Search of human proteins with 22748713

Search of human proteins with 22748713

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748713 ankyrin repeat domain 9 [Homo sapiens]
         (317 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748713 ankyrin repeat domain 9 [Homo sapiens]                    644   0.0  
gi|52486251 phospholipase A2, group VI isoform b [Homo sapiens]        46   5e-05
gi|52486194 phospholipase A2, group VI isoform a [Homo sapiens]        45   6e-05
gi|239746532 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]        43   3e-04
gi|239757533 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]        43   4e-04
gi|239752049 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]        43   4e-04
gi|20270347 ankyrin repeat domain 54 [Homo sapiens]                    42   5e-04
gi|118498337 HECT domain containing 1 [Homo sapiens]                   42   0.001
gi|10863929 ribonuclease L [Homo sapiens]                              41   0.001
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    41   0.002
gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2...    40   0.002
gi|215598819 ankyrin repeat and SOCS box-containing 10 isoform 1...    40   0.002
gi|215598806 ankyrin repeat and SOCS box-containing 10 isoform 3...    40   0.002
gi|168229256 ankyrin repeat domain 41 [Homo sapiens]                   39   0.005
gi|116875852 HECT domain and ankyrin repeat containing, E3 ubiqu...    39   0.006
gi|223634006 hypothetical protein LOC441869 [Homo sapiens]             39   0.008
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]                        37   0.018
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]                         37   0.018
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         37   0.018
gi|24586688 ankyrin repeat and SOCS box-containing protein 16 [H...    37   0.018
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         37   0.023
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    37   0.023
gi|157743292 ankyrin repeat and SOCS box-containing 18 [Homo sap...    37   0.030
gi|155969701 espin-like [Homo sapiens]                                 37   0.030
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         36   0.051
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         36   0.051
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         36   0.051
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         36   0.051
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         36   0.051
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         36   0.051

>gi|22748713 ankyrin repeat domain 9 [Homo sapiens]
          Length = 317

 Score =  644 bits (1662), Expect = 0.0
 Identities = 317/317 (100%), Positives = 317/317 (100%)

Query: 1   MPWDARRPGGGADGGPEASGAARSRAQKQCRKSSFAFYQAVRDLLPVWLLEDMRASEAFH 60
           MPWDARRPGGGADGGPEASGAARSRAQKQCRKSSFAFYQAVRDLLPVWLLEDMRASEAFH
Sbjct: 1   MPWDARRPGGGADGGPEASGAARSRAQKQCRKSSFAFYQAVRDLLPVWLLEDMRASEAFH 60

Query: 61  WDERGRAAAYSPSEALLYALVHDHQAYAHYLLATFPRRALAPPSAGFRCCAAPGPHVALA 120
           WDERGRAAAYSPSEALLYALVHDHQAYAHYLLATFPRRALAPPSAGFRCCAAPGPHVALA
Sbjct: 61  WDERGRAAAYSPSEALLYALVHDHQAYAHYLLATFPRRALAPPSAGFRCCAAPGPHVALA 120

Query: 121 VRYNRVGILRRILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLG 180
           VRYNRVGILRRILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLG
Sbjct: 121 VRYNRVGILRRILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLG 180

Query: 181 HGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTP 240
           HGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTP
Sbjct: 181 HGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTP 240

Query: 241 VGAAGSARQELLGDRPRWQRLLGEDKFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALD 300
           VGAAGSARQELLGDRPRWQRLLGEDKFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALD
Sbjct: 241 VGAAGSARQELLGDRPRWQRLLGEDKFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALD 300

Query: 301 ELPLPPFLQPLDLTGKG 317
           ELPLPPFLQPLDLTGKG
Sbjct: 301 ELPLPPFLQPLDLTGKG 317


>gi|52486251 phospholipase A2, group VI isoform b [Homo sapiens]
          Length = 752

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 51/178 (28%), Positives = 68/178 (38%), Gaps = 38/178 (21%)

Query: 143 ERARVLDRRGC---SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL 199
           E AR+L +RGC   S    G T+LHVA    R +C  +LL HGA+   R   G TPL L 
Sbjct: 298 EMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLA 357

Query: 200 LRQ-----------------LGRDAGATP-----------------SAAGAPASAPGEPR 225
           + +                    D G TP                 S A  PA   G  R
Sbjct: 358 MSKDNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRQLQDLMHISRARKPAFILGSMR 417

Query: 226 QRRLLLLDLLALYTPVGAAGSARQELLGDRPRWQRLLGEDKFQWLAGLAPPSLFARAM 283
             +     LL L    G  G    +LL    +   +  +D F W+AG +   + A A+
Sbjct: 418 DEKRTHDHLLCL-DGGGVKGLIIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAI 474


>gi|52486194 phospholipase A2, group VI isoform a [Homo sapiens]
          Length = 806

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 27/61 (44%), Positives = 34/61 (55%), Gaps = 3/61 (4%)

Query: 143 ERARVLDRRGC---SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL 199
           E AR+L +RGC   S    G T+LHVA    R +C  +LL HGA+   R   G TPL L 
Sbjct: 298 EMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLA 357

Query: 200 L 200
           +
Sbjct: 358 M 358


>gi|239746532 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]
          Length = 345

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 23/48 (47%), Positives = 28/48 (58%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           SR   G T LHVA  + R +C+ LLL HGAS   RD  G TP+ +  R
Sbjct: 248 SRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHR 295


>gi|239757533 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]
          Length = 337

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 22/45 (48%), Positives = 27/45 (60%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLEL 198
           SR   G T LHVA  + R +C+ LLL HGAS   RD  G TP+ +
Sbjct: 240 SRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISI 284


>gi|239752049 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]
          Length = 337

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 22/45 (48%), Positives = 27/45 (60%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLEL 198
           SR   G T LHVA  + R +C+ LLL HGAS   RD  G TP+ +
Sbjct: 240 SRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISI 284


>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
          Length = 300

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 2/105 (1%)

Query: 96  PRRALAPPSAGFRCCAAPGPHVALAVRYNRVGILRRILRTLRDFPAEERARVLDRRG--C 153
           PR  L       R   A  PH  L      V  L+R+  +      E   ++L+     C
Sbjct: 78  PRDELRCKIPAGRLRRAARPHRRLGPTGKEVHALKRLRDSANANDVETVQQLLEDGADPC 137

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLEL 198
           +  + G T+LH A      + + LLL HGA P  RDG G TPL L
Sbjct: 138 AADDKGRTALHFASCNGNDQIVQLLLDHGADPNQRDGLGNTPLHL 182


>gi|118498337 HECT domain containing 1 [Homo sapiens]
          Length = 2610

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 25/60 (41%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 139 FPAEERARVLDRRGCSRVEGG-GTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLE 197
           F  +E    L  RG     G   +SLH A    RP+    LL HGA+P LRD  G TPL+
Sbjct: 406 FGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRHGANPDLRDEDGKTPLD 465


>gi|10863929 ribonuclease L [Homo sapiens]
          Length = 741

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 21/42 (50%), Positives = 26/42 (61%)

Query: 157 EGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLEL 198
           EGG T LH A +++R + + LLL HGA P LR   G TP  L
Sbjct: 57  EGGWTPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFIL 98


>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
           polymerase 2 [Homo sapiens]
          Length = 1166

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 24/61 (39%), Positives = 33/61 (54%), Gaps = 3/61 (4%)

Query: 161 TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGAPASA 220
           T LH A +  R +   LLL HGA P L++  G TPL+L+      D  A  +AA  P++ 
Sbjct: 747 TPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD---DVSALLTAAMPPSAL 803

Query: 221 P 221
           P
Sbjct: 804 P 804



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 20/43 (46%), Positives = 23/43 (53%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL 196
           +R +GG   LH AC     E + LLL HGA P  RD    TPL
Sbjct: 86  ARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPL 128



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 20/100 (20%)

Query: 120 AVRYNRVGILRRILRTLRDFPAEERARVLD-RRGCSR---------VEGGG--------- 160
           A  YNRV ++  +L+   D  A+++  ++     CS          V+ G          
Sbjct: 533 AAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWK 592

Query: 161 -TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL 199
            T LH A    + E   LLL HGA P  ++  G TPL+L+
Sbjct: 593 FTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV 632



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 3/92 (3%)

Query: 108 RCCAAPGPHVALAVRYNRVGILRRILRTLRDFPAEERARVLDRRGCSRVEGGG---TSLH 164
           R CA  G   A A         R +    R+   E   R++     +  +  G   T LH
Sbjct: 4   RRCAGGGAACASAAAEAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLH 63

Query: 165 VACELARPECLFLLLGHGASPGLRDGGGLTPL 196
            A    R + +  LL +GA+   RD GGL PL
Sbjct: 64  FAAGFGRKDVVEYLLQNGANVQARDDGGLIPL 95



 Score = 32.3 bits (72), Expect = 0.57
 Identities = 48/172 (27%), Positives = 59/172 (34%), Gaps = 21/172 (12%)

Query: 149 DRRGCSRVEGG-GTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLE---------- 197
           D   C   +G   T LH+A      E    LL HGA    +D GGL PL           
Sbjct: 668 DNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDV 727

Query: 198 -LLLRQLGRDAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTPVGAAGSARQELLGDRP 256
             LL +      AT   A  P     +  + +L  L LLA       A    +   G  P
Sbjct: 728 AALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL-LLA-----HGADPTLKNQEGQTP 781

Query: 257 RWQRLLGEDKFQWLAGLAPPSLFARAM--QVLVTAISPGRFPEALDELPLPP 306
               +  +D    L    PPS        QVL    SPG   +AL   P  P
Sbjct: 782 -LDLVSADDVSALLTAAMPPSALPSCYKPQVLNGVRSPGATADALSSGPSSP 832



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 1/45 (2%)

Query: 153 CSRVEGG-GTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL 196
           C  +EG   T LH A    R   +  LL HGA    +D GGL PL
Sbjct: 519 CRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPL 563



 Score = 31.6 bits (70), Expect = 0.97
 Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 13/78 (16%)

Query: 119 LAVRYNRVGILRRILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLL 178
           LA  YNRV I++ +L+   D  A+++             G    LH AC     E   LL
Sbjct: 217 LAAGYNRVKIVQLLLQHGADVHAKDK-------------GDLVPLHNACSYGHYEVTELL 263

Query: 179 LGHGASPGLRDGGGLTPL 196
           + HGA     D    TPL
Sbjct: 264 VKHGACVNAMDLWQFTPL 281



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 16/36 (44%), Positives = 20/36 (55%)

Query: 161 TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL 196
           T LH+A    R + + LLL HGA    +D G L PL
Sbjct: 213 TPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPL 248



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 161 TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLEL 198
           T LH A    + +   +LL HGA P +R+  G T L+L
Sbjct: 126 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDL 163


>gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2
           [Homo sapiens]
          Length = 474

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/156 (27%), Positives = 59/156 (37%), Gaps = 22/156 (14%)

Query: 158 GGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL------------ELLLRQLGR 205
           GG T+LH AC      C+ +LL  GA P + D  G  PL            ELLLR   R
Sbjct: 192 GGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGAR 251

Query: 206 DAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTPVGAAGSARQELLGDRPRWQRLLGED 265
             G +      P          RL  ++L  L    GA   AR     +   W  LL   
Sbjct: 252 VDGRSEEEEETPLHVAA-----RLGHVELADLLLRRGACPDAR-----NAEGWTPLLAAC 301

Query: 266 KFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALDE 301
             +  +     +  AR +Q+    +S G   +A D+
Sbjct: 302 DVRCQSITDAEATTARCLQLCSLLLSAGADADAADQ 337



 Score = 32.3 bits (72), Expect = 0.57
 Identities = 37/146 (25%), Positives = 48/146 (32%), Gaps = 27/146 (18%)

Query: 163 LHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGAPASAPG 222
           LH+AC       + LLL  G S    D GG TPL   L+             G  A+   
Sbjct: 343 LHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQ-------------GPAAALAQ 389

Query: 223 EPRQRRLLLLDLLALYTPVGAAGSARQELLGDRPRWQRLLGEDKFQWLAGLAPPSLFARA 282
            P      LL+  A+    GA     Q                     A +  P      
Sbjct: 390 SPEHVVRALLNHGAVRVWPGALPKKHQRFYS--------------SLFALVRQPRSLQHL 435

Query: 283 MQVLVTAISPGRFPEALDELPLPPFL 308
            +  + +   G  P+AL  LPLPP L
Sbjct: 436 SRCALRSHLEGSLPQALPRLPLPPRL 461


>gi|215598819 ankyrin repeat and SOCS box-containing 10 isoform 1
           [Homo sapiens]
          Length = 512

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/156 (27%), Positives = 59/156 (37%), Gaps = 22/156 (14%)

Query: 158 GGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL------------ELLLRQLGR 205
           GG T+LH AC      C+ +LL  GA P + D  G  PL            ELLLR   R
Sbjct: 192 GGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGAR 251

Query: 206 DAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTPVGAAGSARQELLGDRPRWQRLLGED 265
             G +      P          RL  ++L  L    GA   AR     +   W  LL   
Sbjct: 252 VDGRSEEEEETPLHVAA-----RLGHVELADLLLRRGACPDAR-----NAEGWTPLLAAC 301

Query: 266 KFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALDE 301
             +  +     +  AR +Q+    +S G   +A D+
Sbjct: 302 DVRCQSITDAEATTARCLQLCSLLLSAGADADAADQ 337



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 43/164 (26%), Positives = 56/164 (34%), Gaps = 25/164 (15%)

Query: 163 LHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAA-------G 215
           LH+AC       + LLL  G S    D GG TPL   L+        +P          G
Sbjct: 343 LHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRALLNHG 402

Query: 216 APASAPGE-----------PRQRRLLLLDLLALYTPVGAAGSARQELLGDRPRWQRLLGE 264
           A    PG            PR   +L+     +  P  A G    E L    R+   L  
Sbjct: 403 AVRVWPGALPKVLERWSTCPRTIEVLMNTYSVVQLPEEAVGLVTPETLQKHQRFYSSL-- 460

Query: 265 DKFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALDELPLPPFL 308
                 A +  P       +  + +   G  P+AL  LPLPP L
Sbjct: 461 -----FALVRQPRSLQHLSRCALRSHLEGSLPQALPRLPLPPRL 499


>gi|215598806 ankyrin repeat and SOCS box-containing 10 isoform 3
           [Homo sapiens]
          Length = 452

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/156 (27%), Positives = 59/156 (37%), Gaps = 22/156 (14%)

Query: 158 GGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL------------ELLLRQLGR 205
           GG T+LH AC      C+ +LL  GA P + D  G  PL            ELLLR   R
Sbjct: 132 GGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGAR 191

Query: 206 DAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTPVGAAGSARQELLGDRPRWQRLLGED 265
             G +      P          RL  ++L  L    GA   AR     +   W  LL   
Sbjct: 192 VDGRSEEEEETPLHVAA-----RLGHVELADLLLRRGACPDAR-----NAEGWTPLLAAC 241

Query: 266 KFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALDE 301
             +  +     +  AR +Q+    +S G   +A D+
Sbjct: 242 DVRCQSITDAEATTARCLQLCSLLLSAGADADAADQ 277



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 43/164 (26%), Positives = 56/164 (34%), Gaps = 25/164 (15%)

Query: 163 LHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAA-------G 215
           LH+AC       + LLL  G S    D GG TPL   L+        +P          G
Sbjct: 283 LHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRALLNHG 342

Query: 216 APASAPGE-----------PRQRRLLLLDLLALYTPVGAAGSARQELLGDRPRWQRLLGE 264
           A    PG            PR   +L+     +  P  A G    E L    R+   L  
Sbjct: 343 AVRVWPGALPKVLERWSTCPRTIEVLMNTYSVVQLPEEAVGLVTPETLQKHQRFYSSL-- 400

Query: 265 DKFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALDELPLPPFL 308
                 A +  P       +  + +   G  P+AL  LPLPP L
Sbjct: 401 -----FALVRQPRSLQHLSRCALRSHLEGSLPQALPRLPLPPRL 439


>gi|168229256 ankyrin repeat domain 41 [Homo sapiens]
          Length = 615

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 22/42 (52%), Positives = 24/42 (57%)

Query: 161 TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           T LHVA        L LLL  GA P LRD  GL PL+L L+Q
Sbjct: 78  TPLHVAAAWGCRRGLELLLSQGADPALRDQDGLRPLDLALQQ 119



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 9/77 (11%)

Query: 131 RILRTLRDFPAEERARVLD---RRGCSR---VEGGGTSLHVACELARPE---CLFLLLGH 181
           R+ R LRD   EE    ++   R G      +E G  ++H+A     P    CL  LL  
Sbjct: 6   RLARRLRDALREEEPWAVEELLRCGADPNLVLEDGAAAVHLAAGARHPRGLRCLGALLRQ 65

Query: 182 GASPGLRDGGGLTPLEL 198
           G  P  R    LTPL +
Sbjct: 66  GGDPNARSVEALTPLHV 82


>gi|116875852 HECT domain and ankyrin repeat containing, E3
           ubiquitin protein ligase 1 [Homo sapiens]
          Length = 909

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 19/39 (48%), Positives = 22/39 (56%)

Query: 163 LHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           LH+A      ECL LLL  GA+P  +D  G TPL L  R
Sbjct: 69  LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAAR 107


>gi|223634006 hypothetical protein LOC441869 [Homo sapiens]
          Length = 399

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 19/43 (44%), Positives = 27/43 (62%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL 196
           +R   G T+L +A  L R + + +LLGHGA PG+RD  G + L
Sbjct: 231 ARDGAGATALGLAAALGRSQDIEVLLGHGADPGIRDRHGRSAL 273



 Score = 35.4 bits (80), Expect = 0.067
 Identities = 36/100 (36%), Positives = 42/100 (42%), Gaps = 17/100 (17%)

Query: 159 GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLE--------LLLRQLGRDAGAT 210
           G T+LH A          LLL  GAS   R G GLTPL         LL  +L    G  
Sbjct: 107 GRTALHEAAWHGHSRVAELLLQRGASAAARSGTGLTPLHWAAALGHTLLAARLLEAPGPG 166

Query: 211 PSAAGAP-----ASAPGEPRQRRLLLLDLLALYTPVGAAG 245
           P+AA A       +A       RL +L+LLA     G AG
Sbjct: 167 PAAAEAEDARGWTAAHWAAAGGRLAVLELLA----AGGAG 202


>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
          Length = 1863

 Score = 37.4 bits (85), Expect = 0.018
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 143 ERARVLDRRGC---SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL 199
           E  R L R G    +R     T LH+A  L + E + LLL H A P      G TPL + 
Sbjct: 457 EVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS 516

Query: 200 LRQLGRDAGATPSAAGAPAS 219
            R+   D  +    AGA  S
Sbjct: 517 AREGQVDVASVLLEAGAAHS 536



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 9/68 (13%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDG 190
           R+ + L D  A   AR L+         G T LH+AC+  R + + LL+ +GAS      
Sbjct: 358 RVTKLLLDKRANPNARALN---------GFTPLHIACKKNRIKVMELLVKYGASIQAITE 408

Query: 191 GGLTPLEL 198
            GLTP+ +
Sbjct: 409 SGLTPIHV 416



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 2/58 (3%)

Query: 147 VLDRRGCSRVEG--GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           +L RR  +   G  G T LHVA      +   LLL  GASP      G TPL +  ++
Sbjct: 561 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK 618



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 17/45 (37%), Positives = 24/45 (53%)

Query: 157 EGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           E G T +HVA  +     + LLL +GASP + +  G T L +  R
Sbjct: 408 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAAR 452



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 138 DFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLE 197
           D  A+ +++++  R     E G T LH+A          LLL  GA+       G+TPL 
Sbjct: 194 DHNADVQSKMMVNR---TTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 250

Query: 198 L 198
           +
Sbjct: 251 V 251



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 15/48 (31%), Positives = 22/48 (45%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           ++ + G T LH A +      + +LL HGA P      G T L +  R
Sbjct: 735 AKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKR 782



 Score = 28.9 bits (63), Expect = 6.3
 Identities = 14/49 (28%), Positives = 26/49 (53%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           S  + G T+LH+A    + E + +L+  GA+   +   G TPL +  ++
Sbjct: 71  SATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQE 119


>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 37.4 bits (85), Expect = 0.018
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 143 ERARVLDRRGC---SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL 199
           E  R L R G    +R     T LH+A  L + E + LLL H A P      G TPL + 
Sbjct: 478 EVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS 537

Query: 200 LRQLGRDAGATPSAAGAPAS 219
            R+   D  +    AGA  S
Sbjct: 538 AREGQVDVASVLLEAGAAHS 557



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 9/68 (13%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDG 190
           R+ + L D  A   AR L+         G T LH+AC+  R + + LL+ +GAS      
Sbjct: 379 RVTKLLLDKRANPNARALN---------GFTPLHIACKKNRIKVMELLVKYGASIQAITE 429

Query: 191 GGLTPLEL 198
            GLTP+ +
Sbjct: 430 SGLTPIHV 437



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 2/58 (3%)

Query: 147 VLDRRGCSRVEG--GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           +L RR  +   G  G T LHVA      +   LLL  GASP      G TPL +  ++
Sbjct: 582 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK 639



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 17/45 (37%), Positives = 24/45 (53%)

Query: 157 EGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           E G T +HVA  +     + LLL +GASP + +  G T L +  R
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAAR 473



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 138 DFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLE 197
           D  A+ +++++  R     E G T LH+A          LLL  GA+       G+TPL 
Sbjct: 215 DHNADVQSKMMVNR---TTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 271

Query: 198 L 198
           +
Sbjct: 272 V 272



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 15/48 (31%), Positives = 22/48 (45%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           ++ + G T LH A +      + +LL HGA P      G T L +  R
Sbjct: 756 AKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKR 803



 Score = 28.9 bits (63), Expect = 6.3
 Identities = 14/49 (28%), Positives = 26/49 (53%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           S  + G T+LH+A    + E + +L+  GA+   +   G TPL +  ++
Sbjct: 92  SATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQE 140


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 37.4 bits (85), Expect = 0.018
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 143 ERARVLDRRGC---SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL 199
           E  R L R G    +R     T LH+A  L + E + LLL H A P      G TPL + 
Sbjct: 478 EVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS 537

Query: 200 LRQLGRDAGATPSAAGAPAS 219
            R+   D  +    AGA  S
Sbjct: 538 AREGQVDVASVLLEAGAAHS 557



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 9/68 (13%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDG 190
           R+ + L D  A   AR L+         G T LH+AC+  R + + LL+ +GAS      
Sbjct: 379 RVTKLLLDKRANPNARALN---------GFTPLHIACKKNRIKVMELLVKYGASIQAITE 429

Query: 191 GGLTPLEL 198
            GLTP+ +
Sbjct: 430 SGLTPIHV 437



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 2/58 (3%)

Query: 147 VLDRRGCSRVEG--GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           +L RR  +   G  G T LHVA      +   LLL  GASP      G TPL +  ++
Sbjct: 582 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK 639



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 17/45 (37%), Positives = 24/45 (53%)

Query: 157 EGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           E G T +HVA  +     + LLL +GASP + +  G T L +  R
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAAR 473



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 138 DFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLE 197
           D  A+ +++++  R     E G T LH+A          LLL  GA+       G+TPL 
Sbjct: 215 DHNADVQSKMMVNR---TTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 271

Query: 198 L 198
           +
Sbjct: 272 V 272



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 15/48 (31%), Positives = 22/48 (45%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           ++ + G T LH A +      + +LL HGA P      G T L +  R
Sbjct: 756 AKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKR 803



 Score = 28.9 bits (63), Expect = 6.3
 Identities = 14/49 (28%), Positives = 26/49 (53%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           S  + G T+LH+A    + E + +L+  GA+   +   G TPL +  ++
Sbjct: 92  SATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQE 140


>gi|24586688 ankyrin repeat and SOCS box-containing protein 16 [Homo
           sapiens]
          Length = 453

 Score = 37.4 bits (85), Expect = 0.018
 Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 12/88 (13%)

Query: 145 ARVLDRRGC---SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL-- 199
           AR L R+G    +RV GG  +LH AC  A+ +C+ LLL  GA   +    G TPL L   
Sbjct: 127 ARHLIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTI 185

Query: 200 -----LRQLGRDAGATPS-AAGAPASAP 221
                  +L  +AGAT + AAG     P
Sbjct: 186 PESLQCAKLLLEAGATVNLAAGESQETP 213



 Score = 31.6 bits (70), Expect = 0.97
 Identities = 29/92 (31%), Positives = 34/92 (36%), Gaps = 15/92 (16%)

Query: 157 EGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGA 216
           E   T LHVA      + + L L HGA  GLR   G T L               + A A
Sbjct: 208 ESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETAL---------------NTACA 252

Query: 217 PASAPGEPRQRRLLLLDLLALYTPVGAAGSAR 248
            A  PG  R+ +     LL       AAG  R
Sbjct: 253 GAEGPGSCRRHQAAARRLLEAGADARAAGRKR 284


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 23/64 (35%), Positives = 29/64 (45%)

Query: 157 EGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGA 216
           + G T LHVA      +   LLL  GASP      G TPL +  ++   D   T    GA
Sbjct: 596 KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGA 655

Query: 217 PASA 220
            A+A
Sbjct: 656 DANA 659



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 9/68 (13%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDG 190
           ++ + L D  A   A+ L+         G T LH+AC+  R + + LLL HGAS      
Sbjct: 381 KVAKVLLDKKANPNAKALN---------GFTPLHIACKKNRIKVMELLLKHGASIQAVTE 431

Query: 191 GGLTPLEL 198
            GLTP+ +
Sbjct: 432 SGLTPIHV 439



 Score = 35.4 bits (80), Expect = 0.067
 Identities = 26/70 (37%), Positives = 31/70 (44%), Gaps = 7/70 (10%)

Query: 159 GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL-------LRQLGRDAGATP 211
           G T LHVA +  + E   LLL   ASP      GLTPL +        +  L  D GA+P
Sbjct: 565 GFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASP 624

Query: 212 SAAGAPASAP 221
            AA      P
Sbjct: 625 HAAAKNGYTP 634



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 21/59 (35%), Positives = 27/59 (45%)

Query: 161 TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGAPAS 219
           T LH++  L + + +  LL  GASP      G TPL L  R+   D  A     GA  S
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 559



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 14/93 (15%)

Query: 115 PHVALAVRYNRVGILRR-----ILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACEL 169
           PH A    Y  + I  +     I  TL ++ A+  A  + R+G +       S+H+A + 
Sbjct: 624 PHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD--ANAVTRQGIA-------SVHLAAQE 674

Query: 170 ARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
              + + LLLG  A+  L +  GLTPL L  ++
Sbjct: 675 GHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQE 707



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 21/112 (18%)

Query: 159 GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL-------ELLLRQLGRDAGATP 211
           G T LH++      +    LL HGAS  +    G TPL       +L +  L     A+P
Sbjct: 532 GYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASP 591

Query: 212 SAAGAPASAP------GEPRQRRLLLLDLLAL--------YTPVGAAGSARQ 249
            AAG     P       + ++  LLLLD  A         YTP+  A    Q
Sbjct: 592 DAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 643



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 17/46 (36%), Positives = 25/46 (54%)

Query: 157 EGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           + G T L++A +    E +  LL +GAS  L    G TPL + L+Q
Sbjct: 138 QNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQ 183



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 16/45 (35%), Positives = 22/45 (48%)

Query: 157 EGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           E G T +HVA  +     +  L+ HGASP   +  G T L +  R
Sbjct: 431 ESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAAR 475



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 145 ARVLDRRGC---SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLR 201
           A VL  +G    ++ + G T LHV C     + +  LL H A    +   G TPL    +
Sbjct: 713 AEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQ 772

Query: 202 Q 202
           Q
Sbjct: 773 Q 773



 Score = 28.9 bits (63), Expect = 6.3
 Identities = 13/44 (29%), Positives = 25/44 (56%)

Query: 159 GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQ 202
           G T+LH+A    + E + +L+ +GA+   +   G TPL +  ++
Sbjct: 107 GNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQE 150


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
           polymerase [Homo sapiens]
          Length = 1327

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 19/43 (44%), Positives = 22/43 (51%)

Query: 154 SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL 196
           +R +GG   LH AC     E + LLL  GA P  RD    TPL
Sbjct: 244 ARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPL 286



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 17/38 (44%), Positives = 23/38 (60%)

Query: 161 TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLEL 198
           T LH A +  R +   LLL HGA P +++  G TPL+L
Sbjct: 905 TPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 942



 Score = 35.4 bits (80), Expect = 0.067
 Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 13/78 (16%)

Query: 119 LAVRYNRVGILRRILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLL 178
           LA  YNRV I++ +L+   D  A+++             GG   LH AC     E   LL
Sbjct: 375 LAAGYNRVRIVQLLLQHGADVHAKDK-------------GGLVPLHNACSYGHYEVTELL 421

Query: 179 LGHGASPGLRDGGGLTPL 196
           L HGA     D    TPL
Sbjct: 422 LKHGACVNAMDLWQFTPL 439



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 13/107 (12%)

Query: 99  ALAPPSAGFRCCAAPGPHVA------LAVRYNRVGILRRILRTLRDFPAEERARVLDRRG 152
           A +P +AG    A  GP  A       AV     G LR +L   R+       R++D   
Sbjct: 151 AESPEAAGVSSTAPLGPGAAGPGTGVPAVS----GALRELLEACRNGDVSRVKRLVDAAN 206

Query: 153 CSRVEGGG---TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL 196
            +  +  G   + LH A    R + +  LL  GA+   RD GGL PL
Sbjct: 207 VNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPL 253



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 23/119 (19%)

Query: 104 SAGFRCCAAPGPH---VALAVRYNRVGILRRILRTLRDFPAEER---------------- 144
           S    C    G H   +  A  YNRV ++  +L    D  A+++                
Sbjct: 672 SQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYE 731

Query: 145 -ARVLDRRGCSRVEGG---GTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELL 199
            A +L R G S         T LH A    + E   LLL HGA P  ++  G TPL+L+
Sbjct: 732 VAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV 790



 Score = 32.3 bits (72), Expect = 0.57
 Identities = 17/36 (47%), Positives = 20/36 (55%)

Query: 161 TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL 196
           T LH+A    R   + LLL HGA    +D GGL PL
Sbjct: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPL 406



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 1/45 (2%)

Query: 153 CSRVEG-GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPL 196
           C   +G   T LH+A      E    LL HGA    +D GGL PL
Sbjct: 830 CRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPL 874



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 20/88 (22%)

Query: 161 TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGAPASA 220
           T LH A    + +   +LL HGA P +R+  G + L+L          A PS   A A  
Sbjct: 284 TPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDL----------ADPS---AKAVL 330

Query: 221 PGEPRQRRLLLL-------DLLALYTPV 241
            GE ++  LL          L+AL TP+
Sbjct: 331 TGEYKKDELLEAARSGNEEKLMALLTPL 358


>gi|157743292 ankyrin repeat and SOCS box-containing 18 [Homo
           sapiens]
          Length = 466

 Score = 36.6 bits (83), Expect = 0.030
 Identities = 50/178 (28%), Positives = 68/178 (38%), Gaps = 15/178 (8%)

Query: 147 VLDRRGC---SRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQL 203
           +L RRG    +R E   + LH AC  A      LLL HGA  G  D GG +PL  +L+  
Sbjct: 278 LLLRRGAEADARDEDERSPLHKACGHASHSLARLLLRHGADAGALDYGGASPLGRVLQTA 337

Query: 204 GRDAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTPVGAA-----GSARQELLGDRPRW 258
                A+P          G P         +L     V A       S  Q  L +   W
Sbjct: 338 SCALQASPQRTVQALLNHGSPTVWPDAFPKVLKTCASVPAVIEVLFNSYPQLCLSE--SW 395

Query: 259 QRLLGEDKFQ----WLAGLAPPSLFARAMQVLVTAISPGRF-PEALDELPLPPFLQPL 311
           + ++ E+ FQ    +   L   +L  R +Q L        F     D +PL P  +PL
Sbjct: 396 KEVIPEEVFQMHKPFYQSLFALALTPRCLQHLCRCALRRLFGKRCFDLIPLLPLPKPL 453



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 19/41 (46%), Positives = 21/41 (51%)

Query: 158 GGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLEL 198
           GG  +LH AC      C+ LLL H A P L    GL PL L
Sbjct: 151 GGRGALHEACLGGHTACVRLLLQHRADPDLLSAEGLAPLHL 191



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 39/110 (35%), Positives = 43/110 (39%), Gaps = 23/110 (20%)

Query: 145 ARVLDRRGCS--RVEGGG--TSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLL 200
           A+ L   G S  RV G G  T LHVA +    E   L LG GA    R+G G T L    
Sbjct: 201 AQALLEHGASVQRVGGTGRDTPLHVAAQRGLDEHARLYLGRGAHVDARNGRGETAL---- 256

Query: 201 RQLGRDAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTPVGAAGSARQE 250
                      SAA   A  P E  +     L L AL    GA   AR E
Sbjct: 257 -----------SAACGAARRPDEHGR----CLRLCALLLRRGAEADARDE 291


>gi|155969701 espin-like [Homo sapiens]
          Length = 1005

 Score = 36.6 bits (83), Expect = 0.030
 Identities = 18/40 (45%), Positives = 21/40 (52%)

Query: 159 GGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLEL 198
           GGT LH A E  + EC   L+ H   P LRD  G T  +L
Sbjct: 271 GGTPLHDAAENGQMECCQTLVSHHVDPSLRDEDGYTAADL 310


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEG---GGTSLHVACELARPECLFLLLGHGASPGL 187
           R+L+ + +  AE+ A +L ++G S  +    G T+ H+A      ECL +++ HG     
Sbjct: 25  RLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTA 84

Query: 188 RDGGGLTPLEL 198
           +D  G + L L
Sbjct: 85  QDTTGHSALHL 95


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEG---GGTSLHVACELARPECLFLLLGHGASPGL 187
           R+L+ + +  AE+ A +L ++G S  +    G T+ H+A      ECL +++ HG     
Sbjct: 14  RLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTA 73

Query: 188 RDGGGLTPLEL 198
           +D  G + L L
Sbjct: 74  QDTTGHSALHL 84


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEG---GGTSLHVACELARPECLFLLLGHGASPGL 187
           R+L+ + +  AE+ A +L ++G S  +    G T+ H+A      ECL +++ HG     
Sbjct: 22  RLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTA 81

Query: 188 RDGGGLTPLEL 198
           +D  G + L L
Sbjct: 82  QDTTGHSALHL 92


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEG---GGTSLHVACELARPECLFLLLGHGASPGL 187
           R+L+ + +  AE+ A +L ++G S  +    G T+ H+A      ECL +++ HG     
Sbjct: 22  RLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTA 81

Query: 188 RDGGGLTPLEL 198
           +D  G + L L
Sbjct: 82  QDTTGHSALHL 92


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEG---GGTSLHVACELARPECLFLLLGHGASPGL 187
           R+L+ + +  AE+ A +L ++G S  +    G T+ H+A      ECL +++ HG     
Sbjct: 22  RLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTA 81

Query: 188 RDGGGLTPLEL 198
           +D  G + L L
Sbjct: 82  QDTTGHSALHL 92


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 131 RILRTLRDFPAEERARVLDRRGCSRVEG---GGTSLHVACELARPECLFLLLGHGASPGL 187
           R+L+ + +  AE+ A +L ++G S  +    G T+ H+A      ECL +++ HG     
Sbjct: 22  RLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTA 81

Query: 188 RDGGGLTPLEL 198
           +D  G + L L
Sbjct: 82  QDTTGHSALHL 92


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,449,575
Number of Sequences: 37866
Number of extensions: 723875
Number of successful extensions: 3578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 2982
Number of HSP's gapped (non-prelim): 661
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.