Search of human proteins with 224994164

Search of human proteins with 224994164

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224994164 mitochondrial fission regulator 1 isoform 3 [Homo
sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224994164 mitochondrial fission regulator 1 isoform 3 [Homo s...   691   0.0  
gi|224994160 mitochondrial fission regulator 1 isoform 1 [Homo s...   617   e-177
gi|224994162 mitochondrial fission regulator 1 isoform 2 [Homo s...   534   e-152
gi|149999350 DUF729 domain containing 1 [Homo sapiens]                127   2e-29
gi|39653315 DUF729 domain containing 1 [Homo sapiens]                 127   2e-29
gi|153251766 hypothetical protein LOC56181 isoform a [Homo sapiens]    91   1e-18
gi|153251748 hypothetical protein LOC56181 isoform a [Homo sapiens]    91   1e-18
gi|153251745 hypothetical protein LOC56181 isoform a [Homo sapiens]    91   1e-18
gi|153251771 hypothetical protein LOC56181 isoform b [Homo sapiens]    78   1e-14
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    47   2e-05
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    45   1e-04
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    45   1e-04
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]                      44   3e-04
gi|187761324 shootin1 isoform a [Homo sapiens]                         43   4e-04
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    43   5e-04
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    43   5e-04
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    43   5e-04
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    43   5e-04
gi|120587019 zinc finger protein 318 [Homo sapiens]                    42   8e-04
gi|195947369 junction-mediating and regulatory protein [Homo sap...    41   0.001
gi|119120861 formin-like 3 isoform 2 [Homo sapiens]                    41   0.001
gi|119120874 formin-like 3 isoform 1 [Homo sapiens]                    41   0.001
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]     41   0.002
gi|13699803 WAS protein family, member 3 [Homo sapiens]                40   0.002
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]    40   0.002
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             40   0.004
gi|19923391 homeobox D3 [Homo sapiens]                                 40   0.004
gi|50511340 shootin1 isoform b [Homo sapiens]                          40   0.004
gi|146134388 YLP motif containing 1 [Homo sapiens]                     40   0.004
gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]             39   0.005

>gi|224994164 mitochondrial fission regulator 1 isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  691 bits (1784), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHA 60
           MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHA
Sbjct: 1   MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHA 60

Query: 61  TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL 120
           TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL
Sbjct: 61  TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL 120

Query: 121 PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF 180
           PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF
Sbjct: 121 PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF 180

Query: 181 GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE 240
           GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE
Sbjct: 181 GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE 240

Query: 241 ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK 300
           ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK
Sbjct: 241 ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK 300

Query: 301 SESEATSERVLVSYLPRFLSCYVEIHPIAKHLHFASDSPVSSVSSKGR 348
           SESEATSERVLVSYLPRFLSCYVEIHPIAKHLHFASDSPVSSVSSKGR
Sbjct: 301 SESEATSERVLVSYLPRFLSCYVEIHPIAKHLHFASDSPVSSVSSKGR 348


>gi|224994160 mitochondrial fission regulator 1 isoform 1 [Homo
           sapiens]
          Length = 333

 Score =  617 bits (1591), Expect = e-177
 Identities = 311/311 (100%), Positives = 311/311 (100%)

Query: 1   MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHA 60
           MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHA
Sbjct: 1   MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHA 60

Query: 61  TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL 120
           TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL
Sbjct: 61  TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL 120

Query: 121 PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF 180
           PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF
Sbjct: 121 PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF 180

Query: 181 GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE 240
           GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE
Sbjct: 181 GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE 240

Query: 241 ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK 300
           ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK
Sbjct: 241 ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK 300

Query: 301 SESEATSERVL 311
           SESEATSERVL
Sbjct: 301 SESEATSERVL 311


>gi|224994162 mitochondrial fission regulator 1 isoform 2 [Homo
           sapiens]
          Length = 300

 Score =  534 bits (1376), Expect = e-152
 Identities = 278/311 (89%), Positives = 278/311 (89%), Gaps = 33/311 (10%)

Query: 1   MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHA 60
           MLGWIKRLIRMVFQQVGVSMQS                                 INSHA
Sbjct: 1   MLGWIKRLIRMVFQQVGVSMQS---------------------------------INSHA 27

Query: 61  TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL 120
           TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL
Sbjct: 28  TEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISL 87

Query: 121 PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF 180
           PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF
Sbjct: 88  PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF 147

Query: 181 GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE 240
           GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE
Sbjct: 148 GTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLE 207

Query: 241 ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK 300
           ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK
Sbjct: 208 ILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPK 267

Query: 301 SESEATSERVL 311
           SESEATSERVL
Sbjct: 268 SESEATSERVL 278


>gi|149999350 DUF729 domain containing 1 [Homo sapiens]
          Length = 385

 Score =  127 bits (318), Expect = 2e-29
 Identities = 105/324 (32%), Positives = 155/324 (47%), Gaps = 46/324 (14%)

Query: 5   IKRLIRMVFQQVGVSMQSVL--WSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATE 62
           I  ++R + +  GV ++ VL  W  K YGS+RSIVR IG  L L  C R  F++      
Sbjct: 4   ILNILREMLEYFGVPVEQVLLIWENKDYGSTRSIVRIIGKMLPLEPCRRPNFELIPLLNS 63

Query: 63  WSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISLPD 122
               + G   V SFAD+ +VA +E     R R  +      + ++ F      R    P 
Sbjct: 64  VDSDNCGS-MVPSFADILYVANDEEASYLRFRNSIWKNEEEKVEI-FHPLRLVRDPLSPA 121

Query: 123 LSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQN------------- 169
           + Q+E  +K     NE A++KI ALENEL  LR+QIA IV  QE +N             
Sbjct: 122 VRQKET-VKNDLPVNEAAIRKIAALENELTFLRSQIAAIVEMQELKNSTNSSSFGLSDER 180

Query: 170 LTAGDLDSTTFGTIPPHP---------PPPPPPLP-------PPAL-----GLHQSTSAV 208
           ++ G L S+    +   P         PPPPPPLP       PP       G +    + 
Sbjct: 181 ISLGQLSSSRAAHLSVDPDQLPGSVLSPPPPPPLPPQFSSLQPPCFPPVQPGSNNICDSD 240

Query: 209 DLIKERREKRANAGKTLVKNNPK---KPEMPNMLEILKEMNSVKLRSVKRSEQ----DVK 261
           +   E  ++   A KT   ++ K     ++PNML++LK+MN VKLR+++RS        +
Sbjct: 241 NPATEMSKQNPAANKTNYSHHSKSQRNKDIPNMLDVLKDMNKVKLRAIERSPGGRPIHKR 300

Query: 262 PKPVDATDPAALIAEALKKKFAYR 285
            +     DP +LI+ ALK+KFA++
Sbjct: 301 KRQNSHWDPVSLISHALKQKFAFQ 324


>gi|39653315 DUF729 domain containing 1 [Homo sapiens]
          Length = 385

 Score =  127 bits (318), Expect = 2e-29
 Identities = 105/324 (32%), Positives = 155/324 (47%), Gaps = 46/324 (14%)

Query: 5   IKRLIRMVFQQVGVSMQSVL--WSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATE 62
           I  ++R + +  GV ++ VL  W  K YGS+RSIVR IG  L L  C R  F++      
Sbjct: 4   ILNILREMLEYFGVPVEQVLLIWENKDYGSTRSIVRIIGKMLPLEPCRRPNFELIPLLNS 63

Query: 63  WSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPPLQDDLLFFEKAPSRQISLPD 122
               + G   V SFAD+ +VA +E     R R  +      + ++ F      R    P 
Sbjct: 64  VDSDNCGS-MVPSFADILYVANDEEASYLRFRNSIWKNEEEKVEI-FHPLRLVRDPLSPA 121

Query: 123 LSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQN------------- 169
           + Q+E  +K     NE A++KI ALENEL  LR+QIA IV  QE +N             
Sbjct: 122 VRQKET-VKNDLPVNEAAIRKIAALENELTFLRSQIAAIVEMQELKNSTNSSSFGLSDER 180

Query: 170 LTAGDLDSTTFGTIPPHP---------PPPPPPLP-------PPAL-----GLHQSTSAV 208
           ++ G L S+    +   P         PPPPPPLP       PP       G +    + 
Sbjct: 181 ISLGQLSSSRAAHLSVDPDQLPGSVLSPPPPPPLPPQFSSLQPPCFPPVQPGSNNICDSD 240

Query: 209 DLIKERREKRANAGKTLVKNNPK---KPEMPNMLEILKEMNSVKLRSVKRSEQ----DVK 261
           +   E  ++   A KT   ++ K     ++PNML++LK+MN VKLR+++RS        +
Sbjct: 241 NPATEMSKQNPAANKTNYSHHSKSQRNKDIPNMLDVLKDMNKVKLRAIERSPGGRPIHKR 300

Query: 262 PKPVDATDPAALIAEALKKKFAYR 285
            +     DP +LI+ ALK+KFA++
Sbjct: 301 KRQNSHWDPVSLISHALKQKFAFQ 324


>gi|153251766 hypothetical protein LOC56181 isoform a [Homo sapiens]
          Length = 292

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 88/296 (29%), Positives = 136/296 (45%), Gaps = 58/296 (19%)

Query: 24  LWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVA 83
           +W  KP+G++RS+VR+IGTNL L  C R  F+   + ++          V + AD+ W+A
Sbjct: 12  IWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLR--DVPPVPTLADIAWIA 69

Query: 84  KEEGECSARLRTEVRSRPPLQDDLLFFEKAP----SRQISLPDLSQEEPQ---LKTPALA 136
            +E E  AR+R++ R   PL+     ++ +P     R  S+P+L   E +   LK PAL 
Sbjct: 70  ADEEETYARVRSDTR---PLRHT---WKPSPLIVMQRNASVPNLRGSEERLLALKKPAL- 122

Query: 137 NEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPLPP 196
              AL +   L++EL+ LR+QIAKIV              S T   + P       PLP 
Sbjct: 123 --PALSRTTELQDELSHLRSQIAKIVAADAAS-------ASLTPDFLSPGSSNVSSPLPC 173

Query: 197 PALGLHQSTSAV--DLIKERREK--RANAGKTLVKNNPK--KPE---------------- 234
                H +TS V  D+ +E   +     +   L   +P+  KPE                
Sbjct: 174 FGSSFHSTTSFVISDITEETEVEVPELPSVPLLCSASPECCKPEHKAACSSSEEDDCVSL 233

Query: 235 -----MPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYR 285
                  +M+ ILK+ + +K        QD+    +   DPA LI+E L++KFA +
Sbjct: 234 SKASSFADMMGILKDFHRMK------QSQDLNRSLLKEEDPAVLISEVLRRKFALK 283


>gi|153251748 hypothetical protein LOC56181 isoform a [Homo sapiens]
          Length = 292

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 88/296 (29%), Positives = 136/296 (45%), Gaps = 58/296 (19%)

Query: 24  LWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVA 83
           +W  KP+G++RS+VR+IGTNL L  C R  F+   + ++          V + AD+ W+A
Sbjct: 12  IWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLR--DVPPVPTLADIAWIA 69

Query: 84  KEEGECSARLRTEVRSRPPLQDDLLFFEKAP----SRQISLPDLSQEEPQ---LKTPALA 136
            +E E  AR+R++ R   PL+     ++ +P     R  S+P+L   E +   LK PAL 
Sbjct: 70  ADEEETYARVRSDTR---PLRHT---WKPSPLIVMQRNASVPNLRGSEERLLALKKPAL- 122

Query: 137 NEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPLPP 196
              AL +   L++EL+ LR+QIAKIV              S T   + P       PLP 
Sbjct: 123 --PALSRTTELQDELSHLRSQIAKIVAADAAS-------ASLTPDFLSPGSSNVSSPLPC 173

Query: 197 PALGLHQSTSAV--DLIKERREK--RANAGKTLVKNNPK--KPE---------------- 234
                H +TS V  D+ +E   +     +   L   +P+  KPE                
Sbjct: 174 FGSSFHSTTSFVISDITEETEVEVPELPSVPLLCSASPECCKPEHKAACSSSEEDDCVSL 233

Query: 235 -----MPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYR 285
                  +M+ ILK+ + +K        QD+    +   DPA LI+E L++KFA +
Sbjct: 234 SKASSFADMMGILKDFHRMK------QSQDLNRSLLKEEDPAVLISEVLRRKFALK 283


>gi|153251745 hypothetical protein LOC56181 isoform a [Homo sapiens]
          Length = 292

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 88/296 (29%), Positives = 136/296 (45%), Gaps = 58/296 (19%)

Query: 24  LWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVA 83
           +W  KP+G++RS+VR+IGTNL L  C R  F+   + ++          V + AD+ W+A
Sbjct: 12  IWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLR--DVPPVPTLADIAWIA 69

Query: 84  KEEGECSARLRTEVRSRPPLQDDLLFFEKAP----SRQISLPDLSQEEPQ---LKTPALA 136
            +E E  AR+R++ R   PL+     ++ +P     R  S+P+L   E +   LK PAL 
Sbjct: 70  ADEEETYARVRSDTR---PLRHT---WKPSPLIVMQRNASVPNLRGSEERLLALKKPAL- 122

Query: 137 NEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPLPP 196
              AL +   L++EL+ LR+QIAKIV              S T   + P       PLP 
Sbjct: 123 --PALSRTTELQDELSHLRSQIAKIVAADAAS-------ASLTPDFLSPGSSNVSSPLPC 173

Query: 197 PALGLHQSTSAV--DLIKERREK--RANAGKTLVKNNPK--KPE---------------- 234
                H +TS V  D+ +E   +     +   L   +P+  KPE                
Sbjct: 174 FGSSFHSTTSFVISDITEETEVEVPELPSVPLLCSASPECCKPEHKAACSSSEEDDCVSL 233

Query: 235 -----MPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYR 285
                  +M+ ILK+ + +K        QD+    +   DPA LI+E L++KFA +
Sbjct: 234 SKASSFADMMGILKDFHRMK------QSQDLNRSLLKEEDPAVLISEVLRRKFALK 283


>gi|153251771 hypothetical protein LOC56181 isoform b [Homo sapiens]
          Length = 205

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 54/146 (36%), Positives = 83/146 (56%), Gaps = 18/146 (12%)

Query: 24  LWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVA 83
           +W  KP+G++RS+VR+IGTNL L  C R  F+   + ++          V + AD+ W+A
Sbjct: 12  IWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLR--DVPPVPTLADIAWIA 69

Query: 84  KEEGECSARLRTEVRSRPPLQDDLLFFEKAP----SRQISLPDLSQEEPQ---LKTPALA 136
            +E E  AR+R++ R   PL+     ++ +P     R  S+P+L   E +   LK PAL 
Sbjct: 70  ADEEETYARVRSDTR---PLRHT---WKPSPLIVMQRNASVPNLRGSEERLLALKKPAL- 122

Query: 137 NEEALQKICALENELAALRAQIAKIV 162
              AL +   L++EL+ LR+QIAKIV
Sbjct: 123 --PALSRTTELQDELSHLRSQIAKIV 146


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 7/117 (5%)

Query: 184 PPHPPPPPPPLPPPALGL-----HQ-STSAVDLIKERREKRANAGKTLVKNNPKKPEMPN 237
           PP PPPPPPP PPP  GL     HQ  T+A +      + R  A    V+ N +      
Sbjct: 374 PPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSG 433

Query: 238 MLEILKEM-NSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDE 293
              +L ++   ++L+SV   ++   P P   +     + E ++K+    + SD  ++
Sbjct: 434 RDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDED 490



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 12/18 (66%), Positives = 12/18 (66%), Gaps = 4/18 (22%)

Query: 184 PPHPPP----PPPPLPPP 197
           PP PPP    PPPP PPP
Sbjct: 277 PPPPPPSRGGPPPPPPPP 294



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 3/20 (15%)

Query: 184 PPHPPPPP---PPLPPPALG 200
           PP PPPPP    P PPPA G
Sbjct: 287 PPPPPPPPHNSGPPPPPARG 306


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 15/117 (12%)

Query: 121 PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF 180
           P  +  E +L  P L+ EE +Q +  ++ E+  +  QI+K+  +Q+Q    A        
Sbjct: 153 PPHTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAK------ 206

Query: 181 GTIPPHPPPPPPPL-PPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMP 236
                 PP P  P+ PPP    H+  S V +I +   K+A A   +++    + E+P
Sbjct: 207 ------PPEPEKPVSPPPIESKHR--SLVQIIYDENRKKAEAAHRILEGLGPQVELP 255



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 43/203 (21%), Positives = 72/203 (35%), Gaps = 21/203 (10%)

Query: 113 APSRQISLPDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTA 172
           A S + + P + ++E    +    NEE + +        ++    I    T+  +     
Sbjct: 689 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQN 748

Query: 173 GDLDSTTFGTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKK 232
           G     T G      PPP PP PPP          +    E        G       P  
Sbjct: 749 GPKPPATLGA---DGPPPGPPTPPP--------EDIPAPTEPTPASEATGAPTPPPAPPS 797

Query: 233 PEMPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQD 292
           P  P  + + KE    +  +    E+  + KP  A + A    +A +       +S+  +
Sbjct: 798 PSAPPPV-VPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEP-----VKSECTE 851

Query: 293 EVEKGIPKSE----SEATSERVL 311
           E E+G  K +    +EAT+E  L
Sbjct: 852 EAEEGPAKGKDAEAAEATAEGAL 874


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 15/117 (12%)

Query: 121 PDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLTAGDLDSTTF 180
           P  +  E +L  P L+ EE +Q +  ++ E+  +  QI+K+  +Q+Q    A        
Sbjct: 153 PPHTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAK------ 206

Query: 181 GTIPPHPPPPPPPL-PPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMP 236
                 PP P  P+ PPP    H+  S V +I +   K+A A   +++    + E+P
Sbjct: 207 ------PPEPEKPVSPPPIESKHR--SLVQIIYDENRKKAEAAHRILEGLGPQVELP 255



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 177 STTFGTIPPHPPPPPPPLPPPAL---GLHQSTSAVDLIKERREKRANAGKTLVKNNPKKP 233
           S   G   P P PP P  PPP +      + T+A   ++E  E++  A + L  +  K  
Sbjct: 800 SEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAE 859

Query: 234 E 234
           E
Sbjct: 860 E 860



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 38/145 (26%), Positives = 56/145 (38%), Gaps = 25/145 (17%)

Query: 184 PPHPPPPPP------------------PLPPPALGLHQSTSAVDLIKERREKRANAGKTL 225
           PP PP PPP                  P PPPA     +   V + KE +E+   A   +
Sbjct: 779 PPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPV-VPKEEKEEETAAAPPV 837

Query: 226 VKNNPKKPEMPNMLEI--LKEMNSVKLRSVKRSEQ-DVKPKPVDATDPAALIAEALKKKF 282
            +   +KP     L +   K    VK    + +E+   K K  +A +  A  A   +KK 
Sbjct: 838 EEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKE 897

Query: 283 AYRYRSDSQDEVEKGIPK-SESEAT 306
               R+ +      G P+ S+S AT
Sbjct: 898 GGSGRATTAK--SSGAPQDSDSSAT 920


>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
          Length = 547

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 7/83 (8%)

Query: 183 IPPHPPPPPPPLPPPALGLHQSTSAVDLIKERRE-KRANAGKTLVKNNPKKPEMPNMLEI 241
           +PP PPPPPPPLP   L    + +  ++IK++   +RA       K   K  + PN   I
Sbjct: 438 LPPPPPPPPPPLPEKKL---ITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPN--SI 492

Query: 242 LKEMNSVKLRSVKRSEQDVKPKP 264
           LKE+ +  LRSV+  + +   +P
Sbjct: 493 LKEIKN-SLRSVQEKKMEDSSRP 514


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 15/135 (11%)

Query: 182 TIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLEI 241
           ++PP PPPPPPPLPPP    +   S + +I++R     +  K   K    +PE    +  
Sbjct: 351 SVPP-PPPPPPPLPPPP--PNPIRSLMSMIRKRSHPSGSGAK---KEKATQPETTEEVTD 404

Query: 242 LKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPKS 301
           LK     ++  + R ++ V  +PV+ T      A    K  + +    + DE+ KGI  +
Sbjct: 405 LKRQAVEEM--MDRIKKGVHLRPVNQT------ARPKTKPESSKGCESAVDEL-KGILGT 455

Query: 302 ESEATSERVLVSYLP 316
            +++TS R L S  P
Sbjct: 456 LNKSTSSRSLKSLDP 470


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 34/135 (25%)

Query: 187 PPPPPPPLPPPAL----------------GLHQSTSAVDLIKERREKRANAGKTLVKNNP 230
           PPPPPPPLPPP +                GLH + S            +   + +  + P
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484

Query: 231 KKPEMPNMLEILKEMNSVKLRSVKRS----------EQDVKPKPVDATDPAALIAEALKK 280
           K+   P+ L ++ +  SV L ++++           EQ+ K + ++       +A  L +
Sbjct: 485 KR--HPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIEND-----VATILSR 537

Query: 281 KFAYRYRSDSQDEVE 295
           + A  Y SDS+D+ E
Sbjct: 538 RIAVEY-SDSEDDSE 551



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 29/122 (23%)

Query: 156 AQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPL-------PPPALGLHQSTSAV 208
           +Q+++++T+ E++ L            + PH PPPPPP+       P P       +SA 
Sbjct: 258 SQMSELLTRAEERVL------------VRPHEPPPPPPMHGAGDAKPIPTC----ISSAT 301

Query: 209 DLIKERREKRANAGKTLVKNNPKKPEMPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDAT 268
            LI+ R +  A  G+T V  +P  P  P  L      +++   S++ S     P PV   
Sbjct: 302 GLIENRPQSPA-TGRTPVFVSPTPPPPPPPLP-----SALSTSSLRASMTSTPPPPVPPP 355

Query: 269 DP 270
            P
Sbjct: 356 PP 357



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 11/15 (73%), Positives = 11/15 (73%)

Query: 187 PPPPPPPLPPPALGL 201
           PPP PPP PPPA  L
Sbjct: 349 PPPVPPPPPPPATAL 363



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 14/37 (37%), Positives = 18/37 (48%), Gaps = 9/37 (24%)

Query: 170 LTAGDLDSTTFGTIPPHPPPPPPP---------LPPP 197
           L+   L ++   T PP  PPPPPP         +PPP
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPP 371



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 184 PPHPPPPPPPLPPPAL 199
           PP P PPPPP P  AL
Sbjct: 348 PPPPVPPPPPPPATAL 363


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 34/135 (25%)

Query: 187 PPPPPPPLPPPAL----------------GLHQSTSAVDLIKERREKRANAGKTLVKNNP 230
           PPPPPPPLPPP +                GLH + S            +   + +  + P
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484

Query: 231 KKPEMPNMLEILKEMNSVKLRSVKRS----------EQDVKPKPVDATDPAALIAEALKK 280
           K+   P+ L ++ +  SV L ++++           EQ+ K + ++       +A  L +
Sbjct: 485 KR--HPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIEND-----VATILSR 537

Query: 281 KFAYRYRSDSQDEVE 295
           + A  Y SDS+D+ E
Sbjct: 538 RIAVEY-SDSEDDSE 551



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 29/122 (23%)

Query: 156 AQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPL-------PPPALGLHQSTSAV 208
           +Q+++++T+ E++ L            + PH PPPPPP+       P P       +SA 
Sbjct: 258 SQMSELLTRAEERVL------------VRPHEPPPPPPMHGAGDAKPIPTC----ISSAT 301

Query: 209 DLIKERREKRANAGKTLVKNNPKKPEMPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDAT 268
            LI+ R +  A  G+T V  +P  P  P  L      +++   S++ S     P PV   
Sbjct: 302 GLIENRPQSPA-TGRTPVFVSPTPPPPPPPLP-----SALSTSSLRASMTSTPPPPVPPP 355

Query: 269 DP 270
            P
Sbjct: 356 PP 357



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 11/15 (73%), Positives = 11/15 (73%)

Query: 187 PPPPPPPLPPPALGL 201
           PPP PPP PPPA  L
Sbjct: 349 PPPVPPPPPPPATAL 363



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 14/37 (37%), Positives = 18/37 (48%), Gaps = 9/37 (24%)

Query: 170 LTAGDLDSTTFGTIPPHPPPPPPP---------LPPP 197
           L+   L ++   T PP  PPPPPP         +PPP
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPP 371



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 184 PPHPPPPPPPLPPPAL 199
           PP P PPPPP P  AL
Sbjct: 348 PPPPVPPPPPPPATAL 363


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 34/135 (25%)

Query: 187 PPPPPPPLPPPAL----------------GLHQSTSAVDLIKERREKRANAGKTLVKNNP 230
           PPPPPPPLPPP +                GLH + S            +   + +  + P
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484

Query: 231 KKPEMPNMLEILKEMNSVKLRSVKRS----------EQDVKPKPVDATDPAALIAEALKK 280
           K+   P+ L ++ +  SV L ++++           EQ+ K + ++       +A  L +
Sbjct: 485 KR--HPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIEND-----VATILSR 537

Query: 281 KFAYRYRSDSQDEVE 295
           + A  Y SDS+D+ E
Sbjct: 538 RIAVEY-SDSEDDSE 551



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 29/122 (23%)

Query: 156 AQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPL-------PPPALGLHQSTSAV 208
           +Q+++++T+ E++ L            + PH PPPPPP+       P P       +SA 
Sbjct: 258 SQMSELLTRAEERVL------------VRPHEPPPPPPMHGAGDAKPIPTC----ISSAT 301

Query: 209 DLIKERREKRANAGKTLVKNNPKKPEMPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDAT 268
            LI+ R +  A  G+T V  +P  P  P  L      +++   S++ S     P PV   
Sbjct: 302 GLIENRPQSPA-TGRTPVFVSPTPPPPPPPLP-----SALSTSSLRASMTSTPPPPVPPP 355

Query: 269 DP 270
            P
Sbjct: 356 PP 357



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 11/15 (73%), Positives = 11/15 (73%)

Query: 187 PPPPPPPLPPPALGL 201
           PPP PPP PPPA  L
Sbjct: 349 PPPVPPPPPPPATAL 363



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 14/37 (37%), Positives = 18/37 (48%), Gaps = 9/37 (24%)

Query: 170 LTAGDLDSTTFGTIPPHPPPPPPP---------LPPP 197
           L+   L ++   T PP  PPPPPP         +PPP
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPP 371



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 184 PPHPPPPPPPLPPPAL 199
           PP P PPPPP P  AL
Sbjct: 348 PPPPVPPPPPPPATAL 363


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 34/135 (25%)

Query: 187 PPPPPPPLPPPAL----------------GLHQSTSAVDLIKERREKRANAGKTLVKNNP 230
           PPPPPPPLPPP +                GLH + S            +   + +  + P
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484

Query: 231 KKPEMPNMLEILKEMNSVKLRSVKRS----------EQDVKPKPVDATDPAALIAEALKK 280
           K+   P+ L ++ +  SV L ++++           EQ+ K + ++       +A  L +
Sbjct: 485 KR--HPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIEND-----VATILSR 537

Query: 281 KFAYRYRSDSQDEVE 295
           + A  Y SDS+D+ E
Sbjct: 538 RIAVEY-SDSEDDSE 551



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 29/122 (23%)

Query: 156 AQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPL-------PPPALGLHQSTSAV 208
           +Q+++++T+ E++ L            + PH PPPPPP+       P P       +SA 
Sbjct: 258 SQMSELLTRAEERVL------------VRPHEPPPPPPMHGAGDAKPIPTC----ISSAT 301

Query: 209 DLIKERREKRANAGKTLVKNNPKKPEMPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDAT 268
            LI+ R +  A  G+T V  +P  P  P  L      +++   S++ S     P PV   
Sbjct: 302 GLIENRPQSPA-TGRTPVFVSPTPPPPPPPLP-----SALSTSSLRASMTSTPPPPVPPP 355

Query: 269 DP 270
            P
Sbjct: 356 PP 357



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 11/15 (73%), Positives = 11/15 (73%)

Query: 187 PPPPPPPLPPPALGL 201
           PPP PPP PPPA  L
Sbjct: 349 PPPVPPPPPPPATAL 363



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 14/37 (37%), Positives = 18/37 (48%), Gaps = 9/37 (24%)

Query: 170 LTAGDLDSTTFGTIPPHPPPPPPP---------LPPP 197
           L+   L ++   T PP  PPPPPP         +PPP
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPP 371



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 184 PPHPPPPPPPLPPPAL 199
           PP P PPPPP P  AL
Sbjct: 348 PPPPVPPPPPPPATAL 363


>gi|120587019 zinc finger protein 318 [Homo sapiens]
          Length = 2279

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 34/142 (23%)

Query: 183  IPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLEIL 242
            +PP PPPPPPP PPP +  H +  +          +ANA    VK+NP            
Sbjct: 1441 LPPPPPPPPPPPPPPPVIPHPAAPSA--------AQANAILAPVKSNP------------ 1480

Query: 243  KEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPKSE 302
                   + S   S   V P  ++   P A++A A       +  +   DE   G+ +S+
Sbjct: 1481 -------VVSQTLSPGFVGPNILNPVLPVAIMASA-------QPAAIPSDETAPGVSESD 1526

Query: 303  SEATSERVLVSYLPRFLSCYVE 324
             + T   VLV   P   S + E
Sbjct: 1527 RDQTLFSVLVRPPPPLSSVFSE 1548


>gi|195947369 junction-mediating and regulatory protein [Homo
           sapiens]
          Length = 988

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 5/54 (9%)

Query: 184 PPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPN 237
           PP PPPPPPP PPP L + + +    L K+   K  N      K  PK    P+
Sbjct: 811 PPPPPPPPPPPPPPPLPVAKDSGPETLEKDLPRKEGNE-----KRIPKSASAPS 859


>gi|119120861 formin-like 3 isoform 2 [Homo sapiens]
          Length = 976

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 8/68 (11%)

Query: 138 EEALQKICALENELAALRA----QIAKIVTQQEQQNLTAGDLDSTTFGTIP----PHPPP 189
           EEA Q+ C LE  +  L +     +A++   +  + +   DLD       P    P PPP
Sbjct: 411 EEAFQRRCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPP 470

Query: 190 PPPPLPPP 197
           P PPLPPP
Sbjct: 471 PAPPLPPP 478


>gi|119120874 formin-like 3 isoform 1 [Homo sapiens]
          Length = 1027

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 8/68 (11%)

Query: 138 EEALQKICALENELAALRA----QIAKIVTQQEQQNLTAGDLDSTTFGTIP----PHPPP 189
           EEA Q+ C LE  +  L +     +A++   +  + +   DLD       P    P PPP
Sbjct: 462 EEAFQRRCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPP 521

Query: 190 PPPPLPPP 197
           P PPLPPP
Sbjct: 522 PAPPLPPP 529


>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
          Length = 659

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 35/130 (26%), Positives = 54/130 (41%), Gaps = 6/130 (4%)

Query: 184 PPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLEILK 243
           PP PPPPPPPLPPP+ G       + L    RE+ A  G  L   +P +P  P +     
Sbjct: 22  PPPPPPPPPPLPPPSGGPELEGDGLLL----RERLAALG--LDDPSPAEPGAPALRAPAA 75

Query: 244 EMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVEKGIPKSES 303
                  R+ + S ++  P        AA +     ++       D     E+ + ++E 
Sbjct: 76  AAQGQARRAAELSPEERAPPGRPGAPEAAELELEEDEEEGEEAELDGDLLEEEELEEAEE 135

Query: 304 EATSERVLVS 313
           E  S  +L+S
Sbjct: 136 EDRSSLLLLS 145



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 11/13 (84%), Positives = 11/13 (84%)

Query: 185 PHPPPPPPPLPPP 197
           P PPPPPPP PPP
Sbjct: 19  PQPPPPPPPPPPP 31



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 184 PPHPPPPPPPLPPPAL 199
           P   PPPPPP PPP L
Sbjct: 17  PLPQPPPPPPPPPPPL 32


>gi|13699803 WAS protein family, member 3 [Homo sapiens]
          Length = 502

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/120 (27%), Positives = 54/120 (45%), Gaps = 24/120 (20%)

Query: 182 TIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLEI 241
           T PP P PPPPP  PP  G   S+S +             G  + +   ++P  P + + 
Sbjct: 393 TAPPPPGPPPPPPGPPGPGSSLSSSPMH------------GPPVAEAKRQEPAQPPISDA 440

Query: 242 LKEM-----NSVKLRSV-KRSEQDVKPKPVDATDPAALIAEALKKKFAYRYRSDSQDEVE 295
             ++       ++L+ V ++ EQ+ K +PV        +A  L ++ A  Y SDS D+ E
Sbjct: 441 RSDLLAAIRMGIQLKKVQEQREQEAKREPVGND-----VATILSRRIAVEY-SDSDDDSE 494


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 17/41 (41%), Positives = 22/41 (53%)

Query: 160 KIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPLPPPALG 200
           + + Q  +Q L    +D      +PP PPPPPPP PPP  G
Sbjct: 386 RYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAG 426



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 181 GTIPPHPPPPPPPLPPPALG 200
           G  PP PPPPPPP PPPA G
Sbjct: 408 GLPPPPPPPPPPPPPPPAGG 427



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 14/23 (60%), Positives = 18/23 (78%)

Query: 185 PHPPPPPPPLPPPALGLHQSTSA 207
           P PPPPPPP PPPAL  + +T++
Sbjct: 161 PSPPPPPPPPPPPALSGYTTTNS 183



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 183 IPPHPPPPPPPLPPPALGLHQSTS 206
           +PP P PPPPP PPP   L   T+
Sbjct: 157 LPPTPSPPPPPPPPPPPALSGYTT 180



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 3/47 (6%)

Query: 150 ELAALRAQIAKIVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPLPP 196
           E  A  A+ A +V      +   G   S   G  P  PPPP PPLPP
Sbjct: 116 EAPAAAARAAALVAHPGAGSYPCGGGSS---GAQPSAPPPPAPPLPP 159



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 10/14 (71%), Positives = 10/14 (71%)

Query: 184 PPHPPPPPPPLPPP 197
           PP PP PP P PPP
Sbjct: 152 PPAPPLPPTPSPPP 165



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 10/14 (71%), Positives = 10/14 (71%)

Query: 184 PPHPPPPPPPLPPP 197
           PP PP P PP PPP
Sbjct: 155 PPLPPTPSPPPPPP 168


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 14/125 (11%)

Query: 112 KAPSRQISLPDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAKIVTQQEQQNLT 171
           +APS  IS      ++       L+ EE +Q +  ++ E+A +  QI K+  +Q+Q    
Sbjct: 154 EAPSSPISGQPCGDDQ-NASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEE 212

Query: 172 AGDLDSTTFGTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPK 231
           A              PP P  P+ PP +   +  S V +I +   K+A     + +    
Sbjct: 213 AA------------KPPEPEKPVSPPPVE-QKHRSIVQIIYDENRKKAEEAHKIFEGLGP 259

Query: 232 KPEMP 236
           K E+P
Sbjct: 260 KVELP 264



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 37/143 (25%), Positives = 54/143 (37%), Gaps = 31/143 (21%)

Query: 190 PPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVK---------------------- 227
           PPPPLPPP   +  ST  V+  +   E+   A K LV+                      
Sbjct: 607 PPPPLPPPPEPI--STEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKN 664

Query: 228 ---NNPKKPEMPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAY 284
              N  ++  + N+L+  K+  S K     R E+DV      A+  +A   E ++     
Sbjct: 665 FYFNYKRRHNLDNLLQQHKQKTSRK----PREERDVSQCESVASTVSAQEDEDIEASNEE 720

Query: 285 RYRSDSQDEVEKGIPKSESEATS 307
               DS+ E  K    S   ATS
Sbjct: 721 ENPEDSEVEAVKPSEDSPENATS 743


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 38/154 (24%), Positives = 60/154 (38%), Gaps = 28/154 (18%)

Query: 184 PPHPPPPPPPLPP--------------PALGLHQSTSAVDLIKE----RREKRAN----- 220
           PP PPPPPP LPP              P  G + S+S+  + K+     +E R N     
Sbjct: 116 PPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKN 175

Query: 221 ----AGKTLVKNNPKKPEMPNMLEILKEMNSVKL-RSVKRSEQDVKPKPVDATDPAALIA 275
               AG++    +P  P    +         V+L +    +    +P+ V+  +   L  
Sbjct: 176 SCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTE 235

Query: 276 EALKKKFAYRYRSDSQDEVEKGIPKSESEATSER 309
             +K  F  R     +D+  KGI  S +  + ER
Sbjct: 236 RQIKIWFQNRRMKYKKDQKAKGILHSPASQSPER 269


>gi|50511340 shootin1 isoform b [Homo sapiens]
          Length = 456

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 8/87 (9%)

Query: 182 TIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKRANAGKTLVKNNPKKPEMPNMLEI 241
           ++PP PPPPPPPLPPP    +   S + +I++R     +  K   K    +PE    +  
Sbjct: 351 SVPP-PPPPPPPLPPPP--PNPIRSLMSMIRKRSHPSGSGAK---KEKATQPETTEEVTD 404

Query: 242 LKEMNSVKLRSVKRSEQDVKPKPVDAT 268
           LK     ++  + R ++ V  +PV+ T
Sbjct: 405 LKRQAVEEM--MDRIKKGVHLRPVNQT 429


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 16/27 (59%), Positives = 19/27 (70%)

Query: 183  IPPHPPPPPPPLPPPALGLHQSTSAVD 209
            +P  PPPPPPPLPPP   +   TSAV+
Sbjct: 1544 VPIPPPPPPPPLPPPPPVIKPQTSAVE 1570



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 2/58 (3%)

Query: 180 FGTIPPHPPPPPPPLPPPALGLH-QSTSAVDLIKERREKRANAGKTLVKNNPKKPEMP 236
           +G   P PPP PPP P PAL    Q      ++  +R+         +++ P+ P +P
Sbjct: 97  YGDWQPPPPPMPPP-PGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVP 153


>gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]
          Length = 809

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 39/141 (27%), Positives = 61/141 (43%), Gaps = 21/141 (14%)

Query: 184 PPHPPPPPPPLPPP--ALGLHQSTSAVDLIKER-------------REKRANAGKTLVKN 228
           PP PPP PPP PPP  A G + S+ A   ++ R              ++ + A +T  + 
Sbjct: 75  PPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRP 134

Query: 229 NPKKPEM--PNMLEILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAEALKKKFAYRY 286
             KK  M  P+  + L+  +     S  RS  D    P       A    + +++ ++ Y
Sbjct: 135 GLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRE-SFLY 193

Query: 287 RSDSQDEVEKGIPKSESEATS 307
           RSDS  ++    PKS S  +S
Sbjct: 194 RSDSDYDLS---PKSMSRNSS 211


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,206,356
Number of Sequences: 37866
Number of extensions: 791123
Number of successful extensions: 17505
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 400
Number of HSP's successfully gapped in prelim test: 239
Number of HSP's that attempted gapping in prelim test: 9730
Number of HSP's gapped (non-prelim): 4617
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.