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Search of human proteins with 223718222
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223718222 fibronectin type III and SPRY domain containing
1-like isoform 3 [Homo sapiens]
(530 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223718222 fibronectin type III and SPRY domain containing 1-l... 1070 0.0
gi|89886468 fibronectin type III and SPRY domain containing 1-li... 997 0.0
gi|13236585 fibronectin type III and SPRY domain containing 1 [H... 612 e-175
gi|13994289 fibronectin type III and SPRY domain containing 1-li... 216 3e-56
gi|148833499 midline 1 [Homo sapiens] 214 2e-55
gi|4557753 midline 1 [Homo sapiens] 214 2e-55
gi|15451852 midline 1 [Homo sapiens] 214 2e-55
gi|223890259 midline 2 isoform 2 [Homo sapiens] 202 8e-52
gi|223890257 midline 2 isoform 1 [Homo sapiens] 191 1e-48
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 118 2e-26
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 114 2e-25
gi|134288906 tripartite motif-containing 67 [Homo sapiens] 108 1e-23
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] 103 3e-22
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 99 1e-20
gi|46409324 SPRY domain containing 4 [Homo sapiens] 84 4e-16
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] 82 9e-16
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 82 1e-15
gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 80 4e-15
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 80 5e-15
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 77 5e-14
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 77 5e-14
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 77 5e-14
gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens] 71 2e-12
gi|22749269 ring finger protein 129 [Homo sapiens] 69 8e-12
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 69 1e-11
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 67 4e-11
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ... 67 5e-11
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ... 67 5e-11
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ... 67 5e-11
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens] 62 1e-09
>gi|223718222 fibronectin type III and SPRY domain containing 1-like
isoform 3 [Homo sapiens]
Length = 530
Score = 1070 bits (2766), Expect = 0.0
Identities = 530/530 (100%), Positives = 530/530 (100%)
Query: 1 MDSQKYCFKENENVTVDKACFLISNITIGPESINLQQEALQRIISTLANKNDEIQNFIDT 60
MDSQKYCFKENENVTVDKACFLISNITIGPESINLQQEALQRIISTLANKNDEIQNFIDT
Sbjct: 1 MDSQKYCFKENENVTVDKACFLISNITIGPESINLQQEALQRIISTLANKNDEIQNFIDT 60
Query: 61 LHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCN 120
LHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCN
Sbjct: 61 LHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCN 120
Query: 121 NALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFRLSLKPKVSDNMTHLMVD 180
NALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFRLSLKPKVSDNMTHLMVD
Sbjct: 121 NALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFRLSLKPKVSDNMTHLMVD 180
Query: 181 FSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFD 240
FSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFD
Sbjct: 181 FSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFD 240
Query: 241 GLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKAL 300
GLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKAL
Sbjct: 241 GLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKAL 300
Query: 301 NFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAV 360
NFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAV
Sbjct: 301 NFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAV 360
Query: 361 RGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW 420
RGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW
Sbjct: 361 RGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW 420
Query: 421 CIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKF 480
CIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKF
Sbjct: 421 CIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKF 480
Query: 481 TQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSENGMTGSASSLNNVVTQ 530
TQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSENGMTGSASSLNNVVTQ
Sbjct: 481 TQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSENGMTGSASSLNNVVTQ 530
>gi|89886468 fibronectin type III and SPRY domain containing 1-like
isoform 1 [Homo sapiens]
Length = 498
Score = 997 bits (2578), Expect = 0.0
Identities = 494/495 (99%), Positives = 495/495 (100%)
Query: 36 QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95
Q+EALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE
Sbjct: 4 QKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 63
Query: 96 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 155
SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR
Sbjct: 64 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 123
Query: 156 VTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVT 215
VTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVT
Sbjct: 124 VTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVT 183
Query: 216 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 275
VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN
Sbjct: 184 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 243
Query: 276 FRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIK 335
FRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIK
Sbjct: 244 FRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIK 303
Query: 336 GKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDC 395
GKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDC
Sbjct: 304 GKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDC 363
Query: 396 KSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFC 455
KSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFC
Sbjct: 364 KSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFC 423
Query: 456 DFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSEN 515
DFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSEN
Sbjct: 424 DFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSEN 483
Query: 516 GMTGSASSLNNVVTQ 530
GMTGSASSLNNVVTQ
Sbjct: 484 GMTGSASSLNNVVTQ 498
>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
sapiens]
Length = 496
Score = 612 bits (1578), Expect = e-175
Identities = 299/492 (60%), Positives = 386/492 (78%), Gaps = 3/492 (0%)
Query: 36 QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95
Q+EAL++II TLA KN+EIQ+FI +L L V+ NS+ + +L+ EF SL+S+L+E+KE
Sbjct: 4 QREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKE 63
Query: 96 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 155
M+ IKQ++A ++ ELQ+Q++ C ALE+SEELLE A ++L + E+F +AA+QIKD
Sbjct: 64 GMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDG 123
Query: 156 VTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVT 215
VTMA AFRLSLK KVSDNM+HLMVDF+QERQMLQ LKFLPVP AP ID E LVADN VT
Sbjct: 124 VTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADNCVT 183
Query: 216 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 275
+ WRMP+ED+KIDH++LE+R+TNF+G PR+K+++ W +I+ I+ TEYTL+GLKFD KYMN
Sbjct: 184 LVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMKYMN 243
Query: 276 FRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIK 335
FRV+ACNKAVAGE+S+PVTLET A F LD S+SH NL+V+D VEWD GGK Q+ K +
Sbjct: 244 FRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDIKAR 303
Query: 336 GKENKGRSGTP--SPKR-TSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQ 392
K+ KGR+ +P SP R T R P+ RG RDRFT ESYTVLGDT I+ G+HYWEV+ +
Sbjct: 304 EKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRYE 363
Query: 393 KDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIG 452
D K++ VGVAY++LG+F+QLGKT SWC+HVNNWLQ +F AKH NKVK LD VP+ +G
Sbjct: 364 PDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPDCLG 423
Query: 453 VFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQK 512
V CDF G LSFY+A +KQ+L++FKT+FTQP+LP F VWCG ++TG+QVPSAVR LQK
Sbjct: 424 VHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQK 483
Query: 513 SENGMTGSASSL 524
+ + S +SL
Sbjct: 484 RGSATSSSNTSL 495
>gi|13994289 fibronectin type III and SPRY domain containing 1-like
isoform 2 [Homo sapiens]
Length = 145
Score = 216 bits (551), Expect = 3e-56
Identities = 111/112 (99%), Positives = 112/112 (100%)
Query: 36 QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95
Q+EALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE
Sbjct: 4 QKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 63
Query: 96 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSK 147
SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSK
Sbjct: 64 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSK 115
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 214 bits (545), Expect = 2e-55
Identities = 148/480 (30%), Positives = 244/480 (50%), Gaps = 54/480 (11%)
Query: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
++ L+ ++ L +N E++ + L T + V+ N+S ++L EE D L I+ + ++
Sbjct: 220 KQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQI 279
Query: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
+ IK+ + + ++L QI+ C +E S L+ A SL + F + A+ I +RV
Sbjct: 280 IGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERV 339
Query: 157 TMASAFRLSLKPKV--SDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 214
+MA+A L P++ +D +DFS+E+++L+ L +L P P I C + +++
Sbjct: 340 SMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTI 399
Query: 215 TVAWRMPEEDNKIDHFILEHRKTNFDGLPRV----KDERCWEIIDNIKGTEYTLSGLKFD 270
TV W +E + + + E + T F G V W I+ NIK YT+ GL+
Sbjct: 400 TVHWTSDDEFSVVSY---ELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSG 456
Query: 271 SKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKV--EDTCVEWDPTGGK 328
+KY+ F V+A N+A S+P L+T + F LD S+H LKV ++ VE D + K
Sbjct: 457 TKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSK 514
Query: 329 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE-SYTVLGDTAIESGQHYW 387
+S TP +RFT + SY V G+ I+SG+HYW
Sbjct: 515 -------------KSHTP------------------ERFTSQGSYGVAGNVFIDSGRHYW 543
Query: 388 EVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW--CIHVNNWLQNTFAAKHNNKVKALDV 445
EV Y++G+AYK+ K + +GK + SW C NNW+ +HN+K ++
Sbjct: 544 EV-VISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV-----VRHNSKEIPIEP 597
Query: 446 TVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVP 504
++G+ D+D G ++FYDA + LY+F F QPV P F VW L++ TG+ +P
Sbjct: 598 APHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIP 657
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 214 bits (545), Expect = 2e-55
Identities = 148/480 (30%), Positives = 244/480 (50%), Gaps = 54/480 (11%)
Query: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
++ L+ ++ L +N E++ + L T + V+ N+S ++L EE D L I+ + ++
Sbjct: 220 KQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQI 279
Query: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
+ IK+ + + ++L QI+ C +E S L+ A SL + F + A+ I +RV
Sbjct: 280 IGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERV 339
Query: 157 TMASAFRLSLKPKV--SDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 214
+MA+A L P++ +D +DFS+E+++L+ L +L P P I C + +++
Sbjct: 340 SMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTI 399
Query: 215 TVAWRMPEEDNKIDHFILEHRKTNFDGLPRV----KDERCWEIIDNIKGTEYTLSGLKFD 270
TV W +E + + + E + T F G V W I+ NIK YT+ GL+
Sbjct: 400 TVHWTSDDEFSVVSY---ELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSG 456
Query: 271 SKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKV--EDTCVEWDPTGGK 328
+KY+ F V+A N+A S+P L+T + F LD S+H LKV ++ VE D + K
Sbjct: 457 TKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSK 514
Query: 329 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE-SYTVLGDTAIESGQHYW 387
+S TP +RFT + SY V G+ I+SG+HYW
Sbjct: 515 -------------KSHTP------------------ERFTSQGSYGVAGNVFIDSGRHYW 543
Query: 388 EVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW--CIHVNNWLQNTFAAKHNNKVKALDV 445
EV Y++G+AYK+ K + +GK + SW C NNW+ +HN+K ++
Sbjct: 544 EV-VISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV-----VRHNSKEIPIEP 597
Query: 446 TVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVP 504
++G+ D+D G ++FYDA + LY+F F QPV P F VW L++ TG+ +P
Sbjct: 598 APHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIP 657
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 214 bits (545), Expect = 2e-55
Identities = 148/480 (30%), Positives = 244/480 (50%), Gaps = 54/480 (11%)
Query: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
++ L+ ++ L +N E++ + L T + V+ N+S ++L EE D L I+ + ++
Sbjct: 220 KQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQI 279
Query: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
+ IK+ + + ++L QI+ C +E S L+ A SL + F + A+ I +RV
Sbjct: 280 IGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERV 339
Query: 157 TMASAFRLSLKPKV--SDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 214
+MA+A L P++ +D +DFS+E+++L+ L +L P P I C + +++
Sbjct: 340 SMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTI 399
Query: 215 TVAWRMPEEDNKIDHFILEHRKTNFDGLPRV----KDERCWEIIDNIKGTEYTLSGLKFD 270
TV W +E + + + E + T F G V W I+ NIK YT+ GL+
Sbjct: 400 TVHWTSDDEFSVVSY---ELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSG 456
Query: 271 SKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKV--EDTCVEWDPTGGK 328
+KY+ F V+A N+A S+P L+T + F LD S+H LKV ++ VE D + K
Sbjct: 457 TKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSK 514
Query: 329 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE-SYTVLGDTAIESGQHYW 387
+S TP +RFT + SY V G+ I+SG+HYW
Sbjct: 515 -------------KSHTP------------------ERFTSQGSYGVAGNVFIDSGRHYW 543
Query: 388 EVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW--CIHVNNWLQNTFAAKHNNKVKALDV 445
EV Y++G+AYK+ K + +GK + SW C NNW+ +HN+K ++
Sbjct: 544 EV-VISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV-----VRHNSKEIPIEP 597
Query: 446 TVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVP 504
++G+ D+D G ++FYDA + LY+F F QPV P F VW L++ TG+ +P
Sbjct: 598 APHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIP 657
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 202 bits (513), Expect = 8e-52
Identities = 141/486 (29%), Positives = 242/486 (49%), Gaps = 46/486 (9%)
Query: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
++ L+ ++ L +N E++N + L + V+ N++ ++L EE D L I+ + K+
Sbjct: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQM 299
Query: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
+ IK+ + K ++L Q++ C LE S L+ A L + F ++A+ I +RV
Sbjct: 300 IAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359
Query: 157 TMASAFRLSLKPKVS--DNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 214
MA+A L P ++ D + +DFS+E+++L+ L +L P P I C + +++
Sbjct: 360 AMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI 419
Query: 215 TVAWRMPEEDNKIDHFILEHR----KTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFD 270
TV W + +++ I + L++ + NF L D W I+ NIK YT+ GL+
Sbjct: 420 TVHW-ISDDEFSISSYELQYTIFTGQANFISLYNSVDS--WMIVPNIKQNHYTVHGLQSG 476
Query: 271 SKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQ 330
++Y+ F V+A N+A S+P L+T + F LD +H LK+ + ++ +
Sbjct: 477 TRYI-FIVKAINQA-GSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEK-----D 529
Query: 331 ESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGES-YTVLGDTAIESGQHYWEV 389
ES +K +S TP +RF+G Y G+ I+SG HYWEV
Sbjct: 530 ESSLK------KSHTP------------------ERFSGTGCYGAAGNIFIDSGCHYWEV 565
Query: 390 KAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVP- 448
Y++G+AYK+ K + +GK +SW N + F +HNNK +DV
Sbjct: 566 -VMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCN---SNFVVRHNNKEMLVDVPPHL 621
Query: 449 EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVR 508
+++GV D+D LSFYD + L++F F PV P F +W L + +G+ P +
Sbjct: 622 KRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFID 681
Query: 509 TLQKSE 514
++ E
Sbjct: 682 YPERQE 687
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 191 bits (485), Expect = 1e-48
Identities = 142/514 (27%), Positives = 243/514 (47%), Gaps = 72/514 (14%)
Query: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
++ L+ ++ L +N E++N + L + V+ N++ ++L EE D L I+ + K+
Sbjct: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQM 299
Query: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
+ IK+ + K ++L Q++ C LE S L+ A L + F ++A+ I +RV
Sbjct: 300 IAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359
Query: 157 TMASAFRLSLKPKVS--DNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 214
MA+A L P ++ D + +DFS+E+++L+ L +L P P I C + +++
Sbjct: 360 AMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI 419
Query: 215 TVAWRMPEEDNKIDHFILEHR----KTNF--------------------------DGLPR 244
TV W + +++ I + L++ + NF G PR
Sbjct: 420 TVHW-ISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPR 478
Query: 245 --VKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNF 302
W I+ NIK YT+ GL+ ++Y+ F V+A N+A S+P L+T + F
Sbjct: 479 GLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI-FIVKAINQA-GSRNSEPTRLKTNSQPF 536
Query: 303 NLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRG 362
LD +H LK+ + ++ + ES +K +S TP
Sbjct: 537 KLDPKMTHKKLKISNDGLQMEK-----DESSLK------KSHTP---------------- 569
Query: 363 SRDRFTGES-YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWC 421
+RF+G Y G+ I+SG HYWEV Y++G+AYK+ K + +GK +SW
Sbjct: 570 --ERFSGTGCYGAAGNIFIDSGCHYWEV-VMGSSTWYAIGIAYKSAPKNEWIGKNASSWV 626
Query: 422 IHVNNWLQNTFAAKHNNKVKALDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKF 480
N + F +HNNK +DV +++GV D+D LSFYD + L++F F
Sbjct: 627 FSRCN---SNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTF 683
Query: 481 TQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSE 514
PV P F +W L + +G+ P + ++ E
Sbjct: 684 ILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQE 717
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 118 bits (295), Expect = 2e-26
Identities = 115/497 (23%), Positives = 201/497 (40%), Gaps = 72/497 (14%)
Query: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
++ L + ++ + D +Q I L ++ + + E+ + L ++L+E + S
Sbjct: 271 KDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRAS 330
Query: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
++ I++ Q + L +QI + + L+ S L+ +A L + F +AA+Q+ +R+
Sbjct: 331 LLQAIEECQQERLARLSAQIQEHRSLLDGSG-LVGYAQEVLKETDQPCFVQAAKQLHNRI 389
Query: 157 TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTV 216
A+ + +P S + H +D +E ++L L FL VP+AP ID D + +
Sbjct: 390 ARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQ-IFL 448
Query: 217 AWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNF 276
WR+P H+ +E R+T+ +P W+ + ++GT L S Y+
Sbjct: 449 CWRLPPHSPPAWHYTVEFRRTD---VPAQPGPTRWQRREEVRGTSALLENPDTGSVYV-L 504
Query: 277 RVRACNKAVAGEYSDPVTLET---KALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESK 333
RVR CNKA GEYS+ V L T L+F LD+ W G +E
Sbjct: 505 RVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDS--------------RW----GASRERL 546
Query: 334 IKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTG---ESYTVLGDTAIESGQHYWEVK 390
K+ + P P + + TG VLGD A+ G+ YW
Sbjct: 547 AISKDQRAVRSVPG---------LPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACA 597
Query: 391 AQKDCKSYSVGVAYKT------------------------LGKFDQLGKTNTSWC---IH 423
VGV ++ G D + + + I
Sbjct: 598 VDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIG 657
Query: 424 VNNWLQNTFAAKH------NNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFK 477
+ L + A+ + + V +P ++G+ D++ G++SF DA S + L
Sbjct: 658 MGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECP 717
Query: 478 TKFTQPVLPGFMVWCGG 494
+ PV P F GG
Sbjct: 718 LDCSGPVCPAFCFIGGG 734
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 114 bits (285), Expect = 2e-25
Identities = 119/497 (23%), Positives = 210/497 (42%), Gaps = 76/497 (15%)
Query: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
+E L + I L K ++++ I L+ +K + N E F+ L+ +L+E K S
Sbjct: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316
Query: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
++ I + + + Q+Q+ + LEN+ L+ +A L + F + A+Q+ R+
Sbjct: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETDQSCFVQTAKQLHLRI 375
Query: 157 TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVP-KAPEIDPVECLVADNSVT 215
A+ S +P + +V+ S++ ++L L F PEI+ + V +N++
Sbjct: 376 QKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNAL- 434
Query: 216 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 275
+ W PE+D K D ++LE+RK N D DE W I+ + GT + L+ S Y
Sbjct: 435 INWHHPEKD-KADSYVLEYRKINRD------DEMSWNEIE-VCGTSKIIQDLENSSTYA- 485
Query: 276 FRVRACNKAVAGEYSDPVTLET---KALNFNLDN----SSSHLNLKVEDTCVEWDPTGGK 328
FRVRA ++ S + L T +F D ++ HL L ++ VE
Sbjct: 486 FRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVE------- 538
Query: 329 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWE 388
G + + +R VG +T Y ++GDT I G+H+W
Sbjct: 539 ---------SRAGFNLLLAAERIQVG-----------YYTSLDY-IIGDTGITKGKHFWA 577
Query: 389 VKAQKDCKSYSVGVAYK------------------------TLGKFDQLGKTNTSWCIHV 424
+ + VGVA G D ++ + + V
Sbjct: 578 FRVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTL-V 636
Query: 425 NNWLQNTFAAK---HNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFT 481
+Q F K +N+ + + +P IG+F D D G++ FYD + + LY + +
Sbjct: 637 TIGMQKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCS 696
Query: 482 QPVLPGF-MVWCGGLSL 497
+ P F ++ GG+ L
Sbjct: 697 HTLYPAFALMGSGGIQL 713
>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
Length = 783
Score = 108 bits (270), Expect = 1e-23
Identities = 111/445 (24%), Positives = 191/445 (42%), Gaps = 69/445 (15%)
Query: 40 LQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMIN 99
L + ++ +++K E + F+ L + L+ +QEN + + L + D+L L K ++
Sbjct: 351 LSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLT 410
Query: 100 CIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMA 159
+ +E+ K + + QI+ C L S L+E+ + +P F + + + RV ++
Sbjct: 411 KVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVS 470
Query: 160 SA--FRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLP----VPKAPEIDPVECLVADNS 213
+ +L+PKVS L +D Q + L F+ VP P + +C +NS
Sbjct: 471 QEQWVKGALEPKVSAEF-DLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNS 529
Query: 214 VTVAWRMPE-EDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSK 272
VT+AWRMP + +D +ILE L + E+ K T T+ GL F+S
Sbjct: 530 VTLAWRMPPFTHSPVDGYILE--------LDDGAGGQFREVYVG-KETLCTIDGLHFNST 580
Query: 273 YMNFRVRACNKAVAGEYSDPVTLETKALN-FNLDNSSSHLNLKVEDTCVEWDPTGGKGQE 331
Y N RV+A N + G YS V L+T + F D +S H ++ +
Sbjct: 581 Y-NARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIIL---------------- 623
Query: 332 SKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKA 391
N ++ T S + + VLG A G HYWE+
Sbjct: 624 ------SNDNQTATCS--------------------SYDDRVVLGTAAFSKGVHYWELHV 657
Query: 392 QK--DCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNN---WLQNTFAAKHNNKVKALDVT 446
+ + + GVA ++ K LGK + +W ++V+N W + H N+ + V
Sbjct: 658 DRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMH--CNSHTNRTEG-GVC 714
Query: 447 VPEKIGVFCDFDGGQLSFYDANSKQ 471
+GV D + L+F+ +Q
Sbjct: 715 KGATVGVLLDLNKHTLTFFINGQQQ 739
>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
Length = 710
Score = 103 bits (258), Expect = 3e-22
Identities = 111/457 (24%), Positives = 189/457 (41%), Gaps = 81/457 (17%)
Query: 35 LQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVK 94
L + L + ++ L+++ E + F+ L + ++ +QENS + L + D+L L+ K
Sbjct: 272 LHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRK 331
Query: 95 ESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKD 154
++ + +E K + ++ QIS C L + L+E+ + +P F + + +
Sbjct: 332 AQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIR 391
Query: 155 RV--TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFL------PVPKAPEIDPVE 206
RV T + +L P+++ + L +D S Q + L F+ PVP P + E
Sbjct: 392 RVHLTEDQWGKGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEE 450
Query: 207 CLVADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLS 265
C +NS T++W+ P D +ILE N V K T T+
Sbjct: 451 CCTHNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVG---------KETMCTVD 501
Query: 266 GLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALN-FNLDNSSSHLNLKVED-----TC 319
GL F+S Y N RV+A NK YS + L+T + F D S+H ++ + + TC
Sbjct: 502 GLHFNSTY-NARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTC 560
Query: 320 VEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTA 379
+D DR VLG T
Sbjct: 561 SSYD-----------------------------------------DR------VVLGKTG 573
Query: 380 IESGQHYWEVKAQK--DCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNN---WLQNTFAA 434
G HYWE+ + + + GVA + K LGK + +W ++V+N W +
Sbjct: 574 FSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHN--N 631
Query: 435 KHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQ 471
H N+ + +T IGV D + L+F+ + +Q
Sbjct: 632 SHTNRTEG-GITKGATIGVLLDLNRKNLTFFINDEQQ 667
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 99.0 bits (245), Expect = 1e-20
Identities = 118/538 (21%), Positives = 221/538 (41%), Gaps = 72/538 (13%)
Query: 32 SINLQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILD 91
+I+ + L + L K+ I+ F+ + ++EN S L+E+ + + +
Sbjct: 3541 AISAVKVQLAEFLENLQEKSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVL 3600
Query: 92 EVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQ 151
+ ++ + +K + L Q+ +++ +++ LE R + + F + +
Sbjct: 3601 AQYDEKAQSFEEVKKKKMEFLHEQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEE 3660
Query: 152 IKDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVAD 211
I +R+ A SL+ + D S R Q LK + VP+ P ++P E A
Sbjct: 3661 INERLLSAMESTASLEKMPAAFSLFEHYDDSSARSD-QMLKQVAVPQPPRLEPQEPNSAT 3719
Query: 212 NS-VTVAWRM----------------PEEDNKIDHFILEHR---KTNFDGLPRVKDERCW 251
++ + V W M P++D +++ + E+R K ++ ++ +RC+
Sbjct: 3720 STTIAVYWSMNKEDVIDSFQVYCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLEPDRCY 3779
Query: 252 EIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHL 311
++ + +T G S+ FR + E V T + + +
Sbjct: 3780 QVW--VMAVNFT--GCSLPSERAIFRTAPSTPVIRAE-DCTVCWNTATIRWRPTTPEATE 3834
Query: 312 NLKVEDTCVEWDPTG-GKGQESKIKGKENK----------------GRSGTPSPKRTSV- 353
+E C + P G G S IKG + K GT ++
Sbjct: 3835 TYTLE-YCRQHSPEGEGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALI 3893
Query: 354 ---GSR--------PPAVR----------GSRDRFTGESYTVLGDTAIESGQHYWEVKAQ 392
G+R PA+ G R R T E +VLG+ GQHYWE
Sbjct: 3894 STRGTRFLLLRETAHPALHISSSGTVISFGERRRLT-EIPSVLGEELPSCGQHYWETTVT 3952
Query: 393 KDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTV-PEKI 451
DC +Y +G+ + + LG+ TSW +H + + TF ++ V + VT P ++
Sbjct: 3953 -DCPAYRLGICSSSAVQAGALGQGETSWYMHCSEPQRYTFF--YSGIVSDVHVTERPARV 4009
Query: 452 GVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGF-MVWCGGLSLSTGMQVPSAVR 508
G+ D++ +L F +A S+QLL+ + +F + V P F + G +L G++ P +VR
Sbjct: 4010 GILLDYNNQRLIFINAESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPPDSVR 4067
>gi|46409324 SPRY domain containing 4 [Homo sapiens]
Length = 207
Score = 83.6 bits (205), Expect = 4e-16
Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 4/155 (2%)
Query: 353 VGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQ 412
VG P V + +RF E VL DTA+ SG+HYWEV ++ + + +GVA + +
Sbjct: 57 VGLEPTKVALNVERFR-EWAVVLADTAVTSGRHYWEVTVKRS-QQFRIGVADVDMSRDSC 114
Query: 413 LGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQL 472
+G + SW T A N K + PEK+G+ +++ +LS D + +
Sbjct: 115 IGVDDRSWVFTYAQRKWYTMLA--NEKAPVEGIGQPEKVGLLLEYEAQKLSLVDVSQVSV 172
Query: 473 LYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAV 507
+++ +T F PV+P F +W G L +G++VP +
Sbjct: 173 VHTLQTDFRGPVVPAFALWDGELLTHSGLEVPEGL 207
>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
Length = 550
Score = 82.4 bits (202), Expect = 9e-16
Identities = 72/272 (26%), Positives = 124/272 (45%), Gaps = 20/272 (7%)
Query: 35 LQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVK 94
L + L + ++ L+++ E + F+ L + ++ +QENS + L + D+L L+ K
Sbjct: 272 LHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRK 331
Query: 95 ESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKD 154
++ + +E K + ++ QIS C L + L+E+ + +P F + + +
Sbjct: 332 AQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIR 391
Query: 155 RV--TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFL------PVPKAPEIDPVE 206
RV T + +L P+++ + L +D S Q + L F+ PVP P + E
Sbjct: 392 RVHLTEDQWGKGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEE 450
Query: 207 CLVADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLS 265
C +NS T++W+ P D +ILE N V K T T+
Sbjct: 451 CCTHNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVG---------KETMCTVD 501
Query: 266 GLKFDSKYMNFRVRACNKAVAGEYSDPVTLET 297
GL F+S Y N RV+A NK YS + L+T
Sbjct: 502 GLHFNSTY-NARVKAFNKTGVSPYSKTLVLQT 532
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 82.0 bits (201), Expect = 1e-15
Identities = 53/151 (35%), Positives = 75/151 (49%), Gaps = 9/151 (5%)
Query: 352 SVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTL---G 408
SV P R RFT S VLG + G HYWEV+ QK+ VG+ Y ++ G
Sbjct: 480 SVAEMPQNYRPHPQRFTYCSQ-VLGLHCYKKGIHYWEVELQKN-NFCGVGICYGSMNRQG 537
Query: 409 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDAN 468
+LG+ + SWC+ W +A HNN K L T ++GV + D G + F+
Sbjct: 538 PESRLGRNSASWCVE---WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVA 594
Query: 469 SK-QLLYSFKTKFTQPVLPGFMVWCGGLSLS 498
K L+Y F+ FT+ + P F V+ G +LS
Sbjct: 595 DKVHLMYKFRVDFTEALYPAFWVFSAGATLS 625
Score = 30.8 bits (68), Expect = 3.2
Identities = 33/190 (17%), Positives = 80/190 (42%), Gaps = 7/190 (3%)
Query: 22 LISNITIGPESINLQ----QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILS 77
L+ + T P S++ + L+ ++ + ++ + +D + + + V+ ++ +
Sbjct: 180 LVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVE 239
Query: 78 ELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSL 137
+L +E+ + ++LD + + IK+E+ R + + + + L E +SL
Sbjct: 240 QLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSL 299
Query: 138 DIKEPEEFSKAARQIKDRVTMASAF-RLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPV 196
++ EF + A +++ T + L K+ + +D E + Q + L
Sbjct: 300 TKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNE--LKQCIGRLQE 357
Query: 197 PKAPEIDPVE 206
P DP E
Sbjct: 358 PTPSSGDPGE 367
>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
sapiens]
Length = 749
Score = 80.5 bits (197), Expect = 4e-15
Identities = 77/320 (24%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 193 FLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWE 252
++ P P I E + +V + W N +D + +E L + +
Sbjct: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNL-NPVDSYTVE--------LTQAESPEASG 515
Query: 253 IIDNIKG--TEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSH 310
+ +++ G T ++ L+ Y+ + VRA N S+P T+ T F L+
Sbjct: 516 VTESVVGIPTCESVVQLQPGRSYIIY-VRALNMGGPSVRSEPATVHTIGSYFRLN----- 569
Query: 311 LNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE 370
+DTC W G + + R +PS D
Sbjct: 570 -----KDTCHPWLTISEDGLTAVRSERRTPARELSPS-----------------DTHFTR 607
Query: 371 SYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCI-HVNNWLQ 429
V+G+ G HYWEV+ + Y VGVA+ + K + LG SWC+ H +
Sbjct: 608 CVAVMGNLIPVRGHHYWEVEVDEHL-DYRVGVAFADVRKQEDLGANCLSWCMRHTFASSR 666
Query: 430 NTFAAKHNNKVKALDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGF 488
+ + HN + +TVP +KIG+ D++ +LSF++ + Q LY+F + + V P F
Sbjct: 667 HKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCF 726
Query: 489 MVWCGG-LSLSTGMQVPSAV 507
+ G L + G+ +P V
Sbjct: 727 SLEKPGCLKVHNGISMPKHV 746
Score = 67.0 bits (162), Expect = 4e-11
Identities = 56/255 (21%), Positives = 112/255 (43%), Gaps = 8/255 (3%)
Query: 31 ESINLQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSIL 90
E++ ++ + + + L + E++NF + L V+EN + ++ + L
Sbjct: 207 EALESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETL 266
Query: 91 DEVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAAR 150
+ E I + +++ K + L Q+ C L+ +EL+E + +E +F K A
Sbjct: 267 AQKYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELME-TIEEMCHEEKVDFIKDAV 325
Query: 151 QIKDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDP-VECLV 209
+ DR+ + ++ +DFS Q++ ++ +P P AP I+P V
Sbjct: 326 AMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSA 385
Query: 210 ADNSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKF 269
+SV V W + +D ++ + L +R D P E +K T +++ L
Sbjct: 386 TGSSVRVCWSLYSDDT-VESYQLSYRPVQ-DSSPGTDQA---EFTVTVKETYCSVTNLVP 440
Query: 270 DSKYMNFRVRACNKA 284
+++Y F V A N+A
Sbjct: 441 NTQY-EFWVTAHNRA 454
>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
Length = 353
Score = 80.1 bits (196), Expect = 5e-15
Identities = 51/159 (32%), Positives = 79/159 (49%), Gaps = 1/159 (0%)
Query: 36 QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95
Q+ L IS L ND +Q I L + + +ENS + EL ++FD+LY+ILDE K
Sbjct: 166 QKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKS 225
Query: 96 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQ-IKD 154
++ I QEQ +K +++ I Q L+ S +L+E A +SLD F A+Q IK
Sbjct: 226 ELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKS 285
Query: 155 RVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKF 193
V + +L + +NM +D L+ + F
Sbjct: 286 IVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAIDF 324
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 76.6 bits (187), Expect = 5e-14
Identities = 47/159 (29%), Positives = 83/159 (52%), Gaps = 1/159 (0%)
Query: 36 QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95
Q+ L I+ L ND +Q I L T K ++E EL E+FD LY IL+E K
Sbjct: 168 QKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKN 227
Query: 96 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 155
M I + Q K + +++ I + ++ LEN +L+E + +D E F + A+ + +
Sbjct: 228 EMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKK 287
Query: 156 VTMAS-AFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKF 193
++ AS AF++ +NM H V+ ++E ++++ + F
Sbjct: 288 ISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDF 326
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 76.6 bits (187), Expect = 5e-14
Identities = 47/159 (29%), Positives = 83/159 (52%), Gaps = 1/159 (0%)
Query: 36 QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95
Q+ L I+ L ND +Q I L T K ++E EL E+FD LY IL+E K
Sbjct: 168 QKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKN 227
Query: 96 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 155
M I + Q K + +++ I + ++ LEN +L+E + +D E F + A+ + +
Sbjct: 228 EMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKK 287
Query: 156 VTMAS-AFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKF 193
++ AS AF++ +NM H V+ ++E ++++ + F
Sbjct: 288 ISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDF 326
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 76.6 bits (187), Expect = 5e-14
Identities = 47/159 (29%), Positives = 83/159 (52%), Gaps = 1/159 (0%)
Query: 36 QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95
Q+ L I+ L ND +Q I L T K ++E EL E+FD LY IL+E K
Sbjct: 168 QKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKN 227
Query: 96 SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 155
M I + Q K + +++ I + ++ LEN +L+E + +D E F + A+ + +
Sbjct: 228 EMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKK 287
Query: 156 VTMAS-AFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKF 193
++ AS AF++ +NM H V+ ++E ++++ + F
Sbjct: 288 ISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDF 326
>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
Length = 432
Score = 71.2 bits (173), Expect = 2e-12
Identities = 48/148 (32%), Positives = 74/148 (50%), Gaps = 8/148 (5%)
Query: 349 KRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLG 408
+ +V RP R S +RF+ VL A+ SG+HYWEV ++C ++VGVA +
Sbjct: 279 RTVTVSHRPQPYRWSCERFSTSQ--VLCSQALSSGKHYWEVDT-RNCSHWAVGVASWEMS 335
Query: 409 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDA- 467
+ LG+T S C+ Q +A H K L P +G++ + + G+L+FY
Sbjct: 336 RDQVLGRTMDSCCVEWKGTSQ--LSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVD 393
Query: 468 NSKQLLYSFKTKFTQPVLPGFMVWCGGL 495
N ++LLY + P+ P F W GL
Sbjct: 394 NQEKLLYECTISASSPLYPAF--WLYGL 419
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 69.3 bits (168), Expect = 8e-12
Identities = 96/425 (22%), Positives = 171/425 (40%), Gaps = 66/425 (15%)
Query: 69 QENSSNILSELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCNNALENSEE 128
+ N + E +F +L+ VK+ I C + + K Q+ I A E
Sbjct: 89 KRQKENAMCEKHNQFLTLFC----VKDLEILCTQCSFSTKHQK--HYICPIKKAASYHRE 142
Query: 129 LLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQML 188
+LE + E +++ + + + + LK KV + +F Q R L
Sbjct: 143 ILEGSL--------EPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEFEQIRLFL 194
Query: 189 QTLKFLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFI--LEHRKTNFDGLPRVK 246
Q E + + + D + + ++ E ++ ++ L+H +G
Sbjct: 195 QN----------EQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQS 244
Query: 247 DERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSD-PVTLETKALNFNLD 305
+ E++ K + LK + +FR+ ++ +YS ++ ++ LD
Sbjct: 245 N---LELLTQAKSMHHKYQNLKCPELF-SFRLTKYGFSLPPQYSGLDRIIKPFQVDVILD 300
Query: 306 NSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRD 365
+++H L V + + K E K R+ P+R V PAV GS+
Sbjct: 301 LNTAHPQLLVSE-------------DRKAVRYERKKRNICYDPRRFYVC---PAVLGSQ- 343
Query: 366 RFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKF--DQLGKTNTSWCIH 423
RF+ SG+HYWEV+ K + +GV L + DQ W I
Sbjct: 344 RFS-------------SGRHYWEVEVGNKPK-WILGVCQDCLLRNWQDQPSVLGGFWAI- 388
Query: 424 VNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQP 483
++++ + A + L V P KIG+F D++ G LSFY+ N + +LY+F FT+
Sbjct: 389 -GRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEA 447
Query: 484 VLPGF 488
V P F
Sbjct: 448 VWPYF 452
>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
Length = 358
Score = 68.6 bits (166), Expect = 1e-11
Identities = 43/167 (25%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Query: 30 PESINLQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSI 89
P Q+ L I+ L ND +Q I + + +++NS L++ F+SL ++
Sbjct: 164 PTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAV 223
Query: 90 LDEVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAA 149
L+E K ++ + +EQ K Q ++ I Q + LE S +L+E A +S++ + + + A
Sbjct: 224 LEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQA 283
Query: 150 RQIKDRVTMASAFRLSLKPKVS-DNMTHLMVDFSQERQMLQTLKFLP 195
+++ ++V S L+ +P+ ++M V +ML+T+ F P
Sbjct: 284 KELINKVGAMSKVELAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQP 330
>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
Length = 400
Score = 67.0 bits (162), Expect = 4e-11
Identities = 40/153 (26%), Positives = 81/153 (52%), Gaps = 1/153 (0%)
Query: 44 ISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQ 103
I+ L ND +Q I + + +++NS L++ F+SL ++L+E K ++ + +
Sbjct: 220 IAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAR 279
Query: 104 EQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFR 163
EQ K Q ++ I Q + LE S +L+E A +S++ + + + A+++ ++V S
Sbjct: 280 EQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVE 339
Query: 164 LSLKPKVS-DNMTHLMVDFSQERQMLQTLKFLP 195
L+ +P+ ++M V +ML+T+ F P
Sbjct: 340 LAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQP 372
>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 66.6 bits (161), Expect = 5e-11
Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 8/132 (6%)
Query: 372 YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGK-----FDQLGKTNTSWCIHVNN 426
+ VL +G+HYWEV Q+ + VG AY +L + +LG SWC+ +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368
Query: 427 WLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYD-ANSKQLLYSFKTKFTQPVL 485
F ++++ D +++GVF D++ G L+FYD L++F+ F +P+
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426
Query: 486 PGFMVWCGGLSL 497
P +W G +S+
Sbjct: 427 PALRLWEGAISI 438
>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 66.6 bits (161), Expect = 5e-11
Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 8/132 (6%)
Query: 372 YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGK-----FDQLGKTNTSWCIHVNN 426
+ VL +G+HYWEV Q+ + VG AY +L + +LG SWC+ +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368
Query: 427 WLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYD-ANSKQLLYSFKTKFTQPVL 485
F ++++ D +++GVF D++ G L+FYD L++F+ F +P+
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426
Query: 486 PGFMVWCGGLSL 497
P +W G +S+
Sbjct: 427 PALRLWEGAISI 438
>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 66.6 bits (161), Expect = 5e-11
Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 8/132 (6%)
Query: 372 YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGK-----FDQLGKTNTSWCIHVNN 426
+ VL +G+HYWEV Q+ + VG AY +L + +LG SWC+ +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368
Query: 427 WLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYD-ANSKQLLYSFKTKFTQPVL 485
F ++++ D +++GVF D++ G L+FYD L++F+ F +P+
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426
Query: 486 PGFMVWCGGLSL 497
P +W G +S+
Sbjct: 427 PALRLWEGAISI 438
>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
Length = 526
Score = 62.4 bits (150), Expect = 1e-09
Identities = 37/124 (29%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 374 VLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGK--FDQLGKTNTSWCIHVNNWLQNT 431
VLG SG+HYWEV+ D +++GV + + K FD + N W + + N
Sbjct: 347 VLGRETFTSGRHYWEVEVG-DRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYG---NG 402
Query: 432 FAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSF-KTKFTQPVLPGFMV 490
+ A + P ++G+F D++ G +SFY+ N +Y+F F+ P+ P F +
Sbjct: 403 YWALTPLRTPLPLAGPPRRVGIFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFCL 462
Query: 491 WCGG 494
W G
Sbjct: 463 WSSG 466
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,721,097
Number of Sequences: 37866
Number of extensions: 913540
Number of successful extensions: 3571
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 2971
Number of HSP's gapped (non-prelim): 644
length of query: 530
length of database: 18,247,518
effective HSP length: 107
effective length of query: 423
effective length of database: 14,195,856
effective search space: 6004847088
effective search space used: 6004847088
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.