Guide to the Human Genome
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Search of human proteins with 224593754

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224593754 AXIN1 up-regulated 1 [Homo sapiens]
         (589 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224593754 AXIN1 up-regulated 1 [Homo sapiens]                     1205   0.0  
gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens]     286   4e-77
gi|13540602 TGF-beta induced apoptosis protein 12 [Homo sapiens]      266   5e-71
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    44   5e-04
gi|18426904 Werner helicase interacting protein isoform 2 [Homo ...    39   0.017
gi|18426902 Werner helicase interacting protein isoform 1 [Homo ...    39   0.017
gi|33239445 eukaryotic translation initiation factor 3, subunit ...    37   0.051
gi|83367072 eukaryotic translation initiation factor 3, subunit ...    37   0.051
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    36   0.11 
gi|203098098 shroom family member 3 protein [Homo sapiens]             36   0.11 
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    35   0.15 
gi|239756829 PREDICTED: zinc finger protein 385C [Homo sapiens]        35   0.15 
gi|239751322 PREDICTED: zinc finger protein 385C [Homo sapiens]        35   0.15 
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    35   0.15 
gi|239745821 PREDICTED: zinc finger protein 385C [Homo sapiens]        35   0.15 
gi|55741677 SET domain containing 1A [Homo sapiens]                    35   0.15 
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...    35   0.15 
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...    35   0.15 
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...    35   0.15 
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...    35   0.15 
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...    35   0.15 
gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]                       35   0.15 
gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]                       35   0.15 
gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]                       35   0.15 
gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]                       35   0.15 
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]     35   0.19 
gi|150417986 ADP-ribosylation factor guanine nucleotide-exchange...    35   0.19 
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        35   0.25 
gi|87298828 complement component 1, q subcomponent, B chain prec...    34   0.33 
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]                34   0.33 

>gi|224593754 AXIN1 up-regulated 1 [Homo sapiens]
          Length = 589

 Score = 1205 bits (3118), Expect = 0.0
 Identities = 589/589 (100%), Positives = 589/589 (100%)

Query: 1   MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD 60
           MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD
Sbjct: 1   MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD 60

Query: 61  FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC 120
           FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC
Sbjct: 61  FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC 120

Query: 121 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV 180
           RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV
Sbjct: 121 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV 180

Query: 181 EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH 240
           EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH
Sbjct: 181 EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH 240

Query: 241 CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL 300
           CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL
Sbjct: 241 CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL 300

Query: 301 QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS 360
           QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS
Sbjct: 301 QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS 360

Query: 361 SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL 420
           SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL
Sbjct: 361 SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL 420

Query: 421 SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPG 480
           SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPG
Sbjct: 421 SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPG 480

Query: 481 TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP 540
           TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP
Sbjct: 481 TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP 540

Query: 541 GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV 589
           GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
Sbjct: 541 GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV 589


>gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens]
          Length = 585

 Score =  286 bits (732), Expect = 4e-77
 Identities = 174/424 (41%), Positives = 238/424 (56%), Gaps = 57/424 (13%)

Query: 1   MTGLLKRKFDQLD---------EDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPW 51
           M+G+LKRKF+++D         E +  VSSS S+    S + S SS              
Sbjct: 1   MSGILKRKFEEVDGSSPCSSVRESDDEVSSSESADSGDSVNPSTSSH------------- 47

Query: 52  DQMPLPDRDFCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTL 111
                          FTP SILKR +R R   V F  +TV+YF R QGFTSVPS+GG TL
Sbjct: 48  ---------------FTPSSILKREKRLRTKNVHFSCVTVYYFTRRQGFTSVPSQGGSTL 92

Query: 112 GMALRHSACRRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPV 171
           GM+ RH++ R+++L EFA+EQ R   E LR+ L+EEKL  L+ K++  G  ++E      
Sbjct: 93  GMSSRHNSVRQYTLGEFAREQERLHREMLREHLREEKLNSLKLKMTKNGTVESEEASTLT 152

Query: 172 VDAIDDASVEEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALR 231
           +D I D  ++ D         ++E  FLQP P ++RRALLRASGV++ID EEK EL+A+R
Sbjct: 153 LDDISDDDIDLD------NTEVDEYFFLQPLPTKKRRALLRASGVKKIDVEEKHELRAIR 206

Query: 232 QSREDCGCHCDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQT 291
            SREDCGC C   CDP+TC+CSLAGIKCQ+D  +FPCGC +EGC N  GR+EFN  RV+T
Sbjct: 207 LSREDCGCDCRVFCDPDTCTCSLAGIKCQVDRMSFPCGCTKEGCSNTAGRIEFNPIRVRT 266

Query: 292 HFIHTLTRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSS- 350
           HF+HT+ +L+LE+  E         Q  P   G  + +     +  P+ + +  +   S 
Sbjct: 267 HFLHTIMKLELEKNRE---------QQIPTLNGCHSEISAHSSSMGPVAHSVEYSIADSF 317

Query: 351 DMTDSSTASSSASGTSEAPDCP---THPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEE 407
           ++     A+     ++E  DC          G  F  GV D S  + L+ S+SD   EEE
Sbjct: 318 EIETEPQAAVLHLQSAEELDCQGEEEEEEEDGSSFCSGVTDSS-TQSLAPSESDEEEEEE 376

Query: 408 EEEE 411
           EEEE
Sbjct: 377 EEEE 380


>gi|13540602 TGF-beta induced apoptosis protein 12 [Homo sapiens]
          Length = 543

 Score =  266 bits (679), Expect = 5e-71
 Identities = 152/324 (46%), Positives = 198/324 (61%), Gaps = 44/324 (13%)

Query: 5   LKRKFDQLDEDNS------SVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPD 58
           LKRKFD +D  +S       +SSS S+  C S +  P+++                    
Sbjct: 9   LKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLN-PPTTA-------------------- 47

Query: 59  RDFCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHS 118
                  SFTP SILKR ++ R   V FD +TV+YF R QGFTSVPS+GG +LGMA RH+
Sbjct: 48  -------SFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHN 100

Query: 119 ACRRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAG-VPQAEA-GLPPVVDAID 176
           + R ++L EFAQEQ     E LR+ LKEEKL   + KL+  G V   EA GL      +D
Sbjct: 101 SVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGL-----TLD 155

Query: 177 DASVEEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSRED 236
           D S E+   + V    +++  FLQP P +RRRALLRASGV RID EEK+EL+A+R SRE+
Sbjct: 156 DVSDED---IDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREE 212

Query: 237 CGCHCDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHT 296
           CGC C   CDPE C+CS AGIKCQ+D  +FPCGC R+GC N  GR+EFN  RV+TH++HT
Sbjct: 213 CGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHT 272

Query: 297 LTRLQLEQEAESFRELEAPAQGSP 320
           + +L+LE + +  R      + SP
Sbjct: 273 IMKLELESKRQVSRPAAPDEEPSP 296


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 54/196 (27%), Positives = 74/196 (37%), Gaps = 32/196 (16%)

Query: 306  AESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELG-----DNSCSSDMTDSSTASS 360
            + SF + E+P    PP P  +   P  PL   P           D++ SS  +  S  ++
Sbjct: 1574 SNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVAT 1633

Query: 361  SASGTSEAPDCPTHPGLPGPGF------QPGVDDDSLARILSFSDSDFGGEEEEEEEGSV 414
               G S AP  P  PG P P        QPG D            +D G EE +    S 
Sbjct: 1634 LTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPP--------PGTDSGIEEVDSRSSSD 1685

Query: 415  GNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSG--VLDEN-ANLDASCFLNGGLE 471
              L+ +S    + +   S  GG ++     +G    SG  +LD   A LD   F  GG  
Sbjct: 1686 HPLETIS--SASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAF--GG-- 1739

Query: 472  GSREGSLPGTSVPPSM 487
                 S PG   PP +
Sbjct: 1740 ----SSTPGPPYPPQL 1751


>gi|18426904 Werner helicase interacting protein isoform 2 [Homo
           sapiens]
          Length = 640

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 20/146 (13%)

Query: 303 EQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPM---------NNELGDNSCSSDMT 353
           E  A S R  E     SPP      L  +  L +P             E GD+   ++  
Sbjct: 49  EPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESR 108

Query: 354 DSSTASSSASGTSEAPDCP----THPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEE 409
           +S  A  + SG    PD P    + PG  G G +P     + A   S S   +   E +E
Sbjct: 109 ESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPA----AAAAAGSASPRSWDEAEAQE 164

Query: 410 EEGSVGNLDNLSCFHPADIFGTSDPG 435
           EE +VG+ D       AD  G  DPG
Sbjct: 165 EEEAVGDGDGDG---DADADGEDDPG 187


>gi|18426902 Werner helicase interacting protein isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 20/146 (13%)

Query: 303 EQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPM---------NNELGDNSCSSDMT 353
           E  A S R  E     SPP      L  +  L +P             E GD+   ++  
Sbjct: 49  EPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESR 108

Query: 354 DSSTASSSASGTSEAPDCP----THPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEE 409
           +S  A  + SG    PD P    + PG  G G +P     + A   S S   +   E +E
Sbjct: 109 ESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPA----AAAAAGSASPRSWDEAEAQE 164

Query: 410 EEGSVGNLDNLSCFHPADIFGTSDPG 435
           EE +VG+ D       AD  G  DPG
Sbjct: 165 EEEAVGDGDGDG---DADADGEDDPG 187


>gi|33239445 eukaryotic translation initiation factor 3, subunit 9
           eta, 116kDa [Homo sapiens]
          Length = 814

 Score = 37.0 bits (84), Expect = 0.051
 Identities = 39/143 (27%), Positives = 52/143 (36%), Gaps = 24/143 (16%)

Query: 307 ESFRELEAPAQGSP---PSPGEEALVPTFPLAKPPMNNELGDNSC--------SSDMTDS 355
           E+  E   P Q  P   P P E  L P  P A      E              S   T+ 
Sbjct: 11  EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70

Query: 356 STASSSASGTSEAPDCPTHPGLPGPGFQPGV------------DDDSLARILSFSDSDFG 403
           +  + +ASG SE+P  P    LPG   +P V            D+ S +R  + S+ D G
Sbjct: 71  AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE-DAG 129

Query: 404 GEEEEEEEGSVGNLDNLSCFHPA 426
           G E    E     L+N     P+
Sbjct: 130 GNEGRAAEAEPRALENGDADEPS 152


>gi|83367072 eukaryotic translation initiation factor 3, subunit 9
           eta, 116kDa [Homo sapiens]
          Length = 814

 Score = 37.0 bits (84), Expect = 0.051
 Identities = 39/143 (27%), Positives = 52/143 (36%), Gaps = 24/143 (16%)

Query: 307 ESFRELEAPAQGSP---PSPGEEALVPTFPLAKPPMNNELGDNSC--------SSDMTDS 355
           E+  E   P Q  P   P P E  L P  P A      E              S   T+ 
Sbjct: 11  EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70

Query: 356 STASSSASGTSEAPDCPTHPGLPGPGFQPGV------------DDDSLARILSFSDSDFG 403
           +  + +ASG SE+P  P    LPG   +P V            D+ S +R  + S+ D G
Sbjct: 71  AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE-DAG 129

Query: 404 GEEEEEEEGSVGNLDNLSCFHPA 426
           G E    E     L+N     P+
Sbjct: 130 GNEGRAAEAEPRALENGDADEPS 152


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 54/243 (22%), Positives = 89/243 (36%), Gaps = 8/243 (3%)

Query: 340  NNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSD 399
            N+   D+S SSD +DSS  SS++S +S + D                D  + +     SD
Sbjct: 932  NSNSSDSSNSSDSSDSSD-SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990

Query: 400  SDFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENAN 459
            S    +  +    S    D+      +D   +SD    +  ++S S  S +S   D + +
Sbjct: 991  SSDSSDSSDSSNSS----DSSDSSDSSDSSNSSDSSNSSDSSNS-SDSSDSSDSSDSSDS 1045

Query: 460  LDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPH 519
             D+S   +         S   +    S D+  SS    S  S DS     +         
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105

Query: 520  YTSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTV 579
              S   SDS D+ ++ +      S   D+S     S    S  ++E+ D    S   D+ 
Sbjct: 1106 SDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163

Query: 580  PAS 582
             +S
Sbjct: 1164 DSS 1166



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 52/247 (21%), Positives = 92/247 (37%), Gaps = 12/247 (4%)

Query: 340 NNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSD 399
           +++  ++S SSD +DS ++ S++S  S++ D  +               DS     S   
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613

Query: 400 SDFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHS----YSGCSFTSGVLD 455
           SD     + + + S    D+      +D   +SD     S  +S     S  S +S   D
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSD---SSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670

Query: 456 ENANLDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYS 515
            + + D+S   +         S   ++   S D+  SS  D S SS  S          +
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730

Query: 516 LGPHYTSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQF 575
                 S   SDS D+ ++ +      S   D+S     S    S  ++++ D    S  
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSN-----SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785

Query: 576 EDTVPAS 582
            D+  +S
Sbjct: 786 NDSSNSS 792



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 52/248 (20%), Positives = 88/248 (35%), Gaps = 9/248 (3%)

Query: 340  NNELGDNSCSSDMTDSSTA-----SSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARI 394
            +++  D+S SSD +DSS +     SS +S +S++ D  +             D  + +  
Sbjct: 782  SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 395  LSFSDSDFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVL 454
               SDS  G + +        N  + S    +D   +SD     S   + S  S  S   
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSS--DSSDSSNSSDSSD--SSDSNESSNSSDSSDS 897

Query: 455  DENANLDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDY 514
              +++ D+S   N         S   +    S D   SS    S  S DS +   +    
Sbjct: 898  SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957

Query: 515  SLGPHYTSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQ 574
            +      S   SDS  +  +        S   D+S     S    S  ++++ D    S 
Sbjct: 958  NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017

Query: 575  FEDTVPAS 582
              D+  +S
Sbjct: 1018 SSDSSNSS 1025



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 40/195 (20%), Positives = 71/195 (36%), Gaps = 8/195 (4%)

Query: 340  NNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSD 399
            +++  D+S SSD +DSS +S S+  ++ +    +             D    +     SD
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089

Query: 400  SDFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENAN 459
            S    +  +  + S    D+      +D   +SD    +S +   S  S +S   D + +
Sbjct: 1090 SSNSSDSSDSSDSS----DSSDSSDSSDSSDSSD----SSNSSDSSDSSDSSDSSDSSNS 1141

Query: 460  LDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPH 519
             D+S             S   +    S D+  SS    S  S DS +   +         
Sbjct: 1142 SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201

Query: 520  YTSQKVSDSLDNIEA 534
              S   SDS D+ ++
Sbjct: 1202 SDSSDSSDSSDSSDS 1216



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 51/243 (20%), Positives = 89/243 (36%), Gaps = 17/243 (6%)

Query: 340 NNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSD 399
           +++  D+S SSD  DSS +S S+  ++ +    +              D S +   S SD
Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS-------------SDSSDSSDSSDSD 819

Query: 400 SDFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENAN 459
           S    +     + S    D+ +    +D   +SD     S   S S  S  S    +++N
Sbjct: 820 SSNSSDSSNSSDSS----DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875

Query: 460 LDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPH 519
              S   +   E S       +S     D+  SS+   S  S +S +  ++         
Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS 935

Query: 520 YTSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTV 579
             S   SDS D+ ++ +      S     SS   +S    S  ++ + D    S   D+ 
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995

Query: 580 PAS 582
            +S
Sbjct: 996 DSS 998



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 47/238 (19%), Positives = 85/238 (35%), Gaps = 8/238 (3%)

Query: 345  DNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGG 404
            D+S SSD ++SS +S+S+  ++ +    ++              DS     S   SD   
Sbjct: 943  DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002

Query: 405  EEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASC 464
              +  +     +  N S    +     S     +S +   S  S +S   D + + D+S 
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062

Query: 465  FLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQK 524
              +         S   +    S D+  SS+   S  S DS +   +           S  
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122

Query: 525  VSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPAS 582
             SDS D+ ++        S   D+S+    S    S  ++++ D    S   D+  +S
Sbjct: 1123 SSDSSDSSDS--------SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 18/51 (35%), Positives = 28/51 (54%)

Query: 340  NNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDS 390
            +++  D+S SS+ +DSS +S S+  TS++ D        G G   G D DS
Sbjct: 1237 SSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 12/77 (15%)

Query: 340  NNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSD 399
            +NE  D+S SSD +DSS  SS +S +S++ D  +             +D+S ++  S + 
Sbjct: 1231 SNESSDSSDSSDSSDSSN-SSDSSDSSDSSDSTSDS-----------NDESDSQSKSGNG 1278

Query: 400  SDFGGEEEEEEEGSVGN 416
            ++ G + + + EGS  N
Sbjct: 1279 NNNGSDSDSDSEGSDSN 1295



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 47/198 (23%), Positives = 73/198 (36%), Gaps = 11/198 (5%)

Query: 341 NELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDS 400
           N   +++ + D    S  +SS+ G +      +     G   +   DDDS     S SD+
Sbjct: 466 NSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD----STSDT 521

Query: 401 DFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANL 460
           +     +    G+ GN DN           +SD     S   S S  S  S   D N++ 
Sbjct: 522 N---NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578

Query: 461 DASCFLNGGLEGSREGSLPGTSVPPSMDAGRSS----SVDLSLSSCDSFELLQALPDYSL 516
           D+    +   + S   S   ++   S D+  SS    S D S S  DS +      D   
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638

Query: 517 GPHYTSQKVSDSLDNIEA 534
               +    SDS DN ++
Sbjct: 639 KSDSSDSNSSDSSDNSDS 656



 Score = 29.6 bits (65), Expect = 8.1
 Identities = 48/229 (20%), Positives = 79/229 (34%), Gaps = 23/229 (10%)

Query: 340 NNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSD 399
           +++  DNS SSD ++SS +S S+  +  +                  D  S +   + SD
Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSS------------------DSSSSSDSSNSSD 688

Query: 400 SDFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENAN 459
           S    +     E S     + S    +D   +SD     S     S  S +S   + + +
Sbjct: 689 SSDSSDSSNSSESS-----DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743

Query: 460 LDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPH 519
            D+S   N         S   +    S D+  SS    S  S DS     +    +    
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDS 803

Query: 520 YTSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALD 568
             S   SDS D+ ++        S   D+S     S    S  +++  D
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852


>gi|203098098 shroom family member 3 protein [Homo sapiens]
          Length = 1996

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 33/127 (25%), Positives = 49/127 (38%), Gaps = 4/127 (3%)

Query: 464  CFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQ 523
            C  +G   G  EG+    S+P      R+     +    DS     + PD++   HY  Q
Sbjct: 1403 CEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAARE--DSLPEESSAPDFANLKHYQKQ 1460

Query: 524  KVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDP--FIDSQFEDTVPA 581
            +   SL +   P  PL   S PG  S    ES++  S P  E  +   F+         +
Sbjct: 1461 QSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSS 1520

Query: 582  SLMEPVP 588
               EP+P
Sbjct: 1521 PTFEPLP 1527


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 316 AQGSPPSPGEEALVPTF---------PLAKPPMNNELGDNSCSSDMTDSSTASSSASGTS 366
           A G PP P  +   P +         P A+ P ++    +S SS  + SS++SSS+S  +
Sbjct: 61  APGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSS-SSSSSSSSSSSSSSSSSSSSSQA 119

Query: 367 EAPDCPTHPGLPGP 380
           + PD P  P    P
Sbjct: 120 KKPDPPLPPAFGAP 133


>gi|239756829 PREDICTED: zinc finger protein 385C [Homo sapiens]
          Length = 1082

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 3/70 (4%)

Query: 316 AQGSPPSPGEEALVPTFPLAKPPMNNE-LGDNSCSSDMTDSSTASSSASGTSEAPDCPTH 374
           A G+P  P  ++ VP  P   PP+      D +C          ++S+S +S  P C   
Sbjct: 794 ASGAPGEP--QSKVPAAPPLGPPLQPPPTPDPTCREPAHSELLDAASSSSSSSCPPCSPE 851

Query: 375 PGLPGPGFQP 384
           PG   PG +P
Sbjct: 852 PGREAPGPEP 861


>gi|239751322 PREDICTED: zinc finger protein 385C [Homo sapiens]
          Length = 1082

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 3/70 (4%)

Query: 316 AQGSPPSPGEEALVPTFPLAKPPMNNE-LGDNSCSSDMTDSSTASSSASGTSEAPDCPTH 374
           A G+P  P  ++ VP  P   PP+      D +C          ++S+S +S  P C   
Sbjct: 794 ASGAPGEP--QSKVPAAPPLGPPLQPPPTPDPTCREPAHSELLDAASSSSSSSCPPCSPE 851

Query: 375 PGLPGPGFQP 384
           PG   PG +P
Sbjct: 852 PGREAPGPEP 861


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 316 AQGSPPSPGEEALVPTF---------PLAKPPMNNELGDNSCSSDMTDSSTASSSASGTS 366
           A G PP P  +   P +         P A+ P ++    +S SS  + SS++SSS+S  +
Sbjct: 61  APGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSS-SSSSSSSSSSSSSSSSSSSSSQA 119

Query: 367 EAPDCPTHPGLPGP 380
           + PD P  P    P
Sbjct: 120 KKPDPPLPPAFGAP 133


>gi|239745821 PREDICTED: zinc finger protein 385C [Homo sapiens]
          Length = 1082

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 3/70 (4%)

Query: 316 AQGSPPSPGEEALVPTFPLAKPPMNNE-LGDNSCSSDMTDSSTASSSASGTSEAPDCPTH 374
           A G+P  P  ++ VP  P   PP+      D +C          ++S+S +S  P C   
Sbjct: 794 ASGAPGEP--QSKVPAAPPLGPPLQPPPTPDPTCREPAHSELLDAASSSSSSSCPPCSPE 851

Query: 375 PGLPGPGFQP 384
           PG   PG +P
Sbjct: 852 PGREAPGPEP 861


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 21/35 (60%), Positives = 23/35 (65%)

Query: 14   EDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEE 48
            E +SS SSSSSSS   S S S SSS S + D EEE
Sbjct: 1034 ESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEE 1068



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 19/36 (52%), Positives = 23/36 (63%)

Query: 13   DEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEE 48
            D ++SS SSSSSSS   S S S SSS   + + EEE
Sbjct: 1032 DSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEE 1067



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 19/39 (48%), Positives = 22/39 (56%)

Query: 10   DQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEE 48
            D   +  SS SSSSSSS   S S S SSS S +   +EE
Sbjct: 1028 DSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEE 1066



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 19/38 (50%), Positives = 22/38 (57%)

Query: 13   DEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGP 50
            +  +SS SSSSSSS   S S S SS  S   + EEE P
Sbjct: 1034 ESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERP 1071



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 20/57 (35%), Positives = 25/57 (43%)

Query: 13   DEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRDFCGPRSFTP 69
            D +N S S S SSS   S S S SSS S +  S  E   +     +R    P +  P
Sbjct: 1024 DGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPP 1080


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 18/116 (15%)

Query: 302 LEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSS 361
           LE E ES  EL AP    PP+   E+ VP  P A+P    EL + + S    D S  S  
Sbjct: 370 LEPEVESSPEL-AP----PPACPSESPVPIAPTAQP---EELLNGAPSPPAVDLSPVSEP 421

Query: 362 ASGTSEAPDCPTHPGLPG--PGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVG 415
                E       P +P   P   P     +    +         EEEEEEEG  G
Sbjct: 422 EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME--------EEEEEEEGEAG 469


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
           isoform 2 [Homo sapiens]
          Length = 1512

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 18/116 (15%)

Query: 302 LEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSS 361
           LE E ES  EL AP    PP+   E+ VP  P A+P    EL + + S    D S  S  
Sbjct: 283 LEPEVESSPEL-AP----PPACPSESPVPIAPTAQP---EELLNGAPSPPAVDLSPVSEP 334

Query: 362 ASGTSEAPDCPTHPGLPG--PGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVG 415
                E       P +P   P   P     +    +         EEEEEEEG  G
Sbjct: 335 EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME--------EEEEEEEGEAG 382


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
           isoform 3 [Homo sapiens]
          Length = 1435

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 18/116 (15%)

Query: 302 LEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSS 361
           LE E ES  EL AP    PP+   E+ VP  P A+P    EL + + S    D S  S  
Sbjct: 206 LEPEVESSPEL-AP----PPACPSESPVPIAPTAQP---EELLNGAPSPPAVDLSPVSEP 257

Query: 362 ASGTSEAPDCPTHPGLPG--PGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVG 415
                E       P +P   P   P     +    +         EEEEEEEG  G
Sbjct: 258 EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME--------EEEEEEEGEAG 305


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 18/116 (15%)

Query: 302 LEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSS 361
           LE E ES  EL AP    PP+   E+ VP  P A+P    EL + + S    D S  S  
Sbjct: 370 LEPEVESSPEL-AP----PPACPSESPVPIAPTAQP---EELLNGAPSPPAVDLSPVSEP 421

Query: 362 ASGTSEAPDCPTHPGLPG--PGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVG 415
                E       P +P   P   P     +    +         EEEEEEEG  G
Sbjct: 422 EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME--------EEEEEEEGEAG 469


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
           isoform 4 [Homo sapiens]
          Length = 1403

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 18/116 (15%)

Query: 302 LEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSS 361
           LE E ES  EL AP    PP+   E+ VP  P A+P    EL + + S    D S  S  
Sbjct: 174 LEPEVESSPEL-AP----PPACPSESPVPIAPTAQP---EELLNGAPSPPAVDLSPVSEP 225

Query: 362 ASGTSEAPDCPTHPGLPG--PGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVG 415
                E       P +P   P   P     +    +         EEEEEEEG  G
Sbjct: 226 EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME--------EEEEEEEGEAG 273


>gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]
          Length = 844

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 23/44 (52%), Positives = 26/44 (59%), Gaps = 1/44 (2%)

Query: 14 EDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLP 57
          E +SS SSSSS SG  SRS S +SS+SR     E  P  Q P P
Sbjct: 31 ERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRP-QQQPQP 73



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 10/108 (9%)

Query: 329 VPTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPDC-------PTHPGLPGPG 381
           +P  PL K   ++    +S SS+ + SS++SSS SG+S            P  P  P P 
Sbjct: 9   LPPPPLEKGRCSSYSDSSSSSSERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRPQ 68

Query: 382 FQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNL---DNLSCFHPA 426
            QP     +  R  + S +   G    +       L    +L+C+ P+
Sbjct: 69  QQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPS 116


>gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]
          Length = 852

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 23/44 (52%), Positives = 26/44 (59%), Gaps = 1/44 (2%)

Query: 14 EDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLP 57
          E +SS SSSSS SG  SRS S +SS+SR     E  P  Q P P
Sbjct: 31 ERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRP-QQQPQP 73



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 10/108 (9%)

Query: 329 VPTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPDC-------PTHPGLPGPG 381
           +P  PL K   ++    +S SS+ + SS++SSS SG+S            P  P  P P 
Sbjct: 9   LPPPPLEKGRCSSYSDSSSSSSERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRPQ 68

Query: 382 FQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNL---DNLSCFHPA 426
            QP     +  R  + S +   G    +       L    +L+C+ P+
Sbjct: 69  QQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPS 116


>gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]
          Length = 858

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 23/44 (52%), Positives = 26/44 (59%), Gaps = 1/44 (2%)

Query: 14 EDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLP 57
          E +SS SSSSS SG  SRS S +SS+SR     E  P  Q P P
Sbjct: 31 ERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRP-QQQPQP 73



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 10/108 (9%)

Query: 329 VPTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPDC-------PTHPGLPGPG 381
           +P  PL K   ++    +S SS+ + SS++SSS SG+S            P  P  P P 
Sbjct: 9   LPPPPLEKGRCSSYSDSSSSSSERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRPQ 68

Query: 382 FQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNL---DNLSCFHPA 426
            QP     +  R  + S +   G    +       L    +L+C+ P+
Sbjct: 69  QQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPS 116


>gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]
          Length = 850

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 23/44 (52%), Positives = 26/44 (59%), Gaps = 1/44 (2%)

Query: 14 EDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLP 57
          E +SS SSSSS SG  SRS S +SS+SR     E  P  Q P P
Sbjct: 31 ERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRP-QQQPQP 73



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 10/108 (9%)

Query: 329 VPTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPDC-------PTHPGLPGPG 381
           +P  PL K   ++    +S SS+ + SS++SSS SG+S            P  P  P P 
Sbjct: 9   LPPPPLEKGRCSSYSDSSSSSSERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRPQ 68

Query: 382 FQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNL---DNLSCFHPA 426
            QP     +  R  + S +   G    +       L    +L+C+ P+
Sbjct: 69  QQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPS 116


>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
          Length = 271

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 4/66 (6%)

Query: 320 PPSPGE----EALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHP 375
           P  PG+     +L       +PP ++    +S SS  + S+TA        E P+ P  P
Sbjct: 20  PQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEP 79

Query: 376 GLPGPG 381
             PGPG
Sbjct: 80  PGPGPG 85


>gi|150417986 ADP-ribosylation factor guanine nucleotide-exchange
           factor 2 [Homo sapiens]
          Length = 1785

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 43/159 (27%), Positives = 61/159 (38%), Gaps = 10/159 (6%)

Query: 294 IHTLTRLQLEQEAESFRELEAPAQGSPPSP--GEEALVPTFPLAKPPMNNELGDNSCSSD 351
           I T    Q+ QEA   RELE P Q  P SP     A+ P F   K             +D
Sbjct: 193 IFTRMENQVLQEA---RELEKPIQSKPQSPVIQAAAVSPKFVRLKHSQAQSKPTTPEKTD 249

Query: 352 MTDSSTA-SSSASGTSEAPDCPTHPGLPGPGFQPGVDD---DSLARILSFSDSDFGGEEE 407
           +T+   A S S   ++E  D P   G    G   G  +   D L  +++ +  +   +  
Sbjct: 250 LTNGEHARSDSGKVSTENGDAPRERGSSLSGTDDGAQEVVKDILEDVVTSAIKEAAEKHG 309

Query: 408 -EEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYS 445
             E E  +G L+   C  P  +   S   G+A    S S
Sbjct: 310 LTEPERVLGELECQECAIPPGVDENSQTNGIADDRQSLS 348


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 28/84 (33%), Positives = 33/84 (39%)

Query: 6    KRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRDFCGPR 65
            KRK       +SS SSSSSSS   S S S SSS S +  S         P        P+
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661

Query: 66   SFTPLSILKRARRERPGRVAFDGI 89
              +P       RR R  R   D +
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSL 2685



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 1/73 (1%)

Query: 313  EAPAQGSPPSPGE-EALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPDC 371
            EA  +G PP P   +    +   +    ++    +S SS  + SS++SSS+S +S +   
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647

Query: 372  PTHPGLPGPGFQP 384
               P  PGP   P
Sbjct: 2648 SPSPAKPGPQALP 2660



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 19/34 (55%), Positives = 22/34 (64%)

Query: 16   NSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEG 49
            +SS SSSSSSS   S S S SSS S +  S+ EG
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565



 Score = 29.6 bits (65), Expect = 8.1
 Identities = 17/43 (39%), Positives = 23/43 (53%)

Query: 14   EDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPL 56
            ++  S SSSSSSS   S S S SSS S +  S  +     +P+
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570


>gi|87298828 complement component 1, q subcomponent, B chain
           precursor [Homo sapiens]
          Length = 253

 Score = 34.3 bits (77), Expect = 0.33
 Identities = 22/65 (33%), Positives = 27/65 (41%)

Query: 352 MTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEE 411
           + D S A  S +G    P  P  PG PGP  QPG       + L     D G   E+ + 
Sbjct: 21  LIDISQAQLSCTGPPAIPGIPGIPGTPGPDGQPGTPGIKGEKGLPGLAGDHGEFGEKGDP 80

Query: 412 GSVGN 416
           G  GN
Sbjct: 81  GIPGN 85


>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
          Length = 895

 Score = 34.3 bits (77), Expect = 0.33
 Identities = 43/158 (27%), Positives = 62/158 (39%), Gaps = 19/158 (12%)

Query: 298 TRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAK-----PPMNNELGDNSCSSDM 352
           TRL+ ++  +   EL   + G P  P    + P + +A      PP    L     +S +
Sbjct: 599 TRLKEKKPGDLSDELRI-SLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPI 657

Query: 353 TDSSTASSSASGTSEAPDCPTHPGLPGP-------GFQPGVDDDSLARI----LSFSDSD 401
            +S +    A G  + P   T   L G         FQ   +++ + R     L  SD +
Sbjct: 658 PESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEE 717

Query: 402 FGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLAS 439
              EEEEEEE      D      PAD  G   PGG +S
Sbjct: 718 -SSEEEEEEESDEDKPDETGFITPAD-SGLITPGGFSS 753


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,463,624
Number of Sequences: 37866
Number of extensions: 1478580
Number of successful extensions: 10601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 9355
Number of HSP's gapped (non-prelim): 1138
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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