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Search of human proteins with 224458301
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224458301 family with sequence similarity 186, member A
[Homo sapiens]
(2351 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224458301 family with sequence similarity 186, member A [Homo... 4600 0.0
gi|14149789 hypothetical protein LOC84070 [Homo sapiens] 159 4e-38
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 100 2e-20
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 95 7e-19
gi|148746195 trichohyalin [Homo sapiens] 94 2e-18
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro... 92 6e-18
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro... 92 6e-18
gi|110665701 leucine rich repeat containing 37A [Homo sapiens] 92 6e-18
gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 92 8e-18
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s... 91 1e-17
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ... 91 1e-17
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 91 2e-17
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 90 3e-17
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens] 89 5e-17
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 88 1e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 88 1e-16
gi|71061468 centromere protein E [Homo sapiens] 88 1e-16
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 85 7e-16
gi|56549696 E1A binding protein p400 [Homo sapiens] 85 1e-15
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 84 1e-15
gi|221219020 NYD-SP11 protein [Homo sapiens] 84 2e-15
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 84 2e-15
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 84 2e-15
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 82 5e-15
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 82 6e-15
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 82 8e-15
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 81 1e-14
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 81 1e-14
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 81 1e-14
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 81 1e-14
>gi|224458301 family with sequence similarity 186, member A [Homo
sapiens]
Length = 2351
Score = 4600 bits (11932), Expect = 0.0
Identities = 2351/2351 (100%), Positives = 2351/2351 (100%)
Query: 1 MFFKMKNEIDNDPESEKCIKDSTIMRREPQNILSPLMLPNLEIPFSVKDIISRIERAQLH 60
MFFKMKNEIDNDPESEKCIKDSTIMRREPQNILSPLMLPNLEIPFSVKDIISRIERAQLH
Sbjct: 1 MFFKMKNEIDNDPESEKCIKDSTIMRREPQNILSPLMLPNLEIPFSVKDIISRIERAQLH 60
Query: 61 RAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYAKTI 120
RAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYAKTI
Sbjct: 61 RAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYAKTI 120
Query: 121 EIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKILSRFS 180
EIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKILSRFS
Sbjct: 121 EIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKILSRFS 180
Query: 181 TSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVSEIQGM 240
TSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVSEIQGM
Sbjct: 181 TSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVSEIQGM 240
Query: 241 LQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETSEAEKE 300
LQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETSEAEKE
Sbjct: 241 LQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETSEAEKE 300
Query: 301 LSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPGPSPQS 360
LSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPGPSPQS
Sbjct: 301 LSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPGPSPQS 360
Query: 361 SRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTPDLTEL 420
SRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTPDLTEL
Sbjct: 361 SRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTPDLTEL 420
Query: 421 RQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLSDNK 480
RQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLSDNK
Sbjct: 421 RQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLSDNK 480
Query: 481 SGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTS 540
SGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTS
Sbjct: 481 SGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTS 540
Query: 541 MMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEP 600
MMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEP
Sbjct: 541 MMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEP 600
Query: 601 QKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESP 660
QKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESP
Sbjct: 601 QKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESP 660
Query: 661 DGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEE 720
DGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEE
Sbjct: 661 DGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEE 720
Query: 721 YFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLS 780
YFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLS
Sbjct: 721 YFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLS 780
Query: 781 YESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLK 840
YESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLK
Sbjct: 781 YESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLK 840
Query: 841 QQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQ 900
QQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQ
Sbjct: 841 QQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQ 900
Query: 901 AEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHR 960
AEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHR
Sbjct: 901 AEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHR 960
Query: 961 RREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDV 1020
RREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDV
Sbjct: 961 RREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDV 1020
Query: 1021 QRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQQA 1080
QRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQQA
Sbjct: 1021 QRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQQA 1080
Query: 1081 QEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQT 1140
QEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQT
Sbjct: 1081 QEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQT 1140
Query: 1141 QVQGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1200
QVQGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA
Sbjct: 1141 QVQGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1200
Query: 1201 QALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQV 1260
QALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQV
Sbjct: 1201 QALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQV 1260
Query: 1261 QELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQA 1320
QELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQA
Sbjct: 1261 QELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQA 1320
Query: 1321 QALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQA 1380
QALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQA
Sbjct: 1321 QALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQA 1380
Query: 1381 QELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQA 1440
QELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQA
Sbjct: 1381 QELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQA 1440
Query: 1441 QALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQA 1500
QALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQA
Sbjct: 1441 QALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQA 1500
Query: 1501 QALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQA 1560
QALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQA
Sbjct: 1501 QALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQA 1560
Query: 1561 QELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQA 1620
QELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQA
Sbjct: 1561 QELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQA 1620
Query: 1621 QALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVTLTSEQTHALESPMNLEQA 1680
QALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVTLTSEQTHALESPMNLEQA
Sbjct: 1621 QALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVTLTSEQTHALESPMNLEQA 1680
Query: 1681 QEQLLKLGVPLTLDKAHTLGSPLTLKQVQWSHRPFQKSKASLPTGQSIISRLSPSLRLSL 1740
QEQLLKLGVPLTLDKAHTLGSPLTLKQVQWSHRPFQKSKASLPTGQSIISRLSPSLRLSL
Sbjct: 1681 QEQLLKLGVPLTLDKAHTLGSPLTLKQVQWSHRPFQKSKASLPTGQSIISRLSPSLRLSL 1740
Query: 1741 ASSAPTAEKSSIFGVSSTPLQISRVPLNQGPFAPGKPLEMGILSEPGKLGAPQTLRSSGQ 1800
ASSAPTAEKSSIFGVSSTPLQISRVPLNQGPFAPGKPLEMGILSEPGKLGAPQTLRSSGQ
Sbjct: 1741 ASSAPTAEKSSIFGVSSTPLQISRVPLNQGPFAPGKPLEMGILSEPGKLGAPQTLRSSGQ 1800
Query: 1801 TLVYGGQSTSAQFPAPQAPPSPGQLPISRAPPTPGQPFIAGVPPTSGQIPSLWAPLSPGQ 1860
TLVYGGQSTSAQFPAPQAPPSPGQLPISRAPPTPGQPFIAGVPPTSGQIPSLWAPLSPGQ
Sbjct: 1801 TLVYGGQSTSAQFPAPQAPPSPGQLPISRAPPTPGQPFIAGVPPTSGQIPSLWAPLSPGQ 1860
Query: 1861 PLVPEASSIPGDLLESGPLTFSEQLQEFQPPATAEQSPYLQAPSTPGQHLATWTLPGRAS 1920
PLVPEASSIPGDLLESGPLTFSEQLQEFQPPATAEQSPYLQAPSTPGQHLATWTLPGRAS
Sbjct: 1861 PLVPEASSIPGDLLESGPLTFSEQLQEFQPPATAEQSPYLQAPSTPGQHLATWTLPGRAS 1920
Query: 1921 SLWIPPTSRHPPTLWPSPAPGKPQKSWSPSVAKKRLAIISSLKSKSVLIHPSAPDFKVAQ 1980
SLWIPPTSRHPPTLWPSPAPGKPQKSWSPSVAKKRLAIISSLKSKSVLIHPSAPDFKVAQ
Sbjct: 1921 SLWIPPTSRHPPTLWPSPAPGKPQKSWSPSVAKKRLAIISSLKSKSVLIHPSAPDFKVAQ 1980
Query: 1981 VPFTTKKFQMSEVSDTSEETQILRDTFAIESFRTFQSHFTKYRTPVYQTPYTDERALLTL 2040
VPFTTKKFQMSEVSDTSEETQILRDTFAIESFRTFQSHFTKYRTPVYQTPYTDERALLTL
Sbjct: 1981 VPFTTKKFQMSEVSDTSEETQILRDTFAIESFRTFQSHFTKYRTPVYQTPYTDERALLTL 2040
Query: 2041 MKPTTSPSSLTTLLRTSQISPLEWYQKSRFPPIDKPWILSSVSDTKKPKVMVPPSSPQEL 2100
MKPTTSPSSLTTLLRTSQISPLEWYQKSRFPPIDKPWILSSVSDTKKPKVMVPPSSPQEL
Sbjct: 2041 MKPTTSPSSLTTLLRTSQISPLEWYQKSRFPPIDKPWILSSVSDTKKPKVMVPPSSPQEL 2100
Query: 2101 EEKRYFVDVEAQKKNLILLNQAIKTCGLPSQLHTMARTLIIEILHMDTVQLGYLFRKYIA 2160
EEKRYFVDVEAQKKNLILLNQAIKTCGLPSQLHTMARTLIIEILHMDTVQLGYLFRKYIA
Sbjct: 2101 EEKRYFVDVEAQKKNLILLNQAIKTCGLPSQLHTMARTLIIEILHMDTVQLGYLFRKYIA 2160
Query: 2161 YRLIQHARNNIMKRLKAIQNTGKGYEARNLHMMLSRLDDYGKKVMQVWTEKQKSLGQKRN 2220
YRLIQHARNNIMKRLKAIQNTGKGYEARNLHMMLSRLDDYGKKVMQVWTEKQKSLGQKRN
Sbjct: 2161 YRLIQHARNNIMKRLKAIQNTGKGYEARNLHMMLSRLDDYGKKVMQVWTEKQKSLGQKRN 2220
Query: 2221 QCLKKMIHVFNQLKKIHELNLSQPIPLIIEEKQIPASTTFVQKPFLKLLMEEDRTSDICK 2280
QCLKKMIHVFNQLKKIHELNLSQPIPLIIEEKQIPASTTFVQKPFLKLLMEEDRTSDICK
Sbjct: 2221 QCLKKMIHVFNQLKKIHELNLSQPIPLIIEEKQIPASTTFVQKPFLKLLMEEDRTSDICK 2280
Query: 2281 KFRQQEDQTEAIWNVDLSTSSYPIAEKTSMHSLWAQLGGYPDIPRLLQLEVQSTFRKSLA 2340
KFRQQEDQTEAIWNVDLSTSSYPIAEKTSMHSLWAQLGGYPDIPRLLQLEVQSTFRKSLA
Sbjct: 2281 KFRQQEDQTEAIWNVDLSTSSYPIAEKTSMHSLWAQLGGYPDIPRLLQLEVQSTFRKSLA 2340
Query: 2341 SLQSRVKKIPK 2351
SLQSRVKKIPK
Sbjct: 2341 SLQSRVKKIPK 2351
>gi|14149789 hypothetical protein LOC84070 [Homo sapiens]
Length = 893
Score = 159 bits (401), Expect = 4e-38
Identities = 124/372 (33%), Positives = 195/372 (52%), Gaps = 42/372 (11%)
Query: 39 PNLEIPFSVKDIISRIERAQLHRAREDIDMQLSEIMNNVHRIMTR------YTLVFNSSS 92
P L P SVK II RIE AQL RA+EDI QLS+I++NV+ ++ R Y L N+ S
Sbjct: 7 PQLVTPTSVKAIILRIEAAQLTRAQEDISTQLSDILDNVNCVINRFQEELGYDLKENAKS 66
Query: 93 ERNVSLTEHKKKQRTNFLEKMATYAKTIEIREKTLANILAWLEEWNDVL--------SEM 144
++ + K K+R LEK+A+++K ++EK L +IL WL +W D L SE
Sbjct: 67 QQR----DPKGKKRFILLEKIASFSKDAMMKEKHLYDILRWLGDWGDTLTYEIGPRKSEE 122
Query: 145 TLMDVDEHHHWIAQME-LLPDTLKAIENNVKILSRFSTSFLDEKKKQKKKILSRGTLWKS 203
+DE WI E +LP +L A + ++ L+ ++ ++ +KK+ + +S+ T W+
Sbjct: 123 EAAALDE---WIEVTEKVLPLSLIATKRGIESLTALCSTLIEGQKKRSQ--VSKRTFWQG 177
Query: 204 WKERVIKR-PSTARALRPDQMISDQLATNTKVSEIQGMLQELIGTTMFSTLENNAIKYIS 262
W+ R + PS + L P+QM+ DQ NTK SE+ MLQEL+ +TMFS E AI+Y++
Sbjct: 178 WQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMA 237
Query: 263 STIVNLSTALSMLNDELKCVNFQSSTVYAHETSEAEKELSLKIIRDLSNENEMLQQKLQD 322
+ + NL+ AL + + E N T Y H +A KE LS++ QQ ++
Sbjct: 238 TVVENLNKALILQHKE----NRSLETKYRHLQMQATKE--------LSSQRLHFQQFMEV 285
Query: 323 AEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNILDKEL 382
E + + L++ ++ Y L L + Q +A G ED + +D
Sbjct: 286 LESRRDALLKQVEILGGRYHDL-----LLMKQALEFQLKKAQNATGQAEDLAEVSVDSPG 340
Query: 383 ENIVDEVQRKET 394
+ + + RKET
Sbjct: 341 PSERETLPRKET 352
Score = 133 bits (334), Expect = 2e-30
Identities = 82/244 (33%), Positives = 134/244 (54%), Gaps = 11/244 (4%)
Query: 2096 SPQELEEKRYFVDVEAQKKNLILLNQAIKTCGLPSQLHTMARTLIIEILHMDTVQLGYLF 2155
SP +++K Y +D+EAQ+KNL LL++ + LP L + A L + + ++L YL
Sbjct: 653 SPANIKKKVYHMDMEAQRKNLQLLSEESEL-RLPHYLRSKALELTTTTMELGALRLQYLC 711
Query: 2156 RKYIAYRLIQHARNNIMKRLKAIQNTGKGYEARNLHMMLSRLDDYGKKVMQVWTEKQKSL 2215
KYI YR +Q R + ++ ++ T Y+A+NL++ L +D +Q WT+KQK L
Sbjct: 712 HKYIFYRRLQSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGL 771
Query: 2216 GQKRNQCLKKMIHVFNQLKKIHELNLSQPIPLIIEEK----QIPASTTFVQKP----FLK 2267
+K +CL M+ +F +L+ E N+ IP + K ++PA++ +P + +
Sbjct: 772 EEKHRECLSSMVTMFPKLQL--EWNVHLNIPEVTSPKPKKCKLPAASPRHIRPSGPTYKQ 829
Query: 2268 LLMEEDRTSDICKKFRQQEDQTEAIWNVDLSTSSYPIAEKTSMHSLWAQLGGYPDIPRLL 2327
+ R + RQQ Q EA+W ++++SSY I +KT QL G+PDIPRLL
Sbjct: 830 PFLSRHRACVPLQMARQQGKQMEAVWKTEVASSSYAIEKKTPASLPRDQLRGHPDIPRLL 889
Query: 2328 QLEV 2331
L+V
Sbjct: 890 TLDV 893
Score = 54.3 bits (129), Expect = 1e-06
Identities = 116/555 (20%), Positives = 221/555 (39%), Gaps = 113/555 (20%)
Query: 586 VEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEK------EELTKQ-VKSHQ 638
+ P M+Q T + ++ + T+ SK E + E L K + H+
Sbjct: 193 LSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHK 252
Query: 639 LVKSLSRVAKETS-ESTRVLESPDGKSEQSNLEEFQEAIM----AFLKQKIDNIGKAFDK 693
+SL + ++T+ L S ++ + ++F E + A LKQ ++ +G +
Sbjct: 253 ENRSLETKYRHLQMQATKELSS-----QRLHFQQFMEVLESRRDALLKQ-VEILGGRYHD 306
Query: 694 KTVPKE--EELLKRAE---AEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748
+ K+ E LK+A+ + + + ++ ET+ + K+T EE E
Sbjct: 307 LLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPR-----KETVMEESQQE- 360
Query: 749 PIKQKKVVSFMPGL--------------HFQKSPISAKSESSTLLSYESTDPVINNLIQM 794
P+K++++ S +P H S ++ +S + + + T+ + L+ +
Sbjct: 361 PMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPL 420
Query: 795 ILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQ-QLLGERNLLKEH 853
+ + + P ++ HK+K+ QE Y Q+G Q+ KQ L R + E
Sbjct: 421 VDRRFPKKWERPVAESL--GHKDKD---QEDYFQKGGLQIKFHCSKQLSLESSRQVTSES 475
Query: 854 YEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQE 913
E E WEE E +E + Q +EEEMW++ QK+ + E +EK +Q E
Sbjct: 476 QE---EPWEE--------EFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLE 524
Query: 914 EEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPER 973
+ L +E Q R +Q E + P R +PE+
Sbjct: 525 D------------------------LAREQ-QRRWVQLEKEQESPRR---------EPEQ 550
Query: 974 GLEDLERQIKTKDQMQMKETQPKELEKMVIQTP-------------MTLSPRWKSVLKDV 1020
ED+ER+I T + ++ + EL ++ P + +SP +
Sbjct: 551 LGEDVERRIFTPTS-RWRDLEKAELS--LVPAPSRTQSAHQSRRPHLPMSPSTQQPALGK 607
Query: 1021 QRSYEGKEFQRNLKT--LENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQ 1078
QR EF +T + P + +T + + P +L IS + K ++
Sbjct: 608 QRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWP-SLQISPANIKKKVYHMDM 666
Query: 1079 QAQEVGITLTPQQAQ 1093
+AQ + L ++++
Sbjct: 667 EAQRKNLQLLSEESE 681
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 100 bits (249), Expect = 2e-20
Identities = 198/883 (22%), Positives = 339/883 (38%), Gaps = 178/883 (20%)
Query: 1073 IHLTPQQAQEVGITLTPQQ----AQAQGITLTLQQAQELGIPLTPQQAQALEI------L 1122
+ +TP + V +T A G + + A + +P+TP + +
Sbjct: 408 VSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPADTPGSPVTSADGPV 467
Query: 1123 FTPQQAQALGIPLTPQQTQVQGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIP 1182
A +P+TP V +T A G A +P+TP A + IP
Sbjct: 468 VPVTSADIPLVPVTPPDGPVVPVT------SADGPVAPVSSADGPVVPVTP--ADSPFIP 519
Query: 1183 LTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQAQALGIT------LTLQQA 1236
+T A +L +P+TP + L S+TP A+ IP+TP + + +T + + A
Sbjct: 520 VTT--ADDLIVPVTPADSPVL--SVTP--AESPAIPVTPADSPIVPVTPANGPVVPVTSA 573
Query: 1237 QQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQA 1296
+P+ P + +T V +P+TP + L +TL A +P+ P +
Sbjct: 574 DSPFVPVIPADGPVVPVTPADSPV----VPVTPADSPVLSVTLADSPA----VPVTPADS 625
Query: 1297 QTLGIPLTPKQAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQA 1356
+P+TP + + A + +P+TP A +++TP ++ A+ P+T QA
Sbjct: 626 PV--VPVTPADGPVVPVA----SADSPFVPVTP--ADDPIVSVTPAESPAI--PVT--QA 673
Query: 1357 QELGIPLTPQHAQALGMPLTTQQAQELGI--------PLTPQQAQALGMPLTTQQAQELG 1408
+P+T + P+TT + + + P+TP A G P+T+
Sbjct: 674 DSPVVPVTSADRPVI--PVTTADGRIVPVTAAGDPIVPVTP--ADTPGSPVTSADGPV-- 727
Query: 1409 IPLTPQQAQELGIPFTPQQAQAQEITLTP------QQAQALGMPLTA--------QQAQE 1454
+P+T A +P TP +T A +P+T+ A
Sbjct: 728 VPVT--SADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADG 785
Query: 1455 LGITLTPQQAQELGIPLTPQQAQALGIPLIPPQ--------AQELGIPLTPQQAQALGIL 1506
+ +TP +P+T A + +P+IP A + +P+TP + + ++
Sbjct: 786 PVVPVTPADTNGPAVPVT--SADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFVPVI 843
Query: 1507 LIPPQAQELGIPLTP--------QQAQALGIP-------LIPPQAQELGIPLTPQQVQAL 1551
A +P+ P L +P L+P A E +PL P
Sbjct: 844 ----SADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPV- 898
Query: 1552 GIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGI-PLTPQQ--------AQELGIP 1602
IP+ PP +L +P+TP P+ P + + + P+TP A +P
Sbjct: 899 -IPVTPPD--DLVVPVTPTDC-----PVAPVTSADCPVVPVTPADSPADPVTAADGPVVP 950
Query: 1603 LTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVT 1662
TP A +P+TP + +S+TP A G + A + VP+TP + + +VT
Sbjct: 951 FTP--ADDPIVPVTPADSPV--VSVTP----ADGPVVPVASADSPFVPVTPADDPIVSVT 1002
Query: 1663 LTSEQTHALESP-MNLEQAQEQLLKLGVPLTLDKAHTLGSPLT-----LKQVQWSHRPFQ 1716
ESP + + QA + VP+T A SP+T + V + P
Sbjct: 1003 -------PAESPAIPVTQADSPV----VPVT--SADRPVSPVTTADGRIVPVTAAGDPIV 1049
Query: 1717 KSKASLPTGQSIISRLSPSLRLSLASSAPTAEKSSIFGVSSTPLQISRVPLNQ--GPFAP 1774
+ G + S P + ++ A S V TP VP+ GP AP
Sbjct: 1050 PVTPADTPGSPVTSADGPVVPVTSADSP---------FVPVTPPDGPVVPVTSADGPVAP 1100
Query: 1775 GKPLEMGILSEPGKLGAPQTLRSSGQTLVYGGQSTSAQFPA-----PQAPPSPGQLPISR 1829
+ ++ G + S+ +V + S P P P +P P+
Sbjct: 1101 VSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLS 1160
Query: 1830 A--------PPTPGQPFIAGVPPTSGQIPSLWAPLSPGQPLVP 1864
P TP + VPP +G + + + SP P++P
Sbjct: 1161 VTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIP 1203
Score = 100 bits (249), Expect = 2e-20
Identities = 186/818 (22%), Positives = 322/818 (39%), Gaps = 163/818 (19%)
Query: 1092 AQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQ 1151
A A + + A + +P+ P + + TP ++ A IP+TP + V +T
Sbjct: 1970 ASADSPLVPVTPADMVVVPVIPADGPVIPV--TPAESPA--IPVTPTDSPVVPVTSA--- 2022
Query: 1152 DQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTP-- 1209
+P I +T A +P+TP + IP+TP +L +P+TP + V+L
Sbjct: 2023 -DSPVIPVT---ADSPFVPVTPADSPV--IPVTPPD--DLVVPVTPIDCPVVPVTLVDCP 2074
Query: 1210 ----QQAQELGIPLTPQQAQALGIT------LTLQQAQQLGIPLTPQQAQALGITLTPKQ 1259
A P+TP + +T + + A L +P+TP + + +T
Sbjct: 2075 VVSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSP 2134
Query: 1260 VQELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQ 1319
V +P+TP + + + A +P+ P A T+ +P+TP IP TP +
Sbjct: 2135 V----VPVTPADSPVISVA----SADSPVVPVTP--ADTVVVPVTPADGPV--IPVTPAE 2182
Query: 1320 AQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQ 1379
+ A IP+TP A + + +TP A + +P+TP + + +P
Sbjct: 2183 SPA--IPVTP--ADSPVVPVTP--------------ADDPVVPVTPADSPIVPVP----P 2220
Query: 1380 AQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQ 1439
A + +P+TP A G P+ + +P+T A +P TP + +T
Sbjct: 2221 ASDPVVPVTP--ADTPGSPVASADGPV--VPVT--SADSPLVPVTPGDSPVVPVT----P 2270
Query: 1440 AQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQ-AQELGIPLTPQ 1498
A + P+T+ +TL A + P+TP P+ P A +P+TP
Sbjct: 2271 ADSPVFPVTSADGPVFPVTL----ADDPVFPVTPADD-----PIFPVSPADSPVVPVTPA 2321
Query: 1499 QAQALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQVQAL------- 1551
+ ++ +PP A +P+T A + +P+IP G+ + L
Sbjct: 2322 N---IPVVPVPP-ANGSVVPVT--SAGSPFVPIIPAD----GLVVLDSSTDVLVVLVSPT 2371
Query: 1552 -GIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQELGI-PLT 1604
GIP +P A + + +T + IP+TP + + + P+ P + + + P+T
Sbjct: 2372 DGIP-VPDLADDPVVSVTTSDSPV--IPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVT 2428
Query: 1605 PQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVTLT 1664
P A + IP+TP A +L + TP A +++TP VP+T + V +VT
Sbjct: 2429 P--ADSPVIPVTP--ADSLVVPATP--ADDPVVSVTPADGPV--VPVTTADIPVISVTSA 2480
Query: 1665 SEQTHALESPMNLEQAQEQLLKLGVPLT-----LDKAHTLGSPLTLKQVQWSHRPFQKSK 1719
+ L + VP T L SP+ L P+
Sbjct: 2481 DSPVVPVTPADGLVVPVTSADSVVVPATPADCPLVPVDPADSPIVL------FTPYDNPV 2534
Query: 1720 ASLPTGQSIISRLSPSLRLSLASSAPTAEKSSIFGVSSTPLQISRVPLNQGPFAPGKPLE 1779
S+ + S + ++P+ SS+ V+ + + V GP P P +
Sbjct: 2535 VSVTSDDSPVFPVTPA-------------DSSVVPVTPAGVPVVPVTPGDGPVVPVTPAD 2581
Query: 1780 MGILSEPGKLGAPQTLRSSGQTLVYGGQSTSAQFPAPQA-----PPSPGQLPISRAPP-- 1832
L P T S+ + + S FP A P +PG P+ P
Sbjct: 2582 --------SLVVPVT--SADSPVFPVTPADSPVFPVSPADDLVVPVTPGDSPVVPVSPAD 2631
Query: 1833 ------TPGQPFIAGVPPTSGQIPSLWAPLSPGQPLVP 1864
TP + V P +G + + + SP P++P
Sbjct: 2632 SPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVPVIP 2669
Score = 84.0 bits (206), Expect = 2e-15
Identities = 149/609 (24%), Positives = 255/609 (41%), Gaps = 108/609 (17%)
Query: 1087 LTPQQAQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGIT 1146
L P A +++T+ A IP+TP + + + A + +P+TP + V I
Sbjct: 1228 LVPDLADDPVVSVTI--ADSPVIPVTPADSPVVPVT----SADSPVVPVTPADSPV--IL 1279
Query: 1147 LTPQQDQAPGISLTTQQ--------AQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQ 1198
+TP P +S+TT A IP+T A + +P+TP +P+T
Sbjct: 1280 VTPV---GPVVSVTTADGPVVLVSTADSPVIPVT--SADSPVVPVTPADGPV--VPVT-- 1330
Query: 1199 QAQALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPK 1258
A + V +TP A + +P+TP + + +T A+ IP+TP + + +T
Sbjct: 1331 SADSPFVPVTP--ADDPIVPVTPADSPIVSVT----PAESPAIPVTPADSPVVPVTSADS 1384
Query: 1259 QVQELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQ 1318
+ IPLT ++ + +T T +P+ P A T G P+T A +P TP
Sbjct: 1385 PL----IPLTTAGSRVVPVTPTGDPI----VPVTP--ADTPGSPVT--SADGPVVPVTPA 1432
Query: 1319 QAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQ 1378
+P+TP +T A +P+TT +P++P + P+T+
Sbjct: 1433 GDPI--VPVTPADTPGSPVT----SADGPVVPVTTPDGPL--VPVSPPDGPVV--PVTSA 1482
Query: 1379 QAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQ 1438
+P+TP A + +P+TT A + +P+TP A +P TP A + +TP
Sbjct: 1483 DGPV--VPVTP--ADSPFIPVTT--ADDPIVPVTP--ADSPVVPVTP--ADIPVVPVTPA 1532
Query: 1439 QAQALGM-----PLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQ-----A 1488
+ + P + G+ L +P++P + P A
Sbjct: 1533 NGPVIHVTSADCPFVPVIPAD-GLVALDSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIA 1591
Query: 1489 QELGIPLTPQQAQALGILLIPPQAQELGIPLTPQQAQALGIPLIP-PQAQELGIPLTPQQ 1547
IP+TP + + + L A +P+T ++ IP++P A P+TP
Sbjct: 1592 DSPVIPVTPADSTVVPVTL----ADGPVVPVT-----SVDIPVVPVTPANGPVAPVTPVD 1642
Query: 1548 VQALGI-----PLIPPQAQELEI-PLTPQQAQALGIPLTPQQAQELGIPLTPQQ------ 1595
+ + ++P + + + P+TP A L +P+TP A +P+TP
Sbjct: 1643 DPVVSVNPADGSVVPVTSADCPVVPVTP--ADGLVVPVTP--ADSPIVPVTPADSPVVLV 1698
Query: 1596 --AQELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITP 1653
A IP+TP A + +P+T + G +T A G + A +L VP+TP
Sbjct: 1699 TSADSPVIPVTP--ADSPVVPVTSADTDSPGSPVT----SADGPVVPVTSADSLPVPVTP 1752
Query: 1654 VNAWVSAVT 1662
+ V VT
Sbjct: 1753 ADGPVVPVT 1761
Score = 77.0 bits (188), Expect = 2e-13
Identities = 209/981 (21%), Positives = 350/981 (35%), Gaps = 190/981 (19%)
Query: 1104 AQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQDQAPGISLTTQQ 1163
A +L +P+TP + L + TP ++ A IP+TP + + + +TP A G +
Sbjct: 523 ADDLIVPVTPADSPVLSV--TPAESPA--IPVTPADSPI--VPVTP----ANGPVVPVTS 572
Query: 1164 AQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQ 1223
A +P+ P +P+TP A +P+TP + L V+L A +P+TP
Sbjct: 573 ADSPFVPVIPADGPV--VPVTP--ADSPVVPVTPADSPVLSVTLADSPA----VPVTPAD 624
Query: 1224 AQALGIT------LTLQQAQQLGIPLTPQQAQALGIT------LTPKQVQELGIPLTPQQ 1271
+ + +T + + A +P+TP + +T + Q +P+T
Sbjct: 625 SPVVPVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSAD 684
Query: 1272 AQALGITLTPKQAQEL---GIPLNP-QQAQTLGIPLTPKQAQALGIPFTPQQAQALGIPL 1327
+ +T + + G P+ P A T G P+T A +P T A + +P+
Sbjct: 685 RPVIPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVT--SADGPVVPVT--SADSPFVPV 740
Query: 1328 TPQQAQTQEITLTP------QQAQALGMPLTT--------QQAQELGIPLTPQHAQALGM 1373
TP +T A +P+T+ A +P+TP +
Sbjct: 741 TPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAV 800
Query: 1374 PLTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGI-----PFTPQQA 1428
P+T+ A +P+ P + + P+T A + +P+TP + + + PF P
Sbjct: 801 PVTS--ADSPFVPVIPADSPVV--PVTP--ADDPIVPVTPADSSFVPVISADSPFVPV-I 853
Query: 1429 QAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQA 1488
A + L +P+ + L P A E +PL P + IP+ PP
Sbjct: 854 PADGPVVVDSSTDVLVVPVFP-----VNCILVPAFADETVVPLNPADSPV--IPVTPPD- 905
Query: 1489 QELGIPLTPQQAQALGIL-------------------------LIP-PQAQELGIPLTPQ 1522
+L +P+TP + ++P A + +P+TP
Sbjct: 906 -DLVVPVTPTDCPVAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPA 964
Query: 1523 QAQALGI-----PLIP-PQAQELGIPLTPQQVQALGI-----PLIP-PQAQELEIPLTPQ 1570
+ + + P++P A +P+TP + + P IP QA +P+T
Sbjct: 965 DSPVVSVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSA 1024
Query: 1571 Q---------------AQALGIPLTP-QQAQELGIPLTPQQAQELGIPLTPQQAQAQGIP 1614
A G P+ P A G P+T A +P+T A + +P
Sbjct: 1025 DRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVT--SADGPVVPVT--SADSPFVP 1080
Query: 1615 LTPQQAQALGIS-----LTPQQA---------QAQGITLTPQQAQALGVPITPVNAWVSA 1660
+TP + ++ + P + A G A VP+TP ++
Sbjct: 1081 VTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIP 1140
Query: 1661 VTLTSEQ----THALESPMNLEQAQEQLLKLGVPLTLDKAHTLGSPLT---LKQVQWSHR 1713
VT + T A +++ A + VP+T + + P + V +
Sbjct: 1141 VTTADDPIVPVTPADSPVLSVTLADSPV----VPVTPADSPVIPVPPANGPVVPVSSADS 1196
Query: 1714 PF-----QKSKASLPTGQSI-ISRLSPSLRLSLASSAP------TAEKSSIFGVSSTPLQ 1761
PF L + + + +SP+ + + A T S + V+
Sbjct: 1197 PFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSP 1256
Query: 1762 ISRVPLNQGPFAPGKPLEMG-ILSEPGKLGAPQTLRSSGQTLVYGGQS-----TSAQFPA 1815
+ V P P P + IL P T LV S TSA P
Sbjct: 1257 VVPVTSADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPV 1316
Query: 1816 PQAPPSPGQL-PISRA-----PPTPGQPFIAGVPPTSGQIPSLWAPLSPGQPLVPEASSI 1869
P+ G + P++ A P TP I V P I S+ SP P+ P S +
Sbjct: 1317 VPVTPADGPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAIPVTPADSPV 1376
Query: 1870 PGDLLESGPLTFSEQLQEFQPPATAEQSPYLQA--PSTPGQHLATWTLPGRASSLWIPPT 1927
PL P T P + TPG + + A +P T
Sbjct: 1377 VPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTS------ADGPVVPVT 1430
Query: 1928 SRHPPTLWPSPA--PGKPQKS 1946
P + +PA PG P S
Sbjct: 1431 PAGDPIVPVTPADTPGSPVTS 1451
Score = 74.7 bits (182), Expect = 1e-12
Identities = 208/967 (21%), Positives = 355/967 (36%), Gaps = 202/967 (20%)
Query: 1109 IPLTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQDQAPGISLTTQQAQKLG 1168
+P+TP + + + TP ++ A IP+TP + V +T +P I LTT ++
Sbjct: 1347 VPVTPADSPIVSV--TPAESPA--IPVTPADSPVVPVTSA----DSPLIPLTTAGSRV-- 1396
Query: 1169 IPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQAQALG 1228
+P+TP +P+TP A G P+T A V +TP A + +P+TP
Sbjct: 1397 VPVTPTGDPI--VPVTP--ADTPGSPVT--SADGPVVPVTP--AGDPIVPVTPADTPGSP 1448
Query: 1229 IT------LTLQQAQQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQALGIT---- 1278
+T + + +P++P + +T V +P+TP + + +T
Sbjct: 1449 VTSADGPVVPVTTPDGPLVPVSPPDGPVVPVTSADGPV----VPVTPADSPFIPVTTADD 1504
Query: 1279 ----LTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGI-----PFTP-----------Q 1318
+TP A +P+ P +P+TP + + PF P
Sbjct: 1505 PIVPVTP--ADSPVVPVTPADIPV--VPVTPANGPVIHVTSADCPFVPVIPADGLVALDS 1560
Query: 1319 QAQALGIPLTPQQ-----------------AQTQEITLTPQQAQALGMPLTTQQAQELG- 1360
L +P++P A + I +TP + + + L +
Sbjct: 1561 STDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTS 1620
Query: 1361 -----IPLTPQHAQ----------------ALGMPLTTQQAQELGIPLTPQQAQALGMPL 1399
+P+TP + A G + A +P+TP A L +P+
Sbjct: 1621 VDIPVVPVTPANGPVAPVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTP--ADGLVVPV 1678
Query: 1400 TTQQAQELGIPLTPQQ--------AQELGIPFTPQQAQAQEITLTPQQAQALGMPLTAQQ 1451
T A +P+TP A IP TP A + + +T + G P+T+
Sbjct: 1679 TP--ADSPIVPVTPADSPVVLVTSADSPVIPVTP--ADSPVVPVTSADTDSPGSPVTSAD 1734
Query: 1452 AQELGITLTPQQAQELGIPLTPQQAQALGI-----PLIP-PQAQELGIPLTPQQAQALGI 1505
+ +T A L +P+TP + + P+ P A +P+TP + + +
Sbjct: 1735 GPVVPVT----SADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPV 1790
Query: 1506 LLIPPQAQELGIPLTPQQAQALGIP-----LIP-PQAQELGIPLTPQQVQALGIPLIPPQ 1559
A + +P+TP + + +P ++P A +P+ P A G+ ++
Sbjct: 1791 TT----ADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVIP----ADGLVVLDSS 1842
Query: 1560 AQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQ 1619
L +P++P GI L P A + + +T A IP+TP A + + +TP
Sbjct: 1843 TDVLVVPVSPTD----GI-LVPDLADDPVVSVTI--ADSPVIPVTP--ADSPVVLVTPAD 1893
Query: 1620 AQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVTLTSEQ----THALESPM 1675
+ ++ + +TP +P+TPV+ V VT + T A +
Sbjct: 1894 GPVVPVTSVDNPV----VPVTPADNPV--IPVTPVDDPVVPVTPADDPIVPVTSADSPIV 1947
Query: 1676 NLEQAQEQLLKLGVPLTLDKAHTLGSPLTLKQVQWSHRPFQKSKASLPTGQSIISRLSPS 1735
++ A + P+T SP+ V + P + +I P
Sbjct: 1948 SVTPADSPVF----PVT-----PADSPVI--PVASADSPLVPVTPADMVVVPVIPADGPV 1996
Query: 1736 LRLSLASSAP---TAEKSSIFGVSSTPLQISRVPLNQGPFAPGKPLEMGIL--SEPGKLG 1790
+ ++ A S T S + V+S + V + PF P P + ++ + P L
Sbjct: 1997 IPVTPAESPAIPVTPTDSPVVPVTSADSPVIPVTADS-PFVPVTPADSPVIPVTPPDDLV 2055
Query: 1791 APQTLRSSGQ---TLVYGG--QSTSAQFPAPQAPPSPGQL-PISRA-----PPTPGQPFI 1839
P T TLV T A P P+ G + P++ A P TP I
Sbjct: 2056 VPVTPIDCPVVPVTLVDCPVVSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLI 2115
Query: 1840 AGVPPTSGQIPSLWAPLSPGQPLVPEASSI--------------PGDLL------ESGPL 1879
V P I S+ SP P+ P S + P D + GP+
Sbjct: 2116 VPVTPADSLIVSVTPADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTPADGPV 2175
Query: 1880 TFSEQLQEFQPPATAEQSPYLQAPSTPGQHLATWTLPGRASSLWIPPTSRHPPTLWPSPA 1939
+ P T SP + P TP P + + +PP S + P+
Sbjct: 2176 IPVTPAESPAIPVTPADSPVV--PVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADT 2233
Query: 1940 PGKPQKS 1946
PG P S
Sbjct: 2234 PGSPVAS 2240
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 95.1 bits (235), Expect = 7e-19
Identities = 117/623 (18%), Positives = 279/623 (44%), Gaps = 74/623 (11%)
Query: 412 ERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYET 471
ER EL + + +E++ + + + L+ + + + + KR ++A ++
Sbjct: 167 ERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQ 226
Query: 472 SGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETK 531
N + ++ E + Q K +++E K + +++ E K + +
Sbjct: 227 VQTNTLQEEMWRQEEELRE------QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
Query: 532 SQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSM 591
+ + EQ ++++ + ++ + + E E +K + E + + +
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
Query: 592 IQFDDTAEPQKGKIKGKKHHI--SSGTITSKEEKTEEKEELTKQ---VKSHQLVKSLSRV 646
+ + Q+ K++ ++ + + KEE+ E+E++ +Q ++ + ++ +
Sbjct: 341 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 647 AKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRA 706
+E E+ R E K E++ E+ + K + ++ +P+++E K
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEE---------------KEWQQQRLPEQKE--KLW 443
Query: 707 EAEKLGIIKAKMEEYFQKVAETVT------KILRKYKDTKKEEQVGEKPIK----QKKVV 756
E EK+ + K+ E +K+ + K+ R+ K ++E+Q+ E+ K ++K+
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 757 SFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHK 816
+ Q + K E + +M E + + T +K
Sbjct: 504 DQEERMWEQDERLREKEER------------MREQKKMWQQEEKMREEKKTQEQEKKTWD 551
Query: 817 EKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQE 876
++EK R+E+ ++E +++M ++ + + ++E EK+ E +E+K W Q E K +
Sbjct: 552 QEEKMREEERMREREKKMR--EEEEMMREQEEKMQEQEEKMRE--QEEKMWEQ--EEKMQ 605
Query: 877 QQSQKQW-QEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQ 935
+Q +K W QEE+MW++E++ +Q E +Q+++ QE+EE +++ E +KM+ Q
Sbjct: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
Query: 936 GLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLED-----------LERQIKT 984
EK GQ +++++ + + + EK +E+++ RG E+ E ++
Sbjct: 666 E---EKMQGQEEKMREQEEKM--QGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWG 720
Query: 985 KDQMQMKETQPK-ELEKMVIQTP 1006
+++M+ KE + + + EKM + P
Sbjct: 721 QEEMREKEERIRDQKEKMQERLP 743
Score = 69.3 bits (168), Expect = 4e-11
Identities = 129/643 (20%), Positives = 263/643 (40%), Gaps = 71/643 (11%)
Query: 290 YAHETSEAEKELSLKIIR------DLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAK 343
Y E ++ LSL++ R +L +N LQ+KL+ AE + ++ ++ +++L K
Sbjct: 160 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEI---QLNVKELKRK 216
Query: 344 LSTSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNILDKEL---ENIVDEVQRKETKDSGIK 400
L + L P Q+ N L +E+ E + E ++K K
Sbjct: 217 LERAKFLL----PQVQT---------------NTLQEEMWRQEEELREQEKKIRKQEEKM 257
Query: 401 WDSTISYTAQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKR 460
W Q ER LR+Q + E + L++ + ++ E + K+
Sbjct: 258 W-------RQEER------LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Query: 461 SHKKATYVYETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEA 520
++ + E +K+ E + + + + L ++ K+M+ E + K +
Sbjct: 305 LREQEEQMQEQEEKMWEQE---EKMREQEEKMWRQEERLWEQEKQMR---EQEQKMRDQE 358
Query: 521 KRKHLSLTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKG 580
+R + + + M EQ K++ E +R + E E +K K
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 581 EIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLV 640
E + Q E ++ + +K I +EEK ++EE+ Q K
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK---- 474
Query: 641 KSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKI-DNIGKAFDKKTVPKE 699
+ R K + ++ E + +Q QE M +++ + + ++K + ++
Sbjct: 475 --MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532
Query: 700 EELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFM 759
EE K E +K + K + +K+ E R+ K ++EE + E+ K ++ M
Sbjct: 533 EE--KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 760 PGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKE 819
+ K + +E + + Q +++ + ++ + +E++
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWE---QEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 820 KQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQS 879
QE+ ++E +E+M K Q G+ ++E EK+ + EEK ++ +E K Q
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQ--GQEEKMREQEEKM-QGQEEK---MREQEEKMRGQE 701
Query: 880 QKQW-QEEEMWKEEQKQ-ATPKQAEQEEKQK-QRGQEEEELPK 919
+K W QEE+MW +E+K + E+EE+ + Q+ + +E LP+
Sbjct: 702 EKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
Score = 65.9 bits (159), Expect = 5e-10
Identities = 109/511 (21%), Positives = 222/511 (43%), Gaps = 91/511 (17%)
Query: 608 KKHHISSGTI--TSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLE------- 658
KK I++GT T+ E E+ K SHQ ++L R + + R+L
Sbjct: 48 KKKKINNGTNPETTTSEGCHSPEDEKKA--SHQHQEALRREIEAQDHTIRILTCQKTELE 105
Query: 659 -----SPDG--KSEQSNLEEFQEAI--------MAFLKQKIDNIGKAFDKKTVPKEEELL 703
S D K E NL E ++ A Q+ + + KK EEL
Sbjct: 106 TALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELT 165
Query: 704 KRAEAEKLGIIKAKM--EEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQK--KVVSFM 759
K +A L + + + EE +K AE K LR + K E Q+ K +K+K + +
Sbjct: 166 KERDALSLELYRNTITNEELKKKNAELQEK-LRLAESEKSEIQLNVKELKRKLERAKFLL 224
Query: 760 PG----------------LHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESER 803
P L Q+ I + E + + + +M E + R
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM----WRQEERLREQEGKMREQEEKMRR 280
Query: 804 DIPTVSTVQKDHKEKEKQ-RQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISEN-- 860
+ +K+ +E+EK+ R+++ L+E +EQM ++++ + ++E EK+
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQ--EEKMWEQEEKMREQEEKMWRQEE 338
Query: 861 --WEEKKAWLQMKEGKQEQQSQKQWQEEE--------------MWKEEQKQATPKQAEQE 904
WE++K ++ +E K Q ++ W+++E MW++E+K ++ +
Sbjct: 339 RLWEQEKQ-MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 905 EKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREK 964
EK+ +EEEE + +++++ + M Q E++ Q +++ ++ + L + ++
Sbjct: 398 EKKM---REEEETMREQEEKMQKQEENMWEQ----EEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 965 GKEK----QKPERGLEDL---ERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVL 1017
+EK ++ R E++ E+++ +++M+ +E Q E E+ + + + + +
Sbjct: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
Query: 1018 KDVQRSYEGKEFQRNLKTL----ENLPDEKE 1044
+ +R E +E R K + E + +EK+
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKK 541
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 93.6 bits (231), Expect = 2e-18
Identities = 152/706 (21%), Positives = 308/706 (43%), Gaps = 75/706 (10%)
Query: 309 LSNENEMLQQKLQ-DAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPGPSPQSSRAIIKV 367
L E E QQ+L+ + EE+ EQ ++ + V E+L + LK P + + ++K
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEV-ERLEQEERREQRLK-REEPEEERRQQLLKS 636
Query: 368 GDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTPDLTELRQQPVAS 427
+ E+ L +E ++E ++ +K + Q + E R+Q +A
Sbjct: 637 EEQEERRQQQLRRE---------QQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 428 EDISEDSTKDNVSLKKGDFYQEDETDEYQS--WKRSHKKATYVYETSGPNLSDNKSGQKV 485
E+ + + + K + E E D QS + R K+ + Q+
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ------------EGQRRRQEQ 735
Query: 486 SEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLE 545
E + + ELQ +++R + E++ + T + E KS+ G+ S
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ-----AEEKSERGRQRLSA---- 786
Query: 546 QFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLV--EPLSMIQFDDTAEPQKG 603
R RE +R AE + + L +E + E R E +QF + E +
Sbjct: 787 --RPPLREQR--ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR 842
Query: 604 KIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGK 663
+ + ++ + +E+ +E+ Q QL + R + T + L+ K
Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR-RRHTLYAKPALQEQLRK 901
Query: 664 SEQSNLEEFQEAIMAFLKQKI---DNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEE 720
EQ L+E +E + ++K + + +++ + +EEE L R E EK + + E
Sbjct: 902 -EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR--RQERER 958
Query: 721 YFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLS 780
++K K K+E+ +GE+P K+++ + + E LL
Sbjct: 959 QYRK---------DKKLQQKEEQLLGEEPEKRRRQEREKK----YREEEELQQEEEQLLR 1005
Query: 781 YESTDPVINNLIQMILAEIESERDIPTVSTVQKDHK---EKEKQ-RQEQYLQEGQEQMSG 836
E + + E +++ + +++ + E+E+Q R+E+ LQ+ +EQ+ G
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 837 MSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMK-EGKQEQQSQKQWQEEEMWKEEQKQ 895
+++ R L+ Y K E +E++ L+ + E ++ Q+ ++Q +EEE ++E++Q
Sbjct: 1066 ---EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122
Query: 896 ATPKQAEQEEKQKQRGQ--EEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEA 953
++ E+ +Q+ Q EEEE+ + Q L E +K + Q LE++ + ++Q+E
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE--LERQYREEEELQQEE 1180
Query: 954 KHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELE 999
+ L + ++ +E+++ R E+L+RQ + Q E Q +L+
Sbjct: 1181 EQLLREEQEKRRQERERQYREEEELQRQ--KRKQRYRDEDQRSDLK 1224
Score = 78.2 bits (191), Expect = 9e-14
Identities = 70/387 (18%), Positives = 194/387 (50%), Gaps = 25/387 (6%)
Query: 616 TITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEA 675
T+ KEE+ ++EE +Q R +E E R LE + + E+ E+ Q+
Sbjct: 251 TVLRKEEEKLQEEEPQRQ-----------RELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Query: 676 IMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAET--VTKIL 733
+ ++ + + +++ ++EE +R + E+ + + E+ ++ E ++
Sbjct: 300 L-----RREQQLRRKQEEERREQQEE--RREQQERREQQEERREQQLRREQEERREQQLR 352
Query: 734 RKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQ 793
R+ ++ ++E+Q+ + ++++ ++ + + + + Q
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 794 MILAE-IESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKE 852
+ + + E+ + ++ ++ E++R+EQ L+ QE+ LK++ ER+ +
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW-LKREEETERHEQER 471
Query: 853 HYEKISENWEEKKA--WLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQR 910
+++ + EE++ WL+++E ++ +Q +++ Q+ +EE+++ K+ E+EE+ +QR
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Query: 911 GQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQK 970
+ E++L + +R E+ ++ + + L E+ ++++ Q+E + R E+ +++ K
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 971 PERGLEDLERQIKTKDQMQMKETQPKE 997
E+ E LE+++K ++ ++++ + +E
Sbjct: 592 REQE-ERLEQRLKREEVERLEQEERRE 617
Score = 76.3 bits (186), Expect = 3e-13
Identities = 100/537 (18%), Positives = 245/537 (45%), Gaps = 53/537 (9%)
Query: 543 MLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEPQK 602
+L+ R+ + + F+ P +++ EP K + E R L E + + E +
Sbjct: 109 LLQDRRQEEDQRRFE--PRDRQLEEEPGQRRRQKRQEQE-RELAEGEEQSEKQERLEQRD 165
Query: 603 GKIKGKKHHISSGTITSKEEKTEEKEELT-------------KQVKSHQLVKSLSRVAKE 649
+ + ++ +EE+ E+E+L +Q++ +L++ + +E
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREE 225
Query: 650 TSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAE 709
+ R + + E+ +E ++ ++K+ + ++ + +EEE L++ E +
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE-EEPQRQRELQEEEEQLRKLERQ 284
Query: 710 KLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPI 769
+L + + E+ Q++ ++ RK ++ ++E+Q E+ +Q++ Q+
Sbjct: 285 ELRRERQEEEQQQQRLRRE-QQLRRKQEEERREQQ--EERREQQERREQQEERREQQLRR 341
Query: 770 SAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQE 829
+ L E + Q + E E ER + Q+ +E++ +R++Q +E
Sbjct: 342 EQEERREQQLRREQEE---ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 830 GQ-------EQMSGMSLKQQLLGERNLLKEHYE--------------KISENWEEKKAWL 868
Q + + +QQL E+ L +E E ++ EE++ WL
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 869 QMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEG 928
+ +E + + +++ Q+ + +EE+++ + E+EE+++Q+ + E++L + +R E+
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 929 TQKMKTQGLLLE--KENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKD 986
++ + + L + + Q+R+ Q+E + R EK E+++ E+ L+ Q + +D
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK--REQEERRD 576
Query: 987 QMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEK 1043
Q+ +K + + +++ + L R K ++V+R + + ++ LK E P+E+
Sbjct: 577 QL-LKREEERRQQRLKREQEERLEQRLKR--EEVERLEQEERREQRLKREE--PEEE 628
Score = 75.5 bits (184), Expect = 6e-13
Identities = 116/593 (19%), Positives = 258/593 (43%), Gaps = 69/593 (11%)
Query: 500 KKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLEQFRK---VKRESPF 556
+++R + + SE + + E +R+ L E + + LEQ R+ +KRE
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKR----------LEQERREQRLKREQE- 572
Query: 557 DKRPTAAEIKVEPTTESLDKEGKGEIRSLV--EPLSMIQFDDTAEPQKGKIKGKKHHISS 614
++R + + E + L +E + + + E + ++ ++ E Q+ K + +
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE-QRLKREEPEEERRQ 631
Query: 615 GTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQE 674
+ S+E++ +++L ++ + + + +E E E + + EQ EE QE
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 675 AIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVT--KI 732
+K +I + + ++ ++ R ++ + + EE ++ + +
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE 751
Query: 733 LRKYKDTKKEEQ---------VGEKPIKQKKVVSFMPGLHFQK-----SPISAKSESSTL 778
R ++ ++EEQ EK + ++ +S P L Q+ + + E L
Sbjct: 752 ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFL 811
Query: 779 LSYESTDPVINNLIQMI--LAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSG 836
E + + L +E E + Q+ +E++ +++Q + QEQ
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Query: 837 MSLKQQLLGERN----------LLKEHYEKISENWEEKKAWLQM--KEGKQEQQSQKQWQ 884
+ QL ER L+E K + +E++ LQ +E ++ Q+ ++Q++
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 885 EEEMWKEEQKQATPKQAEQEEKQKQRGQ--EEEELPKSSLQRLEEGTQKMKTQGLLLEKE 942
EEE ++E++Q ++ E+ +Q++ Q ++++L + Q L E +K + Q EK+
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE--REKK 989
Query: 943 NGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQ--PKELEK 1000
+ ++Q+E + L R E+ K ++ ++ ERQ + KD++Q +E Q +E EK
Sbjct: 990 YREEEELQQEEEQL---LREEREKRRR------QEWERQYRKKDELQQEEEQLLREEREK 1040
Query: 1001 MVIQ-------TPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPI 1046
+Q L + +L + + + +E +R + E L E+E +
Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Score = 73.9 bits (180), Expect = 2e-12
Identities = 145/830 (17%), Positives = 338/830 (40%), Gaps = 74/830 (8%)
Query: 296 EAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPG 355
E EK ++ R E E+ Q++ Q E+ E+ R ++ E+ Y + +
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL--ERQYREEEELQQEEEQLL 1184
Query: 356 PSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTP 415
Q R + + + K + DE QR + K +W+ + +
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLK---WQWEPEKENAVRDNKVY 1241
Query: 416 DLTELRQQPVASED--ISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSG 473
+Q ED + + ++ ++ G+ + D E + W++ + +
Sbjct: 1242 CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Query: 474 PNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEM-------KSFSEDKSKSPTEAKRKHLS 526
+ K + S+ + E + K++R+E + +++ + P + +
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 527 LTETKSQGGKSGTSMMMLEQ-FRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSL 585
E + + + G + EQ R+ +RE F K +++ + + L ++ + R
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ--QLRCQEREQQLRQDRDRKFREE 1419
Query: 586 VEPLSMIQFDDTAEPQKGKIKGKKHHIS-----SGTITSKEEKTEEKEELTKQVKSHQLV 640
+ LS + D ++ +++ ++ + K E+E+L ++ + QL
Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH 1479
Query: 641 KSLSRVAKETSESTRVL-ESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKE 699
+ R K E ++ + D K + L QE FL+++ + +K + +E
Sbjct: 1480 RQ-ERDRKFLEEEQQLRRQERDRKFREQELRS-QEPERKFLEEEQQLHRQQRQRKFLQEE 1537
Query: 700 EELLKRAEAEKLGII---KAKMEEYFQKVAETVTKILRKYKDTK--KEEQVGEKPIKQKK 754
++L ++ ++ K + EE ++ E ++ R+ +D K EEQ + +++K
Sbjct: 1538 QQLRRQERGQQRRQDRDRKFREEEQLRQEREE-QQLSRQERDRKFRLEEQKVRRQEQERK 1596
Query: 755 VVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDI----PTVST 810
+ L Q+ + E + + ++ + L E +R P +
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDR--KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654
Query: 811 VQKDH-----KEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKK 865
+++ ++++ + +EQ LQEG+EQ L++Q ER+ E+ E ++
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQ----LRRQ---ERDRKFREEEQQLRRQERER 1707
Query: 866 AWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRL 925
+LQ ++ + Q+ +++++EEE ++E +Q ++ E+ K + Q E + L+R
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQ 1767
Query: 926 EEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQ---------------- 969
E + + + L E+E Q+R + + K + R++ +E+Q
Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQ 1827
Query: 970 -----KPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSY 1024
+ +R ++ +RQ + ++Q +E +E +++ + + L++
Sbjct: 1828 LQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRR 1887
Query: 1025 EGKEFQRNLKTLENLPDE-KEPISITPPPSLQYSLPGALPISGQPLTKCI 1073
+ KE QR+ + E E K + P + Q++ ++P+ PL + I
Sbjct: 1888 QQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFA---SVPVRSSPLYEYI 1934
Score = 71.2 bits (173), Expect = 1e-11
Identities = 120/661 (18%), Positives = 279/661 (42%), Gaps = 54/661 (8%)
Query: 407 YTAQAERTPDLTELRQQPVASEDISED--STKDNVSLKKGDFYQEDETDEYQSWKRSHKK 464
Y A + T E R + E + +D +D + D E+E + + KR ++
Sbjct: 86 YYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE 145
Query: 465 ---ATYVYETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKS----P 517
A ++ + + Q+ E Q E Q +++R E + K P
Sbjct: 146 RELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP 205
Query: 518 TEAKRKHLSLTETKSQGGKSGTSMMMLEQFR--KVKRESPFDKRPTAAEIKVEPTTESLD 575
E + + L E + +G + Q R + + E + KR T K E + +
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLR-KEEEKLQEEE 264
Query: 576 KEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSK--EEKTEEKEELTKQ 633
+ + E++ E L ++ + ++ + + ++ + K EE+ E++EE +Q
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 634 VKSHQLVKS-----LSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIG 688
+ + + L R +E E E + + EQ E +E +Q++
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR---EQQLRREQ 381
Query: 689 KAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748
+ ++ + +E++L + + + ++ + + LR+ + ++E+Q+ +
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQ-------------LRREQQLRREQQLRRE 428
Query: 749 PIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTV 808
+++ Q+ + L E T+ + L + E
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 809 STVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGER--NLLKEHYEKISENWEEKKA 866
++++ + ++++R+EQ L+ QE+ LK+Q ER L+ + E E ++
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 867 WLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQ----RGQE---EEELPK 919
L+ +E K+ +Q ++ E+ K EQ++ + ++EE+++Q R QE E+ L +
Sbjct: 549 LLKREEEKRLEQERR----EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 920 SSLQRLEE---GTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLE 976
++RLE+ Q++K + E+ ++ ++E + RR ++ + +Q+ +R E
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Query: 977 D--LERQIKTKDQMQMKETQ-PKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNL 1033
+ LE+++K + + + +E + +E ++ + + P+W+ L+ + + K + R
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 1034 K 1034
K
Sbjct: 725 K 725
>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular protein
isoform 1 [Homo sapiens]
Length = 1635
Score = 92.0 bits (227), Expect = 6e-18
Identities = 175/801 (21%), Positives = 295/801 (36%), Gaps = 134/801 (16%)
Query: 955 HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006
HLGP E P+ E+L + T D +P++ +K+ Q
Sbjct: 86 HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQER 142
Query: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISG 1066
+ +SP K + KD + + E ++ L +K+ + S PG+LP
Sbjct: 143 LPVSP--KKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQ-NEYSSTDTPYPGSLP--- 196
Query: 1067 QPLTKCIHLTPQQAQEVGITLTPQQAQAQGI-TLTLQQAQELGIPLTPQQAQALEILFTP 1125
L P +++VG + + + Q TL Q+ L Q Q LE +
Sbjct: 197 PELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS 256
Query: 1126 QQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------------- 1159
Q +A P P ++ ++ +TL P +DQA P I++
Sbjct: 257 MQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 1160 ----TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQAL 1203
++Q Q+ I P QQ + P+ P + EL I P+ P ++
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPR- 371
Query: 1204 RVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQEL 1263
V +P Q + G P P+ + Q L P + + +T+ + E+
Sbjct: 372 EVESSPTQQETPGQP--PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
Query: 1264 GIPLTPQQA----QALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPF---- 1315
G L Q+A G + P Q G PL P+ ++ G PL +Q + P
Sbjct: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQSPEPINN 488
Query: 1316 -TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMP 1374
P Q PQ A+ E +LT Q+A P T + + + P+H+ +
Sbjct: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSH---LT 540
Query: 1375 LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEIT 1434
T Q +LG +TP+ + + T ++ TP Q + +P T
Sbjct: 541 QATVQPLDLGFTITPESKTEVELSPTMKE--------TPTQPPKKVVPQLRVYQGVTNPT 592
Query: 1435 LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIP 1494
QAQ P Q +LG+T+TP+ E+G P++ ++ P+ E+ +P
Sbjct: 593 PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRT------IVSPKHPEVTLP 646
Query: 1495 LTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELGIP----- 1542
Q Q Q + Q +LG +TP + + AL PP E+ +P
Sbjct: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
Query: 1543 ------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1596
LT VQ L + L E+ +P + T Q +LG+ + P+
Sbjct: 707 QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGLAIIPEPT 760
Query: 1597 QELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNA 1656
E G ++ A P + Q L SLT +T P + + + +
Sbjct: 761 TETGHSTALEKTTAP----RPDRVQTLHRSLTE-------VTGPPTELEPAQDSLVQSES 809
Query: 1657 WVSAVTLTSEQTHALESPMNL 1677
+ LT+ + H + N+
Sbjct: 810 YTQNKALTAPEEHKASTSTNI 830
>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular protein
isoform 2 [Homo sapiens]
Length = 1700
Score = 92.0 bits (227), Expect = 6e-18
Identities = 175/801 (21%), Positives = 295/801 (36%), Gaps = 134/801 (16%)
Query: 955 HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006
HLGP E P+ E+L + T D +P++ +K+ Q
Sbjct: 86 HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQER 142
Query: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISG 1066
+ +SP K + KD + + E ++ L +K+ + S PG+LP
Sbjct: 143 LPVSP--KKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQ-NEYSSTDTPYPGSLP--- 196
Query: 1067 QPLTKCIHLTPQQAQEVGITLTPQQAQAQGI-TLTLQQAQELGIPLTPQQAQALEILFTP 1125
L P +++VG + + + Q TL Q+ L Q Q LE +
Sbjct: 197 PELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS 256
Query: 1126 QQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------------- 1159
Q +A P P ++ ++ +TL P +DQA P I++
Sbjct: 257 MQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 1160 ----TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQAL 1203
++Q Q+ I P QQ + P+ P + EL I P+ P ++
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPR- 371
Query: 1204 RVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQEL 1263
V +P Q + G P P+ + Q L P + + +T+ + E+
Sbjct: 372 EVESSPTQQETPGQP--PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
Query: 1264 GIPLTPQQA----QALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPF---- 1315
G L Q+A G + P Q G PL P+ ++ G PL +Q + P
Sbjct: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQSPEPINN 488
Query: 1316 -TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMP 1374
P Q PQ A+ E +LT Q+A P T + + + P+H+ +
Sbjct: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSH---LT 540
Query: 1375 LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEIT 1434
T Q +LG +TP+ + + T ++ TP Q + +P T
Sbjct: 541 QATVQPLDLGFTITPESKTEVELSPTMKE--------TPTQPPKKVVPQLRVYQGVTNPT 592
Query: 1435 LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIP 1494
QAQ P Q +LG+T+TP+ E+G P++ ++ P+ E+ +P
Sbjct: 593 PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRT------IVSPKHPEVTLP 646
Query: 1495 LTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELGIP----- 1542
Q Q Q + Q +LG +TP + + AL PP E+ +P
Sbjct: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
Query: 1543 ------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1596
LT VQ L + L E+ +P + T Q +LG+ + P+
Sbjct: 707 QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGLAIIPEPT 760
Query: 1597 QELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNA 1656
E G ++ A P + Q L SLT +T P + + + +
Sbjct: 761 TETGHSTALEKTTAP----RPDRVQTLHRSLTE-------VTGPPTELEPAQDSLVQSES 809
Query: 1657 WVSAVTLTSEQTHALESPMNL 1677
+ LT+ + H + N+
Sbjct: 810 YTQNKALTAPEEHKASTSTNI 830
>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
Length = 1700
Score = 92.0 bits (227), Expect = 6e-18
Identities = 175/801 (21%), Positives = 295/801 (36%), Gaps = 134/801 (16%)
Query: 955 HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006
HLGP E P+ E+L + T D + +P++ +K+ Q
Sbjct: 86 HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQER 142
Query: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISG 1066
+ +SP K + KD + + E + L +K+ + S PG+LP
Sbjct: 143 LPVSP--KKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQ-NEYSSTDTPYPGSLP--- 196
Query: 1067 QPLTKCIHLTPQQAQEVGITLTPQQAQAQGI-TLTLQQAQELGIPLTPQQAQALEILFTP 1125
L P +++VG + + + Q TL Q+ L Q Q LE +
Sbjct: 197 PELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS 256
Query: 1126 QQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------------- 1159
Q +A P P ++ ++ +TL P +DQA P I++
Sbjct: 257 MQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 1160 ----TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQAL 1203
++Q Q+ I P QQ + P+ P + EL I P+ P ++
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPR- 371
Query: 1204 RVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQEL 1263
V +P Q + G P P+ + Q L P + + +T+ + E+
Sbjct: 372 EVESSPTQQETPGQP--PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
Query: 1264 GIPLTPQQA----QALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPF---- 1315
G L Q+A G + P Q G PL P+ ++ G PL +Q + P
Sbjct: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQSPEPINN 488
Query: 1316 -TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMP 1374
P Q PQ A+ E +LT Q+A P T + + + P+H+ +
Sbjct: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSH---LT 540
Query: 1375 LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEIT 1434
T Q +LG +TP+ + + T ++ TP Q + +P T
Sbjct: 541 QATVQPLDLGFTITPESKTEVELSPTMKE--------TPTQPPKKVVPQLRVYQGVTNPT 592
Query: 1435 LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIP 1494
QAQ P Q +LG+T+TP+ E+G P++ ++ P+ E+ +P
Sbjct: 593 PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRT------IVSPKHPEVTLP 646
Query: 1495 LTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELGIP----- 1542
Q Q Q + Q +LG +TP + + AL PP E+ +P
Sbjct: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
Query: 1543 ------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1596
LT VQ L + L E+ +P + T Q +LG+ + P+
Sbjct: 707 QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGLAIIPEPT 760
Query: 1597 QELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNA 1656
E G ++ A P + Q L SLT +T P + + + +
Sbjct: 761 TETGHSTALEKTTAP----RPDRVQTLHRSLTE-------VTGPPTELEPAQDSLVQSES 809
Query: 1657 WVSAVTLTSEQTHALESPMNL 1677
+ LT+ + H + N+
Sbjct: 810 YTQNKALTAPEEHKASTSTNI 830
>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
Length = 957
Score = 91.7 bits (226), Expect = 8e-18
Identities = 67/374 (17%), Positives = 134/374 (35%), Gaps = 6/374 (1%)
Query: 1175 QAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQAQALGITLTLQ 1234
+ QA P P +P P +Q L+ L + + T + + + T+
Sbjct: 27 EMQAPNAPGLPADVPGSDVPQGPSDSQILQ-GLCASEGPSTSVLPTSAEGPSTFVPPTIS 85
Query: 1235 QAQQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQALGITLTPKQAQELGIPLNPQ 1294
+A T + + TP + P T + +TL + + P
Sbjct: 86 EASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSS 145
Query: 1295 QAQTLGIPLTPKQAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQ 1354
+ + +P T + + +P TP + + +P T + + + TP + + + T
Sbjct: 146 EEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPG 205
Query: 1355 QAQELGIPLTPQHAQALGMPLTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQ 1414
+ +PL + + T + +P T + + +P T + +P TP
Sbjct: 206 EGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPG 265
Query: 1415 QAQELGIPFTPQQAQAQEITLTPQQAQ--ALGMPLTAQQAQELGITLTPQQAQELGIPLT 1472
+ + P + Q I+L P + + + +P TA + + T + +P T
Sbjct: 266 EGPSTSV--LPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPT 323
Query: 1473 PQQAQALGIPLIPPQAQELGIPLTPQQAQALGILLIPPQAQELGIPLTPQQAQALGIPLI 1532
P + +P + +P TP + + +L IP + +P T +P
Sbjct: 324 PGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPT 383
Query: 1533 PPQ-AQELGIPLTP 1545
P + A L P P
Sbjct: 384 PGEGASTLVQPTAP 397
Score = 85.5 bits (210), Expect = 6e-16
Identities = 61/383 (15%), Positives = 128/383 (33%), Gaps = 1/383 (0%)
Query: 1259 QVQELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQ 1318
++Q P P + P +Q L + T +P + + P +
Sbjct: 27 EMQAPNAPGLPADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISE 86
Query: 1319 QAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQ 1378
+ A G P T + + TP + + P T + + L + P T+
Sbjct: 87 ASSASGQP-TISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSS 145
Query: 1379 QAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQ 1438
+ +P T + + +P T + +P T + + TP + + + TP
Sbjct: 146 EEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPG 205
Query: 1439 QAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQ 1498
+ +PL A + + TP + +P T + + +P + +P TP
Sbjct: 206 EGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPG 265
Query: 1499 QAQALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPP 1558
+ + +L Q + + T + + +P + + T + + +P P
Sbjct: 266 EGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPG 325
Query: 1559 QAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQ 1618
+P T + + +P TP + + P + +P T +P TP
Sbjct: 326 GGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPG 385
Query: 1619 QAQALGISLTPQQAQAQGITLTP 1641
+ + + T + P
Sbjct: 386 EGASTLVQPTAPDGPGSSVLPNP 408
Score = 77.4 bits (189), Expect = 2e-13
Identities = 62/363 (17%), Positives = 122/363 (33%), Gaps = 21/363 (5%)
Query: 1307 QAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQ 1366
+ QA P P +P P +Q + + +P + + P +
Sbjct: 27 EMQAPNAPGLPADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISE 86
Query: 1367 HAQALGMPLTTQQAQELGIPLTPQQAQALGMP-----------LTTQQAQELGIPLTPQQ 1415
+ A G P ++ +P + G P L + + P T +
Sbjct: 87 ASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSE 146
Query: 1416 AQELGIPFTPQQAQAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQ 1475
+P T + + + TP + + +P TA + + TP + + TP +
Sbjct: 147 EPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGE 206
Query: 1476 AQALGIPLIPPQAQELGIPLTPQQAQALGILLIPPQAQE---LGIPLTPQQAQALGIPLI 1532
+PL + + TP + + +PP A E +P T + + +P
Sbjct: 207 GPGTSVPLAATEGLSTSVQATPDEGPSTS---VPPTATEGLSTPVPPTRDEGPSTSVPAT 263
Query: 1533 PPQAQELGIPLTPQQVQALGIPLIPPQAQ--ELEIPLTPQQAQALGIPLTPQQAQELGIP 1590
P + + P I L+P + + +P T + + + T + +P
Sbjct: 264 PGEGPSTSV--LPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVP 321
Query: 1591 LTPQQAQELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVP 1650
TP +P T + + +P TP + + + P + + + T VP
Sbjct: 322 PTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVP 381
Query: 1651 ITP 1653
TP
Sbjct: 382 PTP 384
Score = 74.3 bits (181), Expect = 1e-12
Identities = 67/377 (17%), Positives = 132/377 (35%), Gaps = 36/377 (9%)
Query: 1109 IPLTPQQAQALEILFT---------PQQAQALGIPLTPQQTQVQGITLTPQQDQAPGISL 1159
+P P +Q L+ L P A+ + P ++ + P + PG S+
Sbjct: 45 VPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSV 104
Query: 1160 TTQQAQKLGI--PLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGI 1217
++ L P T + + L + + P T + + V T + +
Sbjct: 105 LPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSL 164
Query: 1218 PLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQALGI 1277
P TP + + + T + + TP + + + TP + +PL + + +
Sbjct: 165 PPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSV 224
Query: 1278 TLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQAQALGIPLTPQQAQTQEI 1337
TP + +P P + L P+ P T + + +P TP + + +
Sbjct: 225 QATPDEGPSTSVP--PTATEGLSTPVPP----------TRDEGPSTSVPATPGEGPSTSV 272
Query: 1338 TLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQAQELGIPLTPQQAQALGM 1397
Q++ + T + +P T + + T + +P TP G
Sbjct: 273 LPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTP------GG 326
Query: 1398 PLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQAQALGMPLTAQQAQELGI 1457
L+T +P T + +P TP + + + P + + +P TA + +
Sbjct: 327 GLST------SVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSV 380
Query: 1458 TLTP-QQAQELGIPLTP 1473
TP + A L P P
Sbjct: 381 PPTPGEGASTLVQPTAP 397
Score = 73.9 bits (180), Expect = 2e-12
Identities = 59/372 (15%), Positives = 121/372 (32%), Gaps = 2/372 (0%)
Query: 1127 QAQALGIPLTPQQTQVQGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQ 1186
+ QA P P + P Q L + + T + + +P T
Sbjct: 27 EMQAPNAPGLPADVPGSDVPQGPSDSQILQ-GLCASEGPSTSVLPTSAEGPSTFVPPTIS 85
Query: 1187 QAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQ 1246
+A T + V TP + P T + +TL + + P T
Sbjct: 86 EASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSS 145
Query: 1247 QAQALGITLTPKQVQELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPK 1306
+ + + T +V +P TP + + + T + + P + + + TP
Sbjct: 146 EEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPG 205
Query: 1307 QAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQ 1366
+ +P + + + TP + + + T + + +P T + +P TP
Sbjct: 206 EGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPG 265
Query: 1367 HAQALGMPLTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQ 1426
+ + Q + + T + + +P T + + T + +P TP
Sbjct: 266 EGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPG 325
Query: 1427 QAQAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPP 1486
+ + T + + +P T + + P + +P T +P P
Sbjct: 326 GGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPG 385
Query: 1487 Q-AQELGIPLTP 1497
+ A L P P
Sbjct: 386 EGASTLVQPTAP 397
Score = 73.6 bits (179), Expect = 2e-12
Identities = 61/376 (16%), Positives = 133/376 (35%), Gaps = 14/376 (3%)
Query: 1052 PSLQYSLPGALPISGQPLTKCIH-LTPQQAQEVGITLTPQQAQAQGITLTLQQAQELGIP 1110
P L +PG+ G ++ + L + + T + + + T+ +A
Sbjct: 34 PGLPADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQ 93
Query: 1111 LTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQDQAPGISLTTQQAQKLGIP 1170
T + +L TP + + P T + +TL + + T+ + +P
Sbjct: 94 PTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVP 153
Query: 1171 LTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQAQALGIT 1230
T + + +P TP + +P T + + V TP + + TP + +
Sbjct: 154 PTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVP 213
Query: 1231 LTLQQAQQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQALGITLTPKQAQELGIP 1290
L + + TP + + + T + +P T + + + TP + +
Sbjct: 214 LAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVL 273
Query: 1291 LNPQQAQTLGIPLTPKQAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMP 1350
Q++ + T + + +P T + + + T + + + TP + +P
Sbjct: 274 PAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVP 333
Query: 1351 LTTQQAQELGIPLTPQHAQALGMPLTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIP 1410
T + +P TP + + +P+ P + + +P T + +P
Sbjct: 334 PTATEELSTSVPPTPGEGPSTSV-----------LPI-PGEGLSTSVPPTASDGSDTSVP 381
Query: 1411 LTP-QQAQELGIPFTP 1425
TP + A L P P
Sbjct: 382 PTPGEGASTLVQPTAP 397
Score = 72.0 bits (175), Expect = 6e-12
Identities = 61/331 (18%), Positives = 118/331 (35%), Gaps = 19/331 (5%)
Query: 1039 LPDEKEPISITPPPSLQY--SLPGALPISGQPLTKCIHLTPQQAQEVGITLTPQQAQAQG 1096
LP E S PP++ S G IS P T + TP + T +
Sbjct: 69 LPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLP-TPSEGLSTSGPPTISKGLCTS 127
Query: 1097 ITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQDQAPG 1156
+TL + + P T + + + T + + +P TP + + T + +
Sbjct: 128 VTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTS 187
Query: 1157 ISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELG 1216
+ T + + TP + +PL + + TP + + S+ P + L
Sbjct: 188 VVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPS--TSVPPTATEGLS 245
Query: 1217 IPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQALG 1276
P+ P T + +P TP + + + P I L P + +
Sbjct: 246 TPVPP----------TRDEGPSTSVPATPGEGPSTSV--LPAASDGQSISLVPTRGKGSS 293
Query: 1277 ITLTPKQAQELGIPLNPQ--QAQTLGIPLTPKQAQALGIPFTPQQAQALGIPLTPQQAQT 1334
++ P + L + P + + +P TP + +P T + + +P TP + +
Sbjct: 294 TSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPS 353
Query: 1335 QEITLTPQQAQALGMPLTTQQAQELGIPLTP 1365
+ P + + +P T + +P TP
Sbjct: 354 TSVLPIPGEGLSTSVPPTASDGSDTSVPPTP 384
Score = 68.6 bits (166), Expect = 7e-11
Identities = 98/479 (20%), Positives = 156/479 (32%), Gaps = 99/479 (20%)
Query: 1475 QAQALGIPLIPPQAQELGIPLTPQQAQALGIL---------LIPPQAQELGIPLTPQQAQ 1525
+ QA P +P +P P +Q L L ++P A+ + P ++
Sbjct: 27 EMQAPNAPGLPADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISE 86
Query: 1526 ALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQAQEL--EIPLTPQQAQALGIPLTPQQ 1583
A P ++ G + P + L P ++ L + L + + P T +
Sbjct: 87 ASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSE 146
Query: 1584 AQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQ 1643
+P T + +P TP + + +P T + + + TP + + + TP +
Sbjct: 147 EPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGE 206
Query: 1644 AQALGVPITPVNAWVSAVTLTSEQTHALESPMNLEQAQEQLLKLGVPLTLDKAHTLGSPL 1703
VP+ ++V T ++ + P + L VP T D+ + P
Sbjct: 207 GPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEG----LSTPVPPTRDEGPSTSVPA 262
Query: 1704 TLKQVQWSHRPFQKSKASLPTGQSIISRLSPSLRLSLASSAPTAEKSSIFGVSSTPLQIS 1763
T + P + GQSI S PT K S V T +
Sbjct: 263 TPGE-----GPSTSVLPAASDGQSI-------------SLVPTRGKGSSTSVPPTATE-- 302
Query: 1764 RVPLNQGPFAPGKPLEMGILSEPGKLGAPQTLRSSGQTLVYGGQSTSAQFPAPQAPPSPG 1823
G STS Q P+ G
Sbjct: 303 ------------------------------------------GLSTSVQ-------PTAG 313
Query: 1824 QLPISRAPPTPGQPFIAGVPPTSGQIPSLWAPLSPGQPLVPEASSIPGDLLESGPLTFSE 1883
+ + PPTPG VPPT+ + S P +PG+ IPG+ L +
Sbjct: 314 EGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLST------- 366
Query: 1884 QLQEFQPPATAEQSPYLQAPSTPGQHLATW---TLPGRASSLWIPPTSRHPPTLWPSPA 1939
P TA P TPG+ +T T P S +P P TL+ S A
Sbjct: 367 -----SVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSA 420
Score = 63.9 bits (154), Expect = 2e-09
Identities = 49/280 (17%), Positives = 101/280 (36%), Gaps = 10/280 (3%)
Query: 1400 TTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQAQALGMPLTAQQAQELGITL 1459
T+ + +P T +A T + + TP + + P T + +TL
Sbjct: 71 TSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTL 130
Query: 1460 TPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQAQALGILLIPPQAQE---LG 1516
+ + P T + + +P + +P TP + + + PP A E
Sbjct: 131 AASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSV---PPTAYEGPSTS 187
Query: 1517 IPLTPQQAQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQAQELEIPLTPQQAQALG 1576
+ TP + + + P + +PL + + + P + +P T + +
Sbjct: 188 VVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTP 247
Query: 1577 IPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQG 1636
+P T + +P TP + + P + Q I L P + + S+ P +
Sbjct: 248 VPPTRDEGPSTSVPATPGEGPSTSV--LPAASDGQSISLVPTRGKGSSTSVPPTATEGLS 305
Query: 1637 ITLTPQ--QAQALGVPITPVNAWVSAVTLTSEQTHALESP 1674
++ P + + VP TP ++V T+ + + P
Sbjct: 306 TSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVP 345
Score = 57.8 bits (138), Expect = 1e-07
Identities = 65/274 (23%), Positives = 104/274 (37%), Gaps = 48/274 (17%)
Query: 1723 PTGQSIISRLSPSLRLSLASSAPTAEKSSIF---GVSSTPLQISRVPLNQGPFAPGKPLE 1779
P+ I+ L S S + +AE S F +S + +++GP P
Sbjct: 49 PSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLPTP 108
Query: 1780 MGILSEPGKLGAPQTLRSSGQTLVYGGQSTS-----AQFPAPQAPPSPGQLPISRAPPTP 1834
LS G + L +S G++TS ++ P+ PP+ ++P + PPTP
Sbjct: 109 SEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTP 168
Query: 1835 GQPFIAGVPPTS------------------------GQIPSLWAPLSPGQPLVPEASSIP 1870
G+ VPPT+ G+ P PL+ + L + P
Sbjct: 169 GEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATP 228
Query: 1871 GD-LLESGPLTFSEQLQEFQPPATAEQSPYLQAPSTPGQHLATWTLP------------- 1916
+ S P T +E L PP T ++ P P+TPG+ +T LP
Sbjct: 229 DEGPSTSVPPTATEGLSTPVPP-TRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPT 287
Query: 1917 -GRASSLWIPPTSRHPPTLWPSPAPGKPQKSWSP 1949
G+ SS +PPT+ + P G+ + P
Sbjct: 288 RGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVP 321
Score = 55.8 bits (133), Expect = 5e-07
Identities = 43/265 (16%), Positives = 92/265 (34%), Gaps = 16/265 (6%)
Query: 1043 KEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQQAQEVGITLTPQQAQAQGITLTLQ 1102
+EP + PP + + P G+ + + T + + TP + + + T
Sbjct: 146 EEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPG 205
Query: 1103 QAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQDQAPGISLTTQ 1162
+ +PL + + + TP + + +P P T+ + P +D+ P S+
Sbjct: 206 EGPGTSVPLAATEGLSTSVQATPDEGPSTSVP--PTATEGLSTPVPPTRDEGPSTSVPAT 263
Query: 1163 QAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQ--QAQELGIPLT 1220
+ + P + I L P + + + P + L S+ P + +P T
Sbjct: 264 PGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPT 323
Query: 1221 PQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQV------------QELGIPLT 1268
P + + T + +P TP + + + P + + +P T
Sbjct: 324 PGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPT 383
Query: 1269 PQQAQALGITLTPKQAQELGIPLNP 1293
P + + + T + NP
Sbjct: 384 PGEGASTLVQPTAPDGPGSSVLPNP 408
Score = 37.7 bits (86), Expect = 0.13
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 1/174 (0%)
Query: 1035 TLENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQQAQEVGITLTPQQAQA 1094
+++ PDE S+ P + S P P + + + TP + + Q+
Sbjct: 223 SVQATPDEGPSTSVPPTATEGLSTP-VPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQS 281
Query: 1095 QGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQDQA 1154
+ T + +P T + + + T + + +P TP + T ++ +
Sbjct: 282 ISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELS 341
Query: 1155 PGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLT 1208
+ T + + P + + +P T + +P TP + + V T
Sbjct: 342 TSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPT 395
>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
sapiens]
Length = 1634
Score = 91.3 bits (225), Expect = 1e-17
Identities = 175/801 (21%), Positives = 294/801 (36%), Gaps = 134/801 (16%)
Query: 955 HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006
HLGP E P+ E+L + T D +P++ +K+ Q
Sbjct: 86 HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQER 142
Query: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISG 1066
+ +SP K + KD + + E + L +K+ + S PG+LP
Sbjct: 143 LPVSP--KKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQ-NEYSSTDTPYPGSLP--- 196
Query: 1067 QPLTKCIHLTPQQAQEVGITLTPQQAQAQGI-TLTLQQAQELGIPLTPQQAQALEILFTP 1125
L P +++VG + + + Q TL Q+ L Q Q LE +
Sbjct: 197 PELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS 256
Query: 1126 QQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------------- 1159
Q +A P P ++ ++ +TL P +DQA P I++
Sbjct: 257 MQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 1160 ----TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQAL 1203
++Q Q+ I P QQ + P+ P + EL I P+ P ++
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESSR- 371
Query: 1204 RVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQEL 1263
V +P Q + G P P+ + Q L P + + +T+ + E+
Sbjct: 372 EVESSPTQQETPGQP--PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
Query: 1264 GIPLTPQQA----QALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPF---- 1315
G L Q+A G + P Q G PL P+ ++ G PL +Q + P
Sbjct: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQSPEPINN 488
Query: 1316 -TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMP 1374
P Q PQ A+ E +LT Q+A P T + + + P+H+ +
Sbjct: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSH---LT 540
Query: 1375 LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEIT 1434
T Q +LG +TP+ + + T ++ TP Q + +P T
Sbjct: 541 QATVQPLDLGFTITPESMTEVELSPTMKE--------TPTQPPKKVVPQLRVYQGVTNPT 592
Query: 1435 LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIP 1494
QAQ P Q +LG+T+TP+ E+G P++ ++ P+ E+ +P
Sbjct: 593 PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRT------IVSPKHPEVTLP 646
Query: 1495 LTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELGIP----- 1542
Q Q Q + Q +LG +TP + + AL PP E+ +P
Sbjct: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
Query: 1543 ------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1596
LT VQ L + L E+ +P + T Q +LG+ + P+
Sbjct: 707 QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQLPDLGLAIIPEPT 760
Query: 1597 QELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNA 1656
E G ++ A P + Q L SLT +T P + + + +
Sbjct: 761 TETGHSTALEKTTAP----RPDRVQTLHRSLTE-------VTGPPTELEPAQDSLVQSES 809
Query: 1657 WVSAVTLTSEQTHALESPMNL 1677
+ LT+ + H + N+
Sbjct: 810 YTQNKALTAPEEHKASTSTNI 830
>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
sapiens]
Length = 870
Score = 90.9 bits (224), Expect = 1e-17
Identities = 175/759 (23%), Positives = 286/759 (37%), Gaps = 141/759 (18%)
Query: 955 HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006
HLGP E P+ E+L + T D + +P++ +K+ Q
Sbjct: 86 HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQER 142
Query: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPI------SITPPPSLQYSLPG 1060
+ +SP K + KD + + E + L +K+ + + TP PS SLP
Sbjct: 143 LPVSP--KKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPS---SLPP 197
Query: 1061 ALPI-SGQPLTKCIHLTPQQAQEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQAL 1119
L + S +P + P Q T P+ TL Q+ L Q Q L
Sbjct: 198 ELRVKSDEPPGPSEQVGPSQFHLEPETQNPE-------TLEDIQSSSLQQEAPAQLPQLL 250
Query: 1120 EILFTPQQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------- 1159
E + Q +A P P ++ ++ +TL P +DQA P I++
Sbjct: 251 EEEPSSMQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVT 307
Query: 1160 ----------TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTP 1197
++Q Q+ I P QQ + P++P + EL I P+ P
Sbjct: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPME-HELSISEQQQPVQP 366
Query: 1198 QQA-QALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLT 1256
++ + + SLT Q+ G P P+ + Q L P + + +T+
Sbjct: 367 SESSREVESSLTQQETP--GQP--PEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIA 422
Query: 1257 PKQVQELGIPLTPQQAQAL----GITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALG 1312
+ E+G L Q+A A G + P Q G PL P+ ++ G PL +Q +
Sbjct: 423 AEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQ 481
Query: 1313 IPF-----TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQH 1367
P P Q PQ A+ E +LT Q+A P T + + + P+H
Sbjct: 482 SPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEH 536
Query: 1368 AQALGMPLTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQ 1427
+ + T Q +LG +TP+ + + T ++ TP Q + +P
Sbjct: 537 SH---LTQATVQPLDLGFTITPESMTEVELSPTMKE--------TPTQPPKKVVPQLRVY 585
Query: 1428 AQAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQ 1487
T QAQ P Q +LG+T+TP+ E+G P++ ++ P+
Sbjct: 586 QGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRT------IVSPK 639
Query: 1488 AQELGIPLTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELG 1540
E+ +P Q Q Q + Q +LG +TP + + AL PP E+
Sbjct: 640 HPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVT 699
Query: 1541 IP-----------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGI 1589
+P LT VQ L + L E+ +P + T Q +LG+
Sbjct: 700 LPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGL 753
Query: 1590 PLTPQQAQELGIPLTPQQAQAQGIPLTPQQAQALGISLT 1628
+ P+ E G ++ A P + Q+L SLT
Sbjct: 754 AIIPEPTTETGHSTALEKTTAP----HPDRVQSLHRSLT 788
Score = 60.8 bits (146), Expect = 1e-08
Identities = 136/626 (21%), Positives = 239/626 (38%), Gaps = 117/626 (18%)
Query: 1111 LTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQD-QAPGISLTTQQAQKLG- 1168
L ++AQ LE + P Q + PL P ++ + P++ AP + LG
Sbjct: 32 LLVKEAQPLEWVKDPLQLTSN--PLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGP 89
Query: 1169 -----IPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQ 1223
+P PQ++ +P PL P+Q A + L + + + +P++P++
Sbjct: 90 SASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKK 149
Query: 1224 -----AQALGITLTLQQAQQLGIPLTPQQA--QALGITLTP------------------- 1257
AQ + + A+QL P + +Q T TP
Sbjct: 150 LKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGP 209
Query: 1258 -KQVQELGIPLTP--QQAQALGITLTPKQAQELGIPL------NPQQAQTLGIPLTPKQA 1308
+QV L P Q + L + QE L P Q L P+ +
Sbjct: 210 SEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESS 269
Query: 1309 -QALGIPFTPQQAQALG-------IPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELG 1360
++L +P Q G +P + E+T+T + ++Q QE
Sbjct: 270 MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETE---SSQAQQETP 326
Query: 1361 IPLTPQHAQALGMPLTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQA-QEL 1419
I P+ + P TQQ + P++P + + L+ + Q+ P+ P ++ +E+
Sbjct: 327 IQF-PEEVE----PSATQQEAPIEPPVSPMEHE-----LSISEQQQ---PVQPSESSREV 373
Query: 1420 GIPFTPQQAQAQ-----EITLTP---QQAQALGMPLTAQQAQELGITLTPQQAQELGIPL 1471
T Q+ Q E+T++P Q L P + + ++ +T+ + + E+G L
Sbjct: 374 ESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSL 433
Query: 1472 TPQQAQAL----GIPLIPPQAQELGIPLTPQQAQALGILLIPPQAQ-ELGIPLT---PQQ 1523
Q+A A G + PP Q G PL P+ ++ G L + + + P+ P
Sbjct: 434 VHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
Query: 1524 AQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQAQELEIPLTPQQAQA--------- 1574
Q P A+E LT Q+ P P+ + + P+ +
Sbjct: 494 TQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
Query: 1575 LGIPLTPQQAQELGIPLT----PQQAQELGIPL----------TPQQAQAQGIPLTPQ-- 1618
LG +TP+ E+ + T P Q + +P TP Q QAQ P++P
Sbjct: 549 LGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH-PVSPSVT 607
Query: 1619 -QAQALGISLTPQQAQAQGITLTPQQ 1643
Q LG+++TP+ G + P++
Sbjct: 608 VQLLDLGLTITPEPTTEVGHSTAPKR 633
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 90.5 bits (223), Expect = 2e-17
Identities = 101/494 (20%), Positives = 226/494 (45%), Gaps = 73/494 (14%)
Query: 576 KEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQ-- 633
K+ +GE R L+ L K G+ S T K++ EELTK+
Sbjct: 215 KQLEGEARDLISRLH----------DSWKFAGELEQALSAVATQKKKADRYIEELTKERD 264
Query: 634 -----------------VKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAI 676
K+ +L + L V E SE ++ K E++ L Q+ +
Sbjct: 265 ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQL 324
Query: 677 MAFLKQKIDNIGKAFDKKTVP-----KEEEL---LKRAEAEKLGIIKAKMEEYFQKVAET 728
A + D++GK + +E EL L + + EK+ + K++E+ +K+ E
Sbjct: 325 QA----EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 380
Query: 729 VTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVI 788
KI ++EE++ E+ K ++ M ++K + E + +E + +
Sbjct: 381 EEKI------REQEEKIREQEEKMRRQEEMM----WEKEEKMRRQEE---MMWEKEEKM- 426
Query: 789 NNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERN 848
+M+ + E R++ Q+ +E+E++RQE+ ++ +EQ + ++ +
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE--EKIREQEKRQEQEAKMWRQEE 484
Query: 849 LLKEHYEKISENWEEKKAWLQ---MKEGKQEQQSQKQWQEEEMWKEE-----------QK 894
++E EKI E +E+K W Q + E ++ ++ +K+ ++EEMW++E QK
Sbjct: 485 KIREQEEKIRE--QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 895 QATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAK 954
+ +Q E+ KQ+++ +EE +++ E +K+ Q + ++ ++R+ +++ +
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Query: 955 HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWK 1014
+ ++ K ++ E+ E E+ + +++M+ +E + +E EK + + + + +
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 1015 SVLKDVQRSYEGKE 1028
+ + ++ +E +E
Sbjct: 663 MMQEQEEKMWEQEE 676
Score = 82.8 bits (203), Expect = 4e-15
Identities = 95/468 (20%), Positives = 221/468 (47%), Gaps = 60/468 (12%)
Query: 609 KHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSN 668
++ I+ + K K +EK +L + KS ++ ++ + ++ + +L ++E +
Sbjct: 272 RNTITDEELKEKNAKLQEKLQLVESEKS-EIQLNVKELKRKLERAKLLLPQQQLQAEADH 330
Query: 669 LEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAET 728
L + +++ A L+ +++ + +++ +EE++ + + EK+ + K++E +K+ E
Sbjct: 331 LGKELQSVSAKLQAQVEE-NELWNRLNQQQEEKMWR--QEEKIQEWEEKIQEQEEKIREQ 387
Query: 729 VTKIL-RKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPV 787
KI ++ K ++EE + EK K ++ M ++K + E E +
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM----WEKEEKMRRQEEMMWEKEEKIREL 443
Query: 788 INNLI-QMILAEIESERDIPTVSTVQKDHKEKEKQ--RQEQYLQEGQE----QMSGMSLK 840
+ Q + E E +R Q+ +E+E + RQE+ ++E +E Q M +
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 841 QQLLGERNLLKEHYEKIS--ENW-------EEKKAWLQMK-----EGKQEQQSQKQW--- 883
++ + E+ ++E ++ E W E+++ W Q + E K +Q +K W
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQE 563
Query: 884 ------------QEEEMWKEEQK--QATPKQAEQEEK---QKQRGQEEEELPKSSLQRLE 926
QEE++W++E+K + K EQEEK Q++ QE+EE +++
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 927 EGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKD 986
E +KM+ Q + ++ ++R+ +K+ + R ++ +++ E+ E E+ + ++
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Query: 987 QMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLK 1034
+MQ +E + + E+ + W+ ++ Q+ + +E Q +L+
Sbjct: 684 KMQEQEEKMRRQEEKM----------WEQEVRLRQQEEKMQEHQEHLE 721
Score = 77.4 bits (189), Expect = 2e-13
Identities = 94/467 (20%), Positives = 212/467 (45%), Gaps = 40/467 (8%)
Query: 608 KKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSE-Q 666
KK I++GT +Q SHQ ++L R + + R+L K+E Q
Sbjct: 147 KKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQ--KTELQ 204
Query: 667 SNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVA 726
L Q A+ + D I + D E E A A + K K + Y +++
Sbjct: 205 MALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQ----KKKADRYIEELT 260
Query: 727 ETVTKI-LRKYKDTKKEEQVGEKPIKQKKVVSFMPG----LHFQKSPISAKSESSTLL-- 779
+ + L Y++T +E++ EK K ++ + + + + K E + LL
Sbjct: 261 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 320
Query: 780 --SYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGM 837
++ + +Q + A+++++ + + +E++ RQE+ +QE +E++
Sbjct: 321 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 380
Query: 838 SLKQQLLGERNLLKEHYEKISEN----WEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQ 893
++++ + ++E EK+ WE+++ + +E E++ + + QEE MW++E+
Sbjct: 381 --EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 894 K--------QATPKQAEQEEK----QKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEK 941
K K EQEEK +K R QE+ + ++ + R EE ++ + + + E+
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK--IREQ 496
Query: 942 ENGQMRQIQK--EAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELE 999
E RQ +K E + + +R++ +E + E + + E + K+++ +E + ++ E
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Query: 1000 KMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPI 1046
+ + + + + + + + ++ + +E R + E + +++E I
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE--EKIREQEEKI 601
Score = 73.9 bits (180), Expect = 2e-12
Identities = 111/498 (22%), Positives = 217/498 (43%), Gaps = 39/498 (7%)
Query: 442 KKGDFYQEDETDEYQSWKRSHKKATYV-YETSGPNLSDNKSGQKVSEAKPSQYYELQVLK 500
KK D Y E+ T E + + T E N + Q V K ++ LK
Sbjct: 250 KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELK 309
Query: 501 KKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRP 560
+K + K + +A+ HL E +S K + E + ++ ++ +++
Sbjct: 310 RKLERAKLLLPQQQ---LQAEADHLG-KELQSVSAKLQAQVEENELWNRLNQQQ--EEKM 363
Query: 561 TAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSK 620
E K++ E + +E + +IR E + Q+ K++ ++ + K
Sbjct: 364 WRQEEKIQEWEEKI-QEQEEKIREQEEKI---------REQEEKMRRQEE-----MMWEK 408
Query: 621 EEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFL 680
EEK +EE+ + + ++ + E E R LE + EQ + E +E
Sbjct: 409 EEKMRRQEEMMWE--KEEKMRRQEEMMWEKEEKIRELE--EKMHEQEKIREQEEKRQE-- 462
Query: 681 KQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTK 740
++KI K +++ +E R + EK+ + KM +K+ E KI + K +
Sbjct: 463 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ-EKIREEEKRQE 521
Query: 741 KEE--QVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPV--INNLIQMIL 796
+EE + EK +Q+++ +H Q+ I + E + D I + +
Sbjct: 522 QEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581
Query: 797 AEIESERDIPTVSTVQKDH-KEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYE 855
+ E R+ Q++ +E+E+ QEQ + G+++ ++++ + ++ E
Sbjct: 582 RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 856 KISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEE 915
KI E +EKK + +E +EQ+ Q QEE+MW++E+K ++ QE+++K R QEE+
Sbjct: 642 KIRE--QEKKI-REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698
Query: 916 ELPKSSLQRLEEGTQKMK 933
+ RL + +KM+
Sbjct: 699 MWEQE--VRLRQQEEKMQ 714
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 89.7 bits (221), Expect = 3e-17
Identities = 118/636 (18%), Positives = 279/636 (43%), Gaps = 62/636 (9%)
Query: 412 ERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQ----SWKRSHKKATY 467
ER EL + + +E++ K N L++ E E E Q KR ++A +
Sbjct: 205 ERDALSLELYRNTITNEELK----KKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKF 260
Query: 468 VYETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSL 527
+ N + ++ E + Q K +++E K + +++ E K +
Sbjct: 261 LLPQVQTNTLQEEMWRQEEELRE------QEKKIRKQEEKMWRQEERLREQEGKMREQEE 314
Query: 528 TETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVE 587
+ + + EQ ++++ + ++ + + E E +K + E + +
Sbjct: 315 KMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ 374
Query: 588 PLSMIQFDDTAEPQKGKIKGKKHHI--SSGTITSKEEKTEEKEELTKQVKSHQLVKSLSR 645
+ + + Q+ K++ ++ + + KEE+ E+E++ +QV+ + K +
Sbjct: 375 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Query: 646 VAKETSESTRVLESPDG--------KSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVP 697
K+T + ++ + + E+ + E +E + + + K + ++ +P
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 698 KEEELLKRAEAEKLGIIKAKMEEYFQKVAETVT------KILRKYKDTKKEEQVGEKPIK 751
+++E K E EK+ + K+ E +K+ + K+ R+ K ++E+Q+ E+ K
Sbjct: 495 EQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 752 QKKVVSFMPGLHFQKSPISAKSESSTLLSYEST--DPVINNLIQMILAEIESERDIPTVS 809
+ M + + + E T E + + + + E E R+
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 612
Query: 810 TVQKDHKEKEKQR---QEQYLQEGQEQM----SGMSLKQQLLGERNLLKEHYEKISENW- 861
Q++ ++++++ QE+ +QE +E+M M +++ + E+ L E EK+ E+
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672
Query: 862 ---------EEKKAWLQMK-EGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEE----KQ 907
+E+K W Q K E K ++Q +K W +E+M +EE + K+ +EE +Q
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732
Query: 908 KQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKE 967
+++ QE+EE + + + E +KM Q E++ + +++ ++ + L H + ++ ++
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQ----EEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
Query: 968 KQKPERGLEDLERQIKTKDQMQ--MKETQPKELEKM 1001
+ E + D E +++ +++ +E + EKM
Sbjct: 789 IWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Score = 88.6 bits (218), Expect = 7e-17
Identities = 145/738 (19%), Positives = 324/738 (43%), Gaps = 80/738 (10%)
Query: 290 YAHETSEAEKELSLKIIR------DLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAK 343
Y E ++ LSL++ R +L +N LQ+KL AE + ++ ++ +++L K
Sbjct: 198 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEI---QLNVKELKRK 254
Query: 344 LSTSSTLKVLPGPSPQSSRAIIKVGDTEDNM---DNILDKELENIVDEVQRKETKDSGIK 400
L + L P Q++ ++ E+ + + + K+ E + + +R ++ ++
Sbjct: 255 LERAKFLL----PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR 310
Query: 401 WDSTISYTAQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKR 460
+ + ELR+Q + E ++ ++ + E E + ++
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Query: 461 SHKKATYVYETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEA 520
++ ++E + + E Q L+ +++ +E + E K E
Sbjct: 371 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK 430
Query: 521 KRKHLSLTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESL--DKEG 578
K + +T+ Q K + E+ +K++ E ++ E K++ E++ +E
Sbjct: 431 KMQEQE-KKTRDQEEKMQEEERIREREKKMREE---EETMREQEEKMQKQEENMWEQEEK 486
Query: 579 KGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQ 638
+ + + L E + + + Q+ KI +EEK ++EE+ Q K
Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQEQEEKI------------WEQEEKIRDQEEMWGQEKK-- 532
Query: 639 LVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPK 698
+ R K + ++ E + +Q QE M Q+ + K +D++ +
Sbjct: 533 ----MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK--KTWDQEEKMR 586
Query: 699 EEELLK------RAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQ 752
EEE ++ R E E + + KM+E +K+ E K+ ++ +K ++ EK +Q
Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM---WEQEEKMQEQEEKMWEQ 643
Query: 753 KKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQ 812
++ + +++ + + E L +E +Q E E I ++
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEK--LWEHEK--------MQEQEKMQEQEEKIWEQEKME 693
Query: 813 KDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKE 872
K +E+EK+ +Q ++ +E+ S ++++ E +++E EK+ E EEK +Q +E
Sbjct: 694 KKTQEQEKKTWDQ--EKMREEESMREREKKMREEEEMMREQEEKMQEQ-EEK---MQEQE 747
Query: 873 GKQEQQSQKQW-QEEEMWKE----EQKQAT---PKQAEQEE--KQKQRGQEEEELPKSSL 922
+ +Q +K W QEE+MW++ EQK+ K EQE+ +Q+++ +++EE +
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 923 QRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQI 982
+++ +KM+ Q EK GQ ++ + + + + G+E++ E+ E+
Sbjct: 808 EKMRGQEEKMRGQE---EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMR 864
Query: 983 KTKDQMQMKETQPKELEK 1000
+ +++M+ +E + +E E+
Sbjct: 865 EQEEKMRGQEEKMREQEE 882
Score = 73.9 bits (180), Expect = 2e-12
Identities = 132/627 (21%), Positives = 275/627 (43%), Gaps = 64/627 (10%)
Query: 442 KKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLSDNKSGQKVSEAKPSQYYELQVLKK 501
KK D Y E+ T E + + T E ++ + ++E++ S+ +L V +
Sbjct: 193 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEI-QLNVKEL 251
Query: 502 KRK-EMKSFSEDKSKSPT---EAKRKHLSLTETKSQGGKSGTSMMMLEQFRKVKRESPFD 557
KRK E F + ++ T E R+ L E + + K M E+ +++ +
Sbjct: 252 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE--RLREQEGKM 309
Query: 558 KRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTI 617
+ + E +KE + + + L E + + ++ + Q+ K+ ++ +
Sbjct: 310 REQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMRE--- 366
Query: 618 TSKEEKTEEKEELTKQVKSHQLVKSLSRVAKET--SESTRVLESPDGKSEQSNLEEFQEA 675
+E+ ++E L +Q K + + R +E + R+ E + EQ + E E
Sbjct: 367 -QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVE- 424
Query: 676 IMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRK 735
K + + + +KKT +EE K E E++ + KM E + + E K+ ++
Sbjct: 425 -----KMREEKKMQEQEKKTRDQEE---KMQEEERIREREKKMREEEETMREQEEKMQKQ 476
Query: 736 YKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMI 795
++ ++E EK +Q+++ L Q+ K + +E + I + +M
Sbjct: 477 EENMWEQE---EKEWQQQRLPEQKEKLWEQE-----KMQEQEEKIWEQEEK-IRDQEEMW 527
Query: 796 LAEIESERDIPTVSTVQKDHKEKEKQR-QEQYLQEGQEQMSGMSLKQQLLGERNLLKEHY 854
E + R + +++EK R QEQ + + +E+M + +Q+ ++ +E
Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE---KKTWDQEEK 584
Query: 855 EKISENWEEKKAWLQMKEGKQEQQSQKQW--------QEEEMWKEEQK--QATPKQAEQE 904
+ E E++ ++ +E +Q +K QEE+MW++E+K + K EQE
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 905 EK---QKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRR 961
EK Q+++ E++ LP+ + E +KM+ Q + E+E Q +K K +
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEH--EKMQEQEKMQEQEEKIWEQ-EKMEKKTQEQEK 701
Query: 962 REKGKEKQKPERGLEDLERQIKTKDQM--QMKETQPKELEKMVIQTPMTLSPRWKSVLKD 1019
+ +EK + E + + E++++ +++M + +E ++ EKM Q W+ K
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE----EEMWEQEEKM 757
Query: 1020 VQRSYEGKEFQRNLKTLENLPDEKEPI 1046
++ + E QR LP++KE +
Sbjct: 758 WEQEEKMWEQQR-------LPEQKEKL 777
Score = 35.4 bits (80), Expect = 0.67
Identities = 70/377 (18%), Positives = 161/377 (42%), Gaps = 32/377 (8%)
Query: 483 QKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMM 542
+K+ E + + + + ++ + ++M E K E ++K T Q K
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK------TWDQEEKMREEER 590
Query: 543 MLEQFRKVKRESPF----DKRPTAAEIKVEPTTESL----DKEGKGEIRSLVEPLSMIQF 594
M E+ +K++ E +++ E K++ E + +K + E + + M +
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 595 DDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSEST 654
++ Q+ ++ +K + ++EK +E+EE K + ++ K K+T +
Sbjct: 651 EEKMWEQQ-RLPEQKEKLWEHEKMQEQEKMQEQEE--KIWEQEKMEKKTQEQEKKTWDQE 707
Query: 655 RVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGII 714
++ E + + + E +E +M ++K+ ++K +EEE+ + + EK+
Sbjct: 708 KMREEESMREREKKMRE-EEEMMREQEEKMQEQ----EEKMQEQEEEMWE--QEEKMWEQ 760
Query: 715 KAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSE 774
+ KM E Q++ E K L +++ +++E++ E+ K + M G + K
Sbjct: 761 EEKMWEQ-QRLPEQKEK-LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR 818
Query: 775 SSTLLSYESTDPVINNLIQMILAEI-----ESERDIPTVSTVQKDHKEKEKQR-QEQYLQ 828
+ + + +M E E + + +K +++EK R QE+ ++
Sbjct: 819 GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMR 878
Query: 829 EGQEQMSGMSLKQQLLG 845
E +E+M G K +G
Sbjct: 879 EQEEKMRGQEEKIYCVG 895
>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
Length = 1700
Score = 89.0 bits (219), Expect = 5e-17
Identities = 174/801 (21%), Positives = 294/801 (36%), Gaps = 134/801 (16%)
Query: 955 HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006
HLGP E P+ E+L + T D + +P++ +K+ Q
Sbjct: 86 HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQER 142
Query: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISG 1066
+ +SP K + KD + + E + L +K+ + S PG+LP
Sbjct: 143 LPVSP--KKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQ-NEYSSTDTPYPGSLP--- 196
Query: 1067 QPLTKCIHLTPQQAQEVGITLTPQQAQAQGI-TLTLQQAQELGIPLTPQQAQALEILFTP 1125
L P +++VG + + + Q TL Q+ L Q Q LE +
Sbjct: 197 PELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS 256
Query: 1126 QQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------------- 1159
Q +A P P ++ ++ +TL P +DQA P I++
Sbjct: 257 MQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 1160 ----TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQAL 1203
++Q Q+ I P QQ + P+ P + EL I P+ P ++
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPR- 371
Query: 1204 RVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQEL 1263
V +P Q + G P P+ + Q L P + + +T+ + E+
Sbjct: 372 EVESSPTQQETPGQP--PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
Query: 1264 GIPLTPQQA----QALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPF---- 1315
G L Q+A G + P Q G PL P+ ++ G PL +Q + P
Sbjct: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQSPEPINN 488
Query: 1316 -TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMP 1374
P Q PQ A+ E +LT Q+A P T + + + P+H+ +
Sbjct: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSH---LT 540
Query: 1375 LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEIT 1434
T Q +LG +TP+ + + T ++ TP Q + +P T
Sbjct: 541 QATVQPLDLGFTITPESKTEVELSPTMKE--------TPTQPPKKVVPQLRVYQGVTNPT 592
Query: 1435 LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIP 1494
QAQ P Q +LG+T+TP+ E+G P++ ++ P+ E+ +P
Sbjct: 593 PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRT------IVSPKHPEVTLP 646
Query: 1495 LTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELGIP----- 1542
Q Q Q + Q +LG +TP + + AL PP E+ +P
Sbjct: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
Query: 1543 ------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1596
LT VQ L + L E+ +P + T Q +LG+ + P+
Sbjct: 707 QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGLAIIPEPT 760
Query: 1597 QELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNA 1656
E ++ A P + Q L SLT +T P + + + +
Sbjct: 761 TETRHSTALEKTTAP----RPDRVQTLHRSLTE-------VTGPPTELEPAQDSLVQSES 809
Query: 1657 WVSAVTLTSEQTHALESPMNL 1677
+ LT+ + H + N+
Sbjct: 810 YTQNKALTAPEEHKASTSTNI 830
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 87.8 bits (216), Expect = 1e-16
Identities = 113/517 (21%), Positives = 235/517 (45%), Gaps = 94/517 (18%)
Query: 576 KEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQ-- 633
K+ +GE R L+ L K G+ S T K++ EELTK+
Sbjct: 154 KQLEGEARDLISRLH----------DSWKFAGELEQALSAVATQKKKADRYIEELTKERD 203
Query: 634 -----------------VKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAI 676
K+ +L + L V E SE ++ K E++ L Q+ +
Sbjct: 204 ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQL 263
Query: 677 MAFLKQKIDNIGKAFDKKTVP-----KEEEL---LKRAEAEKLGIIKAKMEEYFQKVAET 728
A + D++GK + +E EL L + + EK+ + K++E+ +K+ E
Sbjct: 264 QA----EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 729 VTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVI 788
KI ++EE++ E+ K ++ M ++K + E + +E + +
Sbjct: 320 EEKI------REQEEKIREQEEKMRRQEEMM----WEKEEKMRRQEE---MMWEKEEKM- 365
Query: 789 NNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERN 848
L +M+ + E R++ Q+ +E+E++RQE+ ++ +EQ + ++ +
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE--EKIREQEKRQEQEAKMWRQEE 423
Query: 849 LLKEHYEKISENWEEKKAWLQ---------MKEGKQEQQSQKQW-------QEEEMWKEE 892
++E EKI E +EKK W Q ++E ++ Q+ ++ W ++EE+W+++
Sbjct: 424 KIREQEEKIRE--QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 481
Query: 893 QK----QATPKQAE----QEEK-----QKQRGQEE-----EELPKSSLQRLEEGTQKMKT 934
+K + KQ E QEEK +K R QEE EE + +++ E +K++
Sbjct: 482 EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
Query: 935 QGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQ 994
Q +++++ +M + Q+E RR++ K +++ E+ E E+ + ++++ +E +
Sbjct: 542 QEEMMQEQEEKMGE-QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
Query: 995 PKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQR 1031
+E E+M+ + + + + + + ++ E +E R
Sbjct: 601 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637
Score = 79.7 bits (195), Expect = 3e-14
Identities = 87/448 (19%), Positives = 214/448 (47%), Gaps = 44/448 (9%)
Query: 609 KHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSN 668
++ I+ + K K +EK +L + KS ++ ++ + ++ + +L ++E +
Sbjct: 211 RNTITDEELKEKNAKLQEKLQLVESEKS-EIQLNVKELKRKLERAKLLLPQQQLQAEADH 269
Query: 669 LEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEA-----EKLGIIKAKMEEYFQ 723
L + +++ A L+ +++ + +++ +EE++ ++ E EK+ + K+ E +
Sbjct: 270 LGKELQSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 724 KVAETVTKILRKY--------KDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSES 775
K+ E K+ R+ K ++EE + EK K +++ M + + K
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388
Query: 776 STLLSYESTDPVINNLIQMILAEIESE----RDIPTVSTVQKDHKEKEKQ--RQEQYL-- 827
+ + I+ E E R + ++ +E+EK+ RQE+ +
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 448
Query: 828 ------QEGQEQMSGMSLKQQLLGERNLLKEHYEKISENW----EEKKAWLQMKEGKQEQ 877
+E +++ M +++ + E+ + EK+ E +E+K W Q +E +Q
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ-EEKMHDQ 507
Query: 878 QSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGL 937
+ + + QEE+MW++E+K +Q E+ +Q+++ +E+EE+ + +++ E +KM+ Q
Sbjct: 508 EEKIREQEEKMWRQEEK--IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-- 563
Query: 938 LLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKE 997
EK Q +I+++ + + R +K K +++ E+ E E+ + ++ MQ +E + E
Sbjct: 564 --EKMRRQEEKIREQEEKI----REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
Query: 998 LEKMVIQTPMTLSPRWKSVLKDVQRSYE 1025
E+ + + + + + + + ++ +E
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKMWE 645
Score = 78.6 bits (192), Expect = 7e-14
Identities = 97/429 (22%), Positives = 188/429 (43%), Gaps = 52/429 (12%)
Query: 608 KKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSE-Q 666
KK I++GT +Q SHQ ++L R + + R+L K+E Q
Sbjct: 86 KKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQ--KTELQ 143
Query: 667 SNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVA 726
L Q A+ + D I + D E E A A + K K + Y +++
Sbjct: 144 MALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQ----KKKADRYIEELT 199
Query: 727 ETVTKI-LRKYKDTKKEEQVGEKPIKQKKVVSFMPG----LHFQKSPISAKSESSTLL-- 779
+ + L Y++T +E++ EK K ++ + + + + K E + LL
Sbjct: 200 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 259
Query: 780 --SYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGM 837
++ + +Q + A+++++ + + +E++ RQE+ +QE +E++
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 838 SLKQQLLGERNLLKEHYEKISENWEEKKAWLQM---KEGKQEQQSQKQWQEEE------- 887
K ++E EKI E E+ + +M KE K +Q + W++EE
Sbjct: 320 EEK---------IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE 370
Query: 888 -MWKEEQK--------QATPKQAEQEEK----QKQRGQEEEELPKSSLQRLEEGTQKMKT 934
MW++E+K K EQEEK +K R QE+ + ++ + R EE ++ +
Sbjct: 371 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 430
Query: 935 QGLLLEKENGQMRQIQK--EAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKE 992
+ + E+E RQ +K E + + +R++ +E + E + + E + K++M +E
Sbjct: 431 K--IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQE 488
Query: 993 TQPKELEKM 1001
K+ EK+
Sbjct: 489 KIRKQEEKV 497
Score = 77.4 bits (189), Expect = 2e-13
Identities = 116/504 (23%), Positives = 215/504 (42%), Gaps = 46/504 (9%)
Query: 442 KKGDFYQEDETDEYQSWKRSHKKATYV-YETSGPNLSDNKSGQKVSEAKPSQYYELQVLK 500
KK D Y E+ T E + + T E N + Q V K ++ LK
Sbjct: 189 KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELK 248
Query: 501 KKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRP 560
+K + K + +A+ HL E +S K + E + ++ ++ +++
Sbjct: 249 RKLERAKLLLPQQQ---LQAEADHLG-KELQSVSAKLQAQVEENELWNRLNQQQ--EEKM 302
Query: 561 TAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSK 620
E K++ E + +E + +IR E + Q+ K++ ++ + K
Sbjct: 303 WRQEEKIQEWEEKI-QEQEEKIREQEEKI---------REQEEKMRRQEE-----MMWEK 347
Query: 621 EEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFL 680
EEK +EE+ + + ++ L + E E R LE + EQ + E +E
Sbjct: 348 EEKMRRQEEMMWE--KEEKMRRLEEMMWEKEEKIRELE--EKMHEQEKIREQEEKRQE-- 401
Query: 681 KQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTK 740
++KI K +++ +E R + EK+ + KM +K+ E KI + K +
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ-EKIREEEKRQE 460
Query: 741 KEE--QVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAE 798
+EE + EK +Q+++ +H Q+ K E E + +
Sbjct: 461 QEEMWRQEEKIREQEEIWRQKEKMHEQEK--IRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
Query: 799 IESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQ----LLGERNLLKEHY 854
E I ++ +EK ++ QE+ +QE +E+M K Q + + ++E
Sbjct: 519 WRQEEKIREQEEKIREQEEKIRE-QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE 577
Query: 855 EKISENWE-----EKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQ 909
EKI E E E+K W + +E +EQ+ Q QEE+MW++E+K ++ QE+++K
Sbjct: 578 EKIREQKEKIREQEEKIW-EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636
Query: 910 RGQEEEELPKSSLQRLEEGTQKMK 933
R QEE+ + RL + +KM+
Sbjct: 637 RRQEEKMWEQE--VRLRQQEEKMQ 658
Score = 65.1 bits (157), Expect = 8e-10
Identities = 107/550 (19%), Positives = 239/550 (43%), Gaps = 54/550 (9%)
Query: 486 SEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLE 545
+E + + YY +K+ E + S A +L+ +Q K+ + L
Sbjct: 140 TELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELT 199
Query: 546 QFR-----KVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSM-IQFDDTAE 599
+ R ++ R + D+ K++ + ++ E K EI+ V+ L ++
Sbjct: 200 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE-KSEIQLNVKELKRKLERAKLLL 258
Query: 600 PQKGKIKGKKHHISSG--TITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVL 657
PQ+ +++ + H+ ++++K + E+ EL ++ Q K + K ++
Sbjct: 259 PQQ-QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 658 ESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAK 717
E + EQ QE M ++ + ++K+ + +E + + EK+ ++
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMM------WEKEEKMRRQEEMMWEKEEKMRRLEEM 371
Query: 718 MEEYFQKVAETVTKILRKYKDTKKEE--QVGEKPIKQKKVVSFMPGLHFQKSPISAKSES 775
M E +K+ E K+ + K ++EE Q EK +Q+K + Q+ I + E
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431
Query: 776 STLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQE--- 832
I + + + E + + +K +++E RQE+ ++E +E
Sbjct: 432 ------------IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 833 QMSGMSLKQQLLGERNLLKEHYEKISENWE-----EKKAWLQ------MKEGKQEQQSQK 881
Q M ++++ + + EK+ + E E+K W Q +E +EQ+ +
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539
Query: 882 QWQEEEMWKEEQKQATPKQAEQEE----KQKQRGQEEEELPKSSLQRLEEGTQKMKTQGL 937
+ QEE M ++E+K ++ QE+ +Q+++ +E+EE + +++ E +K+ Q
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 938 LLEKENGQMRQIQKEAKHLGPHR---RREKGKEKQKPERGLED--LERQIKTKDQMQMKE 992
+ +E +M Q Q+E + + EK +E+++ R E+ E++++ + Q + +
Sbjct: 600 KI-REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Query: 993 TQPKELEKMV 1002
+ LE +
Sbjct: 659 EHQEHLEAAI 668
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 87.8 bits (216), Expect = 1e-16
Identities = 183/733 (24%), Positives = 247/733 (33%), Gaps = 116/733 (15%)
Query: 1242 PLTPQQAQALGI-TLTPKQVQELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLG 1300
P P Q + G+ L P QV P A ALG P + L P +P +
Sbjct: 266 PAHPSQPKPKGLQALRPPQVT----PPRKDAAPALG----PLSSSPLATP-SPSGTKARP 316
Query: 1301 IPLTPKQAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELG 1360
+P A L P A +PL P P Q L P T +Q
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA------PPSLQTLPSPPATPPSQAPP 370
Query: 1361 IPLTPQHAQALGMPLTTQQAQELGIP--LTPQQAQALGMPLTTQQAQ---ELGIPLTPQQ 1415
TP + P + Q + +P LT QA PL Q LG P Q
Sbjct: 371 SMTTPP----MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL--Q 424
Query: 1416 AQELGIPFTPQQAQAQEIT-----LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIP 1470
A + +P+Q QA + TP + L PL+ + L +L+P L P
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSP 483
Query: 1471 LTPQQAQALG-IPLIPPQAQELGIPLTPQQAQALGILLIPPQAQELGIPLTPQQAQALGI 1529
LT QAL + PQA + + P + Q+ L PP Q LT + L
Sbjct: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS---LAPPSLQTPPASLTTPPLENLP- 539
Query: 1530 PLIPPQAQELGIPLTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGI 1589
L PP Q PLT ++ P P Q PLT TP I
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPLT-----------TPPPETPSSI 587
Query: 1590 PLTPQQAQELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGV 1649
P QA P QG+P P A TP + L P QA
Sbjct: 588 ATPPPQA-----PPALASPPLQGLPSPPLSPLA-----TPPPQAPPXLALPPLQAP---- 633
Query: 1650 PITPVNAWVSAVTLTSEQT------HALESPMNLEQAQEQLLKLGVPLTLDKAHTLGSPL 1703
P P + +S + S Q H L++P + + P SP
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP---------ASPP 684
Query: 1704 TLKQVQWSHRPFQKSKASLPTGQSIISRLSPSLRLSLASSAPTAEKSSIFGVSSTPLQIS 1763
S ++ P Q+ S +P L++ + A S P ++
Sbjct: 685 V-------------SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 1764 RVPLNQGPFAPGKPLEMGILSEPGKLGAPQTLRSSGQTLVYGGQSTSAQFPAPQAPPSP- 1822
PL P P P + P ++ P L + P Q PPSP
Sbjct: 732 APPLQVPPSPPASPPMSPSATPPPRV--PPLLAA----------------PPLQVPPSPP 773
Query: 1823 GQLPISR-APPTPGQPFIAGVPPTSGQIPSLWAPLSPGQPLVPEASSIPGDLLESGPLTF 1881
LP+S A P P P PP +PS A PGQ ++S+P L + P
Sbjct: 774 ASLPMSPLAKPPPQAPPALATPPLQA-LPSPPASF-PGQAPFSPSASLPMSPLATPPPQA 831
Query: 1882 SEQLQE--FQPPATAEQSPYLQAPSTPGQHLATWTLPGRASSLWIPPTSRHPPTLWPSPA 1939
L Q P + SP LQAP P ++ G +L + P PP+ PS
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
Query: 1940 PGKPQKSWSPSVA 1952
P + S A
Sbjct: 892 LSGPDLAGHSSSA 904
Score = 81.6 bits (200), Expect = 8e-15
Identities = 168/691 (24%), Positives = 240/691 (34%), Gaps = 94/691 (13%)
Query: 1334 TQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLT--TQQAQELGIPLTPQQ 1391
T E + ++ + G L ++ L TP + A P T +A P+
Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 276
Query: 1392 AQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQAQALGMPLTAQQ 1451
QAL P T ++ L P + L P +P +A +P
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATP-------------SPSGTKARPVPPPDNA 323
Query: 1452 AQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQAQALGILLIPPQ 1511
A L TL P +PL P P PP Q L P +QA + PP
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPS------PSAPPSLQTLPSPPATPPSQAPPSMTTPP- 376
Query: 1512 AQELGIPLTPQQAQALGIP--LIPPQAQELGIPLTPQQVQA---LGIPLIPPQAQELEIP 1566
+ P + Q + +P L P Q PL +QA LG P + QA +
Sbjct: 377 ---MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL--QATHSFLT 431
Query: 1567 LTPQQAQA-LGIPL----TPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQAQ 1621
++P+Q QA L P TP + L PL+ + L L+P + PLT Q
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS-PLTIHPLQ 490
Query: 1622 ALG-ISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVTLTSEQTHALESPMNLEQA 1680
AL ++ QA + + P + Q+ P + S T E +L P
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPP------ 544
Query: 1681 QEQLLKLGVPLTLDKAHTLGSPLTLKQVQWSHRPFQKSKASLPTGQSIISRLSPSLRLSL 1740
PL T +PLT ++ P + L S ++ P S+
Sbjct: 545 ---------PL-----QTASAPLTTPHLETPPCP---APCPLQAPPSPLTTPPPETPSSI 587
Query: 1741 ASSAPTAEKS----SIFGVSSTPLQISRVPLNQGP--------FAPGKPLEMGILSEPGK 1788
A+ P A + + G+ S PL P Q P AP P LS P
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS-PLA 646
Query: 1789 LGAPQTLRSSGQTLVYGGQSTSAQFP--APQAPPSPGQLPISRAPPTPGQPFIAGVPPTS 1846
+PQ + L+ S P AP +PP+ + S PP+ P +A P
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 1847 GQIPSLWAPLSPG--------QPLVPEASSIPGDLLESGPLTFSEQLQEFQPPATAEQSP 1898
P P+SP PL +P S P++ S PP A +P
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA--AP 764
Query: 1899 YLQAPSTPGQHLATWTL----PGRASSLWIPPTSR--HPPTLWPSPAPGKPQKSWSPS-V 1951
LQ P +P L L P +L PP PP +P AP P S S +
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Query: 1952 AKKRLAIISSLKSKSVLIHPSAPDFKVAQVP 1982
A L + + + PS P Q P
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855
Score = 78.6 bits (192), Expect = 7e-14
Identities = 198/816 (24%), Positives = 271/816 (33%), Gaps = 95/816 (11%)
Query: 1173 PQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQAQALGITLT 1232
P+ QAL P ++ L P + L TP + P+ P A + T
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSGTKARPVPPPDNAATPLPAT 330
Query: 1233 LQQAQQLG--IPLTPQQAQALGITLTPKQVQEL-GIPLTPQQAQALGITLTPKQAQELGI 1289
L + L +PL P A P +Q L P TP +T P QA
Sbjct: 331 LPPSPPLATPLPLAPPSPSA------PPSLQTLPSPPATPPSQAPPSMTTPPMQA----- 379
Query: 1290 PLNPQQAQTLGIP--LTPKQAQALGIPFTPQQAQA---LGIPLTPQQAQTQEITLTPQQA 1344
P + Q + +P LT QA P QA LG P QA +T++P+Q
Sbjct: 380 PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL--QATHSFLTMSPRQT 437
Query: 1345 QALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQAQELGIPLTPQQAQALGMPLTTQQA 1404
QA LT+ TP + L PL+ + L L+P L PLT
Sbjct: 438 QA---SLTSPSRPAS----TPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPL 489
Query: 1405 QELG-IPLTPQQAQELGIPFTPQQAQAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQ 1463
Q L + QA + P + Q+ +L P Q LT + L +L P
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQS---SLAPPSLQTPPASLTTPPLENLP-SLAPPP 545
Query: 1464 AQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQQAQALGILLIPPQAQEL-------G 1516
Q PLT + P P TP I PPQA G
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605
Query: 1517 IPLTPQQAQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQAQELEIPLTPQQAQALG 1576
+P P A P PP L +P +QA P P L P +PQ AL
Sbjct: 606 LPSPPLSPLATPPPQAPPX---LALP----PLQAPPSPPASPPLSPLATP-SPQAPNALA 657
Query: 1577 IPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQG 1636
+ L L P +P + + P +P + TP ++ P Q
Sbjct: 658 VHL-------LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 1637 ITLTPQQAQALGVPITPVNAWVSAVTLT-SEQTHALESPMNLEQAQEQLLKLGVPLTLDK 1695
P A P P + + S SP + L PL +
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 1696 AHTLGSPLTLKQVQWSHRPFQKSKA-SLPTGQSIISRLSPSLRLSLASSAPTAEKSSIFG 1754
+ P +L + P Q A + P Q++ PS S AP + +S+
Sbjct: 771 S----PPASLPMSPLAKPPPQAPPALATPPLQAL-----PSPPASFPGQAPFSPSASL-- 819
Query: 1755 VSSTPLQISRVPLNQGPFAPGKPLEMGILSEPGK--LGAPQTLRSSG-QTLVYGGQSTSA 1811
P+ P Q P PL S P L AP+ + G T V G + T A
Sbjct: 820 ----PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 875
Query: 1812 QFPAPQAPPSPGQLPISRAPPTPGQPFIAGVPPTSGQIPSLWAPLSPGQPLVPEASSIP- 1870
P P PP P + P S T P +AG ++ P G AS P
Sbjct: 876 LAPGP--PPPPSRSPSS----TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 929
Query: 1871 GDLLESGPLTFSEQLQEFQPPATAEQSPYLQAPSTPGQHLATWTLPGRASSLWIPPTSRH 1930
+L P +S + PP +P P P T PG A L +
Sbjct: 930 AELAACHPAAWS---RGPAPPLAFRGAPGAPLPWPPA------TGPGSADGLCTIYETEG 980
Query: 1931 PPTLWPSPAPGKPQKSWSPSVAKKRLAIISSLKSKS 1966
P + P+P P S S K + S+S
Sbjct: 981 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 1016
Score = 45.8 bits (107), Expect = 5e-04
Identities = 107/454 (23%), Positives = 148/454 (32%), Gaps = 44/454 (9%)
Query: 1031 RNLKTLENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQQAQEVGITLTPQ 1090
R T + P + P+S+ P LQ SL A+ PLT IH P QA + +PQ
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT--IH--PLQALSSLASHSPQ 501
Query: 1091 QAQAQGITLTLQQAQELGIP--------LTPQQAQALEILFTPQQAQALGIPLTPQQTQV 1142
+ I L+ L P LT + L L P Q PLT +
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL-APPPLQTASAPLTTPHLET 560
Query: 1143 QGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQA 1202
P QAP LTT + TP + P Q G+P P A
Sbjct: 561 PPCP-APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ----GLPSPPLSPLA 615
Query: 1203 LRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITL-----TP 1257
+ PQ L +P QA L P +PQ AL + L +P
Sbjct: 616 ---TPPPQAPPXLALP----PLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSP 667
Query: 1258 KQVQELGIPLTPQQAQALGITLTPKQAQELGI---PLNPQQAQTLGIPLTPKQAQALGIP 1314
+ P +P + + + TP + PL + P++P P
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 1315 FTPQQAQALGIPLTPQQAQTQEITLTPQ---QAQALGMPLTTQQAQELGIPLTPQHAQAL 1371
P A L +P +P + + TP PL + +P++P
Sbjct: 728 -PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 1372 GMP--LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPF--TPQQ 1427
P L T Q L P QA P + L P PQ L P P
Sbjct: 787 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP-PPQAPPVLAAPLLQVPPS 845
Query: 1428 AQAQEITLTPQQAQALGMPLTAQQAQELGITLTP 1461
A P++ G P T+ L + L P
Sbjct: 846 PPASPTLQAPRRPPTPG-PDTSVSGPRLTLALAP 878
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 87.8 bits (216), Expect = 1e-16
Identities = 227/1119 (20%), Positives = 464/1119 (41%), Gaps = 138/1119 (12%)
Query: 14 ESEKCIKDSTIMRREPQNILSPLMLPNLEIPFSVKDIISRIERAQLHRAREDIDMQLSEI 73
E+E+ ++ + +E Q S L E+ + +++ + Q R + QL E
Sbjct: 839 ENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQ---ERLNEMEQLKEQ 895
Query: 74 MNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYAKTIEIREKTLANILAW 133
+ N R T T+ ER +L K +Q LE++ T + + ++ ++
Sbjct: 896 LEN--RDSTLQTV------EREKTLITEKLQQT---LEEVKTLTQEKDDLKQLQESLQIE 944
Query: 134 LEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKILSRFSTSFLDEKKKQKKK 193
++ + + M++D E L + L++++ + + ++ + +E +
Sbjct: 945 RDQLKSDIHDTVNMNIDTQ-------EQLRNALESLKQHQETINTLKSKISEEVSRNLHM 997
Query: 194 ILSRGTLWKSWKERVI----------KRPSTARALRPDQMISDQ----LATNTKVSEIQG 239
+ G ++++++ K T A D I +Q + + +E+Q
Sbjct: 998 EENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQ 1057
Query: 240 MLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETSEA-- 297
ML+ +I L+ + + I TI N L +L DELK + + A E + A
Sbjct: 1058 MLESVIAEK--EQLKTDLKENIEMTIEN-QEELRLLGDELK----KQQEIVAQEKNHAIK 1110
Query: 298 -EKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLK----- 351
E ELS R L+ E L++K Q +EK +QL+ + + ++ K++ LK
Sbjct: 1111 KEGELSRTCDR-LAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKN 1169
Query: 352 ---VLPGPSPQSSRAIIKVGDTEDNMDNI---------LDKELENIVDEVQR--KETKDS 397
L + K+ + + + +I L K E D ++ +E + +
Sbjct: 1170 KELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEAT 1229
Query: 398 GI--KWDSTISYTAQAERTPDLTELRQ-------QPVASEDISEDSTKDNVSLKKGDFYQ 448
G+ K + I++ E + ELR+ Q + ++D+ + TK + Q
Sbjct: 1230 GLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQ 1289
Query: 449 E--------DETDEYQSW------KRSHKKATYVYETSGPNLSDNKSGQKVSEAKPSQYY 494
E ET E + + + K +T + L N+ Q+ E
Sbjct: 1290 ELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQE------- 1342
Query: 495 ELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGT--SMMMLE---QFRK 549
E++ L K+R +K+ E + K +H+ T K Q +S S+ M E + K
Sbjct: 1343 EIKSLTKERDNLKTIKEALEVKHDQLK-EHIRETLAKIQESQSKQEQSLNMKEKDNETTK 1401
Query: 550 VKRESPFDKRPTAAEIKVEPTTESLDK---EGKGEIRSLVEPLSMIQ-FDDTAEPQKGKI 605
+ E K +A +++E L K E E++S+ + +Q + + + ++
Sbjct: 1402 IVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQL 1461
Query: 606 KGKKHHISSGTITSKEEKTEEKEELTKQVKS-HQLVKSLSRVAKETSESTRVLESPDGKS 664
K I + + ++EE L +Q ++ ++L +LS E S + LE+ + K
Sbjct: 1462 KENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKL 1521
Query: 665 EQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQK 724
Q+ ++E E F I I + +K K+ + ++A+ L I++KM E +
Sbjct: 1522 -QNKIQEIYEKEEQF---NIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNR 1577
Query: 725 VAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYEST 784
+ E+ +I K+ ++ ++V Q+ + L I AK + S Y+
Sbjct: 1578 LQESQEEIQIMIKEKEEMKRV------QEALQIERDQLKENTKEIVAKMKESQEKEYQFL 1631
Query: 785 DPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGM------- 837
N Q + EIE ++ + ++ E E R Q L E E+M +
Sbjct: 1632 KMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDL 1691
Query: 838 -SLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQA 896
S+++ L ER+ LKE+ + EK+ L++ ++ + + + E+ +
Sbjct: 1692 RSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEI 1751
Query: 897 TPKQAEQE------EKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQ 950
+ Q + E + Q + QEE + L+ +E K++ G++ EK + ++ +Q
Sbjct: 1752 SNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLR--GIVSEKTD-KLSNMQ 1808
Query: 951 KEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLS 1010
K+ ++ + +EK +E + E L L++ + ++ Q K ++ ++L+K + +TLS
Sbjct: 1809 KDLENSNA-KLQEKIQELKANEHQLITLKKDV---NETQKKVSEMEQLKKQIKDQSLTLS 1864
Query: 1011 PRWKSVLKDVQRSYEG-KEFQRNLKTLENLPDEKEPISI 1048
L Q+ +E +E + +K +NL +E + +
Sbjct: 1865 KLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKL 1903
Score = 84.3 bits (207), Expect = 1e-15
Identities = 216/1078 (20%), Positives = 452/1078 (41%), Gaps = 148/1078 (13%)
Query: 19 IKDSTIMRREPQNILSPLMLPNLEIPFSVKDIISRIERAQLHRAREDIDMQLSEIMNNVH 78
+K + + ++ +N LS + E +K + I+ +L + D+ L I +
Sbjct: 563 VKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQ 622
Query: 79 RIMTRY---TLVFNSSSE------RNVSLTEHKKKQRTNFLEK---MATYAKTIEIREKT 126
T + T+ ++ E N+ L E K+ T + + + Y +E ++K
Sbjct: 623 MKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKM 682
Query: 127 LANILAWLEE-WNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKILSRFSTSFLD 185
++ L+ +N++ +L+D + +EL E + L + ++
Sbjct: 683 QVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLEL--------EGKITDLQKELNKEVE 734
Query: 186 EKKKQKKKILSRGTLWK--SWKERVIKR-PSTARALRPDQMISDQLATNT--KVSEIQGM 240
E + +++++ L S ER+ K + L D+L + K S +QG+
Sbjct: 735 ENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGL 794
Query: 241 LQELIGTTM--FSTLENNAIKYISSTIVNLSTALSMLNDELKCV---NFQSSTVYAHETS 295
L+E IG T +T ++N K N T + K V N + + + +
Sbjct: 795 LEE-IGKTKDDLATTQSN-YKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSK 852
Query: 296 EAEK-ELSLKIIR-DLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVL 353
EA+K + SL ++ +LS + + LQ+K ++ +E+ ++ + K +E + L T K L
Sbjct: 853 EAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTL 912
Query: 354 PGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAER 413
Q + +K E + L + L+ ++R + K S I ++ Q +
Sbjct: 913 ITEKLQQTLEEVKTLTQEKDDLKQLQESLQ-----IERDQLK-SDIHDTVNMNIDTQEQL 966
Query: 414 TPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDET----DEYQSWKRSHKKATYVY 469
L L+Q E I+ +K + + + + + E+ T DE+Q K +
Sbjct: 967 RNALESLKQH---QETINTLKSKISEEVSR-NLHMEENTGETKDEFQQKMVGIDKKQDLE 1022
Query: 470 ETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLT- 528
+ L+ + ++ E + + +Q + ++ ++S +K + T+ K +++ +T
Sbjct: 1023 AKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLK-ENIEMTI 1081
Query: 529 ----ETKSQGG--KSGTSMMMLEQFRKVKRESPFDK---RPTAAEIKVEPTTESLDKEGK 579
E + G K ++ E+ +K+E + R E K++ ++ L +E +
Sbjct: 1082 ENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQL-QEKQ 1140
Query: 580 GEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQL 639
++ ++ E +S +Q + +I+ K+ + + +T + +TE E K ++++
Sbjct: 1141 QQLLNVQEEMSEMQ------KKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEE 1194
Query: 640 VKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKE 699
VKS+++ K E + E+ E+ +L + I A T +
Sbjct: 1195 VKSITKERKVLKELQKSFET-----ERDHLRGYIREIEA----------------TGLQT 1233
Query: 700 EELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFM 759
+E LK A L + ++E + V+E +I+ K ++ E+ +
Sbjct: 1234 KEELKIAHIH-LKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEE----------I 1282
Query: 760 PGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDH---K 816
P LH ++ + E S T +N L +L E + +D T++ ++ +
Sbjct: 1283 PVLHEEQELLPNVKEVS------ETQETMNEL--ELLTEQSTTKDSTTLARIEMERLRLN 1334
Query: 817 EKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYE----KISENWEEKKAWLQMKE 872
EK ++ QE+ +E+ + ++K+ L + + LKEH KI E+ +++ L MKE
Sbjct: 1335 EKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKE 1394
Query: 873 GKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEEL-----PKSSLQRLEE 927
++ ++ K E E +K + + E K+ + +E+ K LQRL+E
Sbjct: 1395 --KDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQE 1452
Query: 928 GTQKMKTQGLLLEKENGQMRQIQKE--AKHLGPHRRREKGKEKQKPERGLEDLERQI-KT 984
+L+ E+ Q+++ KE AKHL E +E + L++ E I +
Sbjct: 1453 ----------VLQSESDQLKENIKEIVAKHL------ETEEELKVAHCCLKEQEETINEL 1496
Query: 985 KDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDE 1042
+ + KET+ ++K + L + +Q YE KE Q N+K + + ++
Sbjct: 1497 RVNLSEKETEISTIQKQLEAINDKLQNK-------IQEIYE-KEEQFNIKQISEVQEK 1546
Score = 73.2 bits (178), Expect = 3e-12
Identities = 189/1063 (17%), Positives = 444/1063 (41%), Gaps = 143/1063 (13%)
Query: 4 KMKNEIDNDPESEKCIKDSTIMRREPQNILSPLMLPNLEIPFSVKDIISRIERA--QLHR 61
K K ++D + E + + T + + +L NLE+ + D+ + + +
Sbjct: 679 KKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEA 738
Query: 62 AREDIDM--QLSEIMNNVHRIM------TRYTLVFNSSSERNVSLTEHKKKQRTNFLEKM 113
RE++ + +L + + V R+ + + S ++ S HK+ + LE++
Sbjct: 739 LREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEI 798
Query: 114 ATYAKTIEIREKTLANILAWLEEWNDV------LSEMTLMDVDEHHHWIAQMELLPDTLK 167
KT + T +N + +E+ + + M ++E+ ++ L +
Sbjct: 799 G---KTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQ 855
Query: 168 AIENNVKILSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQ 227
++++ L + E +++ +++ R + KE++ R ST + + ++ + +
Sbjct: 856 KFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITE 915
Query: 228 LATNTKVSEIQGMLQELIGTTMFST---LENNAIKYISSTIVNLS--------TALSMLN 276
T + E++ + QE +E + +K VN++ AL L
Sbjct: 916 KLQQT-LEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLK 974
Query: 277 DELKCVNFQSSTVYAHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKI- 335
+ +N S + + E + +D + + K QD E K Q + + +
Sbjct: 975 QHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVK 1034
Query: 336 ---VIEQ---LYAKLSTSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNILD--KELENIVD 387
+IEQ +++ + + L+ + S + + +K D ++N++ ++ +EL + D
Sbjct: 1035 DNEIIEQQRKIFSLIQEKNELQQML-ESVIAEKEQLKT-DLKENIEMTIENQEELRLLGD 1092
Query: 388 EVQRKET-----KDSGIKWDSTISYTAQA---------ERTPDLTELRQQPV-ASEDISE 432
E+++++ K+ IK + +S T E++ L E +QQ + E++SE
Sbjct: 1093 ELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSE 1152
Query: 433 DSTKDN-VSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLSDNKSGQKVSEAKPS 491
K N + K + ++ T E+ +R + QK++E
Sbjct: 1153 MQKKINEIENLKNELKNKELTLEHMETERL------------------ELAQKLNE---- 1190
Query: 492 QYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLS--LTETKSQGGKSGTSMMMLEQFRK 549
Y E++ + K+RK +K + E +R HL + E ++ G ++ + + K
Sbjct: 1191 NYEEVKSITKERKVLKELQKS-----FETERDHLRGYIREIEATGLQTKEELKIAHIHLK 1245
Query: 550 VKRESPFDKRPTAAEIKVEP-TTESLDKEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGK 608
+E+ + R + +E + T+ L+K L E + ++ + P ++
Sbjct: 1246 EHQETIDELRRSVSEKTAQIINTQDLEKSHT----KLQEEIPVLHEEQELLPNVKEVSET 1301
Query: 609 KHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSN 668
+ ++ + +++ T++ L + ++ +L L+ +E+ E + L E+ N
Sbjct: 1302 QETMNELELLTEQSTTKDSTTLAR-IEMERL--RLNEKFQESQEEIKSLTK-----ERDN 1353
Query: 669 LEEFQEAIMAFLKQKIDNIGKAFDK--KTVPKEEELLKRAEAE-KLGIIKAKMEEYFQKV 725
L+ +EA+ Q ++I + K ++ K+E+ L E + + I ++ME++ K
Sbjct: 1354 LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKD 1413
Query: 726 AETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTD 785
+ + + +K+ ++ ++ M + +K + E +L ES D
Sbjct: 1414 SALLRIEIEMLGLSKRLQESHDE----------MKSVAKEKDDLQRLQE---VLQSES-D 1459
Query: 786 PVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLG 845
+ N+ +++ +E+E ++ K+ +E + + L E + ++S + + + +
Sbjct: 1460 QLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVN-LSEKETEISTIQKQLEAIN 1518
Query: 846 ER--NLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQ 903
++ N ++E YEK EE+ Q+ E +++ KQ++E K+ Q+ + +
Sbjct: 1519 DKLQNKIQEIYEK-----EEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLE 1573
Query: 904 EEKQKQRGQEEEEL---PKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHR 960
+ Q QEE ++ K ++R++E Q +E++ Q+++ K +
Sbjct: 1574 LTNRLQESQEEIQIMIKEKEEMKRVQEALQ--------IERD-----QLKENTKEIVAKM 1620
Query: 961 RREKGKEKQ--KPERGLEDLERQIKTKDQMQMKETQPKELEKM 1001
+ + KE Q K E E+ + + + ETQ LE +
Sbjct: 1621 KESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENI 1663
Score = 69.7 bits (169), Expect = 3e-11
Identities = 201/1025 (19%), Positives = 405/1025 (39%), Gaps = 188/1025 (18%)
Query: 64 EDIDMQLSEIMNNVHRIMTRYTLVFNSSSE-RNVSLT-EHKKKQRTNFLEKMATY---AK 118
++ QL + + + + + N +E +N LT EH + +R +K+ K
Sbjct: 1137 QEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVK 1196
Query: 119 TIEIREKTLANILAWLEEWNDVLS------EMTLMDVDE-----HHHWIAQMELLPDTLK 167
+I K L + E D L E T + E H H E + + +
Sbjct: 1197 SITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRR 1256
Query: 168 AI-ENNVKILSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISD 226
++ E +I++ K +++ +L + V + T + +++++
Sbjct: 1257 SVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE---QELLPNVKEVSETQETMNELELLTE 1313
Query: 227 QLATNTKVSEIQGMLQELIGTTMFSTLENNAIKYISSTIVNLST---ALSMLNDELKCVN 283
Q T + + ++ L F + IK ++ NL T AL + +D+LK
Sbjct: 1314 QSTTKDSTTLARIEMERLRLNEKFQESQEE-IKSLTKERDNLKTIKEALEVKHDQLK--E 1370
Query: 284 FQSSTVYAHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAK 343
T+ + S++++E SL + ++ NE + +++ + K L+R +I + L +
Sbjct: 1371 HIRETLAKIQESQSKQEQSLNM-KEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKR 1429
Query: 344 LSTSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDS 403
L S +++ K D + +L E + + + ++ K + +
Sbjct: 1430 LQESH----------DEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEEL 1479
Query: 404 TISYTAQAERTPDLTELRQQPVASEDISEDST--------KDNVSLKKGDFYQEDE---- 451
+++ E+ + ELR SE +E ST D + K + Y+++E
Sbjct: 1480 KVAHCCLKEQEETINELRVN--LSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNI 1537
Query: 452 ---------TDEYQSWKRSHKKATYVYETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKK 502
+E + +K H+KA + S ++K + + + SQ E+Q++ K+
Sbjct: 1538 KQISEVQEKVNELKQFKE-HRKA----KDSALQSIESKMLELTNRLQESQE-EIQIMIKE 1591
Query: 503 RKEMKSFSED-----------------KSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLE 545
++EMK E K K E + + L +T K + E
Sbjct: 1592 KEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKE 1651
Query: 546 QF--RKVKRESPFDKRPTAAEIKVEPTTE--SLDKEGKGEIRSLVEPLSMIQFDDTAEPQ 601
QF +K+ E+ + +I E E S+ KE + ++RS+ E L + +
Sbjct: 1652 QFETQKLNLENIETENIRLTQILHENLEEMRSVTKE-RDDLRSVEETLKV---------E 1701
Query: 602 KGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPD 661
+ ++K TIT EK EE + + +K HQ +++ ++ SE T + +
Sbjct: 1702 RDQLKENLRE----TITRDLEKQEELKIVHMHLKEHQ--ETIDKLRGIVSEKTNEISNMQ 1755
Query: 662 GKSEQSN----------LEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKL 711
E SN EE + A M LK++ + I K + V ++ + L + + L
Sbjct: 1756 KDLEHSNDALKAQDLKIQEELRIAHM-HLKEQQETIDKL--RGIVSEKTDKLSNMQKD-L 1811
Query: 712 GIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISA 771
AK++E Q++ +++ KD + + K VS M L Q
Sbjct: 1812 ENSNAKLQEKIQELKANEHQLITLKKDVNETQ----------KKVSEMEQLKKQ-----I 1856
Query: 772 KSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQ 831
K +S TL S+ +I ++ QK H+ E+ +
Sbjct: 1857 KDQSLTL----------------------SKLEIENLNLAQKLHENLEEMKS-------- 1886
Query: 832 EQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKE 891
++ ER+ L+ E + ++ K LQ + + + + Q++ + M +
Sbjct: 1887 -----------VMKERDNLRRVEETLKLERDQLKESLQETKAR-DLEIQQELKTARMLSK 1934
Query: 892 EQKQATPKQAEQ--------EEKQKQRGQEEEELPK--SSLQRLEEGTQKMKTQGLLLEK 941
E K+ K E+ + QK + ++EL K LQ+ E ++K + K
Sbjct: 1935 EHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHK 1994
Query: 942 ENGQMRQIQK--EAKHLGPHR-RREKGKEKQKPERGLEDLERQIKTKDQM-QMKETQPKE 997
+ +M Q++K EA++L R + + +K LE++ K +D++ ++KE+ E
Sbjct: 1995 KINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKME 2054
Query: 998 LEKMV 1002
++ +
Sbjct: 2055 RDQFI 2059
Score = 53.1 bits (126), Expect = 3e-06
Identities = 217/1058 (20%), Positives = 410/1058 (38%), Gaps = 171/1058 (16%)
Query: 7 NEIDNDPESEKCIKDSTIMRREPQ--NILSPLMLPNLEIPFSVKDIISRIERAQLHRARE 64
NE+ E K KDS + E + + + L EI +K E+ ++ R +E
Sbjct: 1548 NELKQFKEHRKA-KDSALQSIESKMLELTNRLQESQEEIQIMIK------EKEEMKRVQE 1600
Query: 65 DIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYAKTIEIRE 124
+ ++ ++ N I+ + S E+ + T EKM E E
Sbjct: 1601 ALQIERDQLKENTKEIVAK----MKESQEKEYQFLKMTAVNETQ--EKMCEIEHLKEQFE 1654
Query: 125 KTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKILSRFSTSFL 184
N L +E N L+++ +++E + D L+++E +K+
Sbjct: 1655 TQKLN-LENIETENIRLTQILHENLEEMRSVTKER----DDLRSVEETLKVER------- 1702
Query: 185 DEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLA--TNTKVSEIQGMLQ 242
D+ K+ ++ ++R L K + +++ L+ Q D+L + K +EI M +
Sbjct: 1703 DQLKENLRETITRD-LEKQEELKIVHMH-----LKEHQETIDKLRGIVSEKTNEISNMQK 1756
Query: 243 ELIGTTMFSTLENNAIKYISSTIVN-LSTALSMLNDELKCVNFQSSTVYAHETSEAEKEL 301
+L + N+A+K I L A L ++ + ++ V SE +L
Sbjct: 1757 DLEHS-------NDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIV-----SEKTDKL 1804
Query: 302 SLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPGPSPQSS 361
S + +DL N N LQ+K+Q+ + QLI K + + K+S LK Q
Sbjct: 1805 S-NMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLK------KQIK 1857
Query: 362 RAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTPDLTELR 421
+ + E N+ K EN+ + + +D+ + + T+ + ER L E
Sbjct: 1858 DQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETL----KLER-DQLKESL 1912
Query: 422 QQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLSDNKS 481
Q+ A + + K L K + ET + K S K +SD +
Sbjct: 1913 QETKARDLEIQQELKTARMLSK----EHKETVDKLREKISEKTI---------QISDIQ- 1958
Query: 482 GQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSM 541
+ + ++K ++Q L+KK ++ ED + S +K + + K Q SM
Sbjct: 1959 -KDLDKSKDELQKKIQELQKKELQLLRVKEDVNMS----HKKINEMEQLKKQFEAQNLSM 2013
Query: 542 MMLE----QFRKVKRESPFDKRPTAAE-IKVEPTTESLDKEGKGEIRSLVEPLSMIQFDD 596
+ Q K ES + R A E ++ ESL E I +L E ++ + +
Sbjct: 2014 QSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNH 2073
Query: 597 TAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRV 656
+P+K + + H+ T + +E+ + KE L + + + L+R++ + +
Sbjct: 2074 QVKPEKRLLSDGQQHL---TESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEI-- 2128
Query: 657 LESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKA 716
EFQ+ + +K + ++P L+ EKL
Sbjct: 2129 --------------EFQKELSMRVKANL----------SLP----YLQTKHIEKLFTANQ 2160
Query: 717 KMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKS---PISAKS 773
+ F ++ + + +L Y KEEQ K + F+ + QK I
Sbjct: 2161 RCSMEFHRIMKKLKYVL-SYVTKIKEEQ---HESINKFEMDFIDEVEKQKELLIKIQHLQ 2216
Query: 774 ESSTLLSYESTDPVINNLIQMILAEI---ESERDIPTVSTVQKDHKEKEKQRQEQYLQEG 830
+ + S E D +N + + + EI SE + P++ T + K+ Q+L+E
Sbjct: 2217 QDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKE-MTQFLEEW 2275
Query: 831 -------QEQMSGMSLKQQLLGE-RNLLKEHYEKI---SENWEEKKAWLQMKEGKQEQQS 879
++ +G+ + + + N I S +EE+ A + KE +Q+ +S
Sbjct: 2276 LNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATIS-KEWEQDLKS 2334
Query: 880 QKQWQEEEMWKEEQKQATP-------KQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKM 932
K+ + E+++K Q T Q+ K +L ++ LE +
Sbjct: 2335 LKE-KNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEA 2393
Query: 933 KTQGLLLEKENGQMRQ---------IQKEAKHLGPHRRREKGKEK-----------QKP- 971
K + E + +M++ + +AK ++ EK KE KP
Sbjct: 2394 KESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPY 2453
Query: 972 ERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTL 1009
+ +EDL+ ++ D +MK KE EK + T T+
Sbjct: 2454 KEEIEDLKMKLVKIDLEKMKNA--KEFEKEISATKATV 2489
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 85.1 bits (209), Expect = 7e-16
Identities = 174/817 (21%), Positives = 342/817 (41%), Gaps = 140/817 (17%)
Query: 284 FQSSTVYAHETSEAEKELSLKIIRDLSNENEMLQQ------KLQDAEEKCEQLIRSKIVI 337
FQ + ++ KEL K++ L +N++ Q L DAEE+CEQLI++KI +
Sbjct: 859 FQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQL 918
Query: 338 EQLYAKLS--TSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNI------LDKELENIVDEV 389
E +++ ++ + + + + + + ++D++ ++KE ++V
Sbjct: 919 EAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 978
Query: 390 QRKETKDSGIKWDSTISYTAQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQE 449
+ + +G+ D TI+ ++ ++ L E QQ + +D+ + K N+ L K E
Sbjct: 979 KNLTEEMAGL--DETIAKLSKEKKA--LQETHQQTL--DDLQAEEDKVNI-LTKAKTKLE 1031
Query: 450 DETDEYQSWKRSHKKATYVYETSGPNLS--------------------DNKSGQK----- 484
+ D+ + KK E + L D K +K
Sbjct: 1032 QQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEIS 1091
Query: 485 --VSEAKPSQYYELQVLKKKRKEMKSFSED---------KSKSPTEAKRKHLS-----LT 528
+S+ + Q E+Q L+KK KE+++ E+ S++ E +R LS ++
Sbjct: 1092 NLISKIEDEQAVEIQ-LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEIS 1150
Query: 529 ETKSQGGKSGTSMMMLEQFRKVKRESPFDKRP---TAAEIKVEPTTESLDKEGKGEIRSL 585
E + G + ++ + L + KRE+ F K A ++ E +L K+ + L
Sbjct: 1151 ERLEEAGGATSAQVELNK----KREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAEL 1206
Query: 586 VEPLSMIQ-FDDTAEPQKGKIKGKKHHISSGT-ITSKEEKTEEK----------EELTKQ 633
E + +Q E +K ++K + +SS SK + EK E TK+
Sbjct: 1207 GEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKE 1266
Query: 634 VKSHQLVKSL----SRVAKETSESTRVLESPD------GKSEQSNLEEFQEAIMAFLKQK 683
+ +L+ L +R+ E E +R L+ D +S+Q++ ++ +E LK +
Sbjct: 1267 EEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEE-----LKHQ 1321
Query: 684 IDNIGKAFDKKTVPKEEE------LLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYK 737
++ KA + + L ++ E E+ G KA+++ K V + KY
Sbjct: 1322 LEEETKAKNALAHALQSSRHDCDLLREQYEEEQEG--KAELQRALSKANSEVAQWRTKY- 1378
Query: 738 DTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILA 797
+T ++ E +KK+ Q++ ++ ++ S E T + N ++ ++
Sbjct: 1379 ETDAIQRTEELEEAKKKLAQ-----RLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLML 1433
Query: 798 EIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQ-----EQMSGMSLKQQLLGERNLLKE 852
++E ++ + +K +Q +E Q Q SL +L +N+ +E
Sbjct: 1434 DVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
Query: 853 HYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQ 912
+++ E K Q EQ ++ Q E+ K KQ EQE+ + Q
Sbjct: 1494 SLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK------IKKQVEQEKCEIQAAL 1547
Query: 913 EEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPE 972
EE E +SL+ EEG K + LE + Q++ E + E + K+
Sbjct: 1548 EEAE---ASLEH-EEG----KILRIQLE-----LNQVKSEVDRKIAEKDEEIDQLKRNHT 1594
Query: 973 RGLE----DLERQIKTK-DQMQMKETQPKELEKMVIQ 1004
R +E L+ +I+++ D +++K+ +L +M IQ
Sbjct: 1595 RVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQ 1631
Score = 54.3 bits (129), Expect = 1e-06
Identities = 96/447 (21%), Positives = 180/447 (40%), Gaps = 74/447 (16%)
Query: 618 TSKEEKTEEKEELTK-QVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAI 676
T KEE + K+EL K + K +L + + + KE ++ ++S E +L + +E
Sbjct: 854 TMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQS-----EADSLADAEERC 908
Query: 677 MAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKY 736
+K KI K + +EEE + K K K+E+ ++ + + +
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAK----KRKLEDECSELKKDIDDLELTL 964
Query: 737 KDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSES------STLLSYESTDPVINN 790
+KE+ E K K + M GL + +S + ++ TL ++ + +N
Sbjct: 965 AKVEKEKHATEN--KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 791 LIQMILAEIESERDIPTVSTVQKDHK------EKEKQRQEQYLQEGQEQMSGMSLKQQLL 844
L + A+ + E+ + + + K E+ K++ E L+ QE M +Q L
Sbjct: 1023 LTK---AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQL 1079
Query: 845 GER---------NLL-----------------KEHYEKISENWEEKKAWLQMKEGKQEQQ 878
E+ NL+ KE +I E EE +A + ++Q+
Sbjct: 1080 DEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQR 1139
Query: 879 SQKQWQEEEMWK--EEQKQATPKQAEQEEKQKQRGQE-EEELPKSSLQR----------- 924
S + EE+ + EE AT Q E +K++ Q+ +L +++LQ
Sbjct: 1140 SDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKH 1199
Query: 925 ------LEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDL 978
L E ++ LEKE +++ + + KG +K R LED
Sbjct: 1200 ADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGN-LEKMCRSLEDQ 1258
Query: 979 ERQIKTKDQMQMKETQPKELEKMVIQT 1005
++KTK++ Q + ++ +QT
Sbjct: 1259 VSELKTKEEEQQRLINDLTAQRARLQT 1285
Score = 33.5 bits (75), Expect = 2.5
Identities = 37/189 (19%), Positives = 88/189 (46%), Gaps = 19/189 (10%)
Query: 870 MKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEEL------PKSSLQ 923
+K + E++ +E + K+E ++ K+ E EEK +E+ +L SL
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 924 RLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPH---RRREKGKEKQKPERGLEDLER 980
EE +++ + LE + ++ + +E + + ++R+ E + ++ ++DLE
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
Query: 981 QI-KTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENL 1039
+ K + + E + K L + + T++ K K +Q +++ +TL++L
Sbjct: 963 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKE-KKALQETHQ--------QTLDDL 1013
Query: 1040 PDEKEPISI 1048
E++ ++I
Sbjct: 1014 QAEEDKVNI 1022
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 84.7 bits (208), Expect = 1e-15
Identities = 137/527 (25%), Positives = 192/527 (36%), Gaps = 61/527 (11%)
Query: 1092 AQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQTQV-----QGIT 1146
A Q I L G TP + +++ T +A+G P T V QG+
Sbjct: 2608 ATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVR 2667
Query: 1147 LTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVS 1206
+ ++ Q L PQ +QA G+ L + L QQ Q +
Sbjct: 2668 AVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQ 2727
Query: 1207 LTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPK-----QVQ 1261
QQ Q+ QQ Q T +Q Q G +P Q +A+G LTP+ Q Q
Sbjct: 2728 QQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVG-KLTPEHLIKMQKQ 2786
Query: 1262 ELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTP---Q 1318
+L +P P QA P ++ PQQ +T + AL T Q
Sbjct: 2787 KLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQ 2846
Query: 1319 QAQALGIPLTPQQAQTQEITLTPQQAQ-ALGMPLTTQQAQELGIPLTPQHAQALGMP-LT 1376
A+ +P + QAQ Q T PQ AQ AL P P+ A + P +T
Sbjct: 2847 VARLTRVPTSQLQAQGQMQTQAPQPAQVALAKP-----------PVVSVPAAVVSSPGVT 2895
Query: 1377 TQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLT 1436
T GI + A+G P + P+ QQ +L QQA Q+ +
Sbjct: 2896 TLPMNVAGISV------AIGQPQKAAGQTVVAQPVHMQQLLKL-----KQQAVQQQKAIQ 2944
Query: 1437 PQQAQ---ALGMPLTAQQAQELG----ITLTPQQAQELGIPLTP-QQAQAL-GIPLIPPQ 1487
PQ AQ A+ +TAQQ G + Q A + TP QAQ L G + Q
Sbjct: 2945 PQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQ 3004
Query: 1488 AQELGIPLTPQQAQALGILLIPPQAQELGIPLTPQQAQALG-------IPLIPPQAQELG 1540
Q +P QQ + + A + P T QA IP + AQ +
Sbjct: 3005 IQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQ 3064
Query: 1541 IPLTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQEL 1587
L QQV + + L+ P P AQ +P Q +L
Sbjct: 3065 QKLIQQQV-------VTTASAPLQTPGAPNPAQVPASSDSPSQQPKL 3104
Score = 72.0 bits (175), Expect = 6e-12
Identities = 127/476 (26%), Positives = 177/476 (37%), Gaps = 57/476 (11%)
Query: 1083 VGITLTPQQAQAQGITLTLQQAQELGIP---LTPQQAQALEILFTPQQAQALGIPLTPQQ 1139
V LTP Q A+ + + QA + +P +TP Q L QQ Q QQ
Sbjct: 2678 VTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQ-----QQQQ 2732
Query: 1140 TQVQGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQ-----QAQELGIP 1194
Q Q QQ Q + Q Q G +P Q +A+G LTP+ Q Q+L +P
Sbjct: 2733 QQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVG-KLTPEHLIKMQKQKLQMP 2791
Query: 1195 LTPQQAQALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGIT 1254
P QA S PQ ++ + T Q Q LT A + G LT G T
Sbjct: 2792 PQPPPPQA--QSAPPQPTAQVQVQ-TSQPPQQQSPQLTTVTAPRPGALLT-------GTT 2841
Query: 1255 LTPKQVQEL-GIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGI 1313
+ QV L +P + QAQ T P+ AQ + + P + + +P G+
Sbjct: 2842 VANLQVARLTRVPTSQLQAQGQMQTQAPQPAQ-VALAKPPVVSVPAAVVSSP------GV 2894
Query: 1314 PFTPQQAQALGIPL-TPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALG 1372
P + + + PQ+A Q + P Q L QQA + + PQ AQ
Sbjct: 2895 TTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQL--LKLKQQAVQQQKAIQPQAAQG-- 2950
Query: 1373 MPLTTQQ---AQELGIPLTPQQAQALGMP------LTTQQAQELGIPLTPQQAQELGIPF 1423
P QQ AQ++ P Q+ P LTT +Q + Q ++ +
Sbjct: 2951 -PAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAK 3009
Query: 1424 TPQQAQAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPL 1483
PQ Q Q + QQ + + Q T QQ Q IP AQ + L
Sbjct: 3010 LPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQM--IPAVTATAQVVQQKL 3067
Query: 1484 IPPQ-----AQELGIPLTPQQAQALGILLIPPQAQELGIPLTPQQAQALGIPLIPP 1534
I Q + L P P AQ P Q +L + + A L P PP
Sbjct: 3068 IQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQPKLQMRV---PAVRLKTPTKPP 3120
Score = 71.6 bits (174), Expect = 8e-12
Identities = 113/439 (25%), Positives = 156/439 (35%), Gaps = 49/439 (11%)
Query: 1075 LTPQQAQEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIP 1134
L PQ +Q G+ L + L QQ Q+ QQ Q + QQ Q
Sbjct: 2692 LVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTT 2751
Query: 1135 LTPQQTQVQGITLTPQQDQAPG----ISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQE 1190
Q Q+QG +P Q +A G L Q QKL +P P QA P P +
Sbjct: 2752 SQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQ 2811
Query: 1191 LGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQAQALGITL-TLQQAQQLGIPLTPQQAQ 1249
+ PQQ LT A G LT G T+ LQ A+ +P + QAQ
Sbjct: 2812 VQTSQPPQQQSP---QLTTVTAPRPGALLT-------GTTVANLQVARLTRVPTSQLQAQ 2861
Query: 1250 ALGITLTPKQVQELGIPLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQ 1309
T P+ Q + + P + + +P G+ P + + + Q +
Sbjct: 2862 GQMQTQAPQPAQ-VALAKPPVVSVPAAVVSSP------GVTTLPMNVAGISVAIGQPQ-K 2913
Query: 1310 ALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQ---AQELGIPLTPQ 1366
A G Q + QQA Q+ + PQ AQ P QQ AQ++ P Q
Sbjct: 2914 AAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQG---PAAVQQKITAQQITTPGAQQ 2970
Query: 1367 HAQALGMP------LTT--QQAQEL-GIPLTPQQAQALGMPLTTQQAQELG----IPLTP 1413
P LTT QAQ+L G Q Q +P QQ + +
Sbjct: 2971 KVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASAS 3030
Query: 1414 QQAQELGIPFTPQQAQAQEITLTP---QQAQALGMPLTAQQAQELGITLTPQQAQELGIP 1470
QQA + T A Q++ + P AQ + L QQ +T Q G P
Sbjct: 3031 QQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQV----VTTASAPLQTPGAP 3086
Query: 1471 LTPQQAQALGIPLIPPQAQ 1489
Q + P P+ Q
Sbjct: 3087 NPAQVPASSDSPSQQPKLQ 3105
Score = 65.5 bits (158), Expect = 6e-10
Identities = 163/693 (23%), Positives = 235/693 (33%), Gaps = 86/693 (12%)
Query: 1266 PLTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQAQALGI 1325
PL P Q +L K+ + L QQ P P Q Q P PQQ
Sbjct: 2471 PLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPP--PPQPQP---PPPPQQPPP--- 2522
Query: 1326 PLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQAQ-ELG 1384
PL QA + P Q P Q Q + P Q A G +
Sbjct: 2523 PLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTS 2582
Query: 1385 IPLTPQQAQAL----------GMPLTTQQA--QELGIPLTPQQAQELGIPFTPQQAQAQE 1432
+ T A+ G+P T Q+ + L P+ P G TP + +
Sbjct: 2583 VTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAP------GALTTPGGSAPAQ 2636
Query: 1433 ITLTPQQAQALGMPLTA-----QQAQELGITLTPQQAQELGIP--LTPQQAQALGIPLIP 1485
+ T +A+G P TA A G+ + LTP Q A L+P
Sbjct: 2637 VVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARS--LVP 2694
Query: 1486 PQAQELGIPLTPQQAQALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTP 1545
+Q G+ L + L+ Q Q+ QQ Q Q Q+ T
Sbjct: 2695 QVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQT---TTT 2751
Query: 1546 QQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQELGIPLTP 1605
QVQ +P I QAQ +P Q +A+G LTP+ L Q Q+L +P P
Sbjct: 2752 SQVQ---VPQIQGQAQ------SPAQIKAVG-KLTPEH-------LIKMQKQKLQMPPQP 2794
Query: 1606 QQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAWVSAVTLTS 1665
QAQ P P + S PQQ Q T+T + AL T N V+ +T
Sbjct: 2795 PPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVP 2854
Query: 1666 EQTHALESPMNLEQAQEQLLKLGVPLTLD-KAHTLGSP----LTLKQVQWSHRPFQKSKA 1720
+ M + Q + L P + A + SP L + S Q KA
Sbjct: 2855 TSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKA 2914
Query: 1721 SLPTGQSIISR-LSPSLRLSLASSAPTAEKSSIFGVSSTPLQISRVPLNQGPFAPGKPLE 1779
+ GQ+++++ + L L A +K+ + P + + Q PG +
Sbjct: 2915 A---GQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQK 2971
Query: 1780 MGILSEPGKLGAPQTLRSSGQTLVYGGQSTSAQFPAPQAPPSPGQLPISRAPPTPGQPFI 1839
+ ++P T S + G Q Q + P Q+ + P Q
Sbjct: 2972 VAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLP----QVVQQQTPVASIQQVA 3027
Query: 1840 AGVPPTSGQIPSLWAPLSPGQ-----PLVPEASSIPGDLL--------ESGPLTFSEQLQ 1886
+ S Q +L + GQ P V + + L S PL
Sbjct: 3028 SASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPN 3087
Query: 1887 EFQPPATAE---QSPYLQAPSTPGQHLATWTLP 1916
Q PA+++ Q P LQ P L T T P
Sbjct: 3088 PAQVPASSDSPSQQPKLQM-RVPAVRLKTPTKP 3119
Score = 52.0 bits (123), Expect = 7e-06
Identities = 98/429 (22%), Positives = 168/429 (39%), Gaps = 58/429 (13%)
Query: 878 QSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGL 937
Q +Q Q+++ +++Q+Q +Q +Q+++Q+Q+ ++ +Q + ++K G
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGK 2774
Query: 938 LLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKE----T 993
L + + ++QK+ + P + + + P + ++ Q Q Q + T
Sbjct: 2775 LTPE---HLIKMQKQKLQMPP--QPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVT 2829
Query: 994 QPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPS 1053
P+ + T L + + Q +G+ ++ + +++ PP
Sbjct: 2830 APRPGALLTGTTVANLQVARLTRVPTSQLQAQGQ--------MQTQAPQPAQVALAKPPV 2881
Query: 1054 LQYSLPGALPISGQPLTKCIHLTPQQAQEVGITLTPQQAQAQGITLTLQQAQELGIPLTP 1113
+ S+P A+ +S +T P + + + Q +A G T+ Q +
Sbjct: 2882 V--SVPAAV-VSSPGVT----TLPMNVAGISVAI-GQPQKAAGQTVVAQPVHMQQLLKLK 2933
Query: 1114 QQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQDQAPG----ISLTTQQAQKLGI 1169
QQA + PQ AQ P QQ +T QQ PG ++ Q A K
Sbjct: 2934 QQAVQQQKAIQPQAAQG---PAAVQQ------KITAQQITTPGAQQKVAYAAQPALKTQF 2984
Query: 1170 PLTP-QQAQAL-GIPLTPQQAQELGIPLTPQQ----AQALRVSLTPQQAQELGIPLTPQQ 1223
TP QAQ L G Q Q +P QQ A +V+ QQA + LT Q
Sbjct: 2985 LTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALT--Q 3042
Query: 1224 AQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQV-----QELGIPLTPQQAQALGIT 1278
A A G QQ Q IP AQ + L +QV L P P AQ +
Sbjct: 3043 ATAAG-----QQVQM--IPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASS 3095
Query: 1279 LTPKQAQEL 1287
+P Q +L
Sbjct: 3096 DSPSQQPKL 3104
Score = 46.6 bits (109), Expect = 3e-04
Identities = 53/218 (24%), Positives = 81/218 (37%), Gaps = 17/218 (7%)
Query: 1444 GMPLTAQQAQELGITLTPQQAQ-ELGIPLTPQQAQALGIPLIPPQAQELGIPLT------ 1496
GMP T Q AQ G + QQ G P+ + +P +P + G+P
Sbjct: 515 GMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSAL 574
Query: 1497 -----PQQAQALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTP--QQVQ 1549
PQ +A L IP + Q+ +P+ + L IP P L +P TP QVQ
Sbjct: 575 QFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVP-TPGKVQVQ 633
Query: 1550 ALGIPLIPPQAQELEIPLTPQQAQALGIPL--TPQQAQELGIPLTPQQAQELGIPLTPQQ 1607
A + +P +P+ P +P T A G P A+ +
Sbjct: 634 ASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSA 693
Query: 1608 AQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQ 1645
P+T + + + T Q+ AQ T + +Q
Sbjct: 694 TNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQ 731
Score = 40.8 bits (94), Expect = 0.016
Identities = 49/219 (22%), Positives = 82/219 (37%), Gaps = 7/219 (3%)
Query: 1132 GIPLTPQQTQVQGITLTPQQ-DQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQE 1190
G+P TPQ Q+ G + QQ D + G + + +P P + G+P T +
Sbjct: 515 GMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVP-TAALSSA 573
Query: 1191 LGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTP--QQA 1248
L PQ +A P + Q+ +P+ + L I + L +P TP Q
Sbjct: 574 LQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVP-TPGKVQV 632
Query: 1249 QALGITLTPKQVQELGIPLTPQQ--AQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPK 1306
QA ++ P+ V +P+ P + L + T A G P A++ +
Sbjct: 633 QASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSS 692
Query: 1307 QAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQ 1345
P T + + T Q+ Q T + +Q
Sbjct: 693 ATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQ 731
Score = 38.9 bits (89), Expect = 0.060
Identities = 49/176 (27%), Positives = 72/176 (40%), Gaps = 25/176 (14%)
Query: 1366 QHAQA-LGMPLTT-QQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPF 1423
QH A G+PL + G+P TPQ AQ G +Q+Q+ P T Q
Sbjct: 495 QHPGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQ----RQSQQQYDPSTGPPVQNAASLH 550
Query: 1424 TPQQAQAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQAQ---ELGIPLTPQQAQALG 1480
TP + P + G+P TA + L PQ + +L IP+ QQ
Sbjct: 551 TP-------LPQLPGRLPPAGVP-TAALSSALQFAQQPQVVEAQTQLQIPVKTQQP---N 599
Query: 1481 IPLIPPQAQELGIPLTPQQAQALGILLIPP---QAQELGIPLTPQQAQALGIPLIP 1533
+P+ P + +L IP P Q L + + P Q Q + PQ + +P+ P
Sbjct: 600 VPIPAPPSSQLPIP--PSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDP 653
Score = 38.9 bits (89), Expect = 0.060
Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 7/142 (4%)
Query: 1360 GIPLTPQHAQALGMPLTTQQAQ-ELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQE 1418
G+P TPQ AQ G + QQ G P+ + +P + G+P T +
Sbjct: 515 GMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVP-TAALSSA 573
Query: 1419 LGIPFTPQQAQAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPL-TP--QQ 1475
L PQ +AQ P + Q +P+ A + +L I P Q +L + + TP Q
Sbjct: 574 LQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPI--PPSQPAQLALHVPTPGKVQ 631
Query: 1476 AQALGIPLIPPQAQELGIPLTP 1497
QA + +P +P+ P
Sbjct: 632 VQASQLSSLPQMVASTRLPVDP 653
Score = 37.0 bits (84), Expect = 0.23
Identities = 42/148 (28%), Positives = 57/148 (38%), Gaps = 15/148 (10%)
Query: 1076 TPQQAQEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQALEILFTPQQA--QALGI 1133
TPQ AQ G + QQ +Q A L PL PQ L P A AL
Sbjct: 519 TPQAAQLAGQRQSQQQYDPS-TGPPVQNAASLHTPL-PQLPGRLPPAGVPTAALSSALQF 576
Query: 1134 PLTPQQTQVQGITLTPQQDQAPGISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGI 1193
PQ + Q P + Q P + + + +L IP + AL +P TP +
Sbjct: 577 AQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVP-TPGKV----- 630
Query: 1194 PLTPQQAQALRVSLTPQQAQELGIPLTP 1221
Q QA ++S PQ +P+ P
Sbjct: 631 -----QVQASQLSSLPQMVASTRLPVDP 653
Score = 36.2 bits (82), Expect = 0.39
Identities = 41/168 (24%), Positives = 61/168 (36%), Gaps = 25/168 (14%)
Query: 1233 LQQAQQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQALGITLTPKQAQELGIPLN 1292
L Q G+P TPQ AQ G +Q Q+ P T Q TP
Sbjct: 508 LMPTAQGGMPPTPQAAQLAG----QRQSQQQYDPSTGPPVQNAASLHTP----------- 552
Query: 1293 PQQAQTLGIPLTPKQAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLT 1352
+P P + G+P T + AL PQ + Q P + Q +P+
Sbjct: 553 --------LPQLPGRLPPAGVP-TAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIP 603
Query: 1353 TQQAQELGIPLTPQHAQALGMPLTTQ-QAQELGIPLTPQQAQALGMPL 1399
+ +L IP + AL +P + Q Q + PQ + +P+
Sbjct: 604 APPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPV 651
Score = 31.6 bits (70), Expect = 9.6
Identities = 60/278 (21%), Positives = 100/278 (35%), Gaps = 24/278 (8%)
Query: 1831 PPTPGQPFIAGVPPTSGQIPSLW-APLSPGQPLVPEASSIPGDLLESGPLTFSEQLQEFQ 1889
PP+P PF P++ Q PS L P + +I L GP+ Q
Sbjct: 35 PPSPAAPFAPSASPSAPQSPSYQIQQLMNRSPATGQNVNI--TLQSVGPVVGGNQQITLA 92
Query: 1890 P-PATAEQSPYLQAPSTPGQHLATWTLPGRASSLWIPPTSRHPPTLWPSPAPGKPQKSWS 1948
P P + SP Q + P + + +S PT PSP PG+ ++
Sbjct: 93 PLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQQVQTQSPT-QPSPGPGQALQNVR 151
Query: 1949 PSVAKKRLAIISSLKSKSVLIHPSAPDFKVAQVPFTTKKFQMSEVSDTSE-------ETQ 2001
L + SS + + S +++ P + F + S ++ + Q
Sbjct: 152 AGAPGPGLGLCSSSPTGG-FVDASVLVRQISLSPSSGGHFVFQDGSGLTQIAQGAQVQLQ 210
Query: 2002 ILRDTFAIESFRTFQSHFTKYRTPVYQTPYTDERALLTLMKPTTSPSSLTTLLRTSQISP 2061
+ R Q H T + P + A ++P SPS +TT QIS
Sbjct: 211 HPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAGGAGLQPLASPSHITTANLPPQISS 270
Query: 2062 L------EWYQKSRFPPIDKPWILSSVSDTKKPKVMVP 2093
+ + Q + PP+ +P + + P V++P
Sbjct: 271 IIQGQLVQQQQVLQGPPLPRP-----LGFERTPGVLLP 303
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 84.3 bits (207), Expect = 1e-15
Identities = 165/826 (19%), Positives = 336/826 (40%), Gaps = 120/826 (14%)
Query: 291 AHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVI------------E 338
AH + +++LS + + D + LQ KL EE+ ++ + + + E
Sbjct: 433 AHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQE 492
Query: 339 QLYAKLSTSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSG 398
Q + ST++ L+ Q R I N++ +L K ENI + KE +D
Sbjct: 493 QQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENI--SLLEKEREDLY 550
Query: 399 IKWDSTISYTAQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSW 458
K + TA + + Q+ V ++E + S K+ D+ E ++
Sbjct: 551 AKIQAGEGETAVLNQLQEKNHTLQEQVTQ--LTEKLKNQSESHKQAQENLHDQVQEQKAH 608
Query: 459 KRSHKKATYVYETSGPNLSD--NKSGQKVSE-----------------AKPSQYYELQ-- 497
R+ + ETS L+ N+S +KVS+ AK +Q +LQ
Sbjct: 609 LRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNH 668
Query: 498 ------VLKKKRKEMKSFSE--DKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLEQFRK 549
L+ K++E+ + D+ + + K++H S E+ + K + LEQ +
Sbjct: 669 LDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKE--KYLSLEQKTE 726
Query: 550 VKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKK 609
+ E+K D + + ++ + +E L + E +K
Sbjct: 727 ELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLE-LRATELSKQLEMEK------- 778
Query: 610 HHISSGTITSKEEKTEE----KEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSE 665
I S T ++K+E K++LTKQ + Q++K + + S+ T++
Sbjct: 779 -EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILK---QDFETLSQETKIQHEELNNRI 834
Query: 666 QSNLEEFQ------EAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKME 719
Q+ + E Q EA+M L D + K D LK +++E E
Sbjct: 835 QTTVTELQKVKMEKEALMTELSTVKDKLSKVSDS---------LKNSKSE--------FE 877
Query: 720 EYFQKVAETVTKILRKYKDTKKEEQVG-EKPIKQKKVVSFMPGLHFQKSPISAKSESSTL 778
+ QK + + + K+ K + QV E +K++K + K + + E+S
Sbjct: 878 KENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKEL---------KKSLEKEKEASHQ 928
Query: 779 LSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMS 838
L E + + LIQ ++E++ + + K+ +Q+++Q E +
Sbjct: 929 LKLE-LNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVL 987
Query: 839 LKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQE--QQSQKQWQEEEMWKEEQKQA 896
K +L N L++ + ++ +K + + + E Q++ KQ Q + +E + A
Sbjct: 988 QKTEL---ENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLA 1044
Query: 897 TPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQM-RQIQKEAKH 955
T + + E++ QE+ ++ + + Q++KT LE+++ + +Q+Q+ K
Sbjct: 1045 TRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKA 1104
Query: 956 LGPHRRREKGKEKQ----------------KPERGLEDLERQIKTKDQMQMKE-TQPKEL 998
L ++ + KEK+ + E+ + L ++K+ +KE T K+
Sbjct: 1105 LQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDA 1164
Query: 999 EKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKE 1044
++++IQ + L + S+ V++ ++ ++ E +KE
Sbjct: 1165 KQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKE 1210
Score = 77.8 bits (190), Expect = 1e-13
Identities = 217/1099 (19%), Positives = 443/1099 (40%), Gaps = 164/1099 (14%)
Query: 4 KMKNEIDNDPESEKCIKDSTIMRREPQNILSPLMLPNLEIPFSVKDIISRIERAQLHRAR 63
K+K+ ++ + + + ++ + + + LE + + + + +A LH+
Sbjct: 292 KLKSSVNELTQKNQTLTENLLKKEQDYT--------KLEEKHNEESVSKKNIQATLHQ-- 341
Query: 64 EDIDMQ-----LSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYAK 118
+D+D Q LS ++HRI + E L E + T + A + +
Sbjct: 342 KDLDCQQLQSRLSASETSLHRIHVE----LSEKGEATQKLKEELSEVETKYQHLKAEFKQ 397
Query: 119 TIEIREKTLANILAWLEEWNDVLSEM--TLMDVDEHHHWIA-QMELLPDTLKAIENNVKI 175
+ RE+ + L E N + S++ T + E H + Q +L + L E V
Sbjct: 398 LQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVAD 457
Query: 176 LSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVS 235
L + S L+E+ K+K ++ T + ++ ++ +AL Q +T K+
Sbjct: 458 L-QLKLSRLEEQLKEK---VTNSTELQHQLDKTKQQHQEQQAL--------QQSTTAKLR 505
Query: 236 EIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAH-ET 294
E Q L++++ I I NL L + + + + +YA +
Sbjct: 506 EAQNDLEQVL----------RQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQA 555
Query: 295 SEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRS-KIVIEQLYAKLSTSSTLKVL 353
E E ++ L +N LQ+++ EK + S K E L+ ++
Sbjct: 556 GEGETA----VLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQV--------- 602
Query: 354 PGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETK-DSGIKWDSTISYTAQAE 412
Q +A ++ EL + ++E + K ++ D IK + + +A+A
Sbjct: 603 -----QEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAA 657
Query: 413 RTPDLTELRQQPVASEDISEDSTK---------DNVSLKKGDFYQEDETDEYQSWKRSHK 463
+T +L+ +++ +D + D V+ K D +++ + +S + +K
Sbjct: 658 KTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQD--KQEHCSQLESHLKEYK 715
Query: 464 KATYVYETSGPNLSDN--KSGQKVSEAKPSQYYELQVLKKKR--------------KEMK 507
+ E L K E K S+ LQ L+++R K+++
Sbjct: 716 EKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLE 775
Query: 508 SFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLEQ-FRKVKRESPFDK-------R 559
E S + + ++K +L K + K +L+Q F + +E+ +
Sbjct: 776 MEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQ 835
Query: 560 PTAAEI-KVEPTTESLDKE---GKGEIRSLVEPLSMIQFDDTAEPQKGKI---------K 606
T E+ KV+ E+L E K ++ + + L + + E QKGK K
Sbjct: 836 TTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCK 895
Query: 607 GKKHHISSGTITSKEEKTEEKEELTKQVK-SHQLVKSLSRVAKETSESTRVLESPDGKSE 665
KH + + +E+ E K+ L K+ + SHQL L+ + ++ ++ L+ + + +
Sbjct: 896 ELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQ 955
Query: 666 Q--SNLEEFQ----------EAIMAFLK----QKIDNIGKAFDKKTVPKEEELLKRAEAE 709
Q N+ E + EA+ LK QK + K + T +E AE E
Sbjct: 956 QLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQE---LAAEKE 1012
Query: 710 KLGIIK---AKMEEYFQKVAETV----TKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGL 762
K+ +++ K +E F+++ +++L +D K E+ + + Q+ ++S +
Sbjct: 1013 KISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEE--KLSLAQEDLISNRNQI 1070
Query: 763 HFQKSPISAKSESSTLLSYESTDPVINNLIQ---MILAEIESERDIPTVSTVQKDHK--- 816
Q I + L +S +Q L +I+ E+ + V + K
Sbjct: 1071 GNQNKLIQELKTAKATLEQDSAKK--EQQLQERCKALQDIQKEKSLKEKELVNEKSKLAE 1128
Query: 817 -EKEKQRQEQYLQEGQEQMSGMSLKQ-----QLLGERNLLKEHYEKISENWEEKKAWL-Q 869
E+ K RQE+ + + E++ L+ L + LL + ++ + KA + Q
Sbjct: 1129 IEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQ 1188
Query: 870 MKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQ--RLEE 927
K +Q + Q + +EEE+ KE ++ +E +EK+ + EE K ++Q L E
Sbjct: 1189 EKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNE 1248
Query: 928 GTQKMKTQGLLLEKENGQMRQIQKEAKHL-GPHRRREKGKEKQKPERGLEDLERQIKTKD 986
+K + + ++ +++K+ L G E + + ER LER +K +
Sbjct: 1249 NLGTVKKE---WQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRAL-LERCLKGEG 1304
Query: 987 QMQMKETQPKELEKMVIQT 1005
+++ +T+ EL++ + T
Sbjct: 1305 EIEKLQTKVLELQRKLDNT 1323
Score = 33.5 bits (75), Expect = 2.5
Identities = 41/213 (19%), Positives = 88/213 (41%), Gaps = 20/213 (9%)
Query: 844 LGERNLLKEHYEKISENWEEK----KAWLQMKEG-----KQEQQSQKQWQEEEMWKEEQ- 893
LG + L +HYE + + + ++ L +K +QE Q + +EE W E+
Sbjct: 50 LGSADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEEL 109
Query: 894 -KQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGL-------LLEKENGQ 945
K+ Q Q+++ K G + + LQ LE+ ++ +T+ L E++ Q
Sbjct: 110 KKELEKYQGLQQQEAKPDGLVTDS--SAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQ 167
Query: 946 MRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQT 1005
+ + K R + +QK R E+L ++ ++ + Q +E + +
Sbjct: 168 LATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLK 227
Query: 1006 PMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLEN 1038
+ + ++R E ++ + K L++
Sbjct: 228 KELVQVQTLMDNMTLERERESEKLKDECKKLQS 260
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 84.0 bits (206), Expect = 2e-15
Identities = 212/1109 (19%), Positives = 446/1109 (40%), Gaps = 184/1109 (16%)
Query: 48 KDIISRIERAQLHRAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRT 107
K+++ R E +AR+ + ++ ++++ + ++F + KK+++
Sbjct: 1340 KEVMPREEEQAQKKARDMLGLEETQVI-----LKKGKKVIFLEPGNVTMGKEISKKEEKK 1394
Query: 108 NFLEKMATYAKTIEIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLK 167
F + K ++ K + EMT + D + +M L + +
Sbjct: 1395 TFQKSPKQGRKAVQKERKV-----------GKIKREMTKEERDMSEE-VEEMATLEEKVV 1442
Query: 168 AIENNVKILSRFSTSFLDEKKKQKKKILSRGTL---WKSWKERVIKRPSTARALRPDQMI 224
E + ++ R + S+ D KK + G WK+WKE K R L+ ++ +
Sbjct: 1443 KQEGKLVMIER-TPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEK-----RLLQEEEKL 1496
Query: 225 SDQLATNTKVSEIQGMLQE----------LIGTTMFSTLENNAIKYISSTIVNLSTALSM 274
K+S + MLQE + M S+ ++ +Y V L +S
Sbjct: 1497 HQ---AGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSS-KSKEQQYKDEEEVTLEEEVSR 1552
Query: 275 LND--ELKCVNFQSSTVYAHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIR 332
+ E + Q H+ + ++ + + E ++ Q++ + A+E+ QL +
Sbjct: 1553 EGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEE-RQLAQ 1611
Query: 333 SKIVIEQLYAKLSTSS-TLKVLPGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQR 391
+ + Q Y K++ + G Q + + G+ L +E E +
Sbjct: 1612 EERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEK-------LSQEAEKLA----- 1659
Query: 392 KETKDSGIKWDSTISYTAQ-AERTPDLTELRQQPVASEDISE-DSTKDNVSLKKGDFYQE 449
++ K KW+ + A++ L E++ + ++ + E + N+ ++ + QE
Sbjct: 1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKN--ILAQKVEELPQREQNLDWQEKELAQE 1717
Query: 450 DETDEYQ----SWKR---SHKKATYVYETSGPNLSDNKSG-----QKVSEAKPSQYYELQ 497
E E+ SWK + ++ V E L++ + +K+SE + E +
Sbjct: 1718 LEELEWDMEELSWKEEELNQEEGKLVEEKK--KLAEEEEALAWQREKLSEEETKLAQEEE 1775
Query: 498 VLKKKRKEMKSFSEDKSKSPTEAKR----------KHLSLTETKSQGGKSGTSMMMLEQF 547
+L ++++++ ++ K K P E +R K + L + + + S + +
Sbjct: 1776 LLIQEKEKL---AQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMI 1832
Query: 548 RKVKRESPFDKRPTAAE-IKVEPTTESL--DKE----GKGEIRSLVEPLSMI-----QFD 595
K+ +K+ A E K+ E+L +KE K ++ + L M Q +
Sbjct: 1833 LYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVE 1892
Query: 596 DTAEPQKGKIKGKKHHIS---------SGTITSKEEK-TEEKEELTKQ---VKSHQLVKS 642
+ +K + KK ++ ++ K+EK +EK +L + V+ + ++
Sbjct: 1893 EKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRG 1952
Query: 643 LSRVAKE-----------TSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAF 691
+AKE E R++E + S+ E ++ M ++Q++ +
Sbjct: 1953 ELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSL 2012
Query: 692 DKKTVPKEEELLKRAEAEKLGIIKAKME-----EYFQKVAETVTKILRKYKDTKKEEQVG 746
++K + E+ +L E+E I K K+E F + + K RK KK E +
Sbjct: 2013 EEKILLHEDRILAMEESE---IAKGKLEFTRGQRIFVQGQRKLAKASRKL--IKKRESLS 2067
Query: 747 EKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIP 806
++P K K++ + L + ++ + T + I+ +I+
Sbjct: 2068 KEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSE 2127
Query: 807 TVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEE--- 863
S + KD EK+ R+++ L +M ++ E L ++H E I ++ EE
Sbjct: 2128 KRSELTKD--EKKLARKQRKLANKMRRMINKE-EKMTEEESKLARKHSEVILDDEEEGGI 2184
Query: 864 ---------KKAWLQMKEGKQ-------------EQQSQKQWQE--EEMWKEEQKQATPK 899
K+ W + KE K+ E +S++ + E E + E +KQ +
Sbjct: 2185 EEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLS 2244
Query: 900 QAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPH 959
E+EE++++ +EEEE+ + +R EE E G+ +Q++KE +
Sbjct: 2245 SEEEEEREEEEEREEEEVREEEEERKEE--------------EEGEEKQVEKEEEEKKKK 2290
Query: 960 RRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKE----LEKMVIQTPMTLSPRWKS 1015
++ +K +E Q+ E E+ E + ++ + + + +E LE+ V + L +
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQF 2350
Query: 1016 VLKDVQR-SYEGKEFQRNLKTLENLPDEK 1043
L++ +R S G+E R L L +P K
Sbjct: 2351 KLQEQRRKSLRGRE--RVLSILRGVPHGK 2377
Score = 78.6 bits (192), Expect = 7e-14
Identities = 154/823 (18%), Positives = 343/823 (41%), Gaps = 81/823 (9%)
Query: 258 IKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETSEA-EKELSLKIIRDLSNENEML 316
I + T++N+ S+L + CV +++ S A E + +++ D +N N ++
Sbjct: 879 INSMIETMLNIMVHASLLKYQC-CVGALGQIFASYQVSPALRSETARRLLNDTTNSNPLI 937
Query: 317 QQKLQDAEEKCEQLI----------------RSKIVIEQLYAKLSTSSTLKVLPGPSPQS 360
++ + ++ + R +I L A++ S +L Q
Sbjct: 938 RELAWEGLKRLGMITHLFAMPLAQGLMDKDERVRIKTLSLMAEIGIHSRTSLLQLTQKQE 997
Query: 361 S-RAIIKVGDTEDNMDNILDK---ELENIVDEVQRKETKDSGIKW-DSTISYTAQAERTP 415
+ R + + E+ +D++L +L+ + +V+++ ++ + D +++
Sbjct: 998 TFREMQQQMIGEEPLDHLLGMRATDLQILSTQVEQRLNENLTLSHRDEKPAFSLDVSMPS 1057
Query: 416 DLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPN 475
+L + P SE+ SE + K + ++G + + ++ + K+ ++ P
Sbjct: 1058 ELKSSLKPPTVSEE-SEVAIKPSKGQRRGQAGVKKHSQKWLRGLKKTKERDSKQMSTEPG 1116
Query: 476 LSDNKSGQKVSEAKPSQYYELQVLKK--KRKEMKSFSEDKSKSPTEAKRKHLSLT----- 528
L +++SG +EA P + E V + + S+D + + H++LT
Sbjct: 1117 LLEDESG---TEAAPIEMEEASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQ 1173
Query: 529 ETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEI-----R 583
+ + + K T+ + ++ +K +E+ T + +P T+ + +G+G R
Sbjct: 1174 KIRDKRDKKATAQKLKKKHKKKGKEAKVINEETTPPVMEQPVTKKVKIQGRGASGISGRR 1233
Query: 584 SLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSL 643
S S + DD +I G + +S + E T +E L + S +L + +
Sbjct: 1234 STAGDGSSWR-DDLCRLMALRISGSQTKMSEN--LNAELVTFAQEMLVDRHPSWELFQEI 1290
Query: 644 SRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAF--DKKTVPKEEE 701
+ K+ ES +LE D + A + I + + K+ +P+EEE
Sbjct: 1291 CPLLKK--ESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEE 1348
Query: 702 LLKRAEAEKLG-------IIKAKMEEYFQKVAETVTKILRKYKDTK---KEEQVGEKPI- 750
++ + LG + K K + + T+ K + K ++ K K + G K +
Sbjct: 1349 QAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQ 1408
Query: 751 KQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAE-IESERDIPTVS 809
K++KV + ++ +S + E L + V+ ++++ E S +D
Sbjct: 1409 KERKVGKIKREMTKEERDMSEEVEEMATLE----EKVVKQEGKLVMIERTPSWQDWKKAW 1464
Query: 810 TVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISEN----WEE-K 864
K + ++ + + +E ++++ K GE+ L E + E+ WEE K
Sbjct: 1465 DEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEK--LSPEEEMLQEDKKLKWEEWK 1522
Query: 865 KAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRG-QEEEELPKSSLQ 923
+ W M K ++Q K EEE+ EE+ ++ EQ+ ++QR QEE + + +
Sbjct: 1523 QVWENMLSSKSKEQQYK--DEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRK 1580
Query: 924 RLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRR--EKGKEKQKPERGLEDLERQ 981
R ++ + + L ++E ++ +E + L R+ + + + +R + E +
Sbjct: 1581 RARAEKKRAQEERKLAQEE----EKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Query: 982 IKTKDQ--MQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQR 1022
K++ Q E +E EK+ Q L+ +W+ V ++ ++
Sbjct: 1637 FAQKEETLAQRGEKLSQEAEKLA-QKRKKLAKKWEKVAREEEK 1678
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 84.0 bits (206), Expect = 2e-15
Identities = 172/849 (20%), Positives = 338/849 (39%), Gaps = 136/849 (16%)
Query: 295 SEAE-KELSLKIIRDLSNENEMLQQ------KLQDAEEKCEQLIRSKIVIEQLYAKLSTS 347
SEA KEL K++ L +N++ Q L DAEE+CE LI+SKI++E +L+
Sbjct: 870 SEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELT-- 927
Query: 348 STLKVLPGPSPQSSRAIIKVGDTEDNMDNI------LDKELENIVDEVQRKETKDSGIKW 401
+ L +S + K + ED ++ L+ L + E E K +
Sbjct: 928 ---ERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSE 984
Query: 402 DSTI---SYTAQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSW 458
+ T + + + L E QQ + + ED L K + E +TD+ +
Sbjct: 985 EMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVN---GLIKINAKLEQQTDDLEGS 1041
Query: 459 KRSHKKATYVYETSGPNLSDN------------KSGQKVSEAKPSQYYELQVLKKK---- 502
KK E + L + Q++ E + +EL L+ K
Sbjct: 1042 LEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDE 1101
Query: 503 -------RKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGG---------------KSGTS 540
+K++K + E + +H + + Q SG +
Sbjct: 1102 QVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGAT 1161
Query: 541 MMMLEQFRKVKRESPFDKRP---TAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQ-FDD 596
+E + KRE+ F K A ++ E T +L K+ + L E + +Q
Sbjct: 1162 SAQIEMNK--KREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQ 1219
Query: 597 TAEPQKGKIKGKKHHISSG----------------TITSKEEKTEEKEELTKQVKSHQLV 640
E +K ++K + ++S T+ + + + K+E Q+ H L
Sbjct: 1220 KLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQL-IHDLN 1278
Query: 641 KSLSRVAKETSESTRVLESPDG------KSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKK 694
+R+ + E + +E + KS+Q+ ++ +E LK++++ KA +
Sbjct: 1279 MQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEE-----LKRQMEEETKAKNAM 1333
Query: 695 TVPKEEEL----LKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPI 750
+ L R + E+ KA+++ K V + KY +T ++ E
Sbjct: 1334 AHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKY-ETDAIQRTEELEE 1392
Query: 751 KQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVST 810
+KK+ Q++ + ++ +S S E T + ++ ++ ++ ER +T
Sbjct: 1393 AKKKLAQ-----RLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDL--ERSHTACAT 1445
Query: 811 VQKDHKEKEKQRQE--QYLQEGQEQMSGMSLKQQLLG-ERNLLKEHYEKISENWEEKKAW 867
+ K + +K E Q L E Q ++ + + L E ++ YE++ + E +
Sbjct: 1446 LDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLR-- 1503
Query: 868 LQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEE 927
+ K QEE EQ T K ++ EK K+ ++E+ + +L+ +E
Sbjct: 1504 ----------RENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEG 1553
Query: 928 GTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTK-- 985
+ +++ L ++ E + Q++ E + E + K+ +R E L+ + +
Sbjct: 1554 SLEHEESKILRVQLE---LSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIR 1610
Query: 986 ---DQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEG--KEFQRNL-KTLENL 1039
D +++K+ +L +M IQ + S R + + R+ +G K+ Q +L L +
Sbjct: 1611 SRNDALRLKKKMEGDLNEMEIQ--LGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSN 1668
Query: 1040 PDEKEPISI 1048
D KE ++I
Sbjct: 1669 EDLKEQLAI 1677
Score = 47.4 bits (111), Expect = 2e-04
Identities = 166/947 (17%), Positives = 385/947 (40%), Gaps = 127/947 (13%)
Query: 56 RAQLHRAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMAT 115
RA L RA+ ++ L ++ + + ++ L++ + K ++
Sbjct: 1049 RADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAK-----IDDEQV 1103
Query: 116 YAKTIEIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKI 175
++ + + K L + LEE ++ +E TL E Q L L+ I ++
Sbjct: 1104 HSLQFQKKIKELQARIEELEE--EIEAEHTLRAKIEK-----QRSDLARELEEISERLEE 1156
Query: 176 LSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLAT-NTKV 234
S +++ ++ KK++ + + + +E ++ +TA LR Q +D +A ++
Sbjct: 1157 ASGATSAQIEMNKKREAEFQK---MRRDLEEATLQHEATAATLRKKQ--ADSVAELGEQI 1211
Query: 235 SEIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHET 294
+Q + Q+L +E I ++S I LS + S + + V Q S + A +
Sbjct: 1212 DNLQRVKQKLEKEKSELKME---IDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDE 1268
Query: 295 SEAE--KELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVI----EQLYAKLSTSS 348
+ + +L+++ R L +N L ++++ E QL +SK + E+L ++ +
Sbjct: 1269 QQTQLIHDLNMQKAR-LQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEET 1327
Query: 349 TLKVLPGPSPQSSR----AIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDST 404
K + QSSR + + + E L + L EV + TK
Sbjct: 1328 KAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE------- 1380
Query: 405 ISYTAQAERTPDLTE----LRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEY-QSWK 459
T +RT +L E L Q+ +E+ +E + SL+K + E ++ + +
Sbjct: 1381 ---TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLE 1437
Query: 460 RSHKK-ATYVYETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRK-------EMKSFSE 511
RSH AT + + + QK+ E++ EL+ +K+ + +M++ E
Sbjct: 1438 RSHTACATLDKKQRNFDKVLAEWKQKLDESQA----ELEAAQKESRSLSTELFKMRNAYE 1493
Query: 512 DKSKSPTEAKRKHLSLTETKS----QGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKV 567
+ +R++ +L E S Q ++G ++ E+ +K+ + D ++ +
Sbjct: 1494 EVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSD-----LQVAL 1548
Query: 568 EPTTESLDKEGKGEIRSLVE--------PLSMIQFDDTAEPQKGKIKGKKHHISS---GT 616
E SL+ E +R +E +I+ D+ E K + + S
Sbjct: 1549 EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAE 1608
Query: 617 ITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNL------- 669
I S+ + K+++ + ++ L ++ +E+ + L + G+ + S L
Sbjct: 1609 IRSRNDALRLKKKMEGDLNEMEI--QLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALR 1666
Query: 670 --EEFQEAIM------AFLKQKIDNIGKAFDKKTVPK---EEELLKRAEAEKL------G 712
E+ +E + L ++++ + A ++ + E+ELL ++ +L
Sbjct: 1667 SNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTS 1726
Query: 713 IIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAK 772
+I K ++ +A+ ++ ++++ E+ +K I +++ K
Sbjct: 1727 LINTK-KKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAE-----------ELK 1774
Query: 773 SESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQE 832
E T E + ++ + ++ + ++ K + + R+ + + ++
Sbjct: 1775 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQ 1834
Query: 833 QMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQ-KQWQEEEMWKE 891
+ +LK ER + + Y+ E+ K L++++ + Q++ K ++ + E
Sbjct: 1835 KRGAEALKGAHKYERKVKEMTYQAE----EDHKNILRLQDLVDKLQAKVKSYKRQAEEAE 1890
Query: 892 EQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRL-----EEGTQKMK 933
EQ + + + + + E ++ +S + +L + G+QKM+
Sbjct: 1891 EQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKME 1937
Score = 33.9 bits (76), Expect = 1.9
Identities = 37/188 (19%), Positives = 84/188 (44%), Gaps = 19/188 (10%)
Query: 870 MKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEEL------PKSSLQ 923
+K + E++ ++ E KEE ++ ++ E EEK QE+ +L +L
Sbjct: 844 LKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLM 903
Query: 924 RLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPH---RRREKGKEKQKPERGLEDLER 980
EE + + +LLE + ++ + +E + + ++R + +R ++DLE
Sbjct: 904 DAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLEL 963
Query: 981 QI-KTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENL 1039
+ K + + E + K L + + +S K K +Q +++ +TL++L
Sbjct: 964 TLTKVEKEKHATENKVKNLSEEMTALEENISKLTKE-KKSLQEAHQ--------QTLDDL 1014
Query: 1040 PDEKEPIS 1047
E++ ++
Sbjct: 1015 QVEEDKVN 1022
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 83.6 bits (205), Expect = 2e-15
Identities = 98/450 (21%), Positives = 199/450 (44%), Gaps = 72/450 (16%)
Query: 576 KEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQ-- 633
K+ +GE R L+ L K G+ S T K++ EELTK+
Sbjct: 142 KQLEGEARDLISRLH----------DSWKFAGELEQALSAVATQKKKADRYIEELTKERD 191
Query: 634 -----------------VKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAI 676
K+ +L + L V E SE ++ K E++ L Q+ +
Sbjct: 192 ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQL 251
Query: 677 MAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKY 736
A + D++GK + + ++ E E + + EE + E + + R+
Sbjct: 252 QA----EADHLGKELQSVSAKLQAQV---EENELWNRLNQQQEEKMWRQEEKIQE--REE 302
Query: 737 KDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMIL 796
K ++EE++ E+ K ++ M ++K + E +M+
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMM----WEKEEKMRRQE------------------EMMW 340
Query: 797 AEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEK 856
+ E R++ Q+ +E+E++RQE+ ++ +EQ + ++ + ++E EK
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEE--EKIREQEKRQEQEAKMWRQEEKIREQEEK 398
Query: 857 ISENWEEKKAWLQMKEGKQEQQSQKQW-QEEEMWKEEQKQATPKQAEQEEKQKQRGQEE- 914
I E E +Q +E K +Q +K W QEEEM ++E+K ++ +E+++K R QEE
Sbjct: 399 IREQEE----MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Query: 915 ----EELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQK 970
EE+ + +++ E KM Q ++++ +MR+ +++ + R ++ K +++
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514
Query: 971 PERGLEDLERQIKTKDQMQMKETQPKELEK 1000
E E E+ + +++M +E + +E E+
Sbjct: 515 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544
Score = 77.8 bits (190), Expect = 1e-13
Identities = 95/463 (20%), Positives = 213/463 (46%), Gaps = 40/463 (8%)
Query: 608 KKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSE-Q 666
KK I++GT +Q SHQ ++L R + ++ R+L K+E Q
Sbjct: 74 KKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQ--KTELQ 131
Query: 667 SNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVA 726
L Q A+ + D I + D E E A A + K K + Y +++
Sbjct: 132 MALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQ----KKKADRYIEELT 187
Query: 727 ETVTKI-LRKYKDTKKEEQVGEKPIKQKKVVSFMPG----LHFQKSPISAKSESSTLL-- 779
+ + L Y++T +E++ EK K ++ + + + + K E + LL
Sbjct: 188 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 247
Query: 780 --SYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGM 837
++ + +Q + A+++++ + + +E++ RQE+ +QE +E++
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307
Query: 838 SLK-----QQLLGERNLLKEHYEKISEN----WEEKKAWLQMKEGKQEQQSQKQWQEEEM 888
K +++ + ++ E EK+ WE+++ +++E EQ+ ++ QEE+
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE-QEEKR 366
Query: 889 WKEEQKQATPKQAEQEEK---QKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQ 945
+EE+ + K+ EQE K Q+++ +E+EE + + ++E +KM Q + ++ +
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 946 MRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQT 1005
M++ +++ + R+ EK +E++K R E+ R+ ++ MQ +E + E E + +
Sbjct: 427 MQEQEEKMR-----RQEEKIREQEKKIREQEEKIRE--QEEMMQEQEEKMGEQEGKMCEQ 479
Query: 1006 PMTLSPRWKSVLKDVQRSYEG----KEFQRNLKTLENLPDEKE 1044
+ + + + + ++ E +E + ++ E + E+E
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 522
Score = 71.6 bits (174), Expect = 8e-12
Identities = 94/456 (20%), Positives = 201/456 (44%), Gaps = 23/456 (5%)
Query: 486 SEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLE 545
+E + + YY +K+ E + S A +L+ +Q K+ + L
Sbjct: 128 TELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELT 187
Query: 546 QFR-----KVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSM-IQFDDTAE 599
+ R ++ R + D+ K++ + ++ E K EI+ V+ L ++
Sbjct: 188 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE-KSEIQLNVKELKRKLERAKLLL 246
Query: 600 PQKGKIKGKKHHISSG--TITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVL 657
PQ+ +++ + H+ ++++K + E+ EL ++ Q K + K ++
Sbjct: 247 PQQ-QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQ 305
Query: 658 ESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAK 717
E + EQ QE +M ++K+ + +K E K E EK+ + K
Sbjct: 306 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 365
Query: 718 MEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESST 777
+E +K+ E + ++ K ++EE++ E+ K ++ M Q+ + + E
Sbjct: 366 RQEE-EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE---QEEKMGEQEEKM- 420
Query: 778 LLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGM 837
+E + + +M E + + ++ +E+E+ QEQ + G+++
Sbjct: 421 ---WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMC 477
Query: 838 SLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQAT 897
+ ++ + ++ EKI E +EKK + +E +EQ+ Q QEE+MW++E+K
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIRE--QEKKI-REQEEKIREQEEMMQEQEEKMWEQEEKMCE 534
Query: 898 PKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMK 933
++ QE+++K R QEE+ + RL + +KM+
Sbjct: 535 QEEKMQEQEEKMRRQEEK--MREQEVRLRQQEEKMQ 568
Score = 70.9 bits (172), Expect = 1e-11
Identities = 78/372 (20%), Positives = 180/372 (48%), Gaps = 32/372 (8%)
Query: 609 KHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSN 668
++ I+ + K K +EK +L + KS ++ ++ + ++ + +L ++E +
Sbjct: 199 RNTITDEELKEKNAKLQEKLQLVESEKS-EIQLNVKELKRKLERAKLLLPQQQLQAEADH 257
Query: 669 LEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAET 728
L + +++ A L+ +++ + +++ +EE++ + + EK+ + K++E +K+ E
Sbjct: 258 LGKELQSVSAKLQAQVEE-NELWNRLNQQQEEKMWR--QEEKIQEREEKIQEQEEKIREQ 314
Query: 729 VTKILRKY--------KDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLS 780
K+ R+ K ++EE + EK K +++ M + + E +
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
Query: 781 YESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQ---EGQEQMSGM 837
E + + E E I + ++ +EK +++E+ + E QEQ M
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 838 SLKQQLLGERNL-LKEHYEKISENWE---EKKAWLQMKEGKQ-EQQSQKQWQEEEMWKEE 892
+++ + E+ ++E EKI E E E++ + +EGK EQ+++ Q QEE+M ++E
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494
Query: 893 QK---------QATPKQAEQEE---KQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLE 940
+K + K EQEE +Q+++ E+EE ++++E +KM+ Q +
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Query: 941 KENGQMRQIQKE 952
++ ++RQ +++
Sbjct: 555 EQEVRLRQQEEK 566
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 82.4 bits (202), Expect = 5e-15
Identities = 102/499 (20%), Positives = 226/499 (45%), Gaps = 77/499 (15%)
Query: 506 MKSFSEDKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEI 565
M + ++ K ++ L L ET+ KS + +++KR+ DK P E
Sbjct: 1 MPRITNEELKEKNAELQEELQLVETE----KSEIQL----HIKELKRKLETDKIPLPQEG 52
Query: 566 KVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHI--SSGTITSKEEK 623
+V E +E +G++R + + + + Q+G+++ ++ + G + +E +
Sbjct: 53 QVREQ-EGQVREQEGQVRE--QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 109
Query: 624 TEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQK 683
E+E ++ + V+ +E R E + ++ + E + + Q
Sbjct: 110 VREQEGQVREQEGQ--VREQEGQVREQEGQVREQEG-QVREQEGQVREQEGQVREQEGQV 166
Query: 684 IDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEE 743
+ G+ +++ +E+E R + ++G + +M E +++ E ++ K+EE
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQM------QKQEE 220
Query: 744 QVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESER 803
Q+GE+ + +K Q+ + + E +Q +++ +
Sbjct: 221 QMGEQEEQMRK----------QEEQMGEQEEQ----------------VQKQEEQVQKQE 254
Query: 804 DIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEE 863
+ Q +E++ + QE+ ++E +EQM LKQ KE E+ + E+
Sbjct: 255 E-------QMRKQEEQMREQEEQMREQEEQM----LKQ---------KEQTEQEEQTGEQ 294
Query: 864 KKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQ 923
++ + +E +EQ+ Q + QEE+M EQ++ KQ EQ +QK++ E++E +
Sbjct: 295 EEQMREQEEQMREQEEQMREQEEQM--REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Query: 924 RLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIK 983
++ E ++M+ Q + K+ QMR+ +++ R++E+ KQ+ + G E E+ +
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQM------RKQEEQMRKQEEQMG-EQKEQMGE 405
Query: 984 TKDQMQMKETQPKELEKMV 1002
K+QM+ +E Q E ++ +
Sbjct: 406 QKEQMREQEEQMGEQKEQM 424
Score = 77.8 bits (190), Expect = 1e-13
Identities = 59/238 (24%), Positives = 130/238 (54%), Gaps = 13/238 (5%)
Query: 812 QKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMK 871
Q +E++ Q+QE+ + E +EQM ++Q+ + +++ E++ + E+ + + +
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQ--EEQMGEQEEQVQKQEEQVQKQEEQMR---KQE 261
Query: 872 EGKQEQQSQKQWQEEEMWKE----EQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEE 927
E +EQ+ Q + QEE+M K+ EQ++ T +Q EQ +Q+++ +E+EE + +++ E
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 928 GTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQI-KTKD 986
++M Q + ++ QM + QKE + E+ ++ QK E + E Q+ K ++
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWE-QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEE 380
Query: 987 QMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKE 1044
QM+ +E Q ++ E+ + + + + + + + ++ E KE R K E++ ++KE
Sbjct: 381 QMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMR--KQEEHMGEQKE 436
Score = 68.6 bits (166), Expect = 7e-11
Identities = 56/223 (25%), Positives = 117/223 (52%), Gaps = 12/223 (5%)
Query: 816 KEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQ 875
+E+E Q +EQ Q G EQ M +++ +GE+ + E+ EE+ + + G+Q
Sbjct: 181 REQEGQVREQEGQMG-EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQ 239
Query: 876 EQQSQKQW-----QEEEMWKEE-----QKQATPKQAEQEEKQKQRGQEEEELPKSSLQRL 925
E+Q QKQ QEE+M K+E Q++ +Q EQ KQK++ ++EE+ + +++
Sbjct: 240 EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE-EQM 298
Query: 926 EEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTK 985
E ++M+ Q + ++ QMR+ +++ +K + ++ E+ + E+ + +
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358
Query: 986 DQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKE 1028
+QMQ +E Q ++ E+ + + + + + + K ++ E KE
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
Score = 57.8 bits (138), Expect = 1e-07
Identities = 59/303 (19%), Positives = 141/303 (46%), Gaps = 24/303 (7%)
Query: 703 LKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGL 762
+ R E+L A+++E Q V ++I K+ K++ + + P+ Q+ V G
Sbjct: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEG- 59
Query: 763 HFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQR 822
++ + + + E Q+ E + V + +E+E Q
Sbjct: 60 QVREQEGQVREQEGQVREQEG---------QVREQEGQVREQEGQVREQEGQVREQEGQV 110
Query: 823 QEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQ 882
+EQ Q +++ + Q+ + ++E ++ E++ ++ +EG+ +Q +
Sbjct: 111 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQV----REQEGQVREQEGQVREQEGQV 166
Query: 883 WQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKE 942
++E +E++ Q ++ + E++ Q G++E ++ + Q E+ Q K + + E+E
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE 226
Query: 943 NGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQI-KTKDQMQMKETQPKELEKM 1001
Q++K+ + +G E+ ++ QK E ++ E Q+ K ++QM+ +E Q +E E+
Sbjct: 227 E----QMRKQEEQMG-----EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQ 277
Query: 1002 VIQ 1004
+++
Sbjct: 278 MLK 280
Score = 54.7 bits (130), Expect = 1e-06
Identities = 46/240 (19%), Positives = 124/240 (51%), Gaps = 16/240 (6%)
Query: 816 KEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENW---EEKKAWLQMKE 872
+E+E Q +EQ Q +++ + Q+ + ++E ++ E E++ ++ +E
Sbjct: 76 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 135
Query: 873 GKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKM 932
G+ +Q + ++E +E++ Q ++ + E++ Q ++E ++ + Q E+ Q
Sbjct: 136 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMG 195
Query: 933 KTQGLLLEKENG---QMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQI-KTKDQM 988
+ +G + E+E Q Q+QK+ + +G E+ ++ +K E + + E Q+ K ++Q+
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMG-----EQEEQMRKQEEQMGEQEEQVQKQEEQV 250
Query: 989 QMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYE----GKEFQRNLKTLENLPDEKE 1044
Q +E Q ++ E+ + + + + + +LK +++ + G++ ++ + E + +++E
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310
Score = 53.5 bits (127), Expect = 2e-06
Identities = 51/254 (20%), Positives = 128/254 (50%), Gaps = 15/254 (5%)
Query: 792 IQMILAEIESERDIPTVSTVQKDH-KEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLL 850
IQ+ + E++ + + + Q+ +E+E Q +EQ EGQ + +++Q +
Sbjct: 30 IQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ---EGQVREQEGQVREQ----EGQV 82
Query: 851 KEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQR 910
+E ++ E++ ++ +EG+ +Q + ++E +E++ Q ++ + E++ Q
Sbjct: 83 REQEGQV----REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 138
Query: 911 GQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQK 970
++E ++ + Q E+ Q + +G + E+E GQ+R+ + + + R ++G+ ++
Sbjct: 139 REQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQVREQEGQVREQEGQMGEQ 197
Query: 971 PERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQ 1030
+ E E+ + ++QMQ +E Q E E+ + + + + + V K ++ + +E
Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257
Query: 1031 RNLKTLENLPDEKE 1044
R K E + +++E
Sbjct: 258 R--KQEEQMREQEE 269
Score = 47.0 bits (110), Expect = 2e-04
Identities = 60/343 (17%), Positives = 154/343 (44%), Gaps = 56/343 (16%)
Query: 576 KEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHI--SSGTITSKEEKTEEKEELTKQ 633
+E +G++R + + + + Q+G+++ ++ + G + +E + E+E ++
Sbjct: 132 REQEGQVRE--QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Query: 634 VKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDK 693
+ Q+ + ++ ++ + E + EQ +E Q ++++ + +G+ +
Sbjct: 190 QEG-QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQ------MRKQEEQMGE--QE 240
Query: 694 KTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQK 753
+ V K+EE +++ E E++ + +M E +++ E ++L++ + T++EEQ GE+ + +
Sbjct: 241 EQVQKQEEQVQKQE-EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
Query: 754 KVVSFM-----------PGLHFQKSPISAKSES---STLLSYESTDPVINNLIQMILAEI 799
+ M + Q+ + + E +E + + QM E
Sbjct: 300 EQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEE 359
Query: 800 ESERDIPTVSTVQKDHKEKEKQ--RQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKI 857
+ ++ V ++ +++E+Q +QE+ +++ +EQM
Sbjct: 360 QMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG---------------------- 397
Query: 858 SENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQ 900
E+K+ + KE +EQ+ Q Q+E+M K+E+ K+
Sbjct: 398 ----EQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 82.0 bits (201), Expect = 6e-15
Identities = 178/824 (21%), Positives = 326/824 (39%), Gaps = 133/824 (16%)
Query: 291 AHETSEAE-KELSLKIIRDLSNENEML------QQKLQDAEEKCEQLIRSKIVIEQLYAK 343
A E SEA KEL K++ L +N++ Q L DAEE+C+QLI++KI QL AK
Sbjct: 862 ALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKI---QLEAK 918
Query: 344 LSTSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNI------LDKELENIVDEVQRKETKDS 397
+ + + L ++ K ED + L+ L + E E K
Sbjct: 919 VKEMN--ERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 398 GIK-----WDSTISYTAQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDET 452
+ D I+ + ++ L E QQ A +D+ + K N +L K E +
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKA--LQEAHQQ--ALDDLQAEEDKVN-TLTKAKVKLEQQV 1031
Query: 453 DEYQSWKRSHKKATYVYETSGPNLSDN------------KSGQKVSEAKPSQYYELQV-- 498
D+ + KK E + L + Q++ E + +EL
Sbjct: 1032 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
Query: 499 ------------LKKKRKEMKSFSED---------KSKSPTEAKRKHLS--LTETKSQGG 535
L+KK KE+++ E+ +++ E R LS L E +
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1151
Query: 536 KSGTSMMMLEQFRKVKRESPFDKRP---TAAEIKVEPTTESLDKEGKGEIRSLVEPLSMI 592
++G + + + K KRE+ F K A ++ E T +L K+ + L E + +
Sbjct: 1152 EAGGATSVQIEMNK-KREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 593 Q-FDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKS--HQLVKSLSRVAKE 649
Q E +K + K + ++S + E+ + K L K ++ Q+ + S+ A+E
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTS----NMEQIIKAKANLEKMCRTLEDQMNEHRSK-AEE 1265
Query: 650 TSESTRVLESPDGKSEQSN------LEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELL 703
T S L S K + N L+E + I + K+ + D K +EE
Sbjct: 1266 TQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKA 1325
Query: 704 KRAEAEKLGI-----------------IKAKMEEYFQKVAETVTKILRKYKDTKKEEQVG 746
K A A L KA+++ K V + KY +T ++
Sbjct: 1326 KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY-ETDAIQRTE 1384
Query: 747 EKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIP 806
E +KK+ Q++ + ++ ++ S E T + N I+ ++ ++E
Sbjct: 1385 ELEEAKKKLAQ-----RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1439
Query: 807 TVSTVQKDHKEKEKQRQEQYLQEGQ-----EQMSGMSLKQQLLGERNLLKEHYEKI---- 857
++ + +K +Q +E Q Q SL +L +N +E E +
Sbjct: 1440 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1499
Query: 858 --SENWEEKKAWLQMKEGK------QEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQ 909
++N +E+ + L + G + ++ +KQ + E+M + + E EE +
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKIL 1559
Query: 910 RGQEEEELPKSSLQR-LEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLG--PHRRREKGK 966
R Q E K+ ++R L E ++M+ + + +R + L R E +
Sbjct: 1560 RAQLEFNQIKAEIERKLAEKDEEME------QAKRNHLRVVDSLQTSLDAETRSRNEALR 1613
Query: 967 EKQKPERGLEDLERQIKTKDQMQMK-ETQPKELEKMVIQTPMTL 1009
K+K E L ++E Q+ ++M + + Q K L+ ++ T + L
Sbjct: 1614 VKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1657
Score = 32.7 bits (73), Expect = 4.3
Identities = 31/154 (20%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 859 ENWEEKKAWLQ----MKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEE 914
+NW K + + +K ++E++ +E KE +++ ++ E EEK QE+
Sbjct: 825 KNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEK 884
Query: 915 EEL------PKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPH---RRREKG 965
+L + +L EE ++ + LE + +M + ++ + + ++R+
Sbjct: 885 NDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 944
Query: 966 KEKQKPERGLEDLERQI-KTKDQMQMKETQPKEL 998
E + +R ++DLE + K + + E + K L
Sbjct: 945 DECSELKRDIDDLELTLAKVEKEKHATENKVKNL 978
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens]
Length = 1116
Score = 81.6 bits (200), Expect = 8e-15
Identities = 163/785 (20%), Positives = 347/785 (44%), Gaps = 79/785 (10%)
Query: 302 SLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTS-STLKVLPGPSPQS 360
SL+ RD N LQ +L++ + L+R + +++ +KLS+S +++K P +
Sbjct: 142 SLRQARD--NTIMDLQTQLKEVLRE-NDLLRKDVEVKE--SKLSSSMNSIKTFWSPELKK 196
Query: 361 SRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTPDLTEL 420
RA+ K E + I ++ + +E Q + ++ + I DL +L
Sbjct: 197 ERALRK---DEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR--------DLNQL 245
Query: 421 RQQPVAS---EDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLS 477
QQ +S E + T++N + E + E +++ ++ ET L
Sbjct: 246 FQQDSSSRTGEPCVAELTEENFQRLHAE--HERQAKELFLLRKTLEEMELRIETQKQTL- 302
Query: 478 DNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRK-HLSLTETKSQGGK 536
N + + + L++L+ K K+ ED ++ A+ + H+ E+ + +
Sbjct: 303 -NARDESIKKL-------LEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKE 354
Query: 537 SGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDD 596
SM+ E R+ + +P + A + +E + +G +R L E + M++ +
Sbjct: 355 KENSMLREEMHRRFEN-APDSAKTKALQTVIEMKDSKISSMERG-LRDLEEEIQMLKSNG 412
Query: 597 TAEPQKGKIKGKKHHISSGTITSKEEKTEE-KEELT-KQVKSHQLVKSLSRVAKETSEST 654
++ + + K+ + + K E+ KEEL+ K+ + +L K + + E +
Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVK 472
Query: 655 RVLESPDGK--SEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKT-----VPKEEELLKRAE 707
+ L D + + Q+ LE + KQ I+ + ++ K + E + L+
Sbjct: 473 QELSRKDTELLALQTKLETLTNQF-SDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 531
Query: 708 AEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIK--QKKVVSFMPGLHFQ 765
EK ++ K ++ Q +AE + D K V E+ + QKK+ + L +
Sbjct: 532 EEKETMLNKKTKQ-IQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 590
Query: 766 KSPISAKSESSTLLSYEST--DPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQ 823
+ +S+ E L ++T D + L + + E ER I + Q+D E+EKQ +
Sbjct: 591 EKQMSSLKERVKSLQADTTNTDTALTTLEEALA---EKERTIERLKE-QRDRDEREKQEE 646
Query: 824 -EQYLQEGQEQMSGMSLKQQLLGERNL----LKEHYEKISENWEEKKAWLQMKEGKQEQQ 878
+ Y ++ ++ +SL Q L E+ LKEH ++ + +K + L+ E EQ+
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 706
Query: 879 SQKQWQEEEMWKEEQKQATPKQAEQE--------EKQKQRGQEEEELPKSSLQRLEEGTQ 930
++ + E K+ + A +A E E++ R ++E ++ + RL E +
Sbjct: 707 KEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 931 KMKTQGLLLEKENGQM-RQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQ-------- 981
+++ + +K+ ++ RQ++ + K + + +E+ EK+K + LE+ R+
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQ-VEKKKSAQMLEEARRREDNLNDSS 825
Query: 982 IKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVL--KDVQRSYEGKEFQRNLKTLENL 1039
+ +D ++ K+ + +ELE+ + ++ + R + VL ++ R+ K+ + L +E +
Sbjct: 826 QQLQDSLRKKDDRIEELEEALRESVQITAER-EMVLAQEESARTNAEKQVEELLMAMEKV 884
Query: 1040 PDEKE 1044
E E
Sbjct: 885 KQELE 889
Score = 55.5 bits (132), Expect = 6e-07
Identities = 160/881 (18%), Positives = 356/881 (40%), Gaps = 150/881 (17%)
Query: 121 EIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKILSRFS 180
+ R+ T+ ++ L+E VL E L+ D +E+ L + N++K F
Sbjct: 145 QARDNTIMDLQTQLKE---VLRENDLLRKD--------VEVKESKLSSSMNSIKT---FW 190
Query: 181 TSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVSEI-QG 239
+ L +++ +K S+ T+WK + RV++ + + Q + D+L ++++ Q
Sbjct: 191 SPELKKERALRKDEASKITIWKE-QYRVVQEENQHMQMTI-QALQDELRIQRDLNQLFQQ 248
Query: 240 MLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETSEAEK 299
G + L + + + + L +L L+ + + T +T A
Sbjct: 249 DSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIET--QKQTLNARD 306
Query: 300 ELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTLKVL------ 353
E S+K + ++ + + ++ E+ +L +++ + L + L +
Sbjct: 307 E-SIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMH 365
Query: 354 ----PGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTA 409
P ++A+ V + +D+ + +++ L ++ +E+Q +K + +S
Sbjct: 366 RRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQM-------LKSNGALS--- 415
Query: 410 QAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVY 469
TE R++ + ++ +K K + +E+ + + W+ KKA +
Sbjct: 416 --------TEEREEEMKQMEVYRSHSK--FMKNKVEQLKEELSSKEAQWEELKKKAAGLQ 465
Query: 470 ETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTE 529
G +V + + EL L+ K + + + D SK E ++ L+ E
Sbjct: 466 AEIG----------QVKQELSRKDTELLALQTKLETLTNQFSD-SKQHIEVLKESLTAKE 514
Query: 530 TKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGK--GEIRSLVE 587
++ ++ + L +++ T K + + +++G GEI L +
Sbjct: 515 QRAAILQTEVDALRLR----------LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKD 564
Query: 588 PLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVA 647
L +K +K ++ I + +E+ +KE+ +K VKSL
Sbjct: 565 MLD--------------VKERKVNVLQKKIENLQEQLRDKEKQMSSLKER--VKSLQADT 608
Query: 648 KETSESTRVLESPDGKSEQS--NLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKR 705
T + LE + E++ L+E ++ +++IDN K D K + ++ LL+
Sbjct: 609 TNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKK--DLKDLKEKVSLLQG 666
Query: 706 AEAEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQ 765
+EK + ++E+ +A + K KD++ + E ++QKK +
Sbjct: 667 DLSEKEASL-LDLKEHASSLASSGLK-----KDSRLKTL--EIALEQKKEECLKMESQLK 718
Query: 766 KSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHK-------EK 818
K+ +A ++ P +++ IQ + EI +D + + + D E
Sbjct: 719 KAHEAALEARAS--------PEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVEN 770
Query: 819 EKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQE-- 876
EK +++ + E + Q+ + K L +H E++ E+KK+ ++E ++
Sbjct: 771 EKNDKDKKIAELERQVKDQNKKVANL-------KHKEQV----EKKKSAQMLEEARRRED 819
Query: 877 ------QQSQKQWQEEEMWKEEQKQATPKQAE----------QEEKQKQRGQEEEELPKS 920
QQ Q ++++ EE ++A + + QEE + +++ E
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 879
Query: 921 SLQRLEEGTQKMK-----TQGLLLEKENGQMRQIQKEAKHL 956
+++++++ + MK TQ L EKE + KHL
Sbjct: 880 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHL 920
Score = 54.7 bits (130), Expect = 1e-06
Identities = 166/893 (18%), Positives = 356/893 (39%), Gaps = 131/893 (14%)
Query: 100 EHKKKQRTNFLEK---------MATYAKTIEIREKTLANILAWLEEWNDVLSEMTLMDVD 150
EH+++ + FL + + T +T+ R++++ +L L+ LS +
Sbjct: 273 EHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG--LSAKATEEDH 330
Query: 151 EHHHWIAQMELLPDTLKAI-----ENNVKILSRFSTSFLDEKKKQKKKILSRGTLWKSWK 205
E +A+ E+ L+++ + N + F + K K L K K
Sbjct: 331 ERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSK 390
Query: 206 ERVIKRPSTARALRPD-QMISDQLATNTKVSEIQGMLQELIGTTMFSTLENNAIKYISST 264
++R R L + QM+ A +T+ E + E+ + K++ +
Sbjct: 391 ISSMERG--LRDLEEEIQMLKSNGALSTEEREEEMKQMEVY---------RSHSKFMKNK 439
Query: 265 IVNLSTALSMLNDELKCVNFQSSTVYAHETSEAEKELSLKI--IRDLSNENEMLQQKLQD 322
+ L LS + + + +++ + A E + ++ELS K + L + E L + D
Sbjct: 440 VEQLKEELSSKEAQWEELKKKAAGLQA-EIGQVKQELSRKDTELLALQTKLETLTNQFSD 498
Query: 323 AEEKCEQLIRSKIVIEQLYAKLST----------------SSTLKVLPGPSPQSSRAIIK 366
+++ E L S EQ A L T + K + + + +
Sbjct: 499 SKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGE 558
Query: 367 VGDTEDNMD------NILDKELENIVDEVQRKETKDSGIKWDSTISYTAQAERTPDLTEL 420
+ D +D +D N+L K++EN+ ++++ KE + S +K + S A T
Sbjct: 559 IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLK-ERVKSLQADTTNTDTALTT 617
Query: 421 RQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYETSGPNLSDNK 480
++ +A ++ + + K+ + D + ++ +E ++K+ K +LS+ +
Sbjct: 618 LEEALAEKERTIERLKE-----QRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKE 672
Query: 481 SG-----QKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTETKSQGG 535
+ + S S + LK ++ E+ K ++ K+ H + E ++
Sbjct: 673 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPE 732
Query: 536 KSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFD 595
S + + + K ES + A+ +V+ E L KE + E + + + +
Sbjct: 733 MSDRIQHLEREITRYKDES------SKAQAEVDRLLEIL-KEVENEKND--KDKKIAELE 783
Query: 596 DTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTR 655
+ Q K+ KH +E+ E+K KS Q+++ R ++S++
Sbjct: 784 RQVKDQNKKVANLKH----------KEQVEKK-------KSAQMLEEARRREDNLNDSSQ 826
Query: 656 VLESPDGKSEQSNLEEFQEAIMAFLKQKIDN---IGKAFDKKTVPKE--EELLKRAE--A 708
L+ K + +EE +EA+ ++ + + + +T ++ EELL E
Sbjct: 827 QLQDSLRKKD-DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVK 885
Query: 709 EKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKE-EQVGEKPIKQKKVVSFMPGLHFQKS 767
++L +KAK+ Q +AE T + + +K E+V E +KQ+ ++ +
Sbjct: 886 QELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLE--MKQEALL----------A 933
Query: 768 PISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDHKEKEKQRQEQYL 827
IS K + LL S+ Q +A ++ E+D V +++ + + K + Y
Sbjct: 934 AISEKDANIALLELSSS----KKKTQEEVAALKREKD-RLVQQLKQQTQNRMKLMADNY- 987
Query: 828 QEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWL------------QMKEGKQ 875
E S S + + + + ++ +N + K ++ + G
Sbjct: 988 -EDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRGLT 1046
Query: 876 EQQSQKQWQEEEMWKEEQKQATPKQAEQE-EKQKQRGQEEEELPKSSLQRLEE 927
S ++ W+ E ++ T Q + E EK ++ E +E + LQ++ +
Sbjct: 1047 PPASYNLDDDQAAWENELQKMTRGQLQDELEKGERDNAELQEFANAILQQIAD 1099
Score = 35.4 bits (80), Expect = 0.67
Identities = 80/404 (19%), Positives = 158/404 (39%), Gaps = 54/404 (13%)
Query: 700 EELLKRAEAEKLGIIKAKMEEYFQKVAETV-TKILR---KYKDTKKEEQVGEKPIKQKKV 755
E LL++ E E +++ +M F+ ++ TK L+ + KD+K E+ ++ +
Sbjct: 347 ESLLEQKEKEN-SMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSM--ERGLRDLEE 403
Query: 756 VSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTVSTVQKDH 815
M + S + E + Y S + N ++ + E+ S+ +
Sbjct: 404 EIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAG 463
Query: 816 KEKEKQRQEQYLQEGQEQMSGMSLK-QQLLGERNLLKEHYEKISENW---EEKKAWLQMK 871
+ E + +Q L ++ + K + L + + K+H E + E+ E++ A LQ +
Sbjct: 464 LQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTE 523
Query: 872 --------EGKQEQQSQKQWQEEEMWKEEQKQA-----------------TPKQAEQEEK 906
E K+ ++K Q ++M +E+ QA Q + E
Sbjct: 524 VDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENL 583
Query: 907 QKQRGQEEEELP--KSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREK 964
Q+Q +E+++ K ++ L+ T T LE+ + + + K REK
Sbjct: 584 QEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREK 643
Query: 965 GKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSY 1024
+E ++ L+DL K+++ + + E E ++ S S LK R
Sbjct: 644 QEEIDNYKKDLKDL------KEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSR-- 695
Query: 1025 EGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISGQP 1068
LKTLE ++K+ + L+ + AL P
Sbjct: 696 --------LKTLEIALEQKKEECLKMESQLKKAHEAALEARASP 731
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 81.3 bits (199), Expect = 1e-14
Identities = 207/1012 (20%), Positives = 411/1012 (40%), Gaps = 162/1012 (16%)
Query: 59 LHRAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSE---RNVSLTEHKKKQRTNFLEKMAT 115
L R++ +MQ E + + + R N E ++ LTE K + +
Sbjct: 845 LQVTRQEEEMQAKE--DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL 902
Query: 116 YAKTIEIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKI 175
YA+ E+R + A +E ++L EM A++E D + ++ K
Sbjct: 903 YAEAEEMRVRLAAK----KQELEEILHEME-----------ARLEEEEDRGQQLQAERKK 947
Query: 176 LSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVS 235
+++ L+E+ ++++ + L K E IK+ + DQ N K+S
Sbjct: 948 MAQQMLD-LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQ--------NNKLS 998
Query: 236 EIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETS 295
+ + +L+E I +L+T L+ +E K N + HE+
Sbjct: 999 KERKLLEERIS--------------------DLTTNLA--EEEEKAKNL-TKLKNKHESM 1035
Query: 296 EAEKELSLKIIRDLSNENEMLQQKLQ-DAEEKCEQLIRSKIVIEQLYAKLSTS-----ST 349
+E E+ LK E E L++KL+ DA + EQ+ + I +L +L+ +
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1095
Query: 350 LKVLPGPSPQSSRAIIKVGDTEDNMDNIL-DKELENIVDEVQRKETKDSGIKWDSTISYT 408
L L Q + A+ K+ + E ++ ++ D + E K+ +D G + ++
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL---K 1152
Query: 409 AQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYV 468
+ E T D T +Q+ A + V++ K +E + E Q + K A V
Sbjct: 1153 TELEDTLDSTATQQELRAKRE-------QEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 469 YETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSE--DKSKSPTEAKRKHLS 526
E + + ++ AK + Q L+K+ ++ ++K E K+K L
Sbjct: 1206 EELT-------EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 527 LTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLV 586
+ Q S E KV + + +VE T L+ E +G+ L
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHK----------LQNEVESVTGMLN-EAEGKAIKLA 1307
Query: 587 EPLSMI--QFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQ-LVKSL 643
+ ++ + Q DT E + + + +K ++S+ +EE+ +++L +++++ Q L + +
Sbjct: 1308 KDVASLSSQLQDTQELLQEETR-QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1366
Query: 644 SRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVP--KEEE 701
S + + S+S + L+ S +E +E F K+ I+N+ + +++K K E+
Sbjct: 1367 STLNIQLSDSKKKLQD-----FASTVEALEEGKKRFQKE-IENLTQQYEEKAAAYDKLEK 1420
Query: 702 LLKRAEAEKLGII-------------KAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748
R + E ++ + K ++ Q +AE I KY D +++ E
Sbjct: 1421 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE-KNISSKYAD-ERDRAEAEA 1478
Query: 749 PIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTV 808
K+ K +S L + + AK E E T N +++ + ++ S +D
Sbjct: 1479 REKETKALSLARAL---EEALEAKEE------LERT----NKMLKAEMEDLVSSKD---- 1521
Query: 809 STVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWL 868
V K+ E EK ++ L+ E+M K QL E E + E+ K L
Sbjct: 1522 -DVGKNVHELEKSKRA--LETQMEEM-----KTQL--------EELEDELQATEDAKLRL 1565
Query: 869 QMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEG 928
++ + Q ++ Q + EE+++ +Q + E + + +++ L ++ ++LE
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 929 TQKMKTQG-----------LLLEKENGQMRQIQKEAKHLGPHRRR--EKGKEKQKPERGL 975
+ ++ Q L K QM+ Q+E + R KE +K + L
Sbjct: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
Query: 976 EDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGK 1027
E Q++ + + +LEK + + S ++ L+D +R E +
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
Score = 57.0 bits (136), Expect = 2e-07
Identities = 139/719 (19%), Positives = 274/719 (38%), Gaps = 90/719 (12%)
Query: 231 NTKVSEIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVY 290
N KV ++Q ++ + G M + E AIK ++ + +LS+ L Q +
Sbjct: 1279 NDKVHKLQNEVESVTG--MLNEAEGKAIK-LAKDVASLSSQL------------QDTQEL 1323
Query: 291 AHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTL 350
E + + +S K+ R L E LQ +L + E + L R STL
Sbjct: 1324 LQEETRQKLNVSTKL-RQLEEERNSLQDQLDEEMEAKQNLERH-------------ISTL 1369
Query: 351 KVLPGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQ 410
+ S + + + + KE+EN+ + + K ++
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
Query: 411 AERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYE 470
+ DL RQ E + K DE D ++ R E
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK-------E 1482
Query: 471 TSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTET 530
T +L+ ++ ++ EAK ++LK + +++ S +D K+ E ++ +L ET
Sbjct: 1483 TKALSLA--RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL-ET 1539
Query: 531 KSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLS 590
+ + K+ + E + + A + + E ++ D++ + + R L L
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 591 MIQFD--------DTAEPQKGKIKGKKHHI---SSGTITSKEEKTEEKEELTKQVKSHQL 639
+ + A K K++G + + I +EE ++ +L Q+K Q
Sbjct: 1600 EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR 1659
Query: 640 VKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKE 699
+R +++ +T KS +++L + QE + A + + K D +
Sbjct: 1660 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR-----KQADLEKEELA 1714
Query: 700 EELLK--------RAEAEKLGIIKAKMEEYFQKVAETVTKIL-RKYKDTKKEEQVGEKPI 750
EEL + E +L A++EE ++ + + R K T++ EQ+ +
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
Query: 751 KQKKVV----SFMPGLHFQKSPISAK---SESSTLLSYESTDPVINNLIQMILAEIESER 803
++ S L Q + +K E + ++ST + I + ++E E
Sbjct: 1775 TERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA 1834
Query: 804 DIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEE 863
+T K K+K+K+ +E LQ E+ K+Q EK N
Sbjct: 1835 REKQAAT--KSLKQKDKKLKEILLQVEDERKMAEQYKEQA-----------EK--GNARV 1879
Query: 864 KKAWLQMKEGKQEQQ----SQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELP 918
K+ Q++E ++E Q ++++ Q E E +A ++ + + +RG E +P
Sbjct: 1880 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1938
Score = 53.1 bits (126), Expect = 3e-06
Identities = 138/688 (20%), Positives = 260/688 (37%), Gaps = 139/688 (20%)
Query: 58 QLHRAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYA 117
QL R + QL E M + + + N+ L++ KKK + +A
Sbjct: 1340 QLEEERNSLQDQLDEEMEAKQNLERHISTL-------NIQLSDSKKK--------LQDFA 1384
Query: 118 KTIEIREKTLANILAWLEEWNDVLSEMTLM-DVDEHHHWIAQMEL------LPDTLKAIE 170
T+E E+ +E E D E Q EL L + + +
Sbjct: 1385 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS 1444
Query: 171 NNVKILSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLAT 230
N K +F +EK K R +E+ K S ARAL ++L
Sbjct: 1445 NLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELER 1504
Query: 231 NTKVSEIQGMLQELIGTT-----MFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQ 285
K+ ++ +++L+ + LE + + + + + + T L L DEL+
Sbjct: 1505 TNKM--LKAEMEDLVSSKDDVGKNVHELEKSK-RALETQMEEMKTQLEELEDELQ----- 1556
Query: 286 SSTVYAHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLS 345
A E ++ E++++ ++ + LQ + + EEK QL R + + +L
Sbjct: 1557 -----ATEDAKLRLEVNMQALKGQFERD--LQARDEQNEEKRRQLQRQ---LHEYETELE 1606
Query: 346 TSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNILD------KELENIVDEVQ--RKETKDS 397
+ L + + +K D E D+ + K+L + +++ ++E +D+
Sbjct: 1607 DERKQRALAAAAKKKLEGDLK--DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 398 GIKWDSTISYTAQAERTP-----DLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDET 452
D + + E+ DL +L++ A+E + K+ D +E+
Sbjct: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER----------ARKQADLEKEELA 1714
Query: 453 DEYQSWKRSHKKATYVYETSGPN-LSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSE 511
+E S SG N L D K + EA+ +Q E L++++ M++ S+
Sbjct: 1715 EELAS------------SLSGRNALQDEK---RRLEARIAQLEE--ELEEEQGNMEAMSD 1757
Query: 512 DKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLEQFRKVKR----------ESPFDKRPT 561
K+ +A++ L +S K+ ++ LE+ K R +S F
Sbjct: 1758 RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIA 1817
Query: 562 AAEIKVEPTTESLDKEG----------KGEIRSLVEPLSMI--------QFDDTAEPQKG 603
A E K+ E +++E K + + L E L + Q+ + AE
Sbjct: 1818 ALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA 1877
Query: 604 KIKGKKHHISSGTITSK-------------EEKTEEKEELTKQVKSHQLVKSLSRVAKET 650
++K K + S+ +E TE E + ++V + +KS R ET
Sbjct: 1878 RVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA---LKSKLRRGNET 1934
Query: 651 S-------ESTRVLESPDGKSEQSNLEE 671
S RV+E+ DG E+++ +
Sbjct: 1935 SFVPSRRSGGRRVIENADGSEEETDTRD 1962
Score = 45.8 bits (107), Expect = 5e-04
Identities = 59/260 (22%), Positives = 114/260 (43%), Gaps = 23/260 (8%)
Query: 795 ILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHY 854
+LA +E ERD+ + + + Q+Q++ M + Q RN Y
Sbjct: 774 VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQ-----RNCAA--Y 826
Query: 855 EKISENWEEKKAWLQMKE----GKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQR 910
K+ NW+ + + ++K +QE++ Q + E + KE Q++A + E E+K Q
Sbjct: 827 LKL-RNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885
Query: 911 GQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAK---HLGPHRRREKGKE 967
EE+ L + LQ E + + + L + ++ +I E + R ++ E
Sbjct: 886 -TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE 944
Query: 968 KQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQR--SYE 1025
++K + + DLE Q++ ++ + K +LEK+ + + V+ D S E
Sbjct: 945 RKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 1026 GKEFQRNLKTL-ENLPDEKE 1044
K + + L NL +E+E
Sbjct: 1001 RKLLEERISDLTTNLAEEEE 1020
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 81.3 bits (199), Expect = 1e-14
Identities = 207/1012 (20%), Positives = 411/1012 (40%), Gaps = 162/1012 (16%)
Query: 59 LHRAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSE---RNVSLTEHKKKQRTNFLEKMAT 115
L R++ +MQ E + + + R N E ++ LTE K + +
Sbjct: 852 LQVTRQEEEMQAKE--DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL 909
Query: 116 YAKTIEIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKI 175
YA+ E+R + A +E ++L EM A++E D + ++ K
Sbjct: 910 YAEAEEMRVRLAAK----KQELEEILHEME-----------ARLEEEEDRGQQLQAERKK 954
Query: 176 LSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVS 235
+++ L+E+ ++++ + L K E IK+ + DQ N K+S
Sbjct: 955 MAQQMLD-LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQ--------NNKLS 1005
Query: 236 EIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETS 295
+ + +L+E I +L+T L+ +E K N + HE+
Sbjct: 1006 KERKLLEERIS--------------------DLTTNLA--EEEEKAKNL-TKLKNKHESM 1042
Query: 296 EAEKELSLKIIRDLSNENEMLQQKLQ-DAEEKCEQLIRSKIVIEQLYAKLSTS-----ST 349
+E E+ LK E E L++KL+ DA + EQ+ + I +L +L+ +
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 350 LKVLPGPSPQSSRAIIKVGDTEDNMDNIL-DKELENIVDEVQRKETKDSGIKWDSTISYT 408
L L Q + A+ K+ + E ++ ++ D + E K+ +D G + ++
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL---K 1159
Query: 409 AQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYV 468
+ E T D T +Q+ A + V++ K +E + E Q + K A V
Sbjct: 1160 TELEDTLDSTATQQELRAKRE-------QEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 469 YETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSE--DKSKSPTEAKRKHLS 526
E + + ++ AK + Q L+K+ ++ ++K E K+K L
Sbjct: 1213 EELT-------EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 527 LTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLV 586
+ Q S E KV + + +VE T L+ E +G+ L
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHK----------LQNEVESVTGMLN-EAEGKAIKLA 1314
Query: 587 EPLSMI--QFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQ-LVKSL 643
+ ++ + Q DT E + + + +K ++S+ +EE+ +++L +++++ Q L + +
Sbjct: 1315 KDVASLSSQLQDTQELLQEETR-QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1373
Query: 644 SRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVP--KEEE 701
S + + S+S + L+ S +E +E F K+ I+N+ + +++K K E+
Sbjct: 1374 STLNIQLSDSKKKLQD-----FASTVEALEEGKKRFQKE-IENLTQQYEEKAAAYDKLEK 1427
Query: 702 LLKRAEAEKLGII-------------KAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748
R + E ++ + K ++ Q +AE I KY D +++ E
Sbjct: 1428 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE-KNISSKYAD-ERDRAEAEA 1485
Query: 749 PIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTV 808
K+ K +S L + + AK E E T N +++ + ++ S +D
Sbjct: 1486 REKETKALSLARAL---EEALEAKEE------LERT----NKMLKAEMEDLVSSKD---- 1528
Query: 809 STVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWL 868
V K+ E EK ++ L+ E+M K QL E E + E+ K L
Sbjct: 1529 -DVGKNVHELEKSKRA--LETQMEEM-----KTQL--------EELEDELQATEDAKLRL 1572
Query: 869 QMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEG 928
++ + Q ++ Q + EE+++ +Q + E + + +++ L ++ ++LE
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1632
Query: 929 TQKMKTQG-----------LLLEKENGQMRQIQKEAKHLGPHRRR--EKGKEKQKPERGL 975
+ ++ Q L K QM+ Q+E + R KE +K + L
Sbjct: 1633 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1692
Query: 976 EDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGK 1027
E Q++ + + +LEK + + S ++ L+D +R E +
Sbjct: 1693 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1744
Score = 57.0 bits (136), Expect = 2e-07
Identities = 139/719 (19%), Positives = 274/719 (38%), Gaps = 90/719 (12%)
Query: 231 NTKVSEIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVY 290
N KV ++Q ++ + G M + E AIK ++ + +LS+ L Q +
Sbjct: 1286 NDKVHKLQNEVESVTG--MLNEAEGKAIK-LAKDVASLSSQL------------QDTQEL 1330
Query: 291 AHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTL 350
E + + +S K+ R L E LQ +L + E + L R STL
Sbjct: 1331 LQEETRQKLNVSTKL-RQLEEERNSLQDQLDEEMEAKQNLERH-------------ISTL 1376
Query: 351 KVLPGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQ 410
+ S + + + + KE+EN+ + + K ++
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1436
Query: 411 AERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYE 470
+ DL RQ E + K DE D ++ R E
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK-------E 1489
Query: 471 TSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTET 530
T +L+ ++ ++ EAK ++LK + +++ S +D K+ E ++ +L ET
Sbjct: 1490 TKALSLA--RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL-ET 1546
Query: 531 KSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLS 590
+ + K+ + E + + A + + E ++ D++ + + R L L
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 591 MIQFD--------DTAEPQKGKIKGKKHHI---SSGTITSKEEKTEEKEELTKQVKSHQL 639
+ + A K K++G + + I +EE ++ +L Q+K Q
Sbjct: 1607 EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR 1666
Query: 640 VKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKE 699
+R +++ +T KS +++L + QE + A + + K D +
Sbjct: 1667 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR-----KQADLEKEELA 1721
Query: 700 EELLK--------RAEAEKLGIIKAKMEEYFQKVAETVTKIL-RKYKDTKKEEQVGEKPI 750
EEL + E +L A++EE ++ + + R K T++ EQ+ +
Sbjct: 1722 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1781
Query: 751 KQKKVV----SFMPGLHFQKSPISAK---SESSTLLSYESTDPVINNLIQMILAEIESER 803
++ S L Q + +K E + ++ST + I + ++E E
Sbjct: 1782 TERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA 1841
Query: 804 DIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEE 863
+T K K+K+K+ +E LQ E+ K+Q EK N
Sbjct: 1842 REKQAAT--KSLKQKDKKLKEILLQVEDERKMAEQYKEQA-----------EK--GNARV 1886
Query: 864 KKAWLQMKEGKQEQQ----SQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELP 918
K+ Q++E ++E Q ++++ Q E E +A ++ + + +RG E +P
Sbjct: 1887 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1945
Score = 53.1 bits (126), Expect = 3e-06
Identities = 138/688 (20%), Positives = 260/688 (37%), Gaps = 139/688 (20%)
Query: 58 QLHRAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYA 117
QL R + QL E M + + + N+ L++ KKK + +A
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTL-------NIQLSDSKKK--------LQDFA 1391
Query: 118 KTIEIREKTLANILAWLEEWNDVLSEMTLM-DVDEHHHWIAQMEL------LPDTLKAIE 170
T+E E+ +E E D E Q EL L + + +
Sbjct: 1392 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS 1451
Query: 171 NNVKILSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLAT 230
N K +F +EK K R +E+ K S ARAL ++L
Sbjct: 1452 NLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELER 1511
Query: 231 NTKVSEIQGMLQELIGTT-----MFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQ 285
K+ ++ +++L+ + LE + + + + + + T L L DEL+
Sbjct: 1512 TNKM--LKAEMEDLVSSKDDVGKNVHELEKSK-RALETQMEEMKTQLEELEDELQ----- 1563
Query: 286 SSTVYAHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLS 345
A E ++ E++++ ++ + LQ + + EEK QL R + + +L
Sbjct: 1564 -----ATEDAKLRLEVNMQALKGQFERD--LQARDEQNEEKRRQLQRQ---LHEYETELE 1613
Query: 346 TSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNILD------KELENIVDEVQ--RKETKDS 397
+ L + + +K D E D+ + K+L + +++ ++E +D+
Sbjct: 1614 DERKQRALAAAAKKKLEGDLK--DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 398 GIKWDSTISYTAQAERTP-----DLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDET 452
D + + E+ DL +L++ A+E + K+ D +E+
Sbjct: 1672 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER----------ARKQADLEKEELA 1721
Query: 453 DEYQSWKRSHKKATYVYETSGPN-LSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSE 511
+E S SG N L D K + EA+ +Q E L++++ M++ S+
Sbjct: 1722 EELAS------------SLSGRNALQDEK---RRLEARIAQLEE--ELEEEQGNMEAMSD 1764
Query: 512 DKSKSPTEAKRKHLSLTETKSQGGKSGTSMMMLEQFRKVKR----------ESPFDKRPT 561
K+ +A++ L +S K+ ++ LE+ K R +S F
Sbjct: 1765 RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIA 1824
Query: 562 AAEIKVEPTTESLDKEG----------KGEIRSLVEPLSMI--------QFDDTAEPQKG 603
A E K+ E +++E K + + L E L + Q+ + AE
Sbjct: 1825 ALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA 1884
Query: 604 KIKGKKHHISSGTITSK-------------EEKTEEKEELTKQVKSHQLVKSLSRVAKET 650
++K K + S+ +E TE E + ++V + +KS R ET
Sbjct: 1885 RVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA---LKSKLRRGNET 1941
Query: 651 S-------ESTRVLESPDGKSEQSNLEE 671
S RV+E+ DG E+++ +
Sbjct: 1942 SFVPSRRSGGRRVIENADGSEEETDTRD 1969
Score = 45.8 bits (107), Expect = 5e-04
Identities = 59/260 (22%), Positives = 114/260 (43%), Gaps = 23/260 (8%)
Query: 795 ILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHY 854
+LA +E ERD+ + + + Q+Q++ M + Q RN Y
Sbjct: 781 VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQ-----RNCAA--Y 833
Query: 855 EKISENWEEKKAWLQMKE----GKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQR 910
K+ NW+ + + ++K +QE++ Q + E + KE Q++A + E E+K Q
Sbjct: 834 LKL-RNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 892
Query: 911 GQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAK---HLGPHRRREKGKE 967
EE+ L + LQ E + + + L + ++ +I E + R ++ E
Sbjct: 893 -TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE 951
Query: 968 KQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQR--SYE 1025
++K + + DLE Q++ ++ + K +LEK+ + + V+ D S E
Sbjct: 952 RKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Query: 1026 GKEFQRNLKTL-ENLPDEKE 1044
K + + L NL +E+E
Sbjct: 1008 RKLLEERISDLTTNLAEEEE 1027
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 81.3 bits (199), Expect = 1e-14
Identities = 207/1012 (20%), Positives = 411/1012 (40%), Gaps = 162/1012 (16%)
Query: 59 LHRAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSE---RNVSLTEHKKKQRTNFLEKMAT 115
L R++ +MQ E + + + R N E ++ LTE K + +
Sbjct: 852 LQVTRQEEEMQAKE--DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL 909
Query: 116 YAKTIEIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKI 175
YA+ E+R + A +E ++L EM A++E D + ++ K
Sbjct: 910 YAEAEEMRVRLAAK----KQELEEILHEME-----------ARLEEEEDRGQQLQAERKK 954
Query: 176 LSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVS 235
+++ L+E+ ++++ + L K E IK+ + DQ N K+S
Sbjct: 955 MAQQMLD-LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQ--------NNKLS 1005
Query: 236 EIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETS 295
+ + +L+E I +L+T L+ +E K N + HE+
Sbjct: 1006 KERKLLEERIS--------------------DLTTNLA--EEEEKAKNL-TKLKNKHESM 1042
Query: 296 EAEKELSLKIIRDLSNENEMLQQKLQ-DAEEKCEQLIRSKIVIEQLYAKLSTS-----ST 349
+E E+ LK E E L++KL+ DA + EQ+ + I +L +L+ +
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 350 LKVLPGPSPQSSRAIIKVGDTEDNMDNIL-DKELENIVDEVQRKETKDSGIKWDSTISYT 408
L L Q + A+ K+ + E ++ ++ D + E K+ +D G + ++
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL---K 1159
Query: 409 AQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYV 468
+ E T D T +Q+ A + V++ K +E + E Q + K A V
Sbjct: 1160 TELEDTLDSTATQQELRAKRE-------QEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 469 YETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSE--DKSKSPTEAKRKHLS 526
E + + ++ AK + Q L+K+ ++ ++K E K+K L
Sbjct: 1213 EELT-------EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 527 LTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLV 586
+ Q S E KV + + +VE T L+ E +G+ L
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHK----------LQNEVESVTGMLN-EAEGKAIKLA 1314
Query: 587 EPLSMI--QFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQ-LVKSL 643
+ ++ + Q DT E + + + +K ++S+ +EE+ +++L +++++ Q L + +
Sbjct: 1315 KDVASLSSQLQDTQELLQEETR-QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1373
Query: 644 SRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVP--KEEE 701
S + + S+S + L+ S +E +E F K+ I+N+ + +++K K E+
Sbjct: 1374 STLNIQLSDSKKKLQD-----FASTVEALEEGKKRFQKE-IENLTQQYEEKAAAYDKLEK 1427
Query: 702 LLKRAEAEKLGII-------------KAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748
R + E ++ + K ++ Q +AE I KY D +++ E
Sbjct: 1428 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE-KNISSKYAD-ERDRAEAEA 1485
Query: 749 PIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTV 808
K+ K +S L + + AK E E T N +++ + ++ S +D
Sbjct: 1486 REKETKALSLARAL---EEALEAKEE------LERT----NKMLKAEMEDLVSSKD---- 1528
Query: 809 STVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWL 868
V K+ E EK ++ L+ E+M K QL E E + E+ K L
Sbjct: 1529 -DVGKNVHELEKSKRA--LETQMEEM-----KTQL--------EELEDELQATEDAKLRL 1572
Query: 869 QMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEG 928
++ + Q ++ Q + EE+++ +Q + E + + +++ L ++ ++LE
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1632
Query: 929 TQKMKTQG-----------LLLEKENGQMRQIQKEAKHLGPHRRR--EKGKEKQKPERGL 975
+ ++ Q L K QM+ Q+E + R KE +K + L
Sbjct: 1633 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1692
Query: 976 EDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGK 1027
E Q++ + + +LEK + + S ++ L+D +R E +
Sbjct: 1693 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1744
Score = 54.7 bits (130), Expect = 1e-06
Identities = 131/688 (19%), Positives = 259/688 (37%), Gaps = 73/688 (10%)
Query: 231 NTKVSEIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVY 290
N KV ++Q ++ + G M + E AIK ++ + +LS+ L Q +
Sbjct: 1286 NDKVHKLQNEVESVTG--MLNEAEGKAIK-LAKDVASLSSQL------------QDTQEL 1330
Query: 291 AHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTL 350
E + + +S K+ R L E LQ +L + E + L R STL
Sbjct: 1331 LQEETRQKLNVSTKL-RQLEEERNSLQDQLDEEMEAKQNLERH-------------ISTL 1376
Query: 351 KVLPGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQ 410
+ S + + + + KE+EN+ + + K ++
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1436
Query: 411 AERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYE 470
+ DL RQ E + K DE D ++ R E
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK-------E 1489
Query: 471 TSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTET 530
T +L+ ++ ++ EAK ++LK + +++ S +D K+ E ++ +L ET
Sbjct: 1490 TKALSLA--RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL-ET 1546
Query: 531 KSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLS 590
+ + K+ + E + + A + + E ++ D++ + + R L L
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 591 MIQFD--------DTAEPQKGKIKGKKHHI---SSGTITSKEEKTEEKEELTKQVKSHQL 639
+ + A K K++G + + I +EE ++ +L Q+K Q
Sbjct: 1607 EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR 1666
Query: 640 VKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKE 699
+R +++ +T KS +++L + QE + A + + K D +
Sbjct: 1667 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR-----KQADLEKEELA 1721
Query: 700 EELLK--------RAEAEKLGIIKAKMEEYFQKVAETVTKIL-RKYKDTKKEEQVGEKPI 750
EEL + E +L A++EE ++ + + R K T++ EQ+ +
Sbjct: 1722 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1781
Query: 751 KQKKVV----SFMPGLHFQKSPISAK---SESSTLLSYESTDPVINNLIQMILAEIESER 803
++ S L Q + +K E + ++ST + I + ++E E
Sbjct: 1782 TERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA 1841
Query: 804 DIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEE 863
+T K K+K+K+ +E LQ E+ K+Q +K+ ++ E EE
Sbjct: 1842 REKQAAT--KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE 1899
Query: 864 KKAWLQMKEGKQEQQSQKQWQEEEMWKE 891
+ + Q + + E M +E
Sbjct: 1900 SQRINANRRKLQRELDEATESNEAMGRE 1927
Score = 45.8 bits (107), Expect = 5e-04
Identities = 59/260 (22%), Positives = 114/260 (43%), Gaps = 23/260 (8%)
Query: 795 ILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHY 854
+LA +E ERD+ + + + Q+Q++ M + Q RN Y
Sbjct: 781 VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQ-----RNCAA--Y 833
Query: 855 EKISENWEEKKAWLQMKE----GKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQR 910
K+ NW+ + + ++K +QE++ Q + E + KE Q++A + E E+K Q
Sbjct: 834 LKL-RNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 892
Query: 911 GQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAK---HLGPHRRREKGKE 967
EE+ L + LQ E + + + L + ++ +I E + R ++ E
Sbjct: 893 -TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE 951
Query: 968 KQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQR--SYE 1025
++K + + DLE Q++ ++ + K +LEK+ + + V+ D S E
Sbjct: 952 RKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Query: 1026 GKEFQRNLKTL-ENLPDEKE 1044
K + + L NL +E+E
Sbjct: 1008 RKLLEERISDLTTNLAEEEE 1027
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 81.3 bits (199), Expect = 1e-14
Identities = 207/1012 (20%), Positives = 411/1012 (40%), Gaps = 162/1012 (16%)
Query: 59 LHRAREDIDMQLSEIMNNVHRIMTRYTLVFNSSSE---RNVSLTEHKKKQRTNFLEKMAT 115
L R++ +MQ E + + + R N E ++ LTE K + +
Sbjct: 845 LQVTRQEEEMQAKE--DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL 902
Query: 116 YAKTIEIREKTLANILAWLEEWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAIENNVKI 175
YA+ E+R + A +E ++L EM A++E D + ++ K
Sbjct: 903 YAEAEEMRVRLAAK----KQELEEILHEME-----------ARLEEEEDRGQQLQAERKK 947
Query: 176 LSRFSTSFLDEKKKQKKKILSRGTLWKSWKERVIKRPSTARALRPDQMISDQLATNTKVS 235
+++ L+E+ ++++ + L K E IK+ + DQ N K+S
Sbjct: 948 MAQQMLD-LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQ--------NNKLS 998
Query: 236 EIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVYAHETS 295
+ + +L+E I +L+T L+ +E K N + HE+
Sbjct: 999 KERKLLEERIS--------------------DLTTNLA--EEEEKAKNL-TKLKNKHESM 1035
Query: 296 EAEKELSLKIIRDLSNENEMLQQKLQ-DAEEKCEQLIRSKIVIEQLYAKLSTS-----ST 349
+E E+ LK E E L++KL+ DA + EQ+ + I +L +L+ +
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1095
Query: 350 LKVLPGPSPQSSRAIIKVGDTEDNMDNIL-DKELENIVDEVQRKETKDSGIKWDSTISYT 408
L L Q + A+ K+ + E ++ ++ D + E K+ +D G + ++
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL---K 1152
Query: 409 AQAERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYV 468
+ E T D T +Q+ A + V++ K +E + E Q + K A V
Sbjct: 1153 TELEDTLDSTATQQELRAKRE-------QEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 469 YETSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSE--DKSKSPTEAKRKHLS 526
E + + ++ AK + Q L+K+ ++ ++K E K+K L
Sbjct: 1206 EELT-------EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 527 LTETKSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLV 586
+ Q S E KV + + +VE T L+ E +G+ L
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHK----------LQNEVESVTGMLN-EAEGKAIKLA 1307
Query: 587 EPLSMI--QFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEKEELTKQVKSHQ-LVKSL 643
+ ++ + Q DT E + + + +K ++S+ +EE+ +++L +++++ Q L + +
Sbjct: 1308 KDVASLSSQLQDTQELLQEETR-QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1366
Query: 644 SRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVP--KEEE 701
S + + S+S + L+ S +E +E F K+ I+N+ + +++K K E+
Sbjct: 1367 STLNIQLSDSKKKLQD-----FASTVEALEEGKKRFQKE-IENLTQQYEEKAAAYDKLEK 1420
Query: 702 LLKRAEAEKLGII-------------KAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748
R + E ++ + K ++ Q +AE I KY D +++ E
Sbjct: 1421 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE-KNISSKYAD-ERDRAEAEA 1478
Query: 749 PIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYESTDPVINNLIQMILAEIESERDIPTV 808
K+ K +S L + + AK E E T N +++ + ++ S +D
Sbjct: 1479 REKETKALSLARAL---EEALEAKEE------LERT----NKMLKAEMEDLVSSKD---- 1521
Query: 809 STVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWL 868
V K+ E EK ++ L+ E+M K QL E E + E+ K L
Sbjct: 1522 -DVGKNVHELEKSKRA--LETQMEEM-----KTQL--------EELEDELQATEDAKLRL 1565
Query: 869 QMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEG 928
++ + Q ++ Q + EE+++ +Q + E + + +++ L ++ ++LE
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 929 TQKMKTQG-----------LLLEKENGQMRQIQKEAKHLGPHRRR--EKGKEKQKPERGL 975
+ ++ Q L K QM+ Q+E + R KE +K + L
Sbjct: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
Query: 976 EDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGK 1027
E Q++ + + +LEK + + S ++ L+D +R E +
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
Score = 54.7 bits (130), Expect = 1e-06
Identities = 131/688 (19%), Positives = 259/688 (37%), Gaps = 73/688 (10%)
Query: 231 NTKVSEIQGMLQELIGTTMFSTLENNAIKYISSTIVNLSTALSMLNDELKCVNFQSSTVY 290
N KV ++Q ++ + G M + E AIK ++ + +LS+ L Q +
Sbjct: 1279 NDKVHKLQNEVESVTG--MLNEAEGKAIK-LAKDVASLSSQL------------QDTQEL 1323
Query: 291 AHETSEAEKELSLKIIRDLSNENEMLQQKLQDAEEKCEQLIRSKIVIEQLYAKLSTSSTL 350
E + + +S K+ R L E LQ +L + E + L R STL
Sbjct: 1324 LQEETRQKLNVSTKL-RQLEEERNSLQDQLDEEMEAKQNLERH-------------ISTL 1369
Query: 351 KVLPGPSPQSSRAIIKVGDTEDNMDNILDKELENIVDEVQRKETKDSGIKWDSTISYTAQ 410
+ S + + + + KE+EN+ + + K ++
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
Query: 411 AERTPDLTELRQQPVASEDISEDSTKDNVSLKKGDFYQEDETDEYQSWKRSHKKATYVYE 470
+ DL RQ E + K DE D ++ R E
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK-------E 1482
Query: 471 TSGPNLSDNKSGQKVSEAKPSQYYELQVLKKKRKEMKSFSEDKSKSPTEAKRKHLSLTET 530
T +L+ ++ ++ EAK ++LK + +++ S +D K+ E ++ +L ET
Sbjct: 1483 TKALSLA--RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL-ET 1539
Query: 531 KSQGGKSGTSMMMLEQFRKVKRESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLS 590
+ + K+ + E + + A + + E ++ D++ + + R L L
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 591 MIQFD--------DTAEPQKGKIKGKKHHI---SSGTITSKEEKTEEKEELTKQVKSHQL 639
+ + A K K++G + + I +EE ++ +L Q+K Q
Sbjct: 1600 EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR 1659
Query: 640 VKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAFDKKTVPKE 699
+R +++ +T KS +++L + QE + A + + K D +
Sbjct: 1660 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR-----KQADLEKEELA 1714
Query: 700 EELLK--------RAEAEKLGIIKAKMEEYFQKVAETVTKIL-RKYKDTKKEEQVGEKPI 750
EEL + E +L A++EE ++ + + R K T++ EQ+ +
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
Query: 751 KQKKVV----SFMPGLHFQKSPISAK---SESSTLLSYESTDPVINNLIQMILAEIESER 803
++ S L Q + +K E + ++ST + I + ++E E
Sbjct: 1775 TERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA 1834
Query: 804 DIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHYEKISENWEE 863
+T K K+K+K+ +E LQ E+ K+Q +K+ ++ E EE
Sbjct: 1835 REKQAAT--KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE 1892
Query: 864 KKAWLQMKEGKQEQQSQKQWQEEEMWKE 891
+ + Q + + E M +E
Sbjct: 1893 SQRINANRRKLQRELDEATESNEAMGRE 1920
Score = 45.8 bits (107), Expect = 5e-04
Identities = 59/260 (22%), Positives = 114/260 (43%), Gaps = 23/260 (8%)
Query: 795 ILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQQLLGERNLLKEHY 854
+LA +E ERD+ + + + Q+Q++ M + Q RN Y
Sbjct: 774 VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQ-----RNCAA--Y 826
Query: 855 EKISENWEEKKAWLQMKE----GKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQR 910
K+ NW+ + + ++K +QE++ Q + E + KE Q++A + E E+K Q
Sbjct: 827 LKL-RNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885
Query: 911 GQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAK---HLGPHRRREKGKE 967
EE+ L + LQ E + + + L + ++ +I E + R ++ E
Sbjct: 886 -TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE 944
Query: 968 KQKPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQR--SYE 1025
++K + + DLE Q++ ++ + K +LEK+ + + V+ D S E
Sbjct: 945 RKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 1026 GKEFQRNLKTL-ENLPDEKE 1044
K + + L NL +E+E
Sbjct: 1001 RKLLEERISDLTTNLAEEEE 1020
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,826,190
Number of Sequences: 37866
Number of extensions: 5052902
Number of successful extensions: 55410
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 426
Number of HSP's successfully gapped in prelim test: 1896
Number of HSP's that attempted gapping in prelim test: 23547
Number of HSP's gapped (non-prelim): 15807
length of query: 2351
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2232
effective length of database: 13,741,464
effective search space: 30670947648
effective search space used: 30670947648
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.