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Search of human proteins with 225690489
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225690489 tight junction associated protein 1 isoform a
[Homo sapiens]
(557 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225690489 tight junction associated protein 1 isoform a [Homo... 1122 0.0
gi|225690487 tight junction associated protein 1 isoform a [Homo... 1122 0.0
gi|225690497 tight junction associated protein 1 isoform b [Homo... 1093 0.0
gi|225690495 tight junction associated protein 1 isoform b [Homo... 1093 0.0
gi|225690493 tight junction associated protein 1 isoform b [Homo... 1093 0.0
gi|225690491 tight junction associated protein 1 isoform b [Homo... 1093 0.0
gi|227497884 brain-enriched guanylate kinase-associated protein ... 166 5e-41
gi|13124765 brain-enriched guanylate kinase-associated protein [... 166 5e-41
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 2e-06
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 50 4e-06
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 50 4e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 50 4e-06
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 50 5e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 50 7e-06
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ... 49 1e-05
gi|216548091 leucine zipper protein 1 [Homo sapiens] 49 1e-05
gi|216548085 leucine zipper protein 1 [Homo sapiens] 49 1e-05
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 49 2e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 49 2e-05
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 48 2e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 48 3e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 48 3e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 48 3e-05
gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 48 3e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 47 4e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 47 4e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 47 5e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 47 5e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 47 5e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 47 5e-05
>gi|225690489 tight junction associated protein 1 isoform a [Homo
sapiens]
Length = 557
Score = 1122 bits (2901), Expect = 0.0
Identities = 557/557 (100%), Positives = 557/557 (100%)
Query: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
Query: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA
Sbjct: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180
SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
Sbjct: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180
Query: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240
CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
Sbjct: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240
Query: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300
SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
Sbjct: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300
Query: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
Sbjct: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
Query: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420
SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
Sbjct: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420
Query: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP
Sbjct: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
Query: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540
REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
Sbjct: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540
Query: 541 HRKDSLTQAQEQGNLLN 557
HRKDSLTQAQEQGNLLN
Sbjct: 541 HRKDSLTQAQEQGNLLN 557
>gi|225690487 tight junction associated protein 1 isoform a [Homo
sapiens]
Length = 557
Score = 1122 bits (2901), Expect = 0.0
Identities = 557/557 (100%), Positives = 557/557 (100%)
Query: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
Query: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA
Sbjct: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180
SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
Sbjct: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180
Query: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240
CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
Sbjct: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240
Query: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300
SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
Sbjct: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300
Query: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
Sbjct: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
Query: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420
SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
Sbjct: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420
Query: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP
Sbjct: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
Query: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540
REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
Sbjct: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540
Query: 541 HRKDSLTQAQEQGNLLN 557
HRKDSLTQAQEQGNLLN
Sbjct: 541 HRKDSLTQAQEQGNLLN 557
>gi|225690497 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 1093 bits (2827), Expect = 0.0
Identities = 547/557 (98%), Positives = 547/557 (98%), Gaps = 10/557 (1%)
Query: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
Query: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL
Sbjct: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL- 119
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180
IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
Sbjct: 120 ---------IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 170
Query: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240
CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
Sbjct: 171 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 230
Query: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300
SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
Sbjct: 231 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 290
Query: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
Sbjct: 291 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 350
Query: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420
SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
Sbjct: 351 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 410
Query: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP
Sbjct: 411 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 470
Query: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540
REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
Sbjct: 471 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 530
Query: 541 HRKDSLTQAQEQGNLLN 557
HRKDSLTQAQEQGNLLN
Sbjct: 531 HRKDSLTQAQEQGNLLN 547
>gi|225690495 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 1093 bits (2827), Expect = 0.0
Identities = 547/557 (98%), Positives = 547/557 (98%), Gaps = 10/557 (1%)
Query: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
Query: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL
Sbjct: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL- 119
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180
IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
Sbjct: 120 ---------IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 170
Query: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240
CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
Sbjct: 171 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 230
Query: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300
SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
Sbjct: 231 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 290
Query: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
Sbjct: 291 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 350
Query: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420
SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
Sbjct: 351 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 410
Query: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP
Sbjct: 411 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 470
Query: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540
REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
Sbjct: 471 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 530
Query: 541 HRKDSLTQAQEQGNLLN 557
HRKDSLTQAQEQGNLLN
Sbjct: 531 HRKDSLTQAQEQGNLLN 547
>gi|225690493 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 1093 bits (2827), Expect = 0.0
Identities = 547/557 (98%), Positives = 547/557 (98%), Gaps = 10/557 (1%)
Query: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
Query: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL
Sbjct: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL- 119
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180
IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
Sbjct: 120 ---------IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 170
Query: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240
CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
Sbjct: 171 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 230
Query: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300
SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
Sbjct: 231 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 290
Query: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
Sbjct: 291 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 350
Query: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420
SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
Sbjct: 351 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 410
Query: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP
Sbjct: 411 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 470
Query: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540
REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
Sbjct: 471 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 530
Query: 541 HRKDSLTQAQEQGNLLN 557
HRKDSLTQAQEQGNLLN
Sbjct: 531 HRKDSLTQAQEQGNLLN 547
>gi|225690491 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 1093 bits (2827), Expect = 0.0
Identities = 547/557 (98%), Positives = 547/557 (98%), Gaps = 10/557 (1%)
Query: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
Sbjct: 1 MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT 60
Query: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL
Sbjct: 61 RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL- 119
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 180
IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
Sbjct: 120 ---------IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK 170
Query: 181 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 240
CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
Sbjct: 171 CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE 230
Query: 241 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 300
SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
Sbjct: 231 SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS 290
Query: 301 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
Sbjct: 291 PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL 350
Query: 361 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 420
SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
Sbjct: 351 SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD 410
Query: 421 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP
Sbjct: 411 RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 470
Query: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 540
REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
Sbjct: 471 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL 530
Query: 541 HRKDSLTQAQEQGNLLN 557
HRKDSLTQAQEQGNLLN
Sbjct: 531 HRKDSLTQAQEQGNLLN 547
>gi|227497884 brain-enriched guanylate kinase-associated protein
[Homo sapiens]
Length = 593
Score = 166 bits (420), Expect = 5e-41
Identities = 106/264 (40%), Positives = 151/264 (57%), Gaps = 27/264 (10%)
Query: 40 ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99
E++ LQE+ ELR+RL+ T + E LE E + + LE+EL +++EEL+K +K RR+Q
Sbjct: 2 EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
Query: 100 NSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTIN 159
++Y A QR NQELEDKL+ + + E +++ L EIV L + LL+AK TI+
Sbjct: 62 SNYMALQRINQELEDKLYRMG----------QHYEEEKRALSHEIVALNSHLLEAKVTID 111
Query: 160 KLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAP 219
KL E NE YR DCNLA QLL+C++++ R HK ++LP + Q+ V H+ + P P
Sbjct: 112 KLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLC 170
Query: 220 SLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPA 279
A VPT VIA+VLEKP+ L+S S ++ R LA +GV
Sbjct: 171 HPAYADSVPTCVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EK 215
Query: 280 PGSPTPQPNGECHSLGTARGSPEE 303
PG P P G+ + TA PEE
Sbjct: 216 PG-PRPPYKGDIYCSDTALYCPEE 238
>gi|13124765 brain-enriched guanylate kinase-associated protein
[Homo sapiens]
Length = 593
Score = 166 bits (420), Expect = 5e-41
Identities = 106/264 (40%), Positives = 151/264 (57%), Gaps = 27/264 (10%)
Query: 40 ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99
E++ LQE+ ELR+RL+ T + E LE E + + LE+EL +++EEL+K +K RR+Q
Sbjct: 2 EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
Query: 100 NSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTIN 159
++Y A QR NQELEDKL+ + + E +++ L EIV L + LL+AK TI+
Sbjct: 62 SNYMALQRINQELEDKLYRMG----------QHYEEEKRALSHEIVALNSHLLEAKVTID 111
Query: 160 KLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAP 219
KL E NE YR DCNLA QLL+C++++ R HK ++LP + Q+ V H+ + P P
Sbjct: 112 KLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLC 170
Query: 220 SLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPA 279
A VPT VIA+VLEKP+ L+S S ++ R LA +GV
Sbjct: 171 HPAYADSVPTCVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EK 215
Query: 280 PGSPTPQPNGECHSLGTARGSPEE 303
PG P P G+ + TA PEE
Sbjct: 216 PG-PRPPYKGDIYCSDTALYCPEE 238
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 51.6 bits (122), Expect = 2e-06
Identities = 83/356 (23%), Positives = 122/356 (34%), Gaps = 51/356 (14%)
Query: 213 ASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPG 272
ASP +PS P + P S+ A L+ P S + S SA P + + P
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 273 DPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVI 332
PASPP S TP P PL A L P+P P+ P +
Sbjct: 741 PPASPPMSPSATPPPRVP---------------PLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 333 EFSEDKVRIP--RNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQP 390
+ + P + P P ++ + S S S A P P +A
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845
Query: 391 SPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSP 450
PA TL AP + D VS R + P P R+ + P+L H + +
Sbjct: 846 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 905
Query: 451 ADRDEV--------VQAPSARPEESELL------------------------LPTEPDSG 478
+ +E+ A ++ P ++EL LP P +G
Sbjct: 906 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 965
Query: 479 FPREEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKR 534
P + L I E +S P + GP + G+A + RSPK+
Sbjct: 966 -PGSADGL-CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019
Score = 45.8 bits (107), Expect = 1e-04
Identities = 90/372 (24%), Positives = 124/372 (33%), Gaps = 60/372 (16%)
Query: 201 MVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDV 260
M R+ +G E P PAPS P PT + + + RP A
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSA--- 230
Query: 261 FVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPS 320
G PAS S TP + S +ARG+P +
Sbjct: 231 -------GGGLQRPASRSLSSSATPL-SSPARSGPSARGTPR-----------------A 265
Query: 321 PPHPLYPGRRVIE-FSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTP 379
P HP P + ++ +V PR P + L+ +ARP P P
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLATPSPSGTKARPVPPPDNA 323
Query: 380 ASAQAS--PHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRD 437
A+ + P P PL L+ P+ SA L S TPP A T
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS-----PPATPPSQAPPSMTTPPMQ 378
Query: 438 ALPELQR-------HFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPI 490
A P LQ H SP+ +QAP + S L T S + L +
Sbjct: 379 APPSLQTIPPIQVPHSLTSPS-----LQAPPSPLALSSLQATTSLGSPTLQATHSF-LTM 432
Query: 491 SPEEERQSLLPINRGTEEGPGTSHTEG-----RAWPLPSSSRPQRSP--KRMGVHHLHRK 543
SP + + SL +R P + + + PL +S P SP + +H L
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
Query: 544 DSLTQAQEQGNL 555
SL Q L
Sbjct: 493 SSLASHSPQAPL 504
Score = 42.4 bits (98), Expect = 0.001
Identities = 79/323 (24%), Positives = 114/323 (35%), Gaps = 37/323 (11%)
Query: 220 SLAPGAVV--PTSVIARVLEKPESLLLNSAQSGSAG--RPLAEDVFVHVDMSEGVPGDPA 275
SLAP ++ P S+ LE SL Q+ SA P E P P
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL 576
Query: 276 SPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFS 335
+ P P +P+ + P + LP P L+P TP P P ++
Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSPP---LSPLATPPPQAPPXLALPPLQAP 633
Query: 336 EDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPL 395
P SPL + A+++ L++ PSP P S ASP PS P
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPP 692
Query: 396 TLSAPASSASSEEDLLVSWQRAFVDRTPP------PAAVAQRTAFGRDALPELQRHFAHS 449
+ + P+ +A + V +PP P+A A A P LQ
Sbjct: 693 SQAPPSLAAPPLQ----------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQ----VP 738
Query: 450 PADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQSLLPINRGTEEG 509
P+ +PSA P L P P +LP+SP + P
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLPMSPLAKPPPQAP-------- 789
Query: 510 PGTSHTEGRAWPLPSSSRPQRSP 532
P + +A P P +S P ++P
Sbjct: 790 PALATPPLQALPSPPASFPGQAP 812
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 50.4 bits (119), Expect = 4e-06
Identities = 71/256 (27%), Positives = 98/256 (38%), Gaps = 49/256 (19%)
Query: 254 RPLAEDVFVHVDMSEG-VPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEK 312
R +AE++ + E +P P +PPAP P P P SP L P
Sbjct: 384 RAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLP--------PPSTSPPPPLCPPPPPP 435
Query: 313 LNPYPTPSPPHPLYPGRRVIEFSEDKV------RIPRNSPLPNCTYATRQAISLSLVEEG 366
++P P PSPP P P + E S V R PL A R+A EG
Sbjct: 436 VSPPPLPSPPPP--PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAG--PEG 491
Query: 367 SERARPSPVPSTPASAQASPHHQPSPAPLTLS---------APASSASSEEDLLVSWQRA 417
+ + P+P PST + P P+ AP + + P SA S ++ R
Sbjct: 492 T--SPPTPTPST--ATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSR--VIKTPRR 545
Query: 418 FVDRTPP-PAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPD 476
F+D PP P V + P L+ SP V Q P+ P S PT P
Sbjct: 546 FMDEDPPKPPKV--------EVSPVLRPPITTSP----PVPQEPA--PVPSPPRAPTPPS 591
Query: 477 SGFPREEEELNLPISP 492
+ P E+ ++ P
Sbjct: 592 TPVPLPEKRRSILREP 607
Score = 43.5 bits (101), Expect = 5e-04
Identities = 57/216 (26%), Positives = 77/216 (35%), Gaps = 41/216 (18%)
Query: 215 PGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDP 274
P P PS P A P S + EK S+L E F ++ +P P
Sbjct: 577 PAPVPS-PPRAPTPPSTPVPLPEKRRSIL-------------REPTFRWTSLTRELPPPP 622
Query: 275 ASPPAPGSPTPQPNGECHS----LGTARGSPEEELPLPAFEK-LNPYPTPSPPHPLYPGR 329
+PP P +P+P P S L A E L +E L P P +P P
Sbjct: 623 PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP----- 677
Query: 330 RVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQ 389
E + +SP A + LSL R +PV +TP A+ SPH
Sbjct: 678 ------EPEPPPADDSPAEPEPRAVGRTNHLSL-------PRFAPVVTTPVKAEVSPH-- 722
Query: 390 PSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPP 425
AP + P + A + L + PPP
Sbjct: 723 --GAPALSNGPQTQAQLLQPLQALQTQLLPQALPPP 756
Score = 40.8 bits (94), Expect = 0.003
Identities = 53/235 (22%), Positives = 82/235 (34%), Gaps = 31/235 (13%)
Query: 270 VPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGR 329
VP P +P P +P P P L E + + P P P+PP P
Sbjct: 580 VPSPPRAPTPPSTPVPLPEKRRSILR------EPTFRWTSLTRELPPPPPAPPPP----- 628
Query: 330 RVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVE----EGSERARPSPVPSTPASAQAS 385
P SP P ++R+ + L + E + S + P A +
Sbjct: 629 ------------PAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEA 676
Query: 386 PHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRH 445
P +P PA + + P A + L + A V TP A V+ A P+ Q
Sbjct: 677 PEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQ 736
Query: 446 FAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEEL----NLPISPEEER 496
+ + P + +L P P P E+ + +LP+S EE+
Sbjct: 737 LLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEK 791
Score = 35.4 bits (80), Expect = 0.14
Identities = 93/394 (23%), Positives = 132/394 (33%), Gaps = 91/394 (23%)
Query: 213 ASPGPAPSLAPGAV---------VPTSVIARVLEKPESL--------LLNSAQSGSAG-- 253
++PG APS PGA T A +++P ++ + G+AG
Sbjct: 2043 SAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDR 2102
Query: 254 -RP---LAEDVFVHVDMSEGVPGDPASPPAPGSPTPQP---NGECHSLGTARGSPEEE-- 304
RP L ++ V + G PGD + P S P P NG S G SP +
Sbjct: 2103 ARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLT-ASPADPTR 2161
Query: 305 ----LP-LPAFEKLNPYPTPSPPHPLYP--------GRRVIEFSEDKVRIP---RNSPLP 348
LP P L+ P P PP P G+ ++ + + +P + PLP
Sbjct: 2162 TFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLP 2221
Query: 349 NCTYATRQAISLSLVEEGSERARPSPVPST-PASAQASPHHQPSPAPLTLSAPASSAS-S 406
++S S P P+ P P P P PLTL + AS
Sbjct: 2222 P---------TISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPP 2272
Query: 407 EEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEE 466
+ + V F R+PP + D + D +V S
Sbjct: 2273 RQAIRVKRVSTFSGRSPPAPPPYKAPRLDED---------GEASEDTPQVPGLGSGGFSR 2323
Query: 467 SELLLPTEP---DSGFPREEEELNLPISPEEERQSLLPINRGTEEGPGT----------- 512
+ PT D P E P P +ER LLP+ E+GP
Sbjct: 2324 VRMKTPTVRGVLDLDRPGEPAGEESP-GPLQERSPLLPL---PEDGPPQVPDGPPDLLLE 2379
Query: 513 ---SHTEGRA-----WPLPSSSRPQRSPKRMGVH 538
H G A P + ++PKR G H
Sbjct: 2380 SQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPH 2413
Score = 32.7 bits (73), Expect = 0.90
Identities = 52/224 (23%), Positives = 74/224 (33%), Gaps = 46/224 (20%)
Query: 275 ASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEK----------LNPYPTPSPPHP 324
A P PTP P+ TA G P E+ P A + + P +
Sbjct: 487 AGPEGTSPPTPTPS-------TATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRV 539
Query: 325 LYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQA 384
+ RR ++ ED + P+ P R I+ S PVP PA
Sbjct: 540 IKTPRRFMD--EDPPKPPKVEVSP----VLRPPITTS-----------PPVPQEPAPVP- 581
Query: 385 SPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQR 444
SP P+P + P S + W + PPP A A P
Sbjct: 582 SPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA--- 638
Query: 445 HFAHSPADRDEVVQAPSARPEESELLL----PTEPDSGFPREEE 484
+ + R +++AP P E+ L + T P G P E
Sbjct: 639 ----TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPE 678
Score = 32.3 bits (72), Expect = 1.2
Identities = 40/124 (32%), Positives = 51/124 (41%), Gaps = 25/124 (20%)
Query: 213 ASPGP-APSLAPGAVVPTS-VIARV-LEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEG 269
ASPGP P GA P V+A E+ +SLL + + + D+F D SE
Sbjct: 1038 ASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSE- 1096
Query: 270 VPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLN--PYPTPSPPHPLYP 327
P PPAP TP+ E ELPLP E+ + PT P L
Sbjct: 1097 ----PGGPPAPRRRTPR---------------ENELPLPEPEEQSRPRKPTLQPVLQLKA 1137
Query: 328 GRRV 331
RR+
Sbjct: 1138 RRRL 1141
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 50.4 bits (119), Expect = 4e-06
Identities = 91/363 (25%), Positives = 131/363 (36%), Gaps = 55/363 (15%)
Query: 215 PGPAPSLAPGAV--VPTSVIARVLEKPESLLLNSAQSGSAGR-------------PLAED 259
P P S PG V P + R +P L ++ Q GS G PL
Sbjct: 891 PLPPASNPPGTVHSAPNRGLGR---RPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTS 947
Query: 260 VFVHVDM----SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNP 315
++ S+ VP A+PP P +PQ G S+ + GSP L P+ +P
Sbjct: 948 PSANLKSPQTPSQMVPLPSANPPGP-LKSPQVLGSSLSVRSPTGSPSR-LKSPSMAVPSP 1005
Query: 316 YPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYAT------RQAISLSLVEEGSER 369
SP + P V + + + + ++ L N T R + S S
Sbjct: 1006 GWVASPKTAM-PSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGL 1064
Query: 370 ARPS--------PVPS-TPAS---AQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRA 417
PS P PS P S Q S + PS PL +A + A+S+++LL R
Sbjct: 1065 MNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLP--DRP 1122
Query: 418 FVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAP-SARPEESELLLPTEPD 476
+ PPP + + + L A SP + Q P S P + L PT
Sbjct: 1123 LLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLG 1182
Query: 477 SGFPREEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMG 536
S N+P+ P + P N G P+PSSS+ P R+
Sbjct: 1183 S---------NIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQ 1233
Query: 537 VHH 539
H
Sbjct: 1234 QPH 1236
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 50.4 bits (119), Expect = 4e-06
Identities = 73/281 (25%), Positives = 101/281 (35%), Gaps = 54/281 (19%)
Query: 274 PASPPAPG-SPTPQPNGECHSLGTARGSPEEELPLPAFEK-LNPYPTP-----SPPHPLY 326
PA PP +PTP P S R SP P ++ +P P P SPP P
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP-- 620
Query: 327 PGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASP 386
P RR K R+ + P + + S SL + + + PS S Q +
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK 680
Query: 387 HHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHF 446
H PSP P AP +S+S PPP R A QR
Sbjct: 681 RHSPSPRP---RAPQTSSS-----------------PPPVR--------RGASSSPQRRQ 712
Query: 447 AHSPADR-----------DEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEE 495
+ SP+ R ++ +A S P+ + + SG P E P +P
Sbjct: 713 SPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSP--EPAAKKPPAPPSP 770
Query: 496 RQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMG 536
QS P T P + ++ P PS S P+ S + G
Sbjct: 771 VQSQSP---STNWSPAVPVKKAKS-PTPSPSPPRNSDQEGG 807
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 50.1 bits (118), Expect = 5e-06
Identities = 89/339 (26%), Positives = 125/339 (36%), Gaps = 63/339 (18%)
Query: 208 SGQEAASPGPAPSLAPGAVV---PTSVIARVLEKPESLLLNSAQSGSAGRPLAEDV--FV 262
S +E A ++A +V P + A ++E P + SA+ + LAE +
Sbjct: 296 STEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSA 355
Query: 263 HVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPP 322
SE P + PPA SP+ + GE S +A+ +P E PLPA L P P
Sbjct: 356 EESPSEEPPAEILPPPAEKSPSVELLGEIRS-PSAQKAPIEVQPLPAEGALEEAPAKVEP 414
Query: 323 ----------HPLYPGR------------RVIEFSEDKVRIPRNSPLPNCTYATRQAISL 360
PL P +E ++ SPLP T A + +
Sbjct: 415 PTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEI 474
Query: 361 SLVEEGSERARPSPVPSTPASAQ--------ASPHHQPSPAPLTLSAPASSASSEEDLLV 412
L+ A P TPA A+ A H +PL A AS+E LL
Sbjct: 475 QLL-----AATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLA 529
Query: 413 SWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEE-SELLL 471
+ + A D TP A + L E + +PA+ VQ+PSA+ E L
Sbjct: 530 AIE-APADETPAEA---------QSPLSE-ETSAEEAPAE----VQSPSAKGVSIEEAPL 574
Query: 472 PTEPDSGFPREEEELNLPISPEEERQSLLPINRGTEEGP 510
+P SG EE + I Q L EE P
Sbjct: 575 ELQPPSGEETTAEEASAAI------QLLAATEASAEEAP 607
Score = 37.0 bits (84), Expect = 0.048
Identities = 45/175 (25%), Positives = 59/175 (33%), Gaps = 36/175 (20%)
Query: 362 LVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDR 421
LVEE + +A P P T Q S P A A++A +E + V
Sbjct: 273 LVEEATAKAEPRPAEETHVQVQPSTEETP-------DAEAATAVAENSVKVQ-------- 317
Query: 422 TPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEES-ELLLPTEPDSGFP 480
PPPA A F PA+ +Q PSA S ELL P S
Sbjct: 318 -PPPAEEAPLVEF---------------PAE----IQPPSAEESPSVELLAEILPPSAEE 357
Query: 481 REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRM 535
EE I P +S G P PLP+ + +P ++
Sbjct: 358 SPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKV 412
Score = 33.1 bits (74), Expect = 0.69
Identities = 58/240 (24%), Positives = 87/240 (36%), Gaps = 49/240 (20%)
Query: 211 EAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGV 270
E SP + A A ++A + E P AQS PL+E+ +E
Sbjct: 507 EVQSPLAEETTAEEASAEIQLLAAI-EAPADETPAEAQS-----PLSEET-----SAEEA 555
Query: 271 PGDPASPPAPGSPTPQ-------PNGE--------------CHSLGTARGSPEEELPLPA 309
P + SP A G + P+GE + +A +P E P PA
Sbjct: 556 PAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPA 615
Query: 310 FE---KLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEG 366
E ++ P P P + P E + +V+ P P + EE
Sbjct: 616 EEAPAEVQPPPAEEAPAEVQPPPA--EEAPAEVQPPPAEEAP-------AEVQPPPAEEA 666
Query: 367 SERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPA 426
+P P PA Q+ P + +P TL+A S + + V + A VD+ PPA
Sbjct: 667 PAEVQPPPAEEAPAEVQSLPAEE-TPIEETLAAVHSPPADD----VPAEEASVDKHSPPA 721
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 49.7 bits (117), Expect = 7e-06
Identities = 88/341 (25%), Positives = 127/341 (37%), Gaps = 59/341 (17%)
Query: 215 PGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDP 274
P +P P PTS PE+ L+ PL E + + + E P
Sbjct: 444 PEESPLSPPPEESPTS------PPPEASRLSPPPEELPASPLPEALHLSRPLEES----P 493
Query: 275 ASPP---APGSPTPQPNGECHSLGTARGSPEEELPLPAFEK-LNPYPTPSPPHPLYPGRR 330
SPP +P SP P+ + + PEE P PA E L+P P SP P +
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF---- 549
Query: 331 VIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARP---SPVPSTPASAQASPH 387
E+ P LP T +A LS E S + P SP+ P +++ P
Sbjct: 550 -----EESPLSPPPEELP--TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 388 HQPSP-------APLTLSAPASSASSE-EDLLVSWQRAFVDRTPPP--AAVAQRTAFGRD 437
+ SP +PL+ AS S ED +S +PPP + ++ R
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662
Query: 438 ALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQ 497
+ P + + P + +P++ P E+ L P DS E+ PE+
Sbjct: 663 SPPPEESPLSPPPEE------SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
Query: 498 SLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVH 538
S LP+ EE P LP PQ P+ G H
Sbjct: 717 S-LPL----EESP----------LLPLPEEPQLCPRSEGPH 742
Score = 43.5 bits (101), Expect = 5e-04
Identities = 86/339 (25%), Positives = 119/339 (35%), Gaps = 50/339 (14%)
Query: 215 PGPAPSLAPGAVVPTS--------VIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDM 266
PG P+ P A+ V + ++P L + G AG L + +
Sbjct: 377 PGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQL--EAPL 434
Query: 267 SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPE-EELPLPAFEKLNPYPTPSPPHPL 325
+E +P P +P SP P+ + +R SP EELP + P PL
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL 494
Query: 326 YPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASA--Q 383
P S P +SP ++ + LS EE PSP TP S +
Sbjct: 495 SPPPEESPLSPP----PESSP-----FSPLEESPLSPPEESP----PSPALETPLSPPPE 541
Query: 384 ASPHHQP------SPAPLTL-SAPASSASS----EEDLLVSWQRAFVDRTPPPAAVAQRT 432
ASP P SP P L ++P AS E+ +S +PPP A
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFP 601
Query: 433 AFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISP 492
F L SP + +P + P E+ L P DS EE + P
Sbjct: 602 PFEESPL---------SPPPEE----SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648
Query: 493 EEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRS 531
E R S LP+ P S P+S P+ S
Sbjct: 649 EVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687
Score = 42.7 bits (99), Expect = 9e-04
Identities = 71/273 (26%), Positives = 89/273 (32%), Gaps = 27/273 (9%)
Query: 274 PASPP---APGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRR 330
P SPP +P SP P+ + +R SP P L+P P SP P R
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP-----PEESPLSPPPEESPTSPPPEASR 688
Query: 331 VIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQAS--PHH 388
+ ED P P +SL L E + P+P P S PH
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL-----EESPLLPLPEEPQLCPRSEGPHL 743
Query: 389 QPSPAPLTLSA----PASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQR 444
P P LS P S +EE L P A G P+ +
Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803
Query: 445 HFAHSPADRDEVVQAP-----SARPEESELLLPTEPDSGFPREEEELNLPISPEEERQSL 499
+ + P S +PEES L +E PR EE +SPE E+ L
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEES---HLSPELEKPPL 860
Query: 500 LPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSP 532
P E PG P P SP
Sbjct: 861 SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSP 893
Score = 42.4 bits (98), Expect = 0.001
Identities = 94/387 (24%), Positives = 140/387 (36%), Gaps = 66/387 (17%)
Query: 211 EAASPGPAPSLAPGAVVPTSV-IARVLEK------PESLLLNSAQSGSAGRPLAEDVFVH 263
EA+ P P P + +P ++ ++R LE+ PE L+ S PL E
Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522
Query: 264 VDMSEGVPG-----------DPASPP---APGSPTPQ-----PNGECHSLG-----TARG 299
+ S P P SPP +P SP P+ P E L +
Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582
Query: 300 SPEEELPL----------PAFEK--LNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRN--- 344
P EE P+ P FE+ L+P P SP P R+ ED P
Sbjct: 583 PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642
Query: 345 --SPLPNCTYATRQAI--SLSLVEEGSERARP---SPVPSTPASAQASPHHQPSP-APLT 396
SP P + + + LS E S + P SP P +++ SP + SP +P
Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702
Query: 397 LSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEV 456
+PAS + + + + + + P + R+ + + H + P +
Sbjct: 703 EDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762
Query: 457 VQAP----SARPEESELLLPTEPDSGFPREE--------EELNLPISPEEERQSLLPINR 504
QA S +PEE L E P+ E EEL+L EE S +P
Sbjct: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEP 822
Query: 505 GTEEGPGTSHTEGRAWPLPSSSRPQRS 531
P SH ++ S RP+ S
Sbjct: 823 CLSPQPEESHLSPQSEEPCLSPRPEES 849
Score = 38.5 bits (88), Expect = 0.016
Identities = 79/309 (25%), Positives = 105/309 (33%), Gaps = 58/309 (18%)
Query: 211 EAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGV 270
E + P P ++ + P V++R+ PE L+ S P E +S
Sbjct: 640 EESPMSPPPEVS--RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS----RLSPPP 693
Query: 271 PGDPASPPAPGSP-TPQPNGECHSLGTARGSPEEE---LPLPAFEKL-----NPYPTPSP 321
P SPP SP +P P SL P EE LPLP +L P+ +P P
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSL------PLEESPLLPLPEEPQLCPRSEGPHLSPRP 747
Query: 322 PHPLYPGRRVIEFSEDKVRIPRNSPLPN--CTYATRQAISLSLVEEG------------- 366
P R + P SP P C A + LS EG
Sbjct: 748 EEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS 807
Query: 367 --SERARPSPVPSTPA----------SAQA-----SPHHQPSPAPLTLSAPASSASSEED 409
+E SPVP P S Q+ SP + S L P S E+
Sbjct: 808 PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP 867
Query: 410 LLVSWQRAFVDRTP---PPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEE 466
Q + P PP + G AL E SP +E+ +PS P
Sbjct: 868 PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP-PLSPLP-EELPLSPSGEPSL 925
Query: 467 SELLLPTEP 475
S L+P +P
Sbjct: 926 SPQLMPPDP 934
Score = 32.3 bits (72), Expect = 1.2
Identities = 67/269 (24%), Positives = 97/269 (36%), Gaps = 37/269 (13%)
Query: 278 PAPGSPTPQPNGECHSL----GTARGSPEEELPLPAF---EKLNPYPTPSPPHPLYP-GR 329
P PG P P P G + +G P P ++ YP PH L P G
Sbjct: 2862 PGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGL 2921
Query: 330 RVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQ 389
R + S + P P P ++ SL + P + S
Sbjct: 2922 RGLAVSGLPPQKPSAPPAPE--------LNNSLHPTPHTKGPTLPTGLELVNRPPSSTEL 2973
Query: 390 PSPAPLTLSA---PASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHF 446
P PL L A P ++D + + D + A G D L L+
Sbjct: 2974 GRPNPLALEAGKLPCEDPELDDD-FDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLE 3032
Query: 447 AHSPADRDEVVQAPSARPEESELLLPTEP--DSGFPRE--EEELNLPISPEE--ERQSLL 500
+ P D+++ +E +LL T+P D+G ++ E L L S E ER++LL
Sbjct: 3033 TNDP-HLDDLLNG-----DEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALL 3086
Query: 501 PINRGTEEGPGTSHTEGRAWPLPSSSRPQ 529
RG E PG E R P +S P+
Sbjct: 3087 ---RGVE--PGPLGPEERPPPAADASEPR 3110
>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
sapiens]
Length = 907
Score = 48.9 bits (115), Expect = 1e-05
Identities = 91/405 (22%), Positives = 139/405 (34%), Gaps = 87/405 (21%)
Query: 212 AASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVP 271
A +P PAP++A A T+ A + SA + + P A D+F D+ E P
Sbjct: 520 ATAPSPAPAVAAAAAATTAATAAAT----TTTTTSAATATTAPP-ALDIFG--DLFESTP 572
Query: 272 GDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFE------KLNPYPTPSPPHPL 325
A+P P P+ + S P+ P+P ++ + PSP
Sbjct: 573 EVAAAP----KPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTA 628
Query: 326 YPGR----RVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEE-GSERARPSPVPSTPA 380
P + VI+ D + P P A+ + S L+ G PSP P TPA
Sbjct: 629 SPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPA 688
Query: 381 SAQASPHHQPSPAPLTLSAPASSASSEEDLLV--------------SWQRAFVDRTPPPA 426
QP+ + P++S+SS D V + Q A V PP
Sbjct: 689 QNNLL---QPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSP 745
Query: 427 AVAQRTAFGRD---ALPELQRHFAHS---------------------------------- 449
A+A A G D +L L + S
Sbjct: 746 AMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWS 805
Query: 450 -----PADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQSLLPINR 504
A V S+ P + +P +GF +P+ P++ P+ R
Sbjct: 806 AGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMR 865
Query: 505 ---GTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSL 546
G PGT + P P+S P++ P + + L+ KD L
Sbjct: 866 PPFGAAAVPGTQLSPS---PTPASQSPKKPPAKDPLADLNIKDFL 907
Score = 47.0 bits (110), Expect = 5e-05
Identities = 71/299 (23%), Positives = 104/299 (34%), Gaps = 38/299 (12%)
Query: 212 AASPGPAPSLAPGAVVPTSV--IARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEG 269
AASPG AP+ + GA P + +A L+ + GSA D+F
Sbjct: 445 AASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETS 504
Query: 270 VPG-DPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPG 328
VP P + AP P P+ A + + + P L
Sbjct: 505 VPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIF 564
Query: 329 RRVIEFSEDKVRIPRNSPLPNCTYATRQAIS-----LSLVEEGSERAR-------PSPVP 376
+ E + + P+ P+ + A S S V E S A +P P
Sbjct: 565 GDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSP 624
Query: 377 STPAS---------------AQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDR 421
+T AS A S +P PA S ASS+S+ DLL + +F+
Sbjct: 625 ATTASPAKVDSSGVIDLFGDAFGSSASEPQPA----SQAASSSSASADLLAGFGGSFMAP 680
Query: 422 TPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFP 480
+P P AQ P + F +P+ PS +LL+PT +G P
Sbjct: 681 SPSPVTPAQNNLL----QPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQP 735
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 48.9 bits (115), Expect = 1e-05
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 21/151 (13%)
Query: 19 RELRLEIPGSRLEQEEPLTDAERMKLLQEEN---------EELRRRLASATRRTEALERE 69
R LR+E +++ E L + KL +EEN E L++R+A + EA R
Sbjct: 71 RVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRS 130
Query: 70 LEIGQDCLELELGQSRE---------ELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
DC +L L + E EL+ + K + L++S +T Q L +L L
Sbjct: 131 ---KNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELEKLK 187
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKL 151
SL+ S++ K K + I ELT KL
Sbjct: 188 SLTLSFVSERKYLNEKEKENEKLIKELTQKL 218
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 48.9 bits (115), Expect = 1e-05
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 21/151 (13%)
Query: 19 RELRLEIPGSRLEQEEPLTDAERMKLLQEEN---------EELRRRLASATRRTEALERE 69
R LR+E +++ E L + KL +EEN E L++R+A + EA R
Sbjct: 71 RVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRS 130
Query: 70 LEIGQDCLELELGQSRE---------ELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
DC +L L + E EL+ + K + L++S +T Q L +L L
Sbjct: 131 ---KNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELEKLK 187
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKL 151
SL+ S++ K K + I ELT KL
Sbjct: 188 SLTLSFVSERKYLNEKEKENEKLIKELTQKL 218
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 48.5 bits (114), Expect = 2e-05
Identities = 82/303 (27%), Positives = 110/303 (36%), Gaps = 62/303 (20%)
Query: 274 PASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAF-EKLNPYPTPSPPHPLYPGRRVI 332
P P P +G C + R +P P P++ ++ TPSPP P P +
Sbjct: 1115 PPMPERSHLTEPSSSGGCLVTPSRRETPS---PTPSYGQQSTATLTPSPPDPPQPPTDMP 1171
Query: 333 EFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSP 392
+ R+P P +S+S G ARP+ + + PA ASPH PSP
Sbjct: 1172 HLHQMPRRVPLGPSSP---------LSVSQPMLGIREARPAGLGAGPA---ASPHLSPSP 1219
Query: 393 APLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPAD 452
AP T ASSA +WQ + TPP R ALP + +SP D
Sbjct: 1220 APST----ASSAPGR-----TWQ-GNGEMTPPLQGPRARFRKKPKALPYRRE---NSPGD 1266
Query: 453 RDEVVQAPSARPEESELLLPTE------------PDSGFPREEEELNLP----ISPEEE- 495
+ P P E E E SG + + + L + P+EE
Sbjct: 1267 ----LPPPPLPPPEEEASWALELRAAGSMSSLERERSGERKAVQAVPLAAQRVLHPDEEA 1322
Query: 496 -----RQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ 550
R S L +GT R SSSR R P R R S +Q+Q
Sbjct: 1323 WLPYSRPSFLSRGQGTSTCSTAGSNSSRG---SSSSRGSRGPGR----SRSRSQSRSQSQ 1375
Query: 551 EQG 553
G
Sbjct: 1376 RPG 1378
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 48.5 bits (114), Expect = 2e-05
Identities = 36/140 (25%), Positives = 74/140 (52%), Gaps = 7/140 (5%)
Query: 31 EQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDK 90
EQ++ T+ R+KLLQEENE+L+ R RR L+R++E L+ + +++E L K
Sbjct: 814 EQDQAGTEM-RVKLLQEENEKLQGRSEELERRVAQLQRQIE----DLKGDEAKAKETLKK 868
Query: 91 FKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNK 150
++ + R+L+ + +++ +E L + + + + ++K L ++ E + +
Sbjct: 869 YEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQ 928
Query: 151 LLDAKNTINKLEELNERYRL 170
+ N++E NER+ L
Sbjct: 929 KEQLRRLKNEME--NERWHL 946
Score = 32.3 bits (72), Expect = 1.2
Identities = 35/150 (23%), Positives = 65/150 (43%), Gaps = 13/150 (8%)
Query: 38 DAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRR 97
D + + + +EE E+L R+ EREL + L+ E+ +E+DK K+++
Sbjct: 738 DLQDLLIAKEEQEDLLRKR----------ERELTALKGALKEEVSSHDQEMDKLKEQY-- 785
Query: 98 LQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNT 157
A + + +E + LAS S++ EM K L E +L + + +
Sbjct: 786 -DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERR 844
Query: 158 INKLEELNERYRLDCNLAVQLLKCNKSHFR 187
+ +L+ E + D A + LK + R
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIR 874
Score = 30.4 bits (67), Expect = 4.5
Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 8/97 (8%)
Query: 31 EQEEPLTDAERMKL-LQEENEELRRRLASATRRTEALERELEIGQDCLELELG------- 82
E E+ L ER + LQ N L R++ + + L +D L L L
Sbjct: 1157 ELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVE 1216
Query: 83 QSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTL 119
++ EE+D+ + ++LQ N+ L+ +L+++
Sbjct: 1217 EAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSM 1253
Score = 29.3 bits (64), Expect = 9.9
Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 28/143 (19%)
Query: 19 RELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLE 78
R+L+LE+ + +EE ERM+ EELR + L++ LE E
Sbjct: 628 RQLQLEVKNQQNIKEE----RERMR---ANLEELRSQHNEKVEENSTLQQRLEES----E 676
Query: 79 LELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRK 138
EL ++ EEL F+ K R Q+ Q ++L+D+L S H + + K++E
Sbjct: 677 GELRKNLEEL--FQVKMEREQH-----QTEIRDLQDQL----SEMHDELDSAKRSE---- 721
Query: 139 TLDWEIVELTNKLLDAKNTINKL 161
D E L +LL AK + L
Sbjct: 722 --DREKGALIEELLQAKQDLQDL 742
Score = 29.3 bits (64), Expect = 9.9
Identities = 33/153 (21%), Positives = 66/153 (43%), Gaps = 7/153 (4%)
Query: 17 EHRELRLEIPGSRLEQEEPLTDA----ERMKLLQEENEELRRRLASATRRTEALERELEI 72
E E++ ++ LE E+ A + M+L++EE + +R A + + LE+ L+
Sbjct: 985 ELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKD 1044
Query: 73 GQDCLELE--LGQSREELDK-FKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFA 129
+ LE + L R L K +DK +L+ + + L +++
Sbjct: 1045 LEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNE 1104
Query: 130 IKKAEMDRKTLDWEIVELTNKLLDAKNTINKLE 162
+ + R+ L+ + + L + D K+ I LE
Sbjct: 1105 LLQERAARQDLECDKISLERQNKDLKSRIIHLE 1137
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 48.1 bits (113), Expect = 2e-05
Identities = 65/247 (26%), Positives = 86/247 (34%), Gaps = 59/247 (23%)
Query: 203 RKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLL-NSAQSGSAGRPLAEDVF 261
++ + G+ PG S AP +P I+ L P S L N++++ A R
Sbjct: 114 QRDVAGGKTGQGPG---SRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP--- 167
Query: 262 VHVDMSEGVPGDPA-SPPAPGSPTPQPNGECHSLGTARGSPEEEL----------PLPAF 310
VP P +PP P P P P + T SP L P+P
Sbjct: 168 -----RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC- 221
Query: 311 EKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSP------------LPNCTYATRQAI 358
P P P PP P P DK P+ +P LP C Y +A
Sbjct: 222 ---APPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAE 278
Query: 359 SLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAF 418
S ++ E P+P P P A SP PL P ++SSE
Sbjct: 279 PASPAQDAQE--PPAPPPPLPPYASCSPRASLPAPPL----PGVNSSSE----------- 321
Query: 419 VDRTPPP 425
TPPP
Sbjct: 322 ---TPPP 325
Score = 36.6 bits (83), Expect = 0.062
Identities = 83/381 (21%), Positives = 118/381 (30%), Gaps = 94/381 (24%)
Query: 214 SPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLA---EDVFVHVDMSEGV 270
+P P P AP TS + R K S LL Q G+ R + + ++ S+G
Sbjct: 20 APPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGT 79
Query: 271 PGD---------PASPP------APGSPTPQPNGECHSLGTARG------SPEEELP--- 306
+ ++PP A G P +P G+ G G +P LP
Sbjct: 80 NKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKT 139
Query: 307 ------LPAFEKLN---------------------PYPTPSPPHPLYPGRRVIEFSEDKV 339
PA +L P PTP PP P P
Sbjct: 140 ISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLP-----------P 188
Query: 340 RIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSA 399
+P +SP+ + ++ +G+ PVP P P P P P
Sbjct: 189 PLPSSSPIKTPLVSPPGPLT-----KGNLPVVAPPVPCAP------PPPPPPPPPTPPPL 237
Query: 400 PASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQA 459
P +S S++ + + PPP + + P L+ A D E
Sbjct: 238 PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY-----PGLKAEPASPAQDAQEPPAP 292
Query: 460 PSARPE----ESELLLPTEPDSGFPREEEELNLPISPEEERQSLLPINRGTEEGPGTSHT 515
P P LP P G E P+ P+ P G + P
Sbjct: 293 PPPLPPYASCSPRASLPAPPLPGV-NSSSETPPPLPPKSPSFQAPPQKAGAQALP----- 346
Query: 516 EGRAWPLPSSSRPQRSPKRMG 536
A P P S+P KR G
Sbjct: 347 ---APPAPPGSQPFLQKKRHG 364
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 47.8 bits (112), Expect = 3e-05
Identities = 69/282 (24%), Positives = 96/282 (34%), Gaps = 33/282 (11%)
Query: 267 SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLY 326
S VPG P P +P P P +LG G + PL + +P+ PP P
Sbjct: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALG---GGSIRQSPLSSS---SPFSN-RPPLPPT 255
Query: 327 PGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTP---ASAQ 383
P R + +DK P P R +I V + PVPSTP AS+Q
Sbjct: 256 PSRAL----DDK------PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ 305
Query: 384 ASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQ 443
A P P P P SS+ ++E + + + + PP R+ E
Sbjct: 306 APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365
Query: 444 RHFAHSPADRDEVVQAPS--ARPEESELLLPTEPD----SGFPREEEELNLPISPEEERQ 497
P R + P +R + LP P SG P+ P+
Sbjct: 366 PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425
Query: 498 SLLP-------INRGTEEGPGTSHTEGRAWPLPSSSRPQRSP 532
P I G ++ P E R + P S P P
Sbjct: 426 GAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
Score = 43.9 bits (102), Expect = 4e-04
Identities = 54/197 (27%), Positives = 69/197 (35%), Gaps = 45/197 (22%)
Query: 372 PSPVPSTPASAQASPHH-----------QPSPAPLTLSAP-------------------A 401
P PVPSTP Q+SPH+ QPSP P P +
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 402 SSASSEEDLLVSWQRAFVDR-TPPPAAVAQRTAFGRDAL----PELQRHFAHSPADRDEV 456
S S+ L + RA D+ PPP V R + R+A+ P+ + S
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303
Query: 457 VQAPSARPEESELLLPTEPDSGFPREE----EELNLPIS------PEEERQSLLPINRGT 506
QAP P S P P S +E + NL +S P R LP
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363
Query: 507 EEGPGTSHTEGRAWPLP 523
P GR+ PLP
Sbjct: 364 RPPPPVRDPPGRSGPLP 380
Score = 30.8 bits (68), Expect = 3.4
Identities = 60/227 (26%), Positives = 75/227 (33%), Gaps = 53/227 (23%)
Query: 268 EGVPGDPAS---PPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLN---------- 314
E VP P PP P +P P + + P PLP N
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQRN 338
Query: 315 --------PYPTPSPPHPLYPGRRVIEFSEDKVRIP--RNSPLP------------NCTY 352
P P+P PL P E VR P R+ PLP
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPS--ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
Query: 353 ATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLV 412
AT Q S S V+ RP P+P SA A P P P T S ED
Sbjct: 397 ATPQLPSRSGVDSPRSGPRP-PLPPDRPSAGA----PPPPPPSTSIRNGFQDSPCED--- 448
Query: 413 SWQRAF----VDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDE 455
W+ F + PPP Q T + +L R+ + S ++R E
Sbjct: 449 EWESRFYFHPISDLPPPEPYVQTT---KSYPSKLARNESRSGSNRRE 492
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 47.8 bits (112), Expect = 3e-05
Identities = 69/282 (24%), Positives = 96/282 (34%), Gaps = 33/282 (11%)
Query: 267 SEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLY 326
S VPG P P +P P P +LG G + PL + +P+ PP P
Sbjct: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALG---GGSIRQSPLSSS---SPFSN-RPPLPPT 255
Query: 327 PGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTP---ASAQ 383
P R + +DK P P R +I V + PVPSTP AS+Q
Sbjct: 256 PSRAL----DDK------PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ 305
Query: 384 ASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQ 443
A P P P P SS+ ++E + + + + PP R+ E
Sbjct: 306 APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365
Query: 444 RHFAHSPADRDEVVQAPS--ARPEESELLLPTEPD----SGFPREEEELNLPISPEEERQ 497
P R + P +R + LP P SG P+ P+
Sbjct: 366 PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425
Query: 498 SLLP-------INRGTEEGPGTSHTEGRAWPLPSSSRPQRSP 532
P I G ++ P E R + P S P P
Sbjct: 426 GAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
Score = 43.9 bits (102), Expect = 4e-04
Identities = 54/197 (27%), Positives = 69/197 (35%), Gaps = 45/197 (22%)
Query: 372 PSPVPSTPASAQASPHH-----------QPSPAPLTLSAP-------------------A 401
P PVPSTP Q+SPH+ QPSP P P +
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 402 SSASSEEDLLVSWQRAFVDR-TPPPAAVAQRTAFGRDAL----PELQRHFAHSPADRDEV 456
S S+ L + RA D+ PPP V R + R+A+ P+ + S
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303
Query: 457 VQAPSARPEESELLLPTEPDSGFPREE----EELNLPIS------PEEERQSLLPINRGT 506
QAP P S P P S +E + NL +S P R LP
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363
Query: 507 EEGPGTSHTEGRAWPLP 523
P GR+ PLP
Sbjct: 364 RPPPPVRDPPGRSGPLP 380
Score = 30.8 bits (68), Expect = 3.4
Identities = 60/227 (26%), Positives = 75/227 (33%), Gaps = 53/227 (23%)
Query: 268 EGVPGDPAS---PPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLN---------- 314
E VP P PP P +P P + + P PLP N
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQRN 338
Query: 315 --------PYPTPSPPHPLYPGRRVIEFSEDKVRIP--RNSPLP------------NCTY 352
P P+P PL P E VR P R+ PLP
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPS--ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
Query: 353 ATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLV 412
AT Q S S V+ RP P+P SA A P P P T S ED
Sbjct: 397 ATPQLPSRSGVDSPRSGPRP-PLPPDRPSAGA----PPPPPPSTSIRNGFQDSPCED--- 448
Query: 413 SWQRAF----VDRTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDE 455
W+ F + PPP Q T + +L R+ + S ++R E
Sbjct: 449 EWESRFYFHPISDLPPPEPYVQTT---KSYPSKLARNESRSGSNRRE 492
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 47.8 bits (112), Expect = 3e-05
Identities = 81/338 (23%), Positives = 114/338 (33%), Gaps = 67/338 (19%)
Query: 212 AASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVP 271
A+SP P P+ +P A +S ++ L + + + A PL + + +S P
Sbjct: 1411 ASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGP 1470
Query: 272 G---------DPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPP 322
P P APG P+ P+G S L L L+ TP
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALT------LGLATAPSLSSSQTPG-- 1522
Query: 323 HPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPSTPASA 382
HPL + P +S +P A S LV A SP PS P
Sbjct: 1523 HPL-------------LLAPTSSHVPGLNSTVAPACSPVLVPAS---ALASPFPSAP--- 1563
Query: 383 QASPHHQPSPAPLTLSAPASSASSEEDL----LVSWQRAFVDRTP-PPAAVAQRTAFGRD 437
P+PA +L APASSAS + + Q A + +P PP A A
Sbjct: 1564 ------NPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPG 1617
Query: 438 ALPELQRH------FAHSPADRDEVVQA-------PSARPEESELLLPTEPDSGFPREEE 484
A P L A S + A P P ++ +LP S P
Sbjct: 1618 AAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPAS 1677
Query: 485 ELNLPISPE-------EERQSLLPINRGTEEGPGTSHT 515
L ++P L + G +GP + T
Sbjct: 1678 TQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQT 1715
Score = 31.6 bits (70), Expect = 2.0
Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 10/83 (12%)
Query: 214 SPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVP-- 271
SP P P+L P A ++ + P S + S S PL + + +S+ P
Sbjct: 1791 SPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDT 1850
Query: 272 ----GDPASPPAP----GSPTPQ 286
P SPP+ G P P+
Sbjct: 1851 LTLRSGPPSPPSTATSFGGPRPR 1873
Score = 31.2 bits (69), Expect = 2.6
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 52/197 (26%)
Query: 211 EAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGV 270
+A +P P P+ P +V+P+S + P L L A + + V + + +
Sbjct: 1261 QAVAPTPGPT--PVSVLPSSTPSTT-PAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQA- 1316
Query: 271 PGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRR 330
P D +P P +P P+P P LP LNP PT L PGR
Sbjct: 1317 PRDGLTPVPPLAPAPRP-------------PSSGLPAV----LNPRPT------LTPGR- 1352
Query: 331 VIEFSEDKVRIPRNSPLPNCTYATRQA-ISLSLVEEGSERARPSPVPSTPASAQASPHHQ 389
LP T T +A + + + SP P ASA
Sbjct: 1353 ----------------LPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASA------- 1389
Query: 390 PSPAPLTLSAPASSASS 406
P APLT+S+P SS
Sbjct: 1390 PGAAPLTISSPLHVPSS 1406
Score = 29.3 bits (64), Expect = 9.9
Identities = 52/182 (28%), Positives = 74/182 (40%), Gaps = 27/182 (14%)
Query: 324 PLYPGRRVIEF---SEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERA-RPSPVPS-T 378
P PG RV E + + + ++P+ + + TR + ER RP+P P T
Sbjct: 2388 PERPGTRVSERLRGARAETQGANHTPVISA-HQTRSTTTPPRCSPARERVPRPAPRPRPT 2446
Query: 379 PASAQAS-PHHQPSP--APLTLSAPASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFG 435
PASA A+ P P P AP+ +SAP +L S PPP+ + ++
Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPS--------PPPPSQIPPCSSPA 2498
Query: 436 RDALPELQRHFAHSPADRDEVVQAPSARPEESELLL--PTEPDSGFPREEEELNLPISPE 493
P AH+P + PS S LLL P+ P S L L + PE
Sbjct: 2499 CTPPPACTPPPAHTPPPAQTCLVTPS-----SPLLLGPPSVPISA---SVTNLPLGLRPE 2550
Query: 494 EE 495
E
Sbjct: 2551 AE 2552
>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
Length = 508
Score = 47.8 bits (112), Expect = 3e-05
Identities = 40/139 (28%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 40 ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREE-----------L 88
ER + LQ+EN ELRR LA+ EA ELE + L +LG+ R E L
Sbjct: 91 EREERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARAL 150
Query: 89 DKFKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELT 148
+ ++ RL + +T QEL+ +L L + A + ++L E L
Sbjct: 151 SELSEQNLRLSQQLAQASQTEQELQRELDALRGQCQAQALAGAELRTRLESLQGENQMLQ 210
Query: 149 NKLLDAKNTINKLEELNER 167
++ D + I L E E+
Sbjct: 211 SRRQDLEAQIRGLREEVEK 229
Score = 32.0 bits (71), Expect = 1.5
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 10/82 (12%)
Query: 12 RKAPPEHRELRL-EIPGSRL-----EQEEPLTDAERMKL----LQEENEELRRRLASATR 61
R+ +ELR E PG L +++E + A + L + E + L R L A R
Sbjct: 381 REELQRQKELRAQEDPGEALHSALSDRDEAVNKALELSLQLNRVSLERDSLSRELLRAIR 440
Query: 62 RTEALERELEIGQDCLELELGQ 83
+ AL +ELE QD +++ +GQ
Sbjct: 441 QKVALTQELEAWQDDMQVVIGQ 462
Score = 31.2 bits (69), Expect = 2.6
Identities = 35/131 (26%), Positives = 58/131 (44%), Gaps = 22/131 (16%)
Query: 13 KAPPEHRELRLEIPGSRLE-QEEPLTDAE---RMKLLQEENEELRRRLASATRRTEALER 68
+A +EL+ E+ R + Q + L AE R++ LQ EN+ L+ R + L
Sbjct: 166 QASQTEQELQRELDALRGQCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLRE 225
Query: 69 ELEIGQDCLE-----------------LELGQSREELDKFKDKFRRLQNSYTASQRTNQE 111
E+E G+ L+ LEL ++R E + RRLQ + + ++
Sbjct: 226 EVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESR- 284
Query: 112 LEDKLHTLASL 122
L+D + ASL
Sbjct: 285 LQDADVSAASL 295
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 47.4 bits (111), Expect = 4e-05
Identities = 82/336 (24%), Positives = 123/336 (36%), Gaps = 55/336 (16%)
Query: 213 ASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPG 272
ASP +PS P + P S+ A L+ P S + S SA P + +
Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
Query: 273 DPASPPAPGSPTPQ--PNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRR 330
P +PPA +P Q P+ G A SP LP ++P TP P P
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP------MSPLATPPPQAPPVLAAP 569
Query: 331 VIEF-----SEDKVRIPRNSPLPN-CTYATRQAISLSLVEEGSERARPSPVPSTPASAQA 384
+++ + ++ PR P P T + ++L+L P P +P+S +
Sbjct: 570 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSPSSTLS 624
Query: 385 SPHHQPSPAPLTLSAPASSASSEEDLLVSWQ---RAFVDRTPPP---AAVAQRTAFGRDA 438
P L+ +SSA+S + L + +PPP A A+ R
Sbjct: 625 GP---------DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675
Query: 439 LPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQS 498
P L F +P AP LP P +G P + L I E +S
Sbjct: 676 APPLA--FRGAPG-------AP----------LPWPPATG-PGSADGL-CTIYETEGPES 714
Query: 499 LLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKR 534
P + GP + G+A + RSPK+
Sbjct: 715 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 750
Score = 40.8 bits (94), Expect = 0.003
Identities = 76/307 (24%), Positives = 106/307 (34%), Gaps = 55/307 (17%)
Query: 201 MVRKHLHSGQEAASPGPAPSLAP--------GAVVPTSVIARVLEKPESLLLNSAQSG-- 250
M R+ +G E P PAPS P +V S + P + SA G
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 251 -SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPT-PQPNGECHSLGTARGSPEEELPLP 308
A R L+ + P +P AP P+ P+P G +L + +P + P
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG-LQALRPPQVTPPRKDAAP 294
Query: 309 AFEKL--NPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEG 366
A L +P TPSP L S P AT + SL+
Sbjct: 295 ALGPLSSSPLATPSPSAAL------------------QSQAPPTLPATPHSSSLTC---- 332
Query: 367 SERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTP-PP 425
+P+P P S A P Q P+P + P+ + +S + +F+ P P
Sbjct: 333 ---QLATPLPLAPPSPSAPPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFLPSPPLSP 388
Query: 426 AAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEE 485
A A ALP LQ +P A P S L P+ P +
Sbjct: 389 LATPPPQAPPALALPPLQ------------APPSPPASPPLSPLATPS-PQAPNALAVHL 435
Query: 486 LNLPISP 492
L P SP
Sbjct: 436 LQAPFSP 442
Score = 34.7 bits (78), Expect = 0.24
Identities = 59/230 (25%), Positives = 86/230 (37%), Gaps = 32/230 (13%)
Query: 214 SPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGD 273
SPGP S PG T+ + +K L +++ ++ + G+ A + +S G D
Sbjct: 110 SPGPVSS--PGRASGTTRPGPLGQK--GLRISAEETVARGK--ATEAPKRSALSAGARRD 163
Query: 274 PASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIE 333
S P PG+P+P + GT G LP PA P P PP P + V
Sbjct: 164 -TSGPTPGTPSPAMARRSRAAGTEVG-----LPRPA-----PSARPRPPTE-GPRKSVSS 211
Query: 334 FSEDKVRIPRNSP--LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPS 391
SE P + P+ ++ S SL + + P+ + +P H
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
Query: 392 PAPLTLSA--------PASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTA 433
P P L A P A+ L S A TP P+A Q A
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA----TPSPSAALQSQA 317
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 47.4 bits (111), Expect = 4e-05
Identities = 82/336 (24%), Positives = 123/336 (36%), Gaps = 55/336 (16%)
Query: 213 ASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPG 272
ASP +PS P + P S+ A L+ P S + S SA P + +
Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476
Query: 273 DPASPPAPGSPTPQ--PNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRR 330
P +PPA +P Q P+ G A SP LP ++P TP P P
Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP------MSPLATPPPQAPPVLAAP 530
Query: 331 VIEF-----SEDKVRIPRNSPLPN-CTYATRQAISLSLVEEGSERARPSPVPSTPASAQA 384
+++ + ++ PR P P T + ++L+L P P +P+S +
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSPSSTLS 585
Query: 385 SPHHQPSPAPLTLSAPASSASSEEDLLVSWQ---RAFVDRTPPP---AAVAQRTAFGRDA 438
P L+ +SSA+S + L + +PPP A A+ R
Sbjct: 586 GP---------DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 636
Query: 439 LPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQS 498
P L F +P AP LP P +G P + L I E +S
Sbjct: 637 APPLA--FRGAPG-------AP----------LPWPPATG-PGSADGL-CTIYETEGPES 675
Query: 499 LLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKR 534
P + GP + G+A + RSPK+
Sbjct: 676 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711
Score = 34.3 bits (77), Expect = 0.31
Identities = 48/188 (25%), Positives = 73/188 (38%), Gaps = 20/188 (10%)
Query: 214 SPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGD 273
SPGP S PG T+ + +K L +++ ++ + G+ A + +S G D
Sbjct: 101 SPGPVSS--PGRASGTTRPGPLGQK--GLRISAEETVARGK--ATEAPKRSALSAGARRD 154
Query: 274 PASPPAPGSPTPQPNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIE 333
S P PG+P+P + GT G LP PA P P PP P + V
Sbjct: 155 -TSGPTPGTPSPAMARRSRAAGTEVG-----LPRPA-----PSARPRPPTE-GPRKSVSS 202
Query: 334 FSEDKVRIPRNSP--LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPS 391
SE P + P+ ++ S SL + + P+ + +P H
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262
Query: 392 PAPLTLSA 399
P P L A
Sbjct: 263 PKPKGLQA 270
Score = 34.3 bits (77), Expect = 0.31
Identities = 70/295 (23%), Positives = 91/295 (30%), Gaps = 61/295 (20%)
Query: 201 MVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDV 260
M R+ +G E P PAPS P PT + + + RP A
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224
Query: 261 FVH-VDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGSPEEELPLP-AFEKLNPYPT 318
S P S PA P+ + GT R P P + L P P
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSAR--------GTPRAPAHPSQPKPKGLQALRP-PQ 275
Query: 319 PSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISLSLVEEGSERARPSPVPST 378
+PP K P PL + AT P PS
Sbjct: 276 VTPPR--------------KDAAPALGPLSSSPLAT-------------------PSPSA 302
Query: 379 PASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVDRTP-PPAAVAQRTAFGRD 437
P S A P Q P+P + P+ + +S + +F+ P P A A
Sbjct: 303 PPSPSAPPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361
Query: 438 ALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISP 492
ALP LQ +P A P S L P+ P + L P SP
Sbjct: 362 ALPPLQ------------APPSPPASPPLSPLATPS-PQAPNALAVHLLQAPFSP 403
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 47.0 bits (110), Expect = 5e-05
Identities = 43/179 (24%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Query: 32 QEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKF 91
QE A+ ++ L E+ E+ +R A+ + + LE+E L + LGQ+++E++
Sbjct: 1195 QEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVEHK 1253
Query: 92 KDKF----RRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVEL 147
K K + LQ+ + +R EL DK+H L + S + +AE L ++ L
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 148 TNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHL 206
+++L D + E L E R N++ +L + + D E + + +H+
Sbjct: 1314 SSQLQDTQ------ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1366
Score = 38.9 bits (89), Expect = 0.013
Identities = 50/199 (25%), Positives = 88/199 (44%), Gaps = 36/199 (18%)
Query: 8 KKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKL--LQEENEELRRRLASATRRTEA 65
K+ +KA E +EL E S+L +E+ L + L E EE+R RLA+ + E
Sbjct: 865 KERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 66 LERELE-------------------IGQDCLELELGQSREELDKFKDKFRRLQNSYTASQ 106
+ E+E + Q L+LE E+L++ + ++LQ ++
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE-----EQLEEEEAARQKLQLEKVTAE 977
Query: 107 RTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEEL-N 165
++LED++ + ++ K +RK L+ I +LT L + + L +L N
Sbjct: 978 AKIKKLEDEILVMDDQNN-------KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
Query: 166 ERYRLDCNLAVQLLKCNKS 184
+ + L V+L K KS
Sbjct: 1031 KHESMISELEVRLKKEEKS 1049
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/138 (20%), Positives = 58/138 (42%), Gaps = 11/138 (7%)
Query: 31 EQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDK 90
E + L + +++ L+EE L+ +L + LER + L ++L S+++L
Sbjct: 1327 ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI----STLNIQLSDSKKKLQD 1382
Query: 91 FKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNK 150
F L+ Q+ + L + A+ A K E + L E+ +L
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAA-------AYDKLEKTKNRLQQELDDLVVD 1435
Query: 151 LLDAKNTINKLEELNERY 168
L + + ++ LE+ ++
Sbjct: 1436 LDNQRQLVSNLEKKQRKF 1453
Score = 33.5 bits (75), Expect = 0.53
Identities = 46/203 (22%), Positives = 79/203 (38%), Gaps = 39/203 (19%)
Query: 9 KPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRTEALER 68
K K+ E +L+ ++ G + E + D LQ + EL+ +LA E
Sbjct: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIAD------LQAQIAELKMQLAKK-------EE 1090
Query: 69 ELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIF 128
EL+ L+ E+ Q L K + ELE + L S
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIR------------------ELEGHISDLQEDLDSERA 1132
Query: 129 AIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRN 188
A KAE ++ L E+ L +L D ++ +EL + + + L K R+
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRS 1189
Query: 189 HKFADLPCELQDMVRKHLHSGQE 211
H+ ++Q+M +KH + +E
Sbjct: 1190 HE-----AQVQEMRQKHAQAVEE 1207
Score = 33.5 bits (75), Expect = 0.53
Identities = 55/220 (25%), Positives = 89/220 (40%), Gaps = 37/220 (16%)
Query: 17 EHRELRLEIPGSRLEQEEPLTDAERMKLLQE-ENEELRRRLASATRRTEALE---RELEI 72
E+ + + ++ +E L AER + + E EEL LAS+ AL+ R LE
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 1736
Query: 73 GQDCLELELGQSREELDKFKDKFRR-------LQNSYTASQRT-------NQELEDKLHT 118
LE EL + + ++ D+ R+ L N + T Q+LE +
Sbjct: 1737 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Query: 119 LASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQL 178
L S H A+K + T L+AK I +LEE E+ + A +
Sbjct: 1797 LRSKLHEMEGAVKSK-----------FKSTIAALEAK--IAQLEEQVEQEAREKQAATKS 1843
Query: 179 LKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPA 218
LK ++ K ++ +++D RK +E A G A
Sbjct: 1844 LK-----QKDKKLKEILLQVED-ERKMAEQYKEQAEKGNA 1877
Score = 30.4 bits (67), Expect = 4.5
Identities = 48/216 (22%), Positives = 95/216 (43%), Gaps = 30/216 (13%)
Query: 4 AAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRT 63
AA AKK K + ++L L+ + +EE + ++++ LQ + ++ +R L A
Sbjct: 1615 AAAAKK---KLEGDLKDLELQADSAIKGREEAI---KQLRKLQAQMKDFQRELEDARASR 1668
Query: 64 E---ALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
+ A +E E LE +L Q +E+L A++R ++ + + LA
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDL--------------AAAERARKQADLEKEELA 1714
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQL-- 178
S + + +++ L+ I +L +L + + +E +++R R A QL
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ---GNMEAMSDRVRKATQQAEQLSN 1771
Query: 179 -LKCNKSHFRNHKFADLPCELQDM-VRKHLHSGQEA 212
L +S + ++ A E Q+ +R LH + A
Sbjct: 1772 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 47.0 bits (110), Expect = 5e-05
Identities = 43/179 (24%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Query: 32 QEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKF 91
QE A+ ++ L E+ E+ +R A+ + + LE+E L + LGQ+++E++
Sbjct: 1202 QEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVEHK 1260
Query: 92 KDKF----RRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVEL 147
K K + LQ+ + +R EL DK+H L + S + +AE L ++ L
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 148 TNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHL 206
+++L D + E L E R N++ +L + + D E + + +H+
Sbjct: 1321 SSQLQDTQ------ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1373
Score = 38.9 bits (89), Expect = 0.013
Identities = 50/199 (25%), Positives = 88/199 (44%), Gaps = 36/199 (18%)
Query: 8 KKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKL--LQEENEELRRRLASATRRTEA 65
K+ +KA E +EL E S+L +E+ L + L E EE+R RLA+ + E
Sbjct: 872 KERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 929
Query: 66 LERELE-------------------IGQDCLELELGQSREELDKFKDKFRRLQNSYTASQ 106
+ E+E + Q L+LE E+L++ + ++LQ ++
Sbjct: 930 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE-----EQLEEEEAARQKLQLEKVTAE 984
Query: 107 RTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEEL-N 165
++LED++ + ++ K +RK L+ I +LT L + + L +L N
Sbjct: 985 AKIKKLEDEILVMDDQNN-------KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037
Query: 166 ERYRLDCNLAVQLLKCNKS 184
+ + L V+L K KS
Sbjct: 1038 KHESMISELEVRLKKEEKS 1056
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/138 (20%), Positives = 58/138 (42%), Gaps = 11/138 (7%)
Query: 31 EQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDK 90
E + L + +++ L+EE L+ +L + LER + L ++L S+++L
Sbjct: 1334 ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI----STLNIQLSDSKKKLQD 1389
Query: 91 FKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNK 150
F L+ Q+ + L + A+ A K E + L E+ +L
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAA-------AYDKLEKTKNRLQQELDDLVVD 1442
Query: 151 LLDAKNTINKLEELNERY 168
L + + ++ LE+ ++
Sbjct: 1443 LDNQRQLVSNLEKKQRKF 1460
Score = 33.5 bits (75), Expect = 0.53
Identities = 46/203 (22%), Positives = 79/203 (38%), Gaps = 39/203 (19%)
Query: 9 KPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRTEALER 68
K K+ E +L+ ++ G + E + D LQ + EL+ +LA E
Sbjct: 1051 KKEEKSRQELEKLKRKLEGDASDFHEQIAD------LQAQIAELKMQLAKK-------EE 1097
Query: 69 ELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIF 128
EL+ L+ E+ Q L K + ELE + L S
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIR------------------ELEGHISDLQEDLDSERA 1139
Query: 129 AIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRN 188
A KAE ++ L E+ L +L D ++ +EL + + + L K R+
Sbjct: 1140 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRS 1196
Query: 189 HKFADLPCELQDMVRKHLHSGQE 211
H+ ++Q+M +KH + +E
Sbjct: 1197 HE-----AQVQEMRQKHAQAVEE 1214
Score = 33.5 bits (75), Expect = 0.53
Identities = 55/220 (25%), Positives = 89/220 (40%), Gaps = 37/220 (16%)
Query: 17 EHRELRLEIPGSRLEQEEPLTDAERMKLLQE-ENEELRRRLASATRRTEALE---RELEI 72
E+ + + ++ +E L AER + + E EEL LAS+ AL+ R LE
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 1743
Query: 73 GQDCLELELGQSREELDKFKDKFRR-------LQNSYTASQRT-------NQELEDKLHT 118
LE EL + + ++ D+ R+ L N + T Q+LE +
Sbjct: 1744 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1803
Query: 119 LASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQL 178
L S H A+K + T L+AK I +LEE E+ + A +
Sbjct: 1804 LRSKLHEMEGAVKSK-----------FKSTIAALEAK--IAQLEEQVEQEAREKQAATKS 1850
Query: 179 LKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPA 218
LK ++ K ++ +++D RK +E A G A
Sbjct: 1851 LK-----QKDKKLKEILLQVED-ERKMAEQYKEQAEKGNA 1884
Score = 30.4 bits (67), Expect = 4.5
Identities = 48/216 (22%), Positives = 95/216 (43%), Gaps = 30/216 (13%)
Query: 4 AAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRT 63
AA AKK K + ++L L+ + +EE + ++++ LQ + ++ +R L A
Sbjct: 1622 AAAAKK---KLEGDLKDLELQADSAIKGREEAI---KQLRKLQAQMKDFQRELEDARASR 1675
Query: 64 E---ALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
+ A +E E LE +L Q +E+L A++R ++ + + LA
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDL--------------AAAERARKQADLEKEELA 1721
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQL-- 178
S + + +++ L+ I +L +L + + +E +++R R A QL
Sbjct: 1722 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ---GNMEAMSDRVRKATQQAEQLSN 1778
Query: 179 -LKCNKSHFRNHKFADLPCELQDM-VRKHLHSGQEA 212
L +S + ++ A E Q+ +R LH + A
Sbjct: 1779 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1814
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 47.0 bits (110), Expect = 5e-05
Identities = 43/179 (24%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Query: 32 QEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKF 91
QE A+ ++ L E+ E+ +R A+ + + LE+E L + LGQ+++E++
Sbjct: 1202 QEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVEHK 1260
Query: 92 KDKF----RRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVEL 147
K K + LQ+ + +R EL DK+H L + S + +AE L ++ L
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 148 TNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHL 206
+++L D + E L E R N++ +L + + D E + + +H+
Sbjct: 1321 SSQLQDTQ------ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1373
Score = 38.9 bits (89), Expect = 0.013
Identities = 50/199 (25%), Positives = 88/199 (44%), Gaps = 36/199 (18%)
Query: 8 KKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKL--LQEENEELRRRLASATRRTEA 65
K+ +KA E +EL E S+L +E+ L + L E EE+R RLA+ + E
Sbjct: 872 KERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 929
Query: 66 LERELE-------------------IGQDCLELELGQSREELDKFKDKFRRLQNSYTASQ 106
+ E+E + Q L+LE E+L++ + ++LQ ++
Sbjct: 930 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE-----EQLEEEEAARQKLQLEKVTAE 984
Query: 107 RTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEEL-N 165
++LED++ + ++ K +RK L+ I +LT L + + L +L N
Sbjct: 985 AKIKKLEDEILVMDDQNN-------KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037
Query: 166 ERYRLDCNLAVQLLKCNKS 184
+ + L V+L K KS
Sbjct: 1038 KHESMISELEVRLKKEEKS 1056
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/138 (20%), Positives = 58/138 (42%), Gaps = 11/138 (7%)
Query: 31 EQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDK 90
E + L + +++ L+EE L+ +L + LER + L ++L S+++L
Sbjct: 1334 ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI----STLNIQLSDSKKKLQD 1389
Query: 91 FKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNK 150
F L+ Q+ + L + A+ A K E + L E+ +L
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAA-------AYDKLEKTKNRLQQELDDLVVD 1442
Query: 151 LLDAKNTINKLEELNERY 168
L + + ++ LE+ ++
Sbjct: 1443 LDNQRQLVSNLEKKQRKF 1460
Score = 33.5 bits (75), Expect = 0.53
Identities = 46/203 (22%), Positives = 79/203 (38%), Gaps = 39/203 (19%)
Query: 9 KPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRTEALER 68
K K+ E +L+ ++ G + E + D LQ + EL+ +LA E
Sbjct: 1051 KKEEKSRQELEKLKRKLEGDASDFHEQIAD------LQAQIAELKMQLAKK-------EE 1097
Query: 69 ELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIF 128
EL+ L+ E+ Q L K + ELE + L S
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIR------------------ELEGHISDLQEDLDSERA 1139
Query: 129 AIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRN 188
A KAE ++ L E+ L +L D ++ +EL + + + L K R+
Sbjct: 1140 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRS 1196
Query: 189 HKFADLPCELQDMVRKHLHSGQE 211
H+ ++Q+M +KH + +E
Sbjct: 1197 HE-----AQVQEMRQKHAQAVEE 1214
Score = 33.5 bits (75), Expect = 0.53
Identities = 55/220 (25%), Positives = 89/220 (40%), Gaps = 37/220 (16%)
Query: 17 EHRELRLEIPGSRLEQEEPLTDAERMKLLQE-ENEELRRRLASATRRTEALE---RELEI 72
E+ + + ++ +E L AER + + E EEL LAS+ AL+ R LE
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 1743
Query: 73 GQDCLELELGQSREELDKFKDKFRR-------LQNSYTASQRT-------NQELEDKLHT 118
LE EL + + ++ D+ R+ L N + T Q+LE +
Sbjct: 1744 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1803
Query: 119 LASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQL 178
L S H A+K + T L+AK I +LEE E+ + A +
Sbjct: 1804 LRSKLHEMEGAVKSK-----------FKSTIAALEAK--IAQLEEQVEQEAREKQAATKS 1850
Query: 179 LKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPA 218
LK ++ K ++ +++D RK +E A G A
Sbjct: 1851 LK-----QKDKKLKEILLQVED-ERKMAEQYKEQAEKGNA 1884
Score = 30.4 bits (67), Expect = 4.5
Identities = 48/216 (22%), Positives = 95/216 (43%), Gaps = 30/216 (13%)
Query: 4 AAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRT 63
AA AKK K + ++L L+ + +EE + ++++ LQ + ++ +R L A
Sbjct: 1622 AAAAKK---KLEGDLKDLELQADSAIKGREEAI---KQLRKLQAQMKDFQRELEDARASR 1675
Query: 64 E---ALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
+ A +E E LE +L Q +E+L A++R ++ + + LA
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDL--------------AAAERARKQADLEKEELA 1721
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQL-- 178
S + + +++ L+ I +L +L + + +E +++R R A QL
Sbjct: 1722 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ---GNMEAMSDRVRKATQQAEQLSN 1778
Query: 179 -LKCNKSHFRNHKFADLPCELQDM-VRKHLHSGQEA 212
L +S + ++ A E Q+ +R LH + A
Sbjct: 1779 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1814
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 47.0 bits (110), Expect = 5e-05
Identities = 43/179 (24%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Query: 32 QEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKF 91
QE A+ ++ L E+ E+ +R A+ + + LE+E L + LGQ+++E++
Sbjct: 1195 QEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVEHK 1253
Query: 92 KDKF----RRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVEL 147
K K + LQ+ + +R EL DK+H L + S + +AE L ++ L
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 148 TNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHL 206
+++L D + E L E R N++ +L + + D E + + +H+
Sbjct: 1314 SSQLQDTQ------ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1366
Score = 38.9 bits (89), Expect = 0.013
Identities = 50/199 (25%), Positives = 88/199 (44%), Gaps = 36/199 (18%)
Query: 8 KKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKL--LQEENEELRRRLASATRRTEA 65
K+ +KA E +EL E S+L +E+ L + L E EE+R RLA+ + E
Sbjct: 865 KERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 66 LERELE-------------------IGQDCLELELGQSREELDKFKDKFRRLQNSYTASQ 106
+ E+E + Q L+LE E+L++ + ++LQ ++
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE-----EQLEEEEAARQKLQLEKVTAE 977
Query: 107 RTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEEL-N 165
++LED++ + ++ K +RK L+ I +LT L + + L +L N
Sbjct: 978 AKIKKLEDEILVMDDQNN-------KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
Query: 166 ERYRLDCNLAVQLLKCNKS 184
+ + L V+L K KS
Sbjct: 1031 KHESMISELEVRLKKEEKS 1049
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/138 (20%), Positives = 58/138 (42%), Gaps = 11/138 (7%)
Query: 31 EQEEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDK 90
E + L + +++ L+EE L+ +L + LER + L ++L S+++L
Sbjct: 1327 ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI----STLNIQLSDSKKKLQD 1382
Query: 91 FKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNK 150
F L+ Q+ + L + A+ A K E + L E+ +L
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAA-------AYDKLEKTKNRLQQELDDLVVD 1435
Query: 151 LLDAKNTINKLEELNERY 168
L + + ++ LE+ ++
Sbjct: 1436 LDNQRQLVSNLEKKQRKF 1453
Score = 33.5 bits (75), Expect = 0.53
Identities = 46/203 (22%), Positives = 79/203 (38%), Gaps = 39/203 (19%)
Query: 9 KPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRTEALER 68
K K+ E +L+ ++ G + E + D LQ + EL+ +LA E
Sbjct: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIAD------LQAQIAELKMQLAKK-------EE 1090
Query: 69 ELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIF 128
EL+ L+ E+ Q L K + ELE + L S
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIR------------------ELEGHISDLQEDLDSERA 1132
Query: 129 AIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRN 188
A KAE ++ L E+ L +L D ++ +EL + + + L K R+
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRS 1189
Query: 189 HKFADLPCELQDMVRKHLHSGQE 211
H+ ++Q+M +KH + +E
Sbjct: 1190 HE-----AQVQEMRQKHAQAVEE 1207
Score = 33.5 bits (75), Expect = 0.53
Identities = 55/220 (25%), Positives = 89/220 (40%), Gaps = 37/220 (16%)
Query: 17 EHRELRLEIPGSRLEQEEPLTDAERMKLLQE-ENEELRRRLASATRRTEALE---RELEI 72
E+ + + ++ +E L AER + + E EEL LAS+ AL+ R LE
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 1736
Query: 73 GQDCLELELGQSREELDKFKDKFRR-------LQNSYTASQRT-------NQELEDKLHT 118
LE EL + + ++ D+ R+ L N + T Q+LE +
Sbjct: 1737 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Query: 119 LASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQL 178
L S H A+K + T L+AK I +LEE E+ + A +
Sbjct: 1797 LRSKLHEMEGAVKSK-----------FKSTIAALEAK--IAQLEEQVEQEAREKQAATKS 1843
Query: 179 LKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPA 218
LK ++ K ++ +++D RK +E A G A
Sbjct: 1844 LK-----QKDKKLKEILLQVED-ERKMAEQYKEQAEKGNA 1877
Score = 30.4 bits (67), Expect = 4.5
Identities = 48/216 (22%), Positives = 95/216 (43%), Gaps = 30/216 (13%)
Query: 4 AAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASATRRT 63
AA AKK K + ++L L+ + +EE + ++++ LQ + ++ +R L A
Sbjct: 1615 AAAAKK---KLEGDLKDLELQADSAIKGREEAI---KQLRKLQAQMKDFQRELEDARASR 1668
Query: 64 E---ALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA 120
+ A +E E LE +L Q +E+L A++R ++ + + LA
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDL--------------AAAERARKQADLEKEELA 1714
Query: 121 SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQL-- 178
S + + +++ L+ I +L +L + + +E +++R R A QL
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ---GNMEAMSDRVRKATQQAEQLSN 1771
Query: 179 -LKCNKSHFRNHKFADLPCELQDM-VRKHLHSGQEA 212
L +S + ++ A E Q+ +R LH + A
Sbjct: 1772 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,653,564
Number of Sequences: 37866
Number of extensions: 1798014
Number of successful extensions: 16965
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 1260
Number of HSP's that attempted gapping in prelim test: 11450
Number of HSP's gapped (non-prelim): 5590
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.