Guide to the Human Genome
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Search of human proteins with 223972688

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223972688 adenosine deaminase domain containing 2 isoform 1
[Homo sapiens]
         (665 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223972688 adenosine deaminase domain containing 2 isoform 1 [...  1363   0.0  
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [...   901   0.0  
gi|226530771 adenosine deaminase domain containing 1 (testis-spe...   187   4e-47
gi|21245124 adenosine deaminase domain containing 1 (testis-spec...   187   4e-47
gi|226529650 adenosine deaminase domain containing 1 (testis-spe...   167   3e-41
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s...   137   3e-32
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]       130   4e-30
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo...   126   6e-29
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa...   108   1e-23
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa...   108   1e-23
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa...   105   2e-22
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa...   105   2e-22
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s...    84   5e-16
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s...    74   6e-13
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]         43   8e-04
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             42   0.002
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    39   0.020
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]            38   0.026
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    37   0.059
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    37   0.059
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              37   0.076
gi|45433499 zinc finger, DHHC-type containing 18 [Homo sapiens]        36   0.13 
gi|122937321 UNC homeobox [Homo sapiens]                               35   0.17 
gi|112421108 capicua homolog [Homo sapiens]                            35   0.17 
gi|13375642 kringle-containing transmembrane protein 2 isoform b...    35   0.17 
gi|7662010 zinc finger protein 516 [Homo sapiens]                      35   0.22 
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          34   0.50 
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    34   0.50 
gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]    34   0.50 
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...    34   0.50 

>gi|223972688 adenosine deaminase domain containing 2 isoform 1
           [Homo sapiens]
          Length = 665

 Score = 1363 bits (3528), Expect = 0.0
 Identities = 665/665 (100%), Positives = 665/665 (100%)

Query: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60
           MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ
Sbjct: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60

Query: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120
           VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL
Sbjct: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120

Query: 121 TEYAASLGIFLLFREDQPPGKVFKYRAPGGEELKAMCLWQVEVLRAFLLRTGWRGLWRGD 180
           TEYAASLGIFLLFREDQPPGKVFKYRAPGGEELKAMCLWQVEVLRAFLLRTGWRGLWRGD
Sbjct: 121 TEYAASLGIFLLFREDQPPGKVFKYRAPGGEELKAMCLWQVEVLRAFLLRTGWRGLWRGD 180

Query: 181 LDLGPDSSWANRLPFLLICEMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAK 240
           LDLGPDSSWANRLPFLLICEMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAK
Sbjct: 181 LDLGPDSSWANRLPFLLICEMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAK 240

Query: 241 QQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERS 300
           QQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERS
Sbjct: 241 QQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERS 300

Query: 301 PYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQ 360
           PYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQ
Sbjct: 301 PYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQ 360

Query: 361 QLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLY 420
           QLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLY
Sbjct: 361 QLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLY 420

Query: 421 ISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASD 480
           ISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASD
Sbjct: 421 ISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASD 480

Query: 481 KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540
           KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPP
Sbjct: 481 KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540

Query: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRL 600
           YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRL
Sbjct: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRL 600

Query: 601 CKASFLRAFHQAARAVGKPYLLALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLV 660
           CKASFLRAFHQAARAVGKPYLLALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLV
Sbjct: 601 CKASFLRAFHQAARAVGKPYLLALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLV 660

Query: 661 GKFRN 665
           GKFRN
Sbjct: 661 GKFRN 665


>gi|223972690 adenosine deaminase domain containing 2 isoform 2
           [Homo sapiens]
          Length = 583

 Score =  901 bits (2329), Expect = 0.0
 Identities = 444/454 (97%), Positives = 444/454 (97%), Gaps = 10/454 (2%)

Query: 212 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP 271
           GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP
Sbjct: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP 199

Query: 272 LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRA 331
           LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILER          EIPRA
Sbjct: 200 LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILER----------EIPRA 249

Query: 332 RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP 391
           RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP
Sbjct: 250 RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP 309

Query: 392 KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ 451
           KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ
Sbjct: 310 KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ 369

Query: 452 AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD 511
           AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD
Sbjct: 370 AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD 429

Query: 512 SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW 571
           SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW
Sbjct: 430 SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW 489

Query: 572 SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK 631
           SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK
Sbjct: 490 SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK 549

Query: 632 AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN 665
           AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN
Sbjct: 550 AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN 583



 Score =  290 bits (742), Expect = 3e-78
 Identities = 141/145 (97%), Positives = 142/145 (97%)

Query: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60
           MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ
Sbjct: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60

Query: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120
           VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL
Sbjct: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120

Query: 121 TEYAASLGIFLLFREDQPPGKVFKY 145
           TEYAASLGIFLLFREDQPPG  F +
Sbjct: 121 TEYAASLGIFLLFREDQPPGPCFPF 145


>gi|226530771 adenosine deaminase domain containing 1
           (testis-specific) isoform 3 [Homo sapiens]
          Length = 558

 Score =  187 bits (474), Expect = 4e-47
 Identities = 153/490 (31%), Positives = 240/490 (48%), Gaps = 54/490 (11%)

Query: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259
           +++  +     +GP F F   A +DG+    G   +K E++  AA  AL  +  QL+ PE
Sbjct: 95  DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 151

Query: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304
               +TS  PP       L+ L+  + + +E R       + +V   F+ L+  RS Y  
Sbjct: 152 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 211

Query: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364
              ++A  I+ER                      +++VA+GTG    +  ++  G+ LHD
Sbjct: 212 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 252

Query: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424
            H +V ARR+LLR+ +RQLLL     P   E+S+   +P      TLK  + + LY++  
Sbjct: 253 THAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQL 311

Query: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481
           PKG+A+    + L P S      +  + L   V G++    Y  P      +  +S+SDK
Sbjct: 312 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 370

Query: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540
           L RW VLG+ GALL+H + P+Y +S+++ D +C D   L  AI  R  +D  L   LP  
Sbjct: 371 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 428

Query: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596
           Y+    H+   P   P +   +  + LSLNW+ GD  +E+VD  +G++  +    + +  
Sbjct: 429 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 487

Query: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654
            SRLCKA+ L  F+  A+   K  LL   TY AAK  +  YQEA+ +L   L Q G G+W
Sbjct: 488 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 546

Query: 655 PSK-PLVGKF 663
             K P + +F
Sbjct: 547 IVKSPCIEQF 556


>gi|21245124 adenosine deaminase domain containing 1
           (testis-specific) isoform 1 [Homo sapiens]
          Length = 576

 Score =  187 bits (474), Expect = 4e-47
 Identities = 153/490 (31%), Positives = 240/490 (48%), Gaps = 54/490 (11%)

Query: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259
           +++  +     +GP F F   A +DG+    G   +K E++  AA  AL  +  QL+ PE
Sbjct: 113 DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 169

Query: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304
               +TS  PP       L+ L+  + + +E R       + +V   F+ L+  RS Y  
Sbjct: 170 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 229

Query: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364
              ++A  I+ER                      +++VA+GTG    +  ++  G+ LHD
Sbjct: 230 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 270

Query: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424
            H +V ARR+LLR+ +RQLLL     P   E+S+   +P      TLK  + + LY++  
Sbjct: 271 THAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQL 329

Query: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481
           PKG+A+    + L P S      +  + L   V G++    Y  P      +  +S+SDK
Sbjct: 330 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 388

Query: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540
           L RW VLG+ GALL+H + P+Y +S+++ D +C D   L  AI  R  +D  L   LP  
Sbjct: 389 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 446

Query: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596
           Y+    H+   P   P +   +  + LSLNW+ GD  +E+VD  +G++  +    + +  
Sbjct: 447 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 505

Query: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654
            SRLCKA+ L  F+  A+   K  LL   TY AAK  +  YQEA+ +L   L Q G G+W
Sbjct: 506 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 564

Query: 655 PSK-PLVGKF 663
             K P + +F
Sbjct: 565 IVKSPCIEQF 574


>gi|226529650 adenosine deaminase domain containing 1
           (testis-specific) isoform 2 [Homo sapiens]
          Length = 565

 Score =  167 bits (423), Expect = 3e-41
 Identities = 147/490 (30%), Positives = 232/490 (47%), Gaps = 65/490 (13%)

Query: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259
           +++  +     +GP F F   A +DG+    G   +K E++  AA  AL  +  QL+ PE
Sbjct: 113 DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 169

Query: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304
               +TS  PP       L+ L+  + + +E R       + +V   F+ L+  RS Y  
Sbjct: 170 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 229

Query: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364
              ++A  I+ER                      +++VA+GTG    +  ++  G+ LHD
Sbjct: 230 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 270

Query: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424
            H +V ARR+LL              P   E+S+   +P      TLK  + + LY++  
Sbjct: 271 THAVVTARRSLL-----------SKNPAMMEKSIFCTEPTSNL-LTLKQNINICLYMNQL 318

Query: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481
           PKG+A+    + L P S      +  + L   V G++    Y  P      +  +S+SDK
Sbjct: 319 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 377

Query: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540
           L RW VLG+ GALL+H + P+Y +S+++ D +C D   L  AI  R  +D  L   LP  
Sbjct: 378 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 435

Query: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596
           Y+    H+   P   P +   +  + LSLNW+ GD  +E+VD  +G++  +    + +  
Sbjct: 436 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 494

Query: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654
            SRLCKA+ L  F+  A+   K  LL   TY AAK  +  YQEA+ +L   L Q G G+W
Sbjct: 495 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 553

Query: 655 PSK-PLVGKF 663
             K P + +F
Sbjct: 554 IVKSPCIEQF 563


>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
           sapiens]
          Length = 701

 Score =  137 bits (345), Expect = 3e-32
 Identities = 140/465 (30%), Positives = 211/465 (45%), Gaps = 59/465 (12%)

Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276
           F +S  +DG     G+  +K  AK +AA SAL  I     N    QT SR P+    ++ 
Sbjct: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317

Query: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334
            L        + LV   F  L D  S   A +  +AGV++  G        T++  A   
Sbjct: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366

Query: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393
                K++++ TG+ C  G ++   G  L+DCH  +I+RR+LLRFL+ QL L        
Sbjct: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421

Query: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEGGLPHSPPMRLQ 451
           K       + G    F LK  V  HLYIS +P G AR I+ P  P  E      P  + +
Sbjct: 422 KRSIFQKSERGG---FRLKENVQFHLYISTSPCGDAR-IFSPHEPILEEPADRHPNRKAR 477

Query: 452 AHVLGQLKPVCYVAPSLCDTHVGC------------LSASDKLARWAVLGLGGALLAHLV 499
             +  +++      P   +  +              +S SDK+ARW V+G+ G+LL+  V
Sbjct: 478 GQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFV 537

Query: 500 SPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEP 559
            P+Y +S+IL    H    LSRA++ R  + ++    LPP Y      L +G   A +  
Sbjct: 538 EPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--EDLPPLYTLNK-PLLSGISNAEAR- 590

Query: 560 TPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCK----ASFLRAFHQAARA 615
            P      S+NW++GD  IEV++  TG+ +    LG  SRLCK      ++R   +    
Sbjct: 591 QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LGRASRLCKHALYCRWMRVHGKVPSH 646

Query: 616 VGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAWPSKP 658
           + +  +     Y  +K  A  YQ A+ +L     + GLGAW  KP
Sbjct: 647 LLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKP 691


>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
          Length = 739

 Score =  130 bits (327), Expect = 4e-30
 Identities = 131/463 (28%), Positives = 205/463 (44%), Gaps = 60/463 (12%)

Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276
           F ++  +DG     G+  SK  A+ QAA +AL  +        +P  + R P+     ++
Sbjct: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADS 364

Query: 277 ILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVK 336
           I       + LV+  F  +  + +P  A    +AG+++ +G                   
Sbjct: 365 I-------SQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQA------------- 404

Query: 337 EIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKE 395
              ++VAL +G+ C +G  L   G  ++DCH  V+ARRA L FL+ QL L      +  E
Sbjct: 405 ---QVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSE 461

Query: 396 QSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPM--RLQAH 453
           +S+       G  + L+  +  HLY+S +P G AR ++ P      L  S  +  + + H
Sbjct: 462 RSIFVRLKEGG--YRLRENILFHLYVSTSPCGDAR-LHSPYEITTDLHSSKHLVRKFRGH 518

Query: 454 VLGQLKP----VCYVAPSLCDTHVGCL--------SASDKLARWAVLGLGGALLAHLVSP 501
           +  +++     V    PS   T  G L        S +DK+ARW VLGL GALL+H V P
Sbjct: 519 LRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578

Query: 502 LYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTP 561
           +Y  S+++  S H    L+R +  R     + G    P   R    L +G   A +   P
Sbjct: 579 VYLQSIVVG-SLHHTGHLARVMSHR-----MEGVGQLPASYRHNRPLLSGVSDAEAR-QP 631

Query: 562 DTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCK----ASFLRAFHQAARAVG 617
                 S+NW +G   +E+++  TGR     + G PSRLCK    A + R + + +    
Sbjct: 632 GKSPPFSMNWVVGSADLEIINATTGR----RSCGGPSRLCKHVLSARWARLYGRLSTRTP 687

Query: 618 KPYLLALKTYEAAKAG--PYQEARRQLSLLLDQQGLGAWPSKP 658
            P       Y  AK G   YQ  ++QL     + GLG W  KP
Sbjct: 688 SPGDTP-SMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKP 729


>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
           sapiens]
          Length = 674

 Score =  126 bits (317), Expect = 6e-29
 Identities = 137/446 (30%), Positives = 202/446 (45%), Gaps = 67/446 (15%)

Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276
           F +S  +DG     G+  +K  AK +AA SAL  I     N    QT SR P+    ++ 
Sbjct: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317

Query: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334
            L        + LV   F  L D  S   A +  +AGV++  G        T++  A   
Sbjct: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366

Query: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393
                K++++ TG+ C  G ++   G  L+DCH  +I+RR+LLRFL+ QL L        
Sbjct: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421

Query: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEGGLPHSPPMRLQ 451
           K       + G    F LK  V  HLYIS +P G AR I+ P  P  E      P  + +
Sbjct: 422 KRSIFQKSERGG---FRLKENVQFHLYISTSPCGDAR-IFSPHEPILEEPADRHPNRKAR 477

Query: 452 AHVLGQLKPVCYVAPSLCDTHVGC------------LSASDKLARWAVLGLGGALLAHLV 499
             +  +++      P   +  +              +S SDK+ARW V+G+ G+LL+  V
Sbjct: 478 GQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFV 537

Query: 500 SPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEP 559
            P+Y +S+IL    H    LSRA++ R  + ++    LPP Y      L +G   A +  
Sbjct: 538 EPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--EDLPPLYTLNK-PLLSGISNAEAR- 590

Query: 560 TPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCK-ASFLR--------AFH 610
            P      S+NW++GD  IEV++  TG+ +    LG  SRLCK A + R          H
Sbjct: 591 QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LGRASRLCKHALYCRWMRVHGKVPSH 646

Query: 611 QAARAVGKPYL-----LALKTYEAAK 631
                + KP +     LA K Y+AAK
Sbjct: 647 LLRSKITKPNVYHESKLAAKEYQAAK 672


>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
            sapiens]
          Length = 1181

 Score =  108 bits (271), Expect = 1e-23
 Identities = 128/476 (26%), Positives = 198/476 (41%), Gaps = 58/476 (12%)

Query: 208  VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265
            V++ GP     F   A++ G   PA  A+SK + KQ+AA +AL  +  + E  E    + 
Sbjct: 728  VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 787

Query: 266  RPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSC 325
             P       + I     RC       F+ L +   P    +  +A +I+++         
Sbjct: 788  LPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKILAAIIMKKD-------- 832

Query: 326  TEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLL 384
                      +++  +V+LGTG+ C  G  L   G+ ++DCH  +I+RR  +RFL+ +L+
Sbjct: 833  ---------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELM 883

Query: 385  LATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARDIYLPPT 437
               +   +  + S+  P  G G    +K  V  HLYIS  P G       +  D  +  T
Sbjct: 884  ---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 939

Query: 438  SEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASDKLARWA 486
                 P   +P   +L+  V      +   +  +  T  G         +S SDK+ RW 
Sbjct: 940  ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 999

Query: 487  VLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPPPYVRTA 545
            VLGL GALL H + P+Y  S+ L         L+RAI  R   D S     L  P++   
Sbjct: 1000 VLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRHPFI--V 1056

Query: 546  LHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPPSRLCKA 603
             H   G   +  S+      +  S+NW L D   +E++D   G V  +      SR+ K 
Sbjct: 1057 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNELSRVSKK 1114

Query: 604  SFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPSKP 658
            +    F +      +  LL L   EA KA   Y+ A+      L   G G W SKP
Sbjct: 1115 NIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKP 1170


>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
            sapiens]
          Length = 1200

 Score =  108 bits (271), Expect = 1e-23
 Identities = 128/476 (26%), Positives = 198/476 (41%), Gaps = 58/476 (12%)

Query: 208  VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265
            V++ GP     F   A++ G   PA  A+SK + KQ+AA +AL  +  + E  E    + 
Sbjct: 747  VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 806

Query: 266  RPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSC 325
             P       + I     RC       F+ L +   P    +  +A +I+++         
Sbjct: 807  LPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKILAAIIMKKD-------- 851

Query: 326  TEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLL 384
                      +++  +V+LGTG+ C  G  L   G+ ++DCH  +I+RR  +RFL+ +L+
Sbjct: 852  ---------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELM 902

Query: 385  LATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARDIYLPPT 437
               +   +  + S+  P  G G    +K  V  HLYIS  P G       +  D  +  T
Sbjct: 903  ---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 958

Query: 438  SEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASDKLARWA 486
                 P   +P   +L+  V      +   +  +  T  G         +S SDK+ RW 
Sbjct: 959  ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 1018

Query: 487  VLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPPPYVRTA 545
            VLGL GALL H + P+Y  S+ L         L+RAI  R   D S     L  P++   
Sbjct: 1019 VLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRHPFI--V 1075

Query: 546  LHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPPSRLCKA 603
             H   G   +  S+      +  S+NW L D   +E++D   G V  +      SR+ K 
Sbjct: 1076 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNELSRVSKK 1133

Query: 604  SFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPSKP 658
            +    F +      +  LL L   EA KA   Y+ A+      L   G G W SKP
Sbjct: 1134 NIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKP 1189


>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
           sapiens]
          Length = 931

 Score =  105 bits (261), Expect = 2e-22
 Identities = 129/495 (26%), Positives = 202/495 (40%), Gaps = 70/495 (14%)

Query: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265
           V++ GP     F   A++ G   PA  A+SK + KQ+AA +AL  +  + E  E    + 
Sbjct: 452 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 511

Query: 266 RPPLAPLSVENIL-------------------THEQRCAALVSAGFDLLLDERSPYWACK 306
             P+   S+   +                   T   + A L    F+ L +   P    +
Sbjct: 512 VTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 571

Query: 307 GTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDC 365
             +A +I+++                   +++  +V+LGTG+ C  G  L   G+ ++DC
Sbjct: 572 KILAAIIMKKD-----------------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDC 614

Query: 366 HGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTP 425
           H  +I+RR  +RFL+ +L+   +   +  + S+  P  G G    +K  V  HLYIS  P
Sbjct: 615 HAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAP 670

Query: 426 KG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG- 474
            G       +  D  +  T     P   +P   +L+  V      +   +  +  T  G 
Sbjct: 671 CGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGI 730

Query: 475 -------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRP 527
                   +S SDK+ RW VLGL GALL H + P+Y  S+ L         L+RAI  R 
Sbjct: 731 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRV 789

Query: 528 CLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVA 584
             D S     L  P++    H   G   +  S+      +  S+NW L D   +E++D  
Sbjct: 790 TRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGT 847

Query: 585 TGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLS 643
            G V  +      SR+ K +    F +      +  LL L   EA KA   Y+ A+    
Sbjct: 848 RGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 905

Query: 644 LLLDQQGLGAWPSKP 658
             L   G G W SKP
Sbjct: 906 KGLKDMGYGNWISKP 920


>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
            sapiens]
          Length = 1226

 Score =  105 bits (261), Expect = 2e-22
 Identities = 129/495 (26%), Positives = 202/495 (40%), Gaps = 70/495 (14%)

Query: 208  VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265
            V++ GP     F   A++ G   PA  A+SK + KQ+AA +AL  +  + E  E    + 
Sbjct: 747  VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 806

Query: 266  RPPLAPLSVENIL-------------------THEQRCAALVSAGFDLLLDERSPYWACK 306
              P+   S+   +                   T   + A L    F+ L +   P    +
Sbjct: 807  VTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 866

Query: 307  GTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDC 365
              +A +I+++                   +++  +V+LGTG+ C  G  L   G+ ++DC
Sbjct: 867  KILAAIIMKKD-----------------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDC 909

Query: 366  HGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTP 425
            H  +I+RR  +RFL+ +L+   +   +  + S+  P  G G    +K  V  HLYIS  P
Sbjct: 910  HAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAP 965

Query: 426  KG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG- 474
             G       +  D  +  T     P   +P   +L+  V      +   +  +  T  G 
Sbjct: 966  CGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGI 1025

Query: 475  -------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRP 527
                    +S SDK+ RW VLGL GALL H + P+Y  S+ L         L+RAI  R 
Sbjct: 1026 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRV 1084

Query: 528  CLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVA 584
              D S     L  P++    H   G   +  S+      +  S+NW L D   +E++D  
Sbjct: 1085 TRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGT 1142

Query: 585  TGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLS 643
             G V  +      SR+ K +    F +      +  LL L   EA KA   Y+ A+    
Sbjct: 1143 RGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200

Query: 644  LLLDQQGLGAWPSKP 658
              L   G G W SKP
Sbjct: 1201 KGLKDMGYGNWISKP 1215


>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
           sapiens]
          Length = 741

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 17/189 (8%)

Query: 476 LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGP 535
           +S SDK+ARW V+G+ G+LL+  V P+Y +S+IL    H    LSRA++ R  + ++   
Sbjct: 554 MSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--E 608

Query: 536 CLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALG 595
            LPP Y      L +G   A +   P      S+NW++GD  IEV++  TG+ +    LG
Sbjct: 609 DLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LG 662

Query: 596 PPSRLCK----ASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQ 649
             SRLCK      ++R   +    + +  +     Y  +K  A  YQ A+ +L     + 
Sbjct: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKA 722

Query: 650 GLGAWPSKP 658
           GLGAW  KP
Sbjct: 723 GLGAWVEKP 731



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 75/229 (32%), Positives = 105/229 (45%), Gaps = 30/229 (13%)

Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276
           F +S  +DG     G+  +K  AK +AA SAL  I     N    QT SR P+    ++ 
Sbjct: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317

Query: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334
            L        + LV   F  L D  S   A +  +AGV++  G        T++  A   
Sbjct: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366

Query: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393
                K++++ TG+ C  G ++   G  L+DCH  +I+RR+LLRFL+ QL L        
Sbjct: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421

Query: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEG 440
           K       + G    F LK  V  HLYIS +P G AR I+ P  P  EG
Sbjct: 422 KRSIFQKSERG---GFRLKENVQFHLYISTSPCGDAR-IFSPHEPILEG 466


>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
           sapiens]
          Length = 714

 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 75/229 (32%), Positives = 105/229 (45%), Gaps = 30/229 (13%)

Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276
           F +S  +DG     G+  +K  AK +AA SAL  I     N    QT SR P+    ++ 
Sbjct: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317

Query: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334
            L        + LV   F  L D  S   A +  +AGV++  G        T++  A   
Sbjct: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366

Query: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393
                K++++ TG+ C  G ++   G  L+DCH  +I+RR+LLRFL+ QL L        
Sbjct: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421

Query: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEG 440
           K       + G    F LK  V  HLYIS +P G AR I+ P  P  EG
Sbjct: 422 KRSIFQKSERG---GFRLKENVQFHLYISTSPCGDAR-IFSPHEPILEG 466



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 61/170 (35%), Positives = 88/170 (51%), Gaps = 25/170 (14%)

Query: 476 LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGP 535
           +S SDK+ARW V+G+ G+LL+  V P+Y +S+IL    H    LSRA++ R  + ++   
Sbjct: 554 MSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--E 608

Query: 536 CLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALG 595
            LPP Y      L +G   A +   P      S+NW++GD  IEV++  TG+ +    LG
Sbjct: 609 DLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LG 662

Query: 596 PPSRLCK-ASFLR--------AFHQAARAVGKPYL-----LALKTYEAAK 631
             SRLCK A + R          H     + KP +     LA K Y+AAK
Sbjct: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712


>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
          Length = 502

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 31/91 (34%), Positives = 47/91 (51%), Gaps = 6/91 (6%)

Query: 340 KLVALGTGSSCCA-GWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSV 398
           ++V++GTG+ C     +  +G  L+D H  VIARR+  R+L  QL LA       KE S+
Sbjct: 60  EIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQLAA----TLKEDSI 115

Query: 399 LAPQPGPGPPFTLKPRVFLHLYISNTPKGAA 429
             P    G  + L+  +    + S+TP G A
Sbjct: 116 FVPGTQKG-VWKLRRDLIFVFFSSHTPCGDA 145



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 20/49 (40%), Positives = 32/49 (65%), Gaps = 1/49 (2%)

Query: 476 LSASDKLARWAVLGLGGALLAHLV-SPLYSTSLILADSCHDPPTLSRAI 523
           +S SDK+ARW VLG  GALL HL+  P+Y +++++    +    + RA+
Sbjct: 297 MSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRAL 345


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 19/121 (15%)

Query: 2   ASASQGADDDGSRR----------KPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPAT 51
           +SA  GA+ DG +           KPR+   LQ    P   RP PA  +++    PAP T
Sbjct: 259 SSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPT 318

Query: 52  YRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDP 111
            R      Q +++        AG   L   R  E     + K    P P  G   P KDP
Sbjct: 319 PRPRSSLQQENLVEQ------AGSSSLVNGRLHE---LPVPKPRGTPKPSEGTPAPRKDP 369

Query: 112 P 112
           P
Sbjct: 370 P 370


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 10/93 (10%)

Query: 29   PRPWRPLPAQAQSAWGPAPAPATY--RAEGGWPQVSVLRDSGPGAGAGVGELGAARAW-- 84
            P P +PLP+ A  A  PAP PA +  R      +    + +GP  GAG+ + G  R +  
Sbjct: 909  PPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLAD-GFHRYYGP 967

Query: 85   ---ENLGEQMGKAPRVPVPPAG--LSLPLKDPP 112
               + LG  +G+A   P   AG  LS P   PP
Sbjct: 968  IEPQGLGLGLGEARAAPRGAAGRPLSPPAAQPP 1000


>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 33/101 (32%), Positives = 40/101 (39%), Gaps = 7/101 (6%)

Query: 12  GSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPA--TYRAEGGWPQVSVLRDSGP 69
           GS+  P     L    +   W P PA+A  A G    PA    RA G     +  R   P
Sbjct: 64  GSQEHPGAGGPLCFPARSAAWGP-PARASRAAGRRAGPAGPPCRAPGRGRAAATRRSPAP 122

Query: 70  GAG----AGVGELGAARAWENLGEQMGKAPRVPVPPAGLSL 106
           G      AGV   G A A  + G +   A R+P P  G SL
Sbjct: 123 GTARGSPAGVERAGGATAASSAGTRSVPARRLPPPCGGTSL 163


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 37.0 bits (84), Expect = 0.059
 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 29  PRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLG 88
           PRP  P P        PAP+P T+ ++   P  SV R  GPG GA  G  G  R  E   
Sbjct: 125 PRPPPPRPGMHSPPPRPAPSPGTWESQ---PARSV-RLGGPGGGA--GGAGGGRVLECPS 178

Query: 89  EQMGKAPRVPVPPAGL 104
            ++      P PPA L
Sbjct: 179 IRITSISPTPEPPAAL 194


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 37.0 bits (84), Expect = 0.059
 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 29  PRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLG 88
           PRP  P P        PAP+P T+ ++   P  SV R  GPG GA  G  G  R  E   
Sbjct: 62  PRPPPPRPGMHSPPPRPAPSPGTWESQ---PARSV-RLGGPGGGA--GGAGGGRVLECPS 115

Query: 89  EQMGKAPRVPVPPAGL 104
            ++      P PPA L
Sbjct: 116 IRITSISPTPEPPAAL 131


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 36.6 bits (83), Expect = 0.076
 Identities = 39/123 (31%), Positives = 48/123 (39%), Gaps = 24/123 (19%)

Query: 20  AASLQI----SPQPRPWRPLPAQAQSAWG-----PAPAPATYRAEGGWPQVSV------- 63
           A +LQI    SP P P  P PA A SA G     P   P      GG P+  V       
Sbjct: 822 ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881

Query: 64  -------LRDSGPGAGAGVGELGAARAWENLGEQM-GKAPRVPVPPAGLSLPLKDPPASQ 115
                  LR  G   GA    LG +   + L   + G+A  VP P +GL   ++    S 
Sbjct: 882 SLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSL 941

Query: 116 AVS 118
           A S
Sbjct: 942 AAS 944


>gi|45433499 zinc finger, DHHC-type containing 18 [Homo sapiens]
          Length = 388

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 11/68 (16%)

Query: 20 AASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELG 79
          AA L  SP  R  RP PA + +  GP PAP    A   W        SG G+G+G G LG
Sbjct: 13 AAPLPASPGAR--RPGPAASPTP-GPGPAPPAAPAPPRWSS------SGSGSGSGSGSLG 63

Query: 80 --AARAWE 85
              R WE
Sbjct: 64 RRPRRKWE 71


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 10/108 (9%)

Query: 27  PQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQV------SVLRDSGPGAGAGVGELGA 80
           PQPRP RP    A S    A   A  R   G P+       S+L DS P   A      A
Sbjct: 295 PQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAA 354

Query: 81  ARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLG 128
           A A  +    +  APR  +      L     P +Q +  L   AA  G
Sbjct: 355 AAAGLDFAPGLPCAPRTLIGKGHFLL----YPITQPLGFLVPQAALKG 398


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 30/88 (34%), Positives = 37/88 (42%), Gaps = 3/88 (3%)

Query: 35  LPAQAQSAWGPAPAPATYRA--EGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMG 92
           LP Q Q A  PAPAP T  A   G  P  S+     PG     G++ AA A       + 
Sbjct: 832 LPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTN-GKVLAATAPTPGIPILQ 890

Query: 93  KAPRVPVPPAGLSLPLKDPPASQAVSLL 120
             P  P P A    P++ PP   +  LL
Sbjct: 891 SVPSAPPPKAQSVSPVQAPPPGGSAQLL 918


>gi|13375642 kringle-containing transmembrane protein 2 isoform b
           precursor [Homo sapiens]
          Length = 420

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 13/111 (11%)

Query: 236 KTEAKQQAALSALCY--IRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFD 293
           +++A+  A   AL Y  ++   E+PE+P+ S++ P APL   N+    +  A   + G  
Sbjct: 309 RSDARGHAQGFALTYRGLQDAAEDPEAPEGSAQTPAAPLDGANVSCSPRPGAPPAAIGGA 368

Query: 294 LL-LDERSP-YWACKGT-----VAGVILERGWAVSAPSCTE----IPRARG 333
           +  L E+ P  W   G      + G     GW   AP  T     +PRA G
Sbjct: 369 VCWLREKGPRRWGLPGAPGEAGLCGTNSPEGWPCPAPPGTPRLRVLPRATG 419


>gi|7662010 zinc finger protein 516 [Homo sapiens]
          Length = 1163

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 35/131 (26%), Positives = 49/131 (37%), Gaps = 18/131 (13%)

Query: 7    GADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPA--PAPATYRAEGGWPQVS-- 62
            GA   G   KPR  AS          +P+PA     +  +  P P      G  P  +  
Sbjct: 898  GAATQGPLAKPRQEASS---------KPVPAPGGGGFSRSATPTPTVIARAGAQPSANSK 948

Query: 63   -VLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLS----LPLKDPPASQAV 117
             V +   P AGAG        A ++L  +    P+ P P  G      LP ++PP+  A 
Sbjct: 949  PVEKFGVPPAGAGFAPTNKHSAPDSLKAKFSAQPQGPPPAKGEGGAPPLPPREPPSKAAQ 1008

Query: 118  SLLTEYAASLG 128
             L T    + G
Sbjct: 1009 ELRTLATCAAG 1019


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 14/93 (15%)

Query: 48  APATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLP 107
           A AT  A GG    +    +  G GAG G  G     +   + +  +   P PPAG   P
Sbjct: 236 AAATAAAAGGGGSTA---STSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPP 292

Query: 108 LKDPPASQAVSLLTEYAASLGIFLLFREDQPPG 140
           L  PP     + +T  +A           QPPG
Sbjct: 293 LTLPPTPSPATAVTAASA-----------QPPG 314


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 18/43 (41%), Positives = 21/43 (48%)

Query: 34  PLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVG 76
           P+PA A  A GP PAPA      G   ++     GPG G G G
Sbjct: 139 PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 30/94 (31%), Positives = 36/94 (38%), Gaps = 10/94 (10%)

Query: 27  PQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWEN 86
           P   P  P PA AQ+      APA   A GG     V    GPGA A     G       
Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG--PAGVSGQPGPGAAAAAPAPG------- 341

Query: 87  LGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120
           +  +  K      PPA  +L     PAS A S++
Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASG-PASTAASMV 374


>gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]
          Length = 773

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 17/36 (47%), Positives = 22/36 (61%)

Query: 213 PCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSAL 248
           P  PF  S  +DGV   +GTA+SK  AK +AA + L
Sbjct: 538 PSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATL 573


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 38/157 (24%), Positives = 61/157 (38%), Gaps = 15/157 (9%)

Query: 27  PQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWEN 86
           P+P P  P P   + +   A  P++  A     + + L+   P +   V  LG A+  E+
Sbjct: 36  PEPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWV--LGGAKPAED 93

Query: 87  L---------GEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQ 137
                     GE  G+    P+P      P  +PP  Q  S  +E  A  G         
Sbjct: 94  TSLGPGVPGTGEPAGEIWYNPIPEEDPRPPAPEPPGPQPGSAESEGLAPQGA----APAS 149

Query: 138 PPGKVFKYRAPGGEELKAMCLWQVEVLRAFLLRTGWR 174
           PP K  + ++PG     ++ + ++  LR  L   G R
Sbjct: 150 PPTKASRTKSPGPARRLSIKMKKLPELRRRLSLRGPR 186


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,037,967
Number of Sequences: 37866
Number of extensions: 1846920
Number of successful extensions: 7316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 7030
Number of HSP's gapped (non-prelim): 368
length of query: 665
length of database: 18,247,518
effective HSP length: 109
effective length of query: 556
effective length of database: 14,120,124
effective search space: 7850788944
effective search space used: 7850788944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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