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Search of human proteins with 228008398
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 3 [Homo sapiens]
(527 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting ... 1082 0.0
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ... 1064 0.0
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ... 1058 0.0
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ... 1056 0.0
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ... 1038 0.0
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ... 873 0.0
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 834 0.0
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 829 0.0
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 699 0.0
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 694 0.0
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens] 303 2e-82
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens] 288 1e-77
gi|20357575 apobec-1 complementation factor isoform 2 [Homo sapi... 285 9e-77
gi|20357572 apobec-1 complementation factor isoform 1 [Homo sapi... 285 9e-77
gi|21450675 RNA binding motif protein 46 [Homo sapiens] 282 5e-76
gi|20357578 apobec-1 complementation factor isoform 3 [Homo sapi... 268 9e-72
gi|34740339 dead end homolog 1 [Homo sapiens] 123 4e-28
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 91 3e-18
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 83 7e-16
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 83 7e-16
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 83 7e-16
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa... 81 3e-15
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 77 5e-14
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ... 74 3e-13
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens] 74 3e-13
gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a ... 74 4e-13
gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s... 73 6e-13
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s... 73 7e-13
gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa... 73 7e-13
gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens] 72 1e-12
>gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 3 [Homo sapiens]
Length = 527
Score = 1082 bits (2798), Expect = 0.0
Identities = 527/527 (100%), Positives = 527/527 (100%)
Query: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
Query: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
Query: 301 QVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKD 360
QVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKD
Sbjct: 301 QVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKD 360
Query: 361 LEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYG 420
LEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYG
Sbjct: 361 LEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYG 420
Query: 421 YPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAA 480
YPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAA
Sbjct: 421 YPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAA 480
Query: 481 PPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ 527
PPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ
Sbjct: 481 PPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ 527
>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 6 [Homo sapiens]
Length = 562
Score = 1064 bits (2752), Expect = 0.0
Identities = 527/562 (93%), Positives = 527/562 (93%), Gaps = 35/562 (6%)
Query: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
Query: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
Query: 301 Q-----------------------------------VKVLFVRNLANTVTEEILEKAFSQ 325
Q VKVLFVRNLANTVTEEILEKAFSQ
Sbjct: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
Query: 326 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 385
FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR
Sbjct: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
Query: 386 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 445
QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG
Sbjct: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480
Query: 446 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 505
YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG
Sbjct: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540
Query: 506 GAQQQRGRGQGKGVEAGPDLLQ 527
GAQQQRGRGQGKGVEAGPDLLQ
Sbjct: 541 GAQQQRGRGQGKGVEAGPDLLQ 562
>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 5 [Homo sapiens]
Length = 561
Score = 1058 bits (2735), Expect = 0.0
Identities = 526/562 (93%), Positives = 526/562 (93%), Gaps = 36/562 (6%)
Query: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
Query: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
Query: 301 Q-----------------------------------VKVLFVRNLANTVTEEILEKAFSQ 325
Q VKVLFVRNLANTVTEEILEKAFSQ
Sbjct: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
Query: 326 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 385
FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR
Sbjct: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
Query: 386 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 445
QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG
Sbjct: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480
Query: 446 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 505
YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG
Sbjct: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540
Query: 506 GAQQQRGRGQGKGVEAGPDLLQ 527
GAQQQRGRG GKGVEAGPDLLQ
Sbjct: 541 GAQQQRGRG-GKGVEAGPDLLQ 561
>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 4 [Homo sapiens]
Length = 588
Score = 1056 bits (2731), Expect = 0.0
Identities = 514/514 (100%), Positives = 514/514 (100%)
Query: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
Query: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
Query: 301 QVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKD 360
QVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKD
Sbjct: 301 QVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKD 360
Query: 361 LEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYG 420
LEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYG
Sbjct: 361 LEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYG 420
Query: 421 YPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAA 480
YPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAA
Sbjct: 421 YPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAA 480
Query: 481 PPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRG 514
PPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRG
Sbjct: 481 PPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRG 514
>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 1 [Homo sapiens]
Length = 623
Score = 1038 bits (2685), Expect = 0.0
Identities = 514/549 (93%), Positives = 514/549 (93%), Gaps = 35/549 (6%)
Query: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
Query: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
Query: 301 Q-----------------------------------VKVLFVRNLANTVTEEILEKAFSQ 325
Q VKVLFVRNLANTVTEEILEKAFSQ
Sbjct: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
Query: 326 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 385
FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR
Sbjct: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
Query: 386 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 445
QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG
Sbjct: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480
Query: 446 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 505
YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG
Sbjct: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540
Query: 506 GAQQQRGRG 514
GAQQQRGRG
Sbjct: 541 GAQQQRGRG 549
>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 2 [Homo sapiens]
Length = 464
Score = 873 bits (2256), Expect = 0.0
Identities = 429/464 (92%), Positives = 429/464 (92%), Gaps = 35/464 (7%)
Query: 99 MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP 158
MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP
Sbjct: 1 MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP 60
Query: 159 SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 218
SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE
Sbjct: 61 SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 120
Query: 219 AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQ 278
AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQ
Sbjct: 121 AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQ 180
Query: 279 PDDKKKNRGFCFLEYEDHKTAAQ-----------------------------------VK 303
PDDKKKNRGFCFLEYEDHKTAAQ VK
Sbjct: 181 PDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVK 240
Query: 304 VLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEG 363
VLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEG
Sbjct: 241 VLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEG 300
Query: 364 ENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPP 423
ENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPP
Sbjct: 301 ENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPP 360
Query: 424 DYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPR 483
DYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPR
Sbjct: 361 DYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPR 420
Query: 484 GRAGYSQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ 527
GRAGYSQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ
Sbjct: 421 GRAGYSQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ 464
>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
[Homo sapiens]
Length = 633
Score = 834 bits (2155), Expect = 0.0
Identities = 422/555 (76%), Positives = 469/555 (84%), Gaps = 48/555 (8%)
Query: 6 VNGNGT-----EEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
VNGN EEPMDT+S V H+E+++TL++AGLPQKVAE+LDEI+ GLVA+ DLDER
Sbjct: 5 VNGNAVQLKEEEEPMDTSS-VTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDER 63
Query: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
AI+AL+EFNE+GAL+VLQQFK+SDLSHVQNKSAFLCGVMKTYRQREKQG+KV +S+KGPD
Sbjct: 64 AIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPD 123
Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSG QP +GTE+FVGKIPRDL+EDELVP
Sbjct: 124 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 183
Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
LFEKAGPIWDLRLMMDPL+G NRGYAF+TFC KEAAQEAVKL +++EIR GKH+GVCISV
Sbjct: 184 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 243
Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
ANNRLFVGSIPK+KTKE ILEEFSKVTEGL DVILYHQPDDKKKNRGFCFLEYEDHK+AA
Sbjct: 244 ANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAA 303
Query: 301 Q-----------------------------------VKVLFVRNLANTVTEEILEKAFSQ 325
Q VKVLFVRNLA TVTEEILEK+FS+
Sbjct: 304 QARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSE 363
Query: 326 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 385
FGKLERVKKLKDYAF+HF++R AVKAM+EMNGK++EGE IEIV AKPPD+KRKER+A R
Sbjct: 364 FGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAAR 423
Query: 386 QAAKNQMYDDYYYYGPPHMPPPTRGRGR-GGRGGYGYPPDYYGYEDYY-DYYGYDYHNYR 443
QA+++ Y+DYYY+ PP MPPP RGRGR GGRGGYGYPPDYYGYEDYY DYYGYDYH+YR
Sbjct: 424 QASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYR 483
Query: 444 GGYEDPYYGYED-FQVGARGRGGRGARGA-APSRGRGAAPPRGRAGYSQRGGP-GSARGV 500
GGYEDPYYGY+D + V RG GGRG RGA P RGRGA PPRGRAGYSQRG P G RG
Sbjct: 484 GGYEDPYYGYDDGYAVRGRG-GGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGS 542
Query: 501 RGARGG-AQQQRGRG 514
RG RGG AQQQRGRG
Sbjct: 543 RGGRGGPAQQQRGRG 557
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 829 bits (2141), Expect = 0.0
Identities = 422/558 (75%), Positives = 469/558 (84%), Gaps = 51/558 (9%)
Query: 6 VNGNGT-----EEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
VNGN EEPMDT+S V H+E+++TL++AGLPQKVAE+LDEI+ GLVA+ DLDER
Sbjct: 5 VNGNAVQLKEEEEPMDTSS-VTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDER 63
Query: 61 AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
AI+AL+EFNE+GAL+VLQQFK+SDLSHVQNKSAFLCGVMKTYRQREKQG+KV +S+KGPD
Sbjct: 64 AIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPD 123
Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSG QP +GTE+FVGKIPRDL+EDELVP
Sbjct: 124 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 183
Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
LFEKAGPIWDLRLMMDPL+G NRGYAF+TFC KEAAQEAVKL +++EIR GKH+GVCISV
Sbjct: 184 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 243
Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKV---TEGLTDVILYHQPDDKKKNRGFCFLEYEDHK 297
ANNRLFVGSIPK+KTKE ILEEFSKV TEGL DVILYHQPDDKKKNRGFCFLEYEDHK
Sbjct: 244 ANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 303
Query: 298 TAAQ-----------------------------------VKVLFVRNLANTVTEEILEKA 322
+AAQ VKVLFVRNLA TVTEEILEK+
Sbjct: 304 SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS 363
Query: 323 FSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 382
FS+FGKLERVKKLKDYAF+HF++R AVKAM+EMNGK++EGE IEIV AKPPD+KRKER+
Sbjct: 364 FSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQ 423
Query: 383 AQRQAAKNQMYDDYYYYGPPHMPPPTRGRGR-GGRGGYGYPPDYYGYEDYY-DYYGYDYH 440
A RQA+++ Y+DYYY+ PP MPPP RGRGR GGRGGYGYPPDYYGYEDYY DYYGYDYH
Sbjct: 424 AARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH 483
Query: 441 NYRGGYEDPYYGYED-FQVGARGRGGRGARGA-APSRGRGAAPPRGRAGYSQRGGP-GSA 497
+YRGGYEDPYYGY+D + V RG GGRG RGA P RGRGA PPRGRAGYSQRG P G
Sbjct: 484 DYRGGYEDPYYGYDDGYAVRGRG-GGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPP 542
Query: 498 RGVRGARGG-AQQQRGRG 514
RG RG RGG AQQQRGRG
Sbjct: 543 RGSRGGRGGPAQQQRGRG 560
>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
[Homo sapiens]
Length = 532
Score = 699 bits (1805), Expect = 0.0
Identities = 351/457 (76%), Positives = 383/457 (83%), Gaps = 42/457 (9%)
Query: 99 MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP 158
MKTYRQREKQG+KV +S+KGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSG QP
Sbjct: 1 MKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQP 60
Query: 159 SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 218
+GTE+FVGKIPRDL+EDELVPLFEKAGPIWDLRLMMDPL+G NRGYAF+TFC KEAAQE
Sbjct: 61 GIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQE 120
Query: 219 AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQ 278
AVKL +++EIR GKH+GVCISVANNRLFVGSIPK+KTKE ILEEFSKVTEGL DVILYHQ
Sbjct: 121 AVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQ 180
Query: 279 PDDKKKNRGFCFLEYEDHKTAAQ-----------------------------------VK 303
PDDKKKNRGFCFLEYEDHK+AAQ VK
Sbjct: 181 PDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVK 240
Query: 304 VLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEG 363
VLFVRNLA TVTEEILEK+FS+FGKLERVKKLKDYAF+HF++R AVKAM+EMNGK++EG
Sbjct: 241 VLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEG 300
Query: 364 ENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGR-GGRGGYGYP 422
E IEIV AKPPD+KRKER+A RQA+++ Y+DYYY+ PP MPPP RGRGR GGRGGYGYP
Sbjct: 301 EEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYP 360
Query: 423 PDYYGYEDYY-DYYGYDYHNYRGGYEDPYYGYED-FQVGARGRGGRGARGA-APSRGRGA 479
PDYYGYEDYY DYYGYDYH+YRGGYEDPYYGY+D + V RG GGRG RGA P RGRGA
Sbjct: 361 PDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRG-GGRGGRGAPPPPRGRGA 419
Query: 480 APPRGRAGYSQRGGP-GSARGVRGARGG-AQQQRGRG 514
PPRGRAGYSQRG P G RG RG RGG AQQQRGRG
Sbjct: 420 PPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 456
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 694 bits (1791), Expect = 0.0
Identities = 351/460 (76%), Positives = 383/460 (83%), Gaps = 45/460 (9%)
Query: 99 MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP 158
MKTYRQREKQG+KV +S+KGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSG QP
Sbjct: 1 MKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQP 60
Query: 159 SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 218
+GTE+FVGKIPRDL+EDELVPLFEKAGPIWDLRLMMDPL+G NRGYAF+TFC KEAAQE
Sbjct: 61 GIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQE 120
Query: 219 AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKV---TEGLTDVIL 275
AVKL +++EIR GKH+GVCISVANNRLFVGSIPK+KTKE ILEEFSKV TEGL DVIL
Sbjct: 121 AVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVIL 180
Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQ---------------------------------- 301
YHQPDDKKKNRGFCFLEYEDHK+AAQ
Sbjct: 181 YHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMA 240
Query: 302 -VKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKD 360
VKVLFVRNLA TVTEEILEK+FS+FGKLERVKKLKDYAF+HF++R AVKAM+EMNGK+
Sbjct: 241 KVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKE 300
Query: 361 LEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGR-GGRGGY 419
+EGE IEIV AKPPD+KRKER+A RQA+++ Y+DYYY+ PP MPPP RGRGR GGRGGY
Sbjct: 301 IEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGY 360
Query: 420 GYPPDYYGYEDYY-DYYGYDYHNYRGGYEDPYYGYED-FQVGARGRGGRGARGA-APSRG 476
GYPPDYYGYEDYY DYYGYDYH+YRGGYEDPYYGY+D + V RG GGRG RGA P RG
Sbjct: 361 GYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRG-GGRGGRGAPPPPRG 419
Query: 477 RGAAPPRGRAGYSQRGGP-GSARGVRGARGG-AQQQRGRG 514
RGA PPRGRAGYSQRG P G RG RG RGG AQQQRGRG
Sbjct: 420 RGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 459
>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
Length = 593
Score = 303 bits (777), Expect = 2e-82
Identities = 195/455 (42%), Positives = 252/455 (55%), Gaps = 86/455 (18%)
Query: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
KV + G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G E+FVGKI
Sbjct: 21 KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78
Query: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
PRD++EDELVP+FE G I++LRLMMD G NRGYAFV +C K A+ AV+ NN+EIR
Sbjct: 79 PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
Query: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y DK KNRGF
Sbjct: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
Query: 290 FLEYEDHKTAAQ-----------------------------------VKVLFVRNLANTV 314
F+EYE H+ AA VK+L+VRNL
Sbjct: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
Query: 315 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 372
TE+ ++K+F QF G +ERVKK++DYAF+HF R+ AV AM +NG +LEG +E+ AK
Sbjct: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
Query: 373 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 431
P D KE+ ++ Q A RG G P Y + Y
Sbjct: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353
Query: 432 YDYYGYDYHNYRGGYEDPYYGYEDFQVGA-RGRGGRGARGAAPSRGRGAAPPRGRAGYSQ 490
YYGY Y+ G D + + G+ RGRG RGAA +R G PRG S
Sbjct: 354 LAYYGYPYNALIGPNRDYF-----VKAGSIRGRG----RGAAGNRAPG---PRG----SY 397
Query: 491 RGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDL 525
GG + RG+ + +G+ Q KG E P+L
Sbjct: 398 LGGYSAGRGIYSR---YHEGKGKQQEKGYELVPNL 429
>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
Length = 524
Score = 288 bits (736), Expect = 1e-77
Identities = 171/390 (43%), Positives = 221/390 (56%), Gaps = 66/390 (16%)
Query: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
KV + G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G E+FVGKI
Sbjct: 21 KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78
Query: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
PRD++EDELVP+FE G I++LRLMMD G NRGYAFV +C K A+ AV+ NN+EIR
Sbjct: 79 PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
Query: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y DK KNRGF
Sbjct: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
Query: 290 FLEYEDHKTAAQ-----------------------------------VKVLFVRNLANTV 314
F+EYE H+ AA VK+L+VRNL
Sbjct: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
Query: 315 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 372
TE+ ++K+F QF G +ERVKK++DYAF+HF R+ AV AM +NG +LEG +E+ AK
Sbjct: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
Query: 373 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 431
P D KE+ ++ Q A RG G P Y + Y
Sbjct: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353
Query: 432 YDYYGYDYHNYRGGYEDPYYGYEDFQVGAR 461
YYGY Y+ G D + +GA+
Sbjct: 354 LAYYGYPYNALIGPNRDYFVKVAIPAIGAQ 383
>gi|20357575 apobec-1 complementation factor isoform 2 [Homo
sapiens]
Length = 594
Score = 285 bits (728), Expect = 9e-77
Identities = 172/417 (41%), Positives = 228/417 (54%), Gaps = 59/417 (14%)
Query: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
K G ++ + K EA ++AL++RTGY+L GQRKYGGPPP + P G EIF+
Sbjct: 6 KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
Query: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
GK+PRDLFEDEL+PL EK G I+++R+MMD G NRGYAFVTF K A+ A+K NN+
Sbjct: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
Query: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E KVTEG+ DVI+Y DK KNR
Sbjct: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
Query: 287 GFCFLEYEDHKTAA-----------------------------------QVKVLFVRNLA 311
GF F+EYE H+ AA VK+L+VRNL
Sbjct: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
Query: 312 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 369
+ +EE++EK F+ G +ERVKK++DYAF+HF R+ AV+AM+ +NGK L+G IE+
Sbjct: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
Query: 370 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 429
AKP D+ R + + M Y Y + PT Y P +Y +
Sbjct: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
Query: 430 DYYDYYGYDYHNYRGGYEDPYY--------GYEDFQVGARGRGGRGARGAAPSRGRG 478
Y + +G + Y + VGA G G G RG G G
Sbjct: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLG 408
>gi|20357572 apobec-1 complementation factor isoform 1 [Homo
sapiens]
Length = 586
Score = 285 bits (728), Expect = 9e-77
Identities = 170/409 (41%), Positives = 225/409 (55%), Gaps = 51/409 (12%)
Query: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
K G ++ + K EA ++AL++RTGY+L GQRKYGGPPP + P G EIF+
Sbjct: 6 KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
Query: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
GK+PRDLFEDEL+PL EK G I+++R+MMD G NRGYAFVTF K A+ A+K NN+
Sbjct: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
Query: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E KVTEG+ DVI+Y DK KNR
Sbjct: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
Query: 287 GFCFLEYEDHKTAA-----------------------------------QVKVLFVRNLA 311
GF F+EYE H+ AA VK+L+VRNL
Sbjct: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
Query: 312 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 369
+ +EE++EK F+ G +ERVKK++DYAF+HF R+ AV+AM+ +NGK L+G IE+
Sbjct: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
Query: 370 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 429
AKP D+ R + + M Y Y + PT Y P +Y +
Sbjct: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
Query: 430 DYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRG 478
Y + +G + GA G G G RG G G
Sbjct: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLG 400
>gi|21450675 RNA binding motif protein 46 [Homo sapiens]
Length = 533
Score = 282 bits (722), Expect = 5e-76
Identities = 149/300 (49%), Positives = 199/300 (66%), Gaps = 40/300 (13%)
Query: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179
+EA + AL+E+TGY + GQRK+GGPPP + G P G E+FVGKIPRD++EDELV
Sbjct: 21 NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
Query: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239
P+FE+AG I++ RLMM+ +G NRGYAFV + TKE AQ A+++ NN+EIR GK IGVC+S
Sbjct: 79 PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
Query: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299
+ N RLF+G+IPK K KE+IL+E KVTEG+ DVI+Y DK KNRGF F+EYE H+ A
Sbjct: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
Query: 300 A-----------------------------------QVKVLFVRNLANTVTEEILEKAFS 324
A +VKVL+VRNL + TEE ++ F+
Sbjct: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
Query: 325 QF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 382
+F G +ERVKKL+DYAF+HF R+ AV AM MNGK ++G +IE+ AKP +++ R+
Sbjct: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
>gi|20357578 apobec-1 complementation factor isoform 3 [Homo
sapiens]
Length = 594
Score = 268 bits (685), Expect = 9e-72
Identities = 159/381 (41%), Positives = 207/381 (54%), Gaps = 48/381 (12%)
Query: 135 LDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 194
L+ GQRKYGGPPP + P G EIF+GK+PRDLFEDEL+PL EK G I+++R+M
Sbjct: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
Query: 195 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSK 254
MD G NRGYAFVTF K A+ A+K NN+EIR+G+ +GVC SV N RLFVG IPK+K
Sbjct: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
Query: 255 TKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA-------------- 300
+E+IL E KVTEG+ DVI+Y DK KNRGF F+EYE H+ AA
Sbjct: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
Query: 301 ---------------------QVKVLFVRNLANTVTEEILEKAFSQF--GKLERVKKLKD 337
VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
Query: 338 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYY 397
YAF+HF R+ AV+AM+ +NGK L+G IE+ AKP D+ R + + M Y
Sbjct: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
Query: 398 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQ 457
Y + PT Y P +Y + Y + +G +
Sbjct: 336 TYSLGQVYDPTT--------TYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSV 387
Query: 458 VGARGRGGRGARGAAPSRGRG 478
GA G G G RG G G
Sbjct: 388 RGAAGVRGLGGRGYLAYTGLG 408
>gi|34740339 dead end homolog 1 [Homo sapiens]
Length = 353
Score = 123 bits (309), Expect = 4e-28
Identities = 65/199 (32%), Positives = 108/199 (54%), Gaps = 5/199 (2%)
Query: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179
++A ++A + TG L GQRKYGGPPP V G P G+E+F+G++P+D++E +L+
Sbjct: 18 NKAALEAWVRETGIRLVQVNGQRKYGGPPPGWV--GSPPPAGSEVFIGRLPQDVYEHQLI 75
Query: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239
PLF++ G +++ RLMM +GLNRG+A+ + ++ AQ A+ +NH +R + VC S
Sbjct: 76 PLFQRVGRLYEFRLMM-TFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRS 134
Query: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299
L V +P + T+ +L + GL + L P L++ H+ A
Sbjct: 135 TEKCELSVDGLPPNLTRSALLLALQPLGPGLQEARLLPSPGPAPGQ--IALLKFSSHRAA 192
Query: 300 AQVKVLFVRNLANTVTEEI 318
A K V ++ E++
Sbjct: 193 AMAKKALVEGQSHLCGEQV 211
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 90.9 bits (224), Expect = 3e-18
Identities = 69/282 (24%), Positives = 126/282 (44%), Gaps = 64/282 (22%)
Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
++VG + D+ ED L F GP+ +R+ D +T + GYA+V F AQ+A+
Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
Query: 224 NNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
N +I GK I + S + +F+ ++ KS + + E FS + L+ ++
Sbjct: 72 N-FDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
Query: 276 YHQPDDKKKNRGFCFLEYEDHKTA------------------------------------ 299
D + ++G+ F+ +++ A
Sbjct: 131 ----SDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKA 186
Query: 300 AQVKVLFVRNLANTVTEEILEKAFSQFGKLERVK-------KLKDYAFIHFDERDGAVKA 352
++ ++++N + +E L+ FS++GK VK K K + F+ FD + A KA
Sbjct: 187 SEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKA 246
Query: 353 MEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYD 394
+EEMNG+D+ G+ I + R ++K +RQA QM++
Sbjct: 247 VEEMNGRDINGQLIFV--------GRAQKKVERQAELKQMFE 280
Score = 71.2 bits (173), Expect = 2e-12
Identities = 55/217 (25%), Positives = 99/217 (45%), Gaps = 44/217 (20%)
Query: 162 TEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVK 221
T +++ D+ ++ L +F K G +++M D +G ++G+ FV+F + EAA++AV+
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
Query: 222 LYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDD 281
N +I +FVG K ++ L++ + +
Sbjct: 249 EMNGRDIN------------GQLIFVGRAQKKVERQAELKQMFEQLK------------- 283
Query: 282 KKKNRGFCFLEYEDHKTAAQVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKL------ 335
+++ RG Q L+++NL +T+ +E L FS FG + RVK +
Sbjct: 284 RERIRG------------CQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQS 331
Query: 336 KDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 372
K + I F + A KAM EMNG+ L + + I A+
Sbjct: 332 KGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 82.8 bits (203), Expect = 7e-16
Identities = 68/284 (23%), Positives = 128/284 (45%), Gaps = 56/284 (19%)
Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
++VG + D+ E L F AGP+ +R+ D +T + GYA+V F A+ A+
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 224 NNHEIRSGKHIGVCISVANNRL--------FVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
N ++ GK I + S + L F+ ++ KS + + + FS L+ ++
Sbjct: 73 N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQV------------KV------------------- 304
D+ ++G+ F+ +E + A + KV
Sbjct: 132 C----DENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA 187
Query: 305 -----LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAVKA 352
++++N V +E L++ FSQFGK VK ++D + F+ +++ + A KA
Sbjct: 188 KEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKA 247
Query: 353 MEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDY 396
+EEMNGK++ G+ I + A+ +++ E K + + K + Y
Sbjct: 248 VEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRY 291
Score = 69.7 bits (169), Expect = 6e-12
Identities = 73/308 (23%), Positives = 131/308 (42%), Gaps = 80/308 (25%)
Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
G P ++S + PS+ +F+ + + + L F G I +++ D
Sbjct: 79 GKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136
Query: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247
++GYAFV F T+EAA +A++ L N+ ++ G+ +G N +++
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTN-VYI 195
Query: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA-------- 299
+ + E + E FS+ + L+ ++ D K++GF F+ YE H+ A
Sbjct: 196 KNFGEEVDDESLKELFSQFGKTLSVKVMR---DPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 300 -------------AQVKV-------------------------LFVRNLANTVTEEILEK 321
AQ KV L+++NL +T+ +E L K
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 322 AFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPD 375
FS FG + K + K + F+ F + A KA+ EMNG+ + + + + A
Sbjct: 313 EFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA---- 368
Query: 376 QKRKERKA 383
Q+++ERKA
Sbjct: 369 QRKEERKA 376
Score = 39.7 bits (91), Expect = 0.007
Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
L+V +L + VTE +L + FS G + ++ +D YA+++F + A +A++ M
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 357 NGKDLEGENIEIVFAKPPDQKRKE-------RKAQRQAAKNQMYDDYYYYG 400
N ++G+ I I++++ RK + + +YD + +G
Sbjct: 73 NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFG 123
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 82.8 bits (203), Expect = 7e-16
Identities = 68/284 (23%), Positives = 128/284 (45%), Gaps = 56/284 (19%)
Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
++VG + D+ E L F AGP+ +R+ D +T + GYA+V F A+ A+
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 224 NNHEIRSGKHIGVCISVANNRL--------FVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
N ++ GK I + S + L F+ ++ KS + + + FS L+ ++
Sbjct: 73 N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQV------------KV------------------- 304
D+ ++G+ F+ +E + A + KV
Sbjct: 132 C----DENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA 187
Query: 305 -----LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAVKA 352
++++N V +E L++ FSQFGK VK ++D + F+ +++ + A KA
Sbjct: 188 KEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKA 247
Query: 353 MEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDY 396
+EEMNGK++ G+ I + A+ +++ E K + + K + Y
Sbjct: 248 VEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRY 291
Score = 69.7 bits (169), Expect = 6e-12
Identities = 73/308 (23%), Positives = 131/308 (42%), Gaps = 80/308 (25%)
Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
G P ++S + PS+ +F+ + + + L F G I +++ D
Sbjct: 79 GKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136
Query: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247
++GYAFV F T+EAA +A++ L N+ ++ G+ +G N +++
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTN-VYI 195
Query: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA-------- 299
+ + E + E FS+ + L+ ++ D K++GF F+ YE H+ A
Sbjct: 196 KNFGEEVDDESLKELFSQFGKTLSVKVMR---DPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 300 -------------AQVKV-------------------------LFVRNLANTVTEEILEK 321
AQ KV L+++NL +T+ +E L K
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 322 AFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPD 375
FS FG + K + K + F+ F + A KA+ EMNG+ + + + + A
Sbjct: 313 EFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA---- 368
Query: 376 QKRKERKA 383
Q+++ERKA
Sbjct: 369 QRKEERKA 376
Score = 39.7 bits (91), Expect = 0.007
Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
L+V +L + VTE +L + FS G + ++ +D YA+++F + A +A++ M
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 357 NGKDLEGENIEIVFAKPPDQKRKE-------RKAQRQAAKNQMYDDYYYYG 400
N ++G+ I I++++ RK + + +YD + +G
Sbjct: 73 NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFG 123
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 82.8 bits (203), Expect = 7e-16
Identities = 68/284 (23%), Positives = 128/284 (45%), Gaps = 56/284 (19%)
Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
++VG + D+ E L F AGP+ +R+ D +T + GYA+V F A+ A+
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 224 NNHEIRSGKHIGVCISVANNRL--------FVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
N ++ GK I + S + L F+ ++ KS + + + FS L+ ++
Sbjct: 73 N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQV------------KV------------------- 304
D+ ++G+ F+ +E + A + KV
Sbjct: 132 C----DENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA 187
Query: 305 -----LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAVKA 352
++++N V +E L++ FSQFGK VK ++D + F+ +++ + A KA
Sbjct: 188 KEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKA 247
Query: 353 MEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDY 396
+EEMNGK++ G+ I + A+ +++ E K + + K + Y
Sbjct: 248 VEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRY 291
Score = 69.7 bits (169), Expect = 6e-12
Identities = 73/308 (23%), Positives = 131/308 (42%), Gaps = 80/308 (25%)
Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
G P ++S + PS+ +F+ + + + L F G I +++ D
Sbjct: 79 GKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136
Query: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247
++GYAFV F T+EAA +A++ L N+ ++ G+ +G N +++
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTN-VYI 195
Query: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA-------- 299
+ + E + E FS+ + L+ ++ D K++GF F+ YE H+ A
Sbjct: 196 KNFGEEVDDESLKELFSQFGKTLSVKVMR---DPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 300 -------------AQVKV-------------------------LFVRNLANTVTEEILEK 321
AQ KV L+++NL +T+ +E L K
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 322 AFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPD 375
FS FG + K + K + F+ F + A KA+ EMNG+ + + + + A
Sbjct: 313 EFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA---- 368
Query: 376 QKRKERKA 383
Q+++ERKA
Sbjct: 369 QRKEERKA 376
Score = 39.7 bits (91), Expect = 0.007
Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
L+V +L + VTE +L + FS G + ++ +D YA+++F + A +A++ M
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 357 NGKDLEGENIEIVFAKPPDQKRKE-------RKAQRQAAKNQMYDDYYYYG 400
N ++G+ I I++++ RK + + +YD + +G
Sbjct: 73 NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFG 123
>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
sapiens]
Length = 485
Score = 80.9 bits (198), Expect = 3e-15
Identities = 50/168 (29%), Positives = 88/168 (52%), Gaps = 12/168 (7%)
Query: 145 GGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRG 204
G PP G + ++FVG+IPR L E +L PLFE+ G I++L ++ DP TG+++G
Sbjct: 28 GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
Query: 205 YAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN--------RLFVGSIPKSKTK 256
AF+T+C +++A +A + + G + + A++ +LFVG + K +++
Sbjct: 88 CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
Query: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQVKV 304
E +L F + + + PD K G F+++ H T AQ +
Sbjct: 148 EDVLRLFQPFGV-IDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAI 191
Score = 42.4 bits (98), Expect = 0.001
Identities = 22/82 (26%), Positives = 41/82 (50%)
Query: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206
PPP ++ G +F+ +P++ + EL +F G I ++ MD T ++ +
Sbjct: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
Query: 207 FVTFCTKEAAQEAVKLYNNHEI 228
FV+F +AQ A++ N +I
Sbjct: 445 FVSFDNPASAQAAIQAMNGFQI 466
Score = 33.1 bits (74), Expect = 0.64
Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LFV + + E+ L+ F QFG++ + LKD AF+ + RD A+KA +
Sbjct: 47 LFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTAL 106
Query: 357 NGKDLEGENIEIVFAKPPDQKRK 379
+ + + KP D + +
Sbjct: 107 HEQKTLPGMARPIQVKPADSESR 129
Score = 30.4 bits (67), Expect = 4.2
Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 8/79 (10%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LF+ +L + L + F FG + K D + F+ FD A A++ M
Sbjct: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
Query: 357 NGKDLEGENIEIVFAKPPD 375
NG + + +++ +P D
Sbjct: 462 NGFQIGMKRLKVQLKRPKD 480
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 76.6 bits (187), Expect = 5e-14
Identities = 42/144 (29%), Positives = 81/144 (56%), Gaps = 10/144 (6%)
Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
++F+G+IPR+L E +L PLFE+ G I++L ++ D TG+++G AF+T+C +E+A +A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 223 YNNHEIRSGKHIGVCISVANN-------RLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
+ + G + + + A++ +LFVG + K ++++ + F + + + +
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLF-EAFGNIEECTI 173
Query: 276 YHQPDDKKKNRGFCFLEYEDHKTA 299
PD K G F++Y H A
Sbjct: 174 LRGPDGNSK--GCAFVKYSSHAEA 195
Score = 35.8 bits (81), Expect = 0.099
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 10/84 (11%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LF+ + + E+ L+ F +FGK+ + LKD AF+ + ER+ A+KA +
Sbjct: 56 LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
Query: 357 N-GKDLEGENIEIVFAKPPDQKRK 379
+ K L G N I KP D + +
Sbjct: 116 HEQKTLPGMNRPIQ-VKPADSESR 138
>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
[Homo sapiens]
Length = 336
Score = 74.3 bits (181), Expect = 3e-13
Identities = 87/367 (23%), Positives = 137/367 (37%), Gaps = 69/367 (18%)
Query: 110 TKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEI----- 164
T S G E + A + G +G GG G S G +I
Sbjct: 16 TAAVGGSAGEQEGAMVAATQ--GAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKN 73
Query: 165 -------FVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQ 217
F+G + D + +L F K G + D L +DP+TG +RG+ FV F E+
Sbjct: 74 EEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVD 133
Query: 218 EAVKLYNNHEIRSGKHIGVCISVAN------NRLFVGSIPKSKTKEQILEEFSKVTEGLT 271
+ + H++ +GK I + A ++FVG + +E+I E F G
Sbjct: 134 KVMD-QKEHKL-NGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFG----GFG 187
Query: 272 DVILYHQPDDKK--KNRGFCFLEYEDHKTAAQVKVLFVRNLANTVTEEILEKAFSQFGKL 329
+V P D K K RGFCF+ +++ + ++ N+ + E + + Q+ +
Sbjct: 188 EVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQ 247
Query: 330 ERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAK 389
++ + R G G + N Q
Sbjct: 248 QQ-----------WGSRGGFAGRARGRGGGPSQNWN--------------------QGYS 276
Query: 390 NQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYP--PDYYGYEDYYDYY-GYDYHNYRGGY 446
N Y YG +G GG GGY Y +YYGY DY + GY + RGG+
Sbjct: 277 NYWNQGYGNYG-------YNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGH 329
Query: 447 EDPYYGY 453
++ Y Y
Sbjct: 330 QNSYKPY 336
Score = 58.5 bits (140), Expect = 1e-08
Identities = 67/276 (24%), Positives = 106/276 (38%), Gaps = 76/276 (27%)
Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDH------- 296
++F+G + TK+ + + FSK E + D L P + +RGF F+ +++
Sbjct: 79 KMFIGGLSWDTTKKDLKDYFSKFGE-VVDCTLKLDPITGR-SRGFGFVLFKESESVDKVM 136
Query: 297 --------------------KTAAQVKVLFVRNLANTVTEEILEKAFSQFGKLERVK--- 333
KT VK +FV L+ EE + + F FG++E ++
Sbjct: 137 DQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPM 196
Query: 334 -----KLKDYAFIHFDERDGAVKAMEEM-NGKDLEGENIEIVFAKPPDQKRKERKAQRQA 387
K + + FI F E + K ME+ + L I++ +K Q++++ ++
Sbjct: 197 DNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGF 256
Query: 388 AK-------------NQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDY 434
A NQ Y +Y+ G G YGY YG Y
Sbjct: 257 AGRARGRGGGPSQNWNQGYSNYW---------------NQGYGNYGYNSQGYG-----GY 296
Query: 435 YGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARG 470
GYDY Y YYGY D+ G G RG
Sbjct: 297 GGYDYTGYNN-----YYGYGDYSNQQSGYGKVSRRG 327
>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
Length = 465
Score = 74.3 bits (181), Expect = 3e-13
Identities = 43/144 (29%), Positives = 80/144 (55%), Gaps = 10/144 (6%)
Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
++FVG+IPR L E +L P+FE+ G I++L ++ D TGL++G AF+T+C +++A +A
Sbjct: 8 KLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSA 67
Query: 223 YNNHEIRSGKHIGVCISVANN-------RLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
+ + G + + + A++ +LFVG + K +T E + + F + + +
Sbjct: 68 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGT-IDECTV 126
Query: 276 YHQPDDKKKNRGFCFLEYEDHKTA 299
PD K G F++++ H A
Sbjct: 127 LRGPDGTSK--GCAFVKFQTHAEA 148
Score = 33.5 bits (75), Expect = 0.49
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 10/84 (11%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LFV + + E+ L+ F QFG++ + +KD AF+ + RD A+KA +
Sbjct: 9 LFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSAL 68
Query: 357 N-GKDLEGENIEIVFAKPPDQKRK 379
+ K L G N I KP D + +
Sbjct: 69 HEQKTLPGMNRPIQ-VKPADSESR 91
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/82 (23%), Positives = 36/82 (43%), Gaps = 8/82 (9%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
+F+ +L T+ + + F FG + K D + F+ FD A A++ M
Sbjct: 382 IFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAM 441
Query: 357 NGKDLEGENIEIVFAKPPDQKR 378
NG + + +++ +P D R
Sbjct: 442 NGFQIGMKRLKVQLKRPKDANR 463
>gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a
[Homo sapiens]
Length = 355
Score = 73.6 bits (179), Expect = 4e-13
Identities = 74/302 (24%), Positives = 122/302 (40%), Gaps = 55/302 (18%)
Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
++F+G + D + +L F K G + D L +DP+TG +RG+ FV F E+ + +
Sbjct: 98 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMD- 156
Query: 223 YNNHEIRSGKHIGVCISVAN------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILY 276
H++ +GK I + A ++FVG + +E+I E F G +V
Sbjct: 157 QKEHKL-NGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFG----GFGEVESI 211
Query: 277 HQPDDKK--KNRGFCFLEYEDHKTAAQVKVLFVRNLANTVTEEILEKAFSQFGKLERVKK 334
P D K K RGFCF+ +++ + ++ N+ + E + + Q+ + ++
Sbjct: 212 ELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQ--- 268
Query: 335 LKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYD 394
+ R G G + N Q N
Sbjct: 269 --------WGSRGGFAGRARGRGGGPSQNWN--------------------QGYSNYWNQ 300
Query: 395 DYYYYGPPHMPPPTRGRGRGGRGGYGYP--PDYYGYEDYYDYY-GYDYHNYRGGYEDPYY 451
Y YG +G GG GGY Y +YYGY DY + GY + RGG+++ Y
Sbjct: 301 GYGNYG-------YNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYK 353
Query: 452 GY 453
Y
Sbjct: 354 PY 355
Score = 58.5 bits (140), Expect = 1e-08
Identities = 67/276 (24%), Positives = 106/276 (38%), Gaps = 76/276 (27%)
Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDH------- 296
++F+G + TK+ + + FSK E + D L P + +RGF F+ +++
Sbjct: 98 KMFIGGLSWDTTKKDLKDYFSKFGE-VVDCTLKLDPITGR-SRGFGFVLFKESESVDKVM 155
Query: 297 --------------------KTAAQVKVLFVRNLANTVTEEILEKAFSQFGKLERVK--- 333
KT VK +FV L+ EE + + F FG++E ++
Sbjct: 156 DQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPM 215
Query: 334 -----KLKDYAFIHFDERDGAVKAMEEM-NGKDLEGENIEIVFAKPPDQKRKERKAQRQA 387
K + + FI F E + K ME+ + L I++ +K Q++++ ++
Sbjct: 216 DNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGF 275
Query: 388 AK-------------NQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDY 434
A NQ Y +Y+ G G YGY YG Y
Sbjct: 276 AGRARGRGGGPSQNWNQGYSNYW---------------NQGYGNYGYNSQGYG-----GY 315
Query: 435 YGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARG 470
GYDY Y YYGY D+ G G RG
Sbjct: 316 GGYDYTGYNN-----YYGYGDYSNQQSGYGKVSRRG 346
>gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo
sapiens]
Length = 484
Score = 73.2 bits (178), Expect = 6e-13
Identities = 42/153 (27%), Positives = 81/153 (52%), Gaps = 19/153 (12%)
Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
++F+G+IPR+L E +L PLFE+ G I++L ++ D TG+++G AF+T+C +E+A +A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 223 YNNHEIRSGKHIGVCISVANN----------------RLFVGSIPKSKTKEQILEEFSKV 266
+ + G + + + A++ +LFVG + K ++++ + F +
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLF-EA 173
Query: 267 TEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299
+ + + PD K G F++Y H A
Sbjct: 174 FGNIEECTILRGPDGNSK--GCAFVKYSSHAEA 204
Score = 39.3 bits (90), Expect = 0.009
Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 6/100 (6%)
Query: 148 PPDSVYSG-----QQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLN 202
P DS G +QP ++FVG + + ED++ LFE G I + ++ P G +
Sbjct: 132 PADSESRGGSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNS 190
Query: 203 RGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVAN 242
+G AFV + + AQ A+ + + G + + A+
Sbjct: 191 KGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFAD 230
Score = 35.8 bits (81), Expect = 0.099
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 10/84 (11%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LF+ + + E+ L+ F +FGK+ + LKD AF+ + ER+ A+KA +
Sbjct: 56 LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
Query: 357 N-GKDLEGENIEIVFAKPPDQKRK 379
+ K L G N I KP D + +
Sbjct: 116 HEQKTLPGMNRPIQ-VKPADSESR 138
Score = 32.3 bits (72), Expect = 1.1
Identities = 14/54 (25%), Positives = 27/54 (50%)
Query: 325 QFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKR 378
+FG E ++ + F+ FD A A++ MNG + + +++ +P D R
Sbjct: 429 EFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANR 482
>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
sapiens]
Length = 485
Score = 72.8 bits (177), Expect = 7e-13
Identities = 42/154 (27%), Positives = 81/154 (52%), Gaps = 20/154 (12%)
Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
++F+G+IPR+L E +L PLFE+ G I++L ++ D TG+++G AF+T+C +E+A +A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 223 YNNHEIRSGKHIGVCISVANN-----------------RLFVGSIPKSKTKEQILEEFSK 265
+ + G + + + A++ +LFVG + K ++++ + F +
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLF-E 173
Query: 266 VTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299
+ + + PD K G F++Y H A
Sbjct: 174 AFGNIEECTILRGPDGNSK--GCAFVKYSSHAEA 205
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 156 QQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEA 215
Q PS ++FVG + + ED++ LFE G I + ++ P G ++G AFV + +
Sbjct: 146 QPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAE 204
Query: 216 AQEAVKLYNNHEIRSGKHIGVCISVAN 242
AQ A+ + + G + + A+
Sbjct: 205 AQAAINALHGSQTMPGASSSLVVKFAD 231
Score = 35.8 bits (81), Expect = 0.099
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 10/84 (11%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LF+ + + E+ L+ F +FGK+ + LKD AF+ + ER+ A+KA +
Sbjct: 56 LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
Query: 357 N-GKDLEGENIEIVFAKPPDQKRK 379
+ K L G N I KP D + +
Sbjct: 116 HEQKTLPGMNRPIQ-VKPADSESR 138
Score = 32.3 bits (72), Expect = 1.1
Identities = 14/54 (25%), Positives = 27/54 (50%)
Query: 325 QFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKR 378
+FG E ++ + F+ FD A A++ MNG + + +++ +P D R
Sbjct: 430 EFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANR 483
>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
sapiens]
Length = 486
Score = 72.8 bits (177), Expect = 7e-13
Identities = 42/154 (27%), Positives = 81/154 (52%), Gaps = 20/154 (12%)
Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
++F+G+IPR+L E +L PLFE+ G I++L ++ D TG+++G AF+T+C +E+A +A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 223 YNNHEIRSGKHIGVCISVANN-----------------RLFVGSIPKSKTKEQILEEFSK 265
+ + G + + + A++ +LFVG + K ++++ + F +
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLF-E 173
Query: 266 VTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299
+ + + PD K G F++Y H A
Sbjct: 174 AFGNIEECTILRGPDGNSK--GCAFVKYSSHAEA 205
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 156 QQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEA 215
Q PS ++FVG + + ED++ LFE G I + ++ P G ++G AFV + +
Sbjct: 146 QPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAE 204
Query: 216 AQEAVKLYNNHEIRSGKHIGVCISVAN 242
AQ A+ + + G + + A+
Sbjct: 205 AQAAINALHGSQTMPGASSSLVVKFAD 231
Score = 35.8 bits (81), Expect = 0.099
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 10/84 (11%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LF+ + + E+ L+ F +FGK+ + LKD AF+ + ER+ A+KA +
Sbjct: 56 LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
Query: 357 N-GKDLEGENIEIVFAKPPDQKRK 379
+ K L G N I KP D + +
Sbjct: 116 HEQKTLPGMNRPIQ-VKPADSESR 138
Score = 32.3 bits (72), Expect = 1.1
Identities = 14/54 (25%), Positives = 27/54 (50%)
Query: 325 QFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKR 378
+FG E ++ + F+ FD A A++ MNG + + +++ +P D R
Sbjct: 431 EFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANR 484
>gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens]
Length = 481
Score = 72.4 bits (176), Expect = 1e-12
Identities = 52/187 (27%), Positives = 89/187 (47%), Gaps = 23/187 (12%)
Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
++FVG+IPR L E +L PLFE+ G I++L ++ D LTGL++G AF+T+C +++A +A
Sbjct: 47 KLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSA 106
Query: 223 YNNHEIRSGKHIGVCISVA-------NNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
+ + G + + + A + +LFVG + K + +E + F + + +
Sbjct: 107 LHEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGH-IEECTV 165
Query: 276 YHQPDDKKKNRGFCFLEY-------------EDHKTAAQVKVLFVRNLANTVTEEILEKA 322
PD K G F+++ +T A V LA+T E L +
Sbjct: 166 LRSPDGTSK--GCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRM 223
Query: 323 FSQFGKL 329
G L
Sbjct: 224 QQMAGHL 230
Score = 38.5 bits (88), Expect = 0.015
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 10/90 (11%)
Query: 149 PDSVYSGQQPSV----------GTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPL 198
P S QQPS G +F+ +P++ + EL+ F G + ++ +D
Sbjct: 373 PVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRA 432
Query: 199 TGLNRGYAFVTFCTKEAAQEAVKLYNNHEI 228
T ++ + FV+F +AQ A++ N +I
Sbjct: 433 TNQSKCFGFVSFDNPTSAQTAIQAMNGFQI 462
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 9/85 (10%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LFV + + E+ L+ F +FG++ + LKD AF+ + RD A+KA +
Sbjct: 48 LFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSAL 107
Query: 357 N-GKDLEGENIEIVFAKPPDQKRKE 380
+ K L G N I + R E
Sbjct: 108 HEQKTLPGMNRPIQVKPAASEGRGE 132
Score = 32.0 bits (71), Expect = 1.4
Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 8/82 (9%)
Query: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356
LF+ +L + L + F FG + K D + F+ FD A A++ M
Sbjct: 398 LFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAM 457
Query: 357 NGKDLEGENIEIVFAKPPDQKR 378
NG + + +++ +P D R
Sbjct: 458 NGFQIGMKRLKVQLKRPKDANR 479
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,660,669
Number of Sequences: 37866
Number of extensions: 1310850
Number of successful extensions: 9886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 319
Number of HSP's successfully gapped in prelim test: 399
Number of HSP's that attempted gapping in prelim test: 5499
Number of HSP's gapped (non-prelim): 3348
length of query: 527
length of database: 18,247,518
effective HSP length: 107
effective length of query: 420
effective length of database: 14,195,856
effective search space: 5962259520
effective search space used: 5962259520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.