BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|223972688 adenosine deaminase domain containing 2 isoform 1 [Homo sapiens] (665 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 1363 0.0 gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 901 0.0 gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 187 4e-47 gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 187 4e-47 gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 167 3e-41 gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 137 3e-32 gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 130 4e-30 gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 126 6e-29 gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 108 1e-23 gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 108 1e-23 gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 105 2e-22 gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 105 2e-22 gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 84 5e-16 gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 74 6e-13 gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 43 8e-04 gi|31324577 molecule interacting with Rab13 [Homo sapiens] 42 0.002 gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 39 0.020 gi|239753839 PREDICTED: hypothetical protein [Homo sapiens] 38 0.026 gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c... 37 0.059 gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca... 37 0.059 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 37 0.076 gi|45433499 zinc finger, DHHC-type containing 18 [Homo sapiens] 36 0.13 gi|122937321 UNC homeobox [Homo sapiens] 35 0.17 gi|112421108 capicua homolog [Homo sapiens] 35 0.17 gi|13375642 kringle-containing transmembrane protein 2 isoform b... 35 0.17 gi|7662010 zinc finger protein 516 [Homo sapiens] 35 0.22 gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 34 0.50 gi|110832843 TBP-associated factor 4 [Homo sapiens] 34 0.50 gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens] 34 0.50 gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 34 0.50 >gi|223972688 adenosine deaminase domain containing 2 isoform 1 [Homo sapiens] Length = 665 Score = 1363 bits (3528), Expect = 0.0 Identities = 665/665 (100%), Positives = 665/665 (100%) Query: 1 MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60 MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ Sbjct: 1 MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60 Query: 61 VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120 VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL Sbjct: 61 VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120 Query: 121 TEYAASLGIFLLFREDQPPGKVFKYRAPGGEELKAMCLWQVEVLRAFLLRTGWRGLWRGD 180 TEYAASLGIFLLFREDQPPGKVFKYRAPGGEELKAMCLWQVEVLRAFLLRTGWRGLWRGD Sbjct: 121 TEYAASLGIFLLFREDQPPGKVFKYRAPGGEELKAMCLWQVEVLRAFLLRTGWRGLWRGD 180 Query: 181 LDLGPDSSWANRLPFLLICEMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAK 240 LDLGPDSSWANRLPFLLICEMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAK Sbjct: 181 LDLGPDSSWANRLPFLLICEMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAK 240 Query: 241 QQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERS 300 QQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERS Sbjct: 241 QQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERS 300 Query: 301 PYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQ 360 PYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQ Sbjct: 301 PYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQ 360 Query: 361 QLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLY 420 QLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLY Sbjct: 361 QLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLY 420 Query: 421 ISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASD 480 ISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASD Sbjct: 421 ISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASD 480 Query: 481 KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540 KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPP Sbjct: 481 KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540 Query: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRL 600 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRL Sbjct: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRL 600 Query: 601 CKASFLRAFHQAARAVGKPYLLALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLV 660 CKASFLRAFHQAARAVGKPYLLALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLV Sbjct: 601 CKASFLRAFHQAARAVGKPYLLALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLV 660 Query: 661 GKFRN 665 GKFRN Sbjct: 661 GKFRN 665 >gi|223972690 adenosine deaminase domain containing 2 isoform 2 [Homo sapiens] Length = 583 Score = 901 bits (2329), Expect = 0.0 Identities = 444/454 (97%), Positives = 444/454 (97%), Gaps = 10/454 (2%) Query: 212 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP 271 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP Sbjct: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP 199 Query: 272 LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRA 331 LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILER EIPRA Sbjct: 200 LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILER----------EIPRA 249 Query: 332 RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP 391 RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP Sbjct: 250 RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP 309 Query: 392 KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ 451 KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ Sbjct: 310 KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ 369 Query: 452 AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD 511 AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD Sbjct: 370 AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD 429 Query: 512 SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW 571 SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW Sbjct: 430 SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW 489 Query: 572 SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK 631 SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK Sbjct: 490 SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK 549 Query: 632 AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN 665 AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN Sbjct: 550 AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN 583 Score = 290 bits (742), Expect = 3e-78 Identities = 141/145 (97%), Positives = 142/145 (97%) Query: 1 MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60 MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ Sbjct: 1 MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60 Query: 61 VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120 VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL Sbjct: 61 VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120 Query: 121 TEYAASLGIFLLFREDQPPGKVFKY 145 TEYAASLGIFLLFREDQPPG F + Sbjct: 121 TEYAASLGIFLLFREDQPPGPCFPF 145 >gi|226530771 adenosine deaminase domain containing 1 (testis-specific) isoform 3 [Homo sapiens] Length = 558 Score = 187 bits (474), Expect = 4e-47 Identities = 153/490 (31%), Positives = 240/490 (48%), Gaps = 54/490 (11%) Query: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259 +++ + +GP F F A +DG+ G +K E++ AA AL + QL+ PE Sbjct: 95 DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 151 Query: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304 +TS PP L+ L+ + + +E R + +V F+ L+ RS Y Sbjct: 152 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 211 Query: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364 ++A I+ER +++VA+GTG + ++ G+ LHD Sbjct: 212 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 252 Query: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424 H +V ARR+LLR+ +RQLLL P E+S+ +P TLK + + LY++ Sbjct: 253 THAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQL 311 Query: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481 PKG+A+ + L P S + + L V G++ Y P + +S+SDK Sbjct: 312 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 370 Query: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540 L RW VLG+ GALL+H + P+Y +S+++ D +C D L AI R +D L LP Sbjct: 371 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 428 Query: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596 Y+ H+ P P + + + LSLNW+ GD +E+VD +G++ + + + Sbjct: 429 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 487 Query: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654 SRLCKA+ L F+ A+ K LL TY AAK + YQEA+ +L L Q G G+W Sbjct: 488 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 546 Query: 655 PSK-PLVGKF 663 K P + +F Sbjct: 547 IVKSPCIEQF 556 >gi|21245124 adenosine deaminase domain containing 1 (testis-specific) isoform 1 [Homo sapiens] Length = 576 Score = 187 bits (474), Expect = 4e-47 Identities = 153/490 (31%), Positives = 240/490 (48%), Gaps = 54/490 (11%) Query: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259 +++ + +GP F F A +DG+ G +K E++ AA AL + QL+ PE Sbjct: 113 DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 169 Query: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304 +TS PP L+ L+ + + +E R + +V F+ L+ RS Y Sbjct: 170 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 229 Query: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364 ++A I+ER +++VA+GTG + ++ G+ LHD Sbjct: 230 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 270 Query: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424 H +V ARR+LLR+ +RQLLL P E+S+ +P TLK + + LY++ Sbjct: 271 THAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQL 329 Query: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481 PKG+A+ + L P S + + L V G++ Y P + +S+SDK Sbjct: 330 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 388 Query: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540 L RW VLG+ GALL+H + P+Y +S+++ D +C D L AI R +D L LP Sbjct: 389 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 446 Query: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596 Y+ H+ P P + + + LSLNW+ GD +E+VD +G++ + + + Sbjct: 447 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 505 Query: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654 SRLCKA+ L F+ A+ K LL TY AAK + YQEA+ +L L Q G G+W Sbjct: 506 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 564 Query: 655 PSK-PLVGKF 663 K P + +F Sbjct: 565 IVKSPCIEQF 574 >gi|226529650 adenosine deaminase domain containing 1 (testis-specific) isoform 2 [Homo sapiens] Length = 565 Score = 167 bits (423), Expect = 3e-41 Identities = 147/490 (30%), Positives = 232/490 (47%), Gaps = 65/490 (13%) Query: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259 +++ + +GP F F A +DG+ G +K E++ AA AL + QL+ PE Sbjct: 113 DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 169 Query: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304 +TS PP L+ L+ + + +E R + +V F+ L+ RS Y Sbjct: 170 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 229 Query: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364 ++A I+ER +++VA+GTG + ++ G+ LHD Sbjct: 230 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 270 Query: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424 H +V ARR+LL P E+S+ +P TLK + + LY++ Sbjct: 271 THAVVTARRSLL-----------SKNPAMMEKSIFCTEPTSNL-LTLKQNINICLYMNQL 318 Query: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481 PKG+A+ + L P S + + L V G++ Y P + +S+SDK Sbjct: 319 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 377 Query: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540 L RW VLG+ GALL+H + P+Y +S+++ D +C D L AI R +D L LP Sbjct: 378 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 435 Query: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596 Y+ H+ P P + + + LSLNW+ GD +E+VD +G++ + + + Sbjct: 436 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 494 Query: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654 SRLCKA+ L F+ A+ K LL TY AAK + YQEA+ +L L Q G G+W Sbjct: 495 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 553 Query: 655 PSK-PLVGKF 663 K P + +F Sbjct: 554 IVKSPCIEQF 563 >gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo sapiens] Length = 701 Score = 137 bits (345), Expect = 3e-32 Identities = 140/465 (30%), Positives = 211/465 (45%), Gaps = 59/465 (12%) Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276 F +S +DG G+ +K AK +AA SAL I N QT SR P+ ++ Sbjct: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317 Query: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334 L + LV F L D S A + +AGV++ G T++ A Sbjct: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366 Query: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393 K++++ TG+ C G ++ G L+DCH +I+RR+LLRFL+ QL L Sbjct: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421 Query: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEGGLPHSPPMRLQ 451 K + G F LK V HLYIS +P G AR I+ P P E P + + Sbjct: 422 KRSIFQKSERGG---FRLKENVQFHLYISTSPCGDAR-IFSPHEPILEEPADRHPNRKAR 477 Query: 452 AHVLGQLKPVCYVAPSLCDTHVGC------------LSASDKLARWAVLGLGGALLAHLV 499 + +++ P + + +S SDK+ARW V+G+ G+LL+ V Sbjct: 478 GQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFV 537 Query: 500 SPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEP 559 P+Y +S+IL H LSRA++ R + ++ LPP Y L +G A + Sbjct: 538 EPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--EDLPPLYTLNK-PLLSGISNAEAR- 590 Query: 560 TPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCK----ASFLRAFHQAARA 615 P S+NW++GD IEV++ TG+ + LG SRLCK ++R + Sbjct: 591 QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LGRASRLCKHALYCRWMRVHGKVPSH 646 Query: 616 VGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAWPSKP 658 + + + Y +K A YQ A+ +L + GLGAW KP Sbjct: 647 LLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKP 691 >gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] Length = 739 Score = 130 bits (327), Expect = 4e-30 Identities = 131/463 (28%), Positives = 205/463 (44%), Gaps = 60/463 (12%) Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276 F ++ +DG G+ SK A+ QAA +AL + +P + R P+ ++ Sbjct: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADS 364 Query: 277 ILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVK 336 I + LV+ F + + +P A +AG+++ +G Sbjct: 365 I-------SQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQA------------- 404 Query: 337 EIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKE 395 ++VAL +G+ C +G L G ++DCH V+ARRA L FL+ QL L + E Sbjct: 405 ---QVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSE 461 Query: 396 QSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPM--RLQAH 453 +S+ G + L+ + HLY+S +P G AR ++ P L S + + + H Sbjct: 462 RSIFVRLKEGG--YRLRENILFHLYVSTSPCGDAR-LHSPYEITTDLHSSKHLVRKFRGH 518 Query: 454 VLGQLKP----VCYVAPSLCDTHVGCL--------SASDKLARWAVLGLGGALLAHLVSP 501 + +++ V PS T G L S +DK+ARW VLGL GALL+H V P Sbjct: 519 LRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578 Query: 502 LYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTP 561 +Y S+++ S H L+R + R + G P R L +G A + P Sbjct: 579 VYLQSIVVG-SLHHTGHLARVMSHR-----MEGVGQLPASYRHNRPLLSGVSDAEAR-QP 631 Query: 562 DTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCK----ASFLRAFHQAARAVG 617 S+NW +G +E+++ TGR + G PSRLCK A + R + + + Sbjct: 632 GKSPPFSMNWVVGSADLEIINATTGR----RSCGGPSRLCKHVLSARWARLYGRLSTRTP 687 Query: 618 KPYLLALKTYEAAKAG--PYQEARRQLSLLLDQQGLGAWPSKP 658 P Y AK G YQ ++QL + GLG W KP Sbjct: 688 SPGDTP-SMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKP 729 >gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo sapiens] Length = 674 Score = 126 bits (317), Expect = 6e-29 Identities = 137/446 (30%), Positives = 202/446 (45%), Gaps = 67/446 (15%) Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276 F +S +DG G+ +K AK +AA SAL I N QT SR P+ ++ Sbjct: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317 Query: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334 L + LV F L D S A + +AGV++ G T++ A Sbjct: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366 Query: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393 K++++ TG+ C G ++ G L+DCH +I+RR+LLRFL+ QL L Sbjct: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421 Query: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEGGLPHSPPMRLQ 451 K + G F LK V HLYIS +P G AR I+ P P E P + + Sbjct: 422 KRSIFQKSERGG---FRLKENVQFHLYISTSPCGDAR-IFSPHEPILEEPADRHPNRKAR 477 Query: 452 AHVLGQLKPVCYVAPSLCDTHVGC------------LSASDKLARWAVLGLGGALLAHLV 499 + +++ P + + +S SDK+ARW V+G+ G+LL+ V Sbjct: 478 GQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFV 537 Query: 500 SPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEP 559 P+Y +S+IL H LSRA++ R + ++ LPP Y L +G A + Sbjct: 538 EPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--EDLPPLYTLNK-PLLSGISNAEAR- 590 Query: 560 TPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCK-ASFLR--------AFH 610 P S+NW++GD IEV++ TG+ + LG SRLCK A + R H Sbjct: 591 QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LGRASRLCKHALYCRWMRVHGKVPSH 646 Query: 611 QAARAVGKPYL-----LALKTYEAAK 631 + KP + LA K Y+AAK Sbjct: 647 LLRSKITKPNVYHESKLAAKEYQAAK 672 >gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sapiens] Length = 1181 Score = 108 bits (271), Expect = 1e-23 Identities = 128/476 (26%), Positives = 198/476 (41%), Gaps = 58/476 (12%) Query: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265 V++ GP F A++ G PA A+SK + KQ+AA +AL + + E E + Sbjct: 728 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 787 Query: 266 RPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSC 325 P + I RC F+ L + P + +A +I+++ Sbjct: 788 LPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKILAAIIMKKD-------- 832 Query: 326 TEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLL 384 +++ +V+LGTG+ C G L G+ ++DCH +I+RR +RFL+ +L+ Sbjct: 833 ---------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELM 883 Query: 385 LATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARDIYLPPT 437 + + + S+ P G G +K V HLYIS P G + D + T Sbjct: 884 ---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 939 Query: 438 SEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASDKLARWA 486 P +P +L+ V + + + T G +S SDK+ RW Sbjct: 940 ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 999 Query: 487 VLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPPPYVRTA 545 VLGL GALL H + P+Y S+ L L+RAI R D S L P++ Sbjct: 1000 VLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRHPFI--V 1056 Query: 546 LHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPPSRLCKA 603 H G + S+ + S+NW L D +E++D G V + SR+ K Sbjct: 1057 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNELSRVSKK 1114 Query: 604 SFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPSKP 658 + F + + LL L EA KA Y+ A+ L G G W SKP Sbjct: 1115 NIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKP 1170 >gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sapiens] Length = 1200 Score = 108 bits (271), Expect = 1e-23 Identities = 128/476 (26%), Positives = 198/476 (41%), Gaps = 58/476 (12%) Query: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265 V++ GP F A++ G PA A+SK + KQ+AA +AL + + E E + Sbjct: 747 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 806 Query: 266 RPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSC 325 P + I RC F+ L + P + +A +I+++ Sbjct: 807 LPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKILAAIIMKKD-------- 851 Query: 326 TEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLL 384 +++ +V+LGTG+ C G L G+ ++DCH +I+RR +RFL+ +L+ Sbjct: 852 ---------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELM 902 Query: 385 LATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARDIYLPPT 437 + + + S+ P G G +K V HLYIS P G + D + T Sbjct: 903 ---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 958 Query: 438 SEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASDKLARWA 486 P +P +L+ V + + + T G +S SDK+ RW Sbjct: 959 ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 1018 Query: 487 VLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPPPYVRTA 545 VLGL GALL H + P+Y S+ L L+RAI R D S L P++ Sbjct: 1019 VLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRHPFI--V 1075 Query: 546 LHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPPSRLCKA 603 H G + S+ + S+NW L D +E++D G V + SR+ K Sbjct: 1076 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNELSRVSKK 1133 Query: 604 SFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPSKP 658 + F + + LL L EA KA Y+ A+ L G G W SKP Sbjct: 1134 NIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKP 1189 >gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sapiens] Length = 931 Score = 105 bits (261), Expect = 2e-22 Identities = 129/495 (26%), Positives = 202/495 (40%), Gaps = 70/495 (14%) Query: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265 V++ GP F A++ G PA A+SK + KQ+AA +AL + + E E + Sbjct: 452 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 511 Query: 266 RPPLAPLSVENIL-------------------THEQRCAALVSAGFDLLLDERSPYWACK 306 P+ S+ + T + A L F+ L + P + Sbjct: 512 VTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 571 Query: 307 GTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDC 365 +A +I+++ +++ +V+LGTG+ C G L G+ ++DC Sbjct: 572 KILAAIIMKKD-----------------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDC 614 Query: 366 HGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTP 425 H +I+RR +RFL+ +L+ + + + S+ P G G +K V HLYIS P Sbjct: 615 HAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAP 670 Query: 426 KG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG- 474 G + D + T P +P +L+ V + + + T G Sbjct: 671 CGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGI 730 Query: 475 -------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRP 527 +S SDK+ RW VLGL GALL H + P+Y S+ L L+RAI R Sbjct: 731 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRV 789 Query: 528 CLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVA 584 D S L P++ H G + S+ + S+NW L D +E++D Sbjct: 790 TRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGT 847 Query: 585 TGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLS 643 G V + SR+ K + F + + LL L EA KA Y+ A+ Sbjct: 848 RGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 905 Query: 644 LLLDQQGLGAWPSKP 658 L G G W SKP Sbjct: 906 KGLKDMGYGNWISKP 920 >gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sapiens] Length = 1226 Score = 105 bits (261), Expect = 2e-22 Identities = 129/495 (26%), Positives = 202/495 (40%), Gaps = 70/495 (14%) Query: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265 V++ GP F A++ G PA A+SK + KQ+AA +AL + + E E + Sbjct: 747 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 806 Query: 266 RPPLAPLSVENIL-------------------THEQRCAALVSAGFDLLLDERSPYWACK 306 P+ S+ + T + A L F+ L + P + Sbjct: 807 VTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 866 Query: 307 GTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDC 365 +A +I+++ +++ +V+LGTG+ C G L G+ ++DC Sbjct: 867 KILAAIIMKKD-----------------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDC 909 Query: 366 HGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTP 425 H +I+RR +RFL+ +L+ + + + S+ P G G +K V HLYIS P Sbjct: 910 HAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAP 965 Query: 426 KG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG- 474 G + D + T P +P +L+ V + + + T G Sbjct: 966 CGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGI 1025 Query: 475 -------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRP 527 +S SDK+ RW VLGL GALL H + P+Y S+ L L+RAI R Sbjct: 1026 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRV 1084 Query: 528 CLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVA 584 D S L P++ H G + S+ + S+NW L D +E++D Sbjct: 1085 TRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGT 1142 Query: 585 TGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLS 643 G V + SR+ K + F + + LL L EA KA Y+ A+ Sbjct: 1143 RGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200 Query: 644 LLLDQQGLGAWPSKP 658 L G G W SKP Sbjct: 1201 KGLKDMGYGNWISKP 1215 >gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo sapiens] Length = 741 Score = 83.6 bits (205), Expect = 5e-16 Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 17/189 (8%) Query: 476 LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGP 535 +S SDK+ARW V+G+ G+LL+ V P+Y +S+IL H LSRA++ R + ++ Sbjct: 554 MSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--E 608 Query: 536 CLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALG 595 LPP Y L +G A + P S+NW++GD IEV++ TG+ + LG Sbjct: 609 DLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LG 662 Query: 596 PPSRLCK----ASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQ 649 SRLCK ++R + + + + Y +K A YQ A+ +L + Sbjct: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKA 722 Query: 650 GLGAWPSKP 658 GLGAW KP Sbjct: 723 GLGAWVEKP 731 Score = 73.6 bits (179), Expect = 6e-13 Identities = 75/229 (32%), Positives = 105/229 (45%), Gaps = 30/229 (13%) Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276 F +S +DG G+ +K AK +AA SAL I N QT SR P+ ++ Sbjct: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317 Query: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334 L + LV F L D S A + +AGV++ G T++ A Sbjct: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366 Query: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393 K++++ TG+ C G ++ G L+DCH +I+RR+LLRFL+ QL L Sbjct: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421 Query: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEG 440 K + G F LK V HLYIS +P G AR I+ P P EG Sbjct: 422 KRSIFQKSERG---GFRLKENVQFHLYISTSPCGDAR-IFSPHEPILEG 466 >gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo sapiens] Length = 714 Score = 73.6 bits (179), Expect = 6e-13 Identities = 75/229 (32%), Positives = 105/229 (45%), Gaps = 30/229 (13%) Query: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276 F +S +DG G+ +K AK +AA SAL I N QT SR P+ ++ Sbjct: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317 Query: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334 L + LV F L D S A + +AGV++ G T++ A Sbjct: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366 Query: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393 K++++ TG+ C G ++ G L+DCH +I+RR+LLRFL+ QL L Sbjct: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421 Query: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEG 440 K + G F LK V HLYIS +P G AR I+ P P EG Sbjct: 422 KRSIFQKSERG---GFRLKENVQFHLYISTSPCGDAR-IFSPHEPILEG 466 Score = 72.8 bits (177), Expect = 1e-12 Identities = 61/170 (35%), Positives = 88/170 (51%), Gaps = 25/170 (14%) Query: 476 LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGP 535 +S SDK+ARW V+G+ G+LL+ V P+Y +S+IL H LSRA++ R + ++ Sbjct: 554 MSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--E 608 Query: 536 CLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALG 595 LPP Y L +G A + P S+NW++GD IEV++ TG+ + LG Sbjct: 609 DLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LG 662 Query: 596 PPSRLCK-ASFLR--------AFHQAARAVGKPYL-----LALKTYEAAK 631 SRLCK A + R H + KP + LA K Y+AAK Sbjct: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712 >gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] Length = 502 Score = 43.1 bits (100), Expect = 8e-04 Identities = 31/91 (34%), Positives = 47/91 (51%), Gaps = 6/91 (6%) Query: 340 KLVALGTGSSCCA-GWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSV 398 ++V++GTG+ C + +G L+D H VIARR+ R+L QL LA KE S+ Sbjct: 60 EIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQLAA----TLKEDSI 115 Query: 399 LAPQPGPGPPFTLKPRVFLHLYISNTPKGAA 429 P G + L+ + + S+TP G A Sbjct: 116 FVPGTQKG-VWKLRRDLIFVFFSSHTPCGDA 145 Score = 43.1 bits (100), Expect = 8e-04 Identities = 20/49 (40%), Positives = 32/49 (65%), Gaps = 1/49 (2%) Query: 476 LSASDKLARWAVLGLGGALLAHLV-SPLYSTSLILADSCHDPPTLSRAI 523 +S SDK+ARW VLG GALL HL+ P+Y +++++ + + RA+ Sbjct: 297 MSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRAL 345 >gi|31324577 molecule interacting with Rab13 [Homo sapiens] Length = 863 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 19/121 (15%) Query: 2 ASASQGADDDGSRR----------KPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPAT 51 +SA GA+ DG + KPR+ LQ P RP PA +++ PAP T Sbjct: 259 SSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPT 318 Query: 52 YRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDP 111 R Q +++ AG L R E + K P P G P KDP Sbjct: 319 PRPRSSLQQENLVEQ------AGSSSLVNGRLHE---LPVPKPRGTPKPSEGTPAPRKDP 369 Query: 112 P 112 P Sbjct: 370 P 370 >gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo sapiens] Length = 1336 Score = 38.5 bits (88), Expect = 0.020 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 10/93 (10%) Query: 29 PRPWRPLPAQAQSAWGPAPAPATY--RAEGGWPQVSVLRDSGPGAGAGVGELGAARAW-- 84 P P +PLP+ A A PAP PA + R + + +GP GAG+ + G R + Sbjct: 909 PPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLAD-GFHRYYGP 967 Query: 85 ---ENLGEQMGKAPRVPVPPAG--LSLPLKDPP 112 + LG +G+A P AG LS P PP Sbjct: 968 IEPQGLGLGLGEARAAPRGAAGRPLSPPAAQPP 1000 >gi|239753839 PREDICTED: hypothetical protein [Homo sapiens] Length = 257 Score = 38.1 bits (87), Expect = 0.026 Identities = 33/101 (32%), Positives = 40/101 (39%), Gaps = 7/101 (6%) Query: 12 GSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPA--TYRAEGGWPQVSVLRDSGP 69 GS+ P L + W P PA+A A G PA RA G + R P Sbjct: 64 GSQEHPGAGGPLCFPARSAAWGP-PARASRAAGRRAGPAGPPCRAPGRGRAAATRRSPAP 122 Query: 70 GAG----AGVGELGAARAWENLGEQMGKAPRVPVPPAGLSL 106 G AGV G A A + G + A R+P P G SL Sbjct: 123 GTARGSPAGVERAGGATAASSAGTRSVPARRLPPPCGGTSL 163 >gi|209862845 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 isoform 1 [Homo sapiens] Length = 964 Score = 37.0 bits (84), Expect = 0.059 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 6/76 (7%) Query: 29 PRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLG 88 PRP P P PAP+P T+ ++ P SV R GPG GA G G R E Sbjct: 125 PRPPPPRPGMHSPPPRPAPSPGTWESQ---PARSV-RLGGPGGGA--GGAGGGRVLECPS 178 Query: 89 EQMGKAPRVPVPPAGL 104 ++ P PPA L Sbjct: 179 IRITSISPTPEPPAAL 194 >gi|27886563 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 isoform 2 [Homo sapiens] Length = 902 Score = 37.0 bits (84), Expect = 0.059 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 6/76 (7%) Query: 29 PRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLG 88 PRP P P PAP+P T+ ++ P SV R GPG GA G G R E Sbjct: 62 PRPPPPRPGMHSPPPRPAPSPGTWESQ---PARSV-RLGGPGGGA--GGAGGGRVLECPS 115 Query: 89 EQMGKAPRVPVPPAGL 104 ++ P PPA L Sbjct: 116 IRITSISPTPEPPAAL 131 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 36.6 bits (83), Expect = 0.076 Identities = 39/123 (31%), Positives = 48/123 (39%), Gaps = 24/123 (19%) Query: 20 AASLQI----SPQPRPWRPLPAQAQSAWG-----PAPAPATYRAEGGWPQVSV------- 63 A +LQI SP P P P PA A SA G P P GG P+ V Sbjct: 822 ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881 Query: 64 -------LRDSGPGAGAGVGELGAARAWENLGEQM-GKAPRVPVPPAGLSLPLKDPPASQ 115 LR G GA LG + + L + G+A VP P +GL ++ S Sbjct: 882 SLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSL 941 Query: 116 AVS 118 A S Sbjct: 942 AAS 944 >gi|45433499 zinc finger, DHHC-type containing 18 [Homo sapiens] Length = 388 Score = 35.8 bits (81), Expect = 0.13 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 11/68 (16%) Query: 20 AASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELG 79 AA L SP R RP PA + + GP PAP A W SG G+G+G G LG Sbjct: 13 AAPLPASPGAR--RPGPAASPTP-GPGPAPPAAPAPPRWSS------SGSGSGSGSGSLG 63 Query: 80 --AARAWE 85 R WE Sbjct: 64 RRPRRKWE 71 >gi|122937321 UNC homeobox [Homo sapiens] Length = 531 Score = 35.4 bits (80), Expect = 0.17 Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 10/108 (9%) Query: 27 PQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQV------SVLRDSGPGAGAGVGELGA 80 PQPRP RP A S A A R G P+ S+L DS P A A Sbjct: 295 PQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAA 354 Query: 81 ARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLG 128 A A + + APR + L P +Q + L AA G Sbjct: 355 AAAGLDFAPGLPCAPRTLIGKGHFLL----YPITQPLGFLVPQAALKG 398 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 35.4 bits (80), Expect = 0.17 Identities = 30/88 (34%), Positives = 37/88 (42%), Gaps = 3/88 (3%) Query: 35 LPAQAQSAWGPAPAPATYRA--EGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMG 92 LP Q Q A PAPAP T A G P S+ PG G++ AA A + Sbjct: 832 LPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTN-GKVLAATAPTPGIPILQ 890 Query: 93 KAPRVPVPPAGLSLPLKDPPASQAVSLL 120 P P P A P++ PP + LL Sbjct: 891 SVPSAPPPKAQSVSPVQAPPPGGSAQLL 918 >gi|13375642 kringle-containing transmembrane protein 2 isoform b precursor [Homo sapiens] Length = 420 Score = 35.4 bits (80), Expect = 0.17 Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 13/111 (11%) Query: 236 KTEAKQQAALSALCY--IRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFD 293 +++A+ A AL Y ++ E+PE+P+ S++ P APL N+ + A + G Sbjct: 309 RSDARGHAQGFALTYRGLQDAAEDPEAPEGSAQTPAAPLDGANVSCSPRPGAPPAAIGGA 368 Query: 294 LL-LDERSP-YWACKGT-----VAGVILERGWAVSAPSCTE----IPRARG 333 + L E+ P W G + G GW AP T +PRA G Sbjct: 369 VCWLREKGPRRWGLPGAPGEAGLCGTNSPEGWPCPAPPGTPRLRVLPRATG 419 >gi|7662010 zinc finger protein 516 [Homo sapiens] Length = 1163 Score = 35.0 bits (79), Expect = 0.22 Identities = 35/131 (26%), Positives = 49/131 (37%), Gaps = 18/131 (13%) Query: 7 GADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPA--PAPATYRAEGGWPQVS-- 62 GA G KPR AS +P+PA + + P P G P + Sbjct: 898 GAATQGPLAKPRQEASS---------KPVPAPGGGGFSRSATPTPTVIARAGAQPSANSK 948 Query: 63 -VLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLS----LPLKDPPASQAV 117 V + P AGAG A ++L + P+ P P G LP ++PP+ A Sbjct: 949 PVEKFGVPPAGAGFAPTNKHSAPDSLKAKFSAQPQGPPPAKGEGGAPPLPPREPPSKAAQ 1008 Query: 118 SLLTEYAASLG 128 L T + G Sbjct: 1009 ELRTLATCAAG 1019 >gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] Length = 1192 Score = 33.9 bits (76), Expect = 0.50 Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 14/93 (15%) Query: 48 APATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLP 107 A AT A GG + + G GAG G G + + + + P PPAG P Sbjct: 236 AAATAAAAGGGGSTA---STSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPP 292 Query: 108 LKDPPASQAVSLLTEYAASLGIFLLFREDQPPG 140 L PP + +T +A QPPG Sbjct: 293 LTLPPTPSPATAVTAASA-----------QPPG 314 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 33.9 bits (76), Expect = 0.50 Identities = 18/43 (41%), Positives = 21/43 (48%) Query: 34 PLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVG 76 P+PA A A GP PAPA G ++ GPG G G G Sbjct: 139 PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181 Score = 30.8 bits (68), Expect = 4.2 Identities = 30/94 (31%), Positives = 36/94 (38%), Gaps = 10/94 (10%) Query: 27 PQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWEN 86 P P P PA AQ+ APA A GG V GPGA A G Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG--PAGVSGQPGPGAAAAAPAPG------- 341 Query: 87 LGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120 + + K PPA +L PAS A S++ Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASG-PASTAASMV 374 >gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens] Length = 773 Score = 33.9 bits (76), Expect = 0.50 Identities = 17/36 (47%), Positives = 22/36 (61%) Query: 213 PCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSAL 248 P PF S +DGV +GTA+SK AK +AA + L Sbjct: 538 PSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATL 573 >gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sapiens] Length = 735 Score = 33.9 bits (76), Expect = 0.50 Identities = 38/157 (24%), Positives = 61/157 (38%), Gaps = 15/157 (9%) Query: 27 PQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWEN 86 P+P P P P + + A P++ A + + L+ P + V LG A+ E+ Sbjct: 36 PEPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWV--LGGAKPAED 93 Query: 87 L---------GEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQ 137 GE G+ P+P P +PP Q S +E A G Sbjct: 94 TSLGPGVPGTGEPAGEIWYNPIPEEDPRPPAPEPPGPQPGSAESEGLAPQGA----APAS 149 Query: 138 PPGKVFKYRAPGGEELKAMCLWQVEVLRAFLLRTGWR 174 PP K + ++PG ++ + ++ LR L G R Sbjct: 150 PPTKASRTKSPGPARRLSIKMKKLPELRRRLSLRGPR 186 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,037,967 Number of Sequences: 37866 Number of extensions: 1846920 Number of successful extensions: 7316 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 130 Number of HSP's that attempted gapping in prelim test: 7030 Number of HSP's gapped (non-prelim): 368 length of query: 665 length of database: 18,247,518 effective HSP length: 109 effective length of query: 556 effective length of database: 14,120,124 effective search space: 7850788944 effective search space used: 7850788944 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.