Search of human proteins with 228480221

Search of human proteins with 228480221

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|228480221 four and a half LIM domains 1 isoform 4 [Homo
sapiens]
         (194 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]   444   e-125
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]   387   e-108
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]   387   e-108
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]   387   e-108
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]   387   e-108
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]   387   e-108
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]    387   e-108
gi|87159836 four and a half LIM domains 2 [Homo sapiens]              193   7e-50
gi|87159834 four and a half LIM domains 2 [Homo sapiens]              193   7e-50
gi|42403575 four and a half LIM domains 2 [Homo sapiens]              193   7e-50
gi|87159832 four and a half LIM domains 2 [Homo sapiens]              193   7e-50
gi|54112385 four and a half LIM domains 3 [Homo sapiens]              182   1e-46
gi|30410801 activator of cAMP-responsive element modulator (CREM...   180   8e-46
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]             99   2e-21
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              99   2e-21
gi|170932518 paxillin isoform 3 [Homo sapiens]                         92   3e-19
gi|170932516 paxillin isoform 2 [Homo sapiens]                         92   3e-19
gi|170932514 paxillin isoform 1 [Homo sapiens]                         92   3e-19
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]             87   7e-18
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]             87   7e-18
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]              87   9e-18
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]              87   9e-18
gi|221316659 leupaxin isoform 1 [Homo sapiens]                         83   2e-16
gi|4758670 leupaxin isoform 2 [Homo sapiens]                           83   2e-16
gi|109638745 transforming growth factor beta 1 induced transcrip...    82   3e-16
gi|21361591 transforming growth factor beta 1 induced transcript...    82   3e-16
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]     75   3e-14
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]     75   3e-14
gi|38524620 prickle-like 2 [Homo sapiens]                              74   8e-14
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...    74   1e-13

>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
          Length = 194

 Score =  444 bits (1142), Expect = e-125
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180

Query: 181 NPGTTTASTAKNAP 194
           NPGTTTASTAKNAP
Sbjct: 181 NPGTTTASTAKNAP 194


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  387 bits (994), Expect = e-108
 Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK +    + +  +D
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 178

Query: 181 NP 182
            P
Sbjct: 179 QP 180



 Score =  109 bits (272), Expect = 2e-24
 Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           DCF C  C + +    F    + +YCV C++   AK C  C
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224



 Score = 87.0 bits (214), Expect = 9e-18
 Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 5/152 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+  +    +  K     C+ C +   A  CV+C K I   S  + Y+++ WH  
Sbjct: 127 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHAD 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA---GDQNVEYKGTV 121
           CF C  C   LA + F A +++  C  C     + KC GC   I     G   V Y+G  
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           WH  CF C  C   +    F    E  YC  C
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276



 Score = 73.9 bits (180), Expect = 8e-14
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279


>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
          Length = 323

 Score =  387 bits (994), Expect = e-108
 Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK +    + +  +D
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 178

Query: 181 NP 182
            P
Sbjct: 179 QP 180



 Score =  109 bits (272), Expect = 2e-24
 Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           DCF C  C + +    F    + +YCV C++   AK C  C
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 14/46 (30%), Positives = 23/46 (50%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI 47
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPI 228


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  387 bits (994), Expect = e-108
 Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK +    + +  +D
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 178

Query: 181 NP 182
            P
Sbjct: 179 QP 180



 Score =  109 bits (272), Expect = 2e-24
 Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           DCF C  C + +    F    + +YCV C++   AK C  C
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224



 Score = 87.0 bits (214), Expect = 9e-18
 Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 5/152 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+  +    +  K     C+ C +   A  CV+C K I   S  + Y+++ WH  
Sbjct: 127 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHAD 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA---GDQNVEYKGTV 121
           CF C  C   LA + F A +++  C  C     + KC GC   I     G   V Y+G  
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           WH  CF C  C   +    F    E  YC  C
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276



 Score = 73.9 bits (180), Expect = 8e-14
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score =  387 bits (994), Expect = e-108
 Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 30  MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 89

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 90  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK +    + +  +D
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 207

Query: 181 NP 182
            P
Sbjct: 208 QP 209



 Score =  109 bits (272), Expect = 2e-24
 Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 95  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 154

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 155 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 212

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           DCF C  C + +    F    + +YCV C++   AK C  C
Sbjct: 213 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 253



 Score = 87.0 bits (214), Expect = 9e-18
 Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 5/152 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+  +    +  K     C+ C +   A  CV+C K I   S  + Y+++ WH  
Sbjct: 156 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHAD 213

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA---GDQNVEYKGTV 121
           CF C  C   LA + F A +++  C  C     + KC GC   I     G   V Y+G  
Sbjct: 214 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 273

Query: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           WH  CF C  C   +    F    E  YC  C
Sbjct: 274 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 305



 Score = 73.9 bits (180), Expect = 8e-14
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 212 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 271

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 272 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 308


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score =  387 bits (994), Expect = e-108
 Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 17  MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 77  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK +    + +  +D
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 194

Query: 181 NP 182
            P
Sbjct: 195 QP 196



 Score =  109 bits (272), Expect = 2e-24
 Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 82  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 141

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 142 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 199

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           DCF C  C + +    F    + +YCV C++   AK C  C
Sbjct: 200 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 240



 Score = 87.0 bits (214), Expect = 9e-18
 Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 5/152 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+  +    +  K     C+ C +   A  CV+C K I   S  + Y+++ WH  
Sbjct: 143 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHAD 200

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA---GDQNVEYKGTV 121
           CF C  C   LA + F A +++  C  C     + KC GC   I     G   V Y+G  
Sbjct: 201 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 260

Query: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           WH  CF C  C   +    F    E  YC  C
Sbjct: 261 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 292



 Score = 73.9 bits (180), Expect = 8e-14
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 258

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 259 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  387 bits (994), Expect = e-108
 Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK +    + +  +D
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 178

Query: 181 NP 182
            P
Sbjct: 179 QP 180



 Score =  109 bits (272), Expect = 2e-24
 Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           DCF C  C + +    F    + +YCV C++   AK C  C
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224



 Score = 87.0 bits (214), Expect = 9e-18
 Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 5/152 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+  +    +  K     C+ C +   A  CV+C K I   S  + Y+++ WH  
Sbjct: 127 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHAD 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA---GDQNVEYKGTV 121
           CF C  C   LA + F A +++  C  C     + KC GC   I     G   V Y+G  
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           WH  CF C  C   +    F    E  YC  C
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276



 Score = 73.9 bits (180), Expect = 8e-14
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  193 bits (491), Expect = 7e-50
 Identities = 79/174 (45%), Positives = 113/174 (64%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPV 174
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K +    V
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGV 174



 Score =  125 bits (313), Expect = 3e-29
 Identities = 52/161 (32%), Positives = 84/161 (52%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGC 224



 Score =  110 bits (274), Expect = 1e-24
 Identities = 49/151 (32%), Positives = 74/151 (49%), Gaps = 4/151 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F CH C+ P+  K ++ KD  + C+ C++K  A  CV+C+KPI      V Y+ + WH  
Sbjct: 127 FICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTYREQPWHKE 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI--VAGDQNVEYKGTVW 122
           CF C  C   L+ + F A+D+   C  C     + KC GC   I  + G + + ++   W
Sbjct: 185 CFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQW 244

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H DCF C  C   +    F  + +D  C  C
Sbjct: 245 HNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60
           E F C  CR  L G+++  +D    CL CF    A  C  C  PI     +K + ++ R 
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
           WH+ CF C KC   L    F+ + + ILC  C
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  193 bits (491), Expect = 7e-50
 Identities = 79/174 (45%), Positives = 113/174 (64%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPV 174
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K +    V
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGV 174



 Score =  125 bits (313), Expect = 3e-29
 Identities = 52/161 (32%), Positives = 84/161 (52%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGC 224



 Score =  110 bits (274), Expect = 1e-24
 Identities = 49/151 (32%), Positives = 74/151 (49%), Gaps = 4/151 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F CH C+ P+  K ++ KD  + C+ C++K  A  CV+C+KPI      V Y+ + WH  
Sbjct: 127 FICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTYREQPWHKE 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI--VAGDQNVEYKGTVW 122
           CF C  C   L+ + F A+D+   C  C     + KC GC   I  + G + + ++   W
Sbjct: 185 CFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQW 244

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H DCF C  C   +    F  + +D  C  C
Sbjct: 245 HNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60
           E F C  CR  L G+++  +D    CL CF    A  C  C  PI     +K + ++ R 
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
           WH+ CF C KC   L    F+ + + ILC  C
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  193 bits (491), Expect = 7e-50
 Identities = 79/174 (45%), Positives = 113/174 (64%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPV 174
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K +    V
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGV 174



 Score =  125 bits (313), Expect = 3e-29
 Identities = 52/161 (32%), Positives = 84/161 (52%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGC 224



 Score =  110 bits (274), Expect = 1e-24
 Identities = 49/151 (32%), Positives = 74/151 (49%), Gaps = 4/151 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F CH C+ P+  K ++ KD  + C+ C++K  A  CV+C+KPI      V Y+ + WH  
Sbjct: 127 FICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTYREQPWHKE 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI--VAGDQNVEYKGTVW 122
           CF C  C   L+ + F A+D+   C  C     + KC GC   I  + G + + ++   W
Sbjct: 185 CFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQW 244

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H DCF C  C   +    F  + +D  C  C
Sbjct: 245 HNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60
           E F C  CR  L G+++  +D    CL CF    A  C  C  PI     +K + ++ R 
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
           WH+ CF C KC   L    F+ + + ILC  C
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275


>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  193 bits (491), Expect = 7e-50
 Identities = 79/174 (45%), Positives = 113/174 (64%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPV 174
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K +    V
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGV 174



 Score =  125 bits (313), Expect = 3e-29
 Identities = 52/161 (32%), Positives = 84/161 (52%), Gaps = 2/161 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGC 224



 Score =  110 bits (274), Expect = 1e-24
 Identities = 49/151 (32%), Positives = 74/151 (49%), Gaps = 4/151 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F CH C+ P+  K ++ KD  + C+ C++K  A  CV+C+KPI      V Y+ + WH  
Sbjct: 127 FICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTYREQPWHKE 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI--VAGDQNVEYKGTVW 122
           CF C  C   L+ + F A+D+   C  C     + KC GC   I  + G + + ++   W
Sbjct: 185 CFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQW 244

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H DCF C  C   +    F  + +D  C  C
Sbjct: 245 HNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60
           E F C  CR  L G+++  +D    CL CF    A  C  C  PI     +K + ++ R 
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
           WH+ CF C KC   L    F+ + + ILC  C
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score =  182 bits (463), Expect = 1e-46
 Identities = 77/182 (42%), Positives = 113/182 (62%), Gaps = 2/182 (1%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M+E FDC  C + L G+KY+Q D    C+ C+D   ANTC EC++ IG DS+E+ Y++R 
Sbjct: 1   MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           +H+ CFRC +C   LA+E F  +D+++LCN C     S +C  C + ++ G + +EY G 
Sbjct: 61  FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
            WH+ CF CS C+Q +G+ SF P     YCV C+E KFA  C +C+K L +  V +  +D
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTY--RD 178

Query: 181 NP 182
            P
Sbjct: 179 QP 180



 Score =  106 bits (265), Expect = 1e-23
 Identities = 47/166 (28%), Positives = 77/166 (46%), Gaps = 2/166 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+  L  + +  +D    C  C+    ++ C  C + +   S+++ Y  + WH+ 
Sbjct: 66  FRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEH 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C  PL + +FV       C  C   + +P+C  C K +  G   V Y+   WH+
Sbjct: 126 CFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQG--GVTYRDQPWHR 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLV 170
           +C  C+ C+  +    F  + ED YCV C    FA  C  C + +V
Sbjct: 184 ECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIV 229



 Score =  100 bits (248), Expect = 1e-21
 Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V   G H C+ C++   A  C  C K +      V Y+++ WH  
Sbjct: 127 FLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG--VTYRDQPWHRE 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA--GDQNVEYKGTVW 122
           C  C  C  PLA + F ++D    C  C     +PKC  C + IV   G + V ++   W
Sbjct: 185 CLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHW 244

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
           H +CF+C+ C   +    F P G+   C  C +
Sbjct: 245 HHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277


>gi|30410801 activator of cAMP-responsive element modulator (CREM)
           in testis [Homo sapiens]
          Length = 284

 Score =  180 bits (456), Expect = 8e-46
 Identities = 76/163 (46%), Positives = 101/163 (61%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
            CF C NC+Q IGT     K    YCV C E +FA +C  C K
Sbjct: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKK 168



 Score =  120 bits (301), Expect = 7e-28
 Identities = 48/163 (29%), Positives = 84/163 (51%), Gaps = 2/163 (1%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C   L  K +  KD    C +C+   C++ C  C++ I   S+++ +K  +WH+T
Sbjct: 67  FKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHET 126

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C  C  P+  +  ++K++   C  C  +E +  C  C K I +G   + +   +WHK
Sbjct: 127 CFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSG--GITFCDQLWHK 184

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
           +CF CS C++ +    F  + +  +C+ C+   +A  CV C+K
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSK 227



 Score = 95.9 bits (237), Expect = 2e-20
 Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 4/151 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR P+  K  + K+  + C+ CF+K  A+ C  C+K I   S  + + ++ WH  
Sbjct: 128 FVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI--TSGGITFCDQLWHKE 185

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI--VAGDQNVEYKGTVW 122
           CF C+ C   L  E F+++D+   C  C     + KC  C K I  + G + + ++ + W
Sbjct: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQW 245

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H +CF C  C   +    F  + ++ +C  C
Sbjct: 246 HSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276



 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282



 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 34/127 (26%), Positives = 52/127 (40%)

Query: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125
           F C  C   L  + +V KD+   C  C  R  S  C+ C K I +  +++ YK   WH+ 
Sbjct: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65

Query: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKDNPGTT 185
           CF C+ C   +    F  K E   C  C+  + +  C  C + ++        K N    
Sbjct: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125

Query: 186 TASTAKN 192
           T    +N
Sbjct: 126 TCFVCEN 132


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E+F C YC+  L    +V++  +  C +C+++F A  C +C   I  +   +H   + WH
Sbjct: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
            TCF CA C  P  N  F  +D +  C K      S KC GC   + AGD+ +E  G  W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
           H  CF C+ C   +    F+ K +   C
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608



 Score = 64.3 bits (155), Expect = 6e-11
 Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 2/108 (1%)

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 118
           R WH   F CA C   LA+  FV + N + C +C  +  +P C  C   I+   + +   
Sbjct: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 515

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCN 166
              WH  CF C+ CK+  G   F  +  + YC   +   F+  C  C+
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCD 563



 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 28/87 (32%), Positives = 39/87 (44%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+ P     +  +DG   C K +    +  C  C  P+ A  K +      WHDT
Sbjct: 524 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 583

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNK 91
           CF CA C   L  + F +K ++ LC K
Sbjct: 584 CFICAVCHVNLEGQPFYSKKDRPLCKK 610



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 19/48 (39%), Positives = 25/48 (52%)

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCN 166
           G  WH + FTC+ CK  +    F  +  + YC  C+E  FA  C KCN
Sbjct: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCN 504


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E+F C YC+  L    +V++  +  C +C+++F A  C +C   I  +   +H   + WH
Sbjct: 573 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 630

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
            TCF CA C  P  N  F  +D +  C K      S KC GC   + AGD+ +E  G  W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
           H  CF C+ C   +    F+ K +   C
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC 718



 Score = 64.3 bits (155), Expect = 6e-11
 Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 2/108 (1%)

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 118
           R WH   F CA C   LA+  FV + N + C +C  +  +P C  C   I+   + +   
Sbjct: 568 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 625

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCN 166
              WH  CF C+ CK+  G   F  +  + YC   +   F+  C  C+
Sbjct: 626 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCD 673



 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 28/87 (32%), Positives = 39/87 (44%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+ P     +  +DG   C K +    +  C  C  P+ A  K +      WHDT
Sbjct: 634 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 693

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNK 91
           CF CA C   L  + F +K ++ LC K
Sbjct: 694 CFICAVCHVNLEGQPFYSKKDRPLCKK 720



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 19/48 (39%), Positives = 25/48 (52%)

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCN 166
           G  WH + FTC+ CK  +    F  +  + YC  C+E  FA  C KCN
Sbjct: 567 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCN 614


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 51/165 (30%), Positives = 72/165 (43%), Gaps = 4/165 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +  + + ++DG   C K +    +  C  C  PI    K V   +R WH
Sbjct: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 270

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F CA+C      E F  KD K  C K      +PKC GC +AI+  +  +    T+W
Sbjct: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 328

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
           H +CF C  C      GSFF      YC   +  +    C  C K
Sbjct: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQK 373



 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 4/151 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C      + + +KDG   C K +    A  C  C + I  +   +   N  WH
Sbjct: 272 EHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLWH 329

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C +C  P  N +F   D +  C           C GC K I    + +      +
Sbjct: 330 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITG--RCITAMAKKF 387

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H + F C+ C + +  G+F  + +  YC  C
Sbjct: 388 HPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 418



 Score = 61.2 bits (147), Expect = 5e-10
 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 4/132 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    + V    + WH   F C  C   + +  F  +D +  C K      SP
Sbjct: 191 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ V      WH + F C+ C    G   F  K    YC   +   FA
Sbjct: 249 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306

Query: 160 KHCVKCNKGLVK 171
             C  C + +++
Sbjct: 307 PKCGGCARAILE 318


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 51/165 (30%), Positives = 72/165 (43%), Gaps = 4/165 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +  + + ++DG   C K +    +  C  C  PI    K V   +R WH
Sbjct: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 403

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F CA+C      E F  KD K  C K      +PKC GC +AI+  +  +    T+W
Sbjct: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 461

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
           H +CF C  C      GSFF      YC   +  +    C  C K
Sbjct: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQK 506



 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 4/151 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C      + + +KDG   C K +    A  C  C + I  +   +   N  WH
Sbjct: 405 EHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLWH 462

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C +C  P  N +F   D +  C           C GC K I    + +      +
Sbjct: 463 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITG--RCITAMAKKF 520

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H + F C+ C + +  G+F  + +  YC  C
Sbjct: 521 HPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 551



 Score = 61.2 bits (147), Expect = 5e-10
 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 4/132 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    + V    + WH   F C  C   + +  F  +D +  C K      SP
Sbjct: 324 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ V      WH + F C+ C    G   F  K    YC   +   FA
Sbjct: 382 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439

Query: 160 KHCVKCNKGLVK 171
             C  C + +++
Sbjct: 440 PKCGGCARAILE 451


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 51/165 (30%), Positives = 72/165 (43%), Gaps = 4/165 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +  + + ++DG   C K +    +  C  C  PI    K V   +R WH
Sbjct: 380 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 437

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F CA+C      E F  KD K  C K      +PKC GC +AI+  +  +    T+W
Sbjct: 438 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 495

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
           H +CF C  C      GSFF      YC   +  +    C  C K
Sbjct: 496 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQK 540



 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 4/151 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C      + + +KDG   C K +    A  C  C + I  +   +   N  WH
Sbjct: 439 EHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLWH 496

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C +C  P  N +F   D +  C           C GC K I    + +      +
Sbjct: 497 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITG--RCITAMAKKF 554

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H + F C+ C + +  G+F  + +  YC  C
Sbjct: 555 HPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 585



 Score = 61.2 bits (147), Expect = 5e-10
 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 4/132 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    + V    + WH   F C  C   + +  F  +D +  C K      SP
Sbjct: 358 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 415

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ V      WH + F C+ C    G   F  K    YC   +   FA
Sbjct: 416 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473

Query: 160 KHCVKCNKGLVK 171
             C  C + +++
Sbjct: 474 PKCGGCARAILE 485


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score = 87.4 bits (215), Expect = 7e-18
 Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 2/148 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E+F+C +C++ +    +V++ G   C  C++KF A  C  C++ I  +   +    + WH
Sbjct: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWH 390

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
            +CF C  C  P+ N  F  +D +  C           C GC   I AGD  +E  G  W
Sbjct: 391 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 450

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
           H  CF CS C + +   +FF K +   C
Sbjct: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLC 478



 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 28/87 (32%), Positives = 38/87 (43%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  P++   +  +DG   C   +       C  C  PI A    +      WHDT
Sbjct: 394 FVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDT 453

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNK 91
           CF C+ C   L  +TF +K +K LC K
Sbjct: 454 CFVCSVCCESLEGQTFFSKKDKPLCKK 480



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 2/105 (1%)

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH   F CA C + +A   FV +   + C  C  +  +P+C  C + I+ G+     K T
Sbjct: 330 WHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL-GEVISALKQT 388

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
            WH  CF C  C + I    F  +  + YC T +   F   C  C
Sbjct: 389 -WHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGC 432



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 7/97 (7%)

Query: 74  PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCK 133
           P   +T V +   I   K T     P C  C   ++ G   V   G  WH + F C++CK
Sbjct: 289 PSDQDTLVQRAEHIPAGKRT-----PMCAHC-NQVIRGPFLVAL-GKSWHPEEFNCAHCK 341

Query: 134 QVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLV 170
             +    F  +    YC  C+E  FA  C +C + ++
Sbjct: 342 NTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL 378


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score = 87.4 bits (215), Expect = 7e-18
 Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 2/148 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E+F+C +C++ +    +V++ G   C  C++KF A  C  C++ I  +   +    + WH
Sbjct: 442 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWH 499

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
            +CF C  C  P+ N  F  +D +  C           C GC   I AGD  +E  G  W
Sbjct: 500 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 559

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
           H  CF CS C + +   +FF K +   C
Sbjct: 560 HDTCFVCSVCCESLEGQTFFSKKDKPLC 587



 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 28/87 (32%), Positives = 38/87 (43%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  P++   +  +DG   C   +       C  C  PI A    +      WHDT
Sbjct: 503 FVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDT 562

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNK 91
           CF C+ C   L  +TF +K +K LC K
Sbjct: 563 CFVCSVCCESLEGQTFFSKKDKPLCKK 589



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 2/105 (1%)

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH   F CA C + +A   FV +   + C  C  +  +P+C  C + I+ G+     K T
Sbjct: 439 WHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL-GEVISALKQT 497

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
            WH  CF C  C + I    F  +  + YC T +   F   C  C
Sbjct: 498 -WHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGC 541



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 7/97 (7%)

Query: 74  PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCK 133
           P   +T V +   I   K T     P C  C   ++ G   V   G  WH + F C++CK
Sbjct: 398 PSDQDTLVQRAEHIPAGKRT-----PMCAHC-NQVIRGPFLVAL-GKSWHPEEFNCAHCK 450

Query: 134 QVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLV 170
             +    F  +    YC  C+E  FA  C +C + ++
Sbjct: 451 NTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL 487


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score = 87.0 bits (214), Expect = 9e-18
 Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E+F C  C   L+   + ++ G   C  C+D   A +C +C+K I  +   +H     WH
Sbjct: 270 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 327

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF CA C  P+ N  F  ++    C +   +    KC GC   I AGD+ +E  G  W
Sbjct: 328 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 387

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
           H  CF C+ C+  +   +F+ K +   C
Sbjct: 388 HDTCFVCAICQINLEGKTFYSKKDRPLC 415



 Score = 53.9 bits (128), Expect = 8e-08
 Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 4/127 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C +C K I    + +      +H   F C++C   L    F  +   I C  C     +P
Sbjct: 248 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
            C  C K I  G+     K T WH  CFTC+ CK  I   +F+ +    YC   +E  F 
Sbjct: 306 SCAKCKKKIT-GEIMHALKMT-WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 363

Query: 160 KHCVKCN 166
             C  C+
Sbjct: 364 TKCHGCD 370



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 98  SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
           +P C  C K ++ G   V   G  +H + F CS C +V+  G FF +    +C  C++ +
Sbjct: 245 TPVCHQCHK-VIRGRYLVAL-GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVR 302

Query: 158 FAKHCVKCNK 167
           +A  C KC K
Sbjct: 303 YAPSCAKCKK 312


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score = 87.0 bits (214), Expect = 9e-18
 Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E+F C  C   L+   + ++ G   C  C+D   A +C +C+K I  +   +H     WH
Sbjct: 304 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 361

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF CA C  P+ N  F  ++    C +   +    KC GC   I AGD+ +E  G  W
Sbjct: 362 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 421

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
           H  CF C+ C+  +   +F+ K +   C
Sbjct: 422 HDTCFVCAICQINLEGKTFYSKKDRPLC 449



 Score = 53.9 bits (128), Expect = 8e-08
 Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 4/127 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C +C K I    + +      +H   F C++C   L    F  +   I C  C     +P
Sbjct: 282 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
            C  C K I  G+     K T WH  CFTC+ CK  I   +F+ +    YC   +E  F 
Sbjct: 340 SCAKCKKKIT-GEIMHALKMT-WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397

Query: 160 KHCVKCN 166
             C  C+
Sbjct: 398 TKCHGCD 404



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 98  SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
           +P C  C K ++ G   V   G  +H + F CS C +V+  G FF +    +C  C++ +
Sbjct: 279 TPVCHQCHK-VIRGRYLVAL-GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVR 336

Query: 158 FAKHCVKCNK 167
           +A  C KC K
Sbjct: 337 YAPSCAKCKK 346


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 46/165 (27%), Positives = 70/165 (42%), Gaps = 4/165 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 236

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
           H +CF C +C     TGSFF      +C   +  +    C  C +
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQ 339



 Score = 67.4 bits (163), Expect = 7e-12
 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 4/132 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272

Query: 160 KHCVKCNKGLVK 171
             C  CN+ +++
Sbjct: 273 PKCGGCNRPVLE 284



 Score = 60.8 bits (146), Expect = 7e-10
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 46/165 (27%), Positives = 70/165 (42%), Gaps = 4/165 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 174 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 231

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 232 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 289

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
           H +CF C +C     TGSFF      +C   +  +    C  C +
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQ 334



 Score = 67.4 bits (163), Expect = 7e-12
 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 4/132 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 152 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 210 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267

Query: 160 KHCVKCNKGLVK 171
             C  CN+ +++
Sbjct: 268 PKCGGCNRPVLE 279



 Score = 60.8 bits (146), Expect = 7e-10
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 233 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 290

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 291 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 348

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 349 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score = 82.0 bits (201), Expect = 3e-16
 Identities = 46/163 (28%), Positives = 66/163 (40%), Gaps = 4/163 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C   L G  + +KDG   C +C+ +  +  C  C +PI    K V      WH
Sbjct: 250 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTALGTHWH 307

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F C  C  P  +E F  ++ +  C +   +  +P+C+GC   I+  D  +     +W
Sbjct: 308 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 365

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           H DCF C  C      GSFF       C      +    C  C
Sbjct: 366 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATC 408



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 4/151 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C +P   + + +++G   C + F +  A  C  C+ PI      +   +  WH
Sbjct: 309 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALWH 366

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C +C  P +  +F   + + LC           C  C   +    + V   G  +
Sbjct: 367 PDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTG--RCVSALGRRF 424

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H D FTC+ C + +  GSF  +    YC  C
Sbjct: 425 HPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455



 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 39/126 (30%), Positives = 49/126 (38%), Gaps = 4/126 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C KPI    + V    R WH   F C  C   L   +F  KD    C +C     SP
Sbjct: 228 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C + I    + V   GT WH + F C +C +  G   F  +    YC       FA
Sbjct: 286 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343

Query: 160 KHCVKC 165
             C  C
Sbjct: 344 PRCQGC 349



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 2/67 (2%)

Query: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160
           C  C K I    Q V   G  WH + F C  C   +G  SFF K    +C  C+  +F+ 
Sbjct: 228 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285

Query: 161 HCVKCNK 167
            C  CN+
Sbjct: 286 RCGFCNQ 292


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score = 82.0 bits (201), Expect = 3e-16
 Identities = 46/163 (28%), Positives = 66/163 (40%), Gaps = 4/163 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C   L G  + +KDG   C +C+ +  +  C  C +PI    K V      WH
Sbjct: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTALGTHWH 290

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F C  C  P  +E F  ++ +  C +   +  +P+C+GC   I+  D  +     +W
Sbjct: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 348

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
           H DCF C  C      GSFF       C      +    C  C
Sbjct: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATC 391



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 4/151 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C +P   + + +++G   C + F +  A  C  C+ PI      +   +  WH
Sbjct: 292 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALWH 349

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C +C  P +  +F   + + LC           C  C   +    + V   G  +
Sbjct: 350 PDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTG--RCVSALGRRF 407

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
           H D FTC+ C + +  GSF  +    YC  C
Sbjct: 408 HPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438



 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 39/126 (30%), Positives = 49/126 (38%), Gaps = 4/126 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C KPI    + V    R WH   F C  C   L   +F  KD    C +C     SP
Sbjct: 211 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C + I    + V   GT WH + F C +C +  G   F  +    YC       FA
Sbjct: 269 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326

Query: 160 KHCVKC 165
             C  C
Sbjct: 327 PRCQGC 332



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 2/67 (2%)

Query: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160
           C  C K I    Q V   G  WH + F C  C   +G  SFF K    +C  C+  +F+ 
Sbjct: 211 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268

Query: 161 HCVKCNK 167
            C  CN+
Sbjct: 269 RCGFCNQ 275


>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
          Length = 276

 Score = 75.1 bits (183), Expect = 3e-14
 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 61
           A+ F C  CR  L G+ + QKDG   C  C+       C +C + +      +    + +
Sbjct: 109 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 165

Query: 62  HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 116
           H +CF C  C   + +E+F +   N++ C     R+ +P C  C   I+  D      +E
Sbjct: 166 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 225

Query: 117 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 162
             G  +H++C+ C +C+ ++         +P     +C  CH  + A  C
Sbjct: 226 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 275



 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 4/137 (2%)

Query: 35  FCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTT 94
           F  + C  C K +      V    R +H  CF C  C   LA ++F  KD + LC  C  
Sbjct: 81  FNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-Y 139

Query: 95  REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTC 153
           ++   +C  C +  V  D  +   G  +H  CFTC  C + IG  SF      + YC+  
Sbjct: 140 QDTLERCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDD 197

Query: 154 HETKFAKHCVKCNKGLV 170
              KFA  C  C   ++
Sbjct: 198 FYRKFAPVCSICENPII 214


>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score = 75.1 bits (183), Expect = 3e-14
 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 61
           A+ F C  CR  L G+ + QKDG   C  C+       C +C + +      +    + +
Sbjct: 206 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 262

Query: 62  HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 116
           H +CF C  C   + +E+F +   N++ C     R+ +P C  C   I+  D      +E
Sbjct: 263 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 322

Query: 117 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 162
             G  +H++C+ C +C+ ++         +P     +C  CH  + A  C
Sbjct: 323 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 372



 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 40/132 (30%), Positives = 56/132 (42%), Gaps = 4/132 (3%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C K +      V    R +H  CF C  C   LA ++F  KD + LC  C  ++   
Sbjct: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-YQDTLE 241

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTCHETKF 158
           +C  C +  V  D  +   G  +H  CFTC  C + IG  SF      + YC+     KF
Sbjct: 242 RCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299

Query: 159 AKHCVKCNKGLV 170
           A  C  C   ++
Sbjct: 300 APVCSICENPII 311


>gi|38524620 prickle-like 2 [Homo sapiens]
          Length = 844

 Score = 73.9 bits (180), Expect = 8e-14
 Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 62
           F C  C   L G++Y+ K+G   C  CF+   A  C  C + IG D  ++ Y  + WH  
Sbjct: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
           +TCF CA C   L    F+ K  +I C++ C+  ED
Sbjct: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 1/105 (0%)

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH  CF C  C   L +  +  +D KI C +       P+C  C + I A D+  E +G 
Sbjct: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
            WH   F C  C+ V+G   +  K    YC  C E+ +A++C  C
Sbjct: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTC 258



 Score = 63.9 bits (154), Expect = 8e-11
 Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C + L    Y  +DG   C +   +     C  C + I AD      + R WH  
Sbjct: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
            F C +C   L  + ++ K+ +  C  C     +  C  C + I      + Y G  WH 
Sbjct: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278

Query: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
            + CF C++CK+ +    F PK    +C
Sbjct: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306



 Score = 36.6 bits (83), Expect = 0.014
 Identities = 19/71 (26%), Positives = 28/71 (39%), Gaps = 4/71 (5%)

Query: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
           C+ C   I  GD  V       G  WH  CF C+ C +++    +F +    YC   H  
Sbjct: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189

Query: 157 KFAKHCVKCNK 167
                C  C++
Sbjct: 190 CLKPRCAACDE 200



 Score = 31.2 bits (69), Expect = 0.58
 Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 58
           F C +C+  L G+ ++ K G          FC+  C     P G+DS +  ++N
Sbjct: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 12/169 (7%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C        + + +G   C   F    A  C +C + I    + +   N  WH  
Sbjct: 36  FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
           CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  +Q + +K
Sbjct: 94  CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
              +H D F C+NC + +   +   KGE  YC+ CH+      C  C +
Sbjct: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRR 198



 Score = 65.5 bits (158), Expect = 3e-11
 Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 12/171 (7%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 93  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150

Query: 58  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
           N  +H   F CA C   L  +    K  ++ C  C  +   P C  C + I    + V  
Sbjct: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207

Query: 118 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
            G  WH + F C+ C K  +G   +  KG   YC T +   F   C  CN+
Sbjct: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGL-AYCETHYNQLFGDVCFHCNR 257



 Score = 61.2 bits (147), Expect = 5e-10
 Identities = 33/141 (23%), Positives = 56/141 (39%), Gaps = 7/141 (4%)

Query: 39  TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
           TC  C+       K V+     +H+ CF CA+C        F   + +  C        +
Sbjct: 9   TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68

Query: 99  PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
           P C  C + I+   + ++     WH +CF C  C++V+    F        C  CH  + 
Sbjct: 69  PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126

Query: 159 AKH-----CVKCNKGLVKAPV 174
           A+      C KC+  + + P+
Sbjct: 127 ARGLGKYICQKCHAIIDEQPL 147



 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 37/130 (28%), Positives = 49/130 (37%), Gaps = 5/130 (3%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           + F+C  C   L       K G   CL C DK     C  CR+PI  + + V+   + WH
Sbjct: 157 DHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPI--EGRVVNAMGKQWH 213

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F CAKC  P        +     C     +     C  C   ++ GD  V      W
Sbjct: 214 VEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHC-NRVIEGDV-VSALNKAW 271

Query: 123 HKDCFTCSNC 132
             +CF CS C
Sbjct: 272 CVNCFACSTC 281



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 3/91 (3%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C  P  G ++ ++ G   C   +++   + C  C + I  D   V   N+ W 
Sbjct: 215 EHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGD--VVSALNKAWC 272

Query: 63  DTCFRCAKCLHPLA-NETFVAKDNKILCNKC 92
             CF C+ C   L     FV  D K +C KC
Sbjct: 273 VNCFACSTCNTKLTLKNKFVEFDMKPVCKKC 303



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 19/73 (26%), Positives = 32/73 (43%)

Query: 98  SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
           S  C+ C       ++ V   G ++H+ CF C+ C Q    G F+      YC    +  
Sbjct: 7   SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66

Query: 158 FAKHCVKCNKGLV 170
           FA  C +C + ++
Sbjct: 67  FAPCCHQCGEFII 79


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.494 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,885,389
Number of Sequences: 37866
Number of extensions: 444015
Number of successful extensions: 4580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 463
Number of HSP's that attempted gapping in prelim test: 1977
Number of HSP's gapped (non-prelim): 2065
length of query: 194
length of database: 18,247,518
effective HSP length: 97
effective length of query: 97
effective length of database: 14,574,516
effective search space: 1413728052
effective search space used: 1413728052
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.