Search of human proteins with 225543474

Search of human proteins with 225543474

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225543474 myotubularin related protein 7 [Homo sapiens]
         (660 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225543474 myotubularin related protein 7 [Homo sapiens]           1357   0.0  
gi|134142348 myotubularin related protein 6 [Homo sapiens]            734   0.0  
gi|21361759 myotubularin related protein 8 [Homo sapiens]             717   0.0  
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]   357   2e-98
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]   357   2e-98
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]   357   2e-98
gi|4557896 myotubularin [Homo sapiens]                                346   3e-95
gi|19923424 myotubularin related protein 9 [Homo sapiens]             342   6e-94
gi|28872761 myotubularin-related protein 1 [Homo sapiens]             329   4e-90
gi|217272865 myotubularin related protein 4 [Homo sapiens]            285   1e-76
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]   281   2e-75
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]   281   2e-75
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]   281   2e-75
gi|239735519 SET binding factor 1 [Homo sapiens]                      139   8e-33
gi|29788755 SET binding factor 2 [Homo sapiens]                       132   8e-31
gi|124028527 myotubularin related protein 10 [Homo sapiens]           115   1e-25
gi|94721263 myotubularin related protein 12 [Homo sapiens]            108   1e-23
gi|224994251 myotubularin related protein 11 isoform a [Homo sap...    94   4e-19
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi...    94   4e-19
gi|239758162 PREDICTED: heterogeneous nuclear ribonucleoprotein ...    44   5e-04
gi|239752620 PREDICTED: similar to heterogeneous nuclear ribonuc...    44   5e-04
gi|226052117 heterogeneous nuclear ribonucleoprotein C-like [Hom...    44   5e-04
gi|117190254 heterogeneous nuclear ribonucleoprotein C isoform b...    41   0.003
gi|117190192 heterogeneous nuclear ribonucleoprotein C isoform a...    41   0.003
gi|117190174 heterogeneous nuclear ribonucleoprotein C isoform b...    41   0.003
gi|117189975 heterogeneous nuclear ribonucleoprotein C isoform a...    41   0.003
gi|211971067 heterogeneous nuclear ribonucleoprotein C-like [Hom...    40   0.005
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    40   0.009
gi|154816198 transcription elongation factor B polypeptide 3C-li...    38   0.034
gi|156938279 transcription elongation factor B polypeptide 3C [H...    38   0.034

>gi|225543474 myotubularin related protein 7 [Homo sapiens]
          Length = 660

 Score = 1357 bits (3511), Expect = 0.0
 Identities = 660/660 (100%), Positives = 660/660 (100%)

Query: 1   MEHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK 60
           MEHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK
Sbjct: 1   MEHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK 60

Query: 61  QATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLDK 120
           QATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLDK
Sbjct: 61  QATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLDK 120

Query: 121 EEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSS 180
           EEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSS
Sbjct: 121 EEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSS 180

Query: 181 KFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVD 240
           KFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVD
Sbjct: 181 KFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVD 240

Query: 241 TRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDF 300
           TRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDF
Sbjct: 241 TRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDF 300

Query: 301 LWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHY 360
           LWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHY
Sbjct: 301 LWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHY 360

Query: 361 RTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFN 420
           RTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFN
Sbjct: 361 RTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFN 420

Query: 421 ERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHS 480
           ERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHS
Sbjct: 421 ERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHS 480

Query: 481 QTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEE 540
           QTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEE
Sbjct: 481 QTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEE 540

Query: 541 RLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDED 600
           RLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDED
Sbjct: 541 RLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDED 600

Query: 601 SALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA 660
           SALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA
Sbjct: 601 SALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA 660


>gi|134142348 myotubularin related protein 6 [Homo sapiens]
          Length = 621

 Score =  734 bits (1896), Expect = 0.0
 Identities = 349/550 (63%), Positives = 447/550 (81%), Gaps = 7/550 (1%)

Query: 1   MEHIRTPKVENVRLVDRVSPKKAAL-GTLYLTATHVIFVENSPDPRKETWILHSQISTIE 59
           MEHIRT KVE V+L+DR S    +L GTLYLTATH++F+++    +KETWILH  I+++E
Sbjct: 1   MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSH---QKETWILHHHIASVE 57

Query: 60  KQATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLD 119
           K A T +GCPL+I+CKNF+ +  I+P+ERDCHD+Y SL++L++  KYE+LY FS+NP  +
Sbjct: 58  KLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQN 117

Query: 120 KEEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGS 179
             ER QGW LIDL+EEY RMG+PN +WQLSD NRDY++C++YP ELYVP+ A+  IIVGS
Sbjct: 118 DSERLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGS 177

Query: 180 SKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVV 239
           SKFRS+ RFPVLSYY++D  A+ICR SQPLSGFSARCLEDE +LQAI KANP + ++YV+
Sbjct: 178 SKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVM 237

Query: 240 DTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSD 299
           DTRPKLNAMANRAAGKGYENEDNYSNI+FQF+GIENIHVMR+SLQK+LEV   K  S++D
Sbjct: 238 DTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVND 297

Query: 300 FLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPH 359
           F  GLE+SGWLRHIKA+MDA IF+AKA++ E ASVLVHCSDGWDRT+QVCS+ SLLLD +
Sbjct: 298 FYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSY 357

Query: 360 YRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEF 419
           YRT+KGFMVLIEKDWISFGHKF+ R G LDGDPKE+SPV  QF+ECVW L EQFP AFEF
Sbjct: 358 YRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEF 417

Query: 420 NERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADH 479
           +E FL+ I  HI+SCQFGNFL N QKER ELK++E+TYSLW  L +++  YLNPL+ ++ 
Sbjct: 418 SEAFLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSES 477

Query: 480 SQTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALE 539
            +   T+  P T  +F +KFW  MY++F++ + PRQSV + +M + E+ +QLE++++ LE
Sbjct: 478 HRF--TVLEPNT-VSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLE 534

Query: 540 ERLEKIQKVQ 549
            ++++ +  Q
Sbjct: 535 SKIKQRKNKQ 544


>gi|21361759 myotubularin related protein 8 [Homo sapiens]
          Length = 704

 Score =  717 bits (1852), Expect = 0.0
 Identities = 335/543 (61%), Positives = 426/543 (78%), Gaps = 4/543 (0%)

Query: 1   MEHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK 60
           M+HI  PKVENV+LVDR   KK A G LYLTATH+I+VE S   RKETWI    I+T+EK
Sbjct: 1   MDHITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEK 60

Query: 61  QATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLDK 120
              T+ GCPL +RCKNF++   ++  +  CH+VYISL++L++P   E+LY FS+NP   K
Sbjct: 61  LPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSK 120

Query: 121 EEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSS 180
           E RE GW LID   ++ RMG+PN  W ++D NR+Y +C +YP E+ VPKS T   +VGSS
Sbjct: 121 EMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSS 180

Query: 181 KFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVD 240
           KFRS+ R PVLSY YK+N+A+ICR SQPLSGF  RC++DE +L+AI + NPGS F+YVVD
Sbjct: 181 KFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVD 240

Query: 241 TRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDF 300
           TRPKLNAMANRAAGKGYENEDNY+NI+F+F+GIENIHVMR+SLQK+LEVCELK+P+MS+F
Sbjct: 241 TRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEF 300

Query: 301 LWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHY 360
           L GLE+SGWLRHIKAIMDAGIFI KAV  E ASVLVHCSDGWDRTAQVCSVAS+LLDP Y
Sbjct: 301 LSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFY 360

Query: 361 RTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFN 420
           RT KG M+LIEK+WIS GHKF+ R G+LDGD KE+SP+  QF++C+WQLMEQFPCAFEFN
Sbjct: 361 RTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFN 420

Query: 421 ERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHS 480
           E FL+ I  H++SCQFGNFL N QK+R +L++ E+T+S+W  L + + D+ NPL++    
Sbjct: 421 ENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKG--F 478

Query: 481 QTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEE 540
              G L+  T P N   +FW GMYNRF+KG+QP+QS+ + L+ +K++   LE ++  LE+
Sbjct: 479 TMYGVLNPSTVPYNI--QFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEK 536

Query: 541 RLE 543
           +L+
Sbjct: 537 KLK 539


>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
          Length = 643

 Score =  357 bits (916), Expect = 2e-98
 Identities = 207/531 (38%), Positives = 307/531 (57%), Gaps = 32/531 (6%)

Query: 23  AALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK-------QATTATGCPLLIRCK 75
           A  GTL +T   + F     DP    ++L + +  I +        +       L   CK
Sbjct: 100 AVRGTLTVTNYRLYFKSMERDP---PFVLDASLGVINRVEKIGGASSRGENSYGLETVCK 156

Query: 76  NFQIIQLII-PQERDCHDVYISLIRLARPVKYE-ELYCFSFNPMLDKEEREQGWVLIDLS 133
           + + ++    P+ R    ++ +L++ A PV     L+ F +  +      E GW L D  
Sbjct: 157 DIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFP----ENGWKLYDPL 212

Query: 134 EEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSY 193
            EY R G+PN  W+++ +N  Y +CD+YP  L VP +     +   + FRSR R PVLS+
Sbjct: 213 LEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSW 272

Query: 194 YYKDNHASICRSSQPLSGFSA-RCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRA 252
            + ++ A+I R SQP+ G S  R  EDE+ LQAI  +N  S  +++ D RP +NA+AN+A
Sbjct: 273 IHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKA 332

Query: 253 AGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWL 310
            G GYE+ED Y N +  F+ I NIHVMR SL+K+ E+     P++ +  W   LE++ WL
Sbjct: 333 KGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTHWL 389

Query: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
            HIK I+   + IA  V     SV+VHCSDGWDRTAQ+ S+A L+LD +YRT++GF VL+
Sbjct: 390 EHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLV 449

Query: 371 EKDWISFGHKFNHRYGNLDGDPKEI--SPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
           EK+W+SFGH+F  R G+ D +  +   SPV  QFI+CVWQ+  QFP AFEFNE FLI I 
Sbjct: 450 EKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITIL 509

Query: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
            H+YSC FG FLCNS+++R +  + +RT SLW+++     D+ NPL+    S +   L+ 
Sbjct: 510 DHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLY---GSYSNHVLY- 565

Query: 489 PTTPCNFMYKFWSGMYNRFEKGMQPRQSVTD---YLMAVKEETQQLEEELE 536
           P      + + W G Y R+   M+P++ + +    L+A + E Q+  EEL+
Sbjct: 566 PVASMRHL-ELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQ 615


>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
          Length = 571

 Score =  357 bits (916), Expect = 2e-98
 Identities = 207/531 (38%), Positives = 307/531 (57%), Gaps = 32/531 (6%)

Query: 23  AALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK-------QATTATGCPLLIRCK 75
           A  GTL +T   + F     DP    ++L + +  I +        +       L   CK
Sbjct: 28  AVRGTLTVTNYRLYFKSMERDP---PFVLDASLGVINRVEKIGGASSRGENSYGLETVCK 84

Query: 76  NFQIIQLII-PQERDCHDVYISLIRLARPVKYE-ELYCFSFNPMLDKEEREQGWVLIDLS 133
           + + ++    P+ R    ++ +L++ A PV     L+ F +  +      E GW L D  
Sbjct: 85  DIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFP----ENGWKLYDPL 140

Query: 134 EEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSY 193
            EY R G+PN  W+++ +N  Y +CD+YP  L VP +     +   + FRSR R PVLS+
Sbjct: 141 LEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSW 200

Query: 194 YYKDNHASICRSSQPLSGFSA-RCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRA 252
            + ++ A+I R SQP+ G S  R  EDE+ LQAI  +N  S  +++ D RP +NA+AN+A
Sbjct: 201 IHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKA 260

Query: 253 AGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWL 310
            G GYE+ED Y N +  F+ I NIHVMR SL+K+ E+     P++ +  W   LE++ WL
Sbjct: 261 KGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTHWL 317

Query: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
            HIK I+   + IA  V     SV+VHCSDGWDRTAQ+ S+A L+LD +YRT++GF VL+
Sbjct: 318 EHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLV 377

Query: 371 EKDWISFGHKFNHRYGNLDGDPKEI--SPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
           EK+W+SFGH+F  R G+ D +  +   SPV  QFI+CVWQ+  QFP AFEFNE FLI I 
Sbjct: 378 EKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITIL 437

Query: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
            H+YSC FG FLCNS+++R +  + +RT SLW+++     D+ NPL+    S +   L+ 
Sbjct: 438 DHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLY---GSYSNHVLY- 493

Query: 489 PTTPCNFMYKFWSGMYNRFEKGMQPRQSVTD---YLMAVKEETQQLEEELE 536
           P      + + W G Y R+   M+P++ + +    L+A + E Q+  EEL+
Sbjct: 494 PVASMRHL-ELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQ 543


>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
          Length = 571

 Score =  357 bits (916), Expect = 2e-98
 Identities = 207/531 (38%), Positives = 307/531 (57%), Gaps = 32/531 (6%)

Query: 23  AALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK-------QATTATGCPLLIRCK 75
           A  GTL +T   + F     DP    ++L + +  I +        +       L   CK
Sbjct: 28  AVRGTLTVTNYRLYFKSMERDP---PFVLDASLGVINRVEKIGGASSRGENSYGLETVCK 84

Query: 76  NFQIIQLII-PQERDCHDVYISLIRLARPVKYE-ELYCFSFNPMLDKEEREQGWVLIDLS 133
           + + ++    P+ R    ++ +L++ A PV     L+ F +  +      E GW L D  
Sbjct: 85  DIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFP----ENGWKLYDPL 140

Query: 134 EEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSY 193
            EY R G+PN  W+++ +N  Y +CD+YP  L VP +     +   + FRSR R PVLS+
Sbjct: 141 LEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSW 200

Query: 194 YYKDNHASICRSSQPLSGFSA-RCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRA 252
            + ++ A+I R SQP+ G S  R  EDE+ LQAI  +N  S  +++ D RP +NA+AN+A
Sbjct: 201 IHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKA 260

Query: 253 AGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWL 310
            G GYE+ED Y N +  F+ I NIHVMR SL+K+ E+     P++ +  W   LE++ WL
Sbjct: 261 KGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTHWL 317

Query: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
            HIK I+   + IA  V     SV+VHCSDGWDRTAQ+ S+A L+LD +YRT++GF VL+
Sbjct: 318 EHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLV 377

Query: 371 EKDWISFGHKFNHRYGNLDGDPKEI--SPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
           EK+W+SFGH+F  R G+ D +  +   SPV  QFI+CVWQ+  QFP AFEFNE FLI I 
Sbjct: 378 EKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITIL 437

Query: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
            H+YSC FG FLCNS+++R +  + +RT SLW+++     D+ NPL+    S +   L+ 
Sbjct: 438 DHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLY---GSYSNHVLY- 493

Query: 489 PTTPCNFMYKFWSGMYNRFEKGMQPRQSVTD---YLMAVKEETQQLEEELE 536
           P      + + W G Y R+   M+P++ + +    L+A + E Q+  EEL+
Sbjct: 494 PVASMRHL-ELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQ 543


>gi|4557896 myotubularin [Homo sapiens]
          Length = 603

 Score =  346 bits (888), Expect = 3e-95
 Identities = 202/523 (38%), Positives = 306/523 (58%), Gaps = 30/523 (5%)

Query: 55  ISTIEKQA-TTATG---CPLLIRCKNFQIIQLIIPQE-RDCHDVYISLIRLARPVKYEEL 109
           IS IEK    T+ G     L I CK+ + ++  + QE     D++  L R A P+ +  L
Sbjct: 90  ISRIEKMGGATSRGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEILTRYAFPLAHS-L 148

Query: 110 YCFSFNPMLDKEEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPK 169
             F+F  + +++    GW + +  EEY R GLPNH+W+++ +N+ Y +CD+YP  L VP 
Sbjct: 149 PLFAF--LNEEKFNVDGWTVYNPVEEYRRQGLPNHHWRITFINKCYELCDTYPALLVVPY 206

Query: 170 SATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSA-RCLEDEQMLQAIRK 228
            A+   +   + FRSR R PVLS+ + +N   I R SQPL G S  R  +DE+ L  IR+
Sbjct: 207 RASDDDLRRVATFRSRNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIRE 266

Query: 229 ANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLE 288
            N     + + D RP +NA+AN+A G GYE++D Y N +  F+ I NIHVMR SL+K+ +
Sbjct: 267 TNKQISKLTIYDARPSVNAVANKATGGGYESDDAYHNAELFFLDIHNIHVMRESLKKVKD 326

Query: 289 VCELKSPSMSDFLW--GLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTA 346
           +     P++ +  W   LE++ WL HIK ++   I +A  VS   +SVLVHCSDGWDRTA
Sbjct: 327 IVY---PNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTA 383

Query: 347 QVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEI--SPVIDQFIE 404
           Q+ S+A L+LD  YR+++GF +L++K+WISFGHKF  R G+ D +  +   SP+  QFI+
Sbjct: 384 QLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASRIGHGDKNHTDADRSPIFLQFID 443

Query: 405 CVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLW 464
           CVWQ+ +QFP AFEFNE+FLI I  H+YSC+FG FL N +  R   K+ ERT SLW+ + 
Sbjct: 444 CVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFLFNCESARERQKVTERTVSLWSLIN 503

Query: 465 KNRADYLNPLFRADHSQTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAV 524
            N+  + NP +  + ++    +  P      + + W   Y R+   ++ +Q         
Sbjct: 504 SNKEKFKNPFYTKEINR----VLYPVASMRHL-ELWVNYYIRWNPRIKQQQP-------- 550

Query: 525 KEETQQLEEELEALEERLEKIQKVQL-NCTKVKSKQSEPSKHS 566
               Q+  E L   +E +++++++QL N  K+    + PS  S
Sbjct: 551 NPVEQRYMELLALRDEYIKRLEELQLANSAKLSDPPTSPSSPS 593


>gi|19923424 myotubularin related protein 9 [Homo sapiens]
          Length = 549

 Score =  342 bits (877), Expect = 6e-94
 Identities = 200/553 (36%), Positives = 311/553 (56%), Gaps = 25/553 (4%)

Query: 2   EHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEKQ 61
           E I+TP+V+NV L     P  A  GTL LT  H+I + +  D  +E W+LHS I  I+K+
Sbjct: 5   ELIKTPRVDNVVLHRPFYP--AVEGTLCLTGHHLI-LSSRQDNTEELWLLHSNIDAIDKR 61

Query: 62  ATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLDKE 121
              + G  ++I+CK+F+IIQL IP   +C ++  S+  L+       +Y F + PM   E
Sbjct: 62  FVGSLGT-IIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMF--E 118

Query: 122 EREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSK 181
             E GW      +E+         W+LS VN+++ VC SYP  + VPKS     +   + 
Sbjct: 119 VIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVAT 178

Query: 182 FRSRRRFPVLSYYYKDNHASICRSSQPLSGFSAR-CLEDEQMLQAIRKANPGSDFVYVVD 240
           FR   RFPVLSYY+K N   I RS QPL+G + R C EDE+++ A  +A       Y++D
Sbjct: 179 FRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRG---YIID 235

Query: 241 TRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDF 300
           TR    A   RA G G+E E +Y   +     IE  H+++ SL K++E C  ++ +M  +
Sbjct: 236 TRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRW 295

Query: 301 LWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHY 360
           L  LE S WL HIK I+      A+ +  EGAS+L+H ++G D T QV S+A ++L+P  
Sbjct: 296 LSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRS 355

Query: 361 RTLKGFMVLIEKDWISFGHKFNHRYGN---LDGDPKEISPVIDQFIECVWQLMEQFPCAF 417
           RT++GF  LIE++W+  GH F  R       +   K  +PV   F++CVWQ++ QFPC+F
Sbjct: 356 RTIRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSF 415

Query: 418 EFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNR----ADYLNP 473
           EFNE FLI +  H Y+ QFG FL N++ ER +LK+Q++T SLW+  W N+    + + NP
Sbjct: 416 EFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWS--WVNQPSELSKFTNP 473

Query: 474 LFRADHSQTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEE 533
           LF A++     ++   + P       W G++ R+ +  +      + ++ + E  ++L+ 
Sbjct: 474 LFEANNLVIWPSVAPQSLP------LWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQA 527

Query: 534 ELEALEERLEKIQ 546
           ++  L  +L +++
Sbjct: 528 KVNILRRQLAELE 540


>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
          Length = 665

 Score =  329 bits (844), Expect = 4e-90
 Identities = 196/557 (35%), Positives = 299/557 (53%), Gaps = 28/557 (5%)

Query: 23  AALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEKQATTATG---CPLLIRCKNFQI 79
           A  GTL +T   + F     DP     +    IS +EK    + G   C + I CK+ + 
Sbjct: 122 AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRN 181

Query: 80  IQLIIPQERDCH-DVYISLIRLARPVKY-EELYCFSFNPMLDKEEREQGWVLIDLSEEYT 137
           ++L   QE      ++ +L + A P+   + L+ FS+           GW + D   EY 
Sbjct: 182 LRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPIN----GWKVYDPVSEYK 237

Query: 138 RMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKD 197
           R GLPN  W++S +N +Y  CD+YP  + VP S     +   + FR++ R PVLS+ + +
Sbjct: 238 RQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPE 297

Query: 198 NHASICRSSQPLSGFS-ARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKG 256
           + A+I R SQPL G +  RC EDE+ LQ I  AN  S  + + D R    A  N+  G G
Sbjct: 298 SQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGG 357

Query: 257 YENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWLRHIK 314
           YE+E  Y N +  F+ I NIHVMR SL+K+ E+     PS+ +  W   ++ + WL +I+
Sbjct: 358 YESESAYPNAELVFLEIHNIHVMRESLRKLKEIVY---PSIDEARWLSNVDGTHWLEYIR 414

Query: 315 AIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDW 374
            ++   + IA  +     SV+VHCSDGWDRTAQ+ S+A L+LD +YRT+KGF  L+EK+W
Sbjct: 415 MLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEW 474

Query: 375 ISFGHKFNHR--YGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIY 432
           ISFGH+F  R  +GN +    + SP+  QF++CVWQ+  QFP AFEFNE FLI I  H+Y
Sbjct: 475 ISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLY 534

Query: 433 SCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHLPTTP 492
           SC FG FLCN +++R +  +  +T SLW+++     ++ NP F       +  +  P   
Sbjct: 535 SCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFF----VNYENHVLYPVAS 590

Query: 493 CNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEERLEKIQKVQLNC 552
            + + + W   Y R+   M+P+  +   L  +     +L++ +E L+      ++V    
Sbjct: 591 LSHL-ELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQ------REVATRA 643

Query: 553 TKVKSKQSEPSKHSGFS 569
               S++     HS  S
Sbjct: 644 VSSSSERGSSPSHSATS 660


>gi|217272865 myotubularin related protein 4 [Homo sapiens]
          Length = 1195

 Score =  285 bits (728), Expect = 1e-76
 Identities = 171/461 (37%), Positives = 252/461 (54%), Gaps = 56/461 (12%)

Query: 70  LLIRCKNFQIIQLIIPQERDCHDVYISLIRL-ARPVKYEELYCFSFNPM-LDKEEREQGW 127
           L I CK+ ++++      + C +    L R  ARP K E+L+ F+++   L   E +Q  
Sbjct: 87  LHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHT 146

Query: 128 VLIDLSE--------EYTRMGLP-NHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVG 178
            L    E        E  RMG    + W++S +N +Y++C SYP +L VP   T   +  
Sbjct: 147 HLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELEN 206

Query: 179 SSKFRSRRRFPVLSYYYKDNHASICRSSQP-LSGFSARCLEDEQMLQAIRKA---NPGS- 233
            + FRS +R PV+ Y +  N A+I R SQP +S +  R  +DE ++ +I KA   +PG+ 
Sbjct: 207 VASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTR 266

Query: 234 -------------------DF------------------VYVVDTRPKLNAMANRAAGKG 256
                              DF                  + ++D R    A+ANRA G G
Sbjct: 267 ATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGG 326

Query: 257 YENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAI 316
            E E+ Y N +  F+G+ NIH +RNS Q +  VC  + P  S++L  LE++ WL+H+  +
Sbjct: 327 CECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCS-QMPDPSNWLSALESTKWLQHLSVM 385

Query: 317 MDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWIS 376
           + A + +A  V  EG  VLVHCSDGWDRT Q+ ++A +LLDP+YRTL+GF VL+E DW+ 
Sbjct: 386 LKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLD 445

Query: 377 FGHKFNHRYGNLDG--DPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSC 434
           FGHKF  R G+ +   D  E  PV  Q+++ V QL++QFPC FEFNE FL+ +  H YSC
Sbjct: 446 FGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSC 505

Query: 435 QFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLF 475
            +G FL N+  ER +  I +RT S+WA L     ++ N L+
Sbjct: 506 LYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLY 546


>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
          Length = 1161

 Score =  281 bits (718), Expect = 2e-75
 Identities = 174/496 (35%), Positives = 255/496 (51%), Gaps = 67/496 (13%)

Query: 70  LLIRCKNFQIIQLIIPQERDCHDVYISLIRLARP-VKYEELYCFSFNPMLDK---EEREQ 125
           L + CK+ ++I+        C +    L    RP  K E+L+ F+++    +    E+EQ
Sbjct: 87  LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146

Query: 126 GWVLIDLSEEYT--------RMGLP-NHYWQLSDVNRDYRVCDSYPTELYVPKSATAHII 176
              L    E  T        RMG   N+ W++S++N  Y++C SYP EL VP   T   +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206

Query: 177 VGSSKFRSRRRFPVLSYYYKDNHASICRSSQP-LSGFSARCLEDEQMLQAIRKA------ 229
              S FRS +R P + Y ++ N A I R  QP +S +  R  +DE ++Q++ KA      
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266

Query: 230 ---------NPGSDF------------------------------VYVVDTRPKLNAMAN 250
                    N   DF                              + ++D R    A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326

Query: 251 RAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWL 310
           RA G G E  + Y N +  F+G+ NIH +R S Q +  +C  + P   ++L  LE++ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWL 385

Query: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
            H+  ++ + + +  AV ++   VLVHCSDGWDRT Q+ ++A LLLDP+YRT++GF VL+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445

Query: 371 EKDWISFGHKFNHR--YGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
           E +W+ FGHKF  R  +G    D  E  PV  Q+++CV QL  QFPC+FEFNE FL+ + 
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505

Query: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
            H YSC FG FLCN+ KER E   QERT S+W+ L      + N L+    SQ++  L+ 
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLY---SSQSEAVLYP 562

Query: 489 PTTPCNFMYKFWSGMY 504
                N M   WS +Y
Sbjct: 563 VCHVRNLM--LWSAVY 576


>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
          Length = 1170

 Score =  281 bits (718), Expect = 2e-75
 Identities = 174/496 (35%), Positives = 255/496 (51%), Gaps = 67/496 (13%)

Query: 70  LLIRCKNFQIIQLIIPQERDCHDVYISLIRLARP-VKYEELYCFSFNPMLDK---EEREQ 125
           L + CK+ ++I+        C +    L    RP  K E+L+ F+++    +    E+EQ
Sbjct: 87  LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146

Query: 126 GWVLIDLSEEYT--------RMGLP-NHYWQLSDVNRDYRVCDSYPTELYVPKSATAHII 176
              L    E  T        RMG   N+ W++S++N  Y++C SYP EL VP   T   +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206

Query: 177 VGSSKFRSRRRFPVLSYYYKDNHASICRSSQP-LSGFSARCLEDEQMLQAIRKA------ 229
              S FRS +R P + Y ++ N A I R  QP +S +  R  +DE ++Q++ KA      
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266

Query: 230 ---------NPGSDF------------------------------VYVVDTRPKLNAMAN 250
                    N   DF                              + ++D R    A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326

Query: 251 RAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWL 310
           RA G G E  + Y N +  F+G+ NIH +R S Q +  +C  + P   ++L  LE++ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWL 385

Query: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
            H+  ++ + + +  AV ++   VLVHCSDGWDRT Q+ ++A LLLDP+YRT++GF VL+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445

Query: 371 EKDWISFGHKFNHR--YGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
           E +W+ FGHKF  R  +G    D  E  PV  Q+++CV QL  QFPC+FEFNE FL+ + 
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505

Query: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
            H YSC FG FLCN+ KER E   QERT S+W+ L      + N L+    SQ++  L+ 
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLY---SSQSEAVLYP 562

Query: 489 PTTPCNFMYKFWSGMY 504
                N M   WS +Y
Sbjct: 563 VCHVRNLM--LWSAVY 576


>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
          Length = 1198

 Score =  281 bits (718), Expect = 2e-75
 Identities = 174/496 (35%), Positives = 255/496 (51%), Gaps = 67/496 (13%)

Query: 70  LLIRCKNFQIIQLIIPQERDCHDVYISLIRLARP-VKYEELYCFSFNPMLDK---EEREQ 125
           L + CK+ ++I+        C +    L    RP  K E+L+ F+++    +    E+EQ
Sbjct: 87  LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146

Query: 126 GWVLIDLSEEYT--------RMGLP-NHYWQLSDVNRDYRVCDSYPTELYVPKSATAHII 176
              L    E  T        RMG   N+ W++S++N  Y++C SYP EL VP   T   +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206

Query: 177 VGSSKFRSRRRFPVLSYYYKDNHASICRSSQP-LSGFSARCLEDEQMLQAIRKA------ 229
              S FRS +R P + Y ++ N A I R  QP +S +  R  +DE ++Q++ KA      
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266

Query: 230 ---------NPGSDF------------------------------VYVVDTRPKLNAMAN 250
                    N   DF                              + ++D R    A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326

Query: 251 RAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWL 310
           RA G G E  + Y N +  F+G+ NIH +R S Q +  +C  + P   ++L  LE++ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWL 385

Query: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
            H+  ++ + + +  AV ++   VLVHCSDGWDRT Q+ ++A LLLDP+YRT++GF VL+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445

Query: 371 EKDWISFGHKFNHR--YGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
           E +W+ FGHKF  R  +G    D  E  PV  Q+++CV QL  QFPC+FEFNE FL+ + 
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505

Query: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
            H YSC FG FLCN+ KER E   QERT S+W+ L      + N L+    SQ++  L+ 
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLY---SSQSEAVLYP 562

Query: 489 PTTPCNFMYKFWSGMY 504
                N M   WS +Y
Sbjct: 563 VCHVRNLM--LWSAVY 576


>gi|239735519 SET binding factor 1 [Homo sapiens]
          Length = 1893

 Score =  139 bits (350), Expect = 8e-33
 Identities = 81/214 (37%), Positives = 122/214 (57%), Gaps = 7/214 (3%)

Query: 242  RPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVC----ELKSPSM 297
            R  L  + ++A  KG  + D     +   I +     ++ S +K+L+ C        PS 
Sbjct: 1349 RAALYILGDKAQLKGVRS-DPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPAAEPSP 1407

Query: 298  SDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLD 357
            + FL  LE+S WL  I  ++   + + + + + G+SVLV   DGWD T QV S+  LL D
Sbjct: 1408 ASFLRSLEDSEWLIQIHKLLQVSVLVVELL-DSGSSVLVGLEDGWDITTQVVSLVQLLSD 1466

Query: 358  PHYRTLKGFMVLIEKDWISFGHKFNHRYGN-LDGDPKEISPVIDQFIECVWQLMEQFPCA 416
            P YRTL+GF +L+EK+W+SFGH+F+HR  + L G     +PV  QF++CV Q+  QFP  
Sbjct: 1467 PFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQVHLQFPME 1526

Query: 417  FEFNERFLIHIQHHIYSCQFGNFLCNSQKERREL 450
            FEF++ +L  + +H  S +F  FL +S  ER EL
Sbjct: 1527 FEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIEL 1560



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 28/125 (22%)

Query: 135  EYTRMGL----------PNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRS 184
            +Y R+GL           +  +++S VNR Y +C SYP  L VP+S   + +   S+   
Sbjct: 1129 DYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYR 1188

Query: 185  RRRFPVLSYYYKDNHASICRS---------------SQPLSGFS---ARCLEDEQMLQAI 226
            + RFPV+ +    + A + RS               + P  G S   +  LE E+ LQA+
Sbjct: 1189 QNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAV 1248

Query: 227  RKANP 231
              + P
Sbjct: 1249 VSSMP 1253


>gi|29788755 SET binding factor 2 [Homo sapiens]
          Length = 1849

 Score =  132 bits (333), Expect = 8e-31
 Identities = 110/407 (27%), Positives = 172/407 (42%), Gaps = 93/407 (22%)

Query: 135  EYTRMGLPN----------HYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRS 184
            +Y R+GL             Y++++  NR Y +C SYP  L VP++     +   ++   
Sbjct: 1117 DYQRLGLGTISGSSSRSRPEYFRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYR 1176

Query: 185  RRRFPVLSYYYKDNHASICRS-------------------SQPLSGF-SARCLEDEQMLQ 224
              R PV+ +    +   + RS                   + P S   S+  +E E+ LQ
Sbjct: 1177 HNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQ 1236

Query: 225  AIRKA---------------------NPG-----SDFVYVVDTRPKLNAMANRAAGKGYE 258
            A+  A                     +PG          ++ +      +  R AGK + 
Sbjct: 1237 ALLNAVSVHQKLRGNSTLTVRPAFALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHS 1296

Query: 259  ------------------------NEDNYSNIKFQF--------IGIENIHVMRNSLQKM 286
                                     +    N K +F        +    I  ++ S +K+
Sbjct: 1297 ASFSNSSYLQNQLLKRQAALYIFGEKSQLRNFKVEFALNCEFVPVEFHEIRQVKASFKKL 1356

Query: 287  LEVC---ELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWD 343
            +  C    + + S   FL  L +S W   +  IM   + +++ V E G+SVLV   +GWD
Sbjct: 1357 MRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSE-VLENGSSVLVCLEEGWD 1415

Query: 344  RTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYG-NLDGDPKEISPVIDQF 402
             TAQV S+  LL DP YRTL+GF +L+EK+W+SFGHKF+ R    L+      +PV  QF
Sbjct: 1416 ITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKFSQRSSLTLNCQGSGFAPVFLQF 1475

Query: 403  IECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRE 449
            ++CV Q+  Q+P  FEFN  +L  +  H  S +F  FL +S  ER E
Sbjct: 1476 LDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLE 1522


>gi|124028527 myotubularin related protein 10 [Homo sapiens]
          Length = 777

 Score =  115 bits (288), Expect = 1e-25
 Identities = 85/317 (26%), Positives = 143/317 (45%), Gaps = 31/317 (9%)

Query: 131 DLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPV 190
           D   E  R G     W++  +N  Y +    P  + VP S     +   S     RR P+
Sbjct: 226 DWDREIKRTGASG--WRVCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPL 283

Query: 191 LSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMAN 250
             + +  N +++ R +        R + D+++  AI K++P    VY  D    L     
Sbjct: 284 WCWSH-SNGSALVRMALIKDVLQQRKI-DQRICNAITKSHPQRSDVYKSDLDKTL----- 336

Query: 251 RAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWL 310
                      N   ++  F+ +           K L V E    +   +L  LEN+ WL
Sbjct: 337 ----------PNIQEVQAAFVKL-----------KQLCVNEPFEETEEKWLSSLENTRWL 375

Query: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
            +++A +     +   +  +  SV++   +G D +  V S+  ++LDP++RT+ GF  LI
Sbjct: 376 EYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLI 435

Query: 371 EKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHH 430
           +K+W+  G++F  R  +L    KE SP+   F++  WQL+EQ+P AFEF+E +L  +   
Sbjct: 436 QKEWVMAGYQFLDRCNHLKRSEKE-SPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDS 494

Query: 431 IYSCQFGNFLCNSQKER 447
                FG FL NS  +R
Sbjct: 495 TRISLFGTFLFNSPHQR 511


>gi|94721263 myotubularin related protein 12 [Homo sapiens]
          Length = 747

 Score =  108 bits (271), Expect = 1e-23
 Identities = 97/392 (24%), Positives = 168/392 (42%), Gaps = 44/392 (11%)

Query: 70  LLIRCKNFQIIQLII--PQERDCHDVYISLIRLAR-PVKYEELYCFSF------NPMLDK 120
           L+I CK+ ++ Q  +   +E +   +   +I   + P   + L+ FS+      N + D 
Sbjct: 139 LIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDP 198

Query: 121 EEREQGWVLIDLSEEYT---RMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIV 177
           +      V+ D  +++         N  ++   VN  Y+VC+  P    VP       + 
Sbjct: 199 KNHT---VMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLPAYFVVPTPLPEENV- 254

Query: 178 GSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVY 237
              +F+     P+  +         C +   L   SA   E +  +  I+K+    D +Y
Sbjct: 255 --QRFQGHG-IPIWCWS--------CHNGSALLKMSALPKEQDDGILQIQKSF--LDGIY 301

Query: 238 VVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSM 297
               RP    +         + ED  SN    F+ ++ I    +  +++  +        
Sbjct: 302 KTIHRPPYEIV---------KTEDLSSN----FLSLQEIQTAYSKFKQLFLIDNSTEFWD 348

Query: 298 SDFLWG--LENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLL 355
           +D  W   LE+S WL  I+  +   I I + +  +  +VL+   +  D    + S+  L+
Sbjct: 349 TDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLM 408

Query: 356 LDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPC 415
           +DPH RT  GF  LI+K+W+  GH F  R  +L  + KE  PV   F++CVWQL+ Q P 
Sbjct: 409 MDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPP 468

Query: 416 AFEFNERFLIHIQHHIYSCQFGNFLCNSQKER 447
           AFEF E +L  +   +Y   F  F  NS  ++
Sbjct: 469 AFEFTETYLTVLSDSLYIPIFSTFFFNSPHQK 500


>gi|224994251 myotubularin related protein 11 isoform a [Homo
           sapiens]
          Length = 709

 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 81/316 (25%), Positives = 141/316 (44%), Gaps = 39/316 (12%)

Query: 146 WQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRS 205
           W++S VN  + V  S P   +VP       +  +     + R P LS+++    + + R 
Sbjct: 214 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHPGG-SDLLRC 272

Query: 206 SQPLSGFSARCLEDEQMLQAIR-KANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYS 264
                GF      +++ ++A+      G   V +VDT  +L ++A+              
Sbjct: 273 G----GFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLAD-------------- 314

Query: 265 NIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWLRHIKAIMDAGIF 322
                   ++  H+   +L      C L   S+++  W   LE + WL +++A +     
Sbjct: 315 --------VQLAHLRLRAL------C-LPDSSVAEDKWLSALEGTRWLDYVRACLRKASD 359

Query: 323 IAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFN 382
           I+  V+    SV++      D    + S+  LL  P  RTL GF  L++++W++ GH F 
Sbjct: 360 ISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFL 419

Query: 383 HRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCN 442
            R G       E +PV   F++CVWQL++QFP  FEF+E FL+ +   +       FL N
Sbjct: 420 TRLGGTGA--SEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRN 477

Query: 443 SQKERRELKIQERTYS 458
           +  ER +   Q  +Y+
Sbjct: 478 TPWERGKQSGQLNSYT 493


>gi|89111941 myotubularin related protein 11 isoform b [Homo
           sapiens]
          Length = 640

 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 81/316 (25%), Positives = 141/316 (44%), Gaps = 39/316 (12%)

Query: 146 WQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRS 205
           W++S VN  + V  S P   +VP       +  +     + R P LS+++    + + R 
Sbjct: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHPGG-SDLLRC 200

Query: 206 SQPLSGFSARCLEDEQMLQAIR-KANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYS 264
                GF      +++ ++A+      G   V +VDT  +L ++A+              
Sbjct: 201 G----GFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLAD-------------- 242

Query: 265 NIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWLRHIKAIMDAGIF 322
                   ++  H+   +L      C L   S+++  W   LE + WL +++A +     
Sbjct: 243 --------VQLAHLRLRAL------C-LPDSSVAEDKWLSALEGTRWLDYVRACLRKASD 287

Query: 323 IAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFN 382
           I+  V+    SV++      D    + S+  LL  P  RTL GF  L++++W++ GH F 
Sbjct: 288 ISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFL 347

Query: 383 HRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCN 442
            R G       E +PV   F++CVWQL++QFP  FEF+E FL+ +   +       FL N
Sbjct: 348 TRLGGTGA--SEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRN 405

Query: 443 SQKERRELKIQERTYS 458
           +  ER +   Q  +Y+
Sbjct: 406 TPWERGKQSGQLNSYT 421


>gi|239758162 PREDICTED: heterogeneous nuclear ribonucleoprotein
           C-like [Homo sapiens]
          Length = 293

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 11/112 (9%)

Query: 519 DYLMAVKEETQQLEEELEALEERLEKIQKVQL-NCTKVKSKQSEPSKHSGFSTSDNSIAN 577
           D L A+K+E  Q+++++++L E LEKI+K       +VK+ +SE  + S  S  D +   
Sbjct: 178 DDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKT--- 234

Query: 578 TPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVED 629
                  ++K           E+  L+   DN    D  L    D E G E+
Sbjct: 235 -------HVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEE 279


>gi|239752620 PREDICTED: similar to heterogeneous nuclear
           ribonucleoprotein C-like [Homo sapiens]
          Length = 293

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 11/112 (9%)

Query: 519 DYLMAVKEETQQLEEELEALEERLEKIQKVQL-NCTKVKSKQSEPSKHSGFSTSDNSIAN 577
           D L A+K+E  Q+++++++L E LEKI+K       +VK+ +SE  + S  S  D +   
Sbjct: 178 DDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKT--- 234

Query: 578 TPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVED 629
                  ++K           E+  L+   DN    D  L    D E G E+
Sbjct: 235 -------HVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEE 279


>gi|226052117 heterogeneous nuclear ribonucleoprotein C-like [Homo
           sapiens]
          Length = 293

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 11/112 (9%)

Query: 519 DYLMAVKEETQQLEEELEALEERLEKIQKVQL-NCTKVKSKQSEPSKHSGFSTSDNSIAN 577
           D L A+K+E  Q+++++++L E LEKI+K       +VK+ +SE  + S  S  D +   
Sbjct: 178 DDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKT--- 234

Query: 578 TPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVED 629
                  ++K           E+  L+   DN    D  L    D E G E+
Sbjct: 235 -------HVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEE 279


>gi|117190254 heterogeneous nuclear ribonucleoprotein C isoform b
           [Homo sapiens]
          Length = 293

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 11/112 (9%)

Query: 519 DYLMAVKEETQQLEEELEALEERLEKIQKVQ-LNCTKVKSKQSEPSKHSGFSTSDNSIAN 577
           D L A+K+E  Q+++++++L E LEKI+K Q     ++K+ +SE  + S     D +   
Sbjct: 178 DDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVKKDET--- 234

Query: 578 TPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVED 629
                  N+K           E+  L+   DN    D  L    D E   E+
Sbjct: 235 -------NVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEE 279


>gi|117190192 heterogeneous nuclear ribonucleoprotein C isoform a
           [Homo sapiens]
          Length = 306

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 11/112 (9%)

Query: 519 DYLMAVKEETQQLEEELEALEERLEKIQKVQ-LNCTKVKSKQSEPSKHSGFSTSDNSIAN 577
           D L A+K+E  Q+++++++L E LEKI+K Q     ++K+ +SE  + S     D +   
Sbjct: 191 DDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVKKDET--- 247

Query: 578 TPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVED 629
                  N+K           E+  L+   DN    D  L    D E   E+
Sbjct: 248 -------NVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEE 292


>gi|117190174 heterogeneous nuclear ribonucleoprotein C isoform b
           [Homo sapiens]
          Length = 293

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 11/112 (9%)

Query: 519 DYLMAVKEETQQLEEELEALEERLEKIQKVQ-LNCTKVKSKQSEPSKHSGFSTSDNSIAN 577
           D L A+K+E  Q+++++++L E LEKI+K Q     ++K+ +SE  + S     D +   
Sbjct: 178 DDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVKKDET--- 234

Query: 578 TPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVED 629
                  N+K           E+  L+   DN    D  L    D E   E+
Sbjct: 235 -------NVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEE 279


>gi|117189975 heterogeneous nuclear ribonucleoprotein C isoform a
           [Homo sapiens]
          Length = 306

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 11/112 (9%)

Query: 519 DYLMAVKEETQQLEEELEALEERLEKIQKVQ-LNCTKVKSKQSEPSKHSGFSTSDNSIAN 577
           D L A+K+E  Q+++++++L E LEKI+K Q     ++K+ +SE  + S     D +   
Sbjct: 191 DDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVKKDET--- 247

Query: 578 TPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVED 629
                  N+K           E+  L+   DN    D  L    D E   E+
Sbjct: 248 -------NVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEE 292


>gi|211971067 heterogeneous nuclear ribonucleoprotein C-like [Homo
           sapiens]
          Length = 293

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 33/117 (28%), Positives = 58/117 (49%), Gaps = 8/117 (6%)

Query: 519 DYLMAVKEETQQLEEELEALEERLEKIQKVQLNC-TKVKSKQSEPSKHSGFSTSDNSIAN 577
           D L A+K+E  Q+++++++L E LEKI+K Q     +VK+ +SE  + S     D +   
Sbjct: 178 DDLQAIKQELTQIKQKVDSLLENLEKIEKEQSKQEVEVKNAKSEEEQSSSSMKKDETHVK 237

Query: 578 TPQDYSGNMKSFPSRSPSQGDE-----DSALILTQDNLKSSDPDLSANSDQESGVED 629
              +  G   S     P   D+     D+ L L ++N K ++ +   N D  +G +D
Sbjct: 238 MESE-GGAEDSAEEGDPLDDDDNEDQGDNQLHLIKNNEKDAE-EGEDNRDSTNGQDD 292


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 1/100 (1%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S  S SD+S ++   D S +  S  S   S   ++S    + ++  SSD  
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948

Query: 617 LSANSDQESGVEDLSCRSPSGGEH-APSEDSGKDRDSDEA 655
            S+NS   S   D S  S S   + + S DS    DS ++
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 1/99 (1%)

Query: 557  SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
            S  S  S  S  S S +S ++   D S +  S  S   S   + S    + D+  SSD  
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013

Query: 617  LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
             S+NS   S   D S  S    + + S DS    DS ++
Sbjct: 1014 DSSNSSDSSNSSD-SSNSSDSSDSSDSSDSSDSSDSSDS 1051



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 1/100 (1%)

Query: 557  SKQSEPSKHSGFS-TSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDP 615
            S  S+ S  S  S +SD+S ++   D S +  S  S   S   + S    + D+ +SSD 
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087

Query: 616  DLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
              S+NS   S   D S  S S      S+ S     SD +
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127



 Score = 37.0 bits (84), Expect = 0.058
 Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 557 SKQSEPSKHSGFS-TSDNSIANTPQDYSGNMKSFPSRSPSQGDE-DSALILTQDNLKSSD 614
           S  S+ S  S  S +SD+S ++  +  S   +S  S S S+ D  DS    + DN  SSD
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658

Query: 615 PDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
              S+NS   S   D S  S S  + + S DS    DS  +
Sbjct: 659 SSNSSNSSDSSDSSD-SSDSSSSSDSSNSSDSSDSSDSSNS 698



 Score = 37.0 bits (84), Expect = 0.058
 Identities = 27/103 (26%), Positives = 43/103 (41%)

Query: 553 TKVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKS 612
           +K +S  S+    S  S S++S ++   D S +  S  S   S   + S    + D+  S
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686

Query: 613 SDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
           SD   S++S   S   D S  S S    +    +    DSD +
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729



 Score = 37.0 bits (84), Expect = 0.058
 Identities = 27/99 (27%), Positives = 41/99 (41%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S  S  S  S S +S +++    S +       S S    DS+     D+  SSD  
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S +SD +S     S  S +  + + S DS    DS ++
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758



 Score = 37.0 bits (84), Expect = 0.058
 Identities = 33/101 (32%), Positives = 40/101 (39%), Gaps = 3/101 (2%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S  S S NS  ++    S N  S  S S    D DS+      N  SSD D
Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDSSN-SSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727

Query: 617 LSANSD--QESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S +SD    S   D S  S S      S+ S     SD +
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768



 Score = 36.2 bits (82), Expect = 0.099
 Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 5/92 (5%)

Query: 566 SGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSD--- 622
           S  S SD+S ++   D S +  S  S S S  D DS+   + D+  S   D S +SD   
Sbjct: 547 SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606

Query: 623 --QESGVEDLSCRSPSGGEHAPSEDSGKDRDS 652
               S   D S  S S  + + SE    D DS
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638



 Score = 36.2 bits (82), Expect = 0.099
 Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 4/99 (4%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  +E S  S  S S NS  +   D S +  S  S + S   E S    + DN  SSD  
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN---SSDNSNSSDSS 939

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S++S   S   + S  S +  + + S DS     SD +
Sbjct: 940 NSSDSSDSSDSSN-SSDSSNSSDSSNSSDSSDSNSSDSS 977



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 2/103 (1%)

Query: 554 KVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSS 613
           K KS  S+ S  S  S S +S  ++  D S +  S  S S      DS+   + D+  SS
Sbjct: 544 KGKSDSSD-SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSS 602

Query: 614 D-PDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
           D  D S +SD     +    +S S    + S DS    DS ++
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS 645



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 7/99 (7%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S  S S NS  +     S +     + S S    DS+     D+  SSD D
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS-----DSSDSSDSD 819

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S +SD  +  +  S  S +  + + S DS    DSD +
Sbjct: 820 SSNSSDSSNSSD--SSDSSNSSDSSDSSDSSDGSDSDSS 856



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 6/104 (5%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S     + SD+S ++   D S +  S  S   S  +E S    + D+  SSD D
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904

Query: 617 L-----SANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
                 S++S   S   D S  S +  +++ S DS    DS ++
Sbjct: 905 SSDSSNSSDSSDSSNSSD-SSESSNSSDNSNSSDSSNSSDSSDS 947



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 1/99 (1%)

Query: 557  SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
            S  S+ S+ S  S + NS  ++    S +     + S S    DS+      +  SSD  
Sbjct: 918  SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977

Query: 617  LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
             S+NS   S   D S  S S  + + S DS    DS ++
Sbjct: 978  DSSNSSDSSDSSDSSDSSDS-SDSSNSSDSSDSSDSSDS 1015



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 2/99 (2%)

Query: 557  SKQSEPSKHSGFS-TSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDP 615
            S  S+ S  S  S +SD+S ++   D S +  S  S   S  +E S    + D+  SS+ 
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249

Query: 616  -DLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSD 653
             D S +SD      D +  S S  +     ++G D DSD
Sbjct: 1250 SDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 27/99 (27%), Positives = 39/99 (39%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S  S  S  S+  +  +++    S + KS    S S    DS+   + D+  +SD  
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S+NS   S   D S  S S      S  S     SD +
Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 5/99 (5%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S  S  S  S+  N  +N+      +  S    S S    DS+     D+  SSD  
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS-----DSSNSSDSS 924

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S+NS   S   D S  S S      S  S     SD +
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 3/99 (3%)

Query: 557  SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
            S  S+ S  S  S S +S  ++    S N     + S S    DS+   + D+  SSD  
Sbjct: 995  SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD--SSDSSDSSDSS 1052

Query: 617  LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
             S+NS   S   D S  S S  + + S DS +  DS ++
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDS-SDSSDSSDSSESSDSSDS 1090



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 3/101 (2%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S  S +S  S SD+S ++   + S +  S  S S    D  ++     D+  SSD  
Sbjct: 677 SSSSSDSSNSSDS-SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735

Query: 617 LSANSDQESGVEDLSCRSPS--GGEHAPSEDSGKDRDSDEA 655
            S+NS   S   D S  S S    + + S DS    DS ++
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 4/101 (3%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S  S S +S  +   D S +  S  S S S    DS+   + ++  SSD  
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD--SSNSSDSSDSS 747

Query: 617 LSANSDQESGVEDLSCRSPS--GGEHAPSEDSGKDRDSDEA 655
            S+NS   S   D S  S S    + + S DS    DS+++
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS 788



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 3/99 (3%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S      +SD+S +N+    S N       S S    DS+   + ++  SSD  
Sbjct: 702 SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS--DSSNSSDSSDSS 759

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S+NS   S   D S  S S    + S DS    DS ++
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNS-SDSNDSSNSSDSSDS 797



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 6/99 (6%)

Query: 557  SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
            S  S+ S  S  S S +S  ++    S N       S S    DS+     D+  SSD  
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS-----DSSDSSDSS 1118

Query: 617  LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
             S+NS   S   D S  S S    + S DS +  DS ++
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNS-SDSSDSSESSDSSDS 1156



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 2/99 (2%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S  + S NS  ++    S +  +    S S    DS    + D+  SSD  
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S+NS   S   D S  S S  + +   DS    DS ++
Sbjct: 834 DSSNSSDSSDSSDSSDGSDS--DSSNRSDSSNSSDSSDS 870



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 6/99 (6%)

Query: 557  SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
            S  S  S +S  S++ +  +N+      N       S S    DS+     D+  SSD  
Sbjct: 944  SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS-----DSSDSSDSS 998

Query: 617  LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
             S+NS   S   D S  S +  + + S DS    DS ++
Sbjct: 999  DSSNSSDSSDSSD-SSDSSNSSDSSNSSDSSNSSDSSDS 1036



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 5/104 (4%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S     S  S  ++SD+S  +   D S +  S  S   S   + S+   + ++  SSD  
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693

Query: 617 LSANSDQ-----ESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S+NS +     +S   D S  S S   ++   DS    DS ++
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 8/103 (7%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALIL----TQDNLKS 612
           S  S+ S  S  S S NS  ++    S N       S S    DS+       + D+  S
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782

Query: 613 SDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
           SD + S+NS   S     S  S      + S DS    DSD +
Sbjct: 783 SDSNDSSNSSDSSD----SSNSSDSSNSSDSSDSSDSSDSDSS 821



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 6/101 (5%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQG-DEDSALILTQDNLK-SSD 614
           S  S+ S     ++SD+S ++   D S +  S  S   S G D DS+      N   SSD
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869

Query: 615 PDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
              S+NS   S   D    S      + S DS    DSD +
Sbjct: 870 SSDSSNSSDSSDSSD----SNESSNSSDSSDSSNSSDSDSS 906



 Score = 33.9 bits (76), Expect = 0.49
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 2/100 (2%)

Query: 557  SKQSEPSKHSGFSTSDNSI-ANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDP 615
            S  S+ S+ S  S S NS  ++   D S +  S  S   S   + S    + D+  SSD 
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135

Query: 616  DLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
              S+NS   S   + S  S S  + + S DS    DS ++
Sbjct: 1136 SDSSNSSDSSDSSESSDSSDS-SDSSDSSDSSDSSDSSDS 1174



 Score = 33.9 bits (76), Expect = 0.49
 Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 6/99 (6%)

Query: 557  SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
            S  S+ S  S   +SD+S ++   D S + +S  S   S   + S    + D+  SSD  
Sbjct: 1121 SNSSDSSDSS--DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD---SSDSSDSSDSS 1175

Query: 617  LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
             S+NS   S   D S  S S  + + S DS    DS ++
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDS 1213



 Score = 33.5 bits (75), Expect = 0.64
 Identities = 25/99 (25%), Positives = 40/99 (40%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S   +SD+S ++   D S +  S  S   S    DS+   +  +   S  D
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S ++  +S     S  S +    + S DS    DS  +
Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680



 Score = 33.5 bits (75), Expect = 0.64
 Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 2/99 (2%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+    S  S SD+S +++  D S +  S  S +    D  ++   +  +  S   D
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S++SD  +  +  S  S      + S DS    DSD +
Sbjct: 677 SSSSSDSSNSSD--SSDSSDSSNSSESSDSSDSSDSDSS 713



 Score = 33.1 bits (74), Expect = 0.84
 Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 1/100 (1%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S  S S NS  ++    S +  S  S   S   + S    + D+  SSD  
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848

Query: 617 LSANSDQESGVEDL-SCRSPSGGEHAPSEDSGKDRDSDEA 655
             ++SD  +  +   S  S    + + S DS    DS+E+
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 1/103 (0%)

Query: 554 KVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSS 613
           K  S  S+ S  S  S S +S  +   D + +  S  S S S    DS    + ++  SS
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605

Query: 614 DP-DLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
           D  D S +SD     +  S  S S  + + S+      DS+ +
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 1/98 (1%)

Query: 557  SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
            S  S  S +S  S SD+S ++   D S +  S  S   S   + S    + D+  SSD  
Sbjct: 1171 SSDSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229

Query: 617  LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDE 654
             S  S   S   D S  S S      S+ S    DS++
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 4/103 (3%)

Query: 557 SKQSEPSKHSGFSTSDNSIA----NTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKS 612
           S  S+ S  +  S SD+S +    ++  D S +  S  S   S   + S    + D+   
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625

Query: 613 SDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
           S    S +SD +S  +     S    +++ S DS    +S ++
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 29/104 (27%), Positives = 38/104 (36%), Gaps = 5/104 (4%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S  S  S  S S +S  ++  D S +  S  S   S     S    + D+   SD D
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854

Query: 617 L-----SANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
                 S+NS   S   D S  S S      +E S     SD +
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 1/99 (1%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S  S   +S ++   D S +  S  S   S   + S    + ++  SSD  
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895

Query: 617 LSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S+NS  +S   D S  S S      S+ S     SD +
Sbjct: 896 DSSNS-SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS 933



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 2/101 (1%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           S  S+ S  S  S SD+S  +   + S +  S  S + S   + S    + ++  SSD  
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898

Query: 617 LSANSD--QESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S++SD    S   D S  S S      S  S     SD +
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSS 939



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 10/107 (9%)

Query: 557  SKQSEPSKHSGFS-TSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDP 615
            S  S+ S  S  S +SD+S ++   D S +  S  S   S   + S    + D+  SSD 
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243

Query: 616  DLSANSDQESGVEDLSCRSPSGGEHAPSED---------SGKDRDSD 653
              S+NS   S   D S  +    + + S+          S  D DS+
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 6/103 (5%)

Query: 557 SKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPD 616
           SK +E       S ++NS +N   + +GN  +  S S  +G  DS+   + D+  SSD  
Sbjct: 507 SKGAEDDDSDSTSDTNNSDSNGNGN-NGNDDNDKSDS-GKGKSDSSDSDSSDSSNSSDSS 564

Query: 617 LSANSD----QESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEA 655
            S++SD      S   D S    S    + S DS    DS ++
Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607


>gi|154816198 transcription elongation factor B polypeptide 3C-like
           [Homo sapiens]
          Length = 546

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 16/139 (11%)

Query: 521 LMAVKEETQQLEEELEALEERLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSD---NSIAN 577
           L   KEE  Q  E    L  RL   ++ +L     K + +  +K SG  T     NS+A 
Sbjct: 398 LQDFKEEKPQEHESWRELYLRLRDAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAK 457

Query: 578 TPQDYSGNM-KSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPS 636
           TP D S    KS  +  P  G+ + A            P  + +S   SG+ D    S S
Sbjct: 458 TPYDASRRQEKSAGAADPGNGEMEPA------------PKPAGSSQAPSGLGDGDGGSVS 505

Query: 637 GGEHAPSEDSGKDRDSDEA 655
           GG  +    +  D+   +A
Sbjct: 506 GGGSSNRHAAPADKTRKQA 524


>gi|156938279 transcription elongation factor B polypeptide 3C [Homo
           sapiens]
          Length = 546

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 16/139 (11%)

Query: 521 LMAVKEETQQLEEELEALEERLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSD---NSIAN 577
           L   KEE  Q  E    L  RL   ++ +L     K + +  +K SG  T     NS+A 
Sbjct: 398 LQDFKEEKPQEHESWRELYLRLRDAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAK 457

Query: 578 TPQDYSGNM-KSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPS 636
           TP D S    KS  +  P  G+ + A            P  + +S   SG+ D    S S
Sbjct: 458 TPYDASRRQEKSAGAADPGNGEMEPA------------PKPAGSSQAPSGLGDGDGGSVS 505

Query: 637 GGEHAPSEDSGKDRDSDEA 655
           GG  +    +  D+   +A
Sbjct: 506 GGGSSNRHAAPADKTRKQA 524


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,451,413
Number of Sequences: 37866
Number of extensions: 1223911
Number of successful extensions: 6024
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 5692
Number of HSP's gapped (non-prelim): 358
length of query: 660
length of database: 18,247,518
effective HSP length: 109
effective length of query: 551
effective length of database: 14,120,124
effective search space: 7780188324
effective search space used: 7780188324
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.