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Search of human proteins with 229577238
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens]
(1121 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens] 2244 0.0
gi|70980549 programmed cell death 11 [Homo sapiens] 50 1e-05
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 48 5e-05
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ... 48 5e-05
gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens] 46 2e-04
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 44 7e-04
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 40 0.009
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 40 0.009
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 40 0.009
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 40 0.009
gi|118402596 cell division cycle protein 23 [Homo sapiens] 40 0.012
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 39 0.036
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 39 0.036
gi|83415184 transmembrane and tetratricopeptide repeat containin... 38 0.047
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 38 0.062
gi|118402578 anaphase-promoting complex, subunit 6 [Homo sapiens] 37 0.080
gi|118402580 anaphase-promoting complex, subunit 6 [Homo sapiens] 37 0.080
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 37 0.10
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 37 0.14
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 37 0.14
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 37 0.14
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 36 0.18
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 36 0.18
gi|4557719 DNA ligase I [Homo sapiens] 36 0.23
gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap... 35 0.31
gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap... 35 0.31
gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap... 35 0.31
gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap... 35 0.31
gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapi... 35 0.31
gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens] 35 0.31
>gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens]
Length = 1121
Score = 2244 bits (5814), Expect = 0.0
Identities = 1121/1121 (100%), Positives = 1121/1121 (100%)
Query: 1 MEQVPSAGRLVQITVTEGYDLKGFKGDTPVTFIRAEFNQVVLGDSAKITVSPEGSAKYNF 60
MEQVPSAGRLVQITVTEGYDLKGFKGDTPVTFIRAEFNQVVLGDSAKITVSPEGSAKYNF
Sbjct: 1 MEQVPSAGRLVQITVTEGYDLKGFKGDTPVTFIRAEFNQVVLGDSAKITVSPEGSAKYNF 60
Query: 61 TSSFEFNPEGGITSDDLAHKPVFLTVTEVLPKEKKQKEEKTLILGQAVVDLLPLLEGQSS 120
TSSFEFNPEGGITSDDLAHKPVFLTVTEVLPKEKKQKEEKTLILGQAVVDLLPLLEGQSS
Sbjct: 61 TSSFEFNPEGGITSDDLAHKPVFLTVTEVLPKEKKQKEEKTLILGQAVVDLLPLLEGQSS 120
Query: 121 FQTTVPLHPVQGSPLETPRSSAKQCSLEVKVLVAEPLLTTAQISGGNLLKVTLEAAYSVP 180
FQTTVPLHPVQGSPLETPRSSAKQCSLEVKVLVAEPLLTTAQISGGNLLKVTLEAAYSVP
Sbjct: 121 FQTTVPLHPVQGSPLETPRSSAKQCSLEVKVLVAEPLLTTAQISGGNLLKVTLEAAYSVP 180
Query: 181 ESFIPTGPGQNYMVGLQVPSLGEKDYPILFKNGTLKLGGEREPVPRPKKWPIANILAPGA 240
ESFIPTGPGQNYMVGLQVPSLGEKDYPILFKNGTLKLGGEREPVPRPKKWPIANILAPGA
Sbjct: 181 ESFIPTGPGQNYMVGLQVPSLGEKDYPILFKNGTLKLGGEREPVPRPKKWPIANILAPGA 240
Query: 241 NNIPDAFIVGGPYEEEEGELNHPEDSEFRNQAECIKKRIIWDLESRCYLDPSAVVSFQKR 300
NNIPDAFIVGGPYEEEEGELNHPEDSEFRNQAECIKKRIIWDLESRCYLDPSAVVSFQKR
Sbjct: 241 NNIPDAFIVGGPYEEEEGELNHPEDSEFRNQAECIKKRIIWDLESRCYLDPSAVVSFQKR 300
Query: 301 IADCRLWPVEITRVPLVTIPKGKAGKTEKTDEEAQLSFHGVAYVNMVPLLYPGVKRIRGA 360
IADCRLWPVEITRVPLVTIPKGKAGKTEKTDEEAQLSFHGVAYVNMVPLLYPGVKRIRGA
Sbjct: 301 IADCRLWPVEITRVPLVTIPKGKAGKTEKTDEEAQLSFHGVAYVNMVPLLYPGVKRIRGA 360
Query: 361 FHVYPYLDSVVHEKTKCLLSLFRDIGHHLIHNNKIGGINSLLSKQAVSKNLKEDKPVKEK 420
FHVYPYLDSVVHEKTKCLLSLFRDIGHHLIHNNKIGGINSLLSKQAVSKNLKEDKPVKEK
Sbjct: 361 FHVYPYLDSVVHEKTKCLLSLFRDIGHHLIHNNKIGGINSLLSKQAVSKNLKEDKPVKEK 420
Query: 421 DIDGRPRPGDVQAPSIKSQSSDTPLEGEPPLSHNPEGQQYVEAGTYIVLEIQLDKALVPK 480
DIDGRPRPGDVQAPSIKSQSSDTPLEGEPPLSHNPEGQQYVEAGTYIVLEIQLDKALVPK
Sbjct: 421 DIDGRPRPGDVQAPSIKSQSSDTPLEGEPPLSHNPEGQQYVEAGTYIVLEIQLDKALVPK 480
Query: 481 RMPEELARRVKEMIPPRPPLTRRTGGAQKAMSDYHIQIKNISRAILDEYYRMFGKQVAKL 540
RMPEELARRVKEMIPPRPPLTRRTGGAQKAMSDYHIQIKNISRAILDEYYRMFGKQVAKL
Sbjct: 481 RMPEELARRVKEMIPPRPPLTRRTGGAQKAMSDYHIQIKNISRAILDEYYRMFGKQVAKL 540
Query: 541 ESDMDSETLEEQKCQLSYELNCSGKYFAFKEQLKHAVVKIVRDKYLKTTSFESQEELQTF 600
ESDMDSETLEEQKCQLSYELNCSGKYFAFKEQLKHAVVKIVRDKYLKTTSFESQEELQTF
Sbjct: 541 ESDMDSETLEEQKCQLSYELNCSGKYFAFKEQLKHAVVKIVRDKYLKTTSFESQEELQTF 600
Query: 601 ISELYVFLVDQMHVALNQTMPDDVQGTVATIYTSSEQLQLFAFEAEVNENFEMAAAYYKE 660
ISELYVFLVDQMHVALNQTMPDDVQGTVATIYTSSEQLQLFAFEAEVNENFEMAAAYYKE
Sbjct: 601 ISELYVFLVDQMHVALNQTMPDDVQGTVATIYTSSEQLQLFAFEAEVNENFEMAAAYYKE 660
Query: 661 RLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYE 720
RLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYE
Sbjct: 661 RLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYE 720
Query: 721 QAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEASKQLQARMLQAQVTKQK 780
QAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEASKQLQARMLQAQVTKQK
Sbjct: 721 QAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEASKQLQARMLQAQVTKQK 780
Query: 781 STGVEDTEERGKRESSLGPWGITNGSATAIKVEAPAGPGAALSILDKFLEESSKLQSDSQ 840
STGVEDTEERGKRESSLGPWGITNGSATAIKVEAPAGPGAALSILDKFLEESSKLQSDSQ
Sbjct: 781 STGVEDTEERGKRESSLGPWGITNGSATAIKVEAPAGPGAALSILDKFLEESSKLQSDSQ 840
Query: 841 EPILTTQTWDPSISQKPSNTFIKEIPTKKEASKCQDSSALLHPGLHYGVSQTTTIFMETI 900
EPILTTQTWDPSISQKPSNTFIKEIPTKKEASKCQDSSALLHPGLHYGVSQTTTIFMETI
Sbjct: 841 EPILTTQTWDPSISQKPSNTFIKEIPTKKEASKCQDSSALLHPGLHYGVSQTTTIFMETI 900
Query: 901 HFLMKVKAVQYVHRVLAHELLCPQGGPSCEYYLVLAQTHILKKNFAKAEEYLQQAAQMDY 960
HFLMKVKAVQYVHRVLAHELLCPQGGPSCEYYLVLAQTHILKKNFAKAEEYLQQAAQMDY
Sbjct: 901 HFLMKVKAVQYVHRVLAHELLCPQGGPSCEYYLVLAQTHILKKNFAKAEEYLQQAAQMDY 960
Query: 961 LNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAK 1020
LNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAK
Sbjct: 961 LNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAK 1020
Query: 1021 KTYMQACKRSPSCLTWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKV 1080
KTYMQACKRSPSCLTWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKV
Sbjct: 1021 KTYMQACKRSPSCLTWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKV 1080
Query: 1081 GRQLEAEQAYKYMIKLKLKDEALLAEIHTLQETVGFGNPSF 1121
GRQLEAEQAYKYMIKLKLKDEALLAEIHTLQETVGFGNPSF
Sbjct: 1081 GRQLEAEQAYKYMIKLKLKDEALLAEIHTLQETVGFGNPSF 1121
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 50.1 bits (118), Expect = 1e-05
Identities = 47/185 (25%), Positives = 79/185 (42%), Gaps = 15/185 (8%)
Query: 565 KYFAFKEQLKHAV-VKIVRDKYLKTTSF-ESQEELQTFISELYVFLVDQMHVALNQTMPD 622
+Y AF Q + V ++ LKT SF E QE+L +++ L + + +L +
Sbjct: 1624 QYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFER 1683
Query: 623 DVQGTVATIYTSSEQLQLFAFEAEV---NENFEMAAAYYKERLVREPQNLDHWLDYGAFC 679
VQ +E L++F A++ +E F+ A Y L R Q W+ YGAF
Sbjct: 1684 AVQ--------YNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFL 1735
Query: 680 LLTEDNIKAQECFQKALSL--NQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNV 737
L + Q+AL ++ H+ + L L + E+A+ FE+ P
Sbjct: 1736 LRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRT 1795
Query: 738 VAWTL 742
W++
Sbjct: 1796 DVWSV 1800
Score = 31.6 bits (70), Expect = 4.4
Identities = 38/185 (20%), Positives = 71/185 (38%), Gaps = 11/185 (5%)
Query: 839 SQEPILTTQTWDPSIS-QKPSNTFIKEIPTKKEASKCQDSSALLHPGLHYGVSQTTTIFM 897
SQE + T+ ++ ++ +P F+ ++ K Q++ L + L Q +++
Sbjct: 1673 SQESL--TKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKR-FRQEKAVWI 1729
Query: 898 ETIHFLMKVKAVQYVHRVLAHELLCPQGGPSCEYYLVLAQTHILKKNFAKAEEYLQQAAQ 957
+ FL++ HRVL L C + AQ + +A+ +
Sbjct: 1730 KYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLS 1789
Query: 958 MDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYE 1017
+VW + + G+ + + +ER I + M F F R YL +YE
Sbjct: 1790 TYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKR----YL---DYE 1842
Query: 1018 KAKKT 1022
K T
Sbjct: 1843 KQHGT 1847
>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
sapiens]
Length = 833
Score = 48.1 bits (113), Expect = 5e-05
Identities = 42/174 (24%), Positives = 76/174 (43%), Gaps = 4/174 (2%)
Query: 928 SCEYYLVLAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYE 987
S E +A + L +N ++A E+L Q + +P V G LY G+ S+A Y
Sbjct: 560 SAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYY 619
Query: 988 RTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPSCLTWLGLGIACYRLE 1047
+ + E + LG Y++ + +EKA + + +A P+ + W + +C+R
Sbjct: 620 ESYRYFPCNIE---VIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRS 676
Query: 1048 -ELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKD 1100
+A D + + N E +L +C +G + E A K K+K+
Sbjct: 677 GNYQKALDTYKDTHRKFPENVECLRFLVRLCTDLGLKDAQEYARKLKRLEKMKE 730
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/188 (21%), Positives = 73/188 (38%), Gaps = 38/188 (20%)
Query: 935 LAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVV 994
L+ + + K+FA+A Y A D NP KG+ F +G
Sbjct: 465 LSALYYMGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANG----------------- 507
Query: 995 DASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPSCLTWL-GLGIACYRLEELTEAE 1053
+YEKA + Y +A + SC L +G+ +L L EA
Sbjct: 508 --------------------DYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEAL 547
Query: 1054 DALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKDEALLAEIHTLQET 1113
D + +A+ +AEV +A + + +A + ++ + D +L+++ L +
Sbjct: 548 DCFLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDR 607
Query: 1114 VGFGNPSF 1121
G + +F
Sbjct: 608 EGDKSQAF 615
Score = 31.2 bits (69), Expect = 5.8
Identities = 25/116 (21%), Positives = 50/116 (43%)
Query: 648 NENFEMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLL 707
N ++E AA +YKE L + + + G +A +CF K ++ ++ L
Sbjct: 506 NGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLY 565
Query: 708 LCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEA 763
+ L+EN QA + + PT+ + LG Y+ + + + ++E+
Sbjct: 566 QIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYES 621
>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
sapiens]
Length = 824
Score = 48.1 bits (113), Expect = 5e-05
Identities = 42/174 (24%), Positives = 76/174 (43%), Gaps = 4/174 (2%)
Query: 928 SCEYYLVLAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYE 987
S E +A + L +N ++A E+L Q + +P V G LY G+ S+A Y
Sbjct: 551 SAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYY 610
Query: 988 RTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPSCLTWLGLGIACYRLE 1047
+ + E + LG Y++ + +EKA + + +A P+ + W + +C+R
Sbjct: 611 ESYRYFPCNIE---VIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRS 667
Query: 1048 -ELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKD 1100
+A D + + N E +L +C +G + E A K K+K+
Sbjct: 668 GNYQKALDTYKDTHRKFPENVECLRFLVRLCTDLGLKDAQEYARKLKRLEKMKE 721
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/188 (21%), Positives = 73/188 (38%), Gaps = 38/188 (20%)
Query: 935 LAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVV 994
L+ + + K+FA+A Y A D NP KG+ F +G
Sbjct: 456 LSALYYMGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANG----------------- 498
Query: 995 DASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPSCLTWL-GLGIACYRLEELTEAE 1053
+YEKA + Y +A + SC L +G+ +L L EA
Sbjct: 499 --------------------DYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEAL 538
Query: 1054 DALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKDEALLAEIHTLQET 1113
D + +A+ +AEV +A + + +A + ++ + D +L+++ L +
Sbjct: 539 DCFLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDR 598
Query: 1114 VGFGNPSF 1121
G + +F
Sbjct: 599 EGDKSQAF 606
Score = 31.2 bits (69), Expect = 5.8
Identities = 25/116 (21%), Positives = 50/116 (43%)
Query: 648 NENFEMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLL 707
N ++E AA +YKE L + + + G +A +CF K ++ ++ L
Sbjct: 497 NGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLY 556
Query: 708 LCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEA 763
+ L+EN QA + + PT+ + LG Y+ + + + ++E+
Sbjct: 557 QIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYES 612
>gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens]
Length = 843
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Query: 969 KGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACK 1028
K L+ + E C+ER++ ++ ++ ++ LG YL ++Y+ + K + +
Sbjct: 533 KALLHLRNKEFQECVECFERSVK--INPMQLG-VWFSLGCAYLALEDYQGSAKAFQRCVT 589
Query: 1029 RSP-SCLTWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAE 1087
P + W L + RL++ +A L EA N + ++W L VG EA
Sbjct: 590 LEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAI 649
Query: 1088 QAYKYMIKL--KLKDEALL 1104
+AY ++ L K KD +L
Sbjct: 650 KAYHRLLDLRDKYKDVQVL 668
Score = 37.7 bits (86), Expect = 0.062
Identities = 20/76 (26%), Positives = 33/76 (43%)
Query: 690 ECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEI 749
ECF++++ +N + G + LE+Y+ + F+ LEP N AW L Y
Sbjct: 548 ECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIR 607
Query: 750 QNNDIRMEMAFHEASK 765
++ EA K
Sbjct: 608 LKQKVKAFRTLQEALK 623
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 44.3 bits (103), Expect = 7e-04
Identities = 38/177 (21%), Positives = 74/177 (41%), Gaps = 14/177 (7%)
Query: 932 YLVLAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTIS 991
YL L K NF +A ++ ++A Q++ +P+ W L G+L+ + +ER +
Sbjct: 534 YLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILK 593
Query: 992 FVVDASEMHFIFLRLGLIYL------------EEKEYEKAKKTYMQACKRSPSCL-TWLG 1038
S+ + L LG ++L E++ ++A Y Q + L G
Sbjct: 594 QPSTQSDT-YSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANG 652
Query: 1039 LGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIK 1095
+G EA D ++ ++VW LA + ++ + + A Q Y+ ++
Sbjct: 653 IGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLR 709
Score = 33.9 bits (76), Expect = 0.89
Identities = 35/168 (20%), Positives = 69/168 (41%), Gaps = 12/168 (7%)
Query: 613 HVALNQTMPDDVQGTVATIYTSSEQLQLFAFEAEVNENFEMAAAYYKERLVREPQNLD-H 671
H+AL+ +V+ A E A V E+++ A YY + +
Sbjct: 290 HLALHAFHNTEVEAMQA------ESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLP 343
Query: 672 WLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEI---FFED 728
+ G + D A +CF+K L ++ ++ + G L E+ E+ +I +
Sbjct: 344 FFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKK 403
Query: 729 ATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEASKQLQARMLQAQV 776
T P +V AW + L ++ DI+ ++ + + ++ +QA V
Sbjct: 404 VTEQYPDDVEAW--IELAQILEQTDIQGALSAYGTATRILQEKVQADV 449
Score = 31.6 bits (70), Expect = 4.4
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 14/101 (13%)
Query: 978 NHSEAKACYERTISFVVDASEMHFIF------------LRLGLIYLEEKEYEKAKKTYMQ 1025
NH +AC+ +D ++ F F L I +K+Y A Y +
Sbjct: 129 NHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKK 188
Query: 1026 ACKRSPSC--LTWLGLGIACYRLEELTEAEDALSEANALNN 1064
A + +P C LG+G +L +L +A A S A LN+
Sbjct: 189 ALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNS 229
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapiens]
Length = 830
Score = 40.4 bits (93), Expect = 0.009
Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Query: 958 MDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYE 1017
MD +P W G+ + L H A ++R I VD + + + LG ++ +E +
Sbjct: 568 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ--VDPNYA-YAYTLLGHEFVLTEELD 624
Query: 1018 KAKKTYMQACKRSPSCLT-WLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALV 1076
KA + A + +P W GLG+ Y+ E+ + AE +A +N ++ + ++ +V
Sbjct: 625 KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVV 684
Score = 40.0 bits (92), Expect = 0.012
Identities = 30/128 (23%), Positives = 65/128 (50%), Gaps = 6/128 (4%)
Query: 941 LKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMH 1000
L++ A ++ Q+A Q+D + L GH + L+ +A AC+ I + H
Sbjct: 585 LQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR----VNPRH 640
Query: 1001 F-IFLRLGLIYLEEKEYEKAKKTYMQACKRSP-SCLTWLGLGIACYRLEELTEAEDALSE 1058
+ + LG+IY +++++ A+ + +A +P S + +G+ + L++ +A D L++
Sbjct: 641 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNK 700
Query: 1059 ANALNNYN 1066
A ++ N
Sbjct: 701 AIVIDPKN 708
Score = 38.9 bits (89), Expect = 0.028
Identities = 26/92 (28%), Positives = 44/92 (47%)
Query: 672 WLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATC 731
W G L ++ A + FQ+A+ ++ ++ ++ L G VL E ++A F +A
Sbjct: 576 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 635
Query: 732 LEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEA 763
+ P + AW LG+ Y Q EM F +A
Sbjct: 636 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA 667
Score = 37.4 bits (85), Expect = 0.080
Identities = 22/94 (23%), Positives = 46/94 (48%)
Query: 652 EMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGV 711
++A +++ + +P + G +LTE+ KA CF+ A+ +N H ++ G+
Sbjct: 590 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 649
Query: 712 LAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGL 745
+ E + AE+ F+ A + P + V +G+
Sbjct: 650 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 683
Score = 36.2 bits (82), Expect = 0.18
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 640 LFAFEAEVNENFEMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLN 699
L E + E + A A ++ + P++ + W G E A+ FQKAL +N
Sbjct: 612 LLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN 671
Query: 700 QSHIHSLLLC--GVLAVLLENYEQAEIFFEDATCLEPTN 736
S+LLC GV+ L+ E+A A ++P N
Sbjct: 672 PQ--SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKN 708
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapiens]
Length = 824
Score = 40.4 bits (93), Expect = 0.009
Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Query: 958 MDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYE 1017
MD +P W G+ + L H A ++R I VD + + + LG ++ +E +
Sbjct: 562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ--VDPNYA-YAYTLLGHEFVLTEELD 618
Query: 1018 KAKKTYMQACKRSPSCLT-WLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALV 1076
KA + A + +P W GLG+ Y+ E+ + AE +A +N ++ + ++ +V
Sbjct: 619 KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVV 678
Score = 40.0 bits (92), Expect = 0.012
Identities = 30/128 (23%), Positives = 65/128 (50%), Gaps = 6/128 (4%)
Query: 941 LKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMH 1000
L++ A ++ Q+A Q+D + L GH + L+ +A AC+ I + H
Sbjct: 579 LQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR----VNPRH 634
Query: 1001 F-IFLRLGLIYLEEKEYEKAKKTYMQACKRSP-SCLTWLGLGIACYRLEELTEAEDALSE 1058
+ + LG+IY +++++ A+ + +A +P S + +G+ + L++ +A D L++
Sbjct: 635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNK 694
Query: 1059 ANALNNYN 1066
A ++ N
Sbjct: 695 AIVIDPKN 702
Score = 38.9 bits (89), Expect = 0.028
Identities = 26/92 (28%), Positives = 44/92 (47%)
Query: 672 WLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATC 731
W G L ++ A + FQ+A+ ++ ++ ++ L G VL E ++A F +A
Sbjct: 570 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 629
Query: 732 LEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEA 763
+ P + AW LG+ Y Q EM F +A
Sbjct: 630 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA 661
Score = 37.4 bits (85), Expect = 0.080
Identities = 22/94 (23%), Positives = 46/94 (48%)
Query: 652 EMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGV 711
++A +++ + +P + G +LTE+ KA CF+ A+ +N H ++ G+
Sbjct: 584 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 643
Query: 712 LAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGL 745
+ E + AE+ F+ A + P + V +G+
Sbjct: 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677
Score = 36.2 bits (82), Expect = 0.18
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 640 LFAFEAEVNENFEMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLN 699
L E + E + A A ++ + P++ + W G E A+ FQKAL +N
Sbjct: 606 LLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN 665
Query: 700 QSHIHSLLLC--GVLAVLLENYEQAEIFFEDATCLEPTN 736
S+LLC GV+ L+ E+A A ++P N
Sbjct: 666 PQ--SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKN 702
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 40.4 bits (93), Expect = 0.009
Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 658 YKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLE 717
+KE L ++ +D + G + A E FQKAL LNQ+H+ +L L G++
Sbjct: 253 FKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHG 312
Query: 718 NYEQAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEASKQLQARMLQAQVT 777
+ ++A F+ LEP N V + GL + F+E K ML +
Sbjct: 313 SLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQ-------FYEGIKAQTKVMLNDPLP 365
Query: 778 KQKST 782
QK++
Sbjct: 366 GQKAS 370
Score = 39.7 bits (91), Expect = 0.016
Identities = 60/291 (20%), Positives = 110/291 (37%), Gaps = 12/291 (4%)
Query: 785 EDTEERGKRESSLGPWGITNGSAT-AIKVEAPAGPGAALSILDKFLEESSKLQSDSQEPI 843
++ + R ++E+ G G + S + A G + L+ D E DS
Sbjct: 57 QELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECGESSFLNFHDSDCEPKGSSPCDS---- 112
Query: 844 LTTQTWDPSISQKPSNTFIKEIPTKKEASKCQDSSALLHPGLHYGVSQTTTIFMETIHFL 903
L + + +SQ S K P + + A+ + + G+ T+ L
Sbjct: 113 LLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTM--L 170
Query: 904 MKVKAVQYVHRVLAHELLCPQGGPSCEYYLVLAQTHILKKNFAKAEEYLQQAAQMDYLNP 963
+ + ++ + Q PS Y + + +++A A E QQ+ +++ P
Sbjct: 171 QILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQP 230
Query: 964 NVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTY 1023
KG +F G EA ++ + VD + + LG Y E +E A +++
Sbjct: 231 IAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFID---AYKSLGQAYRELGNFEAATESF 287
Query: 1024 MQACKRSPSCLTWLGL-GIACYRLEELTEAEDALSEANALNNYNAEVWAYL 1073
+A + + + L L G+ Y L EA L YN EV Y+
Sbjct: 288 QKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYN-EVCQYM 337
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 40.4 bits (93), Expect = 0.009
Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 658 YKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLE 717
+KE L ++ +D + G + A E FQKAL LNQ+H+ +L L G++
Sbjct: 306 FKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHG 365
Query: 718 NYEQAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEASKQLQARMLQAQVT 777
+ ++A F+ LEP N V + GL + F+E K ML +
Sbjct: 366 SLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQ-------FYEGIKAQTKVMLNDPLP 418
Query: 778 KQKST 782
QK++
Sbjct: 419 GQKAS 423
Score = 38.5 bits (88), Expect = 0.036
Identities = 37/148 (25%), Positives = 62/148 (41%), Gaps = 5/148 (3%)
Query: 927 PSCEYYLVLAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACY 986
PS Y + + +++A A E QQ+ +++ P KG +F G EA +
Sbjct: 247 PSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESF 306
Query: 987 ERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPSCLTWLGL-GIACYR 1045
+ + VD + + LG Y E +E A +++ +A + + + L L G+ Y
Sbjct: 307 KEALKQKVDFID---AYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYH 363
Query: 1046 LEELTEAEDALSEANALNNYNAEVWAYL 1073
L EA L YN EV Y+
Sbjct: 364 HGSLQEALKNFKRCLQLEPYN-EVCQYM 390
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 40.0 bits (92), Expect = 0.012
Identities = 57/241 (23%), Positives = 92/241 (38%), Gaps = 46/241 (19%)
Query: 897 METIHFLMKVKAVQYVHRVLAHELLCPQGGPSCEYYLVLAQTHILKKNFAKAEEYLQQAA 956
M+T L+ V++++ LAH L C E V+ + L+ KA Y Q+A
Sbjct: 300 MDTFSNLLYVRSMKSELSYLAHNL-CEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRAL 358
Query: 957 QMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISF-------------VVDASEMHF-- 1001
+++ W L GH Y N S A Y I + +M F
Sbjct: 359 KLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYC 418
Query: 1002 ----------------IFLRLGLIYLEEKEYEKAKKTYMQACKRSPSCLTWLGLGIACYR 1045
+ + LG Y + + +AKK Y +A + + + L
Sbjct: 419 LYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRA--YAVGDVEKMALVKLAKL 476
Query: 1046 LEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYM----IKLKLKDE 1101
E+LTE+E A A Y ++++ C ++ LE A++Y+ K KL DE
Sbjct: 477 HEQLTESEQA---AQCYIKYIQDIYS-----CGEIVEHLEESTAFRYLAQYYFKCKLWDE 528
Query: 1102 A 1102
A
Sbjct: 529 A 529
Score = 32.7 bits (73), Expect = 2.0
Identities = 20/113 (17%), Positives = 49/113 (43%), Gaps = 1/113 (0%)
Query: 650 NFEMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLC 709
+ + A + + E ++P +++ + + + +++ + + +
Sbjct: 278 DIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVI 337
Query: 710 GVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLG-LYYEIQNNDIRMEMAFH 761
G L +E+A ++F+ A L P + AWTL+G Y E++N ++ H
Sbjct: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRH 390
Score = 32.3 bits (72), Expect = 2.6
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 18/131 (13%)
Query: 676 GAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPT 735
G + L + KA FQ+AL LN ++ + L G + ++N A + A +
Sbjct: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397
Query: 736 NVVAWTLLGLYYEI-----------------QNNDIRMEMAFHEASKQLQARMLQAQVTK 778
+ AW LG YEI + ND RM +A E ++L ++++A+
Sbjct: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLN-QLVEAKKCY 456
Query: 779 QKSTGVEDTEE 789
++ V D E+
Sbjct: 457 WRAYAVGDVEK 467
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 38.5 bits (88), Expect = 0.036
Identities = 52/216 (24%), Positives = 96/216 (44%), Gaps = 20/216 (9%)
Query: 695 ALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEI---QN 751
A++LN+S+ + G L+ E+A+ +E LEP N A L + +
Sbjct: 34 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 93
Query: 752 NDIRMEMAFHEASKQLQARMLQAQVTKQKSTGVEDTE----ERGKRESSLGPW--GITNG 805
N E S + + + ++AQ KQ++ +D + GK E ++ + GI
Sbjct: 94 NSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAAD 153
Query: 806 SATAIKVEAPAGPGAALSILDKFLEESSKLQSDSQEPILTTQTWDPSISQK-PSNTFIKE 864
A A+ PA A + K+ EE+ K D + IL ++ + +++ + TF+ +
Sbjct: 154 GANAL---LPANRAMAYLKIQKY-EEAEK---DCTQAILLDGSYSKAFARRGTARTFLGK 206
Query: 865 IPTKKEASKCQDSSALLHPGLHYGVSQTTTIFMETI 900
+ EA + ++ LL PG V++ + I E I
Sbjct: 207 L---NEAKQDFETVLLLEPGNKQAVTELSKIKKELI 239
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 38.5 bits (88), Expect = 0.036
Identities = 52/216 (24%), Positives = 96/216 (44%), Gaps = 20/216 (9%)
Query: 695 ALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEI---QN 751
A++LN+S+ + G L+ E+A+ +E LEP N A L + +
Sbjct: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
Query: 752 NDIRMEMAFHEASKQLQARMLQAQVTKQKSTGVEDTE----ERGKRESSLGPW--GITNG 805
N E S + + + ++AQ KQ++ +D + GK E ++ + GI
Sbjct: 253 NSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAAD 312
Query: 806 SATAIKVEAPAGPGAALSILDKFLEESSKLQSDSQEPILTTQTWDPSISQK-PSNTFIKE 864
A A+ PA A + K+ EE+ K D + IL ++ + +++ + TF+ +
Sbjct: 313 GANAL---LPANRAMAYLKIQKY-EEAEK---DCTQAILLDGSYSKAFARRGTARTFLGK 365
Query: 865 IPTKKEASKCQDSSALLHPGLHYGVSQTTTIFMETI 900
+ EA + ++ LL PG V++ + I E I
Sbjct: 366 L---NEAKQDFETVLLLEPGNKQAVTELSKIKKELI 398
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 38.1 bits (87), Expect = 0.047
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 5/162 (3%)
Query: 947 KAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRL 1006
KA + QQA ++ + G LY G +S A+ Y+R + A I L
Sbjct: 526 KAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAE----ILSPL 581
Query: 1007 GLIYLEEKEYEKAKKTYMQACKRSPSCLTW-LGLGIACYRLEELTEAEDALSEANALNNY 1065
G +Y YE+A + Y +A PS L L + + EAE + +
Sbjct: 582 GALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETG 641
Query: 1066 NAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKDEALLAEI 1107
E + L+ + K +A A ++LK KD +++E+
Sbjct: 642 CLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISEL 683
Score = 35.4 bits (80), Expect = 0.31
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 981 EAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPS-CLTWLGL 1039
EA+ Y+ I D+S++H + G+ ++ EKA Y QA K SPS + + L
Sbjct: 492 EAEEIYQTGIKNCPDSSDLHNNY---GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNL 548
Query: 1040 GIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYK 1091
G L E + AE+ A + + AE+ + L + GR EA Q Y+
Sbjct: 549 GRLYRSLGENSMAEEWYKRALQV-AHKAEILSPLGALYYNTGRYEEALQIYQ 599
Score = 34.3 bits (77), Expect = 0.68
Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Query: 649 ENFEMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLL 708
E F+ A Y+ + P + D +YG F + T KA +Q+A+ L+ SH +++
Sbjct: 488 ERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVN 547
Query: 709 CGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEAS---- 764
G L L AE +++ A + + L LYY + +++ + EA+
Sbjct: 548 LGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQI-YQEAAALQP 606
Query: 765 KQLQARMLQAQV 776
Q + R+ AQV
Sbjct: 607 SQRELRLALAQV 618
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 37.7 bits (86), Expect = 0.062
Identities = 39/189 (20%), Positives = 82/189 (43%), Gaps = 22/189 (11%)
Query: 570 KEQLKHAVVKIVRDKYLKT-TSFESQEELQTFISEL---YVFLVDQMHVALNQT------ 619
K++L +A+++ + D+ S ++QE L+ I L + V+ +AL QT
Sbjct: 4 KKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFE 63
Query: 620 -------MPDDVQGTVATIYTSSEQLQLFAFEAEVNE-----NFEMAAAYYKERLVREPQ 667
MP D++ T + + + + E NE NFE A +Y + + P
Sbjct: 64 AAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPA 123
Query: 668 NLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFE 727
N ++ + A + A + ++A+ ++ ++ + G+ L + +A +++
Sbjct: 124 NAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYK 183
Query: 728 DATCLEPTN 736
A L+P N
Sbjct: 184 KALELDPDN 192
>gi|118402578 anaphase-promoting complex, subunit 6 [Homo sapiens]
Length = 620
Score = 37.4 bits (85), Expect = 0.080
Identities = 42/195 (21%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 931 YYLVLAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTI 990
YYL++ + A YL +A ++ W GH + + H +A A Y
Sbjct: 308 YYLMVGHKN------EHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAA 361
Query: 991 SFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSP-SCLTWLGLGIACYRLEEL 1049
+ H L +GL Y + A++ + QA +P +G+ ++ E
Sbjct: 362 QLM---KGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEW 418
Query: 1050 TEAE----DALSEANAL-NNYNAEVWA----YLALVCLKVGRQLEAEQAYKYMIKLKLKD 1100
AE DAL + A+ N + W L VC K+ + EA ++ + L ++
Sbjct: 419 KTAEKWFLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQN 478
Query: 1101 EALLAEIHTLQETVG 1115
+ + I + +G
Sbjct: 479 ASTYSAIGYIHSLMG 493
>gi|118402580 anaphase-promoting complex, subunit 6 [Homo sapiens]
Length = 620
Score = 37.4 bits (85), Expect = 0.080
Identities = 42/195 (21%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 931 YYLVLAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTI 990
YYL++ + A YL +A ++ W GH + + H +A A Y
Sbjct: 308 YYLMVGHKN------EHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAA 361
Query: 991 SFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSP-SCLTWLGLGIACYRLEEL 1049
+ H L +GL Y + A++ + QA +P +G+ ++ E
Sbjct: 362 QLM---KGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEW 418
Query: 1050 TEAE----DALSEANAL-NNYNAEVWA----YLALVCLKVGRQLEAEQAYKYMIKLKLKD 1100
AE DAL + A+ N + W L VC K+ + EA ++ + L ++
Sbjct: 419 KTAEKWFLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQN 478
Query: 1101 EALLAEIHTLQETVG 1115
+ + I + +G
Sbjct: 479 ASTYSAIGYIHSLMG 493
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 37.0 bits (84), Expect = 0.10
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 20/211 (9%)
Query: 695 ALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEI---QN 751
A++LN+S+ + G L+ E+A+ +E LEP N A L + +
Sbjct: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
Query: 752 NDIRMEMAFHEASKQLQARMLQAQVTKQKSTGVEDTE----ERGKRESSLGPW--GITNG 805
N E S + + + ++AQ KQ++ +D + GK E ++ + GI
Sbjct: 253 NSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAAD 312
Query: 806 SATAIKVEAPAGPGAALSILDKFLEESSKLQSDSQEPILTTQTWDPSISQK-PSNTFIKE 864
A A+ PA A + K+ EE+ K D + IL ++ + +++ + TF+ +
Sbjct: 313 GANAL---LPANRAMAYLKIQKY-EEAEK---DCTQAILLDGSYSKAFARRGTARTFLGK 365
Query: 865 IPTKKEASKCQDSSALLHPGLHYGVSQTTTI 895
+ EA + ++ LL PG V++ + I
Sbjct: 366 L---NEAKQDFETVLLLEPGNKQAVTELSKI 393
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 36.6 bits (83), Expect = 0.14
Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 953 QQAAQMDY-----LNPN---VWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFL 1004
+Q A DY LNP + G++YF S+A + + + F E ++ +
Sbjct: 1458 KQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKF---DPENEYVLM 1514
Query: 1005 RLGLIYLEEKEYEKAKKTYMQACKRSPS-CLTWLGLGIACYRLEELTEAEDALSEANALN 1063
+ K+YE+AK+ + + P + Y L++ AE+ L++A +L
Sbjct: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLK 1574
Query: 1064 NYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLK 1097
+A V+ + A V K+G EA Y + L+
Sbjct: 1575 PNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 36.6 bits (83), Expect = 0.14
Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 953 QQAAQMDY-----LNPN---VWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFL 1004
+Q A DY LNP + G++YF S+A + + + F E ++ +
Sbjct: 1458 KQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKF---DPENEYVLM 1514
Query: 1005 RLGLIYLEEKEYEKAKKTYMQACKRSPS-CLTWLGLGIACYRLEELTEAEDALSEANALN 1063
+ K+YE+AK+ + + P + Y L++ AE+ L++A +L
Sbjct: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLK 1574
Query: 1064 NYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLK 1097
+A V+ + A V K+G EA Y + L+
Sbjct: 1575 PNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 36.6 bits (83), Expect = 0.14
Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 953 QQAAQMDY-----LNPN---VWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFL 1004
+Q A DY LNP + G++YF S+A + + + F E ++ +
Sbjct: 1458 KQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKF---DPENEYVLM 1514
Query: 1005 RLGLIYLEEKEYEKAKKTYMQACKRSPS-CLTWLGLGIACYRLEELTEAEDALSEANALN 1063
+ K+YE+AK+ + + P + Y L++ AE+ L++A +L
Sbjct: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLK 1574
Query: 1064 NYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLK 1097
+A V+ + A V K+G EA Y + L+
Sbjct: 1575 PNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 36.2 bits (82), Expect = 0.18
Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 21/171 (12%)
Query: 942 KKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISF----VVDAS 997
KK+F A ++ +A ++D N + +YF G++++ + E+ I D
Sbjct: 238 KKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYR 297
Query: 998 EMHFIFLRLGLIYLEEKEYEKAKKTYMQ--ACKRSPSCLTWLGLGIACYRLEELTEAEDA 1055
++ + R+G Y +E++Y+ A Y + A R+P L C + E++ + ++
Sbjct: 298 QIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLK------KCQQAEKILKEQER 351
Query: 1056 LSEAN---ALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKDEAL 1103
L+ N AL N C + G +A + Y IK KD L
Sbjct: 352 LAYINPDLALEEKNK------GNECFQKGDYPQAMKHYTEAIKRNPKDAKL 396
>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
Length = 1564
Score = 36.2 bits (82), Expect = 0.18
Identities = 23/74 (31%), Positives = 36/74 (48%)
Query: 688 AQECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYY 747
AQ CF K++ Q + + GVL + EN EQA F+ A L+P+ ++ W L
Sbjct: 846 AQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIA 905
Query: 748 EIQNNDIRMEMAFH 761
E + M++ H
Sbjct: 906 EAVGSYDTMDLFRH 919
Score = 35.8 bits (81), Expect = 0.23
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 6/85 (7%)
Query: 687 KAQECFQKALSLNQSHIHSLLLCGVLAVL--LENYEQAEIFFEDATCLEPTNVVAWTLLG 744
K+ C +KA+ L+ ++ GV+A + NY A+ F + E N VAWT LG
Sbjct: 809 KSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLG 868
Query: 745 LYYEIQNNDIRMEMAFHEASKQLQA 769
+ Y N +E A HEA K Q+
Sbjct: 869 VLYLTNEN---IEQA-HEAFKMAQS 889
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/57 (31%), Positives = 31/57 (54%)
Query: 696 LSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEIQNN 752
L +++ ++ + GV A LE +QA+ ++ A LEP ++AW L YE N+
Sbjct: 33 LKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYNH 89
Score = 32.7 bits (73), Expect = 2.0
Identities = 36/181 (19%), Positives = 73/181 (40%), Gaps = 17/181 (9%)
Query: 940 ILKKN---------FAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTI 990
+LKKN + +A + + + L N + HL N ++ K E+++
Sbjct: 752 VLKKNELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSL 811
Query: 991 SFVVDA----SEMHFIFLRLGLI--YLEEKEYEKAKKTYMQACKRSP-SCLTWLGLGIAC 1043
+ A S H + LG++ Y Y A+ ++++ + + + W LG+
Sbjct: 812 HCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLY 871
Query: 1044 YRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKDEAL 1103
E + +A +A A +L+ W AL+ VG + +++ +L + E
Sbjct: 872 LTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVG-SYDTMDLFRHTTELNMHTEGA 930
Query: 1104 L 1104
L
Sbjct: 931 L 931
Score = 32.0 bits (71), Expect = 3.4
Identities = 18/76 (23%), Positives = 38/76 (50%)
Query: 650 NFEMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLC 709
N+ +A + + + E N W + G L E+ +A E F+ A SL+ S++ +
Sbjct: 842 NYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQ 901
Query: 710 GVLAVLLENYEQAEIF 725
++A + +Y+ ++F
Sbjct: 902 ALIAEAVGSYDTMDLF 917
Score = 30.8 bits (68), Expect = 7.5
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 1006 LGLIYLEEKEYEKAKKTYMQACKRSPSCLT-WLGLGIACYRLEELTEAEDALSEA 1059
LG+ L++K+YE A + + K SP C + W L A ++ EA + S+A
Sbjct: 278 LGIKALQDKKYEDAVRNLTEGLKESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQA 332
>gi|4557719 DNA ligase I [Homo sapiens]
Length = 919
Score = 35.8 bits (81), Expect = 0.23
Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 51 SPEGSAKYNFTSSFEFNPEGGITSDDLAHKPV-FLTVTEVLPKE-----------KKQKE 98
SPE +A + TS + +P G I A K + T+ EVL ++ K+++E
Sbjct: 98 SPENNASLSDTSPMDSSPSG-IPKRRTARKQLPKRTIQEVLEEQSEDEDREAKRKKEEEE 156
Query: 99 EKTLILGQAVVDLLPLLEGQSSFQTTVPLHPVQGSPLETPRSSAKQCSLEVK 150
E+T ++ EG+ Q T P P++ S ETP S + + K
Sbjct: 157 EETPKESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAETPTESVSEPEVATK 208
>gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sapiens]
Length = 639
Score = 35.4 bits (80), Expect = 0.31
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 945 FAKAEEYLQQAAQMD--YLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFI 1002
F + +E A ++D ++P+V G L+ LSG + +A C+ +S + +
Sbjct: 468 FLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSV---RPNDYLL 524
Query: 1003 FLRLGLIYLEEKEYEKAKKTYMQACKRSPSCL-TWLGLGIACYRLEELTEAEDALSEA 1059
+ +LG + E+A Y +A + P + + LGI+C L EA + EA
Sbjct: 525 WNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEA 582
>gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sapiens]
Length = 639
Score = 35.4 bits (80), Expect = 0.31
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 945 FAKAEEYLQQAAQMD--YLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFI 1002
F + +E A ++D ++P+V G L+ LSG + +A C+ +S + +
Sbjct: 468 FLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSV---RPNDYLL 524
Query: 1003 FLRLGLIYLEEKEYEKAKKTYMQACKRSPSCL-TWLGLGIACYRLEELTEAEDALSEA 1059
+ +LG + E+A Y +A + P + + LGI+C L EA + EA
Sbjct: 525 WNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEA 582
>gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sapiens]
Length = 602
Score = 35.4 bits (80), Expect = 0.31
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 945 FAKAEEYLQQAAQMD--YLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFI 1002
F + +E A ++D ++P+V G L+ LSG + +A C+ +S + +
Sbjct: 431 FLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSV---RPNDYLL 487
Query: 1003 FLRLGLIYLEEKEYEKAKKTYMQACKRSPSCL-TWLGLGIACYRLEELTEAEDALSEA 1059
+ +LG + E+A Y +A + P + + LGI+C L EA + EA
Sbjct: 488 WNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEA 545
>gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sapiens]
Length = 654
Score = 35.4 bits (80), Expect = 0.31
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 945 FAKAEEYLQQAAQMD--YLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFI 1002
F + +E A ++D ++P+V G L+ LSG + +A C+ +S + +
Sbjct: 483 FLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSV---RPNDYLL 539
Query: 1003 FLRLGLIYLEEKEYEKAKKTYMQACKRSPSCL-TWLGLGIACYRLEELTEAEDALSEA 1059
+ +LG + E+A Y +A + P + + LGI+C L EA + EA
Sbjct: 540 WNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEA 597
>gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapiens]
Length = 631
Score = 35.4 bits (80), Expect = 0.31
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 945 FAKAEEYLQQAAQMD--YLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFI 1002
F + +E A ++D ++P+V G L+ LSG + +A C+ +S + +
Sbjct: 460 FLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSV---RPNDYLL 516
Query: 1003 FLRLGLIYLEEKEYEKAKKTYMQACKRSPSCL-TWLGLGIACYRLEELTEAEDALSEA 1059
+ +LG + E+A Y +A + P + + LGI+C L EA + EA
Sbjct: 517 WNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEA 574
>gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens]
Length = 858
Score = 35.4 bits (80), Expect = 0.31
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 9/109 (8%)
Query: 933 LVLAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISF 992
L + Q H+ + F +Q+AA + + +V ++G L + GN EAK Y+ ++
Sbjct: 720 LFMEQQHLKEAGFC-----IQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTV 774
Query: 993 VVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPSC-LTWLGLG 1040
D I LGL+ A+K A +R +C W GLG
Sbjct: 775 NPDGVR---IMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLG 820
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,936,405
Number of Sequences: 37866
Number of extensions: 2098180
Number of successful extensions: 6478
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 6222
Number of HSP's gapped (non-prelim): 311
length of query: 1121
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1008
effective length of database: 13,968,660
effective search space: 14080409280
effective search space used: 14080409280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.