + +QI   R   S  EH H +D+
Sbjct: 89  HSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIKLKNPGR-YQIMKERGKRS-SEHIHHIDL 146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,094,445
Number of Sequences: 37866
Number of extensions: 747727
Number of successful extensions: 1905
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1828
Number of HSP's gapped (non-prelim): 38
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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