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Search of human proteins with 225543438
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225543438 complement component 2 isoform 2 preproprotein
[Homo sapiens]
(620 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225543438 complement component 2 isoform 2 preproprotein [Hom... 1270 0.0
gi|14550407 complement component 2 isoform 1 preproprotein [Homo... 1238 0.0
gi|67782358 complement factor B preproprotein [Homo sapiens] 402 e-112
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 83 7e-16
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 83 7e-16
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 82 2e-15
gi|148231605 ovochymase 2 [Homo sapiens] 82 2e-15
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 78 2e-14
gi|13994276 marapsin [Homo sapiens] 76 8e-14
gi|33186882 testis serine protease 2 [Homo sapiens] 76 1e-13
gi|4506115 protein C [Homo sapiens] 75 2e-13
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 75 2e-13
gi|32698940 transmembrane protease, serine 12 [Homo sapiens] 75 2e-13
gi|4502495 complement component 1, s subcomponent precursor [Hom... 74 3e-13
gi|41393602 complement component 1, s subcomponent precursor [Ho... 74 3e-13
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 74 3e-13
gi|4506153 prostasin preproprotein [Homo sapiens] 74 4e-13
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 74 5e-13
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 74 5e-13
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 74 5e-13
gi|148806900 epidermis-specific serine protease-like protein [Ho... 74 5e-13
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 73 7e-13
gi|4503627 coagulation factor XI precursor [Homo sapiens] 72 2e-12
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 71 3e-12
gi|117956391 protease, serine, 33 [Homo sapiens] 71 3e-12
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 70 4e-12
gi|34098976 marapsin 2 [Homo sapiens] 70 6e-12
gi|33695155 hepsin [Homo sapiens] 70 8e-12
gi|4504481 hepsin [Homo sapiens] 70 8e-12
gi|7019563 testes-specific protease 50 [Homo sapiens] 70 8e-12
>gi|225543438 complement component 2 isoform 2 preproprotein [Homo
sapiens]
Length = 620
Score = 1270 bits (3286), Expect = 0.0
Identities = 620/620 (100%), Positives = 620/620 (100%)
Query: 1 MGPLMVLFCLLFLYPAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQ 60
MGPLMVLFCLLFLYPAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQ
Sbjct: 1 MGPLMVLFCLLFLYPAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQ 60
Query: 61 GNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGH 120
GNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGH
Sbjct: 61 GNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGH 120
Query: 121 LNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDN 180
LNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDN
Sbjct: 121 LNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDN 180
Query: 181 SRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAII 240
SRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAII
Sbjct: 181 SRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAII 240
Query: 241 LLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDG 300
LLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDG
Sbjct: 241 LLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDG 300
Query: 301 ERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETC 360
ERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETC
Sbjct: 301 ERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETC 360
Query: 361 RGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQ 420
RGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQ
Sbjct: 361 RGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQ 420
Query: 421 GILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQS 480
GILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQS
Sbjct: 421 GILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQS 480
Query: 481 VPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDE 540
VPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDE
Sbjct: 481 VPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDE 540
Query: 541 SPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINL 600
SPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINL
Sbjct: 541 SPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINL 600
Query: 601 FRMQPWLRQHLGDVLNFLPL 620
FRMQPWLRQHLGDVLNFLPL
Sbjct: 601 FRMQPWLRQHLGDVLNFLPL 620
>gi|14550407 complement component 2 isoform 1 preproprotein [Homo
sapiens]
Length = 752
Score = 1238 bits (3204), Expect = 0.0
Identities = 605/605 (100%), Positives = 605/605 (100%)
Query: 16 AGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQP 75
AGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQP
Sbjct: 148 AGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQP 207
Query: 76 YSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSE 135
YSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSE
Sbjct: 208 YSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSE 267
Query: 136 NDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVISSLENAN 195
NDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVISSLENAN
Sbjct: 268 NDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVISSLENAN 327
Query: 196 YKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSPKT 255
YKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSPKT
Sbjct: 328 YKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSPKT 387
Query: 256 AVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQDTKALHQ 315
AVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQDTKALHQ
Sbjct: 388 AVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQDTKALHQ 447
Query: 316 VFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAH 375
VFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAH
Sbjct: 448 VFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAH 507
Query: 376 CFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKL 435
CFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKL
Sbjct: 508 CFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKL 567
Query: 436 AQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNI 495
AQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNI
Sbjct: 568 AQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNI 627
Query: 496 NLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLER 555
NLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLER
Sbjct: 628 NLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLER 687
Query: 556 RFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLGDVL 615
RFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLGDVL
Sbjct: 688 RFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLGDVL 747
Query: 616 NFLPL 620
NFLPL
Sbjct: 748 NFLPL 752
Score = 49.3 bits (116), Expect = 1e-05
Identities = 31/71 (43%), Positives = 37/71 (52%), Gaps = 7/71 (9%)
Query: 1 MGPLMVLFCLLFLYP-----AGHCP-NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGS 54
MGPLMVLFCLLFLYP A CP N IS G + G + Y C L + +
Sbjct: 1 MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPA 60
Query: 55 SERECQGNGVW 65
S R C+ +G W
Sbjct: 61 S-RLCKSSGQW 70
Score = 38.1 bits (87), Expect = 0.024
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 38 GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 72
G V + C +L GS R+C+ NG+W G +C
Sbjct: 110 GGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVC 144
>gi|67782358 complement factor B preproprotein [Homo sapiens]
Length = 764
Score = 402 bits (1032), Expect = e-112
Identities = 236/616 (38%), Positives = 348/616 (56%), Gaps = 37/616 (6%)
Query: 16 AGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQP 75
AG+C NPGI +G + G ++ D V Y CS L L GS R CQ G WSGTEP C+
Sbjct: 162 AGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 76 YSYDFPEDVAPALGTSFSHMLGATNPT--QKTKESLGRKIQIQRSGHLNLYLLLDCSQSV 133
+ YD P++VA A +S + + + E RKI + SG +N+YL+LD S S+
Sbjct: 222 FMYDTPQEVAEAFLSSLTETIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSI 281
Query: 134 SENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVISSLEN 193
++F K+ +++++ S+ + ++T+A+ PK+ + V +S + V L
Sbjct: 282 GASNFTGAKKCLVNLIEKVASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNE 341
Query: 194 ANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSP 253
NY+DH+ +GTNT AL +VY MM+ + W RH IIL+TDG NMGG P
Sbjct: 342 INYEDHKLKSGTNTKKALQAVYSMMSWPD---DVPPEGWNRTRHVIILMTDGLHNMGGDP 398
Query: 254 KTAVDHIREILNINQ----KRNDYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQD 309
T +D IR++L I + R DYLD+Y GVG L V+ +N L SKKD E+H F ++D
Sbjct: 399 ITVIDEIRDLLYIGKDRKNPREDYLDVYVFGVGPL-VNQVNINALASKKDNEQHVFKVKD 457
Query: 310 TKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIK----PKSQETCRGALI 365
+ L VF M+D S+ + ++CG+ +D + PW I K E+C GA++
Sbjct: 458 MENLEDVFYQMIDESQ-SLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVV 516
Query: 366 SDQWVLTAAHCFR-DGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILE 424
S+ +VLTAAHCF D +HS+ +V+VG K ++ IE + P +++ KK GI E
Sbjct: 517 SEYFVLTAAHCFTVDDKEHSI-KVSVGGEK----RDLEIEVVLFHPNYNINGKKEAGIPE 571
Query: 425 FYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAH 484
FY D+AL+KL K+K RPICLPCT ALR P +TC+ + ELL Q + A
Sbjct: 572 FYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKAL 631
Query: 485 FVALNGSKL---NINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSG---TQE 538
FV+ KL + +K G + SC E +Q + + D+ EVVT +FLC+G
Sbjct: 632 FVSEEEKKLTRKEVYIKNGDKKGSC-ERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYA 690
Query: 539 DESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPP-PRDFH 597
D + C+G+SGG + + +R RF QVG++SWG+ + C KN ++ + +VP RDFH
Sbjct: 691 DPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVC-----KNQKR---QKQVPAHARDFH 742
Query: 598 INLFRMQPWLRQHLGD 613
INLF++ PWL++ L D
Sbjct: 743 INLFQVLPWLKEKLQD 758
Score = 38.9 bits (89), Expect = 0.014
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 18 HCPNP-GISLGAV--RTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQ 74
HCP P G R+ + + D++ + C L GS+ R CQ NG WSG IC
Sbjct: 102 HCPRPHDFENGEYWPRSPY-YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDN 160
Query: 75 PYSY 78
Y
Sbjct: 161 GAGY 164
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 83.2 bits (204), Expect = 7e-16
Identities = 70/252 (27%), Positives = 105/252 (41%), Gaps = 38/252 (15%)
Query: 319 HMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFR 378
H L K T VG A+ + PW V+I+ Q C G+++ WVLTAAHCFR
Sbjct: 187 HCLACGKSLKTPRVVGGEEASV---DSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFR 243
Query: 379 DGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQK 438
D W+V G K + K +I ++ K N DIAL+KL
Sbjct: 244 KHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDN---------DIALMKLQFP 294
Query: 439 VKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLK 498
+ S RPICLP + EL + P + +K N
Sbjct: 295 LTFSGTVRPICLPF------------------FDEEL--TPATPLWIIGWGFTKQNGGKM 334
Query: 499 MGVEWTSCAEVVSQEKTMFPNLTDVRE-VVTDQFLCSGTQE-DESPCKGESGGAVFLERR 556
+ + +V+ + N D + VT++ +C+G E C+G+SGG + +
Sbjct: 335 SDILLQASVQVIDSTRC---NADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD 391
Query: 557 FRFFQVGLVSWG 568
++ VG+VSWG
Sbjct: 392 -QWHVVGIVSWG 402
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 83.2 bits (204), Expect = 7e-16
Identities = 70/252 (27%), Positives = 105/252 (41%), Gaps = 38/252 (15%)
Query: 319 HMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFR 378
H L K T VG A+ + PW V+I+ Q C G+++ WVLTAAHCFR
Sbjct: 192 HCLACGKSLKTPRVVGGEEASV---DSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFR 248
Query: 379 DGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQK 438
D W+V G K + K +I ++ K N DIAL+KL
Sbjct: 249 KHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDN---------DIALMKLQFP 299
Query: 439 VKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLK 498
+ S RPICLP + EL + P + +K N
Sbjct: 300 LTFSGTVRPICLPF------------------FDEEL--TPATPLWIIGWGFTKQNGGKM 339
Query: 499 MGVEWTSCAEVVSQEKTMFPNLTDVRE-VVTDQFLCSGTQE-DESPCKGESGGAVFLERR 556
+ + +V+ + N D + VT++ +C+G E C+G+SGG + +
Sbjct: 340 SDILLQASVQVIDSTRC---NADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD 396
Query: 557 FRFFQVGLVSWG 568
++ VG+VSWG
Sbjct: 397 -QWHVVGIVSWG 407
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 81.6 bits (200), Expect = 2e-15
Identities = 62/248 (25%), Positives = 110/248 (44%), Gaps = 56/248 (22%)
Query: 341 SDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQ---- 396
S + R PW +++ + + C G+L+S +WVL+AAHCF+ S W V +G+ S+
Sbjct: 61 SARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPW 120
Query: 397 ----WGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICL-- 450
+ + ++ +++P G+L +DIALL+LA V + + +PIC+
Sbjct: 121 NLRAYSSRYKVQDIIVNP-------DALGVLR---NDIALLRLASSVTYNAYIQPICIES 170
Query: 451 --------PCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVE 502
P L P G+ N L +++ I +
Sbjct: 171 STFNFVHRPDCWVTGWGLISPSGTPLPPPYN--------------LREAQVTI-----LN 211
Query: 503 WTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDE-SPCKGESGGAVFLERRFRFFQ 561
T C + Q + R ++ D C+G ++ CKG+SGG + ++ ++Q
Sbjct: 212 NTRCNYLFEQPSS--------RSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQ 263
Query: 562 VGLVSWGL 569
VG+VSWG+
Sbjct: 264 VGIVSWGM 271
>gi|148231605 ovochymase 2 [Homo sapiens]
Length = 564
Score = 81.6 bits (200), Expect = 2e-15
Identities = 74/271 (27%), Positives = 118/271 (43%), Gaps = 42/271 (15%)
Query: 347 PWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGD---PKSQWGKEFL- 402
PW V++K + + C G+++S QWV+TAAHC + N S V G+ ++ G++ L
Sbjct: 64 PWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLT 123
Query: 403 IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRR 462
IE +I P F KK DIALLK+A + PICLP L +
Sbjct: 124 IETVIIHPHFS--TKKPMDY------DIALLKMAGAFQFGHFVGPICLP-----ELREQF 170
Query: 463 PQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTD 522
G C L + V L+ +NL + + W C + LT
Sbjct: 171 EAGFICTTAGWGRLTEGGV------LSQVLQEVNLPI-LTWEECVAAL---------LTL 214
Query: 523 VREVVTDQFLCSGTQE-DESPCKGESGGAVFL-ERRFRFFQVGLVSWGLYNPCLGSADKN 580
R + FLC+G + C+G+SGG++ ++ + G+ SWGL +
Sbjct: 215 KRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGL------GCGRG 268
Query: 581 SRKRAPRSKVPPPRDFHINLFRMQPWLRQHL 611
R +S P F ++ ++ PW+ +H+
Sbjct: 269 WRNNVRKSDQGSPGIF-TDISKVLPWIHEHI 298
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 78.2 bits (191), Expect = 2e-14
Identities = 72/252 (28%), Positives = 117/252 (46%), Gaps = 47/252 (18%)
Query: 331 CGVGNMSAN-----ASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHS- 384
CG+ S+ S + PW +++ + + C GALI+D+WV+TAAHCF++ + S
Sbjct: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627
Query: 385 -LWRVNVGD--PKSQWGKE--FLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKV 439
LW V +G S+W E F + + ++ P + + + D+ALL+L V
Sbjct: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEE---------DSHDYDVALLQLDHPV 678
Query: 440 KMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKM 499
S RP+CLP A P G C L + ++ + K+++ L
Sbjct: 679 VRSAAVRPVCLP----ARSHFFEP-GLHCWITGWGALREGGPISNAL----QKVDVQL-- 727
Query: 500 GVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQE-DESPCKGESGGAVFLER-RF 557
+ C+EV R VT + LC+G ++ + C+G+SGG + +
Sbjct: 728 -IPQDLCSEV-------------YRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSG 773
Query: 558 RFFQVGLVSWGL 569
R+F GLVSWGL
Sbjct: 774 RWFLAGLVSWGL 785
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 76.3 bits (186), Expect = 8e-14
Identities = 71/260 (27%), Positives = 113/260 (43%), Gaps = 53/260 (20%)
Query: 329 TICG----VGNMSANASDQE-RTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDH 383
T CG + M QE PW V+I+ C G+LI++QWVLTAAHCFR+ ++
Sbjct: 24 TACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSET 83
Query: 384 SLWRVNVG-------DPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLA 436
SL++V +G P + + + +E + G A D+AL++L
Sbjct: 84 SLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSA------------DVALVELE 131
Query: 437 QKVKMSTHARPICLP---CTMEANL-ALRRPQGSTCRDH---ENELLNKQSVPAHFVALN 489
V + + P+CLP E + GS + E +L K +VP ++
Sbjct: 132 APVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVP----IID 187
Query: 490 GSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQE-DESPCKGESG 548
K N+ ++ E Q KT + + LC+G +E + CKG+SG
Sbjct: 188 TPKCNL------LYSKDTEFGYQPKT-----------IKNDMLCAGFEEGKKDACKGDSG 230
Query: 549 GAVFLERRFRFFQVGLVSWG 568
G + + Q G++SWG
Sbjct: 231 GPLVCLVGQSWLQAGVISWG 250
>gi|33186882 testis serine protease 2 [Homo sapiens]
Length = 293
Score = 75.9 bits (185), Expect = 1e-13
Identities = 59/234 (25%), Positives = 109/234 (46%), Gaps = 35/234 (14%)
Query: 341 SDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKE 400
+++ R PW V+++ K + C G L++ WVLTA HC +S V +GD +S + +
Sbjct: 86 AEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYS---VKMGD-RSVYNEN 141
Query: 401 ----FLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEA 456
+++A + P F + +D+ALL+L V +++ +PIC+P +
Sbjct: 142 TSVVVSVQRAFVHPKFST--------VTTIRNDLALLQLQHPVNFTSNIQPICIP---QE 190
Query: 457 NLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGV-EWTSCAEVVSQEKT 515
N + +G T + V KL + V ++ C E + K
Sbjct: 191 NFQV---EGRT----------RCWVTGWGKTPEREKLASEILQDVDQYIMCYEECN--KI 235
Query: 516 MFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGL 569
+ L+ ++V+ +C ++ + C+G+SGG + E + QVG+VSWG+
Sbjct: 236 IQKALSSTKDVIIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGI 289
>gi|4506115 protein C [Homo sapiens]
Length = 461
Score = 74.7 bits (182), Expect = 2e-13
Identities = 68/231 (29%), Positives = 99/231 (42%), Gaps = 38/231 (16%)
Query: 346 TPWHVTI-KPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPK--SQWGKEFL 402
+PW V + K + C LI WVLTAAHC D + L R+ D + +W +
Sbjct: 223 SPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCM-DESKKLLVRLGEYDLRRWEKWELDLD 281
Query: 403 IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRR 462
I++ + P + N DIALL LAQ +S PICLP + A L +
Sbjct: 282 IKEVFVHPNYSKSTTDN---------DIALLHLAQPATLSQTIVPICLPDSGLAERELNQ 332
Query: 463 PQGSTCRD----HENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFP 518
T H + K++ LN K+ + V C+EV+S
Sbjct: 333 AGQETLVTGWGYHSSR--EKEAKRNRTFVLNFIKIPV-----VPHNECSEVMSN------ 379
Query: 519 NLTDVREVVTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLVSWG 568
+V++ LC+G D + C+G+SGG + +F VGLVSWG
Sbjct: 380 -------MVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG 423
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 74.7 bits (182), Expect = 2e-13
Identities = 69/253 (27%), Positives = 107/253 (42%), Gaps = 53/253 (20%)
Query: 333 VGNMSANASDQERTPWHVTIK---PKSQETCRGALISDQWVLTAAHCF-RDGNDHSLWRV 388
VG + + + + PW V+++ P C G+LI QWVLTAAHC D D + RV
Sbjct: 29 VGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV 88
Query: 389 NVGDPKSQWGKEFL-IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARP 447
+ + + + L + + ++ P F G DIALL+L + V +S+H
Sbjct: 89 QLREQHLYYQDQLLPVSRIIVHPQF---------YTAQIGADIALLELEEPVNVSSHVHT 139
Query: 448 ICLPCTMEANLALRRPQGSTC-------RDHENEL-----LNKQSVPAHFVALNGSKLNI 495
+ LP E P G C D++ L L + VP + +K ++
Sbjct: 140 VTLPPASET-----FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHL 194
Query: 496 NLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLER 555
G DVR +V D LC+G +S C+G+SGG + +
Sbjct: 195 GAYTG--------------------DDVR-IVRDDMLCAGNTRRDS-CQGDSGGPLVCKV 232
Query: 556 RFRFFQVGLVSWG 568
+ Q G+VSWG
Sbjct: 233 NGTWLQAGVVSWG 245
>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
Length = 348
Score = 74.7 bits (182), Expect = 2e-13
Identities = 62/258 (24%), Positives = 109/258 (42%), Gaps = 50/258 (19%)
Query: 326 LTDTICGVGNMSANASDQERTPWHVTIKPKSQET----CRGALISDQWVLTAAHCFRDGN 381
L D + G + + PW V+++ K C G L+ ++WVLTAAHC +D +
Sbjct: 69 LKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS 128
Query: 382 DHSLWRVNVG----DPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQ 437
D +W +G + K+ I+ +I P F ILE Y +DIAL L +
Sbjct: 129 DPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNF---------ILESYVNDIALFHLKK 179
Query: 438 KVKMSTHARPICLPC----TMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKL 493
V+ + + +PICLP ++ N ++ N Q H+++
Sbjct: 180 AVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYIS------ 233
Query: 494 NINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDE-SPCKGESGGAV- 551
E+ + E++ ++ + C+G ++ C+G+SGG +
Sbjct: 234 -------------REMCNSERS-------YGGIIPNTSFCAGDEDGAFDTCRGDSGGPLM 273
Query: 552 -FLERRFRFFQVGLVSWG 568
+L RFF +G+ S+G
Sbjct: 274 CYLPEYKRFFVMGITSYG 291
>gi|4502495 complement component 1, s subcomponent precursor [Homo
sapiens]
Length = 688
Score = 74.3 bits (181), Expect = 3e-13
Identities = 67/239 (28%), Positives = 100/239 (41%), Gaps = 37/239 (15%)
Query: 341 SDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKE 400
+D + PW V GALI++ WVLTAAH + +++ + S+ K
Sbjct: 444 ADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKS 500
Query: 401 FLI--EKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCT----- 453
++ E I PG+ + + +G F +DIAL++L VKM PICLP T
Sbjct: 501 KMLTPEHVFIHPGWKLL-EVPEGRTNF-DNDIALVRLKDPVKMGPTVSPICLPGTSSDYN 558
Query: 454 -MEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQ 512
M+ +L L G T + L +P C EV
Sbjct: 559 LMDGDLGLISGWGRTEKRDRAVRLKAARLPV-----------------APLRKCKEV--- 598
Query: 513 EKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLE---RRFRFFQVGLVSWG 568
K P V T +C+G ++ CKG+SGGA ++ + +F+ GLVSWG
Sbjct: 599 -KVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWG 656
>gi|41393602 complement component 1, s subcomponent precursor [Homo
sapiens]
Length = 688
Score = 74.3 bits (181), Expect = 3e-13
Identities = 67/239 (28%), Positives = 100/239 (41%), Gaps = 37/239 (15%)
Query: 341 SDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKE 400
+D + PW V GALI++ WVLTAAH + +++ + S+ K
Sbjct: 444 ADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKS 500
Query: 401 FLI--EKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCT----- 453
++ E I PG+ + + +G F +DIAL++L VKM PICLP T
Sbjct: 501 KMLTPEHVFIHPGWKLL-EVPEGRTNF-DNDIALVRLKDPVKMGPTVSPICLPGTSSDYN 558
Query: 454 -MEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQ 512
M+ +L L G T + L +P C EV
Sbjct: 559 LMDGDLGLISGWGRTEKRDRAVRLKAARLPV-----------------APLRKCKEV--- 598
Query: 513 EKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLE---RRFRFFQVGLVSWG 568
K P V T +C+G ++ CKG+SGGA ++ + +F+ GLVSWG
Sbjct: 599 -KVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWG 656
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 74.3 bits (181), Expect = 3e-13
Identities = 68/253 (26%), Positives = 108/253 (42%), Gaps = 53/253 (20%)
Query: 333 VGNMSANASDQERTPWHVTIKPKSQ---ETCRGALISDQWVLTAAHCF-RDGNDHSLWRV 388
VG + + + + PW V+++ + + C G+LI QWVLTAAHC D D + RV
Sbjct: 29 VGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV 88
Query: 389 NVGDPKSQWGKEFL-IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARP 447
+ + + + L + + ++ P F G DIALL+L + V +S+H
Sbjct: 89 QLREQHLYYQDQLLPVSRIIVHPQF---------YTAQIGADIALLELEEPVNVSSHVHT 139
Query: 448 ICLPCTMEANLALRRPQGSTC-------RDHENEL-----LNKQSVPAHFVALNGSKLNI 495
+ LP E P G C D++ L L + VP + +K ++
Sbjct: 140 VTLPPASET-----FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHL 194
Query: 496 NLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLER 555
G DVR +V D LC+G +S C+G+SGG + +
Sbjct: 195 GAYTG--------------------DDVR-IVRDDMLCAGNTRRDS-CQGDSGGPLVCKV 232
Query: 556 RFRFFQVGLVSWG 568
+ Q G+VSWG
Sbjct: 233 NGTWLQAGVVSWG 245
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 73.9 bits (180), Expect = 4e-13
Identities = 64/230 (27%), Positives = 105/230 (45%), Gaps = 35/230 (15%)
Query: 347 PWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG----DPKSQWGKEFL 402
PW V+I + C G+L+S+QWVL+AAHCF + + V +G D S+ K
Sbjct: 57 PWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVST 116
Query: 403 IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRR 462
++ + P + + +QG DIALL+L++ + S + RPICLP AN +
Sbjct: 117 LKDIIPHPSY--LQEGSQG-------DIALLQLSRPITFSRYIRPICLPA---ANASF-- 162
Query: 463 PQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGV---EWTSCAEVVSQEKTMFPN 519
P G C + A V+L K L++ + E +C + +
Sbjct: 163 PNGLHC------TVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK------ 210
Query: 520 LTDVREVVTDQFLCSGTQE-DESPCKGESGGAVFLERRFRFFQVGLVSWG 568
+ V + +C+G E + C+G+SGG + ++ G+VSWG
Sbjct: 211 -PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG 259
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 73.6 bits (179), Expect = 5e-13
Identities = 66/230 (28%), Positives = 101/230 (43%), Gaps = 33/230 (14%)
Query: 344 ERTPWHVTIKPKSQETCRGALISDQWVLTAAHC-FRD-GNDHSLWRV-NVGDPKSQWGKE 400
++ PW V+++ + C G+LI +WVLTAAHC FR G + W + +G W
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKH- 230
Query: 401 FLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLAL 460
+E + FD FA DIAL LA V S+H +P CLP
Sbjct: 231 --LEDIIFPSNFD-FATLT--------SDIALALLAYSVNYSSHIQPACLP-----EKLF 274
Query: 461 RRPQGSTC-RDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPN 519
G+ C ++ S P V L ++LNI + C E++ +
Sbjct: 275 EVEAGTECWVTGWGQVSESVSGPMPLV-LQETELNI-----MRHEKCCEMLKNKN----- 323
Query: 520 LTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGL 569
++VT +C + + C+G+SGG + E + QVG+VSWG+
Sbjct: 324 -ISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGI 372
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 73.6 bits (179), Expect = 5e-13
Identities = 66/230 (28%), Positives = 101/230 (43%), Gaps = 33/230 (14%)
Query: 344 ERTPWHVTIKPKSQETCRGALISDQWVLTAAHC-FRD-GNDHSLWRV-NVGDPKSQWGKE 400
++ PW V+++ + C G+LI +WVLTAAHC FR G + W + +G W
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKH- 230
Query: 401 FLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLAL 460
+E + FD FA DIAL LA V S+H +P CLP
Sbjct: 231 --LEDIIFPSNFD-FATLT--------SDIALALLAYSVNYSSHIQPACLP-----EKLF 274
Query: 461 RRPQGSTC-RDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPN 519
G+ C ++ S P V L ++LNI + C E++ +
Sbjct: 275 EVEAGTECWVTGWGQVSESVSGPMPLV-LQETELNI-----MRHEKCCEMLKNKN----- 323
Query: 520 LTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGL 569
++VT +C + + C+G+SGG + E + QVG+VSWG+
Sbjct: 324 -ISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGI 372
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 73.6 bits (179), Expect = 5e-13
Identities = 66/230 (28%), Positives = 101/230 (43%), Gaps = 33/230 (14%)
Query: 344 ERTPWHVTIKPKSQETCRGALISDQWVLTAAHC-FRD-GNDHSLWRV-NVGDPKSQWGKE 400
++ PW V+++ + C G+LI +WVLTAAHC FR G + W + +G W
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRWDQAWKH- 230
Query: 401 FLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLAL 460
+E + FD FA DIAL LA V S+H +P CLP
Sbjct: 231 --LEDIIFPSNFD-FATLT--------SDIALALLAYSVNYSSHIQPACLP-----EKLF 274
Query: 461 RRPQGSTC-RDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPN 519
G+ C ++ S P V L ++LNI + C E++ +
Sbjct: 275 EVEAGTECWVTGWGQVSESVSGPMPLV-LQETELNI-----MRHEKCCEMLKNKN----- 323
Query: 520 LTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGL 569
++VT +C + + C+G+SGG + E + QVG+VSWG+
Sbjct: 324 -ISKSKMVTRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGI 372
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 73.6 bits (179), Expect = 5e-13
Identities = 69/253 (27%), Positives = 116/253 (45%), Gaps = 55/253 (21%)
Query: 333 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFR---DGNDHSLW--R 387
VG A A R PW V++ C G+L+S++ +LTAAHC + +++W
Sbjct: 29 VGGQDAAAG---RWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFSYTVWLGS 85
Query: 388 VNVGDPKSQWGKEFLIEKAVISPGF-DVFAKKNQGILEFYGDDIALLKLAQKVKMSTHAR 446
+ VGD + + ++ + K VI P + D A D+ALLKL+ +V ++
Sbjct: 86 ITVGDSRKR--VKYYVSKIVIHPKYQDTTA------------DVALLKLSSQVTFTSAIL 131
Query: 447 PICLPCTMEANLAL---------RRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINL 497
PICLP ++ LA+ + + S+ RD+ + L + VP
Sbjct: 132 PICLP-SVTKQLAIPPFCWVTGWGKVKESSDRDY-HSALQEAEVPI-------------- 175
Query: 498 KMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSG-TQEDESPCKGESGGAVFLERR 556
++ +C ++ + P L V+ + +C+G TQ + CKG+SGG +
Sbjct: 176 ---IDRQACEQLYNPIGIFLPAL---EPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHID 229
Query: 557 FRFFQVGLVSWGL 569
+ Q G+VSWGL
Sbjct: 230 GVWIQTGVVSWGL 242
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 73.2 bits (178), Expect = 7e-13
Identities = 78/282 (27%), Positives = 126/282 (44%), Gaps = 81/282 (28%)
Query: 320 MLDVSK-----LTDTICG--------VGNMSAN--ASDQERTPWHVTIKPKSQETCRGAL 364
++++SK LT+ CG GN N +S + PW +++ K + C +L
Sbjct: 155 LMEISKAASEMLTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASL 214
Query: 365 ISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGIL- 423
IS +W+L+AAHCF N+ W VN G ++ K ++ +K Q I+
Sbjct: 215 ISSRWLLSAAHCFAKKNNSKDWTVNFG---------IVVNKPYMT-------RKVQNIIF 258
Query: 424 -EFYG-----DDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLN 477
E Y DDIAL++LA++V + + R ICLP EA + L +++N ++
Sbjct: 259 HENYSSPGLHDDIALVQLAEEVSFTEYIRKICLP---EAKMKL--------SENDNVVVT 307
Query: 478 KQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVR---------EVVT 528
+ +NGS V+ QE F + D + VT
Sbjct: 308 GWGT----LYMNGS---------------FPVILQED--FLKIIDNKICNASYAYSGFVT 346
Query: 529 DQFLCSGTQEDES-PCKGESGGAV-FLERRFRFFQVGLVSWG 568
D LC+G E+ C+ +SGG + + + R + VG+VSWG
Sbjct: 347 DTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWG 388
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 72.0 bits (175), Expect = 2e-12
Identities = 65/246 (26%), Positives = 97/246 (39%), Gaps = 51/246 (20%)
Query: 336 MSANASDQERTPWHVTI---KPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGD 392
+ AS + PW VT+ P + C G++I +QW+LTAAHCF + RV G
Sbjct: 389 VGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGI 448
Query: 393 PKSQWGKE----FLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPI 448
KE F +++ +I + + G DIALLKL V + RPI
Sbjct: 449 LNQSEIKEDTSFFGVQEIIIHDQYKMAES---------GYDIALLKLETTVNYTDSQRPI 499
Query: 449 CLPCTMEANLALRRPQGS-----TCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEW 503
CLP + N+ + RD L K +P V
Sbjct: 500 CLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPL-----------------VTN 542
Query: 504 TSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQE-DESPCKGESGGAVFLERRFRFFQV 562
C + K +T + +C+G +E + CKG+SGG + + + V
Sbjct: 543 EECQKRYRGHK------------ITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLV 590
Query: 563 GLVSWG 568
G+ SWG
Sbjct: 591 GITSWG 596
>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
precursor [Homo sapiens]
Length = 686
Score = 71.2 bits (173), Expect = 3e-12
Identities = 76/237 (32%), Positives = 108/237 (45%), Gaps = 46/237 (19%)
Query: 347 PWHVTIKPKSQETCRGALISDQWVLTAAHC-FRDGNDHSLWRVNVGDPK-------SQWG 398
PW V I + T GAL+ D WVLTAAH + +D S + +G K W
Sbjct: 457 PWQVLILGGT--TAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWS 514
Query: 399 KE-FLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEAN 457
+ F+ E GFD +DIAL+KL KV ++++ PICLP EA
Sbjct: 515 EAVFIHEGYTHDAGFD--------------NDIALIKLNNKVVINSNITPICLP-RKEAE 559
Query: 458 LALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMF 517
+R T L ++ F+A N ++I + V+ C + EK +
Sbjct: 560 SFMRTDDIGTASGWG---LTQRG----FLARNLMYVDIPI---VDHQKC--TAAYEKPPY 607
Query: 518 PNLTDVREVVTDQFLCSGTQE-DESPCKGESGGA-VFLERRF-RFFQVGLVSWGLYN 571
P R VT LC+G + + C+G+SGGA VFL+ R+F G+VSWG N
Sbjct: 608 P-----RGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 659
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 70.9 bits (172), Expect = 3e-12
Identities = 58/227 (25%), Positives = 99/227 (43%), Gaps = 28/227 (12%)
Query: 347 PWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG----DPKSQWGKEFL 402
PW +I+ + C G+LI+ QWVLTAAHCF + +RV +G S
Sbjct: 49 PWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVP 108
Query: 403 IEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRR 462
+ + ++ P + + D+ALL+L + V +S +P+CLP R
Sbjct: 109 VRRVLLPPDYSEDGARG---------DLALLQLRRPVPLSARVQPVCLPVP-----GARP 154
Query: 463 PQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTD 522
P G+ CR L + L G ++ + ++ +C + + ++
Sbjct: 155 PPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPL-----LDSRTCDGLYH----VGADVPQ 205
Query: 523 VREVVTDQFLCSG-TQEDESPCKGESGGAVFLERRFRFFQVGLVSWG 568
+V LC+G Q + C+G+SGG + + + VG+VSWG
Sbjct: 206 AERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWG 252
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 70.5 bits (171), Expect = 4e-12
Identities = 57/239 (23%), Positives = 100/239 (41%), Gaps = 34/239 (14%)
Query: 333 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGD 392
VG M A+ + PW +++ + C A+I+ +W+++AAHCF + D + W VG
Sbjct: 204 VGGMEASPGE---FPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGA 260
Query: 393 PKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPC 452
+ + V+ N +F D+A+L+L + H +P+CLP
Sbjct: 261 TYLSGSEASTVRAQVVQ--IVKHPLYNADTADF---DVAVLELTSPLPFGRHIQPVCLPA 315
Query: 453 TMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQ 512
++ S + + L K V K + L ++ CA +
Sbjct: 316 ATHIFPPSKKCLISGWGYLKEDFLVKPEVL--------QKATVEL---LDQALCASLYGH 364
Query: 513 EKTMFPNLTDVREVVTDQFLCSGTQEDE-SPCKGESGGAVFLER-RFRFFQVGLVSWGL 569
+TD+ +C+G + + C+G+SGG + E RFF G+VSWG+
Sbjct: 365 S-------------LTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGI 410
Score = 68.6 bits (166), Expect = 2e-11
Identities = 64/254 (25%), Positives = 110/254 (43%), Gaps = 65/254 (25%)
Query: 333 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGD 392
VG A + + PW V++K S+ C ++ D+W+L+AAHCF + R ++G
Sbjct: 505 VGGFGAASGE---VPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQV-RAHLGT 560
Query: 393 PK--SQWGKEFLI--EKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPI 448
G I + V+ P + N GIL+F D+A+L+LA + + + +P+
Sbjct: 561 ASLLGLGGSPVKIGLRRVVLHPLY------NPGILDF---DLAVLELASPLAFNKYIQPV 611
Query: 449 CLPCTMEANLALRRPQGSTC-----------RDHENELLNKQSVPAHFVALNGSKLNINL 497
CLP ++ + P G C + ELL K SV
Sbjct: 612 CLPLAIQ-----KFPVGRKCMISGWGNTQEGNATKPELLQKASVGI-------------- 652
Query: 498 KMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDE-SPCKGESGGAVFLERR 556
++ +C+ + + +TD+ +C+G E + C+G+SGG + E
Sbjct: 653 ---IDQKTCSVLYNFS-------------LTDRMICAGFLEGKVDSCQGDSGGPLACEEA 696
Query: 557 -FRFFQVGLVSWGL 569
F+ G+VSWG+
Sbjct: 697 PGVFYLAGIVSWGI 710
Score = 61.6 bits (148), Expect = 2e-09
Identities = 60/241 (24%), Positives = 102/241 (42%), Gaps = 45/241 (18%)
Query: 336 MSANASDQERTPWHVTIKPKSQE-TCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDP- 393
+ +A+ + PW V++ + +E C L++++W+L+AAHCF D W +G P
Sbjct: 828 VGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPF 887
Query: 394 -KSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPC 452
G+ + + P ++++ L++ D+ALL+LA V+ S RPICLP
Sbjct: 888 LSGAEGQLERVARIYKHPFYNLYT------LDY---DVALLELAGPVRRSRLVRPICLP- 937
Query: 453 TMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQ 512
A R P G+ C V + M + A +
Sbjct: 938 ----EPAPRPPDGTRC-----------------VITGWGSVREGGSMARQLQKAAVRLLS 976
Query: 513 EKT---MFPNLTDVREVVTDQFLCSG-TQEDESPCKGESGGAVFL-ERRFRFFQVGLVSW 567
E+T +P ++ + LC+G Q C G++GG + E R+ G+ SW
Sbjct: 977 EQTCRRFYP------VQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSW 1030
Query: 568 G 568
G
Sbjct: 1031 G 1031
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 70.1 bits (170), Expect = 6e-12
Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 43/234 (18%)
Query: 343 QERTPWHVTIKPKSQETCRGALISDQWVLTAAHCF-RDGNDH------SLWRVNVGDPKS 395
+ + PW V++ C G+++++ WVL+AAHCF RD N L + V +
Sbjct: 68 ERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHT 127
Query: 396 QWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTME 455
QW + + + ++ P ++++ G D+AL++L ++ S P+CL T E
Sbjct: 128 QW---YEVNRVILHPTYEMYHP--------IGGDVALVQLKTRIVFSESVLPVCL-ATPE 175
Query: 456 ANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKT 515
NL + C L++KQ + L +L + L+ W C +
Sbjct: 176 VNLT-----SANCWATGWGLVSKQGETSD--ELQEMQLPLILE---PW--CHLLYGHMSY 223
Query: 516 MFPNLTDVREVVTDQFLCSG-TQEDESPCKGESGGAVFLERRFRFFQVGLVSWG 568
+ P++ LC+G ++ C+G+SGG + E + Q+G+VSWG
Sbjct: 224 IMPDM-----------LCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWG 266
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 69.7 bits (169), Expect = 8e-12
Identities = 63/232 (27%), Positives = 98/232 (42%), Gaps = 34/232 (14%)
Query: 345 RTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGND-HSLWRVNVG--DPKSQWGKEF 401
R PW V+++ C G+L+S WVLTAAHCF + N S WRV G S G +
Sbjct: 173 RWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQL 232
Query: 402 LIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALR 461
++ V G+ F N E +DIAL+ L+ + ++ + +P+CLP +A +
Sbjct: 233 GVQAVVYHGGYLPFRDPNS---EENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALV--- 286
Query: 462 RPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLT 521
G C V G+ + GV + ++S + +
Sbjct: 287 --DGKICT----------------VTGWGNTQYYGQQAGVLQEARVPIISND--VCNGAD 326
Query: 522 DVREVVTDQFLCSGTQEDE-SPCKGESGGAVFLE----RRFRFFQVGLVSWG 568
+ + C+G E C+G+SGG E R R+ G+VSWG
Sbjct: 327 FYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 378
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 69.7 bits (169), Expect = 8e-12
Identities = 63/232 (27%), Positives = 98/232 (42%), Gaps = 34/232 (14%)
Query: 345 RTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGND-HSLWRVNVG--DPKSQWGKEF 401
R PW V+++ C G+L+S WVLTAAHCF + N S WRV G S G +
Sbjct: 173 RWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQL 232
Query: 402 LIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALR 461
++ V G+ F N E +DIAL+ L+ + ++ + +P+CLP +A +
Sbjct: 233 GVQAVVYHGGYLPFRDPNS---EENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALV--- 286
Query: 462 RPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLT 521
G C V G+ + GV + ++S + +
Sbjct: 287 --DGKICT----------------VTGWGNTQYYGQQAGVLQEARVPIISND--VCNGAD 326
Query: 522 DVREVVTDQFLCSGTQEDE-SPCKGESGGAVFLE----RRFRFFQVGLVSWG 568
+ + C+G E C+G+SGG E R R+ G+VSWG
Sbjct: 327 FYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 378
>gi|7019563 testes-specific protease 50 [Homo sapiens]
Length = 385
Score = 69.7 bits (169), Expect = 8e-12
Identities = 65/247 (26%), Positives = 97/247 (39%), Gaps = 61/247 (24%)
Query: 345 RTPWHVTIKPKSQETCRGALISDQWVLTAAHC--FRDGNDHSLWRVNVGDPKSQWGKEFL 402
R PW V+++ C G +I+ QWVLT AHC +RD ++ V VG P W + +
Sbjct: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD----VIYSVRVGSP---WIDQ-M 174
Query: 403 IEKAVISPGFDVFAKKNQGILEFY-----GDDIALLKLAQKVKMSTHARPICLP------ 451
+ A P V F+ +DI LLKL Q++K S + RPICLP
Sbjct: 175 TQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVL 234
Query: 452 -----CTMEANLALRR-----PQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGV 501
CT+ L + PQ T ++ E +LN + +
Sbjct: 235 KDHSRCTV-TGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFY---------------- 277
Query: 502 EWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQ 561
T P L +++ Q +C+ E C +G + ++
Sbjct: 278 ----------HNFTKIPTLV---QIIKSQMMCAEDTHREKFCYELTGEPLVCSMEGTWYL 324
Query: 562 VGLVSWG 568
VGLVSWG
Sbjct: 325 VGLVSWG 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,169,257
Number of Sequences: 37866
Number of extensions: 1082742
Number of successful extensions: 3029
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 2248
Number of HSP's gapped (non-prelim): 690
length of query: 620
length of database: 18,247,518
effective HSP length: 108
effective length of query: 512
effective length of database: 14,157,990
effective search space: 7248890880
effective search space used: 7248890880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.