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Search of human proteins with 115387118
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115387118 hypothetical protein LOC57562 [Homo sapiens]
(1117 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115387118 hypothetical protein LOC57562 [Homo sapiens] 2220 0.0
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 50 2e-05
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 49 3e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 47 1e-04
gi|221316624 dystonin isoform 4 [Homo sapiens] 47 1e-04
gi|221316622 dystonin isoform 3 [Homo sapiens] 47 1e-04
gi|221316618 dystonin isoform 2 [Homo sapiens] 47 1e-04
gi|34577047 dystonin isoform 1 [Homo sapiens] 47 1e-04
gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] 47 1e-04
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 47 1e-04
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens] 47 1e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 46 2e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 46 2e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 46 2e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 46 2e-04
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 46 2e-04
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 46 2e-04
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 46 2e-04
gi|55770834 centromere protein F [Homo sapiens] 46 2e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 3e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 3e-04
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 45 3e-04
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 45 4e-04
gi|148746195 trichohyalin [Homo sapiens] 45 5e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 45 5e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 44 7e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 44 7e-04
gi|109134347 NY-REN-58 antigen [Homo sapiens] 44 7e-04
gi|109134355 NY-REN-58 antigen [Homo sapiens] 44 7e-04
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 44 9e-04
>gi|115387118 hypothetical protein LOC57562 [Homo sapiens]
Length = 1117
Score = 2220 bits (5753), Expect = 0.0
Identities = 1117/1117 (100%), Positives = 1117/1117 (100%)
Query: 1 MLAGRPGTRSAVGELGTESSDNLDRAPLGPRESGGHHRPGSYLDMKIHLEKNLEEERQIL 60
MLAGRPGTRSAVGELGTESSDNLDRAPLGPRESGGHHRPGSYLDMKIHLEKNLEEERQIL
Sbjct: 1 MLAGRPGTRSAVGELGTESSDNLDRAPLGPRESGGHHRPGSYLDMKIHLEKNLEEERQIL 60
Query: 61 LQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQR 120
LQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQR
Sbjct: 61 LQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQR 120
Query: 121 AHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALS 180
AHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALS
Sbjct: 121 AHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALS 180
Query: 181 KNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDE 240
KNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDE
Sbjct: 181 KNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDE 240
Query: 241 VNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDK 300
VNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDK
Sbjct: 241 VNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDK 300
Query: 301 LAFSKTQHINNWLTNLDASNTQNVTAFSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERA 360
LAFSKTQHINNWLTNLDASNTQNVTAFSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERA
Sbjct: 301 LAFSKTQHINNWLTNLDASNTQNVTAFSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERA 360
Query: 361 TNTANNSVPFVSSPPMFVLDKKCEKTSETSTMRTTDSTSGAFKRERPLVTESPTFKFSKS 420
TNTANNSVPFVSSPPMFVLDKKCEKTSETSTMRTTDSTSGAFKRERPLVTESPTFKFSKS
Sbjct: 361 TNTANNSVPFVSSPPMFVLDKKCEKTSETSTMRTTDSTSGAFKRERPLVTESPTFKFSKS 420
Query: 421 QSTSDSLTQEVATFPDQEKYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSI 480
QSTSDSLTQEVATFPDQEKYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSI
Sbjct: 421 QSTSDSLTQEVATFPDQEKYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSI 480
Query: 481 HIKEIDAVQCSDKLDELKDGKEEEIKYFNCNKEELPLFSDSFQDAYIPHNPDSKDEKQKL 540
HIKEIDAVQCSDKLDELKDGKEEEIKYFNCNKEELPLFSDSFQDAYIPHNPDSKDEKQKL
Sbjct: 481 HIKEIDAVQCSDKLDELKDGKEEEIKYFNCNKEELPLFSDSFQDAYIPHNPDSKDEKQKL 540
Query: 541 AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFLKSILKKESKYEHGYLKALIINQSFK 600
AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFLKSILKKESKYEHGYLKALIINQSFK
Sbjct: 541 AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFLKSILKKESKYEHGYLKALIINQSFK 600
Query: 601 FGNQKAAAIRDSIELTKEKGAEIPKTIKKLRWFDETSNIENNAENSHSLKNKTGTTQQHS 660
FGNQKAAAIRDSIELTKEKGAEIPKTIKKLRWFDETSNIENNAENSHSLKNKTGTTQQHS
Sbjct: 601 FGNQKAAAIRDSIELTKEKGAEIPKTIKKLRWFDETSNIENNAENSHSLKNKTGTTQQHS 660
Query: 661 QQFHIQSGAGSNIISVSTCAVNSADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYN 720
QQFHIQSGAGSNIISVSTCAVNSADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYN
Sbjct: 661 QQFHIQSGAGSNIISVSTCAVNSADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYN 720
Query: 721 FAKHAWPASKKEESKIPVHDDSKTKQGKPQRGRAKIIRKPGSAKVQSGFICTNRKGAVIQ 780
FAKHAWPASKKEESKIPVHDDSKTKQGKPQRGRAKIIRKPGSAKVQSGFICTNRKGAVIQ
Sbjct: 721 FAKHAWPASKKEESKIPVHDDSKTKQGKPQRGRAKIIRKPGSAKVQSGFICTNRKGAVIQ 780
Query: 781 PQSASKVNIFTQAQGKLIIPCPPPQSTSNIRSGKNIQVSQCQPVTPENPQNIITHNSFNS 840
PQSASKVNIFTQAQGKLIIPCPPPQSTSNIRSGKNIQVSQCQPVTPENPQNIITHNSFNS
Sbjct: 781 PQSASKVNIFTQAQGKLIIPCPPPQSTSNIRSGKNIQVSQCQPVTPENPQNIITHNSFNS 840
Query: 841 KHVLPTEHSLNQWNQESSSPLSNACSDLVTVIPSLPSYCSSECQTFAKINHSNGTQAVAR 900
KHVLPTEHSLNQWNQESSSPLSNACSDLVTVIPSLPSYCSSECQTFAKINHSNGTQAVAR
Sbjct: 841 KHVLPTEHSLNQWNQESSSPLSNACSDLVTVIPSLPSYCSSECQTFAKINHSNGTQAVAR 900
Query: 901 QDATLYCTQRSPVCEESYPSVTLRTAEEESVPLWKRGPNVLHQNKRATGSTVMRRKRIAE 960
QDATLYCTQRSPVCEESYPSVTLRTAEEESVPLWKRGPNVLHQNKRATGSTVMRRKRIAE
Sbjct: 901 QDATLYCTQRSPVCEESYPSVTLRTAEEESVPLWKRGPNVLHQNKRATGSTVMRRKRIAE 960
Query: 961 TKRRNILEQKRQNPGSVGQKYSEQINNFGQSVLLSSSEPKQTTRGTSYIEEVSDSTSEFL 1020
TKRRNILEQKRQNPGSVGQKYSEQINNFGQSVLLSSSEPKQTTRGTSYIEEVSDSTSEFL
Sbjct: 961 TKRRNILEQKRQNPGSVGQKYSEQINNFGQSVLLSSSEPKQTTRGTSYIEEVSDSTSEFL 1020
Query: 1021 MAENLVKASVPEDEILTVLNSKQIQKSNLPLNKTQQFNICTLSAEEQKILESLNDLSERL 1080
MAENLVKASVPEDEILTVLNSKQIQKSNLPLNKTQQFNICTLSAEEQKILESLNDLSERL
Sbjct: 1021 MAENLVKASVPEDEILTVLNSKQIQKSNLPLNKTQQFNICTLSAEEQKILESLNDLSERL 1080
Query: 1081 HYIQESICKNPSIKNTLQIIPLLEKREDRTSSCRDKR 1117
HYIQESICKNPSIKNTLQIIPLLEKREDRTSSCRDKR
Sbjct: 1081 HYIQESICKNPSIKNTLQIIPLLEKREDRTSSCRDKR 1117
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 49.7 bits (117), Expect = 2e-05
Identities = 106/546 (19%), Positives = 212/546 (38%), Gaps = 69/546 (12%)
Query: 42 YLDMKIHLEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIRE 101
Y D+K EK + ++QI Q+++ R + R K EK+K Q +E +++
Sbjct: 1245 YADLK---EKLTDAKKQIKQVQKEVSVMRDEDKLL---RIKINELEKKKNQCSQELDMKQ 1298
Query: 102 QILQQRK-----QKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEV 156
+ +QQ K QK EE ++++RA L+ + K + + E+ Q+++ +
Sbjct: 1299 RTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAK 1358
Query: 157 NLPFSRRPT--INWRAIDSALP---SALSKNDHKHQKQLLSKI-NCEKEMNENMRATLAT 210
R T W+ + L + S +H++ +L K+ N + E+ E+ + A
Sbjct: 1359 LEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 1418
Query: 211 SKNVFQLKLEETQKLLEDQHLSN--LQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTL 268
K + K+ + E +++ N ++K+ ++ + + I + + TE +
Sbjct: 1419 RKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKW 1478
Query: 269 NKEHSTSIQRNTISLK---PANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVT 325
+E + I LK +N+Q N ++ K S+T I + +D + +
Sbjct: 1479 REERDQLVAALEIQLKALISSNVQKDNE--IEQLKRIISETSKIETQI--MDIKPKRISS 1534
Query: 326 AFSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEK 385
A D L + S+E +K ++ S + + E +T D+
Sbjct: 1535 ADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTEN----------------DQSTRF 1578
Query: 386 TSETSTMRTTDSTSGAFKRERPLVTESPTFKFSKSQSTSDSLTQEVATFPDQEKYSELNQ 445
++ T + P T T K K++ + +E D K
Sbjct: 1579 PKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEE-----DLVKCENKKN 1633
Query: 446 ENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSIHIKEIDAVQCSDKLDELKDGKEEEI 505
T++ V + RPS+K + ++ ++ + + K+G
Sbjct: 1634 ATPRTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEG----- 1688
Query: 506 KYFNCNKEELPLFSDSFQDAYIPHNPDSKDEK-QKLAET---SSLSNVTSNYDFVGQHKK 561
L F D ++ H+P K +K+ ET S LSNV ++ + V Q K+
Sbjct: 1689 --------TLQKFGD-----FLQHSPSILQSKAKKIIETMSSSKLSNVEASKENVSQPKR 1735
Query: 562 MKYNIH 567
K ++
Sbjct: 1736 AKRKLY 1741
Score = 42.7 bits (99), Expect = 0.002
Identities = 138/664 (20%), Positives = 265/664 (39%), Gaps = 78/664 (11%)
Query: 40 GSYLDMKIHLEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQI 99
G + K L+K E E L+Q+ + + K + N+R K E ++KE I
Sbjct: 689 GELIKTKEELKKR-ENESDSLIQELET----SNKKIITQNQRIK---ELINIIDQKEDTI 740
Query: 100 RE-QILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEAL-----KQIQESNLK 153
E Q L+ + + +K + + ++ + VP ++ K++ E+ L+
Sbjct: 741 NEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICSERKRVNENELQ 800
Query: 154 SEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQL-LSKINCEKEMNENMRATLATSK 212
+ P +++ +I+ + SA+ K++ + I +E NE +RA L T +
Sbjct: 801 QDE--PPAKKGSIH---VSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLTIE 855
Query: 213 NVFQLKLEETQKLLE-----DQHLSNLQK----FGDEVNQITNSETLS----SIDSLEAT 259
N + + EE +L + Q LS +K EV QI ++ ++ + +
Sbjct: 856 NELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQ 915
Query: 260 EHEEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDAS 319
E EE + L+ E T+ + T ++ + T + DE + S +Q ++N+D
Sbjct: 916 EQEEKIMKLSNEIETATRSITNNVSQIKLMHTKI---DELRTLDSVSQ-----ISNIDLL 967
Query: 320 NTQNVTAFSDILSKSNV---LPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSSPPM 376
N ++++ S+ + N L +Y SK+ E N F SS +
Sbjct: 968 NLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQ--------VKEYRIQEPNRENSFHSS--I 1017
Query: 377 FVLDKKCEKTSETSTMRTTDSTSGAFKRERPLVTESPTFK------FSKSQSTSDSLTQE 430
+ ++C++ + S+ ++ + E+ L E +K K D L +E
Sbjct: 1018 EAIWEECKEIVKASSKKSHQIEELEQQIEK-LQAEVKGYKDENNRLKEKEHKNQDDLLKE 1076
Query: 431 VATFPDQEKYSELNQENGTTSIPTSCVPVATPLV--LPSNIQSARPSAKNSIHIKEIDAV 488
T Q K EL ++N T + V + L + + K I E V
Sbjct: 1077 KETLIQQLK-EELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKV 1135
Query: 489 QCSDKLDELKDGKEEEIKYFNCNKEELPLFSDSFQDAYIPHNPDSKDEKQKLAETSSLSN 548
+CS +D E+E + L F + QD+ + + D ++ KL E ++
Sbjct: 1136 ECSHSAKLEQDILEKESIILKLER-NLKEFQEHLQDS-VKNTKDLNVKELKLKE--EITQ 1191
Query: 549 VTSNYDFVGQHKKMKYNIHERNGVRFLKSILKKESKYEHGYLKALIINQSFKFGNQKAAA 608
+T+N + ++K E N K LK+E + L + K + A
Sbjct: 1192 LTNNLQDMKHLLQLKEEEEETNRQETEK--LKEELSASSARTQNLKADLQRK--EEDYAD 1247
Query: 609 IRDSIELTKEKGAEIPKTIKKLRWFDETSNIENNA------ENSHSLKNKTGTTQQHSQQ 662
+++ + K++ ++ K + +R D+ I+ N + S L K T QQ +Q
Sbjct: 1248 LKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQ 1307
Query: 663 FHIQ 666
+ Q
Sbjct: 1308 LNNQ 1311
Score = 32.3 bits (72), Expect = 2.6
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 16/117 (13%)
Query: 49 LEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQ--- 105
L+K LEE + + ++K RK KK ++KE+ E +IRE++ Q
Sbjct: 557 LDKTLEENKAFISHEEK------RKLLDLIEDLKKKLINEKKEKLTLEFKIREEVTQEFT 610
Query: 106 ----QRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPV---PPLEEALKQIQESNLKSE 155
QR+ F+E + + ++RR A+ + V EEA K I + +++E
Sbjct: 611 QYWAQREADFKETLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICATKVETE 667
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 48.9 bits (115), Expect = 3e-05
Identities = 60/242 (24%), Positives = 108/242 (44%), Gaps = 38/242 (15%)
Query: 49 LEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRK 108
+E+ L++ Q + K ++ F+ES ++ EEK K+ + ++E + Q +
Sbjct: 334 IEQQLDDVHQ--KEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNECDHLKESLFQYER 391
Query: 109 QKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINW 168
+K E V V Q+ A S K + LE L+ I + +NL ++ P
Sbjct: 392 EKAERVVV------VRQLQQEAADSLKKLTMLESPLEGISHYH----INLDETQVPKKKL 441
Query: 169 RAIDSALPSALSKNDHKHQKQLLSK--INCEKEMNENMRATLATSKNVFQ--LKLEETQK 224
++S +D +K+ +S +N KE+ + + L + K V Q KLEE +K
Sbjct: 442 FQVESQF------DDFMAEKEAVSSKCVNLAKEI-QVFQQELLSMKKVQQECEKLEEDKK 494
Query: 225 LLEDQ-------------HLSNLQKFGDEVNQ--ITNSETLSSIDSLEATEHEEIYLTLN 269
+LE++ LS LQ++ E+++ + E L I E EH++ LN
Sbjct: 495 MLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQLEQLN 554
Query: 270 KE 271
K+
Sbjct: 555 KD 556
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 47.0 bits (110), Expect = 1e-04
Identities = 63/329 (19%), Positives = 127/329 (38%), Gaps = 16/329 (4%)
Query: 232 SNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPANMQST 291
SN D + +S++ SS DS +++ + + N S+ ++ S + S+
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Query: 292 NLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTAFSDILSKSNVLPSWEYFNSKEQNPS 351
N + D D S + +N + D+S++ N + SD SN S + +S + + S
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Query: 352 PLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKTSETSTMRTTDSTSGAFKRERPLVTE 411
+ ++N++++S SS + ++ + + ++DS+
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSS----------DSSNSSDSSDSSDSSDSDSSNSSDSSNS 829
Query: 412 SPTFKFSKSQSTSDSLTQEVATFPDQEKYSELNQENGTTSIPTSCVPVATPLVLPSNIQS 471
S + S S +SDS + D S+ + + ++ S + SN S
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Query: 472 ARPSAKNSIHIKEIDAVQCSDKLD-----ELKDGKEEEIKYFNCNKEELPLFSDSFQDAY 526
+ +S + + D+ S+ D D E N N + SDS +
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Query: 527 IPHNPDSKDEKQKL-AETSSLSNVTSNYD 554
++ DS + + SS SN + + D
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978
Score = 31.6 bits (70), Expect = 4.4
Identities = 59/326 (18%), Positives = 131/326 (40%), Gaps = 32/326 (9%)
Query: 227 EDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPA 286
+D S+ K + + +S++ +S DS ++++ + + + +S ++ S
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594
Query: 287 NMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTAFSDILSKSNVLPSWEYFNSK 346
+ S+N S + + + ++ + D+S +++ ++ SD SKS+ S NS
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD--SKSDSSDS----NSS 648
Query: 347 EQNPSPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKTSETSTMRTTDSTSGAFKRER 406
+ + + + ++N++++S SS + +S + + ++DS+ +
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSS----------DSSSSSDSSNSSDSSDSSDSSNS 698
Query: 407 PLVTESPTFKFSKSQSTSDSLTQEVATFPDQEKYSELNQENGTTSIPTSCVPVATPLVLP 466
++S S S +SDS S+ + N + S +S ++
Sbjct: 699 SESSDSSDSSDSDSSDSSDS---------SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749
Query: 467 SNIQSARPSAKNSIHIKEIDAVQCSDKLDELKDGKEEEIKYFNCNKEELPLFSDSFQDAY 526
SN + S+ +S D+ SD D + + N + SDS +
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND----SSNSSD---SSDSSNSSD 802
Query: 527 IPHNPDSKDEKQKLAETSSLSNVTSN 552
++ DS D SS S+ +SN
Sbjct: 803 SSNSSDSSDSSDSSDSDSSNSSDSSN 828
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 47.0 bits (110), Expect = 1e-04
Identities = 152/786 (19%), Positives = 299/786 (38%), Gaps = 133/786 (16%)
Query: 50 EKNLEEERQILLQQQKICR--NRARKYFVESNRRKKAFEEKRKEQEE---------KEHQ 98
E L EE ++ + I + +++ E + +++ F E ++ K ++
Sbjct: 1221 ETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYK 1280
Query: 99 IREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVS---------RKPVPPLEEALKQIQE 149
R+ K+K +++ E++Q HV + R + + R PL++ ++Q++
Sbjct: 1281 ERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVET 1340
Query: 150 SNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINC-EKEMNENMRATL 208
+ K + N P + + L + L++ QK L+S+I + +M+E +
Sbjct: 1341 TQRKIQENQPENSK----------TLATQLNQ-----QKMLVSEIEMKQSKMDECQKYAE 1385
Query: 209 ATSKNV--FQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYL 266
S V ++L+ + +++ Q S +++ ++ +S L + ++ +
Sbjct: 1386 QYSATVKDYELQTMTYRAMVDSQQKSPVKR-----RRMQSSADLIIQEFMDLRTRYTALV 1440
Query: 267 TLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTA 326
TL ++ I+ SLK ++ S +E K K + + W++N+ + A
Sbjct: 1441 TLMTQY---IKFAGDSLK--RLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKA 1495
Query: 327 FSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKT 386
SK + S E ++K++ S T++ + ++ L+K+ +
Sbjct: 1496 GKPPFSKQKI--SSEEISTKKEQLSEALQTIQLFLAKHGDK---MTDEERNELEKQVKTL 1550
Query: 387 SETSTMRTTDS--------TSGAFKRERPLVTESPTFKFSKSQSTSDSLTQ-EVATFPDQ 437
E+ + ++S TSG K E +V E K Q D LTQ E Q
Sbjct: 1551 QESYNLLFSESLKQLQESQTSGDVKVEEKIVAERQQEYKEKLQGICDLLTQTENRLIGHQ 1610
Query: 438 E-----------KYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSIHIKEID 486
E K + QE + S +A + N +N + + D
Sbjct: 1611 EAFMIGDGTVELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLK-----ENGEKLSQED 1665
Query: 487 AVQCSDKLDELKDGKEEEIKYFNCNKEEL------PLFSDSFQDAYIPHNPDSKDEKQKL 540
KL+E K E+ +K+EL + ++ + A + +SK + + L
Sbjct: 1666 KALIEQKLNEAKIKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKIENL 1725
Query: 541 AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFL----KSILKKESKYEHGYLKALI-- 594
+ LSNV + + G K + E+NG F KS + +E + L+ +
Sbjct: 1726 LDW--LSNVDKDSERAGTKHK---QVIEQNGTHFQEGDGKSAIGEEDEVNGNLLETDVDG 1780
Query: 595 --------INQSF--------KFGNQKAAAI-----------RDSIELTKEKGAEIPKTI 627
+NQ + K +Q A I + L+ E+ ++ K +
Sbjct: 1781 QVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQVLLEKQGQYLSPEEKEKLQKNM 1840
Query: 628 KKLRWFDET--SNIENNAENSHSLKNKTGTTQQHSQQFH---IQSGAGSNIISVSTCAVN 682
K+L+ ET + E + +HSL+ + +F QS + +N
Sbjct: 1841 KELKVHYETALAESEKKMKLTHSLQEELEKFDADYTEFEHWLQQSEQELENLEAGADDIN 1900
Query: 683 SADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYNFAKHAWPASKKEESKIPVHDDS 742
TK R+ S SE+V + G L SG + A SK++ K+
Sbjct: 1901 GLMTKLKRQKSFSEDVISHKGD------LRYITISGNRVLEAAKSCSKRDGGKVDTSATH 1954
Query: 743 KTKQGK 748
+ Q K
Sbjct: 1955 REVQRK 1960
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 47.0 bits (110), Expect = 1e-04
Identities = 152/786 (19%), Positives = 299/786 (38%), Gaps = 133/786 (16%)
Query: 50 EKNLEEERQILLQQQKICR--NRARKYFVESNRRKKAFEEKRKEQEE---------KEHQ 98
E L EE ++ + I + +++ E + +++ F E ++ K ++
Sbjct: 1232 ETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYK 1291
Query: 99 IREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVS---------RKPVPPLEEALKQIQE 149
R+ K+K +++ E++Q HV + R + + R PL++ ++Q++
Sbjct: 1292 ERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVET 1351
Query: 150 SNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINC-EKEMNENMRATL 208
+ K + N P + + L + L++ QK L+S+I + +M+E +
Sbjct: 1352 TQRKIQENQPENSK----------TLATQLNQ-----QKMLVSEIEMKQSKMDECQKYAE 1396
Query: 209 ATSKNV--FQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYL 266
S V ++L+ + +++ Q S +++ ++ +S L + ++ +
Sbjct: 1397 QYSATVKDYELQTMTYRAMVDSQQKSPVKR-----RRMQSSADLIIQEFMDLRTRYTALV 1451
Query: 267 TLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTA 326
TL ++ I+ SLK ++ S +E K K + + W++N+ + A
Sbjct: 1452 TLMTQY---IKFAGDSLK--RLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKA 1506
Query: 327 FSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKT 386
SK + S E ++K++ S T++ + ++ L+K+ +
Sbjct: 1507 GKPPFSKQKI--SSEEISTKKEQLSEALQTIQLFLAKHGDK---MTDEERNELEKQVKTL 1561
Query: 387 SETSTMRTTDS--------TSGAFKRERPLVTESPTFKFSKSQSTSDSLTQ-EVATFPDQ 437
E+ + ++S TSG K E +V E K Q D LTQ E Q
Sbjct: 1562 QESYNLLFSESLKQLQESQTSGDVKVEEKIVAERQQEYKEKLQGICDLLTQTENRLIGHQ 1621
Query: 438 E-----------KYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSIHIKEID 486
E K + QE + S +A + N +N + + D
Sbjct: 1622 EAFMIGDGTVELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLK-----ENGEKLSQED 1676
Query: 487 AVQCSDKLDELKDGKEEEIKYFNCNKEEL------PLFSDSFQDAYIPHNPDSKDEKQKL 540
KL+E K E+ +K+EL + ++ + A + +SK + + L
Sbjct: 1677 KALIEQKLNEAKIKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKIENL 1736
Query: 541 AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFL----KSILKKESKYEHGYLKALI-- 594
+ LSNV + + G K + E+NG F KS + +E + L+ +
Sbjct: 1737 LDW--LSNVDKDSERAGTKHK---QVIEQNGTHFQEGDGKSAIGEEDEVNGNLLETDVDG 1791
Query: 595 --------INQSF--------KFGNQKAAAI-----------RDSIELTKEKGAEIPKTI 627
+NQ + K +Q A I + L+ E+ ++ K +
Sbjct: 1792 QVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQVLLEKQGQYLSPEEKEKLQKNM 1851
Query: 628 KKLRWFDET--SNIENNAENSHSLKNKTGTTQQHSQQFH---IQSGAGSNIISVSTCAVN 682
K+L+ ET + E + +HSL+ + +F QS + +N
Sbjct: 1852 KELKVHYETALAESEKKMKLTHSLQEELEKFDADYTEFEHWLQQSEQELENLEAGADDIN 1911
Query: 683 SADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYNFAKHAWPASKKEESKIPVHDDS 742
TK R+ S SE+V + G L SG + A SK++ K+
Sbjct: 1912 GLMTKLKRQKSFSEDVISHKGD------LRYITISGNRVLEAAKSCSKRDGGKVDTSATH 1965
Query: 743 KTKQGK 748
+ Q K
Sbjct: 1966 REVQRK 1971
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 47.0 bits (110), Expect = 1e-04
Identities = 152/786 (19%), Positives = 299/786 (38%), Gaps = 133/786 (16%)
Query: 50 EKNLEEERQILLQQQKICR--NRARKYFVESNRRKKAFEEKRKEQEE---------KEHQ 98
E L EE ++ + I + +++ E + +++ F E ++ K ++
Sbjct: 1370 ETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYK 1429
Query: 99 IREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVS---------RKPVPPLEEALKQIQE 149
R+ K+K +++ E++Q HV + R + + R PL++ ++Q++
Sbjct: 1430 ERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVET 1489
Query: 150 SNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINC-EKEMNENMRATL 208
+ K + N P + + L + L++ QK L+S+I + +M+E +
Sbjct: 1490 TQRKIQENQPENSK----------TLATQLNQ-----QKMLVSEIEMKQSKMDECQKYAE 1534
Query: 209 ATSKNV--FQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYL 266
S V ++L+ + +++ Q S +++ ++ +S L + ++ +
Sbjct: 1535 QYSATVKDYELQTMTYRAMVDSQQKSPVKR-----RRMQSSADLIIQEFMDLRTRYTALV 1589
Query: 267 TLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTA 326
TL ++ I+ SLK ++ S +E K K + + W++N+ + A
Sbjct: 1590 TLMTQY---IKFAGDSLK--RLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKA 1644
Query: 327 FSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKT 386
SK + S E ++K++ S T++ + ++ L+K+ +
Sbjct: 1645 GKPPFSKQKI--SSEEISTKKEQLSEALQTIQLFLAKHGDK---MTDEERNELEKQVKTL 1699
Query: 387 SETSTMRTTDS--------TSGAFKRERPLVTESPTFKFSKSQSTSDSLTQ-EVATFPDQ 437
E+ + ++S TSG K E +V E K Q D LTQ E Q
Sbjct: 1700 QESYNLLFSESLKQLQESQTSGDVKVEEKIVAERQQEYKEKLQGICDLLTQTENRLIGHQ 1759
Query: 438 E-----------KYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSIHIKEID 486
E K + QE + S +A + N +N + + D
Sbjct: 1760 EAFMIGDGTVELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLK-----ENGEKLSQED 1814
Query: 487 AVQCSDKLDELKDGKEEEIKYFNCNKEEL------PLFSDSFQDAYIPHNPDSKDEKQKL 540
KL+E K E+ +K+EL + ++ + A + +SK + + L
Sbjct: 1815 KALIEQKLNEAKIKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKIENL 1874
Query: 541 AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFL----KSILKKESKYEHGYLKALI-- 594
+ LSNV + + G K + E+NG F KS + +E + L+ +
Sbjct: 1875 LDW--LSNVDKDSERAGTKHK---QVIEQNGTHFQEGDGKSAIGEEDEVNGNLLETDVDG 1929
Query: 595 --------INQSF--------KFGNQKAAAI-----------RDSIELTKEKGAEIPKTI 627
+NQ + K +Q A I + L+ E+ ++ K +
Sbjct: 1930 QVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQVLLEKQGQYLSPEEKEKLQKNM 1989
Query: 628 KKLRWFDET--SNIENNAENSHSLKNKTGTTQQHSQQFH---IQSGAGSNIISVSTCAVN 682
K+L+ ET + E + +HSL+ + +F QS + +N
Sbjct: 1990 KELKVHYETALAESEKKMKLTHSLQEELEKFDADYTEFEHWLQQSEQELENLEAGADDIN 2049
Query: 683 SADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYNFAKHAWPASKKEESKIPVHDDS 742
TK R+ S SE+V + G L SG + A SK++ K+
Sbjct: 2050 GLMTKLKRQKSFSEDVISHKGD------LRYITISGNRVLEAAKSCSKRDGGKVDTSATH 2103
Query: 743 KTKQGK 748
+ Q K
Sbjct: 2104 REVQRK 2109
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 47.0 bits (110), Expect = 1e-04
Identities = 152/786 (19%), Positives = 299/786 (38%), Gaps = 133/786 (16%)
Query: 50 EKNLEEERQILLQQQKICR--NRARKYFVESNRRKKAFEEKRKEQEE---------KEHQ 98
E L EE ++ + I + +++ E + +++ F E ++ K ++
Sbjct: 1192 ETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYK 1251
Query: 99 IREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVS---------RKPVPPLEEALKQIQE 149
R+ K+K +++ E++Q HV + R + + R PL++ ++Q++
Sbjct: 1252 ERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVET 1311
Query: 150 SNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINC-EKEMNENMRATL 208
+ K + N P + + L + L++ QK L+S+I + +M+E +
Sbjct: 1312 TQRKIQENQPENSK----------TLATQLNQ-----QKMLVSEIEMKQSKMDECQKYAE 1356
Query: 209 ATSKNV--FQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYL 266
S V ++L+ + +++ Q S +++ ++ +S L + ++ +
Sbjct: 1357 QYSATVKDYELQTMTYRAMVDSQQKSPVKR-----RRMQSSADLIIQEFMDLRTRYTALV 1411
Query: 267 TLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTA 326
TL ++ I+ SLK ++ S +E K K + + W++N+ + A
Sbjct: 1412 TLMTQY---IKFAGDSLK--RLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKA 1466
Query: 327 FSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKT 386
SK + S E ++K++ S T++ + ++ L+K+ +
Sbjct: 1467 GKPPFSKQKI--SSEEISTKKEQLSEALQTIQLFLAKHGDK---MTDEERNELEKQVKTL 1521
Query: 387 SETSTMRTTDS--------TSGAFKRERPLVTESPTFKFSKSQSTSDSLTQ-EVATFPDQ 437
E+ + ++S TSG K E +V E K Q D LTQ E Q
Sbjct: 1522 QESYNLLFSESLKQLQESQTSGDVKVEEKIVAERQQEYKEKLQGICDLLTQTENRLIGHQ 1581
Query: 438 E-----------KYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSIHIKEID 486
E K + QE + S +A + N +N + + D
Sbjct: 1582 EAFMIGDGTVELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLK-----ENGEKLSQED 1636
Query: 487 AVQCSDKLDELKDGKEEEIKYFNCNKEEL------PLFSDSFQDAYIPHNPDSKDEKQKL 540
KL+E K E+ +K+EL + ++ + A + +SK + + L
Sbjct: 1637 KALIEQKLNEAKIKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKIENL 1696
Query: 541 AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFL----KSILKKESKYEHGYLKALI-- 594
+ LSNV + + G K + E+NG F KS + +E + L+ +
Sbjct: 1697 LDW--LSNVDKDSERAGTKHK---QVIEQNGTHFQEGDGKSAIGEEDEVNGNLLETDVDG 1751
Query: 595 --------INQSF--------KFGNQKAAAI-----------RDSIELTKEKGAEIPKTI 627
+NQ + K +Q A I + L+ E+ ++ K +
Sbjct: 1752 QVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQVLLEKQGQYLSPEEKEKLQKNM 1811
Query: 628 KKLRWFDET--SNIENNAENSHSLKNKTGTTQQHSQQFH---IQSGAGSNIISVSTCAVN 682
K+L+ ET + E + +HSL+ + +F QS + +N
Sbjct: 1812 KELKVHYETALAESEKKMKLTHSLQEELEKFDADYTEFEHWLQQSEQELENLEAGADDIN 1871
Query: 683 SADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYNFAKHAWPASKKEESKIPVHDDS 742
TK R+ S SE+V + G L SG + A SK++ K+
Sbjct: 1872 GLMTKLKRQKSFSEDVISHKGD------LRYITISGNRVLEAAKSCSKRDGGKVDTSATH 1925
Query: 743 KTKQGK 748
+ Q K
Sbjct: 1926 REVQRK 1931
>gi|34577049 dystonin isoform 1eA precursor [Homo sapiens]
Length = 5171
Score = 47.0 bits (110), Expect = 1e-04
Identities = 152/786 (19%), Positives = 299/786 (38%), Gaps = 133/786 (16%)
Query: 50 EKNLEEERQILLQQQKICR--NRARKYFVESNRRKKAFEEKRKEQEE---------KEHQ 98
E L EE ++ + I + +++ E + +++ F E ++ K ++
Sbjct: 866 ETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYK 925
Query: 99 IREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVS---------RKPVPPLEEALKQIQE 149
R+ K+K +++ E++Q HV + R + + R PL++ ++Q++
Sbjct: 926 ERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVET 985
Query: 150 SNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINC-EKEMNENMRATL 208
+ K + N P + + L + L++ QK L+S+I + +M+E +
Sbjct: 986 TQRKIQENQPENSK----------TLATQLNQ-----QKMLVSEIEMKQSKMDECQKYAE 1030
Query: 209 ATSKNV--FQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYL 266
S V ++L+ + +++ Q S +++ ++ +S L + ++ +
Sbjct: 1031 QYSATVKDYELQTMTYRAMVDSQQKSPVKR-----RRMQSSADLIIQEFMDLRTRYTALV 1085
Query: 267 TLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTA 326
TL ++ I+ SLK ++ S +E K K + + W++N+ + A
Sbjct: 1086 TLMTQY---IKFAGDSLK--RLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKA 1140
Query: 327 FSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKT 386
SK + S E ++K++ S T++ + ++ L+K+ +
Sbjct: 1141 GKPPFSKQKI--SSEEISTKKEQLSEALQTIQLFLAKHGDK---MTDEERNELEKQVKTL 1195
Query: 387 SETSTMRTTDS--------TSGAFKRERPLVTESPTFKFSKSQSTSDSLTQ-EVATFPDQ 437
E+ + ++S TSG K E +V E K Q D LTQ E Q
Sbjct: 1196 QESYNLLFSESLKQLQESQTSGDVKVEEKIVAERQQEYKEKLQGICDLLTQTENRLIGHQ 1255
Query: 438 E-----------KYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSIHIKEID 486
E K + QE + S +A + N +N + + D
Sbjct: 1256 EAFMIGDGTVELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLK-----ENGEKLSQED 1310
Query: 487 AVQCSDKLDELKDGKEEEIKYFNCNKEEL------PLFSDSFQDAYIPHNPDSKDEKQKL 540
KL+E K E+ +K+EL + ++ + A + +SK + + L
Sbjct: 1311 KALIEQKLNEAKIKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKIENL 1370
Query: 541 AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFL----KSILKKESKYEHGYLKALI-- 594
+ LSNV + + G K + E+NG F KS + +E + L+ +
Sbjct: 1371 LDW--LSNVDKDSERAGTKHK---QVIEQNGTHFQEGDGKSAIGEEDEVNGNLLETDVDG 1425
Query: 595 --------INQSF--------KFGNQKAAAI-----------RDSIELTKEKGAEIPKTI 627
+NQ + K +Q A I + L+ E+ ++ K +
Sbjct: 1426 QVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQVLLEKQGQYLSPEEKEKLQKNM 1485
Query: 628 KKLRWFDET--SNIENNAENSHSLKNKTGTTQQHSQQFH---IQSGAGSNIISVSTCAVN 682
K+L+ ET + E + +HSL+ + +F QS + +N
Sbjct: 1486 KELKVHYETALAESEKKMKLTHSLQEELEKFDADYTEFEHWLQQSEQELENLEAGADDIN 1545
Query: 683 SADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYNFAKHAWPASKKEESKIPVHDDS 742
TK R+ S SE+V + G L SG + A SK++ K+
Sbjct: 1546 GLMTKLKRQKSFSEDVISHKGD------LRYITISGNRVLEAAKSCSKRDGGKVDTSATH 1599
Query: 743 KTKQGK 748
+ Q K
Sbjct: 1600 REVQRK 1605
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 47.0 bits (110), Expect = 1e-04
Identities = 36/137 (26%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Query: 65 KICRNRARKYFVE--SNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAH 122
KI AR+Y V+ SN+ ++A+ +++ +E K H+ E++L + ++ +EK Q+
Sbjct: 299 KINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEK-QKIR 357
Query: 123 VPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKN 182
P QR +A + E+ALK +E ++ + ++P A+ A S SK
Sbjct: 358 KPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPE---EALSQAKKSVASKT 414
Query: 183 DHKHQKQLLSKINCEKE 199
+ K ++ S +N + E
Sbjct: 415 EVKKTRRPRSVLNTQPE 431
>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
Length = 645
Score = 47.0 bits (110), Expect = 1e-04
Identities = 36/137 (26%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Query: 65 KICRNRARKYFVE--SNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAH 122
KI AR+Y V+ SN+ ++A+ +++ +E K H+ E++L + ++ +EK Q+
Sbjct: 299 KINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEK-QKIR 357
Query: 123 VPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKN 182
P QR +A + E+ALK +E ++ + ++P A+ A S SK
Sbjct: 358 KPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPE---EALSQAKKSVASKT 414
Query: 183 DHKHQKQLLSKINCEKE 199
+ K ++ S +N + E
Sbjct: 415 EVKKTRRPRSVLNTQPE 431
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/246 (21%), Positives = 106/246 (43%), Gaps = 31/246 (12%)
Query: 39 PGSYLDMKIHLEK----NLEEERQILL------QQQKICRNRARKYFVESNRRKKAFEEK 88
PG L+ LEK LE+ER+ ++++ + R+ E RR++ E K
Sbjct: 713 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 772
Query: 89 RKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQ 148
R+E+EE + +E+ L R+Q+ +E+ + QR Q+ +A+ R LEE ++ +
Sbjct: 773 RREEEELARRKQEEAL--RRQREQEIALRRQREEEERQQQEEALRR-----LEERRRE-E 824
Query: 149 ESNLKSEVNLPFSRRPTINWRAIDSALPSALSKN-----------DHKHQKQLLSKINCE 197
E K E L W + L +N H+ +++ ++ +
Sbjct: 825 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
Query: 198 KEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQIT-NSETLSSIDSL 256
++ E MR + + +L+ ++ Q+ L L + +G + N S+ S+ +
Sbjct: 885 RQ-KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 943
Query: 257 EATEHE 262
+ E E
Sbjct: 944 QKLEEE 949
Score = 40.8 bits (94), Expect = 0.007
Identities = 44/200 (22%), Positives = 92/200 (46%), Gaps = 22/200 (11%)
Query: 50 EKNLEEERQILLQQQKICRNR------ARKYFVESNRRKKAFE-EKRKEQEEKEHQIREQ 102
E+ ++ +IL +QQ+ R R AR+ E+ RR++ E R+++EE+E Q +E+
Sbjct: 753 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
Query: 103 ILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSR 162
L++ +++ E E+ R L ++++ + K EEA ++++E+ L+ E R
Sbjct: 813 ALRRLEERRREEEER--RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR 870
Query: 163 RPTINWRAIDSALP-------------SALSKNDHKHQKQLLSKINCEKEMNENMRATLA 209
+ + + AL + + Q+Q L+++ ++
Sbjct: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 930
Query: 210 TSKNVFQLKLEETQKLLEDQ 229
++ L L E QKL E++
Sbjct: 931 ACQSQATLSLAEIQKLEEER 950
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/246 (21%), Positives = 106/246 (43%), Gaps = 31/246 (12%)
Query: 39 PGSYLDMKIHLEK----NLEEERQILL------QQQKICRNRARKYFVESNRRKKAFEEK 88
PG L+ LEK LE+ER+ ++++ + R+ E RR++ E K
Sbjct: 740 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 799
Query: 89 RKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQ 148
R+E+EE + +E+ L R+Q+ +E+ + QR Q+ +A+ R LEE ++ +
Sbjct: 800 RREEEELARRKQEEAL--RRQREQEIALRRQREEEERQQQEEALRR-----LEERRRE-E 851
Query: 149 ESNLKSEVNLPFSRRPTINWRAIDSALPSALSKN-----------DHKHQKQLLSKINCE 197
E K E L W + L +N H+ +++ ++ +
Sbjct: 852 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
Query: 198 KEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQIT-NSETLSSIDSL 256
++ E MR + + +L+ ++ Q+ L L + +G + N S+ S+ +
Sbjct: 912 RQ-KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 970
Query: 257 EATEHE 262
+ E E
Sbjct: 971 QKLEEE 976
Score = 40.8 bits (94), Expect = 0.007
Identities = 44/200 (22%), Positives = 92/200 (46%), Gaps = 22/200 (11%)
Query: 50 EKNLEEERQILLQQQKICRNR------ARKYFVESNRRKKAFE-EKRKEQEEKEHQIREQ 102
E+ ++ +IL +QQ+ R R AR+ E+ RR++ E R+++EE+E Q +E+
Sbjct: 780 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
Query: 103 ILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSR 162
L++ +++ E E+ R L ++++ + K EEA ++++E+ L+ E R
Sbjct: 840 ALRRLEERRREEEER--RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR 897
Query: 163 RPTINWRAIDSALP-------------SALSKNDHKHQKQLLSKINCEKEMNENMRATLA 209
+ + + AL + + Q+Q L+++ ++
Sbjct: 898 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 957
Query: 210 TSKNVFQLKLEETQKLLEDQ 229
++ L L E QKL E++
Sbjct: 958 ACQSQATLSLAEIQKLEEER 977
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/246 (21%), Positives = 106/246 (43%), Gaps = 31/246 (12%)
Query: 39 PGSYLDMKIHLEK----NLEEERQILL------QQQKICRNRARKYFVESNRRKKAFEEK 88
PG L+ LEK LE+ER+ ++++ + R+ E RR++ E K
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778
Query: 89 RKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQ 148
R+E+EE + +E+ L R+Q+ +E+ + QR Q+ +A+ R LEE ++ +
Sbjct: 779 RREEEELARRKQEEAL--RRQREQEIALRRQREEEERQQQEEALRR-----LEERRRE-E 830
Query: 149 ESNLKSEVNLPFSRRPTINWRAIDSALPSALSKN-----------DHKHQKQLLSKINCE 197
E K E L W + L +N H+ +++ ++ +
Sbjct: 831 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Query: 198 KEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQIT-NSETLSSIDSL 256
++ E MR + + +L+ ++ Q+ L L + +G + N S+ S+ +
Sbjct: 891 RQ-KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 949
Query: 257 EATEHE 262
+ E E
Sbjct: 950 QKLEEE 955
Score = 40.8 bits (94), Expect = 0.007
Identities = 44/200 (22%), Positives = 92/200 (46%), Gaps = 22/200 (11%)
Query: 50 EKNLEEERQILLQQQKICRNR------ARKYFVESNRRKKAFE-EKRKEQEEKEHQIREQ 102
E+ ++ +IL +QQ+ R R AR+ E+ RR++ E R+++EE+E Q +E+
Sbjct: 759 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 103 ILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSR 162
L++ +++ E E+ R L ++++ + K EEA ++++E+ L+ E R
Sbjct: 819 ALRRLEERRREEEER--RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR 876
Query: 163 RPTINWRAIDSALP-------------SALSKNDHKHQKQLLSKINCEKEMNENMRATLA 209
+ + + AL + + Q+Q L+++ ++
Sbjct: 877 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 936
Query: 210 TSKNVFQLKLEETQKLLEDQ 229
++ L L E QKL E++
Sbjct: 937 ACQSQATLSLAEIQKLEEER 956
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/246 (21%), Positives = 106/246 (43%), Gaps = 31/246 (12%)
Query: 39 PGSYLDMKIHLEK----NLEEERQILL------QQQKICRNRARKYFVESNRRKKAFEEK 88
PG L+ LEK LE+ER+ ++++ + R+ E RR++ E K
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778
Query: 89 RKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQ 148
R+E+EE + +E+ L R+Q+ +E+ + QR Q+ +A+ R LEE ++ +
Sbjct: 779 RREEEELARRKQEEAL--RRQREQEIALRRQREEEERQQQEEALRR-----LEERRRE-E 830
Query: 149 ESNLKSEVNLPFSRRPTINWRAIDSALPSALSKN-----------DHKHQKQLLSKINCE 197
E K E L W + L +N H+ +++ ++ +
Sbjct: 831 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Query: 198 KEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQIT-NSETLSSIDSL 256
++ E MR + + +L+ ++ Q+ L L + +G + N S+ S+ +
Sbjct: 891 RQ-KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 949
Query: 257 EATEHE 262
+ E E
Sbjct: 950 QKLEEE 955
Score = 40.8 bits (94), Expect = 0.007
Identities = 44/200 (22%), Positives = 92/200 (46%), Gaps = 22/200 (11%)
Query: 50 EKNLEEERQILLQQQKICRNR------ARKYFVESNRRKKAFE-EKRKEQEEKEHQIREQ 102
E+ ++ +IL +QQ+ R R AR+ E+ RR++ E R+++EE+E Q +E+
Sbjct: 759 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 103 ILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSR 162
L++ +++ E E+ R L ++++ + K EEA ++++E+ L+ E R
Sbjct: 819 ALRRLEERRREEEER--RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR 876
Query: 163 RPTINWRAIDSALP-------------SALSKNDHKHQKQLLSKINCEKEMNENMRATLA 209
+ + + AL + + Q+Q L+++ ++
Sbjct: 877 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 936
Query: 210 TSKNVFQLKLEETQKLLEDQ 229
++ L L E QKL E++
Sbjct: 937 ACQSQATLSLAEIQKLEEER 956
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/224 (22%), Positives = 97/224 (43%), Gaps = 32/224 (14%)
Query: 57 RQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTE 116
+QIL + K+ +N R E+ K A +KRKE+ + EH ++ + + KQ+ + +E
Sbjct: 357 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLK--VASEEKQERLQRSE 414
Query: 117 KFQRAHVPLSQRRK------AVSRKPVPPLEEAL------------KQIQESNLKSEVNL 158
Q ++K + +K + L+E L K IQE +E+N
Sbjct: 415 NKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINA 474
Query: 159 PFSRRPTINWRAIDSALPS-ALSKNDHKHQK-QLLSKINCEKEMNENMRATLATSKNVFQ 216
F + +N + I + + ND K + +L S++ EK E + A + + +
Sbjct: 475 NFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLA 534
Query: 217 LKLEETQKLLEDQHL----------SNLQKFGDEVNQITNSETL 250
+ E +++E + L S +K G ++Q+T+ L
Sbjct: 535 TAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 578
Score = 39.7 bits (91), Expect = 0.016
Identities = 39/174 (22%), Positives = 80/174 (45%), Gaps = 28/174 (16%)
Query: 182 NDHKHQKQLLSK--INCEKEMNENMRATLATSKNVFQL--KLEETQKLLEDQ-------- 229
ND +K+ +S +N K+ NE + L + +NV + KLE+ +K+LE++
Sbjct: 858 NDLVAEKEAVSSECVNLAKD-NEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHM 916
Query: 230 -----HLSNLQKFGDEVNQ--ITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTIS 282
L LQ++ E+++ + E L I + E+E+ LNK+++ S+++ ++
Sbjct: 917 EKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELT 976
Query: 283 LKPANMQSTNLSC--------FDEDKLAFSKTQHINNWLTNLDASNTQNVTAFS 328
LK + + + +E K AF+ NN ++ + + + S
Sbjct: 977 LKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVIS 1030
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/224 (22%), Positives = 97/224 (43%), Gaps = 32/224 (14%)
Query: 57 RQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTE 116
+QIL + K+ +N R E+ K A +KRKE+ + EH ++ + + KQ+ + +E
Sbjct: 250 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLK--VASEEKQERLQRSE 307
Query: 117 KFQRAHVPLSQRRK------AVSRKPVPPLEEAL------------KQIQESNLKSEVNL 158
Q ++K + +K + L+E L K IQE +E+N
Sbjct: 308 NKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINA 367
Query: 159 PFSRRPTINWRAIDSALPS-ALSKNDHKHQK-QLLSKINCEKEMNENMRATLATSKNVFQ 216
F + +N + I + + ND K + +L S++ EK E + A + + +
Sbjct: 368 NFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLA 427
Query: 217 LKLEETQKLLEDQHL----------SNLQKFGDEVNQITNSETL 250
+ E +++E + L S +K G ++Q+T+ L
Sbjct: 428 TAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 471
Score = 40.0 bits (92), Expect = 0.012
Identities = 48/213 (22%), Positives = 92/213 (43%), Gaps = 31/213 (14%)
Query: 182 NDHKHQKQLLSK--INCEKEMNENMRATLATSKNVFQL--KLEETQKLLEDQ-------- 229
ND +K+ +S +N K+ NE + L + +NV + KLE+ +K+LE++
Sbjct: 751 NDLVAEKEAVSSECVNLAKD-NEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHM 809
Query: 230 -----HLSNLQKFGDEVNQ--ITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTIS 282
L LQ++ E+++ + E L I + E+E+ LNK+++ S+++ ++
Sbjct: 810 EKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELT 869
Query: 283 LKPANMQSTNLSC--------FDEDKLAFSKTQHINNWLTNLDASNTQNVTAFSDILSKS 334
LK + + + +E K AF+ NN ++ + + + S L
Sbjct: 870 LKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFME 929
Query: 335 NVLPSWEYF-NSKEQNPSPLNGTVERATNTANN 366
EYF ++ P P VE + N
Sbjct: 930 K--ERMEYFLSTLPMRPDPELPCVENLNSIELN 960
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/224 (22%), Positives = 97/224 (43%), Gaps = 32/224 (14%)
Query: 57 RQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTE 116
+QIL + K+ +N R E+ K A +KRKE+ + EH ++ + + KQ+ + +E
Sbjct: 357 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLK--VASEEKQERLQRSE 414
Query: 117 KFQRAHVPLSQRRK------AVSRKPVPPLEEAL------------KQIQESNLKSEVNL 158
Q ++K + +K + L+E L K IQE +E+N
Sbjct: 415 NKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINA 474
Query: 159 PFSRRPTINWRAIDSALPS-ALSKNDHKHQK-QLLSKINCEKEMNENMRATLATSKNVFQ 216
F + +N + I + + ND K + +L S++ EK E + A + + +
Sbjct: 475 NFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLA 534
Query: 217 LKLEETQKLLEDQHL----------SNLQKFGDEVNQITNSETL 250
+ E +++E + L S +K G ++Q+T+ L
Sbjct: 535 TAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 578
Score = 39.7 bits (91), Expect = 0.016
Identities = 39/174 (22%), Positives = 80/174 (45%), Gaps = 28/174 (16%)
Query: 182 NDHKHQKQLLSK--INCEKEMNENMRATLATSKNVFQL--KLEETQKLLEDQ-------- 229
ND +K+ +S +N K+ NE + L + +NV + KLE+ +K+LE++
Sbjct: 858 NDLVAEKEAVSSECVNLAKD-NEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHM 916
Query: 230 -----HLSNLQKFGDEVNQ--ITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTIS 282
L LQ++ E+++ + E L I + E+E+ LNK+++ S+++ ++
Sbjct: 917 EKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELT 976
Query: 283 LKPANMQSTNLSC--------FDEDKLAFSKTQHINNWLTNLDASNTQNVTAFS 328
LK + + + +E K AF+ NN ++ + + + S
Sbjct: 977 LKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVIS 1030
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 45.8 bits (107), Expect = 2e-04
Identities = 59/235 (25%), Positives = 107/235 (45%), Gaps = 36/235 (15%)
Query: 50 EKN-LEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRK 108
EKN L E Q+LL++ K +++ ++ +E++ KK+ + K+Q EKE ++RE+I + +
Sbjct: 2642 EKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEY-Q 2700
Query: 109 QKFEEVTEKFQRAHVPLSQRRKA---VSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPT 165
+ E +K Q + +++ + R+ + EE L S+ K E++L S +
Sbjct: 2701 LRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECL-----SSQKLEIDLLKSSKEE 2755
Query: 166 INWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMN---------ENMRATLATSKNVFQ 216
+N N K Q+L ++ K N EN RA +
Sbjct: 2756 LN--------------NSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKS 2801
Query: 217 LKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTLNKE 271
K E +K + + LS LQ + Q T + + +D L TE +E+ TL ++
Sbjct: 2802 CKQLEEEKEILQKELSQLQ--AAQEKQKTGTVMDTKVDEL-TTEIKELKETLEEK 2853
Score = 41.6 bits (96), Expect = 0.004
Identities = 61/291 (20%), Positives = 117/291 (40%), Gaps = 37/291 (12%)
Query: 45 MKIHLEKNLEEERQIL------LQQQKICRNRARKYFVE----SNRRKKAFEEKRKEQEE 94
+K LE NLEE +Q L Q +I N R+ E +N K E+K +E
Sbjct: 445 VKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCH 504
Query: 95 KEHQIR--EQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKP-----------VPPLE 141
E +++ +Q L Q + EE+ K L ++ ++++ V LE
Sbjct: 505 LEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLE 564
Query: 142 EALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALS--KNDHKHQKQLLSKINCEKE 199
+ Q+ K E ++ AL SAL K +++ K+ + +C K
Sbjct: 565 KQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKS 624
Query: 200 MNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVN-----------QITNSE 248
NE + + + K Q K+ + L+ Q + + ++ + V +I N
Sbjct: 625 ENEKLLTQMESEKENLQSKINHLETCLKTQQIKS-HEYNERVRTLEMDRENLSVEIRNLH 683
Query: 249 TLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCFDED 299
+ S+E + Y+ L ++ S Q++ ++ ++++ L+ ED
Sbjct: 684 NVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVED 734
Score = 37.0 bits (84), Expect = 0.10
Identities = 71/349 (20%), Positives = 141/349 (40%), Gaps = 60/349 (17%)
Query: 49 LEKNLEEERQILLQQQKI---CRN---RARKYFVESNRRKKAFEEKRKE-------QEEK 95
L+ LE+ + L++++K+ CR+ R + +++ + A E+K K+ Q +
Sbjct: 318 LQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQN 377
Query: 96 EHQIR---EQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEA--------- 143
R EQ +++++++F+E + QR+ L Q + + L++A
Sbjct: 378 AESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQA 437
Query: 144 -LKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNE 202
L ++ + E NL ++ RA + S + +N+ + + + K N + +
Sbjct: 438 ELDKLTSVKQQLENNLEEFKQKLC--RAEQAFQASQIKENELRRSMEEMKKENNLLKSHS 495
Query: 203 NMRA-----TLATSKNVFQLKLEETQKLLEDQHLSN------LQKFGDEVNQITNSETLS 251
+A A KN+ Q L ++Q E+ N L+ +++NQ NS TL
Sbjct: 496 EQKAREVCHLEAELKNIKQC-LNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLE 554
Query: 252 SI---------------DSLEATEHEEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCF 296
+ D L+ EH LN + S + + + L ++
Sbjct: 555 KLKLAVADLEKQRDCSQDLLKKREHH--IEQLNDKLSKTEKESKALLSALELKKKEYEEL 612
Query: 297 DEDKLAFSKTQHINNWLTNLDASNTQNVTAFSDILS---KSNVLPSWEY 342
E+K FS + N L S +N+ + + L K+ + S EY
Sbjct: 613 KEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEY 661
Score = 35.4 bits (80), Expect = 0.30
Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 32/212 (15%)
Query: 8 TRSAVGELGTESSDNLDRAPLGPRESGGHHRPGSYLDMKIHLEKNLEEERQILLQQ---- 63
T + EL DNL +E+ R + + I K LEEE++IL ++
Sbjct: 2763 TTQILEELKKTKMDNLKYVNQLKKEN---ERAQGKMKLLIKSCKQLEEEKEILQKELSQL 2819
Query: 64 ------QK---ICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRK-QKFEE 113
QK + + + E K+ EEK KE +E + ++ K +K +E
Sbjct: 2820 QAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKE 2879
Query: 114 VTEKFQRAHVPLSQRRKAVSR-----KPVPPLEEALKQIQESNLKSEVNLPFSRRPTI-- 166
+ E Q AH+ SQ+ K SR PV P + + E L S N +R
Sbjct: 2880 MLET-QVAHL-CSQQSKQDSRGSPLLGPVVPGPSPIPSVTEKRLSSGQNKASGKRQRSSG 2937
Query: 167 ---NWRAIDSALPSALSKNDHKHQKQLLSKIN 195
N R A P + SK K +K ++S I+
Sbjct: 2938 IWENGRGPTPATPESFSK---KSKKAVMSGIH 2966
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 45.4 bits (106), Expect = 3e-04
Identities = 55/247 (22%), Positives = 106/247 (42%), Gaps = 24/247 (9%)
Query: 31 RESGGHHRPGSYLDMKIHL---EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEE 87
R+ HHR K H EK E ER+ ++++ ++AR+ + RR+ A E
Sbjct: 93 RKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ---DKARREWERQKRREMAREH 149
Query: 88 KRKEQE---------EKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVP 138
R+E++ E+E ++REQ +QR+QK E+ +RA +R++ +R+ V
Sbjct: 150 SRRERDRLEQLERKRERERKMREQQKEQREQK-----ERERRAE---ERRKEREARREVS 201
Query: 139 PLEEALKQIQESNLK-SEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCE 197
+++ +K S + R P + D P K + + L I+
Sbjct: 202 AHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDS 261
Query: 198 KEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLE 257
+ + ++ A S + + + EE ++ E+ S + +E + ET S+ +
Sbjct: 262 ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEAS 321
Query: 258 ATEHEEI 264
EE+
Sbjct: 322 EQSAEEV 328
Score = 33.1 bits (74), Expect = 1.5
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 12/161 (7%)
Query: 55 EERQILLQQQKICRNRARKYFVESNRRKKAF----EEKRKEQEEKEHQIREQILQQRKQK 110
EER +L Q I + + ES+ + EE+ +E+EE+E E+ ++ +++
Sbjct: 247 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 306
Query: 111 FEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRA 170
EE E + Q + VS + + EE + E++L F R + A
Sbjct: 307 EEEEEETGSNSEEASEQSAEEVSEEEMSEDEE---RENENHLLVVPESRFDRDSGESEEA 363
Query: 171 ---IDSALP--SALSKNDHKHQKQLLSKINCEKEMNENMRA 206
+ P SAL++ D+ LS I ++E+ + + A
Sbjct: 364 EEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPA 404
Score = 31.2 bits (69), Expect = 5.7
Identities = 38/211 (18%), Positives = 87/211 (41%), Gaps = 10/211 (4%)
Query: 69 NRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQR 128
+R K + ++K + R +++E+EH+ R++ +++ + E + +R R
Sbjct: 92 SRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSR 151
Query: 129 RKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQK 188
R+ + + E ++++E + R RA + + H +
Sbjct: 152 RERDRLEQLERKRERERKMREQQKEQREQKERER------RAEERRKEREARREVSAHHR 205
Query: 189 QLLSKINCEKEMNENMRATLATSKNVFQL----KLEETQKLLEDQHLSNLQKFGDEVNQI 244
+ + + + + R+ + F+L K + +K+ E LS+LQ D +
Sbjct: 206 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 265
Query: 245 TNSETLSSIDSLEATEHEEIYLTLNKEHSTS 275
+++E+ S+ + E EE +E STS
Sbjct: 266 SSAESSSAESGSGSEEEEEEEEEEEEEGSTS 296
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 45.4 bits (106), Expect = 3e-04
Identities = 55/247 (22%), Positives = 106/247 (42%), Gaps = 24/247 (9%)
Query: 31 RESGGHHRPGSYLDMKIHL---EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEE 87
R+ HHR K H EK E ER+ ++++ ++AR+ + RR+ A E
Sbjct: 59 RKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ---DKARREWERQKRREMAREH 115
Query: 88 KRKEQE---------EKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVP 138
R+E++ E+E ++REQ +QR+QK E+ +RA +R++ +R+ V
Sbjct: 116 SRRERDRLEQLERKRERERKMREQQKEQREQK-----ERERRAE---ERRKEREARREVS 167
Query: 139 PLEEALKQIQESNLK-SEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCE 197
+++ +K S + R P + D P K + + L I+
Sbjct: 168 AHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDS 227
Query: 198 KEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLE 257
+ + ++ A S + + + EE ++ E+ S + +E + ET S+ +
Sbjct: 228 ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEAS 287
Query: 258 ATEHEEI 264
EE+
Sbjct: 288 EQSAEEV 294
Score = 33.1 bits (74), Expect = 1.5
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 12/161 (7%)
Query: 55 EERQILLQQQKICRNRARKYFVESNRRKKAF----EEKRKEQEEKEHQIREQILQQRKQK 110
EER +L Q I + + ES+ + EE+ +E+EE+E E+ ++ +++
Sbjct: 213 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 272
Query: 111 FEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRA 170
EE E + Q + VS + + EE + E++L F R + A
Sbjct: 273 EEEEEETGSNSEEASEQSAEEVSEEEMSEDEE---RENENHLLVVPESRFDRDSGESEEA 329
Query: 171 ---IDSALP--SALSKNDHKHQKQLLSKINCEKEMNENMRA 206
+ P SAL++ D+ LS I ++E+ + + A
Sbjct: 330 EEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPA 370
Score = 31.2 bits (69), Expect = 5.7
Identities = 38/211 (18%), Positives = 87/211 (41%), Gaps = 10/211 (4%)
Query: 69 NRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQR 128
+R K + ++K + R +++E+EH+ R++ +++ + E + +R R
Sbjct: 58 SRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSR 117
Query: 129 RKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQK 188
R+ + + E ++++E + R RA + + H +
Sbjct: 118 RERDRLEQLERKRERERKMREQQKEQREQKERER------RAEERRKEREARREVSAHHR 171
Query: 189 QLLSKINCEKEMNENMRATLATSKNVFQL----KLEETQKLLEDQHLSNLQKFGDEVNQI 244
+ + + + + R+ + F+L K + +K+ E LS+LQ D +
Sbjct: 172 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 231
Query: 245 TNSETLSSIDSLEATEHEEIYLTLNKEHSTS 275
+++E+ S+ + E EE +E STS
Sbjct: 232 SSAESSSAESGSGSEEEEEEEEEEEEEGSTS 262
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 45.4 bits (106), Expect = 3e-04
Identities = 50/241 (20%), Positives = 104/241 (43%), Gaps = 17/241 (7%)
Query: 51 KNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQK 110
+ + EE Q+ QQ+ N R+Y E + + + +K++E+ E+E++ + ++Q+
Sbjct: 221 RKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFANMQQQR 280
Query: 111 FEEVTEKFQRAHVPLSQRRKAVSRKPVPPL--EEALKQIQESNLKSEVNLPFSRRPTINW 168
E+ K Q Q + A+++K L E L+Q+++ + E + + +
Sbjct: 281 EEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYKSK--LKE 338
Query: 169 RAIDSALPSALSKNDHKHQKQLLSKI-NCEKEMNENMRATLA---TSKNVFQLKLEETQK 224
A K D + Q L + KE EN R T+ + +L + Q+
Sbjct: 339 EAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTMLAKFAEDDRIELMNAQKQR 398
Query: 225 LLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEH---------EEIYLTLNKEHSTS 275
+ + +H ++K +E Q ++ ++ + + EE L L KEH+T+
Sbjct: 399 MKQLEHRRAVEKLIEERRQQFLADKQRELEEWQLQQRRQGFINAIIEEERLKLLKEHATN 458
Query: 276 I 276
+
Sbjct: 459 L 459
Score = 37.4 bits (85), Expect = 0.080
Identities = 47/210 (22%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 42 YLDMKIHLE---KNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQ 98
YLD++ LE K +E + LL+++ + RK + E K+ EK +
Sbjct: 188 YLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEE 247
Query: 99 IREQILQQRKQKFEEVTEKFQR--AHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEV 156
+++ RK+K EE+ E+ ++ + Q+R+ V EE Q+Q + L ++
Sbjct: 248 FQKEQALWRKKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNA-LTQKL 306
Query: 157 NLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQ 216
+R + + K +++ K+ +KEM ++ +A + V Q
Sbjct: 307 EEMLRQREDLEQVRQELYQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQ 366
Query: 217 LKLEETQ--------KLLEDQ--HLSNLQK 236
EE + K ED L N QK
Sbjct: 367 AAKEEEENFRKTMLAKFAEDDRIELMNAQK 396
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 45.1 bits (105), Expect = 4e-04
Identities = 109/552 (19%), Positives = 203/552 (36%), Gaps = 72/552 (13%)
Query: 50 EKNLEEERQILLQQQKICRNRARKY-FVESNRRKKAFEEKRKEQEEKEHQIREQILQQRK 108
EK ++E ++ Q KI + F + + +A E+ +E+ E EH +R +I +QR
Sbjct: 1082 EKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRS 1141
Query: 109 ---QKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPT 165
++ EE++E+ + A S + + +++K ++ + ++E+ L+ E + T
Sbjct: 1142 DLARELEEISERLEEASGATSAQIE-MNKKREAEFQKMRRDLEEATLQHE-----ATAAT 1195
Query: 166 INWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKL 225
+ + DS ++ + KQ L K E +M + A+ + + + +E T +
Sbjct: 1196 LRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRT 1255
Query: 226 LEDQ---------------HLSNLQKF------GDEVNQITNSETLSS------------ 252
+EDQ H N+QK G+ +++ E+L S
Sbjct: 1256 VEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQ 1315
Query: 253 IDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDKLAFSKTQHINNW 312
++ L+ EE H+ R+ L + + + + + W
Sbjct: 1316 LEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQW 1375
Query: 313 LTNLDASNTQNVTAFSDILSK-----SNVLPSWEYFNSK----EQNPSPLNGTVERATNT 363
T + Q + K + E NSK E+ L G VE
Sbjct: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRD 1435
Query: 364 ANNSVPFVSSPPMFVLDKK---CEKTSETSTMRTTDSTS---GAFKRERPLVTESPTFKF 417
S ++ LDKK +K + +S + A K R L TE +
Sbjct: 1436 LERSHTACAT-----LDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRN 1490
Query: 418 SKSQSTSDSLTQEVATFPDQEKYSELNQENGTTSIPTSCVPVATPLV--LPSNIQSARPS 475
+ + T QE+ S+L ++ T LV S++Q A
Sbjct: 1491 AYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEE 1550
Query: 476 AKNSIHIKE-------IDAVQCSDKLDELKDGKEEEIKYFNCNKEELPLFSDSFQDAYIP 528
+ S+ +E ++ Q +LD K+EEI+ N + S DA I
Sbjct: 1551 VEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIR 1610
Query: 529 HNPDSKDEKQKL 540
D+ K+K+
Sbjct: 1611 SRNDALRLKKKM 1622
Score = 33.1 bits (74), Expect = 1.5
Identities = 44/190 (23%), Positives = 89/190 (46%), Gaps = 35/190 (18%)
Query: 51 KNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRK--EQEEKEHQIREQILQQRK 108
KNL+EE L +Q E+ + + E+ +K EQE+ + Q+ L++ +
Sbjct: 1507 KNLQEEISDLTEQ-----------IAETGKNLQEAEKTKKLVEQEKSDLQVA---LEEVE 1552
Query: 109 QKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINW 168
E K R + LSQ + + RK + +E ++Q++ ++ ++
Sbjct: 1553 GSLEHEESKILRVQLELSQVKSELDRKVIEK-DEEIEQLKRNSQRAA------------- 1598
Query: 169 RAIDSALPSAL-SKNDH-KHQKQLLSKIN-CEKEMNENMRATLATSKNV--FQLKLEETQ 223
A+ S L + + S+ND + +K++ +N E ++ + R T K++ Q +L+++Q
Sbjct: 1599 EALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQ 1658
Query: 224 KLLEDQHLSN 233
L+D SN
Sbjct: 1659 LHLDDALRSN 1668
Score = 30.4 bits (67), Expect = 9.8
Identities = 94/525 (17%), Positives = 193/525 (36%), Gaps = 65/525 (12%)
Query: 156 VNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVF 215
+NL F +P + ++ ++ A K D + K+ L++ ++ E +L KN
Sbjct: 834 MNLFFKIKPLL--KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDL 891
Query: 216 QLKLE-ETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTLNKE--- 271
QL+++ ET+ L++ + + + S+ L E TE E +N E
Sbjct: 892 QLQVQSETENLMDAE---------ERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVA 942
Query: 272 HSTSIQRNTISLKP--ANMQSTNLSCFDEDKLAFSKTQHINNWLTNLDASNTQNVTAFSD 329
+++ SLK +++ T E +K ++++ +T L+ N +T
Sbjct: 943 KKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALE-ENISKLTKEKK 1001
Query: 330 ILSKSN--VLPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSSPPMFVLDKKCEKTS 387
L +++ L + K +N +E+ T+ S + D + K
Sbjct: 1002 SLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGS---LEQEKKLRADLERAKRK 1058
Query: 388 ETSTMRTTDSTSGAFKRERPLVTE---SPTFKFSKSQSTSDSLTQEVATFPDQEKYSELN 444
++ + + + ++ + E F+ S+ Q+ D ++V + Q+K EL
Sbjct: 1059 LEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDD--EQVHSLQFQKKIKELQ 1116
Query: 445 QENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSIHIKEIDAVQCSDKLDELKDGKEEE 504
I + L + I+ R + + S++L+E +
Sbjct: 1117 -----ARIEELEEEIEAEHTLRAKIEKQRSDLARELE-------EISERLEEASGATSAQ 1164
Query: 505 IKYFNCNKEELPLFSDSFQDAYIPHNPDSKDEKQKLAET-SSLSNVTSNYDFVGQHKKMK 563
I+ + E ++A + H + ++K A++ + L N V Q + +
Sbjct: 1165 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKE 1224
Query: 564 YNIHERNGVRFLKSILKKESKYEHGYLKALIINQSFKFGNQKAAAIRDSIELTKEKGAEI 623
KS LK E ++AL ++S + + D K K +
Sbjct: 1225 ------------KSELKMEIDDMASNIEAL--SKSKSNIERTCRTVEDQFSEIKAKDEQQ 1270
Query: 624 PKTI-----KKLRWFDETSNIENNAENSHSL-----KNKTGTTQQ 658
+ I +K R + + + E SL K+K TQQ
Sbjct: 1271 TQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQ 1315
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.7 bits (104), Expect = 5e-04
Identities = 49/204 (24%), Positives = 91/204 (44%), Gaps = 24/204 (11%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQE-EKEHQIREQILQQRK 108
+++ EE Q+ ++QK + R RK E ++ EEKR+ QE +++ + EQ+LQ+R+
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 109 Q---KFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESN-LKSEVNLPFSRRP 164
+ + +E KF+ + R + RK + + +Q +E LK E L R
Sbjct: 1350 EQPLRRQERDRKFREEEL----RHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER- 1404
Query: 165 TINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQK 224
+ L + + ++QL + K E + + F LEE Q+
Sbjct: 1405 -------EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF---LEEEQQ 1454
Query: 225 LLEDQHLSNLQKFGDEVNQITNSE 248
L +++H +KF +E + E
Sbjct: 1455 LRQERH----RKFREEEQLLQERE 1474
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/183 (21%), Positives = 85/183 (46%), Gaps = 12/183 (6%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESN--RRKKAFEEKRKEQEEKEHQIREQILQQR 107
E+ E+Q+ +Q++ R ++ E +R ++ ++ R+EQEE+ REQ+L++
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER----REQLLKRE 553
Query: 108 KQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTIN 167
++K E + QR +RR + ++ ++ LK+ QE L+ + +R +
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL-----KREEVE 608
Query: 168 WRAIDSALPSALSKND-HKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLL 226
+ L + + + ++Q L K ++E + + +LK EE ++ L
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668
Query: 227 EDQ 229
E +
Sbjct: 669 EQR 671
Score = 41.6 bits (96), Expect = 0.004
Identities = 28/109 (25%), Positives = 61/109 (55%), Gaps = 6/109 (5%)
Query: 50 EKNLEEE---RQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQ 106
E+ L+EE RQ LQ+++ + RK + RR++ EE+++++ +E Q+R + ++
Sbjct: 257 EEKLQEEEPQRQRELQEEE---EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 107 RKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSE 155
R+++ EE E+ +R +R + + R+ E+ L++ QE + +
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Score = 38.9 bits (89), Expect = 0.028
Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 9/116 (7%)
Query: 44 DMKIHLEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIRE-Q 102
+ K E+ L++E + LL+++ R + R+ E RKK +E ++E+E+ + RE +
Sbjct: 987 EKKYREEEELQQEEEQLLREE---REKRRRQEWERQYRKK--DELQQEEEQLLREEREKR 1041
Query: 103 ILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVP---PLEEALKQIQESNLKSE 155
LQ+R++++ E E Q L + R+ R+ + EE L+Q +E L+ E
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Score = 38.1 bits (87), Expect = 0.047
Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 5/87 (5%)
Query: 49 LEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRK 108
L + +EE Q QQQ++ R + + E RR++ +E+R+EQ+E+ Q E+ QQ +
Sbjct: 286 LRRERQEEEQ---QQQRLRREQQLRRKQEEERREQ--QEERREQQERREQQEERREQQLR 340
Query: 109 QKFEEVTEKFQRAHVPLSQRRKAVSRK 135
++ EE E+ R +R + + R+
Sbjct: 341 REQEERREQQLRREQEEERREQQLRRE 367
Score = 37.7 bits (86), Expect = 0.061
Identities = 24/105 (22%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 46 KIHLEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEE-KEHQIREQIL 104
++ E+ EE++Q L++++ R + + E ++ +E+R++QEE +E Q+R +
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 105 QQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQE 149
++R+Q+ E+ +R L + ++ R+ E+ L++ Q+
Sbjct: 345 ERREQQLRREQEE-ERREQQLRREQEEERREQQLRREQQLRREQQ 388
Score = 37.7 bits (86), Expect = 0.061
Identities = 37/162 (22%), Positives = 74/162 (45%), Gaps = 22/162 (13%)
Query: 49 LEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAF-----EEKRKEQEEKEHQIREQI 103
LE+ L+ E L+Q++ R ++ E RR++ EE+R++Q +E Q R +
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Query: 104 LQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRR 163
+R+++ E + ++ +R H +RR E+ L + ++ + + SR
Sbjct: 658 RLKREEEEERLEQRLKREHE--EERR-----------EQELAEEEQEQARERIK---SRI 701
Query: 164 PTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMR 205
P W+ ++S + SK + +KQ + E+E R
Sbjct: 702 PKWQWQ-LESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Score = 37.7 bits (86), Expect = 0.061
Identities = 40/193 (20%), Positives = 81/193 (41%), Gaps = 15/193 (7%)
Query: 50 EKNLEEERQILLQQ---------QKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIR 100
E+ +EE Q+L ++ ++ CR E ++ E++R+++ E++++
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 101 EQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPL----EEALKQIQESNLKSEV 156
E++ Q+ +Q E EK +R + R + ++ L +E +Q +E + E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 157 NLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQ 216
L +R +R D K +K+ C+ NE R L S+ +
Sbjct: 1204 ELQRQKRKQ-RYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR-QLEDSQLRDR 1261
Query: 217 LKLEETQKLLEDQ 229
++ Q LL +Q
Sbjct: 1262 QSQQDLQHLLGEQ 1274
Score = 37.4 bits (85), Expect = 0.080
Identities = 39/188 (20%), Positives = 87/188 (46%), Gaps = 18/188 (9%)
Query: 54 EEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIR--EQILQQRKQK- 110
E +R+ L++QK+ R + F+E ++ + E +++ ++E++ + R EQ+LQ+R+++
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 111 --FEEVTEKFQRAHVPL-SQRRKAVSR----KPVPPLEEALKQIQESNLKSEVNLPFSRR 163
+E KF L Q R+ R + E+ L++ +E L+ +
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ-------E 1688
Query: 164 PTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQ 223
+R + L + ++Q L + E++ E + T + + + E +
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR-RQERYR 1747
Query: 224 KLLEDQHL 231
K+LE++ L
Sbjct: 1748 KILEEEQL 1755
Score = 36.6 bits (83), Expect = 0.14
Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 21/116 (18%)
Query: 50 EKNLEEERQILLQQQKICRNRA---RKYFVESNRRKKAF-------EEKRKEQEEKEHQI 99
E+ L++E + LL++++ R R R+Y + ++K E++R+++ EK+++
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 100 REQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSE 155
E++ Q+ +Q E EK +R R+K + L+Q +E L+ E
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKK-----------DELQQEEEQLLREE 1037
Score = 35.8 bits (81), Expect = 0.23
Identities = 45/238 (18%), Positives = 100/238 (42%), Gaps = 26/238 (10%)
Query: 44 DMKIHLEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQI 103
+ ++ E+ L E+Q+ +QQ + R+ E +K +E+R+++ ++E + R
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 104 LQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRR 163
L K EE TE+ ++ +R++ + R E +++E + + RR
Sbjct: 458 L-----KREEETERHEQ-----ERRKQQLKRDQEEERRERWLKLEEEERREQQ----ERR 503
Query: 164 PTINWRAIDSALPSALSKNDHKH--QKQLLSKINCEKEMNENMRATLATSKNVFQLKLEE 221
R + L + + + Q++L S+ +E E LK EE
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL---------LKREE 554
Query: 222 TQKLLEDQHLSNLQKFGDE-VNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQR 278
++L +++ L++ +E +Q+ E L+ + E + L +E +++
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Score = 35.8 bits (81), Expect = 0.23
Identities = 37/186 (19%), Positives = 83/186 (44%), Gaps = 9/186 (4%)
Query: 54 EEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQE------EKEHQIREQILQQR 107
E ER+ L ++Q++ + R RK+ E ++ E++ QE E+E Q+R Q ++
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 108 KQKFEEVTEKFQRAHVPLSQR--RKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPT 165
++ E +++ +R + Q+ R+ RK + ++ +Q + + + + F
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
Query: 166 INWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKL 225
+ + L + ++Q + + E++ E+ L + QL+ E +K
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED-EQQLRRQEGQQQLRQERDRKF 1621
Query: 226 LEDQHL 231
ED+ L
Sbjct: 1622 REDEQL 1627
Score = 35.4 bits (80), Expect = 0.30
Identities = 28/119 (23%), Positives = 61/119 (51%), Gaps = 18/119 (15%)
Query: 49 LEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQ-QR 107
L++ L +E+Q+L ++++ + R+ +R++ +E++ +EE+ Q EQ+L+ +R
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREERE------KRRRQEQERQYREEEQLQQEEEQLLREER 948
Query: 108 KQKFEEVTEKFQRAHVPLSQ-----------RRKAVSRKPVPPLEEALKQIQESNLKSE 155
+++ + E+ R L Q +R+ R+ EE L+Q +E L+ E
Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Score = 34.7 bits (78), Expect = 0.52
Identities = 38/195 (19%), Positives = 83/195 (42%), Gaps = 22/195 (11%)
Query: 55 EERQILLQQQKICRNRARKYFVESNR---------RKKAFEEKRK-----------EQEE 94
EER+ +Q + C+ + F + + R+K EEK++ E+EE
Sbjct: 184 EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243
Query: 95 KEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKS 154
KE + RE +L++ ++K +E + QR ++ + + R+ + E ++ Q+ L+
Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL-RRERQEEEQQQQRLRR 302
Query: 155 EVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNV 214
E L + + + + + ++Q L + E+ + +R +
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR-EQEERREQQLRREQEEERRE 361
Query: 215 FQLKLEETQKLLEDQ 229
QL+ E+ ++ E Q
Sbjct: 362 QQLRREQEEERREQQ 376
Score = 34.7 bits (78), Expect = 0.52
Identities = 42/214 (19%), Positives = 88/214 (41%), Gaps = 10/214 (4%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQ 109
++ ++R +++K R R E + ++ ++++E +E+E Q+R+ Q+ ++
Sbjct: 229 QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR 288
Query: 110 KFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWR 169
+ +E ++ QR RRK + +E ++ QE + E RR R
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEER--REQQEERREQQERREQQE-----ERREQQLRR 341
Query: 170 AIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLLEDQ 229
+ L + + +++ + E+E E + QL+ E Q+L +Q
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE--QQLRREQ 399
Query: 230 HLSNLQKFGDEVNQITNSETLSSIDSLEATEHEE 263
L Q+ E Q+ + L L + EE
Sbjct: 400 QLRREQQLRRE-QQLRREQQLRREQQLRREQEEE 432
Score = 34.7 bits (78), Expect = 0.52
Identities = 27/114 (23%), Positives = 60/114 (52%), Gaps = 9/114 (7%)
Query: 49 LEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQE-----EKEHQIREQI 103
LE+ +E ++ +++++ R K + R+ EE+ +++E E+ + R Q
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 104 LQQRKQKFEEVTEKFQR--AHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSE 155
L+++ ++ EEV ++ ++ P +RR+ + R+ EE L+Q +E L+ E
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE--EEELQQEEEQLLREE 1187
Score = 34.7 bits (78), Expect = 0.52
Identities = 46/221 (20%), Positives = 97/221 (43%), Gaps = 28/221 (12%)
Query: 43 LDMKIHLEKNLEEERQILLQQQKICRNRA---RKYFVESNRRKKAF----EEKRKEQEEK 95
L+ + E+ +++E + LL+++ R R R+Y E +++ EE+ K ++E+
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 96 EHQIREQILQQRKQKFEEVTEKFQRAHVPLS---QRRKAVSRKPV---PPLEEALKQIQE 149
E Q RE+ QR+++ + ++ QR+ + ++ AV V E +Q+++
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
Query: 150 SNLK---SEVNLPF---------SRRPTINWRAIDSALP--SALSKNDHKHQKQLLSKIN 195
S L+ S+ +L + W+ D P L + + K K+ K
Sbjct: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
Query: 196 CEKEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQK 236
EK++ R + K E ++LL+++ L++
Sbjct: 1316 EEKQLLREEREEKRRRQET-DRKFREEEQLLQEREEQPLRR 1355
Score = 34.3 bits (77), Expect = 0.68
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 49 LEKNLEEERQILLQQQKICRNRARKYFVESN--RRKKAFEEKRKEQEEKEHQ--IREQIL 104
L++ EE R LL++++ R + K E +R K E +R EQEE+ Q RE+
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 105 QQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSE 155
++R+Q+ + E+ +R L RR+ R+ E ++ E LK E
Sbjct: 627 EERRQQLLKSEEQEERRQQQL--RREQQERREQRLKREEEEERLEQRLKRE 675
Score = 34.3 bits (77), Expect = 0.68
Identities = 53/226 (23%), Positives = 93/226 (41%), Gaps = 33/226 (14%)
Query: 14 ELGTESSDNLDRAPLGPRESGGHHRPGSYLDMKIHLEKNLE--EERQILLQQQKICRNRA 71
+L +E+ + PR+ G R + + E L+ EE + QQQ+
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE---EEQ 763
Query: 72 RKYFV-------ESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKF-EEVTEKFQRAHV 123
R+ F +S R ++ + +E++E Q+R + QQR+Q+F E EK QR
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR--- 820
Query: 124 PLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKND 183
+R++ K + LEE E L+ + + S + D
Sbjct: 821 ---RRQRREREKELQFLEE------EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Query: 184 HKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLLEDQ 229
K + QL +E + R TL +K Q +L + Q+LL+++
Sbjct: 872 QKWRWQL-------EEERKRRRHTL-YAKPALQEQLRKEQQLLQEE 909
Score = 34.3 bits (77), Expect = 0.68
Identities = 27/106 (25%), Positives = 55/106 (51%), Gaps = 10/106 (9%)
Query: 54 EEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQE----EKEHQIREQILQQRKQ 109
+EE Q+L ++ R ++ E R+ + EE ++E+E E+ R Q L+++ +
Sbjct: 1028 QEEEQLLREE------REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 110 KFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSE 155
K EE+ ++ ++ ++R+ R+ EE L+Q +E L+ E
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Score = 33.9 bits (76), Expect = 0.89
Identities = 21/68 (30%), Positives = 40/68 (58%), Gaps = 8/68 (11%)
Query: 54 EEERQILLQQQKICRNRARKY-----FVESNRRKKAFEEKRKEQEEKEHQIREQILQQ-- 106
EE+ Q+ Q+Q++ + R R+Y F + ++ +E +E+E+K Q RE+ L++
Sbjct: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEH 1884
Query: 107 -RKQKFEE 113
R+Q+ EE
Sbjct: 1885 IRRQQKEE 1892
Score = 33.5 bits (75), Expect = 1.2
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 21/116 (18%)
Query: 50 EKNLEEERQILLQQQKICRNRA---RKYFVESNRRKKAFEEKRKEQE-----EKEHQIR- 100
E+ L++E + LL +++ R R R+Y E +++ + R+E E E+E Q R
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
Query: 101 -EQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSE 155
E++ Q+ +Q E EK +R + R EE ++Q +E L+ E
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYRE-----------EEEVQQEEEQLLREE 1157
Score = 33.5 bits (75), Expect = 1.2
Identities = 45/224 (20%), Positives = 95/224 (42%), Gaps = 32/224 (14%)
Query: 50 EKNLEEERQILLQ---QQKICRNRARKYFVESNRRKKAFEEKRKEQEEK----EHQIREQ 102
++ EE Q+L + QQ + R RK+ R++ + +R+E+E K E Q+R Q
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKF------REEEQQLRRQERERKFLQEEQQLRRQ 1719
Query: 103 ILQQRKQKFEEVTEKFQRAHVPLSQR-RKAVSRKPVPPLEEALKQIQESNLKSEVNLPFS 161
L+++ ++ E++ ++ ++ + +R RK + + + P E ++ + E + F
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE-----EQQLRRQERDRKFR 1774
Query: 162 RRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEE 221
+ + L S S + ++QL E L + + + EE
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQL---------RQEREEQQLRPQQRDGKYRWEE 1825
Query: 222 TQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIY 265
Q LE+Q Q+ E ++ +E + E +E++
Sbjct: 1826 EQLQLEEQE----QRLRQERDRQYRAEEQFATQEKSRREEQELW 1865
Score = 33.1 bits (74), Expect = 1.5
Identities = 44/195 (22%), Positives = 82/195 (42%), Gaps = 20/195 (10%)
Query: 54 EEERQILLQQQKICRNRA-RKYFVESNRRKKAFEEKRKEQEE-----KEHQIR----EQI 103
E ER+ L ++Q++ R RK+ E R++ +E+ + QE +E Q+R EQ
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ 1763
Query: 104 L--QQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFS 161
L Q+R +KF E E+ R Q R S + E+ ++ +E L+ P
Sbjct: 1764 LRRQERDRKFRE--EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR-----PQQ 1816
Query: 162 RRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEE 221
R W L + + +Q ++ + ++ R + Q + +E
Sbjct: 1817 RDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ-EKSRREEQELWQEEEQKRRQE 1875
Query: 222 TQKLLEDQHLSNLQK 236
++ L ++H+ QK
Sbjct: 1876 RERKLREEHIRRQQK 1890
Score = 32.7 bits (73), Expect = 2.0
Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
Query: 49 LEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAF---EEKRKEQEEKEHQIREQILQ 105
L + EEER+ +QQ+ R + + + RR++ +E+R+EQ+ + Q E+ Q
Sbjct: 306 LRRKQEEERR---EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 106 QRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQE 149
Q +++ EE + Q +R + + R+ E+ L++ Q+
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Score = 32.3 bits (72), Expect = 2.6
Identities = 21/85 (24%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
Query: 51 KNLEEERQILLQQ--QKICRNRARKYFVES---NRRKKAFEEKRKEQEEKEHQIREQILQ 105
K L+EE+Q+ Q+ Q++ ++R RK+ E +R+++ + + +EQ+ + + + L+
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450
Query: 106 QRKQKFEEVTEKFQRAHVPLSQRRK 130
+ +Q +E KF+ L +R +
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREE 1475
Score = 32.0 bits (71), Expect = 3.4
Identities = 26/113 (23%), Positives = 58/113 (51%), Gaps = 7/113 (6%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNR-RKKAFEEKRKEQEEKEHQIREQILQQRK 108
E+ EE Q L +QQ R RK+ E + R++ ++R++ +++ + EQ+ Q+R+
Sbjct: 1514 ERKFLEEEQQLHRQQ-----RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568
Query: 109 QKFEEVTEKFQRAHVPLSQ-RRKAVSRKPVPPLEEALKQIQESNLKSEVNLPF 160
++ E+ ++ + + RR+ RK + ++ +Q + L+ E + F
Sbjct: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Score = 31.2 bits (69), Expect = 5.7
Identities = 40/221 (18%), Positives = 89/221 (40%), Gaps = 19/221 (8%)
Query: 54 EEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQ---ILQQRKQK 110
E +R+ ++Q++ R + F+E ++ + ++ +EE+ Q RE+ Q+R +K
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Query: 111 FEEVTEKFQRAHVPLSQRRKAV-SRKPVPPLEEALKQI-----QESNLKSEVNLPFSRRP 164
F E ++ +R R + + S++P E +Q+ Q L+ E L R
Sbjct: 1487 FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 165 TINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQK 224
+ D + ++QL + K E + + E+ +K
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVR----------RQEQERK 1596
Query: 225 LLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIY 265
+ED+ Q+ ++ Q + + L+ E ++++
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
Score = 31.2 bits (69), Expect = 5.7
Identities = 31/104 (29%), Positives = 54/104 (51%), Gaps = 9/104 (8%)
Query: 51 KNLEEERQILLQQ--QKICRNRARKYFVESNRRKKAFEEK--RKEQEEK----EHQIREQ 102
K L+EE+Q+ Q+ Q+ ++R RK+ E R++ E++ R+E++ K E ++R Q
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591
Query: 103 ILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQ 146
Q+RK +E + Q L Q R R+ L+E +Q
Sbjct: 1592 -EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Score = 30.4 bits (67), Expect = 9.8
Identities = 44/237 (18%), Positives = 99/237 (41%), Gaps = 14/237 (5%)
Query: 44 DMKIHLEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIR--E 101
+ ++ E+ E+Q+ +Q++ R + + E RR++ + +R++Q +E Q+R +
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ--QLRREQQLRREQQLRREQ 393
Query: 102 QILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFS 161
Q+ ++++ + E+ + Q+ RR+ R+ K QE + E L
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE---RREQRLKRE 450
Query: 162 RRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEE 221
+ +W + +++ + +KQ L K + E+E E + Q + E
Sbjct: 451 QEERRDWLKRE----EETERHEQERRKQQL-KRDQEEERRERWLKLEEEERREQQERRE- 504
Query: 222 TQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQR 278
Q+L +Q Q+ + + + L S L + E L +E +++
Sbjct: 505 -QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Score = 30.4 bits (67), Expect = 9.8
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 51 KNLEEERQILLQ--QQKICRNRARKYFVESNRRKKAFEEKRK--EQEEKEHQIREQIL-- 104
+ EE Q+L + +Q++ R + F+E ++ + E RK EQE + + + L
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 105 ------QQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQE 149
QQR++KF + ++ +R QRR+ RK EE L+Q +E
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERG-QQRRQDRDRKFRE--EEQLRQERE 1568
Score = 30.4 bits (67), Expect = 9.8
Identities = 38/205 (18%), Positives = 81/205 (39%), Gaps = 28/205 (13%)
Query: 44 DMKIHLEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIRE-- 101
D K E+ L +ER+ +QQ + R RK+ EE++ ++E+E + E
Sbjct: 1554 DRKFREEEQLRQERE---EQQLSRQERDRKF---------RLEEQKVRRQEQERKFMEDE 1601
Query: 102 ----------QILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESN 151
Q+ Q+R +KF E + Q R++ RK + + +Q +E
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER-DRKFLEEEPQLRRQEREQQ 1660
Query: 152 LKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATS 211
L+ + + F + + L + ++Q L + E++ ++
Sbjct: 1661 LRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF---LQEEQQLR 1717
Query: 212 KNVFQLKLEETQKLLEDQHLSNLQK 236
+ + K E ++L ++ L++
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRR 1742
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 44.7 bits (104), Expect = 5e-04
Identities = 69/281 (24%), Positives = 114/281 (40%), Gaps = 60/281 (21%)
Query: 51 KNLEEERQILLQQQKICRNRARK--YFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRK 108
K L++E +ILLQ + N A + + VE+ R++K + E + E+ LQ+ +
Sbjct: 1609 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAE 1668
Query: 109 QKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESN--LKSEVNLPFSRRPTI 166
Q+ EE+ EK RK ++ + +++E N L++EV+
Sbjct: 1669 QEMEEMKEKM---------------RKFAKSKQQKILELEEENDRLRAEVH--------- 1704
Query: 167 NWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLL 226
A D+A + + LLS KE E ++ T FQ + E L
Sbjct: 1705 --PAGDTA---------KECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1753
Query: 227 EDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPA 286
E+ D +QI + +S +LEATE + + +E + SI T
Sbjct: 1754 EEVQ--------DLKHQIEGN--VSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSL 1803
Query: 287 NMQSTNLSCFDEDKLA----------FSKTQHINNWLTNLD 317
+M ST +C + A FS INN+L +D
Sbjct: 1804 SM-STRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQID 1843
Score = 39.7 bits (91), Expect = 0.016
Identities = 57/273 (20%), Positives = 105/273 (38%), Gaps = 49/273 (17%)
Query: 54 EEERQILLQQ--QKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKF 111
E+ QIL QQ Q + + VE+ R + ++ E E E ++ LQ+
Sbjct: 286 EQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHL 345
Query: 112 EEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAI 171
E E+ +A L R A+ +K +EE I
Sbjct: 346 LEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSL--------------------- 384
Query: 172 DSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLLEDQHL 231
K ++L S + K+ N + L KN ++ +T + LEDQ
Sbjct: 385 ------------QKTGQELQSACDALKDQN----SKLLQDKNEQAVQSAQTIQQLEDQ-- 426
Query: 232 SNLQKFGDEVNQITNSETLSSIDSLEATEHEEIY----LTLNKEHSTSIQRNTISLKPAN 287
LQ+ E++Q N L ++ T ++Y + +E+ S+Q+ + L+ N
Sbjct: 427 --LQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELE--N 482
Query: 288 MQSTNLSCFDEDKLAFSKTQHINNWLTNLDASN 320
+ L E + ++ + +++ +T L+A N
Sbjct: 483 EKGALLLSSIELEELKAENEKLSSQITLLEAQN 515
Score = 38.5 bits (88), Expect = 0.036
Identities = 107/460 (23%), Positives = 184/460 (40%), Gaps = 89/460 (19%)
Query: 86 EEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKA--VSRKPVPPLEEA 143
E + KE +E+ Q++ ++ + KQK EE+ E+ RA + ++ +A +SRK EA
Sbjct: 1444 EMQAKEHDERIKQLQVELCEM-KQKPEEIGEE-SRAKQQIQRKLQAALISRK------EA 1495
Query: 144 LKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNEN 203
LK+ +L+ E++L R TI L+K+ + Q+ ++ N EK+
Sbjct: 1496 LKE--NKSLQEELSLA---RGTIE----------RLTKSLADVESQVSAQ-NKEKDTVLG 1539
Query: 204 MRATLATSKNVFQLKLEETQKLLEDQHLSN--------LQKFGDEVNQITNS-ETLSSID 254
A L ++ +L E + LLE+Q LS+ L+ ++ ++ E+L S
Sbjct: 1540 RLALLQEERD--KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSK 1597
Query: 255 SLEATEHEEIYLTLNKEHSTSIQR-NTISLKPANMQSTNLSCFDEDKLAFSKTQHINNWL 313
E+TE +E + L KE+ +Q +S + +Q + E + + K +
Sbjct: 1598 IAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS----- 1652
Query: 314 TNLDASNTQNVTAFSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERATNTANNSVPFVSS 373
T + T+ ++ + ++ SK+Q L +R +
Sbjct: 1653 TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVH-------- 1704
Query: 374 PPMFVLDKKCEKTSETSTMRTTDSTSGAFKRERPLVT---ESPTFKFSKSQSTSDSLTQE 430
P K+C M T S++ + K E V E+ + KF S DSL++E
Sbjct: 1705 -PAGDTAKEC--------METLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEE 1755
Query: 431 VATFPDQ--------------EKYSELNQ--ENGTTSIP----------TSCVPVATPLV 464
V Q EK+ E GT SIP S P + V
Sbjct: 1756 VQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESV 1815
Query: 465 LPSNIQSARPSAKNSIHIKEIDAVQCSDKLDELKDGKEEE 504
+ + S S H + + +Q D+L E G EEE
Sbjct: 1816 PSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEE 1855
Score = 37.4 bits (85), Expect = 0.080
Identities = 46/229 (20%), Positives = 98/229 (42%), Gaps = 37/229 (16%)
Query: 53 LEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEH-QIREQILQQRKQKF 111
LEEE+Q L++++ + RK ++E + +KE K H + +++L++++Q+
Sbjct: 1968 LEEEKQQLVKEKTKVESEIRKEYLEK------IQGAQKEPGNKSHAKELQELLKEKQQEV 2021
Query: 112 EEVTEKFQRAHVPLSQRRKAV---------SRKPVPPLEEALKQIQESNLKSEVNLPFSR 162
+++ + R +S + V S+K + +E L Q E K++ L
Sbjct: 2022 KQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAEL---- 2077
Query: 163 RPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEET 222
++ L + + L + +KE+ N + + K + LE
Sbjct: 2078 ----------ASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDE-DLERR 2126
Query: 223 QKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYLTLNKE 271
+ E++HL + ++++ + + LE T EI +TLNK+
Sbjct: 2127 LEQAEEKHLKEKKNMQEKLDALRREKV-----HLEET-IGEIQVTLNKK 2169
Score = 33.9 bits (76), Expect = 0.89
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 12/92 (13%)
Query: 22 NLDRAPLGPRESGGHHRPGSYLDMKIHLEKNLEEERQILLQQQKICRNRARKYFVESNRR 81
N+D AP P+E G HR K E+ E ++ QQ++C R E N
Sbjct: 3106 NIDVAPGAPQEKNGVHR-------KSDPEELREPQQSFSEAQQQLCNTRQ-----EVNEL 3153
Query: 82 KKAFEEKRKEQEEKEHQIREQILQQRKQKFEE 113
+K EE+R ++ E+ + Q R+ + E
Sbjct: 3154 RKLLEEERDQRVAAENALSVAEEQIRRLEHSE 3185
Score = 33.1 bits (74), Expect = 1.5
Identities = 58/285 (20%), Positives = 114/285 (40%), Gaps = 25/285 (8%)
Query: 40 GSYLDMKIHLEKN---LEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKE 96
GS K LE+ LE+E++ L ++ + + ++ +++ E+ K+Q++
Sbjct: 1153 GSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDY 1212
Query: 97 HQIREQILQQRKQKFEEVTEKFQRAHV--------PLSQRRKAVSRKPVPPLEEALKQIQ 148
++++EQ +Q K+ E + ++ ++ + L + S P LEE L +
Sbjct: 1213 NRLQEQFDEQSKEN-ENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKAT 1271
Query: 149 ESNLKSEVNLPFSRRPTINWRAID-SALPSALSKNDHKHQKQLL--SKINCEKEMNENMR 205
E + V L + P + D SAL S K Q + + K+ E +++
Sbjct: 1272 EQHHTQPV-LESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTS 1330
Query: 206 ATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEH---- 261
S+ VFQL+ + ++ LE + L + + + + SS + EH
Sbjct: 1331 ELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLREL 1390
Query: 262 -----EEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDKL 301
E L KE S +S K A + +++ L
Sbjct: 1391 QPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL 1435
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 44.3 bits (103), Expect = 7e-04
Identities = 32/114 (28%), Positives = 60/114 (52%), Gaps = 13/114 (11%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFE--EKRKEQEE----KEHQIR--E 101
EK E+E ++ Q++KI ++ + KK E EK +EQEE +E +IR E
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 102 QILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSE 155
+++Q +++K EV EK Q + ++ + + R+ EE +++ +E + E
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ-----EEKIQEQEEKTWRQE 489
Score = 37.7 bits (86), Expect = 0.061
Identities = 38/182 (20%), Positives = 82/182 (45%), Gaps = 34/182 (18%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQ 109
EK +E +I Q++K+C E + + EEK QEEK H+ E+I +Q +
Sbjct: 297 EKMWRQEEKIQEQEEKMC---------EQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 110 KFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWR 169
+ + EK + + ++ + + R+ EE +++ E + E + WR
Sbjct: 348 MWRQ-EEKIREQEEKIREQEEKMWRQ-----EEKIREQDEKIQEQEEEM---------WR 392
Query: 170 AIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVF--QLKLEETQKLLE 227
+ + + + K Q+++ + EK+M E + ++ + K+ E +++++
Sbjct: 393 QEEK-----IREQEEKRQEKMWRQ---EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 228 DQ 229
DQ
Sbjct: 445 DQ 446
Score = 37.4 bits (85), Expect = 0.080
Identities = 39/189 (20%), Positives = 85/189 (44%), Gaps = 13/189 (6%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKK-----AFEEKRKEQEEKEHQIREQIL 104
EK E+E +I Q++K+ R + + E R++ EEK +EQEEK + E++
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 105 QQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRP 164
+Q ++K E EK Q + ++ + + + E+ +Q ++ + E +
Sbjct: 371 RQ-EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE---KIREQE 426
Query: 165 TINWRAIDSALP-SALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEET- 222
WR + + ++ + +++ K+ E+E + + + Q + E+T
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 223 --QKLLEDQ 229
+KLL+ +
Sbjct: 487 RQEKLLKQE 495
Score = 35.0 bits (79), Expect = 0.40
Identities = 53/209 (25%), Positives = 86/209 (41%), Gaps = 31/209 (14%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQ 109
EK EEE ++ Q++KI R EEK +EQEEK R++ L ++++
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQ----------------EEKIQEQEEKTW--RQEKLLKQEE 496
Query: 110 KFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWR 169
K E EK R + ++ + + + EE +++ +E + EV L
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQ-----EEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 170 AIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKL--LE 227
L L K K +LL +E TL V +LK +E Q L +
Sbjct: 552 VRLQELEERLGKLGQK--AELLG--GAGRESGSQRLPTLTPILQV-ELKSQEAQSLQQQQ 606
Query: 228 DQHLSNLQKFGDEVNQI-TNSETLSSIDS 255
D + +LQ++ Q+ + E L S S
Sbjct: 607 DHYRGHLQQYVAAYQQLASGKEALPSCSS 635
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 44.3 bits (103), Expect = 7e-04
Identities = 32/114 (28%), Positives = 60/114 (52%), Gaps = 13/114 (11%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFE--EKRKEQEE----KEHQIR--E 101
EK E+E ++ Q++KI ++ + KK E EK +EQEE +E +IR E
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 102 QILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSE 155
+++Q +++K EV EK Q + ++ + + R+ EE +++ +E + E
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ-----EEKIQEQEEKTWRQE 489
Score = 37.7 bits (86), Expect = 0.061
Identities = 38/182 (20%), Positives = 82/182 (45%), Gaps = 34/182 (18%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQ 109
EK +E +I Q++K+C E + + EEK QEEK H+ E+I +Q +
Sbjct: 297 EKMWRQEEKIQEQEEKMC---------EQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 110 KFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWR 169
+ + EK + + ++ + + R+ EE +++ E + E + WR
Sbjct: 348 MWRQ-EEKIREQEEKIREQEEKMWRQ-----EEKIREQDEKIQEQEEEM---------WR 392
Query: 170 AIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVF--QLKLEETQKLLE 227
+ + + + K Q+++ + EK+M E + ++ + K+ E +++++
Sbjct: 393 QEEK-----IREQEEKRQEKMWRQ---EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 228 DQ 229
DQ
Sbjct: 445 DQ 446
Score = 37.4 bits (85), Expect = 0.080
Identities = 39/189 (20%), Positives = 85/189 (44%), Gaps = 13/189 (6%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKK-----AFEEKRKEQEEKEHQIREQIL 104
EK E+E +I Q++K+ R + + E R++ EEK +EQEEK + E++
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 105 QQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRP 164
+Q ++K E EK Q + ++ + + + E+ +Q ++ + E +
Sbjct: 371 RQ-EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE---KIREQE 426
Query: 165 TINWRAIDSALP-SALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEET- 222
WR + + ++ + +++ K+ E+E + + + Q + E+T
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 223 --QKLLEDQ 229
+KLL+ +
Sbjct: 487 RQEKLLKQE 495
Score = 35.0 bits (79), Expect = 0.40
Identities = 53/209 (25%), Positives = 86/209 (41%), Gaps = 31/209 (14%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQ 109
EK EEE ++ Q++KI R EEK +EQEEK R++ L ++++
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQ----------------EEKIQEQEEKTW--RQEKLLKQEE 496
Query: 110 KFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWR 169
K E EK R + ++ + + + EE +++ +E + EV L
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQ-----EEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 170 AIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKL--LE 227
L L K K +LL +E TL V +LK +E Q L +
Sbjct: 552 VRLQELEERLGKLGQK--AELLG--GAGRESGSQRLPTLTPILQV-ELKSQEAQSLQQQQ 606
Query: 228 DQHLSNLQKFGDEVNQI-TNSETLSSIDS 255
D + +LQ++ Q+ + E L S S
Sbjct: 607 DHYRGHLQQYVAAYQQLASGKEALPSCSS 635
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 44.3 bits (103), Expect = 7e-04
Identities = 51/214 (23%), Positives = 103/214 (48%), Gaps = 25/214 (11%)
Query: 53 LEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFE 112
L+E + L Q+ + R++A K +E+ +K EEK+ + E++H++ E+I R++K+
Sbjct: 499 LKEMVERLKQECRNFRSQAEKAQLEA---EKTLEEKQIQWLEEKHKLHERI-TDREEKYN 554
Query: 113 EVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQ--------ESNLKSEVNLPFSRRP 164
+ EK QRA + ++RK++ + L+E ++ ++ E+ + + N+PF
Sbjct: 555 QAKEKLQRAAI-AQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEDYT 613
Query: 165 TINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQK 224
+ R D + H + L+ N + N + +S V ++L
Sbjct: 614 RLQKRLKD-------IQRRHNEFRSLILVPNMPPTASIN-PVSFQSSAMVPSMELPFPPH 665
Query: 225 LLEDQH---LSNLQKFGDEVNQITNSETLSSIDS 255
+ E+QH LS L+K +E+ + T + L + S
Sbjct: 666 MQEEQHQRELSLLRKRLEEL-ETTQRKQLEELGS 698
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 44.3 bits (103), Expect = 7e-04
Identities = 51/214 (23%), Positives = 103/214 (48%), Gaps = 25/214 (11%)
Query: 53 LEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFE 112
L+E + L Q+ + R++A K +E+ +K EEK+ + E++H++ E+I R++K+
Sbjct: 499 LKEMVERLKQECRNFRSQAEKAQLEA---EKTLEEKQIQWLEEKHKLHERI-TDREEKYN 554
Query: 113 EVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQ--------ESNLKSEVNLPFSRRP 164
+ EK QRA + ++RK++ + L+E ++ ++ E+ + + N+PF
Sbjct: 555 QAKEKLQRAAI-AQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEDYT 613
Query: 165 TINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQK 224
+ R D + H + L+ N + N + +S V ++L
Sbjct: 614 RLQKRLKD-------IQRRHNEFRSLILVPNMPPTASIN-PVSFQSSAMVPSMELPFPPH 665
Query: 225 LLEDQH---LSNLQKFGDEVNQITNSETLSSIDS 255
+ E+QH LS L+K +E+ + T + L + S
Sbjct: 666 MQEEQHQRELSLLRKRLEEL-ETTQRKQLEELGS 698
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 43.9 bits (102), Expect = 9e-04
Identities = 62/281 (22%), Positives = 123/281 (43%), Gaps = 53/281 (18%)
Query: 45 MKIHLEKNLEEERQILLQ-------QQKICRNRARKYFVESNRRKKAFEEKRKEQEEK-- 95
M+ + + ++ Q++L+ QQ + +++ + ++ N +K E R+E++EK
Sbjct: 681 MQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGT 740
Query: 96 ------EHQIREQILQ-QRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQ 148
E Q++ ++L+ Q K+K ++ EKF + + ++ + LE+ LK
Sbjct: 741 LEQEVQELQLKTELLEKQMKEKENDLQEKFAQL-----EAENSILKDEKKTLEDMLK--I 793
Query: 149 ESNLKSEVNLPFSRRPTINWRAIDSALPSALS--KNDHKHQKQLLSKINCEKEMNENMRA 206
+ + E L F +I ++ DS + +++ KQ ++N E E R
Sbjct: 794 HTPVSQEERLIF--LDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLN---EEIEKQRN 848
Query: 207 TLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEATEHEEIYL 266
T + ++ F++ +E Q + + L K D++ N + L L+A
Sbjct: 849 TFSFAEKNFEVNYQELQ-----EEYACLLKVKDDLEDSKNKQELEYKSKLKA-------- 895
Query: 267 TLNKE-HSTSIQRNTISLKPANMQSTNLSCFDEDKLAFSKT 306
LN+E H I T+ +K S FDEDK ++T
Sbjct: 896 -LNEELHLQRINPTTVKMKS--------SVFDEDKTFVAET 927
Score = 30.8 bits (68), Expect = 7.5
Identities = 55/247 (22%), Positives = 101/247 (40%), Gaps = 36/247 (14%)
Query: 50 EKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQ 109
EKN+ E+ + LL+ QK+ +E N E+K++E+E+K ++L+ +
Sbjct: 2633 EKNVLEKEKKLLELQKL---------LEGN------EKKQREKEKKRSPQDVEVLKTTTE 2677
Query: 110 KFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWR 169
F E + + ++ + +E +++QE L E N+ ++ R
Sbjct: 2678 LFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVR 2737
Query: 170 ---AIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEET---- 222
A S L K D ++ SK C E + S+ LK+ +
Sbjct: 2738 DHLAEAKEKLSILEKEDETEVQE--SKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTP 2795
Query: 223 QKLLEDQHLS-NLQK--FGDEVNQITN--SETLSSIDSLEATE-------HEEIYLTLNK 270
Q L+++ + NLQ +EV +I + +E + + L A E H TL +
Sbjct: 2796 QILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKR 2855
Query: 271 EHSTSIQ 277
EH ++Q
Sbjct: 2856 EHYVAVQ 2862
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,503,563
Number of Sequences: 37866
Number of extensions: 2004269
Number of successful extensions: 13370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 510
Number of HSP's that attempted gapping in prelim test: 8856
Number of HSP's gapped (non-prelim): 2952
length of query: 1117
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1004
effective length of database: 13,968,660
effective search space: 14024534640
effective search space used: 14024534640
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.