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Search of human proteins with 22748695
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22748695 DEP domain containing 4 [Homo sapiens]
(294 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22748695 DEP domain containing 4 [Homo sapiens] 605 e-173
gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens] 144 7e-35
gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens] 144 7e-35
gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens] 62 6e-10
gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens] 62 6e-10
gi|166295188 DEP domain containing 1 isoform a [Homo sapiens] 62 6e-10
gi|38488716 DEP domain containing 1 isoform b [Homo sapiens] 62 6e-10
gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R... 41 0.001
gi|189571664 DEP domain containing 6 [Homo sapiens] 40 0.002
gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isof... 39 0.007
gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isof... 39 0.007
gi|148747862 Rap guanine nucleotide exchange factor 3 isoform b ... 35 0.10
gi|20070215 Rap guanine nucleotide exchange factor 3 isoform b [... 35 0.10
gi|148747859 Rap guanine nucleotide exchange factor 3 isoform a ... 35 0.10
gi|7706643 pleckstrin 2 [Homo sapiens] 32 0.51
gi|47578117 DEP domain containing 2 isoform b [Homo sapiens] 32 0.51
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens] 32 0.51
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 31 1.5
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 31 1.5
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 31 1.5
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre... 30 2.5
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr... 30 2.5
gi|148276990 zinc finger and BTB domain containing 38 [Homo sapi... 30 3.3
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 29 5.7
gi|239757132 PREDICTED: hypothetical protein [Homo sapiens] 28 7.4
gi|239751635 PREDICTED: hypothetical protein XP_002347941 [Homo ... 28 7.4
gi|239746147 PREDICTED: hypothetical protein XP_002344287 [Homo ... 28 7.4
gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Hom... 28 7.4
gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Hom... 28 7.4
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 28 7.4
>gi|22748695 DEP domain containing 4 [Homo sapiens]
Length = 294
Score = 605 bits (1560), Expect = e-173
Identities = 294/294 (100%), Positives = 294/294 (100%)
Query: 1 MVPGEEPARELMAVLLTPRFRRLVSQNELPGPGLNGPSSRNRRDGFCRKRRTGCSGPFQA 60
MVPGEEPARELMAVLLTPRFRRLVSQNELPGPGLNGPSSRNRRDGFCRKRRTGCSGPFQA
Sbjct: 1 MVPGEEPARELMAVLLTPRFRRLVSQNELPGPGLNGPSSRNRRDGFCRKRRTGCSGPFQA 60
Query: 61 TQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKG 120
TQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKG
Sbjct: 61 TQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKG 120
Query: 121 VHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKDAENEF 180
VHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKDAENEF
Sbjct: 121 VHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKDAENEF 180
Query: 181 NETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRLSKEDVWKEQT 240
NETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRLSKEDVWKEQT
Sbjct: 181 NETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRLSKEDVWKEQT 240
Query: 241 LLCLLQLIHLPFLDNILEPPVKTQNLQLNKEEDLVITNTCLDRELIPSLCLPEK 294
LLCLLQLIHLPFLDNILEPPVKTQNLQLNKEEDLVITNTCLDRELIPSLCLPEK
Sbjct: 241 LLCLLQLIHLPFLDNILEPPVKTQNLQLNKEEDLVITNTCLDRELIPSLCLPEK 294
>gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]
Length = 502
Score = 144 bits (364), Expect = 7e-35
Identities = 87/233 (37%), Positives = 133/233 (57%), Gaps = 13/233 (5%)
Query: 57 PFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDIS 116
PF AT +W II++LQ QVE+K+RRH L+ + DCF GS+AVDV+ SHL+QN DI
Sbjct: 23 PFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIP 82
Query: 117 CLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRF--LGNKSSYDCCKRQK 174
K V +CQ LM++KVFE V K+F K+K+ FEDS+ SLYRF + N+ S Q
Sbjct: 83 RAKVVRVCQALMDYKVFEAV-PTKVFGKDKKPTFEDSSCSLYRFTTIPNQDS------QL 135
Query: 175 DAENEFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRLSKED 234
EN+ R + + +I +E+L ++ PA P++ + +
Sbjct: 136 GKENKLYSPARYADALFK---SSDIRSASLEDLWENLSLKPANSPHVNISATLSPQVINE 192
Query: 235 VWKEQTLLCLLQLIHLPFLDNILEPPVKTQNL-QLNKEEDLVITNTCLDRELI 286
VW+E+T+ LLQL+ LP LD++L+ + Q ++ +V ++ LDR ++
Sbjct: 193 VWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGIL 245
>gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]
Length = 511
Score = 144 bits (364), Expect = 7e-35
Identities = 87/233 (37%), Positives = 133/233 (57%), Gaps = 13/233 (5%)
Query: 57 PFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDIS 116
PF AT +W II++LQ QVE+K+RRH L+ + DCF GS+AVDV+ SHL+QN DI
Sbjct: 32 PFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIP 91
Query: 117 CLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRF--LGNKSSYDCCKRQK 174
K V +CQ LM++KVFE V K+F K+K+ FEDS+ SLYRF + N+ S Q
Sbjct: 92 RAKVVRVCQALMDYKVFEAV-PTKVFGKDKKPTFEDSSCSLYRFTTIPNQDS------QL 144
Query: 175 DAENEFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRLSKED 234
EN+ R + + +I +E+L ++ PA P++ + +
Sbjct: 145 GKENKLYSPARYADALFK---SSDIRSASLEDLWENLSLKPANSPHVNISATLSPQVINE 201
Query: 235 VWKEQTLLCLLQLIHLPFLDNILEPPVKTQNL-QLNKEEDLVITNTCLDRELI 286
VW+E+T+ LLQL+ LP LD++L+ + Q ++ +V ++ LDR ++
Sbjct: 202 VWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGIL 254
>gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]
Length = 529
Score = 62.0 bits (149), Expect = 6e-10
Identities = 52/208 (25%), Positives = 101/208 (48%), Gaps = 13/208 (6%)
Query: 56 GPFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDI 115
GP++AT+LW+ + +A++ +++ R ++Y+ CFT ++AVD L L++ + ++
Sbjct: 9 GPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVD-WLHELLRCSQNFGPEV 67
Query: 116 SCLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKR--- 172
+ + V L + + + V E + K E +FED N LYRF + K+
Sbjct: 68 TRKQTVQLLKKFLKNHVIEDIK-----GKWGEEDFED-NRHLYRFPPSSPLKPYPKKPPN 121
Query: 173 QKDAEN--EFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRL 230
QKD E+N+ L PG + P+ + + H+I + ++
Sbjct: 122 QKDVIKFPEWND-LPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA 180
Query: 231 SKEDVWKEQTLLCLLQLIHLPFLDNILE 258
+ E++WK TL L +++ L L+ +L+
Sbjct: 181 NVEEIWKSMTLSYLQKILGLDSLEEVLD 208
>gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens]
Length = 467
Score = 62.0 bits (149), Expect = 6e-10
Identities = 52/208 (25%), Positives = 101/208 (48%), Gaps = 13/208 (6%)
Query: 56 GPFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDI 115
GP++AT+LW+ + +A++ +++ R ++Y+ CFT ++AVD L L++ + ++
Sbjct: 9 GPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVD-WLHELLRCSQNFGPEV 67
Query: 116 SCLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKR--- 172
+ + V L + + + V E + K E +FED N LYRF + K+
Sbjct: 68 TRKQTVQLLKKFLKNHVIEDIK-----GKWGEEDFED-NRHLYRFPPSSPLKPYPKKPPN 121
Query: 173 QKDAEN--EFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRL 230
QKD E+N+ L PG + P+ + + H+I + ++
Sbjct: 122 QKDVIKFPEWND-LPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA 180
Query: 231 SKEDVWKEQTLLCLLQLIHLPFLDNILE 258
+ E++WK TL L +++ L L+ +L+
Sbjct: 181 NVEEIWKSMTLSYLQKILGLDSLEEVLD 208
>gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]
Length = 811
Score = 62.0 bits (149), Expect = 6e-10
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 27/218 (12%)
Query: 56 GPFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDI 115
GP++AT+LW+ + S +A + +++ R H + Y +CFT +AVD L L++N ++
Sbjct: 9 GPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVD-WLYDLLRNNSNFGPEV 67
Query: 116 SCLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLG------------- 162
+ + + L + + + V E + K E D N L+RF
Sbjct: 68 TRQQTIQLLRKFLKNHVIEDI------KGRWGSENVDDNNQLFRFPATSPLKTLPRRYPE 121
Query: 163 -NKSSYDCCKRQKDAENEFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNI 221
K++ + + KD+ + R + L+QE GE+ E+I+ N
Sbjct: 122 LRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ------ENA 175
Query: 222 TVQKPFLRLSKEDVWKEQTLLCLLQLIHLPFLDNILEP 259
+ + E+VW+ L+ L ++ +P L+ ++ P
Sbjct: 176 IDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINP 213
>gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]
Length = 527
Score = 62.0 bits (149), Expect = 6e-10
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 27/218 (12%)
Query: 56 GPFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDI 115
GP++AT+LW+ + S +A + +++ R H + Y +CFT +AVD L L++N ++
Sbjct: 9 GPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVD-WLYDLLRNNSNFGPEV 67
Query: 116 SCLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLG------------- 162
+ + + L + + + V E + K E D N L+RF
Sbjct: 68 TRQQTIQLLRKFLKNHVIEDI------KGRWGSENVDDNNQLFRFPATSPLKTLPRRYPE 121
Query: 163 -NKSSYDCCKRQKDAENEFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNI 221
K++ + + KD+ + R + L+QE GE+ E+I+ N
Sbjct: 122 LRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ------ENA 175
Query: 222 TVQKPFLRLSKEDVWKEQTLLCLLQLIHLPFLDNILEP 259
+ + E+VW+ L+ L ++ +P L+ ++ P
Sbjct: 176 IDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINP 213
>gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac
exchange factor 1 [Homo sapiens]
Length = 1659
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 26/132 (19%)
Query: 68 IHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVL 127
+HSL V IK R +HL+TYK GS VD +L+ Q C + + L GV LC
Sbjct: 521 LHSLYTPV-IKDRDYHLKTYKSVLPGSKLVDWLLA---QGDCQTREEAVAL-GVGLCNNG 575
Query: 128 MNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKDAENEFNETLRPG 187
H V E + EF D + +RF ++ + + + N+ LR
Sbjct: 576 FMHHVLE------------KSEFRDES-QYFRFHADE--------EMEGTSSKNKQLRND 614
Query: 188 YEMISNPLAQEI 199
++++ N LA+ +
Sbjct: 615 FKLVENILAKRL 626
Score = 31.2 bits (69), Expect = 1.1
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 17/99 (17%)
Query: 77 IKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPV 136
IK RR L T CF G++ V + L++ +S + +GV+L Q L+ + + V
Sbjct: 428 IKDRRRKLSTVPKCFLGNEFV----AWLLEIGEISKTE----EGVNLGQALLENGIIHHV 479
Query: 137 GMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKD 175
K FK E+ +YRF + +Y +D
Sbjct: 480 SDKHQFKNEQ---------VMYRFRYDDGTYKARSELED 509
>gi|189571664 DEP domain containing 6 [Homo sapiens]
Length = 409
Score = 40.0 bits (92), Expect = 0.002
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 71 LQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLM---QNTCLSSNDISCLKGV--HLCQ 125
L + IK RRHHL+TY +CF + +D ++ H + T + +G+ H+C
Sbjct: 44 LHEEKVIKDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCD 103
Query: 126 VLMNHKVFEPVGMKKLFKKE 145
HK F+ V + F+K+
Sbjct: 104 ---EHKEFKDVKLFYRFRKD 120
>gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isoform
b [Homo sapiens]
Length = 867
Score = 38.5 bits (88), Expect = 0.007
Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 19/111 (17%)
Query: 77 IKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPV 136
I+ R++HL+TY+ C G++ VD + + Q C+ S + V + QVL+ V V
Sbjct: 78 IRDRKYHLKTYRQCCVGTELVDWM---MQQTPCVHSR----TQAVGMWQVLLEDGVLNHV 130
Query: 137 GMKKLFKKEKELEFEDSNISLYRFLGNK---SSYDCCKRQKDAENEFNETL 184
++E F+D + YRFL ++ + + +K+ + E +T+
Sbjct: 131 --------DQEHHFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEELQDTM 172
>gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isoform
a [Homo sapiens]
Length = 1011
Score = 38.5 bits (88), Expect = 0.007
Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 19/111 (17%)
Query: 77 IKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPV 136
I+ R++HL+TY+ C G++ VD + + Q C+ S + V + QVL+ V V
Sbjct: 222 IRDRKYHLKTYRQCCVGTELVDWM---MQQTPCVHSR----TQAVGMWQVLLEDGVLNHV 274
Query: 137 GMKKLFKKEKELEFEDSNISLYRFLGNK---SSYDCCKRQKDAENEFNETL 184
++E F+D + YRFL ++ + + +K+ + E +T+
Sbjct: 275 --------DQEHHFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEELQDTM 316
>gi|148747862 Rap guanine nucleotide exchange factor 3 isoform b
[Homo sapiens]
Length = 881
Score = 34.7 bits (78), Expect = 0.10
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 77 IKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPV 136
I+ R++HL+ Y+ C +G + VD +L+ L S + V +CQVL++
Sbjct: 74 IRDRKYHLRLYRQCCSGRELVDGILA-------LGLGVHSRSQVVGICQVLLDEGA---- 122
Query: 137 GMKKLFKKEKELEFEDSNISLYRFLG 162
L + + F+D + YRF G
Sbjct: 123 ----LCHVKHDWAFQDRDAQFYRFPG 144
>gi|20070215 Rap guanine nucleotide exchange factor 3 isoform b
[Homo sapiens]
Length = 881
Score = 34.7 bits (78), Expect = 0.10
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 77 IKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPV 136
I+ R++HL+ Y+ C +G + VD +L+ L S + V +CQVL++
Sbjct: 74 IRDRKYHLRLYRQCCSGRELVDGILA-------LGLGVHSRSQVVGICQVLLDEGA---- 122
Query: 137 GMKKLFKKEKELEFEDSNISLYRFLG 162
L + + F+D + YRF G
Sbjct: 123 ----LCHVKHDWAFQDRDAQFYRFPG 144
>gi|148747859 Rap guanine nucleotide exchange factor 3 isoform a
[Homo sapiens]
Length = 923
Score = 34.7 bits (78), Expect = 0.10
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 77 IKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPV 136
I+ R++HL+ Y+ C +G + VD +L+ L S + V +CQVL++
Sbjct: 116 IRDRKYHLRLYRQCCSGRELVDGILA-------LGLGVHSRSQVVGICQVLLDEGA---- 164
Query: 137 GMKKLFKKEKELEFEDSNISLYRFLG 162
L + + F+D + YRF G
Sbjct: 165 ----LCHVKHDWAFQDRDAQFYRFPG 186
>gi|7706643 pleckstrin 2 [Homo sapiens]
Length = 353
Score = 32.3 bits (72), Expect = 0.51
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 11/78 (14%)
Query: 86 TYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPVGMKK---LF 142
TYK F GS VD ++S +S S L+ V L +LM PVG++ +
Sbjct: 154 TYKKTFLGSSLVDWLIS--------NSFTASRLEAVTLASMLMEENFLRPVGVRSMGAIR 205
Query: 143 KKEKELEFEDSNISLYRF 160
+ +F D + +LY F
Sbjct: 206 SGDLAEQFLDDSTALYTF 223
>gi|47578117 DEP domain containing 2 isoform b [Homo sapiens]
Length = 979
Score = 32.3 bits (72), Expect = 0.51
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 68 IHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVL 127
+HSL V I+ + +HL+TYK + +D +++ Q C + + + + GV LC
Sbjct: 489 LHSLFTPV-IRDKDYHLRTYKSVVMANKLIDWLIA---QGDCRTREE-AMIFGVGLCDNG 543
Query: 128 MNHKVFEPVGMKK---LFKKEKELEFEDSNI 155
H V E K LF+ + E E SN+
Sbjct: 544 FMHHVLEKSEFKDEPLLFRFFSDEEMEGSNM 574
Score = 32.0 bits (71), Expect = 0.67
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
Query: 77 IKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPV 136
IK R+ L T+ CF GS+ V S L++ + + +GVHL Q L+ + + V
Sbjct: 396 IKDRKRKLTTFPKCFLGSEFV----SWLLEIGEIHRPE----EGVHLGQALLENGIIHHV 447
Query: 137 GMKKLFKKEKEL 148
K FK E+ L
Sbjct: 448 TDKHQFKPEQML 459
>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
Length = 1606
Score = 32.3 bits (72), Expect = 0.51
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 68 IHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVL 127
+HSL V I+ + +HL+TYK + +D +++ Q C + + + + GV LC
Sbjct: 489 LHSLFTPV-IRDKDYHLRTYKSVVMANKLIDWLIA---QGDCRTREE-AMIFGVGLCDNG 543
Query: 128 MNHKVFEPVGMKK---LFKKEKELEFEDSNI 155
H V E K LF+ + E E SN+
Sbjct: 544 FMHHVLEKSEFKDEPLLFRFFSDEEMEGSNM 574
Score = 32.0 bits (71), Expect = 0.67
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
Query: 77 IKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKGVHLCQVLMNHKVFEPV 136
IK R+ L T+ CF GS+ V S L++ + + +GVHL Q L+ + + V
Sbjct: 396 IKDRKRKLTTFPKCFLGSEFV----SWLLEIGEIHRPE----EGVHLGQALLENGIIHHV 447
Query: 137 GMKKLFKKEKEL 148
K FK E+ L
Sbjct: 448 TDKHQFKPEQML 459
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 30.8 bits (68), Expect = 1.5
Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 3/39 (7%)
Query: 188 YEMISNPLAQEIGEERIEELIHT---INGNPALCPNITV 223
+E + ++ G +R+E ++HT IN +P L PNIT+
Sbjct: 53 HERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITL 91
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 30.8 bits (68), Expect = 1.5
Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 3/39 (7%)
Query: 188 YEMISNPLAQEIGEERIEELIHT---INGNPALCPNITV 223
+E + ++ G +R+E ++HT IN +P L PNIT+
Sbjct: 53 HERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITL 91
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 30.8 bits (68), Expect = 1.5
Identities = 18/42 (42%), Positives = 19/42 (45%), Gaps = 2/42 (4%)
Query: 167 YDCCKRQKDAENEFNETLRPGYEMISNPLAQ--EIGEERIEE 206
Y CC R KD E E RP E P Q E+ ER EE
Sbjct: 257 YCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEE 298
>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
precursor [Homo sapiens]
Length = 906
Score = 30.0 bits (66), Expect = 2.5
Identities = 13/32 (40%), Positives = 21/32 (65%), Gaps = 3/32 (9%)
Query: 195 LAQEIGEERIEELIHT---INGNPALCPNITV 223
+ ++ G +R+E + HT IN +P L PNIT+
Sbjct: 70 IREQYGIQRVEAMFHTLDKINADPVLLPNITL 101
>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
precursor [Homo sapiens]
Length = 1194
Score = 30.0 bits (66), Expect = 2.5
Identities = 13/32 (40%), Positives = 21/32 (65%), Gaps = 3/32 (9%)
Query: 195 LAQEIGEERIEELIHT---INGNPALCPNITV 223
+ ++ G +R+E + HT IN +P L PNIT+
Sbjct: 70 IREQYGIQRVEAMFHTLDKINADPVLLPNITL 101
>gi|148276990 zinc finger and BTB domain containing 38 [Homo
sapiens]
Length = 1195
Score = 29.6 bits (65), Expect = 3.3
Identities = 27/113 (23%), Positives = 45/113 (39%), Gaps = 10/113 (8%)
Query: 115 ISCLKGVHLCQVLMNH-KVFEPVGMKKLFKKEKE---LEFEDSNISLYRFLGNK------ 164
I CL+ +L NH K F + + K+ L+ LYR L K
Sbjct: 519 IFCLETFMTYYILKNHQKSFHAIDHRLSISKKTANGGLKPSVYPYKLYRLLPMKCKRAPY 578
Query: 165 SSYDCCKRQKDAENEFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPAL 217
SY + EN PG ++ NP + E+ ++ ++T+ +PA+
Sbjct: 579 KSYRNSSYENARENSQMNESAPGTYVVQNPHSSELPTLNFQDTVNTLTNSPAI 631
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 28.9 bits (63), Expect = 5.7
Identities = 22/58 (37%), Positives = 24/58 (41%), Gaps = 7/58 (12%)
Query: 234 DVWKEQTLLCLLQLIHLPFLDNILEPPVKTQNLQLNKEEDLVITNTCLDRELIPSLCL 291
+ WK CL H FL+ IL L L KEED LDRE P CL
Sbjct: 318 EAWKVAYFYCLSNNKH--FLEQIL-----VTALTLLKEEDFPNLGCLLDREFRPLSCL 368
>gi|239757132 PREDICTED: hypothetical protein [Homo sapiens]
Length = 583
Score = 28.5 bits (62), Expect = 7.4
Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 16/80 (20%)
Query: 5 EEPARELMAVLLTPRFRRLVSQNELPGPGLNGPSSRNRRDGFCRKRRTGCSGPFQATQLW 64
+ P R A + PR RR S E G G G S+R R G
Sbjct: 129 QRPPRARWAWGVKPRSRRSASAQEPRGDGPRGRSARRRPPG----------------PHL 172
Query: 65 DGIIHSLQAQVEIKRRRHHL 84
G+ LQ Q ++ RR H L
Sbjct: 173 PGVRELLQLQFKLSRRGHRL 192
>gi|239751635 PREDICTED: hypothetical protein XP_002347941 [Homo
sapiens]
Length = 241
Score = 28.5 bits (62), Expect = 7.4
Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 16/80 (20%)
Query: 5 EEPARELMAVLLTPRFRRLVSQNELPGPGLNGPSSRNRRDGFCRKRRTGCSGPFQATQLW 64
+ P R A + PR RR S E G G G S+R R G
Sbjct: 129 QRPPRARWAWGVKPRSRRSASAQEPRGDGPRGRSARRRPPG----------------PHL 172
Query: 65 DGIIHSLQAQVEIKRRRHHL 84
G+ LQ Q ++ RR H L
Sbjct: 173 PGVRELLQLQFKLSRRGHRL 192
>gi|239746147 PREDICTED: hypothetical protein XP_002344287 [Homo
sapiens]
Length = 241
Score = 28.5 bits (62), Expect = 7.4
Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 16/80 (20%)
Query: 5 EEPARELMAVLLTPRFRRLVSQNELPGPGLNGPSSRNRRDGFCRKRRTGCSGPFQATQLW 64
+ P R A + PR RR S E G G G S+R R G
Sbjct: 129 QRPPRARWAWGVKPRSRRSASAQEPRGDGPRGRSARRRPPG----------------PHL 172
Query: 65 DGIIHSLQAQVEIKRRRHHL 84
G+ LQ Q ++ RR H L
Sbjct: 173 PGVRELLQLQFKLSRRGHRL 192
>gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Homo
sapiens]
Length = 381
Score = 28.5 bits (62), Expect = 7.4
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 139 KKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKDAENEFNETLRPGYEMISNPLAQE 198
+KL +KEK+++ E I N +S + + +++EN F E L+ S P +
Sbjct: 179 EKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKED----SIPAPRS 234
Query: 199 IGEERI 204
+G +I
Sbjct: 235 VGSIKI 240
>gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Homo
sapiens]
Length = 376
Score = 28.5 bits (62), Expect = 7.4
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 139 KKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKDAENEFNETLRPGYEMISNPLAQE 198
+KL +KEK+++ E I N +S + + +++EN F E L+ S P +
Sbjct: 179 EKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKED----SIPAPRS 234
Query: 199 IGEERI 204
+G +I
Sbjct: 235 VGSIKI 240
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 28.5 bits (62), Expect = 7.4
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 139 KKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKDAENEFNETLRPGYEMISNPLAQE 198
+KL +KEK+++ E I N +S + + +++EN F E L+ S P +
Sbjct: 179 EKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKED----SIPAPRS 234
Query: 199 IGEERI 204
+G +I
Sbjct: 235 VGSIKI 240
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,851,688
Number of Sequences: 37866
Number of extensions: 610255
Number of successful extensions: 1370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1338
Number of HSP's gapped (non-prelim): 44
length of query: 294
length of database: 18,247,518
effective HSP length: 101
effective length of query: 193
effective length of database: 14,423,052
effective search space: 2783649036
effective search space used: 2783649036
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.