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Search of human proteins with 228480205
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|228480205 four and a half LIM domains 1 isoform 5 [Homo
sapiens]
(296 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 669 0.0
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 655 0.0
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 636 0.0
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 636 0.0
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 636 0.0
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 525 e-149
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens] 387 e-108
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 335 2e-92
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 335 2e-92
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 335 2e-92
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 335 2e-92
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 297 7e-81
gi|30410801 activator of cAMP-responsive element modulator (CREM... 290 8e-79
gi|170932518 paxillin isoform 3 [Homo sapiens] 120 1e-27
gi|170932516 paxillin isoform 2 [Homo sapiens] 120 1e-27
gi|170932514 paxillin isoform 1 [Homo sapiens] 120 1e-27
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 120 2e-27
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 119 4e-27
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 119 4e-27
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 119 4e-27
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 119 4e-27
gi|221316659 leupaxin isoform 1 [Homo sapiens] 117 9e-27
gi|4758670 leupaxin isoform 2 [Homo sapiens] 117 9e-27
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 112 5e-25
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 112 5e-25
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 109 3e-24
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 109 3e-24
gi|109638745 transforming growth factor beta 1 induced transcrip... 105 5e-23
gi|21361591 transforming growth factor beta 1 induced transcript... 105 5e-23
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 104 8e-23
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 669 bits (1727), Expect = 0.0
Identities = 296/296 (100%), Positives = 296/296 (100%)
Query: 1 MASHRHSGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECR 60
MASHRHSGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECR
Sbjct: 1 MASHRHSGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECR 60
Query: 61 KPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGC 120
KPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGC
Sbjct: 61 KPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGC 120
Query: 121 FKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVK 180
FKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVK
Sbjct: 121 FKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVK 180
Query: 181 CNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 240
CNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC
Sbjct: 181 CNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 240
Query: 241 KNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
KNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL
Sbjct: 241 KNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 655 bits (1690), Expect = 0.0
Identities = 289/290 (99%), Positives = 290/290 (100%)
Query: 7 SGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGAD 66
+GPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGAD
Sbjct: 20 AGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGAD 79
Query: 67 SKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA 126
SKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA
Sbjct: 80 SKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA 139
Query: 127 GDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAIT 186
GDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAIT
Sbjct: 140 GDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAIT 199
Query: 187 SGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 246
SGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 200 SGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 259
Query: 247 FGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
FGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL
Sbjct: 260 FGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 309
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 636 bits (1641), Expect = 0.0
Identities = 280/280 (100%), Positives = 280/280 (100%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 636 bits (1641), Expect = 0.0
Identities = 280/280 (100%), Positives = 280/280 (100%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 636 bits (1641), Expect = 0.0
Identities = 280/280 (100%), Positives = 280/280 (100%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 525 bits (1351), Expect = e-149
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 246
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
Score = 150 bits (380), Expect = 1e-36
Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Query: 82 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 141
F C C PL + +V KD C KC + + C C K I A + V YK WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 142 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 199
CF C+ C + +F K C C + + C C KAI +G + Y+ WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
Query: 200 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 259
DCF C C + + F + +YCV C++ AK C C IT G + Y+ Q
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
Query: 260 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 294
WH CF C CS LA +RF ++Q YC DC K
Sbjct: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
Score = 73.9 bits (180), Expect = 2e-13
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 258
A+ F C C L G+++ + + C+ C+ F A C C+ PI G S V Y+
Sbjct: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
Query: 259 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
+ WHD CF C KC LAN+ FV ++ C C +
Sbjct: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
Length = 194
Score = 387 bits (994), Expect = e-108
Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 194
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK + + + +D
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
Query: 195 QP 196
P
Sbjct: 181 NP 182
Score = 109 bits (272), Expect = 3e-24
Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)
Query: 82 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 141
F C C PL + +V KD C KC + + C C K I A + V YK WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 142 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 199
CF C+ C + +F K C C + + C C KAI +G + Y+ WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
Query: 200 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 240
DCF C C + + F + +YCV C++ AK C C
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
Score = 87.0 bits (214), Expect = 2e-17
Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 5/152 (3%)
Query: 143 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHAD 200
F C C+ + + K C+ C + A CV+C K I S + Y+++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 201 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 260
CF C C LA + F A +++ C C + KC GC I G V Y+G
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA---GDQNVEYKGTV 121
Query: 261 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 292
WH CF C C + F E YC C
Sbjct: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153
Score = 73.9 bits (180), Expect = 2e-13
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 258
A+ F C C L G+++ + + C+ C+ F A C C+ PI G S V Y+
Sbjct: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
Query: 259 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
+ WHD CF C KC LAN+ FV ++ C C +
Sbjct: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
Query: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
Query: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
Query: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 335 bits (860), Expect = 2e-92
Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G G G+ +++
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
Query: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
E + WH+ CF+CKKCS++L + F+ ++ + CPDC K +
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 297 bits (761), Expect = 7e-81
Identities = 123/278 (44%), Positives = 175/278 (62%), Gaps = 1/278 (0%)
Query: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K +T GG+TY+DQP
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
Query: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
WH +C VC C LAGQ+FT+ ++ YCV C+ A KC+ CK PI G G G V++
Sbjct: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLG-GGKYVSF 239
Query: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 294
E + WH CF C +CS +L + FV +QV C C++
Sbjct: 240 EDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
Score = 129 bits (323), Expect = 4e-30
Identities = 63/217 (29%), Positives = 95/217 (43%), Gaps = 7/217 (3%)
Query: 82 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 141
F CAKC L ++ D+ C C + C C + I + + Y+ +H+
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 142 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITYQDQPWHA 199
CF C C++ + F + + C C+ + F+ C C + + G + Y Q WH
Sbjct: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHE 124
Query: 200 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 259
CF+C C + L + F + +YCV CY+N A +CA C +T G V Y Q
Sbjct: 125 HCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG-----VTYRDQ 179
Query: 260 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
WH C C C LA ++F E YC C +L
Sbjct: 180 PWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGEL 216
>gi|30410801 activator of cAMP-responsive element modulator (CREM)
in testis [Homo sapiens]
Length = 284
Score = 290 bits (743), Expect = 8e-79
Identities = 121/272 (44%), Positives = 168/272 (61%), Gaps = 1/272 (0%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C YC L GKKYV KD C+ C+D+ +N C EC+KPI +DSK++ YK+R WH+
Sbjct: 6 FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 140
CF+C KC H L + F AKD ++LC +C + E S KC C + I+ G + +E+KG WH+
Sbjct: 66 CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
Query: 141 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 200
CF C NC+Q IGT K YCV C E +FA +C C K ITSGGIT+ DQ WH +
Sbjct: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
Query: 201 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 260
CF+C C K L ++F + +D +C+DCY + A KC C PI+G G+ + ++
Sbjct: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGL-TGAKFICFQDSQ 244
Query: 261 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 292
WH CF+C KCSV+L K F+ ++++C C
Sbjct: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
Score = 130 bits (326), Expect = 2e-30
Identities = 64/217 (29%), Positives = 96/217 (44%), Gaps = 7/217 (3%)
Query: 82 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 141
F C C L + +V KD+ C C R S C+ C K I + +++ YK WH+
Sbjct: 6 FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
Query: 142 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITYQDQPWHA 199
CF C+ C + F K E C C+ + + C C + I G + ++ WH
Sbjct: 66 CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
Query: 200 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 259
CFVC C + + + + E YCV C++ A C CK IT G + + Q
Sbjct: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGG-----ITFCDQ 180
Query: 260 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
WH CF C C +L ++F+ + +C DC L
Sbjct: 181 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHL 217
Score = 73.2 bits (178), Expect = 3e-13
Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 76
E F C CR L ++++ +D + C+ C++ AN CV C KPI +K + +++
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 114
WH CF C KC L + F+ ++ +I C KC + D+
Sbjct: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 120 bits (302), Expect = 1e-27
Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C +C++ + + + ++DG C K + + C C PI K V +R WH
Sbjct: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI--LDKVVTALDRTWH 270
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
F CA+C E F KD K C K +PKC GC +AI+ + + T+W
Sbjct: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 328
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 198
H +CF C C GSFF YC + + C C K IT IT + +H
Sbjct: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
+ FVC C K+L F D+ YC +C+
Sbjct: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 419
Score = 111 bits (277), Expect = 9e-25
Identities = 69/241 (28%), Positives = 95/241 (39%), Gaps = 9/241 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C C+KPI + V + WH F C C + + F +D + C K SP
Sbjct: 191 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
+C C I+ D+ V WH + F C+ C G F K YC + FA
Sbjct: 249 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
Query: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
C C +AI I+ + WH +CFVC C F + Q YC Y
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
Query: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
C+GC+ PITG + + +H F C C L F ++ YC +C K
Sbjct: 367 LCSGCQKPITG-----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLK 421
Query: 296 L 296
L
Sbjct: 422 L 422
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/113 (24%), Positives = 38/113 (33%), Gaps = 31/113 (27%)
Query: 203 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 236
VC C K +AGQ TA+ + Q YC Y N + +
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
C C PI VV ++WH F C +C + F + YC
Sbjct: 250 CYYCNGPIL-----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 297
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 120 bits (302), Expect = 1e-27
Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C +C++ + + + ++DG C K + + C C PI K V +R WH
Sbjct: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI--LDKVVTALDRTWH 403
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
F CA+C E F KD K C K +PKC GC +AI+ + + T+W
Sbjct: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 461
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 198
H +CF C C GSFF YC + + C C K IT IT + +H
Sbjct: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
+ FVC C K+L F D+ YC +C+
Sbjct: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 552
Score = 111 bits (277), Expect = 9e-25
Identities = 69/241 (28%), Positives = 95/241 (39%), Gaps = 9/241 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C C+KPI + V + WH F C C + + F +D + C K SP
Sbjct: 324 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
+C C I+ D+ V WH + F C+ C G F K YC + FA
Sbjct: 382 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
Query: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
C C +AI I+ + WH +CFVC C F + Q YC Y
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
Query: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
C+GC+ PITG + + +H F C C L F ++ YC +C K
Sbjct: 500 LCSGCQKPITG-----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLK 554
Query: 296 L 296
L
Sbjct: 555 L 555
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/113 (24%), Positives = 38/113 (33%), Gaps = 31/113 (27%)
Query: 203 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 236
VC C K +AGQ TA+ + Q YC Y N + +
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
C C PI VV ++WH F C +C + F + YC
Sbjct: 383 CYYCNGPIL-----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 430
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 120 bits (302), Expect = 1e-27
Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C +C++ + + + ++DG C K + + C C PI K V +R WH
Sbjct: 380 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI--LDKVVTALDRTWH 437
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
F CA+C E F KD K C K +PKC GC +AI+ + + T+W
Sbjct: 438 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 495
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 198
H +CF C C GSFF YC + + C C K IT IT + +H
Sbjct: 496 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 555
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
+ FVC C K+L F D+ YC +C+
Sbjct: 556 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 586
Score = 111 bits (277), Expect = 9e-25
Identities = 69/241 (28%), Positives = 95/241 (39%), Gaps = 9/241 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C C+KPI + V + WH F C C + + F +D + C K SP
Sbjct: 358 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 415
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
+C C I+ D+ V WH + F C+ C G F K YC + FA
Sbjct: 416 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473
Query: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
C C +AI I+ + WH +CFVC C F + Q YC Y
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533
Query: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
C+GC+ PITG + + +H F C C L F ++ YC +C K
Sbjct: 534 LCSGCQKPITG-----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLK 588
Query: 296 L 296
L
Sbjct: 589 L 589
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/113 (24%), Positives = 38/113 (33%), Gaps = 31/113 (27%)
Query: 203 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 236
VC C K +AGQ TA+ + Q YC Y N + +
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
C C PI VV ++WH F C +C + F + YC
Sbjct: 417 CYYCNGPIL-----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 464
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 120 bits (300), Expect = 2e-27
Identities = 79/282 (28%), Positives = 112/282 (39%), Gaps = 18/282 (6%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C C + + +G C F A C +C + I + + N WH
Sbjct: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 134
CFRC C LA+ FV + LC C RE K +G K I + +Q + +K
Sbjct: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
+H D F C+NC + + + KGE YC+ CH+ C C + I +
Sbjct: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNAMG 209
Query: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
+ WH + FVC C K G R + YC Y C C I G VV
Sbjct: 210 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG-----DVV 264
Query: 255 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 295
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 265 SALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
Score = 110 bits (275), Expect = 1e-24
Identities = 61/240 (25%), Positives = 95/240 (39%), Gaps = 13/240 (5%)
Query: 55 TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 114
TC C+ K V+ +H+ CF CA+C F + + C +
Sbjct: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
Query: 115 PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 174
P C C + I+ + ++ WH +CF C C++V+ F C CH +
Sbjct: 69 PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
Query: 175 AKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
A+ C KC+ I + +++ P+H D F C C K+L ++ + YC+ C+
Sbjct: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCH 185
Query: 230 KNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
C C+ PI G VV G+ WH F C KC R + YC
Sbjct: 186 DKMGVPICGACRRPIEG-----RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/221 (28%), Positives = 95/221 (42%), Gaps = 13/221 (5%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 73
E F C C++ L +V+ G H C C ++ A C +C I D + + +K
Sbjct: 93 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150
Query: 74 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 133
N +H F CA C L + K ++ C C + P C C + I + V
Sbjct: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207
Query: 134 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY 192
G WH + F C+ C K +G + KG YC T + F C CN+ I ++
Sbjct: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGL-AYCETHYNQLFGDVCFHCNRVIEGDVVSA 266
Query: 193 QDQPWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNF 232
++ W +CF C TC+ KL +F + + C CY+ F
Sbjct: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 13/189 (6%)
Query: 114 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 173
S C+ C ++ V G ++H+ CF C+ C Q G F+ YC +
Sbjct: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
Query: 174 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 233
FA C +C + I I + WH +CF C C + LA F ++ C C+
Sbjct: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
Query: 234 AKK-----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNL-ANKRFVFHQEQV 287
A+ C C I + ++ +H F+C C L A+ R + + ++
Sbjct: 127 ARGLGKYICQKCHAII-----DEQPLIFKNDPYHPDHFNCANCGKELTADAREL--KGEL 179
Query: 288 YCPDCAKKL 296
YC C K+
Sbjct: 180 YCLPCHDKM 188
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 119 bits (297), Expect = 4e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C C P + + +G C F A C C + I + + N WH
Sbjct: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 134
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 177
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 178 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 236
Query: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 291
Query: 255 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 295
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 292 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 49 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 108
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 30 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89
Query: 109 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 168
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 90 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
Query: 169 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 223
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 206
Query: 224 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 283
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 207 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 261
Query: 284 QEQVYC 289
+ YC
Sbjct: 262 KGLAYC 267
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 117 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 176
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
Query: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 236
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
Query: 237 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291
C C I + + ++H F+C C L + E +YC
Sbjct: 157 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 210
Query: 292 CAKKL 296
C K+
Sbjct: 211 CHDKM 215
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 119 bits (297), Expect = 4e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C C P + + +G C F A C C + I + + N WH
Sbjct: 36 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 93
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 134
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 94 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 150
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 151 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 209
Query: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 210 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 264
Query: 255 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 295
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 265 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 49 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 108
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 3 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 62
Query: 109 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 168
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 63 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 120
Query: 169 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 223
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 121 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 179
Query: 224 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 283
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 180 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 234
Query: 284 QEQVYC 289
+ YC
Sbjct: 235 KGLAYC 240
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 117 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 176
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 10 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 69
Query: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 236
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 70 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 129
Query: 237 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291
C C I + + ++H F+C C L + E +YC
Sbjct: 130 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 183
Query: 292 CAKKL 296
C K+
Sbjct: 184 CHDKM 188
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 119 bits (297), Expect = 4e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C C P + + +G C F A C C + I + + N WH
Sbjct: 41 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 98
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 134
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 99 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 155
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 156 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 214
Query: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 215 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 269
Query: 255 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 295
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 270 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 49 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 108
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 8 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 67
Query: 109 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 168
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 68 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 125
Query: 169 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 223
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 126 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 184
Query: 224 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 283
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 185 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 239
Query: 284 QEQVYC 289
+ YC
Sbjct: 240 KGLAYC 245
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 117 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 176
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 15 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 74
Query: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 236
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 75 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 134
Query: 237 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291
C C I + + ++H F+C C L + E +YC
Sbjct: 135 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 188
Query: 292 CAKKL 296
C K+
Sbjct: 189 CHDKM 193
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 119 bits (297), Expect = 4e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C C P + + +G C F A C C + I + + N WH
Sbjct: 65 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 122
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 134
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 123 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 179
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 180 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 238
Query: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 239 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 293
Query: 255 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 295
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 294 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 49 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 108
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 32 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 91
Query: 109 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 168
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 92 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 149
Query: 169 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 223
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 150 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 208
Query: 224 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 283
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 209 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 263
Query: 284 QEQVYC 289
+ YC
Sbjct: 264 KGLAYC 269
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 117 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 176
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 39 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 98
Query: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 236
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 99 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 158
Query: 237 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291
C C I + + ++H F+C C L + E +YC
Sbjct: 159 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 212
Query: 292 CAKKL 296
C K+
Sbjct: 213 CHDKM 217
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 117 bits (294), Expect = 9e-27
Identities = 66/241 (27%), Positives = 99/241 (41%), Gaps = 9/241 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C C+KPI K +H + WH F C C + + F + C + SP
Sbjct: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
+C C I+ D+ + WH + F CS+C +V G F K + YC F+
Sbjct: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
Query: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
C CN+ + ++ D WH +CFVC C + F ++ + +C Y +
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
Query: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
C GC PITG ++ G +H F C C L+ F ++ YC C K
Sbjct: 333 LCHGCGQPITG-----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
Query: 296 L 296
L
Sbjct: 388 L 388
Score = 107 bits (267), Expect = 1e-23
Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C +C++ + + ++ G C + + + C C PI K + N+ WH
Sbjct: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI--LDKVLTAMNQTWH 236
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
F C+ C E F KD K C K SPKC GC + ++ + + TVW
Sbjct: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 198
H +CF C +C TGSFF +C + + C C + IT I+ +H
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
+ FVC C +L+ F D+ YC C+
Sbjct: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
Score = 61.6 bits (148), Expect = 8e-10
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 5/113 (4%)
Query: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 236
HC C K I I Q WH + FVC C +++ F YC + Y + +
Sbjct: 156 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 215
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
CA C PI V+ Q+WH F C C + F ++ YC
Sbjct: 216 CAYCAAPIL-----DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC 263
Score = 60.8 bits (146), Expect = 1e-09
Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C +C + + + +KD C K F + C C +P+ + + WH
Sbjct: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
CF C C + +F D + C C GC + I + + G +
Sbjct: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 174
H + F C+ C + G F + + YC C F
Sbjct: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 117 bits (294), Expect = 9e-27
Identities = 66/241 (27%), Positives = 99/241 (41%), Gaps = 9/241 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C C+KPI K +H + WH F C C + + F + C + SP
Sbjct: 152 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
+C C I+ D+ + WH + F CS+C +V G F K + YC F+
Sbjct: 210 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267
Query: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
C CN+ + ++ D WH +CFVC C + F ++ + +C Y +
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327
Query: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
C GC PITG ++ G +H F C C L+ F ++ YC C K
Sbjct: 328 LCHGCGQPITG-----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 382
Query: 296 L 296
L
Sbjct: 383 L 383
Score = 107 bits (267), Expect = 1e-23
Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C +C++ + + ++ G C + + + C C PI K + N+ WH
Sbjct: 174 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI--LDKVLTAMNQTWH 231
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
F C+ C E F KD K C K SPKC GC + ++ + + TVW
Sbjct: 232 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 289
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 198
H +CF C +C TGSFF +C + + C C + IT I+ +H
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 349
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
+ FVC C +L+ F D+ YC C+
Sbjct: 350 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 380
Score = 61.6 bits (148), Expect = 8e-10
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 5/113 (4%)
Query: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 236
HC C K I I Q WH + FVC C +++ F YC + Y + +
Sbjct: 151 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 210
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
CA C PI V+ Q+WH F C C + F ++ YC
Sbjct: 211 CAYCAAPIL-----DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC 258
Score = 60.8 bits (146), Expect = 1e-09
Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C +C + + + +KD C K F + C C +P+ + + WH
Sbjct: 233 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 290
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
CF C C + +F D + C C GC + I + + G +
Sbjct: 291 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 348
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 174
H + F C+ C + G F + + YC C F
Sbjct: 349 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 112 bits (279), Expect = 5e-25
Identities = 53/155 (34%), Positives = 70/155 (45%), Gaps = 3/155 (1%)
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
G WH + FTC+ CK + F + + YC C+E FA C KCN I +
Sbjct: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
Query: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
Q WH CFVC C K F + + YC Y N + KC GC P+ G +
Sbjct: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEA---GDKFI 573
Query: 255 AYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
G +WHD CF C C VNL + F +++ C
Sbjct: 574 EALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 99.0 bits (245), Expect = 4e-21
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E+F C YC+ L +V++ + C +C+++F A C +C I + +H + WH
Sbjct: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
TCF CA C P N F +D + C K S KC GC + AGD+ +E G W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 166
H CF C+ C + F+ K + C
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 89.4 bits (220), Expect = 4e-18
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)
Query: 75 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 134
R WH F CA C LA+ FV + N + C +C + +P C C I+ + +
Sbjct: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 515
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 192
WH CF C+ CK+ G F + + YC + F+ C C+ + +G I
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
Query: 193 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 225
WH CF+C C L GQ F + +D+ C
Sbjct: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 70.5 bits (171), Expect = 2e-12
Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 5/112 (4%)
Query: 178 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 237
C CN I + + WH + F C C LA F ++ YC CY+ F A C
Sbjct: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
Query: 238 AGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
A C I G V+ Q+WH CF C C N F + YC
Sbjct: 501 AKCNTKIMG-----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYC 547
Score = 58.5 bits (140), Expect = 7e-09
Identities = 28/87 (32%), Positives = 39/87 (44%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C C+ P + +DG C K + + C C P+ A K + WHDT
Sbjct: 524 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 583
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNK 107
CF CA C L + F +K ++ LC K
Sbjct: 584 CFICAVCHVNLEGQPFYSKKDRPLCKK 610
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 292
C C N I +G +VA G+SWH F C C +LA+ FV Q VYC C
Sbjct: 441 CGHCNNVI----RGPFLVAM-GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERC 491
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 112 bits (279), Expect = 5e-25
Identities = 53/155 (34%), Positives = 70/155 (45%), Gaps = 3/155 (1%)
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
G WH + FTC+ CK + F + + YC C+E FA C KCN I +
Sbjct: 567 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 626
Query: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
Q WH CFVC C K F + + YC Y N + KC GC P+ G +
Sbjct: 627 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEA---GDKFI 683
Query: 255 AYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
G +WHD CF C C VNL + F +++ C
Sbjct: 684 EALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 99.0 bits (245), Expect = 4e-21
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E+F C YC+ L +V++ + C +C+++F A C +C I + +H + WH
Sbjct: 573 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 630
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
TCF CA C P N F +D + C K S KC GC + AGD+ +E G W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 166
H CF C+ C + F+ K + C
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 89.4 bits (220), Expect = 4e-18
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)
Query: 75 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 134
R WH F CA C LA+ FV + N + C +C + +P C C I+ + +
Sbjct: 568 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 625
Query: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 192
WH CF C+ CK+ G F + + YC + F+ C C+ + +G I
Sbjct: 626 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 685
Query: 193 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 225
WH CF+C C L GQ F + +D+ C
Sbjct: 686 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 70.5 bits (171), Expect = 2e-12
Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 5/112 (4%)
Query: 178 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 237
C CN I + + WH + F C C LA F ++ YC CY+ F A C
Sbjct: 551 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 610
Query: 238 AGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
A C I G V+ Q+WH CF C C N F + YC
Sbjct: 611 AKCNTKIMG-----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYC 657
Score = 58.5 bits (140), Expect = 7e-09
Identities = 28/87 (32%), Positives = 39/87 (44%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C C+ P + +DG C K + + C C P+ A K + WHDT
Sbjct: 634 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 693
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNK 107
CF CA C L + F +K ++ LC K
Sbjct: 694 CFICAVCHVNLEGQPFYSKKDRPLCKK 720
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 292
C C N I +G +VA G+SWH F C C +LA+ FV Q VYC C
Sbjct: 551 CGHCNNVI----RGPFLVAM-GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERC 601
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 109 bits (272), Expect = 3e-24
Identities = 56/176 (31%), Positives = 78/176 (44%), Gaps = 5/176 (2%)
Query: 114 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 173
+P C C K ++ G V G +H + F CS C +V+ G FF + +C C++ +
Sbjct: 245 TPVCHQCHK-VIRGRYLVAL-GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVR 302
Query: 174 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 233
+A C KC K IT + WH CF C C + + F E YC Y+
Sbjct: 303 YAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 362
Query: 234 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
KC GC I G + G SWHD CF C C +NL K F +++ C
Sbjct: 363 GTKCHGCDFKIDA---GDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 415
Score = 87.0 bits (214), Expect = 2e-17
Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E+F C C L+ + ++ G C C+D A +C +C+K I + +H WH
Sbjct: 270 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 327
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
CF CA C P+ N F ++ C + + KC GC I AGD+ +E G W
Sbjct: 328 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 387
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 166
H CF C+ C+ + +F+ K + C
Sbjct: 388 HDTCFVCAICQINLEGKTFYSKKDRPLC 415
Score = 76.3 bits (186), Expect = 3e-14
Identities = 51/172 (29%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C +C K I + + +H F C++C L F + I C C +P
Sbjct: 248 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
C C K I G+ K T WH CFTC+ CK I +F+ + YC +E F
Sbjct: 306 SCAKCKKKI-TGEIMHALKMT-WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 363
Query: 176 KHCVKCNKAITSGG--ITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 225
C C+ I +G + WH CFVC C L G+ F + +D+ C
Sbjct: 364 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 415
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 109 bits (272), Expect = 3e-24
Identities = 56/176 (31%), Positives = 78/176 (44%), Gaps = 5/176 (2%)
Query: 114 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 173
+P C C K ++ G V G +H + F CS C +V+ G FF + +C C++ +
Sbjct: 279 TPVCHQCHK-VIRGRYLVAL-GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVR 336
Query: 174 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 233
+A C KC K IT + WH CF C C + + F E YC Y+
Sbjct: 337 YAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
Query: 234 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
KC GC I G + G SWHD CF C C +NL K F +++ C
Sbjct: 397 GTKCHGCDFKIDA---GDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
Score = 87.0 bits (214), Expect = 2e-17
Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E+F C C L+ + ++ G C C+D A +C +C+K I + +H WH
Sbjct: 304 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 361
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
CF CA C P+ N F ++ C + + KC GC I AGD+ +E G W
Sbjct: 362 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 421
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 166
H CF C+ C+ + +F+ K + C
Sbjct: 422 HDTCFVCAICQINLEGKTFYSKKDRPLC 449
Score = 76.3 bits (186), Expect = 3e-14
Identities = 51/172 (29%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C +C K I + + +H F C++C L F + I C C +P
Sbjct: 282 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
C C K I G+ K T WH CFTC+ CK I +F+ + YC +E F
Sbjct: 340 SCAKCKKKI-TGEIMHALKMT-WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
Query: 176 KHCVKCNKAITSGG--ITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 225
C C+ I +G + WH CFVC C L G+ F + +D+ C
Sbjct: 398 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 105 bits (262), Expect = 5e-23
Identities = 72/241 (29%), Positives = 92/241 (38%), Gaps = 9/241 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C C KPI + V R WH F C C L +F KD C +C SP
Sbjct: 228 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
+C C + I + V GT WH + F C +C + G F + YC FA
Sbjct: 286 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343
Query: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
C C I I+ WH DCFVC C +G F E + C + +
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403
Query: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
CA C P+TG V+ G+ +H F C C L F + YC C K
Sbjct: 404 LCATCGLPVTG-----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLK 458
Query: 296 L 296
L
Sbjct: 459 L 459
Score = 101 bits (252), Expect = 7e-22
Identities = 57/211 (27%), Positives = 85/211 (40%), Gaps = 4/211 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C C L G + +KDG C +C+ + + C C +PI K V WH
Sbjct: 250 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPI--RHKMVTALGTHWH 307
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
F C C P +E F ++ + C + + +P+C+GC I+ D + +W
Sbjct: 308 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 365
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 198
H DCF C C GSFF C + C C +T ++ + +H
Sbjct: 366 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 425
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
D F C C + L F + YC C+
Sbjct: 426 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 456
Score = 36.6 bits (83), Expect = 0.027
Identities = 25/113 (22%), Positives = 40/113 (35%), Gaps = 31/113 (27%)
Query: 203 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 236
+C +C+K +AGQ TA+ + +C +CY + +
Sbjct: 227 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 286
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
C C PI +V G WH F C C ++ F + + YC
Sbjct: 287 CGFCNQPIR-----HKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC 334
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 105 bits (262), Expect = 5e-23
Identities = 72/241 (29%), Positives = 92/241 (38%), Gaps = 9/241 (3%)
Query: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115
C C KPI + V R WH F C C L +F KD C +C SP
Sbjct: 211 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268
Query: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
+C C + I + V GT WH + F C +C + G F + YC FA
Sbjct: 269 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
Query: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
C C I I+ WH DCFVC C +G F E + C + +
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
Query: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
CA C P+TG V+ G+ +H F C C L F + YC C K
Sbjct: 387 LCATCGLPVTG-----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLK 441
Query: 296 L 296
L
Sbjct: 442 L 442
Score = 101 bits (252), Expect = 7e-22
Identities = 57/211 (27%), Positives = 85/211 (40%), Gaps = 4/211 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E F C C L G + +KDG C +C+ + + C C +PI K V WH
Sbjct: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPI--RHKMVTALGTHWH 290
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
F C C P +E F ++ + C + + +P+C+GC I+ D + +W
Sbjct: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 348
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 198
H DCF C C GSFF C + C C +T ++ + +H
Sbjct: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408
Query: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
D F C C + L F + YC C+
Sbjct: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
Score = 36.6 bits (83), Expect = 0.027
Identities = 25/113 (22%), Positives = 40/113 (35%), Gaps = 31/113 (27%)
Query: 203 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 236
+C +C+K +AGQ TA+ + +C +CY + +
Sbjct: 210 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
C C PI +V G WH F C C ++ F + + YC
Sbjct: 270 CGFCNQPIR-----HKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC 317
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 104 bits (260), Expect = 8e-23
Identities = 60/200 (30%), Positives = 84/200 (42%), Gaps = 10/200 (5%)
Query: 90 PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCK 149
P +T V + I K T P C C ++ G V G WH + F C++CK
Sbjct: 289 PSDQDTLVQRAEHIPAGKRT-----PMCAHC-NQVIRGPFLVAL-GKSWHPEEFNCAHCK 341
Query: 150 QVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSK 209
+ F + YC C+E FA C +C + I I+ Q WH CFVCV C K
Sbjct: 342 NTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGK 401
Query: 210 KLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCK 269
+ F + + YC Y C GC+ PI G + G +WHD CF C
Sbjct: 402 PIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEA---GDMFLEALGYTWHDTCFVCS 458
Query: 270 KCSVNLANKRFVFHQEQVYC 289
C +L + F +++ C
Sbjct: 459 VCCESLEGQTFFSKKDKPLC 478
Score = 87.4 bits (215), Expect = 1e-17
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 2/148 (1%)
Query: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
E+F+C +C++ + +V++ G C C++KF A C C++ I + + + WH
Sbjct: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGE--VISALKQTWH 390
Query: 79 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138
+CF C C P+ N F +D + C C GC I AGD +E G W
Sbjct: 391 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 450
Query: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 166
H CF CS C + + +FF K + C
Sbjct: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLC 478
Score = 82.8 bits (203), Expect = 3e-16
Identities = 47/151 (31%), Positives = 68/151 (45%), Gaps = 4/151 (2%)
Query: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
WH F CA C + +A FV + + C C + +P+C C + I+ G+ K T
Sbjct: 330 WHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL-GEVISALKQT 388
Query: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQ--D 194
WH CF C C + I F + + YC T + F C C I +G + +
Sbjct: 389 -WHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALG 447
Query: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 225
WH CFVC C + L GQ F + +D+ C
Sbjct: 448 YTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
Score = 56.6 bits (135), Expect = 3e-08
Identities = 28/87 (32%), Positives = 38/87 (43%)
Query: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
F C C P++ + +DG C + C C PI A + WHDT
Sbjct: 394 FVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDT 453
Query: 81 CFRCAKCLHPLANETFVAKDNKILCNK 107
CF C+ C L +TF +K +K LC K
Sbjct: 454 CFVCSVCCESLEGQTFFSKKDKPLCKK 480
Score = 35.4 bits (80), Expect = 0.061
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
CA C I +G +VA G+SWH F+C C +A FV + +YC C +K
Sbjct: 311 CAHCNQVI----RGPFLVAL-GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEK 364
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.137 0.488
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,314,678
Number of Sequences: 37866
Number of extensions: 677741
Number of successful extensions: 7136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 612
Number of HSP's that attempted gapping in prelim test: 2515
Number of HSP's gapped (non-prelim): 2367
length of query: 296
length of database: 18,247,518
effective HSP length: 102
effective length of query: 194
effective length of database: 14,385,186
effective search space: 2790726084
effective search space used: 2790726084
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.