Guide to the Human Genome
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Search of human proteins with 225690491

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225690491 tight junction associated protein 1 isoform b
[Homo sapiens]
         (547 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225690497 tight junction associated protein 1 isoform b [Homo...  1101   0.0  
gi|225690495 tight junction associated protein 1 isoform b [Homo...  1101   0.0  
gi|225690493 tight junction associated protein 1 isoform b [Homo...  1101   0.0  
gi|225690491 tight junction associated protein 1 isoform b [Homo...  1101   0.0  
gi|225690489 tight junction associated protein 1 isoform a [Homo...  1093   0.0  
gi|225690487 tight junction associated protein 1 isoform a [Homo...  1093   0.0  
gi|227497884 brain-enriched guanylate kinase-associated protein ...   172   5e-43
gi|13124765 brain-enriched guanylate kinase-associated protein [...   172   5e-43
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   2e-06
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    50   4e-06
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]                  50   4e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         50   4e-06
gi|55770834 centromere protein F [Homo sapiens]                        50   5e-06
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       50   5e-06
gi|146134388 YLP motif containing 1 [Homo sapiens]                     50   5e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    50   7e-06
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    49   1e-05
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ...    49   2e-05
gi|31982906 cingulin-like 1 [Homo sapiens]                             48   2e-05
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    48   2e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    48   3e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    48   3e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         48   3e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    47   3e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    47   3e-05
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    47   3e-05
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                47   6e-05
gi|156104862 ankyrin repeat domain 38 [Homo sapiens]                   46   1e-04
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]         45   1e-04
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              45   1e-04

>gi|225690497 tight junction associated protein 1 isoform b [Homo
           sapiens]
          Length = 547

 Score = 1101 bits (2848), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
           MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60

Query: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI 120
           RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI
Sbjct: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI 120

Query: 121 KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK 180
           KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK
Sbjct: 121 KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK 180

Query: 181 FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG 240
           FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG
Sbjct: 181 FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG 240

Query: 241 SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF 300
           SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF
Sbjct: 241 SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF 300

Query: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA 360
           EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA
Sbjct: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA 360

Query: 361 RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ 420
           RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ
Sbjct: 361 RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ 420

Query: 421 RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480
           RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI
Sbjct: 421 RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480

Query: 481 SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540
           SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ
Sbjct: 481 SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540

Query: 541 EQGNLLN 547
           EQGNLLN
Sbjct: 541 EQGNLLN 547


>gi|225690495 tight junction associated protein 1 isoform b [Homo
           sapiens]
          Length = 547

 Score = 1101 bits (2848), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
           MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60

Query: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI 120
           RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI
Sbjct: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI 120

Query: 121 KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK 180
           KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK
Sbjct: 121 KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK 180

Query: 181 FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG 240
           FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG
Sbjct: 181 FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG 240

Query: 241 SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF 300
           SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF
Sbjct: 241 SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF 300

Query: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA 360
           EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA
Sbjct: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA 360

Query: 361 RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ 420
           RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ
Sbjct: 361 RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ 420

Query: 421 RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480
           RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI
Sbjct: 421 RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480

Query: 481 SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540
           SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ
Sbjct: 481 SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540

Query: 541 EQGNLLN 547
           EQGNLLN
Sbjct: 541 EQGNLLN 547


>gi|225690493 tight junction associated protein 1 isoform b [Homo
           sapiens]
          Length = 547

 Score = 1101 bits (2848), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
           MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60

Query: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI 120
           RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI
Sbjct: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI 120

Query: 121 KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK 180
           KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK
Sbjct: 121 KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK 180

Query: 181 FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG 240
           FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG
Sbjct: 181 FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG 240

Query: 241 SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF 300
           SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF
Sbjct: 241 SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF 300

Query: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA 360
           EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA
Sbjct: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA 360

Query: 361 RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ 420
           RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ
Sbjct: 361 RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ 420

Query: 421 RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480
           RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI
Sbjct: 421 RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480

Query: 481 SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540
           SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ
Sbjct: 481 SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540

Query: 541 EQGNLLN 547
           EQGNLLN
Sbjct: 541 EQGNLLN 547


>gi|225690491 tight junction associated protein 1 isoform b [Homo
           sapiens]
          Length = 547

 Score = 1101 bits (2848), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
           MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60

Query: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI 120
           RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI
Sbjct: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLI 120

Query: 121 KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK 180
           KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK
Sbjct: 121 KKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHK 180

Query: 181 FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG 240
           FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG
Sbjct: 181 FADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG 240

Query: 241 SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF 300
           SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF
Sbjct: 241 SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF 300

Query: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA 360
           EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA
Sbjct: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA 360

Query: 361 RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ 420
           RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ
Sbjct: 361 RPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQ 420

Query: 421 RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480
           RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI
Sbjct: 421 RTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480

Query: 481 SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540
           SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ
Sbjct: 481 SPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540

Query: 541 EQGNLLN 547
           EQGNLLN
Sbjct: 541 EQGNLLN 547


>gi|225690489 tight junction associated protein 1 isoform a [Homo
           sapiens]
          Length = 557

 Score = 1093 bits (2827), Expect = 0.0
 Identities = 547/557 (98%), Positives = 547/557 (98%), Gaps = 10/557 (1%)

Query: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
           MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60

Query: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL- 119
           RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL 
Sbjct: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120

Query: 120 ---------IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 170
                    IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
Sbjct: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180

Query: 171 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 230
           CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
Sbjct: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240

Query: 231 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 290
           SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
Sbjct: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300

Query: 291 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 350
           PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
Sbjct: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360

Query: 351 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 410
           SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
Sbjct: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420

Query: 411 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 470
           RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP
Sbjct: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480

Query: 471 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 530
           REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
Sbjct: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540

Query: 531 HRKDSLTQAQEQGNLLN 547
           HRKDSLTQAQEQGNLLN
Sbjct: 541 HRKDSLTQAQEQGNLLN 557


>gi|225690487 tight junction associated protein 1 isoform a [Homo
           sapiens]
          Length = 557

 Score = 1093 bits (2827), Expect = 0.0
 Identities = 547/557 (98%), Positives = 547/557 (98%), Gaps = 10/557 (1%)

Query: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
           MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1   MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60

Query: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL- 119
           RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL 
Sbjct: 61  RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120

Query: 120 ---------IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 170
                    IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
Sbjct: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180

Query: 171 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 230
           CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
Sbjct: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240

Query: 231 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 290
           SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
Sbjct: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300

Query: 291 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 350
           PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
Sbjct: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360

Query: 351 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 410
           SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
Sbjct: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420

Query: 411 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 470
           RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP
Sbjct: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480

Query: 471 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 530
           REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
Sbjct: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540

Query: 531 HRKDSLTQAQEQGNLLN 547
           HRKDSLTQAQEQGNLLN
Sbjct: 541 HRKDSLTQAQEQGNLLN 557


>gi|227497884 brain-enriched guanylate kinase-associated protein
           [Homo sapiens]
          Length = 593

 Score =  172 bits (437), Expect = 5e-43
 Identities = 106/254 (41%), Positives = 151/254 (59%), Gaps = 17/254 (6%)

Query: 40  ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99
           E++  LQE+  ELR+RL+  T + E LE E +  +  LE+EL +++EEL+K  +K RR+Q
Sbjct: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61

Query: 100 NSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYR 159
           ++Y A QR NQELEDKL+ + +  E +++ L  EIV L + LL+AK TI+KL E NE YR
Sbjct: 62  SNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYR 121

Query: 160 LDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPT 219
            DCNLA QLL+C++++ R HK ++LP + Q+ V  H+      + P P    A    VPT
Sbjct: 122 KDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLCHPAYADSVPT 180

Query: 220 SVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNG 279
            VIA+VLEKP+   L+S  S ++ R LA          +GV         PG P P   G
Sbjct: 181 CVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EKPG-PRPPYKG 224

Query: 280 ECHSLGTARGSPEE 293
           + +   TA   PEE
Sbjct: 225 DIYCSDTALYCPEE 238


>gi|13124765 brain-enriched guanylate kinase-associated protein
           [Homo sapiens]
          Length = 593

 Score =  172 bits (437), Expect = 5e-43
 Identities = 106/254 (41%), Positives = 151/254 (59%), Gaps = 17/254 (6%)

Query: 40  ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99
           E++  LQE+  ELR+RL+  T + E LE E +  +  LE+EL +++EEL+K  +K RR+Q
Sbjct: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61

Query: 100 NSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYR 159
           ++Y A QR NQELEDKL+ + +  E +++ L  EIV L + LL+AK TI+KL E NE YR
Sbjct: 62  SNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYR 121

Query: 160 LDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPT 219
            DCNLA QLL+C++++ R HK ++LP + Q+ V  H+      + P P    A    VPT
Sbjct: 122 KDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLCHPAYADSVPT 180

Query: 220 SVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNG 279
            VIA+VLEKP+   L+S  S ++ R LA          +GV         PG P P   G
Sbjct: 181 CVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EKPG-PRPPYKG 224

Query: 280 ECHSLGTARGSPEE 293
           + +   TA   PEE
Sbjct: 225 DIYCSDTALYCPEE 238


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 83/356 (23%), Positives = 122/356 (34%), Gaps = 51/356 (14%)

Query: 203  ASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPG 262
            ASP  +PS  P +  P S+ A  L+ P S   +   S SA  P      +     +  P 
Sbjct: 681  ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740

Query: 263  DPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVI 322
             PASPP   S TP P                  PL A   L   P+P    P+ P  +  
Sbjct: 741  PPASPPMSPSATPPPRVP---------------PLLAAPPLQVPPSPPASLPMSPLAKPP 785

Query: 323  EFSEDKVRIP--RNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQP 380
              +   +  P  +  P P  ++  +   S S     S  A P P      +A        
Sbjct: 786  PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845

Query: 381  SPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSP 440
             PA  TL AP    +   D  VS  R  +   P P     R+     + P+L  H + + 
Sbjct: 846  PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 905

Query: 441  ADRDEV--------VQAPSARPEESELL------------------------LPTEPDSG 468
            +  +E+          A ++ P ++EL                         LP  P +G
Sbjct: 906  STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 965

Query: 469  FPREEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKR 524
             P   + L   I   E  +S  P     + GP    + G+A     +    RSPK+
Sbjct: 966  -PGSADGL-CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 90/372 (24%), Positives = 124/372 (33%), Gaps = 60/372 (16%)

Query: 191 MVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDV 250
           M R+   +G E   P PAPS  P    PT    + +              +  RP A   
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSA--- 230

Query: 251 FVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPS 310
                   G    PAS     S TP  +    S  +ARG+P                  +
Sbjct: 231 -------GGGLQRPASRSLSSSATPL-SSPARSGPSARGTPR-----------------A 265

Query: 311 PPHPLYPGRRVIE-FSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTP 369
           P HP  P  + ++     +V  PR    P        +  L+       +ARP P P   
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLATPSPSGTKARPVPPPDNA 323

Query: 370 ASAQAS--PHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRD 427
           A+   +  P   P   PL L+ P+ SA      L S        TPP  A    T     
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS-----PPATPPSQAPPSMTTPPMQ 378

Query: 428 ALPELQR-------HFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 480
           A P LQ        H   SP+     +QAP +    S L   T   S   +      L +
Sbjct: 379 APPSLQTIPPIQVPHSLTSPS-----LQAPPSPLALSSLQATTSLGSPTLQATHSF-LTM 432

Query: 481 SPEEERQSLLPINRGTEEGPGTSHTEG-----RAWPLPSSSRPQRSP--KRMGVHHLHRK 533
           SP + + SL   +R     P +   +       + PL +S  P  SP    + +H L   
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492

Query: 534 DSLTQAQEQGNL 545
            SL     Q  L
Sbjct: 493 SSLASHSPQAPL 504



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 79/323 (24%), Positives = 114/323 (35%), Gaps = 37/323 (11%)

Query: 210 SLAPGAVV--PTSVIARVLEKPESLLLNSAQSGSAG--RPLAEDVFVHVDMSEGVPGDPA 265
           SLAP ++   P S+    LE   SL     Q+ SA    P  E            P  P 
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL 576

Query: 266 SPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFS 325
           + P P +P+        +       P + LP P    L+P  TP P  P       ++  
Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSPP---LSPLATPPPQAPPXLALPPLQAP 633

Query: 326 EDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPL 385
                 P  SPL   +     A+++ L++       PSP    P S  ASP   PS  P 
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPP 692

Query: 386 TLSAPASSASSEEDLLVSWQRAFVDRTPP------PAAVAQRTAFGRDALPELQRHFAHS 439
           + + P+ +A   +          V  +PP      P+A     A    A P LQ      
Sbjct: 693 SQAPPSLAAPPLQ----------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQ----VP 738

Query: 440 PADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQSLLPINRGTEEG 499
           P+       +PSA P      L   P    P      +LP+SP  +     P        
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLPMSPLAKPPPQAP-------- 789

Query: 500 PGTSHTEGRAWPLPSSSRPQRSP 522
           P  +    +A P P +S P ++P
Sbjct: 790 PALATPPLQALPSPPASFPGQAP 812


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 71/256 (27%), Positives = 98/256 (38%), Gaps = 49/256 (19%)

Query: 244 RPLAEDVFVHVDMSEG-VPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEK 302
           R +AE++    +  E  +P  P +PPAP  P P P            SP   L  P    
Sbjct: 384 RAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLP--------PPSTSPPPPLCPPPPPP 435

Query: 303 LNPYPTPSPPHPLYPGRRVIEFSEDKV------RIPRNSPLPNCTYATRQAISLSLVEEG 356
           ++P P PSPP P  P +   E S   V      R     PL     A R+A       EG
Sbjct: 436 VSPPPLPSPPPP--PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAG--PEG 491

Query: 357 SERARPSPVPSTPASAQASPHHQPSPAPLTLS---------APASSASSEEDLLVSWQRA 407
           +  + P+P PST  +    P   P+ AP + +          P  SA S    ++   R 
Sbjct: 492 T--SPPTPTPST--ATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSR--VIKTPRR 545

Query: 408 FVDRTPP-PAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPD 466
           F+D  PP P  V        +  P L+     SP     V Q P+  P  S    PT P 
Sbjct: 546 FMDEDPPKPPKV--------EVSPVLRPPITTSP----PVPQEPA--PVPSPPRAPTPPS 591

Query: 467 SGFPREEEELNLPISP 482
           +  P  E+  ++   P
Sbjct: 592 TPVPLPEKRRSILREP 607



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 57/216 (26%), Positives = 77/216 (35%), Gaps = 41/216 (18%)

Query: 205 PGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDP 264
           P P PS  P A  P S    + EK  S+L              E  F    ++  +P  P
Sbjct: 577 PAPVPS-PPRAPTPPSTPVPLPEKRRSIL-------------REPTFRWTSLTRELPPPP 622

Query: 265 ASPPAPGSPTPQPNGECHS----LGTARGSPEEELPLPAFEK-LNPYPTPSPPHPLYPGR 319
            +PP P +P+P P     S    L  A      E  L  +E  L P P  +P  P     
Sbjct: 623 PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP----- 677

Query: 320 RVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQ 379
                 E +     +SP      A  +   LSL        R +PV +TP  A+ SPH  
Sbjct: 678 ------EPEPPPADDSPAEPEPRAVGRTNHLSL-------PRFAPVVTTPVKAEVSPH-- 722

Query: 380 PSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPP 415
              AP   + P + A   + L     +      PPP
Sbjct: 723 --GAPALSNGPQTQAQLLQPLQALQTQLLPQALPPP 756



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/235 (22%), Positives = 82/235 (34%), Gaps = 31/235 (13%)

Query: 260 VPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGR 319
           VP  P +P  P +P P P      L       E      +  +  P P P+PP P     
Sbjct: 580 VPSPPRAPTPPSTPVPLPEKRRSILR------EPTFRWTSLTRELPPPPPAPPPP----- 628

Query: 320 RVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVE----EGSERARPSPVPSTPASAQAS 375
                       P  SP P    ++R+ + L   +    E   +   S +   P  A  +
Sbjct: 629 ------------PAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEA 676

Query: 376 PHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRH 435
           P  +P PA  + + P   A    + L   + A V  TP  A V+   A      P+ Q  
Sbjct: 677 PEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQ 736

Query: 436 FAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEEL----NLPISPEEER 486
                      +   +  P + +L  P  P    P E+  +    +LP+S  EE+
Sbjct: 737 LLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEK 791



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 93/394 (23%), Positives = 132/394 (33%), Gaps = 91/394 (23%)

Query: 203  ASPGPAPSLAPGAV---------VPTSVIARVLEKPESL--------LLNSAQSGSAG-- 243
            ++PG APS  PGA            T   A  +++P           ++ +   G+AG  
Sbjct: 2043 SAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDR 2102

Query: 244  -RP---LAEDVFVHVDMSEGVPGDPASPPAPGSPTPQP---NGECHSLGTARGSPEEE-- 294
             RP   L  ++   V  + G PGD  + P   S  P P   NG   S G    SP +   
Sbjct: 2103 ARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLT-ASPADPTR 2161

Query: 295  ----LP-LPAFEKLNPYPTPSPPHPLYP--------GRRVIEFSEDKVRIP---RNSPLP 338
                LP  P    L+  P P PP P           G+  ++ + +   +P   +  PLP
Sbjct: 2162 TFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLP 2221

Query: 339  NCTYATRQAISLSLVEEGSERARPSPVPST-PASAQASPHHQPSPAPLTLSAPASSAS-S 396
                      ++S     S    P P+    P      P   P P PLTL   +  AS  
Sbjct: 2222 P---------TISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPP 2272

Query: 397  EEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEE 456
             + + V     F  R+PP     +      D           +  D  +V    S     
Sbjct: 2273 RQAIRVKRVSTFSGRSPPAPPPYKAPRLDED---------GEASEDTPQVPGLGSGGFSR 2323

Query: 457  SELLLPTEP---DSGFPREEEELNLPISPEEERQSLLPINRGTEEGPGT----------- 502
              +  PT     D   P E      P  P +ER  LLP+    E+GP             
Sbjct: 2324 VRMKTPTVRGVLDLDRPGEPAGEESP-GPLQERSPLLPL---PEDGPPQVPDGPPDLLLE 2379

Query: 503  ---SHTEGRA-----WPLPSSSRPQRSPKRMGVH 528
                H  G A      P     +  ++PKR G H
Sbjct: 2380 SQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPH 2413



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 52/224 (23%), Positives = 74/224 (33%), Gaps = 46/224 (20%)

Query: 265 ASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEK----------LNPYPTPSPPHP 314
           A P     PTP P+       TA G P E+ P  A +           + P  +      
Sbjct: 487 AGPEGTSPPTPTPS-------TATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRV 539

Query: 315 LYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQA 374
           +   RR ++  ED  + P+    P      R  I+ S            PVP  PA    
Sbjct: 540 IKTPRRFMD--EDPPKPPKVEVSP----VLRPPITTS-----------PPVPQEPAPVP- 581

Query: 375 SPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQR 434
           SP   P+P    +  P    S   +    W     +  PPP A     A      P    
Sbjct: 582 SPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA--- 638

Query: 435 HFAHSPADRDEVVQAPSARPEESELLL----PTEPDSGFPREEE 474
               + + R  +++AP   P E+ L +     T P  G P   E
Sbjct: 639 ----TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPE 678



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 40/124 (32%), Positives = 51/124 (41%), Gaps = 25/124 (20%)

Query: 203  ASPGP-APSLAPGAVVPTS-VIARV-LEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEG 259
            ASPGP  P    GA  P   V+A    E+ +SLL   +      +  + D+F   D SE 
Sbjct: 1038 ASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSE- 1096

Query: 260  VPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLN--PYPTPSPPHPLYP 317
                P  PPAP   TP+               E ELPLP  E+ +    PT  P   L  
Sbjct: 1097 ----PGGPPAPRRRTPR---------------ENELPLPEPEEQSRPRKPTLQPVLQLKA 1137

Query: 318  GRRV 321
             RR+
Sbjct: 1138 RRRL 1141


>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
          Length = 1499

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 91/363 (25%), Positives = 131/363 (36%), Gaps = 55/363 (15%)

Query: 205  PGPAPSLAPGAV--VPTSVIARVLEKPESLLLNSAQSGSAGR-------------PLAED 249
            P P  S  PG V   P   + R   +P  L ++  Q GS G              PL   
Sbjct: 891  PLPPASNPPGTVHSAPNRGLGR---RPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTS 947

Query: 250  VFVHVDM----SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNP 305
               ++      S+ VP   A+PP P   +PQ  G   S+ +  GSP   L  P+    +P
Sbjct: 948  PSANLKSPQTPSQMVPLPSANPPGP-LKSPQVLGSSLSVRSPTGSPSR-LKSPSMAVPSP 1005

Query: 306  YPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYAT------RQAISLSLVEEGSER 359
                SP   + P   V +  +  + +  ++ L N    T      R + S       S  
Sbjct: 1006 GWVASPKTAM-PSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGL 1064

Query: 360  ARPS--------PVPS-TPAS---AQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRA 407
              PS        P PS  P S    Q S +  PS  PL  +A  + A+S+++LL    R 
Sbjct: 1065 MNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLP--DRP 1122

Query: 408  FVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAP-SARPEESELLLPTEPD 466
             +   PPP       +  + +   L    A SP   +   Q P S  P  + L  PT   
Sbjct: 1123 LLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLG 1182

Query: 467  SGFPREEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMG 526
            S         N+P+ P  +     P N       G         P+PSSS+    P R+ 
Sbjct: 1183 S---------NIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQ 1233

Query: 527  VHH 529
              H
Sbjct: 1234 QPH 1236


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 73/281 (25%), Positives = 101/281 (35%), Gaps = 54/281 (19%)

Query: 264 PASPPAPG-SPTPQPNGECHSLGTARGSPEEELPLPAFEK-LNPYPTP-----SPPHPLY 316
           PA PP    +PTP P     S    R SP      P  ++  +P P P     SPP P  
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP-- 620

Query: 317 PGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASP 376
           P RR       K R+  + P    +    +  S SL  +  + + PS       S Q + 
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK 680

Query: 377 HHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHF 436
            H PSP P    AP +S+S                 PPP          R A    QR  
Sbjct: 681 RHSPSPRP---RAPQTSSS-----------------PPPVR--------RGASSSPQRRQ 712

Query: 437 AHSPADR-----------DEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEE 485
           + SP+ R            ++ +A S  P+    +  +   SG P  E     P +P   
Sbjct: 713 SPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSP--EPAAKKPPAPPSP 770

Query: 486 RQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMG 526
            QS  P    T   P     + ++ P PS S P+ S +  G
Sbjct: 771 VQSQSP---STNWSPAVPVKKAKS-PTPSPSPPRNSDQEGG 807


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 14/122 (11%)

Query: 42   MKLLQEENEELRRRLASATRRTEAL---ERELEIGQDCLELELGQSREELDKFKDKFRRL 98
            M++LQ + +EL  R+A+     EA    E+ L    +CLELE  Q  + LD+ K+ +  L
Sbjct: 2440 MEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2499

Query: 99   QNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERY 158
            Q+S        QE+ED    L KK        D EI  L N++ D +  ++KL ++   +
Sbjct: 2500 QSSVNG---LIQEVEDGKQKLEKK--------DEEISRLKNQIQDQEQLVSKLSQVEGEH 2548

Query: 159  RL 160
            +L
Sbjct: 2549 QL 2550



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 34/168 (20%), Positives = 79/168 (47%), Gaps = 8/168 (4%)

Query: 13  KAPPEHRELRLEIPGSRLEQEEPLTDAERMK--LLQEENEELRRRLASATRRTEALEREL 70
           K   + R+ +L+   + L++++   + E+ +   L+ EN+ L     S  +  + +  EL
Sbjct: 31  KKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHEL 90

Query: 71  EIGQDCLELELGQ---SREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDR 127
           ++ +  +  + GQ    +++++K + + +R ++    SQ+  Q  +  L+      ++  
Sbjct: 91  QVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFT 150

Query: 128 KTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNL-AVQLLKCNKS 174
             L        +K  D K   NK  E+ ER RL+  + A+Q  K +++
Sbjct: 151 TPLTPSQYYSGSKYEDLKEKYNK--EVEERKRLEAEVKALQAKKASQT 196



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 7/133 (5%)

Query: 32  QEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKF 91
           QEE        + L +E  +++ RL    ++ + +   L+   D L     Q    L++F
Sbjct: 397 QEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEF 456

Query: 92  KDKFRRLQNSYTASQRTNQELEDKLHTLIK-----KAEMDRKTLDWEIVELTNKLLDAKN 146
           K K  R + ++ ASQ    EL   +  + K     K+  ++K    E+  L  +L + K 
Sbjct: 457 KQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAR--EVCHLEAELKNIKQ 514

Query: 147 TINKLEELNERYR 159
            +N+ +   E  +
Sbjct: 515 CLNQSQNFAEEMK 527



 Score = 36.6 bits (83), Expect = 0.061
 Identities = 37/165 (22%), Positives = 70/165 (42%), Gaps = 15/165 (9%)

Query: 43   KLLQEENEELRRRLASATRRTEALERELEIGQDCLEL----------ELGQSREELDKFK 92
            +L +E+N ELR       ++ + L+ +    QD LE+          EL  ++ +   F 
Sbjct: 2549 QLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFV 2608

Query: 93   DKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLE 152
            +K  ++    T  QR   E+  K   L ++   ++  L  E+  L  ++  +K+ + +L 
Sbjct: 2609 EKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELT 2668

Query: 153  ELNERYR--LDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKH 195
              N   +  LDC    Q+ K  K      + A+    L +  +KH
Sbjct: 2669 LENSELKKSLDCMHKDQVEKEGKV---REEIAEYQLRLHEAEKKH 2710



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 39/149 (26%), Positives = 61/149 (40%), Gaps = 26/149 (17%)

Query: 15   PP--EHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEI 72
            PP  E  +LR  I   R   E    D ++   + ++ +E          R E LERELEI
Sbjct: 2291 PPIEEEHQLRNSIEKLRARLE---ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEI 2347

Query: 73   G---QDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKT 129
                Q+   LE   S+ E++  K K   +  S                  ++  E+D  T
Sbjct: 2348 ARTNQEHAALEAENSKGEVETLKAKIEGMTQS------------------LRGLELDVVT 2389

Query: 130  LDWEIVELTNKLLDAKNTINKLEELNERY 158
            +  E   LTN+L   +  I++LE +N  +
Sbjct: 2390 IRSEKENLTNELQKEQERISELEIINSSF 2418



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 42/173 (24%), Positives = 70/173 (40%), Gaps = 31/173 (17%)

Query: 30   LEQEEPLTDAERMKLLQEENE------ELRRRLASATRRTEALERELEIGQDCLELELGQ 83
            LE E  LT  ++M  +++ N+      EL+R +    ++T  L+ EL   ++ L  EL  
Sbjct: 2593 LENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQL 2652

Query: 84   SREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLD 143
              EE+   KD+ + L          N EL+  L  + K        +  EI E   +L +
Sbjct: 2653 LLEEIKSSKDQLKEL-------TLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHE 2705

Query: 144  A-KNTINKLEELNERYRLDC-----------------NLAVQLLKCNKSHFRN 178
            A K     L + N++Y ++                   L + LLK +K    N
Sbjct: 2706 AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNN 2758



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 33/145 (22%), Positives = 66/145 (45%), Gaps = 18/145 (12%)

Query: 28   SRLEQEEPLTDAERMK-LLQEENEELRRRLASATRR----TEALEREL-EIGQDCLEL-- 79
            ++ E E  +    + K LL +E+E L+ RL+ +       ++ALE  L E G+  L L  
Sbjct: 2050 TKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSS 2109

Query: 80   ---ELGQSREELDKFKDKFR-------RLQNSYTASQRTNQELEDKLHTLIKKAEMDRKT 129
               E+ Q R  ++K + +          +       +R N  L+DK+  L ++ +M  + 
Sbjct: 2110 TQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEEN 2169

Query: 130  LDWEIVELTNKLLDAKNTINKLEEL 154
             +  I++  N   + +    ++EE+
Sbjct: 2170 QELVILDAENSKAEVETLKTQIEEM 2194



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 19/110 (17%)

Query: 45  LQEENEELRRRLASATRRTEALERELEIGQ----------------DCLELE--LGQSRE 86
           L+ +N+ELR ++     R +  E+E++ GQ                + +E E  L + R+
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMK-GQVNKFQELQLQLEKAKVELIEKEKVLNKCRD 341

Query: 87  ELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVE 136
           EL +   ++ +    YTA ++  ++L + L    + AE  R +L+ +I E
Sbjct: 342 ELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKE 391



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 10/125 (8%)

Query: 31  EQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDK 90
           E EE L  AE+M   Q    E  +R++     T A +  +      LE       +EL  
Sbjct: 862 EIEENLMKAEQMH--QSFVAETSQRISKLQEDTSAHQNVVAETLSALE----NKEKELQL 915

Query: 91  FKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINK 150
             DK    Q      +++N  LED L    K+ ++  +TL  E  E+++ +   K  I +
Sbjct: 916 LNDKVETEQAEIQELKKSNHLLEDSL----KELQLLSETLSLEKKEMSSIISLNKREIEE 971

Query: 151 LEELN 155
           L + N
Sbjct: 972 LTQEN 976


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 89/339 (26%), Positives = 125/339 (36%), Gaps = 63/339 (18%)

Query: 198 SGQEAASPGPAPSLAPGAVV---PTSVIARVLEKPESLLLNSAQSGSAGRPLAEDV--FV 252
           S +E      A ++A  +V    P +  A ++E P  +   SA+   +   LAE +    
Sbjct: 296 STEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSA 355

Query: 253 HVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPP 312
               SE  P +   PPA  SP+ +  GE  S  +A+ +P E  PLPA   L   P    P
Sbjct: 356 EESPSEEPPAEILPPPAEKSPSVELLGEIRS-PSAQKAPIEVQPLPAEGALEEAPAKVEP 414

Query: 313 ----------HPLYPGR------------RVIEFSEDKVRIPRNSPLPNCTYATRQAISL 350
                      PL P                +E   ++      SPLP  T A   +  +
Sbjct: 415 PTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEI 474

Query: 351 SLVEEGSERARPSPVPSTPASAQ--------ASPHHQPSPAPLTLSAPASSASSEEDLLV 402
            L+      A   P   TPA A+        A   H    +PL     A  AS+E  LL 
Sbjct: 475 QLL-----AATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLA 529

Query: 403 SWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEE-SELLL 461
           + + A  D TP  A         +  L E +     +PA+    VQ+PSA+     E  L
Sbjct: 530 AIE-APADETPAEA---------QSPLSE-ETSAEEAPAE----VQSPSAKGVSIEEAPL 574

Query: 462 PTEPDSGFPREEEELNLPISPEEERQSLLPINRGTEEGP 500
             +P SG     EE +  I      Q L       EE P
Sbjct: 575 ELQPPSGEETTAEEASAAI------QLLAATEASAEEAP 607



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 45/175 (25%), Positives = 59/175 (33%), Gaps = 36/175 (20%)

Query: 352 LVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDR 411
           LVEE + +A P P   T    Q S    P        A A++A +E  + V         
Sbjct: 273 LVEEATAKAEPRPAEETHVQVQPSTEETP-------DAEAATAVAENSVKVQ-------- 317

Query: 412 TPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEES-ELLLPTEPDSGFP 470
            PPPA  A    F               PA+    +Q PSA    S ELL    P S   
Sbjct: 318 -PPPAEEAPLVEF---------------PAE----IQPPSAEESPSVELLAEILPPSAEE 357

Query: 471 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRM 525
              EE    I P    +S      G    P          PLP+    + +P ++
Sbjct: 358 SPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKV 412



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 58/240 (24%), Positives = 87/240 (36%), Gaps = 49/240 (20%)

Query: 201 EAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGV 260
           E  SP    + A  A     ++A + E P       AQS     PL+E+       +E  
Sbjct: 507 EVQSPLAEETTAEEASAEIQLLAAI-EAPADETPAEAQS-----PLSEET-----SAEEA 555

Query: 261 PGDPASPPAPGSPTPQ-------PNGE--------------CHSLGTARGSPEEELPLPA 299
           P +  SP A G    +       P+GE                +  +A  +P E  P PA
Sbjct: 556 PAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPA 615

Query: 300 FE---KLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEG 356
            E   ++ P P    P  + P     E +  +V+ P     P         +     EE 
Sbjct: 616 EEAPAEVQPPPAEEAPAEVQPPPA--EEAPAEVQPPPAEEAP-------AEVQPPPAEEA 666

Query: 357 SERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPA 416
               +P P    PA  Q+ P  + +P   TL+A  S  + +    V  + A VD+  PPA
Sbjct: 667 PAEVQPPPAEEAPAEVQSLPAEE-TPIEETLAAVHSPPADD----VPAEEASVDKHSPPA 721


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 90/416 (21%), Positives = 154/416 (37%), Gaps = 79/416 (18%)

Query: 15  PPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRR------------LASATRR 62
           PP + E+   +P    + E+P  DA R+K LQ      ++             +   T+ 
Sbjct: 354 PPPNEEVPPPLPPEEPQSEDPEEDA-RLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQL 412

Query: 63  TEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKK 122
            + L++  +I Q    ++      +L  ++ + ++ Q+ Y   +R  Q  E++LH+   K
Sbjct: 413 QQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHK 472

Query: 123 AEMDRKTLDWEI----VELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRN 178
            ++      W+     ++ T   L  K  +N  + +  +Y  + ++    +         
Sbjct: 473 DQLQEYEKQWKTWQGHMKATQSYLQEK--VNSFQNMKNQYMGNMSMPPPFV--------- 521

Query: 179 HKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQ 238
             ++ +P  L  M    L     +  P   P   P  V P  +   V+  P SL  +   
Sbjct: 522 -PYSQMPPPLPTMPPPVL---PPSLPPPVMPPALPATVPPPGMPPPVM--PPSLPTSVPP 575

Query: 239 SGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLP 298
            G           +   +S   P     PP+  S  P P     SL +   +P   +PLP
Sbjct: 576 PG-----------MPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSST--APPPVMPLP 622

Query: 299 AFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSE 358
                 P P   PP                  +P+  P P  T A     S S   +  E
Sbjct: 623 PLSSATPPPGIPPP-----------------GVPQGIP-PQLTAAPVPPASSSQSSQVPE 664

Query: 359 RARPS--PVPSTPASAQASPHHQP-----------SPAPLTLSA-PASSASSEEDL 400
           + RP+  P P +  SA  + +H P           S APL+ SA P SS SS++ L
Sbjct: 665 KPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL 720



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 64/285 (22%), Positives = 94/285 (32%), Gaps = 42/285 (14%)

Query: 256 MSEGVPGDPASPPAPGSPTPQP-------------------NGECHSLGTARGSPEEELP 296
           M  G  GD   PP P  P P P                   +G    +     SP E  P
Sbjct: 92  MPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPP 151

Query: 297 LPAFEKLNP----YPTPSPPHPLYPGRRVIEFSEDKVRIPRNSP------LPNCTYATRQ 346
           +P    + P     P P PP   YP      +       P  SP       P  +Y++  
Sbjct: 152 VPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSS 211

Query: 347 AISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLL----- 401
           + S S +   S+   PS   S    +Q     Q    P   + P +  + +++ L     
Sbjct: 212 SSSQSYLSH-SQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAK 270

Query: 402 -VSWQRAFVDRTPPPAAVA----QRTAFGRDALPELQRHFAHSPA-DRDEVVQAPSARPE 455
             S ++      P P+ +     Q+  + +  L   QR   H P   +  VV   +  P 
Sbjct: 271 NKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPV 330

Query: 456 ESELLLPTEPDSGFPREEEELNLPISPEEERQSLLPINRGTEEGP 500
           + E+ +P           EE  LP  P EE    LP      E P
Sbjct: 331 KEEVTVPATSQVPESPSSEEPPLP-PPNEEVPPPLPPEEPQSEDP 374



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 34/137 (24%), Positives = 49/137 (35%), Gaps = 15/137 (10%)

Query: 264  PASPPAPGS-PTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVI 322
            P   P PGS   P P G+         +P     +P      P P P PP PL P   VI
Sbjct: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI 1562

Query: 323  EFSEDKVRIPRNSPLPNCTYATRQAISL--SLVEEGSE---RARPSPVPSTPASAQASPH 377
            +        P+ S +    +       L  +  E+G     ++  + +PS P       H
Sbjct: 1563 K--------PQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVH 1614

Query: 378  HQ-PSPAPLTLSAPASS 393
               P P P+ +  P  S
Sbjct: 1615 SSIPPPGPVPMGMPPMS 1631



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 57/284 (20%), Positives = 87/284 (30%), Gaps = 63/284 (22%)

Query: 257 SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEE-------ELPLPAFEKLNPY--- 306
           S   P  P  PP P +      G  +S  T   +P         E  L   ++L      
Sbjct: 11  SSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQK 70

Query: 307 ------------PTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVE 354
                       P P PP P+ PG    ++      +P   P P  +Y  +Q     ++ 
Sbjct: 71  QMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMP-PPPGPALSYQKQQQYKHQML- 128

Query: 355 EGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPP 414
                 R  P    P   ++ P   P P P +   P+ S              ++    P
Sbjct: 129 ---HHQRDGPPGLVPMELESPPESPPVP-PGSYMPPSQS--------------YMPPPQP 170

Query: 415 PAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEE 474
           P +    T+  +  LP  Q               +PS  P     L PT      P    
Sbjct: 171 PPSYYPPTS-SQPYLPPAQ--------------PSPSQSPPSQSYLAPT------PSYSS 209

Query: 475 ELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRP 518
             +   S     QS LP ++ +   P   H++ +    P  S P
Sbjct: 210 SSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAP 253


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 88/341 (25%), Positives = 127/341 (37%), Gaps = 59/341 (17%)

Query: 205 PGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDP 264
           P  +P   P    PTS        PE+  L+         PL E + +   + E     P
Sbjct: 444 PEESPLSPPPEESPTS------PPPEASRLSPPPEELPASPLPEALHLSRPLEES----P 493

Query: 265 ASPP---APGSPTPQPNGECHSLGTARGSPEEELPLPAFEK-LNPYPTPSPPHPLYPGRR 320
            SPP   +P SP P+ +       +    PEE  P PA E  L+P P  SP  P +    
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF---- 549

Query: 321 VIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARP---SPVPSTPASAQASPH 377
                E+    P    LP  T    +A  LS   E S  + P   SP+   P +++  P 
Sbjct: 550 -----EESPLSPPPEELP--TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602

Query: 378 HQPSP-------APLTLSAPASSASSE-EDLLVSWQRAFVDRTPPP--AAVAQRTAFGRD 427
            + SP       +PL+    AS  S   ED  +S        +PPP  + ++      R 
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662

Query: 428 ALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQ 487
           + P  +   +  P +      +P++ P E+  L P   DS      E+      PE+   
Sbjct: 663 SPPPEESPLSPPPEE------SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716

Query: 488 SLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVH 528
           S LP+    EE P           LP    PQ  P+  G H
Sbjct: 717 S-LPL----EESP----------LLPLPEEPQLCPRSEGPH 742



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 86/339 (25%), Positives = 119/339 (35%), Gaps = 50/339 (14%)

Query: 205 PGPAPSLAPGAVVPTS--------VIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDM 256
           PG  P+  P A+            V +   ++P  L   +   G AG  L   +     +
Sbjct: 377 PGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQL--EAPL 434

Query: 257 SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPE-EELPLPAFEKLNPYPTPSPPHPL 315
           +E +P  P    +P SP P+ +        +R SP  EELP     +      P    PL
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL 494

Query: 316 YPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASA--Q 373
            P       S      P +SP     ++  +   LS  EE      PSP   TP S   +
Sbjct: 495 SPPPEESPLSPP----PESSP-----FSPLEESPLSPPEESP----PSPALETPLSPPPE 541

Query: 374 ASPHHQP------SPAPLTL-SAPASSASS----EEDLLVSWQRAFVDRTPPPAAVAQRT 422
           ASP   P      SP P  L ++P   AS      E+  +S        +PPP A     
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFP 601

Query: 423 AFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISP 482
            F    L         SP   +    +P + P E+  L P   DS      EE  +   P
Sbjct: 602 PFEESPL---------SPPPEE----SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648

Query: 483 EEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRS 521
           E  R S LP+       P  S         P+S  P+ S
Sbjct: 649 EVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 71/273 (26%), Positives = 89/273 (32%), Gaps = 27/273 (9%)

Query: 264 PASPP---APGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRR 320
           P SPP   +P SP P+ +        +R SP      P    L+P P  SP  P     R
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP-----PEESPLSPPPEESPTSPPPEASR 688

Query: 321 VIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQAS--PHH 378
           +    ED    P     P         +SL L     E +   P+P  P     S  PH 
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL-----EESPLLPLPEEPQLCPRSEGPHL 743

Query: 379 QPSPAPLTLSA----PASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQR 434
            P P    LS     P  S  +EE  L            P        A G    P+ + 
Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803

Query: 435 HFAHSPADRDEVVQAP-----SARPEESELLLPTEPDSGFPREEEELNLPISPEEERQSL 489
                  +   +   P     S +PEES L   +E     PR EE     +SPE E+  L
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEES---HLSPELEKPPL 860

Query: 490 LPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSP 522
            P      E PG           P    P  SP
Sbjct: 861 SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSP 893



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 94/387 (24%), Positives = 140/387 (36%), Gaps = 66/387 (17%)

Query: 201 EAASPGPAPSLAPGAVVPTSV-IARVLEK------PESLLLNSAQSGSAGRPLAEDVFVH 253
           EA+   P P   P + +P ++ ++R LE+      PE   L+     S   PL E     
Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522

Query: 254 VDMSEGVPG-----------DPASPP---APGSPTPQ-----PNGECHSLG-----TARG 289
            + S   P             P SPP   +P SP P+     P  E   L      +   
Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582

Query: 290 SPEEELPL----------PAFEK--LNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRN--- 334
            P EE P+          P FE+  L+P P  SP  P     R+    ED    P     
Sbjct: 583 PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642

Query: 335 --SPLPNCTYATRQAI--SLSLVEEGSERARP---SPVPSTPASAQASPHHQPSP-APLT 386
             SP P  +  +   +   LS   E S  + P   SP    P +++ SP  + SP +P  
Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702

Query: 387 LSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEV 446
             +PAS    +  + +  + + +   P    +  R+     +    + H +  P +    
Sbjct: 703 EDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762

Query: 447 VQAP----SARPEESELLLPTEPDSGFPREE--------EELNLPISPEEERQSLLPINR 494
            QA     S +PEE  L    E     P+ E        EEL+L    EE   S +P   
Sbjct: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEP 822

Query: 495 GTEEGPGTSHTEGRAWPLPSSSRPQRS 521
                P  SH   ++     S RP+ S
Sbjct: 823 CLSPQPEESHLSPQSEEPCLSPRPEES 849



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 79/309 (25%), Positives = 105/309 (33%), Gaps = 58/309 (18%)

Query: 201 EAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGV 260
           E +   P P ++   + P  V++R+   PE   L+     S   P  E       +S   
Sbjct: 640 EESPMSPPPEVS--RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS----RLSPPP 693

Query: 261 PGDPASPPAPGSP-TPQPNGECHSLGTARGSPEEE---LPLPAFEKL-----NPYPTPSP 311
              P SPP   SP +P P     SL      P EE   LPLP   +L      P+ +P P
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSL------PLEESPLLPLPEEPQLCPRSEGPHLSPRP 747

Query: 312 PHPLYPGRRVIEFSEDKVRIPRNSPLPN--CTYATRQAISLSLVEEG------------- 356
             P    R        +   P  SP P   C  A  +   LS   EG             
Sbjct: 748 EEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS 807

Query: 357 --SERARPSPVPSTPA----------SAQA-----SPHHQPSPAPLTLSAPASSASSEED 399
             +E    SPVP  P           S Q+     SP  + S     L  P  S   E+ 
Sbjct: 808 PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP 867

Query: 400 LLVSWQRAFVDRTP---PPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEE 456
                Q    +  P   PP   +     G  AL E       SP   +E+  +PS  P  
Sbjct: 868 PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP-PLSPLP-EELPLSPSGEPSL 925

Query: 457 SELLLPTEP 465
           S  L+P +P
Sbjct: 926 SPQLMPPDP 934



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 67/269 (24%), Positives = 97/269 (36%), Gaps = 37/269 (13%)

Query: 268  PAPGSPTPQPNGECHSL----GTARGSPEEELPLPAF---EKLNPYPTPSPPHPLYP-GR 319
            P PG P P P G    +       +G      P P     ++   YP    PH L P G 
Sbjct: 2862 PGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGL 2921

Query: 320  RVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQ 379
            R +  S    + P   P P         ++ SL      +    P      +   S    
Sbjct: 2922 RGLAVSGLPPQKPSAPPAPE--------LNNSLHPTPHTKGPTLPTGLELVNRPPSSTEL 2973

Query: 380  PSPAPLTLSA---PASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHF 436
              P PL L A   P      ++D   + +    D       +    A G D L  L+   
Sbjct: 2974 GRPNPLALEAGKLPCEDPELDDD-FDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLE 3032

Query: 437  AHSPADRDEVVQAPSARPEESELLLPTEP--DSGFPRE--EEELNLPISPEE--ERQSLL 490
             + P   D+++       +E +LL  T+P  D+G  ++   E L L  S  E  ER++LL
Sbjct: 3033 TNDP-HLDDLLNG-----DEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALL 3086

Query: 491  PINRGTEEGPGTSHTEGRAWPLPSSSRPQ 519
               RG E  PG    E R  P   +S P+
Sbjct: 3087 ---RGVE--PGPLGPEERPPPAADASEPR 3110


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 91/405 (22%), Positives = 139/405 (34%), Gaps = 87/405 (21%)

Query: 202 AASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVP 261
           A +P PAP++A  A   T+  A       +    SA + +   P A D+F   D+ E  P
Sbjct: 520 ATAPSPAPAVAAAAAATTAATAAAT----TTTTTSAATATTAPP-ALDIFG--DLFESTP 572

Query: 262 GDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFE------KLNPYPTPSPPHPL 315
              A+P     P   P+ +  S       P+   P+P          ++ +  PSP    
Sbjct: 573 EVAAAP----KPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTA 628

Query: 316 YPGR----RVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEE-GSERARPSPVPSTPA 370
            P +     VI+   D      + P P    A+  + S  L+   G     PSP P TPA
Sbjct: 629 SPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPA 688

Query: 371 SAQASPHHQPSPAPLTLSAPASSASSEEDLLV--------------SWQRAFVDRTPPPA 416
                   QP+      + P++S+SS  D  V              + Q A V   PP  
Sbjct: 689 QNNLL---QPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSP 745

Query: 417 AVAQRTAFGRD---ALPELQRHFAHS---------------------------------- 439
           A+A   A G D   +L  L  +   S                                  
Sbjct: 746 AMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWS 805

Query: 440 -----PADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQSLLPINR 494
                 A     V   S+ P  +      +P +GF        +P+ P++      P+ R
Sbjct: 806 AGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMR 865

Query: 495 ---GTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSL 536
              G    PGT  +     P P+S  P++ P +  +  L+ KD L
Sbjct: 866 PPFGAAAVPGTQLSPS---PTPASQSPKKPPAKDPLADLNIKDFL 907



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 71/299 (23%), Positives = 104/299 (34%), Gaps = 38/299 (12%)

Query: 202 AASPGPAPSLAPGAVVPTSV--IARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEG 259
           AASPG AP+ + GA  P +   +A  L+        +   GSA      D+F        
Sbjct: 445 AASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETS 504

Query: 260 VPG-DPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPG 318
           VP   P +  AP  P   P+        A  +             +     + P  L   
Sbjct: 505 VPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIF 564

Query: 319 RRVIEFSEDKVRIPRNSPLPNCTYATRQAIS-----LSLVEEGSERAR-------PSPVP 366
             + E + +    P+    P+    +  A S      S V E S  A         +P P
Sbjct: 565 GDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSP 624

Query: 367 STPAS---------------AQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDR 411
           +T AS               A  S   +P PA    S  ASS+S+  DLL  +  +F+  
Sbjct: 625 ATTASPAKVDSSGVIDLFGDAFGSSASEPQPA----SQAASSSSASADLLAGFGGSFMAP 680

Query: 412 TPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 470
           +P P   AQ         P  +  F  +P+        PS      +LL+PT   +G P
Sbjct: 681 SPSPVTPAQNNLL----QPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQP 735


>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
            sapiens]
          Length = 1386

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 82/303 (27%), Positives = 110/303 (36%), Gaps = 62/303 (20%)

Query: 264  PASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF-EKLNPYPTPSPPHPLYPGRRVI 322
            P  P       P  +G C    + R +P    P P++ ++     TPSPP P  P   + 
Sbjct: 1115 PPMPERSHLTEPSSSGGCLVTPSRRETPS---PTPSYGQQSTATLTPSPPDPPQPPTDMP 1171

Query: 323  EFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSP 382
               +   R+P     P         +S+S    G   ARP+ + + PA   ASPH  PSP
Sbjct: 1172 HLHQMPRRVPLGPSSP---------LSVSQPMLGIREARPAGLGAGPA---ASPHLSPSP 1219

Query: 383  APLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPAD 442
            AP T    ASSA        +WQ    + TPP      R      ALP  +    +SP D
Sbjct: 1220 APST----ASSAPGR-----TWQ-GNGEMTPPLQGPRARFRKKPKALPYRRE---NSPGD 1266

Query: 443  RDEVVQAPSARPEESELLLPTE------------PDSGFPREEEELNLP----ISPEEE- 485
                +  P   P E E     E              SG  +  + + L     + P+EE 
Sbjct: 1267 ----LPPPPLPPPEEEASWALELRAAGSMSSLERERSGERKAVQAVPLAAQRVLHPDEEA 1322

Query: 486  -----RQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 540
                 R S L   +GT           R     SSSR  R P R       R  S +Q+Q
Sbjct: 1323 WLPYSRPSFLSRGQGTSTCSTAGSNSSRG---SSSSRGSRGPGR----SRSRSQSRSQSQ 1375

Query: 541  EQG 543
              G
Sbjct: 1376 RPG 1378


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/140 (27%), Positives = 76/140 (54%), Gaps = 17/140 (12%)

Query: 31  EQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDK 90
           EQ++  T+  R+KLLQEENE+L+ R     RR   L+R++E     L+ +  +++E L K
Sbjct: 814 EQDQAGTEM-RVKLLQEENEKLQGRSEELERRVAQLQRQIE----DLKGDEAKAKETLKK 868

Query: 91  FKDKFRRLQNSYTASQRTNQE-------LEDKLHTL---IKKAEMDRKTLDWEIVELTNK 140
           ++ + R+L+ +   +++  +E       LE++L      + +   ++K L  ++ E + +
Sbjct: 869 YEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQ 928

Query: 141 LLDAKNTINKLEELNERYRL 160
               +   N++E  NER+ L
Sbjct: 929 KEQLRRLKNEME--NERWHL 946



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 37/133 (27%), Positives = 63/133 (47%), Gaps = 18/133 (13%)

Query: 19  RELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLE 78
           R+L+LE+   +  +EE     ERM+      EELR +          L++ LE  +    
Sbjct: 628 RQLQLEVKNQQNIKEE----RERMRA---NLEELRSQHNEKVEENSTLQQRLEESEG--- 677

Query: 79  LELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELT 138
            EL ++ EEL  F+ K  R Q+     Q   ++L+D+L  +  + +  +++ D E   L 
Sbjct: 678 -ELRKNLEEL--FQVKMEREQH-----QTEIRDLQDQLSEMHDELDSAKRSEDREKGALI 729

Query: 139 NKLLDAKNTINKL 151
            +LL AK  +  L
Sbjct: 730 EELLQAKQDLQDL 742



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 29/121 (23%), Positives = 53/121 (43%), Gaps = 17/121 (14%)

Query: 31   EQEEPLTDAERMKL-LQEENEELRRRLASATRRTEALERELEIGQDCLELELG------- 82
            E E+ L   ER +  LQ  N  L R++     + +     L   +D L L L        
Sbjct: 1157 ELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVE 1216

Query: 83   QSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLL 142
            ++ EE+D+ +   ++LQ         N+ L+ +L+++ K         D  + +L +K+L
Sbjct: 1217 EAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKK---------DLRLKKLPSKVL 1267

Query: 143  D 143
            D
Sbjct: 1268 D 1268



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 17/153 (11%)

Query: 17   EHRELRLEIPGSRLEQEEPLTDA----ERMKLLQEENEELRRRLASATRRTEALERELEI 72
            E  E++ ++    LE E+    A    + M+L++EE  + +R    A  + + LE+ L+ 
Sbjct: 985  ELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKD 1044

Query: 73   GQDCLELE--LGQSREELDK-FKDKFRRLQ--------NSYTASQRTNQELE--DKLHTL 119
             +  LE +  L   R  L K  +DK  +L+        NS   S+R ++  E  ++L   
Sbjct: 1045 LEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNE 1104

Query: 120  IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLE 152
            + +    R+ L+ + + L  +  D K+ I  LE
Sbjct: 1105 LLQERAARQDLECDKISLERQNKDLKSRIIHLE 1137



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 29/142 (20%), Positives = 60/142 (42%), Gaps = 31/142 (21%)

Query: 38  DAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKF-- 95
           D + + + +EE E+L R+           EREL   +  L+ E+    +E+DK K+++  
Sbjct: 738 DLQDLLIAKEEQEDLLRKR----------ERELTALKGALKEEVSSHDQEMDKLKEQYDA 787

Query: 96  ----------RRLQNSYTASQRTNQELEDKLHTLIK---------KAEMDRKTLDWEIVE 136
                        +N    + R+N   +D+  T ++         K +   + L+  + +
Sbjct: 788 ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQ 847

Query: 137 LTNKLLDAKNTINKLEELNERY 158
           L  ++ D K    K +E  ++Y
Sbjct: 848 LQRQIEDLKGDEAKAKETLKKY 869


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 65/247 (26%), Positives = 86/247 (34%), Gaps = 59/247 (23%)

Query: 193 RKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLL-NSAQSGSAGRPLAEDVF 251
           ++ +  G+    PG   S AP   +P   I+  L  P S  L N++++  A R       
Sbjct: 114 QRDVAGGKTGQGPG---SRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP--- 167

Query: 252 VHVDMSEGVPGDPA-SPPAPGSPTPQPNGECHSLGTARGSPEEEL----------PLPAF 300
                   VP  P  +PP P  P P P      + T   SP   L          P+P  
Sbjct: 168 -----RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC- 221

Query: 301 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSP------------LPNCTYATRQAI 348
               P P P PP P  P         DK   P+ +P            LP C Y   +A 
Sbjct: 222 ---APPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAE 278

Query: 349 SLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAF 408
             S  ++  E   P+P P  P  A  SP       PL    P  ++SSE           
Sbjct: 279 PASPAQDAQE--PPAPPPPLPPYASCSPRASLPAPPL----PGVNSSSE----------- 321

Query: 409 VDRTPPP 415
              TPPP
Sbjct: 322 ---TPPP 325



 Score = 36.6 bits (83), Expect = 0.061
 Identities = 83/381 (21%), Positives = 118/381 (30%), Gaps = 94/381 (24%)

Query: 204 SPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLA---EDVFVHVDMSEGV 260
           +P P P  AP     TS + R   K  S LL   Q G+  R +    +     ++ S+G 
Sbjct: 20  APPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGT 79

Query: 261 PGD---------PASPP------APGSPTPQPNGECHSLGTARG------SPEEELP--- 296
             +          ++PP      A G P  +P G+    G   G      +P   LP   
Sbjct: 80  NKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKT 139

Query: 297 ------LPAFEKLN---------------------PYPTPSPPHPLYPGRRVIEFSEDKV 329
                  PA  +L                      P PTP PP P  P            
Sbjct: 140 ISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLP-----------P 188

Query: 330 RIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSA 389
            +P +SP+     +    ++     +G+      PVP  P      P   P P P     
Sbjct: 189 PLPSSSPIKTPLVSPPGPLT-----KGNLPVVAPPVPCAP------PPPPPPPPPTPPPL 237

Query: 390 PASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQA 449
           P +S  S++ +        +   PPP  +     +     P L+   A    D  E    
Sbjct: 238 PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY-----PGLKAEPASPAQDAQEPPAP 292

Query: 450 PSARPE----ESELLLPTEPDSGFPREEEELNLPISPEEERQSLLPINRGTEEGPGTSHT 505
           P   P          LP  P  G      E   P+ P+       P   G +  P     
Sbjct: 293 PPPLPPYASCSPRASLPAPPLPGV-NSSSETPPPLPPKSPSFQAPPQKAGAQALP----- 346

Query: 506 EGRAWPLPSSSRPQRSPKRMG 526
              A P P  S+P    KR G
Sbjct: 347 ---APPAPPGSQPFLQKKRHG 364


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 69/282 (24%), Positives = 96/282 (34%), Gaps = 33/282 (11%)

Query: 257 SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLY 316
           S  VPG P  P    +P P P     +LG   G    + PL +    +P+    PP P  
Sbjct: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALG---GGSIRQSPLSSS---SPFSN-RPPLPPT 255

Query: 317 PGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTP---ASAQ 373
           P R +    +DK       P P      R +I    V     +    PVPSTP   AS+Q
Sbjct: 256 PSRAL----DDK------PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ 305

Query: 374 ASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQ 433
           A P   P   P     P SS+ ++E   +  +   +  + PP     R+        E  
Sbjct: 306 APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365

Query: 434 RHFAHSPADRDEVVQAPS--ARPEESELLLPTEPD----SGFPREEEELNLPISPEEERQ 487
                 P  R   +  P   +R   +   LP  P     SG          P+ P+    
Sbjct: 366 PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425

Query: 488 SLLP-------INRGTEEGPGTSHTEGRAWPLPSSSRPQRSP 522
              P       I  G ++ P     E R +  P S  P   P
Sbjct: 426 GAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 54/197 (27%), Positives = 69/197 (35%), Gaps = 45/197 (22%)

Query: 362 PSPVPSTPASAQASPHH-----------QPSPAPLTLSAP-------------------A 391
           P PVPSTP   Q+SPH+           QPSP P     P                   +
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243

Query: 392 SSASSEEDLLVSWQRAFVDR-TPPPAAVAQRTAFGRDAL----PELQRHFAHSPADRDEV 446
           S  S+   L  +  RA  D+  PPP  V  R +  R+A+    P+  +    S       
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303

Query: 447 VQAPSARPEESELLLPTEPDSGFPREE----EELNLPIS------PEEERQSLLPINRGT 496
            QAP   P  S    P  P S    +E     + NL +S      P   R   LP     
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363

Query: 497 EEGPGTSHTEGRAWPLP 513
              P      GR+ PLP
Sbjct: 364 RPPPPVRDPPGRSGPLP 380



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 60/227 (26%), Positives = 75/227 (33%), Gaps = 53/227 (23%)

Query: 258 EGVPGDPAS---PPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLN---------- 304
           E VP  P     PP P +P P  + +          P    PLP     N          
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQRN 338

Query: 305 --------PYPTPSPPHPLYPGRRVIEFSEDKVRIP--RNSPLP------------NCTY 342
                   P P+P    PL P     E     VR P  R+ PLP                
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPS--ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396

Query: 343 ATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLV 402
           AT Q  S S V+      RP P+P    SA A     P P P T        S  ED   
Sbjct: 397 ATPQLPSRSGVDSPRSGPRP-PLPPDRPSAGA----PPPPPPSTSIRNGFQDSPCED--- 448

Query: 403 SWQRAF----VDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDE 445
            W+  F    +   PPP    Q T   +    +L R+ + S ++R E
Sbjct: 449 EWESRFYFHPISDLPPPEPYVQTT---KSYPSKLARNESRSGSNRRE 492


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 69/282 (24%), Positives = 96/282 (34%), Gaps = 33/282 (11%)

Query: 257 SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLY 316
           S  VPG P  P    +P P P     +LG   G    + PL +    +P+    PP P  
Sbjct: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALG---GGSIRQSPLSSS---SPFSN-RPPLPPT 255

Query: 317 PGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTP---ASAQ 373
           P R +    +DK       P P      R +I    V     +    PVPSTP   AS+Q
Sbjct: 256 PSRAL----DDK------PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ 305

Query: 374 ASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQ 433
           A P   P   P     P SS+ ++E   +  +   +  + PP     R+        E  
Sbjct: 306 APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365

Query: 434 RHFAHSPADRDEVVQAPS--ARPEESELLLPTEPD----SGFPREEEELNLPISPEEERQ 487
                 P  R   +  P   +R   +   LP  P     SG          P+ P+    
Sbjct: 366 PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425

Query: 488 SLLP-------INRGTEEGPGTSHTEGRAWPLPSSSRPQRSP 522
              P       I  G ++ P     E R +  P S  P   P
Sbjct: 426 GAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 54/197 (27%), Positives = 69/197 (35%), Gaps = 45/197 (22%)

Query: 362 PSPVPSTPASAQASPHH-----------QPSPAPLTLSAP-------------------A 391
           P PVPSTP   Q+SPH+           QPSP P     P                   +
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243

Query: 392 SSASSEEDLLVSWQRAFVDR-TPPPAAVAQRTAFGRDAL----PELQRHFAHSPADRDEV 446
           S  S+   L  +  RA  D+  PPP  V  R +  R+A+    P+  +    S       
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303

Query: 447 VQAPSARPEESELLLPTEPDSGFPREE----EELNLPIS------PEEERQSLLPINRGT 496
            QAP   P  S    P  P S    +E     + NL +S      P   R   LP     
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363

Query: 497 EEGPGTSHTEGRAWPLP 513
              P      GR+ PLP
Sbjct: 364 RPPPPVRDPPGRSGPLP 380



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 60/227 (26%), Positives = 75/227 (33%), Gaps = 53/227 (23%)

Query: 258 EGVPGDPAS---PPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLN---------- 304
           E VP  P     PP P +P P  + +          P    PLP     N          
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQRN 338

Query: 305 --------PYPTPSPPHPLYPGRRVIEFSEDKVRIP--RNSPLP------------NCTY 342
                   P P+P    PL P     E     VR P  R+ PLP                
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPS--ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396

Query: 343 ATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLV 402
           AT Q  S S V+      RP P+P    SA A     P P P T        S  ED   
Sbjct: 397 ATPQLPSRSGVDSPRSGPRP-PLPPDRPSAGA----PPPPPPSTSIRNGFQDSPCED--- 448

Query: 403 SWQRAF----VDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDE 445
            W+  F    +   PPP    Q T   +    +L R+ + S ++R E
Sbjct: 449 EWESRFYFHPISDLPPPEPYVQTT---KSYPSKLARNESRSGSNRRE 492


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 81/338 (23%), Positives = 114/338 (33%), Gaps = 67/338 (19%)

Query: 202  AASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVP 261
            A+SP P P+ +P A   +S ++  L     + + +     A  PL   +   + +S   P
Sbjct: 1411 ASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGP 1470

Query: 262  G---------DPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPP 312
                       P  P APG P+  P+G   S           L L     L+   TP   
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALT------LGLATAPSLSSSQTPG-- 1522

Query: 313  HPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASA 372
            HPL             +  P +S +P        A S  LV      A  SP PS P   
Sbjct: 1523 HPL-------------LLAPTSSHVPGLNSTVAPACSPVLVPAS---ALASPFPSAP--- 1563

Query: 373  QASPHHQPSPAPLTLSAPASSASSEEDL----LVSWQRAFVDRTP-PPAAVAQRTAFGRD 427
                   P+PA  +L APASSAS         + + Q A +  +P PP A     A    
Sbjct: 1564 ------NPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPG 1617

Query: 428  ALPELQRH------FAHSPADRDEVVQA-------PSARPEESELLLPTEPDSGFPREEE 474
            A P L          A S      +  A       P   P  ++ +LP    S  P    
Sbjct: 1618 AAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPAS 1677

Query: 475  ELNLPISPE-------EERQSLLPINRGTEEGPGTSHT 505
               L ++P              L +  G  +GP  + T
Sbjct: 1678 TQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQT 1715



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 10/83 (12%)

Query: 204  SPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVP-- 261
            SP P P+L P A    ++     + P S   +   S S   PL   +   + +S+  P  
Sbjct: 1791 SPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDT 1850

Query: 262  ----GDPASPPAP----GSPTPQ 276
                  P SPP+     G P P+
Sbjct: 1851 LTLRSGPPSPPSTATSFGGPRPR 1873



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 52/197 (26%)

Query: 201  EAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGV 260
            +A +P P P+  P +V+P+S  +     P  L L  A +      +     V + + +  
Sbjct: 1261 QAVAPTPGPT--PVSVLPSSTPSTT-PAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQA- 1316

Query: 261  PGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRR 320
            P D  +P  P +P P+P             P   LP      LNP PT      L PGR 
Sbjct: 1317 PRDGLTPVPPLAPAPRP-------------PSSGLPAV----LNPRPT------LTPGR- 1352

Query: 321  VIEFSEDKVRIPRNSPLPNCTYATRQA-ISLSLVEEGSERARPSPVPSTPASAQASPHHQ 379
                            LP  T  T +A +    +     +   SP P   ASA       
Sbjct: 1353 ----------------LPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASA------- 1389

Query: 380  PSPAPLTLSAPASSASS 396
            P  APLT+S+P    SS
Sbjct: 1390 PGAAPLTISSPLHVPSS 1406



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 52/182 (28%), Positives = 74/182 (40%), Gaps = 27/182 (14%)

Query: 314  PLYPGRRVIEF---SEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA-RPSPVPS-T 368
            P  PG RV E    +  + +   ++P+ +  + TR   +        ER  RP+P P  T
Sbjct: 2388 PERPGTRVSERLRGARAETQGANHTPVISA-HQTRSTTTPPRCSPARERVPRPAPRPRPT 2446

Query: 369  PASAQAS-PHHQPSP--APLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFG 425
            PASA A+ P   P P  AP+ +SAP         +L S         PPP+ +   ++  
Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPS--------PPPPSQIPPCSSPA 2498

Query: 426  RDALPELQRHFAHSPADRDEVVQAPSARPEESELLL--PTEPDSGFPREEEELNLPISPE 483
                P      AH+P      +  PS     S LLL  P+ P S        L L + PE
Sbjct: 2499 CTPPPACTPPPAHTPPPAQTCLVTPS-----SPLLLGPPSVPISA---SVTNLPLGLRPE 2550

Query: 484  EE 485
             E
Sbjct: 2551 AE 2552


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 82/336 (24%), Positives = 123/336 (36%), Gaps = 55/336 (16%)

Query: 203 ASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPG 262
           ASP  +PS  P +  P S+ A  L+ P S   +   S SA  P      +     +    
Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515

Query: 263 DPASPPAPGSPTPQ--PNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRR 320
            P +PPA  +P  Q  P+      G A  SP   LP      ++P  TP P  P      
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP------MSPLATPPPQAPPVLAAP 569

Query: 321 VIEF-----SEDKVRIPRNSPLPN-CTYATRQAISLSLVEEGSERARPSPVPSTPASAQA 374
           +++      +   ++ PR  P P   T  +   ++L+L         P P   +P+S  +
Sbjct: 570 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSPSSTLS 624

Query: 375 SPHHQPSPAPLTLSAPASSASSEEDLLVSWQ---RAFVDRTPPP---AAVAQRTAFGRDA 428
            P          L+  +SSA+S  + L  +          +PPP    A     A+ R  
Sbjct: 625 GP---------DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675

Query: 429 LPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQS 488
            P L   F  +P        AP          LP  P +G P   + L   I   E  +S
Sbjct: 676 APPLA--FRGAPG-------AP----------LPWPPATG-PGSADGL-CTIYETEGPES 714

Query: 489 LLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKR 524
             P     + GP    + G+A     +    RSPK+
Sbjct: 715 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 750



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 76/307 (24%), Positives = 106/307 (34%), Gaps = 55/307 (17%)

Query: 191 MVRKHLHSGQEAASPGPAPSLAP--------GAVVPTSVIARVLEKPESLLLNSAQSG-- 240
           M R+   +G E   P PAPS  P         +V   S  +     P +    SA  G  
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235

Query: 241 -SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPT-PQPNGECHSLGTARGSPEEELPLP 298
             A R L+         +   P    +P AP  P+ P+P G   +L   + +P  +   P
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG-LQALRPPQVTPPRKDAAP 294

Query: 299 AFEKL--NPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEG 356
           A   L  +P  TPSP   L                   S  P    AT  + SL+     
Sbjct: 295 ALGPLSSSPLATPSPSAAL------------------QSQAPPTLPATPHSSSLTC---- 332

Query: 357 SERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTP-PP 415
                 +P+P  P S  A P  Q  P+P   + P+ + +S     +    +F+   P  P
Sbjct: 333 ---QLATPLPLAPPSPSAPPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFLPSPPLSP 388

Query: 416 AAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEE 475
            A     A    ALP LQ               +P A P  S L  P+ P +        
Sbjct: 389 LATPPPQAPPALALPPLQ------------APPSPPASPPLSPLATPS-PQAPNALAVHL 435

Query: 476 LNLPISP 482
           L  P SP
Sbjct: 436 LQAPFSP 442



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 59/230 (25%), Positives = 86/230 (37%), Gaps = 32/230 (13%)

Query: 204 SPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGD 263
           SPGP  S  PG    T+    + +K   L +++ ++ + G+  A +      +S G   D
Sbjct: 110 SPGPVSS--PGRASGTTRPGPLGQK--GLRISAEETVARGK--ATEAPKRSALSAGARRD 163

Query: 264 PASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIE 323
             S P PG+P+P       + GT  G     LP PA     P   P PP    P + V  
Sbjct: 164 -TSGPTPGTPSPAMARRSRAAGTEVG-----LPRPA-----PSARPRPPTE-GPRKSVSS 211

Query: 324 FSEDKVRIPRNSP--LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPS 381
            SE     P  +    P+     ++  S SL    +  + P+    +      +P H   
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271

Query: 382 PAPLTLSA--------PASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTA 423
           P P  L A        P   A+     L S   A    TP P+A  Q  A
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA----TPSPSAALQSQA 317


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 82/336 (24%), Positives = 123/336 (36%), Gaps = 55/336 (16%)

Query: 203 ASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPG 262
           ASP  +PS  P +  P S+ A  L+ P S   +   S SA  P      +     +    
Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476

Query: 263 DPASPPAPGSPTPQ--PNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRR 320
            P +PPA  +P  Q  P+      G A  SP   LP      ++P  TP P  P      
Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP------MSPLATPPPQAPPVLAAP 530

Query: 321 VIEF-----SEDKVRIPRNSPLPN-CTYATRQAISLSLVEEGSERARPSPVPSTPASAQA 374
           +++      +   ++ PR  P P   T  +   ++L+L         P P   +P+S  +
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSPSSTLS 585

Query: 375 SPHHQPSPAPLTLSAPASSASSEEDLLVSWQ---RAFVDRTPPP---AAVAQRTAFGRDA 428
            P          L+  +SSA+S  + L  +          +PPP    A     A+ R  
Sbjct: 586 GP---------DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 636

Query: 429 LPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQS 488
            P L   F  +P        AP          LP  P +G P   + L   I   E  +S
Sbjct: 637 APPLA--FRGAPG-------AP----------LPWPPATG-PGSADGL-CTIYETEGPES 675

Query: 489 LLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKR 524
             P     + GP    + G+A     +    RSPK+
Sbjct: 676 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 48/188 (25%), Positives = 73/188 (38%), Gaps = 20/188 (10%)

Query: 204 SPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGD 263
           SPGP  S  PG    T+    + +K   L +++ ++ + G+  A +      +S G   D
Sbjct: 101 SPGPVSS--PGRASGTTRPGPLGQK--GLRISAEETVARGK--ATEAPKRSALSAGARRD 154

Query: 264 PASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIE 323
             S P PG+P+P       + GT  G     LP PA     P   P PP    P + V  
Sbjct: 155 -TSGPTPGTPSPAMARRSRAAGTEVG-----LPRPA-----PSARPRPPTE-GPRKSVSS 202

Query: 324 FSEDKVRIPRNSP--LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPS 381
            SE     P  +    P+     ++  S SL    +  + P+    +      +P H   
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262

Query: 382 PAPLTLSA 389
           P P  L A
Sbjct: 263 PKPKGLQA 270



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 70/295 (23%), Positives = 91/295 (30%), Gaps = 61/295 (20%)

Query: 191 MVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDV 250
           M R+   +G E   P PAPS  P    PT    + +              +  RP A   
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224

Query: 251 FVH-VDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLP-AFEKLNPYPT 308
                  S      P S PA   P+ +        GT R       P P   + L P P 
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSAR--------GTPRAPAHPSQPKPKGLQALRP-PQ 275

Query: 309 PSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPST 368
            +PP               K   P   PL +   AT                   P PS 
Sbjct: 276 VTPPR--------------KDAAPALGPLSSSPLAT-------------------PSPSA 302

Query: 369 PASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTP-PPAAVAQRTAFGRD 427
           P S  A P  Q  P+P   + P+ + +S     +    +F+   P  P A     A    
Sbjct: 303 PPSPSAPPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361

Query: 428 ALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISP 482
           ALP LQ               +P A P  S L  P+ P +        L  P SP
Sbjct: 362 ALPPLQ------------APPSPPASPPLSPLATPS-PQAPNALAVHLLQAPFSP 403


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 97/401 (24%), Positives = 138/401 (34%), Gaps = 41/401 (10%)

Query: 12   RKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRTEAL----- 66
            +K P E RE      G  +E+E     +E  K  +E+ +E      S     + +     
Sbjct: 769  KKEPKEPRE-----GGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEK 823

Query: 67   ERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLIKKAEMD 126
            E+E + GQ+ +  E+ +S  E     ++     N  TA+         K   L    E  
Sbjct: 824  EKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERK 883

Query: 127  RKTLDWEIVELTNKLLDAK-NTINKLEELNERYRLDCNLAVQLLKCNKS--HFRNHKFAD 183
             K+L   +VE   K L+ K     +LE + +R R       Q L  ++   H    K+A+
Sbjct: 884  IKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAE 943

Query: 184  LPCELQDMVRKHLHSGQE--AASPGPAPSLAPGA----------VVPTSVIARVLEK--P 229
            +    Q   + H    Q   A  PG  P    GA          V P SV+        P
Sbjct: 944  MRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAP 1003

Query: 230  ESLLLNSAQSGSAGR---PLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGT 286
               L  S Q G AG    P  +            PG P  PP P  P+P PN +      
Sbjct: 1004 PGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVP--PPGPHGPSPFPNQQTPPSMM 1061

Query: 287  ARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQ 346
                P    P  A       P   PP P  P   +I F      I  N P P   +    
Sbjct: 1062 PGAVPGSGHPGVAGNAPLGLPFGMPPPPPPPAPSIIPFGSLADSISINLPAPPNLHGHHH 1121

Query: 347  AISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTL 387
             +  +            P P+ P S  A+P H   PA  T+
Sbjct: 1122 HLPFA--------PGTLPPPNLPVS-MANPLHPNLPATTTM 1153


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 65/243 (26%), Positives = 89/243 (36%), Gaps = 36/243 (14%)

Query: 188 LQDMVRKHLHSGQ--------EAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQS 239
           LQD V   L S +         A +P PAP+ AP A  P    A   E+ ES +     S
Sbjct: 486 LQDTVSDRLASEELPSTAVPTPATTPAPAPAPAP-APAPALASAATKERTESEVPPRPAS 544

Query: 240 GSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPA 299
               R   E      DM+        +P  P  P PQ +G       +R SP    P P 
Sbjct: 545 PKVTRSPPETAAPVEDMARRTKRP--APARPTMPPPQVSG-------SRSSP----PAPP 591

Query: 300 FEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSER 359
                P  + SP  P    RR++  S     +P   P      A RQ          S R
Sbjct: 592 L----PPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQ----------SRR 637

Query: 360 ARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVA 419
           +  SP P++P  A  SP    +PA + L A  +   + E +        +   P P ++A
Sbjct: 638 SPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSLA 697

Query: 420 QRT 422
             T
Sbjct: 698 SET 700


>gi|156104862 ankyrin repeat domain 38 [Homo sapiens]
          Length = 995

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/163 (25%), Positives = 61/163 (37%), Gaps = 26/163 (15%)

Query: 256 MSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPL 315
           +S G P  PA PP  G  +              G+ E    L  F   +P  +   P  +
Sbjct: 180 LSLGPPAPPALPPLQGEGS-----------VCDGTFEPAEGLAGFHSSSPRASTRIPELV 228

Query: 316 YPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQAS 375
             G    E  E  V++P + PLP   ++ +  + +   +E    AR + V  TP S   S
Sbjct: 229 QEGA---EPPEGVVKVPNHLPLPGPPFSFQNVLVVLEDKEDEHNAREAEVLFTPGSPTPS 285

Query: 376 PHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAV 418
           P   PSP P            E +LL+      +   PPP  V
Sbjct: 286 PPPLPSPIP------------ENELLLEEIELNISEIPPPPPV 316



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 87/355 (24%), Positives = 122/355 (34%), Gaps = 51/355 (14%)

Query: 196 LHSGQEAASPG-----PAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDV 250
           LHS + +  PG     PAP   P      SV     E  E L    + S  A   + E V
Sbjct: 170 LHS-RASEEPGLSLGPPAPPALPPLQGEGSVCDGTFEPAEGLAGFHSSSPRASTRIPELV 228

Query: 251 FVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNP-YPTP 309
               +  EGV   P   P PG P    N     L       +E     A     P  PTP
Sbjct: 229 QEGAEPPEGVVKVPNHLPLPGPPFSFQN----VLVVLEDKEDEHNAREAEVLFTPGSPTP 284

Query: 310 SP---PHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVP 366
           SP   P P+     ++E  E ++ I    P P      R +I + + EE    AR  P  
Sbjct: 285 SPPPLPSPIPENELLLE--EIELNISEIPPPPPVEVDMR-SIGIRVTEESLGLARVDPGS 341

Query: 367 STPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGR 426
            +    Q             +SA     S   + L   + A   +     A  QR     
Sbjct: 342 ISSLKQQ-------------VSALEGELSGRTEELAQVRTALQQQEEEIKAREQRIRELE 388

Query: 427 DALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEE-----ELNLPIS 481
             + +L+  F H    +D   Q        +++++ T+P  G    E      E+NL  S
Sbjct: 389 FTVAQLEGQF-HQENAKDTQGQ--------TDVMVNTDPVHGLLTRESCDKGIEVNLLGS 439

Query: 482 PEEERQSLLPINRGTEEGPGTSHTEGRAWP-----LPSSSRPQRSPKRMGVHHLH 531
            E E         G   GP   H +G   P     LP  S PQ  P+++    +H
Sbjct: 440 MESESWGHRGEENGLLWGP-DGHKQGNQSPAERVLLPQLSLPQ-GPEQVLTSSVH 492


>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
          Length = 931

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 43/144 (29%), Positives = 62/144 (43%), Gaps = 22/144 (15%)

Query: 201 EAASPGPAPS--------LAPGAVVPTSVIARV---LEKPESLLLNSAQSGSAGRPLAED 249
           +  SP PAPS        L P    PTS++ +     E+  S      ++GS+ + + +D
Sbjct: 692 QPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQM-DD 750

Query: 250 VFVHVDMSEGVPGDPASPPA-PGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPT 308
           +F  +  S  +  D   PP+ PG   P P   C S   A+ SP  ELP  A         
Sbjct: 751 LFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAA--------P 802

Query: 309 PSPPHPLYPGRRVIEFSEDKVRIP 332
           P P  P  PG R+ +F E    +P
Sbjct: 803 PPPGSPSLPG-RLEDFLESSTGLP 825


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 90/343 (26%), Positives = 117/343 (34%), Gaps = 66/343 (19%)

Query: 198 SGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLL-NSAQSGSAGRPLAEDVFVHVDM 256
           +G     P PA S  PG     S   R    PE  L  +S  S  +G P           
Sbjct: 545 AGAAPCPPNPANSWVPGLSPGGS--RRPPRSPERTLSPSSGYSSQSGTPTLPP------- 595

Query: 257 SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTP-SPPHPL 315
            +G+ G PASP     P P+      SL +   S    L        +P P+  S P  L
Sbjct: 596 -KGLAGPPASPGKAQPPKPE---RVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651

Query: 316 YP-GRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQA 374
            P G R +     KV  P + P          A +L+     +    P PV +T AS Q+
Sbjct: 652 TPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALA-----APAVVPGPVSTTDASPQS 706

Query: 375 SPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQR 434
            P  Q +  PL  S   S                 D++PPP+             P    
Sbjct: 707 PPTPQTTLTPLQESPVISK----------------DQSPPPS-------------PPPSY 737

Query: 435 HFAHSPADRDE-VVQAPSARPEESELL-----------LPTEPD---SGFPREEEELNLP 479
           H    P  + E VV+APSA     E L            P E D   + FP  EE     
Sbjct: 738 HPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSV 797

Query: 480 ISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSP 522
            SPE    S  P    +     +S T  +  P P S  P  +P
Sbjct: 798 ASPEPAGPSGSPELVSSPAASSSSATALQIQP-PGSPDPPPAP 839



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 51/189 (26%), Positives = 70/189 (37%), Gaps = 37/189 (19%)

Query: 261  PGDPASPPAPGSPTPQPNGECH--------SLGTARGS--PEEELPLPAFEKL------- 303
            PG P  PPAP +P P  +   H         +G ++G   P E++  P            
Sbjct: 830  PGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRL 889

Query: 304  --------NPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNS-----PLPNCTYATRQAISL 350
                     P P   P  P  P RR +      V  P +       L  C+ A  + +S 
Sbjct: 890  RSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLS- 948

Query: 351  SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDL---LVSWQRA 407
            S    G   A P P P +PAS  AS         L L  P  S  ++ DL   LV+  R+
Sbjct: 949  SAQPNGPPEAEPRP-PQSPAST-ASFIFSKGSRKLQLERPV-SPETQADLQRNLVAELRS 1005

Query: 408  FVDRTPPPA 416
              ++ PP A
Sbjct: 1006 ISEQRPPQA 1014



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 58/240 (24%), Positives = 87/240 (36%), Gaps = 52/240 (21%)

Query: 186 CELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRP 245
           C L+ + R  LHS    ASP    SL   + V +        +P S   +S+ S +    
Sbjct: 372 CSLRTLSRCSLHS----ASPASVRSLGRFSSVSSP-------QPRSRHPSSS-SDTWSHS 419

Query: 246 LAEDVFVH----VDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFE 301
            + D  V     +    G  G P S  A  S  P P G     G+ RGSP       A +
Sbjct: 420 QSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQG-----GSGRGSPSGGSTAEASD 474

Query: 302 KLN-------------------PYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTY 342
            L+                   P P P   H L+  +R +   +  + +P     P    
Sbjct: 475 TLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLH--QRGLAVPDGPLGLP-----PKPER 527

Query: 343 ATRQAISLSLVEEGSERARPSPVPSTPASAQA---SP--HHQPSPAPLTLSAPASSASSE 397
             +  +       GSE A  +P P  PA++     SP    +P  +P    +P+S  SS+
Sbjct: 528 KQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQ 587


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,307,292
Number of Sequences: 37866
Number of extensions: 1788421
Number of successful extensions: 17125
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 206
Number of HSP's successfully gapped in prelim test: 1310
Number of HSP's that attempted gapping in prelim test: 11443
Number of HSP's gapped (non-prelim): 5708
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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